This expert panel is the second of a two-panel series marking the 40th anniversary of "Cognitive Systems Engineering: New Wine in New Bottles" by Hollnagel and Woods (1983) and, arguably, the beginning of Cognitive Systems Engineering (CSE). These experts were there at (or near) the beginning. They wrestled with the daunting issues of how to apply new CSE findings, many of which they themselves discovered, into workable solutions that actually improved systems performance in high-uncertainty, high-stakes settings. Their work has been implemented in a number of fields, including aviation, healthcare, power generation, and defense. They will each answer the question, "What ideas and perspectives are important about Cognitive Systems Engineering, and why?"


Part I. Neurotransmitter Release: 1. Mechanisms of exocytosis and the central role of calcium 2. Co-transmission 3. Models and mechanisms of neurotransmission Part II. Modulation of Neurotransmitter Release: Basic Principles and Key Players: 4. Modulation of neurotransmitter release 5. Modulation by autoreceptors 6. Modulation by heteroreceptors 7. Modulation by hormones and local tissue factors 8. Modulation by corticosteroid hormones Part III. Modulation of Neurotransmitter Release: The Cellular Mechanisms Involved: 9. Second messenger pathways in the modulation of neurotransmitter release 10. Regulation of calcium influx as a basis for modulation 11. Calcium-independent modulation Part IV. Modulation of Neurotransmitter Release: Physiological Function: 12. In vivo evidence for presynaptic modulation 13. Modulation of secretion from neurosecretory cells Part V. Modulation of Neurotransmitter Release: Clinical Relevance: 14. Possible role of presynaptic receptors in hypertension 15. Monoamine neurones and antidepressant treatments 16. Modulation of neurotransmitter release by some therapeutic and socially-used drugs 17. Beneficial therapeutic interventions via manipulation of presynaptic modulatory mechanisms.


A full chip mixed-signal simulation method has been presented. An all Verilog simulation engine verified a 16-bit pipe-lined ADC design for functionality and noise performance. Fast simulation times and high accuracy were achieved using Verilog models for analog components and noise.


This dissertation aims at studying the two French translations of Carson McCullers's 1946 novel The Member of the Wedding, and additionally offers a more recent and personal vision of this novel with the translation of an excerpt from the novel. The present translation study was completed with a stylistic approach of the novel and of the official translations, thus taking into account the narrative devices, the grammar and the literary style of the novel. The main objective of this dissertation is to prove that themes like the main character's loneliness, physical difference and potential sexual ambiguity (the main character is Frankie Addams, a pre-adolescent girl from the South of the United-States) were not only quite ahead of the novel's time of publication, but they are especially present in the author's writing style and thus introduce important challenges for the French translation. Indeed a good translation would have to consider the stylistic and narrative nuances of the present novel in order to account for the intrinsically "queer" atmosphere of the novel at best.


This paper considers the upper bound estimate of second eigenvalue with general weight for the differential operator with any order.The inequality of upper of second eigenvalue is deduced from first eigenvalue by using testing function,Rayleigh theorem,partial integration and Schwarz inequality.The estimate coefficients do not depend on the measure of the domain in which the problem is concerned.The result is widely used in physics and mechanics,and it plays a significant role in the research of differential equations.


The article begins by pointing out the requirements placed on the dynamics of measurement due to advanced computing techniques and automation engineering. This is followed by a survey of basic terms such as root mean square deviation and other error definitions, their correlations and interpretations with the aid of modern geometry in Euclidean and non-Euclidean spaces. Relations between data storage and measuring errors are shown by use of the findings of the information theory. Furthermore, methods for the analysis and synthesis, i.e. optimisation of measuring systems are discussed.


In spite of the great quantities of bronze f7om prehistoric times recovered during excavations, relatively feeo$nds of the main alloying element, tin, which would be required for addition to the copper base, have occurred. This phenomenon is examined in some detail, with the conclusion that trade, and addition to copper, could have been as cassiterite or other tin-bearing minerals which may not have been recognized and recorded by excavators in the past. Various forms of cassiterite and other possible tin-bearing additions are described and illustrated and methods of ident8cation outlined in order that excavators dealing with hoar& or smelting sites may be aware of significant material. Dr Charles, Fellow of St John's College, Cambridge, and Lecturer in the Department of Metallurgy and Materials Science of the University of Cambridge, has written for us befoe (1968,278; Xg70,207; Xg72,~34).


Objective To investigate the influence of behavioral nursing to medication adherence in the elderly hypertensive patients,and to provide reference for clinical.Methods 360 elderly hypertensive patients in our hospital between June 2009 to June 2011 were divided into observation group(180 cases)and control group(180 cases)randomly.The patients in control group were given routine medicine therapy only,and the patients in observation group received behavioral nursing on the basis.The medication adherence according to Morisky-Greenand Scale and blood pressure control effect were compared after 6 months between 2 groups.Results After 6 months treatment,the excellent or good rate of medication adherence was 77.8% in observation group and 54.4% in control group;the rate of hypertensive control was 72.2% in observation group and 43.3% in control group,all differences have statistical significance(P 0.05).Conclusion The behavioral nursing can improve medication adherence greatly and control hypertensive effectively in elderly patients.


In this study, the developments of hydroelectric power plants (HEPP) have been investigated. This type of plants plays a role in electricity generation substantially greater than any other renewable and sustainable energy resources. For this purpose, development of the power plant has been investigated in worldwide, national and region of Kahramanmaras scale respectively. Especially hydroelectric power plant in Kahramanmaras has been separately analyzed according to the type of operating and planning compared with Turkey. The result of comparison is given as a table. Comparison shows that, HEPP in the Kahramanmaras supply to the total hydro power in Turkey as a range of 5.59%


This text mainly combines the rigorous situation that the current resources of water lack,basing on building plumbing,to put forward some viewpoints and suggestions of plumbing desgin,for reducing the invisible waste of the resources of water,economizing the water.


The integrity of wind power output data is of great significance for the accurate prediction of wind power and the utilization of wind energy. In this paper, it is found that the power output affected by many factors, through the analysis of the mathematical model of wind turbine, and the solution of the specific expressions of the relationship with the traditional mathematical methods is hard to find. Based on the measured data of wind field, such as fan current, rotor speed, wind direction, and so on, a kind of model based on adaptive BP neural network is proposed to fill the missing wind power data. The simulation experiment shows that the accuracy rate and the average relative error of complete data get better results, besides the quality of completed data is improved effectively.


(Abstract )Data missing is a common problem in data mining and data analysis process, it can lead to reliable decisionmaking if it is deleted with the cases directly. An imputation method of solving the missing data is put forward, which is based on association rule. In this method, the rules are classified by the rules' consequent, and then calculate the similarity of constrained rules cases' items and missing cases' items, impute the missing value with the most similar rule's item. Experimental results show this method has higher imputation accuracy. (Key words )association rules; missing data; imputation; neighbor rule; similarity; KNearest Neighbor(KNN) algori thm DOI: 10.3969/j.issn.1000�3428.2012.21.014


Human beings have two ears to localize sound sources. At a first glance, the dimensions of the right and left ears are generally very similar. Nevertheless, the individual anthropometric dimensions and shape of both ears are disparate. These differences improve localization on the cone of confusion where interaural differences do not exist. To determine the influence of asymmetric ears, individual HRTF data sets are analytically and subjectively compared with their mirrored versions.


A random walk model of a drainage network is generated on an underlying matrix by selecting at random the drainage direction out of the elementary areas. In a random roughness model, roughness heights of the elementary areas rather than drainage directions are assigned at random. The resulting topography of that model then uniquely determines the drainage pattern. An equivalence of the two models is suggested by the similarities, found in the mode of construction and by the equality of the probabilities of occurrence of some simple configurations. The random roughness model can yield values of primary probabilities, i.e., probabilities which can be used in the construction of a random walk model. The various types of drainage patterns are classified by the sets of primary probabilities which would generate them. Thus outcomes of homogeneous and isotropic matrices are classified as pure dendritic patterns. Outcomes of homogeneous matrices with probability sets derived from a sloping plane roughness model are classified as general dendritic (including parallel) patterns. Trellis, annular, and other patterns are considered as subgroups of the class of patterns generated on all other possible matrices.


Three experiments were conducted to determine the apparent (AID) and standardized (SID) ileal digestibilities of protein and amino acids (AA) in pea protein isolate (PPI), distiller's dried grains with solubles derived from a blend of wheat and corn (wcDDGS) and corn. In addition, two experiments were conducted to estimate the requirements of digestible sulfur amino acids (dSAA) and digestible lysine (dLYS) for 3week old broilers to obtain optimum growth performance (body weight gain, BWG and feed conversion ratio, FCR) and optimum yield performance (carcass yield, CY, breast meat yield, BMY, and thigh and drumstick yield, TDY). For digestibility studies, day-old male Ross 308 broiler chicks were fed test diets from day 1-14. The test diets were balanced for vitamins and minerals and contained chromic oxide (0.3%) as an indigestible marker. The protein and AA digestibilities were determined either by the direct or indirect method. For requirement studies, day-old male Ross 308 broiler chicks were fed lysine(Exp. 1) or sulfur AA(Exp. 2) deficient basal diets balanced for all other AA, except for the AA under test, according to the ideal protein concept. All test diets were also balanced for vitamins and minerals and were kept isonitrogenous and isocaloric within each assay. The average SID estimates of AA were 92.4%, 71.5% and 93.3% in PPI, wcDDGS and corn, respectively. Using regression analysis, the dietary dLYS requirement estimate was 1.12% and 1.13% for optimum BWG and FCR, respectively. The dietary dSAA requirement estimates was 0.81% for optimum BWG, while no significant response was observed for optimum FCR. Both CY and BMY


The newest stage of post-Soviet Eurasian economic integration associated with the large-scale tasks of making a breakthrough in the economic development of its participants, including the tools of the EAEU, imposes increased requirements for the content and quality of the integration agenda. At the same time, the imperative put forward by the governing bodies of the Union of compliance of the development goals with the operational objectives of maintaining the current macroeconomic stability of the Eurasian Union in the conditions of further growth of sanctions can no longer be a sufficient condition for the advanced development of the EAEU member States. In order to ensure economic growth at a faster pace of development and with a proper synergetic effect for the national economic complexes of the EAEU States, a fundamental basis in the form of a well-thought-out ideologically and structurally sound industrial policy is required.
In this context, the authors of the article touch upon such an essential element of the concept of this policy (the industrial policy of the EAEU, or the Eurasian industrial policy) as the criteria for jointly produced goods of the EAEU; an approach to its definition is proposed. Implementation of this approach, according to the authors, will create conditions for the development of mutually beneficial intra-Union production cooperation and import substitution, for a successful refraction to the post-Soviet realities of the relevant positive experience of the European Union.


