INTRODUCTIONIndia has the world's highest prevalence of iron deficiency anaemia among women, with 60 to 70 percent of the adolescent girls being anaemic. Adolescence is considered as a nutritionally critical period of life Objectives-1.To know prevalence of anaemia among adolescent girls 2.To study association of socio demographic charcterstics in relation to anaemia Material methods-Cross sectional study was conducted in rural area which is field practice area of dept of community medicine, Shri B.M.Patil medical college ,Bijapur. Results Significant association was found between prevalence of anaemia with type of family, socio economic status, and mother education. ConclusionA high prevalence of anaemia was found among the adolescent girls Introduction The word adolescence is derived from the Latin word, 'adolescence'; meaning "to grow, to mature" 1. The WHO has defined adolescence as the age period between 10 to 19 years of age . There are about 1.2 billion adolescents in the world, which is equal to 1/5th of the world's population and their numbers are increasing. Out of these, 5 million adolescents are living in developing countries. India's population has reached the 1 billion mark, out of which 21% are adolescents. Anemia is widely prevalent in India, developing country and affects both sexes and all age groups. Among adolescents, girls constitute a vulnerable group particularly in developing countries. In a family with limited resources, the female child is more likely to be neglected 2 Adolescent girls are at a high risk for anaemia and malnutrition. Inadequate nutrition during adolescence can have serious consequences throughout the reproductive years of life and beyond . Very often, in India, girls get married and pregnant even before the growth period is over, thus doubling the risk for anaemia 3 .During this period of adolescents blood volume and muscle mass increases and this in turn is found to increase the need for hemoglobin formation4 .The risk of iron deficiency among girls remains during her reproductive life and is the most widespread form of malnutrition among women and children Prevalence of anaemia also depends on socio economic status, literary status of mothers and type of families .Intestinal infestations are particularly important in adolescence as they cause or aggravate malnutrition including iron deficiency anaemia. The present study was planned to highlight the problem of anaemia in adolescent girls in the light of scarcely available literature for this high risk. Material and methods : The data for the present study has been collected from shivangi which is rural field practice area of Department of Preventive and Social Medicine,Shri B.M.Patil medical college,Bijapur . Calculated sample size was 400 based on the knowledge that about 50% of adolescent girls are anameic with 10% allowable error within 95% confidence limits. Data was collected during the period of November 2006 to Feb 2007, house to house visit was done . The exact date of births was collected from the birth certificate and school records. The doubtful cases were excluded from the present sample. Detailed information was collected on predesigned and pre tested proforma about socio-demographic characteristics for anemia by oral questionnaire method supplemented by physical examination, hemoglobin estimation and stool examination. Hemoglobin estimation was done using Sahil's haemogobinometer method. Anemia was diagnosed according to WHO guidelines (Demayer, 1989)5. Informed consent of the local community leaders and adolescent has been obtained before taking the sample . Results : Among the 400 adolscent girls 285 ( 68.7% )adolescent girls were found to be anaemic. The prevalence of mild, moderate and severe anaemia among adolescent girls was 44%, 25% and 2 % respectively. Socio demographic factors which were found to be significantly associated with anaemia in adolescent girls. Prevalence of anemia was significantly higher among adolescent girls belonging to joint family than those belonging to nuclear family (p<0.01) Education of mothers of adolescent girls is significant associated with prevalence of anaemia ,significantly higher in those adole sent girls having illiterate ( 57%) and just literate mother (43% ) as compared to better literate mother ( P<0.01) Percentage prevalence of anemia was highest among adolescent girls of socio economic class V and significantly re-


In the calculation of the interaction of radiation from a point source with a body (or conversely, the intensity of radiation from an emitting body at a point in space), a somewhat complex exponential integral must be evaluated. If the interaction in the body is small, however, the integral may be approximated by I=∫V dv/R2, where V is the volume of the body and R is the distance from the point to the volume element dv in the body. This integral is discussed and applied to the case of a cylindrical body. Extensive tables (>12 000 entries) and formulas have been prepared which will enable the reader to determine the value of this integral for a cylinder of any size and any point in space. A discussion of non‐negligible absorption and multiple interactions is also included.


In this paper, the electronic structure and stability of the intrinsic, B-, N-, Si-, S-doped graphene are studied based on first-principles calculations of density functional theory. Firstly, the intrinsic, B-, N-, Si-, S-doped graphene structures are optimized, and then the forming energy, band structure, density of states, differential charge density are analyzed and calculated. The results show that B- and Si-doped systems are p-type doping, while N is n-type doping. By comparing the forming energy, it is found that N atoms are more easily doped in graphene. In addition, for B-, N-, Si-doped systems, it is found that the doping atoms will open the band gap, leading to a great change in the band structure of the doping system. Finally, we systematically study the optical properties of the different configurations. By comparison, it is found that the order of light sensitivity in the visible region is as follows: S-doped> Si-doped> pure > B-doped > N-doped. Our results will provide theoretical guidance for the stability and electronic structure of non-metallic doped graphene.


Abstract A new polycrystalline layered ceramic oxide, LiFeVO4, has been prepared by a standard solid state reaction technique. The preparation conditions were optimised using thermogravimmetric analysis (TGA) technique. Material formation under the reported conditions was confirmed by X-ray diffraction studies. A preliminary structural analysis indicated that the crystal structure was orthorhombic with lattice parameters: a=4·3368 Å, b=13·1119 Å and c=16·3426 Å. The phase morphology and surface property were studied by scanning electron microscopy. Complex impedance analysis of the sample indicated bulk contribution to electrical properties at T≤125°C, grain boundary effects at the temperatures ≥125°C, negative temperature coefficient of resistance (NTCR) effect and evidence of temperature dependent electrical relaxation phenomena in the sample. The dc conductivity σdc shows typical Arrhenius behaviour when observed as a function of temperature. The activation energy value was estimated to be 0·24 eV. The value of σdc, evaluated from complex impedance spectrum, shows a jump of nearly two orders of magnitude at higher temperature (∼1·24 × 10−5 S cm−1 at 350°C) when compared with that of σdc (1·14 × 10−6 S cm−1 at 50°C). Alternating current conductivity spectrum obeys Jonscher's universal power law. The results of σac v. temperature are also discussed.


Diphenylketene reacted with the 2-azabicyclo[2.2.1]hept-5-enes 5, 6 and 10 by attack on nitrogen to give the piperidones 7, 8 and the cyclopentenols 11 respectively. The same ketene reacted with the cyclohexa-1,3-dienes 16 and 17 to give significant amounts of the [4 + 2] addition products 20 and 21 respectively. The initially formed product from the cycloaddition of the enol ether 23 and diphenylketene is unstable, rearranging to produce the unsaturated ester 24.


505 Background: Complete resection followed by adjuvant chemotherapy is standard of care for patients with localized cholangiocarcinoma (CC) or gallbladder cancer (GBC) but is not always feasible and recurrence rates remain high. Understanding the exact proportions and reasons for treatment failure is important to design new approaches, data regarding this information remain scarce. Methods: We performed a retrospective population-based review of patients with GBC or CC (intrahepatic (ICC) or extrahepatic (ECC)) resected between 2005-2019 using the BC Cancer provincial database. Chart review was conducted to characterize demographics, treatments and outcomes. Results: 594 patients were identified of whom 416 (70%) had disease recurrence. Baseline characteristics and treatments received are shown in the table. Most GBCs (96%) were diagnosed incidentally. Repeat oncologic resection was performed for 55% of these, the most common reason for not proceeding was interval disease progression between initial cholecystectomy and planned re-resection (24%). Adjuvant chemotherapy was received by 51% of 163 patients after 2017 and consisted of capecitabine (86%), gemcitabine (4%), cisplatin and gemcitabine (5%) or chemoradiation (4%). Common reasons for not receiving adjuvant therapy were post op complications or comorbidities (18 and 24%), progression (17%) and patient's preference (17%). Of those receiving adjuvant therapy, 31% did not complete all planned cycles due to progression (45%) or intolerance (55%). Median overall survival (OS) after resection was 31.6 and 18.0 months respectively for R0 and R1 resection (HR 0.43, 95% CI 0.35-0.53), 29.4 and 19.0 months with and without reresection for GBC (HR 0.55, 95% CI 0.41-0.73), and 29.4 and 25.9 months with and without adjuvant therapy (HR 0.79, 95% CI 0.61-1.02). Stage, R0 resection, re-resection for GBC and adjuvant chemotherapy remained associated with improved OS in multivariate analysis. Taken together, only 25% of patients in the more contemporary cohort of 2017-2019 had complete (R0) resection and completed adjuvant chemotherapy. Conclusions: Complete resection, including reresection for incidentally diagnosed GBCs, and adjuvant chemotherapy were associated with improved outcomes in this retrospective cohort, yet many patients were not able to complete these treatments. Neoadjuvant strategies may improve treatment delivery and ultimately, outcomes. [Table: see text]


Postprandial hyperglycemia is a potent risk factor for cardiovascular disease. Serum glycated albumin (GA) has been reported to reflect postprandial blood glucose fluctuations. In the present study, we assessed the possible correlation of GA with the presence of carotid plaque to evaluate the potential clinical usefulness of GA for predicting atherosclerotic cardiovascular complications in patients with type 2 diabetes.


Targeted at reinforcement design rarely considered the effect of intermediate principal stress,the true triaxial test is taken to study the effect of intermediate principal stress on the strength of reinforced loess in this paper.The results show that intermediate principal stress has a significant influence on the strength of reinforced loess,and the strength of reinforced loess has a increasing trend in the whole with the increase of coefficient of intermediate principal stress.For a given ratio of the intermediate principal stress,as the value of b is small,the strength of reinforced loess tends to increase as the reinforced layers increase,but as the value of b becomes bigger,it shows a contrary tendency,and analyzes the influence of intermediate principal stress on the strength index.Intermediate principal stress has a great influence on the strength of reinforced loess especially when taking the transversal reinforcement,so the effect of intermediate principal stress can not be disregarded during the reinforcement design.


