This work represents an attempt to facilitate the automatic accessto the spontaneous Portuguese data for studies on experimentalphonetic area and speech synthesis, maintaining qualitative andquantitative information of the data. This corpus constitutes morethan 30 hours of recording with samples of two Portuguese spokendialects in Amazonia Region: the Amazon Portuguese (AM) and theAfro-Brazilian Portuguese (ABP). As a baseline, samples of the StandardBrazilian Portuguese (PB) were also used. The corpus inventory,the digitalization of the speech data and the phonetic segmentationusing the PRAAT software preceded the construction of the oral database.Using language HTML and other resources of computer science adocumentation of the database in a Internet site becomes possible.


Different approaches to determination of the content of pedagogical research and its typology are examined in the article; complexity, ambiguity and dynamicity of pedagogical concept are also emphasized.


Technology of today makes it possible to change the way traditional healthcare is conducted. As the population grows older, and the elderly is becoming an increasing part of the whole population, t ...


An accurate, high-resolution 3-D earth model is crucial to the seismic calibration for nuclear monitoring. We use the newly developed Finite Frequency Seismic Tomography (FFST) approach to construct the crustal and mantle structure beneath eastern Eurasia. Traditionally, travel times of seismic waves are calculated based on the ray theory, which is valid strictly for infinite-frequency waves. Observed seismic waves, however, are finite frequency signals. As a result of scattering and diffractive effects, travel times of realistic finite frequency waves are sensitive to 3-D structure around the geometrical rays, and the travel time shifts caused by heterogeneities diminish gradually from the heterogeneities to receivers a phenomena named the wave front healing. The ray theory ignores this ubiquitous effect of the propagation of realistic seismic waves. Tomographic inversions based on it, therefore, tend to underestimate the magnitudes of heterogeneities. The newly developed FFST utilizes the 3-D Born-Fréchet sensitivity kernels of the travel times of finite-frequency seismic waves. The new method accounts for the wave front healing, off-ray scattering and other non-geometrical diffraction phenomena, and significantly improves the resolution of the velocity heterogeneity. In addition to the new methodology, we will use a more comprehensive data set than in previous studies to construct the new earth model beneath eastern Eurasia. We will collect data from the publicly accessible sources e.g., Incorporated Research Institutions for Seismology (IRIS), Global Seismographic Network (GSN), the Program for the Array Seismic Studies of the Continental Lithosphere (PASSCAL), and International Monitoring System (IMS) stations. Efforts will also be made to collect data sets from other networks in the region such as the Japanese Broadband Seismograph Network (F-net), the Japanese International Seismic Network (JISNET in Indonesia), and the Taiwan Broadband Seismic Network. Access to other unique sources including permanent and portable seismic stations throughout the study area further improves the station coverage over eastern Eurasia. This is the beginning of a three-year effort to improve seismic calibration in eastern Eurasia. We will first develop a 3-D FFST velocity model using body waves, along with model uncertainties. Travel time corrections and modeling error surfaces will be derived and applied to relocating ground truth (GT5) events. The final model will be developed using joint body and surface waves. From the 3D velocity models, we will also simulate the full wave propagation in the transition zone. To facilitate data integration, a project database and a web-based tool are being implemented. 479 27th Seismic Research Review: Ground-Based Nuclear Explosion Monitoring Technologies


How to design software and hardware of PET bottle defect detection system based on SOPC is introduced.The NIOS Ⅱ soft-core is used to be as the controller in the FPGA chip EP2C35F6726C.Designing some interface modules and user-defined logic modules on the Avalon,using C++ program to achieve image processing in the NIOS Ⅱ,also some peripheral components is needed in the system design.The results show that the design is feasible and reliable,efficient and accurate test.It has some help on parallel image processing,at the same time,prove that FPGA method in image processing is superior.Using FPGA parallel processing method to achieve image recognition.The system is high efficiency,high integration,low cost and easy maintenance.


Abstract 734 The therapeutic principle of antibody-drug conjugates (ADCs) in cancer relies on an antibody to deliver a cytotoxic agent into malignant cells that express a tumor-associated antigen. Recent progress in the field has shown that the use of such conjugates can increase drug activity and reduce cytotoxicity through selective targeting. Recently, TOSO/FAIM3 was identified as the long sought FcR for IgM (FcμR). FcμR is a transmembrane protein expressed on CD19+ B cells, on some CD4+/CD8+ T cells, and weakly on CD56+/CD3− NK cells. We and others have shown that FcμR is consistently overexpressed on chronic lymphocytic leukemia (CLL) cells compared to normal B-cells. In addition, we detected FcμR expression in the mantle cell lymphoma cell line Mino. Using immunofluorescence staining, we found that FcμR can rapidly internalize IgM and transport it through the endocytic pathway to the lysosome. Interestingly, aggregation of FcμR with IgM lead to rapid internalization (>80% internalized within 5 minutes, n=5) whereas mAb bound FcμR was not internalized (n=3). Because of its restricted expression on CLL cells, its cell surface localization and its rapid internalization, FcμR represents an excellent target to deliver a cytotoxic drug into CLL cells using an ADC. To make use of the rapid internalization of FcμR when bound by the Fc-portion of IgM, we engineered a protein scaffold derived from the CH3-CH4 IgM constant region, and inserted a C-terminal selenocysteine, that allows site specific and covalent conjugation of drugs to the protein scaffold. Using gel filtration, we found that purified CH3-CH4 exists mostly as a multimer including pentameric and hexameric forms, similar to native IgM. First, we verified that the CH3-CH4 protein scaffold also binds FcμR, is internalized and addressed to the lysosomes. Next, we conjugated the CH3-CH4 protein scaffold to cemadotin, a synthetic anti-mitotic agent that inhibits tubulin polymerization. This CH3-CH4-cemadotin conjugate was designed to specifically release the drug inside the cell by inserting a peptide linker that can by cleaved by cathepsin B in the lysosomal compartment. In vitro cell killing showed that this CH3-CH4-cemadotin conjugate potently and selectively killed FcμR expressing cells (IC(50) 31 μM). Control experiments showed equal, i.e. non-selective cytotoxicity of free cemadotin against FcμR expressing and non-expressing cells and absence of cell killing with the unconjugated CH3-CH4 protein scaffold. Taken together, these data identify FcμR as a promising therapeutic target in CLL and possibly select other malignanices. IgM-derived scaffolds constitute ideal carriers for drugs or toxins as they are rapidly internalized. In addition, trafficking of IgM scaffolds to the lysosome provides an additional layer of selectivity as a precursor inactive drug can be activated through lysosomal peptidases. Ongoing efforts aim to test modifications of the scaffold and evaluate additional cytotoxic drugs. Furthermore, we are scaling up production of the lead scaffold drug conjugate in order to test its efficacy in xenograft mouse models. This work was supported by the Intramural Research Program of the National, Heart, Lung and Blood Institute. Disclosures: No relevant conflicts of interest to declare.


Based on data on the X-ray spectrum of the Coma cluster, interpreted as thermal bremsstrahlung, the expected brightness depletion from Compton scattering of the microwave background in the direction of the cluster is computed. The calculated depletion is about one-third that recently observed by Gull and Northover, and the discrepancy is discussed. In comparing the observed microwave depletion in the direction of other clusters which are X-ray sources it is found that there is no correlation with the cluster X-ray luminosity. Consequently, the microwave depletion observations cannot yet be taken as good evidence for a thermal bremsstrahlung origin for the X-ray emission. The perturbation from Compton scattering of photons on the high-frequency (Wien) tail of the blackbody distribution is computed and found to be much larger than predicted in previous calculations. In the Wien tail the effect is a relative increase in the blackbody intensity that is appreciably greater in magnitude than the depletion in the Rayleigh-Jeans domain.


We derive and demonstrate an invariant imbedding method for calculating the S matrix for scattering problems involving a first derivative term in the Schrodinger equation for the relative motion. This method can be used directly on scattering problems derived using molecular structure calculations that determine adiabatic potential energies and their derivative coupling matrix elements. A critical discussion of the procedures that transform from an adiabatic to a diabatic representation is presented.


The focus of the study concerns about quality of work life of technical and non-technical employees of ceramic industry. Today in competitive world the biggest challenge is the retention of employees. And it is very important to study the factors that create imbalance between work and life in the life of both types of employees. Sample carries 118 of technical and non-technical employees of ceramic industry. Data was collected through structured questionnaire. Study conduct and found that there are some factor leads to high satisfaction and work or life related issues affecting each other.


We give a method for computing the syzygies of the coordinate ring R of an affine toric variety. We show how the method works for dimension one and two cases, Cohen-Macaulay semigroups, and for computing minimal generators of the defining ideal. We show how to compute the depth of R and generalize a criterion for Cohen-Macaulayness.


We report a finite temperature micromagnetic method (FTM) that allows for the calculation of the coercive field of arbitrary shaped magnetic nanostructures at time scales of nanoseconds to years. Instead of directly solving the Landau-Lifshitz-Gilbert equation, the coercive field is obtained without any free parameter by solving a non linear equation, which arises from the transition state theory. The method is applicable to magnetic structures where coercivity is determined by one thermally activated reversal or nucleation process. The method shows excellent agreement with experimentally obtained coercive fields of magnetic nanostructures and provides a deeper understanding of the mechanism of coercivity.


Using Monte Carlo simulation techniques, we focus on the physical gelation behavior and conformation change under the existence of additional monovalent salt, which provides screening to the electrostatic interaction of charged telechelic polyelectrolyte chains and causes new balance between hydrophobic interaction of end groups and electrostatic interaction originated from the polyelectrolyte blocks. For the electrostatic interaction dominated system, the screening effects will decrease the electrostatic repulsion between small sized clusters and enable the further aggregation of TP chains, resulting in prompting the sol–gel transition progress; for the short-range attraction dominated system, the screening effects present a complicated phenomenon, which includes the prompting effect at the beginning of sol–gel transition and a hindering effect when the gelation progress is close to an end.