Nitrogen‐containing steels have become an attractive material in industrial fields due to their excellent mechanical properties. Nevertheless, the current manufacturing methods to produce nitrogen steels are linked to technologies with high working pressures. Alloying elements such as Cr, Mn, and Mo enhance the solubility of nitrogen in the melt, which allows the production at atmospheric pressure. Herein, carbon–nitrogen martensitic steels are produced at low pressure (7 × 105 Pa). The composition is designed through the CALPHAD method using two carbon contents (0.7 and 1.3 wt%). The alloy is produced in an induction furnace under N2 atmosphere to mitigate desorption. Thermomechanical and heat treatments are performed. The alloys are analyzed using optical emission spectroscopy, X‐ray diffraction, optical microscopy, and scanning electron microscopy (SEM) with energy‐dispersive spectroscopy (EDS). The mechanical evaluation is conducted using hardness analysis. The steel presents a nitrogen content of 0.15 wt%, in agreement with the thermodynamic calculations. SEM and EDS results show the presence of Cr and Nb precipitates in a martensitic structure. The highest hardness values are obtained in specimens heat treated by tempering at 400 °C for 2 h and air cooling, achieving 57.4 and 59.7 Hardness Rockwell C for samples with 0.7 and 1.3 wt% C, respectively.


In the report of Eighteenth Congress of the Communist Party,we should speed up the reform of personnel development mechanisms and policy innovation,form the mechanism of stimulating talents with dynamic creation and international competitiveness,and create the situation of everyone show their living situation.This article focuses on personnel training and fair use.


Econometric evidence in EU competition law : a theoretical and empirical analysis / Ioannis Lianos and Christos Genakos -- The public enforcement of articles 101 and 102 TFEU under council regulation no 1/2003 : due process considerations / Arianna Andreangeli -- Public enforcement : the ECN -- network antitrust enforcement in the European Union / Damien Gerard -- Private enforcement in the EU with emphasis on damages actions / Assimakis Komninos -- Procedural aspects of merger control / Nicholas Levy -- The EU competition fining system / Damien Geradin, Christos Malamataris and John Wileur -- Competition law remedies in Europe / Ioannis Lianos -- EU competition law and private international law : a developing relationship / Barry Rodger -- Judicial review in EU competition law / Heike Schweitzer -- Relationship between EU competition law and national competition laws / Katalin Cseres -- Legal uncertainty, penalties, and the limits to effects : based standards / Yannis Katsoulacos and David Ulph.


The fight between the kings of imperial clan was lasting at the last phase of the Western Jin Dynasty, after the Min Emperor was captured by Liu Yao, Sima Bao and Sima Rui fought for the emperor seat, they all claimed themselves 'the Jin King'.In order to become himself the unique heir of the Jin Dynasty,Sima Rui did everything possible to collapse the strength of defence against the Northern barbarian in ancient China, which was the basis of the Sima Bao's Jin regime kept going, even by borrowing a knife from Duan Pidi to kill Liu Kun who was the main force of defence against the Northern barbarian in ancient China.The result of the fight was that Sima Bao became extinct under the Northern barbarian in ancient China's hard press,Sima Rui became the emperor who founded the East Jin Dynasty in Jiankang replaced the West Jin Dynasty in Luoyang.


One of the most unending debates in economics is whether financial development causes economic growth or whether it is a consequence of increased economic activity. The paper empirically examines the relationship between financial development and economic growth. In this study, the perceived relationship between financial development and economic growth is estimated econometrically using the Ordinary Least Square Estimation Method (OLSEM). The result showed that there is a substantial positive effect of financial development on economic growth in Nigeria. The Granger causality test showed that financial development promotes economic growth, but there is evidence of causality from economic growth to the development of financial intermediaries. Thus, advancement of the financial sector development, including diversification of financial instruments should be pursued to facilitate economic development in Nigeria.


Road safety is dirctly related to the overwhelming majority of the people's life and property safety,related to the coordinated development of the national economy,which has become a universal concern and an important social issue.This paper analyzes road safety situation at home and abroad,which aims at strengthening exchanges,ensuring safety and building a harmonious society.


It is necessary to set up the workpiece coordinate in numerical controlled machine fool processing as they are not concentric with the coordinates of a machine fool. Various ways to set up the workpiece coordinates in numerical controlled machine fool precessing are discussed in this paper.


A new technology of double steel cylinders for bored piles of Senbei Bridge is applied in case of construction at conditions with deep river, rapid flow, many passing boats and difficulty of cofferdam. Associated parameters are determined based on pressure analysis. Finally a brief introduction is given concerning the manufacture and construction of the steel cylinders.


This study is aimed at investigating the behavior of the autonomic nervous system (ANS) at sleep onset (SO) and to correlate it with higher brain activity captured as surface electroencephalogram (EEG). The study was performed on data obtained from 16 healthy subjects who underwent standard polysomnography (PSG). The instantaneous heart rate variability (HRV) provided a measure of ANS activity, and EEG was quantified by time-frequency analysis measuring power in alpha and delta frequency bands. The results revealed a power decrease in the VLF component of the inter-beat (RR) interval to a minimal level around SO, similar changes, though to a lesser degree in the LF component, and almost no change in the HF component. These changes correlated with a drop in alpha and a surge in delta EEG power. The sympathovagal balance, as reflected by LF/HF ratio, pointed towards an increase in the parasympathetic activity after SO.


In today's competitive world, and based on market economy along with rapid international changes and developments, entrepreneurship is considered as the engine of economic development that can play an important role in the country's economic growth, employment and social welfare. Puducherry formerly known as Pondicherry is a union territory of India. It was formed out of four regions of former French India, namely Pondichery (Pondicherry; now Puducherry), Karikal (Karaikal), Mahe and Yanaon (Yanam). It is named after the largest district, Puducherry. Historically known as Pondicherry the territory changed its official name to Puducherry in 2006. With many extensions, Govt.of Puducherry is taking lot of efforts to bring entrepreneurial growth in their regions. Creating awareness among students in Higher Education Institutions (HEIs) including rural colleges of Puducherry regions are tremendous. In order to motivate students youth force to turn around as entrepreneur is the prime objectives of the Entrepreneurial Development Cell (EDC), Govt. of Puducherry. It includes Start-up entrepreneurial activities, touch shop, idea generation programme etc., are taking place for influencing students' community to become as entrepreneur. This study aims to find out the most prominent factors affecting the entrepreneurial development among the rural college students in Puducherry region. For the purpose of the study primary data is collected from One Hundred students through structured questionnaire. The factors to be considered are Risk taking, Economic condition, Entrepreneurial training, and Family background, Confidence, Creativity and Innovation. Simple percentage method and Garett Ranking method were used. The finding of the study shows that Risk taking capacity, creativity and innovative skills are the most affecting factors in developing an entrepreneurship among the students in rural colleges of Puducherry region.


In the real world situations, many time series are aggregates of two or more time series. An aggregation may take place due to an addition or the product or both of two or more time series. We are often interested in the study of the properties of aggregates which are, in turn, dependent on the properties of the constituent series. Motivated by this problem, the authors study in this paper the properties of models generated by the operator (Σ+II) on autoregressive-moving-average (ARMA) processes of orders (pi,qi), i = l→n . A few practical examples where such models have been used are given in the introduction and an illustrative numerical example is discussed at the end of the paper.


OF THE DISSERTATION EXCHANGE RATE OVERVALUATION UNDER HYPERINFLATION: THE CASE OF PERU by Rafael Amiel-Saenz Florida International University, 1996 Professor Bruce R. Kelley, Major Professor This dissertation examines the behavior of the exchange rate under two different scenarios. The first one is characterized by, relatively, low inflation or a situation where prices adjust sluggishly. The second is a high inflation economy where prices respond very rapidly even to unanticipated shocks. In the first one, following a monetary expansion, the exchange rate overshoots, i.e. the nominal exchange rate depreciates at a faster pace than the price level. Under high levels of inflation, prices change faster than the exchange rate so the exchange rate undershoots its long run equilibrium value. The standard work in this area, Dornbusch (1976), explains the overshooting process in the context of perfect capital mobility and sluggish adjustment in the goods market. A monetary expansion will make the exchange rate increase beyond its long run equilibrium value. This dissertation expands on Dornbusch's model and provides an analysis of the exchange rate under conditions of currency substitution and price flexibility, characteristics of the Peruvian economy during the hyper inflation process that took place at the end of the 1980's. The results of the modified Dornbusch model reveal that, given a monetary expansion, the change in the price level will be larger than the change in the exchange rate if prices react more than proportionally to the monetary shock.


