The familiar story that organizes "normal" female adolescent sexuality is a romance narrative in which a (good) girl, who is on a quest for love, does not feel sexual desire—strong, embodied, passionate feelings of sexual wanting. In this story, sexual desire is male; it is intractable, uncontrollable, and victimizing. There continues to be no readily available image or story of a normal girl who has and responds to her own sexual desire. Following a social constructivist perspective, the ways in which we do and do not "story" sexuality into being are definitive in how we make meaning out of our bodies and our relationships, and so the ways in which we do and do not speak about sexuality are crucial. This perspective also suggests that providing critiques and alternatives to sanctioned stories can be a crucial intervention. This point is illustrated by following the stories that are available to one girl for understanding her sexuality, and by portraying the tensions, revelations, and challenges that the interplay between these stories and her lived experiences produce. The use of a method for analyzing narratives to develop an understanding of adolescent girls' sexuality in terms of their own desire is described. The article presents an analysis of a case from the author's current exploration of how girls' knowledge and experiences of their bodies and of their desire is shaped, enabled, and undermined by stories available in the culture about female intimate relationships and sexuality.


Experiments were conducted using dry tobacco (Nicotiana tobaccum) leaves aqueous extract to determine the acute toxicity and sub lethal effects on some haematological indices of Oreochromis niloticus using static renewable bioassay method. The extract was found to be toxic with a 48-h LC50 value of 109.6 mg/l. Sub lethal concentrations of the extract were found to have an inverse relationship with the haematological indices assessed. Statistical analysis using ANOVA revealed that there was a significant difference (P Key words : Toxicity, tobacco, haematology, Oreochromis niloticus
Journal of Aquatic Sciences Vol.17(1) 2002: 5-8


It presents the exterior circulation cooling system of guide vane for turbogenerator units No.1~4 of Wanjiazhai Multipurpose Dam Project,and the existing problems concerning erection position and electrical control.By renovation,the above problems were basically solved,which provides safety operating condition for turbogenerator units of Wanjiazhai Multipurpose Dam Project.


Background: Diffusion tensor imaging (DTI) has been used to characterize forearm muscle architecture. Since only uniform sampling is performed for seed points rather than fiber tracts, the tracts may be unevenly distributed in the muscle volume. Purpose: To reconstruct uniformly distributed fiber tracts in human forearm by filtering the tracts from DTI. Assessment: Farthest streamline sampling (FSS) was proposed for filtering and compared with two conventional methods, i.e., two-dimensional sampling and three-dimensional sampling. The uniform coverage performance of the methods was evaluated by streamline coverage (SC) and the coefficient of variation of streamline density (SDCV). Architectural parameters were calculated for 17 forearm muscles. Anatomical correctness was verified by 1. visually assessing the fiber orientation, 2. checking whether the architectural parameters were within physiological ranges, and 3. classifying the architectural types. Results: FSS had the highest SC (0.93+0.04) and the lowest SDCV (0.34+0.06) among the three methods (P<0.05). FSS reduced the sampling of long tracts (10% reduction in fiber length, P<0.05), and the architectural parameters were within physiological ranges (two parameters with P<0.05). The fiber orientation of the tractography was visually consistent with that of the cadaveric specimen. The architectural types of 16 muscles were correctly classified, except for the palmaris longus, which had a linear arrangement of fiber endpoints (R2=0.95+0.02, P<0.001). Data Conclusion: FSS reconstructed more muscle regions and uniformly distributed fiber tracts. The tracts were anatomically correct, indicating the validity of fiber tracts. Key Words: diffusion tensor imaging; forearm muscles; architectural properties


CoFe2O4 hollow nanoparticles with an average diameter and shell thickness of about 9.0 nm and 3.0 nm, respectively, were grown on graphene sheets. The hybrid exhibited excellent electromagnetic wave absorption properties with all of the minimal reflection losses below −10 dB at a thickness of 1.5–5.0 mm, superior to the hybrid based on CoFe2O4 solid nanoparticles and recently reported absorbers. Our results open a novel way for fabrication of hollow nanoparticles on graphene sheets for high-performance electromagnetic wave absorbers.


The chemistry of vanadyl porphyrins has been explored using vanadyl octaethylporphyrin as a substance in petroleum porphyrins, crude oils and bitumen. The structural, electronic, thermodynamic, spectroscopic properties are described. The geometry's optimization of this molecule was done by Density Functional Theory (DFT) using the hybrid Beck three-parameter hybrid functional combined with Lee-Yang-Parr correlation functional (B3LYP) and 6-31G(d) standard basis set. All calculations have been made in the gas phase and in different solvents: benzene, benzonitrile, tetrachloromethane and chloroform. The calculated infrared spectrum was compared with experimental spectroscopic data, and the vibrational assignment was provided. An electron density analysis in terms of natural bond orbitals was conducted to determine the nature of the bonds between the vanadium and nitrogen atoms. The spatial representation of the associated molecular orbitals helped to explain the formation of the V-N bonds and to interpret the chemical reactivity of the compound studied. The electrostatic potential was calculated in order to investigate the reaction properties of the molecule.


In this paper we discuss the human resource development of Birbhum District. The data have been collected from District Statistical Handbook, District census report of 2001 and District Human Development Report 2009.A large part of the Birbhum District is still backward with respect to human resource development. Aim of this paper is to study the cause of the backwardness of this district. "HRD is the process of determining the optimum methods of developing and improving the human resources of an organization and the systematic improvement of the performance of employees through training, education and development and leadership for the mutual attainment of organizational and personal goals" (Smith). HRD is an important topic of present time. It is considered by management professionals, as sub discipline of Human Resource Management( HRM), but many researchers have, broadened the scope and integrated the concept of HRD by looking it from socioeconomic angle and giving it other dimension such as physical, intellectual, psychological, social, political, moral and spiritual development.


BURGEFF' has brought together the extended results of his own research and those of other students upon the root-fungi of orchids. The volume contains a comprehensive citation of literature, several tables summarizing results of experiments, and discussions of the theory of the mycorhiza question. By way of introduction, BURGEFF defines his use of the word symbiosis as that relation of two symbionts in which one aids the other in any way, if only to make existence possible under conditions otherwise impossible. After union, the two organisms form a new organism, a unit, which takes up the struggle for existence under new conditions, each being a body member. Such is claimed to be the condition of the orchids and their root-fungi. The two sections of the work are as follows: i. The study of the fungus independent of the plant.-On a culture medium of agar and rain water with a slight trace of starch, 29 root-fungi, aseptically obtained from native and tropical orchids, were grown (holosaprophytic ones were unsuccessful). Such species of Orcheomyces, as the author chooses to call the fungi for convenience, are described in detail as to their structure and behavior in the culture. For the first time a study of their enzymes has been made, and the endophytes were grouped accordingly on the basis of their biological relations to the orchids. In general they have thin-walled, regularly septate mycelia; the hyphae are sharply differentiated into Langhyphen that branch little and show unlimited growth in one direction, and Kurzhyphen that are of smaller caliber and arise at regular intervals and whose cells under certain conditions are transformed into spores (Sporentrdger) or absorptive hyphae (Sanghyphen). In old age spores and hyphae contain a fatty oil. Chains of hyaline or slightly colored spores may unite into loose clusters or closer sclerotia-like groups. All fungi fuse or anastomose in some manner. The hyphal cells contain two to ten nuclei, but the spores contain only two nuclei. Spiral knots initiated in cultures by the surface tension of a drop of water at the tip of the hypha are comparable to those in the root cells developed in response to the pressure of the resisting plasma membrane to the penetration of the hypha. No sexual reproduction was observed.


Abstract : Two approaches are analyzed for achieving the efficient assignment of reliability norms to the various units of a digital computer, e.g., the arithmetic unit (AU), the control unit (CU), and the main memory unit (MU). The problem consists in finding the failure rate of these units which will satisfy a given probability of machine failure Q(T) in time T. In the first approach the approximate failure rates are expressed as functions of the complexity of units and the relative failure rates of the components. A more realistic view of the failure rates of the units must take into account their manufacturing and operating costs. The authors derive an expression for finding the failure rate of individual units for which the cost of a unit is minimum taking into account the cost of the entire computer complex.


A common process control application is the cascaded two-tank system, where the level is controlled in the second tank. A nonlinear system identification approach is presented in this work to predict the model structure parameters that minimize the difference between the estimated and measured data, using benchmark datasets. The general suggested structure consists of a static nonlinearity in cascade with a linear dynamic filter in addition to colored noise element. A one-step ahead prediction error-based technique is proposed to estimate the model. The model is identified using a separable least squares optimization, where only the parameters that appear nonlinearly in the output of the predictor are solved using a modified Levenberg–Marquardt iterative optimization approach, while the rest are fitted using simple least squares after each iteration. Finally, MATLAB simulation examples using benchmark data are included.


In this paper we analyze some iron spurs gold recovered in the burial of a knight of the thirteenth century in the monastery of Corias (Asturias, Spain) First, it exposes a stratigraphic context assessment and a description of the spurs; in a second part establishes the chronology of the spurs from comparative analysis with other examples recovered in the different kingdoms of the Iberian Peninsula; and finally performs a socioeconomic and political contextualization of the order of knights in Asturias in the thirteenth century.


