Instagram is a social media that has a shopping feature. Instagram can be used for digital advertising, and among them is paid promotion. Paid promotion is a service to promote goods/services on social media. This service offers advantages such as a broad market segment, low cost, and easy technical implementation. Many online shops are willing to spend a lot of money to be promoted. Unfortunately, online shop owners usually do not know how Instagram users respond when they see a paid promotion. Therefore, the purpose of this study is to find out how Instagram users respond to the paid promotion on Instagram. User response data was taken from a questionnaire, then analyzed using the CRI method with the AISAS concept by using 4 models: AISAS, AISS, AIAS, and AIS. As the result, four models showed the CRI is below 50% (AISAS: 2,8%; AIAS: 3%; AISS: 4,5%; AIS: 8,4%). Considering the result, the respondents do not give a good response to the paid promotion service.


due to a complicated endocrinologic picture " (p. 580, Revie'wer's italics). For this we may perhaps forgive the author. Endocrinology and vague statement appear to be indissolubly wedded. Further, though it is true that blue naevi can " develop into tumours that are extremely malignant " (p. 607), such a change, as Traub has pointed out, must be rare, since he says that neither Satenstein, Becker, Peck, Ewing, Wood nor Fraser have seen examples of it. It is the blue-black melanoma that is dangerous. But the sections which are good are very good, and they more than counterbalance the defects. We would instance especially the chapters on alopecia and fungus diseases. The space given to the latter would appear to be in pious memory of Dr. Lee McCarthy's early teacher, Raymond Sabouraud, to whom the book is dedicated. A full and interesting historical account is given of the early mycological work and the controversies it aroused. There are numerous excellent photographs, many of which are taken from the author's own cases. A good bibliography is appended to each chapter. And a feature which should recommend the book particularly to the student or practitioner is the use of brief and clear summaries to epitomize long discussions. A. C.


The Story of the Progress in Medicine. By C. F. V. Smout. (Pp. 168; illustrated; 30s.) Bristol: John Wright. 1964. The writing of history has many purposes, such as tracing a line of thought or series of ideas, studying the effects of circumstances on persons or situations, or studying the influences of a person or a group on the times in which they lived. Some history can justly be an interesting story giving pleasure and food for thought to the reader. This new addition to the accounts of the progress of medicine traces the story of medicine from the Creation to the National Health Service. Obviously it has to be selective, and this requires an underlying idea or warp thread to run through the book. It also requires courage, courage to cut persons, places or events right out if they do not fit in. A brief reference, or, worse, a series of brief references, breaks the narrative and contributes little. Thus, we are told of Sir Charles Bell: 'A great surgeon of this period was Sir Charles Bell (1774-1842), whose discoveries are rated next to Harvey's in importance. He confined his researches to the nervous system and carried considerably further some of Galen's original ideas.' Industrial physicians will turn to the chapter on 'Victorian Medicine' and will be disappointed to find a number of misleading statements. Students of industrial medicine would be advised not to learn their history from these pages. This book is well produced. It is profusely illustrated and is printed in clear type. Although in places the writing is a little stilted, there is a deal of interesting information. It is a handy little book which can be dipped into but should not be regarded as authoritative.


Despite high clinical disease activity, some patients with active rheumatoid arthritis (RA) have normal acute phase reactant (APR) values. This study aimed to determine the clinical outcomes of active RA patients with normal APR values.


In this study, nano-sized particles of manganese oxyhydroxide (MnO(OH)) are synthesized. Sorption properties of this material towards 90Sr and 137Cs radionuclides in the pH range from 2 to 9 at a temperature of 293.15 K solution are studied. The time of sorption achievement equilibrium in the radionuclide sorbent system depends on the nature of sorbed cation, but does not exceed 60 min.


By extensive use of commercial x‐ray diffractometer components considerable reductions of cost and time, necessary for the design of single crystal neutron diffractometers, can be achieved. This example shows, that the Nicolet Instr. diffractometer control system can be adapted to an instrument of different origin though larger and heavier in its dimensions.


This article provides a brief critique of presumptions about parenting and children seen through the lens of family law. It argues that, historically, decisions largely followed gender-based and/or moral presumptions of the day and that sometimes these were in tension with each other. Sometimes, too, as in the biblical story of Solomon's judgment, biological parenthood was contested and/or gender did not provide a ready answer. The article argues that, as children's rights and the best interests of the child increasingly came to dominate the decision-making rhetoric, a Solomon-like belief has nonetheless persisted, that judicial ingenuity and sophisticated investigative resources can determine the underlying truth of a dispute and lead to the correct outcome. The evidence, however, points in the direction of significant predictive limitations to the legal, social, and psychological knowledge bases supporting most postseparation parenting decisions. It is argued that what is needed is a formal shift in emphasis from a somewhat idealized commitment to discovering the truth in most contested cases to a focus on good decision-making processes. It is suggested that most transitional families are best served by an emphasis on good, respectful processes associated with good-enough decisions that formally acknowledge the limitations of our capacity to predict. Good processes and good-enough decisions are in turn best supported by a clear emphasis on children as individual agents, who, though dependent on adults, are entitled to the full panoply of human rights.


Coal might be co-gasified with waste or biomass for environmental, technical or commercial reasons. It allows larger, more efficient plants than those sized for the biomass grown or waste arisings within a reasonable transport distance; specific operating costs are likely to be lower; and, fuel supply security is assured. This review paper assesses the current status of co-gasification technologies and quantifies the potential future demand for such plant. It aims to identify and prioritise areas where further RD (ii) fuel gas clean-up; and, (iii) conversion of fuel gas to electric power. The integration of these into commercially viable systems is considered in general terms. In this paper, the term "waste" is used in the broadest sense to include municipal solid waste (MSW), refuse derived fuel (RDF), scrap tyres, sewage sludge, wood waste and any other commercial/industrial waste but excluding hazardous wastes. Although the latter can usually be safely gasified, the special handling precautions upstream of the gasification process have not been considered.


Cilia and flagella were one of the characteristic traits of the last eukaryotic common ancestor and as such, are highly conserved among eukaryotes. Their proteomic makeup is consequently remarkably similar throughout all eukaryotic lineages. Recently, one subgroup of ciliary transport proteins in mammalian cells, the Bardet-Biedl Syndrome (BBS) proteins, was shown to have the ability to traverse the nuclear envelope, and to engage in protein-protein-interactions that modulate gene expression, signalling cascades, and cell homeostasis. Insects have been critically understudied in cilia biology because of their highly specialised cilia being localised on only a small subset of cell types. In this study, we present evidence that the BBSome, a hetero-octameric ciliary transport complex of BBS proteins, is largely conserved in multiple insect lineages. Using the honeybee Apis mellifera as a study system to explore BBS-associated gene expression, our analyses suggest that not all BBSome-associated genes are expressed equally, indicating possible non-ciliary functions. We also demonstrate that the expression of individual BBS proteins varies significantly between the tissues of queens and males in A. mellifera, especially in neuronal tissue. This result raises the question of what role BBS proteins play in these tissues and whether they are involved in gene regulation in insects. The potential gene regulatory function of BBS proteins should be explored in other eukaryotes due to their high degree of conservation.


A distinguished historian examines the nation s involvement in a war that most americans thought necessary and righteous. He focuses on the home front: how our culture and politics affected the course of the war and how the war in turn affected us. Index."


In this paper, the treatment of patients with severe aneurysmal subarachnoid hemorrhage of Fisher's classification III alone is persented, applying acute surgery and pharmacological prevention of symptomatic vasospasm. Calcium-antagonist flunarizine is administered orally from just after early operation until 22 days after subarachnoid hemorrhage. The results in a series of 16 patients showed no permanent ischemic neurologic deficits from delayed vasospasm: on the other hand, the same number of patients who were not treated by flunarizine showed six permanent ischemic neurologic deficits including three deaths due to delayed vasospasm. There were no side effects from flunarizine. From this evidence, it might be concluded that flunarizine significantly inhibits the occurrence of severe neurological deficits due to delayed vasospasm. This highly benefical effect might be attributable to its intense inhibitory action on cellular Ca2+ overload.


The engineering and construction mechanic development is of vital importance to Hunan's industrialization process.This paper analyzes the circs of engineering and construction mechanic in Hunan province,combined with the theory on relation of industrial chain and industrial clusters competitiveness,deduce the conclusion that we must rely on industrial chain,put the essential power on industrial inside and outside,linkage dominant industrials and core products.


The aim of this study was to evaluate the clinical-epidemiological profile of oral health in leprosy patients at multidrug terapy (MDT) through the oral mucosa clinic assessment, the VPI (visible plaque index), GBI (gum bleeding index), DMFTI (decayed, missing and filled teeth index) and salivary flow rate measure by SSI (salivary secretion index) as epidemiological indicators, well over buffeing capacity by salivary pH. The sample was 80 patients, aged from 8 to 73 years submited to the analysis of the oral conditions and stimulated saliva collection, divided in study group (SG) constituted of 40 leprosy patients in MDT carried in the CRTDS Dr. Marcello Candia Marituba-Pa, Brazil and control group (CG) of 40 no leprosy patients. The results pointed 62,5% unspecific oral lesions, among the most frequent was melanin pigmentation of the attached gingiva, mordiscatum line of the buccal mucosa, gingival inflammation, tongue varicose veins and trauma for use of prosthesis, without statistical significant difference (p=0,14) with the CG. The average of the VPI was 50,4 % of the dental surfaces with accumulation of bacterial plaque, without statistical significant difference (p=0,40) with the CG. The VPI was bigger in the individuals without access to the odontologic service and while it increased the degree of incapacity of the patients, juvenile was the access to the service. The average of the GBI was 29,7% of the dental surfaces with gingival bleeding, without statistical significant difference (p=0,35) with the CG. The middle DMFTI was of 11,6 varying from 4,0 to 24, which increases with the advancement of the age. The biggest accumulation of plaque, the gingival bleeding and the consumption of foods cariogenic out of the time-table of the meal also contributed to the increase of the DMFTI. Another factor made a list to the increase of I DMFTI was no access it to the odontologic service for 70 % of the leprosy patients, having statistical significant difference is (p=0,0005) with the CG and the lack of education of oral hygiene in 60 %, having statistical significant difference (p=0,01) with the CG. The middle SSI was of 0,9ml/min and did not present association with the MDT and not even with the use of prednisolone. The SG patients, 25 % presented hiposalivation, but there was no increase of DMFTI and none of the groups revealed alteration of salivary pH , varying from 5,85 to 7,34, with buffeing capacity inside the standard of normality. Conclusion that the clinical-epidemiological profile of leprosy patients is similar to the control group, do not have find specific oral lesions for leprosy, which does not cancel the possibility of the buccal cavity to be a fountain of infection for leprosy, needing histopathological confirmation and / or PCR for detection of viable M.leprae. Moreover, the data showed most of the leprosy patients do not have access to the odontologic service and not even education of oral hygiene, results absence of public politics of oral health for leprosy. Key-words: Leprosy. Oral Health. Oral Mucosa. Saliva.


