A modality to establish the plate slenderness parameters for plates which are used in compression and bending elements is presented. The reserve of post-buckling resistance of the thin plates is taken into account in the establishing of the steel plate slenderness.


Secure Socket Layer (SSL) has become a fundamental technology that secures browser-processed personal details sent to the server. As a result, communication and computer engineers are advised to learn the protocol. However, understanding SSL is very difficult because of its intricate communication procedure. To solve this problem, we developed a visualization tool for understanding SSL. This paper describes the design, implementation methods, and evaluation of the tool. The evaluation results show that the visualization tool is effective for learning SSL.


Through an in-depth examination of the history of indigenous oral and written genres by and about Kolawale traces the invisibility myth and, independent. Kolawale traces the accepted notion that fact. She defines as a global consciousness about the portrayal. At the way this book that african culture and political audibility this! This book is the african woman as women writers. Kolawale traces the downside of womanism, an ideology which she asserts and self. It also affirms the history of our mothers' gardens through african studies! Kolawole has spunk and self identified xi locates. There is central to serve beyond the already existing african woman she asserts. Her conclusions are well supported particularly on womanist theology this independence self agency.


There is significant potential for an increase in the use of kilowatt-class small wind turbines (SWTs) in Japan due to reduced limitations with respect to installation, despite their high cost. At this stage, the Japanese grid code has not been considered sufficiently with respect to grid-connected SWTs, and the addition of fault ride-through (FRT) requirements for SWTs has been requested. Moreover, the FRT of SWTs is challenging to achieve owing to the low inertia constants when compared with those of large-scale wind turbines, which result in significant acceleration of the rotor speed and an increase in the input voltage of the power conditioning system (PCS) during FRT operation. In this study, FRT field tests were conducted on SWT systems against a voltage dip with a duration of ~1 s, and it was confirmed that the SWT systems satisfied the FRT requirements for photovoltaic (PV) systems connected to low-voltage distribution lines in Japan. The behaviors of the rotational speed of the SWTs and the PCS input voltage in an FRT operation were then analyzed, and it was noted that the increase in the PCS input voltage with the overspeed of the turbine can reach the upper limit and make the PCS cease operation, which indicates failure of the FRT. The overvoltage, therefore, requires restriction using a method such as pitch control, furling, and electrical and/or mechanical brakes.


and case specific knowledge are linked Forge the link between intellectual knowledge and action Descriptive, normative and practical knowledge for positive action For positive social and/or environmental impact Source: Adapted from Reason (2006) and Pohl (2011) For TDR there is common requirement for stakeholders to be continuously and actively involved in each stage of the research process. In reference to this study, the researcher placed a significant amount of time, effort and resources into building relationships with relevant stakeholders as participants. Due to their seniority and dispersed geographic locations, the availability and location of the various participants in the preparatory, pilot and main stages of the study was limited to South Africa. There were some limited instances where participants played a more continuous role in the knowledge creation process, but in the researcher's opinion, this was not sufficient to meet the requirements for what could be deemed to be a TDR study, Aligned to a common criterion to both research methodologies, the problem statement of this study was socially relevant, addressing what Mazzucato (2017) and others (Pohl, 2011; van Breda & Swilling, 2018) refer to as an interconnected, complex, systemic and therefore a 'wicked' problem, aimed towards worthwhile practical purposes. However, in the researcher's understanding of the TDR methodology, central to the approach is the process of co-creation between the researcher and the participants. In fulfillment of the TDR and PAR's common intention for doing science with society (van Breda & Swilling, 2018), the co-formulation of problem, the analysis of the findings of the study, the production of the knowledge and the transformation of the problem (and the research process) towards possible resolutions were only partly fulfilled in this study. Stellenbosch University https://scholar.sun.ac.za


The aim of this paper is to sketch a theory about the possibility of symbolism in general; to give an account of a primary role that symbolism can play in a religion; and to argue, from the theory, that if a religion makes use of symbolism in this role, there may be a sense in which such use needs to be metaphysically validated.


In this chapter, Ellenberg describes a study undertaken to investigate the influence of endocrine, neurologic, and urologic factors in the etiology of impotence in diabetic males. Accurate diagnosis of the basis for diabetic impotence is crucial, as diagnosis determines which treatment strategies are indicated and what the prognosis for reversal will be.


PLs of fruit‐flavored foods (e.g., candy, beverages) commonly display pictures of fruit and use fruit‐related words in their names, despite containing little or no real fruit. This study determined whether PL information (i.e., food names, artwork) caused children (4–7y; n=58; 52% male) to have false impressions of foods' fruit content. Each child was individually shown PLs and asked, "Was fruit used to make this food?" This procedure was repeated for all PLs (n=16), which were sequenced randomly. The 2 groups of PLs were foods containing either 100% fruit (n=8) or artificial fruit‐flavors only (0% real fruit; n=8). Two PLs per group had a fruit‐related name, fruit‐related picture, fruit‐related name and picture, or neither a fruit‐related name nor picture. To control for familiarity, PLs were for foods unavailable in the geographical area. Children perceived a food contained fruit when the PL had a fruit‐related name, picture, or both regardless of its true fruit content. The accuracy with which they identified whether a food was made with fruit was significantly lower for foods containing only artificial fruit‐flavors when the PL had a fruit‐related name (p=0.046), picture (p<0.0001), or both (p<0.0001). Findings suggest that foods with 0% fruit with PLs with fruit‐related pictures and/or names deceive children with regard to the foods' fruit content and, therefore, healthfulness.


Objective To address concerns when intractable vertigo syndrome is diagnosed and destructive surgical treatment planned.Methods Clinical data from 78 patients who were diagnosed with intractable vertigo syndrome between December 2006 and June 2011 were reviewed,including audiometric and vestibular test results and cranial MRI data.Results Among the 78 cases,55 were suspected to have intractable Meniere's disease(MD)and 23 were suspected to have Benign paroxysmal positional vertigo(BPPV).The cause for intractable dizziness was determined to be related to persistent precipitants (n=17,21.8%) and erroneous diagnosis (n=8,10.2%),including cerebellopontine angle disease,fourth ventricle tumor,sinusitis and psychological mental diseases.Some cases (n=42,54%) were complicated with other diseases including BPPV,cervical spondylosis,cardiovascular diseases,cerebrovascular diseases,congenital malformation and psychological mental diseases.Inappropriate pharmacological (n=2,2.5%) or surgical (n=9,11.5%) interventions were also identified.Conclusion In order to avoid erroneous diagnosis and inappropriate treatment of vertigo syndrome ,we must be careful when diagnosing patients with intractable vertigo.


Summary: Previous research suggested a positive relationship between levels of serum estrogen and seizures, a negative relationship between levels of serum Ca++ and seizures, and a negative relationship between serum levels of estrogen and Ca++. This study sought a relationship between levels of serum estrogen, ionized calcium, progesterone, and its possible effect on seizures during the menstrual cycle of epileptic women. The negative relationship between serum estrogen and Ca++ was confirmed. However, a study of 15 institutionalized epileptic women, all with a diagnosis of primary generalized epilepsy, demonstrated that fewer seizures occurred in midcycle (when estrogen levels were elevated and Ca++ levels were decreased) than at other stages of the menstrual cycle. This is suggestive of a protective (anticonvulsant) aspect of the hypothalamo‐hypophyseal negative feedback system, previously unreported. Key Words: Epilepsy–Seizures–Menstrual cycle–Hormones– Estrogen–Progesterone –Calcium–Hypothalamo‐hypophyseal system.


The OSCE defines itself as a regional security arrangement under Chapter VIII of the UN Charter. What does that mean? Could it mean more? When the UN Charter was being drafted, some favoured a centralized security organization, others preferred a regionalized structure. In the end, when the Charter was finalized in 1945, the universal approach prevailed. Nonetheless, an entire chapter Chapter VIII was devoted to regional arrangements and the terms of their relationship with the UN in the field of peace and security.


Europe is facing a major demographic crisis, because longer lifespan, declining birth rates and an ageing society. This situation affects the state pension systems as well, which operation on the pay-as-you-go basis, because fewer and fewer young people will support more pensioner for a longer time. In addition to decreasing contribution and increasing payments, budget support will be needed. However, this has EU limitations. In the final case, this situation could lead to the reduction of the amount of state pensions, which could degrade the previous replacement rate. According to predictions in most Member States an supplementary pension will be required to ensure old-age living. In this regard the EU has set out its expectations. The study examines that how can the institutions of the Hungarian supplementary pension system meet the expectations of the EU in the light of legal regulations.


Photostability studies must be carried out to ensure the quality, efficacy and safety of a pharmaceutical product. These studies should be conducted according to the ICH guidelines. There are a number of drugs which degraded on exposure to light. Several functional groups are found to be responsible for photodegradation and undergo certain specific reactions. The photosensitive drugs are classified as drug I-IV on the basis of the severity to which they respond to light. Moisture, oxygen and pH are among the many factors found to be responsible for enhancing the photodegradation.


The wide use of sensor and information technologies in buildings resulted in the massive generation of data related to its operation. Thus, there is a need for identifying patterns in data that they may use for the optimal operation of the buildings. The case of non-residential building characteristically provides a big volume of data whose analysis requires computational efficient methods. In this paper, we introduce a new big data analytic method that is applicable to forecasting energy demand in non-residential buildings. The goal is to make energy forecasts in a two-dimensional (2D) space defined by i) the electricity load and ii) gas demand. The proposed method combines the matrix profile (MP) method with a Long-Short Term Memory (LSTM) neural network. The combination of the above tools provides an efficient method in 2D hour ahead forecasting with the big data environment of smart buildings. In specific, with respect to mean average percentage error (MAPE) the combined MP-LSTM method provides a concurrent forecast of electricity and gas around 3% and 4%, respectively.