[Publications of the Society of Bibliophiles in Krakow (1922-1962)] The Society of Bibliophiles, established in 1922 in Krakow, the leading bibliophile society of the inter-war period, greatly contributed to the cultural output of the country. The Society realized its goals through organization of lectures, exhibitions, bibliophile auctions. However, a particular emphasis needs to be placed on the publishing activity of the society comprising book publications, magazines and leaflets. The article presents general characteristics of the publications of the Society and a few selected representative positions, which were described in detail. The society created a peculiar type of book - a bibliophile publication, realizing the format of ascetic typographical beauty. The characteristic features of the publications of the Society of Bibliophiles were the lightness and transparency of composition resulting from the operation with the printing material


The author discusses the following issues concerning hepatitis C: stigma, prevention, education, needle sharing, compensation, and support programs. (non-author abstract)


The influence of different doses of nitrogen, phosphorus and potassium on gladiolus cv. Jester Gold was studied in a field trial conducted by factorial randomized block design. The effect of nitrogen (20, 40, 60, 80 g/m2) with phosphorus (5, 10, 20 g/m2) and potassium (15, 20, 25 g/m2) and control applied to the plants on post-harvest life of cut gladiolus spikes were studied under laboratory conditions. Longevity of first floret was increased by application of N80P5 g/m2. A dose N60K20 and N80P10 g/m2 was producing bigger first and third fully opened floret, respectively. Application of N80K20 g/m2 resulted into maximum fully opened florets and total florets/spike in the vase. Effective useful life, vase-life, water uptake on third day and at senescence in the vase was increased by the use of N60P20g/m2. A fertilizer dose of N80P20 g/m2 resulted into maximum increment of spike length at senescence, fresh weight of spike at harvest, at third and fifth day in the vase.


This paper introduces the writing section of the National English Ability Test (NEAT) developed fbr eollege entrance exam in Korea, It will discuss the nature of the writing tasks of the NEAT, rating domains and rater training procedure.


A numerical technique is developed to analyze the electronic state in coupled semi‐infinite semiconductor superlattices. It is found that the superlattice miniband shrinks to discrete energy levels near the surface, and localized electronic surface states with energy falling within the ministop gap exist under certain conditions. Numerical calculations are also compared with results from an exact eigenvalue equation.


:- With the growth in technology, education system have also seen a lot of improvement. But still monitoring of student attendance using traditional system consumes too much time which could be employed in a better way inside the classroom. Small changes can tremendously affect bigger changes. Moreover, automated attendance system can help us to check whether a student is sleeping inside the classroom or whether he is proactive inside the classroom. Classroom Management Behavior System can gives us a concise idea of the various emotions students are face inside the classroom. This paper describes different methods used for attendance marking and detection of the level of attention paid in class by students.


Self-enhancement models posit a general motive to enhance self-regard that is believed to be particularly strong in people with low self-esteem. We extended previous laboratory research with college students to a field setting and studied the attraction responses of child athletes to coaches who differed in their observed behavior patterns during the sport season.


This paper describes the design of a robust control system for a gun turret testbed called the ATB1000. The control system incorporates a control scheme based on sinusoidal-input describing function (SIDF) models of the testbed's drive subsystem to reduce the effects of backlash and nonlinear friction, and a dissipative control scheme to make the control system insensitive to the unmodeled dynamics and parameter imprecision associated with the flexible modes of the wheel/barrel subsystem.


Ferroelectric, piezoelectric thin film material and processes are gaining more and more importance for innovative devices that are focusing on miniaturization, high performance and integration. A piezoelectric thin film MEMs platform has been developed that enables miniaturized ultrasound transducers that operate in the frequency range of >50 kHz up to >10 MHz. The thin film ultrasound transducers show a high quality and reliability. With this technology platform ultrasound transducers have been developed that operate at 60–90 kHz and show a coverage >25 m2 at a low operating voltage of 12 V. The same technology platform has been used to realize ultrasound transducer arrays operating at 3–10 MHz. Ultrasound images have been demonstrated with these piezoelectric thin film transducer arrays.


The propagation speed of an acoustic signal is much slower than the speed of a terrestrial radio signal due to the physical characteristics of an underwater acoustic channel. This large delay can impact the throughput of the channel. There is a very high delay variance which presents unique challenges to the designs of efficient protocols. The inconsistent delay renders many traditional communication protocols insufficient since they rely on accurate estimations of the round trip time (RTT) between two communication nodes. Underwater acoustic channels are inherently unreliable with connection interruptions. In this paper we present a unique approach to develop a prediction based delay-tolerant protocol (PBDTP) to address these problems. The PBDTP protocol can tolerate long delays, inconsistent delays and connection disruptions by predicating a value for a sensor node if its data were not received at the sink node instead of having the sensor node retransmit its data. The PBDTP can reduces data traffic over the networks and uses the network resource more efficiently.


The properties and predictions of several new Regge models, suggested by the Serpukhov total-cross-section data, are analyzed and compared. Forward elastic $\ensuremath{\pi}N$, $\mathrm{KN}$, $\overline{K}N$, $\mathrm{NN}$, and $\overline{N}N$ scattering are considered, for Regge models incorporating strong multi-Pomeranchukon cuts, or Regge dipoles, or complex secondary trajectories. Total cross sections are fitted. Forward real parts, charge-exchange scattering, and regeneration are predicted, within subtraction constants. High-energy extrapolations are shown.


Developing reliable computational frameworks for early parasite detection, particularly at the ova (or egg) stage is crucial for advancing healthcare and effectively managing potential public health crises. While deep learning has significantly assisted human workers in various tasks, its application and diagnostics has been constrained by the need for extensive datasets. The ability to learn from an extremely scarce training dataset, i.e., when fewer than 5 examples per class are present, is essential for scaling deep learning models in biomedical applications where large-scale data collection and annotation can be expensive or not possible (in case of novel or unknown infectious agents). In this study, we introduce ProtoKD, one of the first approaches to tackle the problem of multi-class parasitic ova recognition using extremely scarce data. Combining the principles of prototypical networks and self-distillation, we can learn robust representations from only one sample per class. Furthermore, we establish a new benchmark to drive research in this critical direction and validate that the proposed ProtoKD framework achieves state-of-the-art performance. Additionally, we evaluate the framework's generalizability to other downstream tasks by assessing its performance on a large-scale taxonomic profiling task based on metagenomes sequenced from real-world clinical data.


Effects of hormones including NAA, IAA, 6-BA on leaf differentiation of Populus euphratica and antibiotics including Kanamycin (Kan), G418, Carbenicillin (Cab), Cefotaxime (Cef) on the growth and differentiation or rooting of various explants of P. euphratica were studied. Genetic transformation system mediated by Agrobacterium and optimum antibiotic concentrations for modified organism selection of P. euphratica were founded. Results shown that: the optimal culture medium for leaf differentiation of P. euphratica was MS+BA 0.5mg/L+NAA 0.1~0.2mg/L+sugar 25g/L+agar 5g/L; at co-culture stage which leaves were used as explants, the optimum concentrations of Kan, G418, Cab and Cef were 10mg/L, 7.5mg/L, 200~600mg/L, 200~400mg/L respectively; at the stage of subculture or rooting of resistance buds, the optimum concentrations were 15~20mg/L, 10~15mg/L, 200~800mg/L, 200~600mg/L respectively.


The small-country price-taking assumption of Oates and Schwab is relaxed to consider a large open economy that can influence its net capital return. This creates an incentive for the country to distort its policies. The key question asked is whether this induces inefficient outcomes. The result is that if the country has a dedicated tax on capital and uses this tax optimally, the Oates and Schwab first-best result still holds. However, efficiency in a large open economy requires that the tax on capital be nonzero, unlike Oates and Schwab where the capital tax must be zero for first-best efficiency.


The latest Support to Participation in EU Programs project sparkles growing interest in investigating management mechanism of creating efficient project leadership in higher education. The Project reveals significantly different variables in hard core sciences research topics prevailing over the social sciences topics encompassing all priorities, e.g. in HORIZON 2020 funded by €77, 03 billion: 1.Industry driven: Strategic investments in key technologies, Support to innovative companies, 2. Researchers driven: Excellent science as the foundation of modern technologies, 3. Society driven: Concerns of citizens and society/EU policy objectives, Multidisciplinary collaborations. Being exposed to hands-on experience of multiple successful project applicants and project reviewers one could observe the significance of creating skilful project leadership to cover relevant project life phases: 1. Project proposal, 2. Project team comprising, 3. Project management, 4. Project results dissemination and 5. Visibility. Project management in Serbian higher education is prime skill also helping the internalization of the universities.


Theoretical optimization of ARC (antireflecting coating) for both, single and double ARC has been done in the order to obtain minimum reflectance on crystalline silicon surface. Experimental corroboration has been made with the deposition of a simple SiN/sub x/ (silicon nitride) and double SiN/sub x//SiO/sub 2/ (silicon nitride/silicon oxide) ARC on silicon substrates using PECVD (Plasma enhanced chemical vapor deposition) technique. Different refraction indexes were obtained by means of NH/sub 3/ flow adjustment. Reflection measurements as a function of wavelengths revealed some differences with theoretical calculations for both simple- and double-layer ARCs. We demonstrate how important is the ARC thickness for optical matching for single and double ARC. An analysis and discussions are made for a proper interpretation of the observed behavior.


A streamline upwind formulation is presented for the treatment of the advection terms in the general transport equation. The formulation is monotone and conservative and is based on the discontinuous nature of the advection mechanism. The results of there benchmark test cases for the full range of flow Peclet numbers are presented. The new formulation is shown to accurately model the advection phenomenon with significantly smaller numerical diffusion than the existing methods. The results are also free of all spatial oscillations. Considerable savings in computer storage and execution time have been achieved by employing the three-noded triangular element for which exact integrations exist. The formulation is straightforward and can be readily incorporated into any finite element code using the conventional Galerkin approach.