Finned tube heat exchangers are used in many technological applications in both civil and industrial sectors. Their large-scale use requires a design aimed at reaching high thermal efficiency as well as avoiding unnecessary waste of resources in terms of time and costs. Therefore, in the last decades, research in this area has developed considerably and numerous studies have been conducted on modeling in order to predict heat exchangers (HXs) performance and to optimize design parameters. In this paper, the main studies carried out on plate-finned tube HXs have been collected, analyzed, and summarized, classifying existing models by their scale approach (small, large, or multi-scale). In addition, the main methods of design optimization with a focus on circuitry configurations have been illustrated. Finally, future developments and research areas that need more in-depth analysis have been identified and discussed.


A grazing system simulation model was developed that treated pasture as a series of
horizontal layers with a depth of an animal bite, but varying bulk density and leaf content. It is
assumed that the surface is exploited randomly in feeding stations of area determined by the animal
reach. At each feeding station encounter one layer is removed during grazing so the sward surface in
time becomes a mosaic of varying composition. Animals exploit or reject a feeding station on the
basis of comparison with the immediately preceding encounter. Model parameters were taken from
published accounts of sward properties and animal grazing behaviour, and were tested using data
from field trials. Introduction of a higher yielding dairy cow to Irish grazing could change the balance
between feed demand and available grass. The model was used to show that maximum mean daily
intake in mid-lactation from Perennial Ryegrass may be limited to 16 kg day-1which is adequate for
the current system but significantly less than the demand of high yielding dairy cows (>6000 l per
year). In mid-lactation the high feed demand of highly bred cows may over-ride selectivity. When not
selective the mean daily intake is increased to 20 kg, which approaches the demand but has
implications for sward management.


Purpose: To reduce gastrointestinal (GI) and genitourinary (GU) side effects in patients receiving Cesium‐131 prostate brachytherapy by modifying the treatment planning technique. Methods and Materials: 15 patients were pre‐planned with Cs‐131 according to the modified peripheral loading technique. For the next 15 patients, the planning technique was modified to increase seed placement around the periphery of the gland, reduce the prostate V150, and decrease dose to the rectum. All implants were conducted with pre‐loaded needles and stranded seeds. Dose volume statistics were analyzed according to a 2‐sided T‐test with 95% confidence interval. The follow‐up range was 6 to 19 months. Maximum GI and GU toxicity scored according to the Common Terminology Criteria for Adverse Events (NCI, version 3.0) were reported for all patients. Minimum PSA value in the 6–11 month follow‐up period was reported. Results: The number of seeds and total activity implanted decreased 22.0%(p<0.0001) and 14.9%(p<0.005), respectively. The prostate V150 decreased 19.2%(p<0.02), the rectum D10 and V100 decreased 24.8%(p<0.0002) and 73.3%(p<0.04), respectively. The prostate V100, V90, D90 and urethra UV150 were unchanged. Before the planning change, 40% (6 out of 15) of patients reported higher grade (Levels 2 and 3) GI toxicity and 53.3% (8 out of 15) of patients reported higher grade GU toxicity. After the planning change, these values reduced to 13% (2 out of 15) GI and 40% GU (6 out of 15). 4 patients in the first group and 1 in the second group experienced urinary retention. The mean PSA follow‐up was 8.93 and 8.5 months for the first and second groups, respectively. The minimum PSA reported was unchanged (1.00 in the first group, 0.98 in the second group,p=0.95). Conclusion: Implementing these treatment planning changes reduced the severity of GI and GU side effects without compromising dosimetric coverage of the prostate or initial PSA response.


The learning curve of endoscopic ultrasound (EUS) and EUS‐fine‐needle aspiration (EUS‐FNA) is long with existing data suggesting that > 150 supervised cased are required! To shorten the learning period of EUS, a few learning tools have been developed. The learning tools especially designed for EUS and EUS‐FNA (live animal model, computer simulator, simple phantom, EUS RK model) were reviewed. There is a need to develop learning tools for EUS that require no maintenance, are inexpensive, readily available, and proven to shorten the learning curve. Few centers have the faculty expertise and adequate caseload (to sufficiently train fellows in EUS).


Using peseudostatic test method, the experimental research on two dog-bone style rigid connection specimens and one normal bolt-welded joint specimen was carried out. Through imposing low period repeating horizontal load on these specimens, their destroying behavior and working behavior have been analyzed. The conclusion indicated that the dog-bone style rigid connection has bigger connection rigid and better behavior of absorbing earthquake energy. The welding seem stress of beam-flange is the major factor which decides the behavior of dog-bone style rigid joint and only the better welding can exert the function of the dog-bone.


The article deals with the search for rational and balanced solutions to ensure maximum safety of rolling stock movement, taking into account the minimization of costs and technical measures. The paper presents a mathematical model for calculating the effect of rheological characteristics of lubricants on the service life of heavy-loaded friction units of rolling stock. The scheme of interaction of a wheel with a rail at a single-point contact is presented in the form of contacts of two cylinders of infinite length. The results of numerical analysis of the found analytical dependences of the influence of the plasticity parameter on the coefficient of friction, the influence of the plasticity parameter on the supporting force created by the lubricant layer during the movement of surfaces are presented. The influence of the coefficient of friction on the safety of rolling stock movement in the curved sections of the track is established.


This dissertation examines the developmental controls of Swedish children; primarily of four-year-olds. The aim is to show how these controls have constituted children as normal or deviant, and on ...


Impatiens glandulifera (Balsaminaceae) is one of the most widely distributed invasive alien plants in Europe. In the Czech Republic, it first colonized open riverbank habitats and more recently less humid and more shaded habitats where it comes in contact with two congeners, the native I. noli-tangere and earlier invader I. parviflora; both these species are likely to be affected by competition with I. glandulifera. A reciprocal sowing experiment was established to explore the performance and possible microsite differentiation of the three Impatiens species in the field. Three triads of plots, each dominated by one Impatiens species, were established in surroundings of a river with a fine-grained mosaic of woody and meadow vegetation in southern Bohemia, Czech Republic. The plots were protected from the natural input of seed by cutting the vegetation 20 cm above the soil surface and covering the surface with a cloth during the period of seed release. Each plot consisted of a subplot sown with a mixture of seed of all three species collected at the same locality and a control subplot with no seed added. Sites dominated by I. noli-tangere and I. parviflora were suitable for germination of all Impatiens species; the I. parviflora sites were more suitable for the establishment and further development of Impatiens plants. This indicates that I. noli-tangere was outcompeted from sites currently dominated by I. parviflora and further spread of I. glandulifera into sites occupied by the other Impatiens species is likely. Experimental plots in sites dominated by I. glandulifera were unsuitable for growth of all species, including its own seedlings.


In this paper we proposed a system which can monitor Fish Tank continuously. It is actually a wireless sensor network which is having one base station and several nodes. Salinity of the water is very important parameter which is responsible for the difference in environment from marine conditions. Salt is an important ingredient for influences the environment where fishes live. Fishes life is best between the pH range 7.0 to 8.0. If the pH changes by a small value then it is stressful for fishes. Temperature is also another parameter which affect pH and in turn affect fishes life. The developed system monitors these three parameters affecting the fresh water fishes. This system is based on the microcontroller. KeywordsFish tank, Salinity, pH, Temperature. I.INTRODUCTION Freshwater fishes are the fishes which spend their lives in freshwater such as rivers and lakes with a salinity of less than 0.05% [1]. These environments differ from marine conditions in many ways and the most common being salinity. In order to survive in fresh water, the fish needs a range of physiological adaption's in order to keep the ion concentrations of their bodies balanced. Salt is natural ingredient for purifying water and for energizing stressed and wounded fishes [1]. However, salt is effective only in small quantities and excessive use can be harmful. Tap water usually has very low salt content and the addition of salt make the fishes feel home and defeat toxic chemical and avoiding fish poisoning. Also, the salts help fishes in gaining energy due to illness and stress thereby increasing the oxygen intake and flow of blood. The pH is equally a key parameter which influences the environment where fishes live. Usually fishes can live in pH ranges from 6.0 to 8.0, but their quality of life is best between pH 7.0 to 8.0[2]. The change in the value of pH even by small amount will be more stressful for fish. Freshwater has a natural pH in the range 6.0 to 8.0. As the pH value drops below 6.0, the non-desirable species may begin to invade fish population and aluminium ions from nearby soil may be released into the water which can kill the fishes. The most chronic effect of increased acidity may disturb the reproduction cycle making fishes sterile. The increase in the value of pH above 8.0 can kill the adult fishes, harm the juvenile fishes and increase the toxicity of other substances like ammonia. Temperature is other key parameter which influences the value of pH. Many substances exhibits increased toxicity levels at elevated temperatures which affect the fishes. The temperatures also contribute to the growth and reproduction of the fish. One approach to solve this problem would be to employ a Sensor Network that would enable users to monitor the required factors such as pH, temperature and level of salinity. Sensor Networks offer many attractive low cost solutions to monitor these conditions [3]. Few applications of Sensor Networks are volcano monitoring, machine monitoring, animal tracking, vehicle tracking monitoring etc. II.PROPOSED SYSTEM Transmitting NodeFig.1 shows the transmitting node of the proposed system. In this system we have used a Microcontroller PIC 18F4520. It has 10 bit inbuilt ADC. For pH measurement, pH electrode is used. This pH electrode is actually a combination electrode. The modern electrode is a combination electrode composed of two main parts: a glass electrode and a reference electrode. pH is determined essentially by measuring the International Journal of Engineering Trends and Technology (IJETT) – Volume 10 Number 8 Apr 2014 ISSN: 2231-5381 http://www.ijettjournal.org Page 409 voltage difference between these two voltages. The next is Temperature sensor which is LM 35. This is very familiar sensor for us. Salinity of the water can be measured by measuring the conductivity of the water. So conductivity sensor is used here, conductivity measured in Siemens per meter. Zigbee is used for wireless transmission of data. Receiving NodeFigure.2 Receiving Node At the Receiving Base station data has been received and stored for the monitoring purpose. For which I have used a Personal computer to store the data. III. HARDWARE DESCRIPTION MicrocontrollerPIC18F4520 microcontroller is used.It has high computational performance at an economical price.High-endurance, Enhanced Flash program memory.PIC18F2420/2520/4420/4520 family introduces design enhancements that make these microcontrollers a logical choice for many highperformance, power sensitive applications.