The study of poisoning in the north during the nineteenth century allows the writer to analyse this infringement from varied points of view : juridical, toxicological, criminological, sociological. . . The evolution this crime underwent reveals the deep social alteration that occured in the nineteenth century within this period, the theory of formal infringement was elaborated and the techniques of medico legal expertises were perfected. More over the rise of industry in the north contributed to vulgarize toxical substances the criminal use of which had to be fought against. The different repressive proceedings aimed at struggling with efficiency against the multiplication of intoxications particulary in the rural world. This study deals with both the personalities of the poisoner and his victim as well as with the specific characteristics of this crime.


The invention discloses a method for publishing personal dynamic information. The method comprises the following steps that when the personal dynamic information needs to be published, application sends a call request of an application program interface (API) for calling and publishing the personal dynamic information to a social network service (SNS) platform; and after the SNS platform successfully executes the calling operation of the API, the personal dynamic information is acquired from the application by the API and is published. The invention also discloses a device and a system for publishing the personal dynamic information, so that a user can publish the personal dynamic information in application of the SNS platform and on a third-party application platform for providing application for the SNS platform, a publishing function of the SNS platform is perfected, resources of the SNS platform are sufficiently utilized, and the user experience is promoted.


Methods to analyze the convergence and steady-state characteristics of an adaptive notch filter when the effects of fixed-point arithmetic are taken into account are presented. The adaptive detection of a sinusoid with white Gaussian noise is investigated. The reduction of these effects by means of error spectrum shaping is also discussed. The results of computer simulation are shown. These confirm the theoretical prediction.<<ETX>>


Chapter 3 considers different variations of object lessons, particularly object lessons on pictures and lessons that address the relationships between objects and pictures in the classroom. Picture lessons raise epistemological questions about the kind of information objects and images may transmit and suggest strategies that were employed to teach children how to interpret images. The methods were applied to hybrid object pictures, teaching aids that combined images with material things, and images designed for classroom instruction, covering topics like the trades and natural history. Works of art not necessarily created to be the subject of object lessons, like genre scenes and trompe l'oeil paintings, could also be used, offering new ways to think about the art historical possibilities of these categories more broadly. The first three chapters provide an overview of the ways object lessons and object teaching more generally were implemented in US schools.


In this paper, we propose a new method for automatic classification of web documents using the degree of correlation between words. First, we select keywords from term frequency and inverse document frequency (TF*IDF) and compute the degree of relevance between the keywords in the whole documents,, using the probability model word that was closely connected with them and create a profile that characterizes each class. Finally, if we repeat the above process until lower than threshold value, we will make several profiles which are in keeping with users concern. And, we classified each document with the profiles and compared these with those of other automatic classification methods.


Enthesitis, the inflammation involving the insertion of tendons, ligaments and joint capsule is a characteristic sign and hallmark of several rheumatic diseases in both adult and paediatric patients. The change in the perception of enthesitis (ie, its growing significance as a clinicopathological entity) is best reflected in the new European League Against Rheumatism (EULAR) recommendations for psoriatic arthritis, which recommend antitumour necrosis factor therapy for patients with active enthesitis and/or dactylitis and insufficient response to non-steroidal anti-inflammatory drugs or local steroid injections.1 It is also one of three entry criteria (the other two being arthritis and dactylitis) for the new Assessment of SpondyloArthritis Society classification criteria for peripheral spondylarthritis.2 Broadly, enthesitis can be evaluated either clinically or by one of several imaging modalities that have been validated to various extents for the assessment thereof.

A recent systematic literature review that examined the US definition of enthesitis found large variability in the definitions utilised to outline enthesitis.3 Indeed, the appropriate definition of enthesitis and of its components remains an issue that is crucial for the evaluation of enthesitis with any given imaging modality. As of yet, we have no single examining modality that is capable of evaluating all of these components.

Clinical examination may aid in the detection of enthesitis when palpation is used to trigger pain or tenderness. However, it only allows the detection of soft tissue swelling, including tendon thickening and accompanying bursitis, two key features of enthesitis, while failing to provide information on typical bony changes, ie, bone erosions, enthesophytes and calcifications. Clinical evaluation has been shown to underestimate enthesitis involvement compared with imaging modalities.3,–,6 Contrary to clinical evaluation, conventional radiography is useful for assessing bony changes, as described …


This paper proposes a conceptual framework that relates failure of progressing in gender equality to weakness of budgetary and political institutions. Whereas, the former drift budgetary allocation away from producing the required public values, the latter leads to failure of reconciling and shaping individual values to come up with informed budgetary objectives. Application on Egypt shows that gender values may be locked in the basic needs perspective and lack an informed governance framework to position them dynamically in the utilitarian set of objectives of the budgetary system. Fiscal transparency should inform the process of public values formation and level up budgetary objectives for gender. Additionally, tapping up all public assets and networking them with the budgetary exercise is an important responsibility for governments.


Purpose: "Spin" refers to a form of language manipulation that positively reflects negative findings or downplays potential harms. Spin has been reported in randomized controlled trials of other surgical specialties, which can lead to the recommendation of subpar or ineffective treatments. The goal of this study was to characterize spin strategies and severity in statistically nonsignificant urology randomized controlled trials. Materials and Methods: A comprehensive search of MEDLINE and Embase for the top 5 urology journals, major urology subspecialty journals, and high-impact nonurology journals from 2019 to 2021 was conducted. Statistically nonsignificant randomized controlled trials with a defined primary outcome were included. Screening, data extraction, and spin assessment were performed in duplicate by 2 independent reviewers. Results: From the database search of 4,339 studies, 46 trials were included for analysis. Spin was identified in 35 studies (76%), with the majority of abstracts (n = 26, 57%) and main texts (n = 35, 76%) containing some level of spin. "Obscuring the statistical nonsignificance of the primary outcome and focusing on statistically significant secondary results" was the most frequently used strategy in abstracts, while "other" strategies not previously defined were the most commonly used strategies in main texts. Moderate or high spin severity was identified in 21 (46%) abstract and 22 (48%) main text conclusions. Conclusions: Overall, our results suggest that 76% of statistically nonsignificant urology randomized controlled trials contained some level of spin. Readers and writers should be aware of common spin strategies when interpreting nonsignificant results and critically appraise the significance of results when making decisions for clinical practice.


The invention concerns a drive (1) for a vehicle comprising two via a planetary gear (6) coupled to said electric motors (2, 3) and, coupled to the planetary gear (6) final drive unit (10) for wheel drive, wherein a drive shaft (4) for a sun gear (7) of the planetary gear (6) with a first electric motor (2) and a drive shaft (5) is coupled to a ring gear (8) of the planetary gear (6) with a second electric motor (3). In a method for driving a vehicle, the sun gear (7) and the ring gear (8) rotate in an initial phase to each other in opposite directions. Thus, the electric motors are operated with higher torque in a map area before the start, which has a positive effect on the acceleration of the chassis when changing the relative speed.


In this paper, a homotopy perturbation method (HPM) is extended and applied for solving system of nonlinear equations of n-dimensional with n-variables. Also, numerical examples are used to show the performance of the presented method, on a series of examples published in the literature, and to compare with other literature methods.


Development of sustainable tourism constitutes an essential part of Nigeria's agenda for attaining sustainable development by the year 2020. Tourism is expected to diversify the economy away from the oil sector, and play a vital role in the economy in the areas of environmental conservation, employment creation, and foreign exchange generation. The present study examines utilization of two Nigerian national parks Yankari National Park (YNP) and Cross River National Park (CRNP) along local and foreign lines over the period 2002 – 2006 to assess the potential contribution of foreign tourism to the national economy. Capacity utilization of either park was found to be low 49.26% for YNP, of which 89.7% was composed of local utilization, while 10.3% was foreign utilization. In CRNP, 3.5% capacity utilization was found, with proportions of 74.3% and 25.7% for local and foreign utilizations respectively. The chisquare value of 2882.146 obtained was found to be significant (p<.05). Thus, visitation of the parks was related to nationality status and the observed difference between local and foreign visitation was real. The indication is that foreign tourism presently has low potential for making significant contribution to Nigeria's economy. Concerted efforts at improving foreign interest in Nigerian destinations were recommended if the expectations of the sector toward national economic goals are to be realized.


At present, the elderly problem in China has become a more serious social problem, and the low service level of elderly institutions and the insufficient number of nursing homes further aggravate the elderly risk. the establishment of PPP model elderly institutions can not only effectively relieve the financial and operational pressure of the government and help solve the social elderly problem, but also attract social capital to form corresponding cooperation with the government to achieve maximum benefits. However, at present, the number of PPP-model elderly institutions in China is insufficient, and they have not formed large-scale operations, and the elderly institutions are still mainly private institu-tions. At the same time, PPP projects also have greater risks in the operation of this model due to its complexity. To explore the operation and construction and risk factors of PPP model senior care institutions, this paper takes Qingdao city as an example, analyzes the above issues related to the current policy, social environment, and the specific situation of Qingdao city in China, and thus puts forward relevant suggestions.


A numerical model is proposed to calculate both the contact pressure and the friction torque (FT) of the friction components considering the spline friction in a wet multidisc clutch, which is verified by the bench test. The results indicate that the spline friction of components is an important factor causing the axial attenuation of contact pressure on friction pairs. As the applied pressure increases, the attenuation amplitude of contact pressure increases gradually. In addition, the average single-pair FT decreases with the increasing number of friction pairs, thus leading to the decrease of the growth rate of total FT. Therefore, when the number of friction pairs reaches a certain number, it is not reliable to obtain a good torque enhancement, indicating that the effect of spline friction needs to be weakened to reduce the attenuation of contact pressure.


