Diffuse intrinsic pontine gliomas (DIPG's) are immunologically inert tumors with a median survival of 9–15 months. Radiation therapy (RT) is the mainstay treatment for DIPG but is associated with immunodepletion of the tumor microenvironment (TME) at high dose ranges. FLASH, or ultra-fast dose rate RT, represents a novel ablative technique that may spare TME immune responses while decreasing tumor burden. Here, we present single-cell immune profiling of DIPG tumors treated with FLASH, conventional dose rate RT (CONV) or no RT (SHAM).Murine H3.3K27M mutant DIPG cells were stereotactically injected and tumor induction confirmed by magnetic resonance imaging (MRI) 15 days later. DIPG-bearing mice were randomly assigned to one of three treatment groups (n=4/group), FLASH, CONV or SHAM. A fourth group with no tumor (NML) was included as a negative biological control. A modified linear accelerator was used to deliver 15 Gy of electron RT to the brainstem at dose rates of 90 Gy/second and 2 Gy/minute, for the FLASH and CONV groups, respectively. Four days post-RT, mice brainstems were harvested, homogenized, stained for CD45 and tagged with a hashtag antibody specific to each group. CD45+ immune cells were isolated and sequenced using the 10X Genomics chromium single-cell 3' platform. After processing and alignment of the reads using CellRanger with default parameters, the data was quality checked and filtered before hashtag demultiplexing, unsupervised clustering and downstream analysis was implemented following the Seurat R package. Differential expression evaluated based on the non-parametric Wilcoxon rank sum test. Key genes determine by an adjusted p value of < 0.05 based on bonferroni correction and |avg log2FC| > 0.8.Preliminary analysis identifies 15 clusters with distinct CD45 immune phenotypes (figure 1). Differential gene expression analysis by hashtag antibody (treatment group) reveals 14 clusters differentially expressing key genes, including 3 clusters upregulated in DIPG compared to NML, and 2 clusters upregulated in irradiated tumors compared to SHAM and NML (figure 2). Notably, analysis demonstrates an individual cluster upregulated in FLASH versus all other groups (p = 3.07E-171). Further deconvolution of specific immune phenotypes represented by each cluster is ongoing.Abstract 91 Figure 1tSNE plot based on clustering of RNA signatures, grouped by RNAAbstract 91 Figure 2tSNE plot based on clustering of RNA signatures, grouped by hashtag antibodyOur preliminary analysis shows differential immune responses among DIPG tumors compared to NML. We also find several immune cell subsets that are unique to DIPG treated with CONV or FLASH compared to unirradiated samples. Most notably, we identify a single immune cell subset that is exclusive to FLASH alone, indicating that FLASH elicits a unique immune response in murine DIPG.


The European Early Childhood Education Research Journal (EECERJ) defines its scope as being 'multidisciplinary, embracing all related fields including psychology, sociology, child health and social work'. In this editorial for the EECERJ Special Issue on Multilingual Childhoods, we present our argument for educational linguistics to be included as a 'related field', as well as an overview of articles published between 2000 and 2020 investigating how multilingual issues have been addressed in EECERJ. A conclusion drawn from this review is that research into multilingualism in the early childhood education and care (ECEC) context draws inspiration from both educational research and linguistics. Linguistics and education are occasionally understood as two distinct research disciplines. Like most disciplines, both are characterized by the tension between tidiness and manageability on the one hand, and closeness to their object of study on the other. While linguistics has tended to move towards idealization and formalization of data, education has tended to resist calls for a formal science of learning (Brumfit 1996). Applied linguistics is the subdiscipline that has dealt with issues related to educational issues such as language teaching in formal schooling contexts. But even Pennycook (1994, 299) has claimed that applied linguistics seems to be divorced from educational theory and there has been a tendency to deal with language teaching as a predominantly psycholinguistic phenomenon isolated from its social, cultural, and educational context. Within ECEC research, linguistics and even applied linguistics seem to be almost invisible in that the research discipline itself is not explicitly mentioned. Despite this, we believe that linguistics is the basis for some of the ECEC research that deals with languagerelated issues.


The structure and mixing of impulsively started jets have heen studied in a water tank utilizing an acid-base reaction. The flow consists of a starting vortex that separates from the rest of the jet in the near field. Penetration of the jet tip scales with the square root of time, normalized by the nozzle diameter and velocity. The celerity of the jet tip is approximately one-half of the centerline velocity of a steady jet, with the same nozzle exit velocity, at the same location. Results of chemically reactive experiments indicate that the fluid in the vicinity of the jet tip mixes with the ambient fluid faster than the rest of the jet. The extent of the region near the jet tip with improved mixing becomes larger as the jet travels further downstream. The more rapid mass mixing at the jet tip implies faster momentum diffusion, which corroborates the slowing down of the jet tip in comparison with the steady jet.


Functional encryption ensures that user can access encrypted data stored over cloud in which the first step is to encrypt the data files {P1, P2,........,Pn) by the data owner using Cipher text policy ABE that result in {C1, C2,........, Cn}. Then upload the encrypted files on a cloud based storage server or on a public cloud. Once the files are uploaded on the cloud the data owner list the prospective users and send all of them an email which contains two links. The first link is to send request to the Server a key as trapdoor to retrieve the encrypted data from the storage server. On the server side the third party which is a trusted party use this email to identify that this is an authorized user and then fetch the encrypted data file. Using the email id as an attribute it decrypt the file and get a function f(Ci) of the encrypted file.


INTRODUCTION: The burnout syndrome is a result of stress on the work situation and most often concerns professions requiring emotional and direct contact with another human being. The level of empathy is closely related to the phenomenon of occupational burnout. The aim of the study was to determine the impact of socio-demographic factors of emergency services employees on the level of empathy. METHOD: In the period January–March 2018, a survey was conducted using a questionnaire — Emphatic Sensitiveness Scale (ESC) and an anonymous author's questionnaire containing questions regarding sex, age, length of employment, occupation, marital status and number of hours worked per month. The survey was addressed to 81 employees of emergency services: paramedics (n = 17) and firefighters (n = 23). The control group consisted of 16 nurses and 25 people performing non–medical professions. RESULTS: The average number of hours worked per month by the respondents was 189 ± 49. There were 50 females (62%) and 31 males (38%). The questionnaire showed statistically significant differences in perspective taking domain between the control group composed of people working in non-medical professions (25.6 ± 4.3) and emergency services professionals: firefighter (28.7 ± 3.6) vs. paramedic (29.9 ± 3.5) vs. nurse (31.2 ± 3.0), p < 0.001. It has been shown a statistically significant effect of sex on personal distress domain: male (21.4 ± 4.2) vs. female (24.3 ± 4.7), p = 0.005. CONCLUSIONS: In conclusion, our data indicates that: (1) Nurses were characterised by the highest level of empathy amongst the surveyed professional groups; (2) Females were characterised by a higher level of personal distress; (3) Variables such as sex, age, and length of employment did not affect the level of empathy.


This article combine army district hospital reality, point out that health resource optimization and combination is the impersonal need of military system and establishment adjustment, actual need of improving the utilization effect of health resource and important measure of strengthening health support ability. The basic principle of optimization and combination are: First, insist on demand oriented and stressing the key points; Second, insist on regional planning and rational arrangement; Third, insist on keeping talents and complementary advantages. The main methods of optimization and combination are: Guarantee central allocation of health resource and build regional medical treatment centre; Build medical information center; Build medical experiment research center; Utilize sanatorium resources and hospital resources synthetically; Have complementary advantages with regional resource allocation. The key points of optimization and combination are: Decision of military commission unify with benefit adjustment; Optimized allocation of health resource unify with rational utilization; Hospital development ability unify with support efficiency; new support model unify with mechanism of management.


Dermatoscopy can help to identify lesions that are suspicious for melanoma and require biopsy. In this study from Australia, the authors assessed the


A door assembly for a composite range is provided to simplify an assembly process by including only a locking ridge and a door frame as structure for preventing movement of a reflective glass. A door assembly for a composite range comprises a door glass(100), a glass supporter(200), a reflective glass(300), a door frame(400) and a cover frame(500). The door glass forms a front surface. The glass supporter is formed in rectangular frame shape with inner portion opened and coupled to the door glass in a front surface thereof. The reflective glass is mounted so that the opened portion is closed in a state mounted in a mounting ridge(240) of a rear surface of the glass supporter. The door frame is coupled to a rear surface of the glass supporter and has the inner portion consisted of a multi-hole plate. The cover frame is coupled to the glass supporter between the reflective glass and the door frame.


This article presents the findings of a descriptive content analysis of three Irish 'quality' newspapers' coverage of issues relating to the Iraq War during the period from 1 September 2002 to 31 December 2007 — The Irish Times, the Irish Independent and the Sunday Independent. It addresses the shortcoming in existing research on the Irish media's coverage of the Iraq War and also contributes to the body of research already undertaken on different international media's coverage of this war. Its central focus explores the influences that different contextually specific political, cultural and news factors have on media reportage. It is broadly situated within the agenda-setting research paradigm, but advocates a number of theoretical extensions of this paradigm. In particular, it is argued that rather than viewing media foreign news agendas as simplistic byproducts of media—political relations, they can be more usefully conceptualized as the outcomes of different processes of interaction between 'real world' cues defining the wider political environment and media factors, such as news values and sourcing strategies.


The present study aims to describe the development of different embryonic stages of Oreochromis niloticus (O. niloticus) and how apoptosis could be considered as a major physiological process associated with developmental stages of O. niloticus embryos, even reared at different environments. Embryonic development of different stages of O. niloticus was determined morphologicaly using specific software TPSDigression, apoptosis was assessed in the whole embryonic tissues using different techniques, agarose gel electrophoresis and ELISA. Apoptosis was detected in-situ at single cell level using TUNEL technique. Results showed that rate of growth correlates with apoptosis in different embryonic stages of O. niloticus. Embryonic stages which were collected from Ain Shams fish farm, showed a high rate of growth associated with different apoptotic activity than those collected from El-Abbassa fish farm. It should be noted that apoptotic activity varies according to the growth rate of different embryonic stages. The study concluded that apopotosis is a physiological process associated with embryonic development of O. niloticus and environmental factors, strongly, control apoptosis during development.