Pregnant women are a natural process, the possibility of experiencing physical and psychological changes. Which can cause pregnant women to experience discomfort. Among the third trimester discomforts in pregnant women, low back pain is the most commonly reported and often occurs in 60%-90% of pregnant women. With the aim of knowing the description of low back pain during the third trimester of pregnancy at PMB Anang Arief. This article uses a descriptive method that aims to create an objective picture of the situation, from data collection by history taking, examination, data analysis and documentation. The results of anamnesis that pregnant women are currently 9 months old with low back pain, the results of the examination of the mother's general condition are good and no problems are found, so that they can be analyzed and given appropriate management such as how to overcome the discomfort of low back pain. From the data that has been collected, it can be concluded that the general condition of the mother and baby is in good condition with low back pain discomfort.


If a person has cause to doubt the validity, in the eyes of the roman catholic church, of the marriage contract into which he or she has entered, it is possible to refer the matter to an official marriage tribunal; the latter is endowed with the authority to pronounce the marriage null and void, should this prove to be the case. This dissertation presents the results of an enpirical study conducted among 20 persons whose cases were pronounced on heard by the ecclesiastical tribunal of the diocese of rottenburgstuttgart. These laypersons were questioned on how they perceived five technical expressions frequently used in tribunal hearing. These expressions were as follows: the mullity of a marriage, the matrimonial hearing, the marriage tribunal, the petition, and the witness. The author adopts a wide definition of "perception" encompassing all the effects language has on an individual (cognitive and emotional reactions and behavioral patterns) and including the operant psychological and sociological factors (age, profession, copnfession, experience). Not only do these factors constrain him in concrete communicative situations, but they can also affect the way he @perceives particular expressions. This study is based on the contents of 20 recordel and transcribed interviews. Analysis of these empirical case histories shows that, apart from particular perceptions specific to the individaul in question, a certain number of shared perceptions do exist of several terms and of several persons. Also commented or are the perceptions associated with tribunals of civil society, likewise what it feels like to be accused and to have to defend oneself (and to be uncertain e. G. As to the outcome).


In Portugal, two sports systems exist, one through schools and the other in community clubs. The purpose was to determine the impact of extra-curricular sports (EC sports) on boys' and girls' moderate to vigorous physical activity (MVPA). 208 adolescents (79 boys and 129 girls), between 12 and 18 years old, wore an accelerometer over seven days. Four EC sport categories based on reported involvement were: no sports, school sports, club sports, both sports. Multivariable logistic regression was used to study the association of EC sports, age, gender and BMI on the adolescent's MVPA. The school sport context was more relevant for girls than clubs sport; however the opposite pattern emerged for boys. BMI was not related to adolescent's MVPA. EC sports increase the likelihood of achieving PA guidelines. The unique social and environmental contexts of school and club sports deserve additional attention in youth activity research.


A new algorithm for particle tracking has been developed in order to improve its trackability for flows in which considerable acceleration acts locally. This algorithm consists of two main stages. At the first stage, the particle tracking method using the Kalman filter "type P" is applied in order to estimate individual particle states ; then the measuring region is divided into subregions for the purpose of evaluating local statistics of the particle velocity and acceleration. At the second stage, a new type of Kalman filter which can take account of the local acceleration statistics is applied to tracking particles. Numerical simulations using a 2-D cavity flow are performed for accuracy tests of the present algorithm. As a result, it is proved that the present method achieves measurements with sufficient precision even when the flow direction changes rapidly due to the effect of large acceleration.


SWER lines, with increasing load demand over time, begin to experience voltage sags during peak periods most often in little over half their asset life. Voltage sags are due most often to the lossy nature of SWER networks, and in lines over 100km, there is reserve thermal capacity to allow for use of LV customer voltage regulators. This paper provides methodologies as to how far toward the theoretical maximum power transfer point this can occur, as well as design considerations for the LV voltage regulators.


The lattice dynamics of crystalline Li22Pb5 is studied by means of computer simulations. The calculated spectrum shows several bands corresponding to modes in which only the light atoms execute motions. The spectrum of acoustic modes is found to be well separated from the high-frequency bands and is in all cases confined to frequencies below 4 meV. The results are shown to provide a clue for the understanding of the origin of the strong anomalous dispersion features found in the melt by experiment @Phys. Rev. Lett. 80, 2141 ~1998!# and molecular dynamics simulations @Phys. Rev. E 58, 4568 ~1998!#. @S1063-651X~99!10003-5#


The deviations of state of health of examined adolescents bringing up at a board school were determined with the individual biological peculiarities of premorbid personality (hereditary propensity for alcohol and mental diseases), and also with interruption of social micro-environment (family alcoholism, one-parent family, unfavorable psychological climate at the family).


Achieving effective performance of human resources is primary goal of every organization. In this regard performance appraisal practice of human resource provides the basis of evaluating and developing employee performance for achieving more enhanced organizational success. Similar to any organization, universities or higher education institutions evaluates its employees/teachers performance for effective human resource management. Although, both teaching and non-teaching (administrative) staff in universities play an vital role in improving and maintain the organization's performance, however teachers are considered to be crucial human resource of higher education institutions. Performance evaluation of teachers in terms of their teaching and research outcome is the main area of concern for any university in developing countries like Pakistan. The aim of this study is to investigate the impact of performance appraisal on job performance of teachers in private universities of Khyber Pakhtunkhwa province of Pakistan. Keywords: Performance Appraisal and Employees' Performance, Universities, developing countries


Objective Total triterpenes were extracted from Fomes officinalis ames with response surface method.Methods The ultrasonic-assisted extraction process of total triterpenoids from Fomes officinalis ames was studied.Based on the experiment of single factor,the mathematical regression model was established about the dependent variable(extraction yield of triterpenes) and independent variables(Ultrasonic frequency,extraction time,extraction temperature) through Box-Benhnken center composite design and response surface methodology.Results The optimum extraction conditions were as follow:Ultrasonic frequency was 70 Hz,extraction time was 35 min,extraction temperature was 40 ℃.Conclusion Total triterpenoids extract experiment proved that there are good fitness between the predicted and actual value.


There is no adequate treatment for older patients with AML who are not considered fit for intensive chemotherapy who comprise a significant proportion of the AML population. As part of the ongoing NCRI (formerly MRC) AML14 Trial in patients over 60 years patients were randomised to Low Dose Ara-C (20mg bd for 10 days every 4–6 weeks) versus Hydroxycarbamide (Hydroxyurea). Because of preclinical studies showing sensitization to Ara-C, patients were in addition randomised to receive All-transretinoic acid or not (45mgs/m2 for 60 days). Two hundred and four patients entered; 129 had a WHO score of 65 yrs; 108 had do novo, 53 secondary disease and 28 had high risk MDS (blasts >10%). One hundred and ninety-nine patients entered the HU vs LD-Ara-C randomisation and 204 entered the ATRA randomisation. The arms were balanced with respect to age; sex; disease type; WBC and performance score. Complete remission was seen in 1 of 92 (1%) patients in the HU arm and 15 of 94 (17%) in the LD Ara-C arm (P=0003). Overall survival was considerably improved (hazard ratio 0.61, 95% Cl 0.45 to 0.82, p=0.001). This improvement in outcome was not obtained at the expense of less well tolerated treatment: toxicity and supportive care requirements were similar between the two groups. However, there were no significant differences in outcome between patients given ATRA or not overall or within the treatment arms, although numbers were too small to rule out moderate benefits or disbenefits of treatment (hazard ratio for OS 0.97, 95% Cl 0.73 to 1.28, p=0.8). We conclude that LD-Ara-C in the schedule chosen could be adopted as a standard of care for older patients not fit for intensive chemotherapy but the outcome remains poor. Future strategies could combine Low Dose Ara-C with novel agents. This trial received a research grant from the UK Leukaemia Research Fund.


It is unknown whether activation of hepato-portal vein (PV) glucose sensors plays a role in incretin hormone amplification of oral glucose stimulated insulin secretion (GSIS). In previous studies PV glucose infusion increased GSIS through unknown mechanisms, perhaps neural stimulation of pancreatic beta cells and/or stimulation of gut incretin hormone release. Thus, there could be a difference in the incretin effect when comparing GSIS with portal rather than leg vein (LV) glucose infusion. Plasma insulin and incretin hormones were studied in six overnight-fasted dogs. An oral glucose tolerance test (OGTT) was administered then one and two weeks later the arterial plasma glucose profile from the OGTT was mimicked by infusing glucose into either the PV or a LV. The arterial glucose levels were nearly identical between groups (AUCs within 1% of each other). Oral glucose administration increased arterial GLP-1 and GIP levels by >6-fold while they were not elevated by PV or LV glucose infusion. Oral glucose delivery was associated with only a small incretin effect (arterial insulin and c-peptide were 21±23 and 24±17% greater, respectively, during the first hour with oral compared to PV glucose, and 14±37 and 13±35% greater in oral vs LV; PV vs LV responses were not significantly different from each other). Thus, following an OGTT incretin hormone release did not depend on activation of PV glucose sensors and the insulin response was not greater with PV compared to LV glucose infusion in the dog. The small incretin effect points to species peculiarities, perhaps related to diet.


