In this paper we present a method to classify urban scenes based on a super-voxel segmentation of sparse 3D data. The 3D point cloud is first segmented into voxels, which are then joined together by using a link-chain method rather than the usual region growing algorithm to create objects. These objects are then classified using geometrical models and local descriptors. In order to evaluate our results a new metric is presented, which combines both segmentation and classification results simultaneously. The effects of voxel size and incorporation of RGB color and intensity on the classification results are also discussed.


Contradicted results have been reported on sensitivities of Cr‐Mo low alloy steels to fracture toughness, so it seems further investigations is required in order to establish the reasons for this contradictions. This study tried to rationalize the causes of contradiction and establishes the reasons for variations in the observed changes in fracture toughness of two types of low alloy steels namely 3Cr‐1Mo and 2.25Cr‐1Mo steels. For investigating the embrittlement sensitivity in this research, a factor called J used since there are some clams that Cr‐Mo low alloy steels with higher J-Factor are more sensitive to temper embrittlement. For inducing temper embrittlement on these alloys, a step-cooling operation from high temperature to room temperature for a period of 234 h was employed. Then some of the mechanical properties of the embrittled sample and unembrittled alloys were determined and compared. The results showed that step cooling operation had no noticeable effect on tensile and hardness properties of the steels but strongly affected their resistance to impact. In the alloy having a low J-Factor of equivalent to 107, changes in both FATT and TT54J were about 11°C, this was relatively low, while in the alloy having a high J -Factor equivalent to 224, these changes were 70°C and 78°C respectively which indicated this alloy was highly sensitive to temper embrittlement. Changes in temper embrittlement of the two alloys used in this research were found and we tried to justify these changes in this article.


Malignant melanoma of skin is one of the deadliest forms of cancer.If detected not timely,it can not be treated effectively and the risk of recurrence remains.Therefore,how to improve the life quality of patients has become an important topic in medical field.In this study,we evaluated life quality of 40skin's malignant melanoma patients in different clinical stages with Chinese version 3.0of EORTC QLQ-C30scale and questionnaires.The results were analyzed and compared witht-test and factor analysis method by SPSS 17.0version and showed the common factors had greater load on standard scores of fatigue,depression,loss of appetite atⅠandⅡ phases and of physical function,cognitive function,nausea and vomiting,pain,economic hardship atⅢandⅣ phases.We conclude that clinicians can improve life quality of skin's malignant melanoma patients in different clinical stages scientifically with Chinese version 3.0of EORTC QLQ-C30 scale.


The Shanxi Pingshun region is located in the west limb of a large-scale anticline of Taighang Mountain and is to the southeast of the Taihang upwell of Luliang-Taihang fault block.It is one of the most important skarn iron ore concentration areas in North China.The Mesozoic dioritic rock was the source rock for skarn Fe deposits.In this paper,the work carried out on zircon SHRIMP dating and geochemical analysis of Mesozoic magmatic rocks is described.The results of zircon ages for the gabbro and diorite were 123 Ma and 126 Ma,respectively(within the same intrusion periods).Magmatic rocks in the region were metaluminous high-K calc-alkaline series rocks and all the samples(Erfengshan diorite,Xi′anli gabbro and diorite) were characterized by similar REE patterns with enriched LREE(ΣLREE on average is 94.64 μg/g,110.73 μg/g and 118.63 μg/g).The fractionation between LREE and HREE was not very strong since(La/Yb)N on average were 9.47,9.17 and 9.70.The Eu anomaly was not obvious as δEu on average were 1.00,0.96 and 1.04.The gabbro and diorite were enriched Ba,Th,U,and other LILEs had the characteristic of high Sr and strongly depleted HFSEs(Nb,Ta).Combined with previous research results,indications are that the magmatic rocks were mainly from the mixing members between mantle-derived magma and the low crust-derived magma.High Nb/Ta(17 to 22,on average is 19) and Zr/Hf values(35 to 40,on average is 37) were inherited from the magmatic source features.This indicated that the mantle source was replaced by subducted slab melt/fluid.The geodynamic setting is Mesozoic destruction and a lithospheric thinning event in the North China Craton.However,the diversity of the mechanism should also be noted.


In our previous studies, a AlGaN/GaN HEMTs (High Electron Mobilty Transistors) demonstrated a sharp drain current phenomenon in a cryogenic environment, which is not confirmed at room temperature. This phenomenon was not derived from the self-heating effect of GaN-HEMT but was considered as a current collapse phenomenon caused by crystal defects at the interface between i-GaN and AlGaN. In this study, we investigated IV characteristics change of AlGaN / GaN HEMT against ambient temperature change by changing drain voltage to pulse voltage. By a pulse of drain voltage, in addition to the pulse response when the two-dimensional electron gas carrier ware swept, the two response peaks were confirmed. One of them showed fluctuations that followed the temperature change. The temperature change of the response time constant of this peak was calculated, and the activation energy was calculated from the Arrhenius plot. The calculated activation energy was 0.575 eV, which agreed well with the literature value. It was suggested that the IV characteristic change due to the temperature change is caused by the current collapse phenomenon due to the carrier trap to the AlGaN layer. As a result of this study, it was shown that the identification of the crystal defect order in the AlGaN crystal becomes apparent from the analysis of the transient response characteristic of the drain pulse voltage.


Normally, rats, who have been exposed to allergens during the first weeks of life will show a tolerance to the antigen after a brief IgE antibody response (1). We can also see this in infants (2). When the individual, at the time of initial exposure to an antigen, is simultaneously exposed to certain risk factors, the immune response may instead steadily increase. This expands the pool of memory T cells and this effectively primes the immune system. You will have then built a foundation of hypersensitivity to the allergen. Once an allergic inflammatory response to an allergen occurs, the process in turn enhances sensitization to new allergens.


The dynamics of the productive behavior of immigrants arriving from outside the European Union comprise the phase preceding the immigration, the phase of first permanent residence, and the phase of secondary socialization to labor. The extra-community labor migration carries within itself all the individual cultural patrimony (values, conduct, faith, identity, lifestyle) which are invested into the transformation process and change through contact with the other culture. The differentiated labor-specific evolution of the extra-community migration was analyzed by means of a mathematical formula using the variables of compensation for work (salary), performance (effort), immigration, socialization to work, and the economic impact of differential work contribution, all of which individually and jointly exert an effect on the labor market. In the regular Italian labor market there is, however, a surplus; the irregular (underground) economy is differentiated by the variable of effort that immigrants exert in order to obtain employment. Labor behavior is determined by the competitiveness of the labor force and dangers inherent in leaving one's country and entering a foreign land illegally. Statistically, in the long term, individual situations show a diminishing trend vis-a-vis the risk of repatriation connected to the loss of the residency permit because of gradual integration into the labor market. The initial labor-specific effort (salary/performance) is reduced vis-a-vis a progressive process of socialization owing to work. New lifestyles and consumption patterns are acquired which also facilitate social integration. The human capital of the immigrant increases by progressive acquisition of language and other cultural instruments.


Agriculture productivity mainly depends on Indian economy. Hence, Disease prediction plays a important role in agriculture field. In image analyzing the symptoms is an essential part for feature extraction and classification. However, some of the challenges are still lacking to predict the disease. To meet those challenges, the proposed algorithm focuses on a specific problem to predict the disease from early symptoms. Bacterial Leaf Blight and Brown Spot are a major bacterial and fungal disease respectively in rice (Oryza sativa) crops, it causes yield loss and reduce the grains quality. This research work focused on automatic detection method for image segmentation on rice leaves under wide range of environmental condition for further analysis. Various hybrid techniques for image segmentation and classification algorithms were analyzed and an automatic detection method has been proposed for identifying the specified diseases in rice leaves under different environmental condition.