Christine Tasson introduced an algebraic notion of totality for a denotational model of linear logic in the category of vector spaces. The notion of total boolean function is, in a way, quite intuitive. This note provides a positive answer to the question of completeness of the "boolean centroidal calculus" w.r.t. total boolean functions.


ABSTRACT As global neoliberalism continues to take root, States aim to produce linguistically-skilled human capital to gain an advantage within highly-competitive market conditions. With this relationship in view, English language proficiency constitutes a 'rational' educational pathway for national and personal-level success within an outwardly meritocratic knowledge economy. Yet, in Japan, as in many other locales, English has been accused of strengthening pre-existing power relations. Accordingly, this inquiry draws on Bernstein's pedagogic device, to address the nested fields of production, recontextualisation, and reproduction shaping educational practice. Regarding production, normative OECD discourses framing essential key competencies favour an epistemic hierarchy privileging the orthodoxy of free-market capitalism. Through unequal pedagogic reform, meanwhile, the recontextualisation of regulatory discourse limits valued forms of knowledge to learners attending prestigious mass-market institutions. This, in turn, holds implications for reproduction. Through recognition and realisation, the classification and framing of English as a 'valid' knowledge privilege students from middle-class households. The appropriation of English as a 'rational' contact point for global communication, business, and finance thereby risks obfuscating the socio-economic order determining its practice.


In this study, white organic EL devices with microcavity structures were developed. A flexible high-resolution AMOLED display with low power consumption using RGBW sub-pixels formed by a color filter method was fabricated. In addition, side-roll and top-roll panels with bezels that are not viewable from the front were also developed using the flexible AMOLED display.


This study was designed to investigate the ameliorative effect of Quercetin on Fenvalerateinduced biochemical alterations in human erythrocytes invitro. Erythrocytes are useful model to study the interaction of pesticides with biological membranes. Pesticides are thought to exert damaging effect on biomembranes through free radical generation; therefore antioxidants can play a crucial role in offering protection against pesticide induced oxidative damage. Quercetin is a potential antioxidant, known to be able to protect cells against oxidative damage. The biochemical parameters chosen to evaluate the effect of Quercetin were lipid peroxidation (LPO), selected antioxidant and membrane bound enzymes in erythrocytes. No statistical differences were found in the Quercetin treated groups compared with the control group. Following in vitro exposure, Fenvalerate caused a significant induction of oxidative damage in erythrocytes as evidenced by increased levels of thiobarbituric acid reactive substances (TBARS), and decreased levels of GSH. The activities of superoxide dismutase (SOD), catalase (CAT), Glutathione peroxidase (GPx) were found to be significantly reduced in Fenvalerate treated erythrocytes compared with the control erythrocytes. However, Quercetin pretreatment significantly prevented the decrease in the activities of antioxidant enzymes and membrane bound ATPases. The beneficial effects of Quercetin observed here presumably reflect the ability of this flavonoid to protect cells from the toxic effects of Fenvalerate.


Through this scientific research report "MANAGEMENT ASPECTS IN THE PERSONNEL REMUNERATION AND STIMULATION ACTIVITIES AT S.C. TASMANIA S.R.L." we plan to investigate the remuneration and stimulation method from the human resources department within S.C. Tasmania. Studying in detail the personnel's remuneration and stimulation we have tried to present the main policy aspects at S.C. Tasmania in human resources domain: Integration of the human resource management in the overall management of the company;Creating a favorable climate for conducting the activities;Professional development;Evaluation and motivation;Employee involvement in the decision making process. We conclude that the development of management theory and practice in personnel remuneration and stimulation in an open field for performance and professionalism of the managerial team of Tasmania S.R.L.


Abstract. New particle formation (NPF) events are defined as a
sudden burst of aerosols followed by growth and can impact climate by
growing to larger sizes and under proper conditions, potentially forming
cloud condensation nuclei (CCN). Field measurements relating NPF and CCN are
crucial in expanding regional understanding of how aerosols impact
climate. To quantify the possible impact of NPF on CCN formation, it is
important to not only maintain consistency when classifying NPF events but
also consider the proper timeframe for particle growth to CCN-relevant
sizes. Here, we analyze 15 years of direct measurements of both aerosol size
distributions and CCN concentrations and combine them with novel methods to
quantify the impact of NPF on CCN formation at Storm Peak Laboratory (SPL),
a remote, mountaintop observatory in Colorado. Using the new automatic
method to classify NPF, we find that NPF occurs on 50 % of all days
considered in the study from 2006 to 2021, demonstrating consistency with
previous work at SPL. NPF significantly enhances CCN during the winter by a
factor of 1.36 and during the spring by a factor of 1.54, which, when combined with
previous work at SPL, suggests the enhancement of CCN by NPF occurs on a
regional scale. We confirm that events with persistent growth are common in
the spring and winter, while burst events are more common in the summer and
fall. A visual validation of the automatic method was performed in the
study. For the first time, results clearly demonstrate the significant
impact of NPF on CCN in montane North American regions and the potential for
widespread impact of NPF on CCN.


This article suggests to consider uvenal journalism from the point of view of standard approaches and naive presentations of publishers about the product of journalistic activity, to distinguish the bias errors of publishers, understand their primary reasons. An author presents experience of Tomsk amateur editions managing to overcome standard presentations, and also offers certain methods, allowing to realize, transform and perfect existent standard, naive presentation about journalism and to show out child's mediaproduct on a professional level.


The dynamics of a particle in an expanding cavity is investigated in the Klein-Gordon framework in a regime in which the single-particle picture remains valid. The cavity expansion represents a time-dependent boundary condition for the relativistic wave function. We show that this expansion induces a non-local effect on the current density throughout the cavity. Our results indicate that a relativistic treatment still contains apparently spurious effects traditionally associated with the unbounded velocities inherent in non-relativistic solutions obtained from the Schrödinger equation. Possible reasons for this behaviour are discussed.


The challenge for the global community is to find ways to deliver to developing countries the electricity services associated with economic and social development without environmental damage and to do so in ways that strengthen the social fabric of North-South relationships rather than weaken it. At a time when demands for electricity services are rising rapidly in developing countries and the global environment is already under stress, the use of energy from petroleum and natural gas for electricity generation is becoming increasingly expensive while coal, a major cause of environmental concern, remains abundant. This suggests one of the great scientific and policy predicaments of our time. This paper reviews the issues and options that are central to the implementation of environmentally responsible strategies for electric power system development.


Facebook is the largest social media in the world. All social media applications made by Facebook cannot be accessed simultaneously in approximately 6 hours. This happens not only in Indonesia, but in all countries in the world, on October 5-6, Indonesian time. With this case, various comments and opinios from people on Twitter related to the Facebook case were down. Positive or negative comments popping up on twitter. Sentiment analysis is used to identify positive and negative comments. In this study, positive and negative comments will be classified using Vader and nave Bayes classification. The data collected was 500 data from twitter related to the Facebook down case. From the calculation results, positive sentiment was obtained as much as 33.92% and negative sentiment with 66.08% results. Based on the results of the visualization with wordcloud, the words that appear the most are the word facebook down for positive and negative sentiments. The results obtained from the confusion matrix table from the classification model using data sharing, 80% training data and 20% testing data, with the classification method using Naive Bayes with TF-IDF word weighting, the accuracy value is 73.69% and for the Count Vectorizer is 70.18%.


The objective of this work is to offer ways to favor the didactic orientation of tutors in order to promote the communicative competence in 10th grade students. To accomplish such objective, it is important to make an appropriate selection of the content in the syllabus of this subject. This content should be motivating for the students that are going to receive this subject, for example the asking of questions about nowadays communicative situations in order to promote a conversation or a dialogue, the exchange of information and the participation of the students in independent works in order to enable them to construct their own written texts making use of the correct linguistic means that the Spanish language offers. It was used the method productive independent work and procedures such: reading, analysis, synthesis, examplification and explication.


INTRODUCTION:Endometriosis-associated symptoms like menstrual and non-menstrual pelvic pain can be associated with fatigue. This study evaluated the impact of elagolix, an oral gonadotrophin-releasing hormone antagonist, on fatigue among endometriosis patients.METHODS:We conducted a phase III double


The demand of electricity is increasing day by day. For economic emancipation and in order to meet the Millennium Development Goals, the electricity growth that is generating more electricity, building more transmission/ distribution capacity, bringing more area/ population under electricity coverage and ensuring more efficient management of these are the essential issues. According to the power sector growth in the country, the country needs new 400 MW power each year to meet the growing demands. Building of this particular infrastructure require large amount of capital and is encountering increasing difficulties to finance the required capacity either through the government budget or even by the international development agencies and financing organizations. But the government of Bangladesh is unable to provide the finance to set up new power plants according to the growing demand. That is why in 1996 the Government of Bangladesh (GOB) has decided to build power plants in private sectors and Independent Power Producers (IPPs) launched their business in Bangladesh. In this paper the brief history of the private sector power plants in Bangladesh, their problems and prospects are discussed.


AIM
Hemochromatosis (HH) was a common inherited disease characterized by iron overload. This disease is usually the result of mutations in the HLA-linked hemochromatosis gene (HFE). The aim of this study was to evaluate the frequency of HFE mutations in a group of Venetian hemodialysis patients.

METHODS
Sixty-one hemodialysis patients, 62 patients with laboratory findings suggestive for iron overload, 57 repeat blood donors were enrolled in the study. HFE mutations were detected by using a commercial strip assay.

