Objective To approach the effect of blocking the JAK-STAT signal pathway in the treatment of rat's rheumatoid arthritis.Methods Thirty-six arthritis rat models,which had arthritis index more than 2 scores,were built successfully by Department of Rheumatology and Immunology,the First Affiliated Hospital of China Medical University,and they were divided into model group one and two,low dose of AG490 group,middle dose of AG490 group,high dose of AG490 group and leflunomide group.Besides,6 rats were treated as normal control group.And they were given normal sodium 1 mL,AG490 1、5、10 mg/(kg·d)and leflunomide 10 mg/(kg·d) by intraperitoneal injection or intragastric administration,then all the rats were sacrificed after 44 days.After that,compared the weight,arthritis index,the volume of toe,pathological score,and the change of p-STAT1,p-STAT3.Results The arthritis of model group developed rapidly,and the arthritis index,the volume of toe increased obviously,and the expression of p-STAT1 and p-STAT3 increased and the body weight decreased,all of which had significant meaning compared with that of control group.The body weights of rats in low dose group of AG490 were heavier than that of control group,the symptom of arthrocele in low dose group of AG490 was lighter than that of control group,and could inhibited the activation of JAK-STAT signal pathway in some degree,but the arthritis index numbers and the pathological score had no significant difference from that of model group.The body weights,arthritis index,the volume of toe and pathological score in middle dose group of AG490 improved obviously(P0.05).The therapeutic effect of AG490 was correspondent with that of leflunomide,and could also inhibit the activation of the signal pathway.Moreover,the high dose group of AG490 exerted effect earlier and the improving extent of pathological score was better than that of leflunomide group.Conclusion AG490 is the special blocking agent of JAK,which can inhibit the excess activating of STAT and lighten the symptom of rats' arthritis as well as decreased the pathological lesion of tissue and the therapeutic effect shows dose dependent.


The decomposition of any most degenerate unitary irreducible representation (single‐valued of discrete principal series) of an arbitrary noncompact rotation group SO0(p, q) (p ≥ q > 1) when restricted to the unitary irreducible representations of its maximal noncompact rotation subgroup SO0(p, q − 1) or SO0(p − 1, q) is derived, and characteristic features of the decomposition are discussed.


My concern is to understand how it is that contemplation of the past— better, of this or that preferred past—evokes in some people an impression which is distinctively weird. It is unmistakable; and anyone who has felt it will soon know what I am talking about. What is the impression, and whence the impressionability? To help identify my concern (and make it seem less eccentric) I shall let it emerge from some highly selective remarks about an issue in philosophy of history which is, by contrast, familiar and respectable: the debate between constructionists and realists. We cannot conceivably have direct acquaintance with, direct access to, the past; by their very nature, past events are over and done with and so unavailable for inspection. This much both camps agree on. However, they differ massively over what follows from this truth. For the constructionist concludes that what he calls the 'real past', what actually happened, can play no part whatsoever in historical thought. It is necessarily hidden, and we can have no inkling of it. What, and all, the historian can sensibly claim to know is the 'historical past', something which is constituted by and exists only in relation to his thought. Against this, the realist maintains that of course historians do not, necessarily or even typically, constitute the past; rather, they construct accounts of it which will be true if they conform to it as it actually was and false if they do not. And he charges his opponent with a number of fundamental confusions: mistaking accounts of historical events for the events themselves, confusing epistemological matters with ontological, and worst of all equating knowledge with direct perceptual awareness. Now, the realist is, in basics at least, fairly obviously right. And his criticisms are reinforced when we note that constructionists tend to combine with their vision of the impenetrability of the 'real' past the thesis that we undoubtedly know that there is a real past, with real people and real events. However, this piece of knowledge must for him, like that of an intelligible world for Kant, ever remain contentless, 'factually vacuous'.


Two new species in the new genus Stellulathyas, S. magnifica and S. lundbladi, and one in a previously named genus, Paramideopsis regalis are described from New Zealand. The species of Stellulathyas were collected in terrestrial situations. The anomalous zoogeographic distributions of these two genera are discussed.


In this paper, we introduce new types of Finsler metrics, called (α1 ,α 2)- metrics. We define the notion of the good datum of a homogeneous (α1 ,α 2)-metric and use that to study the geometric properties. In particular, we give a formula for the S-curvature and deduce a condition for the S-curvature to be vanishing identically. Moreover, we consider the restrictive Clifford-Wolf homogeneity of left invariant (α1 ,α 2)-metrics on compact connected simple Lie groups. We prove that, in some special cases, a restrictively Clifford-Wolf homogeneous (α1 ,α 2)-metric must be Riemannian. An unexpected interesting observation contained in the proof reveals the fact that S-curvature may play an important role in the study of Clifford-Wolf homogeneity in Finsler geometry.


In order to improve the teaching quality of aquaculture technology profession.After a few years of teaching and practice of reform,we adhere to the employment-oriented and deepen educational reform,and give priority practice teaching,and strengthen skills training,comprehensive training and aquaculture applications of highly skilled personnel so that the overall quality of graduates and skill levels improved significantly,particularly in the practice of manipulative ability and resolve practical issues in the technical aspects of showing obvious advantages,industry systems by employing units widely welcomed.


The European corn borer, Pyrausta nubilalis Hubn., was discovered near Boston, Mass., in 1917 and in the Lake Erie region in 1919. In 1922, an area of 5,836 square miles was known to be infested in the Lake region. In 1926 this had increased to 68,380 square miles. Intensity of infestation had increased to alarming numbers in 1926.

The International Corn Borer Committee was appointed in 1926. Ten million dollars ($10,000,000) were appropriated by the 69th Congress to carry out the 1927 spring clean-up campaign. Direction of the work centered in the Bureau of Entomology field headquarters at Toledo, Ohio.

The "clean-up" area comprised 2,500,000 acres of corn land. The funds were available March 14, and actual field work started March 21. The work was placed largely in the hands of the United States Department of Agriculture by the States.

Government equipment was used on 170,000 acres, of which 68,000 acres were treated under compulsory regulations; 202,338 farms were visited on which there were 2,505,005 acres of corn; 185,000 farms satisfactorily passed inspection and received the extra labor fee; 4,000 field and road units were used in the work and over an area of 35,000 square miles as many as 7,000 men were employed at one time.


Measurements of the transverse and longitudinal beam losses during a Tevatron store will be presented. The measurements utilize scintillation counters to monitor the nuclear interactions of the 1 TeV halo particles with a scraper that is located near the beam. If the particles are in time with the primary bunches, they are assumed to come from transverse perturbations inducing large betatron oscillations. Particles lost longitudinally drift around the ring due to synchrotron radiation and become asynchronous with respect to the bunches. A pulsed electron lens is then used to induce large betatron oscillations that extract these particles onto the scraper. The resulting nuclear interactions in the scraper are recorded by a gated scintillating counter system. The counting rates from the two channels provide an online measurement of the two types of beam loss. Known beam loss due to interactions at the IP and to nuclear collisions in the residual gas can be subtracted which then exposes the underlying losses from longitudinal and transverse instabilities.


The software of SolidWorks and GearTrax were used to model a simplified Worm Wheel-worm,and the virtual assembly was accomplished according to geometry size.The intervene of the component parts was checked,the movement state was analyzed by simulating Worm Wheel-worm based on Cosmosmotion.It is proved that the method that set up a 3D model of Worm Wheel-worm by using the software of SolidWorks and GearTrax can enhance the work efficiency,the reasonable of the mechanism design was verified that motion characteristics were consistent with the theoretical analysis.


A signal output apparatus and an image forming apparatus, comprising: a vibration applying portion for contact with the sheet, the vibration applied thereto; detecting unit, the vibration output signal. A sheet type determining apparatus, comprising: a vibration applying portion for contact with the sheet, the vibration applied thereto; detecting unit, based on the vibration output signal, and in accordance with the output signal of the detection unit determines the type of the sheet. A method for determining the type of sheet, comprising: a contact with the sheet, a first step of applying vibration thereof; and based on the signal, the kind of sheet is determined in the third step; step from the second detecting unit, the output signal.


HPLC was used to establish the fingerprint of Chelidonium majus L.It was carried out on Diamonsil C-18 column and eluted gradient with acetonitrile-0.01 M potassium dihydrogen phosphate at a flow rate of 1 ml/min,column temperature was 35 ℃.The detection wavelength was 290 nm.Under the condition,the constituents of Chelidonium majus L.were good separated.the chromatogram we got can be used as the fingerprint of Chelidonium majus L.


Two methods for the connection of signalling units to digital switching networks are presented. The proposed methods make it possible to connect singalling units without affecting the traffic characteristics of networks.


This one-year project focused on the effects on fuel economy, emission characteristics, driveability, and component compatibility of in-use light duty vehicles running on blends of 30% and 10% ethanol. The test sample included 15 vehicles of various years, makes, and models. The procedures used for testing each of the fuels' mileage, emissions, driveability, oil analysis, and material compatibility are described. E10 fuel contains 90% gasoline and 10% ethanol by volume. E30 contains 70% gasoline and 30% ethanol by volume. These were the two fuels used in this test. The results of the study revealed that volumetric fuel economy decreased when using E30. There were no driveability or material compatibility problems experienced during the study. Emissions results showed that some emissions were higher when running on E30, some were lower. All emissions were low and well below federal standards.