LKB1, originally considered a tumor suppressor, plays an important role in hepatocyte proliferation and liver regeneration. Mice lacking the methionine adenosyltransferase (MAT) gene MAT1A exhibit a chronic reduction in hepatic S‐adenosylmethionine (SAMe) levels, basal activation of LKB1, and spontaneous development of nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC). These results are relevant for human health because patients with liver cirrhosis, who are at risk to develop HCC, have a marked reduction in hepatic MAT1A expression and SAMe synthesis. In this study, we isolated a cell line (SAMe‐deficient [SAMe‐D]) from MAT1A knockout (MAT1A‐KO) mouse HCC to examine the role of LKB1 in the development of liver tumors derived from metabolic disorders. We found that LKB1 is required for cell survival in SAMe‐D cells. LKB1 regulates Akt‐mediated survival independent of phosphoinositide 3‐kinase, adenosine monophosphate protein–activated kinase (AMPK), and mammalian target of rapamycin complex (mTORC2). In addition, LKB1 controls the apoptotic response through phosphorylation and retention of p53 in the cytoplasm and the regulation of herpesvirus‐associated ubiquitin‐specific protease (HAUSP) and Hu antigen R (HuR) nucleocytoplasmic shuttling. We identified HAUSP as a target of HuR. Finally, we observed cytoplasmic staining of p53 and p‐LKB1(Ser428) in a NASH‐HCC animal model (from MAT1A‐KO mice) and in liver biopsies obtained from human HCC derived from both alcoholic steatohepatitis and NASH. Conclusion: The SAMe‐D cell line is a relevant model of HCC derived from NASH disease in which LKB1 is the principal conductor of a new regulatory mechanism and could be a practical tool for uncovering new therapeutic strategies. (HEPATOLOGY 2010)


PULSATILE ECHOENCEPHALOGRAPHY is a technique for detecting changes in intracranial structures. Previous reports have noted changes in the amplitude of echo pulsations with episodic flattening in the electroencephalogram1 and with other physiologic2 and pathologic3 conditions. Since these reports were published, we have screened approximately 30 normal subjects and 25 epileptic patients. When a single channel was used to record pulsatile echoes, the echogram revealed several alterations which seemed to follow K-complexes in the EEG4 and abnormal bursts of EEG activity. When we began to record echoes from more than one region simultaneously, it became obvious that the echo alterations are related to K-complexes and epileptic discharges. This paper presents the preliminary results of simultaneous EEG, echo, and blood pressure recordings, the last made by the indirect method.5 These recordings were made during several varieties of epileptic attacks and also during periods of auditory stimulation which evoked K-complexes. Normal subjects and patients with abnormal discharges were studied in the same manner, except that digital blood pressure was recorded only in the normal group.


This article explores the background of anatomical educational research. It draws together research and our own personal experiences to propose a best practice piece for novice researchers in anatomical education. The article explores the domains of both qualitative, and quantitative methods as applied to anatomy pedagogy. It takes into consideration validity and what might be undertaken to increase validity and reliability. The article explores how both qualitative and quantitative data can be analysed and recommends top tips including: Identify your research questions and theoretical framework. Map out how you are going to answer your research questions. Consider collaborating with like-minded researchers in other countries:
multi-centre studies have a better chance of getting published and carefully consider your target
journal and suggestions for peer review, taking into consideration individuals expertise and
potential conflicts of interests. This article is designed to be a guide to anyone starting
anatomical research or experienced researchers looking for new methods and ideas.


The effect of angiotensin (Ang)‐1–7 on dopamine, γ‐aminobutyric acid (GABA) and glutamate release in the striatum of the rat was examined using in vivo microdialysis. Ang‐(1–7) was administered locally in the striatum through the microdialysis probe. At a concentration of 100 µm, Ang‐(1–7) caused a significant increase in extracellular dopamine and GABA but had no effect on glutamate release. The Ang‐(1–7)‐induced dopamine release was blocked by EC33, an inhibitor of aminopeptidase A, an enzyme which converts Ang‐(1–7) into Ang‐(3–7), suggesting that this effect occurs after metabolism into Ang‐(3–7). Indeed, administration of Ang‐(3–7) (10–100 µm) into the striatum caused a more potent increase in the striatal dopamine release than Ang‐(1–7). Because Ang‐(3–7) is an inhibitor of insulin‐regulated aminopeptidase (IRAP) and because Ang IV, another IRAP inhibitor, also causes a concentration‐dependent increase in dopamine in the rat striatum, IRAP may be involved in this effect. In contrast, EC33 had no effect on the Ang‐(1–7)‐induced GABA increase but the GABA release was blocked by the putative AT1‐7 receptor antagonist A779 (0.1 µm) and by the nitric oxide synthase inhibitor L‐NAME (1 mm). These drugs could not block the effect of Ang‐(1–7) on the striatal dopamine release suggesting that only the observed effects on GABA release are mediated by the AT1‐7 receptor and/or are associated with a release of nitric oxide.


Texture analysis has remained a remarkably trendsetting and productive field of research in the last two decades. There has been much progress, but the impact of illumination changes on automated texture classification and segmentation has gained very less focus. Research work carried out in the field of texture identification frequently focuses on the identification of textures with intraclass changes including illumination, rotation, viewpoint and small scale variations. Consequently, variations in texture owing to modifications in scale constitute among the ones that are difficult to manage. In this research work, as the first step, the classification of textures due to vast changes in scale is studied. In order to deal with this problem, first the solution is introduced and then the scale changes are reduced based on the predominant patterns in the texture. Inspired by the challenges imposed by this issue, a novel swarm intelligence approach known as Ant Colony Optimization (ACO) algorithm is introduced for modifying the components in the hidden layers used during the network training, for the extraction of more useful semantic texture patterns.


In this paper we explore economic impact of promotion and realization of an electric vehicle society (EVS). More concretely, this paper emphasizes a CGE-modeling approach to evaluate the following issues: entire economic impacts of subsidies for promotion of an EVS, price reductions, a change of industrial structure towards an EVS and modal shift towards an EVS. Our simulation results demonstrate that after introducing 20% subsidies to five industries, which are electric vehicle (EV) manufacturing, EV transport, solar power, cogeneration, and other transport, the total industrial output and city GDP increase. A large growth rate is found in industries where subsidies are introduced. But non-ferrous metal industry is exceptional. It is interesting that decreasing proportions are found in oil and coal product, mining, heat supply and gasoline vehicles (GVs) transport industries. Moreover, all the commodity prices decrease due to subsidies. Hence, Toyohashi city's economy shows a direction where the demand for conventional vehicles and energy use are decreased, and conversely the demand for EVs and renewable energy are increased that displays a different lifestyle from the current one. For all these reasons, it is authors' opinion that EVS can really represent a realistic alternative society both in terms of economic development and CO2 emissions reduction. In this study therefore it is clear that modal shift occurs to EVS, and thus we suggest the promotion of new industrial structure for introducing an EVS in Toyohashi city, Japan. The proposed model can even be applied to the other cities in Japan and other countries in the world which are similar to this area.


The effect of random shooting of particles is considered on the basis of solution of the Schrodinger equation and in terms of the Wigner function. Two-particles description shows, in particular, that initial correlation leads to high velocities of particles. This could be a potential mechanism for obtaining energy. Evolution of the n-particle probability distribution is descibed analytically.


Foster's brewery at Yatala have developed a G2-based real-time Utilities Consumption Model (UCM) of its plant. The UCM is used to estimate the instantaneous load of key utilities at the brewery. The contributions of individual equipment to the load profile can be estimated providing an unprecedented level of transparency into areas that are (in a metered sense) unmeasured. A case study is included that demonstrates the application of the UCM for load identification for the extensive refrigeration system that is critical for the brewery operations.


Damages that flow from the failure to make payment timeously have recently been the subject of debates in the Supreme Court of Appeal (SCA). As a result thereof, a number of principles emanating from a creditor's right to claim interest have been formulated in a number of reported cases.


Pitch tracking is the ability to identify the frequency of a sound signal in real time. Being able to do this quickly and accurately has many uses across different areas of both speech recognition and music processing. In music, each note is determined by the frequency of its sound, so identifying frequencies digitally allows computer programs to identify notes. This has many applications, such as in digital tuners and in musical transcription. People with chromesthesia map sounds, such as musical notes, to colors. For example, an A on a piano might "sound" blue. These color mappings are involuntary, consistent, and unique, meaning the same note always gets mapped to the same color, and two people with chromesthesia would likely not have the same color mappings. In this project, I attempt to use monophonic pitch tracking to build an application that allows people to visualize the experience of having chromesthesia. The color mappings used in the application were obtained from a person with chromesthesia. The pitch tracking is handled by a convolutional neural network that operates on fast Fourier transforms of sound data, trained using examples from various instruments of all 88 musical notes on a piano.


This paper presents a design technique that combines the LQG performance with H/sup /spl infin// and passivity conditions for robustness. The controller is obtained by solving two standard algebraic Riccati equations and it may be viewed as an LQ regulator connected to a nonstandard observer. The well-known LQG controller is obtained as a particular case.<<ETX>>


Pregnancy is a time of dynamic physiological changes occurring as a continuous spectrum. Smoothed centile curves describe the distribution of measurements as a function of age. There has been no application of centile charts in pregnancy for haematological parameters.


One–step preparation of electrospun bimodal fibrous membrane based on single nozzle is the key to the efficient fabrication of high–performance air filter. However, the preparation mechanism of electrospun bimodal fibers at low conductivity solution system is not clear, and there is a lack of evaluation methods for the quality of bimodal nanofibers, which limits the applicability of single nozzle electrospinning and the preparation efficiency of electrospun bimodal fibers. Here, three electrospinning processes at low conductivity solution systems of polyamide–6 (PA6), PA6 blended PVP (PA6/PVP), and PA6 blended polyethylene oxide (PA6/PEO) were studied according to the rheological properties and the fluid electrics (i.e., zeta potential), and the quality of the prepared bimodal fibrous membrane was creatively evaluated by R value. Inhomogeneous phase separations of the electrospinning jet along the direction parallel (x–axis) or perpendicular (y–axis) to the electric field were responsible for the formation of bimodal fibers. In addition, for the same solution system, the R value had a positive correlation with the air filtration performance. This work will greatly enhance the applicability of one–step single nozzle electrospinning for the preparation of bimodal nanofibers, improve the preparation efficiency, and promote the development of high–performance air filter. © 2022 Elsevier Ltd


Sensor network system has been commercialized in the environmental monitoring of soil buildings, but there are problems of the lack of analysis model for data and network structure. The objectives of this research were: (i) the design and Installation of the sensor network for acquiring the soil building environmental data and (ii) multi-position temperature and moisture data acquisition and analysis. According to the requirements of data acquisition and analysis, the tree structure sensor network, sensor and communication protocol of the data acquisition was needed. The analysis and modeling was done after downloading the data according the results of the simulation experiment. By analyzing the temperature and moisture data model according to the simulated rainfall experiment, we have found that single position moisture content changing with time are basically identical with theoretical relations. It is proved that the design of this system meet the demands of the analysis of the temperature and moisture monitoring for soil building, and it has a high reliability.


