State-of-the-art geophysical technology, requiring access to the biggest and best computer systems in the world, is not beyond the reach of independent oil and gas producers. Working with partners from academia and the US government, Oryx Energy Co. This year completed a seismic procedure that tested the limits of one of the world`s larger computer systems. The procedure, 3D prestack depth migration (PSDM), is the best technique developed so far for imaging salt bodies and subsalt structures. Because it requires massive data processing capacity, PSDM is sometimes seen as an exclusive tool of major oil companies. But Oryx thought that only 3D PSDM could answer questions it had about a recent Garden Banks discovery in the Gulf of Mexico. So the company in 1992 began searching for an alliance through which to make use of then newly commercial 3D PSDM technology. In May 1994, the company signed a cooperative research and development agreement (CRADA) with University of Texas at Dallas (UTD) and Sandia National Laboratories, Albuquerque. The CRADA brought together Oryx`s modeling and programming expertise, a PSDM computer code developed by UTD, Sandia`s Intel Paragon massively parallel processing (MPP) computer, and people and expertise from all three groups. By themore » time the final migration was completed last May 21, Oryx had not only answered many of its geological questions but also tested a pioneering migration technique, become one of the first companies to apply 3D PSDM technology to output a full data volume, worked with its partners to solve several computing problems, and found a way to apply MPP technology without owning an MPP machine. This article describes the computing challenges to be met, the project, and PSDM results.« less


The success in managing the Geopark Cileutuh Sukabumi tour by providing quality services and facilities that can be determined by developing these tourist destinations. Purpose Want to know tourist satisfaction factors and analysis of the most dominant factors in influencing tourist satisfaction Geopark Cileutuh Sukabumi. The population is the guests who stay at the Geopark Cileutuh Sukabumi. Samples were taken as many as 100 tourist respondents using the Non-Probability Sampling technique. The research method used was the Accidental sampling approach, namely the technique of determining the sample based on chance, that is, who happened to meet the researcher can be sampled if deemed suitable. Based on statistical data analysis, the indicators in this study are valid and the variables are reliable. Conclusion on testing the classical assumptions, multicolonierity-free regression model, heteroscedasticity does not occur, and is normally distributed. The order of each individual variable with the most influence is regression coefficient variable 0.316, regression coefficient 0.271, regression coefficient responsiveness 0.201, and regression coefficient reliability of 0.197 while the variable that has the greatest influence, low with a regression coefficient of 0.165. So from these results, the Cileutuh Sukabumi Geopark needs to maintain in terms of service on several components that are considered by tourists to be good and need to fix and improve things that are still lacking in the element of service.


Equilibrium viscosity data at 5C, over a wide shear rate range (10 -5 s -1 -10 3 are presented for a typical commercially available stirred yogurt. A bob in cup and a vane in cup geometry were used in the work. The vane was manufactured to the same outer dimensions as the bob. A series of constant shear stress creep tests was performed, ranging from 2 Pa to 60 Pa. Equilibrium shear rate values were found for each shear stress. Equilibrium viscosity data obtained with both geometries were of the same order of magnitude, This indicated that slip (wall depletion) effects were not significant with the bob in cup geometry used in the study. Application of existing rheological models showed that the equilibrium viscosity behavior of yogurt may be described using either a power-law of the form η=k 1 γ n-1 or the Cross equation 0 =(k 2 γ) m . The Cross model better predicted the almost constant viscosities observed at low shear stresses.


Hydrogel is a versatile material that vastly used in various applications. In this study, the carbon dioxide capture properties of hydrogels were further improved with the infusion of amine. Three types of superabsorbent hydrogel namely polyacrylic acid (AAc), sodium polyacrylate (SAP) and polyacrylamide (AAm) were synthesized via simple solution polymerization with the aid of ammonium peroxodisulphate (APS) as the initiator and N,N'-methylenebis (acrylamide)(MBA) as the crosslinker. Diethanolamine (DEA) loading AAm hydrogel has recorded 0.9 mmol CO 2 captured/ g hydrogel and monoethaolamine (MEA) loading AAm hydrogel has captured 1.7 mmol CO 2 / g hydrogel. An increment up to 2.2 mmol CO 2 captured/ g hydrogel was obtained when the ratio of hydrogel to amine loading was increased to 1:4 from 1:1. In term of regeneration of the adsorbent, this amine infused hydrogels maintained its maximum adsorption capacity until third cycle. The amine infused hydrogel provide a facile platform for developing solid sorbents for CO 2 capture.


This study is concentrated to investigate the effects of aeration and stirring speed on the volumetric mass transfer coefficient (KLa). A dynamic technique was used in estimating KLa values in order to achieve the aim of this study. This study was done in 10L bioreactor by using two medias:1. Dionized water 2. Xanthan solution (1 g /L) Moreover, the research covered a comparison between the obtained values of KLa. The Xanthan solution was used because of its higher viscosity in comparison with water. It behaves similarly to the cultivation medium when organisms are cultivated in a bioreactor. Growth of organisms in the reactor leads to a change in the viscosity of the medium which affects the mass transfer. Two variables, the effect of air flow rate (3-20 L/min) and the effect of stirring speed (250-700rpm) on KLa value were studied. Other parameters such as temperature, liquid volume, and stirrer shape and stirrer position were held constant; the results demonstrated an increase in KLa – value and mass transfer with increasing stirrer speed. Thus at higher speed, better dispersion of the bubbles was obtained. Therefore, that increased the surface / volume ratio which increased the mass transfer area i.e. KLa value.


[Objective]The aim was to screen efficient and low-toxicity insecticides which had good control effect on F.tenuicornis.[Method]Control effects of seven insecticides on F.tenuicornis in field were studied.[Result]The seven tested insecticides could kill the most of F.tenuicornis.The control efficiency of Spinetoram was the highest,and it reached 84.30% three days after treatment,83.30% seven days after treatment and 82.34% 14 days after treatment.The control efficiency of Spinetoram and Cyantraniliprole were both more than 80%,furthermore there was no significance between them.[Conclusion]In is suggested that Spinetoram and Cyantraniliprole could be sprayed at the incipient stage of F.tenuicornis to reduce them.


This is a review of the evidence for exogenous estrogens as causes of endometrial cancer and the use of progestagens on a routine or "challenge" basis to prevent cancer in postmenopausal women. Cancer of the endometrium was proven to be associated with heightened estrogen secretion since the 50s for example in women with polycystic ovary or estrogen-secreting tumors. One oral contraceptive a high-estrogen sequential that has since been withdrawn was associated with endometrial cancer. By the late 70s it was clear that combined oral contraceptives decrease the risk of endometrial cancer to about 0.5-0.6 that of nonusers. This cancer has increased almost 4-fold among premenopausal women in recent years perhaps related to the decline in oral contraceptive use in this group. Endometrial cancer is associated with obesity liver disease nulliparity infertility and perhaps diabetes and hypertension. It is more common in upper class women who have access to medical care and have been prescribed unopposed estrogens after menopause. The authors group enumerated the incidence of endometrial cancer in 5500 menopausal women in a prospective study. The rates were 49/100000 in those taking combined estrogens and progestagens 391 in those given unopposed estrogens and 246 in untreated women. They determined that progestagens should be given at least 13 days per month during estrogen treatment based on the conversion of endometrial hyperplasia to normal by clinical criteria. They recommended that all women be given the progestogen challenge yearly and that those that respond by bleeding advised to take a combined regimen until bleeding fails to occur probably well after age 65. Universal use of the progestogen challenge test should prevent nearly all endometrial cancers.


Detecting of vessels and submarines through their noise analysis should be performed quickly and around the clock. A numerical model for detecting narrowband hydroacoustic signals based on the two stages continuous wavelet transform (CWT) is presented. The first stage of the wavelet transformation can be performed at port before. On the ship board only the second stage of the wavelet transform must be performed. This reduces the computation time and speeds up the detection of enemy ships. Reducing hardware costs for making this apparatus for detecting narrow-band hydroacoustic noise signals based on the two stages CWT are shown.


This paper presents data on the collection, analysis, processing of materials for keeping spawners of the Baikal omul, determining the optimal stocking density of fish in cages, determining the efficiency of using spawners in 2020.


This article is dedicated to examining the difficult cases of the transmission of the indefinite meaning with the indefinite pronouns and adverbs with the affixes -nibud, -libo, -to, koe- among Iranian audiences. The indefinite pronouns and adverbs are a group of words with a specific meaning and usage that express the category of indefiniteness. This topic is important because among the Iranian students learning Russian the use of indefinite pronouns and adverbs with these affixes is a most difficult problem. It is not due to the grammatical features of the pronouns and adverbs mentioned, but due to their dependence on semantic subtleties and the insufficient number of theoretical works analysing the errors made by foreign, including Iranian, students when using the indefinite pronouns and adverbs with the mentioned affixes. The first problem that Iranian students face is the use of the indefinite pronouns and adverbs in the Russian language when in Persian their formal indicator is the indefinite article. The purpose of this article is to study the complicated cases of using the indefinite pronouns and adverbs with affixes -nibud, -libo, -to, koe- with indefinite meaning in the Iranian class and to consider how this group of the indefinite pronouns and adverbs is used in speech and text. The novelty of this article is in the fact that for the first time in the Russian studies of Iran, the difficult cases that Iranian students often encounter when using the indefinite pronouns and adverbs with affixes -nibud, -libo, -to, koe-, are analyzed and specified. In addition, principles have been developed to optimize the teaching process of this category of pronouns and adverbs among Iranian students. The results of the article can be used to eliminate the mistakes of Iranian students of Russian when using the indefinite pronouns and adverbs with the affixes -nibud, -libo, -to, koe- with the indefinite meaning, as well as to improve teaching Russian as a foreign language in the Iranian audience.