RESULTS
In this study only H63D and C282Y mutations were observed. The overall prevalence of HFE mutations was 40.9% among hemodialysis patients, 30.6% among patients with laboratory findings of iron overload and 15.8% among blood donors.

CONCLUSION
A high prevalence of HFE mutation among hemodialysis patients was observed. Prevalence of HFE mutation in this group was 40.9%, significantly higher than results observed among blood donors (15.8%, P<0.005) or among patients with laboratory signs of iron overload (30.6%, P<0.01). These data are, at present inexplicable, and this results need further confirmation.


Epigenetic factors recruit gene expression machinery toward organogenesis development during the differentiation process. Epigenetic factors' interaction relationships with Plant growth regulators (PGRs) signaling are focused in this study. Expression profiles of some dedifferentiation and differentiation-distinctive genes were quantified throughout the regeneration process of Prunus persica from cotyledons explant. Auxin; indole-butyric acid (IBA) and indole-acetic acid (IAA), and Cytokinin; thidiazuron (TDZ) and 6-benzyladenine (BA) with different combinations were used to test their ability to induce callogenesis and shoot differentiation. TDZ in combination with IAA revealed highest shoot regeneration percentage (70%) followed by combination of BA with IAA and scoring 66%. Our findings demonstrated that methyltransferases-responsive genes are accumulating at extremely low levels during callus formation while they show highest level of expression during shoot formation on both TDZ and IAA, and BA and IAA combinations, and very low expression level on TDZ and IBA (differentiation failure medium). In a similar manner, DICER-LIKE1 (DCL1) displayed high expression levels during the differentiation process on TDZ and IAA and BA and IAA and Extremely Low expression levels during callus formation on all PGRs combinations as well as cotyledons explant. It was observed that the balance between the functions of the two protein groups Polycomb group (PcG), and its counteracting Trithorax group (TrxG) is manipulating plant development process. SHOOT MERISTEMLESS (STM), a member of Class 1KNOX gene family, revealed significant high expression in both dedifferentiated and differentiated calli.


The removal efficiency of copper ions in aqueous solutions was investigated by adsorption process on pure and modified geopolymer, synthesized from fly ash. A type F (as defined in ASTM C618) fly ash from the Croatian power plant Plomin 2 (Plomin) was used in the present study. The batch experiments were carried out as a function of solute concentration at constant temperature (296 K) and particle size (90-500 μm). The sorption capacity of copper ions increases with the initial concentrations of solute and for the modified geopolymer it reaches its maximum value at qe = 0.712 mmol/g and for the pure geopolymer it reaches its maximum value at qe = 0.814 mmol/g. Kinetic studies based on Lagergren pseudo-first order, Ho pseudo-second order, Ritchie second-order and Elovich rate equations were used to test experimental rate data. All the models were analyzed using nonlinear regression technique. The results obtained indicate that, both, pure geopolymer and modified geopolymer could be used as alternative materials for the wastewater treatment. Nevertheless, pure geopolymer shows slightly better efficiency. Kinetic study has shown that the best fit is achieved when the Elovich model was applied.


The present invention relates to a detector arrangement in the instrument for analyzing individual liquid sample volume microliters housed in microchannel structures present on the disk-shaped microfluidic device and / or nanoliter range. The proposed detector arrangement comprises a detector head which is supported so as to be linearly displaced, a positioning drive and control in a first radial plane transverse to the central axis of the rotary drive cooperating. Rotating member, in the second radial plane which is in parallel relationship with said first radial plane, is rotatably supported about the central axis. The vacuum source is connected to the rotating member, through flat upper surface and air flow communication with the rotary member, thereby distributing widely negative pressure over the upper surface. Rotating member, carries a disc-shaped substrate in a state adhering contact with the upper surface, thereby spinning the substrate at equidistant-like angle to the detector head.


ABSTRACT: The construction of embankments on soft saturated soils can be a challenge due to the low shear strength and high compressibility of these soils. The same may be true for constructions on porous collapsible soils, because the collapse of the soil structure can lead to large foundation soil deformations leading to damage to the embankment, particularly in the case of bridge abutments. Conventional piles and granular columns have been used to stabilize such embankments when there are limits for embankment settlements. More recently, geosynthetic-encased granular columns have been increasingly used as an alternative solution. This study examined the performance of geosynthetic-encased columns for the stabilization of embankments on porous collapsible structured unsaturated soil. Field load tests were performed on conventional sand and gravel columns and on geotextile-encased sand columns and on geogrid-encased gravel columns. During testing, the collapse of the surrounding soil was induced by water...


This paper is the development of a new method of obtaining water based on dehumidification method.Water privation affects more than 884 million people in over 43 countries. According to the WHO, th ...


A computer program for recognizing and counting the track of ions that are detected with polycarbonate detector has been written using MATLAB software. There are different programs for counting the track of ions in different detectors. Algorithm of this program specially has been written for polycarbonate detector and also for low magnification of optical microscope. Thus, with this method as per image of optical microscope, greater numbers of ions are visible and general distribution of ions can be better known. However, the accuracy of counting program is very high.


In situ calibration of a rainfall impact disdrometer using a collocated tipping bucket rain gauge has been previously reported. Several factors affect the accuracy of this technique. These include the specific mathematical model of the transducer, tipping bucket errors, clock/time accuracy, switch delay time and calibration reference window used to update the transducer model coefficients. In this work, two general forms of an empirical transducer model have been investigated: a simple two-coefficient power-law and an Nth order polynomial, where the input is a specific measure of the electrical signal from the transducer and the output is the hydrometeor diameter. Even though previous work allowed for a more general non-linear transducer model description, the subsequent implementation of an adaptive calibration algorithm required use of a steepest descent recursive gradient search algorithm, which can be difficult to implement in a real-time system. Linear transducer models allow an implementation suitable in a real-time signal processing system.


Powdery mildew is the most common disease of barley in the Czech Republic and winter barley plays a crucial role in the winter survival and reproduction of the pathogen. This study was aimed at identifying resistance genes in winter barley cultivars grown in the Czech Republic from 1971 to 2005 by using the method of postulation. Forty-one cultivars and a parental line were tested at the seedling stage for their reaction to 32 selected isolates of Blumeria graminis f. sp. hordei. In total, 26 resistance spectra were detected and the following 18 resistance genes were found: Mla6, Mla7, Mla8, Mlal3, Mlal4, MlaMu2, MlaNo3, MlaRu4, Mig, Mlh, MILa, Mlra, Ml(Bw), Ml(Ch), Ml(Dr2), Ml(Dt5), Ml(IM9) and Ml(St). Two cultivars ('Kiruna' and 'Sorna') exhibited heterogeneity for mildew resistance. Another source of Mlal3 and a possible centre of origin of Ml(Bw) are discussed.


This article describes the flora of Boburnoma and their peculiarities in the English translation. By getting acquainted with the scientific worldview of ecology mentioned in the "Boburnoma", each reader will have a conscious understanding of the wonders of nature, flora and fauna, natural resources, respect for fresh air, protection and transmission to future generations Our country is one of the oldest centers of civilization in the world. Scientists living and working in the land of ancient Turan have made a great contribution to the development of world history, science and culture. These works are especially revered as immortal monuments of world civilization. One of such monuments known and famous all over the world is Zahiriddin Muhammad Babur's "Boburnoma".


The key in socialist theoretical construction lies in the adherence to the socialist tenet.Under such a precondition,we can have a correct understanding to the various relations in socialist construction,guide effectively the socialist practice,regulate relations of various sorts,construct a harmonious society and constantly promote the progression of the socialist cause with Chinese characteristics.


Introduction: Rapid Biophysical profile is quicker and easier to do than a full biophysical profile or a contraction stress test. Furthermore, the rBPP is regarded to be just as useful as a complete biophysical profile. Although the link between rBPP and BPP has been widely used, research is scarce. As a result, the current study looked into the relationship between the two tests, as well as their predictive ability in high-risk pregnancies. Material and Methods: 60 pregnant women with ≥ 32 weeks of singleton gestation, were randomly selected during their hospital visit. They were subjected to USG scan. NST AFI, fetal breathing, fetal tone, and fetal movement will be examined to complete the BPP test. After a 10-minute break, SPFM will be carried out by the same examiner to finish rBPP test. These results were compared with the perinatal outcome. Results: The present study showed that scores of rapid Biophysical Profile have strong positive correlation with scores of biophysical profile (r 2 = 0.531, P = <0.001) and it was statistically significant. The rapid/ modified biophysical profile test is 78% sensitive to Biophysical profile test, which means 78% times the function can identify the cases and classify correctly, as diseased cases with PPV of 61%. Conclusion: The statistically significant positive correlation between rBPP and BPP has been revealed. Due to its simplicity, rapidity, less expensive and no need for experience interpreter, the rBPP can be used as a primary screening antepartum fetal surveillance in the overcrowded obstetric center.


TO THE EDITOR:

We read with great interest the article by Matthay et al. ([1][1]). We would like to comment on the total-body and red marrow dose estimates presented in this publication and discuss possible alternative methods of dosimetry analysis. These points highlight the need for the


The purpose of this study is to test the persuasive effects of visual metaphors in advertising. Advertisements containing visual metaphors deliver persuasive arguments in visual modality and metaphorical style of rhetoric, both of which may increase the persuasiveness of messages. The study has three message conditions that are advertisements containing (a) non‐metaphorical (literal) visual image with verbal argument; (b) metaphorical visual image with verbal argument; and (c) metaphorical image without accompanying verbal argument. Cognitive elaboration, source credibility, ad attitude, brand attitude, product belief, and purchase intention are considered as outcomes. The study results suggest that visual metaphors may be more persuasive due to both visual argumentation and metaphorical rhetoric. The theoretical explanations and managerial implications of the findings of this study are further discussed.