The integration of disability issues in education and training programmes has recently been a focus of attention for governments, organizations and institutions in the world. The aim of the study was to establish the extent to which disability issues have been integrated in TEVET institutions in Lusaka province in Zambia.  Both qualitative and quantitative research methods were used. The researchers visited 23 sites in Lusaka province and collected data using questionnaires, interview guides and focus group discussion schedules from 250 participants.  Participants were principals, heads of departments, lecturers and instructors; managers and employers; disabled and abled students drawn from the Technical Education, Vocational and Entrepreneurship Training (TEVET) institutions within the province. Simple random sampling and purposive sampling techniques were applied. Findings reveal that the majority of the participants were in favour of integrating disability issues into the vocational and entrepreneurship training programmes in TEVET institutions. More abled students were enrolled in TEVET institutions than the disabled. Participants expressed ignorance on the existence of the TEVET National policy on the integration of disability issues in TEVET institutions. The training environment and programmes seemed to be suitable for students with mild than those with severe disabilities. Based on the findings, the study recommends that Technical Education,Vocational and Entrepreneurship Authority (TEVETA) in conjunction with other stakeholders, facilitate a national situational analysis. This analysis should focus on the integration of disability issues in TEVET institutions in order to get a national picture of the extent to which disability issues have been integrated in institutions. This should apply in both rural and urban provinces of Zambia for generating more detailed and useful information for national planning on integration of disability issues in training programmes.Â


ABSTRACTAim: To assess ethical issues in everyday clinical practiceamong physicians and nurses of the University HospitalRijeka, Rijeka, Croatia.Subjects and methods: We surveyed the entirepopulation of internal medicine, oncology and intensivecare specialists and associated nurses employed at theUniversity Hospital Rijeka, Rijeka, Croatia (n=532). Ananonymous questionnaire was used to explore the typeand frequency of ethical dilemmas, rank of their difficulty,access to and use of ethics support services, training inethics and confidence about knowledge in ethics.Physicians (n=113, 55% of them female) ranged in agefrom 27 to 61 years, and nurses (n=251, 95% female),from 20 to 52.Results: The most frequent ethical dilemmas concerneduncertain or impaired decision-making capacity (66% ofphysicians, 47% of nurses, p=0.008), limitation oftreatment at the end of life (60% of physicians, 31% ofnurses, p,0.001) and disagreements among familymembers (47% of physicians, 31% of nurses, p=0.025).The most difficult dilemmas concerned euthanasia andphysician-assisted suicide (49% of physicians, 52% ofnurses) and limitation of treatment at the end of life (14%of physicians, 18% of nurses). Only a minority reportedever using any kind of ethics support services (12% ofphysicians, 3% of nurses, p=0.001) or being veryconfident about knowledge in ethics (5% of physicians,6% of nurses).Conclusions: Similar ethical difficulties are present in theclinical practice of both physicians and nurses, withimportant differences in access and use of ethics supportservices. A need for systematic ethics educationalactivities was identified. Inclusion of individual ethicsconsultants in Croatian healthcare ethics support servicesis strongly advised.Morally challenging situations routinely arise inclinical settings.


........................................................................................................4 Introduction: An Exploration of Early Nineteenth Century Individualism............................6 Chapter One: The Founding and Early Years of Union College, 1775 – 1812.....................26 Chapter Two: The Emergence of Public Discourse at Union College, 1812 – 1837...............45 Chapter Three: Nott's Presidential Paternalism, Reform, and Student Reaction, 1817 – 1840...60 Conclusion.....................................................................................................80 Bibliography..................................................................................................84


The partial differential equations with singular coefficients are very important in the field of mathematics,however,the exact solution of these equations are very difficult to attain.In this paper,a class of semilinear parabolic problems with singularities is considered.Results of the weighted L2 norm estimation with solution are obtained.


Arora, Barak, Brunnermeier, and Ge showed that taking computational complexity into account, a dishonest seller could dramatically increase the lemon costs of a family of financial derivatives. We show that if the seller is required to construct derivatives of a certain form, then this phenomenon disappears. In particular, we define and construct pseudorandom derivative families, for which lemon placement only slightly affects the values of the derivatives. Our constructions use expander graphs.
 We study our derivatives in a more general setting than Arora et al. In particular, we analyze arbitrary tranches of the common collateralized debt obligations (CDOs) when the underlying assets can have significant dependencies.


Properties of Shor's algorithm and the related period-finding algorithm could serve as benchmarks for the operation of a quantum computer. Distinctive universal behaviour is expected for the probability for success of the period-finding algorithm as the input quantum register is increased through its critical size of $\mathfrak{m}_0=\lceil 2\log_2 r\rceil$ qubits (where $r$ is the period sought). Use of quadratic non-residues permits unequivocal predictions to be made about the outcome of the factoring algorithm.


Objective To study the impact of pH value on the binding of Cu(Ⅱ) with rabbit liver metallothionein(MT).Methods 0.2 ml 9.2×10-4 mol/L CuSO4 solution was added to 2 ml of rabbit liver zinc-metallothionein solution at pH values of 3,4,5,6 and 7 respectively.UV absorption spectrogram of Zn-MT solution and Cu(Ⅱ) binding Zn-MT solution were scaned at 200-300 nm.Copper(Ⅱ) binding with metallothionein was determined by inductively coupled plasma mass spectrometry(ICP-MS) method after removing the excess Cu2+ by semi-permeable membrane.Results The levels of copper(Ⅱ) binding with metallothionein increased with pH value increasing.Metallothionein binding copper(Ⅱ) content with the pH value declined at first,then increased,and copper(Ⅱ) content reached the lowest value at pH value of 5.Conclusion It is not conducive to copper binding metallothionein and the ability of copper binding metallothionein is weak when metallothionein released the protons as pH=5.Because of the different composition of metallothionein α-,β-domain,zinc and copper with metallothionein have different binding sites at different pH values,so the metal binding capacity is different.The zinc flaks off from the metallothionein at pH values of 3 and 4,then the copper content increases.


The most well-known acoustical parameters - including Reverberation Time, Early Decay Time, Clarity, and Lateral Fraction - are measured using data obtained from omnidirectional or figure-of-eight microphones, as specified in ISO 3382. Employing a multi-channel receiver in place of these conventional receivers can yield new spatial information about the acoustical qualities of rooms, as well as the potential for new parameters that could have greater predictive power in terms of listeners' subjective preferences. In this research, a spherical microphone array was used to measure the room impulse responses of a number of different concert and recital halls. The data was analyzed using spherical harmonic beamforming techniques, along with other direction of arrival estimation algorithms, to understand how the soundfield evolves spatially over time at different points in the room. The results were compared to geometrical acoustic simulations and used to differentiate between listener positions which exhibited similar values for the standard parameters. In addition, new parameters were examined, including soundfield homogeneity and other spatial ratios.


In this issue we present articles by Ceramics artist Angela Valamenesh who utilises imagery drawn from early scientific representations of microscopic life as research material in the development of her current body of work, CEO and artistic director of Craft Victoria, Joe Pascoe traces the beginnings of the organisation and shifts in thinking in the craft sector over the past four decades as Craft Victoria celebrates 40 years, Tina Lee discusses her arts practice and the works of her contemporaries who, over the last decade, have engaged in a nostalgic return to Australian studio and commercial ceramic traditions of the late nineteenth and twentieth century, Mags Webster writes about
Yiwarra Kuju - the Canning Stock Route project a joint initiative between arts and cultural body FORM, the National Museum and nine remote Aboriginal art centres and communities.


In this work, a system architecture is presented for a voltage-controlled crystal oscillator (VCXO) with integrated Pierce structure and varactors in a deep submicron CMOS process. To meet low crystal drive, wide pull range, and negative resistance specifications in a low power supply leads to Pierce VCXO designs requiring both amplitude and operating point regulation. In this design, an automatic amplitude control (AAC) loop and embedded replica bias are implemented with the Pierce cell to provide the required regulation.


We present a checklist comprising 39 species of the genus Scopula (Geometridae, Sterrhinae) from Korea by adding four new records. One species Scopula paraconfusa Kim & Choi spec. nov. is described as new and three species S. butleri, S. disclusaria and S. hypochra are recorded to the Korean fauna for the first time. We provided the diagnosis for four species and male and female genitalia, if available.


and basal Fungi in sediments. Our extensive and systematic sequencing of geographically sepa-rated sites provides the most comprehensive molecular description of coastal marine protist diversity to date.


The author analyzes the critical reception of the works by Justyna Bargielska, pondering over mechanisms of defense from over-interpretation or critical misuse included in the poet's books. Using the hypothesis of narrative sources in defense against accusation as a starting point, she researches Bargielska's writing strategies, especially in the novel Male lisy, in order to define the role of shame within. Bargielska's characters refuse to be ashamed of things, which are generally considered shameful. The purpose of this work is to indicate that this phenomenon – called the "shamelessness strategy" – influences the form of text itself; what it allows for, and what it makes a necessity.


I was recently watching television, and it struck me that the word innovation was used in 7 consecutive commercials. I spent the next half hour pondering, ''What is the common link between automobiles, haircuts, soda, airlines, hardwood flooring, and healthcare?'' and ''What do people mean when they say 'innovation'?'' Eventually, I came to the conclusion that TV commercials used innovation to convey a new idea that produces, adds, or enhances value or, in marketing language, to say ''the next great thing.'' In healthcare delivery organizations, we are uniquely challenged in that there is a real and defined need for innovation. Yes, there is a long history of innovative inventions, products, and discoveries in healthcare (ie, vaccines, medications, artificial organs, etc). But what happens when we need to innovate the structures and processes for how healthcare is delivered? The existing paradigms of care delivery have proven to be fiscally unsustainable and may not support the delivery of the safest, most effective, timely, patient-centered, equitable care. Thus, a comprehensive plan for the future must address cost reduction, but also fundamentally how care is provided. Large governing healthcare entities such as the Centers for Medicare & Medicaid Services and the American Nurses Credentialing Center's Magnet Recognition Program identify innovation as a key component of transforming healthcare. This has driven a growing need to quantify, articulate and replicate innovation ina tightly resourced,operational care delivery setting. The experiences from the Massachusetts General Hospital Innovation Unit Program (Program) provide a unique insight into innovation in a care delivery setting and specifically evaluation of innovation. The Program was developed as a frontline initiative to address the gaps in the continuum of care and utilize the expertise of all clinical disciplines to improve the patient experience, quality of care, staff satisfaction, and empowerment while decreasing redundancy, costs, length of stay, and readmission rates. The progress and successes of this trailblazing model are in response to current and future healthcare reform stem from interventions that span philosophy,practice, technologies, and roles and also include a thorough strategy to evaluate innovation interventions in an operational setting, essentially letting us know how we are doing rebuilding the ship while it is sailing. The initial, broad approach to data collection and evaluation of this complex innovation Program utilizes multiple measures including focus groups, surveys, observations, and analysis of quality and administrative data. As this expansive approach to data collection was planned, there was a conscious effort to also prepare to support specificity in inquiry as needed. The immense amount of data were valuable, but the how, when, and what was the emerging story that needed to be clearly articulated


Acute small bowel ischaemia is a mostly irreversible condition associated with high mortality. Here we report the case of a patient after severe abdominal trauma in whom the superior mesenteric vein (SMV) was completely occluded for more than 15 h in the absence of any collateral venous drainage. Following surgical reconstruction of the SMV and with scheduled relaparotomies for 5 days, the bowel showed slow recovery. Now the patient is well and on complete oral nutrition.