When a neurologist called Freud presented his findings on hysteria in 1895, his suggestion that it was caused by childhood sexual trauma met with angry disbelief among his colleagues. Over the next ten years he decided that the traumas must have been fantasies, and proposed a set of psychic mechanisms to explain the creation and subsequent concealment of these fantasies. The rest is history, or rather psychoanalysis.


which are not groups have been shown to have matrix representations. A method discussed by C. W. Curtis ang I. Reiner L for representing elements of a finite group of orde: n with n x n matrices has been successfully applied to the study of finite semigroups which are [~ot groups. A technique suggested to this writer by W. Stenberg 2 for the computerized study of finite semi-groups has been extended to the problem of matrix representation of finite semigroups. processes using finite element techniques have the following characteristics: a set E of elemental matrices which is combined in various ways to form a set ~ of global matrices which is used in the algorithm. E={members of elemental matrices}. G=(members of global matrices}. IE={elemental matrix member identification codes (ida)}. IG={g~obal matrix member idc}. IE={elemental matrix ida}. IG={global matrix idc}. E X IE={(e,i) le is a member of E, i is a member of IX} Define a relation ~ such that @ : E X IE÷E X IE (associates with elemental matrix members their idc). UC___B-A useful notion for proving things about pointer manipulation programs is the D(I,E), the set of all locations reachable from an initial set of locations I without taking contents of any location in the set E. Let C(X) be the set of values in all the locations in the set X, and let S(Y) be any additive function from values to locations; i.e. s(xUY) = S(X) US(Y). Then S(C(X)) are the locations immediately accessible from X and The flexibility allowed S is useful. For example S(<t,x,y>) = i_f t=0 then x else y (extended to sets in the obvious way) is permissible. If p is a pointer-valued variable, := v stores the value of v in the location pointed to by p.This paper describes and demonstrates a model, based on the well-known job shop cost-accounting scheme, for use in measuring and charging for services obtained from a computing system. The model establishes charges for use of a computing system equitably based On the actual use or monopolization of the component facilities of that system. Its dynamic nature makes it particularly appropriate for use with a multi-programmed computer system where many users are concurrently sharing the various system facilities. By providing a fair and straightforward charge or price for use of component facilities, this technique in addition to directly reflecting costs, utilizes price in its true economic …


The adsorption of ammonia and other simple molecules on an activated Eu(III) ion exchanged mordenite (Eu-M) has been studied by the measurement of the luminescence of the Eu/sup 2 +/ ion, which was produced by dehydration at 500/sup 0/C. The emission peak of the Eu/sup 2 +/ ion shifted to a shorter wavelength on exposure to ammonia and other simple molecules. The magnitude of the shift was correlated to the specific dielectric constant of the adsorbate. The quantum yield for the Eu/sup 2 +/ emission bands decreased after the adsorption of NH/sub 3/ and CH/sub 3/CN. Also, the lifetime in the Eu/sup 2 +/-adsorbate system was shorter than that in an activated Eu-M sample. The rate constant for the radiationless transitions was more sensitive to the nature of the adsorbate, and the order of the quenching power was CH/sub 3/CN > NH/sub 3/ > (CH/sub 2/NH/sub 2/)/sub 2/. 30 references, 6 figures, 4 tables.


Density, as an urban variable, is a quantitative parameter that affects both architecture and life quality, i.e., the quality of life of the inhabitants of the architecture. In this research the concept of density is extended to a three-fold meaning: density of buildings (with particular attention to density interpretation in terms of surface: FAR – floor area ratio), density of encounter (whose values are randomness and closeness), and density of uses (differentiation of activities and functions).


The article discusses the use of Design Thinking (DT) for the improvement and innovation of educational services in higher education using the SDL theoretical framework. The methodology adopted was the bibliographic review of case studies, with reference to the Scopus and Scielo databases. The cases identified were tabulated by type of use of DT and those that reported the use of DT with the participation of students underwent content analysis. Results point to little use of DT with participation of students to innovate  educational services.  Data analysis and discussion emphasizes the student's role as value  co-creator of educational services. The approach to service innovation from SDL lenses and their combination with DT brings a new look at the innovation of higher education service and contributes to broaden the possibilities of using both concepts to support processes of innovation in education.


The James Bond series has maintained its brand identity through the
 James Bond character, recurring plot elements, and its film design, in
 particular the credits sequences of Maurice Binder, Robert Brownjohn,
 MK12, and Daniel Kleinman. This chapter will examine the work of
 Binder, who created fourteen of the first eighteen Bond titles and has
 been rightly singled out as one of a new generation of title designers who
 utilized modernist aesthetics to create a specific look for the James Bond
 franchise. The chapter also asks how the digital turn, which coincided
 with the transition from Binder to Kleinman in the 1990s, has impacted
 the design and aesthetics of the James Bond title sequences.


This paper considers the ways that psychoanalysis was understood to provide a distinctive insight in to the 'problems of civilization' and a means of understanding the psychic dynamics of social groups in the anticipation of war in Britain in the 1930s. It examines the eclipsing of contemporary models of cultural attachment and social feeling, sentiment development and equilibrium of character as the basis of the effective management of social relations, as Freudian models that proposed destructive urges and aggression as the basis of character appeared more relevant to the dynamics of escalating national conflict.


In this paper, TaN thin film were deposited on ceramic substrates by D.C. magnetron sputtering. The surface morphology of two types of TaN thin film resistors were investigated by SEM. The characteristics of the TaN thin film resistor was also studied. The key point was put on the TCR of the TaN thin film resistors. The resistors were trimmed by the autoxidation process and the anodic oxidation process, and the TCR values of about +21ppm/°C and-137.3ppm/°C in average have been achieved respectively.


The results of a preliminary investigation on debris flow disasters occurred on June 20, 2003 in Puge County of Sichuan Province is presented in this paper. Based on analyses of debris flow generation, dynamic processes and in-situ evaluation of the disasters, suggestions for the prediction of such low frequency and large scale debris flow and policy of disaster relief and prevention in our country are proposed.


Consider a gain graph with abelian gain group having no odd torsion. If there is a basis of the graph's binary cycle space each of whose members can be lifted to a closed walk whose gain is the identity, then the gain graph is balanced, provided that the graph is finite or the group has no nontrivial infinitely 2-divisible elements. We apply this theorem to deduce a result on the structural geometry of PL-realizations of cell-decompositions of manifolds.


Clutch unit of the type for fixed attachment to a support flange (11) a first plate (20) or a flywheel includes a clutch plate (21), a second plate (22) or printing plate in relation to the flywheel (20) axially is movable and rotatably connected thereto, axially acting resilient means (23) for loading the pressure plate (22) toward the flywheel (20) for clamping of the clutch disc (21) and a flywheel (20) attached holding element (24), wherein the retaining element (24) consists of a hollow cap, comprising a mounting edge (30) for attachment to the flywheel (20) by means of fastening means, a jacket (31) which surrounds at least the pressure plate (22) partially, and one side with the fastening edge (30) and on the other hand with a base (32) is connected, as well as comprising a mounting zone (35, 135) for connecting the lid to the support flange (11), wherein the coupling unit (10) over the lid (24) and the support flange (11) to a driven shaft ...


The article analyzes the main types of dialect dictionaries created on the basis of Ukrainian dialects, as well as the peculiarities of the structure of the dictionary entry. In recent decades, there has been an increase in the interest of lexicographers-dialectologists in the creation of dialect dictionaries. On the example of several dictionaries in which the Hutsul dialect is presented, the completeness of the representation of dialect material in them is demonstrated. In particular, the use of illustrative material in dictionary entries is considered. The main difficulties associated with the process of creating a dialect dictionary are outlined. The article describes the problems that arise while working with the archival card index, on the basis of which a dialect dictionary is created (for example, «The Materials for the Dictionary of the Ukrainian Dialects of Transcarpathian Region" by M. Grytsak). It is noted that in recent years dialectologists have been trying to create lexicons with maximum linguistic information and detailed illustrations, using not only the respondents answers to questions from special programs or questionnaires, but also dialect texts, folklore sources, and archival materials, which made certain changes in the methodology of creating a dialect dictionary, as well as illustrating a word in a dialect dictionary. Dialectal explanatory dictionaries of a differential type, which were previously given preference, are increasingly being replaced by dictionaries of one dialect, where they represent as fully as possible all the vocabulary that they managed to register; dictionaries of one particular dialect system are becoming popular, for the creation of which large dialect texts are used. The use of different methods and sources for the creation of dialect dictionaries speaks of the prospects of such studies.


Purpose
This paper aims to investigate the influence of smooth curvature distributions on the self-noise of a low Reynolds number aerofoil and to unveil the flow mechanisms in the phenomenon.

Design/methodology/approach
In this paper, large Eddy simulation (LES) approach was performed to investigate the unsteady aerodynamic performance of both the original aerofoil E387 and the redesigned aerofoil A7 in a time-dependent study of boundary layer characteristics at Reynolds number 100,000 and angle of attack (AoA) 4-degree. The aerofoil A7 is redesigned from E387 by removing the irregularities in the surface curvature distributions and keeping a nearly identical geometry. Flow vorticity magnitude of both aerofoils, along with the spectra of the vertical fluctuating velocity component and noise level, are analysed to demonstrate the bubble flapping process near the trailing edge (TE) and the vortex shedding phenomenon.