To measure the progress of diapause termination in December and March and the difference in diapause intensity between populations from two altitudes, Coccinella septempunctata adults were exposed to 25° and to photoperiods 18L:6D or 12L:12D and the oviposition was recorded.


This paper proposes a novel quadruple-mode cavity resonator and filters. The cavity resonator Involves four modes which are similar in frequency and can be easily controlled. Meanwhile 20% volume saving can be achieved while maintaining the similar unloaded Q-factor value of the conventional designs. Moreover, as the electric field of proposed modes only exist horizontal component, the four modes can be simulated by using a pair of mental probes without any other intra-cavity coupling structure. To demonstrate the new resonator technology, a four-pole filter with 40 MHz wide filter at 2.6GMHz is designed and simulated.


In the design of high-speed permanent magnet machines (HSPMMs), comprehensive effects of design parameters on the various properties of electromagnetic loss, rotor stress, rotor critical speed, and temperature distribution must be analyzed to obtain the optimal design. The aim of this paper is to examine the effects of design parameters, such as the pole number, stator slots number, number of conductors per slot, permanent magnet (PM) thickness, PM pole arc coefficient, air gap length, rotor diameter, core length, and sleeve thickness, on multiphysics performance based on a high-power HSPMM. A reasonable design is determined according to the abovementioned analysis that satisfies all specified multiphysics constraints. The theoretical results are confirmed by the experimental results on a prototype in terms of electromagnetic, mechanical, and thermal characteristics such as back electromotive force, no-load loss, full-load current, overspeed experiment, and temperature distribution.


Foundation: sleep is recognized as an indicator of quality of life and, in a student´s daily life, it acquires great importance for its relationship with cognitive functioning and academic activities. Objective: to identify and evaluate factors associated with quality of sleep presented by the Chilean students of the Obstetric training program, according to years studied. Methods: cross-sectional and analytical study conducted in the 2018 school year in a Chilean university, which included all the students of Obstetrics, who answered a questionnaire that evaluated sociodemographic background, academic profile, previous sleep habits and sleep quality, assessed by the Pittsburgh Sleep Quality Index (PSQI) survey. Results: the behavior around the sleep habits differs significantly among courses, in the 1st and 4th year there are those who sleep less and the students of this last course are classified as the worst sleepers. The average of the PSQI components varies between 6, 6 (5th year) and 9.2 (4th year); daytime dysfunction component showed the most extreme values. Conclusions: there is a weak association between sleeping quality and sociodemographic variables, academic profile and previous sleep habits. It is only strongly associated with some components of the sleep quality survey, such as bedtime and student sleeping hours. The training program progression does not mean an increase or decrease in bad or good sleepers.


One of the major applications of statistics is the validation and comparing probabilistic models given the data. This branch statistics has been developed since the formalization of the late 19th century by pioneers like Gosset, Pearson and Fisher. In the special case of the Bayesian approach, the comparison solution of models is the Bayes factor, ratio of marginal likelihoods, whatever the estimated model. This solution is obtained by a mathematical reasoning based on a loss function. Despite a frequent use of Bayes factor and its equivalent, the posterior probability of models, by the Bayesian community, it is however problematic in some cases. First, this rule is highly dependent on the prior modeling even with large datasets and as the selection of a prior density has a vital role in Bayesian statistics, one of difficulties with the traditional handling of Bayesian tests is a discontinuity in the use of improper priors since they are not justified in most testing situations. The first part of this thesis deals with a general review on non-informative priors, their features and demonstrating the overall stability of posterior distributions by reassessing examples of [Seaman III 2012].Beside that, Bayes factors are difficult to calculate except in the simplest cases (conjugate distributions). A branch of computational statistics has therefore emerged to resolve this problem with solutions borrowing from statistical physics as the path sampling method of [Gelman 1998] and from signal processing. The existing solutions are not, however, universal and a reassessment of the methods followed by alternative methods is a part of the thesis. We therefore consider a novel paradigm for Bayesian testing of hypotheses and Bayesian model comparison. The idea is to define an alternative to the traditional construction of posterior probabilities that a given hypothesis is true or that the data originates from a specific model which is based on considering the models under comparison as components of a mixture model. By replacing the original testing problem with an estimation version that focus on the probability weight of a given model within a mixture model, we analyze the sensitivity on the resulting posterior distribution of the weights for various prior modelings on the weights and stress that a major appeal in using this novel perspective is that generic improper priors are acceptable, while not putting convergence in jeopardy. MCMC methods like Metropolis-Hastings algorithm and the Gibbs sampler are used. From a computational viewpoint, another feature of this easily implemented alternative to the classical Bayesian solution is that the speeds of convergence of the posterior mean of the weight and of the corresponding posterior probability are quite similar.In the last part of the thesis we construct a reference Bayesian analysis of mixtures of Gaussian distributions by creating a new parameterization centered on the mean and variance of those models itself. This enables us to develop a genuine non-informative prior for Gaussian mixtures with an arbitrary number of components. We demonstrate that the posterior distribution associated with this prior is almost surely proper and provide MCMC implementations that exhibit the expected component exchangeability. The analyses are based on MCMC methods as the Metropolis-within-Gibbs algorithm, adaptive MCMC and the Parallel tempering algorithm. This part of the thesis is followed by the description of R package named Ultimixt which implements a generic reference Bayesian analysis of unidimensional mixtures of Gaussian distributions obtained by a location-scale parameterization of the model. This package can be applied to produce a Bayesian analysis of Gaussian mixtures with an arbitrary number of components, with no need to specify the prior distribution.


This article traces the steps in the development of a plan, deals with planning progress in Australia, and in conclusion remarks pointedly that "A planning scheme merely tries to ensure that we spend money to the best possible advantage."


In wireless sensor networks, the importance of transporting data correctly with reliability is increasing gradually along with the need to support communications between the nodes and sink. Data flow from the sink to the nodes requires reliability for control or management that is very sensitive and intolerant of error; however, data flow from the nodes to the sink is relatively tolerant. In this paper, with emphasis on the data flow from the sink to the nodes, we propose a mechanism that considers accurate transport with reliability hop-by-hop. During the process of sending the data, if errors occur or data is missing, the proposed mechanism supports error recovery using a fixed window with selective acknowledgment. In addition, this mechanism supports congestion control depending on the buffer condition. Through the simulation, we show that this mechanism is accurate, reliable, and proper for transport in wireless sensor networks.


Based on the similarity between the orientation of the fiber in the stitched laminates and the stream in the flow around a cylinder,a flow field model is built for the elastic constants of the stitched laminar,which is a steady 2D non-compressible non-viscous ideal flow without swirl in a finite space.The boundaries of the flow field and the unit cell of the stitched laminates are identical,and the surface of the body in the flow field is the same as the section shape of the stitch thread.The velocity variation in the flow field describes the fiber volume fraction variation in the unit cell of the stitched laminar, and the streamline shape describes the fiber orientation.Using the flow field model,the elastic properties of the stitched laminar are calculated by the micromechanics and the homogenization method,and the results are in good agreement with those of the test.Finally,the effects of the stitch parameters on the laminar elastic constants are discussed.


AUTHOR Jaranson, James M.; Bamford, Pauline TITLE Program Models for Mental Health Treatment of Refugees. INSTITUTION : nnesota Univ., Minneapolis. Refugees Assistance Program Mental Health Technical Assistance Center. SPONS AGENCY National Inst. of Mental Health (DHHS), Rockville, MD. PUB DATE 15 Jul 87 CONTRACT NIMH-278-85-0024-CH NOTE 51p. AVAILABLE FROM Refugee Assistance Program--Mental Health Technical Assistance Center, University of Minnesota, Box 85, Mayo, Minneapolis, MN 55455. PUB TYPE Reports Descriptive (141)


Over its lifetime, a Web service is likely to be reused across
several development projects, such that in each of them different interfaces
are required from it. Implementing, testing, deploying, and maintaining
adapters to deal with this multiplicity of interfaces can be costly
and error-prone. The problem is compounded in the case of services that
do not follow simple request-response interactions, but instead engage
in conversations comprising arbitrary patterns of message exchanges.
This paper proposes a language for specifying adapters for conversational
services. The language is based on six composable operators that
are endowed with a formal semantics defined in terms of Petri nets. The
formal semantics is used as a basis to statically check the correctness of
the specified adapters. The proposal has been validated through a prototype
implementation of an execution engine and a tool that converts
adapter specifications into Petri nets.


The role of rural migrant workers in the dissemination of urban and rural culture was studied.The results showed that migrant workers influence traditional restrained rural society to a certain extent through dissemination,while the dissemination and reception have the performance of low-level,imbalance and hybrid for migrant workers' limitation and mass media' s restraint.On the basis of this,several countermeasures were put forward,such as fully display government's coordinating role and mass media's guiding function,promoting migrant workers' quality.


Thank you very much for downloading jacobean and caroline tragedies. As you may know, people have look hundreds times for their chosen novels like this jacobean and caroline tragedies, but end up in malicious downloads. Rather than enjoying a good book with a cup of coffee in the afternoon, instead they are facing with some harmful virus inside their desktop computer. jacobean and caroline tragedies is available in our book collection an online access to it is set as public so you can download it instantly. Our digital library saves in multiple locations, allowing you to get the most less latency time to download any of our books like this one. Merely said, the jacobean and caroline tragedies is universally compatible with any devices to read.


We construct a holographic model for dark energy in the Brans-Dicke cosmology by using the holographic principle considering the Barrow entropy instead of the standard Bekenstein-Hawking one. The former arises from the effort to account for quantum-gravitational effects in black-hole physics and, according to the gravity-thermodynamic conjecture, in the cosmological framework. In order to explore the cosmological consequences of our model, we consider the Hubble horizon as the IR cutoff. We investigate both the non-interacting and interacting cases with the sign-changeable and linear interactions, showing that they can explain the present accelerated phase of the Universe expansion, in contrast to the standard Holographic Dark Energy model. We then perform the stability analysis according to the squared sound speed. We find that, whilst the non-interacting model is unstable against small perturbations, the sign-changeable interacting one can be stable only for suitable values of the model parameters. On the other hand, the linear interacting model always predicts a stable Universe. The consistency of the model with respect to cosmological observations is discussed.