: The article focuses on the current trend of modern law enforcement activity - profiling. Profiling is considered in it with the help of hermeneutic, comparative, legal comparative and a set of logical methods, primarily in the operational-search, as well as other areas of law enforcement. Goal of the article: analysis of the available recommendations for the profiling implementation in law enforcement and the development of proposals for identifying certain types of compiling a psychological profile of a person, as well as justifying the need to use profiling methods. To achieve this goal, the authors solved the following tasks: differentiation of profiling types in law enforcement, emphasizing the need for professional training and obtaining relevant competencies for the effective performance of profiling. Taking into account the digitalization trends in all spheres of activity, both digital profiling (search for a person using open sources and electronic databases according to the given characteristics of a digital profile) and the use of hardware-software and software systems in the course of operational-search profiling during operational-search activities related with personal verbal and/or eye contact with the object. Basics of the tactics of such use of digital technologies in operational-search and investigative activities are considered. The authors suggest specific innovative directions as conclusions: in terms of practical law enforcement structures enrichment with relevant specialists; in terms of using profiling for general and private crime prevention; in terms of digitalization of investigative and operational-search activities related to digital profiling.


CNC system is involved in multiple fields of complex systems,and the machine itself variety,different function,structure style is varied also,Numerical control system fault diagnosis becomes more difficult.In order to solve this kind of problem,for some of the commonly used numerical control system fault diagnosis technology is introduced,that machine repair personnel to provide useful reference.


To report a 53-year-old female patient suffering from CSH (Cutaneous sinus hietocytosis). The purely asymptomatic cutaneous lesions on her submaxilla and cheek were the only clinical manifestation. Histologically, the lesions were marked by characteristic variable numbers of pale-staining histocytes with emperipolesis overshadowed by extensive lymphoplasmacytic infiltrates in the background. By immunohistochemmical analysis, the characteristic histocytes were positive for S-100 protein and CD68, negative for CD1α. treatment with submaxilla seemed ineffective in this case.


It is essential to avoid two misconceptions: "teaching can naturally i mprove with better teaching facilities," and "multi-media presentation can be a replacement of everything." in using multi-media presentation and improving teac hing quality, Attention should also be given to three issues-unbalanced between construction and application of multi-media facility, laggard management, and ab using of multi-media. In preparing and applying multi-media presentation, one sh ould be aware of the functions and purpose of the presentation, set reasonable t arget and abide by "unity of four qualities" and "eight principles".


14.00 This article presents an alternative proposal of executive and manager development that should occur in consonance with the context where executive and managers work. It is suggested a substantial review in the role of the professionals and sectors of Human Resource Development in planning and implementing Executive and Manager Development Programs . Actual1y these programs are calling for a modification in content and methodology in terms of being closer to organization reality. In order to be more effective these programs should inspire themselves in Lindblom's incrementalism, that is, follow the rhythm of events, back and forth, but going toward a better performance. The author suggests that some essential features should be emphasized in those training programs: the chain of executives and managers relationships in the organization (with the immediate superior, with the middle levels, staff and technical people), the projects and other organizational activities, the progressive competencies in management, the job rotation. Normal 0 21 false false false PT-BR X-NONE X-NONE /* Style Definitions */
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GENERAL problem that calls £or discussion, and hopefully will be treated in the deliberations of the Second Vatican Council, is that of the relationship of moral theology to recent innovations in philosophy. Several papal directives and encyclicals have already discussed moral problems and attempted to rectify errors of the " new theology " associated with these innovations, pointing out in the process more fruitful ways toward a renewal of moral theology.1 Such problems, while not merely of academic interest-affecting as they do the moral life o£ all Christians-are nonetheless of major concern to those who teach moral theology in universities and seminaries. A representative teaching in this category which merits examination is that known in German-speaking countries as Existentialethik and coming to be known here as " existential ethics." 2 Its importance derives not only from its subject matter but also from the fact that it is cited as a fruitful application o£ modern knowledge to the development of theological science. In this article we propose to explain this development and evaluate it from the viewpoint o£ the teacher of moral doctrine. The seminary professor, and to a lesser extent the professor in a Catholic university, is torn between two extremes. On the one hand, he is committed to transmitting the theological tradition of the Church to those he teaches, a task difficult in


The tooth thickness of involute gear is controlled by common normal length measured.For single point-line meshing gear,the wheel is a large negative X-gear.Involute profile is short.Its common normal length is not measured.When mode number is big in a single point-line meshing gear,it is difficult that normal line length is measured.In this page,two kinds of measuring tooth thickness method are put forward,including measuring normal line length and measuring normal tooth thickness and tooth depth of J point(crossing point between involute curve and transition curve).They are used to control tooth thicknesses of small and medium mode number and big mode number single point-line meshing gear.Calculation formulas are given.They are validated through a example.


We use coupling ideas introduced in \cite{levine2018long} to show that an IDLA process on a cylinder graph $G\times \mathbb{Z}$ forgets a typical initial profile in $\mathcal{O}( N\sqrt{\tau_N} (\log \! N)^2 )$ steps for large $N$, where $N$ is the size of the base graph $G$, and $\tau_N$ is the total variation mixing time of a simple random walk on $G$. The main new ingredient is a maximal fluctuations bound for IDLA on $G\times \mathbb{Z}$ which only relies on the mixing properties of the base graph $G$ and the Abelian property.


Background: Most local anesthetics decrease neuromuscular transmission and potentiate the neuromuscular blocks of muscle relaxants. The purpose of this study was to examine the influence of lidocaine on it effects rocuronium onset and intubation conditions in rapid-sequence intubation and to compare with those of succinylcholine. Methods: Seventy five ASA physical status 1 and 2 patients were randomly allocated to three groups. Group S received succinylcholine (1.0 mg/kg), Group R received rocuronium (0.6 mg/kg) and additional lidocaine (1.5 mg/kg) was given intravenously prior to the administration of rocuronium 0.6 mg/kg in Group RL. Anesthesia was induced with midazolam 0.03 mg/kg, fentanyl /kg, and thiopental 5 mg/kg. Intubation was performed 60 seconds after the administration of muscle relaxants and intubation conditions were evaluated. Neuromuscular blockades were assessed by single twitch responses of the adductor pollicis after ulnar nerve stimulation by accelerography (0.1 Hz, 0.2 ms supramaximal stimuli). Results: The onset time of Group S (47.811.3) was shorter than those of Group R (87.8 30.2) and Group RL (75.421.5), but no differences was observed between the onset times of Group R and Group RL. Intubation conditions were good or excellent in all groups. Conclusions: Additional lidocaine to rocuronium neither influences intubation condition nor accelerate the rocuronium onset, and it is cannot be viewed as an alternative for succinylcholine in rapid-sequence tracheal intubation.


I will be discussing the problem of sketch understanding which, as we shall see shortly, involves much more than just recognizing sketched symbols. Most of the work that I will present has been done by myself and the other members of my former research group back at MIT, lead by Professor Randy Davis. In addition, I would like to acknowledge my current team of undergraduate researchers who are helping me explore these problems further.


With the electronic equipment more compact structure,more and more high-density assembly and increasing power,the cooling problem is getting worse,the traditional thermal design techniques have been very difficult to meet their requirements,designers should be actively tracking and applying new thermal design techniques to meet the needs of modern electronic equipment.In this paper,the working theory of new inorganic element of transmitting heat is expounded in detail,its effect of transmitting heat is verified,and an applied example is given.They can be reference to those engaging in developing military electronic equipment.The new inorganic element of transmitting heat can resolve the cooling problem of big power and sealing equipments effectively,ensure their working stability and improve their reliability.


The lowest temperature was 19.3 K and 60.4 W at 48.5 K in a GM type pulse tube cooler in which the double-inlet mode was consist of two parallel-placed needle valves with opposite flow direction instead of conventional single-valved configuration. In recent experiments a new phenomenon, temperature loop, was found when the cooler working in orifice mode. This phenomenon depends on the heat load and on the adjustment of the needle valve connecting the pulse tube warm end with the buffer volume. It will give a new way to understand the temperature instability which sometimes happens in double-inlet mode of pulse tube cryocoolers.


The sheet conveyance apparatus includes a controller which controls a moving unit. The moving unit moves a sheet conveyance unit for conveying a sheet toward a direction intersecting with a sheet conveyance direction. The controller performs the control such that a moving speed of a shift moving unit is reduced when a shift amount of the sheet discharged from an image forming apparatus main body is small. Therefore, generation of a noise and vibration can be suppressed to save electric power consumption. When the shift amount of the sheet is large, the moving speed of the shift moving unit can be increased to shorten an operation time necessary to the movement.


Actuality of the problem. The Sverdlovsk Region is a region with a high incidence of HIV infection, occupying a leading position in the Russian Federation for several years. The increase in the number of people who have HIV infection inevitably leads to an increase in the number of people contacting them and the creation of discordant couples. However, the issue of prescribing pre-exposure prophylaxis with antiretroviral drugs for this group of people has not yet been resolved and is not being used as an active prophylactic measure. The results of our study showed a higher risk of contact with male sources compared to female sources, as male sources were characterized by an increased frequency of substance use and a higher viral load. Primarily identified HIV infected women are essentially contact, and men who infect them are identified later as a result of an epidemiological investigation. It is necessary to actively identify individuals who are in contact with HIV infected patients and apply pre-exposure prophylaxis, especially among consumers of psychoactive substances and their partners. Identification of resistant discordant pairs, regardless of the source of infection (male or female), should be an indication for the appointment of each HIV infected ARV therapy, and each contact — ARV-prevention. Implementation of this approach requires revision of the standards of medical care for HIV infected persons and the development of standards for the appointment of ARV prophylaxis to their contacts.