Findings
This paper provides quantitative insights about how the flapping process of the laminar separation bubble (LSB) within the boundary layer near the TE affects the aerofoil self-noise. It is found that the aerofoil A7 with smooth curvature distributions presents a 10% smaller LSB compared to the aerofoil E387 at Reynolds number 100,000 and AoA 4-degree. The LES results also suggest that curvature distribution smoothing leads to a 6.5% reduction in overall broadband noise level.

Originality/value
This paper fulfils an identified need to reveal the unknown flow structure and the boundary layer characteristics that resulted in the self-noise reduction phenomenon yielded by curvature distribution smoothing.


Patient 1. A 34-year-old black female was admitted with a 4-month history of progressive disabling pain and stiffness of her limbs, more prominently involving the lower extremities. These symptoms were preceded by paresthesias of her hands and feet. Abnormal neurological findings included 5 strength by the MRC in the legs, clinical myokymia diffusely in the arms and legs, and absent knee and ankle reflexes. Abnormal laboratory tests included creatine kinase of 545 units on the day of admission, which was decreased to 200 units 6 days later. CSF were normal. After the diagnosis of myokymia-cramp syndrome was made, phenytoin (300 mg/day) was started with gradual resolution of rnyokymia and improvement in strength. Within 1 year she was off medication and asymptomatic.


Aquatic vegetation studies were carried out from Tuesday July 15th, 1997 to Tuesday July 22, 1997 in a sea-side aquarium- laboratory in the city of Livorno on the Tyrrhenian Sea. The investigations involved an important sea grass species Posidonia oceanica that is the main higher aquatic vegetation found in the Mediterranean Sea. Fluorescence measurements were acquired on the aquatic plants treated with different levels of Mercury and Cadmium heavy metal contamination. The measurements included steady state fluorescence and fluorescence induction kinetics, pigment extraction, and photosynthetic gas exchange rates. Fluorescence instrumentation used for the studies included the high spectral resolution fluorescence lidar System (FLIDAR$CPY), the NASA/USDA Fluorescence Imaging System (FIS), and Perkin Elmer Spectrofluorometer. Fluorescence responses showed a significant variations within the leaf as a function location from the base. Heavy metal treatments resulted in distinguishable differences in fluorescence responses.


The scope of the work presented in this thesis was to investigate the recording phenomena at very high track density and understand the requirements for reaching submicron tracks in magnetic tape. A broad study of edge effects is presented with a focus on side writing and erasing, which are critical factors for reaching narrow tracks. Different types of recording heads and magnetic tapes were investigated.


A new unburned brick was prepared from the Ti-bearing blast furnace slag as an aggregate and PVA modified by epikote as cementitious materials. The effects of modified PVA and auxiliaries on compressive strength of unburned brick were studied by the orthogonal test method. The results show that samples have better properties and low cost when the samples have a composition of slag dosage 72 %, modified PVA dosage 6%, auxiliary 1 dosage 6%, auxiliary 2 dosage 10%, water 6% and the process conditions of preparing the brick sample were mixing time 1 h, forming time 10 min, forming pressure 40 MPa, and curing time 7 d. The study reveals that the samples properties can meet the standard requirements of excellent grade products (MU20) in GB11945-1999.


"MSMEs are said to be the lifeblood of any vibrant economy and are known as the silent drivers of a nation's economy" Micro, Small and Medium Enterprises (MSMEs) represent more than 90% of all businesses & occupies a central part of the Indian economy. From Indian perspective, they provide bread and butter to many people in India & are essentially the drivers of the Indian economy. MSMEs sector has performed exceedingly well and enabled our country to achieve a wide measure for its advancement. Their contribution to economic growth, income and employment genera tion is therefore not in doubt & is really praiseworthy. Though there are many studies on MSMEs the focuses of most of the studies were on the financial aspects at the expense of the most valuable assets-the human resource. Today, Human resource management (HRM) practices are very important because its functions, practices and procedures are increasingly becoming important, considering the growth of the economy. Human resources in any enterprise, constitute an important area of study as most of the people spend a majority of their life at working place. Careful HRM creates good opportunities to ensure efficiency in the production process of goods &services that guarantee a satisfactory level of living in society. The uniqueness of this paper is the emphasis on the HRM perspective which is important for MSMEs to progress and be competit ive in India. Specifically suggests professional approach to various dimensions of HRM in the light of various constraints the MSMEs encounter. It also maps out the background, the various issues faced by MSMEs and various strategies which would help them to be more resilient. It concludes that there is informality and high flexibility in the practice of HRM and formalization of practices is essential.


The recent progress in duct acoustic research is reflected by fourteen papers which cover essentially the areas of linear duct acoustics, the characteristics of absorbent materials, and nonlinear duct acoustics. With respect to propagation in ducts, emphasis is placed on computational methods aimed at attaining effective economical modeling of propagation in variable-geometry and in hard-wall or soft-wall ducts. Computational methods developed to reduce computer processing and storage requirements are outlined, along with a wave envelope technique for reducing processing and storage needs. The latter technique is applied to the optimum segmented acoustic duct linear design. A finite difference technique is used in combination with conformal mapping to compute the optimum multisection duct linear design.


The pressure- and indentation-induced phase transformations in crystalline $(cd)$ and amorphous $(a)$ silicon are studied by using molecular dynamics simulations based on the modified Tersoff potential. The $s{p}^{3}{s}^{\ensuremath{\star}}$ tight-binding scheme is employed to gain insight into the origin of the change in conductivity during nanoindentation. The Gibbs free energy calculations predict the following pressure-induced phase transitions: $cd\text{-Si}\ensuremath{\rightarrow}\ensuremath{\beta}\text{-tin}$ $\text{Si}(\ensuremath{\beta}\text{-Si})$ (11.4 GPa); $cd\text{-Si}\ensuremath{\rightarrow}\text{high}$ density amorphous phase (HDA) (22.5 GPa); $a\text{-Si}\ensuremath{\rightarrow}\ensuremath{\beta}\text{-Si}$ (2.5 GPa); $a\text{-Si}\ensuremath{\rightarrow}\text{HDA}$ (8.4 GPa). Simulations of nanoindentation of crystalline silicon reveal discontinuities in the load-displacement curves. In the loading curves of the $cd\text{-Si}$ (100) substrate, the pop-in is assigned to the appearance of the $\ensuremath{\beta}\text{-tin}$ Si phase. During unloading, the pop-out is due to the formation of a low-density amorphous phase $a\text{-Si}$. The $a\text{-Si}\ensuremath{\rightarrow}\text{HDA}$ transformation takes place during nanoindentation of $a\text{-Si}$ in loading regime. Upon unloading the $a\text{-Si}$ phase is preserved. The structural transformations in $cd\text{-Si}$ and $a\text{-Si}$ during nanoindentation are treated in terms of triaxial and uniaxial compressions of the respective bulk samples. A change in conductivity from semiconducting to metallic during nanoindentation of the $cd\text{-Si}$ (100) and $a\text{-Si}$ slabs is explained in terms of a transformation of the localized electronic states in the band gap region. The results are compared to those of available theoretical models and experiments.


The ploidy levels of ninety Guinea yam (Dioscorea cayenensis/D. rotundata complex) cultivars identified within Benin were determined by both chromosome counting from root tip cells and flow cytometry. Three different ploidy levels (4x, 6x, 8x) were detected among the samples. Eighty cultivars were tetraploid, five were hexaploid, three were octoploid and two cultivars, 'Tam-Sam' and 'Yoube' were mixoploid with both 4x and 8x ploidy levels. Chromosome counts were in agreement with data from flow cytometry that provides an easier assay for ploidy analysis. Flow cytometry was found to be a reliable tool for rapid determination of ploidy level in yam.
(African Crop Science Journal 8(4) 2000: 355-364)


In this work, the influence of copper on amorphous type Indium-Gallium-Zinc-Oxide (a-IGZO) thin-film transistor's (TFTs) transfer curve is studied. The ID-VG curves of a-IGZO TFTs with source/drain in the structures of Cu/Ti and Ti/Al/Ti are compared. The results show that the copper greatly deteriorates the performance of the TFTs. The presence of the copper in the channel region of the device is verified by SIMS analysis. A Cu-dipping experiment is conducted by dipping devices into the solution of CuSO4 to confirm the role of copper in the deterioration of the ID-VG curves. The hypothesis is also verified through ATLAS device simulator.


The purpose of this study was to analyze students" creative personality within creativity·personality model schools and public schools in order to investigate effects on of the management of Creativity·Personality Model School. The objects of this study were different 4∼6th grade classes in two Elementary schools located in Gyeongsangnam-do G city. The experimental group was composed of 301 students Y Elementary school and the comparative group was composed of 231 students G Elementary school. Before carrying out the study, both groups took the preliminary examination about their creative personality. After three months, the experiment group and the comparison group took the post examination to compare and analyze the results. The results of this study were as follows: It was observed that the management of Creativity·Personality Model School would have meaningful effects to improve the creative personality of students. A important factor was that operated a variety program of creative personality, such as 'Rainbow School' and 'Rainbow Experiential learning'. Through this study, it seemed to conclude that the management of Creativity·Personality Model School was more effective on improving students` creative personality.


The last data in the present invention is 3GPP transmission side is the RLC layer from the RLC layer to a polling bit set to request the transmission of the status information to the RLC layer, the last data and whether the transmission window in the transmission buffer of the asynchronous mobile communication system to consider whether it was to be set. Step of the present invention, select a data unit from a buffer; Wherein the data unit and determining that occupies the last position in at least one of the buffer or the transmission window; When the data unit without accounting for the last position in the buffer, it is determined that occupies the last position within the transmission window, characterized by comprising, including the step of transmitting the polling information with the data unit. According to the present invention is, by setting the polling bit examines the last protocol data unit whether in the presence and the transmission window of the last protocol data unit in the transmission buffer, to operate the system more reliably in the transmission system of the protocol data unit is.