It is shown that nucleons in nuclei of elements are linked NOT by nuclear forces, but by the overall flow of electromagnetic energy circulating in the volume of the nucleus. This assumption allows us to explain some properties of the intranuclear interactions and some well-known observations.


The analysis of existing priorities in the development of the Arctic natural resources – hydrocarbons and marine bioresources – has been carried out. The problems and prospects of organizing logistics and transport corridors for trade by goods produced in the North and in the central regions of Russia have been considered; some issues of control over the marine area in the Arctic have been reviewed. Ключевые слова: экономика, логистика, транспортные коридоры, Арктика, углеводороды, морские биологические ресурсы, Северный морской путь, государственная программа, российские компании, регионы.


seventeenth century to aid the empire's modernization, evolved into an anachronistic and repressive instrument that interfered with Russia's further modernization in the nineteenth century. Readers may regret Raeff s comparatively brief treatment of the last half century of imperial Russia's history, but this is largely a matter of preference, focus, and interest. This is a learned and thoughtful volume, the likes of which we have far too few in this time of ever-narrowing scholarly specializations.


The ability to control magnetism in sub-picosecond timescales using laser pulses has potential applications in fast magnetic devices. It has been demonstrated that a single femto-second laser pulse can reverse the magnetization of a film within a few picoseconds [1], a phenomenon called as all-optical switching (AOS). However, this phenomenon thus far has been observed only in ferrimagnetic GdFeCo films. On the other hand, ferromagnetic films, which are of greater interest than ferrimagnets in many technological applications, need multiple laser pulses for magnetization reversal [2], making the overall effect slow and energy inefficient. Fast, singleshot switching of a ferromagnet can open up new avenues for spintronic devices that operate at unprecedented picosecond timescales, thereby making them viable non-volatile replacements for silicon based RAMs and logic devices.


This paper introduces a 5G network based on the fusion of RoF and PWoF. Wireless signal transmission and electric energy transmission are integrated through optical fiber network. The experimental simulation of the transmission capacity and efficiency of the system shows that the system can provide the power required by the remote antenna unit(RAU) and concentrate the power supply system in the central control system. This paper also builds the basic framework of the fusion system, sorts out the experimental ideas, simulates the system with software, and finally verifies the reliability of the fusion system.


It is a retrospective, comparative, observational study conducted in the Department of obstetrics and gynecology, Bombay hospital from 1 st August 2010 to 31 st July 2011, where comparison was done between 22 patients undergoing non decent vaginal hysterectomy (NDVH) and 29 patients undergoing abdominal or laparoscopic hysterectomy. Parameters analyzed were operating time, estimated blood loss, post operative pain, hospital stay, cost effectiveness and complications. Results: The demographic profile was similar for all three groups. The vaginal group included a large number of patients with high risk factors and co-morbidities. The operating time, average hospital stay, pain score, blood loss and post-operative complications were more in the abdominal and laparoscopic groups. No patient in the vaginal group required conversion to abdominal or laparoscopic hysterectomy. Conclusion: Benign uteri of upto 16 weeks sizes and fibroids upto 10.5 cm. could be removed vaginally with no increased risk of surgical or post-surgical complications.


Second harmonic generation is employed to increase LIGO's sensitivity in the shot noise dominated bandwidth (100 Hz and above) by introducing squeezed states through the dark port of the interferometer. This project characterizes and improves the second harmonic generation of periodically poled KTP in a resonant cavity locked by a PDH servo. These enhancements include custom mechanical stages to control movement of the mirrors in the horizontal direction and retain information about optimal mirror positions if the mirror mounts need to be moved. Additionally, a digital temperature controller featuring Beckhoff Ethercat terminals and TwinCat PLC software. The servo's response characteristics (set-temperature response and step function response) have been analyzed and suggest stable performance on the order of days.


Xiao′s family of Lanling was influenced by the scholarly culture from the time when they got the way into the top social class in the name of making an achievement.Emperor Gao of Southern Qi had made great achievements in classics and history and literature and arts.He attached great importance to the education of his descendants,forming a good cultural atmosphere in his family,so most of them achieved a lot in academic study and literature.Even in the Liang Dynasty they still composed some prominent writings.Moreover,Xiao′s sons had the scholarly characteristics in their temperament and likings,for instance,the emphasis on appearance and manner and love of antiques.All witnessed their quickening of the scholarly tendency after they got power.


We design AssureMR, a system that supports efficient verification of SQL Selection-GroupBy-Aggregation (SGA) query evaluation on an untrusted MapReduce system. AssureMR does not rely on a centralized trusted party to construct the authentication data structure (ADS). Instead, AssureMR allows the untrusted mappers/reducers to construct ADS. AssureMR provides the following verification functionality: (1) correctness verification of ADS; (2) correctness verification of intermediate query results by individual mapper; and (3) correctness verification of final query results by reducers. Our experimental results demonstrate the efficiency and effectiveness of AssureMR.


This article intends to present the procedural system as a coordination mechanism of State action, which fits within the separation of powers, and it is a response to the paradoxical cases arising from post-modern society. In this way, the limits of constitutional law resulting from post-modern complexity will be presented, along with the problem of paradoxical cases, which are not those called "hard cases", and the paradigm of proceduralization as a measure of contemporary constitutional democracy. In addition, the stages and aspects of social structural construction that have built post-modern society will be presented, and that have raised the social problems of litigious cases, whose Judiciary has full capacity to decide them, to undecidable cases, especially with the process of extinction of metanarratives and the transition from the society of organizations to the society of platforms.


OBJECTIVE
Determination of left ventricular function, in patients with ventricular inhibited (VVI) and atrioventricular universal (DDD) pacemakers, by measurement of systolic time intervals.

DESIGN
Twenty six patients were studied (six with DDD pacemakers and twenty with VVI pacemakers). In all of them systolic time intervals measurements were obtained the day before and one week after the implant.

PATIENTS
We have studied twenty six patients consecutively, and all of them completed the study.

INTERVENTIONS
The measurement of systolic time intervals was obtained, by the simultaneous recording of ECG, phonocardiogram and carotid arterial pulse. The recordings were obtained at a paper speed of 100 mm/sec.

MEASUREMENTS AND RESULTS
The values obtained before the implantation were similar in both groups, but one week after implantation they show a closer to normal ventricular function, in patients with DDD pacemakers.

CONCLUSIONS
The measurements of systolic time intervals, is a very easy method, to determine left ventricular function non invasively. In patients with DDD pacemakers, the left ventricular function, was better than in patients with VVI pacemakers.


This paper discusses the factors which govern the intelligibility of speech sounds and presents relationships which have been developed for expressing quantitatively, in terms of the fundamental characteristics of speech and hearing, the capability of the ear in recognizing these sounds. The success of the listener in recognizing and interpreting speech sounds depends on their intensity in the ear and the intensity of unwanted sounds that may be present. The relationships presented in this paper deal with the intelligibility of speech sounds as a function of these intensities in the different frequency ranges of speech. Results calculated from these relationships are compared with observed results for a variety of systems.


This paper explores the spiral curriculum with particular reference to higher education and within the business related degree programmes. An initial literature engagement highlights sources which are key to understanding the spiral curriculum in university education. Further literature analysis critically examines and demonstrates the higher education consistency of the spiral curriculum with other university relevant pedagogies/andragogies namely the longstanding cognitive domain taxonomy and the developing threshold concepts paradigm – including and especially in context of business related studies. Drawn in part from the literature analysis, this paper then puts forward a typology for classification of the revisiting aspect of the spiral curriculum, here termed DUPE (Deployment, Underpinnings, Practice and Examination). The sense-making and simplifying value of this typology is indicatively explored, alongside the above stated paradigms, through primary research interviews with a selection of core module (marketing, finance/accounting, people management/ organisational behaviour) business tutors from a UK higher education provider. Despite sample limitations in terms of single institution focus and lack of research on students' experience, findings strongly indicate that; a) the spiral curriculum revisiting process fits within effective business degree delivery; and b) neither the DUPE typology nor the threshold concepts paradigm supersede the cognitive domain taxonomy as a simplifying sense-making depiction approach of that revisiting, but that both add explanatory value as to the way in which the spiral curriculum revisiting takes place.


We develop a combinatorial polynomial-time algorithm to make a (k − 1)-connected digraph k-connected by adding a minimum number of new edges. In [7] a min-max theorem was proved (in a more general form) for the minimum number of new edges whose addition makes a (k − 1)-connected directed graph k-connected. In this paper we describe a new, constructive proof that gives rise to a combinatorial polynomial-time algorithm.


The photosynthetic rate,stomatal conductance and water potential of fourteen exotic garden species in Baotou were measured.The results indicated that the net photosynthetic rate water potential compensation point and the water potential at the critical variety point of stomatal conductance could be considered as the adaptability indexes for trees to water stress.According to the net photosynthetic rate water potential compensation point,the water potential at the critical variety point of stomatal conductance and osmotic potential at the initial loss turgor,the tested species were classified as five kinds by cluster analysis.The drought resistance(from strong to weak) of the tested species was showed as follows: Spiraea×bumalda 'Gold Mound';Spiraea×bumalda 'Gold Flame',Ligustrum obtusifolium,Acer negundo 'Kellys Gold',Philadelphus coronaries 'Aurea';Physocarpus opulifolius 'Darts Gold',Prunus×cistena 'Pissardii',Acer negundo 'Aureo-marginatum',Acer negun do 'Variegatum';Sambucus racemosa 'Plumosa Aurea',Weigela florida 'Ziye',Caryopteris×clandonensis 'Worcester Gold',Weigela florida 'Variegata';Weigela florida 'Red Prince'.