Insects rely on their highly efficient and precise olfactory systems to find suitable mates, host plants and oviposition sites, and adapt to the changing environment. The odorant receptors (ORs) including pheromone receptors (PRs) play a vital role in this process. While extensive studies have been focusing on deorphanization of lepidopteran PR genes, the information on the ligand profiles of general ORs is still sparse. In the present study, we identified a repertoire of 61 ORs including the co-receptor Orco from antennal and ovipositor transcriptomes of the turnip moth Agrotis segetum, which clustered in all the major lepidopteran OR clades. We characterized the function of eight female-biased expressed ORs in Xenopus oocytes and found three ORs differentially tuned to plant volatile compounds that might be repulsive or attractive to the moths. AsegOR13 was broadly tuned to a number of herbivore-induced plant volatiles (HIPVs) while AsegOR20 was specific to citral; AsegOR17 was narrowly tuned to the alcohols, isoamyl alcohol, pentanol and benzyl alcohol, that are potentially attractive to moths. The orthologues of the three ORs in other moth species seem to share the conserved function. Our results support the hypothesis that insects recognize their host plants mostly by detecting the mixture of ubiquitous compounds, instead of taxonomically characteristic host compounds. The combination of narrowly and broadly tuned ORs will ensure both the accuracy of the most important odor signals and the plasticity of the olfactory system to the changes in the environment.


prevent recurrent central line sepsis. J Infect 2004; 49: 20–22 5. Schwab SJ, Weiss MA, Rushton F et al.Multicenter clinical trial results with the LifeSite hemodialysis access system. Kidney Int 2002; 62: 1026–1033 6. Sissons CH, Wong L, Cutress TW. Inhibition by ethanol of the growth of biofilm and dispersed microcosm dental plaques. Arch Oral Biol 1996; 41: 27–34 7. Laird J, Soutar R, Butcher I. Complications of the ethanol-lock technique in the treatment of central venous catheter sepsis. J Infect 2005; 51: 338 8. Crnich CJ, Halfmann JA, Crone WC, Maki DG. The effects of prolonged ethanol exposure on the mechanical properties of polyurethane and silicone catheters used for intravascular access. Infect Control Hosp Epidemiol 2005; 26: 708–714


The total DNA was isolated from lymphocyte of peripheral blood of cattle. The PRNP gene was amplified by PCR method. The cloned PRNP gene was 795 nucleotides long and contains the entire PRNP coding sequence which has no intron and has 99% homology with the published gene sequence. And the deduced protein contain 264 amino acids, which had a calculated molecular weight (MW) of 34.0 ku. It is the first time the new alleles,Q264Q and G360A were found in the coding region of PRNP.


A preliminary study has shown that the addition of 15% (v/v) coconut water (CW) to the culture medium significantly improved callus growth, shoot-regenerative capacity, and shoot growth in leaf disk cultures of spinach (Spinach oleracea L.). Subsequently, the influence of a range of CW concentrations, 0%, 5%, 10%, 15%, or 20% (v/v), was examined. Callus weight obtained after 5 weeks showed direct relationship to the concentration of CW (...)


Channel modeling is the basis for the design of wireless communication systems. In order to design intelligence transportation systems, it is necessary to conduct in-depth research on the internet of vehicles channels. First, we summarize the characteristics of the vehicle to everything(V2X) standardized channels. Second, we discuss the influence of antenna settings, non-stationary characteristics and mm-wave on the vehicle to vehicle(V2V) channels. Third, we describe the V2V channel parameters and analyze the advantages and disadvantages of 3 modeling methods of it. Finally, we propose the work to be done in the future.


1. A therapeutic or prophylactic agent for tumors decay syndrome comprising as active ingredient 2-feniltiazolnoe compound represented by the following formula (I): wherein: R C-Calkoksigruppu, morpholino group, 4-methyl-piperazin-1-yl group or a piperidino group; R a nitro group or a cyano group; X represents a carboxyl group or C-Salkoksikarbonilnuyu group; and Y represents a hydrogen atom or C-alkyl group, or a pharmaceutically acceptable sol.2. A therapeutic or preventive agent according to Claim. 1, where tumor lysis syndrome is a syndrome in a patient with high riskom.3. A therapeutic or preventive agent according to Claim. 1, where tumor lysis syndrome is a syndrome in a patient with intermediate riskom.4. A therapeutic or preventive agent according to Claim. 1, where tumor lysis syndrome is a syndrome in a patient with low riskom.5. A therapeutic or prophylactic agent according to any one of claims. 1-4, where the tumor lysis syndrome include hyperuricemia caused by chemotherapy or radiotherapy for malignant opuholi.6. A therapeutic or prophylactic agent according to any one of claims. 1-4, where the tumor lysis syndrome is a syndrome that is observed not being caused by antineoplastic therapy in which hyperuricemia occurs and lowered function pochek.7. A therapeutic or prophylactic agent according to any one of claims. 1-4, where the tumor lysis syndrome is a syndrome when giperurikemiyaprisutstvuet prior anticancer terapii.8. A therapeutic or prophylactic agent according to claim. 7, where tumor lysis syndrome is a syndrome in case


Massive Open Online Courses (MOOCs) have proved to be revolutionary in the development and widespread of educational technology over the past few years. It has been identified that these systems, despite all the benefits, lack interaction and collaboration around learning materials. This paper explores how to leverage learning channels to support interaction and collaboration in MOOC environments. We present the design, implementation, and evaluation details of learning channels in CourseMapper, a MOOC platform which supports collaboration and interaction around learning materials using collaborative Pdf and video annotations. More specifically, we report on the application and results of a human-centered design (HCD) approach used to systematically design learning channels. Three design iterations with five new users in each iteration (N=15) were conducted from an initial user interview to the final design. After the development, user experience with the system was evaluated with end users (N=10) based on the Technology Acceptance Model (TAM). The evaluation results show that the introduction of learning channels provides a valuable mechanism to support effective interaction and collaboration in a MOOC environment.


A nim als have always been used to represent cer-tain hum an characteristics.Countries also use anim alsas sym bols.From eagles to lions,m any countries usean anim al to show its national spirit and character.1.U S:T he bald eagleThe im age of an eagle is on the U SPresident's flag,and on the one-dollarbill.The bald eagle is a large,pow erful,brow n bird with a white head and tail.The term"bald"does not m ean that thisbird lacks feathers.Instead,it com es fromthe old word piebald,that m eans,"m arked w ith ...


Introduction -Michael Walzer LESSONS FROM THE PAST 1. No Exit but Victory: Britain and the American Colonies -Stanley Weintraub 2. America and the Philippines: The Graceful Withdrawal -Stanley Karnow 3. India and Britain: The Consequences of Leaving Too Soon -Rajeev Bhargava 4. The Surprising Success: The United States and Korea -Fred Smoler 5. France and Algeria: Claim Victory and Au Revoir -Todd Shepard 6. Vietnam and the United States: The Price of Intransigence -Frances FitzGerald 7. The Gates of Gaza and the Limits of Power: Israel and Gaza -Shlomo Avineri GETTING IN/GETTING OUT 8. 9/11 and the Road to Iraq -Nicolaus Mills 9. The Persistence of Empire -David Bromwich 10. Departing Responsibly -Brendan O'Leary 11. It Isn't Over -George Packer List of Contributors Index Acknowledgments


IN 1939, MOORE (1) POINTED out that consistent modifications in body growth had not been demonstrated for mammals as an effect of castration. This is particularly evident in studies concerned with skeletal changes following ablation of the testis. Hatai (2) found that in rats killed 120 to 170 days after castration the femur, tibio-fibula, humerus and radiO-ulna tended to be very slightly longer than in corresponding controls. Lawless (3) castrated young rats and killed them after intervals of 65 to 86 days. He reports that in the castrates the femur had grown slightly less, while the growth of the humerus was not significantly altered. Rubinstein and his collaborators (4) found that the skeleton of rats killed 58 days after castration not only failed to become larger but was actually significantly inhibited in its growth.


The 2001 Gujarat earthquake was one of the most destructive intraplate earthquakes ever recorded. It had a moment magnitude of M w 7.6 and had a maximum felt intensity of X on the Modified Mercalli Intensity scale. No strong ground motion records are available for this earthquake, barring PGA values recorded on structural response recorders at thirteen sites. In this paper, synthetic ground motions are generated at surface level using the stochastic finite-fault method. Available PGA data from thirteen stations are used to validate the synthetic ground motions. The validated methodology is extended to various sites in Gujarat. Response spectra of synthetic ground motions are compared with the prescribed spectra based on the seismic zonation given in the Indian seismic code of practice. Ground motion characteristics such as peak ground acceleration, peak ground velocity, frequency content, significant duration, and energy content of the ground motions are analyzed. Response spectra of ground motions for towns situated in the highest zone, seismic zone 5, exceeded the prescribed spectral acceleration of 0.9 g for the maximum considered earthquake. The response spectra for towns in seismic zone 5 exhibit peaks in the low period ranges, indicating high vulnerability of low rise structures designed as per the provisions of the Indian seismic code of practice. The response spectra for towns situated in seismic zone 3 were considerably lower than the prescribed maximum spectral acceleration of 0.4 g. The substantial damage reported in towns situated in seismic zone 3 is due to poor construction practices and non-compliance with provisions of seismic design standards.