The main objective of this interview with Professor Rodrigo Duarte is to share with the readers of the journal Opiniao Filosofica an important date: the seventieth anniversary of Horkheimer and Adorno's Dialectic of Enlightenment, written in California in 1944, but published in 1947 by Querido Verlag in Amsterdam. Although almost seven decades have passed since the publication, bringing the emergence of new types of social life, new formal features in cultural life and the consolidation of a new world economic order still remain highly topical. Duarte, an Adorno scholar from Brazil, shows that the concepts of the German philosopher are a valid source of knowledge in order to substantiate a critique of the contemporary culture


Punch for forming square socket type head for screw fasteners in which the socket has four equal sides each of which has an upper slightly inwardly inclined flat portion which merges without discontinuity at its lower end with a lower concave bottom portion.


Intratumoral androgen biosynthesis has been recognized as an essential factor of castration‐resistant prostate cancer. The present study investigated the effects of curcumin on the inhibition of intracrine androgen synthesis in prostate cancer. Human prostate cancer cell lines, LNCaP and 22Rv1 cells were incubated with or without curcumin after which cell proliferation was measured at 0, 24, 48 and 72 hours, respectively. Prostate tissues from the transgenic adenocarcinoma of the mouse prostate (TRAMP) model were obtained after 1‐month oral administration of 200 mg/kg/d curcumin. Testosterone and dihydrotestosterone concentrations in LNCaP prostate cancer cells were determined through LC‐MS/MS assay. Curcumin inhibited cell proliferation and induced apoptosis of prostate cancer cells in a dose‐dependent manner. Curcumin decreased the expression of steroidogenic acute regulatory proteins, CYP11A1 and HSD3B2 in prostate cancer cell lines, supporting the decrease of testosterone production. After 1‐month oral administration of curcumin, Aldo‐Keto reductase 1C2 (AKR1C2) expression was elevated. Simultaneously, decreased testosterone levels in the prostate tissues were observed in the TRAMP mice. Meanwhile, curcumin treatments considerably increased the expression of AKR1C2 in prostate cancer cell lines, supporting the decrease of dihydrotestosterone. Taken together, these results suggest that curcumin's natural bioactive compounds could have potent anticancer properties due to suppression of androgen production, and this could have therapeutic effects on prostate cancer.


Morbidly adherent placenta occurs due to the imperfect development of netabuch's layer. Depending on the extent of adherence and invasion of the placenta, the condition is classified as placenta accreta (reaching the myometrium), placenta increta (into the myometrium) or placenta percreta (reaching up to serosa and beyond to surrounding structures). It is often associated with placenta previa. When placenta previa was present, the risk of morbidly adherent placenta increased from 24% for a patient with one previous cesarean delivery to 67% for a patient with three or more cesarean deliveries. Specifically, placenta percreta is associated with high maternal morbidity and as much as 7% maternal mortality. ABSTRACT


Several tramp ant species are found in the city of Barcelona (Espadaler & Collingwood 2001 and references): Lasius neglectus, Pheidole teneriffana, Paratrechina flavipes, Hypoponera punctatissima and Linepithema humile. Only the last species, the argentine ant, attains pest status in the city at present. To that small group we can now add a sixth species, the ghost ant, the first time it has been recorded in the Iberian Peninsula. Within the Iberian Tapinoma species, this ant is easily distinguished by its highly distinct bicoloured habitus (Fig. 1), with the yellowish gaster, legs and antennae, contrasting with the dark head and thorax. See Shattuck (1994): 147-148 for a complete historical taxonomic history and supplementary references. The ghost ant (Tapinoma melanocephalum) is a well known tramp species widely dispersed by human trade mainly throughout humid tropical regions (Williams 1994), although it has also been detected in the climatically much drier Arabic Peninsula (Collingwood & Agosti 1996; Collingwood et al. 1997). Its origin is unknown (Wilson & Taylor 1967). Isolates have been found outside the tropics, probably carried with plant material or products from the tropics. Outside this region, it seems to thrive only in heated buildings (DuBois & DanoffBurg 1994) or inside structures (Klotz et al. 1995). Nests are usually difficult to locate and it is generally perceived as a nuisance (Harada 1990). This ant seems to be currently extending its range. In Europe it has been found in places with a high degree of humidity and temperature, as in kitchens and bathrooms of hospitals or restaurants and in suitable zones in zoological gardens and greenhouses. Previously known European localities were Germany (Scheurer 1984; Steinbrink 1987; Scheurer & Liebig 1998), Great Britain (Williams 1956; Shah & Pinniger 1996), Russia (Kunashev & Niyazova 1998) and Switzerland (Dorn et al. 1997). Tapinoma melanocephalum (Fabricius, 1793), a new exotic ant in Spain (Hymenoptera, Formicidae)


Patterns in the amount of RNA and DNA in six species of larval fish in Conception Bay, Newfoundland, are studied. As the amount of DNA increases, the distribution of the ratio of RNA to DNA contracts towards its highest values. This is interpreted to mean that RNA/DNA is an indication of survival probability, and that survival probability is a quantity that tends to persist through a larva's life. Comparisons among species indicate that the greatest degree of contraction (the strongest selection pressure) is associated with the highest mortality rates. There is evidence that variability in RNA/DNA is introduced around the time of yolk-sac absorption.


ON November 7, 1985, the Journal published the results of a randomized trial of extracranial–intracranial (EC–IC) arterial bypass surgery to reduce the risk of ischemic stroke in patients with symp...


The principles of planning the reproduction of fixed assets of the rocket and space industry enterprises are investigated, taking into account the features of their activities and the requirements for strategic planning.


Simply defined, metonymy is a phenomenon in which two things are associated, so that one thing stands for the other, i.e. the source stands for the target. (Evans and Green, 2006, p. 314; Barcelona, 2003) The example from Evans and Green (2006, p.  312) is "England beat Australia in the 2003 rugby World Cup ?nal." In that example, England and Australia stand for their own national football teams. The example is whole-for-part metonymy. Generally classified, the types of metonymy are whole for part and part for whole. (Barcelona, 2003, p. 239) What it means by "whole for part" is a general thing represents a specific thing. It goes the other way around for "part for whole". As everyone uses metonymy very often, it is everyone's awareness towards metonymy that should be increased. Metonymy is a powerful tool (Guan, 2009, p.  179). It is a "cognitive tool for people's conceptualization of the world" (Guan, 2009, p.  179) and particularly "for guiding inferencing in the interpretation of spoken discourse" (Kriskovic & Tominac, 2009, p.  50).


We report herein a case of primary cutaneous zygomycosis caused by Rhizopus oryzae in a 7‐year‐old girl with acute lymphoblastic leukemia (ALL) receiving intensive chemotherapy. The diagnosis was based on observation of hyphal elements in cutaneous biopsy and isolation of the fungus in culture. The patient responded to surgical intervention and treatment with amphotericin B.


This research seeks to understand local planners" attitudes and practices concerning parking requirements for workplaces. Parking requirements are receiving increasing attention as a crucial element of transportation and land use policy, and there are many critiques of excessive minimum parking requirements. Researchers and policy makers are advocating that cities rework their parking requirements to serve broader goals concerning transportation, land use, economic development, and sustainability. In 1995, a research team surveyed local jurisdictions in Southern California to understand the perspectives of the planners who create workplace parking requirements. This research replicates the original research design to identify current perceptions and to see if they have changed since 1995. This study was limited to workplace parking issues. The survey was conducted in spring 2013, inviting 169 jurisdictions across Southern California to participate, from which 50 completed surveys were received. Survey responses show that planners continue to see their role as ensuring an "adequate" number of parking spaces are provided, but indicate that determining the appropriate number of spaces is a significant issue. The most common request from developers is to reduce on-site parking supply. Use of precedent and national data sources continues to outpace local utilization surveys in setting requirements. Survey responses show planners" recognition of the role of parking pricing in parking utilization, but they strongly oppose deregulation of minimum parking requirements. Additional outreach efforts are needed to engage local planners in parking requirement reform, to better understand the technical, policy, and political issues affecting current requirements.


Motor proteins are a vital contributor to life, where they manifest themselves in the directed movement of organisms, in cell division, and in the transport of organelles, proteins, and nucleic acids. The "Big Three" superfamilies of linear motor proteins consist of myosin, kinesin, and dynein, which move along actin or microtubules. Over the past 60 y, since the discovery of the sliding filament model for muscle contraction and the identification of myosin as the active component, considerable effort has been devoted to understanding the molecular properties of the motor domains that generate directed movement. In contrast, considerably less is known about the structural interactions of these motors with their partners, which is ironic because motors only exist to move or apply force to something! Not surprisingly, this is a rich area for investigation that is now yielding an understanding of not only the structural themes but also the regulation of motors by their cargoes. An example of this is seen in PNAS, where Shi et al. (1) reveal how the budding yeast myosin Myo4p, a class V myosin, interacts with its partners She3p and She2p to facilitate transport of mRNA. The report by Shi et al. provides structural insight into how cargo binding efficiently regulates this myosin through oligomerization rather than through a disruption of a direct head-tail inhibitory interaction as often seen in many myosins (2) and members of the kinesin superfamily (3, 4).


Porphyrins can be substituted easily and in high yield at the meso positions by using organolithium reagents. When S4-symmetric porphyrins such as 2,3,7,8,12,13,17,18-octaethylporphyrins are used as starting materials, it is possible to perform four such substitution reactions in sequence, resulting in the formation of nona-, deca-, undeca-, and dodecasubstituted porphyrins. Introduction of the first and second meso substituents can be achieved in almost quantitative yields, while the third and fourth meso substitutions proceed in about 50−70% yield with the remainder of the starting material being converted into stable porphomethenes. When one meso substituent is already present, introduction of the second residue proceeds with regiochemical preference for the 5,10-orientation over the 5,15-orientation, permitting a directed synthesis of 5,10-disubstituted porphyrins. Direct oxidation of the Meisenheimer-type intermediate formed after addition of RLi permits the introduction of two meso substituents in a one-pot reaction, again with preferential formation of the 5,10-disubstituted product. Using BuLi and PhLi as representative alkyl and aryllithium reagents, general reaction sequences were developed. These allow the preparation of meso-substituted octaethylporphyrins with almost any desired regiochemical combination of alkyl and aryl substituents. The synthesis of asymmetric, chiral, dodecasubstituted porphyrins can now be achieved in 4 to 6 steps, with overall yields in the range of 20−30%. X-ray crystallographic studies of the reaction products provided the means for the first analysis of the conformational effects of different types and arrangements of meso substituents present in one molecule. The results indicate that, depending on substituent type and localization, a mixing of distortion modes occurs. This offers significant opportunities for modulating the conformation, and thus the physicochemical properties, of these macrocycles and provides for the targeted design of biomimetic and potentially catalytically active porphyrins with specific conformations and binding cavities.