The paper introduces some of the latest automobile chassis technology,including BBW,ESP,AFS,RWS, ABC,CDC,FOUR-C,etc.,and expounds their structure components and basic working principles,and describes the development direction of chassis technology in the future.


enshrined in myriad national and international treaties1, there are still challenges for children with disabilities2 with regard to accessing education, being socially included in education and experiencing quality education. UNESCO identifies the disability prevalence rate in populations to be between 10 and 16 per cent3, yet the reported number of children with disabilities in schools is much lower (e.g. 1.79 per cent of total school enrolment in Uganda, 1.1 per cent in Rwanda and 0.7 per cent in Ethiopia). This indicates that a large number of children with disabilities are not in school4, or if they are, they are unidentified within current school populations. The challenge of inclusion for children with disabilities – experiences of implementation in Eastern and Southern Africa


This study encompasses the biodegradation capacity of Anabaena fertilissima to model PAH (Polycyclic Aromatic Hydrocarbon) compounds namely Anthracene (ANT) and Pyrene (PYR) at different LC50 concentrations viz., 5.0 mg/L and 3.0 mg/L, respectively, on growth in terms of Chlorophyll-a and protein. Depletion in chlorophyll-a and protein content was registered with rise in PAHs concentration while the inhibition of nitrogen fixing enzymes such as nitrate reductase and glutamine synthetase activity was also concentration dependent and showed more sensitivity for high molecular weight aromatic compound PYR as compared to ANT. GC/MS analysis explained the degradation of ANT by 46% and PYR by 33%, at 5.0 mg/L and 3.0 mg/L, respectively. Moreover, the common degraded product for ANT was 2, 4-Dimethyl-1-heptene and for PYR it was 2, 3, 4-Trimethylhexane. Results indicate that PYR was more stable and recalcitrant compared to ANT. This study suggests that Anabaena fertilissima could be used for bioremediation of ANT and PYR pollution in surface waters and terrestrial environments.


TEACHERS' PERSAONAL AND PEDAGOGICAL UNDERSTANDING OF PROBABILITY AND STATISTICAL INFERENCE Yan Liu Vanderbilt University firstname.lastname@example.com Pat Thompson Vanderbilt University firstname.lastname@example.com The purpose of this study is to develop an insight into teachers' personal and pedagogical understanding of probability and statistical inference. To this end, we undertook a teaching experiment with eight high school mathematics teachers. The teaching experiment was designed with the purpose of provoking the teachers to express and to reflect upon their instructional goals, objectives, and practices in teaching probability and statistics. Our results indicated that teachers had a complicated, inconsistent mix of meanings with regard to the ideas of probability, sampling distribution, hypothesis testing, and margin of error. STATEMENT OF PROBLEM Teachers' understanding of significant mathematical ideas has profound influence on their capacity to teach mathematics effectively (Ball & McDiarmid, 1990; Ball, 1990; Ball & Bass, 2000; Borko et al., 1992; Eisenhart et al., 1993; Simon, 1994; Sowder, Philipp, Armstrong, & Schapelle, 1998; Thompson, 1984; Thompson & Thompson, 1996), and, in turn, on what students end up learning and how well they learn (Begle, 1972; 1979). This has important implications for how teacher educators think about ways of supporting teachers' professional development—that supporting transformation of teaching practices takes careful analysis of teachers' personal and pedagogical understandings of what they teach. Probability and statistical inference are among the most important and challenging ideas that we expect students to understand in high school. They have had an enormous impact on scientific and cultural development since its origin in the mid-seventeen century. The range of their applications spread from gambling problems to jurisprudence, data analysis, inductive inference, and insurance in eighteen century, to sociology, physics, biology and psychology in nineteenth, and on to agronomy, polling, medical testing, baseball and innumerable other practical matters in twentieth (Gigerenzer et al., 1989). Along with this expansion of applications as well as the concurrent modification of the theories themselves, probability and statistical inference have shaped modern science and transformed our ideas of nature, mind, and society. Given the extraordinary range and significance of these transformations and their influence on the structure of knowledge and power, and on issues of opportunity and equity in our society, the question of how to support the development of coherent understandings of probability and statistical inference takes on increased importance. There have been many investigations of ways people understand probability and statistical inference. Psychological and instructional studies consistently documented poor understanding or misconceptions of these ideas among different populations across different settings (Fischbein & Schnarch, 1997; Kahneman & Tversky, 1973; Konold, 1989; Konold, Pollatsek, Well, Lohmeier, & Lipson, 1993a). The challenges for students are not associated merely with acquiring new skills but with overcoming ways of thinking that are unpropitious for reasoning probabilistically (Kahneman, Slovic, & Tversky, 1982; Konold, 1989, 1991) or for understanding probability as a mathematical model (Shaughnessy, 1992; Piaget & Inhelder, 1975), and dealing with the pervasive traditional teaching that works against efforts to make


Explosive bolt that has explosives in its body is separated into two bodies when explosives is exploding in its body. But sometiems despite of exploding of explosives it was not separated. The confinement condition is related to this phenomenon, so present work suggests the method for optimizing confinement condition of explosive bolt. By using data of pyro-shock, this study present best condition of confinement for separating of bolt numerically. The gap between explosive bolt and confinement is variable. It has been conducted many tests of explosive blots according to variable to know wether bolt was separated or not, and to get data of pyro-shock. It has been used computer simulation method to get analysis data, and we compared them with test data. The study presents the relationship between analysis data and test data. The present work is enable you to design of the best confinement condition by means of simulation of analysis computer program.


In this slim and simple volume the authors describe a system of medical care based on problem-orientated medical record (P.O.M.R.). They distinguish comprehensive care from the consultative care provided by specialists. Both are important, but when more than one doctor is involved in the care of an individual patient there is often a confusion of goals. To mini-nize this confusion an effective medical record is needed-one in which all of the patient's problems are systematically recorded and displayed. For Neelon and Ellis the problem-orientated record, introduced by Lawrence Weed, satisfies this need, and they assume that their readers also realize its. potential. In this book they describe how they use P.O.M.R., hoping to help others through the difficult process of effective implementation. Their text is clear and concise. They begin with excellent advice on the collection and recording of clinical data, on the formulation of problems, the preparation of the problem list, and on the construction of plans for the management of individual problems. The section on progress notes and flow charts, though short, is particularly good, and their advice, if followed, would reduce the bulk of clinical records and improve their quality. The authors consider the use of the problemorientated record in both an inpatient and an outpatient setting and show how, by coordinating the work of doctors and nurses, social workers, and others, the medical record can facilitate the team approach to the process of medical care. They reflect briefly on the educational power of the problem-orientated approach-for many people its greatest attraction. The authors have succeeded admirably in their purpose. Their book can be highly recommended to readers intending to introduce problem-oriented records and to those who are finding implementation difficult.


Protein folding in the endoplasmic reticulum (ER) is partly controlled by Protein Disulfide Isomerases (PDIs), which oxidise, isomerise and chaperone nascent secretory pathway proteins. The objective of this work was to characterise the expression, behaviour and localisation of a novel PDI homolog identified by in silico analysis.


but mostly, about her cunt, she pressed the papers, wadding and girding her fruitful organs, shutting her sex from view, and access. This was her assent, her husband's dream, and my containment. I was speaking of love, and America; and how I value it, as I knew you did, when you wrote: 'I want to be a woman to a man so badly, I can taste it almost.' I was speaking of value, I guess. Of what knits in the spaces, where wind creases its frigid movements into the face as it swerves on. I was speaking of you, and of love once more: warm, intelligenced, exacting; of more immanent value than Hebrew parallelism or the Anglo Saxon metre.


ABSTRACT
Objective: The aim of this study was to investigate the prevalence of bullying and victimization in high school students and the variation of bullying according to sociodemographic characteristics. Method: This descriptive study was conducted with 478 students in science and vocational high schools located on the same campus in the Eastern Black Sea Region. In the collection of the data, the approval of the governor, the approval of the ethics committee and the necessary consents were obtained. Data on "Assessing the Scale-Adolescent Peer Bullying Form" based on self-report using questionnaires and collected by face to face. In the analysis percentage, average, Kolmogorov-Smirnov test, one-way analysis of variance, t-test, Tukey test was used. Results: The average physical bullying; X = 1.67 ± 0.77, the highest mean and physical victimization to other peer bullying species; X = 1.87 ± 0.76 was found to be the highest compared to other types of victimization. It was found that 9th grade students were bullied and victims more than the other classes. According to students; bullying incidents occur in school areas with a maximum of 17.3%. Conclusions: Necessary guidance should be planned for the prevention of physical bullying and victimization throughout the school. Preventive and preventive measures should be taken for all 9th grade students who are the most bullied and exposed to bullying and the students staying on the board.


In Liu Xie holds that literature renders Tao by expressing sentiments;literary activity is indeed the process of rendering Tao by expressing sentiments,which therefore endows literary texts with significance.Literariness consists in the interaction of diction and sentiments.This interaction is the basic pattern that literariness originates.


The study on higher education of China has blazed a new path independently in recent 20 years.In the process from the big country to the great power in higher education study,we should smoothly deal with the following dialectic relations: the quantity and quality of higher education research,the theoretic and practical research,the research of past and present,and the research at home and abroad.


An electronic component, a manufacturing method thereof, a mounting structure of the electronic component, and a method for evaluating the electronic component are provided to reduce non-uniformity of contact resistance by increasing a ratio of an effective electrode with respect to a reference size to be higher than 10%. An electronic component includes a basic element(10) and a terminal electrode(20). The basic element includes at least one planar surface. The terminal electrode is formed on the planar surface of the basic element. The terminal electrode is electrically connected to a circuit board by using conductive particles. The planar surface serves as a reference surface. A ratio of a first projection size with respect to a second projection size of an outer surface of the terminal electrode is greater than 10%. The first projection size is obtained by projecting the outer surface of the terminal electrode on the circuit board. The second projection size is obtained by projecting the outer surface at a position higher than the reference surface by a value, which is obtained by subtracting a diameter of a conductive particle from a maximum height, on the circuit board.