The characteristics of initial combustion in gun chamber concerning the surface treated azidonitramine propellants with desensitizing and coating were studied by means of experiments. The results show that the initial combustion performance of the surface treated is improved. The results also show the differences of influence between two kinds of surface treating on the initial combustion.


Specimens of centuries-old Vitis vinifera L. cv. Albarino were collected in 1987 throughout Galicia, Spain. Eight of these uncertified clones were planted in a homogeneous plot and characterized by ampelographic traits and DNA-based molecular markers in order to identify their agronomic variability. Clone CSIC-3 had the largest grape clusters, the highest must yield per berry, the highest alcohol potential, and relatively low total must acidity. CSIC-2 had the highest total must acidity. CSIC-9 had the largest grape clusters.


Part I describes a theory of antibody-antigen reactions
employing bivalent and univalent antibody molecules
and multivalent antigen molecules. All species in a system
of this kind are defined by a distribution function which
has been derived on the basis that the most probable distribution
is the appropriate one. Some of the features of
antibody-antigen reactions are discussed in the light of
this theory. In Part II experiments are described which measured
the increase in turbidity of an antibody-antigen system
with increasing time of reaction. It was found that the
rate of aggregation of antibody and antigen molecules
into large aggregates is dependent on the composition
of the system. The existence of soluble aggregates in
the antigen excess region is indicated. A general theory of Rayleigh scattering due to
composition fluctuations in multi-component systems has
been developed with the aid of the grand canonical ensemble
of Gibbs. It is found in Part III. The equation
developed contains previously neglected terms arising
from thermodynamic interactions between solutes in systems
of more than two components.


The present study attempts to make an interdisciplinary approach to issues of associating motherhood and family with work and employment. Thus, in the perspective of discussing the specific theoretical construct in the context of social sciences and through the interplay of History, Literature, Sociology, Politics and Economics, the study examines women's status, which, in the history of Western thought, is defined, in social, economic, political and cultural terms, within the framework of a production reproduction system. Remarkably, the crucial issue of ideology or, as Beauvoir posits, of the religion of motherhood, in historic, social and economic terms, has always been associated with a policy of priorities concerning birthrate and family, which are considered fundamental factors for the development of the social fabric. It is demonstrated that the relationship of childbearing and childrearing, work and motherhood has been a recurring issue not only in the social scene, but also within feminist movements in Europe and America, depending on historical, political and economic conditions. This is a common economic, political and cultural context in social history, impregnated with patriarchal principles, and generating the glass ceiling effect, namely, barriers and disparities impeding women to rise to the upper rungs of the corporate ladder. Thus, in the name of deified motherhood, women have constantly been deprived of the possibility of pursuing career advancement or intellectual achievement on account of being forced to bear children. The specific premise has been variously reflected in literature since the time of Rousseau, Darwin and Freud, demonstrating that, in interrelation to work and employment, spirituality and idealization, motherhood ideology has still remained, in social and scientific terms, an open question.


This paper considered heterogeneous multi-anticipative car-following modeling established by estimating car-following models using empirical trajectory data. Based on the estimation results, the authors conclude that including multi-anticipative behavior strongly improves the descriptive performance of car-following models at the microscopic level. Furthermore, the papers has shown that the behavior of the individual drivers can only be captured by considering different car-following modeling paradigms, in this case the generalized Helly model family and the modified Lenz model family. Finally, it was concluded that the inter-driver differences were not only expressed by the suitability of different model types, but also by the large variability in the driver-specific car-following parameters. Based on the result, the authors proposed a HEterogeneous Multi-Anticipative (HEMA) model that includes the generalized Helly mode and the modified Lenz model.


Two electromagnetic scattering problems for irregular imperfectly conducting structures are considered. The first one is harmonic dipole field scattering on a bicone at which approximate boundary conditions are fulfilled. The bicone consists of two infinite cones with different surface properties (resistive shells) those depend on distance from vertexes. The other problem is devoted to studying electromagnetic scattering on 3D System of plane angular resistive sectors. Analytical and numerical solutions are obtained. Effects of resistivity are analyzed.


fixture (1), knee coil (2), specimen (3), tibia fixture (4), rope to apply load (5), pneumatic cylinder (6) Determination of the meniscal deformation under compressive loading through MR-imaging Maren Freutel, Fabio Galbusera, Andreas Seitz, Axel Bornstedt, Volker Rasche, and Lutz Dürselen Institute of Orthopaedic Research and Biomechanics, Ulm, BW, Germany, Department of Internal Medicine II, University Hospital of Ulm, Ulm, BW, Germany


Nervous system teaching materials available in schools do not contain scientific-related content as mandated by the 2013 curriculum. In addition, teaching materials also do not contain student character reinforcement content. The purpose of this study is to develop "Nervous Problem Based Module with a  Conservation Character" as a nervous system learning supplement. This type of research is Research and Development (R&D) using ten steps, namely identification of potential and problems, data collection, product design, product design validation, product design revisions, small scale trials, product revision I, large scale trials, product revision II, and final products. The research subjects were students of class XI of SMA N 1 Bae Kudus. Nervous Problem Based Module with a  Conservation Character  tested the feasibility, readability, and effectiveness. Feasibility tests obtained very valid results. Readability test results were very valid. Test effectiveness by applying  Nervous Problem Based Module with a  Conservation Character in learning, obtained effective results and can be used in learning. The insertion of the conservation character reinforcement in the module gives positive results on the character of students. It can be concluded that "Nervous Problem Based Module with a Conservation Character" is decent and effectively applied in the nervous system learning.


This paper is concerned with Hopf bifurcation analysis for a two prey one predator system with time delay. The state feedback and parameter perturbation are used to delay the onset of Hopf bifurcation or make the bifurcation disappear. The sufficient conditions for the local stability and existence of local Hopf bifurcation of the system are obtained. In particular, special attention is paid to the direction of Hopf bifurcation and the stability of the bifurcated periodic solutions. Finally, some numerical simulations are presented to show that the hybrid controller is efficient in controlling Hopf bifurcation.


Low cost capital improvement techniques can be used to improve the efficiency of surface transportation systems as demonstrated in New York City. A project was undertaken to improve air quality in midtown Manhattan by redesigning vehicle usage and promoting transit. To assist in the evaluation of Midtown's surface transportation system, a conceptual model was developed with modal, operational and physical elements. All aspects of the movement of persons and vehicles were investigated and an overall circulation plan was developed. A number of projects were selected for demonstration to indicate the effectiveness of the various strategies in improving the efficiency of the transit system.


The present work is to analyze the effect of auxins and cytokinins to develop a standard protocol for in vitro propagation of Ionidium suffruticosum Ging. Hormones like 2, 4-D, NAA, IBA, IAA, Kinetin, BAP and Zeatin were used in different combinations and concentrations for callogenesis and indirect plant regeneration. The rapid and maximum callus formation was achieved from leaf explant on MS medium supplemented with 2, 4-D (0.5mg/L). MS with 2,4-D (0.5mg/L) was a prompted media to maintain the leaf callus for a long duration and to possess highly regenerative potential referred to as "stock callus". Different hormonal combinations often caused the transformation of the calli from soft crystalloid and translucent to compact, hard, yellowish and greenish forms. Maximum (95%) and highest number (40.67/explant) of multiple shoots were obtained from leaf callus in MS media containing Kinetin (4.0mg/L). Among the auxins and cytokinins used the maximum (62%) root formation in the shoots of leaf derived callus was achieved on the MS medium supplemented with NAA (2.0mg/L) and kinetin (0.2mg/L). However, the thick and longest roots (6.3cms) from shoot lets were obtained on MS medium with Kinetin (4.0mg/L). Seventy percent of the rooted plantlets were survived and successfully acclimatized in soil.


The geometric calibration of the photogrammetric airborne sensor is an important part in photogrammetry. In order to validate and improve the geometric accuracy of ADS40 which is a kind of three-tine-scanner photogrammetric airborne sensor, a geometric calibration method is developed in this paper using a test field. According to ADS40, schemes and theories of the geometric calibration method are introduced, a calibration model which is based on self-calibration bundle adjustment is proposed. The effects of factors, such as flight strip arrangement, amount of ground control point, and additional parameters of the calibration model and so on, influencing the accuracy of ADS40 are analyzed through experiments. Consequently, experimental results showed that the self-calibration model can highly improve the geometric accuracy of ADS40. Moreover, a GCPs-based method is proposed in this paper to correct the interior parameters and the CCD cell coordinates in the focal plate of the ADS40, and is proved feasible through experiments.


This essay calls for a reorientation in scholarly approaches to civic engagement from asking questions of what to asking questions of how. I advance a discourse theory of citizenship as a mode of public engagement. Attending to modalities of citizenship recognizes its fluid and quotidian enactment and considers action that is purposeful, potentially uncontrollable and unruly, multiple, and supportive of radical but achievable democratic practices. Citizenship engagement may be approached through potential foci of generativity, risk, commitment, creativity, and sociability. A discourse theory reformulates the relationship between citizenship and citizen, reveals differences in enactments of citizenship, and calls attention to hybrid cases of citizenship.


The developmental background and advantages of an assembled camshaft are discussed. The different joining methods and their strongpoints and shortcomings are analyzed. The manufacturing technique, application range, production status and development trends of the assembled camshaft are introduced.