In the West German centers of theatrical activity such as Berlin, Hamburg, Dusseldorf, Frankfurt, and Stuttgart, Shakespeare seems to have suffered an eclipse during 1984. There were few productions and none notable, with the exception of Hans Lietzau's King Lear and Alfred Kirchner's The Merchant of Venice, both at the Residenztheater in Munich (see Klaus Bartenschlager's accompanying review) and, at the Kammerspiele in the same city, Dieter Dorn's presentation of Der Park, an adaptation of A Midsummer Night's Dream by Botho Strauss. Several important directors have announced ambitious plans for 1985, so the lull promises to be of short duration. However, it gave this reviewer a chance to investigate some of the less well-known theatres, which often do astonishingly creative work without ever making headlines in the national dailies. It proved a highly instructive tour; in only one case did it justify any prejudices I might have had against provincial theatre; in every other case they were vigorously and imaginatively refuted. The start was inauspicious. Bielefeld, a humdrum manufacturing town in Westphalia, has an enterprising municipal company with good actors and a knowledgeable director. Why then should their Romeo and Juliet fail? At first glance, it would not seem a difficult play to bring off. The swift pace of its action, the gripping antithetical structure of its dramaturgy, the gallery of high-colored characters, all make for a successful theatrical event. Markus Weber and his troupe exploited this dramatic potential in the best traditional manner: by clever use of the stage (a construction permitting playing at different levels as well as depths), by highlighting the sensational elements of the action, and by relying on the company's veterans for the character parts. But it all was to no avail-neither the company's fluid use of the varied acting space with its beautiful, illuminated backdrops, nor the focusing of hostility between Capulets and Montagues in hair-raising clashes between a murderous, blood-and-guts Tybalt and a blithely contemptuous Mercutio. It was a fine production, yet one with a hollow core because nothing stirred in the love scenes. Romeo and Juliet went through all the right motions, but-perhaps for this very reason-their emotions remained unconvincing. Watching this production taught one to have more patience with the seemingly rad-


In a seminal work, S.A.R. Horsley and collaborators [S.A.R. Horsley {\em et al.}, Nature Photon. {\bf 9}, 436 (2015)] have shown that, in the framework of non-Hermitian extensions of the Schr\"odinger and Helmholtz equations, a localized complex scattering potential with spatial distributions of the real and imaginary parts related to one another by the spatial Kramers-Kronig relations are reflectionless and even invisible under certain conditions. Here we consider the scattering properties of Kramers-Kronig potentials for the discrete version of the Schr\"odinger equation, which generally describes wave transport on a lattice. Contrary to the continuous Schr\"odinger equation, on a lattice a stationary Kramers-Kronig potential is reflective. However, it is shown that a slow drift can make the potential invisible under certain conditions.


This study proposes a genuine robot accommodating passing movement organizer to be utilized in swarms. The proposed technique figures out how to pass people on foot with smooth speed increase and deceleration by utilizing passing movement learning. A critical element of the proposed strategy is that it is prepared on a basic group reenactment with both dynamic and fixed people on foot. The mastered passing way of behaving can be utilized straightforwardly in an independent route. Assessments utilizing the group recreations demonstrate that the proposed technique beats the current ones as far as progress rate, appearance time, and staying away from the walkers. The proposed route structure is carried out on a versatile robot and exhibited its effective route between walkers in a science gallery.


This paper introduces the design process and working principle of the intelligent traffic vehicle through three major aspects: mechanical structure design, circuit design, and control program algorithm design of the intelligent traffic vehicle. The whole vehicle is divided into a master computer and a slave computer. The master computer uses Baidu's edge board algorithm card to achieve prediction and machine vision recognition processing by deploying trained neural network models. The slave computer uses an embedded system to receive commands from the master computer to decode the data packets and control the actuators to complete the corresponding actions. Finally, we design a smart vehicle that can realize unmanned driving in simple environments. It also can complete corresponding tasks according to the master computer commands.


Repeated within- and between-subject modeling of the human sperm transcriptome to identify dynamic and stress-responsive sncRNAs. Cross Talk opposing view: The kids will be fine – a bit of parental stress won't affect them: Rodents are not good models for assessing transgenerational influences in humans. Physiology


This paper discussed the reliability of computing the road link speed from probe vehicles.A new algorithm for the smallest probe vehicle sampling sizes for traffic flow estimation was proposed.Many factors are considered,such as road style,road link speed and information transmit period of probe vehicle.The field testing using traffic data of Xuhui district in Shanghai presents a good result which validates the effecfiveness of the new model.


Abstract This text explores the return of the Free French to metropolitan territory in 1944–45. The intense emotions provoked by rediscovering the soil of France and their compatriots were succeeded by more mixed and even bittersweet feelings. Very soon, dreams dreamed far away and for many years met the reality of a country deeply wounded by the defeat of 1940 and by the Occupation. The takeover of administrative and political power, and the beginnings of the purges, provoked clashes with the Allies and even more with the metropolitan Resistance, which were essentially quarrels of legitimacy. The violence of the fight for the Liberation mercilessly took its toll. Each and every person who had survived the conflict found the resumption of a personal and intimate life more difficult than expected. Finally, some of the hopes for renovation that had been developed throughout the war began to waver. This led to a frustration tinged with bitterness on which contrasting memories took root.


A vertical-plate balance has been used to measure the surface tension and temperature coefficient of surface tension of liquid sodium and potassium. A value of 200.2±0.6 dyn cm-1 was obtained for the surface tension of liquid sodium at the melting point (97.8°), with a temperature coefficient of -0.11 dyn cm-1 deg-1. For liquid potassium the surface tension was found to be 110.3±1.0 dyn cm-1 at the melting point (64°), with a temperature coefficient of -0.06 dyn cm-1 deg-1. These results are compared with other published values of these quantities. A discussion, based on the statistical mechanics of a quasi-crystalline model of the liquid state, suggests that the chemical impurities present in the liquid metals are unlikely to have significantly increased the surface tension values above those of the pure metals.


In this paper, we consider the minimum-time reorientation problem of an axisymmetric rigid spacecraft with two independent control torques mounted perpendicular to the spacecraft symmetry axis. The objective is to reorient the spacecraft from an initial attitude, with some angular velocity, to a e nal attitude with a certain angular velocity in minimum time. All possible control structures, including both singular and nonsingular arcs, arestudied completely byderivingthecorrespondingformulasand thenecessary optimality conditions. Itisshown that a second-order singular control can be part of the optimal trajectory. It is also shown that for an inertially symmetric and a nonspinning axisymmetric rigid body, it is possible for ine nite-order singular controls to be part of or the whole optimal trajectory. In particular, for a nonspinning axisymmetric rigid body, the second-order singular trajectory is shown to be an eigenaxis rotation. An efe cient method for numerically solving the optimal controlproblem,basedonacascadedcomputationalschemethatusesbotha directmethodand anindirectmethod, is also presented. Numerical examples demonstrate optimal reorientation maneuvers with both nonsingular and singular subarcs, and comparisons are made between eigenaxis rotations and the true time-optimal rotations.


This article gives account of the pedagogical interplay that CLIL could have as an educational approach within a pre-selected undergraduate group of International Business students. It presents a proposal that considers the importance of providing learners with an embedded, functional and curricular model, in which languages and content interrelate simultaneously. In the same line of thought, it suggests a set of materials and resources which could be applied according to particular educational settings, and puts forward a five-step elemental procedure to follow, along with guidelines for teachers to implement CLIL within their university classes.


The incidence of shoulder pain in the general population is around 11.2 cases per 1,000 patients per year. It is considered to be the most prevalent soft tissue pathology, with an estimated incidence of rotator cuff injuries of 3.7 per 100,000 per year. The deterioration of the components of the rotator cuff is one of the most frequent causes of musculoskeletal pain and disability in the world. The conditions of the rotator cuff increase with the age and overuse of the joint, therefore, elderly patients are more affected. This paper presents the development of one soft and portable rehabilitation prototype robot that aims to be evaluated with patients in near future as a suitable device for rehabilitating acute rotator cuff injuries through clinical examinations. The portable robot presented was design from biomechanical analysis and ranges of kinematics and joint dynamics; aspects that determined important requirements for obtaining greater functionality of the prototype ́s portability and with the identification of pre-set tasks that executes two types of specific movements: flexion / extension and external / internal rotation by means of a soft rehabilitation and portable robot device.


Research in both laboratory and field settings has suggested a link between thermal stress and violent behavior, and both linear and curvilinear models have been investigated. A dearth of field studies prompted the analysis reported here, which is based on data for some 10,000 aggravated assaults occurring the City of Dallas in 1980 (a summer of severe heat stress) and 1981. This analysis replicates and extends certain aspects of recent work by Anderson and Anderson (1984) relating to the so-called linear and curvilinear hypotheses. Thermal stress is measured in two ways: a Discomfort Index (DI), which takes into account the influence of humidity acting in concert with temperature, and ambient temperature. Regression analyses were performed in two stages. In the first, data for all neighborhoods and all days of the study period were combined into ambient temperature and DI models. At the second stage, models differentiated between the three levels of neighborhood socioeconomic status. With weekend controlled, DI and ambient temperature were significant independent variables in the 'overall' model and in medium and low status neighborhoods. However, when linear effects were controlled, the curvilinear measures were never significant. The analysis generally tended to confirm Anderson and Anderson's suggestion that a reduction of aggression with increasing temperature does not appear to occur within the normal range of temperatures. This analysis further suggested that the hypothesized curvilinear effect is weak, if not entirely absent, even during conditions of extreme heat.


Objective To study the relation between the infection of human papilloma virus (HPV) and the prognosis of cervical cancer ,exploring the possible carcinogenesis of HPV. Methods The expressions of HPV16/18 DNA in cervical cancers were estimated by in situ hybridization, then the relation between the positive rate of HPV16/18 DNA and the prognosis of cervical cancer was compared in different survival groups. ResultsNinty-four patients with cervical cancer were treated by operation and chemotherapy. The positive rate of HPV16/18 DNA in patients whose survival time were below 10 years (44 cases) was significantly higher than those whose survival time were over 10 years (50 cases)(P0.01). Among the patients classified as clinical stage Ⅱ b , the positive rate of HPV16/18 DNA in those with survival time below 10 years (33 cases) was significantly higher than those whose survival time were over 10 years (35 cases)(P0.01).Conclusions The infection of HPV is closely correlated with prognosis of cervical cancer. The patients showing positive rate of HPV 16/18 DNA tend to have poor prognosis. [


Quantum computing (QC) is fast emerging as a potential disruptive technology that can upend some businesses in the short-term and many enterprises in the long run. Electronic Design Automation (EDA) is uniquely positioned to not only benefit from quantum computing technologies but can also impact the pace of development of that technology. Quantum circuits will play a key role in driving the synergy between quantum and EDA. Much like standard cell libraries became the most important abstraction between CMOS technology and most EDA tooling and spawned four decades of EDA innovation and designer productivity, quantum circuits can unleash a similar streak of innovation in quantum computing.


