Part-time teachers are an important part of the teaching staff in non-governmental institutions of high learning.This paper analyzes the reasons of non-governmental institutions of high learning employing the part-time teachers.From the angles of teaching and management,this paper explores the problems existing in non-governmental institutions of high learning.Meanwhile,the author also proposes several countermeasures to strengthen the management of part-time teachers.Therefore,this paper is significant to sustainable development of non-governmental higher education.


ABSTRACT The introduction of innovation to a school doesn't just happen. Often it is the work of an interested and dedicated teacher. Such teachers are often frustrated in their efforts to change the curriculum because they lack both the leadership skills necessary for substantial change and an understanding of how innovation effects and spreads in an organization. School principals, in their position as curriculum leaders, should play a crucial role in bringing innovation to the classroom. Many, however, play an encouraging but less active role, supporting teachers' efforts to change the curriculum. While this type of leadership has been sufficient in the past, the introduction of computer technology as an integral part of the instructional program requires active leadership because of its multifaceted nature and intense budgetary requirements. This paper suggests a model of school administration wherein already overburdened school administrators can share leadership in a meaningful way with interested t...


OBJECTIVE: The contemporary obstetric population has evolved since Friedman's landmark studies. Evidence suggests that Chinese multiparous women have shorter labor progression. The goal of this study is to evaluate the lengths of first and second stage of labor among Chinese women. METHODS: We conducted a retrospective cohort study of term, singleton, vertex, laboring Chinese women from January 4, 2014, to August 13, 2014. We excluded patients with chorioamnionitis, fetal demise, and a trial of labor after cesarean delivery. Cervical dilatation was recorded from admission to delivery. RESULTS: This study included 208 patients. In nulliparous women, the mean maternal age was 26.1±3.6 years and neonatal birth weight was 3,192.3±348.8 g. The mean cervical dilatation on admission was 4.3±1.6 cm, and the time to full dilatation was 6.8±3.9 hours. The mean second stage was 1.2±0.8 hours. In multiparous women, the mean maternal age was 29.8±4.6 years and neonatal birth weight was 3,327.2±389.2 g. The mean cervical dilatation was 4.9±1.9 cm on admission, and the time to full dilatation was 3.2±2.7 hours. The mean second stage was 0.3±0.4 hours. CONCLUSION: In comparison with Friedman's nulliparous patients, our primigravid patients had a significantly faster first stage of labor (P<.001) and second stage (P=.006). In comparison with Friedman's multiparous patients, our multiparous patients had a considerably shorter first stage of labor (P<.001). Preliminary findings suggest standard management of labor may not apply in this population. Ethnic specific labor progression should be explored further.


An enumeration formula for counting the number of partitions of an integer 71 > 1 hewing parts in <U'ithrncLic progression of common difference two is derived in terms of the number of divisors of 71. As a consequence, a formula is obtained giving the number of Pythagorean triples in which 71 occurs as one of the base lengths in terms of the number of odd and even divisors of 712 .


Obesity is a serious problem, both in the United States and around the world. Although there are many factors that lead to becoming overweight, it is important to study what role the media may play. The purpose of this research is to examine how television use impacts nutritional views and knowledge, which in turn predict unhealthy food consumption. To do this, a survey was conducted that included measures related to television use, fatalistic views toward eating healthy, nutritional knowledge, and unhealthy food consumption. Based on mediation analysis, fatalistic views and nutritional knowledge partially mediate the relationship between television use and unhealthy food consumption. This implies that by inundating consumers of television with advertisements for unhealthy foods, entertainment programs with poor nutritional messages, and news programming with conflicting accounts of proper nutrition, the media are helping to create individuals who have a poor understanding of nutrition and adopt fatalistic views of eating healthy, which together relate to having a poor diet.


Abstract The incomplete gamma function was used to generate lactation curves for a large sample of Holstein records from the Northeast Dairy Herd Improvement Association files. Curves were fitted by linear regression on the logarithmic transformation of the incomplete gamma function. Effects of month of freshening, days open, and intra- and interherd variability in cumulative yield were determined separately by linear regression for first, second, and later lactations for each parameter of the model. These predictions were used to extend partial records of milk production to 305-day equivalent. Predicted effects of parity number and season of freshening on incomplete gamma parameters b and c were used to specify shape of the lactation curve for partial records. Since most variation in lactation curves for high and low producing cows was due to variation in the equation multiplier, this parameter (A) was changed to shift the predicted curve closer to observations in the partial records. Predictions of 305-day cumulative yield from partial records by this technique had smaller root mean squares (356 to 586 kg) than the test interval method with extension factors (396 to 751 kg).


Atypical twinning highlights that complex mechanisms responsible for twinning are not fully understood and may give further insight into the mechanisms involved. To assume that phenotypic difference is the result of dizygotic twinning would be erroneous and could have significant implications in the care and counseling provided to these patients.


The Psychodynamic Diagnostic Manual (PDM Task Force, 2006) is based on the assumption that an in-depth understanding of clients' underlying emotional, personality, and interpersonal patterns will facilitate their treatment. In this article I show how such an understanding can be achieved through multimethod psychological assessment, and how useful such information can be in long-term psychotherapy with high-achieving, successful clients who struggle with forming and maintaining intimate relationships. Such treatments are extremely difficult, because when these clients attach to their psychotherapists, many of them temporarily become more symptomatic. I illustrate these points with a detailed account of my long-term therapy with a resilient but highly traumatized young man. Repeated use of the Minnesota Multiphasic Personality Disorder–2 (MMPI–2; Butcher, Dahlstrom, Graham, Tellegen, & Kaemmer, 1989) and Rorschach with my client helped guide us in our work, and also helped create an important therapeutic "opening" into the underlying traumatic material. This and other experiences have convinced me that it is extremely useful for psychologists to have training in both assessment and psychotherapy.


Numerical simulations of coarse-resolution, idealized ocean basins under constant surface heat flux are analyzed to show that the interdecadal oscillations that emerge naturally in such configurations are driven by baroclinic instability of the mean state and damped by horizontal diffusion. When the surface heat fluxes are diagnosed from a spinup in which surface temperatures are strongly restored to apparent atmospheric temperatures, the most unstable regions diagnosed by large downgradient eddy heat fluxes are located in the basin northwest corner where the surface heat losses are largest. The long-wave limit of the baroclinic instability of idealized mean flows in a three-layer model with vertical shears as observed in the GCMs demonstrates that growth rates of order one cycle per year can be produced locally, large enough to amplify thermal anomalies in the face of lateral diffusion. The proposed instability mechanism that favors surface-intensified perturbations also explains the lack of oscillations if the restoring to a surface climatology is too strong. To assess whether this instability process of oceanic origin is robust enough to cause interdecadal variability of coupled ocean‐atmosphere models, a four-box ocean‐atmosphere model is constructed. Given the large heat capacity of the ocean as compared to the atmosphere, the dynamical system that governs the model evolution is reduced to only two degrees of freedom, the oceanic overturning thermohaline circulation and the interior north‐south temperature gradient. The authors show that, when the baroclinic instability growth rate exceeds the overall dissipation caused by turbulent eddy diffusion in the atmosphere and ocean and infrared back radiation, the dynamical system undergoes a Hopf bifurcation, and interdecadal oscillations emerge through a limit cycle.


This article aimed to reveal the teaching-learning process of how to read and write the Qur'an with the Al-Barqy method to Faculty of Teacher Training and Education students at Sriwjaya University. The research method used qualitative method. The data collection was takenfrom observation, interviews, and documentation. The respondents consisted of students and lecturers of Islamic Education. This research focusedon the learning process of how to read and write the Al-Qur'an using the Al-Barqy method? What are the advantages and disadvantages used in the Al-Barqy method? The information obtained was analyzed with interactive analysis through several components, namely data collection, data reduction, data presentation, and drawing conclusions. Then the data from the observation and documentation were adjusted. This teaching-learning process only emphasized on the ability to read and write the Qur'an in Faculty of Teacher Training and Education students at Sriwijaya University. The result of this research of the teaching-learning process to read and write Al-Qur'an with the al-barqy method made students learn the Qur'an quicker and easiercompared to other methods. This method used easier steps and a fun process. And there were several advantages, namely: Used a short period of time which was up to 8 hours and for adults was only up to 200 minutes to read the Qur'an,can be used for all ages both children and adults. While the drawbacks of this method include: This method was called the 8-hour method meaning that the learning time was relatively short and if it was for children's education then we must pay attention to their conditions both endurance and their memories, the understandings of hijaiyah letters was not very deep.


The ability to think critically is very important for students because one's ability to be able to succeed in his life is determined by, among others, his thinking skills, especially in the effort to solve life's problems that he faces. The purpose of this study is to test the theory of CTL (Constructivist Theories of Learning) by analyzing the first, The Effect of Reciprocal Teaching learning methods and Discussion methods on students' critical thinking skills. Second, the effect of learning independence on students' critical thinking skills. Third, the effect of the interaction between the Reciprocal Teaching Method and learning independence on students' Critical Thinking Skill. The method used in this study is an experimental method with a comparative approach. The design used is factorial. The subject of the research were all students of class X IPS3 and X IPS4 SMA Negeri 1 Sumber, as many as 72 students. The instrument used are consisted of tests of critical thinking skills and a learning independence questionnaire. Data was analyzed with the test of two-way ANOVA. Based on the analysis results obtained: (1) The learning methods affect students' critical thinking skills, with sig. value 0.008 < 0.050, (2) Learning independence has a significant effect on students' critical thinking skills, with sig value 0,000 < 0.050, (3) There was no interaction effect between the learning methods and learning independence on students' critical thinking skill, with sig value 0.432 > 0.050. Based on the results of the study it can be concluded that: (1) learning with the reciprocal teaching method is more effective in improving students' critical thinking skills compared to the discussion method, (2) There are differences in the influence of high, medium and low learning independence in influencing the critical thinking skills of students in the experimental class and control class, the value of students' critical thinking skills with high levels of learning independence is more effective when compared to students with moderate and low levels of learning independence, (3) the moderator variable is not strengthening and weakening the independent variable, meaning that Reciprocal teaching learning methods and learning independence both play an important role and provide a major contribution in supporting the development of students' critical thinking skills


This invention relates to a multi-item dry test paper including a base plate with more than two items of test paper blocks on it and identifying strips on zones between the blocks suitable for positioning of test strips or positioning test paper block to be tested by instrument testing. Identifying strips are set at the front of the first or the back of the laser test paper or both as the starting or ending marked strips with advantages of increasing qualified products and productivity and accurate measurement, easy to identify for eye colorimetry test avoiding mistaken match of test blocks related to the standard test blocks.