Botsourcing is the augmentation or replacement of human jobs by robots or other computing systems.  This practice is growing in popularity for reasons both economic and technical.  Botsourcing will seriously challenge the human workforce, and in some cases humans will find themselves working alongside robots or other "intelligent' computer systems.  In other cases, botsourcing will eliminate jobs and will force impacted humans to retrain.  This paper discusses the nature and appeal of botsourcing, as well as the challenge to human employment.


This chapter explores the use of prediction markets to generate, collect, and process information relating to a variety of environmental problems. Prediction markets, artificially constructed markets for contracts for contingent payoffs, have been used to generate projections of future conditions and outcomes in a variety of different settings. Prediction markets provide incentives for individuals to bring private and decentralized information into the marketplace through trading. This chapter proposes that prediction markets could be applied to a number of environmental problems that suffer from poor information pertaining to the causes and severities of the problems or pertaining to solutions to the problems. The general form of the proposal is a two-part instrument consisting of (1) a unitary environmental tax that is indexed to the amount of environmental harm, and (2) a cap-and-trade system of permits to pollute in the future that can be redeemed in lieu of paying the tax. The amount of the tax would be indexed each year to one or more non-manipulable environmental conditions reflecting the degree of environmental harm. This cap-and-trade system is the prediction market, and indexed tax is the measurement of the future conditions for which predictions are needed. The tradable permits to emit in the future are essentially unitary exemptions from the future environmental tax, and prices for these permits should largely reflect market expectations of the future tax level. By linking the price of permits to the future tax, and by linking the future tax to future environmental conditions, this instrument solicits and processes information and expectations of future environmental conditions.


Selecting effective features from the raw attributes is an important step in scientific and technical text classification. Feature selection aims to pick the best subset of candidate attributes to achieve superior performance of the learning algorithm. Recently, many meta-heuristic algorithms were widely developed for feature selection in classification problems. Black Hole Algorithm (BHA) is an emerging meta-heuristic algorithm, inspired by the mechanism of star motion around black holes, which has achieved excellent performance on a variety of optimization problems. A novel Binary Black Hole Algorithm (BinBHA) was proposed in this work, to enhance the efficiency of searching optimal features from the high-dimensional attributes of scientific and technical texts. In BinBHA, all operators are binary encoded without continuous-binary transformation, which makes it better for exploring the solution space of discrete problems and finding globally optimal solutions. The proposed algorithm has been compared with several alternative state-of-art methods for feature selection, and the effectiveness of the approach was evaluated on several benchmark datasets. In this paper, BinBHA was successfully implemented on an actual scientific and technical text dataset, and achieved the best performance results among other algorithms. The experimental results demonstrated that the proposed binary encoding method can improve the prediction accuracy significantly while finding the optimal solution effectively.


PurposeWine, fruits, vegetables and whole grains are the main products of a healthy diet. The purpose of this paper is to scrutinize the existence of an interesting and evocative bond among moderate intake of wine, health and well-being.Design/methodology/approachBy means of a fuzzy cluster analysis, the authors try to investigate the existence of groups of regions similar in wine consumption, subjective well-being, health and social relations. The latter are expressed through composite indicators, built and developed by Istat within the Italy ESW project's activities (equitable and sustainable well-being). The analysis also investigates how this link has evolved over time. Data are related to refer to the situations in 2010 and 2017 in 21 regions of Italy.FindingsResults obtained in 2010 seem to confirm the hypothesis of the existence of a link among moderate wine consumption, hedonism well-being and health, and in addition, findings highlight the so-called North‒South gap, that is the strong differences and economic issues among the different areas of the country. Then, outcomes obtained for 2017 appear in line with 2010 results.Originality/valueSeveral authors from medicine, economics and chemistry domain strongly suggest and demonstrate that regular and moderate intake of wine reduces the incidence of heart disease, diabetes mellitus and hormonal problems, and correlatively increases longevity. In this work, the authors develop further research step including the aspects related to personal well-being and social relations under the umbrella of a hedonism approach. Finally, results highlight the existence of an amazing tie among moderate intake of wine consumption, well-being and health.


99 5. Blishchenko I. P., Solntseva М. М. Regional. Conflicts and International Law (the Second Half of the XX – the Beginning of the XXI Century). Moscow: Horodets, 2005. 6. Banasik M. How to Understand the Hybrid War. Securitologia. No 1. 2015. P. 19–34. 7. Big Interpretive Dictionary of Modern Ukrainian Language / Busel V.Т., Ed. Kyiv: Irpin: VTF «Perun», 2004. 8. Jacobs A., Lasconjarias G. NATO's Hybrid Flanks: Handling Unconventional Warfare in the South and the East. Research Paper (NATO Defense College). No 112. 2015. P. 1–12. 9. CIA Helped To Mine Ports In Nicaragua. URL: https://www.washingtonpost. com/archive/politics/1984/04/07/cia-helped-to-mine-ports-in-nicaragua/762f775f-6733-4dd4-b6928f03c8a0aef8/?utm_term=.d37a2ab0b8e2. 10. Militarv and Paramilitary Activities in und against Nicaragua (Nicaragua v. United States of America). Merits, Judgment. I.C.J. Reports. 1986. P. 14. 11. Guzman T. A. The CIA's Dirty War in Nicaragua. URL: https://www. globalresearch.ca/the-cias-dirty-war-in-nicaragua/5629008. 12. Linton A. Fair Trade from the Ground Up: New Markets for Social Justice. Seattle: University of Washington Press, 2012. 13. Landis F. CIA Psychological Warfare Operations. Case Studies in Chile, Jamaica and Nicaragua. Science for the People. No 14. 1982. P. 6–11. 14. Metoyer C. C. Women and the State in Post-Sandinista Nicaragua. Boulder: Lynne Rienner Publishers, 2000.


In this paper, we propose a vision control strategy to perform automatic microassembly tasks in three- dimension (3-D), and develop relevant control software. Specifically, using a 6 degree-of-freedom (DOF) robotic workstation to control a passive microgripper to automatically grasp a designated micropart from the chip, pivot the micropart, and then move the micropart to vertically insert into a designated slot on the chip. In the proposed control strategy, the whole microassembly task is divided into two subtasks, micro-grasping and micro-joining, in sequence. To guarantee the success of microassembly and manipulation accuracy, two different two-stage feedback motion strategies, the pattern matching and auto-focus method are employed, with the use of vision-based control system and the vision control software developed. Experiments conducted demonstrate the efficiency and validity of the proposed control strategy.


Abstract The present arrangement of franchising is a very popular business form. It is a very dynamic form of making business. The form is very modern and conservative at once. It′s modern enough and at the same time approved, to represent the possible visionary way of the entrepreneurship in the 21st century. Franchising has become a means of growth across many different industries, including business and financial services, beauty, health, sport, various services, food, medical, recreation and many others. Our effort might understand how the franchising performance drivers applied in the microeconomic parts work and how important it is for franchisor and the franchisee, as well.