A method, allowing for the calculation of all matrix elements of the exchange operator between two mesons, is presented. A close formula for such matrix elements is also given, together with graphical rules that allow easy numerical calculations.


The third known species in the genus Colletteichthys is described from Sri Lanka and India. Colletteichthys flavipinnis differs from C. dussumieri in having one instead of two or more tentacles above the eye. It differs from both C. occidentalis and C. dussumieri in having yellow-orange fins, and from C. occidentalis in usually having 16 instead of 15 anal-fin raysand 20 instead of 19 dorsal-fin rays, and in having a slightly smaller ( 1–2% SL) eye. Mitochondrial COI barcode interspecific distance is 4.4% between C. flavippinis and C. dussumieri.


Abstract 2978 Bone marrow infiltration of monoclonal plasma cells can be displayed by magnetic resonance imaging (MRI). While focal lesions - which have been shown to be of prognostic significance in multiple myeloma - can be measured and counted, until now diffuse infiltration could only be estimated qualitatively mainly by subjective comparison of the appearance of the respective vertebra with the intervertebral discs. Diffusion weighted imaging (DWI) which does not require application of contrast medium is established in neuro-radiology as method for early ischemia detection. DWI provides a so called apparent diffusion coefficient (ADC) which hypothetically correlates inversely with cellular density. The measured ADC is dependent of preset b-values with lower values being more influenced by perfusion and higher b-values by diffusion. In our study, we used b-values of 0, 400 and 750 s/mm2 to assess tissue cellularity. In 56 patients with monoclonal plasma cell disease ranging from monoclonal gammopathy of undetermined significance (MGUS) to symptomatic multiple myeloma (MM), correlation of the findings of immuno-histology of a trephine of the iliac crest, cytological smear and apparent diffusion coefficient of DWI of the iliac crest and the lumbar spine were analyzed. Furthermore the DWI-parameters of 30 healthy controls were evaluated for comparison. For histological correlation 25 patients were evaluable. A trend test for comparison of ADC and histological parameters revealed a significantly increasing trend of both plasma cell infiltration level and vessel density compared to ADC (p Disclosures: No relevant conflicts of interest to declare.


The number of pollinators has decreased significantly in the last decades, producing a situation that is frequently mentioned as a "pollination crisis". In our study we document Diptera taxa collected on the early-flowering, legally protected Adonis vernalis L. According to our former observations, species of the Aculeata suborder (Hymenoptera) are the main pollinators of A. vernalis. Besides them many insects visit the flowers of Adonis, thus helping pollination directly or indirectly. Diptera taxa were collected in the spring of 2019 from three sites of the Bakonyvidék Mesoregion in Hungary. At Szentkirályszabadja and Veszprém-Kádárta villages the species Sphaerophoria scripta (19 and 10 individuals, respectively), on the Csatár Hill Chrysotoxum vernale and Pipizella viduata (3–3 individuals) were found the most frequent visitors. At each study site most of the collected insects were members of the Syrphidae family. Of the collected Diptera species only 2 species belonged to the Nematocera suborder, all the others belonged to the Brachycera suborder. At Veszprém-Kádárta we also found three Tephritidae larvae in the flowers.


To efficiently estimate the composition‐dependent thermodynamic properties of fluid mixtures by molecular simulation, a method that adopts a thermodynamic path along a composition profile was proposed. In this method the relative values of both entropy‐related properties, such as free energy, and the ensemble average properties, such as enthalpy, are evaluated as a sum of differences between neighboring composition states along the thermodynamic path. Correspondingly, a simulation with particle transitions, called the particle transition simulation, was used to sample all the composition states along the thermodynamic path. On such paths, the sampling sizes for the calculation are increased significantly because of the statistical equivalence among the particles of each component. The relative thermodynamic properties of all the composition states along the path can be calculated by this approach. This method has been used to estimate excess properties of binary and ternary Lennard‐Jones mixtures in the N...


My Science Tutor (MyST) is an intelligent tutoring system designed to improve science learning by elementary school students through conversational dialogs with a virtual science tutor in an interactive multimedia environment. Marni, a lifelike 3-D character, engages individual students in spoken dialogs following classroom investigations using the kit-based Full Option Science System program. MyST attempts to elicit self-expression from students; process their spoken explanations to assess understanding; and scaffold learning by asking open-ended questions accompanied by illustrations, animations, or interactive simulations related to the science concepts being learned. MyST uses automatic speech recognition, natural language processing, and dialog-modeling technologies to interpret student responses and manage the dialog. Sixteen 20-min tutorials were developed for each of 4 areas of science taught in 3rd, 4th, and 5th grades. During summative evaluation of the program, students received one-on-one tutoring via MyST or an expert human tutor following classroom instruction on the science topic, representing over 4.5 hr of tutoring across the 16 sessions. A quasi-experimental design was used to compare average learning gain for 3 groups: human tutoring, virtual tutoring, and no tutoring. Learning gain was measured using standardized assessments given to students in each condition before and after each science module. Results showed that students in both the human and virtual tutoring groups had significant learning gains relative to students in the control classrooms and that there were no significant differences in learning gains between students in the human and MyST human tutoring conditions. Both teachers and students gave high-positive survey ratings to MyST.


A ferroelectric capacitor over bit-line (F-COB) cell is proposed for high density nonvolatile ferroelectric memories (NVFRAMs). This memory cell with 0.7 /spl mu/m design rule was successfully fabricated using a newly-developed fabrication process, combining CMP and MOCVD techniques. Good ferroelectric properties of storage capacitor, having a remanent polarization of 15 /spl mu/C/cm/sup 2/ and leakage current density of 10/sup -6/ A/cm/sup 2/, have been realized without degradation in CMOS characteristics.


Two experiments were conducted to investigate whether level or source of energy and protein supplementation would reduce the incidence or severity of clinical toxicity in cattle fed forages high in nitrate (NO3). Heavily fertilized sudan hay with 40,000 to 50,000 ppm NO3 was fed in both experiments. The percentage of total blood hemoglobin converted to methemoglobin by nitrate was used to compare treatment effectiveness. Energy supplementation at levels tested in Exp. 1 had no effect on methemoglobin concentration. In Exp. 2, all protein sources (wheat midds, urea, soybean meal) reduced the maximum methemoglobin levels and increased the rate of reconversion to normal hemoglobin.


[Problem] To provide an agent for adsorbing ruthenium from an aqueous solution in order to recover/reuse or remove the ruthenium, and a method for purifying seawater contaminated with radioactive elements and/or water or the like in which sodium ions, magnesium ions, calcium ions, chlorine ions, and the like are included, using the agent. [Solution] The above problem is solved by a ruthenium adsorbent including manganese in an oxide state. The adsorbent may further include at least one transition metal element other than manganese, preferably copper. By immersing the adsorbent in water, the adsorbent can adsorb and remove radioactive ruthenium and the like, and purify seawater and/or water or the like in which sodium ions, magnesium ions, calcium ions, chlorine ions, and the like are included.


Neuroscientific pursuit of music is of growing interest. Literature shows that music enhances neurochemical release, activating the pleasure center of the brain; promotes the secretion of an antibody, enhancing immunity; as well as attenuates and prevents the release of a stress hormone, helping to cope with stressors. These findings demonstrate that music can potentially serve as a scientifically proven medium to exert positive effects on physical and psychological health and well-being. However, research on neurochemical responses to music is still in its infancy and further research is critically needed to determine more specific effects of music. This chapter summarizes existing literature investigating central and peripheral molecular responses to music including neurotransmitters, neuropeptides, hormones, and immune biomarkers, discusses the limitations, and warrants more neuroimaging studies to aim to expand interdisciplinary research in music and neuroscience.


To solve the disadvantages of high energy consumption and low efficiency in hydraulic lift system,an innovative energy-saving technology of variable counterweight is proposed. The energy-saving concept is given and the working principles of two kinds of variable counterweight system are introduced,namely variable hydraulic counterweight and mechanical counterweight with variable speed. And the system applying the variable hydraulic counterweight is discussed in detail,including the installed power,the energy consumption,the efficiency and the poor working condition. Compared with the conventional variable voltage variable frequency (VVVF) hydraulic system,the installed power and energy consumption of the system with variable hydraulic counterweight decreases by 67% and 35% respectively,and the efficiency increases 30%,which means the system saves energy remarkably. Then the problems of the system are discussed,mainly involving efficiency,dynamic response and so on,and the solutions are presented. Finally,the development of the variable counterweight technology is prospected.


Forests influence climate through physical, chemical and biological processes affecting atmospheric composition, planetary energy and the hydrological cycle; these non-linear and complex interactions can amplify or dampen anthropogenic climate change. Forestation and reforestation attenuate global warming by carbon sequestration; and biogeophysical feedback can improve or reduce this negative climate force. Forests mitigate warming through evaporative cooling; and the albedo under the forests generates a positive forcing climate; the evaporative effect of forests is not clear, and the forcing climate of these processes is unknown, forests are under the enormous pressure of global change. Research on the climatic, atmospheric and ecological impacts of forest fires has grabbed attention. However, little is known about the impact of climate changes on vegetation and forest fires. The response of vegetation to fire is characterized by the degradation of communities of xerophytic and pyrophytic plants, dominated by grasses and invasive of fire tolerant shrubs. Climate change can affect forests by altering the frequency, intensity, duration and timing of fire, drought, introduced species, insect and pathogen outbreaks, hurricanes, wind or rainstorms, or landslides. This work addresses the main interactions of fire, vegetation and atmosphere; the predictions on climate change impacts highlight possible impacts on forest biomes, and the parameters involved in the process.