THIS ARTICLE EXAMINES DEFINITIONS OF THE CONCEPT OF "CLIENTELISM" SEEKING FOR A UNIVERSAL DEFINITION. THE AUTHOR BEGINS BY CONSIDERING DIFFERENT SUB-TYPES OF CLIENTELISM THAT EXPLAIN THEIR CAPACITY TO ADAPT TO CHANGING CIRCUMSTANCES. SHE THEN EXTENDS THE CONCEPT TO CLIENTELAR POLITICAL PARTIES, THEIR FORMS OF ORGANIZATION AND THEIR STRATEGIES FOR WINNING ELECTIONS.


Abstract Consumer demands drive continuous developments in the production of horticultural and ornamental crops. In addition to improvements in quality and nutritional content, crop producers must supply an increased variety of products to a year-round market. The availability of many horticultural and ornamental crop products is dependent on the timing of reproductive development. The time at which many plants initiate sexual or vegetative reproduction is governed by a number of interacting environmental factors such as daylength, light quality and temperature. Artificial manipulation of the growing environment is therefore frequently used to ensure production meets retailers' marketing programs, a strategy which can often result in high energy costs. An alternative approach involves the manipulation of genes encoding proteins responsible for perceiving and transducing environmental stimuli, in particular, the genes encoding the phytochrome family of plant photoreceptors. Alterations in the expression of genes encoding phytochromes can modulate not only the timing of reproductive development, but also plant architecture. Such approaches can therefore be used to modulate a variety of phenotypic traits such as height, lateral branching and harvest yield, while enabling growers to tailor crop reproduction to their marketing needs. In this review, we will discuss examples of crop improvement using transgenic manipulation of phytochrome expression, along with benefits and disadvantages of such approaches.


Natural products from plant origin have been tested for their potential to develop viable components of plant parasitic nematode management strategies especially against Meloidogyne javanica . Different products based on P. harmala seed evaluated in pot experiments against M. javanica associated to Cucumis melo L. crop showed that when they are used as soil amendment in pre-planting, not only reduces densities of M. javanica in soil and crop damage to melon crops, but also improves significantly growth parameters except for the emulsified oil of P. harmala which proved a phytotoxic effect although it gave a complete suppression of M. javanica . The aqueous extract and the seeds powder are among the less phytotoxic substances, which are efficient against these pathogens. P. harmala -seed-based-products have a potential antinematodes effect against Meloidogyne javanica and can be used as component of an integrated management system to control this root knot nematode. Keywords: nematodes management, Peganum harmala ; extracts, organic amendment, Cucumis melo


Abstract The kinetics of polymerization of acrylamide (AA) initiated by the redox system V(III)(acac)3 -benzoyl peroxide (BPO) in DMF were investigated in the temperature range 40–45°C. A direct second-order reaction between V(III)(acac)3 and BPO was evident from the oxidation kinetics. Rates of polymerization varied as [AA]3/2 and [BPO]½ but were independent of [V(III)(acac)3]. Extensive reduction of primary radicals by V(III)(acac)3 with mutual termination of growing radicals accounts for the kinetics. Degrees of polymerization increased with increasing [AA] and decreased with increasing [BPO] but remained unchanged with variation in [V(III)(acac)3] as required by the mechanism proposed.


Abstract Although the non-intervention rule is often defended as a guarantee of international order, rigid adherence to it cannot be morally justified when governments commit or permit atrocities within their territory. In such cases, intervention is permissible and may even be obligatory. Drawing on the ideas of Rousseau, Kant, and to a lesser extent Hegel, this article examines the grounds of the argument for humanitarian intervention, demonstrating that intervention is in principle not only permissible but obligatory when considered philosophically. The right to intervene can be grounded on common morality, the protection of sovereignty and the coerciveness of justice. The duty to intervene rests on a respect for humanity and the conceptual relationship between rights and duties. Considering these two lines of argument shows that humanitarian intervention can be conceived as a duty that states can be reasonably required to perform.


Enantio-conversion of chiral mixtures has become an important research topic in chemical and biological fields. Here we propose a scheme for enantio-conversion of chiral mixtures via optical pumping based on a four-level model of chiral molecules composed of two chiral ground states and two achiral excited states, in which there exists a tunneling interaction between the chiral states. By eliminating one of the achiral excited states in the case of large detuning and well designing the detuning and coupling strengths of the electromagnetic fields, the induced indirect tunneling interaction between the chiral ground states can be cancelled with the direct tunneling interaction, and the induced indirect interaction between the left-handed chiral state and the remained achiral excited state can be cancelled with the direct one between them. Hence, the left-handed ground state is unchanged and the right-handed one can be excited to an achiral excited state, i.e., establishing chiral-state-selective excitations. By numerically calculating the populations of two chiral ground states, we find that the high enantiomeric excess can be achieved with almost only the left-handed ground state being populated. That means the high-efficiency enantio-conversion of chiral mixtures is realized under the combining effect of the system dissipation and the chiral-state-selective excitations.


The Sudanese Islamic patriarchal state has used its power to frame and define the legality of different livelihood strategies and to criminalise those who practice what the state refers to as, illegal livelihood strategies. For example, the Khartoum State Public Order Act (KSPOA), which was introduced in 1996 marginalised women's role in public life, praised their roles at domestic level and prevented them from working in certain occupations, such as restaurants, hotels and petrol satiations. Based on empirical research data, this paper investigates the patterns of the newly developed livelihoods strategies (legal and illegal) practiced by women and men at the camps and argues that internally displaced women at Al-Salam and Mayo displacement camps in Khartoum were able to develop a wide range of legal and illegal livelihood strategies. To protect their illegal livelihood, women were able to develop risk minimising and protection techniques, such as building personal relations with police officers, who would inform them when and where a kasha (rounding up and arresting) was most likely to happen, thus showing resilience and great ability to cope with the laws that tended to criminalise their livelihood activities On the other hand displaced men seemed less fortunate in developing new livelihood strategies. The paper also highlights the impact of these livelihoods on gender roles and relations by first exploring the 'adjustment period' during which gender roles and relations began to change and how men reacted to the change. Second, it highlights men's roles at the reproductive level, women's non reproductive roles and women and men


The purpose of this study was to examine the association between diet quality (utilizing Healthy Eating Index-2010 [HEI-2010] total scores) and fasting blood glucose in people living with human immunodeficiency virus (PLHIV). The associations between refined grains and total fruit consumption (HEI-2010 component scores) and fasting blood glucose were also explored.

 This was a cross-sectional analysis (N = 191) of an existing dataset from the Cardiovascular Assessment Risk Examination (CARE) study at Tufts Medical Center, Boston, MA between 2007 and 2013. It was hypothesized that there would be no association between diet quality and fasting blood glucose. Multiple linear regression was used to test the hypothesis adjusting for several a priori variables (age, race, sex, employment status, use of highly active antiretroviral therapy [HAART], living situation, body mass index, family history of type 2 diabetes [T2D] and year of enrollment).

 The mean age of the subjects was 41.1 years (SD = 7.1 years). Approximately half were white (50.8%, n = 97) and the majority were male (74.9%, n = 143). Subjects had a mean total HEI-2010 score of 49.3 out of 100 possible points with a range of 10–88 points. This is indicative of poor diet quality in this sample of PLHIV. Total protein foods and refined grains represented the component scores with the highest median scores (5.0 out of 5 possible points and 7.6 out of 10 possible points, respectively). Components with low median scores were total fruit (1.6 out of 5 possible points), whole fruit (1.4 out of 5 possible points), greens & beans (0.9 out of 5 possible points) and whole grains (1.5 out of 10 possible points). No significant associations were found between total HEI-2010 score and fasting blood glucose. No significant associations were found between the refined grains HEI-2010 component score or total fruit HEI-2010 component score and fasting blood glucose.

 Overall diet quality was low in this study and the hypothesis of no association between diet quality and fasting blood glucose was supported. Additional studies are needed to determine the relationship between diet quality and fasting blood glucose in PLHIV and how to improve diet quality in this population.

 The CARE study was supported by the National Institutes of Health (R01HL065947).


This paper introduces the design of a belt tension measuring tool and its application research. The tool is designed to be very handy and universal. This measuring tool has been successfully used for belt tension measuring and control in engine assembly line.


This research paper is interested in introducing a new methodological approach to evaluate a joint-venture negotiation between two players (or groups) respectively. Hence, this new methodological approach is entitled "The Joint-Venture Negotiation Box (JVNBox)." The primary objective of the JVN-Box is to calculate a suitable point of balance between two players for the generation of favorable conditions in a joint venture. Subsequently, the success of any joint-venture according to this research depends on the effort to work hard by the weak player and sacrifice welfare from the stronger player. In the Beginning, this study assumes that different players need to agree with some initial talks. In fact, both players can start a formal discussion to find the suitable point of balance in the process to consolidate a joint-venture. Nevertheless, the division between players always depends on the opportunity cost and incentives in the process of negotiation.


In this paper we show a new geometric interpretation of the hexagonal and triangular grids. They can be considered as the sets of points of one (see (I. Her, 1995)), respectively two plane(s) in Z/sup 3/. By this approach we can build up a whole family of triangular grids (the so called n-planes triangular grids). The hexagonal and triangular grids are the first two members of this family, moreover, they are duals of each other. We investigate the three-planes grid, the third member of the family, and its dual in detail. We show that for n /spl ges/ 4 on, the n-planes triangular grids are non-planar.


Example discloses a method for obtaining super-resolution image acquisition apparatus according to the present application and in which a super-resolution image acquisition method comprising: determining whether any two adjacent cameras of the camera array sensor an image of each zone to be adjusted , respective logical sub-pixel pixel-level target offset distance, each of said zone to be adjusted for the image sensor corresponding to the imaging area of the first region, respectively, said first region of said scene be taken at least partially; according to the said target sub-pixel level of the pixel shift distance adjusting each camera array image sensor camera distribution; acquiring images to be taken are based on the scene after the adjustment by the cameras; obtaining the respective images to be taken according to the acquired a super-resolution image of the scene. Example improve image quality super-resolution sub-images in the first image region corresponding to the present application.