Small satellite missions open the space environment to a wide range of diverse missions. NASA has indicated that these satellites will be a paradigm shift for NASA and the larger space community. Currently, most of these small satellites cannot utilize a propulsion system due to size and mass constraints; however, research being performed at the Missouri University of Science and Technology may soon change that. The Missouri S&T Satellite Research team is in the process of developing two CubeSat missions that will validate a multi-mode micropropulsion system developed in collaboration with the Missouri S&T Aerospace Plasma Laboratory. Unique challenges to these missions include packaging the propulsion system and validating its performance on orbit. Methods of thruster performance validation being considered include comparison of on-orbit pressure, voltage and temperature telemetry to ground test data and comparing expected orbit/attitude changes resulting from maneuver executions to the actual changes estimated from downlinked spacecraft telemetry. A final mission Concept of Operations is developed to facilitate an effective evaluation/validation of thruster performance. INTRODUCTION According to NASAs Small Satellite Missions program, "Through technological innovation, small satellites enable entirely new architectures for a wide range of activities in space with the potential for exponential jumps in transformative science." Steve Jurczyk, associate administrator for NASAs Space Technology Mission Directorate, cites small satellites as a "paradigm shift for NASA and the larger space community." Similar to the development of the cell phone technology in the early 2000s, small satellite capabilities are developing rapidly and have the potential to change the space industry by increasing launch opportunities through both reduced cost and fewer size constraints. Additionally, this technology has opened the testing ground of space to organizations, such as universities, not previously capable of supporting more traditional (larger) spacecraft. Figure 1 shows the increase in small satellite missions over the last twenty years. The 2015 NASA Small Spacecraft Technology State of the Art report states, "As propulsion technology matures, more small spacecraft missions will incorporate propulsion systems on board allowing for more complex mission architectures." Additionally, the AF Technology Horizons report lists "Fractionated, Composable, Survivable, Autonomous Systems" as a technology grand challenge, and specifically calls out "Rapidly Composable Satellite Systems: Satellites that can be assembled, tested, and launched within days of operational requirement, based on a plug-and-play/open-architecture approach using standards for self-describing components within a discoverable and autoconfiguring system" as a major focus. The need for propulsion systems for smallsats is becoming more urgent as the demand for these spacecraft and their missions expand and diversify; however, due to inherent size, mass, and power limitations, propulsion systems are not commonly available for smallsats and CubeSats. It is therefore necessary to develop and validate the performance of such a propulsion system that can be easily inMorton, Withrow-Maser 1 31 Annual AIAA/USU Conference on Small Satellites Figure 1: Number of Smallsat Missions from 1994 to 2013 tegrated into a CubeSat form factor. As evidenced by the reports cited above, propulsion system technology to expand CubeSat mission opportunities is relevant and desired in many areas of the space community. BACKGROUND The small satellite research team at the Missouri University of Science and Technology (Missouri S&T) is currently working toward the integration of an innovative new multi-mode micropropulsion system (in collaboration with Missouri S&Ts Aerospace Plasma Laboratory) into a CubeSat form factor. Two missions will be used to demonstrate and validate this technology in the space environment. The first mission, designated M (multi-mode mission), is sponsored by NASAs Undergraduate Instrumentation Program (USIP) and will provide flight heritage for the custom propellant and confirm thruster performance based on temperature, voltage, and pressure readings taken while operated on-orbit. The M-SAT team will then expand this concept to a 6U CubeSat (APEX, Advanced Propulsion EXperiment) through the Air Force Research Labs University Nanosat 9 Program (UNP) that will allow the further characterization of thruster performance by measuring orbit/attitude changes and comparing these to the expected changes based on thrust measured from ground testing. OBJECTIVES The capabilities and operational characteristics of the multi-mode propulsion system will be demonstrated on the spacecraft by achieving two objectives: (1) successful integration of multi-mode thruster technology into a small satellite architecture and (2) determination of on-orbit performance of the multi-mode thruster during chemical and electric mode burns. These objectives will be demonstrated by the execution of an electric mode burn followed by a transition and execution of a chemical mode burn of sufficient duration to reach expected steady state temperature. For the second mission (APEX), the objectives will be further exhibited by the execution of an electric mode burn of sufficient duration to quantify orbit change (unlike the first mission, which will not generate sufficient thrust to induce a measurable orbit change). Minimum mission success criteria include: performing a chemical burn for a duration of at least five seconds, performing a burn in the electric mode for a minimum of thirty seconds, and then repeating at least one mode a second time to demonstrate the multi-mode capability. BASIC FUNCTIONALITY/DESIGN One unique aspect of this propulsion system is the ability to package two different propulsion modes in a CubeSat. This provides mission flexibility prior to Morton, Withrow-Maser 2 31 Annual AIAA/USU Conference on Small Satellites Figure 2: Multi-Mode Thruster Location in the APEX CubeSat launch and even on orbit. Few flight-ready CubeSat thrusters are available on the open market at this time. Typically, CubeSats cannot provide adequate volume, mass, or power allocations for a single thruster, let alone two. The Missouri S&T thruster to be demonstrated is a single thruster, capable of operation in both chemical and electric modes that has a mass equivalent to a single, commercially available, chemical or electric CubeSat thruster. This creates the possibility for the thruster to be packaged in smaller spacecraft that could not support two systems and to optimize the use of the onboard propellant by switching between modes. This ability is achieved by the team's unique hardware design and custom propellant (Figure 2). The multi-mode propulsion system packages two types of propulsive systems into a single set of hardware using the same propellant: a high thrust, low specific impulse chemical mode and a low thrust, high specific impulse electrospray mode. Preliminary testing shows the chemical mode will produce on the order of a newton of thrust with a specific impulse of 180 seconds, and the electrical mode will produce approximately 0.25 millinewtons of thrust with a specific impulse of 800 seconds (Figure 3) in the APEX mission configuration. Performance will be determined through analysis of downlinked on-board diagnostics and orbit telemetry data and compared with data from ground testing. Pressure will be measured with pressure transducers located in the feed line and the thruster will contain thermal couples located in key areas of interest to record temperature readings at a rate of 1 Hz during chemical mode burns. Thruster emitter and extractor voltages will be measured by voltage dividers on the digital circuit board at a rate of 1 Hz during electric mode burns. On-orbit pressure, temperature, and voltage readings will be compared to pre-launch ground test data. Expected pressure, temperature, and voltage values from these sensors are approximately 200 psi, 1900 K, and 1.5 kV, respectively. Figure 3: Chemical and Electrospray Modes Morton, Withrow-Maser 3 31 Annual AIAA/USU Conference on Small Satellites The performance characteristics that will be evaluated include thrust, specific impulse, continuous burn time performance, longevity, and the power requirements for each mode along with the ability to switch between modes without performance degradation or other limitations/anomalies. PROPULSION FEED SYSTEM The propulsion system will be integrated into both a 3U structure and 6U structure, demonstrating that such propulsion systems can be practically implemented into most smallsats. Two challenges must be addressed for successful integration of the propulsion system into the satellite: packaging the system to fit within the volumetric constraints of the structure and sourcing/qualifying a vessel to store the propellant. The propulsion system hardware must be as compact as possible as the CubeSat structural envelope only contains 3,000 cm of total volume for the 3U M and 6,000 cm for the 6U APEX (Figure 4). Current methods for conserving volume include optimizing tubing size and feed system configuration (Figure 5). There are many challenges associated with packaging a propulsion system into a CubeSat including generating sufficient power and voltage, determining/controlling attitude of the spacecraft on-orbit, thermal management, and validating the performance of the thruster. One key challenge is providing the power required by the thruster system and the voltage required for the electric mode without denying power to other subsystems of the spacecraft. During the electric burn mode, the satellite requires 3400 volts in a compact circuit. A second challenge of providing this voltage is reducing the size of a power processing unit such that it fits within a 3U or 6U form factor with the o


In this paper, we prove the existence and the H\"older continuity for solutions to the complex Hessian equations on unbounded domains


The article analyzes the main factors and trigger reasons of development of landslide processes on the southern slope of the Psekhako Ridge in the valley of the Achipse River (a right tributary of the Mzymta River) in the North-West Caucasus and their modern dynamics. It is shown that moistening the upper part of the section (due to long-lasting rains and snowmelt) and strong seismic motions play the main role in their natural activation. It is noted that there is high probability of formation or activation of landslides in the autumn-winter-spring period due to extremely large amount of atmospheric precipitation. Trigger schemes of development of landslide deformations in the surveyed area are systematized and described.


: The employer's insolvency entails, in addition to the potentially devastating economic consequences of output reduction and the disruption of economic relations, adverse social costs for employees – the loss of jobs and earnings. It is not only the employee and his or her family who suffer a great loss, but the whole community. Thus, society faces the serious question of how to ensure the payment of wages to employees in the case of insolvency and provide a solid framework with which countries can find durable solutions, effectively organise and manage the protection of workers' claims. This paper analyses the achievement in developing European and national systems of protection of workers' claims in cases of insolvency, and shows the progress made by EU countries in arriving at a balance of interests between employers, employees and society in the protection of outstanding claims of employees in the event of their employer's insolvency.


Acromegaly produces a series of complications and a 2to 3-fold increase in mortality, especially from vascular causes. From the functional point of view, the aim of treatment is to reduce growth hormone (GH) hypersecretion and return GH values to below 1 ng/ml after oral glucose load, as well as to control concentrations of insulin-like growth factor (IGF-1). From the anatomical point of view, the aim is to remove the causative adenoma while preserving the remaining pituitary function as far as possible. Factors predictive of a favorable outcome are not clearly defined but normal GH and IGF-I concentrations after surgery are the most widely accepted. Criteria for hormonal control after treatment have progressively changed and are based on increasingly lower GH values after oral glucose load, lower than 0.1 ng/ml, and normal IGF-I values. These criteria are not conclusive but a definitive consensus may soon


Generating specific, robust innate immune responses to different bacteria is vital for animal survival. Here, we address the role of transforming growth factor β (TGF- β) DBL-1 in regulating signature host defense responses in Caenorhabditis elegans to human opportunistic Gram-negative and Gram-positive pathogens. Canonical DBL-1 signaling is required to suppress avoidance behavior in response to Gram-negative, but not Gram-positive bacteria. SMA-4/co-Smad acts independently of other DBL-1 core signaling components to suppress avoidance to Gram-positive bacteria, and sma-4 expression is specifically induced in response to Gram-positive bacteria. DBL-1 signaling differentially regulates expression of target innate immunity genes depending on the pathogen. Animals activate DBL-1 pathway activity in response to Gram-negative bacteria and repress it in response to Gram-positive bacteria, demonstrating bacteria-responsive regulation of DBL-1 signaling. These findings highlight a central role for TGF-β and identify a novel role for a co-Smad in tailoring a suite of bacteria-specific host defenses.


The Karlhede classification indicates that it may be necesssary to go to the seventh covariant derivative of the Riemann tensor in order to classify a general type-D nonvacuum spacetime. The authors investigate the field equations directly to show that the worse case cannot in fact occur and so reduce the derivative bound from 7 to 6 for this class of spacetimes.


An adaptive H-infinity tracking control is proposed for a z-axis microgyroscope with system nonlinearities. All the signals can be guaranteed in a bounded range, and tracking error is uniformly ultimately bounded, an H-infinity tracking performance is also achieved to a prescribed level. Adaptive control methodology is integrated with H-infinity control technique to achieve robust adaptive control, and adaptive algorithm is used to estimate the unknown system parameters. Simulation studies for microgyroscope are conducted to prove the validity of the proposed control scheme with good performance and robustness.