Surface erosion can exert a tremendous impact on natural resources and can cause serious economic losses because of blocked streams, degraded water quality, destroyed bridges and road rights-of-way, ruined spawning sites, lowered soil productivity, and property damage. Soil properties important to the evaluation of a site for its resistance to erosion include: particle size, permeability, water retention characteristics, compressibility, shear strength, void ratio or porosity, shrink-swell potential, liquid limit, and plasticity index. Soil erosion control techniques have the potential to reduce runoff and soil loss. Traditional stabilizers, such as lime cement, fly ash, and bituminous materials, etc., usually require a long curing time. Hence today polymer stabilizer is used extensively because of its stable chemical properties and shorter curing time. To evaluate the possibility of a sustainable erosion stabilization as alternative to the traditional concepts (e.g., marl), the role of polymer within the stabilization process is presented in this paper. Findings of numerous studies revealed that the addition of polymer to natural soils produced an improvement in their mechanical capacities and constructability's. For the mechanical capacities, enhancements in unconfined compressive strength, California bearing ratio, shear strength and, the strength of the stabilized soil is significantly increased both under wet and dry conditions. Moreover, it is cost and time effective compared with traditional methods. To further evaluate and confirm the sustainability and advantages of polymer use for erosion stabilization, projects undertaken in the Kingdom of Saudi Arabia having the objective of increasing the resistance of soils to wind and water erosion were further evaluated to identify the possibility of altering from the traditional erosion design into this more sustainable and economic solution.


This paper explores the univariate and geostatistical representation of roller integrated continuous compaction control data. Univariate statistical analysis shows how the selection of the evaluation area leads to asymmetry in the data distributions that is inconsistent with regression analysis and can lead to QA failure. Geostatistical analysis reveals the presence of anisotropy.


Today's industries play a major role to develop and create new innovation products in manufacturing domain. The aim of this project is to identify the hazards, assess the risk and its root cause and to develop a control measures so that the major and minor hazards can be controlled in the tyre manufacturing industry and the workers will be working in a hazard free and safety environment. Material handling is the biggest cause of reportable accident in rubber industry and also hit by moving objects, falling objects, Noise, Fire etc... This can be identified and controlled by using the technique called HIRARC .By using these techniques the risks can be identified and the best safety measures can be implemented in the industry


The strata-bound Cu–Fe–S mineralization of the Lower Proterozoic Dunphy Formation forms the largest known sediment-hosted copper deposit of the Labrador Trough. Occurring in three thin stratiform d...


Providing an approach to calculate a suitable panel width for the longwall mining method is considered considering both the technical and economic factors. Based on the investigations carried out, a technical-economic model is proposed to calculate a suitable panel width. The proposed model is a combination of the rock engineering system-based model and the technical relationships to estimate the expected actual face advance rate of the longwall panel and also the economic relationships to determine the operational costs. Applying the technical conditions to the presented model is conducted by the vulnerability index of the advancing operation, which considers the face advance rate as the main important factor that controls the operational costs of the longwall face. The performance evaluation of the presented model is possible by the recordable field data, which is one of its advantages. This process is carried out by a case study, and the results obtained indicate that the developed approach can provide an applicable tool to calculate a suitable panel width.


In this paper,we give the details of the proofs of the following three theorems(Cf.Science Record,Academia Sinica,New Ser.Vol.I,No.3,1957,pp.1—5).Theorem 1.Let F(x)be an irreducible integral valued polynomial of degree k withoutany fixed prime divisor.Let(?)where w is the least integer satisfying(?)Then there are infinitely many integers x such that F(x)is a product of at most n primes.Theorem 2.Let k be a positive integer.Let n be an integer satisfying(1)and(2).Then for sufficiently large x,there is always an integer between x and x+x~(1/k)which has at most n prime factors.Theorem 3.For sufficiently large xm≤x+x~(10/17),there exists always a number(i)in interval xm≤x+x~(10/17) xith at most 2 prime factors;(ii)in interval xm≤x+x~(20/49) with at most 3 prime factors;and(iii)in interval xm≤x+x~(1/100+2/9)with at most 103 prime factors.


The MOSFET equivalent circuit model parameters are determined by performing the refined extraction method using Z-parameter formulations for parasitics and Y-parameter ones for geometric layout, excellent correspondence is observed between measured and fitted data of Z-parameter equations and the extracted intrinsic parameters exhibit mostly frequency-independent behavior. The scaling rule to gate width is observed to be applied for the extracted intrinsic parameters within reasonable errors. These extraction results essentially demonstrate the validity of this method in the wide range of gate bias and layout.


This paper uses multi criteria decision making methods to measure the performance assessment in engineering educational institutions in the state of Madhya Pradesh, India. To cater the need of technical manpower, a very large number of private engineering colleges have been established in the state of Madhya Pradesh of central India within a short span. The diminishing quality made so many engineering colleges forced towards closure is a concern in the state today. Therefore, the need for performance assessment and ranking of these engineering institutions is predominant. For the proposed framework, Technique for Order Preference by Similarity to the Ideal Solution (TOPSIS) and Grey Relational Analysis methods are applied for performance assessment of 28 engineering educational institutions taking into account some selected criteria.


The 2014 National Seismic Hazard Maps for the conterminous United States incorporate additional uncertainty in fault slip-rate parameter that controls the earthquake-activity rates than was applied in previous versions of the hazard maps. This additional uncertainty is accounted for by new geodesyand geology-based slip-rate models for the Western United States. Models that were considered include an updated geologic model based on expert opinion and four combined inversion models informed by both geologic and geodetic input. The two block models considered indicate significantly higher slip rates than the expert opinion and the two fault-based combined inversion models. For the hazard maps, we apply 20 percent weight with equal weighting for the two fault-based models. Off-fault geodetic-based models were not considered in this version of the maps. Resulting changes to the hazard maps are generally less than 0.05 g (acceleration of gravity). Future research will improve the maps and interpret differences between the new models.


Introduction Distinct progress towards sutureless surgery followed the discovery of the adhesive properties of cyanoacrylates by a group of investigators in 1959. 1 A year later Nathan and co-workers 2 described the effectiveness of methyl 2-cyanoacrylate in the nonsuture closure of incisions in the aorta of dogs. Currently, the surgical potential of these adhesives is being defined. Encouraging reports include the nonsuture repair of blood vessels and bronchi, sutureless intestinal anastomosis, the treatment of mandibular fractures in dogs, the closure of skin incisions, and renal and hepatic hemostasis. 3-9 It is important to investigate fully both the advantages and disadvantages of any experimental product intended for humans. The purpose of this report is to present the results of injecting methyl 2-cyanoacrylate, supplied by the Borden Company as AD/here, into Swiss albino mice. The results indicate that methyl 2-cyanoacrylate is toxic to small laboratory animals. Methods Detailed accounts of the


The Dark Side of Langerhans Cells Several immune cell populations reside in the skin and are thought to provide a protective barrier against infections and to act as sentinels against malignant transformation. However, studies in mice that lack Langerhans cells, a subset of dendritic cells, have suggested that these cells may actually promote tumorigenesis. Using a mouse model of squamous cell carcinoma, Modi et al. (p. 104) now reveal how Langerhans cells may promote the transformation of skin epithelial cells. In response to the carcinogen 7,12-dimethylbenz[α]anthracene (DMBA), Langerhans cells increased their expression of the cytochrome P-450 enzyme CYP1B1, which can metabolize DMBA to the mutagenic DMBA-trans-3,4-diol. Thus, besides their functions in regulating the adaptive immune response, Langerhans cells may participate in the metabolism of environmental carcinogens. A specialized immune cell population in the skin promotes tumorigenesis by metabolizing environmental carcinogens. Polyaromatic hydrocarbons (PAHs) are prevalent, potent carcinogens, and 7,12-dimethylbenz[a]anthracene (DMBA) is a model PAH widely used to study tumorigenesis. Mice lacking Langerhans cells (LCs), a signatory epidermal dendritic cell (DC), are protected from cutaneous chemical carcinogenesis, independent of T cell immunity. Investigation of the underlying mechanism revealed that LC-deficient skin was relatively resistant to DMBA-induced DNA damage. LCs efficiently metabolized DMBA to DMBA-trans-3,4-diol, an intermediate proximal to oncogenic Hras mutation, and DMBA-treated LC-deficient skin contained significantly fewer Hras mutations. Moreover, DMBA-trans-3,4-diol application bypassed tumor resistance in LC-deficient mice. Additionally, the genotoxic impact of DMBA on human keratinocytes was significantly increased by prior incubation with human-derived LC. Thus, tissue-associated DC can enhance chemical carcinogenesis via PAH metabolism, highlighting the complex relation between immune cells and carcinogenesis.


The author reveals military education modernization problem in the modern conditions as major control facility of building, strengthening and developing the armed forces and perfecting the armys spiritual life.


To effectively engage demand-side and distributed energy resources (DERs) for dynamically maintaining the electric power balance, the challenges of controlling and coordinating building equipment and DERs on a large scale must be overcome. Although several control techniques have been proposed in the literature, a significant obstacle to applying these techniques in practice is having access to an effective testing platform. Performing tests at scale using real equipment is impractical, so simulation offers the only viable route to developmental testing at scales of practical interest. Existing power-grid testbeds are unable to model individual residential end-use devices for developing detailed control formulations for responsive loads and DERs. Furthermore, they cannot simulate the control and communications at subminute timescales. To address these issues, this paper presents a novel power-grid simulation testbed for transactive energy management systems. Detailed models of primary home appliances (e.g., heating and cooling systems, water heaters, photovoltaic panels, energy storage systems) are provided to simulate realistic load behaviors in response to environmental parameters and control commands. The proposed testbed incorporates software as it will be deployed, and enables deployable software to interact with various building equipment models for end-to-end performance evaluation at scale.