The Colombian Constitution of 1991 and the Statutory Law on Religious Freedom (1994) constitute the first and foremost benchmark with respect to treatment of the religious factor under civil law. Development of the principles of religious freedom, secularism, equality and cooperation has affected the legal regime applicable to churches and their organizations. It created a new legal status for churches and denominations, and their respective registration, with the possibility of entering into agreements or pacts with the Colombian state under public law. At the same time, the specific recognition afforded to the Catholic Church and its organizations under the Concordat with the Holy See (1973) continues. The different possibilities with respect to legal form could raise concerns about the principle of equality, particularly with respect to the meaning and scope of the various forms of personification provided for under the law and its instrumental nature in serving religious freedom. The objective is to overcome formalist visions and to underscore the balance that should exist between social reality, original legality (human rights) and legal-positive formalization, taking into account the experiences of other countries. Some possible changes in the Statutory Law on Religious Freedom are suggested.


A compact CPW fed rhombus shaped slot triangular patch antenna is proposed and analyzed. The radiating structure consists of a rectangular patch with a rhombus shaped slot to reduce the overall dimensions. The antenna is designed on FR4 substrate and characterized by measuring return loss, VSWR, gain and radiation pattern. The proposed antenna is configured with coplanar waveguide (CPW) feed and is suitable for WLAN applications. The model is analyzed for different substrate thicknesses using Finite Element Method based Ansoft High Frequency Structure


Background and Objectives :N egative symptoms emerge in many patients with psychotic disorders long before the onset of the acute illness. These symptoms are often impossible to differentiate from certain Cluster A personality traits. Methods: The current study examines the extent to which premorbid negative symp- toms are contributing factors to the development of primary and secondary negative symp- tomatology. Participants were 84 neuroleptic-naive patients experiencing the occurrence of their first acute psychotic episode. Symptoms of psychopathology were assessed at two points: at admission and after remission of the acute episode. The Spanish version of the PANSS scale was administered. Premorbid personality assessment was considered as a proxy measure to evaluate each participant's negative symptomatology prior to the onset of the illness. Potential causes of secondary negative symptomatology, such as depression and extrapyramidal symptoms, were also examined. Results: 'Non-respondent' or 'residual' negative symptoms at discharge were signifi- cantly predicted by primary negative symptoms. To a lesser extent, disorganization and depressive symptoms at discharge and the Schizoid dimension of premorbid personality predicted residual negative symptoms. Conclusions: The severity of negative symptoms at the onset of the psychotic episode varied across patients. After controlling for 'respondent' and 'non-respondent' primary negative symptoms and other potential causes of negative symptoms, premorbid negative symptoms had a slight, but significant predictive relationship with residual negative symptoms.


Abstract Flame atomic absorption spectrometry (FAAS) is one of the most widespread traditional analytical techniques for trace element determination, but it often suffers from poor sensitivity due to the low nebulization efficiency and the short residence time of free atoms in the flame. On the basis of conventional FAAS, flame furnace atomic absorption spectrometry (FF-AAS) is developed with a tube (flame furnace) placed on top of the FAAS burner for the atomization. Sample is introduced via beam injection (BIFF-AAS) or thermospray (TS-FF-AAS). Due to the total sample introduction and prolonged residence time of free atoms in the flame furnace, marked sensitivity improvement is obtained for volatile and semivolatile elements over conventional FAAS. TS-FF-AAS can be employed as an element-selective detector for GC, HPLC, or CE for studying of metal speciation analysis and metallomics. In addition, three newly developed sample introduction methods, including ultrasonic nebulization, hydride generation, and pneumatic nebulization, are discussed. The analytical figures of merit and practical applications of FF-AAS in analytical atomic spectrometry are reviewed in this article.


This experiment was conducted to investigate the effects of sodium butyrate and weanling days on growth performance and digestive enzyme activity in the intestine of weanling piglets.Ninety-six healthy 21-day-old weanling Duroc×Landrace ×Yorkshire piglets with initial weight of (6.00 ±0.05) kg were randomly divided into 3 groups:control group,trial group 1 and trial group 2.There were 4 replicates of 8 pigs in every replicate.The levels of dietary sodium butyrate supplementation were 0,1 and 2 g/kg.On day 3,7 and 14 after weanling,one piglet from one replicate was slaughtered,respectively. The results showed that,on day 3,7 and 14 after weanling,ADG in trial group 1 increased by 5.0% (P0.05), 13.4% (P0.05) and 2.3% (P0.05),respectively compared with control group.Average daily enzyme activity from day 1 to 14 after weanling:total protease activity of proximal jejunum,distal jejunum and ileum in group 1 and group 2 were higher than those in control group;amylase activity of duodenum in group 1 and group 2 were 28.5% (P0.05) and 6.4% (P0.05) higher than those in control group,respectively;compared with control group,amylase activity of proximal jejunum in group 1 and group 2 were increased by 5.9% (P0.05) and 10.5% (P0.05),respectively;amylase activity of ileum in group 1 and group 2 were 21.5% (P0.05) and 22.1% (P0.05) higher than those in control group,respectively. Sodium butyrate concentration significantly affected lipase activity of duodenum and proximal jejunum (P0.05).Weanling days significantly affected amylase activity in duodenum and proximal jejunum of piglets and lipase activity in every intestinal tract of piglets (P0.05),and had significantly effects on total protease activity in distal jejunum (P=0.001).In conclusion, growth performance and digestive enzyme activity in the intestine of piglets were increased by 1 g/kg dietary sodium butyrate supplementation.Lipase activity in intestinal tract of weanling piglets was significantly affected by weanling days (P0.05).


In this paper, a novel nine level bi-direction multilevel inverter is proposed, The structure of the main concepts for the use eleven power switch devices to divide input voltage that is replace the traditional circuit using by capacitor. Nine switches and four diodes are required to generate a nine-level output. Additional two switches and inductor will generate an output voltages balance circuit to ensure the same voltage on output capacitor. The control scheme is presented by FPGA Spartan605 evaluation kit that is produce eleven level pulse width modulation (PWM) signal pass to power switches. Nine level bi-direction multilevel major advantages for using nine-level PWM are that the voltage of each capacitor device clamping to 1/4 in the dc output voltage. Finally, a 220Vac 60Hz input voltage and 200Vdc/2kW output nine level inverter will be simulation.


Rhetorics is indissoluble to the external factors such as the author's intentions,contexts and language style and the internal factors as association,imagination and feelings.In the same way,hyperbole is closely related to the mental activities.This article elaborates the relation between exaggeration and "imagination",with practical cases as models.


from the University of Tokyo, and Caltech mathematician Matilde Marcolli, argue that quantum entanglement is the key to solve this question [5,6]. Using a quantum theory (that does not include gravity), they showed how to compute energy density, which is a source of gravitational interactions in three dimensions, using quantum entanglement data on the surface. This is analogous to diagnosing conditions inside of your body by looking at X-ray images on two-dimensional sheets. This allowed to interpret Abstract Sometimes, if you want to understand how nature truly works, you need to break things down to the simplest levels imaginable. The macroscopic world is composed of particles that are - if you divide them until they can be divided no more - fundamental. They experience forces that are determined by the exchange of additional particles (or the curvature of spacetime, for gravity), and react to the presence of objects around them. At least, that's how it seems. The closer two objects are, the greater the forces they exert on one another. If they're too far away, the forces drop off to zero, just like your intuition tells you they should. This is called the principle of locality, and it holds true in almost every instance. But in quantum mechanics, it's violated all the time. Locality may be nothing but a persistent illusion and seeing through that facade may be just what physics needs.


Pseuderanthemum malabaricum which is commonly called as the Malabar false eranthemum is widely distributed in the state of Andhra Pradesh, India. Even though the plant is widely distributed there is a lack of scientific evidence for its potential phytochemicals and their capability of medicinal usage. Hence the present study is focused on the qualitative and quantitative screening of phytochemicals present in Hexane, Chloroform, Methanol, and Aqueous extracts of P. malabaricum and to study the antioxidant activity by analyzing the capacity to scavenge 1, 1-diphenyl-2-picrylhydrazyl (DPPH) free radicals and ferric reducing antioxidant power FRAP assay. The results showed P. malabaricum is the potential source of a wide variety of phytochemicals such as Alkaloids, Phenols, flavonoids, Steroids etc. The leaves Methanol extract showed the highest DPPH free radical scavenging activity with an IC50 value of 311.51 as compared with standard Ascorbic acid which showed 109.73.


Exhaust gas temperature sensor malfunction detecting apparatus for an engine (1) having an exhaust gas purifier (3) in an exhaust gas passage (2a, 2b), comprising: an upstream temperature sensor (41) disposed in the exhaust passage to an upstream temperature of the exhaust gas at a position upstream of the exhaust purification device to detect; a downstream temperature sensor (42) disposed downstream of the upstream temperature sensor (41) in the exhaust passage to a downstream of the exhaust gas temperature at a position of the exhaust gas purification device downstream to detect; and an engine operation detecting means (5, 12, 61, 62) for detecting an operating condition of the engine, a state determining means (6, 102, 202) for determining whether the engine is in a predetermined state, estimating means (6, 106, 206) for estimating the downstream temperature of the exhaust gas based on the detected upstream temperature when the engine is in the predetermined state; and malfunction determining means (6, 107, 207) for determining a temperature sensor failure based on a relationship between the detected downstream temperature and the estimated downstream temperature with the state determining means (6, 102, 202) is used as the predetermined state a state in which the exhaust gas purifying device produces little catalytic reaction heat, the estimating means (6, 106, 206) uses a predetermined transfer function which defines a relationship between an upstream exhaust gas temperature change, and a downstream exhaust gas temperature change, characterized, in that the malfunction determination means (6, 107, 207) calculates a difference per unit time between the detected downstream temperature and the estimated downstream temperature and the malfunction is determined based on the calculated difference per unit time.