Operators of event locations are particularly affected by a pandemic. Resulting restrictions may cause uneconomical business. With previous models, only an incomplete quantitative risk assessments is possible, whereby no suitable restrictions can be derived. Hence, a mathematical and statistical model has been developed in order to link measurement data of substance dispersion in rooms with epidemiological data like incidences, reproduction numbers, vaccination rates and test qualities. This allows a first time overall assessment of airborne infection risks in large event locations. In these venues displacement ventilation concepts are often implemented. In this case simplified theoretical assumptions fail for the prediction of relevant airflows for infection processes. Thus, with locally resolving trace gas measurements and specific data of infection processes, individual risks can be computed more detailed. Via inclusion of many measurement positions, an assessment of entire event locations is possible. Embedding the overall model in a flexible application, daily updated epidemiological data allow latest calculations of expected new infections and individual risks of single visitors for a certain event. With this model, an instrument has been created that can help policymakers and operators to take appropriate measures and to check restrictions for their effect.


Castings in plate form of commercially pure titanium KS50 and three titanium alloys, Ti-5Al-2.5Sn, Ti-6Al-4V, Ti-15Mo-5Zr, were prepared by using graphite molds and an arc skull furnace which was of tilting pour type with consumable electrodes, as previously reported. Mechanical and corrosion resistant properties of these castings were studied and compared with those of forged materials. In the case of KS50 and the α alloy, Ti-5Al-2.5Sn, there was no significant difference ofmechanical properties between the as-cast and the annealed castings. However, the strength of the α + β alloy, Ti-6Al-4V, in which phase stabilization occured during annealing, was increased by annealing. The hardening and the reduction of ductility due to ω phase formation in the Ti-15Mo-5Zr alloy castings were suppressed by annealing. There was no large difference of mechanical properties between castings and forgings of KS50. However, the Ti-5Al-2.5Sn alloy castings showed significant decrease of strength, compared to the forged materials, while the Ti-6Al-4V alloy castings showed slight decrease of strength and large reduction of ductility. The inferior properties of the castings seemed to be due to the large grain size. The presence of pin holes in castings of 0.5mm in diameter had a negligibly small effect on the tensile and smooth rupture properties. Annealing of the KS50 and the Ti-15Mo-5Zr alloy castings showed a small effect on the corrosion resistant properties which were, thus, comparable to those of the forged materials. α precipitates due to dendritic micro-segregation were observed in the Ti-15Mo-5Zr alloy castings and were not eliminated by the annealing treatment.


A 68-year-old woman presented with a five-month history of dry cough and intermittent fever. During the previous month, she had intermittent retrosternal chest pain radiating to her back. Two days before presentation, she had coughed up about 5 mL of blood on two occasions. She had type 2 diabetes


This is the documentation of five different studies to estimate the effects of an improved cycle route. All the studies were made as before and after studies. The purpose of the cycle route is to provide opportunities for road users to use a bicycle to a greater extent for journeys to work. Flows and speeds, bicycles: Measurements were made at nine points along the cycle route and at a control point outside the route. Measurements went on for five days, Monday to Friday, on three occasions before and on one occasion after the measure. Flows and speeds, motor vehicles: At two points on that part of the route that was situated in a street carrying mixed traffic, the flow and speed of vehicular traffic were measured. At one of these measurement points a cycle track has been constructed. At the other the bicycle route is still in the street carrying mixed traffic, but the speed limit on the street has been reduced from 50 to 30 km/h, and speed calming measures in the form of road humps have been installed in the street. Driving pattern - vehicular traffic on the street with 30 km/h and road humps: A floating car study was performed on that part of the cycle route which is still situated on a street carrying mixed traffic. Study of interaction between pedestrians and cyclists, a section of a combined pedestrian and cycle path: In order to measure the effect of segregating pedestrian and cycle traffic on a combined path, traffic was videoed before and after the measure. One indicator of a disturbed cyclist was identified. Study of interaction at junctions between a combined pedestrian and cycle path and mixed traffic: At three junctions measures were taken to improve the interaction between road users. The junctions were videoed, and the number of road users per path was noted on these films. For pedestrians and cyclists an assessment was also made whether they were disturbed by other road users. (A)


The essay discusses Fanny Fern's autobiographical narrative Ruth Hall (1854) in the context of  the emerging entertainment industry in antebellum America. A brief analysis of Fern's narrative  strategies, focusing on aspects of the characters' visual exposure, reveals that Fern's selfportrait as the "authentic" and independent Ruth Hall is in complex ways implicated in the very  mechanisms she purports to confront.


North American peatlands harvested for horticultural purposes remain dysfunctional when exploitation ceases, and need to be restored or reclaimed (Rochefort et al., 2003). The "Sphagnum moss transfer" technique has been developed for large scale restoration of cutover bogs, with the long term objective of bringing back these ecosystems to a functional state. From this perspective, restoration could only be considered a success if remains of new Sphagnum reached the catotelm without being decomposed totally in the acrotelm. Microbial recovery is delayed in comparison with vegetation establishment following restoration (Anderson et al., 2006) but as plants accumulate, fresh organic matter inputs might stimulate decomposition by micro-organisms (Glatzel et al. 2004) and compromise peat accumulation. We determined how surface vegetation and environmental conditions interact with the structure and activity of microbial communities in a gradient of increasing Sphagnum thicknesses found in cutover, restored and natural peatlands. We evaluated phospholipid fatty acid composition (PLFAs), decomposition potential, actual decomposition rates and we are currently assessing genetic diversity.


all cumulants of the magnetization. We find that ρ(�M ) ∼ �M −τ with an avalanche exponent τ = 1f or the SK model, originating from the marginal stability (criticality) of the model. It holds for jumps of size 1 � �M < N 1/2 , being provoked by changes of the external field by δH = O(N −1/2 )w hereN is the total number of spins. Our general formula also suggests that the density of overlap q between initial and final states in an avalanche is ρ(q) ∼ 1/(1 − q). These results show interesting similarities with numerical simulations for the out-of-equilibrium dynamics of the SK model. For finite-range models, using droplet arguments, we obtain the prediction τ = (df + θ )/dm where df ,d m ,a ndθ are the fractal dimension, magnetization exponent, and energy exponent of a droplet, respectively. This formula is expected to apply to other glassy disordered systems, such as the random-field model and pinned interfaces. We make suggestions for further numerical investigations, as well as experimental studies of the Barkhausen noise in spin glasses.


Microscopical, differential scanning colorimetry (DSC), and X-ray structural investigations of solution crystallized carbon nanotube (CNT) composites with linear polyethylene (LPE), isotactic polypropylene (iPP), polybutene-1 (PB-1), and nylon 6 (PA6) disclosed varying degrees of surface interaction and nucleation effect of CNT in these polymers and formation of oriented shish-kebab overgrowths on the CNT ropes in LPE and PA6. The character of the attraction and orientation forces at the CNT-polymer interface is discussed.


Paper presents the information transfer problem in the process of recognition of face images in biometric access control systems. The principle of the individual biometric verification system was considered. An algorithm for information converting during the process of person's verification by the image was presented. The learning algorithm for Hopfield neural network was considered. The two-dimensional Fourier transform was used to reduce the dimensionality of the input vector. The system based on the proposed algorithm has been implemented and tested. The proposed algorithm showed high accuracy and speed of execution. As part of the current problem the results are acceptable. Was detected that the results depend on the correct extraction of singular points, which in turn depends on the quality of the input image.


"Consider the less traveled path, because of the Jordan Curve Theorem" offers a basic introduction to simple, closed curves and explains why the theorem asserting that every simple closed curve in the plane separates the plane into an "inside" and an "outside" is best appreciated when considering pathological curves. A pathological curve, such as a space-filling curve or the Koch snowflake, is one that lacks features of so-called well-behaved curves. The discussion is enhanced by numerous hand-drawn sketches and a reference to "The Road Not Taken" by poet Robert Frost. Mathematics students and enthusiasts are encouraged to consider the less traveled path in mathematical and life pursuits. At the chapter's end, readers may check their understanding by working on a problem. A solution is provided.


This article examines the impact of the National Security Capability Review (NSCR) and Modernising Defence Programme (MDP) on the UK's existing strategic defence and security process. Andrew Curtis specifically assesses the appropriateness of conducting the NSCR and MDP discretely from the quinquennial Strategic Defence and Security Review process, and the consequences of undertaking them for defence reviews in the future.


Abstract Twenty-one multiparous Holstein cows in the late stages of their lactation period were used in complete randomized design to investigate the effect of rumen degradable protein on milk urea nitrogen (MUN) and some blood metabolites. Experimental periods were 6 weeks in length, with days 1 to 14 used for adjustment and weeks 3 to week 6 used for sampling (urine, blood, and milk). Three concentrations of a rumen-degradable protein (RDP) supplement according to National Research Council recommendations (9.3, 11.4, and 14% of dry matter intake) were treatments. Dietary RDP content altered both total urinary N and urinary N concentration, leading to increased urinary output. Estimations for microbial protein yield were compared with the measured excretion of purine derivative as yeast RNA equivalent, in urine. No significant effect of concentration of RDP supplement was detected on microbial N production. Plasma cholesterol concentration decreased linearity by increasing RDP concentration in diets (P0.05). In this regard, milk urea nitrogen, as well as triglyceride concentration in plasma, was not associated with dietary RDP concentration. To ensure a correct balance between energy and protein available in the rumen and consequently higher N efficiency for late lactation cows, a MUN content of 15.1mg/dl milk is the upper margin. Milk urea N is a simple and noninvasive measurement that can be used to monitor N efficiency in dairy cows.


Aims:  Antibiotic residues as well as antibiotic‐resistant bacteria in environmental samples might pose a risk to human health. This study aimed to investigate the association between antibiotic residues and bacterial antimicrobial resistance in liquid pig manure used as fertilizer.