Isn't it obvious? The Constitution prescribes an explicitly political process for the nomination, confirmation, and appointment of US Supreme Court justices and lower federal court judges. The president has the exclusive power of nomination and may exercise that power on the basis of any criteria he or she sees fit. The Senate has the power to provide its "advice" and-if it wishes-its "consent" to such a nomination. The Senate, too, may exercise its advising and consenting (or nonconsenting) power on the basis of whatever criteria and in whatever manner senators think appropriate.2 Ultimately, the two sets of political actors must come to an agreement: the president can make a judicial appointment only with the Senate's consent. The political-constitutional judicial appointment process is inevitably, and necessarily, an occasion of political constitutional interpretation. The nomination and consent powers are occasions for the exercise by the president and the Senate of their respective independent prerogatives of constitutional interpretation, and rightfully can be used to advance those political actors' respective


An efficient three-step route for the synthesis of N-1 alkyl/aryl-substituted hydantoins was developed from inexpensive commercially available substrates. The reaction of amines with cyanogen bromide takes place to give monoalkyl/aryl cyanamides. This on treatment with methyl bromoacetate in the presence of sodium hydride in tetrahydrofuran affords methyl N-cyano-N-alkyl/arylaminoacetate, which undergoes hydrolysis and cyclization in the presence of 50 % H2SO4 to afford N-1 substituted hydantoins in very good-to-excellent yields. Wide varieties of final products having primary, secondary, tertiary, and aryl substituents at the N-1 position were successfully synthesized by this method. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)


This thesis deals with issues regarding energy efficiency of building related pump and
fan drive systems. Different Induction Motor (IM) and permanent magnet motor drive
systems are analyzed with focus on energy efficiency. A 4-pole, 4kW IM is the focus
of the IM investigation, where different motor efficiency labels, (eff1/IE2, eff2/IE1 and
eff3), different control strategies and switching schemes of the frequency converter are
analyzed. Simulations as well as measurements are performed and a close correlation of
the results is found. Furthermore, efficiency consideration regarding sizing of the IM for
a given load are analyzed. It is shown that an oversized IM gives a higher efficiency than
using one with the proper rating, provided that an adequate control of the motor supply is
used.
A commercially available 375W BLDC and a 4kW PMSM are analyzed using FEM
calculations coupled with circuit simulations, evaluating a large range of current control
strategies.
It is shown that different zero voltage vector placements have a large impact on the
iron losses in the motor as well as on the switching losses in the converter, especially at
light load. It is further shown that the efficiency of a BLDC motor can be increased at
rated operation by controlling it as a PMSM.
A comparison of inner and outer rotor BLDC motor is done. It is found that the efficiency
easily can be increased for the 375W BLDC motor by changing the design to
an outer rotor motor. It is shown that the outer rotor motor is more suitable when using
ferrite magnet materials, increasing the potential of making a more energy efficient motor.
Furthermore, the impact of iron grade and magnet material is quantified with respect to
energy efficiency and power density.
An investigation of the energy efficiency difference between a 1.2kW BLDC and a
1.2kWPMSM motor is carried out. Two motor types are designed and constructed, showing
that the BLDC motor has the highest efficiency in the whole operating range, as well
as the lowest losses in the inverter stage due to decreased switching losses. The simulation
result also verifies the modeling methods which includes a good accuracy regarding the
iron loss modeling.
The simulation results of the IM are used in order to analyze the potential saving for
different load profiles. The general conclusion is that economical savings will be made
iii
during the life time of the drive system, both for an IM and frequency converter replacement.
The analysis also show that the choice between an eff2 and eff1 IMalways generate
the highest energy saving for the eff1 IM in economical terms, for the given load profiles,
including the increased cost for an eff1 motor. The potential savings between a 4kW IM
and a 4kWcommercially available PMSM are also quantified. It is shown that the PMSM
in general is the best choice, for the given load profiles, providing an annual energy saving
of 700-2600kWh. Finally quantification of the potential savings between a 375W IM, a
375Wcommercially available BLDC motor and a proposed 375WBLDC outer rotor motor
are presented. The result presents an annual saving of 200-400kWh when replacing a
commercially IM with the BLDC motor. In addition, 200-400 kWh can be saved annually
using the proposed BLDC motor design compared with the original BLDC motor.


Abstract Recently a consensus has developed that the Big Five traits of personality (Neuroticism, Extraversion, Openness, Agreeableness, and Conscientiousness) are an adequate taxonomy of individual difference traits. However, despite this consensus and the often impressive predictive results of trait research, very little research has been done on a key question—How do traits work at the level of proximal mental processes to causally determine behavior? We argue that the constructs of the cognitive approach to personality (e.g., beliefs, expectancies, and subjective values) can be used to provide proximal, causal explanations of individual differences. Two studies are reported demonstrating the initial steps in this effort. Study 1 ( N = 83) used think-aloud assessment techniques to measure the beliefs of subjects. These interviewer-assessed beliefs were then shown to be significantly correlated with individual differences in standard self-report personality questionnaires. Study 2 assessed subjects' ( N = 86) beliefs via a self-report measure and found beliefs to be significantly correlated with scores on standard personality questionnaires. We argue that individual differences along the broad trait dimensions of the Big Five can be explained via individual differences in general beliefs people hold about themselves and the social world. Future directions and limitations of this approach are discussed.


Introduction Bacteriuriaof pregnancyis acommoncondition,affecting betweentwo and 10 per cent of pregnant 12 I' II . . h women ". t IS usua y asymptomaticill t ese cases,but the evidencestrongly indicatesthat, in contradistinctionto bacteriuria in non-pregnant women,it rarelydisappears pontaneouslyand may indeedlead toproblemslater in pregnancy.Treatment is given mainly to preventthe 30 per cent incidenceof pyelonephritisin untreatedbacteriuric pregnantwomen, and, more controversiaIlj' lowbirthweight infants and perinatal deaths, . The concensusof opinion is that all pregnantwomen shouldbe screenedfor bacteriuriaand that women with proven bacteriuria of pregnancyshould be treatedwith a five to sevenday courseof appropriate, safeantibiotic. Amoxycillin (or ampicillin) and nitrofurantoinare popularchoicesfor the treatment of bacteriuriaof pregnancybecauseboth arerecognised as safe to use in pregnancy.Otheroral agents such asco-trimoxazole,trimethoprimand nalidixic acid are contraindicatedin pregnancy", In recent years,the position of amoxycillin as a firstchoice agenthasbecomelesssecurebecauseof the increasing incidenceof resistanceof E. coli, the mostcommon pathogenin bacteriuriaofpregnancy:the level of resistanceis now about 30-40 per cent throughoutthe UK. A problemwith nitrofurantoin is its propensityto causenauseaand vomiting, and it might beexpectedthatthesesideeffectswould be exaggeratedin early pregnancy. However, it is claimedthat themacrocrystallineform of nitrofur-


The article shows the content of the notion of literacy and educational level of city population of Ciscaucasia in 1945-1959 by the example of Krasnodar and Stavropol regions. The author pays the main attention to the changes in the education sphere during the post war period and to the influence of these reforms on every day life of city population.


Psychiatry research has long experienced a stagnation stemming from a lack of understanding of the neurobiological underpinnings of phenomenologically defined mental disorders. Recently, the application of computational neuroscience to psychiatry research has shown great promise in establishing a link between phenomenological and pathophysiological aspects of mental disorders, thereby recasting current nosology in more biologically meaningful dimensions. In this review, we highlight recent investigations into computational neuroscience that have undertaken either theory‐ or data‐driven approaches to quantitatively delineate the mechanisms of mental disorders. The theory‐driven approach, including reinforcement learning models, plays an integrative role in this process by enabling correspondence between behavior and disorder‐specific alterations at multiple levels of brain organization, ranging from molecules to cells to circuits. Previous studies have explicated a plethora of defining symptoms of mental disorders, including anhedonia, inattention, and poor executive function. The data‐driven approach, on the other hand, is an emerging field in computational neuroscience seeking to identify disorder‐specific features among high‐dimensional big data. Remarkably, various machine‐learning techniques have been applied to neuroimaging data, and the extracted disorder‐specific features have been used for automatic case–control classification. For many disorders, the reported accuracies have reached 90% or more. However, we note that rigorous tests on independent cohorts are critically required to translate this research into clinical applications. Finally, we discuss the utility of the disorder‐specific features found by the data‐driven approach to psychiatric therapies, including neurofeedback. Such developments will allow simultaneous diagnosis and treatment of mental disorders using neuroimaging, thereby establishing 'theranostics' for the first time in clinical psychiatry.


In May, 2005 we were invited to collaborate in the investigation of a neurological disease in a European Burmese* kitten tentatively diagnosed by pathologists at the University of Illinois, College of Veterinary Medicine as a lysosomal storage disease. Based on characteristic pathological changes in brain consistent with a lysosomal disease, we examined tissues and confirmed that the lesions were those of the gangliosidoses. We performed biochemical analyses which identified the storage material as GM2 ganglioside and found a deficiency of the enzyme hexosaminidase. Unfortunately, none of the 3 mutations that we had previously defined for the feline GM2 gangliosidoses matched with these Burmese kitten's DNA. We then searched for a unique error in the Burmese hexosaminidase gene (DNA) and discovered yet another mutation causing feline GM2 gangliosidosis, the 4 to date (see Table 1). Based on our extensive experience with the feline gangliosidoses, we believed that this discovery had substantial significance for the European Burmese breed. Therefore, we tested a few Burmese families, on a limited scale, which confirmed that our molecular test was able to detect carriers. Discovery of the exact mutation responsible for this disease gave us the opportunity to develop a laboratory procedure which could be used to perform molecular screening to detect carriers among Burmese breeders. Results of this initial screening and our recommendations for broad molecular testing to eliminate this inherited disease are discussed below.


Reviewing Flank pains common etiology and pathogenesis,dialectical analysis and pathogenic factor.Think of the dialectical type of Flank pains including:the exogenous attacks,depressed,blood stasis block,phlegm retention block,yin deficiency of liver and kidney,be distressed about diet,Pathogenic viruses.


With the continuous development of the domestic financial market,program trading has received more and more attention. At present,most domestic program traders have not established a complete system of testing and optimization. Most of them just uses the method of backtesting instead,which can easily lead to excessive of historical data curve overfitting,but the overfitting is not equal to optimization. This paper innovative constructed a relatively complete system,including six process,design trading strategy,strategy programming,preliminary testing,optimization,step-forward analysis,trading. Through this system we can get the degree of the risk of trading model and the stability of strategy,as well as the key element of the sound trading strategy,relatively uniform distribution of profit,relatively stable ratio of the times of gains and losses,a group of continuous and smooth optimal parameters set,adaptability in different types of markets and the risk can be controlled.


The qualitative model of far-infrared polypropylene and far-infrared polyester are established with near-infrared spectroscopy technology and PLA method.The experience indicates that this method can do qualitative analysis for far-infrared fiber rapidly and accurately.