Agri-environment policies have become increasingly important in the Organization for Economic Co-operation and Development (OECD) in the European Union (EU) countries. Agro-environment support payments in Latvia until its accession to the EU were available in relatively limited amounts from the state budget and its funding from year 1998 until 2010 reached 2.5 million LVL3. After accession to the EU in 2004, support measures, including agri-environment support, are implemented in accordance with the Common Agricultural Policy (CAP). Main document for agro-environment support payment implementation was Rural Development Plan in 2004-2006 year period and Rural Development Programme in 2007-2013 year period. Main sources of funding European Agricultural Guidance and Guarantee Fund (EAGGF) and European Agricultural Fund for Rural Development (EAFRD). In Latvia during years 2004-2009 number of beneficiaries of EU funded agrienvironment payments has increased from 2267 up to 16000. In this period paid out were 107.9 million LVL in agro-environment payments in Latvia, which is an increase from 4.4 million LVL paid out in 2004 up to 24.6 million in 2009. Currently there are 11 various agro-environment support payments implemented in Latvia.


Abstract: The present research focuses on performance improvement of linear model-based predictive control scheme (LMBPCS) by using intelligent approaches. The intelligent model-based predictive control scheme (IMBPCS) is in fact proposed to solve the problems of LMBPCS, encountering a number of severe complex systems. The key idea of the paper presented here is to reorganize a member of LMBPCS, so-called linear model based generalized predictive control scheme (LGPCS) by realizing fuzzy-based approaches, as intelligence-based candidates. Takagi-Sugeno-Kang (TSK) fuzzybased approach is investigated, in this research, to present a novel scheme, titled TaSuKaG strategy in association with LGPCS, in order to deal with complex systems, which have unpredictable behaviors with respect to time. The proposed TaSuKaG strategy is extendable by increasing the number of subsystems, i.e., most of severe complex systems could appropriately be dealt with, correspondingly, if mathematical representations are available. To discuss the validity of the proposed TaSuKaG strategy, a nonlinear system, realized based upon a set of linear models, has been chosen to drive, under different set points. The results indicate that TaSuKaG strategy has better performance in comparison with LGPCS.


In the
distribution center, the way of order picking personnel to pick goods has two
kinds: single picking and batch picking. Based on the way of the single picking
and assumed warehouse model, in order to reduce the walking path of order
picking, the order picking problem is transformed into the traveling salesman
problem in this paper. Based on backtracking algorithm, the order picking path gets
optimized. Finally verifing the optimization method under the environment of VC++6.0,
order picking path in the warehouse model get optimized, and compared with the
traditional order picking walking paths. The results show that in small and
medium-sized warehouse, the optimization method proposed in this paper can
reduce order picking walking path and improve the work efficiency as well as
reduce the time cost.


We retrospectively studied HLA typing which had been performed since 1986. The results of HLA typing determined by the serological typing were compared with those determined by DNA typing using the modified PCR-RFLP method. With the serological method,HLA-A, B, C, typings were 100% feasible but HLA-DR, DQ typing were unfeasible in 20.9% of recipients for bone marrow transplantation all of which were definitively defined for HLA class II alleles by the PCR-RFLP method. Most of these serological "blank" antigens were DRS, DR6 and DR8 which could be easily detected by DNA typing. The PCR-RFLP method which is not influenced by lymphocyte viability, is essential for the practice of recipient-donor matching in bone marrow transplantation.


We describe a lithographic technique using atomic force microscopy (AFM) to expose commercially available photoresists in a controllable manner. In contrast to scanning tunneling microscopy lithography on photoresists, the AFM has the advantage of having better control of the contact force between the probe tip and sample and thus reduces the possibility of physical damage to the resist material during exposure. Using a metal coated cantilever, we have been able to create resist patterns at the nanometer-scale.


Aim – to analyze methodological approaches to the functional zoning of the territory of agro-businesses on a landscape-ecological basis in the steppe zone of Kazakhstan for the purposes of land management. Methods – monographic, settlement-constructive, grouping, graphic modeling. Results – relevant problems of greening the land use of the republic, which needs to update the design methodology for the use and protection of agricultural land, taking into account the criteria for environmental protection, are shown. Typical objects are selected – agribusinesses of the steppe landscape zone, in which studies were carried out. An analysis of the resources of this area is given, ecological stability of agricultural landscape, an important component of which is erosion processes, is determined. Maps have been developed that characterize landscape and ecological features of a given area and are the basis for territorial zoning: a landscape hypothesis map with identification of elementary natural territorial complexes, a map of ecological stability of the territory and a map of the functional zoning of the area. The principles of agri-relief planning are justified, including the unification of morphological structural units of the landscape into a single land types in terms of ecological state and expediency of using land types with implementation of appropriate measures for each ecological landscape group. An experimental project has been developed in which a territorial organization is made on the example of economic entities of agricultural specialization in the steppe zone on ecological landscape substance. Conclusions – the basis for development of land management projects for agricultural structures should be a scientifically based system of organizational and economic measures for reconstruction of land area of agricultural enterprises on a landscape basis, which implies the design of environmentally sustainable and costeffective forms of land management.


In the context of an increasing demand for data and computational services, the benefits of cloud computing are substantial. However, cloud computing capabilities (as currently provisioned) can prove limited when accessed through a single provider. Extending capabilities of clouds by using user owned and provisioned devices can address a number of challenges arising in the context of current cloud deployments – such as data centre power efficiency, availability and outage management and secure access. We present a mechanism of forming trustworthy P2P clouds where various end-users can join and exchange resources. We propose a trust model for managing the formation and use of such clouds where feedback aggregation is used for identifying the trust distribution. Using various experimental setups we evaluate the status of the cloud in the context of different malicious end-users.


It is difficult to predict the heating time and power consumption associated with the self-heating process of lithium-ion batteries at low temperatures. A temperature-rise model considering the dynamic changes in battery temperature and state of charge is thus proposed. When this model is combined with the ampere-hour integral method, the quantitative relationship among the discharge rate, heating time, and power consumption, during the constant-current discharge process in an internally self-heating battery, is realized. Results show that the temperature-rise model can accurately reflect actual changes in battery temperature. The results indicate that the discharge rate and the heating time present an exponential decreasing trend that is similar to the discharge rate and the power consumption. When a 2 C discharge rate is selected, the battery temperature can rise from −10 °C to 5 °C in 280 s. In this scenario, power consumption of the heating process does not exceed 15% of the rated capacity. As the discharge rate gradually reduced, the heating time and power consumption of the heating process increase slowly. When the discharge rate is 1 C, the heating time is more than 1080 s and the power consumption approaches 30% of the rated capacity. The effect of discharge rate on the heating time and power consumption during the heating process is significantly enhanced when it is less than 1 C.


Background: The present world literature widely discusses the use of Evidence-based Practice in selected groups of professionals in health sciences. The aim of the study: The aim of the study was to analyse the up-to-date world scientific literature on a broadly defined issue of modern methods of teaching health science students regarding the use of recent research results in everyday clinical practice, i.e. Evidence-based Practice. Material and methods: The analysis involved the world scientific literature indexed in the following databases: EMBASE, PROQUEST, PUBMED, and SCOPUS. The analysis comprised articles written in English between the years 2000 and 2013 (date of publication: between January 1st, 2000 and November 12th, 2013). A total of 1001 articles on the use of EBP in selected groups of professionals in health sciences were found, including 43 publications devoted to methods of teaching EBP to students; EMBASE - 1 item, Proquest - 11 items, PUBMED - 10 items, Scopus - 21 items. Since 5 publications were indexed in several databases at the same time, 38 publications were qualified for the analysis. Results: Publications devoted to teaching EBP to nurses were prevailing. A series of 6 specialist publications entitled Understanding research was found in the Practising Midwife. One of the publications was devoted to Physiotherapy students; none of the publications was devoted to Nutrition students. Conclusions: 1. There is a need to increase the awareness of academic teachers regarding the necessity for modern teaching of evidence-based everyday clinical practice to students. 2. The limitations in teaching students how to use research evidence in their professional practice are objective and they require system changes with reference to the clinical training of health science students.


The sesquicentennial of sugar production in Hawai'i is being observed in 1985 because Ladd & Go. initiated its sugar operation at Koloa, Kaua'i in 1835. Successors to the Ladd & Co. enterprise have continued to grow sugarcane on some of the same lands, and the cane has been milled in factories located near the same site as that of the first mill. While the Ladd operation is reckoned as the beginning of sugar production in Hawai'i, there are reports, most of them fragmentary, of other even earlier efforts. One report says, "Old residents speak of sugar and molasses of a coarse quality having been manufactured here in sufficient quantities for ordinary domestic consumption in 1828." Reports of the early attempts are scattered, most are documented poorly, if at all, there are inconsistencies among them, and there has never been a comprehensive summary of them. It is the purpose of this paper to review and compare the reports of sugar making in Hawai'i prior to 1835.


The transfer matrix method has been widely used to calculate wave propagation through the layered structures consisting entirely of either linear or nonlinear optical materials. In the present work, we develop the transfer matrix method for structures consisting of alternating layers of linear and nonlinear optical materials. The result is presented in a form that allows one to directly substitute the values of material constants, refractive index and absorption coefficient, into the expressions describing the second harmonic generation (SHG) field. The model is applied to the calculation of second harmonic (SH) field generated in nano-thin layers of transition metal dichalcogenides exfoliated on top of silicon oxide/silicon Fabry-Perot cavity. These structures are intensively studied both in view of their unique properties and perspective applications. A good agreement between experimental and numerical results can be achieved by small modification of optical constants, which may arise in an experiment d...