In this paper, a new charge pump architecture is presented: it is based on PMOS pass transistors with dynamic biasing of gates and bodies. By controlling the gate and body voltages of each pass transistor, the voltage loss due to the device threshold is removed and the charge is pumped from one stage to the other with negligible voltage drop. Furthermore, the overdrive voltage of the pass transistors grows progressively from the first to the last boost stage. This new architecture was developed and validated through simulations and experimental measurements on AMS 0.8/spl mu/m standard CMOS technology.


An analysis of the levels of air pollution in Urumqi shows that there were three kinds of inhalable particles in the main pollutant in Urumqi:PM10,SO2 and NO2,whose density showed heating periodnon-heating periods.PM10 of heating period,surpassing the set standard was 1.74 times,standard of SO2 was 1.45 times,but NO2 was the lowest which reached the standard during heating period and non-heating period.The winter was the most seriously polluted season.The most seriously polluted weather accounted for 7.5 days of Jan.and 5.3 days of Oct..The pollution index in south part of Urumqi was higher than that of north part of it.The pollution in atmosphere of Urumqi were mainly caused by topographical factors such as low wind velocity in winter,thick inversion layer,strong stabilization of atmosphere.The atmospheric pollution caused by a great amount of power supply,heating supply,heat supply in long winter.A great amount of pollutant were discharged from Urumqi.The system of heating supply,heat supply,power supply were too close to the center of Urumqi city and there were a great population density in the center of city.


the detailed discussion of an Epicurean thesis follow a general consideration of the problem it was designed to solve. Thus he introduces Epicurus' epistemology as a theory opposed to the 'a priori rationalism' of Plato: both philosophers regarded sensation as &\oyo<:, but for Epicurus, Pesce argues, this was essential to its validity as a criterion of truth. The function of reason in his system is not to grasp a priori truths but to attend to the indubitable data provided by the senses. Pesce's analysis of Epicurus' theory of knowledge is impressive; but he does not discuss the problem of how we are to be certain that our view of something is ivapyfis. It seems fanciful to suppose that there is any link between Epicurus' use of eXSw\oi> and Platonic ei6o<r, p. 27. Pesce's comparisons between Plato and Epicurus are most helpful when they cover general principles: 'for Plato science is a system in which logical form and intelligible content tend to make a unity while for Epicurus it is a collection of facts united by the method of explanation', p. 19. The strengths and weaknesses of the book are also evident in the fourth chapter, 'Ontologia e cosmologia'. Pesce's treatment of controversial details such as the 'swerve' is perfunctory and strangely neglectful of Lucretius. But he again casts an interesting light on certain Epicurean concepts by viewing them against a Platonic background. In particular he draws attention to the orderliness of the Epicurean universe in which indestructible atoms possess intrinsic form and have determinate movement as one of their properties. The contrast with Platonic cosmology in the Timaeus is striking, irrespective of whether Epicurus had Plato as his principal opponent. Italian scholars have always found Epicurus a congenial subject and this book is no exception. Pesce never loses sight of the fundamental principles of Epicureanism and it is remarkable how much he succeeds in saying within a very limited space. At times he writes too much as an apologist and he does not indicate the difficulties which affect the interpretation of so many details in Epicurus' system. But his book has a vigour and conceptual range which make it one of the best short treatments of Epicurus.


The purpose of this paper is to investigate the possibility of using a feedback PD compensator for disturbance rejection associated with delayed double integrating processes. The MATLAB optimization and control toolboxes are used to tune the PD compensator using five error-based objective functions. The best objective function for this control application is assigned. The effect of the process time delay on the performance of the control system during the process of disturbance rejection is investigated. The effectiveness of using the feedback PD compensator is quantitatively evaluated.


In this study, the genetic algorithms and fuzzy comprehensive evaluation were used together to analyze the product assessment data. It is explored which operators were employed and whether everybody used the same operators in fuzzy comprehensive evaluation. It investigated the evaluation made by undergraduates on Master Kong beef instant noodle. The results demonstrated that males used the "max min" compound operator. Females used the "limitary sum min" compound operator. The research shows that genetic algorithms-based fuzzy comprehensive evaluation is useful in the data analysis for instant noodle assessment.


Photolysis of [Cr(CO)6] in the presence of BH3·PMe2CH2PMe2·BH3 (2) afforded a dichromatetraborane derivative [{(OC)4Cr}2(η4-H,H',H'',H'''-BH2BH2·PMe2CH2PMe2)] (3) via an intramolecular dehydrogenative coupling of BH3 units on the metal. The complex 3 can be depicted as a dichromatetraborane derivative, with the wing-tip BH2+ groups in tetraborane(10) replaced by Cr(CO)4 fragments, which are isolobal with BH2+, and the terminal hydrides attaching to the basal boron atoms replaced by isoelectronic phosphine ligands.


The purpose of this study was to determine the effect of managerial ownership on firm value through the linear and non-linear approaches. This study was conducted on 54 observations which included the Indonesian Most Trusted Companies in 2008 until 2011. The results of this study showed that managerial ownership does not have a linear effect on the firm value, but have non-linear effect on the firm value. Turning point in the managerial ownership were 3.36% and15.15%. At ownership of 0%-3.36%, it may cause a decrease in the value of the company (entrenchment effect) while 3.36% to 15.15% ownership may result in an increase in the value of the company (alignment effect)


Abstract. The enhanced conductive lauric acid (LA) phase change material was prepared with expanded graphite, aluminum powder and carbon fiber as the thermal conductive filler and its thermal properties were tested and analyzed. The results show that expanded graphite, aluminum powder and carbon fiber thermal filler in LA phase change material does not greatly influences LA phase change temperature. The phase change temperature of the LA phase change material is between 45°C -45.9°C when the mass fraction of thermal conductive filler is 2%, 5%, 10% and 20% and the LA / EG composite phase change material has a low "leakage" threshold. The thermal conductivity reached 1.478 W/m∙K when the EG mass fraction reached 30%. In addit ion, thermal control system of solar cells was designed using LA / EG phase change material as the thermal control material, and the experimental research on optimal configuration of solar cells and phase change material was carried out. The results show that phase change material has obvious control effect on solar cell temperature, reducing the temperature by 7°C.


Seemingly persuasive arguments can be made to suggest that income from foreign-owned capital should be taxed by a small open economy and that it should not be taxed. The author shows that the case for taxing foreign capital income as part of an "optimal" tax scheme rests on the assumption that tax rates on other forms of income are not set optimally. In particular, if economic profit is not fully taxed, a tax on foreign capital income should not be taxed by the capital-importing country. Copyright 1992 by The Economic Society of Australia.


To reduce the skyrocketing energy consumption of data centers, the prevailing approaches adopt the time-driven manner to control IT and cooling subsystems. These methods suffer from highly dynamic system states, complex action spaces and the risk of instability caused by frequent and unnecessary control operations. To tackle these problems, we propose a novel event-driven control paradigm and an optimization algorithm, under the deep reinforcement learning (DRL) framework. The principle is to make decisions based on certain critical events (e.g., overheating), rather than fixed periodic control. Specifically, we design an event-driven optimization framework to trigger control operations. Then, we present several models to describe IT and cooling subsystems, and mathematically define events to capture four types of prior factors that impact system performance. Furthermore, we develop an event-driven DRL (E-DRL) optimization algorithm to dispatch jobs and regulate cooling facilities for energy efficiency. Using two different types of real workload traces, we conduct extensive experiments to demonstrate that: 1) E-DRL reduces the number of regulating decisions by 70%<inline-formula><tex-math notation="LaTeX">$\sim$</tex-math><alternatives><mml:math><mml:mo>∼</mml:mo></mml:math><inline-graphic xlink:href="hu-ieq1-3157145.gif"/></alternatives></inline-formula>95% while achieving a comparable or even better energy efficiency in comparison with the state-of-the-art algorithm; and 2) E-DRL can adapt the control frequency to the changing operational conditions and diverse workloads.


We have analyzed the effect of planting site (elevation) and direction of fruiting on the frost damage (tolerance to transparent skin and blemishes) of persimmon (Diospyros kaki Thunb) 'Fuyu' fruit subjected to the early fall frost (November 2, 2012) in environment-friendly orchards of Changnyeong and Changwon (Gyeongsangnam-do Korea). In Changnyeong, the direction of fruiting showed a significant effect on the fruit weight and the fruit width (p<0.01), and the fruit firmness (p<0.05) while the planting site (elevation) did a highly significant effect on the fruit width and the frost damage (p<0.01), and fruit length (p<0.05). In particular, severe frost damage of fruit (15.2%) and leaves (about 90%) was observed in the plants located in the low elevation area of orchard. The damaged fruit had an transparent skin color and/or blemishes. In Changwon, there was no effect of the planting site and the direction of fruiting on the frost damage, and the fruit characteristics except the fruit width having been related to the planting site (p<0.05). So, the main effects for the fruit frost damage was a terrain factor around the orchards.


The idea of a simple volumetric cylindrical cloak, based on a pile of stacked transmission-line-based layers, is presented. Each layer comprises a previously introduced web-like transmission line network, sandwiched between two parallel metallic plates without any matching layer. Full-wave simulations showed a decrease of the scattered field, i.e the existence of a cloaking effect. However, the cloaking effect was deteriorated by the existence of a parasitic TEM mode within parallel metallic plates. A method of compensation of this effect by connection of a lumped reactive load at the edge of metallic plates is proposed.


A series of Michael acceptors based on a coumarin moiety, were developed as fluorescent probes for ratiometric detection of in vivo glutathione. The α,β-unsaturated Michael acceptors were transformed into non-conjugated molecules through the Michael addition of biothiols. The resulting UV-vis and fluorescence spectra of the probes revealed characteristic ratiometric responses, which were successfully applied for the multichannel imaging of in vivo glutathione.