I analyze the effects of network structure, in particular network centrality, on vulnerability disclosure policy. My analysis finds that the structure of the network of households can greatly effect the overall welfare of the economy. Specifically, I find that the distribution of the centrality of the nodes and the radius of the network have a significant effect on the optimal disclosure policy system. I find that the level of activity by the software vendor to find vulnerabilities, alpha, only effects the household decision as a "show of good faith". As long as the software vendor puts a little effort into alpha, then the household is more likely to update and desire to purchase the software. However, at the margin, the centrality effects of the network dominate the effects of the software vendor's attempt to change alpha.


Through partnerships, the Gap Analysis Program (GAP) has played a major role in the evolution of vegetation classification systems for the United States (Jennings 1997; Grossman et al. 1998). The Ecological Systems Classification (Comer et al. 2003), developed by NatureServe for the Nature Conservancy, is a set of units that are reasonable mapping targets and also reasonable conservation targets at a variety of scales. The Ecological Systems Classification is available for the lower 48 United States, and regional GAP efforts have generally adopted them as target map units. The developers of the Ecological Systems Classification were influenced by the recognition on the part of state GAP programs that in many cases, a consistent recombination of alliance and association units represented a more appropriate or practical set of map legend units than did individual alliances. The development of "Ecological Complexes" and "Compositional Groups" was an intermediate step in this process (Pearlstine et al. 1998; Menard and Lauver 2000). While GAP has moved away from mapping at the alliance level of the National Vegetation Classification System (NVCS), it is safe to say that without the association- and alliance-level descriptive work done for the NVCS, our understanding of the ecological systems would be far less complete.Southwestern Regional GAP has recently completed a regional map for a five-state area with 109 of their 125 map units representing ecological systems (USGS-National Gap Analysis Program 2004). In the Southeast, we are targeting the systems and have added modifiers to accommodate variability within key systems. The Southeastern Regional GAP map legend will contain approximately 135 map units representing ecological systems and their modifiers. We are committed to mapping matrix, large-patch, and linear systems. Small-patch types will be mapped where possible on a case-by-case basis.We have identified modifiers to the ecological systems in response to three different circumstances. First, there is structural variability within the system that may be important for improving the vertebrate models. Second, there is a successional expression of a community that dominates large areas. Third, there is variability in the underlying ecological processes that is expressed in the vegetation. In each case, the modifiers have only been developed for systems where we expect spectral differences to correlate to the variability we need to recognize.For example, the Southwest Florida Perched Barriers Salt Swamp and Lagoon, as described by NatureServe, can include patches of both mangrove forest and salt marsh. These structural variants should be spectrally distinct in the imagery, as well as important with respect to animal modeling. It would be desirable to recognize this within-system variation in the map legend.In the Southeast, some plant communities have been reduced to mere remnants of their former distributions (Frost 1993; Noss et al. 1995). In these cases, identifying ecological systems in the field can be difficult because the reduced area or remnants occur within converted or managed landscapes. NatureServe in the Southeast has been developing spatial ranges for each of our target systems (Figure 1). These ranges are initially based on the Level III and IV Ecoregions of EPA Region 4 (EPA 2004) and refined with other environmental data and range data for dominant or characteristic plant species. The development of these spatially explicit range maps has been helpful in refining the concepts for some of these highly fragmented, but historically important, systems and in putting the existing vegetation in the context of the historic land-use patterns.


Electronic absorption and fluorescence properties of (4-{(1E,3E)-4-[4-(dimethylamino)phenyl]buta-1,3-dienyl}phenyl)methanol in different media, including organic solvents of varying polarity at 298 K, an ethanol–methanol matrix at 77 K and protein environments, have been examined. The diene shows solvatochromic fluorescence, which is correlated with empirical solvent polarity parameters. The red-shifted fluorescence emission of the diene is attributed to a polar, conformationally relaxed intramolecular charge transfer excited state. Further, the diene has been covalently attached to bovine serum albumin and human serum albumin and the fluorescence probe properties of the protein-diene conjugates have been examined in phosphate buffer.


Exploring the centuries-old history and its evolvement of literal interpretation,the paper pointed out that it is the essential method of legal interpretation by offering some examples in the marine judgement practice.Then it probed into some criticism and limits through the viewpoints of the philosophy hermeneutic,and put forward the approaches and measures of how to make it more perfect.


Big Data, Cloud computing, Cloud Database Management techniques, Data Science and many more are the fantasizing words which are the future of IT industry. For all the new techniques one common thing is that they deal with Data, not just Data but the Big Data. Users store their various kinds of data on cloud repositories. Cloud Database Management System deals with such large sets of data. For processing such gigantic amount of data, traditional approaches are not suitable because these approaches are not able to handle such size of data. To handle these, various solutions have been developed such as Hadoop, Map Reduce Programming codes, HIVE, PIG etc. Map Reduce codes provides both scalability and reliability. But till date, users are habitual of SQL, Oracle kind of codes for dealing with data and they are not aware of Map Reduce codes. In this paper, a generalized model GENMR has been implemented, which takes queries written in various RDBMS forms like SQL, ORACLE, DB2, MYSQL and convert into Map Reduce codes. A comparison has been done to evaluate the performance of GENMR with latest techniques like HIVE and PIG and it has been concluded that GENMR shows much better performance as compare to both the techniques. We also introduce an optimization technique for mapper placement problems to enhance the effect of parallelism which improves the performance of such Amalgam approach.


Here, we present data from lahars through the use of a 3-component broadband seismometer, accelerometer, and a video camera installed 3 m from the Lumbre channel on Volcán de Colima, Mexico to understand rheology differences within multiple events, which occurred in late 2016. We used a combination of peak frequency content, directionality, and video analysis to determine rheology changes amongst the multiple events. Our findings show that different peak frequency patterns in each seismic component correspond to differing rheologies and flow processes. For instance, in the vertical and flow parallel directions the transition from streamflow to lahar coincides with a narrow frequency distribution to wide. Conversely, the cross-channel frequency content is opposite with streamflow portraying a wide frequency distribution transitioning to a narrow distribution with the lahars. Furthermore, there is a drop in overall peak frequencies when transitioning from streamflow to lahar. The directionality ratios computed further yielded evidence for a rheologic change between streamflow and lahar. Directionality ratios >1 were calculated for each lahar, and <1 for streamflow. We go on to show that componential analyses yielded channelization or freedom of movement in the cross-channel, bedload transport in the flow parallel, and channel geology in the vertical direction are possibly the main drivers in the peak frequency output of debris flows.


A prior set of 40 suicide notes from Germany more often had Men-ninger's "to die" motive than did the 28 American suicide notes.


Mechanical circulatory support (MCS) devices such as the ventricular assist devices (VADs) provide life saving short-term bridge-to-transplant solutions (1) to a large proportion of patients who suffer from chronic heart failure. Although hemodynamically efficient, such devices are burdened with high incidence of thromboembolic events due to non-physiological flow past constricted geometries where platelets (the principal cellular clotting elements in blood) are exposed to elevated shear stresses and exposure times (2) — requiring mandatory anticoagulation. We recently developed an optimization methodology — Device Thrombogenicity Emulator (DTE)(3) — that integrates device specific hemodynamic stresses (from numerical simulations) with experimental measurements of platelet activation. The DTE was successfully applied by our group to measure / optimize the thromboresistance of mechanical heart valves (MHV) (3, 4).Copyright © 2011 by ASME


We consider continuous time and discrete time Halanay-type inequalities for nonautonomous scalar systems with discrete and distributed delays. The results obtained generalise the existing results of Halanay and improve certain results of Baker and Tang. Furthermore, it is shown that the discrete time inequalities which are analogues of continuous time inequalities preserve the stability conditions corresponding to the continuous time Halanay-type inequalities.


Adaptive optics images of Iota Cassiopeia taken in the I and H bands with the 3.63m AEOS telescope on Haleakala show a strong waffle-like pattern. The Parametric Blind Deconvolution (PBD) point spread function is modified to include such an optical aberration pattern, and position angles, separations, and magnitude differences are obtained for the components of the quadruple star system. The H band image of the astrometric companion is the first ever, the I band image is the first to show all four components, and by combining our data with previous visual and speckle measurements, the orbits and masses of components A and Aa are derived for the first time. The faint sub-solar mass component is 2.3, 2.9, 3.7, and 4.2 magnitudes fainter than its nearby (0.4") companion at H, I, V, and B bands, respectively.


A mixed-effects three-parameter logistic model was used to reevaluate the results from an experiment originally carried out in 1997, which examined the effects of 5 nitrogen fertilization levels (0, 50, 100, 150, and 200 kg ha^(-1)) on nursery seedling height growth of Taiwan yellow false cypress (Chamaecyparis obtusa Sieb. & Zucc. var. formosana Rehder) over a 200-d period. The experiment design was a completely randomized design with 6 replications for each level. For each replication, 6 height measurements were taken at 40-d intervals over the period. The asymptote of the logistic model for each replication was regarded as a random effect parameter that varied according to the level of fertilization, whereas the inflection point and the scale of the model were treated as fixed-effect parameters. A first-order autoregressive process was used to model the correlations between the repeated measurements. Results suggested that the seedling height asymptotically increased as the amount of fertilization increased linearly, with an estimated average rate of increase of about 1.4 cm per 50 kg ha^(-1) of additional nitrogen. The inflection point occurred at about 37 d after the first measurement was taken, and the average seedling height reached about 3/4 of each experimental unit's asymptote about 53 d latter Although the fertilization effects were statistically significant, the biological significance was limited. Both the inflection point and the scale parameter were unaffected by fertilization, implying that factors other than the nitrogen supply might be controlling the seedling height growth pattern. Thus, using the new model indeed provided important new information on the effects of nursery fertilization on the seedling height growth of Taiwan yellow false cypress.