GUIDO Luiza N. Paternal nutrition and cancer programming: the influence of selenium deficiency or supplementation on the susceptibility of female offspring to chemicallyinduced mammary carcinogenesis. São Paulo, 2016. PhD Thesis – Faculty of Pharmaceutical Sciences, University of São Paulo. Breast cancer is an important public health problem. As mammary gland development is a dynamic process that initiates in embryonic life, recent evidence show that in-utero life exposure to maternal nutritional factors can alter mammary gland development and program breast cancer risk in adult life. Even tough studies focus on maternal nutrition, recent evidence show that paternal nutritional factors in-utero and during preconception also affects their female offspring mammary gland development and breast cancer susceptibility in adult life. Studies highlight epigenetic modulation of gene expression in the mammary gland as possible breast cancer programming underlying mechanisms. Selenium is a micronutrient with essential role in central aspects of embryogenesis, male fertility and that has been extensively studied as a chemopreventive agent in several breast cancer models. Among selenium possible mechanisms of action, modulation of cell proliferation, apoptosis, DNA damage, gene expression and epigenetic marks are highlighted. Thus, a rat experiment was conducted to evaluate whether paternal selenium deficiency or supplementation during preconception could affect mammary gland development and breast cancer risk, as well as possible molecular mechanisms involved. Four-week old male Sprague-Dawley rats were exposed to experimental diets (AIN93G) containing 0.15 (control), 0.05 (deficient) and 1ppm (supplemented) of selenium as sodium selenate for 9 weeks and mated with control females. At 7-week old, mammary carcinogenesis was induced in their female offspring by oral administration of 7,12 dymethylbenz[a] anthracene and mammary neoplasia development was evaluated. Paternal selenium deficiency during preconception altered mammary gland development as increased terminal end buds (TEBs) number, epithelial elongation and cell proliferation and decreased apoptosis that were associated with increased breast cancer risk (higher incidence and grade tumors). In addition, paternal selenium deficiency during preconception induced molecular alterations in the mammary gland of the female offspring such as global DNA hypomethylation, increased global levels of H3K27me3 and altered expression of genes related to early life and mammary gland development, apoptosis, cell cycle control, and DNA damage repair. Paternal selenium supplementation during preconception on the other hand did not influence breast cancer programing. Our data show that breast cancer risk can be determined in early-life stages trough the male germline molecular modulation and preconception as an important window of opportunity to start breast cancer prevention strategies. Assuring and adequate selenium intake by men could be a possible starting point. Key-words: selenium, paternal nutrition, breast cancer, mammary gland development, female offspring, rats. List of abbreviations Abcg2 – ATP-binding cassette, sub-family G, member 2 ABs – Alveolar buds AIN – American Institute of Nutrition Ang-2 – angiopoietin-2 ANOVA – Analysis of variance Bax – BCL2 Associated X Protein Bcl-2 – B-Cell CLL/Lymphoma 2 BORIS – Brother of the regulator of imprinted sites BRAC1 – Breast cancer 1 gene BRAC2 – Breast cancer 2 gene BSA – Bovine serum albumin Ccnd2 – Cyclin D2 cDNA – Complementary DNA CH3OH – Methanol CH3SeH – Methylselenol CO – Control CTCF – CCCTC-binding factor DMBA – 7,12-dimethylbenz[a]anthracene DNA – Deoxyribonucleic acid DNMT1 – DNA methyl-transferase 1 DOHaD – Developmental origins of health and disease EFSA – European Food Safety Authority FoRC – Food research center Gata3 – GATA binding protein 3 Gpx – Glutathione peroxidase Gpx1 – Glutathione peroxidase 1 Gpx2 – Glutathione peroxidase 2 Gpx3 – Glutathione peroxidase 3 Gpx4 – Glutathione peroxidase 4 H2Se – Selenide H3K27me3 – Histone 3 lysine 27 tri-methylated H3K9ac – Histone 3 lysine 9 acetylated H4K16ac – Histone 4 lysine 16 acetylated HB – Hemoglobin HCl – Hydrochloric acid HIF-1α – hypoxia inducible factor-1 alpha HPLC – High-performance liquid chromatography HPLC-DAD – High-performance liquid chromatography with diode-array detection HPLC-FLD – High-performance liquid chromatography with fluorescence detection Igf1 – Insulin like growth factor 1 Igf1r – Insulin like growth factor 1 receptor Igfbp3 – Insulin-like growth factor binding protein 3 INRA – Instituit National de la Recherche Agronomique Ki67 – Marker Of Proliferation Ki-67 LBs – Lobules MDA – Malondialdehyde MgCl2 – Magnesium chloride Mgmt – O-6-Methylguanine-DNA Methyltransferase miRNAs – micro ribonucleic acid mRNAs – messenger ribonucleic acid MSA – methylseleninic acid PBS – Phosphate-buffered saline PGCs – Primordial germinative cells pH – Potential of hydrogen Pten – of phosphatase and tensin homolog qPCR – Quantitative real time PCR RDA – Recommended dietary allowances RNA – Ribonucleic acid RNAt-Sec – Selenocysteine RNA transporter ROS – Reactive oxygen species S.E.M – Standard error of mean Se – Selenium Se-DEF – Selenium deficient Se-GTPs – selenium-containing tea polysaccharides SePP – Seleno protein P Se-SUP – Selenium supplemented TBS-T – Tris-Buffered Saline-Tween TDLUs – Terminal ductal lobular units TEBs – Terminal end buds TrxR – Thioredoxine reductase VEGF-alpha – vascular endothelial growth factor-alpha β-actin – Beta actin


I prove general combinatorial properties which apply to singular Artin monoids and examine their relationship with the Vassiliev homomorphism ≠. I show that ≠ preserves the Intermediate Property, discovered by Corran, which holds in positive singular Artin monoids of finite type. From this it follows that ≠ is injective for a class of monoids which include singular Artin monoids of type I2(p), generalising a result of East.


Differential spectra for electron production in the forward direction have been obtained by collision of H2+ and He+ ions with H2, He, Ne and Ar gases. The measurements where made with ions of energy 0.8-2.8 MeV. The target consisted of a jet of gas from a multicapillary array, thereby providing a well localised and directed gas beam. A 30 degrees parallel-plate electrostatic analyser having a FWHM resolution (dE/E)=10-3 was used to study the energy of the ejected electrons. A cusp-shaped peak centred on ve=vi was observed for all the electron spectra, suggesting that these electrons were ejected with only a small energy relative to the parent ions. This process has been called electron loss to the continuum (ELC) since in some ways it mimics the now well established phenomenon of charge exchange to the continuum (CEC). In contrast to data for ELC from heavy ions the cusps observed here were generally asymmetric. They did, however, show a width approximately independent of projectile velocity, a feature which seems to distinguish ELC from CEC. Both the cusp shapes and widths are compared with theoretical predictions and other experimental measurements.


Introduction. A retained surgical sharp (RSS) is a never-event and defined as a lost sharp (needle, blade, instrument, guidewire, metal fragment) that is not recovered prior to the patient leaving the operating room. A near-miss sharp (NMS) is an intraoperative event where there is a lost surgical sharp that is recovered prior to the patient leaving the operating room. With underreporting of such incidents, it is unrealistic to expect aggressive development of new prevention and detection strategies. Moreover, awareness about the issue of near miss or retained surgical sharps remains limited. The aim of this large-scale national survey-based study was to estimate the incidence of these events and to identify the challenges surrounding the use of surgical sharps in daily practice. Methods An IRB approved and anonymous national survey composed of eleven questions was distributed electronically to operating room team members across the United States. There were 447 survey responses, in which 411 were used for further analysis. 36 responses were removed due to incomplete respondent data. The 411 were then categorized by group to include 94 (22.9%) from anesthesiologist, 132 (32.1%) from resident/fellow/attending surgeon and 185 (45%) from surgical nurse and technologist. Results. Overall, most of each respondent group reported 1-5 lost sharp events over the last year. Roughly 20% of surgeons believed they never had a miscounted sharp over the last year, where only 5.3% of anesthesiologist reported the same (p=0.002). Each group agreed that roughly 4 lost events occur every 1,000 surgeries, but a significant difference was found between the three groups regarding the number of lost sharps not recovered per 10,000 surgeries with anesthesiologist, surgeon and nurse/technologist groups estimating 2.37, 2.56 and 2.94 respectively (p=0.001). All groups noted x-ray to offer poor effectiveness at 26-50% with 31-40min added for each time x-ray was used. More than half (56.8%) of surgeons reported using x-ray 100% of the time when managing a lost sharp whereas anesthesiologists and nurses/technologists believe it is closer to 1/3 of the time. An average of 21-30min is spent managing each NMS, making a lost sharp event result in up to 70min of added OR time. Conclusions. Near miss and RSS are more prevalent than what is reported in current literature. Surgeons perceive a higher rate of success in retrieving the RSS when compared to anesthesiologists and OR nurses/technologists. We recognize several challenges surrounding near miss and never events as contributing factors to their underreported nature and the higher degree of surgeon recall bias associated with these events. Additionally, we highlight that current methods for prevention are costly in time and resources without improvement in patient safety. As NMS and RSS have significant health system implications, a strong understanding of these implications is important as we strive to improve patient safety.


Research on early childhood education emphasises the importance of quality in early childhood intervention. This study examines the quality of Early Childhood Intervention Services based on parents' experiences raising a child with developmental delay or disability. The study builds on the philosophy of Family-Centred Practice and professionals' experiences with family-centred interventions. A qualitative case study approach was adopted to gain insight about families who are raising a child with additional needs. Nine in-depth parent-interviews and three focus groups with professionals were conducted in the first two terms of 2010. The case explicates the experiences of parents and professionals who were associated with Specialist Children's Services in a metropolitan region of Victoria. The research concentrated on the first point of entry to early intervention, the referrals process and the waiting list. It also addressed parents' experiences, priorities and expectations. As a small-scale study, it examined parents' and children's needs as well as children's access to therapy in early intervention. It also investigated community support and parent-professional relationships in the context of early childhood intervention services. The study found that family-centred intervention is beneficial to both parents and children with developmental delay or disability. However, to implement an effective family-centred approach, practitioner support in the form of professional development, supervision and peer mentorship is required to develop professionals' reflexivity and self-efficacy in family-centred interventions. The study also identified strategies to promote effective practice, gaps in universal and specialised services, and implications for policy.


This study aims at examining the transitivity processes occurred in the characters' action in Joseph Jacobs's Fairy Tales. Language style for children literature has its distinction from other fictions. Such lexical and the dictions selection become its focus primarily at the main figure's action. The purpose of this study is not only to provide worthwhile information particularly at the language style of literature for children in case of Joseph Jacobs's fairy tales but also to remedy the neglected focus on the earlier studies which analyzes the mentioned object as well. This study used the methodology of descriptive qualitative research. To analyze the research objective, this study used Halliday's transitivity theory which examines the processes of a sentence. Based on the data analysis, the results found 56 data in total contained with several processes as follows; 30 material processes, 5 mental processes, 5 behavioural processes, 4 verbalization, 3 relational processes, and an existential processes.


This study conducted IRT(Infrared Themography) test for Small Bore Pipe specimen artificial Wall Thinning defect to find an optimal condition for IRT for Wall Thinned nuclear Piping components. In the Experiment two Halogen Lamps, whose full power capacity are 1 kW, werw used to heat specimens, and the exposure distance between specimen and Lamp and the Lamp power were considered as experimental parameters. Image of defect in Small Bore Pipe specimen was clearer under the conditions of higher Lamp power and shorter exposure distance than under the conditions of lower Lamp power and longer exposure distance. Also, it was indicated that IRT showed similar detectability for Small Bore Pipe specimens, but the optimal test condition for IRT depended on the specimen type.


Chief physician Wang Zili could make the best use of modified HuoPo XiaLing Tang in clinic for miscellaneous diseases of internal medicine. He emphasizes that we should analyze the data gained by four diagnostic methods in clinic comprehensively, but taking tongue diagnosis as the evidence mainly; especially white, thick and greasy, or yellow, thick and greasy tongue coating as the main evidence of syndrome differentiation, when we treated miscellaneous diseases of internal medicine by modified HuoPo XiaLing Tang. The paper is discussing three effective cases including vertigo, stomachache and stranguria, therefore to provide academic experience of chief physician Wang Zili.