The minimum inhibitory concentration(MIC) and fractional inhibitory concentration(FIC) of Shuanghuanglian syrup combined with Penicillin G on Staphylococcus aureus were detected by the standards of NCCLS and combined chemosensitivity test to study the in vitro antibacterial activity of Shuanghuanglian syrup and penicillin G combination.The results showed that the MIC of Shuanghuanglian syrup and penicillin G on S.aureus were 46.88mg/mL(with dilution of 1∶32) and 0.25 U/mL,respectively.The FIC index of Shuanghuanglian syrup and penicillin G combination on S.aureus was 0.125.It indicated that the antibacterial action of Shuanghuanglian syrup combing with penicillin G against S.aureus presented synergistic effect.


Introduction: Selinexor is a novel, oral Selective Inhibitor of Nuclear Export (SINE) compound that blocks exportin 1 (XPO1). Selinexor treatment results in nuclear accumulation and activation of tumor suppressor proteins, inhibition of NF-kB, and translational suppression of several oncoprotein mRNAs (e.g., c-myc, cyclin D).Multiple myeloma (MM) remains incurable, and most patients (pts) eventually progress through standard drug classes of proteasome inhibitors (PIs), immunomodulatory drugs (IMiDs), anti-CD38 mAbs and others. The increased use of combinations in MM treatment, (PIs/IMiDs/mAbs), has led to a growing number of pts with penta-refractory MM (pts that have been treated with bortezomib (bort), carfilzomib (carfil), lenalidomide (len), pomalidomide (pom) and daratumumab (dara)). Active novel therapies with different mechanisms of actions are needed to address this unmet medical need. Part 1 of STORM enrolled pts with both quad- (bort, carfil, len, pom, treated MM) or penta-refractory MM and demonstrated an overall response rate (ORR) of 21% (Vogl et al, JCO 2018). Based on these findings, the Pivotal Part 2 of STORM was initiated, enrolling an additional cohort of 122 patients with penta-refractory MM.
 Methods: Pts with penta-refractory MM were treated with 80 mg selinexor plus 20 mg dexamethasone (Sd) twice weekly. Pts must have received an alkylator, bort, carfil, len, pom and dara, and had MM refractory to ≥1 PI, ≥1 IMiD, dara, a glucocorticoid, and their last therapy. Pts must have a total ANC ≥1000 mm3,platelets ≥50k/mm3 (or ≥75k if marrow plasma cells <50%), and creatinine clearance ≥20 mL/min. The primary endpoint was ORR. Secondary endpoints: duration of response (DOR), clinical benefit rate (CBR), progression free survival (PFS), and overall survival (OS). Efficacy was assessed by an Independent Review Committee (IRC) based on IMWG criteria. OS was also compared to a cohort of pts with PI, IMiD, dara refractory MM from the Flatiron Health Analytic Database (FHAD), (ref: ASH 2018 abs ID: 116493),who met all the inclusion criteria for STORM.
 Results: As of 1-Jun-2018, 122 pts (71 M/ 51 F) were enrolled in 38 sites (US and EU). Pt characteristics were [medians (range)]: age 65 yrs (40-85); 7 (3 - 18) prior treatment regimens, 6.6 yrs (<1 - 23.4) from initial MM diagnosis.65 pts (53%) had high risk cytogenetics, 86 pts (70%) had prior dara in combination, 102 pts (84%) had prior stem cell transplantation, 2 pts had prior CAR-T therapy. All pts enrolled with progressive disease (PD), 72% of pts had increases (3% - 792%) in MM markers from screening to C1D1 (median 11 days). Frequently reported Sd treatment related adverse events (AEs) included (all grades, grades 3/4): thrombocytopenia (67%, 53%), nausea (67%, 10%), fatigue (68%, 21%), anorexia (50%, 2%), anemia (46%, 28%), and weight loss (46%, 0%). Eight pts remain on study and 114 pts discontinued treatment (most commonly for PD). There were 4 deaths on treatment: sepsis, respiratory failure, pulmonary embolism, and an unrelated, unspecified cardiac event. IRC determined ORR (≥PR) was 26.2%, with 6.5% ≥ very good partial response, including 2 stringent complete responses (sCRs; MRD negative at 1:10-6 and at 1:10-4sensitivity). Both pts who relapsed after CAR-T achieved PRs. The CBR (≥minimal response, [MR]) was 39.3%, and 79% of pts achieved ≥stable disease (SD). Responses typically occurred within the first month. Medians: DOR 4.4 months (mo) (range <1 - 10 mo), PFS 3.7 mo, and OS 8.0 mo. Pts with ≥MR had significantly longer OS than pts with PD/NE (median not reached vs 1.9 mo, p=<0.0001). Compared to the FHAD cohort, STORM cohort had longer OS (Figure 1, HR 0.41, p=0.0001).
 Conclusions: Results of the pivotal STORM Part 2 in penta (PI, IMiD, dara)-refractory MM demonstrated that oral selinexor plus low-dose dexamethasone (Sd) was highly active with an ORR of 26.2%. Importantly, responses were rapid and deep with 2 patients achieving sCRs (both MRD negative) in these heavily pre-treated penta-refractory MM pts (median 7 prior regimens, 53% high risk). AEs are a function of dose/schedule/disease severity and can be managed with dose modifications and supportive care. No major organ toxicity was observed and AEs were typically transient and reversible. Sd is an all-oral, first in class mechanism with novel MOA and represents a potential therapeutic option to the growing number of pts with penta-refractory MM who have exhausted approved therapies.

 Chari: Novartis: Consultancy, Membership on an entity's Board of Directors or advisory committees, Research Funding; Adaptive Biotechnology: Membership on an entity's Board of Directors or advisory committees; The Binding Site: Consultancy; Seattle Genetics: Membership on an entity's Board of Directors or advisory committees; Array Biopharma: Research Funding; Celgene: Consultancy, Membership on an entity's Board of Directors or advisory committees, Research Funding; Amgen: Consultancy, Membership on an entity's Board of Directors or advisory committees, Research Funding; Pharmacyclics: Research Funding; Takeda: Consultancy, Membership on an entity's Board of Directors or advisory committees, Research Funding; Janssen: Consultancy, Membership on an entity's Board of Directors or advisory committees, Research Funding; Bristol Myers Squibb: Consultancy. Vogl:Karyopharm Therapeutics: Consultancy. Dimopoulos:Takeda: Honoraria; Bristol-Myers Squibb: Honoraria; Janssen: Honoraria; Amgen: Honoraria; Celgene: Honoraria. Nooka:GSK: Consultancy, Membership on an entity's Board of Directors or advisory committees; Janssen pharmaceuticals: Consultancy, Membership on an entity's Board of Directors or advisory committees; Adaptive technologies: Consultancy, Membership on an entity's Board of Directors or advisory committees; Takeda: Consultancy, Membership on an entity's Board of Directors or advisory committees; Celgene: Consultancy, Membership on an entity's Board of Directors or advisory committees; Amgen: Consultancy, Membership on an entity's Board of Directors or advisory committees; BMS: Consultancy, Membership on an entity's Board of Directors or advisory committees; Spectrum Pharmaceuticals: Consultancy, Membership on an entity's Board of Directors or advisory committees. Moreau:Amgen: Honoraria, Membership on an entity's Board of Directors or advisory committees; Janssen: Honoraria, Membership on an entity's Board of Directors or advisory committees; Celgene: Honoraria, Membership on an entity's Board of Directors or advisory committees; Abbvie: Honoraria, Membership on an entity's Board of Directors or advisory committees; Takeda: Honoraria, Membership on an entity's Board of Directors or advisory committees. Cole:University of Michigan: Employment; Cancer Support Community myeloma advisory board: Membership on an entity's Board of Directors or advisory committees. Dingli:Millennium Takeda: Research Funding; Alexion Pharmaceuticals, Inc.: Other: Participates in the International PNH Registry (for Mayo Clinic, Rochester) for Alexion Pharmaceuticals, Inc.; Alexion Pharmaceuticals, Inc.: Other: Participates in the International PNH Registry (for Mayo Clinic, Rochester) for Alexion Pharmaceuticals, Inc.; Millennium Takeda: Research Funding. Vij:Jazz Pharmaceuticals: Honoraria; Karyopharm: Honoraria; Janssen: Honoraria; Amgen: Honoraria; Takeda: Honoraria, Research Funding; Bristol Myer Squibb: Honoraria, Research Funding; Celgene: Honoraria, Research Funding. Raab:BMS: Consultancy, Honoraria, Research Funding; Novartis: Consultancy, Honoraria, Research Funding; Celgene: Consultancy, Honoraria; Amgen: Consultancy, Honoraria, Research Funding. Weisel:Amgen, BMS, Celgene, Janssen, and Takeda: Honoraria; Amgen, Celgene, Janssen, and Sanofi: Research Funding; Amgen, BMS, Celgene, Janssen, Juno, Sanofi, and Takeda: Consultancy, Membership on an entity's Board of Directors or advisory committees. Delforge:Celgene and Janssen: Research Funding; Amgen, Celgene, Janssen and Takeda: Consultancy. Stewart:Amgen Inc., BMS, Celgene, Takeda, Roche, Seattle Genetics, Janssen, Ono: Consultancy; Amgen Inc., Celgene, Roche, Seattle Genetics: Research Funding. Mohty:Amgen: Consultancy, Honoraria; Molmed: Consultancy; Sanofi: Consultancy, Honoraria, Research Funding, Speakers Bureau; Servier: Consultancy; Jazz Pharmaceuticals: Honoraria, Research Funding, Speakers Bureau; Janssen: Honoraria, Research Funding, Speakers Bureau; MaaT Pharma: Consultancy, Membership on an entity's Board of Directors or advisory committees; Celgene: Consultancy, Honoraria; Takeda: Honoraria, Speakers Bureau; Bristol Myers: Consultancy, Research Funding. Sylvain:Gilead: Other: scientific advisor board. Costa:Celgene: Honoraria, Research Funding; Abbvie: Research Funding; Karyopharm: Research Funding; Janssen: Research Funding; Amgen: Honoraria, Research Funding; Sanofi: Honoraria; BMS: Research Funding. Shah:Karyopharm Therapeutics: Employment. Picklesimer:Karyopharm Therapeutics: Employment. Saint-Martin:Karyopharm Therapeutics: Employment. Li:Karyopharm Therapeutics: Employment. Kauffman:Karyopharm Therapeutics: Employment, Equity Ownership, Membership on an entity's Board of Directors or advisory committees. Shacham:Karyopharm Therapeutics: Employment, Equity Ownership, Membership on an entity's Board of Directors or advisory committees. Richardson:Celgene: Membership on an entity's Board of Directors or advisory committees, Research Funding; Oncopeptides: Membership on an entity's Board of Directors or advisory committees; Takeda: Membership on an entity's Board of Directors or advisory committees, Research Funding; Jazz Pharmaceuticals: Membership on an entity's Board of Directors or advisory committees, Research Funding; Karyopharm: Membership on an entity's Board of Directors or advisory committees; BMS: Research Funding; Amgen: Membership on an entity's Board of Directors or advisory committees; Janssen: Membership on an entity's B


Implementation of the policy of developing western regions is of great benefit to tourism of West China If tourism of West China want to gain still greater success in a new wheel of development, we should make a serious study of marketing strategy planning-speed up developing integrated tourism companies,enhance developing tourism product,increase investment of promotion and establish comprehensive distribution systems.