This paper presents a channel allocation model with dynamic priority support for cellular networks. Channels within a cell are divided into high and low priorities, while user calls are also differentiated by high and low priorities. High-priority channels can provide better QoS than low-priority channels. One of the innovatory designs is right in that if there are no high-priority channels available for a high-priority call, the high-priority call may dynamically downgrade its priority levels by sacrificing some QoS demands to utilize the low-priority channels. We analyze the proposed channel allocation schemes through a mathematical model. In the model, we build 4-D Markov chains and use MATLAB tool to evaluate blocking probability, call-incomplete probability, and channel utilization under different traffic loads. It is observed that the blocking probability of high-priority handoff and new calls can be substantially decreased and the channel utilization is increased, as compared to that of low-priority handoff and new calls.


Pressure drop calculation for horizontal wells is theoretical basis of the productivity prediction,horizontal section length selection,and the completion design optimization.Meanwhile,hydraulic calculation for singlephase flow is the foundation of the pressure drop prediction for more complex oil / water two-phase flow or gas / oil / water three-phase flow.Based upon the pressure drop modeling presented by Su who is an important investigator in the field of variable mass flow,considering the inaccurate prediction results of the model,a new improved model of single-phase flow in the horizontal wellbore is developed.The new model is implemented by using the VB.NET software and compared to the Su model.Results show that the proposed model corresponds better to the practical situation and could be easily used to predict the total pressure drop of single-phase flow in the horizontal wellbore with perforated completion.


The homology with coefficients in a field of the configuration spaces C(M × Rn, Mo × R n; X) is determined in this paper.


Study Selection: A total of 1282 relevant articles published up to 2018 were identified. The selected papers were screened based on the eligibility criteria after the thorough investigation of their titles and abstracts. In the next step, the inconsistent articles with our objectives were removed. Afterward, the papers were thoroughly studied, and data related to our study goals were extracted and recorded in predetermined extraction forms. After the full-text evaluation of the articles, 22 articles were finally selected.


【Cigarette smoking has been identified as the most important source of preventable morbidity and premature mortality (WHO, 1995), The prevalence of smoking among men is very high in Korea. This study estimated productivity losses due to smoking in Korea, 1997. The derivation of cost estimates for mortality, disability, hospitalization and use of physician services related to cigarette smoking is bas 어 on the calculation of attributable fractions suggested by MacMahon and Cole and Smoking-Attributable Mortality, Morbidity, and Economic Cost(SAMMEC) software. To estimate the number of deaths from neoplastic, cardiovascular, respiratory diseases associated with cigarette smoking, estimates for adults(aged 20 years and over) were based on 1997 mortality data, 1995 data on smoking prevalence from Korea Institute for Health and Social Affairs. Smoking-attributable indirect morbidity cost data were obtained from the National Federation of Medical Insurance. As the result of cost estimation, these productivity losses were 336-430 billion won. During 1997, 8,620-10,804 deaths were attributed to smoking. Cigarette smoking resulted in 133,991-169,422 Years of Potential Life Lost (YPLL) to life expectancy. For smoking -attributable indirect mortality costs, the present value of future earnings(PVFE) for the age at death are 299-384 billion won. Smoking-attributable indirect morbidity costs, the costs of lost productivity for persons who are disabled by smoking-related chronic diseases are 37-46 billion won. In this study the productivity losses due to smoking were restricted to the health effects of smoking. It is possible that these costs were underestimated with the limitation of the data. Smoking is the leading preventable cause of illness and death. The results of this study can be used as elementary data for antismoking policy.】


It is shown that the interaction between components of the microcrystalline cellulose - trichlorophene (MCC - TCP) system can proceed via the formation of intermolecular (hydrogen) bonds and even covalent bonds, depending on the intensity of treatment and the method of mixing. These interactions have predominantly a topochemical character. For this reason, various hypotheses concerning the possible formation of new chemical substances possessing certain molecular and chemical structure and definite physicochemical properties are not valid. This conclusion is confirmed by the data of IR spectroscopy. Therefore, MCC - TCP reaction products may possess no specific biological activity different from that of the system components. Only the formation of a relatively small number of bonds between MCC and TCP retains the activity of TCP at a significantly increased drug release time.


We extend the boson process first to a large class of Cox processes and second to an even larger class of infinitely divisible point processes. Density and moment results are studied in detail. These results are obtained in closed form as weighted permanents, so the extension is called a permanental process. Temporal extensions and a particularly tractable case of the permanental process are also studied. Extensions of the fermion process along similar lines, leading to so-called determinantal processes, are discussed.


Our article is a new reading of the novel «Friday and Robinson» (�Vendredi ou la Vie sauvage�) of the writer Michel Tournier. It is a playful reading based on the concept of carnival, proposed by Mikhail Bakhtine and on the game theory proposed by Roger Caillois.


Telcordia has submitted proposals to standards bodies for the specification of two easily implemented security services, SSL/TLS and IPSec, that can provide a substantial defense for the home. We show how these services would be implemented in both user devices on the home network and in the residential gateway, and describe the cooperation that would be necessary to effect home network security.


The JK ring fragment (7) of 42,43,44,45,46,47,55-heptanor-41-oxoyessotoxin was synthesized via enyne metathesis and 6-exo cyclization of a hydroxy epoxide. Conversion of 7 into the JK ring fragment (6) of yessotoxin was achieved in a single step by treatment with an alkenyllithium.


There is new evidence to suggest that schools should deploy their best teachers to Reception. A wide-scale research testifies to how children's progress at this stage can determine their future edu...


In Indonesia pesantren is known as the indigenous religious educational institution. The basic elements of pondok pesantren are: Kiai as a central figure, santri as a student who persues knowledge, pondok as dormitory where santri lives, and mosque which constitutes at the centre of educational activities. In general, due to the system and method of teaching, pondok pesantren classified into two kinds; traditional and modern. Never the less they are having the same vision and mission, that is to say that education is pondok pesantren is community oriented education by cultivating values, moral attitude, and character building of muslim community. That is the main reason that life atmosphere inside pesantren is in inspired strongly by what so called Panca Jiwa – Five Spirits – namely; sincerity, simplicity, self-reliance, Islamic brotherhood, and accountable freedom. In modern Indonesia today the expectation towards the role ofpesantren move on since early twentieth century, it is not only performing it's three traditional roles as locus for transforming religious education, preserving muslim traditions, and producing scholars, but nowadays it plays an important role to educate and prepare leaders of tomorrow who posses specific qualities.


Summary The progressive deregulation of the Australian financial system, promulgated by the Campbell Committee of Inquiry (1981), has created major pressures for structural readjustment in the Australian banking industry. Recent moves by the ANZ to take over Grindlays, the British‐based international bank, is the first significant attempt at comprehensive internationalising by an Australian bank. The takeover is analysed in terms of the model of bank internationalisation developed by Fujita and Ishigaki. Particularly attractive to the ANZ is the foreign bank representation that Grindlays possesses. This not only complements the ANZ's existing international representation, but also allows the Australian purchaser to overcome the regulatory impediments of reciprocity that have prevented Australian banks operating in many offshore locations. Disadvantages of the merger for the ANZ include exposure to Third World debt and the acquisition of branches in areas of limited interest to the Australian parent where ...


Due to the excellent mechanical properties of doubly curved structure and functionally graded porous (FGP) material, the study of their vibration characteristics has attracted wide attention. The main aim of this research is to establish a formulation for free and forced vibration analysis of a new Sandwich FGP doubly curved structure. Four models of Sandwich materials are considered. The potential energy and kinetic energy functions are obtained on the foundation of the first-order shear deformation theory (FSDT). The idea of domain energy decomposition is applied to the theoretical modeling, where the structure is segmented along the generatrix direction. The continuity conditions for the interfaces between adjacent segments are balanced by the weighted parameters. For each segment, the displacement functions are selected as the Jacobi orthogonal polynomials and trigonometric series. The boundary conditions of the structure are obtained by the boundary spring simulation technique. The solution is obtained by the variational operation of the structural functional. The convergence performance and correctness of the theoretical model are examined by several numerical examples. Finally, some novel results are given, where free and forced vibration characteristics of Sandwich FGP doubly curved structures are examined in detail.


This study deals with the comfortableness of wave sounds from physiological and psychological aspects. Firstly, the difference of wave sound generation mechanisim between plunging and spilling breakers is discussed on basis of the variation characteristics of sound pressure level and the volume of air bubbles in water. Secondly, the comfortableness of wave sounds is investigated based on the genaration characteristics of the brain wave and the result of questionnaire surveys of auditory test.