The seasonal change in milk supply and composition of milk (fat, casein, whey protein and lactose concentration) determine the type and value of dairy products that can be manufactured by a dairy processing plant over the season. Milk composition can be manipulated on-farm using a number of methods. Those methods include animal breeding, feeding, altering calving and lactation patterns, interfering with the physiological pathways and manipulating the rumen micro-organism. This paper describes the use of a Dairy Supply Chain Model (DSCM) to study how market demand for dairy products, and how changes in milk composition at the farm level impact on manufacturing performance of the New Zealand Dairy Industry. The DSCM was developed in SDI Industry Pro, a dynamic simulation software, and Microsoft Excel using the Solver add in, a mathematical programming application. The DSCM was developed to mimic standard supply chain management functions which include (a) placing of orders for dairy products so that inventories at demand centres were not depleted, (b) assigning orders to the suppliers of products, (c) manufacturing and creating a shipment of product, and (d) routing the order to its destination. Other features included the ability to specify a milk supply schedule, outline product demand profiles for 15 dairy products, define inventory replenishment policies, and optimise the type and quantity of dairy products that can be manufactured. Supply chain performance was assessed taking into account manufacturing profit and inventory related costs. The effects that modifying the composition of casein in milk has on the dairy product mix and on supply chain performance is reported in this paper. The information can be used to prioritise research and development in the dairy sector.


It is reported that inorganic ferric ion immobilized onto a phosphonic acid terminated functional interface can communicate an electron with the electrode and its electrochemistry is very similar to that of the enzymes (proteins) containing heme groups (such as microperoxidase, horseradish peroxidase, hemoglobin, and myoglobin). For example, its formal potential (E0′) is very close to that of the above-mentioned enzymes (proteins) in neutral solution; analogous to the direct electrochemistry of enzymes (proteins), the formal potential and electron-transfer rate of the immobilized inorganic ferric ion show a strong dependence on solution pH in cyclic voltammetry measurements. In comparison to the traditional enzyme (proteins)-based electrochemical biosensors, the ferric ion modified electrode shows more prominent electrocatalytic activity toward the reduction of hydrogen peroxide due to its high loading, fast electron-transfer rate, and excellent selection toward the reduction of hydrogen peroxide. Importa...


One of the possible sources of scandium production – waste (slags) from processing of oxidized nickel ores, has been considered in present research work. The hydrometallurgical method has been selected as the primary for scandium extraction. Different reagents for leaching of scandium, such as sulfuric acid, various carbonate salts and fluorides, have been tested. Sulfuric acid has been recognized as an optimal leaching reagent. Sulfuric acid concentration of 100 g L−1 allowed recovering up to 97 % of scandium.


Background
 Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an extremely rare hematologic malignancy affecting 1.5-2.0 per million adults per year worldwide, which corresponds to approximately 1,000 cases in Europe. It is a highly aggressive disease characterized by skin and bone marrow involvement, with secondary sites including lymph nodes and viscera. BPDCN is associated with a poor prognosis, median overall survival of 8-14 months, and has no firm consensus for therapy. Tagraxofusp (TAG, SL-401) is currently the only approved first-line treatment for adult patients with BPDCN in Europe. TAG is a targeted therapy directed to CD123 that has shown efficacy in a controlled, prospective trial with prespecified endpoints. Specifically, TAG is a recombinant cytotoxin composed of human interleukin-3 fused to a truncated diphtheria toxin payload that targets CD123, the α-subunit of interleukin-3 receptor commonly overexpressed on the surface of BPDCN tumor cells. In the past, most adult and pediatric patients in Europe were treated with a plethora of experimental combination chemotherapies often imported from aggressive myeloid and lymphoid malignancy treatment regimens, followed by hematopoietic stem cell transplantation (SCT), as best available treatment. However, there is no robust evidence of the effectiveness and safety of these therapies for BPDCN, due to its rarity, the absence of prospective studies, and the variability in diagnostic criteria, definition of endpoints, and assessment of outcomes. As of July 2021, 65 patients with BPDCN have been treated with TAG in a clinical setting outside the US, as part of an expanded access program. Continued collection of clinical data from the use of TAG in a real-world setting in patients with BPDCN is important to increase the knowledge of clinical outcomes, especially in patient populations commonly underrepresented in clinical trials. This is the first real-world evidence prospective registry in patients with BPDCN receiving TAG. The study is designed to meet the requirements included in the marketing authorization by the European Commission, to further investigate the effectiveness and safety of TAG in the treatment of patients with first-line or relapsed/refractory BPDCN.
 Study Design and Methods
 This is a noninterventional, single-arm study (EudraCT: 2021-001684-24) in patients with BPDCN to assess clinical effectiveness and safety of TAG under real-world routine clinical practice conditions (12 mcg/kg intravenously [IV] once daily on days 1-5 of a 21-day cycle, per the summary of product characteristics general recommendation). Up to 125 patients are planned for inclusion in approximately 65 clinical sites in Europe estimated over 3 years. Eligible patients have a diagnosis of BPDCN and are scheduled to start TAG monotherapy, per physician's decision.
 The primary study objectives are to determine the complete response (CR) rate, defined as CR + clinical CR (CR with residual skin abnormality not indicative of active disease) after 3 months of treatment, and to assess the safety of TAG, in particular the incidence and severity of capillary leak syndrome (CLS). Secondary objectives include analysis of the rate of patients bridging to SCT, progression-free survival, overall survival, best overall response, duration of response, dose interruptions/administration of IV albumin supplementation in patients with CLS or CLS symptoms, incidence and severity of adverse events of special interest (AESIs), overall safety, and TAG treatment administered. AESIs include CLS and hepatic, renal, and cardiac events.
 Per routine clinical practice, quarterly data collection is anticipated during the study. In addition, data will be collected at screening, enrollment, early discontinuation, and study end (Figure). The end of the registry safety data collection will be 18 months after the last enrolled patient's first visit (LPFV). Interim analyses will be performed annually, and an effectiveness interim analysis is scheduled at 12 months post-LPFV. All effectiveness and safety analyses will be performed using descriptive statistics. Survival data will be summarized using the Kaplan-Meier method. Subgroup analyses for effectiveness and safety may be performed, on the basis of gender, age, or Eastern Cooperative Oncology Group performance status at baseline.
 Enrollment is planned to start by December 2021.
 Figure 1 Figure 1.

 Platzbecker: Celgene/BMS: Honoraria; Novartis: Honoraria; Janssen: Honoraria; Takeda: Honoraria; AbbVie: Honoraria; Geron: Honoraria. Angelucci: Menarini-Stemline: Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: steering commitee, Speakers Bureau; Vertex Pharmaceuticals: Honoraria, Other: DMC; Celgene BSM: Honoraria, Other: DMC; Blue Bird Bio: Honoraria, Membership on an entity's Board of Directors or advisory committees; Novartis: Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Crispr therapeutics: Honoraria, Other: DMC; Glaxo: Honoraria, Membership on an entity's Board of Directors or advisory committees; Gilead: Honoraria, Membership on an entity's Board of Directors or advisory committees. Montesinos: Glycomimetics: Consultancy; Teva: Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau; Sanofi: Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Incyte: Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Tolero Pharmaceutical: Consultancy; Janssen: Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau; Forma Therapeutics: Consultancy; Pfizer: Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau; Celgene: Consultancy, Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau; Daiichi Sankyo: Consultancy, Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau; Karyopharm: Membership on an entity's Board of Directors or advisory committees, Research Funding; Novartis: Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau; Agios: Consultancy; AbbVie: Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau; Astellas Pharma, Inc.: Consultancy, Honoraria, Other: Advisory board, Research Funding, Speakers Bureau; Stemline/Menarini: Consultancy. Lemoni: AbbVie: Membership on an entity's Board of Directors or advisory committees; Janssen: Membership on an entity's Board of Directors or advisory committees; Jazz: Membership on an entity's Board of Directors or advisory committees; Daiichi Sankyo: Membership on an entity's Board of Directors or advisory committees; Servier: Membership on an entity's Board of Directors or advisory committees; Stemline Therapeutics: Membership on an entity's Board of Directors or advisory committees; Celgene: Research Funding. Spyridonidis: Menarini: Current Employment. Casariego: Menarini: Current Employment. Mughal: Stemline: Current Employment, Current holder of stock options in a privately-held company; Oxford University Press, Informa: Other: financial benefit and/or patents . Mohty: Sanofi: Honoraria, Research Funding; Pfizer: Honoraria; Novartis: Honoraria; Takeda: Honoraria; Jazz: Honoraria, Research Funding; Janssen: Honoraria, Research Funding; Gilead: Honoraria; Celgene: Honoraria, Research Funding; Bristol Myers Squibb: Honoraria; Astellas: Honoraria; Amgen: Honoraria; Adaptive Biotechnologies: Honoraria.


This paper is aimed to explain the dynamics and the social conflict process through the processes of orientation, actions, strategies, interaction and reception in local and regional dynamics; which are considered to explain the dynamics of the process of social conflict in Marmato, Caldas (2007-2012). The following questions are posed: How do actors and organizations interpret and construct a conflictive situation? How do the actors involved dis- pute their interests and seek solidarity and legitimacy from broad sectors of society? The methodology consisted of a case study based on a series of interviews with local leaders and students, review of written statements, videos and virtual pages, along with a literature review that allowed an in-depth reconstruction of the case. It was concluded that the endogenous character of the social struggle, added to the conflicts that precede the mega mining conflict, and the role played by external sectors, it will be fundamental to build an articulated dynamic around specific living conditions that local actors created around traditional small-scale mining.