Three large earthquakes hit japan in the last few years continuously. It affected country's economy and hard to recover specially the manufacturing sector. For avoiding such impacts in the future, lessons were studied and actions were taken. This study therefore was conducted to assess the basic minimum machine tool motion behavior criteria by utilizing the existing seismic data. Particularly, the japan real earthquake data (The 2004 chūetsu and the great hanshin earthquakes as well as the 2011 Tūhoku earthquake) and mathematical models that mimic the movement of machine tools with screw jack mounting during seismic occurrence were considered and developed. For the validity, both mathematical analysis and experimental performances of a previously developed small mock-up structure of a machine tool were conducted. The study concludes that (1) the possible motion behavior of a machine tool was able to be defined and calculated; (2) using the existing real seismic data able to predict the motion behaviour of a machine tool; and (3) it was observed that up-to approximately 60 % accuracy obtained when using the real earthquake data and the developed mathematical models for analysing machine tool motion behavior.


Hensin induces terminal differentiation in rabbit kidney collecting tubule cells. Rabbit hensin and human DMBT1 result from alternative splicing of the same gene. The human DMBT1 gene is located on chromosome 10q25‐26, a region often deleted in prostate cancer. In this study we examined the potential role of this gene in terminal differentiation of prostate, as well as its role in prostatic carcinogenesis.


Modification of materials is a wide area in materials science, especially surface modification. To investigate the results of the modification process, treated and nontreated samples were compared. Intense plasma pulses of argon or nitrogen were used to irradiate the carbon steels. In all samples, the near‐surface layer was melted. Results of scanning electron microscopy investigations of the surface morphology and cross‐sections, as well as the results of tribological tests, are presented. The obtained results allowed us to draw conclusions about changes in material properties and to propose subsequent studies using other investigation techniques.


It is important to analyze students' various cognitive factors and affective factors in the learning process. The purpose of this study is to analyze...


This paper introduces the developed file-transfer system Efile, which is used in enterprises. The network communication software can be used conveniently, and it has the function of broken-point continuingly-transferring. The design scheme and key technology are proposed at length. The software is designed based on some key technologies such as multi-thread and Winsock.


Excerpt To establish criteria for objectively assessing liver status of alcoholics, 35 selected cases in various clinical stages of cirrhosis were investigated in a specially designed metabolic uni...


The present invention relates to a layered manufacturing method of three-dimensional objects. The method includes a first step of producing a layer of powder material or liquid material onto the layer which has already been compacted on the carrier or selection position, focused photon beam or focused particle beam to a selected position of the layer (8 ' ) of and a second step consisting of selective orientation. In the second step, the photon beam or particle beam is selected so as to induce absorption of the change of the material during the collision to the layer. After completion of the second step, so that the material is homogeneously compacted position of the corresponding layers in the cross section of the object to be formed, execute a third step of irradiating with electromagnetic radiation a layer (18 ') to.


Theoretical development of a nonlinear aeroelastic analysis for high-aspect-ratio wings is presented. The analysis couples a geometrically exact beam theory with a nonplanar aerodynamic theory. The aim of the present effort is to investigate the effects of geometrical nonlinearities on the aeroelastic behavior of high-aspect-ratio wings. The focus of the present work is on characterizing the physical origins of nonlinearities and assessing their relative importance. Results presented show that the structural geometrical nonlinearities have a significant effect on the structural dynamics and on the dynamic aeroelastic characteristics of a high-aspect-ratio wing. The geometrically exact calculation of the angle of attack and aerodynamically consistent application of the airloads is also important for accurate aeroelastic characterization. On the other hand, the geometrical aerodynamic nonlinearity emerging from the nonplanar wake effects is quite negligible. Nonplanar effects were negligible for both the steady and unsteady airload calculations with the assumption of a fixed wake model. r 2004 Elsevier Ltd. All rights reserved.


Starting from the exact equation for the logarithmic analysis of the C or E vs CA curve, an approximate but practically more convenient form of the same has been arrived at, which is valid for the last section of the curve. A procedure is described to arrive at the composition of a complex, formed exclusively in solution, making use of this form of the equation. It has been shown that this " rear-end logarithmic analysis" is complementary in its function to the well-known Bent and French and mole ratio methods. The utility of the procedure suggested been shown by examining its applicability to some theoretical and practical systems.


We investigate the potential of Vulkan for fluid animation using smoothed particle hydrodynamics (SPH) method. A simple parallel SPH algorithm is devised and implemented in OpenGL Shading Language(GLSL) compute shader. This GLSL code is converted into latest Standard Portable Intermediate Representation (SPIR-V) format and then implemented with Vulkan and OpenGL 4.6. Two test cases are used to verify that the implementations are correct by examining the visual output. The first test case is dropping a cube of water into a box and the second is a dam break in a closed channel, both at room temperature. And finally, we analyze the performance of both implementations in real-time graphic processor unit (GPU). We found that the most optimum of the work group size is 128, and our Vulkan implementation performs faster than OpenGL for 30,000 or greater particles.


Chevalier d'Eon de Beaumont (1728-1810) was sexually indeterminate in external appearance. By transgressing the so-called 'gender order' of the 18th century he became a victim of gender discrimination, particularly on the basis of his transvestism. The literary analysis of a pamphlet in the disguise of a fable serves as a case study of the political and religious prejudices that were incongruous with the ideals of the Enlightenment. During the subsequent centuries numerous attempts have been made to interpret the gender role, gender identity and sexual orientation of the Chevalier. The recent findings by neuroscientists with regard to sexual dimorphism shed a new light upon the case.


The most important and largest commercial outlet of fly ash in Korea is a replacement material of Portland cement in concrete industry. The high level of unburned carbon in ash brings about some malfunctions in concrete. Therefore, fly ash is refined to improve the quality as a concrete additive. In this process, a lot of the residual carbon is produced, and discarded now. In the present study, to find out a valuable outlet of the enriched carbon samples, the basic morphology of residual carbon in fly ash from Boryung power plant was investigated. The unburned carbon characterization included shape, size measurement, and chemical analysis was examined using scanning electron microscope (SEM) and energy dispersive X-ray spectrometer (EDX).


Background: Thyroid lesions are one of the commonly encountered disorders in any hospital. Majority are non neoplastic and malignancy accounts for about 5-10%. Fine needle aspiration cytology is a simple, cost effective, reliable and minimally invasive tool for the evaluation of these lesions and it can differentiate benign from malignancy.
Material and methods: This cross sectional study was conducted on the thyroid swelling attending the cytology OPD of Regional Institute of Medical Sciences (RIMS) during October, 2016 to October, 2019 a tertiary care hospital. All smears are air dried and stained with Giemsa stain.
Results: The most common age group affected is 41-50 years of age followed by 31-40 years age group. Females outnumbered males with female to male ratio of 16.9:1. Out of 729 cases, colloid goiter constitute a total of 387 (53%), Hashimto's thyroiditis 318 cases (43.3%), adenomatous goiter (1.2%) and Graves disease contribute 1.1%
Conclusion: Thyroid Swelling are very common clinical presentation. FNAC is a cost effective, reliable, easy to perform test with commendable sensitivity. It can spare patients to undergo unnecessary surgery. It also helps in differentiating solid from cystic lesions.


The development of terahertz based technology has given the opportunity for the realization of non destructive techniques capable of gaining meaningful information on delicate systems such as biological samples. Here, the health status of leaves in vivo has been monitored through a portable terahertz imaging system. The data have been extracted and analysed from the images acquired and compared with analogous results reported in the literature on similar systems. The possibilty of extracting additional information from the images regarding leaf details has also been explored.


The Athenian neoplatonist Proclus (c. 410–485) is not regarded by most analytically inclined philosophers as one of antiquity's better minds. After all, the work of Proclus with which most people are acquainted is the Elements of Theology. While one might admire its attempt at rigour in the 211 numbered propositions and their proofs, most contemporary philosophers will find the premises in these proofs pretty unlikely. Moreover, the resulting metaphysical edifice—with its various levels of entities from transcendent One to unqualified matter—is fairly alien to our more naturalist ontologies. I barrack for the St Kilda Football Club, so it should come as no surprise that I like to see the rehabilitation of the downtrodden and underappreciated. In what follows, I'll argue that some of Proclus' arguments are at least as worthy of our attention as one of Aristotle's most celebrated arguments in natural philosophy. Part of what we admire about Aristotle is the methodology and cleverness. He proceeds in a way we approve of, first identifying the problems that arise when we survey the 'platitudes' about a topic and then clearing away many of these by drawing distinctions among the various senses of words. He typically offers a theory and tries to justify it by showing that it is better than its competitors at saving the appearances. Even when Aristotle gets to the wrong conclusion, we still find that he does things that we regard as methodologically virtuous in the process.


Despite the adoption of a national immunization program in China, the incidence of mumps remains high. This study aimed to describe the epidemiological characteristics, including the time, region, occupation, and age, of mumps in Wuhan from 2005 to 2018 and to evaluate its transmissibility. In this study, the susceptible–exposed–infectious–asymptomatic–recovered (SEIAR) model fitted the actual incidence data of mumps. The effective reproduction number (Rt) was used to evaluate and compare the transmission capacity in different areas. From 2005 to 2018, there were 36,415 cases. The incidence of mumps was highest among people aged 5–10 years (460.02 per 100,000). The SEIAR model fitted the reported mumps data well (P < 0.01). The median transmissibility (Rt) was 1.04 (range = 0–2.50). There were two peak spreads every year (from March to May and from October to December). The Rt peak always appeared in the first 2 months of the peak incidence rate. The peak time of the epidemic spread of mumps was 1–2 months earlier than the peak incidence rate. The prevention and control measures of vaccination for children aged 5–10 years should be taken before the peak transmission capacity each year, 2 months before the peak of the outbreak, to reduce the spread of mumps.