Tsunami disaster caused great damages and very large victims especially when occurs in urban area along. Therefore information of evacuation in a map is very important for disaster preparedness in order to minimize the number of victims in affected area. Here, information generated from remote sensing satellite data (Landsat, SPOT-5 nad DEM) and secondary data (administration boundary and field survey data) are used ti simulate evacuation route and to produce a map for Padang City. Vulnerability and evacuation areas are determined based on information of maximum tsunami height in shoreline and topography condition. Landuse/landcover and infrastructure (road, bridge and building) are extracted from SPOT data. All the data obtained from remote sensing and secondary data are integrated using geospatial modeling to simulate tsunami evacuation routes. The simulation of evacuation route in Padang City for tsunami preparedness is provided by considering river line, shelters and save zone, available infrastructur (road), the shortest distance (to shelters and save zone) and local community experiences.


of all isolates obtained. About 30% of cultures were sensitive to lincomycin and the third generation cephalosporins - ceftriaxone, cefixime and cefoperazone. Conclusions. 1. Microflora isolated from synovial fluid in case of the knee and hip joints is inflammatory diseases is represented by gram-positive cocci (86.8%) in most cases, gram-negative rods amount is 7.3% and fungi of Candida and Cryptococcus genera are made 5.9%. 2. The isolated microorganisms species antimicrobials sensitivity is characterized by individual diversity with a tendency to vancomycin resistance increasing in 44.4% of coagulase-positive staphylococcus isolates, of which 28.6% are S. aureus strains; 28.5% o are other staphylococcus species cultures and 16.7% are S. pyogenes isolates. This indicates the exactly appropriate antibiotic therapy conducting necessity. 3. When choosing antibiotic therapy in patients in case of coxarthrosis and gonarthrosis it is recommended to take into account the bacterial isolates antibiotic resistance formation actual trends.


: Human mobility has been studied by researchers from many fields such as urban planning, transportation research, geography, computational epidemiology, etc. It has also been modeled using various data sources from different attributes. However, human mobility shows great spatial and temporal complexity, and many aspects remain unknown. In this study, we propose a method of reproducing one-day human mobility based on the time-varying Markov Chain model. A step of choosing individual's future status before the Markov process is conducted, which uses the information of previous mobility. Results show that the spatial and the temporal attributes are well-reproduced, and individual future status can be inferred from the type of previously mobility, regardless of where exactly the person has traveled and when trips happened. Our method can be a tool to infer spatial and temporal attributes of individual mobility from knowledge about aggregated mobility.


A grating lateral shear interferometer is described that can be used with a white light source. The use of the interferometer with certain types of extended sources is also demonstrated.


$^{\dagger}$ Supported by the petroleum Research Fund of the American Chemical Society, National Science Foundation and Rutgers University Research Council.


Part 1 Introduction to the bolted joint: basic concepts stress and strength considerations threads and their strength materials stiffness and strain considerations. Part 2 Tightening the joint (establishing the clamping force): introduction to assembly torque control of bolt preload torque and turn control stretch control preload control ultrasonic measurement of bolt stretch or tension. Part 3 The joint in service: theoretical behaviour of the joint under tensile loads behaviour of the joint loaded in tension - a closer look in-service behaviour of a shear joint joint failure self loosening fatigue failure corrosion gasketed joints and leaks. Part 4 Using the information: selecting preload for an existing joint design of joints loaded in tension the design of gasketed joints the design of joints loaded in shear.


In a former communication to the Royal Society of Edinburgh, I gave an account of an unusual fall of rain in the Lake District in the month of January last year. That occurrence was followed by its opposite in May, June, and July; not for a long period, not since 1826, has the district suffered more from want of water than in those months. This drought is best shown by the following table, in which will be found the rain-fall for the several months of the year at five different places, only a few miles remote from each other. The table will also show the remarkable contrast as to excess and deficiency of rain during the period. It may be premised, that at Ambleside, where the drought appears to have been felt as much as anywhere, the ordinary fall of rain for the months in question is about three times as great; thus for May (our driest month of the twelve), taking the average of the preceding eleven years, it is 2·37 inches, for June 4·22 inches, for July 5·27 inches, making a total of 12·36 inches, against 4·54 inches of the months of drought.


The present invention relates to a device for the wheel / axis adjustment in a motor vehicle, having a lifting platform on which the motor vehicle to be fixed and on which it can be raised, wherein Radmontageabschnitte are arranged exposed. , The invention is characterized in that the device comprises at least the following components, measuring arms for measuring a vehicle height measuring wheels for measuring the camber or track for later to assemble vehicle wheels, support columns, on which the motor vehicle with the measuring wheel can be set down, load cells for determining the weight distribution the individual frame members. This can achieve a highly accurate, yet simple adjustment of a chassis of a motor vehicle, which are not mounted in the adjustment state the vehicle wheels.


Objective:To evaluate the effect of pit and fissure sealant on caries prevention in our country.Methods:We searched cochrane CBM,CNKI and WANFANG datebase for randomized controlled trials(RCTs)about pit and fissure sealant on caries prevention published in 2004~2014.The quality of RCTs was critically appraised and extracted,and performed meta-analyses by using the RevMan 5.2software.Results:21studies met the inclusion criteria.The results of meta-analyses showed that:After one year of pit and fissure sealing the teeth which had accepted pit and fissure sealant had lower caries prevalence rate,the RR and 95% CI were 0.12,0.07-0.19.After two years of pit and fissure sealing the teeth which had accepted pit and fissure sealant sealing had lower caries prevalence rate,the RR and 95% CI were 0.19,0.12-0.30.After three years of pit and fissure sealing the teeth which had accepted pit and fissure sealing had lower caries prevalence rate,the RR and 95% CI were 0.21,0.16-0.28.Conclusions:The current evidence indicated in the short run pit and fissure sealant can reduce the rate of dental caries occurrence.


Due to the increasing demand of an extra-low-power system, a great amount of research effort has been spent in the past to develop an effective and economic subthreshold-SRAM design. However, the test methods regarding those newly developed subthreshold-SRAM designs have not yet been fully discussed. In this paper, we first categorize the subthreshold-SRAM designs into three types, study the faulty behavior of different open defects for each type of designs, and then identify the faults which may or may not be covered by a traditional SRAM test method. For those hard-to-detect faults, we will further discuss the corresponding test method according to different each type of subthreshold-SRAM designs. At last, a discussion about the temperature at test will also be provided.


Science has recently handed us an "inconveniently simple" concept to think about climate change: to keep global temperatures from rising to dangerous levels, we may only burn a very limited amount of fossil fuels in the next hundred years. This carbon budget has to be shared fairly among nations. Applying the novel approach of negotiation engineering, we propose a simple mathematical model for the climate change negotiations: to agree on a cutting of the carbon cake, parties select fairness principles and decide to which degree they should be applied. We call this "negotiation on principles".We investigate some properties of the model and as an application assess the fairness of past and present allocations of the budget.


Methods Between June 2011 and July 2013, 304 patients were consecutively referred to our institution after an acute event (cardiac surgery, acute coronary syndrome or acute heart failure). Our CR program consists of 4 sessions per week for 5 weeks (total of 20 sessions) and includes both exercise and health and nutrition education sessions. Glomerular filtration rate (GFR) was calculated based on the Modification of diet in renal disease (MDRD) formula and CKD was defined as estimated GFR <60ml/min/1.73m. Patients were divided into two groups according to their renal function.


The present invention relates to a drive pin assembly. Further it is provided a system, apparatus and method relates to a transmission pin member assembly. Such an assembly comprising: a first pin member and a second pin member, each engagement portion having an end opening toward the interior space and having a portion extending for such a width of at least a first pin member and a portion of the length of the angularly a surface; and a fastening means, at least partially disposed within the interior space of the first pin member and the second pin member, a first pin member and the second pin member closer close together, wherein the first angled surface of the pin member has a surface matching the angle of the second pin member so that the first pin member and a second pin member are close together vertically and laterally slide in both directions along each other.


The purpose of this study was to investigate the relationship between Health status and Quality of Life. The data were collected from 124 living alone elderly in Seoul from October, 2000 to June. 2001. Health status were measured by ADL, nutritional status and quality of life were measured by cognitive function and depression.
 The data were analyzed using the SPSS program by frequency, percentiles, t-test, ANOVA, Scheffe´ test, Pearson correlation coefficient and Stepwise multiple regression.
 The results were as follows :
 1. The mean score for ADL was 24.12: for nutritional status was 7.70; for MMSE-K was 26.25: for depression was 7.30.
 2. The score of ADL was positively correlated with the score of nutritional status and MMSE-K and negatively correlated with depression. Also nutritional status were negatively correlated with depression.
 3. The factors influencing depression were ADL, the number of children, and disease. The three factors explained 23.2% of the variance of depression.
 4. ADL was significantly different by age, educational level, monthly income, and residential type', nutritional status by age, marital status, monthly income', MMSE-K by age, marital status, educational level, monthly income, residental type: depression by the number of children, monthly income, and disease.


The second Vladikavkaz City School was opened as an additional one to the Nikolaev City School. For a long time, both schools were in close relationship. The main stages of the study can be divided into three points: 1. The question of the organization of the school – that is, to what extent there was a need to open one. 2. The moment of the very opening and further functioning – the initial program, changes in the program in different years, expansion of staff and subjects of teaching. 3. Reformation or in other words, the transformation of the school, which contributed to the improvement of its status as an educational institution. The article reflects the main activities of this educational institution, its program, difficulties and, on the contrary, its successes and achievements as a city educational institution in different years. Most of the publication is devoted specifically to the process of opening a school, since this issue was solved in rather difficult material conditions of the city council, the directorate of public schools, the inspection of the same schools – which are dependent on each other. In a number of places of work, verbatim correspondence of government representatives is provided, so that researchers and readers can have the most objective idea about the opening of the school and its history as a whole. In the course of the research, the regulations, rules and resolutions of the Ministry of Public Education, the Directorate of Public Schools and the Ministry of Internal Affairs were used as sources, since in the pre-revolutionary period it controlled not only the legal aspects of society but also the social sphere. The second city school gave the city of Vladikavkaz and the region as a whole several generations of literate people and in the future – specialists in various industries, since many of its graduates were able to continue their education in secondary and higher educational institutions.