The invention relates to a local coil means (8) for a magnetic resonance imaging device (5) for inspecting an object to be examined (1) with an antenna housing (12) for covering a high-frequency antenna (9) and at least one conditioning electronics (10), wherein the antenna housing ( 12) has at least one object-side wall (13) and at least one object remote wall (14). In order to minimize the attenuation of PET radiation in a combined MR-PET apparatus, thereby ensuring in particular in PET measurement to an improved signal-to-noise ratio, it is proposed according to the invention that the surfaces of the object remote wall (14) is substantially tangential to the examination subject (1).


Glycation stress is a concept of biological stress caused by excess sugars, aldehyde and its subsequent reactions in the body. Especially, it is thought that accumulation of Advanced Glycation End products (AGEs) cause skin yellowing, deep wrinkles and a decrease in skin elasticity due to crosslinking to collagen or elastin in the dermis. We have reported that phlorotannins, polyphenols unique to brown algae, could inhibit the formation of N-ε-carboxymethyllysine resulting from glycation of collagen. The aim of this study was to investigate the anti-glycation and skin protection effects against UV exposure by long-term intake of the brown algae extract powder containing phlorotannins as a supplement. This study have performed a randomized, double-blind, placebo-controlled, parallel group study. Forty-two healthy Japanese adult female were randomly divided into two groups: one group consuming supplements containing brown algae extract powder (Phlorotannins intake group) and the other group consuming supplements not containing brown algae extract powder (placebo group). In both groups, each supplement was consumed daily, and blood AGEs concentration and Minimal Erythema Dose were measured every 4 weeks. In addition, the condition of skin was analyzed by using the skin image analyzer. In this presentation, we will introduce the skin protection effect against UV exposure and the anti-glycation effects by consuming the brown algae extract powder for eight weeks.


Introduction: Central visual field examination is a great clinical interest in diabetes mellitus, since changes in the visual field would be accepted as an indication of pathological condition. Hence, it is reflecting structural abnormalities in the ocular and the neural mechanisms of vision. The central visual field was examined in this study to investigate possible early changes in the macular area with a view to providing an assessment of early neural functional integrity in the presence of no or minimal diabetic retinopathy. Materials and Methods The investigation was carried out on a healthy visual system control group and a number of age-and sex-matched non-insulin dependent diabetic groups with different levels of diabetic retinopathy. The psychophysical test used was Oculus Tubingen perimeter. Results: The results were considered in terms of the presence of functional changes relative to the severity of retinopathy and the duration of diabetes. The visual fields test differentiated between normals and those with diabetes but with retinopathy. The test failed to differentiate between normals and diabetics without retinopathy. Conclusion: Visual filed defects are not strongly related to the duration of diabetes, but more to the severity of the retinopathy. They can be correlated to areas of capillary non-perfusion.


ML | Introduction to Kernel PCA GeeksforGeeksINTRODUCTION MACHINE LEARNINGUsing CSS gradients CSS: Cascading Style Sheets | MDNOtitis, Sinusitis, and Mastoiditis(PDF) Introduction to Regression AnalysisVORTEX DYNAMICS


NASA's Kepler spacecraft, launched in 2009, has been a resounding success.More than 4000 planet candidates have been identified using data from Kepler primary mission, which ended in 2013, and >2000 of these candidates have been verified as bona fide exoplanets.After the loss of two reaction wheels ended the primary mission, the Kepler spacecraft was repurposed in 2014 to observe many fields on the sky for short periods.This new mission, dubbed K2, has led to the discovery of >600 planet candidates, ~200 of which have been verified to date; most of these exoplanets are closer to us than the majority of exoplanets discovered by the primary Kepler mission.TESS, launching in 2018, will survey most of the sky for exoplanets, with emphasis on those orbiting nearby and/or bright host stars, making these planets especially well-suited for follow-up observations with other observatories to characterize atmospheric compositions and other properties. More than one-third of the planet candidates found by NASA's are associated with target stars that have more than one planet candidate, and such "multis" account for the majority of candidates that have been verified as true planets.The large number of multis tells us that flat multiplanet systems like our Solar System are common. Virtually all of the candidate planetary systems are stable, as tested by numerical integrations that assume a physically motivated mass-radius relationship. Statistical studies performed on these candidate systems reveal a great deal about the architecture of planetary systems, including the typical spacing of orbits and flatness. The characteristics of several of the most interesting confirmed Kepler & K2 multi-planet systems will also be discussed. https://ntrs.nasa.gov/search.jsp?R=2018000212


The simple shearing of a suspension of charge‐stabilized, colloidal particles close to the melting line is investigated by massively parallel, nonequilibrium Brownian dynamics (NEBD) simulation. The suspension undergoes a discontinuous transition from a distorted fluid structure to an ordered ''string'' phase. Comparisons between simulations of 43 000, 4725 particles, and previous NEBD work on ≤500 particles proves that shear‐induced ordering is not an artifact of the small system sizes. We also show that the shear‐rate dependence of the rheological properties obtained from NEBD is different than those obtained from nonequilibrium molecular dynamics (NEMD), a consequence of the solvent damping not being present in NEMD. The validity of the Ree–Eyring model for viscosity and the stress‐optic law for colloids are tested. Further, a type of generalized Stokes–Einstein relationship is discovered for systems under shear.


Ohio's Career Development Blueprint is a key component of the state's career development program. The blueprint is a document that includes learner outcomes, indicators, and suggested classroom activities organized by 12 key topic areas: self-awareness, career information, academic planning, future trends, economics, vocational orientation, self-assessment, career exploration, reduction of bias, employability skills, community involvement, and decision making/goal setting. The blueprint is available in three versions--for grades K-5, 6-8, and 9-12. All three versions incorporate the National Career Guidance and Counseling Guidelines that were developed by the National Occupational Information Coordinating Committee. In the blueprints, the following items are provided for each of the 12 topics: definition; one to three learner goals and numerous indicators to define the goals; several activities to help students master the leaner goals; and suggestions for integrating the concepts into the classroom. Career activity packets, another popular resource for elementary and middle grade teachers and counselors, are also available from the Career Development Service of the Ohio Department of Education. Each 8to 10-page packet contains ready-to-use classroom ideas (worksheets, bulletin board ideas, small units of study, and teacher ideas) that have been developed by master teachers. (MN) ******************************************************************************** * Reproductions supplied by EDRS are the best that can be made * * from the original document. * ******************************************************************************** U.S. DEPARTMENT OF EDUCATION Of tice ot Educational Research and Improvement E CATIONAL RESOURCES INFORMATION CENTER (ERIC) This document has been reproduced as received from the person or organization originating it. 0 Minor changes have been made to improve reproduction quality. Points of view or opinions stated in this document do not necessarily represent official OERI position or policy. PERMISSION TO REPRODUCE AND DISSEMINATE THIS MATERIAL HAS BEEN GRANTED BY TO THE EDUCATIONAL RESOURCES INFORMATION CENTER (ERIC) 1 American Association For Career Education AACE Bonus Brief Ohio's Career Development Blueprint and Career Activity Packets: Resources for the Classroom Educator Cynthia Gahris This is the third in a series of articles for AACE about Ohio's Career Development Program. Previous articles featured the Individual Career Plan (ICP) and the Career , Passport, and the network of career coordinators Ohio has in place. To help the career coordinators in their work with Ohio's K-12 educators, and to provide continuity in career classroom activities, we have developed resources that are used statewide. We believe that career development should be infused or integrated into all K-12 curricula and classroom activities. Because of this philosophy, we have not developed a statewide course of study for Career Development. Instead, we encourage educators to use Ohio's Career Development Blueprint, a document that includes learner outcomes, indicators, and suggested classroom activities organized by 12 key topic areas. The Blueprint is available in three versions: K-5, 6-8, and 9-12, and incorporates the National Career Guidance and Counseling Guidelines developed by the National Occupational Information Coordinating Committee. The 12 key topic areas found in the Blueprint are the following: Self-Awareness Career Information Academic Planning Future Trends Economics Vocational Orientation Self-Assessment Career Exploration Reduction of Bias Employability Skills Community Involvement Decision Making/Goal Setting Each key topic is defined in the Blueprint, and has one to three learner goals assigned. Following each learner goal are numerous indicators to define the goal. Then, several activities are suggested to help students master the learner goals, and to give educators ideas about how the concepts can be integrated in the classroom. Many of our K-12 educators still don't realize that Career Development involves more than simply providing students with information about jobs. The Blueprint helps educators see the entire scope of Career Development, and helps dispel the myth that career activities are only for high school students and are only done by the guidance counselor. This document defines the specific and developmentally appropriate career skills students need to learn. The Career Development Service of the Ohio Department of Education offers another popular resource for elementary and middle grade teachers and counselors. We feel that educators need to be given new career integration ideas as frequently as possible. To achieve that, each summer we bring together a small group of career coordinators and local educators who are particularly creative. This group develops 18 activity packets (nine each for elementary and middle school) which are then distributed on a monthly basis to the 89 career coordinators across the state. They, in turn, duplicate the activity packets and share them with classroom teachers and counselors. This ensures that, every month, K8 educators are given new integration ideas for career activities. 2900 Amby Place . Hermosa Beach, California 90254-2216 Phone (310) 376-7378 . Fax (310) 376-2926 litEST COPY AVALIABLE Page 2 AACE Bonus Brief February 1999 Cynthia Gahris Ohio's Career Development Blueprint and Career Activity Packets: Resources for the Classroom Educator Each 8-10 page packet contains ready-to-use classroom ideas. The packets include worksheets, bulletin board ideas, small units of study, and teacher ideas. Not only are they written by master educators, they are also illustrated by four art teachers in the state who are particularly skilled in black line drawings. The illustrations add great graphic appeal for students. For the past few years, each monthly packet has focused on a different curriculum area. We feature language arts, math, science, and social studies on a rotating basis. In addition, one packet each year focuses on a unique topic. For example, last January's elementary packet featured career infusion ideas to use with the Winter Olympics. The key topics (from the Blueprint) that each activity addresses are listed at the bottom of the packet page so educators continually see the scope of Career Development. If the activity supports one of the learner goals for the Ohio Proficiency Test, that goal is also listed at the bottom of the packet page. This helps educators understand that career activities are not separate from subject area curricula, but are a great support to subject content. Last year we also included one Home Connection page in each packet. This page contains a career activity that parents or guardians can do with their children at home. For example, one Home Connection page in a packet that featured social studies asked elementary students to complete a technological timeline with their parents or guardians. After interviewing adults about the technological changes seen in their lifetimes, students had to identify the changes and plot them according to decade on the timeline. They also had to indicate how this change impacted the adult's career. The adults and children then had to forecast future technological changes and mark those on the timeline. These Home Connection pages help us to get parents and guardians more involved in their children's career thoughts and dreams, and, eventually, in their career decision-making process. Although we do not offer packets to high school educators, they do have a state resource for career integration ideas. The Ohio Career Information System (OCIS) is a computerized career system that 95% of our high schools have. It contains files that provide occupational information as well as information about higher education facilities across the country. Another file in OCIS contains approximately 400 ideas for secondary career curriculum integration. Like the career packets, this file (called PLAN) offers bulletin boards, worksheets, teacher ideas, and small units of study--all by curriculum area. The PLAN file is updated about every 3 years, so it can be a source of new ideas for teachers. We believe successful career integration takes place in the classroom when educators know what they are expected to teach, and when they are given good ideas to help them teach it. The Blueprint, the career packets, and the PLAN file have been a tremendous help in ensuring that career integration actually happens. Cynthia Gahris is Supervisor of Career Development Programs, Ohio State Department of Education, Columbus, OH.. CGpnw020199 U.S. Department of Education Office of Educational Research and Improvement (OEM) National Library of Education (NLE) Educational Resources Information Center (ERIC)