The article attempts to revise the concept of 'cosmopolitan sociability', proposed by Nina Glick-Schiller for the field of migration research, from the interactional perspective. Cosmopolitan sociability characterizes such forms of integration of mobile people that do not refer to ethnicity or the country of origin; instead they are based on openness, free emotional sharing, and general human competencies available to everyone. However, the use of the concept by anthropologists and sociologists seems to neglect specific situational mechanisms of how cosmopolitan sociability is produced and reproduced in everyday interactions. We seek to fill this gap addressing theoretical resources of ethnomethodological membership categorization analysis, as well as interaction ritual theory. We propose to combine these approaches as complementary conceptual frameworks to analyze cosmopolitan sociability practices at the situational level. Ethnomethodological tradition helps to identify mutual definition and accounting of what is happening in specific here-and-now situations. This allows analyzing the stability created within the framework of cosmopolitan interactions, as well as the specific moral order that is reproduced within them. Moreover, ethnomethodological analysis helps to identify contexts where cosmopolitan sociability can or cannot arise. Interaction ritual theory, as developed by Randall Collins, characterizes situational solidarities and group symbols emerging and sustaining in everyday interactions. It is also able to trace the influence of the individuals' past experiences (previous chains of interactions) on their participation in situations of cosmopolitan sociability. The proposed approach is illustrated by the analysis of several examples of labor migrants' interactions in the Federal Migration Service.


Disposed between a first body to be pressed and a second body to be pressed disposed so as to face the first body to be pressed, is a pressing structure for applying pressure onto the first body to be pressed and the second body to be pressed, characterized by having: a first spring member having a center portion contacting the first body to be pressed, two extremity portions respectively contacting the second body to be pressed, and two arm portions respectively extending from said center portion toward different said extremity portions; and a second spring member having a center portion contacting the second body to be pressed, two extremity portions respectively contacting the first body to be pressed, and two arm portions respectively extending from said center portion toward different said extremity portions.


The paper introduces several important concepts of editing put forward in the study of the science of editing,namely,the subject and object,the medium between authors and readers,the cultural construction and the information intelligence. The author points out that scientific concepts of editing are the basis for building the theory of editing, and the author also presents scientific principles for establishing scientific concepts of editing which include the application of philosophy,unity between theory and proacice,criticism and inheritance,and unity between editing and the science of editing.


Christian alternative schools which had the unique educational philosophy and the theological background in educational circles unlike mission schools appeared 10 years ago. These schools were not established in standing for definite theological aspects but had theological tendencies which dominated their school education. It is not only an opportunity that we can diagnose where Korean Christian education is, but also a start to understand the characteristics of Christian alternative schools. In addition, it helps know what is the goals Christian alternative schools hope to accomplish. By looking into theological tendencies based on the origin of Korean Christian alternative education and making the theological tendencies which control Christian alternative schools clear, the aims of Christian alternative schools can be certain. For this, first of all we have to understand Christian alternative education correctly, set up its notion to limit the range of the arguments, and examine the relations of Christian education and theology. The typical theological education of Korean Christian alternative schools are Evangelism Christian education which dominated the early history of Christian schools, Liberalism Christian education which appeared in alternative social movement so as to suggest alternative values about public education, and Reformed Christian education headed for theological tradition. We cannot deny that there are these three educations in any Christian alternative school. Christian alternative schools which emphasize on alternatives in secular alternative schools are related to Christian education based on liberalism theology, and Christian schools pursuing the educational purposes are related to orthodox theological Christian education. However now severe problems Christian alternative schools are faced with are not theological identity's but secular value's. Common secular values in Christian alternative schools show competitive education from an entrance examination, successful myths made from non-biblical comprehension about Christian leaders, distortion of essential and methodical values in education, and international Christian alternative schooling on purpose of English characterized education for globalization. Definitely all of these are why we lack theological and philosophical reflections on Christian education. It is necessary that we consider merits and demerits of theological tendencies which dominated Christian alternative schools, organize the educational philosophy, and keep it strong.


The invention provides a method for forming a semiconductor structure. The method comprises following steps: providing a substrate, a first interlayer dielectric layer, and a first grating conducting layer which is arranged in the first interlayer dielectric layer; forming a second interlayer dielectric layer on the surface of the first grating conducting layer and the first interlayer dielectric layer of a device region and a peripheral region; forming an amorphous carbon layer covering the surface of the second interlayer dielectric layer; performing first sloped etching processing to the amorphous carbon layer to remove the amorphous carbon layer of the peripheral region; forming a photoresist layer having a first opening on the amorphous carbon layer surface after the first sloped etching processing; using the photoresist layer as a mask layer, etching the amorphous carbon layer and the second interlayer dielectric layer along the first opening, and forming contact holes in the second interlayer dielectric layer of the device region; forming conductive plugs which can stuff into the contact holes. According to the method, by means of removing the amorphous carbon layer in the peripheral region of the substrate, by-product generated from the reaction between etching gas and the amorphous carbon layer of the peripheral region is avoided, wherein the etching gas is generated from the process of contact hole etching; and therefore, the yield rate of semiconductor structures and chip output are increased.


Objective To develop the hospital information intelligent statistical analysis system,and collect mass data of every information system in hospital,so as to provide decision support for hospital leaders.Methods Taking advantage of business intelligence technology to integrate hospital business data and build the data center.Combining with the modern statistical analysis method,we set up a comprehensive query and analysis platform,and on this basis,carry on the in-depth data analysis and decision support,in order to make management work more simple and efficient.Results By integrating kinds of resources dominated by HIS database,such as medical information,materials management information,personnel management information,we build uniform reports analysis center to realize the seamless integration of information systems.This system could not only provide data analysis reference for medical workers,but also construct a performance evaluation system on this basis,further,offer support for these leaders.Conclusion Developing an intelligent statistical analysis platform of rapid,efficient,easy-to-use could quickly improve the management level of hospital informatization.


times above the normal levels. In contrast with folic acid, the level of B12 was decreased in more patients (24.4%) but there was still no correlation between B12 levels and the cognitive performance. The mean level of B12 vitamin was 355.3 25.6 pg/ml. In conclusion, it is debatable whether the increase of B12 levels in patients who have already been diagnosed a suffering from AD could have a significant effect on cognitive performance.


The global sea level rise has an effect on eco-environmental change by the inundation and erosion in the coastal area. Forecasting model on the change of morpho-ecological environments by the sea level change will give us information for coastal area management by predicting environmental changes of the up-coming future. This research aimed to foresee eco-environmental changes by the sea level rise in coastal area. Prediction model used SLAMM model developed to forecast coastal changes by IPCC scenario. The model predicted centennial environmental changes in the mouth of Han river and Nakdong river, Suncheon and Hampyeung bay as case areas. To sum up the research findings, in the estuary of the Han river, tidal flat was gradually disappeared from the year 2075, scrubmarsh and saltmarsh belts were developed. In the Nakdong River estuary, scrubmarsh was decreased from the year 2025, tidal flat was deposited from the year 2050, and also, the Gimhae plain was partially inundated, and wetlands were formed. In the Hampyeung bay, saltmarsh was deposited in the year 2025, tidal flat expanded until 2050 was partially submerged after that time. Tidal flat of Suncheon bay was disappeared by the inundation after 2025, and saltmarsh was developed in the embayment.


Focusing on the demands for recognition of Quebec, the article discusses to what extent the notions of political culture and/or common public culture allow for the constitution of a political community where the actors see their identities recognized and their citizenship rights are respected. The analysis suggests that ideas like constitutional patriotism, when completely dissociated from substantive identity symbols, represent a manifestation of alienation of the citizens civic consciousness.


The present invention provides a method of traffic policing, the method comprising: configuring a common token bucket configuration parameters to perform the same network traffic policy, establishing a corresponding relationship with the network segment address of the data token bucket operation, in accordance with the said operational data token bucket correspondence relation acquiring operating data token bucket to be carried by the packet Regulated address corresponding to the acquired and using the common parameters token bucket configuration packet to perform traffic policing. Further, the present invention also provides a traffic policing device includes a storage unit and execution unit. The present invention can improve the efficiency of the traffic regulation, reducing the impact on the data forwarding performance, and also to reduce memory footprint.


For British and American literature research,due to the influence of the different cultural consciousness will have different understanding,this paper mainly from the cross-cultural theory of the basic point of view,combined with cultural awareness in English and American literature study effect,pay attention to in literary works reflect the British and American culture in the basis of language ability more thorough understanding of the connotation of the literary works.