We present Kaniʻāina, the first online repository of spoken L1 ʻŌlelo Hawaiʻi. Kani'āina will allow interactive access to recordings and transcripts through Ulukau, a bilingual digital library interface that is arguably the most-accessed site for Hawaiian language materials. Kaniʻāina will also implement a procedure for crowdsourced transcription of recordings. (session 3.6.1)


It is indicated on previous examples that the study of deep-seated structures using the gravimetrie method can achieve success. Maps of parts of Inner Mongolia and northeast China showing the depths to the Moho are given in the paper. An analysis results in the following conlcusions: (1) Uplifts of the upper mantle correspond to oil-gas fields and chromium and nickel ore districts. (2) Troughs of the upper mantle are areas of distribution of skarn and hydrothermal endogenic ore deposits. (3) Zones of sharp change in the Moho can contain hydrothermal (major) and porphyry-type (minor) ore deposits. They are more favourable for ore formation when they are distorted by differently trending deep-seated fractures. Such zones are promising areas for exploration.


Abstract : There are thousands of people working on reconstruction efforts across Iraq. More specifically, 35 of those people comprise the U.S. Army Corps of Engineers (USACE), Gulf Region Division (GRD), Logistics Movement Coordination Center (LMCC), located in the International Zone. The LMCC coordinates the movement of coalition property throughout Iraq. Without the materiel moved by the LMCC, very little would be possible in the areas of security and reconstruction. "The LMCC is a collection of minds, banded together to solve the problem of movement and all its complexities," explained Jack Holly, GRD Logistics Director. "Everything you see in the LMCC are tools to assist in that decision-making process." After 2 1/2 years, the LMCC is a well-oiled machine when it comes to materiel movement. It's been accomplished with more than a little bit of adjustment to the machine along the way. From the beginning, the LMCC has been organized as a team that will one day be taken over by Iraqis. This envisioned end state created a couple of challenges from the onset. First, even though the convoy environment is extremely dangerous, the LMCC could not be a classified organization if it was to support Iraqi apprenticeship. Second, although the movement environment is military, the LMCC had to be composed mainly of contractors because the LMCC must be sustainable for reconstruction needs while coalition forces concentrate on security missions. Holly, who has been directing the LMCC since its inception in 2003, tackled these challenges by creating a new business model: a team primarily run by contractors in a military environment with a desired end state of total takeover by the Iraqi government. The LMCC was accomplished through what members of Holly's team describe as the three Cs: coordination, communication, and cooperation.


Background: The number of AIDS patients is increasing worldwide including Iran. Patients' risky behaviors play an important role in this arising trend. Assessing the perception and behaviors may facilitate for clarifying and planning to reduce the incidence of the risky behaviors. This study aimed to investigate the perception and the behaviors of the HIV/AIDS patients.   Methods: This qualitative study conducted in Counseling Behavior Center of Imam Khomeini Hospital for ten months .Data were obtained from an in-depth, semi-structured interview with an open - ended questionnaire applying purposeful sampling method. All interviews recorded and typed precisely  word by word and transcripts reviewed and checked again. Deducted themes from data coded and categorized. Results: 45 out of 61 participants were HIV positive and 16 were AIDS patients. The age range was 21-24 years and 37.7% were female. Themes described in two sections: the first was perception section, which was about ways of  acquiring  the disease; and insufficient knowledge about the transmission and prevention of the disease. The second section assessed behaviors, which  included  a number of  high-risk behaviors, non-self-disclosure of disease and not using preventive methods.      Conclusion: We concluded that more instructions or counseling in the field of transmission and disclosure of the disease is necessary to improve the social support.  AIDS instruction focusing on religious beliefs applying health behavioral change theories and endemic models of health education for supporting the community is recommended.


A mouse liver 5-30 system was used to study the early effects of dimethylnitrosammne (DMNA) on polypeptide chain initiation and messengerRNA content. The inhibition of protein synthesisafter DMNAadministration was associated with a reduced capacity of the 5-30 system to form 805 ribosomal initiation complexes. The binding of for mylatable methionyl transfer RNA to polysomes was also de pressed. The initiation defect was detectable in the assay system slightly later than the decrease in protein synthesis. Addition of mRNAstimulated both translation and 80S initiation complex formation but could not fully restore the activity of the 5-30 system from DMNA-treated mice. A loss of poIy(A)@ RNAfrom the postmicrosomalsubfraction of the 5-30 fraction was observed as early as i 5 mm after DMNA administration. Later, polyriboadenylic acid also de creased in the microsomalfraction. Monosomes accumulating in response to DMNA treatment were deficient in mRNAas measuredby polyriboadenylic acid analysis. Conversely, the proportion of polyriboadenylic acid in the remaining polysomes increased, indicating that the mRNAhad become less densely occupied with ribosomes.


An unprecedented chiral secondary amine-catalyzed formal [4 + 2] annulation of aldehydes and oxidation-generated β-unsubstituted o-QMs is reported. This asymmetric protocol allows direct functionalization of the benzylic C-H bonds and furnishes [4 + 2] cycloadducts, chromanols, with excellent enantioselectivity and in up to 92% yield. The usability of this approach was further demonstrated by the enantioselective synthesis of anticancer Rhinacanthins derivative NKPLS8.


In this paper, we are concerned with the existence of the least energy sign-changing solutions for the following fractional Schr\"{o}dinger-Poisson system: \begin{align*} \left\{ \begin{aligned}&(-\Delta)^{s} u+V(x)u+\lambda\phi(x)u=f(x, u),\quad&\text{in}\, \ \mathbb{R}^{3},\\&(-\Delta)^{t}\phi=u^{2},&\text{in}\,\ \mathbb{R}^{3}, \end{aligned} \right. \end{align*} where $\lambda\in \mathbb{R}^{+}$ is a parameter, $s, t\in (0, 1)$ and $4s+2t>3$, $(-\Delta)^{s}$ stands for the fractional Laplacian. By constraint variational method and quantitative deformation lemma, we prove that the above problem has one least energy sign-changing solution. Moreover, for any $\lambda>0$, we show that the energy of the least energy sign-changing solutions is strictly larger than two times the ground state energy. Finally, we consider $\lambda$ as a parameter and study the convergence property of the least energy sign-changing solutions as $\lambda\searrow 0$.


American Burn Association (ABA) members and guests, I am honored to have been your president for the past year. However, I stand before you by the goodwill of many who have worked with me over the years. I start with the ABA central office. Under the leadership of John Krichbaum, JD, the central office staff exhibits the same dedication to issues related to burn care, education, and research that our burn teams and we do. We owe them significant gratitude for all that they do for us for our burn centers and for our patients. I want to highlight Dan Crane, JD, PhD, and Lucie Gikovich, our lobbyists in DC. Together, they have opened doors and advanced our advocacy efforts in ways that we never could have done alone. I show a picture of this year's ABA board of trustees, (Figure 1), but of course it changes slightly every year, and each year has brought new opportunities for collaboration and friendship. Being part of the ABA has introduced me to remarkable people that I never would have known had I not joined committees. I never would have met B.J. Bartleson, Kathe Conlan, Cindy Reichart, Joan Weber, and many others from whom I have learned so much. Running a burn center requires partnership with Administration, and I have been fortunate to have outstanding department and hospital leaders, including Dr. Ronald V. Maier, Dr. Carlos A. Pellegrini, and Johnese Spisso, RN BSN, MHA, who have allowed me to personally grow and build the burn center for the past 10 years. As ideal administrators, they supported me when I needed help, but left me alone otherwise. I could never do what I do every day without the help of my remarkable burn team. These people make things happen at the bedside daily. Every time we set a challenge for improving patient care or meeting hospital benchmarks, I can count on the burn team under our tireless management to meet that goal. Thank you for all the years of striving for excellence in all we do. I am very proud to be part of your team. I also need to acknowledge my research lab. They don't allow me at the bench anymore, but I always trust them to work with precision. I could never have maintained my laboratory without the efforts of many students, fellows, research coordinators, and collaborators. Never give up an opportunity to toast a colleague. It is important to have colleagues whom you respect and trust—it is best to be able to call them friends. Drs Matthew Klein and Tam Pham have grown from fellows to mentees to colleagues. One colleague who has been at my side for 22 years, Shari Honari, RN BSN, has humbly overseen our clinical research program and kept us out of regulatory trouble by assuring that every t is crossed and every i is dotted. She has also cared for me, fed, and quietly advised me on how I could do things better—whether by controlling my temper or being more fastidious in the operating room. Everyone needs good mentors. I highlight Dr. Erwin F. Hirsch, an early member of the ABA with an interest in radiation burns, who was my fiercest advocate throughout my training and probably was the surgeon who taught me to suffer no fools. As intimidating as he could be, his insistence on excellence and quality of care for the trauma patient was inspiring. From early in my academic career, I have marveled at Ron Tompkins' clearheaded ability to separate the wheat from the chaff and home into relevant scientific and bureaucratic issues. I still remember our first interaction at a particularly rancorous National Institutes of Health (NIH) Program Project site visit when he adeptly navigated us away from the politics and kept the reviewers focused on the science. I am grateful for David Herndon's counsel early in my days as an NIH reviewer when I was witness to his staunch advocacy for young investigators—especially young surgeons. When Dr. Richard Gamelli speaks, From the Department of Surgery and Regional Burn Center, University of Washington Medicine, Harborview Medical Center, Seattle, Washington. Presented at the 44th Annual Meeting of the American Burn Association Seattle, WA, April 24, 2012. Address correspondence to Nicole S. Gibran, MD,FACS, Harborview Medical Center, Box 359796, 325 Ninth Avenue, Seattle, Washington 98104. Copyright © 2013 by the American Burn Association. 1559-047X/2013