Dealing with the Korean language this pack, containing two audio cassettes and text, provides an introduction to communicating confidently and effectively in everyday situations. It moves from the basics to a developed understanding of the spoken and written language.


Purpose
Strategizing in a multinational corporation requires balancing global and local strategy. The purpose of this paper is to provide some insights into how multinational corporations succeed in this endeavor.

Design/methodology/approach
The authors conducted a detailed qualitative investigation of the strategy-development processes at Gamma – a European multinational corporation in the materials industry. Specifically, the authors investigated strategy development in the DACH region (i.e., for the German, Austrian and Swiss subsidiaries). To collect data, they conducted interviews with key informants at the corporate headquarters and the subsidiaries and collected archival data.

Findings
The data revealed that Gamma had found an approach to strategy development that balanced its global strategy with local conditions, finding a suitable way to align its global and local strategies. The authors therefore unravel three key insights revolving around subsidiaries' unique interpretations of the basic idea of global strategy, idiosyncratic strategy development processes in subsidiaries and globally and locally synchronized temporal structures.

Originality/value
Knowing how to balance the strategic needs of headquarters and subsidiaries allows multinational corporations to follow a general strategy while simultaneously developing a local market strategy responsive to the individual market requirements.


(51) Int. Cl. CI2P I 7/16 (2006.01) (52) U.S. Cl. ........................................................ 435/118 (57) ABSTRACT A process for the purification and recovery of Tacrolimus (I) (17-allyl-1,14-dihydroxy-12-2-(4-hydroxy-3-methoxycy clohexyl)-1-methyvinyl-23,25-dimethoxy-13, 19.21.27-tet ramethyl-11.28-dioxi-4-azatricyclo-126.96.36.199"octacos-18 en-2.3.10, 16-tetraone), starting from Streptomyces sp fermentation broth. The process is particularly advantageous in terms of productivity and selectivity of the separation of impurities.


The metabolic response of the RIF‐1 tumor to 5‐fluorouracil (a single dose of 260 mg 5FU/kg, ip) was monitored in 10 mice using 19F and 31P MR spectroscopy. 19F MRS revealed a continuous drop in tumor 5FU level and an increase in the fluoronucleotide (Fnuc) signal to a plateau value of 50% of the initial 5FU level, during the first 2 h after chemotherapy. Although the 31P MR spectra of the tumors showed no significant initial changes, the total level of MR visible tumor phosphate decreased and tumor pH increased during the subsequent days. The changes in phosphate metabolism and tumor pH did not correlate with the detected fluorine levels or tumor response. However, the pretreatment Pi level, the plateau Fnuc level, and the 5FU induced decrease in tumor volume showed significant correlation. The indicates that both 19F and 31P MR spectroscopy have potential for predicting reponse to 5FU chemotherapy. © 1991 Academic Press, Inc.


Submitted for the DFD11 Meeting of The American Physical Society High-order jet-schemes for problems with moving interfaces JEAN-CHRISTOPHE NAVE, McGill University, BENJAMIN SEIBOLD, Temple University, RUBEN ROSALES, MIT — Gradient-augmented and more generally jet-schemes belong to a new class of optimally-local and high order methods. In this talk I will present their general formalism and show several applications to level set interface tracking problems. Also, I will try to highlight the ubiquity of the approach and the simplicity of implementation. Jean-Christophe Nave McGill University Date submitted: 04 Aug 2011 Electronic form version 1.4


Make more knowledge even in less time every day. You may not always spend your time and money to go abroad and get the experience and knowledge by yourself. Reading is a good alternative to do in getting this desirable knowledge and experience. You may gain many things from experiencing directly, but of course it will spend much money. So here, by reading harbin russian imprints bibliography as history 1898 1961 materials for a definitive bibliography, you can take more advantages with limited budget.


Conceptual mechanism mounted in handle of spray gun maintains constant ratio between volumetric flow rates in two channels leading to spray head. With mechanism, possible to keep flow ratio near 1:1 (or another desired ratio) over range of temperatures, orifice or channel sizes, or clogging conditions.


This paper concerns the development of a hierarchical framework for the planning and scheduling of a class of manufacturing systems. In this framework, dynamic optimization plays an important role in order to define control strategies that, by taking into account the dynamic nature of these systems, minimize customized cost functionals subject to state and control constraints. The proposed architecture is composed of two hierarchical levels where a two way information flow, assuming the form of a state feedback control, is obtained through a receding horizon control scheme. At the higher level, an optimal control problem is solved by an iterative algorithm in order to define the control strategies in terms of aggregated production rates for the various subsystems. At the lower level, this control strategy is further refined in such a way that all sequences of operations are fully specified. Although this stage is strongly problem dependent an approach based on the notion of critical machine plays an important role in order to exploit the available flexibility.<<ETX>>


Mitochondrial DNA has a simple structure, it is maternally inherited, with no recombination, and it replicates independently from the nuclear genome. In addition, it has different rate of evolution, usually much faster than that of its nuclear counterpart, facilitating our ability to infer phylogenetic relationships among closely related organisms. The complete mitochondrial genomic sequences belonging to 71 species of order diptera of Class Insecta have been retrieved from the GenBank and Vector base to prepare a database. The base compositional analysis of complete genome, protein coding genes as well as AT rich region suggests that mitochondrial genome is heavily AT biased which may targets mitochondrial genome towards lesser stability and more prone towards directional mutation pressure. Thus, indicating that the higher AT content shows that mitochondrial genome has higher rate of evolution. However, coding content conservation, maternal inheritance, high mutation rate makes the mitochondrial DNA the molecule of choice of evolutionary studies.


A commercial density/sorption system has been converted to a dual-sinker densimeter and used to make density measurements for some light hydrocarbon mixtures in the compressed gas region and near dew-point conditions. Argon was used as a reference fluid for calibration of the measurement system. Experimental uncertainties in density for methane were estimated as ±(0.029% + 0.013 kg m-3), including claimed uncertainties in the argon reference data. Measured methane densities at temperatures of (273 to 313) K and pressures to 12 MPa agreed within combined uncertainties with a methane equation of state in the literature (claimed uncertainty of 0.03%). Densities are reported along isotherms in this same range for selected methane + propane and methane + propane + hexane mixtures with cricondentherms below 293 K. Estimated experimental uncertainties for these mixtures are slightly larger than those for pure methane, because of uncertainties in compositions. Additional isochoric experiments were performed on so...


The polymerization of methyl methacrylate by alkali metal alkoxides was carried out in aprotic dipolar solvents such as hexamethylphosphoramide, dimethylsulfoxide, and dimethylacetamide. The polymerization was drastically promoted by these solvents, even by the presence of small quantities of them. Tetramethylethylenediamine and ethereal solvents also promoted the reaction, although these solvents were less effective than the aprotic dipolar type. Such an effect of the solvent was explained in terms of the donor property and the dielectric constant of the solvent. Alkali metal salts of 2-substituted ethanols such as 2-methoxyethanol and 2-dimethyl-aminoethanol were effective as the initiator. The structure of the polymer was discussed with regard to the property of the propagating active end.


The rate constant for vibrational-vibrational exchange, K1001 = (1 ± 0.4) × 10−13 cm3/sec, was determined under conditions of selective biharmonic excitation of the first vibrational state of nitrogen. Procedural aspects of measurements of the vibrational relaxation time under biharmonic excitation conditions are discussed.


Introduction Preliminaries Since Ronald Dworkin wrote Hard Cases,' coherence has been a pivotal-perhaps the pivotal-explanatory and justificatory concept in theories of law and adjudication.2 Crudely put, Dworkin's view is that a purported proposition of law is valid if it follows from the most coherent set of principles that explains and justifies the settled, black-letter law.3 Although coherentist methods permeate modern theories of law4 and justice,5 and although coherence is the crucial explanatory and justificatory concept in many theories, including Dworkin's6 and Weinrib's,? theorists of law and justice have been curiously vague about what coherence is, and about when a legal system, a legal theory, or a set of norms is coherent. The regrettable result is that claims regarding coherence-especially regarding its normative virtues-cannot be adequately assessed: our understanding of coherence is too meager for us even to know where to begin. In a larger project of which this Article constitutes a part,8 I intend to remedy this unfortunate state of affairs by developing an analytic framework within which to categorize differing conceptions of coherence. I then plan to demonstrate the framework's explanatory power by analyzing claims about coherence made by John Rawls, Lon Fuller, Ernest Weinrib, and Ronald Dworkin. In this Article, I restrict myself to Dworkin. I do so because he has developed the most prominent and influential coherence theory of law and adjudication. My overall aim is to canvass some normative virtues and vices of his theory, which he initially labeled "the rights thesis"9 and now denominates "law as integrity."'o While noting one serious normative flaw in Dworkin's coherentist theory-it sometimes applies law retroactively, even when correctly followed-I argue that law gradually will improve morally over time if Dworkin's theory is correctly employed by judges. Moreover, contrary to the views of Dworkin and his critics, I argue that his view is less conservative than the conventional wisdom asserts. According to that wisdom, the best theory of the settled lawwhich is, for Dworkin, the law-must fit the overwhelming bulk of the settled law." For this reason, it is claimed that Dworkinian methodology projects the ideology embedded in the settled law into the future, and is thus inherently conservative."2 To the contrary, I urge that the requirement of fit with the settled law in Dworkinian coherentist theory is much lower than is commonly assumed. This allows the moral aspects of Dworkin's theory to dominate the ideology implicit in the settled law. Coherence theories-qua coherence theories-may not only evolve toward critical morality; they are also potentially subject to radical transformations toward justice. Dworkin's theory has the flexibility-under certain circumstances, described in Part IV-to be morally superior in terms of outcomes to what both Dworkin and his critics have previously thought. Still, there are other extant jurisprudential theories. Depending upon the circumstances, judges who follow either Hartian positivism (or some form of strict construction) or natural law theory will produce morally better outcomes overall than those who follow Dworkin's mixed methodology which partakes of both positivist description and natural law normativity. Under no circumstances is Dworkinian coherentism the preferable methodology evaluated in terms of producing the morally best outcomes. The measure of morally best outcomes will consider the percentage of morally correct outcomes, the distribution of morally incorrect decisions in terms of their "closeness to" or distance from morally correct decisions, the distribution of decisions as a function of their importance in protecting significant rights and interests, the number of interactions that each decision will regulate, and the like. Although I do not maintain that the moral correctness of outcomes is the only criterion for assessing jurisprudential methodologies and legal theories, nevertheless, I do believe that it is the most important criterion. …