A small medium micro  enterprises  is the most resistant to the economic crisis as a small business is able to survive in the mid business high competition . In the era of free trade Small Medium Enterprises (SMEs) into alternative buffer belt of the nation's economy. In a free market opens  a challenge and an opportunity that is very promising for the development of SMEs in Batam. As a business unit, SMEs in view of need to increase the capacity and competitiveness of SMEs fellow in Batam as well as in other areas. Positive competition among SMEs will encourage owners of capital to innovate and inculcate product shares towards business opportunities that allows rapid turn-around of their money back. Product quality challenges ahead in order to compete with foreign products which entering the country. In business development, promotion is an effective tool for introducing the product. Further interest in the promotional products market is done will be the target for Entrepreneurs. So it is important for business owners are to choose the right promotional media. Radio is one of the effective promotional tools. In the development of SMEs, selecting a local radio as a promotional tool which effective and affordable. Radio broadcasting as a frequent media interface in the everyday life (Prayudha, 2004). Radio is expected to not only provide entertainment, but also can provide information that can be received and used the audience for productive activities, while enhancing public knowledge, so that by itself is expected to be more critical of community development program. This is increasingly important in line with the more intense attempts utilizing radio as a means of communication and media development in Indonesia. Radio program not merely convey information, but can be interesting, even indirectly to direct the behavior of the audience. Therefore, the radio can be used as promotional tools that play a role in improving public services. With the assistance of an interesting narrative advertisement or promotion of the product in the form of talk shows, SMEs as businesses will benefit by using the radio as a promotional tool. When acting as a resource whose role is to provide information to the public services, SMEs must be able to meet the needs of listeners, so the impact on the listener satisfaction for SMEs services. Radio through specific programming also serves as a place to collect and convey the needs of the market for the SMEs' products.


A technological method for erecting suspended formwork was rationally designed, combining the travelling formwork used in road and bridge construction with the construction of main girders in high pile berths The newly designed technological method is of valuable reference for the construction of high pile wharves in areas with low tidal ranges


In 1958, Heather (1) reported on a 2-year follow-up of patients admitted to the Rehabilitation Center of the Hospital of the University of Pennsylvania. His report covered 1954 and 1955, the first 2 years of operation of this facility. The present study is an extension of that of Heather. The data included in this report pertain to a statistical analysis of various aspects of admissions, results of treatment, and follow-up information, for the years 1954 through 1958. It is our hope that, by retrospective study, we may learn how to improve our techniques so that we may offer better care and training to those who are disabled. The Rehabilitation Center involved in this study is an 18-bed unit which provides the services of the physiatrist, physical therapist, occupational therapist, social worker, speech therapist, nurse, psychologist, vocational counselor, and psychiatrist. In addition, as a unit of the Hospital of the University of Pennsylvania, consultants in all of the medical and surgical specialties are available on request. The diagnostic services of the various testing laboratories and the x-ray department are utilized as indicated. Each patient was admitted to the center for a pre-determined period of time, depending upon need. Some were admitted primarily for evaluation, some for definitive treatment. What kinds of patients were admitted and how these patients benefited from our program wil l be shown in this study, We will discuss our findings in two sec-


A thesis submitted to the school of graduate studies of Addis Ababa University, College of health science, school of allied health science, department of nursing and midwifery in partial fulfillment of the requirements for the degree of masters in child health nursing


Attractive faces have reward value for beholders, and thus people are motivated to view them. The incentive salience of attractive faces has been measured by using a pay-per-view key-pressing paradigm, wherein participants change the viewing time of a presented face image. For example, it was reported that male and female viewers were motivated to view attractive opposite-sex faces and cute infant faces longer than less attractive/cute faces. However, sex differences in the motivation to view attractive adult and cute infant faces were equivocal. We replicated previous observations from Caucasian populations that attractive faces are viewed longer than less attractive faces in a pay-per-view task in East-Asian populations. Results revealed that our male and female Japanese participants both made efforts to view attractive/cute faces irrespective of face category.


Let $K$ be a an algebraically closed field with $\operatorname{char}(K)\neq 2$, and $A$ a skewed-gentle $K$-algebra. In this case, Crawley-Boevey's description of the indecomposable $A$-modules becomes particularly easy. This allows us to provide an explicit basis for the homomorphisms between any two indecomposable representations in terms of the corresponding admissible words in the sense of Qiu and Zhou. Previously (Geiss, 1999), such a basis was only available when no asymmetric band modules were involved. We also extend a relaxed version of fringing and kisses from Br\"ustle et al. (2020) to the setting of skewed-gentle algebras. With this at hand, we obtain convenient formulae for the E-invariant and g-vector for indecomposable $A$-modules, similar to the known expressions for gentle algebras. Note however, that we allow in our context also band-modules. As an application, we describe the indecomposable, generically $\tau$-reduced irreducible components of the representation varieties of $A$ as well as the generic values of the E-invariant between them in terms tagged admissible words.


The singlet and triplet states of cyclobutenylidene 1 and benzocyclobutenylidene 2 have been studied computationally (using ab initio and DFT methods) in order to assess the effect of angle strain on the S-T gap of vinyl-and phenylcarbenes. It is found that both carbenes have a singlet ground state. Cyclobutenylidene 1 has a more significant singlet-triplet gap (-25 kcal mol - 1 ) than benzocyclobutenylidene 2 (-14.5 kcal mol - 1 ). The strong preference of 1 for a singlet ground state may be understood if it is viewed as bicyclobut-1-ene with a considerably puckered ring. Singlet benzocyclobutenylidene ( 1 2) is computed to have also a puckered cyclobutene ring albeit less pronounced. The lowest isomerization path available for singlet cyclobutenylidene ( 1 1) is the formation of vinylacetylene, which is predicted to have a barrier of around 9 kcal mol - 1 . Our calculations suggest that singlet benzocyclobutenylidene ( 1 2) lies in a rather deep potential well and should be observable under suitable experimental conditions. However, under low-temperature Ar matrix conditions no evidence for the formation of carbene 2 was obtained from the photolysis of precursor 15. On the other hand, laser flash photolysis (LFP) of precursor 16 enables us to observe benzocyclobutenylidene at room temperature. The lifetime of carbene 1 2 is determined to be 0.6-0.7 μs in cyclohexane. The m C X Y value for carbene 1 2 is determined to be 0.43, revealing a strong electrophilic nature and ranking 1 2 second among the electrophilic carbenes listed in the carbene philicity spectrum.


The Market and Technoscience represent a deep horizon, within which the ambit of human experience is unveiled. Technoscience has become the human horizon of understanding with respect to the world and the individual 1 0 .1 7 7 7 1 /P U C R io .A T eo .2 6 6 4 5


Considering the promising antitumor effects of compounds with dual anti-inflammatory and antiproliferative activities, thus benzophenones analogs (2-7) were evaluated on in vivo antiinflammatory assay and molecular docking analysis. Those with the best molecular docking results were in vitro evaluated on cyclooxygenase (COX) enzymes and tested regarding antiproliferative activity. All derivatives displayed in vivo anti-inflammatory activity. Among them, the substances 2'-hydroxy-4'-benzoylphenyl-β-D-glucopyranoside (4), 4-hydroxy-4'-methoxybenzophenone (5) and 4'-(4''-methoxybenzoyl)phenyl-β-D-glucopyranoside (7) showed the best values of Glide Score in COX-2 docking evaluation and 4 and 5 selectively inhibited COX-2 and COX-1 in vitro enzymatic assay, respectively. Thus, 4 and 5 were tested against breast cancer (MCF-7, MDA‑MB-231, Hs578T) and non-small-cell-lung cancer (A549) cell lines. The estrogen-positive MCF-7 cell line was more responsive compared to other tested cell lines. They induced cell cycle arrest at G1/S transition in MCF-7 cell line once there was an increase in G0/G1 population with concomitant reduction of S population. The antiproliferative activity of these substances on MCF-7 was associated with their ability to inhibit cyclin E expression, a critical regulator of G1/S transition. Taken together, the data indicate that 4 and 5 have dual anti-inflammatory and antiproliferative activities and support further studies to evaluate their antitumor potential.


The faulted feeder selection and fault identification under the condition of single-phase earth fault in the neutral un-effectual grounded system (NUGS) has long been a problem. As a matter of fact, existing methods that have been proposed may face some difficulty in the case of some scenarios, as the impact of the Petersen coil must be taken into consideration, or when the accurate location of the faulted point is required and the zero-sequence current cannot be measured. To against this, a novel faulted section identification method based on the transient current distribution is put forward by means of theoretical analysis and simulation study. It is shown by the results that this methods can give accurate location of the fault by comparing the transient RMS value of the upstream and the downstream of the fault point, even though the Petersen coil is switched in.


High peak-power picosecond laser pulses have been used for the first time to effect nonresonant or resonant multiphoton ionization (MPI) of clusters generated in a supersonic nozzle expansion. The resulting ions are subsequently detected and characterized by time-of-flight mass spectroscopy. Specifically, we present results involving MPI of clusters of xenon and nitric oxide. Previous MPI studies of many molecular clusters using nanosecond lasers have not been successful in observing the parent ion, presumably due to fast dissociation channels. It is proposed that the present technique is a new and rather general ionization source for cluster studies which is complementary to electron impact but may, in addition, provide unique spectroscopic or dynamical information. 23 refs., 5 figs.


The grouping of people in densely populated areas indicates the use of monitoring systems of remote sensing and spatial analysis with Geographical Information Systems. In this study, the impervious surface of the city of Sao Carlos, Sao Paulo State, was studied during a period of 44 years using of aerial photographs and Landsat 5 satellite images and ALOS. Statistical analysis was used for modeling, which allowed the prediction of population growth and the impervious surface by the year 2050. The results show that compared to 2006, estimates for 2050 are from a population of approximately 382,385 people (+76.8%), and a impervious surface of 143.1 Km² (+93.6%). This analysis suggests that population density will continue to decrease due to the development of new areas, which indicates dispersion of city, resulting in a higher area consumption by increasing the pressure on the surface and underground water sources. Thus, we conclude that the integration of technical and legal effect of land use planning is of great importance for the maintenance of hydric resources.