The Ibibiod Proverb-riddle is a major aspect of the Ibibiod communication events. The nomenclature Proverb-riddle is controversial. Some have defined it verbally as a double riddle, a double proverb, a tonal riddle, a rhyming riddle and a two sentence proverb, etc. A Professor of Education, Umoh Susan (2007), proffers a definition which the essay prefers to use in the study. She explains that a proverb-riddle combines the properties of a proverb and a riddle. She describes the components of a Proverb-riddle as a Question (Q), Answer (A), Tone (T), and Rhythm (R). She goes further to justify the riddle component since it poses a question, and the proverb component since it provides the answer. She further explains that the same rising and falling pitch recurrence pattern is used in both Question and Answer components.


From"Breeding"to"Death of Political Adolescent"by Kenzaburo Oe,the post-war re-enlightenment consciousness becomes more and more clearly seen,and his unique enlightenment language has come into being.In the consciousness there appears democratic spirit and his deep worry about Japan's special democratic system.By emphasizing the post-war situation and the individual existence in Japan,Kenzaburo Oe exposes the fragility of democracy and the cruelty of Japan's imperial system.He warns that the post-war distortion of values results in the nationalism thinking,and thus delivers his post-war re-enlightenment consciousness.


To study the role of anti‐idiotypic antibodies in the regulation of the immune response to Lol p I (the major allergenic component of rye grass pollen), we have recently generated a panel of three MoAbs directed against distinct epitopes of Lol p I and an anti‐idiotypic MoAb directed against the idiotype borne by one of the anti‐Lol p I MoAbs (290A‐167). The effects of pretreatment with this anti‐idiotypic MoAb in BALB/c mice before immunization with the antigen have been examined. The anti‐idiotypic MoAb or unrelated MoAb were given weekly for 8 weeks intraperitoneally. Mice then received the antigen (2 μg) adsorbed with alum (2 mg) at weeks 9, 11 and 13. Serum anti‐Lol p I antibodies (IgG or IgE) and specific idiotypic responses were measured. Anti‐Lol pI IgG antibodies could be detected before immunization with Lol p I only in mice pretreated with anti‐idiotypic MoAb. Immunization with Lol p I induced an anti‐Lol p I IgG response in both groups, but this response was higher in mice that received anti‐idiotypic MoAb. Similar profiles were seen for specific IgE antibodies and idiotypic responses. Surprisingly, idiotypes borne by other anti‐Lol p I MoAbs (539A‐6 and 348A‐6) had also been enhanced after pretreatment with the anti‐290A‐167 MoAb. These observations suggested that the pretreatment with this anti‐idiotypic MoAb modulates not only the expression of the respective idiotype, but also affects other idiotype responses.


The complexation between (2‐hydroxypropyl)‐γ‐cyclodextrin (HP‐γ‐CD) and water‐soluble betulin derivatives, betulin 3,28‐disulfate (DSB) and betulin 3‐acetate‐28‐sulfate (ASB), belonging to the class of pentacyclic lupane triterpenoids, was studied using mobility shift ACE (ms ACE). It was found that the complexation is a high‐affinity interaction. In this case, a very low amount of HP‐γ‐CD should be added to the BGE, and triangular peaks are observed as a result of ligand deficiency in the sample zone. Le Saux et al. showed in 2005 that using the parameter a1 of the Haarhoff‐Van der Linde (HVL) function instead of the migration time measured at the peak apex eliminates the effect of ligand deficiency on effective electrophoretic mobility. Therefore, the electrophoretic mobilities of asymmetrical peaks of DSB and ASB were calculated in this way. The obtained experimental data correspond to 1:1 complexes. The calculated values of binding constants logarithms at 25°C are 6.70 ± 0.05 and 7.03 ± 0.10 for the HP‐γ‐CD complexes of DSB and ASB, respectively.


The utility model discloses a modular stupefied device of back of body is consolidated to adjustable template that the commonality is good, reuse rate is high, construction quality is good, easy dismounting is quick, the stupefied device of this back of the body can be used to the concrete member's of various shapes and size template and consolidate. The utility model discloses a L type back of the body stupefied (1) for template (9) corner, a style of calligraphy back of the body stupefied (2) for template (9) straight line trend, an intermediate junction back of the body stupefied (3) for inciting somebody to action the L type back of the body stupefied (1) is connected with the style of calligraphy back of the body stupefied (2) and adjacent two the one styles of calligraphy back ofs the body stupefied (2) or adjacent two L types back ofs the body stupefied (1) connection, a split bolt subassembly (4) that is used for the L type back of the body stupefied (1) that corresponds the template of relative both sides (9) or stupefied (2) are carried on the back to a style of calligraphy or the intermediate junction back of the body stupefied (3) is connected, insert the length of the L type back of the body stupefied (1) and the style of calligraphy back of the body stupefied (2) between the intermediate junction back of the body stupefied (3) and the L type back of the body stupefied (1) and the style of calligraphy back of the body stupefied (2) through the adjustable intermediate junction back of the body stupefied (3) of pegging graft, not unidimensional template with the shape with the adaptation is reinforced. The utility model discloses but wide application in building templates field.


This article explores the idea of experience in Surrealism through the writings of André Breton and Leonora Carrington. Breton's founding manifestoes of Surrealism and novel Nadja (1928) make the claim for a revolutionary experience of the everyday world. However, the feminine tropes he uses clearly valorize an experience based on masculine perception. Additionally, in the years leading up to and following World War II, Surrealism was decried for not engaging with history or politics. Carrington's narrative Down Below (1944) addresses both Breton's concept of experience and Surrealism's historical force by demonstrating a negotiation between Surrealist aesthetics and its nefarious gender politics; further, Carrington also relocates Surreal experience into corporeal and historical registers. By choosing Carrington for inclusion in his postwar Surrealist Anthologie de l'humour noir, Breton reveals the extent to which he addressed interwar Surrealist politics and tried to shape the future of Surrealism as a movement.


The incremental construction of nested designs having good spreading properties over the d-dimensional hypercube is considered, for values of d such that the 2 d vertices of the hypercube are too numerous to be all inspected. A greedy algorithm is used, with guaranteed efficiency bounds in terms of packing and covering radii, using a 2 d−m fractional-factorial design as candidate set for the sequential selection of design points. The packing and covering properties of fractional-factorial designs are investigated and a review of the related literature is provided. An algorithm for the construction of fractional-factorial designs with maximum packing radius is proposed. The spreading properties of the obtained incremental designs, and of their lower dimensional projections, are investigated. An example with d = 50 is used to illustrate that their projection in a space of dimension close to d has a much higher packing radius than projections of more classical designs based on Latin hypercubes or low discrepancy sequences.


A nerve cell death inhibitor, an anti-Alzheimer's disease agent, a brain hypofunction inhibitor and a drug or food having an anti-Alzheimer's disease effect or a brain hypofunction-inhibiting effect, each containing as an active ingredient "a preset partitioned portion that is a portion partitioned in methylene dichloride when an ethanol extract of Rhinacanthus nasuta (L.) Kurz is liquid-liquid partitioned with hexane and methanol and then the portion partitioned in methanol is liquid-liquid partitioned with methylene dichloride and water", "a preset fraction that is a fraction eluted from a silica gel column with an elution solvent, said elution solvent consisting of n-hexane, ethyl acetate and anhydrous methanol, when the preset partitioned portion is subjected to silica gel column chromatography using the elution solvent" or Rhinacanthin C.
According to the present invention, a nerve cell death inhibitor having an excellent effect of inhibiting nerve cell death, an anti-Alzheimer's disease agent, a brain hypofunction inhibitor and a drug or food having an anti-Alzheimer's disease effect or a brain hypofunction-inhibiting effect can be provided.


From the view of business process, we analyze and design the wor&7ow management system for virtual enterprise(VE,), which is distinguished fiom traditional management of enterprise based on division of function module. Mobile intelligent agent is the basic unit for the management of business processes that realizes the independence and autonomy of dynamic VE. Independent of any other business domains, virtual market plays a centralized role in system cooperation.


Changing raw material base for the production of aluminium and the emergence of a huge number of secondary glinozemservice waste (foundry slag, sludge, spent catalysts, mineral part of coals and other are formed in various industrial enterprises) demanded the creation of a scientific and theoretical basis for their processing. In this work, as aluminium-containing component used aluminum alloys (GOST 4784-97), aluminum containing component is obtained as a chip on Mashinostroitel-governmental enterprises. Aluminum waste is a whole range of metal alloys of aluminium with cumtion of the elements: magnesium, copper, silica, zinc, iron. Analysis of waste aluminum Al – Zn – Cu – Si – Fe shows that, depending on the content of a particular metal and the dissolution process of aluminum alloy should be viewed as the result of chemical interaction of the metal with an alkaline solution. It is necessary to consider the behavior of the main components of the alloy in alkaline solution, with respect to the system Na 2 O – Al 2 O 3  – SiO 2  –  ® CO 2  – H 2 O. Since the final contents of the components in an alkaline solution is determined by its soluble Pro-vide experimental evaluation of the possibility of dissolution of iron and other elements of aluminum alloy-VA in alkaline solution of different concentrations at temperature 80-90  ° C., that show that for pH alkaltion of solutions containing 100-300 g/l Na 2 O к y the solubility of ferric hydroxide is (0,003-0.05) g/l Fe 2 O 3 .


P. Jonšta, J. Sojka, K. Matocha, Z. Jonšta. VŠB-TU Ostrava, FMME, Ostrava, Czech Republic The paper is focused on the evaluation of duplex ferritic-austenitic steel resistance to sulphide stress cracking (SSC). The testing was performed in accordance with the NACE TM 0177 Standard using tensile tests and four-point bending tests. The steel was always tested in two diff erent structural states, in the as-received state (marked as AR), and after laboratory annealing by the mode of 800 °C/5h/air (marked as AN). Microstructure of steel in the AR state was formed by ferrite and austenite, the AN state was characterized by an disintegration of the part of ferrite and by formation of brittle σ phase. The aim of this study was to evaluate the eff ect of testing methodologies and changes of microstructural parameters of duplex steel resistance to SSC.