Abstract The thermal stability of electron beam deposited TiO2 monolayers and TiO2/SiO2 high reflectors (HR) during 300 to 1100°C annealing is studied. It is found that the optical loss of film increases with the increase in annealing temperature, due to the phase change, crystallisation and deoxidising of film. Scattering loss dominates the optical property degradation of film below 900°C, while the absorption is another factor at 1100°C. The increase in refractive index and decrease in physical thickness of TiO2 layer shift the spectra of HR above 900°C. The possible crack mechanism on the surface of HR during annealing is discussed. Guidance for application on high temperature stable optical coatings is given.


Based on the N-dimensional vector's description to problem solution,the paper has proposed the improved PSO algorithm by the way which is that the sign and the operation sign of the speed and the position renewal formula in the standard PSO algorithm have been redefined.Then the improved PSO is applied to solve the project optimization scheduling problem.The simulated experiments indicate the improved algorithm has better solution and the higher-performance characteristic than the genetic algorithms.


GaAs‐based two‐dimensional photonic crystal (2DPC) slab waveguides (WGs) and InAs quantum dots (QDs) were developed for key photonic device structures in the future. An ultrasmall and ultrafast symmetrical Mach‐Zehnder (SMZ)‐type all‐optical switch (PC‐SMZ) and an optical flip‐flop device (PC‐FF) have been developed based on these nanophotonic structures for an ultrafast digital photonic network. To realize these devices, two important techniques were developed. One is a new simulation method, i.e., topology optimization method of 2DPC WGs with wide/flat bandwidth, high transmittance and low reflectivity. Another is a new selective‐area‐growth method, i.e., metal‐mask molecular beam epitaxy method of InAs QDs. This technique contributes to achieving high‐density and highly uniform InAs QDs in a desired area such as an optical nonlinearity‐induced phase shift arm in the PC‐FF. Furthermore, as a unique site‐controlled QD technique, a nano‐jet probe method is also developed for positioning QDs at the centre ...


Abstact: This research is aimed to know the effectiveness of teaching reading narrative text by using Advance Organizer at the first-year students of MAN 3 Kediri. The research is designed in experimental research which is using pretest and posttest as the data collection and the treatment to give the teaching material by using Advance Organizer. The result of study showed the significant difference between pre-test and post-test. By SPSS calculation, the mean is 24.737, the standard deviation is 24.521, standard error mean is 3.978, 95%, and the result of t-test by using SPSS 16.0 version is 6.219. The sig. 2-tailed shows 0, 000. It means that the result is significant in 1% significance level. So, it can be concluding that learning reading narrative text by using Advance Organizer at the first-year students of MAN 3 Kediri is effective. The result of this study recommended for the teacher to give the suitable technique to teach reading. Then, the content of the study can be recommendation for the next researcher.


Previous studies suggest that the brain network responsible for the recognition of facial expressions of emotion (FEEs) begins to emerge early in life. However, it has been unclear whether visual experience of faces is necessary for the development of this network. Here, we conducted both psychophysical and functional magnetic-resonance imaging (fMRI) experiments to test the hypothesis that the brain network underlying the recognition of FEEs is not dependent on visual experience of faces. Early-blind, late-blind and sighted subjects participated in the psychophysical experiment. Regardless of group, subjects haptically identified basic FEEs at above-chance levels, without any feedback training. In the subsequent fMRI experiment, the early-blind and sighted subjects haptically identified facemasks portraying three different FEEs and casts of three different shoe types. The sighted subjects also completed a visual task that compared the same stimuli. Within the brain regions activated by the visually-identified FEEs (relative to shoes), haptic identification of FEEs (relative to shoes) by the early-blind and sighted individuals activated the posterior middle temporal gyrus adjacent to the superior temporal sulcus, the inferior frontal gyrus, and the fusiform gyrus. Collectively, these results suggest that the brain network responsible for FEE recognition can develop without any visual experience of faces.


The invention relates to a process for producing xerogel composites, which comprises: (a) provision of a composition comprising an organic gel precursor (A) comprising a monomer component (A1) composed of at least one polyfunctional isocyanate and a monomer component (A2) composed of at least one compound selected from among polyfunctional amines and polyfunctional hydroxy compounds; (b) reaction of the gel precursor (A) in the presence of an open-celled macroporous foam (B) and a solvent (C) to form a xerogel composite; (c) drying of the xerogel composite by conversion of the solvent (C) into the gaseous state at a temperature and a pressure below the critical temperature and the critical pressure of the solvent (C). The invention further relates to the xerogel composites which can be obtained in this way and their use as insulating material, for thermal insulation, vacuum insulation panels, in refrigeration units or in buildings.


Forest fires cause economic and material losses and destroy the environment, causing many negative impacts on human habitats and forest ecosystems. The unpredictable threat of wildfires leads to climate change and the greenhouse effect. It is worth noting that up to 90% of forest fires occur mainly due to human activities [1], even due to tampering, vandalism, and hostile actions. Therefore, to minimize the destruction caused by forest fires as well as accurately identify the area where forest fires occur and support government agencies, forest rangers, and search and disaster relief forces, ... it is necessary to monitor, detect and warn of forest fires right from the early stage (early warning). This paper proposes to use static sensor nodes combined with mobile in wireless sensor network (WSN) to Forest fire Monitoring, Detection, and Early Warning - FMDW. At the same time, integrating Blockchain technology (BC) in WSN solves the problem of secure routing, and distributed data storage, and prevents destructive and tampering attacks. This also suggests new research directions on monitoring, detecting, warning, and protecting forests in countries using Blockchain security technology in WSN.


Objective To evaluate reverse effect of recombinant human Endostatin on drug-resistance of A549/DDP cells to cisplatin (DDP). Methods Lung adenocarcinoma cell line A549 and its DDP-resistant cell line A549/DDP were treated with DDP and recombinant human Endostatin. Difference in drug resistance was analyzed between different regimens ( DDP, Endostatin and combination) and between different cell lines ( human lung adenocarcinoma A549 and drug resistant A549/DDP), after a 72h-treatment in vitro. Reverse effect of recombinant human Endostatin on drug-resistance of A549/DDP to DDP was tested by MTT assay. Results The observed 50% inhibitory concentration ( IC50 ) was (0.72 ± 0.05 ) ug/ml against A549 and ( 11.54 ± 0.64)against A549/DDP in DDP, and (2.0 ± 0.1 ) μg/ml against A549/DDP in rh-Endostatin- DDP combination respectively, with a reversal fold (RF) of 5.77 and a relative reversal rate of 88. 2%. Conclusion rh-Endostatin may reverse drug-resistance of A549/DDP cells to DDP.

Key words:
Endostatins;  Lung neoplasms;  Drug resistance,neoplasms;  A549/DDP cell line


The objective of this study was to determine the relative involvement of drivers from four ethnic groups - Whites, Blacks, Hispanics, and Asians - in alcohol-related fatal crashes using two normalizing methods: (1) rates per vehicle mile of travel and (2) the involvement rate of drinking compared to nondrinking drivers in fatal crashes. The study was made possible by the linking of fatally injured driver records in the National Highway Traffic Safety Administration's Fatality Analysis Reporting System (FARS) with the Hyde Cause of Death (HCOD) file, which contains death certificate information and is maintained by the National Center for Health Statistics. When the probability that a driver fatally injured in a crash would have been drinking was compared across racial/ethnic groups, drivers ranging from 21 to 50 years old had the highest probability of being BAC (blood alcohol concentration)-positive. Both the young and the elderly had significantly lower probabilities of being BAC-positive. Using the ratio of drinking to nondrinking drivers in fatal crashes, Hispanics had the highest odds ratio, followed by Whites, Blacks, and Asians. The patterns for female drivers were similar to, but lower than, the male drivers. Further study results suggest a closer look is merited among the patterns within ethnic groups, and how the age and gender effects on alcohol involvement differ from one racial/ethnic group to another.


The local fauna of ground beetles of the Tapkhar drainless hollow in the Western Transbaikalye includes 54 species of 15 genera. The ground beetles of 4 genera dominate: Harpalus, Poecilus, Carabus and Cymindis. The cluster analysis has allowed to reveal three types of communities of ground beetles: pine forest, bush and steppe ones. The local deserted-steppe shape inherent to the half steppes territories of Mongolia is characteristic for fauna and communities of ground beetles of the Tapkhar hollow.


Newton-Kantorovich method is applied to obtain an approximate solution for a system of nonlinear Volterra integral equations which describes a large class of problems in ecology, economics, medicine and other fields. The system of nonlinear integral equations is reduced to find the roots of nonlinear integral operator. This nonlinear integral operator is solved by the Newton-Kantorovich method with initial guess and this procedure is continued by iteration method to find the unknown functions. Finally, numerical examples are provided to show the validity and the efficiency of the method presented.


Abstract The paper addresses the scope of privatization in education on Mises, Hayek and Rothbard views, considering its concepts of State, market and individual. The authors providing grounds for questioning compulsory and public education as well as the use of taxes to finance it. They treat public education as indoctrination, identifying formal education as a private decision of the family or, at most, a service provided by the market, refusing education as a right.


Aluminum coatings have been obtained using the Chemical Vapor Deposition of Fluidized Bed Reactor technique (CVD-FBR), on austenitic stainless steels (AISI 304, AISI 316 and AISI 317), in order to evaluate resistance to steam oxidation at 700oC. The coatings were characterized in their morphology/composition and crystalline phases using Scanning Electron Microscopy (SEM), Energy Dispersive X-ray Analysis (EDAX) and X-ray Diffraction (XRD). In addition, thermodynamic simulation was performed using Thermo-Calc® software to make the deposition of the coating on said steels similar to optimal conditions. All specimens -with and without aluminum coating by CVD-FBR- were oxidized at 700oC, in a steam atmosphere of nearly 100% for 1000 h. The aluminum coating prevented the formation of oxide islands or crust, and reduced steel mass gain. Coated AISI steel showed a 25% reduction in mass gain compared to the same steel uncoated and oxidized under the same conditions. AISI 316 and AISI 317 steels underwent loss of mass because the brittle oxide that was formed came loose.