These tests were performed to compare different timings and combinations to give season-long control of PP on pears. Treatments were applied to plots that were 3 rows wide by 3 trees long replicated four times in a RCB design. Treatments were applied with an air-blast sprayer calibrated to deliver 200 gpa on prebloom applications and 100 gpa on postbloom applications. The outer rows of each plot were sprayed inward only to control overspray to adjacent plots. The middle row was sprayed from both sides to give good overall spray coverage. The Raynox treatments were applied to single-tree plots replicated four times using a handgun sprayer at 200 gpa. All insect counts were made on the middle tree of the middle row of each plot or, in the case of the Raynox treatments, on each of the treated trees. The conventional prebloom treatments were followed either by conventional postbloom sprays or applications of either Raynox or Surround. Conventional postbloom treatments were preceded by conventional prebloom treatments, or prebloom applications of either Raynox or Surround. PP adult counts were made by using a beating tray and counting the number of adults on four trays. PP egg and nymph counts through 19 Apr were made by collecting 5 spurs per plot, examining them under magnification, and counting the number of eggs and nymphs. On 28 Apr, 25 leaves were collected from each plot and brushed with a standard mite-brushing machine onto a glass plate. Plates were examined under magnification and the number of egg and nymphs counted and recorded.


A new class of surface damping treatment is proposed to provide effective means for attenuating undesirable structural vibrations. The proposed treatment relies in its operation on the use of smart damping treatments which consist of integrated arrays of constrained visco-elastic damping layers that are controlled passively by a specially arranged network of permanent magnets. The interaction between the magnets and the visco-elastic layers aims at enhancing the energy dissipation characteristics of the damping treatments. In this manner, it would be possible to manufacture structures that are light in weight which are also capable of meeting strict constraints on structural vibration when subjected to unavoidable disturbances. Emphasis is placed here on introducing the concept and the basic performance characteristics of this new class of smart Magnetic Constrained Layer Damping (MCLD) treatments. Comparisons are also presented with conventional Passive Constrained Layer Damping (PCLD) in order to determine the merits and limitation of the MCLD treatments.


Like many cities throughout the UK, Glasgow has a long history of both
urbanisation and industrialisation, resulting in elevated concentrations of potentially
harmful elements (PHEs). Between 1830 and 1968 Glasgow was home to one of the
world's largest producers of Cr-based chemicals. Chromite ore processing residue
(COPR) arising from the factory was used as infill material across large areas of SE
Glasgow, resulting in widespread land contamination with Cr(VI), a known human
carcinogen of significant mobility. A recent survey by the British Geological Survey
(BGS) of Glasgow and its surrounding urban environment has highlighted numerous
sites with total Cr concentrations exceeding soil guideline values (SGVs) generated by
the Contaminated Land Exposure Assessment (CLEA) model.


Neuronal simulations fall in two broad classes: ones that use spiking neurons and ones that don't. While spiking models match biology better than rate-based systems, computationally they can be quite expensive. The literature offers some attempts to find and use rate-based neuron models that capture important properties of spiking units. One of the most rigorous approaches [1] approximates the output rate of leaky integrate-and-fire neurons (LIF) for Poisson input trains by analyzing the subthreshold activity of the neuron [2]. This approach, the Siegert neuron, is shown in Fig. 1.


This article presents additional vocational training institutions' experience in the development of supplementary educational programs (advanced training) with account of the Federal Law "On Education in the Russian Federation" requirements. The article contains methodological approaches to formation and realization of supplementary professional programs in healthcare.


Moral rationalism has accustomed us to understand the past in terms of personal reasons for acting. In this sense, it is said human action is rational because it can account for their motives. This principle, extrapolated into the future, understands existential projects as deliberative planning. The phenomenology of action and corporality set out a more complex problem on the relationship between a plan and its implementation, having into account physical and intersubjective conditions of projects, as well as its elusive face when pursuing a merely conceptual articulation of them. This paper aims to develop a phenomenology of these tensions between any project and its execution in two sections: (a) the existence as a project, and (b) such an existence and the structured project: the limits of discourse.


Since middle term of 1990s,domestic academic circle makes thorough research on the construction of Chinese soviet republic in terms of politics,economics and law,obtaining great achievements.There still exists major difference on some basic problems for evaluating historical position of Chinese soviet republic.The summary on the study will be the theoretic source for further wide research.


The practical range of economic fluctuation,also acceptable growth rate of fluctuations,is made up of ceiling and bottom limits.The difficulty to define practical range is to define numerically the ceiling and bottom limits.The article used systematization,of majority principle,least principle,middle principle,average principle,to define the practicable range of Hunan economic fluctuation:ceiling is12% and bottom limit is 5.5%.Finally,the article put forward advice on how to keep Hunan economy in practical range.


The properties of nanometer-thin pure boron layers deposited by chemical vapor deposition were investigated for use as a barrier against tetramethyl ammonium hydroxide (TMAH) and potassium hydroxide (KOH) etching of Si. Deposition temperatures of 400 °C and 700 °C were applied to form layers of a few nanometer thick. Down to 2-nm thickness, they were all found to be resistant to these wet Si etchants. Patterning of the layers was achieved with resist masking and standard aluminum wet-etchant. The selectivity to Si was extremely high, much greater than 104. Cavities <inline-formula> <tex-math notation="LaTeX">$70~\mu \text{m}$ </tex-math></inline-formula> deep were etched without measurable etching of the boron layers, and with <inline-formula> <tex-math notation="LaTeX">$\langle 100\rangle /\langle 111\rangle $ </tex-math></inline-formula> etch-rate ratios of about 35 for TMAH and larger than 50 for KOH. Stress levels were measured to be 490 MPa tensile for 400 °C and 1250 MPa compressive for 700 °C deposition. Hundreds of micron wide membranes that remained intact were fabricated. [2017-0175]


A refastenable disposable garment defining a longitudinal and transverse direction and comprising a first waist region connected to the first waist edge. The first waist region defines a first surface and a second transverse spaced apart first and second sides and defining an. The first waist region in the vicinity of the first and second sides is elastomeric. The garment may comprise a first and a second waist region and second waist regions a crotch region interconnecting. The garment comprises in the vicinity of each first and second sides attached to a first surface of the non-extensible first waist region, the relatively rigid first and second fastener. The first waist region, respectively, defining a first transverse direction and the first and second flange portions outside the second fastener. Each flange portion to the second surface of the transverse curl. Also disclosed is a method for manufacturing such articles.


To provide the basis for comprehensive utilization and development of palm,the content and antioxidant activity of total flavonoids from palm fruit were determined by spectrophotometry and DPPH method.Results:The total flavonoids content of palm fruit was 1 728.15μg/g.The free radical scavenging rate was 69.98% when the total flavonoids extract concentration was 772μg/mL,The oil antioxidant POV achieved 0.052 when the total flavonoids extract concentration was 0.505 8μg/mL.


We consider a method, which permits to harness the classic linear-quadratic optimal control theory for solution of certain specific nonconvex problems of global multicriteria constrained optimization. This method enables one to find the set of all the Slater optimal solutions and consists in a certain combination of the weighted average method and the method of Lagrange duality. New criteria for the above method to be applicable are established. The theory developed is illustrated by examples concerning diverse optimal control problems.


BACKGROUND: The aim of this study was to identify the parents' experience of moral education to their children in secondary school and with a phenomenological method. MATERIALS AND METHODS: Participants include parents of students who received a high score after taking Dr. Lotfabadi's moral development test and extracting the results. The students' parents consciously and satisfactorily participated in the semi-structured interviews prepared for this purpose, and the interviews continued until the saturation stage, so the final sample size was 22 participants. The data obtained from the interview were then analyzed using the Van Menen method to discover the meaning of the students "parents" experiences of moral education. RESULTS: Findings were revealed in 5 main themes of social ethics, family ethics, individual ethics, self-care ethics, and environmental ethics and 15 sub-themes. CONCLUSION: According to the findings of this study, it seems that parents to pay more attention to the components of social ethics, family ethics, individual-human ethics, self-care ethics, environmental ethics to succeed in raising children with desirable moral development pay special attention to these components to raise worthy children with desirable moral development.


We investigate parameter synthesis in the context of temporal-epistemic logic. We introduce CTLPK, a parametric extension to the branching time temporal-epistemic logic CTLK with free variables representing groups of agents. We give algorithms for automatically synthesising the groups of agents that make a given parametric formula satisfied. We discuss an implementation of the technique on top of the open-source model checker mcmas and demonstrate its attractiveness by reporting the experimental results obtained.


In this thesis three separate problems relevant to general relativity are considered. Methods for algorithmically producing all the solutions of isotropic fluid spheres have been developed over the last five years. A different and somewhat simpler algorithm is discussed here, as well as algorithms for anisotropic fluid spheres. The second and third problems are somewhat more speculative in nature and address the nature of black hole entropy. Specifically, the second problem looks at the genericity of the so-called quasinormal mode conjecture introduced by Hod, while the third problem looks at the near-horizon structure of a black hole in hope of gaining an understanding of why so many different approaches yield the same entropy. A method of finding the asymptotic QNM structure is found based on the Born series, and serious problems for the QNM conjecture are discussed. The work in this thesis does not completely discount the possibility that the QNM conjecture is true. New results released weeks before this thesis was finished showed that the QNM conjecture was flawed. Finally, the near-horizon structure of a black hole is found to be very restricted, adding credence to the ideas put forward by Carlip and Solodukhin that the black hole entropy is related to an inherited symmetry from the classical theory.