Procalcitonin is the precursor of calcitonin hormone, produced by C cells of thyroid gland in physiological conditions. It is also produced in parenchymal cells of many tissues and leukocytes in pathological situations. In the normal condition, procalcitonin is converted by specific enzymes to the calcitonin. Therefore, it is amount in circulation is very low. On the contrary, it increases in the blood and tissue during diseases, because the procalcitonin produced in parenchymal cells cannot be converted to calcitonin. A great number of data has been documented about procalcitonin in human at the physiological and pathological conditions. Furthermore, productions, genetic regulation, kinetics, analysis methods, it is relation with cytokines and diseases have been studied extensively. Consequently, it is used as a reliable biomarker in human medicine, particularly for widespread bacterial infections. However, little is known about the implications in veterinary medicine. In terms of lightening the veterinary field, basic information and new findings on procalcitonin has been reviewed once more, although, quite a few studies have been conducted on procalcitonin in domestic or farm animals. The findings show that production and kinetics of procalcitonin in animals may be quite different, in both of the normal or pathologic conditions. It is not yet used as a biomarker in veterinary medicine. In addition, it has not yet been investigated whether it has an effect on reducing the antibiotics usage in animals.


The process of rationalization and liberalization dominating the government's new economic policy (NEP) is an inevitable part of India's need to exist and grow with dignity in the emerging global economy. While this implies freedom and flexibility for industry, this has also led to incidence of labour redundancy, unemployment and casualization. With the government committed to full employment in the current five-year plan and the trade unions bearing a crucial social responsibility to protect workers' interests, the industrial relations issues involved in NEP need to be resolved amicably. This paper by N R Sheth examines these issues in detail and discusses the need for a meaningful dialogue among the various concerned parties in an atmosphere of mutual trust.


Display device according to one embodiment of the present invention includes a display panel, and a polarization switch panel disposed on the display panel, wherein the polarization conversion panel is an insulating substrate, the absorption polarizer disposed on the insulating substrate, located above the absorbing polarizer a first electrode, on the first electrode is formed so as to be interposed between spaced fine space over which a protective film comprising an inlet, a cover film, the cover film so as to cover the injection hole is formed on the protective film seals the fine space It includes a position the second electrode, the liquid crystal which is located on the reflective polarizer, and the fine space that is formed on the second electrode layer.


Abstract: Careful history-taking improves diagnosis of non dental orofacial pain, a not uncommon group of conditions. Accurate diagnosis of conditions such as chronic idiopathic facial pain, temporomandibular disorders, burning mouth syndrome and trigeminal neuralgia is essential if inappropriate dental treatment is to be avoided. There are few investigations to help in the diagnostic process and many of these patients have other forms of chronic pain. All the conditions are best treated using a holistic approach. Drugs such as tricyclic antidepressants and anticonvulsants are often effective and surgery can be highly successfully in trigeminal neuralgia. Patient education is paramount.Clinical Relevance: Although the majority of pain seen in general dental practice is dental in origin, chronic non dental orofacial pain must be recognized as its management is entirely different.Dent Update 2007; 34: XXX-XXXAlthough the majority of orofacial pain which dentists encounter is of dental origin, recent studies in the UK have shown that chronic orofacial pain of non-dental origin has a prevalence of 7%, and many of these patients will have chronic pain in other parts of the body. Even trigeminal neuralgia, which has been considered to be a rare pain, has recently been shown to be more common than expected when the databases of UK GPs were examined. Patients are often unsure of the cause of their pain and decide for themselves whether or not it is of dental origin. They therefore seek what they think is appropriate care. It is therefore essential to make the correct diagnosis so that the patient may be managed in the most appropriate way.Some form of classification is useful when attempting to make a diagnosis, to facilitate treatment decisions and predict future outcome. Not only does the pain need to be classified, but its psychosocial impact must be assessed. Facial pain has been classified and diagnostic criteria proposed by both the International Society for the Study of Pain (IASP)


A medical diagnostics assembly manipulates nano-quantities of fluid. The assembly has a base plate (1) whose surface is sub-divided into zones (6, 7) whose different surface structures have different capillary characteristics. - One or more first zones have structures (6a - 6e) with regular micro- or nano-structures. The base plate and structured zones are formed from a single piece of material. Also claimed is a process to fabricate the medical diagnostics assembly by machining, laser beam cutting, exposure to an ion beam or micro injection-molding. The base plate and other structures are made from a single piece of material e.g. plastic, glass or silicon.


Medical developmental biology was a novel subject developped with every subject in life science,especially developmental biology and medical knowledge.The article discussed with the history,the relevence of the other subjects and the teaching model of medical developmental biology.And the authors hoped that they would provide some useful information for further optimization teaching of medical developmental biology.


In this article, we provide an analysis of the description of the pre-cosmic chaos and the function of this description within the context of the theory of participation which can be reconstructed in Plato's Timaeus. More specifically, we will assume that the pre-cosmic chaos represents a counterfactual situation in which the universe is conceived without the action of the intelligible. This counterfactual state will be considered as an initial sequence allowing to visualize in a quasi-spatial way how the phenomenon of participation operates. We will give a detailed analysis of the passage (52d4-53b7) in order to integrate it as a sequence of what we will call the anatomy of participation. In our study, two more questions will be examined: i) the representation of the sensible without the intelligible in Plato's works (Timaeus, Statesman, Philebus, Parmenides) and ii) the role of world soul as a possible cause of all movements in the universe (Timaeus and Laws).


In this paper, we studied on Doppler gap-filling algorithms suitable for a portable or low-cost medical ultrasound imaging system, and as a result, found out algorithms based on mirroring or autoregressive model. Moreover, controlling the computational demand in the proper range, we improved the performances of these algorithms by solving their problems. Effectiveness of these modified algorithms is verified by computer simulations and experiments which used artificially generated Doppler signals and Doppler data acquired from human body through an actual ultrasound system.


While completing a study unit on surface water, a group of 22 high-school freshmen started asking questions about local water degradation and its connection to the regulatory process. They studied new regulations currently being drafted by the Maine Department of Environmental Protection and rewrote them in what they considered everyday English. Once the regulations were clearer, the ninth graders contacted politicians and key legislators by mail, wrote a citizen's guide to wetlands protection, prepared personal testimony, and presented that testimony at a state regulatory hearing. Concerned about their credibility with the Board of Environmental Protection, the students found that they needed to have a clear understanding of the scientific information, and needed to write their opinions in a concise and persuasive manner. They learned the necessity of writing multiple drafts, paid more attention to grammatical details, and were unwilling to turn documents over to the Board if the writing was not polished...


There are several ways to measure fatness and obesity, each with its own strengths and weaknesses. The primary measure for tracking the prevalence of obesity has historically been body mass index (BMI). This paper compares long-run trends in the prevalence of obesity when obesity is defined using skinfold thickness instead of body mass index (BMI), using data from the full series of U.S. National Health Examination Surveys. The results indicate that when one uses skinfold thicknesses rather than BMI to define obesity, the rise in the prevalence of obesity is detectable ten to twenty years earlier. This underscores the importance of examining multiple measures of fatness when monitoring or otherwise studying obesity.


This chapter develops a view according to which there is a constitutive aim of intention that parallels the constitutive aim of belief, and both of these constitutive aims can be used to explain some of the rational requirements governing intentions and beliefs. The chapter first considers in what sense there is an "aim of intention." It begins by looking at many of the philosophical ideas associated with the "aim of belief," noting that some of these won't easily carry over to the "aim of intention" in the relevant way. However, if we understand constitutive aims in terms of the "job descriptions" of attitudes, there is room for optimism here. It then considers how the constitutive aims might explain certain consistency and coherence requirements, including means–ends coherence. The chapter critiques Michael Bratman's suggestions for how these explanations might go, and offers an alternative view, which it calls "Non-normative Disjunctivism."