Abstract:Demographic and technological changes are two megatrends set to transform labour markets around the world. These shifts are already under way and are expected to accelerate, particularly in East and Southeast Asia, which is home to the world's oldest and fastest-ageing societies and a region with an enviable pace of economic development. Yet for some countries, demographic ageing is coinciding with a slowdown in productivity and economic growth. While each of these phenomena has been extensively researched, the study of the interactions between them is often incidental and rarely carried out in the Asian setting. This article explores the plausible channels of these interactions and assembles evidence of links between age and productivity at the individual, firm and country levels, drawn from both Asian and global settings. Findings have shown that there are many knowledge gaps, both in data and modelling, which need to be addressed to inform the major policy interventions required to successfully manage these transitions.


The principle, system composition, application examples and current study current of automatic control of main process such as gravity separation, flotation, clean-up of slime water and TBS separation in the coal washery were introduced. Analysis results indicated application of automatic control of main process was contributive to improving operation stability of coal washery, reducing operation cost, ensuring quality of clean coal and increasing economic benefit.


Systemic ventricular failure is a recognised late consequence of the atrial switch procedure for transposition of the great arteries. There is a significant population status post atrial switch. We report one such patient with a failing Mustard procedure who was treated by surgical implantation of a Heartware HVAD rotary blood pump into the systemic ventricle. Babar B Chaudhri* Department of Cardiac Surgery, KG Mittal Hospital, Mumbai 400004, India


Objective
To investigate the relationship between occurrence of nonalcoholic fatty liver disease (NAFLD) and serum uric acid level in patients with type 2 diabetes mellitus (T2DM).

Methods
A total of 225 elderly patients with T2DM, over 60 years old, admitted to the First Affiliated Hospital of Zhengzhou University from December 2017 to August 2018 were selected as research objects. And their clinical data were retrospectively analyzed. Among them, 122 patients with NAFLD were allocated into DN group, and 103 patients without NAFLD were set as DM group. Age, body mass index (BMI), serum uric acid, total bilirubin (TBIL), direct bilirubin (BILD), indirect bilirubin (IBLD), total bile acid (TBA), alanine aminotransferase (ALT), aspartate aminotransferase (AST), glutamyl transpeptidase (GGT), triglyceride (TG), total cholesterol (TCHO), low density lipoprotein-cholesterol (LDL-C), high density lipoprotein-cholesterol (HDL-C), glycated hemoglobin (HbA1C) of all patients were recorded and analyzed.

Results
The levels of uric acid, ALT, AST, GGT, BMI and TG in DN group were significantly higher than those of DM group, however, the age and course of disease of DN group were significantly lower than those of DM group, and the difference was statistically significant (P<0.05). Logistic regression analysis showed that BMI, blood uric acid and TG were independent risk factors of occurrence of NAFLD in elderly T2DM patients (P<0.05).

Conclusions
There is a close independent correlation of serum uric acid, TG and BMI with NAFLD in elderly T2DM patients. It is necessary to focus on the control of blood uric acid in elderly patients with T2DM to reduce the occurrence rate of NAFLD.

Key words:
Blood uric acid; Elderly; Type 2 diabetes mellitus; Nonalcoholic fatty liver


The structure, magnetic properties and thermal properties of the ζ-phase and µ-phase of the Pd 3 Mn 2 alloy were investigated. The ζ-phase has a b.c.t. lattice with the CsCl-type superstructure, while the µ-phase has a modified form of the ζ-phase superstructure. Both phases are antiferromagnetic, but in the µ-phase the susceptibility below the Neel point is strongly dependent on the field strength. The excess heat absorption at the Neel point is 510 cal./mol. (Pd 15 Mn) for the µ-phase, 890 cal./mol. (Pd 15 Mn) for the ζ-phase, and the heat of transformation from µ to ζ is 180 cal./mol. (Pd 0.6 Mn 0.4 ) These results are discussed on the basis of the two sublattice model of an antiferromagnet.


2-Fluorotoluene has been nitrated regioselectively for synthesizing 2-fluoro-5-nitrotoluene under mild conditions using different zeolite catalysts.Under acetic anhydride,the effects of the different zeolite catalysts on 2-fluorotoluene nitration were obtained with fume nitric acid as nitrating agent.The results showed that H-beta zeolite had higher conversion and selectivity in all isomers due to higher acidity.As the 25% amount of H-beta catalyst for 2-Fluorotoluene,1.20∶1.05∶1.0 molar ratio of acetic anhydride∶fume nitric acid∶2-fluorotoluene were used,2-fluorotoluene at-5 ℃ and 2 h aditione time showed 99.5% convertion with 85% selectivity for 2-fluoro-5-nitrotoluene.By simple seperation,higher pure 2-fluoro-5-nitrotoluene was obtained in the yield of 75%.A recycling study of catalyst H-beta for nitration of 2-fluorotoluene showed no significant loss in conversion as well as selectivity even after 5 recycles indicating the high stability of the catalyst.Compared to the conventional process,2-fluorotoluene nitration over H-beta acid catalysts is a highly regioselective,environmentally friendly process with a simpler work up procedure.


We present a broad suite of models of extrasolar giant planets (EGP's), ranging in mass from 0.3 to 15 Jupiter masses. The models predict luminosity (both reflected and emitted) as a function of age, mass, deuterium abundance and distance from parent stars of various spectral type. We also explore the effects of helium mass fraction, rotation rate and the presence of a rock-ice core. The models incorporate the most accurate available equation of state for the interior, including a new theory for the enhancement of deuterium fusion by electron screening which is potentially important in these low mass objects. The results of our calculations reveal the enormous sensitivity of EGP's to the presence of the parent star, particularly for G and earlier spectral types. They also show a strong sensitivity of the flux contrast in the mid-infrared between parent star and EGP to the mass and age of the EGP's. We interpret our results in terms of search strategies for ground- and space-based observatories in place or anticipated in the near future.


This paper provides a review of merger and acquisition literature that have examined the theories, the impact of M&A towards banking performance, both conventional and Islamic, as well as the factors associated with M&A activity. The authors have been able to review more than thirty investigations over a twenty-year period, from 1993 to 2017. The study is theoretical and analytical in nature and secondary method has applied. Through a literature review, this study provide an account of the theories and main findings of the literature as well as examines the extent to which M&A give impact to the banking performance and highlights some factors contribute to the successfulness of M&A activity. Overall, the evidence reviewed suggests that M&A affect the conventional and Islamic banks in several different ways. This could be explained by different approaches in handling M&A (i.e., domestic or cross border) and various factors contributing to the decision of conducting the M&A activity. As far as the development and increase interest in Islamic finance are concerned, it is perhaps surprising that very little empirical research on M&A in Islamic banking sector. The paper concludes with several recommendations for future research, the most important of which is the need for a systematic effort on conceptual analysis as well as empirical study on M&A in Islamic banking and finance. Keyword: Merger and Acquisition, theory, bank performance, Islamic banking PhD student, Faculty of Economics and Muamalat, Universiti Sains Islam Malaysia, Malaysia. Senior Lecturer, Faculty of Economics and Muamalat, Universiti Sains Islam Malaysia, Malaysia. email@example.com


y-Aminobutyric acid inhibits interleukin-ip stimulated release of interleukin-6 from rat C6 glioma cells in vitro: Evidence for role of p38 MAP Kinase by Raghuram Royyuru Dr. Bryan L. Spangelo, Examination Committee Chair Professor University o f Nevada, Las Vegas The central nervous system (CNS) is composed of two cell types neurons and glial cells. Neurons mediate the function of sending and receiving signals in the brain. Glial cells provide nutrients and strength to the CNS. Glial cells are composed of microglia, oligodendroglia, and astrocytes. Activated microglia is the main source for the cytokine interleukin-1 (IL-1). Activated cytokines are elevated in Alzheimer's disease (AD) (Tuppo, 2005), a neurodegenerative disorder. Cytokines mediate the inflammatory response, which is required for cells to carry out part of its normal functions. When inflammation is chronic it damages the cells and leads to the adverse effects like neuronal death which is a primary symptom for AD. IL-lp stimulates IL-6 through by activation of a series o f complexes, involving mitogen activated protein kinases (MAPK) and transcription factors. Increased lL-6 leads to neurodegeneration and finally leads to the death o f the patient. IE-1P is activated by


Gait Disorders of Aging. Falls and Therapeutic Strategies . Edited by joseph c masdeu, lewis sudarsky,and leslie wolfson. (Pp 350; £61.00.) Published by Lippincot -Raven, Philadelphia. 1997. ISBN 0-316-54915-0.

Community studies show that around 30% of people aged 65 and over fall each year. Only 10% to 15% of falls result in serious injury but 92% of hip fractures and 96% of wrist fractures in older women are caused by falling. There are important consequences even when no serious physical injury occurs. The anxiety caused by falling can result in loss of confidence and self imposed restrictions on activities, eventually resulting in admission to institutional care.

This book is based on an annual course …


Abstract Phenyl-1,2,3-triazoles containing (E)-vinyl halide were readily synthesized via a one-pot, three-component reaction of 3-(4- or 2-azidophenyl)acrylic acid, NXS(X=Cl, Br and I) and 1-alkynes in MeCN-H2O (9:1 v/v) catalyzed by LiOAc/CuI–sodium ascorbate system.


State responsibility — Claims — In general — Whether concessionaire has property interest in concession where grant of concession is invalid — Whether compensation due for assets destroyed by war.


Numerous studies on the adoption of health information technology (HIT) from various perspectives demands for a conceptual consolidation of knowledge across multiple levels and different landscapes in the field. Employing text mining and network analysis techniques, we conduct an exploratory investigation on the literature of HIT adoption from a socio-technical perspective. We explore the linkages among core concepts in prior research and construct an integrated theoretical framework of HIT adoption. Our theoretical framework adds to the socio-technical theory a new perspective that distinguishes between general considerations of technology adoption and issues specific to HIT adoption. We identify core and peripheral areas of prior research interest in the field and point out future research directions. The knowledge obtained is also beneficial for health care practitioners and policy-makers to improve the effectiveness in the adoption and use of HIT systems.


In this article the performance and experience of three large RPC systems in the running/future experiments are summarized: Belle, BaBar and BESIII.