Pursuant to adjournment at the last meeting, the Executive Council of the American Society of International Law met in the Willard Room of the Willard Hotel in Washington, D. C, on Saturday, April 29, 1933, at 11.30 o'clock a. m. The meeting was called to order by the President, Dr. James Brown Scott. The Secretary, Mr. George A. Finch, called the roll and the following members were present: Hollis R. Bailey Herbert W. Briggs Philip Marshall Brown Charles Henry Butler Kenneth W. Colegrove Edwin D. Dickinson George A. Finch James W. Garner Manley 0. Hudson William I. Hull Howard T. Kingsbury Charles E. Martin Frederic D. McKenney Denys P. Myers Fred K. Nielsen William J. Price Harold S. Quigley Jackson H. Ralston Bessie C. Randolph Jesse S. Reeves James Brown Scott Irvin Stewart Elbert D. Thomas George T. Weitzel George Grafton Wilson Lester H. Woolsey Herbert Wright


In this work we consider modeling of services with workow modules, which are a subclass of Petri nets. The service compatibility problem is to answer the question, whether two Web services t together, i.e. whether the composed system is sound. We study complementarity of service produced/consumed resources, that is a necessary condition for the service compatibility. Resources, which are produced/consumed by a Web service, are described as a multiset language. We dene an algebra of multiset languages and present an algorithm for checking the conformance of resources for two given structured workow modules.


Abstract The monoblock divertor target plate (MDTP) is a mainstream divertor target plate. MDTP was installed in EAST and in WEST and will be used in ITER. Local high-temperature hot spots (HS) were observed on MDTP during a plasma experiment. HS will reduce the lifetime of MDTP. In this paper, the causes of HS on MDTP are determined through theoretical analysis and are verified by numerical simulations. The HS on MDTP seem to be caused by small high-density heat load areas on the toroidal and poloidal direction surfaces facing the incident direction of the plasma strike line (PSL) of the MDTP tungsten block. When toroidal HS and poloidal HS appear simultaneously, a super local high-temperature HS will be formed at the corner (facing the incident direction of PSL) of the MDTP tungsten block. The HS on MDTP can be eliminated by optimizing the geometry of the MDTP tungsten block, when the plasma configuration is determined. A method and the scope of application of the method, which can be used for tungsten block geometry optimization, are given in this paper. In order to facilitate the selection of a divertor configuration, the heat flux–carrying performance of the optimized MDTP was evaluated. In order to attain a maximum temperature within MDTP of less than 900 K, it was found that if the poloidal incidence angle between PSL and MDTP can be stably controlled as 5 deg (or 35 deg), MDTP can directly withstand PSL with a peak heat flux density of no more than 90 (or 40 ).


The aim of this work is to address the problem of preserving privacy whendata is released. More specifically, we will focus on the concept ofDifferen-tial Privacywhich provides a new quantitative approach to confidentialityprotection, set in a rigorous mathematical framework.


Furthermore haejugo to be an object of the present invention is to memorize English words effectively is for you, as well as a way to ease the writing practice of foreign languages offered to play combine learning card that can be used to play cards for families, for this purpose play combine learning cards to achieve is a letter or a word in the first language, the first card, the second language in the word or phrase is displayed in the display, each separated from each other and are displayed on the first card, arranged in a predetermined order the multiple second card and consists of a configuration, memorization of foreign words, relatively simple writing exercises, relatively difficult writing practice includes representing a word or sentence meaning of one language in a word or sentence in the second language step by step to do it in elementary school, junior high, high school and college students, as well as the public in foreign languages It provides the effect of being able to facilitate learning.


To secure cloud computing and outsourced data while meeting the re9 quirements of automation, many intrusion detection schemes based on deep learn10 ing are proposed. Though the detection rate of many network intrusion detection 11 solutions can be quite high nowadays, their identification accuracy on imbalanced 12 abnormal network traffic still remains low. Therefore, this paper proposes a ResNet 13 &Inception-based convolutional neural network (RICNN) model to abnormal traf14 fic classification. RICNN can learn more traffic features through the Inception unit, 15 and the degradation problem of the network is eliminated through the direct map16 ping unit of ResNet, thus the improvement of the model's generalization ability can 17 be achievable. In addition, to simplify the network, an improved version of RICNN, 18 which makes it possible to reduce the number of parameters that need to be learnt 19 without degrading identification accuracy, is also proposed in this paper. The ex20 perimental results on the dataset CICIDS2017 show that RICNN not only achieves 21 an overall accuracy of 99.386% but also has a high detection rate across different 22 categories, especially for small samples. The comparison experiments show that the 23 recognition rate of RICNN outperforms a variety of CNN models and RNN models, 24 and the best detection accuracy can be achieved. 25


Quinoa (Chenopodium quinoa Willd.) is a native plant from the Andean region of South America whose nutritional value can exceed those of traditional cereals. Several studies have shown that quinoa is sensitive to photoperiod during its development. However, no accurate records exist for accessions from different production areas along a latitudinal distribution of Chilean quinoa regarding the photoperiod effect on the duration of its vegetative phase. The duration of the vegetative phase is a key component of the adaptation of annual crops to different environments. In the case of quinoa, one of the reasons for proposing its cultivation as an alternative to the current existing crops, besides its nutritional value and tolerance to adversity, is its earliness. The aim of this study was to evaluate the effect of two photoperiods applied from quinoa planting on the duration of the vegetative phase. For this purpose, work was conducted with three accessions: "Yellow" from the Chilean Altiplano, "Peach" from the Region of Coquimbo and "Baer" from Southern Chile. Plants were grown under 15 and 9 hours of light. The temperature was maintained at 20± 2oC throughout the test. In comparing the responses obtained in the short and long photoperiods, it was found that in the latter all accessions increased the duration of their vegetative phase, this increase being 33 days in the "Yellow" accession, 25 days in "Baer" and 23 days in "Peach". Consequently, the long-day photoperiod delayed the time of floral initiation in all three quinoa accessions, resulting in an increased number of floral initiation nodes ( 13 nodes in "Yellow", 5 in "Peach" and 7 in "Baer"). It was found that photoperiod sensitivity (PPS, oCdh-1) varied between 64,8 and 92,8 in the accessions evaluated.


Abstract Following a fire in a sphagnum-wirerush mossland (Sphagnum cristatum-Empodisma minus) in Te Anau Basin, permanent transects were established and recovery of the wetland monitored annually using visual estimation of plant cover. Within four and a half years of the fire, total plant cover had reached 90% or more throughout the wetland, having been reduced by the fire to as low as 7%. Wetter parts of the wetland were less severely burnt and recovered more quickly than drier parts. In the latter, herbs and grasses, including naturalised species, were important early colonists but mostly non-persistent. Rhizomatous species were important components of the cover throughout the wetland. While the wetland had apparently almost recovered in terms of vegetation cover and species diversity by four and a half years, the vegetation composition differed from that prior to the fire, principally in terms of species dominance, and to some extent, species presence. It is suggested that, over time, the vegetation c...


Optical wavelength division multiplexers (WDM) were tested for performance degradation as a result of temperature cycling, shock and pulling on the fiber leads to determine tensile strength. The WDM components tested use multidielectric coatings to separate two channels, one ranging from 0.75 to 0.95 micron and the other from 1.2 to 1.6 microns. The optical crosstalk remained constant under the various tests and the insertion loss variation was small.


Social rehabilitation of the disabled is one of the most important issues for the modern society. On the example of the specialized boarding school the scientific experiment that evaluates the effectiveness of the influence of chess classes for the children with sight disabilities was held among the visually impaired children. The novelty of the methods of teaching was in use of the different playing techniques and implementation of information technologies in the educational process. The author conducted a series of tests aimed at determining the level of the social adaptation of pupils of primary and middle classes, both groups involved and not involved in chess. The obtained results allow making a conclusion about the effectiveness of playing chess according to this method, both from the point of view of achieving the sports results, and from the point of view of increasing the level of socialization of the pupils.


Aiming at the deficiency of traditional dam deformation monitoring,a stepwise regression model with artificial bee colony algorithm(ABCA)is proposed for dam deformation monitoring in this paper.Firstly,the predictor variables are selected by stepwise regression,and the main statistical methods used include:correlation analysis,multiple co-linear relation and so on.Then the coefficients of the regression model are reevaluated by an improved artificial bee colony algorithm.ABCA is a novel swarm intelligence optimization algorithm,and it is introduced into dam health monitoring in this paper.Meanwhile,to improve the performance of local search of ABCA,the simplex operators are introduced into the basic ABCA.Examples show that the proposed model for dam deformation monitoring is more effective compared to similar models,considering it can simply the prediction model and improve the accuracy of fitting and prediction.


To get beyond simplistic measures such as increased patient appointments or decreased lag days, operations administrators and physician champions must develop effective partnerships.