Aiming at the problem of short life cycle and uneven energy consumption of low power adaptive clustering hierarchical protocol (LEACH), an improved LEACH algorithm is proposed. In the selection of cluster head nodes, the optimal cluster head proportion is calculated by considering the problem of residual energy and current position, and the SEP algorithm is used to calculate the different cluster head election probability for the advanced nodes and ordinary nodes, so that the distribution of the cluster heads is more uniform. At the same time, in the data transmission phase, data communication is performed using a hybrid routing method. That is, the distance from the node to the cluster head and the base station is compared. When the node is close to the base station, the node directly communicates with the base station. Otherwise, it communicates with the base station through the cluster head. It reduces the number of clustering and saves network energy consumption. Simulation experiments show that the improved LEACH algorithm makes the distribution of dead nodes more discrete, the entire network energy consumption more balanced and extends the life cycle of the wireless sensor network.


ONLY one who was very reckless would categorically describe a Beethoven letter as "unpublished": the most that anyone can safely say is that he is not aware of any previous publication. The only catalogue of Beethoven letters that the present authors know is that by Kastner,1 including 1433 entries of which some sixty or seventy are without listing of publication. In the forty years that have passed since that catalogue was prepared, a considerable number of the letters listed therein have come to their first publication, and more than 300 that Kastner did not include have been discovered.


Carl Schmitt is usually perceived as the theorist of total state, total war and total hostility. In the article, the author however tries to show that from 1937 to 1944, Schmitt was arguing that total war and total hostility were dangerous for Germany (as well as for the rest of Europe) and warned against perpetuation of all efforts to totalize enemy that started in 1914. In his theoretical endeavors in this period there was place for the total state only - and especially for the total state strong enough to resist temptation of declaring total war on total enemy. The total state he recommended Hitler and his Nazi comrades was German Reich, as a part of Europe ordered and divided in the huge spaces (Grossraumordnung). Positioned in the centre of Europe, between the rest of the powers (France, Italy, USSR as well as the Scandinavian states), Germany should be careful enough to wage war only against its Eastern enemies (Poland and maybe USSR) and only in order to achieve 'just' borders. Occupying in this way its huge space Germany should devote itself to the task of exploitation of various peoples such as Poles, Chechs and Slovaks, which were perceived as incapable of having their states and doomed to serve the master race - the Germans.


The Ruwenzori Mountain is a fault-bounded, uplifted block of Precambrian rocks situated immediately north of the equator within the western branch of the rift system of East Africa. Understanding the structure and development of the Ruwenzori Mountain may yield additional insight into the evolution of the East African rift system as a whole. During June through mid-September 1973 four portable seismographs were used in a microearthquake survey of the area around the Ruwenzori Mountain. A microearthquake reconnaissance of various districts of Uganda during the latter part of September 1973 showed the Ruwenzori region to be the most seismically active area in Uganda. In the Ruwenzori region the spatial trends of the microearthquakes are correlated with the major rift faults and volcanic zones. The seismicity is shown to extend beneath and transverse to the Ruwenzori Mountain block, where there is an indication of subcrustal seismicity (25–40 km). Elsewhere in the region studied, hypocentral depths ranged between 0 and 25 km. Composite focal mechanism solutions for events associated with the Bwamba, Ruimi-Wasa, and Nyamwamba faults show dip slip motion along steeply dipping planes. The extensional axes trend east-west. The motion tends to raise the mountain block relative to the surrounding country. A focal mechanism determined at the junction of the northern and southern Ruwenzori indicates that the northern portion is being uplifted with respect to the southern block.


Lowering compulsory speed limits is one of the available methods of energy conservation that has been tried overseas. This paper reviews world experience in this regard and investigates the implications of this experience for Queensland. It has been optimistically estimated that a reduction in the compulsory speed limit from 100 km/h to 80 km/h would reduce fuel use in transport industries by 1.2 Per cent. As this is only 0.6 Per cent of the total state petroleum usage, other measures of conservation should be investigated. Overseas experience has pointed to substantial reductions in the number of serious accidents when operating speeds have been reduced. This finding has also been investigated in this paper and a caution is sounded against assuming that a similar effect would be experienced locally. There are significant differences between the local road and traffic environment, and those existing in overseas countries before lower speed limits were introduced. These differences are such that accident rates, in general, could even possibly rise in Queensland if the compulsory speed limit were to be reduced. The severity of accidents would most likely be reduced; however, the combined effect of these two factors is very difficult to predict without further detailed study (a).


ABSTRACT: This study aims to document undergraduate students' patterns of participation in Malaysian classrooms. Interviews and observations were carried out. Around 85 students from two communication classes were observed over the period of two semesters (28 weeks). Most of the participants fell between the age of 18-19 years old (65.8%) and 66.7% of the participants were female, while 33.3% were male. Around 24 students from the two classes were interviewed. Four basic patterns of participation emerged from the data: (1) active participation, (2) selective participation, (3) minimal participation, and (4) passive participation. It was also found that students' individual participation pattern could be influenced a myriad of factors, thus making their participation patterns flexible. This research demonstrated that the participatory roles students took in class could move along the participation continuum; from the most active to the least active. Recommendations are offered to promote students' participation in the context of higher learning. Educators need to strive towards providing a more supportive, non-threatening, and open learning environment where students would feel comfortable in letting their voice be heard while knowing when to be quiet so they can reap benefits from both behaviours. KEY WORDS: Classroom participation, participation patterns, undergraduate students, open learning environment, and participative behaviours. About the Authors: Siti Maziha Mustapha is an Assistant Professor at the School of Communication and Language Studies KLIUCM (Kuala Lumpur Infrastructure University College Malaysia); and Nik Suryani Nik Abd Rahman is an Assistant Professor at the Institute of Education IIUM (International Islamic University of Malaysia). They can be reached at: email@example.com and email@example.com How to cite this article? Mustapha, Siti Maziha & Nik Suryani Nik Abd Rahman. (2011). "Classroom Participation Patterns: A Case Study of Malaysian Undergraduate Students" in EDUCARE: International Journal for Educational Studies , Vol.3(2) February, pp.145-158. Bandung, Indonesia: Minda Masagi Press owned by ASPENSI in Bandung, West Java; and FKIP UMP in Purwokerto, Central Java, ISSN 1979-7877. Chronicle of the article: Accepted (December 6, 2010); Revised (January 9, 2011); and Published (February 17, 2011).


This invention relates to a fabric softener and more particularly to a free-flowing liquid fabric softener which has an improved product stability and freeze recovery. It has long been known in the art that softening agents may be applied in the laundering process to improve the softness or hand of clothes or other textile fabrics washed thereby. These softening agents are commonly used during the rinsing of the fabrics or are applied in a separ gate bath following the ordinary rinsing step. In order to provide satisfactory softening effects to these fabric rinses it is essential that the softening agent be readily soluble or dispersible in the moderately warm or even cold water which may be used in the rinsing bath. . Moreover, it is desirable that these agents be highly ac tive and substantive to cloth when present in low concen trations in the rinsing bath. In addition, a highly active and readily dispersible product provides the housewife with ease of application and enables her to achieve maxi mum softening effects with a minimum of product. There are numerous liquid fabric softeners available today, many of which are based upon various long chain quarternary ammonium compounds as the active soften ing ingredient. Higher molecular Weight quarternary am monium compounds have been found to be particularly useful for fabric softening because they are readily ad sorbed upon the fibers of cloth from dilute aqueous dis persions. There are certain disadvantages, however, to the use of these liquid fabric softeners by the housewife and other persons engaged in the laundering process. Instability of the active ingredients of liquid softeners frequently re sults in separation of product upon standing. Moreover, certain additives such as coloring agents and perfume may also settle out during extended storage. These separation problems are particularly acute in the warmer climates where the softener product is exposed to relatively high temperatures. Another disadvantage of the usual liquid softener is the tendency of the compositions to be very viscous un less the active softening ingredients are present only in low concentrations. A viscous product that is not readily pourable causes great inconvenience to the housewife. But a dilute composition that has satisfactory pourability generally requires large unwieldy product containers in order to provide the consumer with a reasonable number of effective softening applications per container. The re tail marketing of a dilute composition having a high pro portion of water in a large product container results in the further disadvantage of high packaging and shipping COStS. The viscosity problem becomes particularly serious dur ing the winter months when the liquid products are fre quently exposed to low temperatures while in transit or in storage during the marketing process or while in the basement of the consumer. Many of the liquid products freeze or become extremely viscous at these low tempera 0


And forming a coating film 100 on the surface of the conductive parts own body 500, forming a photosensitive film 110 to the conductor 500, the coating film 100 is formed, the photosensitive film 110, the baking step and the step, and the developing of the photosensitive film (110) for developing the photosensitive film 110 is exposed to the light of exposing to light in a pattern corresponding to the concave portions and the convex portions of the pattern method of manufacturing an electronic device having a. To alleviate or prevent the metal film ll is removed more than necessary by the production method.


The development of employee expertise is described as a strategic imperative for ever-changing organizations in a hyper-competitive economic environment. However, the lack of an adequate assessment tool for expertise has hindered empirical research. This paper conceptually and empirically develops the generalized expertise measure (GEM) and examines its psychometric properties in two managerial samples. Schwab's (1980) three stages of measure development process are followed. The factor structure of the measure is then examined employing exploratory factor analysis (EFA) procedures and confirmed using confirmatory factor analysis (CFA) on independent samples. The results are presented and a preliminary measure of expertise is provided.