In this paper, we investigate the scheduling problem with multi-resource allocation in cloud computing environments. In contrast to existing work that focuses on flow-level scheduling, which treats flows in isolation, we consider dependency among subtasks of applications that imposes a partial order relationship in execution. We formulate the problem of Multi-Resource Partial-Ordered Task Scheduling (MR-POTS) to minimize the makespan. In the first stage, the proposed Dominant Resource Priority (DRP) algorithm decides the collection of subtasks for resource allocation by taking into account the partial order relationship and characteristics of subtasks. In the second stage, the proposed Maximum Utilization Allocation (MUA) algorithm partitions multiple resources among selected subtasks with the objective to maximize the overall utilization. Both theoretical analysis and experimental evaluation demonstrate the proposed algorithms can approximately achieve the minimal makespan with high resource utilization. Specifically, a reduction of 50% in makespan can be achieved compared with existing scheduling schemes.


Since the discovery of milbemycins by workers at Sankyo in 19741>2) there have been many reports of similar related structures3~9). These natural products all possess anthelmintic activity but generally have weaker ectoparasiticidal activity than the avermectins10). The major structural difference between these two classes of metabolites is the presence of a disaccharide substitution possessing a-stereochemistry on the C-13 position of the macrolide ring in the avermectins. There are manyreports in the literature of semi-synthetic modifications of milbemycinsto allow the introduction of substituents at the C-13 positionll ~ 13). Here we describe the discovery and structural elucidation of a novel series of milbemycins14), the first natural compounds discovered possessing C-13 substitution since the discovery of the avermectins.


Cysteine and lysine were given to rats by stomach tube either alone or before whole body irradiation and the tissue eosinophils were counted. Repeated daily administration of cysteine and lysine for a week caused a significant decrease in the eosinophil count of the skin, duodenum and colon. Short term amino acid treatment caused no changes in the tissue eosinophil count. Whole body irradiation alone and after amino acid pre-treatment also caused a significant decline in the tissue eosinophil count. This concurs with observations that long-term treatment with ACTH and cortisone lowers the number of tissue eosinophils (Wegelius and Teir 1958, Rasanen 1961). The principal extra-medullary amount of eosinophils of the organism is in the tissues. The significance of these cells for the organism is that they constitute one of its defensive and protective mechanisms (Rytomaa 1960). There seems to be a relationship between the number of tissue eosinophils and the radio-protective effect of cysteine and lysine established earlier (Holsti 1960).


as it pertained to Indigenous peoples. The roots of such a critical view go back, of course, a long way, at least to J. H. Hobson's radical journalism at the turn of the twentieth century, especially to his Imperialism: A Study (1902), which set the stage for the growth of the ferocious anti-imperial critiques of the twentieth century. Over the course of five brisk chapters, Morgan engages much historiography on the topic, although the omission of David Cannadine'sOrnamentalism: How the British Saw Their Empire (2002) is glaring, as is the failure to engage properly (although it is listed in the bibliography) with Carl Berger's long-standing and highly influential work on the topic of (English-) Canadian imperial identity, The Sense of Power: Studies in the Ideas of Canadian Imperialism, 1867– 1914 (2013). That said, Morgan has used the work of a number of other trailblazers who, in the 1970s and '80s, began to probe the empire's history in nontraditional ways—names such as Shula Marks and Stanley Trapido prominent among them—and in this way goes some distance in covering the philosophical spectrum evident in British imperial historiography as it pertains to her topic. The singular strength of the book, however, is Morgan's clear ability as a synthesizer, for she draws together an immense amount of historiography on the topic, distilling it into a coherent and digestible whole. She skillfully weaves together the various examples of what it meant to be "British" (though inexplicably ignoring Linda Colley's illuminating work on this question, Britons: Forging the Nation 1707–1837 [1992]) that cut across the widespread geographical locations and other indices of Britain's settler colonies. Whether it was the early commercial encounters between traders and the Indigenous peoples of Canada's west coast, or those of Christian missionaries and the Zulu and Xhosa of South Africa, Morgan explains what was both structural and nuanced about these relationships and their aftermath. This book is emblematic of the British imperial field as it stands today, most especially as the subject is researched and taught in colleges and universities. In this respect, Morgan has made a valuable contribution to the cyclical revivification of imperial history generally. Her style makes for compelling reading, and the volume shows evidence of perspicacious editing and appealing production values. In short, this is a recommended text, especially for students and general readers looking for a synthetic introduction to the rich area of how the British Empire peopled itself during the long nineteenth century.


Brands are not just a sign. Brands are not just elements that position products and companies. For many years, brands have been regarded as the link between products/companies and their customers. However, this view has dramatically changed inasmuch as brands are now considered partners of the relationships they establish with consumers. In this line, this working paper develops a holistic model on the basis of a relational perspective of brand equity.


Nowadays, with the advancement of technology, the majority of problems facing the real world can possibly be resolved. We are compelled to adapt our environment in order to live better due to the growing population of the planet. Therefore, land development is essential when taking into account our sense of community. We came up with the idea of a product that offers online land owners and developers a platform. We have developed a mobile application that has an interface that allows developers to get information about the lands that are offered in our app by providing the location as input. Pictures, measurements, and the owner's contact information are all included in the description of the land. By entering a place, owners can also see the details of the developers. Additional contractor information will be given. Map finds the quickest route to get the user to their destination.


Quinone diazides are a class of diazo compounds, having a planar six-membered ring system with diazo, carbonyl and al-kene groups in conjugation. Earlier it was used in optical, electronic, polymer materials etc. In the last few years, various rearrangements reactions and insertion reactions were explored by these diazo compounds via the formation of metallo-carbenoids. Recently, it has been used to incorporate phenol moieties to hydrocarbons or arene/heteroarenes systems via transition metal-catalyzed C-H bond activation. The reactions proceed via C-H bond insertion or migratory insertion of metal-carbenes. In many cases, the site-selectivities were obtained by the guidance of various directing groups (remova-ble or non-removable). At the same time, several asymmetric approaches were also studied to incorporate phenol deriv-atives to arenes/heteroarenes furnishing compounds showing axial chirality with high stereoselectivity. In this review, we will mainly focus on directed regioselective arylation with quinone diazides under transition metal catalysis through C-H bond activation.


Each summer from 1901 to 1918, and intermittently thereafter through 1965, Odawa and Ojibwe actors in Northern Ontario and Michigan took part in operatic Native language performances of Longfellow's Song of Hiawatha financed by area railroads and captured on silent film. While audiences and reviewers understood the pageants to validate the reality of Longfellow's representations of vanished noble savages and while Native actors performed this script for pay in lean times, a closer look at their offstage lives, their onstage improvisations, and especially their humor reveals that these were also Indians playing Indian for Indian reasons. In an era of assimilation policies that outlawed drumming, dancing, and ceremony in public, and on stages designed to render them absent as twentieth century Native people, the actors insinuated their presence in heavily ramified, if subtle, ways. Crucially, performances enabled them to embody and thereby maintain a musical and dance repertoire associated with peoplehood and power, that could be rekindled with greater sovereignty by subsequent generations.


Objective:To analyze the correlation between CT appearances and pathological findings at acute stage pulmonary candidiasis in rabbits.Methods: Twenty-four New Zealand rabbits were randomly divided into experimental group and control group.Rabbits in the experimental group were inoculated with Candida albicans via percutaneous trachea puncture and those in the control groups were injected with normal saline via the same way.Chest CT scans were performed every other day from the day the inoculations were completed.The scan results were controlled with the pathological findings.Results: Pulmonary candidiasis model were confirmed in 13 rabbits.The early CT appearance of pulmonary candidiasis was found from the second day to the tenth day after inoculation.We found consolidation in 10 cases,including 6 sublobe consolidation(intra-alveolar exudates) and 4 lobe or section consolidation(pulmonary infarct or hemorrhage).Ground-glass attenuation(hemorrhage or exudates) was found in 6 cases and often coincided with other CT signs.Nodules were found in 3 cases and often found surrounding the bronchovascular bundle(granulomatous inflammation).Conclusion: Consolidation is the major CT findings of primary pulmonary candidiasis at acute stage,followed by ground-glass attenuation and nodules.Various signs can occur simultaneously with no specificity.


In this article, we examine the existence of Hilfer fractional (HF) stochastic differential systems with nonlocal conditions and delay via almost sectorial operators. The major methods depend on the semigroup of operators method and the Mo¨nch fixed-point technique via the measure of noncompactness, and the fundamental theory of fractional calculus. Finally, to clarify our key points, we provide an application.


CO2, as a harmful gas, is produced by factories and industries. The best way to remove it is to use natural absorbents/adsorbents such as polysaccharides and lignin-based materials.


OF THE THESIS The Sigma-Lambda Transition Magnetic Moment by Priscilla Cushman Petersen Dissertation Director: Professor Thomas J. Devlin The Primakoff effect was utilized in a measurement of the IO-A transition magnetic moment at the Fermilab neutral hyperon facility. A beam containing A's with average momenta of 150 GeV/c passed through a target. A small fraction of them interacted with the Coulomb field of the target nuclei to produce a to which subsequently decayed via the process: IO + AY. A sample of 5 x 10 AY events were analyzed for 7 different targets. and yielded a total of 2028 ± 139 Coulomb-produced IO's. The total Primakoff cross sections for A on beryllium. tin. and lead were determined to be 0Be. 0.033 ± 0.022 mb, 0Sn· 3.28 ± 0.34 mb. and 0Pb 9.20 ± 0.81 mb. There is an additional 71 systematic uncertainty. The Primakoff formalism predicts ° « Za ~IA' where ~IA is the IO-A transition magnetic moment. A least-squares fit of the experimental cross sections to this functional form yielded I~IAI (1.59 ± 0.05 ± 0.05) nuclear magnetons. This corresponds to a IO lifetime of t • (0.76 ± 0.05 ± 0.05) x 10' seconds or a radiative width of r • (8.6 ± 0.6 ± 0.6) keY. where the uncertainties are statistical and systematic. respectively. An additional uncertainty due to • approximations in the Primakoff formalism applies to these derived quantities: <51 on t and r. and <2.51 on I~IAI.