This study was carried out to determine the appropriate weight (smolt) of hatcheryreared Rutilus frisii kutum (Kamenskiy, 1901) and a suitable salinity for releasing
fingerlings into the natural habitat. For this, important factors such as osmoregulatory hormones, level of serum osmotic pressure, Na+/K+ ATPase, blood ions, gill chloride cells activity and chloride cell size were investigated. In the study, 454 fingerling were allocated into four weight groups namely 1, 3, 5 and 7 g and exposed to three salinity treatments i.e. Caspian sea water (12-13 ppt), estuarine
water (7-9 ppt) and Freshwater (control, 0.3 ppt). Each trial was run with three replicates and the experiments were laid out in a randomized complete block design (RCBD). In order to determine the ionic/osmoregulation ability, the blood samples and tissue fixations were carried out during 0, 12, 24, 48, 144 and 336 hours after exposure in the different salinities. Plasma osmolarity was measured using
osmometer, blood Na+ and K+ concentrations were estimated by flame photometer, auto-analyzer (RA1000) was employed to measure the Mg2+ and Cl- concentration with colorimetric methods. On the other hand, blood cortisol and prolactin level were determined by RIA (radioimmunoassay) and a competitive ELISA method, respectively. Na+/K+-ATPase activity in homogenates of gills was studied through
phosphate released from ATP. Histological indicators including chloride cell perimeter and area were assessed using Biocom software and light microscope with digital camera. The results of osmolarity and ions measurement showed that 3, 5 and 7 g kutum (Rutilus frisii kutum) could maintain the osmolarity and ion concentrations and adapt to salinity of 7 and 13 ppt. However, the level of cortisol
and prolactin in 1 g kutum after 48 hours up to the end of the experiment showed significantly higher values compared to other weight groups (P<0.05). The size of chloride cells did not change in 1 g kutum in different salinities. However, in other groups, a significant increase of this perimeter was detected during the experiments (P<0.05). The Na+/K+ ATPase activities in 3, 5, and 7 g weight groups, under exposure to 7 and 13 ppt salinities, were seen to be higher than 1 g juvenile kutum and respective control level (P<0.05). In conclusion, the current research finding
indicated that ionic/osmoregulatory ability of juvenile kutum depends on their body weights. Despite, high ability of sea water adaptation in 3, 5 and 7 g kutum, 1 g fingerlings were not able to adapt themselves to the Caspian Sea and estuarine water as well as other groups. Therefore, they cannot be considered as the suitable weight
for the release process and net-culture in Caspian Sea water salinity.


We calculate gluon self-energy using quark energy projectors in a general quark-gluon plasma. By separating the quark field into a positiveand a negative-energy mode, the quark loop constructed with the same mode is always convergent, and the divergence appears only in the mixed loop with different modes and is medium independent. After removing the divergence in vacuum, we obtain the one-loop gluon self-energy at finite temperature, chemical potential and quarks mass without approximation. With the method of quark loop resummation, we calculate non-perturbatively the gluon Debye mass and thermodynamic potential. In the limit of small gluon momentum in comparison with temperature, chemical potential and quark mass, our calculation comes back to the known HTL/HDL results in literature.


The proliferation of power electronic based nonlinear loads and time varying devices causes harmonic pollution in industrial power system in recent years. The harmonic distortion can cause overheating and increased losses in the equipments used in distribution system and also interference with the communication systems. This paper presents a new soft computing technique based on an adaptive wavelet neural network (AWNN) for harmonic distortion measurement. Wavelet Neural Network (WNN) is a new technique recently proposed for harmonic distortion monitoring. In this work, Mexican hat wavelet has been selected for activation function in the hidden layer of the network. The validation of proposed AWNN is examined with feed forward back propagation network (FFBPN). The proposed method has been verified that the improved estimation accuracy and low computational time, when compared to the FFBPN


Affidavit In Any Fact by Sam Guinyard who witnessed a person running with a pistol in hand. Guinyard states that he saw the man near Patton Street and 10th Street, and then saw a policeman lying in the street. He later identified the man in a police lineup.


Recent attempts by Evolutionary Psychologists to explain the human decision process by proposing theories based on ecological adaptation have met with limited success. In particular, the difficulties associated with empirical testing have caused many critics to refer to these evolutionary theories as " just so stories" which are consistent with the historical development of mankind but that are not capable of falsification. More importantly, many of these evolutionary theories appear to be based on a modular theory of mind that implies a simplistic Darwinian inheritance process. In this important new book, geneticists Jablonska and Lamb argue that the gene centered Neo –Darwinism that has dominated biological thought for the last 50 years( the Mendel-Darwin Grand Synthesis) is being replaced a new model that envisions human evolution and environmental adaptation as the result of four interacting inheritance processes. Thus human decision behavior does not just reflect chance genetic (DNA) variations that happened to provide adaptive advantage. While the focus of this book is heredity, the authors stress the following:


Fatigue due to low-cycle tensile loading in plain concrete was examined under different conditions using the pressure-tension apparatus. A total of 22 wet or dry standard concrete cylinders (100 mm × 200 mm) were tested. By definition, low-cycle loading refers to the concept of multiple load cycles applied at high stress levels (i.e., a concrete structure subjected to seismic loading). Results suggest that concrete samples subjected to low-cycle tensile loading will fail after a relatively low number of cycles of loading and at a lower magnitude of stress compared to the maximum value applied during cyclic loading. Furthermore, non-destructive testing was employed in order to ascertain the extent of progressive damage inflicted by tensile loading in concrete specimens. It was found that ultrasonic pulse velocity is a viable technique for evaluating the damage consequential of loads applied to concrete, including that resultant from low levels of tensile stress (i.e., as low as 10% of its maximum tensile capacity). Additionally, finite element analysis was performed on a modeled version of the pressure-tension apparatus with a sample of concrete, which has yielded similar results to the experimental work.


The aim of this paper is to analyze the industrial buying behavior in order not only to improve the knowledge of buying industrial process carried by the organizations but also to identify the factors behind the level of participation in the buying decisions and the factors related with the degree of influence among the members of the buying center. Thus, we perform a survey of previous work on the relation between the variations of participation and the influence of the buying group, and the characteristics of purchase situation, the individuals and the organizational structure. Among conditions of purchase situation we consider those which most often appear in the prior research: novelty, product complexity, buying situation complexity, buying importance, time pressure and perceived risk associated to the purchase. With respect to individual characteristics, we include the personal stake and degree of experience. Finally, we consider the set of variables which characterize the company's organizational structure: work division, degree of formality of relations, decision-making centralization, standardization and configuration, as internal or anatomic structures, and size or dimension as factors of the specific environment. Furthermore, we test their explanatory power for a sample of Spanish industrial firms. LISREL statistical package is the tool used to verify the hypothesis proposed on the paper.


Total, soluble and microsomal fraction proteins were isolated from leaves of healthy and virus-infected cucumber and tomato plants, and separated by SDS-polyacrylamide gel electrophoresis. The analysis revealed the accumulation of a microsomal fraction protein in severely infected plants: cucumber with zucchini yellow mosaic virus (ZYMV) and tomato with cucumber mosaic virus (CMV). The proteins accumulated (MP 39) in the hosts when they showed severe disease symptoms exhibited the same electrophoretic mobility and had a molecular mass of approximately 39 kDa. The MP 39 was not revealed by concanavalin-A, and was present in the aqueous phase from Triton X-114 fractionation, indicating that the MP 39 is a peripheral membrane protein. Bidimensional electrophoretic analysis revealed the same characteristics for the protein accumulated in infected cucumber and tomato. Antibodies directly raised against virus particles failed to react with the MP 39, suggesting the accumulated protein is unrelated to any of the structural proteins of ZYMV and CMV, being probably a host encoded protein that accumulates in severely virus-infected plants. While activities of soluble and cell wall bound peroxidases were increased in infected plants, no peroxidase activity was found associated with MP 39. The data obtained in this work are a good base for subsequent studies on the role of the MP 39 in infected plants.


The paper deals with a mathematical model of switched reluctance motor, with stator of on induction motor. The parameters of this model were determined experimentally. The motor winding were supplied from different frequencies AC voltage source. Based on the measurements of current and voltage equivalent resistance and inductance of motor windings as a function of frequency were determined using the least squares method. The measurements for different rotation angle of the rotor were carried out. The measured resistance value was significantly higher than the value of the winding resistance because of "iron losses". The losses are modeled as the losses of a single turn wound on the rotor core, representing the eddy currents circuit. The losses are dependent on the angle of the rotor rotation relative to the stator. Based on the relationship between the equivalent inductance and resistance of the motor measured and specified of the model, the parameters were determined.


Aims: To investigate the relation of 1) S-IgA levels in saliva with tongue coating 2) S-IgA levels in saliva with oral malodour, in patients with health, gingivitis and chronic periodontitis. Materials and method: 90 systemically healthy subjects aged 18-60 years were included in this study. They were grouped into three groups after clinical examination. Each group comprised of 30 subjects. Group IHealthy subjects, Group II- Subjects with Gingivitis, Group III – Subjects with severe chronic periodontitis. Modified Gingival Index, Plaque Index and the Russel's Periodontal index were recorded for all subjects. Tongue coating was scored as per the scoring criteria described by Kojima et al, 1985. A simplification of the Organoleptic assessment scale by Rosenberg and McCulloch (1992) was used for grading oral malodour. 2ml of unstimulated saliva was collected from all 90 subjects into sterile ependoff tubes for estimation of secretory IgA levels using ELISA procedure. Results: This S-IgA level shows an inverse relationship with tongue coating and oral malodour as the disease activity progresses from gingivitis to severe chronic periodontitis Conclusions: There was a statistically significant inverse correlation seen between the tongue coating and SIgA levels in saliva in health, gingivitis and chronic severe periodontitis. 2) A statistically significant inverse relationship was noticed in the oral malodour and S-IgA levels in healthy subjects and patients with gingivitis and chronic severe periodontitis. Thus, S-IgA levels in unhealthy subjects may show potential in limiting periodontal disease activity and may prove to be a significant biomarker of disease alteration.