Background: Spontaneous cerebellar hemorrhage (SCH) is a potentially life-threatening condition that results in early neurological deterioration, significant disability, and adverse consequences. Therefore, knowledge of the factors that potentially affect the outcome is crucial for a sound clinical decision-making framework and implementing efficient therapeutic measures. Objectives: This study aimed to identify possible clinical, radiological, and therapeutic factors associated with 30-day outcomes in patients with acute SCH. Methods: Sixty-six computerized tomography (CT) diagnosed cases of SCH above 18 years of age who were admitted and managed in the Department of Neurosurgery of Chittagong Medical College Hospital from October 2021 to September 2022 were enrolled prospectively in this study based on inclusion and exclusion criteria. Data regarding demographic, clinical, radiographic, and treatment modalities was recorded. The 30-day outcome was assessed by the Glasgow Outcome Scale (GOS) score and analyzed. A poor outcome was defined by GOS ≤3. Results: The mean age was 65.6±10.8 years and 56.1% were male. The median Glasgow Coma Scale (GCS) score on admission was 13 [interquartile range (IQR) = 8-14]. Twenty-five patients (37.9%) underwent surgical management [evacuation of the cerebellar hemorrhage and placement of an external ventricular drain (EVD) in 7 (28%); EVD alone in 12 (48%), and only evacuation in 6 (24%) cases of surgically managed] and 41 (62.1%) were treated conservatively. The 30 day mortality rate was 36.4%. Regarding 30-day outcomes, 47% (31) of patients had a poor outcome after 30 days. On univariate analysis, GCS score on admission, hematoma size, hematoma volume, ventricular extension, 4th ventricle obstruction, hydrocephalus, tight posterior fossa, ratio between transverse diameter of cerebellar hematoma and posterior fossa, intervention type, and need for mechanical ventilation were significantly associated with 30-day poor outcome. .....


The global behavior of solutions for a Cooperative model with stage-structure. The local asymptotic stability and the global asymptotic stability of the positive equilibrium point are given by linearization and Lyapunov function respectively.


Kathleen McInnis-Dittrich: Social Work with Older Adults:A Biopsychosocial Approach to Assesment and Intevention – Third Edition(Allyn and Bacon, Boston, 2009 – Pearson Education Inc.)


In social relationships practice, the way work is contracted takes various forms. One of them is given by the management contract in a company with limited liability. The definition of this contract and its precise identification attract incidence or not, as we shall see in the paper presented, of protection limits offered by labour law. In this context, the paper aims to describe the identification of management contract in relation to individual employment contract to outline the legal nature of this contract, the legal framework applicable and how can it be distinguished from the employment contract. In the analysis performed in the absence of express provision I started from a series of analogies and deductions in order to provide the management contract a self-contained character in relation to the individual employment contract, however respecting the desire of protecting rendered work.


The authors provide details of the existing equipment and capacity of the marshalling yards in the Lyons area, as well as of the reasons for the construction of a new marshalling yard, and the choice of Sibelin. They then show the lay-out of this marshalling yard, which will comprise 1 set of 14 reception sidings, 1 set of 44 marshalling sidings, each having a length of 900 metres, 1 set of 12 departure sidings, 2 sets of 4 relay sidings, and 2 separate humps, having a daily capacity exceeding 4,000 wagons. They describe the earthwork operations, as well as the principal structures, the signalling equipment, the signal cabins, the electric traction and telecommunication installations, the yards for the adjustment of loads, and the inspection and repair of rolling stock, and a number of new devices to be used to facilitate marshalling operations.


We construct error-correcting codes over permutations under the infinity-metric, which are also Gray codes in the context of rank modulation, i.e., are generated as simple circuits in the rotator graph. These errors model limited-magnitude or spike errors, for which only single-error-detecting Gray codes are currently known. Surprisingly, the error-correcting codes we construct achieve a better asymptotic rate than that of presently known constructions not having the Gray property, and exceed the Gilbert-Varshamov bound. Additionally, we present efficient ranking and unranking procedures, as well as a decoding procedure that runs in linear time. Finally, we also apply our methods to solve an outstanding issue with error-detecting rank-modulation Gray codes (also known in this context as snake-in-the-box codes) under a different metric, the Kendall <inline-formula> <tex-math notation="LaTeX">$\tau $ </tex-math></inline-formula>-metric, in the group of permutations over an even number of elements <inline-formula> <tex-math notation="LaTeX">$S_{2n}$ </tex-math></inline-formula>, where we provide asymptotically optimal codes.


The potential flow over the hulls of six ships has been calculated using the computer program of Dr. S.B.S. Uberoi. On the basis of these calculations and of three-dimensional potential flow and potential wake calculations made previously by the author, an analysis has been made of the influence of the form of sections on the potential wake. An estimate of the frictional wake was carried out based on the flow pattern over the hulls, the lengths of the streamlines and the results of model tests.


In the continuous time-Merton-model the instantaneous stock proportions are inversely proportional to the investor's local relative risk aversion γ. This paper analyses the conditions under which a HARA-investor can use this 1/γ-rule to approximate her optimal portfolio in a finite time setting without material effects on the certainty equivalent of the portfolio payoff. The approximation is of high quality if approximate arbitrage opportunities do not exist and if the investor's relative risk aversion is higher than that used for deriving the approximation portfolio. Otherwise, the approximation quality may be bad.


chapter 1 Introduction chapter 2 Tagal Power Relationships chapter 3 The Supernatural and Power chapter 4 The Church and Power chapter 5 Bridewealth, Status, and Power chapter 6 Leadership and Power chapter 7 Social Identity and Power chapter 8 Conversion, Identity, and Power chapter 9 Bibliography chapter 10 Index


Long term storage of R. solani was improved by using the freezing and thawing conditions that are generally used for animal/human cell lines. Key factors to success were the use of controlled freezing and the use of complete mycelial colonies. Authors Jaap Keijer, Petra M. Houterman, Annette M. Dullemans, and Marja G. Korsman This regular paper is available in Fungal Genetics Reports: https://newprairiepress.org/fgr/vol43/iss1/12 Long Term Storage of Isolates of Rhizoctonia Solani, a Mycelial Fungus Jaap Keijer, Petra M. Houterman, Annette M. Dullemans, Marja G. Korsman Department of Virulence and Resistance, DLO-Research Institute for Plant Protection (IPO-DLO), P.O. Box 9060, 6700 GW Wageningen, The Netherlands and Department of Microbiology and Biotechnology, DLO-State Institute for Quality control of Agicultural Products (RIKILT-DLO), P.O. Box 230, 6700 AE Wageningen, The Netherlands. Long term storage of R. solani was improved by using the freezing and thawing conditions that are generally used for animal/human cell lines. Key factors to success were the use of controlled freezing and the use of complete mycelial colonies. The soil-borne plant pathogenic fungus Rhizoctonia solani is highly diverse and variable. For research purposes it is necessary to prevent genetic variability and to be able to maintain isolates for a long period of time in their original condition. Since R. solani does not make vegetative spores, these cannot be used for storage, which is usually done by maintenance at 4 C on e.g., Mouth-Pepton-Agar (MPA; Oxoid) or Potato-Dextrose-Agar (PDA; Difco) plates with periodical transfer to new plates. This method of storage is unsuitable for molecular studies since the isolates grow and may change and, furthermore, plates may become contaminated, dry out, etc. Alternative methods like dry storage on soil or soil-bran mixtures have been published (e.g., Butler EE (1980) Phytopathology 70:820-821), but work unsuccessfully in our hands. A significant percentage of isolates could not be recovered. In addition, we encountered contamination. Alternatively, isolates may be stored in liquid nitrogen in the presence of cryoprotectants. Storage at low temperatures is the method of choice for long term preservation of biological material and this option was therefore pursued.


Today, our country is in difficult financial conditions, we can call it crisis, which provoked by coronavirus and hostilities. Industry enterprises are the driving force of the economy and constitutes a large percentage of it, providing stability and high profits for the state budget, which is necessary to the national economy now. Therefore, in order to ensure the stable, uninterrupted work of industrial enterprises in crisis situations, in conditions of limited resources, to enable enterprises to modernize their equipment, maintain the continuity of operational processes, stimulate innovative developments, the enterprise needs to attract additional financial benefits, which are best realized in the form of investments, which allows benefit from them in the future. A comprehensive, multi-faceted, investment strategy must be developed and implemented in order to be able to best attract investment and make the most of it. The article raises the issue of development of investment activity of an industrial enterprise and its introduction as an element of strategic stability, taking into account the peculiarities of the industry. The scientific and methodological basis, works and opinions of scientists have been investigated and considered, and an alternative definition of the concept of «investment strategy» is formed. The development of industry enterprises is extremely dependent on the investment attracted, because they are a building raw material and an element of strategic stability. The main factors that have a significant impact on the process of creating and implementing it at the enterprise have been developed to create a competitive investment strategy. The main directions of investment activity at industrial enterprises, which should provide the enterprise with strategic stability and continuous work in the future have been developed too. Currently, the formation of an investment strategy at enterprises is limited, and has many obstacles on its way to implementation, both at the state level and because of incompetence on the ground. But it allows the enterprise to become stronger and more independent of external conditions. In the future, with the development of the investment market of Ukraine, and its integration into a more developed European economy, this issue will become new features and colours.


Background: In the Brazilian Public healthcare system (The Unified Healthcare System - Sistema Único de Saúde), Primary Healthcare has expanded from implementing healthcare networks, an organization form of services with centrality to primary care services. Due to the extension and heterogeneity of Brazilian municipalities, several organization forms of primary care services existed. In the city of São Paulo they were organized by three modalities of Basic Health Units. Thus, this study aimed to evaluate the care continuity in high-risk pregnancy care in different models of the basic health units. Methods:Data analysis defined performing prenatal care in primary care even after referral to the high-risk pregnancy service as the dependent variable. The independent variables were the sociodemographic and organizational aspects of health services. Logistic regression was used as the statistical technique. Results:Care is provided in a similar way in all basic health unit models, without prioritizing pregnant women with greater vulnerabilities (under 15 years and over 35 years, with education less than 7 years). Regarding women of black or brown color, it was observed that they were more likely (OR 1.997) to have care continuity in family health units. Home visiting and knowing the community health agent proved to be tools for organizing health services which are capable of producing better care. Conclusion: Primary healthcare services in Brazil for high-risk pregnancy care are organized without considering individual vulnerabilities. The home visits and the presence of the community health agent need to be strengthened in organizing the services, as they are able to modify the process of producing healthcare.