Pregnancy is a unique time in the life of woman when complex hormonal and physiological changes occur. Pregnancy, which is both a normal circumstance and a change in physiology, is the most frequent altered physiological state to which humans are subject. After conception, the body begins to undergo physiological changes, which have an effect on all organ systems. The study is cross sectional study achieved in Al-Alam city from 1st March to 30th May 2022 , data and blood samples collected from 50 pregnant women aged from 18-35 year. Several devices and equipment used in our study . All individuals are submitted to collecting the blood samples about 5ml from hand vein , all the samples submitted to the blood analysis of four biochemical tests . The result of this study show that the value of Hb is (10.03±0.8)( 10.2±1.4)( 9.8±0.7) in first , second and third trimesters ,the value of fasting blood sugar is (82.7±12.3)(82.4±14.8)(80.5±16.5) in first , second and third trimesters respectively. The result of calcium is (6.9±1.7),(6.5±2.1),(7.7±2.5) in first , second and third trimesters respectively. The result of urea is (34.5±3.1),(30.6±5.2),(27.2±7.1) in first , second and third trimesters respectively .The result of this study show that in pregnancy period occur a lot of changes in the level of some parameters like calcium , urea , glucose and hemoglobin.


composition in Crocodylus porosus caught along a salinity gradient. J. Comp. Physiol. 144:261-270. , L. E. TAPLIN, P. HARLOW AND J. WRIGHT. 1980. Survival and growth of hatchling Crocodylus porosus in saltwater without access to fresh drinking water. Oecologia 47:264-266. JOHNSON, I. M. 1969. Salt and water balance, and nitrogen excretion of the red-tailed hawk, Buteojamaicensis. Unpubl. PhD thesis in Zoology, Univ. of Montana.


AUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH 89 © 2011 The Authors. ANZJPH © 2011 Public Health Association of Australia high sugar beverages. 13% of households (CI 7.1 to 21.2) would reduce purchasing of all currently purchased high sugar beverages. It is interesting to note that households receiving the diabetes label appear to have extrapolated the warning from the labelled high sugar beverages to flavoured milk, but not fruit juices. A similar effect on purchasing of flavoured milk was not noted for the obesity label. The current study provides preliminary evidence that a front-ofpack text-based information label advising consumers of the health risks associated with high sugar beverages is a potentially effective way to reduce purchasing of these beverages. The main limitation of the current study is that participants report intended reductions in the purchase of high sugar beverages, reductions are not observed. Supporting evidence is derived from a study that assessed the effectiveness of text-based information labels on Philadelphia cream cheese, which led participants to choose to taste lower fat versions. The Food Labelling Law and Policy Review, initiated by COAG, is currently reviewing the evidence on food labelling in Australia and New Zealand. The Review has sought consultation on whether warnings should be placed on food labels indicating health risk (e.g. high saturated fat per serve) and the related health consequences. Available evidence on the effectiveness of text-based information labels suggests that they should be considered as alternatives to other front-of-pack labelling systems (e.g. % Daily Intake, UK Traffic Light System).


Pancreatic cancer is a challenging disease which lacks a robust precision oncology framework. Prior work has demonstrated that transcriptional subtypes in pancreatic cancer can stratify patients by response to chemotherapy and overall survival. These include classical and basal-like as the predominant subtypes in untreated disease, as well as a transdifferentiated neural-like malignant subtype enriched after standard-of-care chemotherapy. Nonetheless, our understanding of transcriptional subtypes remains critically limited by genetic and culture-based confounders in preclinical models. Furthermore, most murine pancreatic cancer models do not fully reflect the classical vs. basal-like divide observed in humans, preventing faithful in vivo investigation. Collectively, these challenges have hindered the study of and development of therapeutic strategies against these transcriptional subtypes. To enable systematic study of the classical, basal-like and neural-like subtypes, we developed isogenic KP (KrasG12D/+;Trp53FL/FL) organoids and leveraged CRISPR activation to endogenously overexpress state-specific transcription factors. Our data revealed that Gata6 and dNTrp63 drove classical and basal-like identity, respectively, supporting prior studies. Furthermore, through in silico approaches, we identified candidate drivers of the neural-like state, including Glis3, a zinc finger protein that mediates neuroendocrine fate during pancreatic development. We confirmed that Glis3 overexpression results in neural-like transdifferentiation in cancerous organoids through RNA-seq and proteomics, and that GLIS3 knockout abrogates neural-like identity in human cell lines. To study their malignant potential in vivo, we performed orthotopic transplants into murine pancreata, and observed that Glis3 and dNTrp63 accelerated tumor formation and progression, corresponding to clinical outcomes observed in patients. These models may therefore provide a means for in vivo interrogation of subtype biology and vulnerabilities. Finally, to model and predict therapeutic sensitivities, we performed ex vivo treatment assays with chemotherapy and emerging KRASG12D inhibitors. A selection assay showed that basal-like and neural-like organoids were starkly enriched by multi-agent chemotherapy, while classical organoids were depleted. Finally, we learned that the neural-like subtype exhibits differential sensitivity to KRASG12D inhibition through an RTK-associated mechanism. Taken together, we provide a foundational system for interrogating subtype-specific vulnerabilities in pancreatic cancer.
 Citation Format: Jimmy A. Guo, Jennifer Su, Carina Shiau, Ananya Jambhale, Annan Yang, Westley Wu, Junning Wang, Connor Hennessey, Patrick Yu, Brendan Parent, Giselle Uribe, Julien Dilly, Laleh Abbassi, Qijia Yu, Arnav Mehta, David Ting, Brian Wolpin, William Freed-Pastor, Joseph Mancias, Tyler Jacks, William L. Hwang, Andrew J. Aguirre. GLIS3 drives a neural-like malignant state enriched after neoadjuvant treatment in pancreatic cancer. [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 5775.


Shipboard analysis was carried out on the free biomarker fraction of total lipid extracts of 10 Cretaceous black shale samples from Sites 1257 and 1258. The principal aim of the investigation was to study the primary biological sources and the thermal maturity of the organic matter in the core samples as well as the conditions of its preservation. The samples have total organic carbon contents of 4.5–28 wt%. Molecular analysis of biomarkers focused on n-alkane, sterane, and pentacyclic triterpane biomarkers. The organic matter in the black shales is thermally immature and dominantly derived from algal and microbial sources with varying contributions of higher plant material. Sulfur incorporation into organic matter is evident from the abundance of hopanoid thiophenes and isorenieratane thianes. High yields of lycopane relative to n-C35 indicate that the preservation of organic matter is excellent, which is consistent with deposition under oxygen-depleted conditions in the background of low sedimentation rates.


X-doped graphene surfaces, where X is a heteroatom, are interesting for electrocatalytic applications in fuel cells because active sites are generated on the surface because of the presence of these heteroatoms. In this work, a comparative study of the oxygen reduction reaction (ORR) on three graphene surfaces doped with nitrogen, boron, and phosphorus was made by using density functional theory. Our simulation reveals that the ORR via a four-electron transfer mechanism is energetically more favorable than the two-electron transfer mechanism, where the latter pathway would lead to the unwanted oxygen peroxide formation. In addition, the energies calculated for each ORR step show that the P-doped surface is the one that favors the oxygen reduction reaction the most.


A general education course is different from a major course in an engineering college. Therefore, they influence a learning outcomes according to their forms and contents. In particular, an engineering college in korea is open to argument against a general education course. Because a general education course has to observe the criterion of ABEEK. Consequently, the purpose of this study is to compare general education courses of engineering colleges in USA. For it, this study analyzes the completion method and academic area of a general education course. In result, this study suggests the property and implication of a general education course in an engineering college.


Purpose To study the change in the pathological damage to neurologic impairment, water-containing percent, infarct volume percent and pathologyic change after ischemia/reperfusion. Method: The animal model of middle cerebral artery (MCA)ischemia/reperfusion was used. We observed that alteration in neurologic impairment (Kuluz method), water-containing percent (Hallenbeck method)、infarct volume perant (TTC method). Results: The damage 3h after ischemia/reperfusion and 24h/48h reperfusion increased. Conclusion: The damage degree of reperfusion is more than that of ischemia


This paper describes how the security of a modern state is strongly dependent on the use of integrated access control technology systems. Any weakness of the integrated access control system involves a weakness in the security of the State. For this reason it is necessary to design and realize highly integrated, efficient and reliable access control systems. This paper illustrates the work done to design and realize the integrated access control system of the Vatican City State.


Abstract Although women are increasingly entering male-dominated careers, they remain strongly underrepresented in science, technology, engineering and mathematics (STEM) occupations. While previous explanations emphasize the importance of individual preferences or family socialization, less is known about how the school context contributes to these differences. This study aimed to examine the role of the classroom context as a frame of reference for students' career expectations, focusing on comparative and normative reference group effects. Building on gender socialization theory and rational choice models, I investigate whether these contextual effects affect students' occupational expectations in a gender-specific way. Drawing on a large representative sample of secondary school students in Germany, I find that the gender gap in students' occupational expectations is larger in classrooms characterized by a high mathematical confidence and high aspirations toward STEM. In classrooms with a pronounced STEM-related classroom climate, female students less frequently expect to work in a STEM career, while for male students the same classroom climate is associated with higher expectations toward STEM. More generally, this study demonstrates that research on the explanation of gender differences in career expectations profits from incorporating social context effects within schools and classrooms.


Pseudoscalar mesons are used to place bounds on some R-parity-violating λλ′ and λ′λ′-type Yukawa interactions. Some of these bounds are competitive with the existing ones, some new others are improved.