1 Department of Chemical Engineering and Materials Science, University of California, Davis, CA 95616, USA 2 Department of Materials Science and Engineering, North Carolina State University, Raleigh, NC 27695-7907, USA 3 Department of Materials Science and Engineering, University of North Texas, Denton, TX 76203, USA 4 Department of Metals and Materials Engineering, University of British Columbia, Vancouver, BC, Canada V6T 1Z4


A chicken lymphoblastoid cell line (TLT)‐6855 originally established from an avian oncornavirus‐induced lymphoma (Siegfried and Olson, 1972) was studied for the presence and expression of Marek's disease virus (MDV) genome. By nucleic acid hybridization a significant amount of MDV DNA was found in this cell line. This virus DNA, however, was not expressed in either virus‐specific intracellular or membrane antigens or the MD‐associated tumour‐specific surface antigen (MATSA). Moreover, MDV‐specific antigens could not be activated in this cell line by treatment with 5‐IdUrd. In several experiments, when chickens were inoculated with the cell line a herpesvirus was repeatedly isolated from the kidneys. This herpesvirus was antigenically similar to MDV but was low in oncogenicity for chickens.


Micro-insurance has a protective role against risk in low-income households. The present study designed a micro-insurance development model for rural areas. The data was collected from 60 questionnaires given to experts of the Agricultural Insurance Fund and the Insurance Institute. The findings from the structural equation model developed using PLS show that the order of latent variables affecting on micro-insurance development were socio-cultural (B = 0.518), economic (B = 0.269) and educational (B = 0.265). The results showed that this model is appropriate for development of micro-insurance in rural areas for low-income households.


Firstly, overall planning of east line of the south-to-north water diversion project, main construction items and reasons for setting up dispatching management system of first-phase in east line are briefly introduced. The article mainly describes construction principles, construction objects, construction contents and system functions of dispatching management system for first-phase in east line of south-to-north water diversion project. The dispatching and management system set up by applying modern advanced technologies such as sensing, communication, network, computer control processing and database analysis will bring into full play the economic and social benefits of south-to-north water diversion project.


Groundwater provides more than 40 percent of California's drinking water. To protect this vital resource, the State of California created the Groundwater Ambient Monitoring and Assessment (GAMA) Program. The Priority Basin Project (PBP) of the GAMA Program provides a comprehensive assessment of the State's groundwater quality and increases public access to groundwater-quality information. The Sierra Nevada Regional study unit constitutes one of the study units being evaluated.


Acute kidney injury (AKI) is a well-recognized complication of critical illness with a large effect on mortality. Although the indications of renal replacement therapy (RRT) in patients with life-threatening complications are unequivocal, the timing of RRT initiation in patients with severe AKI without such complications has not yet been defined. Two recently large randomized controlled trials (RCT) may provide new evidence of initiation of RRT. The aim of this paper is to analyze the main differences, strengths and limitations of ELAIN and AKIKI study and to finally point out the timing of RRT initiation.

Key words:
Acute kidney injury; Renal replacement therapy; Therapy timing


Radiographic images are commonly used to detect aseptic loosening of the hip implant in patients with total hip replacement (THR) surgeries. These techniques of manual assessment by medical professionals can suffer from the drawback of low accuracy, poor inter-observer reliability, delays due to the unavailability of experienced clinicians. Thus, the paper provides a reliable Deep Convolutional Neural Networks (DCNNs) based novel stacking approach (HipXNet) for detecting loosening of the hip implant using X-ray images. Two major investigations were done in this study. Firstly, the performance of four different state-of-the-art object detection YOLOv5 models was evaluated to detect the implant region from the hip X-ray images. Secondly, the study developed a stacking classifier using three different Convolutional neural networks (CNN) models to classify aseptic hip loosening and compared the performance with eight different state-of-the-art CNN networks. Moreover, one publicly accessible dataset with two sub-sets was created for these two experiments, where 200 hip implant X-ray images were collected and annotated by two expert radiologists for implant detection and 206 hip implant X-ray images were collected for loosening detection. YOLOv5m model outperformed the other variants of YOLOv5 to detect the implant region with the precision, recall, mean average precision (mAP)0.5, mAP0.5-0.95 of 100%, 100%, 100%, and 87.8%, respectively. Densenet201 CNN model outperformed other CNN models with the accuracy, precision, sensitivity, F1 score, and specificity of 94.66%, 94.66%, 94.66%, 94.66%, and 94.5%, respectively while the stacking technique with Random Forest meta learner classifier produced the best performance with the accuracy, precision, sensitivity, F1 score and specificity of 96.11%, 96.42%, 96.42%, 96.42%, and 96.74% respectively for loosening detection. The reliability of the performance was confirmed by the popular Score-CAM visualization. This study can help in the early and fast identification of hip implant loosening with the help of simple X-ray images and computed aided diagnosis.


Disclosed is a sputtering target that can form a Cu oxide layer evenly on a substrate. The sputtering target comprises Cu, oxygen, and unavoidable impurities.  The content of oxygen is 7.0 to 33.3 atom% when the total content of Cu and oxygen is presumed to be 100 atomic%.  Also disclosed is a process for producing a sputtering target that obtains a Cu sintered compact as a sputtering target material by heat treating a Cu powder in an oxygen-containing atmosphere to introduce oxygen, then performing pressure sintering to brining an oxygen content of 7.0 to 33.3 atom% when the total content of Cu and oxygen is presumed to be 100 atomic%.


Background: Obesity in pregnant women has been linked to negative outcomes for both the mother and the fetus. Gestational diabetes, preeclampsia, and postpartum haemorrhage are all threats for mothers during pregnancy. These may also affect labor outcomes because fat accumulation in the pelvis makes obese pregnant women more likely to have a caesarean section. Objective: To analyze the outcome of maternal obesity in pregnancy in 2017. Materials and Methods: This was an analytic cross-sectional, observational study in pregnant women with obesity in Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, within the period of January 1st – December 31st 2017 using medical records. Sample size was determined using cross-sectional sample size calculation with the result of n=162. After receiving approval of ethical clearance, medical records were collected and analyzed. The statistical analysis was done using chi-square test. Results: From a total of 162 subjects, most of the patients were 21-34 y/o (56.8%), under graduate (90.7%) and 58% of the subjects worked. Proportion of grade I, II and III were 60.5%, 22.2%, and 17.3%, and 67% suffered from complications such as PE, DM, PE with DM with percentages as follows: 56.2%, 4.9%, and 6.2%. Neonatal complications were preterm 42.6%, macrosomia 4.3%, stillbirth 4.9%, and low Apgar score 48.1%. No association was identified between maternal age and complications in grade I (p=0.764) and grade III (p=0.716). Obesity grades I and III had correlation with complications (p=0.035). Conclusion: No significant association was found between age and complications in grade III obesity, while there was significant correlation between obesity levels (grade I and grade III) and complications.


I discovered this book, not through a dance periodical or the recommendation of a scholarly friend, but by chance upon the shelves of a museum shop. Perhaps this was an apt way to approach Dancing in the Streets, for although the book's title includes the word "dance" it is not a dance book in any traditional sense. The author, Barbara Ehrenreich, is neither a dancer nor a dance scholar, but rather a prolific writer whose work has appeared in Time magazine, the New York Times, and Harper's as well as made the New York Times bestseller list. She is a journalist and social critic and her previous books, spanning a wide range of topics, include the well-known Blood Rites, which addressed issues of warfare throughout history. In Dancing in the Streets, Ehrenreich delves into the question of why groups of people come together to celebrate. She terms her subject of inquiry—a phenomenon that encompasses both dance and other aspects of festive ritual—"collective joy" or "collective ecstasy." Collective joy includes dancing, feasting, wearing costumes, inverting the usual social order, and entering ecstatic or trance states. One of Ehrenreich's premises is that the collective joy created by dance has been a vital part of human life throughout history: "The question that motivates this book originates in a sense of loss: If ecstatic rituals and festivities were once so widespread, why is so little left of them today? If the 'techniques' of ecstasy represent an important part of the human cultural heritage, why have we forgotten them, if indeed we have?" (p. 19). As Ehrenreich addresses


In order to promote the development of the Syzygium samarangense processing industry,Syzygium samarangense wine fermentation process was researched.By examining a number of factors affect the fermentation effect,the best fermentation process was determined: yeast inoculum concentration of 0.6 g/L,initial pH 3.5,fermentation temperature 21~25 ℃ and fermentation time of 14 days.Trial Syzygium samarangense wine was yellow,clear and transparent.In addition,it showed a certain amount of Syzygium samarangense fruity bouquet,refreshing and unique style.


Daily activities can become more challenging for people as they age or if they have a medical condition that inhibits their manipulation or mobility capabilities. Such individuals often engage in rehabilitation to improve or restore their abilities. Yet their diminished strength, endurance, or ability can limit the intensity and number of repetitions (the rehabilitation dosage) needed to achieve the desired training effects. As a result, therapeutic adjuvants, such as functional electrical stimulation (FES) and/or rehabilitation robotics, are often used by therapists to facilitate musculoskeletal and cardiorespiratory fitness as well as other neurological, physiological, and psychological measures.


We have observed two patients who exhibited an exclusive increase of δ TCS1+ subset of αδ T cells in the peripheral blood after bone marrow transplantation (BMT). In one case with severe combined immunodeficiency (SCID) who received haploidentical BMT from his father, αδ T cells appeared only after thymus transplantation. However, his T cell‐mediated immunity remained severely defective despite the generation of T cells of donor origin. In the other case with aplastic anemia, δ T CS1‐αδ T cells began to increase in the peripheral blood later. This indicates that the thymus is necessary for the generation of αδ T cells and that the δ TCS1+ subset is dominant in the early stages of their ontogeny. δ TCS1+ T cell lines were established from both patients, and allo‐reactivity was investigated. The cell line from the latter case reacted to recipient cells in a mixed lymphocyte reaction, but did not show cytotoxity to the allogeneic cells including recipient cells. The other cell line, from the former case, did not react to either donor or recipient cells. This indicates that an intact thymus is needed for αδ T cells to acquire allo‐reactivity. Both cell lines showed MHC non‐restricted cytotoxity against NK‐sensitive target cells.