Referring to critical matrix-thickness mechanism proposed by Wu Sou-heng,taking montmorillonite layer as a unit and assuming the stress-affected area as spherical,a percolation model of polymer-montmorillonite exfoliative nanocomposites(PLSN) was developed.The threshold of PLSN percolation obtained hence is 0.52,which is independent on the distribution of the content,properties and particles size of polymer and montmorillonite.Besides,the toughening mechanism of polymer-montmorillonite exfoliative nanocomposites was theoretically analyzed with percolation theory.And the toughening behavior of exfoliative epoxy-STAB-montmorillonite nanocomposites was also evaluated with percolation theory and found that the scale is 0.19.Which shows that exfoliative montmorillonite layers become cross-linking of nanocomposites and own toughening effection.The behavior of toughening corresponds with percolation theory.


The central question to be addressed before starting to design any music application is how to represent music internally. My paper revisits the basics and looks systematically and
thoroughly, albeit reflectively and philosophically, at music representation schemes outside the digital world: music notations in the pre-computer age. Following on from there, I ask how much of their functionality is actually supported at present. I see this as part of a search for the "holy grail in music technology", the ultimate design for music data representation (if such a thing exists). Like all other grail-hunters, this academic simply cannot stop believing in its existence. To our critics, the followers of the "not-another-standard" camp, we grail-hunters tend to maintain that the journey is part of a process – a journey towards some sort of (musictechnological) enlightenment. My work has, therefore, involved looking at the methodologies used for designing systems and data structures. This paper is part of this work and looks specifically at issues around notation, control and the resulting requirements for digital representation.


Introduction: Fibrous histiocytoma is the name for a group of lesions characterized by biphasic cell populations of fibroblast and histiocytes. both benign and malignant forms have been described. the benign form often shows relapse following treatment and shows poor response to chemotherapy and radiotherapy. therefore, radical excision or resection remains the therapeutic goal. case report: Herein, we present a case of recurrent benign fibrous histiocytoma of the head and neck in a 25-year-old Nigerian male that was excised and skin grafted. conclusion: Fibrous histiocytoma is less common in the head and neck region.


Tangshan is not only a strong economic city but also a high energy consumption city in Hebei province. Although Tangshan GDP occupies 1/5 of the provincial total, the energy consumption accounts for 1/3 of the provincial total. Facing the challenge of the low carbon economy, urban environmental problem has already become the bottleneck of future development in Tangshan, which directly influences the competition ability of this city. This paper expounded the general situation of Tangshan, and analyzed the influences of its economic development on urban environment. From strengthening low carbon awareness, planning urban construction with low carbon concept, and developing low carbon industry clusters, constructs Tangshan city marketing strategy system, thus promote Urban Competitiveness of Tangshan City.


The emerging field of "data mining" is (according to Pregibon (1996)) a blend ofstatistics, artificial intelligence, and database research. It is projected to be a multibilliondollar industry by the year 2000. I propose the name "statistical methodsmining" for the process of developing (and marketing) various maps of the world ofstatistical knowledge in order to apply to data mining the enormous virtual encyclopediaof statistical knowledge that exists in the literature. I propose that planning moderncore, applied, and computational statistical activities should be based on statistical historywhose mottos are \the purpose of statistical computing is insight not numbers"and \the purpose of statistical history is insight (about future influences) not details (ofpast influences)". The goal of statistical methods mining is to promote the optimumpractice of analysis of diverse (possibly massive) data sets by enabling researchers inall fields to be made aware that statisticians have important roles to play to provideexpertise about classical and modern statistical methods, theory, practice, applications,and computational techniques for data mining and statistical inference (extraction ofinformation and identification of models from data). Contents of this paper are: 1.Future of statistics is bright, future of statisticians needs planning; 2. W1hat wentwrong in the recent history of statistical science; 3. Balancing core research and interdisciplinaryresearch; 4. Statistical education and statistical modeling are analogousiterative cycles; 5. Statistical history was never neglected in past thinking about thefuture of statistics.


T IS OFTEN difficult to determine the site of I origin of adenocarcinomas involving the endocervical and endometrial mucosa. This distinction is important in view of the differences in therapy employed in the treatment of the tumors. Both endocervical and endometrial cells are capable of secreting mucin. In many instances, the glandular lumina of normal mucosa and tumors originating from these cells contain an amorphous mucoid material. Based upon the premise that a tumor may retain in whole or in part the function of its cells of origin, the mucins of endocervical and endometrial mucosa were investigated. Differences between the intracellular mucins of normal endocervical and endometrial mucosa and those of adenocarcinomas arising from these areas are described.


Technology scaling has been the workhorse of semiconductor industry for over three decades for achieving the goal of smaller, faster and cheaper ICs. But continuous scaling has led to decrease in feature sizes to such levels that the fundamental physical limits of materials have become a bottleneck for further miniaturization in the Ultra Deep Sub Micron regime. These limitations have posed a challenge in the form of short channel effects, off-state leakage current, gate leakage current, decrease in carrier mobility and on-state current, polysilicon depletion region and the effects of random dopant fluctuations. To counter these limitations, specific solutions have been critically examined and presented. These solutions mark the beginning of non-classical scaling era and include usage of strained silicon, high-k dielectrics, metal gate electrodes, exploration of other semiconductor materials and crystal orientations. Novel device architectures like Double Gate MOS, FinFET, MuGFET and Ultra Thin Body-Silicon on Insulator MOS are examined for their potential to keep Moore's law alive for the next decade.


The aim of the study was to determine whether collagen‐polyvinylpyrrolidone (collagen‐PVP) modifies some proinflammatory responses in synovium cultures from rheumatoid arthritis (RA) patients. Synovium from 10 RA patients were cultured with or without 1% collagen‐PVP. Tissues on the 3rd, 5th and 7th culture day were sectioned and stained by the Herovici technique. Total collagen and type I/III collagen ratios were evaluated by the Woessner micromethod and by interrupted gel electrophoresis, respectively. Collagenolytic activity was assessed by degradation of [3H]‐collagen in supernatants. TIMP‐1, IL‐1β and TNF‐α were determined in supernatants by ELISA, and the results were normalized by DNA concentration. IL‐1β, TNF‐α, IL‐6, IL‐8, MMP‐1, TIMP‐1, Cox‐1, VCAM‐1, ICAM‐1 and Fas/APO95 expression was evaluated by immunohistochemistry. Apoptosis was detected by TUNEL technique. The histological analysis and electrophoresis revealed a 1·7‐fold increase of type III collagen in a time‐dependent fashion in collagen‐PVP‐treated cultures. Proinflammatory cytokines (IL‐1β: 58 ± 9 versus 22 ± 10; TNF‐α: 41 ± 6 versus 11 ± 3; IL‐8: 59 ± 12 versus 29 ± 9; treated versus untreated), adhesion molecule (ICAM‐1: 57 ± 11 versus 29 ± 15; VCAM‐1: 49 ± 7 versus 21 ± 13; treated versus untreated) as well as Cox‐1 (59 ± 10 versus 20 ± 3) expression was down‐regulated in RA synovium treated. Meanwhile, TIMP‐1 (36 ± 7 versus 57 ± 11) and Fas expression (20 ± 10 versus 55 ± 13) and apoptosis (14 ± 3 versus 55 ± 5) were up‐regulated in treated cultures compared with controls. In supernatants, the collagenolytic activity, as well as IL‐1β and TNF‐α, levels were all down‐regulated in treated cultures (two, three, fourfold, respectively). The addition of collagen‐PVP to synovium‐induced down‐modulation of some inflammatory parameters and an increase in apoptosis of synovial cells. Perhaps this mechanism could contribute to inhibit outgrowth of pannus formation and to down‐regulate inflammation of joints in patients with RA.


The primary inspection of composite structures is usually performed on composite components prior to assembly into a full structure. Inspection of these structures after assembly verifies the quality of the structure before it is placed in service, and can provide a baseline for future in- service inspections. This paper addresses the concerns, problems, and solutions that have been addressed for post-assembly inspections at McDonnell Douglas.


Larvae free number (LFN) is a measure to evaluate the prevention of dengue
hemorrhagic fever (DHF) through environmental management. It was assumed that the
greater the LFN, the smaller the potential for transmission and vice versa. This study
aims to prove whether LFN associated with incidence of DHF. This was an observational
study using retrospective method. The study was conducted in 17 villages of 4 subdistricts
in Sleman, Yogyakarta with different levels of endemicity. Larvae free number
and the incidence of DHF from year 2009 to 2013 used as independent and dependent
variable respectively. Data of LFN and incidence of DHF obtained from District Health
Of ce. There were 1,461 DHF cases in 4 sub-districts in year 2009-2013. The average
of LFN was 80.70 (68.4-95). The relationship between the LFN and DHF were analyzed
by Pearson Correlation. This correlation test showed that the LFN was not associated
with the incidence of DHF (p = 0.312). It is concluded that the value of LFN is not
correlated with the incidence of DHF in Sleman, Yogyakarta.


The cerium(III) chloride heptahydrate/sodium iodide complex (CeCl 3 . 7 H 2 O/NaI) acts as a useful promoter in the carbon-carbon bond forming reaction by addition of allyltributylstannanes to aldehydes. The reaction of 2-butenyltributylstannane shows that the regio- and the stereochemical outcomes depend on the reaction conditions. When the promoter is adsorbed on a solid support (aluminum oxide), a highly prevalent formation of the γ-adduct is observed in solvent-free conditions. Conversely, when the reaction is carried out in acetonitrile as the solvent, the α-adduct largely prevails. In the last case, a complete stereocontrol is observed, the less stable (Z)-isomer being obtained in high geometrical purity.