An experimental study was carried out to investigate the convective heat-transfer characteristics of singlephase water in the self-designed device with small bilaterally-heated annular channel under the condition of fully developed flow.By measuring the temperature with thermocouples and the flow velocity with flowmeters,the relationship between heat flux,flow velocity and convective heat-transfer coefficient was investigated at the different heat fluxes.The results show that when the outer or inner wall is heated separately,the convective heat-transfer coefficient of the wall increases with the increase of heat flux;and keeping the heat-flux,the convective heattransfer coefficient of the inner wall increases with the increase of water flow,the outer wall does not change significantly;when the outer and inner walls are heated together,the convective heat-transfer coefficient of the inner wall reduces first,and then increases,and the outer wall keeps increasing.


The railway traction industry is a field that is under constant development. As the technologymoves forward, so does the demands from customers and requirements that are needed to befulfilled. A tr ...


ABSTRACT: Data from 66 entry‐level physical therapy students who completed two computer‐based patient management problems in a physical agents class were used to test students' use of the patient management process and to determine student acceptance and cost of such a project. We also studied the relationship between students' scores on the problems and their opinions about computers, their experience with computers, and their previous clinical experience to see whether these variables affected students' scores. Scores indicated a good command of the patient management process. Students' attitudes toward the project were positive. The cost of the project was based primarily on the time involved in the development of the programs. The cost per student was $17.61. Performance on problems did not correlate significantly with students' opinions about the use of computers in physical therapy, their experience with computers, their familiarity with a keyboard, or their previous clinical experience. These patient management problems were useful, well‐accepted, and worth the initial costs of development and implementation.


Insulation protection can be provided by metal jacketing, mastic coatings, or a combination of both, depending on the application, service, and economics.


Introduction. CsA nephrotoxicity is an important cause of chronic allograft dysfunction. Clinical information concerning the impact of very early CsA dose reduction in kidney transplant recipients is limited. The objective of this study is to determine the long term outcomes of very early CsA dose reduction. This is synchronized with de novo everolimus and low dose corticosteroid therapy. Material and method. De novo kidney transplant recipients are prospectively investigated with informed consent. All received CsA (target C0 250350 ng/ml) and prednisolone as initial therapy. CsA dosage is reduced by 50 % at day 7th post transplantation. Everolimus is concomitantly started at the day of CsA reduction with a target trough level of 3-8 ng/ml. After nadir serum creatinine is achieved, CsA is gradually reduced to maintain C0 at 50-100 ng/ml. Full pharmacokinetic studies of everolimus and CsA was studied at the period of 4-8 weeks after CsA reduction. Ten blood samples of everolimus and CsA level are drawn ( predose, 0.5, 1, 1.5, 2, 3, 4, 6, 9 and 12 hours). Primary end point is patient and graft survival rate. Secondary end point is renal function as determined by MDRD GFR. No patient receive induction therapy. Results. There are 10 patients being enrolled (8 living related and 2 deceased donors). Four patients have diabetes mellitus as the cause of ESRD. Mean HLA mismatch is 2.4 ± 1.07 antigens. Mean follow up duration is 51.2 ± 3.45 months. Nadir serum creatinine is 1.03 ± 0.33 mg/dl. Mean initial GFR is 97.97± 23.36 ml/min. At the time of pharmacokinetic study, mean trough everolimus is 4.95±1.56 ng/ml (range 3.06-7.56). Mean Cmax of everolimus is 15.4±4.6 ng/ml. Time to Cmax of everolimus is 1.5±0.3 hr. Mean AUC of everolimus is 90.48±16.83 ng·hr/ml. Mean CsA trough level and AUC is 100.30±42.72 and 3449±1402 ng/ml. At last follow up, mean dose of CsA is 75 ± 24 mg/day, mean trough CsA level is 85±29 ng/ml, mean dose of everolimus is 1.275 ± 0.25 mg/day, mean everolimus level is 6.68± 2.0 ng/ml, mean serum creatinine is 1.2 ± 0.43 mg/dl. GFR at 1 year, 3 year and last follow up is 82 ± 25, 80 ± 21 and 80 ± 25 ml/min. Serum cholesterol and triglyceride change from 184±50 and 97±66 at base line to 225 ± 43 and 142 ± 74 mg/dl at last visit. Seventy percent of patients require lipid lowering drug by statins. Acute rejection occurs in one patient (10%) and is treated successfully by pulse methylprednisolone. One patient develops mild degree interstitial lung disease that requires everolimus dose reduction. Post transplant DM develops in three patients (30%). Recurrence Ig A nephropathy develops in two patient (20%). No patients have delay graft function, impair wound healing and lymphocele. Patient and graft survival is 100 %. Conclusion. Very early CsA dose reduction synchronized with de novo everolimus therapy is associated with good long term patient and graft survival in kidney transplant recipients. This intervention is associated with very good MDRD GFR at 4 years.


The synthesis and systematic evaluation of the influence of lateral mono‐, di‐ and tetra‐fluorination of the terminal phenyl ring on mesomorphic properties in seven novel series of suitably fluoro‐substituted 5‐n‐alkyl‐5′‐(4‐n‐decyloxyphenyl)‐2,2′‐bithienyls is reported. Compared with their non‐fluorinated parent counterparts, lateral fluorination eliminates high order smectic phases and reduces thermal stability, to reveal compounds exhibiting a selection of nematic, smectic A and smectic C phase types. As the number of fluoro‐substituents increases from one to two, mesophase thermal stability drops drastically; the disposition of the second fluoro‐substituent is important. Across‐axis disposition is more detrimental than along‐axis. However, complete fluorination does not destroy mesophase formation. Indeed, tetrafluorophenyl compounds are more stable than certain 3,5‐ and 2,6‐difluoro compunds. The extrapolated birefringence for members of a series of 5‐n‐alkyl‐5′‐(2,3‐difluoro‐4‐n‐decyloxyphenyl)‐2,2′‐bithienyls is approximately 0.21.


Objective To eliminating the effects of negative psychological factor of bladder tumor patients through the effective nursing intervention.Methods Implements the whole course,non-slit responsibility system nursing to 56 bladder tumor patients.Results All patients are able to cooperate with the treatment actively.Conclusions The effective nursing intervention in the course of treatment acts is a key role after surgical treatment of urinary bladder tumor.


Bullying at school is a type of violent and aggressive behaviour among students, which occurs in many countries around the world and, in recent years, keeps increasing and causing problems for students, their families and the school itself Rigby [1] . Also, school bullying has significant long-term effects even in adult life Rigby, Johnson [2]. Based on the premises that research has demonstrated a strong association between boredom proneness and various measures of aggression including physical and verbal aggression, anger, and hostility Fahlman et al. [3], Rupp [4], while taking the perspective of another person often leads to more compassionate perceptions and pro-social behaviour toward that person Myers [4], we examined whether boredom and interpersonal closeness predict bullying and victimization. Understanding the potentially complex relations among boredom and interpersonal closeness can have implications for the assessment and prevention of bullying and victimization at school. Bullying


Opinions of Washington state dentists on the use of expanded duties for dental auxiliaries were surveyed in a questionnaire mailed six months after the state's dental law was amended. Fifty-five percent of the dentist population responded. The percentage of positive responses to the use of expanded duties for dental assistants and hygienists decreased with the increasing age of dentists surveyed. Results of the survey indicate that opinions of the dentists were not related to the size of the community in which they practice. Dentists who were least busy most strongly favored expanded duties for both auxiliaries.


This paper puts forward an l-syntactic approach (see Hale a Keyser 1993 and subsequent work) to VP adjuncts/modifiers, which are analyzed as PPs undergoing Merge with the VP —as high applicatives , in Pylkkanen's (2008) sense—. The present proposal argues for a treatment where the merger of VPs and adjuncts gives rise to a Talmian Figure-Ground relation whereby VPs are interpreted as subjects (Figures), and adjuncts as predicates (Grounds). If tenable, the analysis requires no additional mode of combination for adjuncts (pair Merge, predicate composition, etc), apart from Chomsky's (set) Merge. Given the nature of the matters to be discussed, the paper has the most general goal of reexamining the consequences of Chomsky's (2008) recent label-free conception of Bare Phrase Structure (BPS) for Hale a Keyser's l-syntax.


judged with a scoring system for the cosmetic results by an impartial, blinded surgical observer, and the mean score in each group was the same. The tissue adhesive in our trial was applied by practice nurses, who were already competent in suturing. They found that its use was easy to learn and it was a preferable option for many wounds. We think that tissue adhesives, when used appropriately (as outlined by Mr Watson and the manufacturers), are ideal for smaller casualty units or general practitioners and would therefore encourage the Department of Health to consider making them prescribable on an FP10 prescription, bearing in mind that they are indeed cheaper than suture materials. I hope that Mr Watson's study will stimulate a further review of these substances, for which there is a paucity of good published research.


Metronidazole (MNZ), a typical example of nitroimidazole antibiotics, is widely used in the treatment of infectious diseases caused by anaerobic bacteria. The degradation mechanism and kinetics of MNZ in the presence of HO• and SO4•− were studied using density functional theory (DFT). It was confirmed that both HO• and SO4•− easily added to the carbon atom bonded to the NO2 group in the MNZ molecule as the most feasible reaction channel. This study shows that subsequent reactions of the most important product (M-P) include the O2 addition, hydrogen abstraction and bond breakage mechanisms. The rate constants of HO• and SO4•−-initiated MNZ in the aqueous phase were calculated in the temperature range of 278–318 K. The total rate constants of MNZ with HO• and SO4•− were determined to be 8.52 × 109 and 1.69 × 109 M−1s−1 at 298 K, which were consistent with experimental values of (3.54 ± 0.42) × 109 and (2.74 ± 0.13) × 109 M−1s−1, respectively. The toxicity of MNZ and its degradation products to aquatic organisms has been predicted. The results proposed that the toxicity of the initial degradation product (M-P) was higher than that of MNZ. However, further degradation products of MNZ induced by HO• were not harmful to three aquatic organisms (fish, daphnia, and green algae). This study provides a comprehensive theoretical basis for understanding the degradation behavior of MNZ.