Supplemental Digital Content is Available in the Text. Through this meta-analysis, we demonstrate no significant difference in the incidence of early or late age-related macular degeneration between statin users and nonusers. Furthermore, in patients with existing AMD, statin use had no significant influence on the subsequent development of choroidal neovascularization or geographic atrophy. Purpose: Age-related macular degeneration (AMD) shares many of the same risk factors with atherosclerosis. There is a postulated role of lipid-lowering agents in preventing AMD. This meta-analysis investigates the possible role of statins in the prevention of AMD onset and progression. Methods: MEDLINE, EMBASE, Cochrane CENTRAL, and the reference lists of included studies were systematically searched from inception to September 2020. Studies were included if they measured the risk of AMD development or progression with statin use. The primary outcomes assessed were AMD incidence and progression. Secondary outcomes were the incidence of early AMD, late AMD, choroidal neovascularization, and geographic atrophy. Results: Twenty-one articles (1 randomized control trial and 20 observational studies) collectively reporting on 1,460,989 participants were included. The pooled risk ratios (95% confidence interval) for statin use on any, early, and late AMD incidence were 1.05 (0.85–1.29) (P = 0.44), 0.99 (0.88–1.11) (P = 0.86), and 1.15 (0.90–1.47) (P = 0.27), respectively. In patients with existing AMD, the respective risk ratios for statin use on incidence of AMD progression, choroidal neovascularization, and geographic atrophy were 1.04 (0.70–1.53) (P = 0.85), 0.99 (0.66–1.48) (P = 0.95), and 0.84 (0.58–1.22) (P = 0.36). Conclusion: This meta-analysis found that there was no significant difference in the incidence or progression of AMD based on statin use.


Hypoid gear dynamic emulate analysis is operated with ANSYS/LS-DYNA software for that the fatigue failure probability of hypoid gear is the most high in tooth surfaces contact fatigue resistance. The contact stress and deformation during the meshing process are got. And the distribution of contact force is calculated when two pairs of teeth contacting simultaneously.


When Robert Sdiumann äs music critic saw basilisk eyes in Chopin's notes äs they appeared on the printed page, he was perhaps foreshadowing a trend in the way in whidi writers of the late XIX Century were influenced by Chopin's music. At first, the impact of Wagner's music tended to overshadow that of his less flamboyant predecessor; nevertheless, the music of Chopin was producing its own impact, psychologically, on a group of writers whose early Output reflected the mood of the fin-de-siecle in Europe. Their selection of the Chopin repertoire tuned to one predominant mood, namely its langour, melancholy and ceaseless yearning, mirrored the growing disintegration of a culture whose over-refinement was lapsing into decadence. Thus basilisk, with its overtones both magical and ominous, suggests the symbol for the growing wave of aestheticism with which the cult of Chopin came to be associated. In literature the expression of the Chopin cult found its way into the early writings of Thomas Mann, Hermann Hesse, and eventually John Galsworthy. Later, äs the twentieth Century progressed and the pendulum swung in a new direction for the arts and for literature, a suitable antidote to the basilisk was to be found in the parody of the Chopin cult offered by T. S. Eliot in his poem Portrait of a Lady and in Chopin by Gottfried Benn, which explores the use of biography in a poem, and moves away from the extreme subjectivity of many XIX-century portrayals of the Polish composer. It is the purpose of this study, however, to look at the image of Chopin in a selection of literary works which mirror the late XIX Century, and to show that the choice of Chopin's music at that time reflected a spiritual malaise less characteristic of the composer, perhaps, than of those who made use of his music in their writings. After Chopin's death in 1849, the second half of the XIX Century was to see changes political, religious and social which would reduce the world of the composer to a nostalgic memory. Socially, the main changes were the result of the ever-increasing industrialization which was to provide wealth and a new class of financiers to spend it. The aristocrats by birth for whom Chopin had performed, that select group upon whom he had lavished so much of his creative energy were now being replaced by a new ruling class: the men of


mtDNA haplotypes of 91 strains on Phytophthora infestans(Mont.)de Bary were identified based on the technologies of PCR and RFLP using two pairs of primers F2/R2 and F4/R4 to amplify the polymorphism regions of P2 and P4.The results showed that there were two typies of mtDNA haplotype:Ib and IIb,and the type of IIb was the priority one which covered 94.5% of the strains tested.


Aiming at the problem that the co-combustion of a large amount of lignite in thermal power plants will cause inadequate drying capacity of coal mill and subsequently affect the safe operation of coal pulverizing system,a retrofit was implemented by changing the rotating direction of air preheater,increasing the angle of primary air chamber,mounting flexible seal to the air heater,and making capacity expansion to the mill nozzle,etc.Results show that after retrofit,the temperature of inlet hot primary air is further increased,the drying and milling capacity of coal mill are significantly raised,and the fan resistance is reduced;on the basis of meeting the requirement of co-firing a large-proportion of lignite,the fan power consumption is reduced,the stalling risk of primary air fan is lowered,which will bring enormous economic benefits to the enterprise.


Arab nationalism may be divorced from association with religion, whether Islam or Christianity. Professor Watt, on the other hand, looks for a rapprochement, even a merger, between the three religions treated in this work. His view may appear to be visionary within the present tensions. But it is surely in keeping with progressive religious thought and the traditional all-embracing role of religion in the Middle East. So swiftly do events move in the Middle East that much in these two volumes (written, it appears, in 1965) is now out of date. Some of these events could not have been forecast— the cataclysmic outcome of the war of June 1967 and the death of Nasser; others, like the torment of Nigeria and the political bouleversementa of the Sudan, Libya, and the Yemen might have been predicted, if hesitantly. It is to be hoped that this work will succeed so well —as it deserves to succeed—that soon the authors will have the opportunity to revise their articles in the preparation of a second edition.


The rotational streaming of cytoplasm in barley root hairs has been stimulated about 1.3–1.8 times through continuous treatment with various solutions of myo-inositol. The stimulation attained the same level as after ATP administration and was dependent on the external myo-inositol supply with the employed concentrations. The stimulation was cut off by simultaneous treatment with myo-inositol and uranyl salts. By using uranyl acetate the rate of streaming was maintained about the value of the control. The uranyl chloride caused an inhibition in the rotational streaming and later made it to cease altogether. The simultaneous treatment with myo-inositol and 2.4-DNP (dinitrophenol) induced a quick inhibition in 60% of the root hairs. consecutively stopping rotational streaming.

It is assumed that the stimulation of rotational streaming is not due to the direct effect of myo-inositol but to ATP formed in the reaction: inositol hexaphosphate ++ ADP ATP + inositol. According to the results obtained by testing with uranyl salts, the phosphorylation of inositol probably takes place at the cell surface. The effect of 2,4-nNP points to the presence of two competitive metabolic processes involved in ATP consumption: the upkeep of rotational streaming and the uptake of substances by the plant cell.


Abstract The Holiness Code in Leviticus, in which the proscription against homosexual behavior is included, was intended to keep the Hebrews separate from the Canaanites. Neither Jews nor Christians practice it today. More importantly, the ministry of Jesus was based on inclusion, rather than exclusion. Pastoral experience demonstrates the needs of people to be supported and welcomed. There is room for homosexuals in the church. They can be nurtured to become part of faithful, stable, loving relationships.


A rolling bearing with an integral retainer made from carbon graphite or electrographite comprises a bearing outer ring, an inner ring, a rolling body embedded between an outer ring raceway and an inner ring raceway and a retainer for uniformly separating the rolling body along the circumferential direction, wherein the retainer is integrated by carbon graphite or electrographite tube materials or ring materials through machining. The utility model adopts the integral retainer made from the carbon graphite or the electrographite with high-temperature resistance, low-temperature resistance, corrosion resistance, high strength and excellent self-lubricating property and machining property, so that the retainer is no longer a short slab for restricting the operating temperature upper limit, the operating temperature lower limit and corrosion resistance of the bearing. The integral retainer made from the carbon graphite or the electrographite is used under the environment of ultrahigh temperature, ultralow temperature or strong acid, alkali and salt medium intrusion, in which lubricating oil or lubricating grease is incompetent, so that the bearing does not need to be filled with the lubricating oil or the lubricating grease, and the utility model has great engineering application value.


Abstract This descriptive study of language use examined the extent to which bilingual Hispanic young adults used their two languages in varying aspects of their lives and analyzed the extent to which they maintained the use of Spanish in these domains. A convenience sample of 202 undergraduate, Hispanic university students completed the Language and Education Survey (Hasson, 2001). Data from the Language Use section of this instrument was the basis for the present study, which compared Hispanic students who were enrolled in bilingual or English for Speakers of Other Languages (ESOL) programs in their elementary schooling with students who experienced an all-English curriculum. The results of this study showed that while there was a definite shift toward English in this sample, there were nevertheless significant differences between the Bilingual/ESOL group and the All-English group in the very specific dimension of language use. The findings raised some critical questions regarding how school systems address the particular needs of bilingual students and how this might affect the maintenance of their native language and its use in later life.


Well-known variational principles for second-order perturbation matrix elements are extended to higher-order multiphoton processes for atomic hydrogen. Numerical applications to two- and three-photon ionization of the hydrogen ground state provide results comparable to those of analytic calculations, even near intermediate-state resonances, yet without the complications involved in summation over intermediate states. Extensions to multiphoton processes for many-electron atoms are discussed briefly.


New techniques for Walsh-Hadamard spectral analysis are reported, for which spectral coefficients are updated in real time with each new signal sample.


Oscillations in high-frequency tubes are regular and important problems for their use and development. The limitations of the Bers-Briggs criteria, generally applied to uniform systems, are avoided here by a method based directly on the differential equations that describe the electronic device. One must then find the parameters and the boundary conditions that are appropriate to determine the different types of operation or instabilities. This method is general enough to be used on a wide range of tubes (Traveling Wave Tubes, Gyrotrons, Free Electron Laser, ...). An original criterion for characterization of the build-up of oscillation is applied to traveling wave tubes with a good match to the results obtained by experiments.