This study extended the work of White and Dunlap (1999) by quantifying faculty views regarding the relative effects performance and effort should have on final grades and by comparing faculty views with student views to assess their similarity. Survey results of 159 students and 59 faculty indicated that students believed effort should influence grades significantly more than did faculty. Differences existed when measuring performance and effort as (a) a percentage of a final course grade and (b) letter grades assigned in different course types. In addition, faculty and students differed significantly in the number of hours they designated as defining superior effort. Discussion of results considers the potential impact discrepancies can have on faculty and student relations, student learning, and student evaluation of teaching.


The paper first limits the scope of the Connected Belt of Urban-Rural,gives the thoughts of Ecological Optimization of Land Use Structure;Then with Cangshan Region of Fuzhou City as an example,from the land use structure present situation and the existence question,analysis the land use structure change in 1989?1996?2003 and 2010.In the end,applying the principles of ecology,from economic,social and ecological benefits and so on multi-objective,discusses the measures to the Cangshan Region and establishes the normal model of ecological optimization of land use structure and the practice significance of application.


Understanding and minimizing risks associated with travel are important components of the management of patients with inflammatory bowel disease (IBD). IBD patients are often young and commonly travel widely. However, many feel their disease limits their ability to travel with concerns regarding infection, disease flare, and access to healthcare abroad. A retrospective study of 222 patients with IBD and 224 healthy controls found that while patients with IBD were prone to illness during travel, this was primarily driven by travel to industrialized countries, suggesting most travel-associated illnesses stem from sporadic IBD flares rather than increased susceptibility to enteric infections. On multivariate analysis, the strongest risk factors for illness during travel for patients with IBD were number of flares, prior hospitalization, and remission status for more than 3 months preceding travel. Therefore, it is important to optimize IBD control prior to travel and where possible have patients in sustained remission to minimize risk of disease flare, hospitalization, or complications such as venous thromboembolism (VTE). Ideally, plenty of time should be provided to appropriately plan for any significant patient travel. This includes ensuring patients are up to date with all relevant vaccinations, with special consideration needed for live vaccines such as the yellow fever vaccine, which cannot be given to patients on immunosuppressant medication. Patients on immunosuppressant medication, including immunomodulators and anti-TNF agents, need to be vaccinated four to 6 weeks before starting an immunosuppressant or 3 months after stopping it. Therefore, patients currently receiving immunosuppressant treatment are required to discontinue therapy for 4 months in order to be vaccinated. It is thus important to ask patients newly diagnosed with IBD about future travel plans and consider pre-emptive yellow fever vaccination which confers lifelong immunity. Patients need to ensure they take enough supply of their regular IBD medications for their trip plus any unforeseen delays. Additional logistical planning is required for those on biologic treatment including travel packs and needle disposal for injections. Adalimumab and ustekinumab must be kept cool, preferably in a cool bag with ice packs until they can be stored in a refrigerator. Biologic infusion scheduling at the travel destination needs to be coordinated early at an appropriate facility to avoid dose interruption or delay. Patients should also have an action plan in case of IBD flare or gastrointestinal infection while overseas and take emergency medications as appropriate such as prednisone, enemas, and antibiotics for traveler's diarrhea. Patients with IBD are at increased risk of VTE compared to the general population, with long-haul airline travel being an independent risk factor. Patients with IBD should adhere to general VTE prevention advice when flying including wearing loose clothing, staying well hydrated and avoiding excess alcohol, calf exercises and frequent mobilization, and consideration should be given to wearing correctly fitted compression stockings. There are no data on the role of pharmacologic prophylaxis for prevention of travel-associated VTE in patients with IBD. Limited data from small or retrospective studies provide insufficient evidence to support routine pharmacologic prophylaxis for extended travel in the at-risk population of travelers. Medical prophylaxis (such as with enoxaparin 40 mg subcutaneous or rivaroxaban 10 mg oral) can be considered on a case by case basis in high-risk patients including those with prior VTE, active disease, and long-haul international flights. However, a recent global survey of gastroenterologist travel advice to patients with IBD found a lack of consensus on the role of medical VTE prophylaxis. Patients with IBD should also adhere to general and destination specific travel advice regarding infection risk control. Depending on the destination, careful food hygiene (avoiding street stalls, salads, peeled fruits, raw or uncooked meat, ice; use of bottled or boiled water) may be required. For destination specific travel advice, especially with respect to infections associated with travel to tropical or developing countries, a formal travel clinic appointment may be warranted. Managing tuberculosis (TB) risk is a commonly encountered problem faced by IBD patients on immunosuppressants who travel to TB-endemic areas. While there are limited data to guide physicians, a recent survey of gastroenterologists found that they were more likely to advise patients not to travel to TB-endemic areas if on both an anti-TNF and azathioprine, than if on vedolizumab and azathioprine [47% vs 17.6%, P < 0.01]. Despite this, two-thirds of gastroenterologists would still continue all IBD treatments and not cease any medications if their patient chose to travel to a TB-endemic area. When patients with IBD travel to TB-endemic areas, they should be advised to avoid large crowds or sick contacts and use an N95 face mask if high-risk exposure is anticipated. There is no role for TB prophylaxis, but it is reasonable to re-check the QuantiFERON-TB Gold status post travel. There are many useful government and professional body resources that patients with IBD can refer to for additional guidance with respect to travel. There are also international resources to help inform and connect patients with specialized IBD centers at their destination. Patients should ensure they have comprehensive travel insurance that covers pre-existing illnesses and hospitalization. With appropriate planning, a diagnosis of IBD should generally not limit the ability of affected patients to travel. doi:10.1111/jgh.15460


Motor vehicle crashes (MVCs) have a huge cost to society in terms of death, injury and property damage. The cost of fatal MVCs alone is estimated at US $44 billion per year. Among many confounding factors, traffic citations as an element that may reduce MVC frequency are not well understood, and most research carried out to date has evaluated the effects of the total number of citations on the number of MVCs. However, certain types of citations may be more likely to reduce the number of MVCs, whereas other types are not very effective. This research was set out to examine the impact of different types of traffic citations on MVCs on two hazardous main US highways in Wyoming US-30 and US-26. A negative binomial modeling technique was implemented by exploiting 4 years of crash and citations data to identify the causal impacts of traffic citations on crash frequency by incorporating traffic and geometric features. The modeling results showed that higher numbers of speeding and seat belt citations reduce the number of crashes significantly. These findings are the results of law enforcement efforts along the highways. Traffic count and the number of horizontal curves were found to significantly increase the number of MVCs.


This paper proposed and implemented the restructuring of a multiple video files to a single file multiple image output. First introduced the video composition principle. On this basis, elaborated the method of video reorganization, And then using Mp layer, Mencoder and Image Magick to implement the whole process, Finally, with popular streaming media file Flv as an example conducting experiments and to analyze and compare the result.


Recently the Central Statistical Administration of the USSR Council of Ministers published a number of statistical collections. The collection "Transport and Communications in the USSR" undoubtedly is interesting for the study of specific problems.


We report a case of bilateral anterior ischaemic optic neuropathy in a 23-year-old woman which was probably attributable to optic disc drusen and systemic hypotension related to peritoneal dialysis for renal failure.


In recent years, many complex high-rise buildings are under construction for the effective use of land. But the engineers could not find proper data of the standard for approximate quantity of frame work of complex high-rise building due to the less experience and relatively short history of complex high-rise building. This study is to make clear of the standard for quantity of framework by using mean value. For this study, the historical data 22 buildings 3,003 departments constructed from 2003 to 2006 is collected. Histroical data as the design quantity of reinforcing bar, form, and concrete, suggests the standard of approximate quantity as the arithmetical average for total area of complex high-rise building.


The Fe3O4 modified with chitosan was synthesized as carrier material.The glutaraldehyde was coupled with amido group of chitosan.magnetic molecularly imprinted polymer(MMIP)was prepared by surface imprinted using trypsin as the template,acrylamide as the functional monomer and cross-linker at the same time.The results showed that,compared with non magnetic molecularly imprinted polymer(NMMIP),MMIP showed higher adsorption efficiency and higher selectivity,and the maximum adsorption capacity was 162.6 mg·g-1.The experiment of adsorption and selective also showed that the magnetic imprinted polymer had Scatchard analysis showed that two different adsorption sites and their dissociation constants were 96.5 mg·mL-1 for higher affinity binding sites and 2.41 mg·mL-1 for lower affinity sites.


The project aims to study and design an alternative user interface for collaborative virtual environments (CVE's) software also known as networked virtual environments (NVE's). To reduce cost, most current and operative CVE's use the Internet and standard PC to create a visual virtual environment (VE), which can be shared by a large number of users. This project also involves an image processing technique (morphing technique using thin plate spline) for creating a facial expression for the CVE software and in volves OpenGL API for implementation. This project discusses communication aspects in the CVE system and suggests the different types of communication that are suitable for the project. It also suggests a suitable user interfaces for the software.


We have explored 3D NAND memory operation of oxide-semiconductor (OS) channel FeFETs by TCAD simulation with a multi-transistor NAND-string model. Key challenges in 3D NAND memory devices, such as (1) pass voltage disturb, (2) interference from adjacent cells, and (3) inhibit operation of unselected bitlines, are addressed. For a target device structure, operation voltages can be optimized to satisfy the requirement of (1)-(3). We have also studied the potential impact of in-plane polarization under the spacer. A comparative study shows that in-plane polarization under the spacer may lead to unexpected characteristics of OS-channel FeFETs in 3D NAND memory operation. This paper will provide insights on the feasibility of 3D NAND FeFETs for high capacity storage memory.


Autoantibody-inducing CD4 T (aiCD4 T) cell seems indispensable for the self-organized criticality theory that induces Systemic Lupus Erythematosus (SLE). We previously found that the aiCD4 T cell belongs to CD45RBlo122lo CD4 T cell subpopulation. We here analyze the B cell population and CD19+ splenic B cell receptor (BCR) repertoire, and test our contention whether aiCD4 T cell helps B cell maturation.