The utility model relates to a shaftless rotary type kitchen waste biochemical processor. The shaftless rotary type kitchen waste biochemical processor comprises a rotatable bin body which is driven to rotate through a motor and a speed reducer, the bin body is composed of an outer layer and a liner layer, and the liner layer is provided with a spiral blade. The front end of the bin body is provided with a rotary joint capable of relatively rotating around the axis of the bin body, the rotary joint is provided with a hopper, a feeding trough is arranged on the lower portion of the hopper, and a discharging trough is arranged on the lower portion of the feeding trough. The rear end of the bin body is provided with a swivel joint capable of relatively rotating around the axis of the bin body, and the swivel joint is provided with a steam/water feeding tube, a steam/water return tube, an air intake tube and an air exhaust tube. A shaftless rotary type bin body structure is adopted for the shaftless rotary type kitchen waste biochemical processor, so that materials in a bin are stirred, the processing quantity is large, needed driving power is small, efficiency is high, energy is saved efficiently, and when the bin body rotates, the rotary joint and the swivel joint can guarantee normal feeding, discharging, air intake, air exhaust, steam/water feeding, steam/water return and output of measurement data.


The present invention discloses a pattern recognition method and system for detection and control of applications for implementing a user network user correctly perform detection on application visited access scenario. When the present invention is to create a session S9, visited policy control and charging rules function entity V-PCRF notifies home policy control and charging rules function entity which supports the H-PCRF reports the requesting application or non-application detection control function requesting application reports ADC ADC function; H-PCRF determined according to V-PCRF function mode is supported by the ADC ADC rules to provide V-PCRF. By the present invention can be in the visited access scenario, H-PCRF to achieve correct distinction between the VPLMN ADC mode, thereby performing correct decision and ADC functions.


Evaluating retrieval systems, such as those submitted to the annual TREC competition, usually requires a large number of documents to be read and judged for relevance to query topics. Test collections are far too big to be exhaustively judged, so only a subset of documents is selected to form the judgment \pool." The selection method that TREC uses produces pools that are still quite large. Research has indicated that it is possible to rank the retrieval systems correctly using substantially smaller pools. This paper introduces an active learning algorithm whose goal is to reach the correct rankings using the smallest possible number of relevance judgments. It adds one document to the pool at a time, always trying to select the document with the highest information gain. Several variants of this algorithm are described, each with improvements on the one before. Results from experiments are included for comparison with the traditional TREC pooling method. The best version of the algorithm reliably outperforms the traditional method, although its degree of improvement varies.


A microspot electron gun employing cold cathode emission from a glow discharge is described. The gun works in soft vacuum at currents of a few milliamps and voltages up to 40 kV. Measurements on beam characteristics were made and the effect of various operating parameters investigated. The cathode emission was found to be peaked at the centre with a brightness of the order of 105 A cm-2 sterad-1. Machining trials were made on stainless steel and silica. It is concluded that this type of gun could be developed further to about a factor 10 increase in brightness.


Th e use of non-steroidal anti-infl ammatory drugs as a fi rst-line treatment for spondylarthritis, as well as their eff ect on the x-ray progression of sacroiliitis and spondylitis is justifi ed. Presented data on high anti-infl ammatory effi cacy and good tolerability of nimesulide in patients with Spa.


A novel procedure to perform a membrane-inlet mass spectrometry experiment is presented, which allows semi-volatile organic compounds to be preconcentrated inside the membrane, before they are thermally released into the ion source. The method uses a standard membrane inlet with a tubular silicone membrane passing straight through the ion source of the mass spectrometer. A long slit in the ion source parallel to the membrane allows electrons from the filament to continuously bombard the membrane surface. The membrane is kept cold by a continuous flow of water or sample solution passing through the inlet. However, during a short interruption of the flow, the membrane is rapidly heated by the electron bombardment and organic compounds dissolved in the membrane are thermally released into the ion source. In this fashion a desorption peak is obtained. Using the areas of the desorption peaks, we have been able to detect semi-volatile, hydrophobic organic compounds (boiling points above 200 °C) in aqueous solution at low and sub parts-per-billion levels. In general, the detection limits were 10–100 times lower than previously published results, where membrane-inlet mass spectrometry has been used for the detection of the same compounds. Good linearity over 3 orders of magnitude was obtained and the standard deviation was 5%.


The article aims to objective identify the new industrial profile of Parana and spatial trends of investments and the specialty of the new investment and the regions that receive greater incentives. The discussion about the value of industrial transformation, attracting industries to the regions, through tax incentives offered by the State Government of Parana, were instrumental in leveraging industry in the state, including the internalization of this sector, arising from these points the protocols investment plans of the industries installed. In the text works with theories related to Economic and Industrial Geography because they help to clarify the contribution of the impacts of industrialization in regional development. This work is based on secondary data collected for this thesis and several related theoretical frameworks. In this research article references were used in books, articles, dissertations, theses and secondary data. The preliminary results portray the characterization of the new industrial profile and the spatiality of this segment of the industry and their respective investments.


The global analysis method takes the consistency examination,matrix improvement and weights ranking as an integral process.The genetic algorithm was adopted to optimize the consistency index coefficient function,and the niche technique was also used to find the optimum solution when there were many pre-optimized parameters.The time complexity and stability of the algorithm were analyzed.Comparisons of simulations show that the algorithm can make judgment matrixes have smaller consistency index coefficients,which is on the basis of correcting the initial judgment matrixes in fewer degrees.The method was proved to be feasible by an example analysis and an application in electromagnetic compatibility evaluations of ship electric propulsion systems.This method is valuable in overcoming the one-sidedness of evaluating complex systems.


The two books reviewed in this article engage with 'participatory art', in which artists mobilise people as the central medium of their work. Grant Kester argues that such works have the potential to generate new communal forms that challenge neoliberal hegemony, while Claire Bishop argues that in dispensing with the negating praxis of the avant-garde they all too frequently end up reproducing its logics. The article suggests that if the binary that structures both their arguments is overcome, a productive synthesis of their arguments can be made – although this still leaves unanswered a number of questions about the role that art might play in social change. Bishop, C. (2012) Artificial Hells: Participatory Art and the Politics of Spectatorship. London: Verso. Kester, G. H. (2011) The One and the Many: Contemporary Collaborative Art in a Global Context. Durham, NC: Duke University Press.


Objective:To study the sexual and urinary functions in male patients after radical resection with pelvic autonomic nerve preservation for rectal cancer. Methods: We performed a standard questionnaire using the International Index of Erectile Function before and after pelvic autonomic nerve preservation surgery in 53 males with rectal cancer compared with traditional surgery in48 males. Results: In TME +PANP and TME groups,the incidence of erectile dysfunction was 28.30% and 72.92% ; the incidence of ejaculation disorder was 24.53 % and 61.67% ; the incidence of urination dysfunction was 18.87% and 48.33% .The significant differences were doserved between the two groups (P0.01). Conclusion:The radical operation with PANP for rectal cancer can enhance sexual and urination functions and improve patients post-operation quality of life.


Construction law on bankruptcy of a bank that is in Bankruptcy Act fully authorizes Bank Indonesia to file for bankruptcy on a bank is not in line with the stages and processes in general insolvency giving sovereignty to the creditor on the basis of the relationship existing debts in making Commercial debtors in bankruptcy court. Results of research conducted in the field Showed that the position of Bank Indonesia as the banking authorities as the only party that can file for bankruptcy on a bank is not in accordance with the principles of the general bankruptcy protection for the rights and interests of creditors. BI Position as the only party authorized to make insolvent banks Because if the bank can Easily be filed by any creditor bankruptcy then the risk is very high, Because of the simple setting of the bank's bankruptcy would result in public confidence in the bank could be lost.


The prevalence of massive dolomites in the ancient rock record cannot be reconciled with their striking absence from modern environments. This irregularity is compounded by the experimental difficulties in synthesizing primary dolomite (precipitation of the mineral phase directly from aqueous solution) at low–temperatures (less than 50°C). These difficulties have been attributed to reduced reaction kinetics by inhibitors including low Mg:Ca ratio, ion complexing, hydration spheres and the formation of neutral complexes with sulfate (e.g., Baker and Kastner, 1981; Hardie, 1987; Zhong and Mucci, 1989).