Gale,® part of Cengage Learning, has partnered with Peterson's to deliver the most comprehensive resource available to take users from the classroom into the workplace. Testing & Education Reference Center is a dynamically updated database that connects users to the most current information on colleges and universities — and adds a career module that guides people of all ages and experience to the career best for them.


The spillover effect of industrial innovation has always been a difficult problem for empirical analysis.Dietzenbacher(2000) established an empirical models of innovation spillovers based on the input-output table.The empirical analysis showed that the process innovation was the main form of innovation spillover in China,and the spillover effect was declining overall.In order to exert the spillover eddect,we should step up the RD investment of the traditional labor-intensive industries,such as the food industry,and increase the innovation investment of the producer service industry.


We focused our analysis on discontinuation syndrome, a frequent but unrecognised entity in psychiatric practice, which could be responsible for a great deal of misdiagnosis and treatment errors. If benzodiazepines and anticholinergics are well known for their potential of inducing discontinuation syndromes, there was less research regarding antidepressants and antipsychotics from this point of view. Theoretical data as well as clinical vignettes are presented here in an attempt to underline the necessity for inclusion of this syndrome in differential diagnosis and to show several ways to deal with it.


This article takes for example the Tujia assemble area -PoJiao village which has a quite intact minority language culture.It takes the anthropological view to analyze the reasons of country labor force transfer and its influence brought to the minority area country society development.The transfer has improved the minority country development like Pojiao country,however,it brings some unavoidable problems at the same time and influences the stable harmonious minority country society.


Objective To investigate the effect of N-4-hydroxyphenyl retinode (4-HPR) combined ultrasound on apoptosis of rabbit ear hypertrophic scar fibroblasts and Bax protein expression. Methods Set up four groups of the rabbit ear hypertrophic scar model,that is control group,4-HPR group,ultrasonic radiation group and 4-HPR combine ultrasonic radiation group. After rabbit ear scar formation,we used 4-HPR injection and ultrasound treatment. We observed Bax protein expression in dermal fibroblasts by immunohistochemical method,comparative studied the effect of 4-HPR combined ultrasound therapy on apoptotic activity of fibroblasts during the experimental treatment process of rabbit ear hypertrophic scars. Results Compared with the control group,Bax protein expression of fibroblasts increased in the 4-HPR and ultrasound combined irradiation in the rabbit ear hypertrophic scar tissue,and the difference was statistically significant (P 0. 05) . And its role showed as 4-HPR concentration-dependent and ultrasonic radiation intensity dependent. Conclusion 4-HPR and ultrasonic irradiation promoted the apoptosis of fibroblast in dermal layer of hypertrophic scar tissue through the Bax pathway,which plays a role of prevention and treatment for the rabbit ear hypertrophic scar.


I n the United States, the use of pharmacotherapies for treating substance use disorders is receiving increased attention. Evidence suggests that medications such as methadone and buprenorphine (also called agonist mediations) relate to positive outcomes in the treatment of opiate dependence, while naltrexone and disulfiram may improve outcomes when treating opiate dependence and cocaine dependence. Despite evidence of their effectiveness, the adoption of these therapies by treatment organizations has been slow. Research suggests that factors related to agencies' organizational context can affect whether medications are offered to patients. An understanding of such factors is critical in bridging the "research to practice gap" in the use of pharmacotherapies for substance use disorder treatment.


The thumb plays an important role in hand function. Daily tasks involving pinch, grip, grasp and precise handling are more easily accomplished with an opposable thumb, Loss of thumb diminish much the hand abilities and function.1 Soft tissue injuries of the hand frequently require flap coverage, either to preserve structures or even to facilitate later reconstruction.2 The absence of the thumb, whether due to failure of formation or loss from trauma, significantly impairs hand function.3,4 The goals of thumb reconstruction are sensate and non tender thumb tip, stability of thumb joints, adequate length to resist the forces of the fingers, correct posture and postioning of the thumb with a wide adductor space.5


This article analyses the basic ethnic groups of the Penza region and identifies the demographic processes taking place within each group. The author comes to a conclusion that these processes are determined by the features of the historical development and socioeconomic standing of the ethnic groups.


Asthma and rhinitis often coexist and share many clinical features. The extent of epithelial alteration in nasal inflammation is controversial. Cell-cell adhesion plays an important role in tissue morphogenesis and homeostasis and is mediated by the cadherin family. In human bronchial epithelial cells the authors have shown that tumour necrosis factor (TNF)-α induced a significant decrease of E-cadherin and β-catenin expression. The addition of dexamethasone inhibited this decrease. The aim of the present study was to investigate the effect of TNF-α and dexamethasone on the regulation of E-cadherin, γ-catenin and β-catenin in human nasal epithelial cells (HNEC). A primary culture of HNEC, obtained from human nasal turbinates after surgery, was used. The quantitative and qualitative modulation of E-cadherin, γ-catenin and β-catenin expression was assessed by Western blot and immunofluorescence analysis. In order to assess the TNF-α-induced activation of HNEC, interleukin-8 and RANTES (regulated on activation, normal T-cell expressed and secreted) release was assessed by enzyme-linked immunosorbent assay. The results showed that TNF-α induced, a decrease in γ-catenin and β-catenin expression, but had no effect on E-cadherin expression. Immunofluorescence showed that TNF-α induced cytoplasmic localisation of E-cadherin, γ-catenin and β-catenin. Dexamethasone inhibited the effect of TNF-α and induced a three-fold increase in E-cadherin expression. These results suggest that the difference in nasal and bronchial epithelial cohesion may be due to the differential effect of tumour necrosis factor-α and dexamethasone on E-cadherin expression.


Manipulation of adding sequences have been found to influence the reaction rate, thus made it easier to produced controllable Ni nanoparticles. Hot-injection approach shown capability to significantly reduce the production time of Ni nanoparticles compared to the conventional one-pot synthesis. With minor modification on conventional polyol method, narrow, monodispersed and highly yield spherical nickel (Ni) nanoparticles were successfully produced at synthesis temperature of 60°C. Three mixing methods were investigated to study its efficiency towards producing rapid and narrower size distribution of Ni nanoparticles. Reduction processes were proposed each of the method. As-synthesized Ni nanoparticles were characterized with Transmission Electron Microscopy (TEM), Scanning Transmission Electron Microscopy (STEM) and Fourier transform infrared spectroscopy (FTIR) to analyze the size, morphology and interaction of reactants. Fine particles size distribution revealed that when hydrazine was first heated, reaction rate improved tremendously.


Surface and electrochemical characteristics are analysed for Laser Peened Ti6Al4V in present study. X-ray diffraction studies disclose that peaks shifts and broadening of peaks took place after laser peening. The laser parameters will have effect in varying the material hardness and its gradual decrease in hardness is observed when measured from surface to depth profile. Microstructural changes are recognized during microscopic observation of cross-sectional laser peened samples. Mechanical and thermal surface damage with dimples and recast layer is observed for 1064 nm and 532 nm laser wavelengths respectively at same power density of 3 GW cm−2. These damages quantify the surface roughness variation between two laser wavelengths. SEM observation reveals the melted and distorted regions of the surface that would change the electrochemical properties after laser peening. Anodic potential shift has observed in both Open Circuit Potential (OCP) and Tafel Exploitation for samples with thermal damage which is not seen in samples with surface distortion. To analyse the effect of residual stress on electrochemical corrosion resistance, the samples are electro polished for 50 μm and electrochemical studies are analysed once again. A complete anodic shift compared to untreated sample is observed for all the peened samples.


The article discusses the possibility of integrating the traditionally opposed approaches of Agile and Kanban in the management of large manufacturing enterprises. The aim of the study is to develop a new algorithm for the implementation of lean production via formation of small work groups that operate based on Scrum methodology. Authors have classified famous approaches to lean manufacturing implementation, identified general patterns, and proposed a new integrated approach. The developed algorithm helps to launch lean production at a large enterprise in a most efficient way, quickly involve personnel in the change process, and identify change leaders. Agile frameworks in lean management support to get a specific result in a short time and make quick adjustments to scheduled plans.


There are many challenges that businesses have to overcome to satisfy their consumers or attract new customers. Therefore it is necessary to develop profiles to identify factors affecting current and future demand. This process requires an analysis of actual, reliable data from reliable, free-access sources. Lacking such information, it was necessary obtain data through studies carried out by companies themselves. We now have data reported by the National Institute of Statistics and Censuses and socioeconomic studies carried out by various national universities among others. Given that any interested person can access the socio-economic figures; it can be possible to optimize the use of resources at the national level, in particular in the Canton of Milagro in order to meet the financial objectives of the organization or design and implement new and innovative strategies to exploit opportunities in the market. The article concludes by presenting recommendations, product of the reading and analysis of the socio-economic figures, which may be considered on the basis of commercial criteria, identifying characteristics of the current consumer to thus satisfy their needs.


e17568Background: The increasing incidence of HPV associated oropharyngeal cancer has sparked interest in minimally invasive transoral surgery as a primary treatment modality. However, adequate sur...


When the existing intelligent video monitoring technology is applied to the detection personnel in the mine danger area, the false alarm signal will be generated when the mining lamp irradiates the danger area, there by reducing the detection accuracy. In order to solve this problem, this paper uses the fuzzy theory combined with the shape characteristics of the miner's lamp irradiation area to eliminate the light interference problem. The experimental results show that the proposed algorithm can effectively solve the problem of miner's lamp interference and detect the personnel intrusion behavior in the actual environment of coal mine and produce alarm signal in time.


In micro fluidic applications for chemical analysis and chemical reaction, plastic materials are getting substantial attracts. PMMA has been widely used for micro fluidic device application due to easy fabrication and low cost [1]. Some PMMA devices such as electrophoresis chips have been reported [2]. These devices reported so far were consisted of two parts, PMMA substrate having the microchannel and a flat substrate as the cover plate. Flat bottom and slanted sidewalls for easy removal was usually obtained. However some fluidic applications require parallel vertical sidewalls. In this paper, we studied hot embossing method realizing PMMA microchannel that has vertical sidewall.