This article discusses physical activity and sport as a good way to overcome deviant behavior in children. A number of characteristics of sporting activity are identified , which define it as useful not only for the physical but also for the psychological, emotional and overa ll development of the personality. Organized extracurricular sports activities are mentioned as a good means of organizing the leisure time of the students. Of course, sport is not a universal remed y for the problems of society and the deviant behavio r of children. But it is one of the working options f or prevention and overcoming deviant behavior, especially if it is a result mainly of the child's personal characteristics such as aggression, temperamental behavior or adrenal dependence. Affiliation to the team gives the child certainty t hat they area member of a community where they give and receive permanent support. The pursuit of personal achievement reflects the development of the child and directs his or her energy in a positi ve direction. Achieved success boosts self-confidence and self-esteem that are so necessary to young people especially in teen years. Driving into discipline in sport will lead to compliance with social norms and public laws. Key word: sport activity, deviant behavior, self-confidence, personal success, motivation, leisure time, motor activity, health lifestyle. Health culture and physical activity are of essential meaning for preventing health at any person's age. A healthy lifestyle is a specific type of system of vital activities aimed to preserve and improve health of the individual and society as a whole. This is achieved through the personal health culture, the value orientation and the motivation of the person (http://zdrave.org). Every kind of motor activity in reasonable dosage: improves the vital activity of all organs and systems in the body; increases mental and physical performance; strengthens the protective forces. Motor activity is one of the main factors for primary health prevention. On the one hand, it counteracts the hyper dynamics, which is a risk factor for the occurrence of many socially significant diseases. On the other hand, as a result of systemic physical stress, structural and functional changes in the body are achieved, stress is reduced, leisure time is used well and tunes positive (http://www.4fitnessbg.com/articles/view/ 3.htm; http://medicina-bg.info). Motor activity causes: → Excitement associated with motivation to perform an exercise or the outcome of the game. But when the excitement is beyond the accepted it is supposed to be one of the reasons for the occurrence of deviant behavior. (JPMNT) Journal of Process Management – New Technol ogies, International Vol. 5, No 3, 2017.


On 8 July 2008, the Court of First Instance (CFI) handed down its judgment in an appeal by AC Treuhand AG against the European Commission's decision of 10 December 2003 finding a breach of Article…


The presence of a bulky peripheral wedge destabilizes the homo-assembly of an amide functionalized acceptor monomer and thereby enables alternating supramolecular copolymerization with an amide appended donor monomer via the synergistic effect of H-bonding and the charge-transfer interaction.


The paper deals with a technique to improve the signal extraction from the target of scan conversion-based transient digitizers. At first, the statistical parameters of the digitized charge distribution on each target column are analyzed. Then the statistical parameter trend across the target is evaluated. Finally, the identification of the distribution charge model allows the signal extraction to be improved. Experimental results of tests carried out on an actual scan converter using dc and sinewave signals showed that signal extraction can be improved mostly by correcting the center displacement of the column distributions.


Background:  The PREDICTIVE™ study is a multinational observational study designed to follow up patients with diabetes who started insulin detemir (IDet) in routine care. Recruitment started in June 2004 and is ongoing in some countries.


A new mechanical device consisting of a set of safety membranes has been used in several small hydropower stations in China in lieu of a surge tank. Safety membranes are controlled weak points mounted on the penstock near the powerhouse. Whenever pressure on the membranes rises to the preset value, one or more membranes rupture, protecting the penstock and the unit effectively. The device is simple, reliable, and beneficial. This paper proposes a mathematical model for analyzing hydraulic transients of a hydropower plant where a set of safety membranes is mounted to replace an expensive surge tank. The prevailing method is employed in order to solve the momentum and continuity equations describing transient flow in closed conduits. An optimization procedure is developed to guarantee the convergence of the interative process for calculating pressure rises due to water hammer when Kaplan turbines are installed. Using this model, transients of generator load rejections are calculated in Linzhengqu hydropower...


The new compound SrSb4S7 · 6 H2O crystallizes in the monoclinic system, space group P21/n with lattice constants a = 2765,4(8) pm, b = 731,5(3) pm, c - 897,2(3) pm, ß - 90,4(1)°. In the structure there are anionic (Sb4S72-)∞-strings, which are arranged parallel in sheets and separated by the hydrated Sr2+ ions


Cognitive neuropsychology explained the mechanism of acquired dyslexia as selective impairment for task specific procedures, such as grapheme-phoneme translation route for non-word reading. Recently, in the framework of connectionist triangle model of reading, "Primary System" hypothesis explained the acquired dyslexia as the impairment in different primary system (e.g., visual, phonology and semantics). Both the reading and non-reading task was influenced by the deficit in these primary systems. This approach suggested a new mechanism of all kinds of acquired dyslexia, as well as the relationship between dyslexia and other cognitive functional deficits. This paper elaborated it in the detail.


A computational model for quenching simulations of thin plates has been developed. The model is examined by comparisons with experiments with one-sided water spray cooling. With this experiment, th ...


The invention discloses a refrigerator and a liner thereof. The liner of the refrigerator comprises a cold storage liner, a first groove cover plate and a refrigerating liner, wherein the rear wall of the cold storage liner is provided with a first groove sunk forwards; at least one of the upper end and the lower end of the first groove is opened; the wall of the first groove is provided with a first air hole; the first groove cover plate is arranged on the rear surface of the cold storage liner and covers the first groove to ensure that a cold storage air channel is defined by the first groove cover plate and the first groove; and a refrigerating air channel which is communicated with the cold storage air channel is formed in the refrigerating liner. The liner of the refrigerator of the embodiment of the invention is provided with the cold storage air channel, so that air channels are not required to be formed on the inner wall of the liner.


Through the field investigation in Xionger Mountain,it was found that the scenic area is rich in tourism resources.However,the development of tourism is lagging behind.By the method of random sampling,a survey for visitors was conducted.A total of 100 questionnaires were issued,100 of which were valid.With the help of TSI evaluating model,tourists' satisfaction degree was calculated accurately.The results showed that ratio of tourism performance to price in Xionger Mountain wasn't high,of which tourists generally expressed dissatisfaction;that the overall environment was quite good,of which tourists showed higher satisfaction degree;that some tourists' expectations to this scenic area were not high;that revisit willing was comparatively high;that there was a certain gap compared with other scenic spot.Tourists' satisfaction degree on Xionger Mountain is 55.89% through calculating TSI index.Finally,aiming at the existent problems,some countermeasures for improving the tourists' satisfaction degree on Xionger Mountain were put forward from the aspects of tour value,environmental perception,marketing philosophy and modes.


lim n→∞ ||u− û||2 (2) In words, when we consider convergence we are asking the question of how the numerical solution approaches (or does not approach) the exact solution as the number of discretization points grows infinitely large (we could equivalently consider the limit as ∆x → 0). The aim of this section will be to characterize the convergence behavior of our 2nd-order finite difference method. To facilitate this, let us define the error vector e := u− û, and write the matrix system from the last lecture more succinctly as Aû = f . Now note that


This paper puts forward a fast algorithm for heating injection mold by water accordance with these problems that the computing is enormous to simulate heating injection mold and there is a limitation for velocity of hot water that it should not be too larger otherwise simulating algorithm will be failure. The method does the similarity transformation to construct similarity model whose solution is the same with the mathematics model for the problem of heating injection mold by water, and the simulation time will be reduced greatly at the precondition of keeping precision using the similarity model. The first step of similarity transformation is time similarity transforming for the fluid governing equation describing the moving of hot water in the time area, i.e., actual heating time area for mold heating is transformed to heating time area of similarity model while keeping spatial domain unchanged. Meanwhile it does the same transformation for the heat conduction governing equation in the time area, also keeping spatial domain unchanged. In this way the similarity model of the origin mathematics model for fluid-solid coupling problem of heating mold by water is obtained. Simulating the similarity model could obtain mold temperature field after heating fast. The paper shows that the fast algorithm has good application value through examples.


Stimulated emission and optical gain problems are reviewed on the basis of analysis of highly photoexcited III-Nitride and ZnO wide-gap materials. Spontaneous and stimulated emission along with optical gain of these materials in UV region is analyzed. The possible mechanisms of inverted population in In-containing materials and ZnO semiconductors are discussed involving mechanisms of dense electron-hole plasma, carrier (exciton) localization, as well as various interaction processes in dense exciton gas.


John Burnside, On Henry Miller: Or, How to Be an Anarchist Princeton University Press, 2018. Pp. 175. ISBN 978-0-6911-6687-2. Wayne E. Arnold Reading through Henry Miller's early draft of Tropic of Capricorn (1939), held at the Beinecke Rare Book and Manuscript Library, Yale University, the reader quickly realizes that Miller made a pretty wise decision to scrap his first draft of the book and continue anew in a completely different vein. Such decisions to disregard rough drafts must be painf...


The article is revealed actual problems of qualimetry of innovations in the educational environment. In information theory to determine the degree of incompleteness, uncertainty of knowledge in the information system calculated its entropy. As a measure of the indicator of the educational system is proposed to use the level of entropy in marks. This will make the process easier and analysis, and its results more accessible for practical use in a particular educational environment. The criteria for assessing the level of entropy in the system of higher education can serve as a drop in the level of formation of subject concepts. In this critical level of entropy will correspond to the almost complete absence of formation of subject concepts. So it's proposed to estimate the expected effect of a didactic introduction of various innovative technologies in the educational system of higher education based on the entropy approach.


Tungsten disulfide (WS2) monolayer is a direct band gap semiconductor. The growth of WS2 monolayer hinders the progress of its investigation. In this paper, we prepared the WS2 monolayer through chemical vapor transport deposition. This method makes it easier for the growth of WS2 monolayer through the heterogeneous nucleation-and-growth process. The crystal defects introduced by the heterogeneous nucleation could promote the photoluminescence (PL) emission. We observed the strong photoluminescence emission in the WS2 monolayer, as well as thermal quenching, and the PL energy redshift as the temperature increases. We attribute the thermal quenching to the energy or charge transfer of the excitons. The redshift is related to the dipole moment of WS2.