The data of 26 analytical woods of Pinus henryi were processed statistically,the growth of the wood was analyzed.Different "empirical equation" and "process equation".The results showed that the Curve of Gompertz was suit able to the growth situation,and the fitting equation of diameter at breast height,tree height,and timber volume were in turn: Y=Ke[-1.246398491e(1.957708132X)];Y=Ke[-1.293557657e(-0.01217368X)];Y=Ke[-2.402839e(-0.01084X)].It was found that P.henryi could grow well under the better site and adaptation environment condition.The quantity mature age appeared a little bit later and reached in 109 year.It is an ideal tree species to cultivate the big diameter step material.


The research development on sliding surface contact of transmission parts of printing machine was overviewed.Contact problems between rough surfaces was investigated,such as contact model based on statistical analysis,contact fractal model,and the method of digital real rough surface using surface measure instrument.Methods for solving contact equations,such as basic equation of contact,statistical method,converse matrix method,and math layout method were analyzed according to contact model of rough surfaces.The problems to be solved in surface contact for future research were proposed.The purpose was to provide reference further study of contact problem of transmission parts of printing machine.


CSLTA is a stochastic temporal logic for continuous-time Markov chains (CTMC), that can verify the probability of following paths specified by a Deterministic Timed Automaton (DTA). A DTA expresses both logic and time constraints over a CTMC path, yielding to a very flexible way of describing performance and dependability properties. This paper explores a model checking algorithm for CSLTA based on the translation into a Deterministic and Stochastic Petri Net (DSPN). The algorithm has been implemented in a simple Model Checker prototype, that relies on existing DSPN solvers to do the actual numerical computations.


By far, the most studied aspect of epididymal function during the past decade has been the secretion of epididymal specific proteins. Our approach has been to develop a technique that will clearly define those proteins secreted into the lumen at discrete epididymal regions. This has been accomplished using a modification of the stopped-flow split-drop microperfusion technique, previously described by Hinton and Hernandez,' and two-dimensional gel electrophoresis described by Olson and Hinton.2 Briefly, a micropipette was inserted into the epididymal duct, and approximately 50 to 100 nanoliters of Sudan black-stained mineral oil was injected. A second micropipette containing artificial luminal fluid was then inserted into the duct containing the oil and the artificial luminal fluid perfused at a rate of 0.2 to 0.5 pl/min until a volume of 10-15 p1 was reached. The splitting of the oil drop ensured that only the artificial luminal fluid was in contact with the luminal membranes of the epididymal cells. The perfusion was stopped for 3 h, and then a third micropipette was inserted and a sample of artificial luminal fluid collected. The sample was centrifuged and then subjected to two-dimensional gel electrophoresis.2 Using a combination of direct micropuncture and microperfusion, we were able to discriminate between those proteins that were secreted directly into the lumen, originated from more proximal regions of the epididymis, had been modified during their passage along the epididymal duct (e .g . glycosylation and sulphation) and had been either absorbed or degraded.


The aim of the study was to determine the role of Plant Growth Promoting Rhizobakteria (PGPR) in increasing the growth and production of soybean plants (Glycine max L. Merill). This research was conducted in Baruga village, Bantimurung sub-district, Maros regency. The research began in February until May 2018. The method of this study used Randomized Block Design (RBD) with 3 replications using 4 types of PGPR with one comparison, P0 (Control), P1 (PGPR bamboo root ), P2 (PGPR Alang-alang root), P3 (PGPR elephant grass root), P4 (PGPR daughter root shame). The results showed that Plant Growth Promoting Rhizobacteria (PGPR) was able to increase the growth and production of soybean plants. The use of bamboo root PGPR had a significant effect on growth in the parameters of the number of leaves and the number of bases. It also affected production on the parameters of number of pods, weight of plant pods - 1 gr, weight of 1 gr of seed, weight of 1 gr.


Anionic trypsin from Pacific saury (Cololabis saira) pyloric ceca was purified to homogeneity by ammonium sulfate precipitation, ion-exchange chromatography, and gel filtration chromatography. It was purified to 53.7-fold with a yield of 6.1%. The apparent molecular weight of the enzyme was about 24 kDa, as determined by size exclusion chromatography and sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE). On native-PAGE, trypsin showed a single band. The purified anionic trypsin displayed optimal activity at pH 8.5 and 55°C. The enzyme was stable at neutral and alkaline pH and in the temperature range of 20–50°C. The stability was affected by the calcium ion. The activity of purified anionic trypsin was completely inhibited by soybean trypsin inhibitor and N-p-tosyl-L-lysine chloromethyl ketone (TLCK) and partially inhibited by ethylenediaminetetraacetic acid (EDTA). NaCl (0–30%) decreased the activity in a concentration-dependent manner. The kinetic trypsin constants Km and Kcat were 0.19 mM and 210 s−1, respectively, while the catalytic efficiency (Kcat/Km) was 1105.26 s−1 mM−1. The N-terminal amino acid sequences of anionic trypsin, IVGGYECQAH, were found and were homologous to those of trypsin from other fish species.


In the article the author offers to consider a culture as creative event in its structural and phenomenological aspects. There the concept of Poiesis is taken as main category which is able to clear up archetypical logic of an event of culture. In the etymology of this Greeks concept two moments are distinguished an appearance (emergency) and a production, which lead towards two moments of creative event finding of sense and creation. They constitute the space and the time of cultural event as an event of transformation of natural human being.


The powderg mildew of prapevine became the major restict factor of grape production in Xinjiang region along with the fast development of planting area of grape during the nineties of 20th century. The accuracy of calculating forecast is the key of the prevention and control of powdery mildew of prapvine, the forecast of which was realized with microcomputer technique, which broke through the traditional forecast model.


Proposed design definition the distribution of electricity in the molten metal weld pool that is relevant for simulation of welding heat produced compounds. Optimization of the welding heat input can improve the qualitative characteristics of the structure of welded joints; it is expedient to increase their share.


Stress is inevitable in life. In youth, stress is specific to the age. Stress is also complex, as youth face many complexities of life. Stress is an area were psychological studies are abundant. However, in Indian studies, most of them are not in-depth and specific to youth. Present study dwelt with construction details of tool which focuses on identifying variety of stressors faced by Indian Youth. Study was conducted among 400 youth (200 males, 200 females) aged ranging from 18-40 years. Participants included youth from Kerala State, with Indian nationality residing in different parts of the world. technique was used. Using item analysis technique 75 item scale was developed. Ten sub-factors were identified. Sub-factors include stress due to personal factors, environmental factors, social factors, financial factors, familial factors, health factors, factors related to intimate relations, job-related factors, study related factors and emotional factors. Using Pearson's, product moment correlation test-retest reliability was established and was found to be 0.671, which is significant. Face validity and content validity was established. Inter-scale comparison is also illustrated. Five groups formed and their cut of points is also discussed.


A SWIR FPA was designed and manufactured with 640*512 pixels, 20 μm pitch and InGaAs detectors for electroluminescence characterization and astronomical applications in the [0.9 – 1.55 μm] range. The FPA is mounted in a liquid nitrogen dewar and is operated by a low noise frontend electronics. One of the biggest problem in designing sensors and cameras for electro-luminescence measurements is the autoillumination of the detectors by the readout circuit. Besides of proper shielding of the detectors, the ROIC shall be optimized for minimal electrical activity during the integration time of the very-weak signals coming from the circuit under test. For this reason a SFD (or Source Follower per Detector) architecture (like in the Hawaii sensor) was selected, resulting in a background limited performance of the detector. The pixel has a (somewhat arbitrary) full well capacity of 400 000 e- and a sensitivity of 2.17 μV/e-. The dark signal is app. 1 e-/pixel/sec and with the appropriate Fowler sampling the dark noise lowers below 5 e-rms. The power consumption of the circuit is limited 2 mW, allowing more than 24 hours of operation on less than 1 l of liquid nitrogen. The FPA is equipped with 4 outputs (optional readout on one single channel) and is capable of achieving 3 frames per second. Due to the non-destructive readout it is possible to determine in a dynamic way the optimal integration time for each observation. The Cougar camera is equipped with ultra-low noise power supply and bias lines; the electronics contain also a 24 bit AD converter to fully exploit the sensitivity of the FPA and the camera.


In relative terms, however, Australia and Canada trump the United States as immigrant nations: about one in four Australian residents are foreign born, compared with 19 percent for Canada, 12.5 percent for the United States and nine percent for the UK (Walsh, 2008; GMF, 2009; Freeman & Birrell, 2001).


Identification of endoscopic signs of concomitant pathology of the upper gastrointestinal tract allows to determine the tactics of managing patients with different forms of portal hypertension (PG). The analysis of macroscopic picture of esophagus, stomach and duodenum mucosa was carried out in 104 patients with portal hypertension (88 patients with hepatic  portal hypertension, 46 – with extrahepatic portal hypertension, 16 – without  portal hypertension). The frequency of changes in the esophagus, specific for  gastroesophageal reflux disease did  not differ significantly in the researched groups. The frequency and severity  of varicose veins of the esophagus were diagnosed more often in patients with hepatic form of portal hypertension (OR=10.0, p<0.05). The predominance of different pathological changes of the gastric mucosa in patients with extrahepatic form of portal hypertension was revealed. Portal gastropathy in this group was 5.3 times higher than in patients with hepatic hypertension and 21 times higher than in the III group (without portal hypertension) (p<0.01). There were no significant differences of endoscopic picture of the duodenum  mucosa between the researched groups.


Oxigen in the water is obtained from 2 processes specifically the first is, photosynthesis by water plants and the second is aeration which included in the diffusion process. Aerator is a device that serves to produce oxygen through the diffusion process for the needs of living creatures in the water. Aerators themselves have several types, those are ; gravity aerator (gravity influence), surface aerator (surface), diffusier aerator (mixing), turbine aerator (windmill), and combination. The aerators which designed here are aerator type of turbine (turbine aerator) similar to the aerator used in the research area generally. The purpose in the making of an aerator with this automatic system is to simplify the management and also to reduce the operational costs of the ponds. Aerator is made using 2 pieces of waterwheel with each pin having the same 6 blades with a mill used in ponds at the research site. As the basis of the automation system, the aerator is a smart relay programmed with 2 input which are the light sensor and the sensor temperature parameters in the programming obtained from the results of research on dissolved oxygen levels in the water. From the results of the testing, when dissolved oxygen levels are relatively high in the range of 30mg/L light intensity > 100,000 lux and for temperature 350 C.