This paper presents a modular system for the support of experiments and research in text classification. Usually the research process requires two general kinds of abilities. Firstly, to laboriously analyse the provided data, perform experiments and from the experiment results create materials for preparing a scientific paper such as tables or graphs. The second kind of task includes, for example, providing a creative discussion of the results. To help researchers and allow them to focus more on creative tasks, we provide a system which helps performing the laborious part of research. The system prepares datasets for experiments, automatically performs the experiments and from the results calculates the scores of Precision, Recall, F-score, Accuracy, Specificity and phi-coefficient. It also creates tables in the LaTex format containing all the results and it draws graphs depicting and informatively comparing each group of results.


WH2 domains are multifunctional regulators of actin assembly that can either sequester G‐actin or allow polarized barbed end growth. They all bind similarly to a hydrophobic pocket at the barbed face of actin. Depending on their electrostatic environment, WH2 domains can nucleate actin assembly by facilitating the formation of prenuclei dimers along the canonical spontaneous assembly pathway. They also modulate filament barbed end dynamics in a versatile fashion, acting either as barbed end cappers or assisting barbed end growth like profilin or uncapping barbed ends and potentially mediating processive elongation like formins when they are dimerized. Tandem repeats of WH2 domains can sever filaments and either remain bound to created barbed ends like gelsolin, or strip off an ADP‐actin subunit from the severed polymer end, depending on their relative affinity for terminal ADP‐F‐actin or ADP‐G‐actin. In summary, WH2 domains recapitulate all known elementary regulatory functions so far found in individual actin‐binding proteins. By combining different discrete sets of these multifunctional properties, they acquire specific functions in various actin‐based processes, and participate in activities as diverse as filament branching, filopodia extension, or actin remodeling in ciliogenesis and asymmetric meiotic division. They also integrate these functions with other actin‐binding motifs present either in the same protein or in a complex with another protein, expanding the range of complexity in actin regulation. The details of their molecular mechanisms and the underlying structural basis provide exciting avenues in actin research. © 2013 Wiley Periodicals, Inc.


We accept that a few parts of information science and business examination have been around for a long time, but there are critical new inquiries and openings made by the accessibility of huge information and significant progressions in machine knowledge.


This study deals with the convergence and divergence issue in terms of the possible difference in the knowledge-sourcing behaviour of latecomer and incumbent firms. Consequently, empirical analysis using the patent citation data shows that no significant difference exists in the knowledge-sourcing behaviour of the incumbents and latecomers in long-cycle time-based sectors, particularly in terms of whether each type of firm relies more or less on 'recent' and 'scientific' knowledge. By contrast, a significant difference is observed in the short-cycle technology-based sectors, such that the latecomer firms tend to rely more on 'recent' and 'scientific' knowledge than the incumbents. Thus, the findings suggest that the answer to the question of whether convergence or divergence exists in knowledge sourcing is that it depends on the knowledge regime of the sectors, specifically on the cycle time of the technologies of sectors. This finding is consistent with the reasoning that the latecomer firms can afford to rely only on recent technologies in short-cycle sectors in which technologies tend to change quickly or become obsolete; latecomer firms are also keen on their knowledge sourcing to broadly search not only into technological knowledge (patents) but also into scientific knowledge (articles) in short-cycle sectors with rapid change of technologies.


Abstract:Research on second language Spanish encompasses a sophisticated and broad-reaching body of work. Nevertheless, there is a bias in this literature toward English-speaking learners. The implication of this bias is that our search for universal trends of acquisition is undermined by an inability to distinguish between challenges that are specific to English-speaking learners and those that apply across learner populations. The goal of this essay is to demonstrate the value of extending the scope of second language Spanish research to include diverse first language populations and to illustrate new insights that might be gleaned through a presentation of recent research on Korean-speaking learners.


Machine learning problems can be addressed by a variety of methods that span a wide range of degrees of flexibility and robustness. In the process of building a model for data, flexibility and robustness are desirable but often conflicting goals. On one side of the spectrum, parametric methods are very robust, in the sense that they are resilient to noise and are not generally misled by spurious regularities, which may be present in the data only by accident. However, their expressive capacity is limited. On the other side, non-parametric methods are very flexible and can in principle learn arbitrarily complex patterns when sufficient amounts of data are available for induction. However, as a result of this high flexibility, they are also more prone to overfitting. In practice, selecting the optimal method to address a specific learning task involves attaining the appropriate balance between flexibility and robustness. There are some learning problems for which this balance cannot be attained using standard parametric or purely non-parametric approaches in isolation. Semi-parametric methods include both parametric and non-parametric components in the models assumed. The parametric part provides a robust description of some of the patterns in the data. The non-parametric component endows the model with the flexibility necessary to capture additional complex patterns. In this thesis, we analyze several problems in which semi-parametric methods provide accurate models for the data. The first one is the modeling of financial time series. The trends in these series are described by parametric models. The density of the innovations is directly learned from the data in a non-parametric manner. To improve the quality of the approximation, the estimation of the density of the innovations is performed in a transformed space, where the density of the transformed data is close to a Gaussian. A second problem involves developing semi-parametric models to describe arbitrary non-linear dependencies between two random variables. Bivariate Archimedean copulas are re-parameterized in terms of a unidimensional latent function that can be readily approximated using a basis of natural cubic splines. These splines are especially well suited to model the asymptotic tail dependence of the data. In some learning problems even simple parametric methods are not sufficiently robust to provide accurate descriptions for the data. This investigation also addresses the specific question of how to improve the robustness of linear models by assuming sparsity in the model coefficients. In a Bayesian approach, sparsity can be favored by using specific priors, such as the spike and slab distribution. The advantage of the spike and slab prior is its superior selective shrinkage capacity: Some coefficients (those whose posterior has a large contribution from the spike) are forced to be small, while others (those in which the slab is the predominant contribution to the posterior) are not regularized. In this thesis, linear models with spike and slab priors are used to address problems with a high-dimensional feature space and small number of available training instances. Approximate inference is implemented using Expectation propagation (EP). For the sparse linear regression model, EP is a computationally efficient alternative to MCMC methods, which are asymptotically exact, but often require lengthy computations to converge. Another contribution is the design of a sparse Bayesian classifier for classification problems in which prior information about feature dependencies is available. Finally, a sparse linear model that makes use of a hierarchical spike and slab prior is applied to the problem of identifying transcriptional regulators from gene expression time series. The semi-parametric methods and the sparse linear models analyzed in this thesis represent configurations of flexibility and robustness that cannot be attained by either standard parametric methods or by fully non-parametric approaches alone. Therefore, the proposed methods fill in some of the gaps left by these standard learning paradigms in the flexibility-robustness spectrum.


Vocational education and training (VET in Australia, PVET in Europe), as a unified endeavour, has to balance the comparative wealth of the peak universities with the needs of the community and young people for the employabilty that VET can provide. VET needs to promote its scope and strengths collectively and individually, and we analyse some of them. The subtext is that the paper highlights the features of leading institutions on which institutions can model their future development. There is no one unewuivocal model of course, so this paper senitises leaders to salient issues.


After implementation of the Real Plan in July 1994 by the Brazilian government, the industrial chicken was established in consumer preference causing change in their spending habits. This change was attributed in great part due to their affordability to the consumer. This article aims to analyze the price transmission elasticity of poultry in the state of Sao Paulo market and identify which market level focuses on the greatest power of pricing, either at the producer level, wholesale and retail. By studying Sao Paulo's poultry market, we intend to provide information to support decision making by managers of the production chain. Furthermore, Sao Paulo is the largest poultry consumer market in the country. Therefore, it is used in the treatment of poultry price data at the producer level, wholesale and retail the econometric model of Vector Autoregressive (VAR). The results found by analyzing the variance decomposition of forecast errors demonstrate that the producer has a high power setting of prices of poultry in the Sao Paulo's market, having direct influence on the formation of prices both at wholesale as well as retail.


We developed a switchable terahertz and multi-terahertz spectroscopy system to investigate the optical and electrical properties of a light-driven three-dimensional Dirac semimetal, Cd$_{3}As_{2}$. The femtosecond multi-terahertz probe pulse enabled us to track the ultrafast change of the broadband response functions in the 12-45 THz frequency region. We observed a large reduction of the refractive index after pulsed mid-infrared excitation, which is attributed to a combination of a light-induced shift in the plasma frequency and a long scattering time specific to Dirac semimetals. Upon changing the pump light to a narrowband multi-terahertz pulse which lies inside the probed frequency band, we observed strong stimulated Rayleigh scattering characterized by an absorption peak and an emission peak sandwiching the driving frequency. Microscopic calculations showed that this phenomenon originates from optical transitions among the light-dressed energy bands, called the Floquet-Bloch bands, which are enhanced by the collective plasma mode responsible for the large reduction of the refractive index. We propose a possible route to slow light generation based on the large stimulated Rayleigh scattering in a metallic material at room temperature. We also transformed the driving multi-terahertz pulses into circularly polarized ones, to study the light-induced anomalous Hall conductivity through the terahertz polarization rotation. Comparison of experiment and theory showed that the observed anomalous Hall conductivity mainly originates from the circular photogalvanic effect allowed by the terahertz electric field, and that the theoretically anticipated Floquet-Weyl semimetal plays a minor role under the present experimental conditions. We also revealed that the isospin degree of freedom in Dirac semimetals can be injected by circularly polarized light and detected through the anomalous Hall conductivity after photoexcitation. These studies elucidate both the interband and intraband physics in the massless Dirac fermions.