Expression of type-1 carbohydrate antigens (CBAs), DU-PAN-2 and CA19-9, was strongly dependent on hormonal regulation during the menstrual cycle in the endometrium. DU-PAN-2 expression was more frequent than that of CA19-9 in endometrial adenocarcinomas (EMACs), with no correlation to menopausal status. The relationship between immunohistochemical profiles and serum values was statistically proven to be closer for DU-PAN-2 than for CA19-9. Although during staging-up the serological positive ratios distinctly increased for both DU-PAN-2 and CA19-9, the serum DU-PAN-2 values tended to decrease according to histological grading-up and the reverse was true for CA19-9. In the analysis of variable thyroid diseases, from the specific and frequent expression of DU-PAN-2 in papillary carcinomas, it was suggested that DU-PAN-2 would be a useful immunohistochemical marker for distinguishing papillary carcinomas from follicular tumors. For testicular germ cell tumors (TGCTs), it could be emphasized that embryonal carcinomas were rather characteristic of extensive DU-PAN-2 expression. Particularly in CA19-9-negative cases, a combined analysis would be helpful in confirming the histologic diagnosis of embryonal carcinoma. The biological significance of characteristic DU-PAN-2 expression as a tumor marker in the above tumors remains to be clarified. The difference in activity of the specific glycosyltransferases, α-2-3-sialyltransferase and α-1-4-fucosyltransferase, may result in the variable expression profiles of these antigens.


This paper discusses where Portuguese physicians studied medicine. The careers of two thirteenth-century physicians, Petrus Hispanus and Giles of Santarem, indicate that the Portuguese travelled abroad to study in Montpellier or Paris. But it is also possible that there were opportunities for study in Portugal itself. Particularly significant in this respect is the tradition of medical teaching associated with the Augustinian house of Santa Cruz in Coimbra and the reference to medical texts found in Coimbra archives. From these sources it can be shown that there was a suitable environment for medical study in medieval Portugal, encouraging able students to further their medical interests elsewhere.


This study examines the incentives in fund management due to the adoption of specific performance measures. A mean–variance measure such as Jensen's alpha incentivizes fund managers to load negative coskewness risk. This risk is shown to be priced in the UK stock market during the period January 1991– December 2005, bearing a premium of 2.09% p.a. Hence, a new performance measure, the intercept of the Harvey–Siddique two-factor asset pricing model is proposed to be more appropriate for prudent investors. Using this model, the performance of UK equity unit trusts is examined for the same period. Though most of the managers significantly underperformed their benchmark, they correctly responded to their incentives, loading negative coskewness and reaping part of the corresponding premium.


The origin and geochemical evolution of formation water trapped in continental shale of the Dameigou Formation in the Northern Qaidam Basin have been investigated for selecting unique signatures of formation water compared with shallow groundwater and conventional oilfield brines (COB). The formation water, which is trapped in a closed shale with no halite and sylvite in it, has a higher Cl/Br ratio (1183.43) than that of seawater (657.89). Furthermore, δ2H (−67‰) and δ18O (−8.1‰) values of the formation water lies near the local evaporation line. These suggest that the formation water originated from evaporated rainwater. The temperature (>120°C) of the Dameigou Formation and the vitrinite reflectance values (1.0-1.3%) of the shale indicate that thermochemical sulfate reduction (TSR) was responsible for the depletion of SO4 in the formation water. The increased CO2 concentration and Mg/Ca ratio in formation water leading by TSR caused kaolinization of plagioclase feldspar and dolomitization, respectively. The formation water depletion in Ca and HCO3 was caused mainly by calcitization. The Na/Ba ion exchange and dissolution of continental borate occurring in the shale-formation water system were vital to the geochemistry of trace elements in formation water. All these geochemical processes have given the formation water distinctive δS-H2S (25.9‰), 87Sr/86Sr ratio (0.713842), Ba/Ca ratio (2.60×10-2) and δ11B (1.1‰) signatures compared with COB in shallow


This article provides an analysis of the main problems that affect the greening of products and their marketing systems, and considers international norms, rules and environmental standards in the field of marine fuel use. The effective solution of the problem and the development of related areas of improvement of the system of introduction of greening of fuel products and its further marketing, including external, information, technological and structural components, are proposed. The development of the market for the sale of liquefied natural gas, research on the creation of fuel with a reduced sulfur content, strengthening quality control in the organizational mechanism for the sale of finished products, as well as increasing the level of greening during transshipment, transportation and bunkering are considered as directions for implementing the goal of greening.


German scientists made substantial and notable contributions to colonial Victoria. They were involved in the establishment and/or development of some of the major public institutions, e.g. the Royal Society of Victoria, National Herbarium, the Royal Botanic Gardens, Museum Victoria, the Flagstaff Observatory for Geophysics, Magnetism and Nautical Science, the Pharmaceutical Society of Victoria and the Victorian College of Pharmacy. Further, they played a leading role not only in scientific and technological developments but also in exploration – Home has identified 'science as a German export to nineteenth century Australia' (Home 1995: 1). Significantly, an account of the 1860 annual dinner of the Royal Society of Victoria related the following comment from Dr John Macadam MP, Victorian Government Analytical Chemist: 'Where would science be in Victoria without the Germans?' (Melbourner Deutsche Zeitung 1860: 192). This paper considers key German scientists working in mid-nineteenth century Victoria and the nature and significance of their contributions to the colony.


Abstract : The saturated drift velocity is a very important parameter of semiconductor crystals. It determines frequency limitation of semiconductor devices and consequently the range of the most effective application. Silicon carbide polytypes are not exclusion, Up to the present such velocities have been determined for two polytypes 4H and 6H SiC for direction perpendicular to crystal axis.


Low-cost, large-area patterning of organic field-effect transistors with high-resolution is a subject of ongoing investigations. Here, we present a concept of patterning vertical-channels organic transistors using excimer laser. The channel length is controlled by the thickness of the dielectric polymer layer between the drain and source electrodes. We demonstrate that, by using this method, patterning of transistors with either metal or polymer contacts with resolutions as high as 2μm is possible. Experimental data of vertical-channel pentacene transistors with either gold or poly (3,4-ethylenedioxythiophene) as drain-source contacts are reported. Field effect mobilities of 1×10−3 and 3×10−4cm2∕Vs, respectively, have been measured in these devices.


Gait has been studied in recent years as one of the newest topics in computer vision as it offers potential for applications in various areas, including biometric identification, medical diagnostics and therapeutic tools. Clinical research has identified a clear link between human gait characteristics and different medical conditions. We are particularly interested in gait and balance analysis for fall risk assessment in elderly people. This dissertation proposes the use of multiple inexpensive web cameras for three-dimensional gait and balance analysis in a voxelized space. The main advantages of this approach include low cost, unobtrusive monitoring compared to wearable sensors, and three-dimensional voxel reconstruction which provides a non-camera view-dependent capability. It is thus suitable for daily assessment and continuous monitoring of elderly people's non-controlled daily living environment.
The gait parameters studied include walking speed, step time and step length; balance was assessed through body sway. In addition, 180° turnaround time and number of steps are also studied. These parameters were obtained from a three-dimensional voxel reconstruction, which is built from two calibrated camera views. These parameters are validated with a GAITRite Electronic mat, a Vicon motion capture system in the lab, and a physical therapy expert rating. Excellent agreements were found for walking speed, step time, and step length between the webcam system and the GAITRite, with no statistically significant difference. There is no significant difference in walking speed and step length comparing the webcam system with the Vicon. Significant difference was observed for step time between the webcam system and the Vicon, as well as between the GAITRite and the Vicon. There is no significant difference in walking speed between the system and the expert, but highly significant difference in step time and step length, caused by the expert's strategy of rounding up the number of steps when there is an incomplete gait cycle. Overall, the walking speed was found to be the most robust and reliable gait parameter captured through all the tests. The body sway and turnaround parameters were also found to have a reasonably good agreement given the limitation of frame rate and voxel resolution.
The system was further tested and validated with assistance of elderly residents from TigerPlace, an independent living apartment complex for seniors in Columbia, Missouri, in scripted scenarios representing everyday activities. The residents were first tested on a GAITRite mat with cameras recording images. The extracted gait parameters from the camera system were compared with the GAITRite; and excellent agreement was achieved. The residents then participated in the scenarios, with only the cameras recording. Parts of the scenario video of 10 participants were evaluated and rated by a physical expert in the research team. The algorithm results matches well with the expert rating. Based on these good validation results obtained in a realistic non-lab setting, further analysis is therefore reliable. Results on 18 elderly participants were analyzed. The analysis showed that the residents displayed different gait patterns when the realistic scenarios were compared to the GAITRite runs. Furthermore, the complete set gait parameters provided a clear picture of a person's gait status and were used to screen out people at risk of falling. This research shows how long-term gait monitoring can provide trend information on a person's gait characteristics and proves the importance of continuous gait assessment in a daily living environment.
Research results indicate that the development of this technology can provide capability of monitoring gait and balance in daily living environment for elderly people, which in turn can be used as part of a continuous balance, stability and fall risk assessment tool.


Pelvic fractures are uncommon but complex injuries associated with a high degree of morbidity and mortality. Most fractures involving the pelvis, specifically the sacrum, can be effectively stabilized with iliosacral screws alone. However, significantly unstable fractures, particularly vertical shear patterns, as well as U-type variant sacral fracture patterns that create spinopelvic instability, require the addition of lumbopelvic fixation. The surgical technique involves neurologic decompression as necessary, multiplanar reduction of the pelvic ring and sacrum, and placement of stable fixation. Treatment of these severe injuries requiring lumbopelvic fixation is challenging and requires active collaboration between spine trauma and pelvis trauma surgeons. Although not routinely used, lumbopelvic fixation is an essential technique for the stabilization of complex pelvis fractures.


They say moving house is one of the most stressful experiences of your life. So imagine the headache of moving a 680-bed hospital spread over eight sites into just one brand spanking new tower block.