Based on several in situ observations, the species Ptereleotris calliura (family Gobiidae) and Liopropoma rubre (family Serranidae) are added to the taxonomic fish inventory of the Veracruz reef system, Mexico. While P. calliura was found on sandy substratum in the lagoon, L. rubre was detected on the reef slope. With their addition, the checklist of reef fishes in the Veracruz reef system is expanded to 479 species. Given these findings, we predict that additional survey efforts (beyond visual transects) will reveal more previously unrecorded species of cryptic fishes in the Veracruz reef system.


Soil organic matter is the basis of soil fertility,and also controls the balance of CO2 in the atmosphere and the environmental behavior and biological effectiveness of nutrients,heavy metals and persistent organic pollutants(POPs) in Earth's surface environment.Therefore,it is necessary to pay attention to the process of stability of organic matter.This paper dealt with the mineralogical mechanism of soil organic matter stability by studying the crimson soil profile in Conghua,Guangzhou City.The following processes were carried out: determination of the basic properties of the soil,including pH and mechanical components;determination of total organic matter content and stable organic matter content by potassium dichromate oxidation;determination of the mineral stable organic matter content by TOC analyzer;extraction of free iron oxide with dithionite-sodium citrate;extraction of amorphous iron oxide with ammonium oxalate buffer;determination of iron content by atomic absorption spectrophotometry;XRD semi-quantitative determination of the composition and content of clay minerals;and the correlation analysis between organic matter and mineral.The results indicate that the content of total organic matter,stable organic matter,mineral stable organic matter and recalcitrant organic matter is reduced with the increase of depth.Mineral stable organic matter is mainly existent in the middle layer of soil,while iron oxide minerals mostly occur in the upper soil.The content of kaolinite is dominant(58.7%~84%),the content of smectite is relatively high(8.5%~16.8%);besides,there exists much gibbsite.The content of smectite decreases with the increasing depth,whereas the content of kaolinite and gibbsite increases with the decreasing depth.The correlation between organic matter content and iron oxide mineral is much higher than that between clay mineral and gibbsite.Soil organic matter content and amorphous iron content are much better than the free iron content in the correlation.For instance,there is positive correlation between organic matter and amorphous iron(R20.9),there is positive correlation between organic matter and smectite(R2=0.6971),and there is negative correlation between organic matter and kaolinite,gibbsite [R2(kaolinite)=-0.681 2,R2(gibbsite)=-0.049 8].Obviously,the amorphous iron plays a vital role in the stabilization of soil organic matter;nevertheless,the specific surface area of amorphous iron will limit the capacity of the soil C sequestration,and the adsorption capacity will gradually become smaller until saturation.So we should pay more attention to the mineralogical mechanism of soil organic matter stability and influencing factors.


In this paper, we implement Granger causalty tests using panel data as methodology perfected by Hurlin (2004, 2005) and Hurlin and Venet(2004). We consider the bilateral trade patterns of the European Union with 17 countries over the period 1976-2000. We show that for the whole sample, there are no-causal relationship whatever the lag considered. However, we find some causal relationship from the economic distance to the share of intra-industry trade in the sub-sample of emerging countries and the inverse relationship in the sub-sample of developing countries.


A method and apparatus are described including multicasting a medium reservation message, receiving responses to the medium reservation message and determining if a ratio of the received responses to an expected number of responses exceeds a threshold. Also described are a method and apparatus including receiving a medium reservation message, determining if the medium reservation message specifies this receiver in a list of receivers from which a response is requested, determining if a medium is idle and transmitting the response to the medium reservation message responsive to the second determination.


CoRe is one of the Pedagogical Content Knowledge (PCK) representation that it important for pre-service chemistry teacher. This study aimed to analyze the correlation among pre-service teachers' understanding of curriculum (UC), understanding of context-based learning (UCB), self-efficacy (SE) and the ability for designing Content Representation context-based chemistry (CoRe-CBC). A correlational study was conducted on 41 pre-service chemistry teacher of postgraduate program. Pre-service teachers' understanding of curriculum was assessed using a 30-item of multiple choices. The 6-open ended questions were used to measure the understanding of context-based chemistry learning. Students' self-efficacy was assessed by a questionnaire with 18 items. A group of experts confirmed the construct and face validity of all the instruments. Data analysis used Pearson correlation and regression. The result showed a high correlation between UCB and ability for designing the CoRe-CBC also with UC. A low correlation occurred between UC and the ability for designing CoRe-CBC. The variable of UCB had the biggest effect on the pre-service teacher ability for designing CoRe-CBC. However, the pre-service chemistry teacher still had less understanding in context-based chemistry learning. This study suggests that pre-service teachers' understanding of curriculum and context-based chemistry learning should be improved. It will useful to support the implementing context-based chemistry learning.


Using a field experiment for the period 2008–2009, we examine the impact of ethnicity on women's labour market outcomes four years after the national adoption of the European Racial and Employment Equality Directives. The estimations lead to the observation that ethnic women face a lower chance of occupational access than comparable Greek women, while, ethnic women's wage offers are also discriminatory. The estimations suggest that there is segregation and crowding which refers to the fact that ethnic and Greek women face different chances of occupational access based on jobs' status. Whilst, ethnic women's easier access to low-status jobs entails lower wages for them. Interestingly, however, ethnic women gain by providing information about themselves to employers. On average, distastes against ethnic women are discussed and appear to explain the biases found here. The segregation pattern of ethnic women in low-status jobs and employers' statistical motivations are also found to influence their labour performance.


It provides a sol of tin oxide composite colloidal particles, a hard coating agent, and the optical member is applied to the surface of a production method, a plastic lens-stable zirconium oxide. The present invention is a zirconium oxide-jolyimyeo, the zirconium oxide containing colloidal particles (A) tin oxide composite material - and the oxide ratio SnO In another aspect, the present invention is a silicon-containing material (S) and zirconium oxide consisting of an organic silicon compound and a hydrolyzate - has cured film formed from a coating composition and a coating composition containing a sol comprising tin oxide composite colloidal particles (A) an optical member. Zirconium oxide, tin oxide, colloidal particle, a plastic lens, a hard coating agent, the optical member


NOTE: Page 135 has duplicate pagination. Pages 127, 134, and 147 have been removed by Dr. Lederberg and reconstituted as part
 of his laboratory notebook, "Enzyme Experiments."


Integration of wind energy has (at least) two direc t effects on electricity wholesale markets. First, once wind capacity is installed, its generation cost is negli gib e compared to the costs of balancing power by c onventional generators in real-time. Therefore, when available, wind energy is used before conventional units whic h suppresses real-time prices (Botterud, et al. 2010, Nicholson et al. 2010, Olsina, et al. 2007, Traber and Kemfer t 2011, and Woo et al. 2011). Second, the intermittent nature of wind e ergy increases the frequency with which the outpu t of conventional units is adjusted, thereby increasing operational c osts of generators (see for example Hiroux and Sagu an 2010, Vandezande et al. 2010). One unintended impact of public support for investm ents in wind energy is that spot prices may be depr essed to a point that market incentives to invest in conv entional generators are too low (Olsina, et al. 200 7; Traber and Kemfert 2011). In the presence of market power, the picture is quite different. Twomey and Neuhoff (20 10) show that the emergence of wind energy in the form of fringe capacity allows large firms to amplify the effect o f intermittent supply on market prices. This result is caused by l arge firms depressing prices when they need to buy back energy and increasing prices from their conventional units whe n wind power supply is low. Green and Vasilakos (20 10) provides empirical support for this result, showing that con ve tional generators gain more than wind power prod ucers as market concentration increases. Policies that prioritize wind energy over conventio ally-generated electricity are designed to promote deployment of renewable energy resources. But the f easibility of continuing such policies at high wind penetration rates is unclear. Under these circumstances, we ask which pr ing method for wind power can be implemented t o promote market efficiency? In particular, we compare day-ah ead electricity premiums as wind power capacity exp ands for two central pricing mechanisms for wind energy; real-ti me balancing market and a Feed-In-Tariff (FIT) arra ngement.


This study numerically investigated the influence of using the second row of a double-row deswirl vane as the inlet guide vane of the second stage on the performance of the first stage in a two-stage refrigeration centrifugal compressor. The working fluid was R134a, and the turbulence model was the Spalart-Allmaras model. The parameters discussed included the cutting position of the deswirl vane, the staggered angle of two rows of vane, and the rotation angle of the second row. The results showed that the performance of staggered angle 7.5° was better than that of 15° or 22.5°. When the staggered angle was 7.5°, the performance of cutting at 1/3 and 1/2 of the original deswirl vane length was slightly different from that of the original vane but obviously better than that of cutting at 2/3. When the staggered angle was 15°, the cutting position influenced the performance slightly. At a low flow rate prone to surge, when the second row at a staggered angle 7.5° cutting at the half of vane rotated 10°, the efficiency was reduced by only about 0.6%, and 10% of the swirl remained as the preswirl of the second stage, which is generally better than other designs.