In a world which is primarily split between a few haves and majority of have-nots, tensions, diversities, self-centered vision, violence, terrorism and consumerism are creating a dreadful scenario of a bleeding world and blood splattered humanity. Many schools have been searching the reasons of depreciation in moral values and they have been working for developing good moral values among the students. The lack in moral values and the unhealthy attitudes of students is the main reason of having problems in several schools. They have been realizing the importance of moral education in school. Moral Values are the worthy ideals or principles that one follows to distinguish the right from the wrong. These ideals or virtues are considered worthy in building up the character of an individual. Moral responsibility is intimately related to our reactions to one another. Dealing with values and moral issues is recognized as integral part of teachers' roles. Teacher has an important role in inculcating moral values in students. Schools therefore can play a bigger role as a child spends most active part of his day in school. Also, it has been seen that children are more compliant to the rules and regulations of the school than the society. In recent years, schools across the country have adopted several skill-development and classroom strategies that are related to character formation. How we live our life is the ultimate choice we make.


This paper proposes a new commit protocol for real time distributed database systems, dependency sensitive shadow SWIFT (DSS-SWIFT) protocol where the cohort forks off a replica of itself called a shadow, whenever it borrows dirty value of a data item, and if, the created dependency is abort type as compared to creating shadow in all cases of dependency in shadow PROMPT. Also the health factor of cohort is used for permitting to use dirty value of lender rather than health factor of transaction as whole. The performance of DSS-SWIFT is compared with PROMPT, 2SC and SWIFT protocols for both main memory resident and disk resident databases with and without communication delay. Simulation results show that the proposed protocol improves the system performance up to 7% as transaction miss percentage


This article analyses the process and outcomes of Ghana's 2008 elections, which saw the National Democratic Congress replace the New Patriotic Party and thus an alternation of ruling party for the second time since (re)democratization in the early 1990s. It argues that Ghana's democratic political system survived the closeness and intensity of the 2008 elections because it has developed stabilizing characteristics: an independent Electoral Commission and transparent electoral processes, integration of the political elite alongside the creation of norms and institutions structuring elite behaviour, and the institutionalization of political parties. The closely competitive elections are the result of a two-party system where voters and political elites are mobilized around two political traditions. These political traditions provide ideological images, founding mythologies and political styles for the parties. Thus, Ghana is different from several African countries where parties split or form around leaders, who bring their popular support base with them. It is also different in that elections are not dominated by ethnic politicization, because the two main parties in Ghana have a strong political support base in most regions and party identification is based on cross-cutting social cleavages of which ethnicity forms only one part.


Abstract The quality of freshwater at any point on the landscape reflects the combined effects of natural and anthropogenic processes along hydrological pathways, for which the process relations may be cyclical (inter-dependent and/or periodic) and cascading. Local, regional, and global differences in human activities (e.g. mining, industry, agriculture, waste treatment and disposal), climate, and streamflow, are considerable, which, in turn, cause varying effects on water quality and quantity. Natural characteristics also greatly control human activities, which then affect the natural composition of water. These cause-and-effect relations produce uncertainty in water-quality estimates, because they are difficult to quantify. For example, although rock type is a primary control on water quality, annual dissolved major-ion yield estimates from empirical relations using rock type, precipitation quantity, population density, and temperature for large rivers in the US, are precise only to one order of magnitude, which in part is due to nonlinear responses of large non-homogeneous areas. Human activities, as reflected by land-use, can likewise be used to qualitatively indicate differences in constituent concentra-tions, particularly for constituents that are primarily controlled by non-point sources, e.g. nutrients and pesticides. However, the large concentration varia-tions prevent an accurate estimate. For many naturally occurring substances, uncertainty of estimated concentration or yield is larger for constituents primarily derived from point sources than from non-point sources, until the major point sources and related contributions are known. Also, uncertainty of the estimates of average constituent concentration or yield decreases with increasing averaging time, e.g. a predicted annual flux is more precise than an instantaneous or daily flux


Benchmarking can be an effective way of helping organizations to deliver better services through continuous improvement. The concept of benchmarking has been extensively applied to the construction industry in recent years to enhance the performance of the project delivery process. Success is hard to achieve, especially for a construction project delivered by an innovative procurement method – design and build, and the identification of critical success factors can enable project team leaders to make improvements in some particular areas. This paper aims to establish a conceptual framework of critical success factors (CSFs) for design‐build projects in construction. From the framework, it is hypothesized that project success of a design‐build project is a function of the interaction among project characteristics, project procedures, project management strategies, project‐related participants, project work atmosphere and project environment. The CSFs so identified can provide practitioners and academics with a better understanding of running a design‐build project successfully to develop a benchmark for the D&B project delivery process.


Psychiatric advance directives (PADs) document a patient's advance instructions (AIs) for treatment and/or designation of a potential proxy decision maker. Approximately 50% of a total of N=167 U.S. psychiatrists who completed a mail survey of their attitudes and views regarding PADs had a favorable opinion of a law authorizing AIs, whereas two-thirds of psychiatrists endorsed proxy decision making legislation. However, 42% perceived important barriers in the service system that would prevent effective implementation of PADs, while 30% considered clinical factors to be important barriers to implementation. Psychiatrists who are correctly apprised of applicable state mental health law are generally more supportive of PADs; they may be more willing to support PADs if they are educated about key aspects of PAD legislation.


For decades economic growth determinants have been the centre of attention among theoretical and development economists. Theoretical economists have built models of economic growth, while development economists were concerned about how these growth models behave in the long run. Previouslyresources were considered as an engine to growth, but they were prone to diminishing returns. The more recent models emphasized the role of knowledge augmented labor which may defy diminishing returns. For this, human capital is proposed as one of the main ingredients to economic growth as proposed by both neo-classical and new growth models. This studyanalyseswhether there is a precedence of the law of diminishing returns in sixty-six lower-income nations of the world.And determine whether the indicators of human capital index (HCI) can ease this diminishing return. The HCI is developed into four sub-indexes which are Capacity, Deployment, Development and Know-how. We used the robust OLS method to find how therefour sub-index of human capital work in this group of countries. The results show that the convergence hypothesishints atthe law of diminishing returns for sample countries. But by investing in human capital, or one of its sub-components, the intensity of diminishing returns will be eased.


Froese, F. J., Pak, Y. S., & Chong, L. C. (2007). Integrating organizational culture and human resources in cross-border acquisitions in South Korea. Paper presented at Academy of Management Annual Meeting, August 2007, Philadelphia


A novel piece of software is presented to connect Abaqus, a sophisticated finite element package, with Matlab, the most comprehensive program for mathematical analysis. This interface between these well-known codes not only benefits from the image processing and the integrated graph-plotting features of Matlab but also opens up new opportunities in results post-processing, statistical analysis and mathematical optimization, among many other possibilities. The software architecture and usage will be appropriately described and two problems of particular engineering significance addressed to demonstrate its capabilities. The source code, detailed documentation and a large number of tutorials can be freely downloaded from www.abaqus2matlab.com.


Nano-rod calcite was discovered in a loess-paleosol sequence with the TEM investigation for the samples from the Luochuan section. The diameter of the calcite is 30~50 nanometer and the length from hundreds nanometer to several micrometer. Nano-rod calcite crystals are round fibers with varying thicknesses. The crystals are bended along the direction of the crystal length. They sometimes have interlaced arrangement, and arborescent or frame forms. The EDS reveals small amounts of magnesium, phosphorous and sulfur. Morphology and composition analysis indicate that the formation of the nano-rod calcite is involved in matter derived from microorganisms and mineralization. The forming condition of the nano-rod calcite should be an indicator of paleoclimate, paleoenvironment and paleoecology. Therefore, the discovery of nano-rod calcite in the loess-paleosol sequence provides a new clue for reconstructing the paleoclimate and is of significance in the research of nanometer minerals in environment, genesis of carbonate in loess and paleoclimate reconstruction.


It is said that Emerson is not a philosopher. I find this denegation false or true according as it is said in blame or praise-according to the reasons proffered. When the critic writes of lack of method, of the absence of continuity, of coherent logic, and, with the old story of the string of pearls loosely strung, puts Emerson away as a writer of maxims and proverbs, a recorder of brilliant insights and abrupt aphorisms, the critic, to my mind, but writes down his own incapacity to follow a logic that is finely wrought. "We want in every man a long logic; we cannot pardon the absence of it, but it must not be spoken. Logic is the procession or proportionate unfolding of the intuition; but its virtue is as silent method; the moment it would appear as propositions and have a separate value, it is worthless." Emerson fulfills his own requisition. The critic needs the method separately propounded, and not finding his wonted leading-string is all lost. Again, says Emerson, "There is no compliment like the addressing to the human being thoughts out of certain heights and presupposing his intelligence"--a compliment which Emerson's critics have mostly hastened to avert. But to make this short, I am not acquainted with any writer, no matter how assured his position in treatises upon the history


Although the home team advantage is known to exist in many sports, there are nuances of the advantage that are less well understood. In this paper, we investigate various aspects of the home team advantage including changes in the advantage over time, the relationship of the advantage to the overall scoring rate and differential advantages within leagues. The analysis is mainly based on descriptive statistics and is confined to the home team advantage pertaining to the National Hockey League and the National Basketball Association.


Objective:To investigate the mechanism of anti-tumor effects of curcumin on cervical carcinoma HeLa cells.Methods: Growth inhibition rates of HeLa cells were measured with MTT method.The cell cycle distribution and apoptosis were detected by flow cytometic analysis.In addition,apoptosis was detected by Hoechst3358/PI fluorescent staining and the expression of Bcl-2 and Bax protein were detected by using western blot assay.Results: Curcumin inhibited the proliferation of HeLa cells in a does-and time-dependent manner.The cell growth was arrested at S stage.And aneuploid peak was observed by FCM.Fluorescent staining can detect the apoptotic cells.The expression of Bax was increased and the Bcl-2 was unchanged.Conclusion: Curcumin not only inhibits proferation but also induces apoptosis of HeLa cells.The possible mechanism is related with the increasing of Bax.