Background: Constitutional delay of growth and puberty (CDGP) is the most common cause of short stature. This variant of normal growth can be associated with psychological stress in some affected individuals. Objectives: We aimed to assess the effects of clonidine on short-term growth rate in children and adolescents with constitutional growth delay. Patients and Methods: In this prospective, randomized clinical trial study, 48 prepubertal constitutionally short boys (6 -12 years old) with height standard deviation scores (HSDS) less than -2, bone age delay 2.1 ± 0.2 years, GH concentration > 10 μg/L after provocation and growth rates < 5 cm/year were included. Subjects were randomly assigned to group A (n = 24) who received clonidine 0.1 mg/m2 or group B (n = 24) who received placebo before sleep for 6 months. Height, weight and growth velocity were measured in 6th and 12th months. Results: Mean age and height in two groups were similar at baseline. Mean growth velocity in group A was 2.9 ± 0.91 and 3.1 ± 0.98 cm/6 month at baseline and 6th months, respectively and in group B was 2.9 ± 0.94 and 2.4 ± 0.47 cm/6 month at baseline and 6th months, respectively (P = 0.01). Mean HSDS in group A was -2.79 ± 0.65 and 2.39 ± 0.39 at baseline and 6th months, respectively and in group B was 2.69±0.73 and 2.39 ± 0.48 at baseline and 6th months, respectively. Conclusions: Although a slightly increase in HSDS was observed in treated group, but difference was not significant compared with control subjects. So, clonidine therapy could not improve height standard deviation score and growth velocity of children and adolescents with CDGP.


This article examines the possibilities for the emergence of covenantal pluralism in Nepal. Although recent trends in Nepal indicate a rise in interreligious hostility and conflict, we argue that advocates of covenantal pluralism should be cautiously optimistic about the possibilities in Nepal. While the greatest threat to covenantal pluralism in Nepal emanates from a reactionary Hindu nationalist social movement, legal innovations—including the ambiguity of the definition of the term "secular" in Nepal's 2015 constitution—coupled with existing social resources offer critical sites of opportunity that can be leveraged in efforts to promote covenantal pluralism in Nepal.


On April 28th the Fed announced it would already be loosening the terms of its an unprecedented new Municipal Liquidity Facility ('MLF') for States and their Subdivisions now struggling to address the nation's COVID-19 pandemic. This is effectively 'Community QE2' in all but name. Because Community QE, which is still in the process of being operationalized, will constitute a literal lifeline to States and their Subdivisions, and is in light of its novelty still as unfamiliar as it is essential, this Memorandum briefly summarizes what the new Facility enables now and will likely enable in future. On this basis it then recommends a three-phase 'Game Plan' for States and their Subdivisions to put into operation immediately – that is, during the first week of May.


Recently there has been growing interest in asymptotically anti de-Sitter (AdS) black holes, motivated by the discovery of the BTZ black hole [1] in General Relativity (for reviews see [2,3]) and by the so-called AdS/CFT speculation in string theory [4]. Very recently, Pretorius and Choptuik presented results of fully-nonlinear numerical simulations of the gravitational collapse of a massless, minimally-coupled scalar field in 2+1 dimensional, axially-symmetric, AdS3 spactime in classical General Relativity [5]. Pretorius and Choptuik studied the critical behavior at the threshold of black-hole formation in this model, and found a continuous self-similar solution and type-II behavior with a mass-scaling law with critical exponent ∼ 1.2. This work was followed by Garfinkle [6], who was able to find analytically an exact solution for this model, in agreement with the numerical results of Ref. [5]. Husain and Olivier studied the same model using a different numerical approach and a different evaluation approach for the critical exponent, and reported on a mass-scaling law with critical exponent ∼ 1.6 [7]. This apparent discrepancy of the two estimates for the critical exponent is of great interest. Pretorius and Choptuik also studied in Ref. [5] the nature of the singularity in their model for supercritical evolutions. They report on a scalar curvature singularity, which is spacelike and deformationally strong [8,9]. However, the evidence brought in Ref. [5] appears to be inconclusive. Specifically, Pretorius and Choptuik argue that the singualrity is spacelike because the hypersurface along which the metric variables start growing unboundedly in the normal direction, and consequently the curvature invariants begin to diverge, is spacelike. Although this is consistent with the singularity being spacelike, it is only a necessary condition for it. The mass inflation [10–13] null singularity is a counter-example, where hypersurfaces of constant large (albeit finite) curvature are spacelike, although the singularity itself is null. The evidence that Pretorius and Choptuik bring for the strength of the singularity is that it is central, namely, that the proper circumference vanishes approaching the singularity. This criterion appears indeed to be sufficient evidence in spherical symmetry under very broad conditions [14], but this has never been shown in 2+1D and circular symmetry. In this paper we show, within a simplified model, that indeed this singularity is spacelike, scalar curvature, and deformationally strong. Specifically, we assume that spacetime asymptotically close to the singularity can be described by a quasi-homogeneous model, i.e., we assume that spatial gradients (of the metric functions and the scalar field) are much smaller than temporal gradients. This assumption seems to be justified by the results of Ref. [5], where Figs. 18 and 19 imply only mild gradients tangent to the singularity, and much steeper gradients normal to it. We shall study the solution to the Einstein-scalar equations in 2+1D and circular symmetry only asymptotically close to the singularity. We thus write the metric as


The paper shows the relevance of the problem associated with the diagnosis and treatment of stroke in young patients aged 15-45 years. It considers the major causes of acute cerebrovascular accidents in young people, including pregnant women. Diseases, such patent foramen ovale, mitral valve prolapse, infective endocarditis, and postpartum cardiomyopathy, are described in detail. The basic principles of the diagnosis and therapy of ischemic stroke at a young age are given. The mainstay of therapy for acute ischemic stroke is stated to include two procedures: reperfusion and neuronal protection.


A method for measuring the volume of the peripheral blood flow by using PAH was reported. The values of the plasma flow per 100 cc. of extracellular fluid in forearm per minute was 8.0-25.3 cc. (mean 15.2 cc.) in 22 normal individuals and 11.9-36.1 cc. (mean 18.3 cc.) in 10 hypertensive, and this method is supposed to be able to be applied clinically for estimating the blood flow in organs or tissues, where the assumption, that the mean concentration of PAH in the extracellular fluid is appro-ximately equal to the PAH concentration in the veins, can exist.


Aircraft automation is part of a vast movement to improve and control performance and risks in so-called advanced societies. The paper first describes the current status of aircraft automation, what end user model triggered the present choice, how far can the results be considered a success by the aviation technical community, and how any existing drawbacks are explained and controlled. Next, a brief description is provided of automation drawbacks, and that is followed by a presentation of a causal model based on the mismatch of the pilot's model between industry and academia. The final section focuses on solutions suggested by the theorists to improve the human-machine interface or to assist industry in improving jobs. The relevance, feasibility, and limitations of these suggestions are also considered.


Objective The COVID-19 pandemic has had a significant impact on patient care, including the increased utilization of contact-free clinic visits using telemedicine. We looked to assess current utilization of, experience with, and opinions regarding telemedicine by general surgery residents at an academic university–based surgical training program. Design A response-anonymous 19-question survey was electronically distributed to all general surgery residents at a single academic university–based general surgery residency program. Setting University of Southern California (USC) general surgery residency participants: Voluntarily participating general surgery residents at the University of Southern California. Results The response rate from USC general surgery residents was 100%. A majority of residents (76%) had utilized either video- or telephone-based visits during their careers. No resident had undergone formal training to provide telemedicine, although most residents indicated a desire for training (57.1%) and acknowledged that telemedicine should be a part of surgical training (75.6%). A wide variety of opinions regarding the educational experience of residents participating in telemedicine visits was elicited. Conclusions The COVID-19 pandemic brought telemedicine to the forefront as an integral part of future patient care, including for surgical patients. Additional investigations into nationwide telemedicine exposure and practice among United States general surgery residencies is imperative, and the impact of the implementation of telemedicine curricula on general surgery resident telemedicine utilization, comfort with telemedicine technology, and patient outcomes are further warranted. Competencies Practice-based learning, systems-based practice, interpersonal and communication skills


To study the influence of the stress intensity factor and the R‐ratio on the fatigue crack growth rate different kind of crack propagation experiment have been carried out on the steels X5CrNi18‐10 and C45E. The experiments show that both parameters the maximum stress intensity Kmax and the R‐ratio affect the crack growth rate. Consequently, the authors developed a 3D‐model, which describes the dependence of da/dN on Kmax and the R‐ratio. Discussing the experiments, special attention has been paid to the threshold behavior of the investigated materials. Finally, a new model to describe the influence of the R‐ratio on the threshold Kmax,th for R‐ratios from −∞ to 1 is presented.


Acute appendicitis is the most common surgical abdomen in the pediatric population. However, diagnosis and treatment often are delayed because of the challenge in obtaining an accurate history and physical examination in toddlers and children, which significantly increases the likelihood of appendiceal rupture. Complications such as abscess formation, functional obstruction, and sepsis alter both management and prognosis. This CME activity emphasizes that radiologists must appreciate that although CT scanning is the mainstay in the evaluation of appendicitis, growing concerns regarding ionizing radiation have expanded the use of ultrasound. Findings that would suggest a perforated appendicitis on various imaging modalities are discussed and outlined in this article.


Taking the selenium enriched Pleurotus eryngii produced by Hanyin town in Ankang city as the raw material,three optimal processes were selected to brew mushroom into vinegar in order to obtain high-quality selenium enriched Pleurotus eryngii vinegar through alcohol ferment and acetic acid ferment. The Pleurotus eryngii vinegar brewed by such a process provides a pure flavor and a thick vinegar liquid with a color of limpidly yellow, and it is enriched in nutrients such as amino acid and vitamins, which has favorable development prospect in markets.


Semiconductor InGaAs/GaAs heterostructures grown by molecular beam epitaxy have been studied using low temperature (5K) cathodoluminescence as part of a project to determine the mechanisms of misfit dislocation nucleation. The samples studied contain oval defects which give rise to a large number of misfit dislocations. Also associated with the oval defects is a highly luminescent halo which gives rise to a peak on the low energy side of the InGaAs peak in the CL spectrum. The dislocation density is shown to oscillate along the sample and this oscillation can be partly explained by the presence of the oval defects.