BACKGROUND: GIST is a visceral sarcoma that arises from the gastrointestinal tract. Computed tomography (CT) is an imaging modality of choice for diagnosing GIST. The clinical features and radiologic differential diagnosis of gastrointestinal stromal tumours are discussed by evaluating CT features of GIST in 40 cases. METHODS & MATERIALS: In this study, 40 biopsy proven cases of GIST attending our department from November 2010 to July 2012 are evaluated retrospectively. The CT scan was performed prior to the treatment in all these patients. CT imaging features that were taken into account include tumour location, size/diameter, degree & pattern of enhancement, intraluminal/exophytic, internal necrosis & haemorrhage, perilesional fat stranding, local spread, nodal & distant metastasis. RESULTS: In 26 out of 40 cases (65%), tumour was found in stomach, 8/40 (20%) in small bowel (jejunum & ileum), 4/40 (10%) in omentum and mesentery; and 2 (5%) tumour was found in transverse colon. 28/40 (70%) had exophytic tumour with communication to lumen of gastrointestinal tract or in omentum and mesentery; rest 12/40 (30%) had polypoidal mass. Size of tumour ranged from 4 to 15 cm, with mean of 7.9 cm. 30/40 (75%) cases showed heterogeneous enhancement with necrosis and/or calcification, rest 10/40 (25%) had homogenous enhancement. The CT HU ranged from 35 to 55, with mean of 40. 28/40 (75 %) cases had well defined margins of tumour, and rest 12 (30%) cases showed perilesional fat stranding and loss of fat plane with adjacent organ. 4/40 (10%) cases showed regional nodal involvement and 6/40 (15%) cases shows distant metastasis to liver & lungs. CONCLUSIONS: The stomach was the commonest site of GIST occurrence among our patients. The CT features of GIST were exophytic, ulcerated mass with well-defined tumour margins, and heterogeneous enhancement on post-contrast


An existence of predominant symmetrical spin configuration (spin polarised phase) and "diluted" density of states (pseudo-gap) in a layer under the Fermi level in a quantum wire is predicted. The condition of cross-over from non-polarised phase to polarised one was derived. The transition occurs for sufficiently low electron density in a wire and is accompanied by an acute decrease of electron density of states near the Fermi level.It may result in a corresponding decrease of conductance. A similar effect may exist in a two-dimensional electron gas. and experimental investigation of systems: quantum many properties we concentrate strong correlation in quantum (QWRs). very effects can drastically change the properties of electron respect


PRESENTS A CHEMICAL COMPOUND OF FORMULA (I) and pharmacologically acceptable salts thereof, wherein Y is C SUB {24}; X is a valence bond or alkylene C SUB {1-6}; R2 is an aryl substituted or unsubstituted (EG phenyl and naphthyl.) Or heteroaryl (EG thienyl and furyl.); R2 is hydrogen or aryl C SUB {1-6}; R3 is hydrogen, OR SIMILAR HYDROXIDE; R4 is benzyl substituted or unsubstituted OR OTHERWISE. EXAMPLES Typical are (2S *, 3S *, 4S *, 5S *) - 4-carboxide-3- [N- (5-ISOPROPYL-2METOXIDO-BENZYL) AMINO] -5-METHYL-2-phenylpyrrolidine and (2S * , 3S *, 5S *) - 5-CARBOXIDO.3- [N- (2METOXIDO.5.TRIFLUOROMETOXIBENCILO) amino] -2-phenylpiperidine. NEW ACIDS azaheterocyclecarboxylic SUBSTITUTED of the invention have excellent activity antagonistic OF THE SUBSTANCE PY THEREFORE ARE USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISEASES, CENTRAL NERVOUS SYSTEM, ALLERGIES, inflammatory diseases, asthma, pain or migraine in MAMMALS, ESPECIALLY IN HUMANS.


In this work, two effective and low-cost spectrophotometric methods (A and B) for the determination of lisinopril are proposed in its pure and pharmaceutical preparations. The both methods depend on the charge-transfer reaction between lisinopril as n-electron donor with 2,3- dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) in methanol medium and 7,7,8,8-tetracyanoquinodimethane (TCNQ) ) in methanol-acetonitrile medium as p-acceptor to give a colored complex, which absorb maximally at 475 nm and 740 nm respectively. These reactions were accelerated by irradiating the reaction mixtures with microwave energy (1100 W) during 45 seconds in method A and two minutes in method B. Beer's law is obeyed in the concentration ranges 0.5-60 μ mg/mL with molar absorptivity of 1.2 × 105 L mole-1 cm-1 and 0.5-15 μ mg/mL with molar absorptivity of 8.3 × 104 L mole-1 cm-1 respectively. The optimal reaction conditions values such as reagent concentration, heating time and stability of the reaction product were determined. The analytical results obtained by applying the proposed method compare very favorably with those given by the British Pharmacopoeia standard procedure.


There have been few studies of citizenship as an identity. This article explores citizenship as an identity among British Pakistanis in Bradford after the 'riot' in 2001, using qualitative data. The 2001 'riots', the political successes of the British National Party and the events after September 11 pushed British-Pakistani Muslims into the forefront of national political conflicts around citizenship, national identity and allegiance to the state. Through the analysis of interviews with both first- and second-generation British Pakistanis we examine how citizenship as a mode of identity is contextualized by them in relation to national identity, Islam and ethnicity. We identify the two generations' different 'citizenship identities'. The second generation have a strong British identity as 'British citizens' with the 'natural rights' of a British-born citizen. In contrast the first-generation migrants from Pakistan express identities as 'denizens', living but not belonging in a foreign country, who remain because their children are now 'British'.


Community-associated (also referred to as communityacquired or community onset) methicillin-resistant Staphylococcus aureus (CA-MRSA) has emerged as a significant and common cause of community skin infections over the past few years [1–3]. CA-MRSA strains are distinct from hospital-acquired strains from an epidemiological, genotypic, and phenotypic perspective [4–6]. They tend to be less resistant to antimicrobial agents than hospital-acquired methicillin-resistant Staphylococcus aureus (MRSA) strains, and almost always contain a novel type IV Staphylococcus cassette chromosome (SCC) mec gene. In addition, many of these strains have been found to contain the gene for Panton–Valentine leukocidin, a toxin that has been associated with clinical features of serious disease.


We propose the use of cloud-computing platforms and virtual network laboratories such as GENI (Global Environment for Network Innovations), together with high-speed software defined networks such as Internet2 to combat various cyber-physical implementation challenges for wide-area control of large power systems using Synchrophasors. Experimental results from a cloud-in-the-loop testbed environment are reported to support our proposed architecture.


The study of new patient record (PR) models, advanced enough to help caregivers producing and updating clinical texts, can significantly contribute to improve health care. Such innovative concepts, leading toward the realisation of the active PR, can be extended up to reduce in many instances the physician-patient gap. In this framework the authors' study tackles a basic question of the above process, that is the standardisation of medical language as used in generating a PR. The extent of the problem suggested the authors to start studying a specific section of the PR, the Holter monitoring data, possibly to be used as a paradigm of the whole PR. A controlled medical vocabulary (UMLS) drives the construction of an entity-relationship (ER) diagram, needed to determine the set of Holter monitoring data and the relationships among them. Performance evaluation shows that this approach reliably mimics meaningful clinical statements.


The synthesis and properties of some new water-soluble non-ionic triarylbismuthanes are described. o-, m- and p-Tris(methoxymethoxyphenyl)bismuthanes 1a–c are prepared from BiCl3 and the corresponding organolithium or Grignard reagents. Oxidative chlorination of 1a–c with SO2Cl2 affords tris(methoxymethoxyphenyl)bismuth dichlorides 2a–c, which are deprotected by aqueous HCl to give tris(hydroxyphenyl)bismuth dichlorides 3a–c. Treatment of tris(3-hydroxyphenyl)bismuth dichloride 3b with NH2NH2 yields tris(3-hydroxyphenyl)bismuthane 5, which dissolves in dilute aqueous NaOH. N,N-Bis(2-tert-butyldimethylsiloxyethyl)benzenesulfonamide, prepared from benzenesulfonyl chloride and silyl-protected diethanolamine, is ortho-lithiated and reacted with ⅓ equiv. of BiCl3 to give Ar3Bi 9a {Ar = 2-[N,N-bis(2-tert-butyldimethylsiloxyethyl)sulfamoyl]phenyl}. m-Phenylene-bridged Bi2- and Bi3-polybismuthanes 12 and 13 are prepared by the reaction between ortho-lithiated 9a and Ar2BiI 10. Desilylation of 9a, 12 and 13 by Bu4NF or p-TsOH·H2O in EtOH leads to the corresponding bismuthanepolyols 11, 14 and 15. The reaction between benzene-1,3-disulfonamide 16 bearing the silyl-protected bis(2-hydroxyethyl)amino side chains and ⅓ equiv. of BiCl3 affords tris{2,4-bis[N,N-bis(2-tert-butyldimethylsiloxyethyl)sulfamoyl]phenyl}bismuthane 17, which is deprotected by p-TsOH·H2O to yield tris{2,4-bis[N,N-bis(2-hydroxyethyl)sulfamoyl]phenyl}bismuthane 18. Compounds 11, 14 and 15 are only slightly soluble in water, but compound 18 is fairly soluble.


Lung microbiota predicts outcomes in critically ill mechanically ventilated patients. Lung microbiota predicts outcomes in critically ill mechanically ventilated patients.


The disposable pull-on garment (10) includes an outer surface, an inner surface, a front portion (11), rear (12), the crotch (13), the front portion (11) and a rear (12) sides each having a band (14) and overlapping side seams (15) of the side panels, the overlapping side seams the front and rear side panels joined together to form the leg openings (16) and a waist region, wherein at least one flank (17) located outside of each side panel sides (14) forming the outermost portion of the overlapping side seams (15).


To determine the prognostic factors and to rationalize adjuvant therapy, the clinicopathologic data of patients with a stage II colon cancer were analyzed retrospectively.


The properties of the Lucas-Kanade detector in motion tracking have been analysed considering the influence of typical signal forms, sampling methods and frequency domain filtering on the accuracy and computation time. Based on the investigation a simple convolution filter has been elaborated which is able to balance low and high frequency information in the images in a single step.


ABSTRACT Multisystem Langerhans cell histiocytosis (MS-LCH) is associated with high mortality when patients have risk organ involvement (RO+) or age 80%) rapid response, RO+ patients not responding (ii)within 6 weeks had highest mortality, and (iii) importantly, the more intensive Arm B reduced mortality in RO+ patients (relative hazard rate, accounting for differences in risk organ involvement, of 0.54; 95%CI=0.29-1.00). Finally, comparison of RO+ patients in LCH-I and LCH-II confirmed that increasing treatment intensity increased rapid responses (from 43%, Arm A LCH-I, to 68%, Arm B LCH-II; p=0.027) and reduced mortality (from 44%, Arm A LCH-I, to 27%, Arm B, LCH-II; p=0.042). We conclude that intensified treatment significantly increases rapid response and reduces mortality in risk MS-LCH. This trial was registered at