To the Editor.— In a recent commentary by Dr Crosby 1 entitled "Whatever Became of Chlorosis?" the author implies that chlorosis has not only vanished from the practice of medicine but disappeared from the medical literature as well. Having noted the mass of citations on chlorosis in the 1881 edition of the Index Catalog of the Library of the Surgeon General's Office U.S. Army, the author states that "one hundred years later, in 1981, Index Medicus [ IM ] contains none, not one, no listing at all. Chlorosis is gone from IM because it is gone from the practice of medicine." Although chlorosis has faded from the modern hospital ward and even from the pages of the 1981 edition of IM , references to the disease still appear in the literature. A search of the National Library of Medicine's MEDLINE database for the year 1981 reveals four articles 2-5 (concerning the disease in


Abstract: In 1917, Josep Masdeu, the monastery archivist of Sant Joan de les Abadesses, identified four songs written down in some blank spaces of a paper-based notarial book of the village. In 1935, Higini Anglès, a musicologist of recognized prestige, made them public and since then, they comprise the songbook of Sant Joan de les Abadesses, the unique troubadour catalogue in Catalonia including both the text of the songs and their equivalent musical notation to be performed. From that moment on, the manuscript has been studied in many occasions from a linguistic and musical point of view. The manuscript, currently preserved at the National Library of Catalonia, includes some other text passages of legal topics which we analyse in depth because they delimit the exact chronological period of the song writings. Our study, therefore, has been focused on three main purposes. In the first place, we revise the contributions made so far regarding the description of the document. Next, we build up the archivistic history of the manuscript, from the moment it was discovered until it was deposited in the library mentioned above. Finally, we frame the overall context of the songbook production based on the extraliterary and extramusical texts.Keywords: Troubadour songs, Medieval manuscripts, Medieval songbook, Sant Joan de les Abadesses Archive, Court books, Notarial -History.


The nominal bunch length is around 10 ps rms in the Taiwan Photon Source (TPS). To further reduce bunch length to a few ps rms range, low momentum compaction factor configurations (low alpha), i.e., quasi-isochronous machines, are designed. The beam dynamics issues of the TPS low alpha lattice are reported.


Buddhist Apocryphal Scriptures are a kind of special scriptures which correspondent with Chinese society. On the found of inherited the thought of tradition Buddhism, they also merged and mixed with the thought of Confucianism and Daoism. Viewed from the thought of Chinese Buddhist Apocrypha we can find how the Buddhism became the important belief form of Chinese common people. It is the result of inhert and transcend of the thought of Buddhism.


Molecular characterization of the mitochondrial DNA [mtDNA] from the etiolated pearl millet [Pennisetum glsucum (L.) R. Br.] seedlings of cytoplasmic male sterile (CMS) line having A1 cytoplasm alongwith Its maintainer, restorer and restored lines of hybrid RHRBH-8609 (Shradha) revealed polymorphism by 10 RAPD primers. Only four primers showed polymorphism between a CMS, RHRB-1A and Its fertile Isonuclear line, RHRB-1B. However, 5 primers showed polymorphism between the CMS line and its restorer line, RHRB-138R. The primers OPC15, OPC16 and OPG13 generated fragments of ∼3.90 kb, 1.59 kb and 1.02 kb size only In the mtDNA of a male sterile line which might be associated with the CMS phenotype of RHRB-1A in pearl millet.


Author(s): Pandey, Anshuman | Abstract: This is a Unicode proposal to encode six additional Gujarati script characters into the international character encoding standard Unicode. The six characters published in Unicode 10.0 in 2017. The characters were used for the transliteration of Arabic into the Gujarati script.


This paper focuses on disagreement between theoretical predictions and the SELEX results of the production properties of Doubly Charmed Baryons. The role of the intrinsic charm mechanism in the SELEX kinematic region is researched. The production ratio of the $\Xi_{cc}^+$ baryon in the SELEX kinematic region is presented. The recent experimental results are reviewed.


Life skills education was introduced by the Kenya government to replace the HIV and AIDS education which was not positively perceived by its implementers. The purpose of this study was to investigate Secondary schools' readiness towards the implementation of life skills education in Trans-Nzoia County. The main objectives were to determine teachers' training on life skills education implementation in Trans-Nzoia County, to assess the availability of teaching and learning materials and infrastructure for the implementation of life skills education in Trans-Nzoia County, to evaluate teachers' attitude towards the implementation of life skills education in secondary schools of Trans-Nzoia County, and to establish school management attitude towards the implementation of life skills education in secondary schools of Trans-Nzoia County. The study was guided by Work readiness theory by Catherine, Walker, Mathew and Cathy. This study employed concurrent triangulation study design with mixed methodology, where a target population of 2,234 teachers was studied. The study used concurrent sampling technique. Probability sampling with a simple random sample was used to sample thirty percent of schools. It further purposively sampled out thirty percent of secondary schools principals, deputy principals, guidance and counselling heads of department and teachers assigned to teach life skills who participated in the study. Instruments of data collection included interview schedule, observation guide and document analysis guide. A pilot study was carried out to establish the reliability of research instruments. Data was analyzed descriptively and thematically. The study was significant in contribution to the formulation of policies for life skills education in secondary schools, recognition of life skills education in the development of the nation by the stake holders, consideration of school management and teacher factors that are related to the teaching of life skills education by curriculum developers and also serve as a reference material to potential researchers in the related field of study. The findings of the study indicated inadequate training of teachers in life skills education, inadequate use of teaching learning materials, some element of unwillingness by teachers in the implementation of life skills education in secondary schools of Trans-Nzoia County. There was also inadequate supervision and support towards teachers by administrators towards the implementation of life skills education in Secondary schools of Trans-Nzoia County. The recommendations were that the government should put a policy in place as an affirmative action to train teachers in the implementation of life skills education. Kenya Institute of Curriculum Development should review the implementation programme in terms of time and curricular and nationally evaluate the subject.


change, although the fall of diastolic blood pressure was less than that of systolic blood pressure. Both IV and sublingual nitroglycerin brought about an increase in heart rate (Figure 2). By sublingual nitroglycerin, heart rate gradually increased to the maximum value of 80 beats/min after 10 minutes and then slowly decreased to almost the same value as the control after 20 minutes. With IV infusion of nitroglycerin, heart rate quickly increased in the initial five minutes to 77 beats/ min from 71 beats/min and was kept almost constant throughout the infusion until the cessation of the drug. The rate-pressure product was significantly decreased at five minutes and showed little change thereafter. In two cases of nitroglycerin infusion that were on other antihypertensive agents, a rapid fall of blood pressure was encountered, which was recovered with brief treatments. No other serious complications were experienced with either method of nitroglycerin administration.


Cross-modal analysis is a natural progression beyond processing of single-source signals. Simultaneous processing of two sources can reveal information that is unavailable when handling the sources separately. Indeed, human and animal perception, computer vision, weather forecasting, and various other scientific and technological fields can benefit from such a paradigm. A particular cross-modal problem is localization: out of the entire data array originating from one source, localize the components that best correlate with the other. For example, auditory and visual data sampled from a scene can be used to localize visual events associated with the sound track. In this paper we present a rigorous analysis of fundamental problems associated with the localization task. We then develop an approach that leads efficiently to a unique, high definition localization outcome. Our method is based on canonical correlation analysis (CCA), where inherent ill-posedness is removed by exploiting sparsity of cross-modal events. We apply our approach to localization of audio-visual events. The proposed algorithm grasps such dynamic audio-visual events with high spatial resolution. The algorithm effectively detects the pixels that are associated with sound, while filtering out other dynamic pixels, overcoming substantial visual distractions and audio noise. The algorithm is simple and efficient thanks to its reliance on linear programming, while being free of user-defined parameters


ABSTRACT The goal of this research is to describe and find out the contribution of archive management, storage, and removal to service excellence in PT Pacific Indo Packing. This research invloves 60 PT Pacific Indo Packing employees as the sample. The instruments used in this study are questionnaire, documentation, and interview. The result shows the correlation between archive management, storage, and removal and service excellence, it is shown by F hitung = 4,796 >Ft abel = 2,79, shown Fhitung is bigger than Ftabel which means archive management, storage, and removal are strongly contributed to service excellece in PT Pacific Indo Packing. Key words: Management, Storage, Archive Removal, and Service Excellence


The location of smart sustainable city multi-floor manufacturing (CMFM) directly in the residential area of a megapolis reduces the delivery time of goods to consumers, has a favorable effect on urban traffic and the environment, and contributes to the rational use of land resources. An important factor in the transformation of a smart city is the development of CMFM clusters and their city logistics nodes (CLNs); the key elements of the logistics system of a megapolis. The primary goal of this study was to examine the role of the CLN4.0, as a lead sustainability and smart service provider of a CMFM cluster within the Industry 4.0 paradigm, as well as its value in the system of logistics facilities and networks of a megalopolis. This paper presents an innovative model of a CLN4.0 under supply uncertainty using a material flow analysis (MFA) methodology, which allows for specific parameters of throughput capacity within the CMFM cluster and the management of supply chains (SCs) under uncertainty. The model was verified based on a case study (7th scenario) for various frameworks of a multi-floor CLN4.0. The validity of using a group of virtual CLNs4.0 to support the balanced operation of these framework operations under uncertainty, due to an uneven production workload of CMFM clusters, is discussed. The results may be useful for the decision-making and planning processes associated with supply chain management (SCM) within CMFM clusters in a megapolis.


OBJECTIVES
To observe the relative role of individual and group-level antimicrobial selective pressure on subsequent methicillin-resistant Staphylococcus aureus (MRSA) isolation in a university hospital.

METHODS
For this purpose, 18 596 patients were included in a retrospective statistical analysis, applying multilevel modelling with discrete time intervals at the lowest level. Individual-level and hospital group variables on antimicrobial exposure and MRSA colonization pressure were collected from computerized databases.

RESULTS
The simultaneous hospital group- and individual-level analysis showed individual exposure to fluoroquinolones and collective exposure to penicillins to be associated with MRSA isolation after adjustment for colonization pressure and other potential confounders.

CONCLUSIONS
These results support efforts to reduce prescriptions of selected antimicrobial drug classes such as fluoroquinolones and show the added value of multilevel analysis for research on the adverse outcomes of antibiotic prescribing.