 BALB/c mice were immunized with OVA twelve times and SLE was induced. Cell surface markers of B cell were detected with flow cytometry. CD19+ splenic B cells were sorted and BCR repertoires of these cells were analyzed on next generation sequencer.

 After twelve times immunization of mice with OVA, follicular B (Fo B) cell and germinal center B (GC B) cell were significantly increased(P<0.05), whereas marginal zone B cell was decreased. Activation markers of the B cell were increased and in particular, CD80 was significantly increased (P<0.05). In addition, the number of clonotypes of CD19+ splenic B cells in OVA immunized mice was increased. Among these repertoires, the same pairs of V and J usage were frequently found in OVA immunized mice.

 Fo B cell and GC B cell and the activation markers of B cell, as well, were significantly increased in OVA immunized mice, and the result of BCR repertoire analysis suggested that somatic hyper mutation occurred frequently in OVA-stimulated mice, which is compatible with the contention that aiCD4 T cells helps the maturation of B cells into germinal center B cells to enhance autoantibody formation thereby inducing SLE.


A new planar microstrip Ultra-wideband antenna for multi-input-multi-output (MIMO) applications is proposed. The presented antenna has a very compact size of 15 × 13 mm 2 which is printed on a cheap substrate of FR-4. The reflection coefficient and radiation patterns of the antenna are measured and presented. Different configurations of array of the antenna for MIMO application are also studied. .


On the basis of our fluid model calculation,the Monte Carlo method is used to investigate the resonance radiation and imprison process of resonance photons.The characteristics of discharge,radiation and imprison of resonance photons are calculated for both shadow mask PDP (SMPDP) and AC coplanar PDP (ACC PDP) respectively. The temporal variance of average density and density distribution of electron and resonance Xenon are shown.The distribution and number of photons arriving at each wall of the cell is simulated.The spectrum distribution of 147nm vacuum ultraviolet for different structure is also calculated.It can be seen that the efficiency of SMPDP is larger than that of ACC PDP.


This work presents an analysis of the occurrence of software errors at ARM Cortex-A9 dual-core processor. Fault injection results compare the error rate and their causes. Results show that different parallelization algorithms can have different error rates, and that there is a tendency on parallel applications to have more silent data corruption errors than their sequential counterparts.


ABSTRACT In this paper, we put forward 'kernel Liu prediction approach' instead of 'kernel prediction approach' under multicollinearity case in partially linear mixed measurement error model. We obtain the necessary and sufficient condition for the superiority of the linear combinations of the predictors in the sense of the matrix mean square error criterion and give the selection of the Liu biasing parameter via the Conceptual Prediction ( ) criterion. The asymptotic normality condition is examined and the unknown covariance matrix of measurement errors circumstance is derived. We study a numerical example together with a Monte Carlo simulation study to evaluate the performance of the kernel Liu prediction approach at the end of this paper.


The article examines the problem of preserving the memory of a place that is especially significant in the system of public spaces of the city, as well as the change in the image of urban space in the course of its historical development.


A new heuristic approach, called Single Hoist Cyclic Scheduling Problem (SHCSP), is presented in this paper to minimize the cycle time of the single hoist scheduling problem. This heuristic is compared to a MIP model solved by Ilog-Cplex Solver. Simulation results show the efficiency of the SHCSP heuristic, where the optimal solution is reached for more than 54 instances from literature on a reasonable computational time (less than 1 second).


With the development of "Internet+", remote test and calibration of instruments has brought many new challenging problems while innovating the traditional test and calibration work mode for measurement instruments. A universal remote calibration model is proposed in this paper. Then, the overall architecture design of the remote calibration system is presented. Based on the power remote calibration model and existing services, a remote communication and calibration system between the calibration laboratory and the central laboratory is realized by the TCP/IP protocol, and the remote instruments calibration experiment is completed. Data generated by the power system calibration process (including test data, voice and video data) has different requirements in terms of reliability, security and real-time. And OPNET is adopted to verify the network real-time communication and prove the reliability and communication efficiency of the remote test and calibration system.


This paper discusses a free‐ and a forced‐vibration problem of elastically cross‐supported rectangular viscoelastic plate with various edge conditions. A three‐elements viscoelastic model is adopted in the analysis. The result for the viscoelastic plate is obtained from the correspondence principle by applying the Laplace transform to the constitutive equation for the viscoelastic materials and to the equation of motion in terms of unknown forces which are equivalent to reaction forces and resisting moments of the supports. Some numerical results are shown for steady‐state and transient response problems.


Speech and language based automatic dementia detection is of interest due to it being non-invasive, low-cost and potentially able to aid diagnosis accuracy. The collected data are mostly audio recordings of spoken language and these can be used directly for acoustic-based analysis. To extract linguistic-based information, an automatic speech recognition (ASR) system is used to generate transcriptions. However, the extraction of reliable acoustic features is difficult when the acoustic quality of the data is poor as is the case with DementiaBank, the largest opensource dataset for Alzheimer's Disease classification. In this paper, we explore how to improve the robustness of the acoustic feature extraction by using time alignment information and confidence scores from the ASR system to identify audio segments of good quality. In addition, we design rhythm-inspired features and combine them with acoustic features. By classifying the combined features with a bidirectional-LSTM attention network, the F-measure improves from 62 . 15% to 70 . 75% when only the high-quality segments are used. Finally, we apply the same approach to our previously proposed hierarchical-based network using linguistic-based features and show improvement from 74 . 37 % to 77 . 25 %. By combining the acoustic and linguistic systems, a state-of-the-art 78 . 34% F-measure is achieved on the DementiaBank task.


sition of critical evaluative skills in applying feminist theory to re® ne image construction. As an example, in tackling concerns about marginalization of women's issues in station newscasts, we could pose as a problem, What would it take to convince my colleagues that it would be in their and the station's best interest to change the focus of our news coverage? What do I need to ® nd out? How can I work cooperatively with the members of the news production team in order to begin rede® ning our focus? The problem solving, cooperative skills that would allow a student to blend feminist theory with professional production practice in coursework could also facilitate the social changes that we hope to see emerging from our feminist media studies classrooms.


If someone had predicted in 1947 that five years later the southern states would be transferring over a million dollars across state lines to help support professional schools in medicine, dentistry, veterinary medicine, and social work, he would have been called visionary or, more likely, idiotic, for there was no precedent for transfer of educational funds to anything like that extent. To be sure, West Virginia and Virginia had executed a contract in 1946 under which the Medical College of Virginia agreed to accept 20 third-year medical students upon payment of $1,000 per student per year. That program, though a beginning, was necessarily small. It could hardly foreshadow the organization of the Southern Regional Education Board, under a 14-state compact, which now guides a program affecting 850 students, 19 public and private universities, and 14 states. The board itself brings together educational and political leaders to help institutions plan programs


The present invention discloses a production method of flavoring dried fresh fish. Said method includes the following steps: killing fresh fish, eviscerating, washing, pickling, draining, spreading, baking and cooling, in which the pickling step adopts the flavoring material formed from 2-3 portions of edible salt, 1-2 portions of white granulated sugar, 1-2 portions of garlic, 0.5-1.5 portions of mononatrium glutamate, 0.5-1.5 portions of yellow wine, 0.5-1.5 portions of white liquor, 0.5-1.5 portions of fresh ginger, 0.15-0.25 portion of dried hotpepper, 0.05-0.15 portion of star anise and 0.05-0.15 portion of xanthoxylum to pickle 100 portions of fresh fish body for 3-6 hr. at 0-10dec.C.


Under the auspices of the Ciba Foundation 28 leading scientists met in London in July, 1955, to present papers and discuss current problems dealing with the structure and metabolism of bone. The proceedings of these meetings are compiled in a "Ciba Foundation Symposium." There were many important presentations.
 Arne Engstrom applied his methods of quantitative roentgen microscopy to osseous tissues. The slowly mineralized structures in bone tissue are in a state of very rapid cxchange with body fluids and act as an effective ion-exchange column.


Fungi and products based thereon are increasingly gaining in importance as flavours in the manufacture of foodstuffs The submerged fermentation of edible mushrooms and the recovery of mycelium cultivated by submerged fermentation to obtain a product containing 1‐octen‐3‐ol are discussed. 1‐octen‐3‐ol is the component typical of fungal flavours. Its formation depends upon the mycelium being subjected to shear stress, whereby fungal enzymes convert linoleic acid into 1‐octen‐3‐ol (W. Grosch et.al. 1985). By concentrating and drying the mycelium thus treated, products containing approx. 2.500 ppm 1‐octen‐3‐ol are obtainable. W. Grosch, M. Wurzenberger: Enzymic formation of 1‐octen‐3‐ol in mushrooms. Dev Food Sci. 10 (Prog. Flavour Res.) 253–9 (1985).


We report on a patient who developed donor‐derived cutaneous T‐cell lymphoma (CTCL) 4 years after successful treatment of chronic myeloid leukaemia with an allogeneic bone marrow transplant. The patient developed an eczematous rash unresponsive to topical therapy and immunosuppression. When CTCL was diagnosed in the recipient, his sibling donor had been attending his local dermatology unit with a maculosquamous rash, which proved subsequently to be mycosis fungoides. An identical pattern of donor and recipient clonality assessment and T‐cell receptor gene sequencing indicated that the CTCL was probably transmitted in the bone marrow harvest. This suggests that CTCL cells circulate in the marrow at an early subclinical stage in this disease. This is the second case of donor‐derived CTCL reported to date.


The History of Tom Jones is one of English realism novelist Henry Fielding's masterpieces.In this novel,Henry Fielding set up a multi-level and multi-angle contrast structure,by using which he not only created a series of vivid characters,but also clarified the theme of this great work powerfully.