Objectives: Growth hormone secretory capacity of adults decrease with aging, Growth hormone secretory capacity and prevalence of growth hormone deficiency in Korean adults were studied. Methods: History, physical examination, and routine blood tests were performed to roule out ill patients among ordinary subjects. Anthropometry, nutritional history, serum insulin-like growth factor-1 (IGF-1) levels, L-dopa stimulation tests, and urinary growth hormone levels were measured in 309 Korean adults, ages 20-87 years. Results: The mean serum IGF-1 levels were 258,2+6. 8 ng/ml. The mean serum IGF-1 levels of adult males were significantly higher than those of the females. The serum IGF-1 levels decreased with aging. The prevalence of growth hormone deficiency defined by serum IGF-1 levels (< 150 ng/ml) were 0.0% in the 3rd decade, 5.5% in the 4th decade, 12.2% in the 5th decade, 10.0% in the 6th decade, 32.1% in the 7th decade, 48.1% in the 8th decade, respectively. The serum IGF-1 levels were positively correlated with total energy expenditure, but negatively correlated with body fat mass. The peak serum growth hormone levels after L-dopa stimulation and urinary growth hormone levels of the younger subjects were significantly higher than those of the older subjects, There were goad correlations among serum IGF-1 levels, peak growth hormone levels after L-dopa stimulation, and urinary growth hormone levels. Conclusion: Growth hormone secretory capacity decreased significantly with aging, and growth hormone deficiency was found in about 1/3 of subjects aged over 60 years.


This paper designs a TCP-friendly reliable multicast congestion control protocol,named FACC,which falls into single-rate and receiver-driven protocol.In order to achieve TCP friendly fairness,FACC uses a more accurate TCP throughput model.Further,FACC introduces active node to carry out congestion representative filtering.Experiments show that FACC can provide steady sending rate and TCP friend fairness.


Acute myeloid leukemia (AML) is an extremely aggressive disease with a high relapse rate even after allogeneic hematopoietic stem cell transplantation (HSCT). We report the successful outcome of cell‐mediated cytokine‐activated immunotherapy in a high‐risk pediatric AML patient who relapsed shortly after allogeneic HSCT. Donor lymphocyte infusion along with interferon induced a graft‐versus‐leukemia effect, presenting as a reversible episode of graft‐versus‐host disease, which led to stable complete donor chimerism and total eradication of AML for over 24 months, at the time of this report. The curative potential of immunotherapy in hematological malignancies is discussed. Am. J. Hematol., 2009. © 2008 Wiley‐Liss, Inc.


A preparation method for histidine label protein functional carbon nanotube and an application thereof; the preparation method comprises the following steps: firstly preparing carboxylated carbon nanotube; and then further reacting to obtain activated lactonized carbon nanotube; reacting the histidine label protein expressed by the transgenic colibacillus with the activated nanotube to prepare the histidine label protein functional carbon nanotube. The invention develops a simple, fast, economical method for high-sensitively and high-selectively detecting trace metal elements within complex system by making use of the multifunctional decorative characteristic of the carbon nanotube and the high loading characteristic of the nanometre material. The invention can high-sensitively and high-selectively detect the target element when detecting heavy metals or certain excessive metals within the complex system, can eliminate the influence of other elements.


In the article the system of the organization of work with studying youth and graduates is considered. The results of the students' entrance the university on the first course were analyzed. Variants of perfection of the basic aspects of vocational guidance are offered.


The distribution of the total nitrogen in whole blood, red blood cells and serum proteins of the blood in children has been reported in a previous communication. 1 The present article records the results of further studies on the distribution of the amide, humin, hydrolyzable, basic amino and mono-amino nitrogen in the whole blood, red blood cells and serum proteins. METHODS The methods were adapted from those of Van Slyke 2 and Cavett. 3 The procedure for obtaining blood specimens, the separation of red blood cells and the serum proteins from the same specimen of blood and the determination of the total nitrogen have previously been described in detail. 1 Whole Blood. —Five-tenths cubic centimeter of oxalated blood was diluted to 10 cc. with distilled water. One cubic centimeter was removed for the determination of the total nitrogen; the remaining 9 cc. was washed into a 30 cc. Erlenmeyer flask


A kind of self-assembled vesicles that composed of ionic liquid-type cationic gemini surfactant (C3H6-α, ω-(Me2N+C12H25Cl–)2, 12-3-12) and anionic biological surfactant (sodium deoxycholate, SDC) were constructed for Au(III) extraction. The appearance and microstructure of vesicles system were characterized by visual and TEM images. Compared to the zeta potential of pure vesicles system (+45 ± 1 mV), zeta potential of gold-loaded vesicles system reduced 15 ± 1 mv (changed to +30 ± 1 mV), which confirmed the mechanism of Au(III) was effectively extracted by vesicles through electrostatic interaction. The main influence factors including extraction equilibrium time, surfactants concentration, NaCl concentration, and pH on the extraction efficiency (E%) were explored. Furthermore, an effective method was devoted for gold(III) stripping. Through stepwise extraction and ligand-modified vesicles system, Au(III), Cu(II), and Fe(III) were separated from a mixed solution successfully. In short, an effective and po...


Excessive production of IgE plays a major role in the pathology of food allergy. In an attempt to identify anti‐IgE natural products, Arctium Lappa was one of the most effective herbs among approximately 300 screened medicinal herbs. However, little is known about its anti‐IgE compounds.


A simple and fast texture-based technique for the removal of residual ground clutter is presented. Its main advantages are that it is easy to implement (both for polar and Cartesian data) and can be applied a posteriori after any other method of clutter removal has been applied. The per- formances of the technique during clear-sky and rainy con- ditions are analyzed for a 180◊150 km 2 complex-orography region, using data from a non-Doppler and a Doppler radar (for both, approximately 50% of the clear-sky clutter shows average reflectivity greater than 13 dBZ). In the case of the non-Doppler data, the texture-based code is used after a pre- stored static map: it is absolutely necessary and leads to ex- cellent results. In the case of the Doppler data, the technique can be applied with satisfactory results, even after a recent approach, which, in addition to a Doppler velocity test, com- bine all the available information concerning radar echoes.


The refractory chemical wastewater accounts for about 52% in the urban wastewater of Jiaojiang City,and is more difficult to be treated.By means of dynamic test,the modified two-phase process was found out and applied in engineering design.After operation for near two years,the process achieved good effect.The process has the advantages of flexible operation,higher buffer capacity,and higher removal rate of pollutants.The effluent quality basically reaches the standard under the large fluctuation of influent quality.


The aim of the present thesis was to examine the cognitive and language profile in children with poor reading comprehension using a longitudinal perspective. Even though comprehension skills are cl ...


Protein supplements have become a widespread practice amongst athletes and gym users worldwide. However, the use of protein supplements among female gym users in Saudi Arabia has not yet been investigated. The aim of this study was to investigate the prevalence of protein supplement usage among female gym users and their attitudes towards protein supplementation in Riyadh, Saudi Arabia In this cross-sectional study, 502 female gym users aged ≥18 years completed a structured, self-administered online questionnaire on the usage of protein supplementation. Socio-demographic information, anthropometry, health status, exercise frequency, attitudes, and knowledge regarding protein supplements were obtained. Statistical analysis was performed using SPSS 23. Independent t-test was used to check mean differences for continuous variables. Pearson's chi-square tests were used to identify associations between protein supplement use and categorical variables. The overall prevalence rate of protein supplement use among the study respondents was 36.3%. There were positive associations between the use of protein supplements and educational level (p < 0.05), the duration of being a gym member (p < 0.05) and frequency of gym visits per week (p < 0.05). Whey protein was the predominantly used supplement (57.8%) and the reason attributed to the use of protein supplement was muscle building (53.9%). The main sources of information regarding protein supplement use included the internet (30.2%) followed by gym coaches (25.3%). Our findings demonstrated that approximately third of females exercising in gyms use protein supplements, and most rely on internet sources for decision-making of protein supplements use. Nutritional education and consultations regarding protein supplement use are warranted.


The invention discloses a rocket launching system with water spraying, cooling and denoising functions. The rocket launching system comprises a multifunctional service tower, a movable launching platform and a guide groove. The multifunctional service tower is disposed on the movable launching platform. The guide groove is formed below the movable launching platform. A high-position water storage tank is disposed at the top of the multifunctional service tower. A water supply main pipe is arranged in the multifunctional service tower along the same. The top end of the water supply main pipe is connected to the bottom of the high-position water storage tank. An on-tower water spraying nozzle array is disposed on the multifunctional service tower. An on-platform water spraying nozzle array is disposed on the movable launching platform. A water spraying nozzle array is disposed at the inlet of the guide groove and in the guide groove. The rocket launching system has the advantages that gas flow cooling heat protection can be performed on the launching platform, launching gas flow noise can be constrained, the launching safety of carrier rockets is increased, and launching environments are improved.


The author gives a brief estimation of the standard of teaching in the times of A. Gerd, finding it very low. Wordy-dogmatic methods of teaching predominating then did not satisfy the pedagogue and he insisted upon organizing the process of teaching in such a way that pupils master the matter actively, carrying out some kind of independent investigations. The author analyses those works by A. Gerd in which the pedagogue gives methodical references on the developing of independence of pupils as well as on the carrying out of experiments, observations, excursions and practical work during the lessons of natural sciences in primary school. On the ground of the analysed works the author states that the initiator of the works dealing with independent investigations of pupils in the czarist Russia was A. Gerd. The article also deals with the appreciation of the works by A. Gerd.


Based on referring to plenty of references related to the electromagnetic shielding composites,the concept and connotation of conductive and magnetic shielding composites are given and the requirement causes of this kind of electromagnetic shielding composites applied in military and civil fields are analyzed.The questions existing in electromagnetic shielding materials are given and the current status of research on electromagnetic shielding materials is analyzed by associating with the conductive shielding materials,the magnetic shielding materials and the conductive and magnetic shielding composites.The microstructure design of conductive and magnetic shielding composites network-based and its feasibility analysis are presented at last according to the authors′ investigation.