OF THESIS ENTROPY OF ELECTROENCEPHALOGRAM (EEG) SIGNALS CHANGES WITH SLEEP STATE We hypothesized that temporal features of EEG are altered in sleep apnea subjects compared to normal subjects. The initial aim was to develop a measure to discriminate sleep stages in normals. The longer-term goal was to apply these methods to identify differences in EEG activity in sleep apnea subjects from normals. We analyzed the C3A2 EEG and an electrooculogram (EOG) recorded from 9 normal adults awake and in rapid eye movement (REM) and non-REM sleep. The EEG signals were filtered to remove EOG contamination. Two measures of the irregularity of EEG signals, Sample Entropy (SpEn) and Tsallis Entropy, were evaluated for their ability to discriminate sleep stages. SpEn changes with sleep state, being largest in Wake. Stage 3/4 had the smallest SpEn (0.57±0.11) normalized to Wake values, followed by Stage 2 (0.72±0.09), REM (0.75±0.1) and Stage 1 (0.89±0.05). This pattern was consistent in all the polysomnogram records analyzed. Similar pattern was observed in lead O1A2 as well. We conclude that SpEn may be useful as part of a montage for assessing sleep state. We analyzed data from sleep apnea subjects having obstructive and central apnea events and have made some preliminary observations; the SpEn values were more similar across sleep stages and also high correlation with oxygen saturation was observed.


Prolonged lifting may be associated with an incrase injury risk due to fatigued muscles being less capable of reacting to any perturbations that occur during a lift. Repetitive muscle use leads to reduced functional capacity, known as fatigue. In lower force tasks, fatigue is an ongoing process which may result in increased perceived effort and a reduction in the maximal force generating capacity of a muscle [1]. This study investigated the neuromuscular changes in a general and two local fatiguing lifting protocols.


The present invention relates to one kind of coordinate measurement on a workpiece coordinate measuring device used for the method of the coordinate measuring device having a probe (4), the probe comprising a probe (3) and associated with a probe detection sensor (7), when the probe needle detection sensor contact workpiece detection signal (23), determines the size value indicating a position of the probe when it contacts the workpiece by the probe signal, wherein the probe further comprises an acceleration sensor (65), the acceleration sensor generating an acceleration signal when the probe acceleration (67), wherein the detection signal and the acceleration signal is fed to a control and evaluation unit (68) for analysis, and wherein the control and analysis unit determines the size of the value, so that the detection signal is determined by subtracting the signals to each other and an acceleration signal analysis (69), and analyzes the signal using only the determined value of the position indicating the size of the probe upon contact with the workpiece. The present invention further relates to a corresponding coordinate measuring device.


Objective:To investigate the levels of IL-18 and IL-12 in peripheral blood of normal pregnant and in pregnancy-induced hypertension patients,and to explore the role of Th1/Th2 cytokines in the pathogenesis of pre-eclampsia.Methods:34 cases pre-eclampsia patients pregnant 20 weeks(mild pre-eclampsia 15 cases and severe pre-eclampsia 19 cases),normal pregnancy group 32 cases,non-pregnant controls 16 cases.The peripheral blood was tested by flow cytometry,selected the lymphocytes with highest expression of CD28 as experimental subject.IL-12 and IL-18 were detected by ELISA Th1/Th2 ratios in PBMC was detected by flow cytonetry.Results:IL-12 in normal pregnancy group,pregnancy-induced hypertension group and non-pregnant group were significant difference(P0.001).IL-18 in mild pre-eclampsia cases,severely pre-eclampsia cases and normal pregnancy subjects had no significant difference(P0.05).While the ratios of IL-18/IL-12 in normal pregnancy group and pregnancy-induced hypertension group had significant difference(P0.000 1).Thl/Th2 ratios were negatively correlated with the ratios of IL-18/IL-12.Conclusion:The ratios of IL-18/IL-12 were significantly higher in normal pregnant group than pregnancy-induced hypertension group,and Th1/Th2 ratios were negatively correlated with the ratios of IL-18/IL-12.


Euphorbia species possess pharmacological properties that have been widely used for medical purposes worldwide. In this paper, three plants belonging to the Euphorbia genus growing in North-East of Algeria were studied. The phenolic contents were identified using LC-MS, while the fatty acid composition of their fixed oils was determined with GC-MS. The quantification of the total condensed tannins and the leaves' entire anthocyanin content were performed using photometric methods. The main constituents of the polyphenolic compounds identified by LC-MS were ascorbic, chlorogenic, and ellagic acids. The oil yield of the seeds of E. terracina, E. biumbellata, and E. dendroides was 17.48%, 18.5%, and 20.05%, respectively. Quantitative analyses of these oils using GC-MS showed variations in the species' fatty acid constituents' concentrations and compositions. Besides, the phytochemical screening results showed that E. terracina possessed a high amount of tannin and anthocyanin content compared with other studied plants.


The context of this article is the programme to develop monoidal bicategories with a feedback operation as an algebra of processes, with applications to concurrency theory. The objective here is to study reachability, minimization and minimal realization in these bicategories. In this setting the automata are 1-cells, in contrast with previous studies where they appeared as objects. As a consequence, we are able to study the relation of minimization and minimal realization to serial composition of automata using (co)lax (co)monads. We are led to define suitable behaviour categories and prove minimal realization theorems that extend classical results.


The University of Arizona Cooperative Extension's efforts in rangeland management bring together private ranchers, public land managers, and Extension agents and specialists to promote rangeland health, conservation, and preserve productivity and profitability for land users, basing management decisions on best available science. University of Arizona Cooperative Extension Specialists were involved in a project to address proposed changes to a rancher's grazing allotment permit on federal land in Northern Arizona.


While in vitro studies suggest an important role for carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in infection by various human-restricted pathogens, in vivo evidence supporting this role has been lacking, largely because the bacterial adhesins involved do not bind to murine-derived CEACAM1. Bookwalter et al. (p. 48–55) show that the outer membrane protein P5-homologous adhesin expressed by nontypeable Haemophilus influenzae (NTHI), essential for colonization of the chinchilla nasopharynx and infection of the middle ear, binds to the chinchilla homologue of CEACAM1. Further, CEACAM1-specific antibodies effectively blocked nasopharyngeal colonization by NTHI. These findings provide the first demonstration of a role for CEACAM receptor binding by any bacterial pathogen in vivo.


This study aims to find out the technological content knowledge profile of Mathematics Education Students of Teacher Training and Education Faculty, Universitas Muhammadiyah Sukabumi who have completed courses in Mathematics Capita Selecta III. The research method used is descriptive with quantitative approach. Data is collected by survey method, using a questionnaire instrument whose statement is based on the component of technological content knowledge. The results showed that students' technological content knowledge was in a good category with an means 3.52 which means that students of Mathematics Education understood how to integrate technology and material in learning school mathematics.


When ever the Planning Commission of India releases the poverty data, that data is being criticised by experts and economists. The main criticism is underestimation of poverty especially in rural India by the Planning Commission. This paper focuses on that criticism and compares the Indian Planning Commission's 2004-05 rural poverty data with the India's 2400 kcal poverty norms, World Bank's US $1.08 poverty concept and Asian Development Bank's US $1.35 poverty concept.


A method for producing benzaldehyde is provided. Benzaldehyde is produced from L-phenylalanine or a carbon source by using microorganism(s) having amino acid deaminase, 4-hydroxymandelate synthase, (S)-mandelate dehydrogenase, and benzoylformate decarboxylase.


Most patients with type 2 diabetes are sedentary despite the clear benefit of regular physical activity, including better glucose control and improvement in quality of life (1). Smartphones could potentially improve patient care by continual communication with patients and sensors that quantify patient behavior (2). Nevertheless, the use of personalized messages that take into account the actual behavior of patients and learn to reinforce it has not yet been reported.

We provided a total of 27 patients with type 2 diabetes who did not perform regular physical activity prior to recruitment with a pedometer installed on their personal smartphones and a personal plan for physical activity. Patients were randomized into a control group ( n = 7) and a treatment group ( n = 20), and received text messages (via the Short Message Service [SMS] on the smartphone) one to seven times a week to encourage physical activity. In the treatment group, the messages consisted …


The paper highlights the outcome of site response studies undertaken around Union Territory of Chandigarh, based on geotechnical approach. Twenty-four boreholes were drilled down to 30 m depth in order to determine the variation in the geotechnical properties of the geological units present around Chandigarh. Standard Penetration Test (SPT), as per BIS Code, was conducted in all the boreholes for determination of N values of the subsurface geological units at 1 to 3 m intervals. Shear Wave Velocities of the subsurface layers were computed based on the empirical relation. The average shear wave velocity of the sediments down to 30 m depth at different sites around Chandigarh Urban Centre varies from less than 216 to 305 m/s. The predominant frequencies at which the seismic waves are expected to resonate in the soil column of 30 m depth were also computed using frequency-shear wave velocity relationship. Based on the analysis of the geotechnical properties of subsurface soil samples, their disposition with respect to each other and also with ground water table conditions liquefaction potential around Union Territory has also been assessed.


The radical methods of the inward prayer recommended by Jesus, «go into your room», «shut the door», and finally, «pray to your Father who is in secret […] and who sees in secret», neither practically teaches how to enter into the inner chamber nor how to shut the door, but constructs a space, which is left to the disciples for further praxis. The contemplative practice of the nēpsis (mindfulness) found in the masters of the Philokalia explores the unexplained praxis of the skills, for of closing the doors, in order to prevail upon the mental riots, when one wants to pray and reach the state of stillness and contemplation of God. This study on the hermeneutical reading of watchfulness, in the Parable of the Ten Virgins, and the Philokalia, discloses the unique and the rich heritage of the Christian mindfulness meditation.