Congenital anomalies are major contributors to perinatal morbidity and mortality. They also cause emotional upset and social stigma to parents with affected children. Prenatal screening for these anomalies, especially those affecting the musculoskeletal system, is very essential in the primary prevention of disability and reducing perinatal mortality and morbidity osteogenesis imperfecta, thanatophoric dysplasia, achondroplasia, unilateral club foot and bilateral hypoplasia of both ulna and radius. A case each of bilateral club feet, unilateral absence of the entire upper limb, polydactyly of the fingers and 3 cases of spina bifida. Figures 1 and 2: 2D and 3D images of a fetus with Thanatophoric dysplasia at 32wks GA


Understanding of language is closely related to mathematical reasoning, because language has function as a means of communication to convey ideas or ideas to others. Submission of mathematical ideas delivered by students will show how far the level of student understading of the mathematical concepts they have. This research is a qualitative research with a descriptive approach which aims to describe the obstacles faced by students when using language on mathematical reasoning. Data obtained from observations, interviews, questionnaires, and documentations. Based on the results of the analysis conducted, it can be seen that constraints faced by students when using language on mathematical reasoning are feelings of shame and inferiority, difficulty understanding the sentence, and lack of vocabulary students have.


The so-called arbitrary decomposition of a given Mueller matrix into a convex sum of nondepolarizing constituents provides a general framework for parallel decompositions of polarimetric interactions. Even though arbitrary decomposition can be performed through an infinite number of sets of components, the nature of such components is subject to certain restrictions which limit the interpretation of the Mueller matrix in terms of simple configurations. In this communication, a new approach based on the addition of some portion of a perfect depolarizer before the parallel decomposition is introduced, leading to a set of three components which depend, respectively, on the first column, the first row, and the remaining 3 × 3 submatrix of the original Mueller matrix, so that those components inherit, in a decoupled manner, the polarizance vector, the diattenuation vector, and the combined complementary polarimetric information on depolarization and retardance.


In temperate countries, the seed of winter cereals must be planted before the end of winter in order to fruit within 12 months of sowing. By contrast, spring cereals, which generally can not survive the winter cold, flower soon after a spring sowing. The very notion of vernalization originated from this early agricultural experience. Systematic research was undertaken on this subject as early as 1857, by Klippart (128). He showed that among the various climatic factors of winter, the determining factor is the cold temperature to which the young plants are subjected for a few weeks ; this makes the winter cereals capable of flowering soon after the return of a warmer temperature. This notion was extended to other plants by von Seelhorst in 1898 (237) and much more extensively by Gassner in 1918 (89 ) , who showed the great variety of "cold requirements" (measured by minimal chilling time) displayed by numerous species known as "biennials" or "winter annuals" as opposed to "spring plants" or "summer annuals" which have no significant chilling requirement for flowering. Gassner also showed that in winter cereals the early swollen germinating seed is already sensitive to the specific cold effect. Finally, in 1928, Lysenko ( 155) established that slight imbibition (e.g., 50 parts water to 100 parts dry matter) makes the cereal seed susceptible to this action of cold without inducing the excessive germination that could prevent use of a sowing machine. It was Lysenko who gave a name to the phenomenon. As spring cereals are called J arovoe in Russian ( from "Jar"; formerly fire, or the god of spring) , he called the process which makes a winter cereal behave like a spring cereal "Jarovization," and translated the word in his own English, French, and German translations into "vernalization" (Latin vernum meaning spring) . Some French authors use the word "printanisa· tion" but vernalization is most commonly used. In the next 20 years, a tre mendous number of studies were undertaken on vernalization, mostly by agronomists, to quantitize the data on the process in cereals and in numerous other cultivated plants, in order to facilitate growing a crop following late sowing. From their study of vernalization, Lysenko and his followers built their famous phasic theory of the stadial development of plants (156, 157) and


The paper gives a short overview of ox/nitride gate stack prepared by rapid thermal chemical vapor deposition (RTCVD) for sub-quarter-micron CMOS process. The main portion is focused on the dissimilar characteristics of different interfacial oxide in ox/nitride gate stack. Post deposition annealing is also investigated including NH/sub 3/ and N/sub 2/O treatment. Excellent improvements are available including lower gate leakage current, comparable driving current, suitable interface density of states and stable gate dielectric reliability.


This paper presents a CMOS MEMS-based thermoelectric energy generator (TEG) device with an efficient heat dissipation path. For present CMOS MEMS-based thermoelectric generator devices, the output performance is greatly limited by the high thermal-contact resistance in the system. For the device proposed in the work, the silicon substrate is etched into two comb-shaped blocks thermally isolated from each other, which form the hot and cold sides. Thin-film-based thermal legs are densely located between the two blocks along the winding split line. Low internal thermal-contact resistance is achieved with the symmetrical thermal structure. When the TEG device is embedded between the heat source and heat sink, the heat loss can be well controlled with flat thermal-contact pads of the device. For a full device with 900 n/p-polysilicon thermocouples, the measured open-circuit voltage reaches as high as 146 mV K−1, and the power factor reaches almost five times higher value compared to the previously reported results. A test system integrated with a single device presents an open-circuit voltage of 110 mV K−1 when forcibly cooled by a Peltier cooler, or 26 mV K−1 when cooled by ambient air.


Introduction Many hydrous phases should exist in the subduction zone, and serpentine and chlorite should be important hydrous phases in the hydrous peridotite layer of the descending slab. We have already studied the dehydration of antigorite, which is one of the polymorph of serpentine, by time resolved X-ray diffraction method to determine the stability region and the dehydration kinetics of antigorite [1]. In this study, we adopted the same experimental method (time-resolved dehydration experiment) to chlorite to determine the stability region and the dehydration kinetics of chlorite, because chlorite is another important hydrous phase in the subducting slab.


The minimum-mean-square-error (MMSE) detection is advantageous in its low-complexity while suffering from severe performance degradation. The post-processing signal-to-interference-and-noise ratio (SINR) distribution of MMSE detector, however, shows the potential of high reliability in the high-SINR detected symbols. We propose a low-complexity multiple-input multiple-output (MIMO) detection scheme by exploiting the MMSE detector concatenated with the sphere decoder (SD), where the MMSE detected symbols above the SINR thresholds are retained as the final decisions and the remaining lower-SINR symbols are to be detected by the SD. By retaining the high-SINR symbols detected in the MMSE, the search space can be significantly reduced without incurring much extra error rate. Simulation results demonstrate that the proposed MMSE-SD detection scheme performs near-optimal performance at much lower computational complexities compared to SD algorithm.


As most of Micro Nuclear Reactor(MNR) projects are currently carrying out conceptual or basic designs, however their socio-economics and business models are very uncertain. They need not only to overcome technical and licensing risks but also find sufficient markets. On the other hand, business modelling is a systematic process to explore the external opportunities(O) and threats(T) for finding potential markets and business products, and examine internal strength(S) and weakness(W) for capturing the markets with the competitive traits of the products. Against the backdrop, this study is to develop an analytical framework of business modelling to estimate socioeconomics for the commercial application of micro nuclear reactors (MNRs) in the 2030s onwards. Chapter 2 explores potential markets for the MNRs. Chapter 3 and 4 examine competitive traits and business risks respectively. Chapter 5 explains how to develop analytical frameworks to estimate socio-economics of MNR businesses to capture the potential markets. Chapter 6 provides conclusions while summarizing research results and suggesting further studies.


Acute intermittent porphyria (AIP) is an autosomal dominant metabolic disorder caused by deficiency of porphobilinogen deaminase; an enzyme involved in synthesis of heme. We reported a case of 20 year old female patient presented with abdominal pain, vomiting, seizures and altered sensorium. She was diagnosed as a case of AIP in porphyric crisis with hyponatremia due to syndrome of inappropriate antidiuretic hormone secretion (SIADH) and was managed with dextrose, hypertonic saline and other supportive measures. Early diagnosis and treatment increases chances of better outcome. Introduction Acute intermittent porphyria is an autosomal dominant hepatic porphyria, resulting from deficiency of an enzyme, porphobilinogen deaminase. This enzyme is involved in the heme synthesis pathway. This is the second most common porphyria with an estimated prevalence of approximately 5 per 100,000 people. [1] In AIP, the porphyrin precursors, porphobilinogen and amino-levulinic acid (ALA), accumulate. The patient may present with abdominal pain or with neuropsychiatric manifestations. Diagnosis is confirmed with urine (PBG) porphobilinogen test. [2] Treatment involves removal of precipitating factor, administration of heme arginate, dextrose and symptomatic treatment. Delay in diagnosis and thus treatment can result in increased morbidity and mortality. We reported a case of acute intermittent porphyria presented as syndrome of inappropriate anti-diuretic hormone secretion (SIADH). Case History A 20 year old female patient presented to emergency with history of pain abdomen which was severe and colicky associated with nausea and vomiting. It was followed by history of seizure and altered sensorium. Patient got admitted to a www.jmscr.igmpublication.org Impact Factor (SJIF): 6.379 Index Copernicus Value: 71.58 ISSN (e)-2347-176x ISSN (p) 2455-0450 DOI: https://dx.doi.org/10.18535/jmscr/v6i2.34


Darwin's theory of evolution argued that the human race evolved from the same original cellas all other animals. Biological principles such as randomness, adaption and natural selection led to the evolution of different species including the human species. Based on this evolutionary sameness, DonaldR. Griffin (1915-2003) challenged the behaviourist claim that animal communication is characterized asmerely groans of pain. This paper argues that (1) all animals are embedded in a social system. (2) However,that does not mean that all animals are social animals. (3) That the human social ontology remains to beunique due to a gene-cultural co-evolution.


The role of vaginal cytology screening in preventing invasive carcinoma of the cervix was investigated in Cali, Colombia. The history of previous participation in screening programs was obtained from 204 patients with invasive carcinoma and from 2 sets of age‐matched controls: one from the same health center and one for the same neighborhood of the patient. Our results show that the risk of developing invasive carcinoma is at least 10 times greater in non‐screened than in screened women.