TiO2:ZnO nanostructures thin films have been fabricated on glass substrates via sol-gel spin-coating technique for deposition of TiO2 seed layer and solution-immersion method for growth of ZnO nanostructures. The layer of TiO2 were annealed at various temperatures ranging from 350 to 500°C for 2 hours to examine the effect of annealing TiO2 seed on the growth of ZnO nanostructures. The surface topography of TiO2 seed layer were investigated by Atomic Force Microscope (AFM) and surface morphology of TiO2: ZnO nanostructures thin films were observed by Field Emission Scanning Electron Microscope (FESEM). The optical properties of TiO2 seed layer and TiO2: ZnO nanostructures thin films as a function of seed annealing were determined by Ultraviolet-Visible (UV-Vis) spectrophotometer. As the annealing temperature of the seed layer increase to 450°C, the surface of the seed layer improved which causes the diameter size reduction of ZnO nanostructures and enhance the UV absorption properties and optical transmittance.


OBSTRUCTIVE appendicitis is the name given to that type of appendicitis in which obstruction of the lumen is associated with distension of the coats of the viscus, distal to the obstruction, by exudate which may be mucus or mucopus,and if the latter may be mixed with faxal material. An inflammatory attack is probably the primary cause, the obstruction being secondary. The blockage of the lumen is most commonly due to a stercolith or scybalous mass, but other causes are recognized, as will be pointed out later. The distension of the coats leads to nutritional changes which ultimately result in necrosis of the distended portion. In 1914 Wilkie called attention to the pathological picture and in some experimental work showed the gravity of the condition. He segregated a loop of the lower ileum and reestablished the continuity of the small bowel. The segregated loop became distended, the wall necrosed: and infection of the peritoneal cavity resulted. Wilkie gave the two common causes of obstructive appendicitis as ( I ) fibrous stenosis, (2) acute kinking. He found that a much more rapid necrosis set in if fEcal material was milked from the caecum into the segregated loop before this was finally isolated. He concluded that " the attack of acute obstruction is probably excited by access of faecal material t : the distal part of the appendix beyond the kink . Behan (I~zI), working along much the same lines in rabbits, but directly on the appendix itself, came to the conclusion that partial occlusion in rabbits does not cause appendicitis even though faxal material collects in the part distal to the partial occlusion. It is thirty years since Wilkie's paper was published. In this time it has been possible to collect and analyse cases of obstructive appendicitis, to compare them with other types of the disease, to discuss the incidence and the causes, and to consider some problems which arise out of a study of the subject. In considering the incidence an analysis of two lots of cases, one of 150 the other of 357, has been made. In the former there were rg cases, in the latter 51. We may conclude that the percentage of cases of obstructive appendicitis (only acute disease is being considered) is somewhere about 13 to 14 per cent. This percentage of cases is only approximate, since it deals with cases found at operation where abscess formation has not resulted. Abscess formation is dueto other causes than obstructive appendicitis, so that where an abscess has formed it may be impossible to say whether it is due to obstructive appendicitis, perforation, or lymphatic spread. The error must be very small. As to the origin of the obstruction an analysis of 38 cases can be given, a consecutive series covering a period of eleven years. The following table is the result :-


Abstract : A mixture of physiologically compatible compounds with the properties of inhibiting alkylation reactions, providing metabolic support to the tissue and capable of preventing oxidative damage is being developed and tested for its effectiveness against mustard induced toxicity. A partial preventive effect of such a formulation using mouse skin as an animal model has been demonstrated for the first time.


Ontology matching is crucial to data integration for across-silo data sharing and has been mainly addressed with heuristic and machine learning (ML) methods. While heuristic methods are often inflexible and hard to extend to new domains, ML methods rely on substantial and hard to obtain amounts of labeled training data. To overcome these limitations, we propose
 VersaMatch
 , a flexible, weakly-supervised ontology matching system. VersaMatch employs various weak supervision sources, such as heuristic rules, pattern matching, and external knowledge bases, to produce labels from a large amount of unlabeled data for training a discriminative ML model. For prediction, VersaMatch develops a novel ensemble model combining the weak supervision sources with the discriminative model to support generalization while retaining a high precision. Our ensemble method boosts end model performance by 4 points compared to a traditional weak-supervision baseline. In addition, compared to state-of-the-art ontology matchers, VersaMatch achieves an overall 4-point performance improvement in F1 score across 26 ontology combinations from different domains. For recently released, in-the-wild datasets, VersaMatch beats the next best matchers by 9 points in F1. Furthermore, its core weak-supervision logic can easily be improved by adding more knowledge sources and collecting more unlabeled data for training.


The concept of self-powered wearable electronic
system has been emerging. Such a system consists of three units: an
intelligent end-user electronic device for exporting functions, an
energy generation/conversion device responsible for
harvesting/scavenging renewable energy, and additionally an energy
storage device to ensure non-intermittent operation. The three
units should be matched up in terms of energy and power, which
demands substantial efforts in research for advancing all the
components - the power consumptions of the electronics need to be
reduced, the efficiencies of the energy scavenging devices ought to
be improved, and the capacities of the energy storage devices are
desired to be enhanced. An additional requirement is that the three
units should all be made "human-friendly", namely lightweight,
flexible and wearable. This necessitates the fabrication of all to
be compatible with the unconventional substrates, such as papers
and plastics. Along the way to these goals, tremendous
opportunities and challenges with regards to materials and device
designs are present. This thesis focuses on the development of
mechanically flexible thin-film materials for electrochemical
devices, towards the achievement of self-powered wearable
electronic systems. Initiated chemical vapor deposition (iCVD) and
oxidative chemical vapor deposition (oCVD), which are
non-destructive to fragile substrates, have been employed for the
synthesis of the polymeric thin films. As an effort to enhance the
functional end-users, pinhole-free ionic liquid gels with thickness
down to 20 nm have been prepared for the first time via iCVD. They
show great promise as soft gate insulators for low-power high-speed
thin film transistors, which are central to a variety of wearable
electronics. To improve the energy storage unit, supercapacitors, a
promising energy storage device for low-power devices, have been
vapor-printed via oCVD onto flexible low-cost substrates, papers
and nylon membranes. Additionally, an ultrathin gel electrolyte
coating has been developed to boost the performance stability of
polymeric capacitive materials.


S7 type transformer and previous products due to loss is very high,has published by the national successively eliminated,to stop its production and marketing;Application of energy saving transformer,S11 with considerable energy saving potential.Technical personnel from S7 type and S11 type transformer loss and the investment capital is recovered a comparative analysis of the two aspects,and puts forward a kind of method of evaluation transformer efficiency.Through some station in type transformer production for S11 S7 replacement type transformer application effect,can see that eliminated energy-intensive transformer,can give society and the enterprise economic benefits brought considerable.


This research was aimed to determine the forms of errors and causes of errors that made
by the students of class VIII SMP Negeri 4 Lingsar in the academic year 2017/2018 in
solving algebraic factorization problems. The data were taken from the algebra
factorization material test results and the result of interview with the students. The type of
this research was quantitative descriptive research. The population in this research were
all class VIII SMP Negeri 4 Lingsar in the academic year 2017/2018 which amounts to
133 students. The sampling technique used was cluster sampling and taken each of 10
students from each rank of student ability. The data analysis technique that used in this
research was grouping error presented by Hadar. Based on the analysis of students
answers showed that the dominant error performed on the high ability students were a
unverified solution of 70.00% and misinterpreted language of 60.00%. On the medium
ability students, the dominant error were unverified solution of 80.00%. While on the low
ability students, the dominant error were a logically invalid inference of 100.00%. From
the interview results obtained the cause of students making mistakes in solving the
problems of algebra factorization. On the high ability students were the cause of the
students do not write down what were known and asked from the problem, not understand
the language change from the problem to become the language of mathematics and less
thorough in conducting operations count. On the medium ability students were the cause
of the student do not write down what were known and asked from the problem, less
thorough in performing the counting operation and has not mastered the prerequisite
materials. While on the law ability students were the cause of the students do no write
down what were known and asked from the problem, do not understand the intent of the
problem, less thorough reading of the problem so wrong in rewriting the data from the
problem and have not mastered the prerequisite materials.


Signal sparse representation has attracted much attention in a wide range of application fields. A central aim of signal sparse representation is to find a sparse solution with the fewest nonzero entries from an underdetermined linear system, which leads to various optimization problems. In this paper, we propose an Adaptive Gradient Projection (AGP) algorithm to solve the piecewise convex optimization in signal sparse representation. To find a sparser solution, AGP provides an adaptive stepsize to move the iteration solution out of the attraction basin of a suboptimal sparse solution and enter the attraction basin of a sparser solution. Theoretical analyses are used to show its fast convergence property. The experimental results of real-world applications in compressed spectrum sensing show that AGP outperforms the traditional detection algorithms in low signal-to-noise-ratio environments.


Conservation efforts require detailed knowledge of a species' habitat use and movements about the landscape. We radio-tracked sympatric congeners, the Copperbelly Water Snake (Nerodia erythrogaster neglecta) and the Northern Water Snake (Nerodia sipedon sipedon) in northwestern Ohio and southern Michigan, USA, to investigate differences in the use of wetland and upland habitats between species.Nerodia erythrogaster neglecta used twice as many wetlands (4.1±0.4) asN. s. sipedon (2.1±0.3), moved between these wetlands three times more often (9.1±1.9 times) thanN. s. sipedon (2.8±1.0 times), and moved to small wetlands seven times more often (3.6±0.7 times) thanN. s. sipedon (0.5±0.3 times). Nearly 30% ofN. e. neglecta locations were in uplands, sometimes over 100 m from the nearest wetland. Less than 3% ofN. s. sipedon locations were in upland habitats, and all locations were <30 m from wetlands. We simulated the impact of small wetland loss and demonstrated thatN. e. neglecta would need to move longer than normal distances when traveling between wetlands after small wetlands are lost, whileN. s. sipedon would not. The northernmost populations ofN. e. neglecta are listed as federally threatened and state endangered in Ohio, Michigan, and Indiana;N. s. sipedon remains abundant in this region. Historic and current wetland losses in the midwestern United States may have severely impactedN. e. neglecta populations due to this species' high vagility and use of numerous wetlands. Protection and restoration of wetland landscapes are critical for the long-term persistence of many wetland-associated species, species, includingN. e. neglecta.