The health care of those who work in remote places associated with hostile environments is reviewed, concentrating on the offshore oil industry and Antarctic populations. An understanding of associated environmental hazards is essential for adequate health care and particular attention is paid to the hyperbaric environment and to environmental heat and cold. The basic medical problems in remote health care are evaluated in three related studies. The first examines 2,162 personnel who required medical evacuations from the offshore structures of four North Sea operating companies, the second with 5,894 presentations from offshore at the A&E department of Aberdeen Royal Infirmary, while the third examines 100 annual medical reports from British Antarctic Survey stations.


This article seeks to explore notions regarding the conceptualization of culture in the field of Christian religious education. These conceptualizations are central to understanding the social nature of faith communities and the role of religious educators as they respond to this nature. The author proposes that the faith community is intercultural in that people with distinct cultural perspectives come together to forge a shared religious identity. Consequently, the vocation of the religious educator is presented as a call to be a specactor1, a practitioner who constantly assesses his/her own cultural orientations in relation to those of the learners. The article concludes the paper with some suggestions on how to develop a contrastive pedagogy that takes into account both the intercultural dynamics of the Christian educational experience and the vocation of the intercultural religious educator.


agency thereof, nor any of their employees, makes any warranty, expressed or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness, of any information, apparatus, product, or process disclosed, or represents that its use would not infringe privately owned rights. References herein to any specific commercial product, process, or service by trade name, trade mark, manufacturer, or otherwise, does not necessarily constitute or imply its endorsement, recommendation, or favoring by the U.S. Government or any agency thereof. The views and opinions of authors expressed herein do not necessarily state or reflect those of the U.S. Government or any agency thereof. SUMMARY The purpose of ring compression testing is to generate data to support the development of the technical basis for extended storage and transportation of high-burnup fuel. Argonne National Laboratory developed the methodology of using ring compression tests (RCTs) for radial-hydride-treated (RHT) cladding to generate data for the Nuclear Regulatory Commission (NRC) on the behavior of high-burnup Zircaloy-4 (Zry-4) and ZIRLO™ cladding. The RHT/RCT methodology is an established test protocol accepted by NRC for generating data to support the technical basis for licensing storage and transportation casks with high-burnup fuel. In July 2011, Phase I testing for DOE on high-burnup M5 ® cladding was initiated under the ANL FY11 Work Package Transportation; Phase I testing for DOE on high-burnup M5 ® cladding continued into fiscal year 2012 under the ANL FY12 Work Package Engineering Materials Experimental. This report highlights the results of completed Phase I testing of high-burnup M5 ® cladding and the revised three-year test plan, which is included in the Appendix. Relative to lower-burnup fuel, high-burnup (≥45 GWd/MTU) used fuel rods are characterized by increased: decay heat following reactor discharge, internal gas pressure, cladding corrosion-layer thickness, and cladding hydrogen content. Under pool-storage conditions following reactor discharge, hydrogen in fuel cladding will be in the form of hydrides precipitated in the circumferential direction. Circumferential hydrides, in combination with irradiation-induced hardening, decrease cladding ductility in response to axial and hoop loads, but high-burnup cladding still retains a low level of ductility. At elevated temperatures (≤400°C) during drying-transfer operations and the early stage of dry-cask storage, the internal gas pressure and cladding hoop stress increase, as some of the hydrogen goes into solution (e.g., about 200 wppm at 400°C). During cooling under tensile hoop stress, some of the dissolved hydrogen will re-precipitate in the radial direction …


A phase-transfer catalyst for controlled of oxidizing reaction has a chemical formula: QmHnXMpO4+3 or QmMO3(L). It is not soluble to reaction mediumd but can become the active substance soluble in reaction medium under the action of one reactant to further act on anothe reactant for selective reaction. When one of the reactants is consumed off, the catalyst can restore its initial structure and be educed out for cyclic use.


In this paper we review present theories relating to the formation of the earth's radiation belts and consider prospects for future development of these theories. The first part is devoted to the discussion of the possibility of particle injection into the zone of trapped radiation when the drift orbits of particles are perturbed during geomagnetic storms. In the second part we show that the experimental data on particle diffusion in the belts are generally in agreement with the concept of sudden impulses. The third is an analysis of the problem of proton and electron leakage due to ionization deceleration and cyclotron instability.


To investigate the effects of PGE1 on the quantity and activity of polymorphonuclear leukoytes(PMN), the level of endothelin(ET), and lipid peroxidation during human myocardial ischemia-reperfusion injury(IRI). 36 cases of acute myocardial infarction(AMI) were divided into two groups by random,treatment group(n=18) and control group(n=18).The treated group was given by venoclysis of PGE1, nitroglycerin and urokinase, while the control group was given nitroglycrin and urokinase only.The above parameters in peripheral venous blood were determined before and after reperfusion. The PMN activity, ET level and degree of lipid peroxidation were markedly increased during acute myocardial infarction stage. Moreover,these changes were further enhanced during reperfusion stage.However,these changes were obviously reversed following the administration of PGE1. PGE1 can inhibit PMN activity,reduce lipid peroxidation degree and ET level, showing a significant protection on human IRI.


EPSRC; EP/R513039/1 Abstract Herein, a novel approach to conduct peer‐to‐peer energy auctions for electric vehicles (EVs) to benefit both buyers and sellers is presented. It considers a scenario where households can sell their surplus solar energy to visiting EVs that make use of the households' vacant charge points during the day. The aim of the energy trading is to maximise the amount of charge EVs receive from the solar energy, and increase the revenue for sellers. The novel Closest EnergyMatching (CEM) double auctionmechanism is proposed and it is comparedwith four other mechanisms. CEMallows the auction to take into account current energy requests as well as the potential future demand without requiring additional information. Anovel algorithm,MARMES (MAtrix Ranking forMaximisingElement Selection), is also presented to solve the optimisation problem that forms the basis of the CEM mechanism. The CEM mechanism on average results in 21.5% more solar energy used, lower cost to the consumer, a 24.9% increase in profits for sellers and a 71.4% reduction in required grid energy compared with the traditional double auction mechanism.


Seven thousand five hundred current periodical titles are housed in the Current Periodicals Department (CPD) of the Sterling C. Evans Library at Texas A&M University. Before 1987 a door guard was posted at the CPD exit to prevent users from leaving the room with periodical issues. When the room was remodeled, security precautions were rescinded for the collection, and users were permitted to take current issues from the CPD proper to read in other locations in the library. A cost analysis is presented of the decision to allow use of current periodicals outside of the CPD. The cost of two alternative security measures is compared to the cost of reshelving, searching, binding and ordering lost and missing issues. Results indicate that the decision to discontinue security in the CPD was a valid one.


BACKGROUND
Rupture of papillary muscle generally happens during acute myocardial infarction and is the cause of acute mitral regurgitation, pulmonary oedema, so it should be promptly recognized and managed.

CASE REPORT
A patient, 52 year-old, was admitted to the Thoracic Department with fever, general weakness, dyspnea and cough as a case of suspected pneumonia. Two days before the admission he was treated with antibiotics. At thoracic ward, his clinical status got serious and he transferred to Intensive Care Unit (ICU) as pulmonary oedema. At the time of admission to ICU the patient was seriously ill with tachycardia, tachydyspnea, orthopnea and cyanosis image. Auscultatory, he showed pulmonal stasis at both sides and a tachyarrhythmic action, with a systolic murmur 5/6 grade above the mitral valve. Echocardiography showed grave mitral regurgitation with prolapsus of posterior leaflet with suspected chordal rupture. At coronarography no significant lesions of coronary arteries were found. After hemodynamic stabilization the patient was operated. During the operation, Transesophageal echocardiography (TEE) examination showed a rupture of the head of the posteromedial papillary muscle. He was surgically treated with atypical quadrantectomy of posterior leaflet with homologous pericardial patch anuloplasty.

CONCLUSION
The recognition of acute mitral regurgitation caused by the papillary muscle rupture and prompt surgical treatment is of vital interest for the survival of patients.


The article presents information on the formation Botanical Garden at Pyatigorsk Pharmaceutical Insti-tute, the history of its formation, the current status of the collection. Indicated perspective directions of develop-ment the Botanical Garden as a scientific and cultural center of Pyatigorsk.


This article reports the development and initial validation of a multidimensional measure of employability based on the theoretical model of Lo Presti and Pluviano (2016). Four different studies were designed and implemented. Study 1 was a qualitative study that involved a group of 15 labour market experts and aimed at developing the items pool. In Study 2, an exploratory factor analysis of 526 employees was carried out to examine the structure of the employability measure as previously obtained. Study 3 aimed at verifying the employability measure that had emerged from Study 2 through confirmatory factor analysis of 699 employees, resulting in a 28-item shortened version encompassing the original four employability dimensions. Finally, in Study 4, concurrent and predictive validity of the definitive version of the employability measure were tested on a sample of 712 employees. Implications for vocational guidance and human resource management, as well as future employability research, are discussed.


Today, the cultural variety show market is faced with development impediment such as homogeneity and fatigue, but Everlasting Classics is still in its infancy and has realized phenomenal communication. Combining with the characteristics of the new era context, this paper makes a systematic text analysis on The Everlasting Classics, and explores the innovative expression of poems and even traditional culture in the new era as follows: The multidimensional innovative program format, the content expression of the times, and the shared transmission mechanism. We hope to provide new ideas and experiences for the development of subsequent cultural variety shows. Keywords—Cultural variety shows; Everlasting Classics; Traditional culture; Era innovation


In reinforced concrete structures the surface layer has an important role to prevent external attacks which can make causes for corrosion of reinforcing bars. For realizing dense and non-porous concrete on unformed surfaces a surface tamping vibrator has been developed and applied in practical construction procedures. Effects of the equipment has also been verified by some experimental works with checking a ratio of flexunal strength of specimen between with and without tamping procedures. According to the practical and experimental results standard usages of the surface tamping vibrator is proposed for surface finishing to enhance durability of concrete structures.