In this paper, we present a compact wideband diplexer based on the low temperature co-fired ceramic technology. To realize wide passbands and a compact size, a new design method uses multilayer inductors. This method can also eliminate the matching circuits between a common port and wideband bandpass filters. Its performance has been simulated and optimized by the finite element analysis. The diplexer can separate a low-frequency band (0.9–1.8 GHz) and a high-frequency band (2.4–4.5 GHz). It achieves wide passbands and a very compact size (5.0×3.0×0.552 mm3).


In mammals, melatonin receptors MT1 and MT2 are high-affinity G protein–coupled receptors and are thought to be involved in the integration of the melatonin signaling throughout the brain and periphery. In the present study, we describe a new melatonin binding site, named MTx, with a peculiar pharmacological profile. This site had a low affinity for 2-[125I]-melatonin in saturation assays in hypothalamus and retina (pKD = 9.13 ± 0.05 and Bmax = 1.12 ± 0.11 fmol/mg protein, and pKD = 8.81 ± 0.50 and Bmax = 7.65 ± 2.64 fmol/mg protein, respectively) and a very high affinity in competition assays for melatonin (pKi = 13.08 ± 0.18) and other endogenous compounds. Using autoradiography, we showed a preferential localization of the MTx in periventricular areas of the sheep brain, with a density 3–8 times higher than those observed for ovine MT1. Additionally, using a set of well characterized ligands, we showed that this site did not correspond to any of the following receptors: MT1, MT2, MT3, D1, D2, noradrenergic, and 5-HT2. Based on its affinity for melatonin, MTx did not seem to be implicated in the integration of cerebral melatonin concentration variations since they were saturating for MTx. Nevertheless, it remained of prime importance because of its periventricular distribution, which was in close contact with the cerebrospinal fluid, and its peculiar pharmacological profile responding to both melatoninergic and serotoninergic compounds. SIGNIFICANCE STATEMENT Herein a putative new melatonin binding site is described in sheep brain parts in close contact with the third ventricle. The characteristics of the pharmacological profile of this site is different from anything previously reported in the literature. The present work forms the basis of future full pharmacological characterization.


bolic disease and pulmonary hypertension by mechanisms that are not yet clear (although secondary localized fibrosis has been postulated in chronic thromboembolic pulmonary hypertension) [2– 4] . Finally, P-wave dispersion (independent of lung function) can occur as an early phenomenon in pulmonary hypertension in COPD, causing atrial arrhythmias. Pulmonary hypertension can also result in similar atrial arrhythmias without right atrial dilatation. Both of these sequelae could potentially lead to an increase in SGRQ score [5, 6] . Can the authors exclude these potential confounding factors as an explanation for at least part of the spirometric and SGRQ-based decline? Did patients undergo electrocardiography, Holter monitoring, echocardiography and CT pulmonary angiography? Dear Editor, Kim et al. [1] report the potential predictive value of exertional desaturation in chronic obstructive pulmonary disease (COPD) patients for decline in lung function. There was no noted difference in exacerbations to account for the decline in lung function. The desaturator group had a lower baseline gas transfer, resting saturation, FEV 1 and body mass index and a higher BODE index and St George's Respiratory Questionnaire (SGRQ) score. Therefore, two of the other diagnostic possibilities to consider in the desaturator group would be pulmonary embolic disease and secondary pulmonary hypertension (with or without secondary atrial arrhythmias or P-wave dispersion), which would not be apparent on the volumetric CT scan unless the emboli were large and proximal or the pulmonary hypertension was severe, as suggested by the ratio of the pulmonary artery to the aorta. Pulmonary embolic disease or secondary pulmonary hypertension due to COPD might partially account for the lower baseline gas transfer, elevated SGRQ score and even the spirometric decline. Restrictive ventilator defects with reduction in both FEV 1 and forced vital capacity have been reported in pulmonary emPublished online: February 13, 2014


Significance Statement Differences in survival between Black and White patients with childhood-onset kidney failure are recognized, but the impact of lifelong racial disparities in kidney transplantation on survival is not well characterized. In a 30-year observational cohort study of 28,337 children that extends into young adulthood, Black patients had a 45% higher risk of death, a 31% lower rate of first transplant, and a 39% lower rate of second transplant. Black patients had fewer living donor transplants than White patients. Children and young adults are likely to require more than one transplant during their lifetime, yet even after their first transplant Black patients received 11% fewer total lifetime transplants than White patients. Transplants failed earlier for Black patients after the first and second transplant. These combined disparities resulted in Black patients spending 24% less time being treated for kidney failure with a transplant than White patients. We estimate that 35% of excess deaths in Black patients with ESKD beginning in childhood would be prevented if their time with a transplant was the same as among White patients. Increasing kidney transplant rates and improving allograft survival for Black children and young adults has the potential to help close the survival gap. Background The role of kidney transplantation in differential survival in Black and White patients with childhood-onset kidney failure is unexplored. Methods We analyzed 30-year cohort data of children beginning RRT before 18 years of age between January 1980 and December 2017 (n=28,337) in the US Renal Data System. Cox regression identified transplant factors associated with survival by race. The survival mediational g-formula estimated the excess mortality among Black patients that could be eliminated if an intervention equalized their time with a transplant to that of White patients. Results Black children comprised 24% of the cohort and their crude 30-year survival was 39% compared with 57% for White children (log rank P<0.001). Black children had 45% higher risk of death (adjusted hazard ratio [aHR], 1.45; 95% confidence interval [95% CI], 1.36 to 1.54), 31% lower incidence of first transplant (aHR, 0.69; 95% CI, 0.67 to 0.72), and 39% lower incidence of second transplant (aHR, 0.61; 95% CI, 0.57 to 0.65). Children and young adults are likely to require multiple transplants, yet even after their first transplant, Black patients had 11% fewer total transplants (adjusted incidence rate ratio [aIRR], 0.89; 95% CI, 0.86 to 0.92). In Black patients, grafts failed earlier after first and second transplants. Overall, Black patients spent 24% less of their RRT time with a transplant than did White patients (aIRR, 0.76; 95% CI, 0.74 to 0.78). Transplantation compared with dialysis strongly protected against death (aHR, 0.28; 95% CI, 0.16 to 0.48) by time-varying analysis. Mediation analyses estimated that equalizing transplant duration could prevent 35% (P<0.001) of excess deaths in Black patients. Conclusions Equalizing time with a functioning transplant for Black patients may equalize survival of childhood-onset ESKD with White patients.


LLE Review, Volume 92 181 Stimulated Raman scattering (SRS), an instability in which light is scattered by and amplifies electron plasma waves, has long been a concern in laser-fusion research because of its potential to reduce absorption and implosion efficiency. This concern is enhanced by the unsatisfactory state of the theory, particularly in accounting for the prevalence of anomalous SRS—scattering from plasma waves that according to conventional theory should be very heavily Landau damped.1–5 Furthermore, scattering from waves satisfying the electron-acoustic (EA) dispersion relation (see below), which according to conventional theory should also be very heavily damped, has recently been identified.2,4 These observations imply that Landau damping in laser-produced plasmas is often lower by an order of magnitude than would be predicted by the conventional linear theory of waves in a Maxwellian plasma.5


Previous grammar checkers support learners' writing by indicating errors and correct usages. However, until the lack of linguistic knowledge that caused the errors is corrected, similar errors will recur. This study developed a learner corpus by annotating tags for the causes of article errors, and analyzed the distribution of error-cause tags with the aim of developing a technique to provide feedback on the causes of grammatical errors. The results suggested the necessity to extend error-cause tags, and the preferable extension conditions based on writing type and proficiency level.


Abundant Mo, Ni, U ore deposit within the black shales at the bottom of Cambrian in Zunyi, Guizhou Province was considered hydrothermal sediment. According to the lithological and mineral feature and geochemical characters of the black shales in Xiaozhu area, Zunyi County, writers suggest that Mo, Ni, U ore deposits belong to hydrothermal vent sediment. Major proofs are asfollows:(1) Abundant pyrite, capillose, molybdenite, and ullmannite, chalcopyrite, sphalerite, barite, quartz, gypsum. (2) Abundant syn-depositional gravel fragments, which are composed of black carbonaceous body and fragmental pyrite, capillose, molybdenite, and accumulated into beds. Thefragments show the features of rend-form and resorption form, orebeds show the globular structure, basin-shaped and pillow structure, belonging to sea floor hydrothermal vent sediment. (3)Si-isotope, Sm-isotope, Re-Os ratio value, Th/Sc and Th/U ratio value showing mantle materialintrusion. (4) Carbonate in the black shales has sharp negative carbon isotopic value. (5)Abundant Mo, As, Se, Re and Tl elements are typical gas-migration element, and Mo is typical high temperature gas-migration element, which hint that volcano eruptions happened at the beginning of Cambrian. Active ultrabasic magma supplies abundant Ni, U, Au, Ag, PGE elements. An abundant, but low diversity biota, including large-type spongia, bivalve, Cyanophyta, and a small amount of larger-type worm, similar to modern hydrothermal vent community in the pacific. Therefore,writers suggest that the biota in Mo, Ni, U ore deposit within the black rock series in Xiaozhu, Zunyi County, Guizhou Province is relative to hydrothermal vent community. The new discoveryis important for us to study the Cambrian explosion and the palaeoecology of early life.


The patient whose case of xeroderma pigmentosum is reported in this paper presented an unusual clinical picture, and the diagnosis was definitely established only after histopathologic studies had been made. Certain histopathologic features which we consider diagnostic of the disease will be emphasized. Finally, some of the clinical and histopathologic features in the case will be considered briefly in connection with certain etiologic concepts regarding the disease. The clinical picture of the disease in its various stages, together with a review of the literature, is adequately given in modern textbooks of dermatology and will not be considered further.1 REPORT OF A CASE History.—A widow, aged 32, came to the Mayo Clinic in September, 1929, because of dysmenorrhea. She was born in Colorado, and was of Scotch, Irish and German descent. There was no consanguinity of the parents, and they were living and well. Two brothers had died


This work presents the thermal field computation of a wire getting a laser supported material cladding. We present two complementary models, based on finite volume approaches. First, we present a one dimensional model in which moving of the wire is integrated by mean of an advection term in the heat diffusion equation. It gives the mean temperature variation along the wire An analytical solution of this problem is also given. Secondly, a three-dimensional model gives the complete thermal field. These two models are confronted with experiments. The result of the first one is compared to a maximum mean temperature measuring. The second is validated by comparison with microphotography of the melted zone, and in-section micro-hardness measurements.