Overexpression of the catalytic subunit of telomerase (hTERT) immortalizes healthy human endothelial cells (EC) but its effect on senescence in pathological conditions is unknown. Our objective was to investigate whether hTERT overexpression would prevent senescence in EC isolated from patients with coronary artery disease (CAD). EC isolated from discarded internal mammary arteries of 11 patients undergoing CABG were infected or not with a lentivirus expressing hTERT and cultured in vitro. We quantified senescence by cytochemical detection of senescence‐associated b‐galactosidase, hTERT activity by real‐time TRAPassay, telomere length by Southern blotting, mRNA levels (p21 and ATM, a DNA damage response protein) by qPCR and oxidative stress by immunostaining of lipid peroxidation (HNE). Compared to control EC, lentiviral infection increased hTERT activity (p<0.05), elongated telomeres (p<0.05), decreased ATM and p21 mRNA levels (p<0.05), increased EC replicative potential (p<0.05) but only delayed the onset of senescence (p<0.05). HNE levels increased in both groups, with time (p<0.05). In conclusion, since no immortalization was observed, we hypothesize that hTERT overexpression delays replicative senescence but cannot bypass stress‐induced senescence associated with CAD.


The stem cell (SC), by definition, is undifferentiated and has the ability of self-renewal. SCs are also able to differentiate into diverse cell lineages. In recent years, several studies have searching for the characterization of SCs in adult and extra-embryonic tissues that could guide to develop strategies for tissue regeneration and repair. Among these tissues the placenta is an important source of adult SCs, being a reservoir of mesenchymal SCs (MSCs). Several biological signals and the environment influence the differentiation of MSCs, although this phenomenon is not yet fully understood. The NEPH protein family, which includes NEPH1, NEPH2 and NEPH3, is a group of evolutionarily conserved adhesion molecules that may be involved in this MSCs differentiation. These proteins are part of the immunoglobulin superfamily (IgSF) and regulate the morphogenesis of different tissues. The role of NEPH orthologs have been extensively characterized in vertebrates, where they act in neural development, synapse formation and myoblasts fusion. Moreover, several studies have described the expression of NEPH1 and NEPH2 in several tissues, supporting the hypothesis that they might be involved in SCs differentiation. Thus, the objective of this study was to compare the expression of NEPH genes between undifferentiated and differentiated MSCs obtained from human placenta. The placental cells used is this study comprise a population of MSCs, being characterized by the typical fibroblastic morphology, expression of MSCs markers and ability to differentiate into adipocytes when cultured in an inductive medium. Real time RT-PCR analysis demonstrated that both undifferentiated MSCs and MSCs differentiated into adipocytes express NEPH1 and NEPH2 genes. However, the expression of NEPH1 gene was 75% higher in MSCs differentiated into adipocytes than in the undifferentiated cells. In summary, our results suggest that NEPH1 gene may play a role in the differentiation of MSCs into adipocytes.


The author praises Pennsylvania Gov. Ed Rendell's proposal to raise income taxes and disallow deductions for royalty and interest paid to related corporations that are headquartered in low- or no-corporate-tax states.


A Bluetooth low energy (BLE) beacon device and a BLE advertising method are provided. The BLE advertising method includes: enabling a broadcast action with different advertising packets simultaneously, wherein the advertising packets include connectable and unconnectable advertising packets; setting advertising time information of the advertising packets; setting advertising data and an advertising packet address code; and executing the broadcast action for the advertising packets in sequence according to the advertising time information and the type of each of the advertising packets.


PROBLEM TO BE SOLVED: To provide an ethylbenzene conversion method for converting ethylbenzene in a raw material containing an 8C aromatic hydrocarbon to benzene in a high conversion rate. SOLUTION: The ethylbenzene conversion method comprises bringing a mixed raw material of an 8C aromatic hydrocarbon containing ethylbenzene into contact with an acid type catalyst containing at least one metal selected from the metals of the groups VII and VIII in the presence of H 2 , to convert ethylbenzene to benzene. The raw material comprises an ethyltoluene-containing 9-10C aromatic hydrocarbon and the ethyltoluene is converted to toluene with the conversion of the ethylbenzene. COPYRIGHT: (C)2008,JPO&INPIT


A part of the excitation function of the /sup 232/Th(n,2n) reaction was determined by the foil activation method for neutron energies of 6.745, 6.938, 7.190, 7.448, 7.697, 7.944, 8.457, 8.975, 9.445, 9.934, and 10.450 MeV. Neutron flux density was measured using reactions /sup 238/U(n,f), /sup 56/Fe(n,p), and /sup 27/Al(n,..cap alpha..). Activity of the /sup 231/Th residual nuclei was determined by their low energy ..gamma.. transitions detected with a high purity Ge spectrometer. Results of this experiment are compared with renormalized literature data.


Optimization theory is a key technology for inverse problems of reconstruction in science, engineering and economy. Discrete tomography is a modern research field dealing with the reconstruction of finite objects in, e.g., VLSI chip design or medical imaging. In this paper, we use new optimization problems and methods to approximately resolve this NP-hard problem. Our new introductions base on interpretations, algorithms and learning methods coming from the theories of coding and optimal experimental design. Here, we combine optimization with exploiting geometrical-algebraical symmetries or, more generally, equivariances.


In a world of increasing urbanization and where climate change is a growing concern, data presents itself as way to measure the established efforts and forecast future needs and policies as Lisbon finds means to solve some of the major problems that come with being a large city such as air quality and pollution, waste management, mobility, and overall quality of life for its residents. As such, this project developed a dashboard in a BI visualization tool comprised of metrics and indicators based on a tailored framework from the city derived from pre-existing frameworks and conversations with Lisbon's city experts. The result is a prototypical dashboard that can be built upon in the future, once the city invests in a stronger ICT infrastructure that allows for the collection of data to support a project of this nature, something that, currently, is lacking.


The functioning of state police supervision authorities in the economy should be considered necessary, and the privatization of performing police supervision tasks would be undesirable. This is justified by numerous premises. Public authorities consider in their activities primarily the implementation of the public interest, expressed in the protection of police states and goods, while private entrepreneurs act to make a profit, so the implementation of public interest (including the protection of police goods) would become a secondary value for them. In addition, the exercise of police supervision by public authorities is associated with the possibility of using coercion, which is an important factor affecting the effective implementation of police supervision.


In the review the analysis of the modern data on a role of the central nervous system and a mental condition of the woman in realization of gestation process is presented. Changes in functions of nervous system in pregnancy, on the one hand, are caused by gestation itself, and directed to the organization of optimum conditions for development of fetus, and on the other hand are caused by influence of external physical and social factors upon woman during pregnancy. Representation of two various aspects of change in mental functions is put forward in pregnancy psychology ofpregnancy and psychology of pregnant women.


We review educational curricula and professional opportunities for students getting a degree in Naval Architecture and Marine Engineering (NAME) in Greece. The only university currently offering such a degree in Greece is the National Technical University of Athens (NTUA), and specifically its School of Naval Architecture and Marine Engineering. The School's graduates typically find employment in the shipping industry, and currently enjoy strong demand from prospective employers, almost zero unemployment, and the highest average salary of all NTUA engineering graduates. We take stock at the skills necessary to enter this segment of the labor market, the structure of the educational program, and ideas on how it may evolve in the future.


This paper analyzed the status of technology-humanities convergence. For this analysis, types of human's needs are classified based on Maslow's hierarchy need theory and keywords for patent analysis are extracted. Then, trends of the technology and humanities are analysed by time series and technology types by patent keyword analysis.


This paper describes the utilization of non-destructive imaging using 3D x-ray microscopy for package development and failure analysis. Four case studies are discussed to explain our methodology an...


The Times has fewer, but longer international stories than it did two decades ago, and the front page contains a higher proportion of international items.


Eukaryotic ribosome assembly is a complex process involving the equimolar accumulation of four RNA molecules and more than 70 different ribosomal proteins. In mammalian systems the assembly process has been shown to be regulated at both the transcriptional and translational levels (Hammond and Bowman, 1988). It has been suggested that expression of ribosomal protein genes in plants and other organisms is coordinately regulated (Gannt and Key, 1985). A number of plant ribosomal protein genes have been isolated, including cDNA clones encoding the small subunit proteins S11, S13, S14, S16, and S19 (Larkin et al., 1989; Gannt and Thompson, 1990; Lebrun and Freyssinet, 1991; Warskulat et al., 1991; Taylor et al., 1992; Joanin et al., 1993) and the large subunit proteins L3, L7, L17, and L27 ( E m et al., 1990; Stafstrom and Sussex, 1992; Taylor et al., 1992; Gao et al., 1993). In severa1 instances the expression levels of these genes have been shown to increase dramatically in actively dividing tissues compared with quiescent tissues (e.g. Stafstrom and Sussex, 1992). However, the factors controlling ribosomal protein gene expression and the roles of individual proteins wíthin the ribosome have not been characterized. A cDNA library was constructed from stolon tips of potato at an early stage of tuberization and was differentially screened as described by Taylor et al. (1992). The characterization of a clone (TUBL27) isolated by differential screening is described here (Table I). The cDNA clone of the potato L27 gene was analyzed by DNA sequencing. The insert was 612 bp long and contained an open reading frame of 138 amino acids preceded by a 25-bp leader sequence and followed by a 172-bp 3' sequence. Comparison of the deduced amino acid sequence of the TUBL27 open reading frame was carried out using the GAP program of the Genetics Computer Group. It revealed a 78% identity with the pea L27 sequence, enabling the identification of the potato clone. Typical of ribosomal proteins, the L27 protein of potato is composed of a high percentage of basic amino acids. RNA-blot analysis confirmed that TUBL2 7 was expressed in a pattem very similar to other ribosomal proteín genes isolated from potato (TUBS19 and TUBL7), supporting the hypothesis that plant ribosomal protein genes are coordinately regulated. In stolon tips that were not induced to tuberize there was a very low level of expression. When visible swelling of the stolon tip had commenced, high levels