From two aspects of before being permitted to teach and after being permitted to teach,this paper discusses the approaches for cultivating English teachers'professionalism in order to provide some helps for English teachers to improve their professionalism.


Significance In addition to generating forces and reacting to mechanical cues, tissues are capable of actively pumping fluid and creating electric current. In this work, we examine how a hydraulic or electrical perturbation, imposed, for instance, by a drain of micrometric diameter, can be used to perturb tissue growth. We address this issue in a continuum description of a spherical cell assembly that includes the mechanical, electrical, and hydraulic properties of the tissue. This approach allows us to discuss and quantify the effect of electrohydraulic perturbations on the long-time states of the tissue. We highlight that a moderate external pumping or electric current can drive a proliferating spheroid to decay. We propose that this could have applications in medicine. We use a theoretical approach to examine the effect of a radial fluid flow or electric current on the growth and homeostasis of a cell spheroid. Such conditions may be generated by a drain of micrometric diameter. To perform this analysis, we describe the tissue as a continuum. We include active mechanical, electric, and hydraulic components in the tissue material properties. We consider a spherical geometry and study the effect of the drain on the dynamics of the cell aggregate. We show that a steady fluid flow or electric current imposed by the drain could be able to significantly change the spheroid long-time state. In particular, our work suggests that a growing spheroid can systematically be driven to a shrinking state if an appropriate external field is applied. Order-of-magnitude estimates suggest that such fields are of the order of the indigenous ones. Similarities and differences with the case of tumors and embryo development are briefly discussed.


A high caloric regimen causes metabolic syndrome, which is a pre‐requisite for type 2 diabetes mellitus, and increases the risk for cardiovascular disease. Both metabolic syndrome and diabetes induce a common cardiac phenotype known as metabolic cardiomyopathy with an early onset as diastolic dysfunction that may progress to systolic dysfunction and congestive heart failure.


In the mid-eighteenth century the confluence of Enlightenment scientism and modernizing demands of the States gave rise to a radical turn in the cartographic representation of territories and cities. An "intelligentsia" composed by scientists, engineers, geographers, surveyors, etc. produced in less than fifty years many examples of this new way of looking at the world that embodied perfectly the Kantian "Sapere Aude!" This article attempts to outline, through the analysis of some paradigmatic cases, the nature of Enlightenment urban maps as a product of the requirement of a certain knowledge of the environment physiognomy, and as the cartographic expression of the ideas of "progress, public happiness, and wealth of the nation", as well as the utopic face of Enlightenment thinking.


OBJECTIVE
Many students have paid employment while studying. In the Netherlands, the Individual Health Care Professions Act (IHCP Act) allows dental hygiene students to work under certain conditions in a dental practice. The aim of the study was to determine how many dental hygiene students have part-time job employment in dental practice and which professional tasks they carry out. We also asked the dental hygiene students their opinion of the IHCP Act.

METHODS
All the enrolled dental hygiene students (n = 341) at a School of Health in the Netherlands received a questionnaire by email.

RESULTS
The response was 52% (176 students). Of the responding students, 75% had paid employment in addition to their study. A proportion of the students (35%) worked in a dental practice. The median number of hours worked per week was eight. Study year, age and prior education were positively related to working part-time in dental practice. Activities frequently performed were giving oral hygiene instruction, fluoride applications, scaling and root planning, providing chair side assistance and giving local anaesthesia. Although the self-reported knowledge about the IHCP Act was high, almost half of the students expressed the need for more detailed legal information.

CONCLUSIONS
Many dental hygiene students work in a dental practice, taking over a number of tasks usually performed by the dentist. More information in the dental hygiene curriculum about the requirements of the IHCP Act seems desirable.


Aim: This study aimed to evaluate the shear bond strength (SBS) values of a self-cured adhesive system to calcium silicate and calcium hydroxide-based pulp capping materials.
Materials and Methods: Cylinder shaped cavities (2x5 mm) were prepared in the middle of 120 acrylic blocks. Three pulp capping materials (Biodentine, Theracal LC, Kerr Life) were placed into the cavities. Single Bond 2 (SB2), Clearfil SE Bond (CSB), Clearfil Universal Bond (CUB), Tokuyama Self-cured Universal Bond (TUB) were applied for each pulp capping material (n=10). After composite resin cylinders were prepared, SBS tests were carried out. Data and failure modes were analysed using two-way ANOVA, Tamhane's T2 (p≤0.05) and stereomicroscope, respectively.
Results: Theracal LC, showed the highest SBS values, and there was a statistically significant difference amongst pulp capping materials for all adhesives (p≤0.05). The lowest results were found in the Life+TUB (0.79±0.14), and the highest was Theracal LC+CSB (8.55±1.73). In Biodentine, all adhesive systems showed lower results than Theracal LC groups, whereas there was a statistically significant difference between SB2 and TUB compared to the Life.
Conclusion: If the self-curing universal adhesive system with less technical sensitivity and consuming less time will be used in vital pulp treatments, calcium silicate-based resin capping materials may be preferred.
Keywords: Biodentine; bond strength; pulp capping; self-cured universal adhesive; theracal LC


Haemophilia B is caused by a deficiency of coagulation factor IX (FIX) and characterized by bleeding in muscles and joints. In the perioperative setting, patients are treated with FIX replacement therapy to secure haemostasis. Targeting of specified FIX levels is challenging and requires frequent monitoring and adjustment of therapy.


Two difficulties face the student of the smaller Renaissance sculptures. Because of the relative unimportance of the works it is not easy to find literary evidence on which attributions may rest; the works being easily moveable and intrinsically of great value, they have traveled far from their original sources. The piece in a precious or semi-precious metal has about it a glamour due to some mystic subconscious memory from prehistoric days when man first learned to wrest from mother nature the secrets of metallurgy. The power of the active elements may be felt in a Chinese or Renaissance bronze flowing before our eyes in pleasurable vital forms. Because of this value and mystery connoisseurs have approached the subject with more aesthetic reverence than true analytic vision.


. This work considers the scheduling problem for Urban Air Mobility (UAM) vehicles travelling between origin-destination pairs with both hard and soft trip deadlines. Each route is described by a discrete probability distribution over trip completion times (or delay) and over inter-arrival times of requests (or demand) for the route along with a fixed hard or soft deadline. Soft deadlines carry a cost that is incurred when the deadline is missed. An online, safe scheduler is developed that ensures that hard deadlines are never missed and that average cost of missing soft deadlines is minimized. The system is modelled as a Markov Decision Process (MDP) and safe model based learning is used to find the probabilistic distributions over route delays and demand. Monte Carlo Tree Search (MCTS) Earliest Deadline First (EDF) is used to safely explore the learned models in an online fashion and develop a near-optimal non-preemptive scheduling policy. These results are compared with Value Iteration (VI) and MCTS (Random) scheduling solutions.


A select and distinguished group of physicists, chemists and biologists are the contributors to this book dedicated to Albert Szent-Gyorgyi. The expression of new and philosophical viewpoints projected towards the future of molecular biology is stressed throughout this volume. The book is divided into six sections, each devoted to one of the most intensive areas of current biochemical investigation. The first section deals with biochemical evolution. Calvin traces the work in his laboratory on photosynthetic mechanisms and suggests that heme and its oxidative function preceded the appearance of large amounts of oxygen in the earth's atmosphere produced by photosynthesis. Gaffron, using evidence from bacterial physiology, believes that respiratory mechanisms evolved from parts of an already existing complex photosynthetic apparatus. The existence of bioluminescence in the plant, animal and microbial world is attributed by McElroy and Seliger as a struggle for anaerobic existence of primitive organisms which led certain organisms to produce luciferase which rapidly removed molecular oxygen. The aerobic organisms came subsequently by gradual selection and evolution of electron transport processes. Rich has put forward the challenging idea that the transfer of genetic information and protein synthesis was carried out in primitive organisms by a stem polynucleotide molecule which was like an RNAlike polymer. The second section covers biochemical genetics. Ingram and Pauling independently focus our attention upon the differences in the hemoglobin molecule in the normal, fetal and certain disease states and discuss the problem of the existence and activation of "dormant genes." Ochoa summarizes the current concepts on the transmission of genetic information. The third section on biochemical catalysis opens with a chapter by Eyring, Jones and Spikes who pose the question of why the universally present L-amino acid protein helices and D-pentose nucleic acid helices evolved as code-containing entities and why D-amino acids are present in certain polypeptide antibiotics. Koshland considers the catalytic power of enzymes, Krebs discusses the relation of enzymic activity to cellular structure and Kornberg discusses the role of pyrophosphorylases in biosynthetic mechanisms. The fourth section, on molecular organization, concerns the semiconductor properties of biological systems such as the cytochrome systems, chloroplasts and retinal rods. The mitochondrion is considered as a biological transducer by Green while Lehninger outlines the role of the mitochondrion in the active transport of ions and the mechanical changes associated with the uptake and extrusion of water. F. 0. Schmitt examines the various promising areas of research using the methods of physics which may lead to a correlation between memory and macromolecular organization and emphasizes the importance of the study of satellite cells in the nervous system. In the last two sections dealing with biochemical molecular structure and quantum biochemistry, chapters are included on


The article is devoted to the questions connected with the process of creation and functioning of the branch student labour centre in Federal State Educational Institution of Secondary Professional Education "Barnaul Trade Economic College". The author points out the main directions in the branch student labour centre activities.


The conclusion recaps Marcus's main points and findings: Reconstruction was the prime push factor; agricultural opportunities, existing networks, and Brazilian government inducements were primary pull factors; Confederado contributions to Brazilian life included agricultural and educational innovations and institutions; settlements in São Paulo generally prospered, while others failed; today's descendants have successfully integrated with the surrounding society. The book's contributions are manifold, especially the mapping of kinship and commercial networks, and the triscalar presentation— local/regional, national, and international.