Several observational studies have demonstrated an association between use of selective serotonin reuptake inhibitors (SSRIs) and upper gastrointestinal bleeding (JW Nov 19 1999). The presumed mechanism is depletion of serotonin from platelets, resulting in impaired platelet function.

In this …


The banking sector in the Common Monetary Area (CMA) of southern Africa is highly concentrated. Accordingly there has been some debate as to what the impact of high concentration levels might be on the welfare of consumers of retail banking products. In this paper a structure-conduct analysis is carried out to assess whether the level of concentration influences the pricing of retail banking products and what the welfare impact might be . Findings herein suggest that the pricing of retail banking products in the CMA fits with the structureconductperformance framework. Policy implications imply a need for greater competition and regulatory reform to reduce welfare costs.


The industrial processes risk assessment is based on use of diverse qualitative and quantitative methods. Within the quantitative methods especially statistical methods are able to be used for classification of statistical data, relative counts, probability, correlation and contingency so much important for investigation of mutual relations of the risk and consequences of industrial accidents. In application with other mathematic methods they allow to assess the risk based on the risks estimations and their impacts. The paper presents starting points for the above mentioned investigation.


Data mining is performed on to the large repository of the data for generating the relevant data. In current time there are large number of applications where large repository can be used to store large generated data from itself. Like Facebook, Whatsapp. This much large repository of data will be very difficult to store and then later on process to extract useful data. Various data mining techniques are used for this purposes. But the data mining result generating ability will be reduced if the data is imbalanced. Because imbalanced data will be having imbalanced classes. One class can have substantial amount of data and other class can have very few data items. Various researchers are researching on this for having balancing of the data. So that result generation can be optimized. In current review paper is to study different techniques used for balancing of the imbalance classes.


In the present digital era, more data are generated and collected than ever before. But, this huge amount of data is of no use until it is converted into some useful information. This huge amount of data, coming from a number of sources in various data formats and having more complexity, is called big data. To convert the big data into meaningful information, the authors use different analytical approaches. Information extracted, after applying big data analytics methods over big data, can be used in business decision making, fraud detection, healthcare services, education sector, machine learning, extreme personalization, etc. This chapter presents the basics of big data and big data analytics. Big data analysts face many challenges in storing, managing, and analyzing big data. This chapter provides details of challenges in all mentioned dimensions. Furthermore, recent trends of big data analytics and future directions for big data researchers are also described.


The edge-seal creates a thermal bridge at the perimete the IGU making this an area of increased thermal stress, h l Engineering, University of Waterloo, Ontario, Canada. THIS PREPRINT IS FOR DISCUSSION PURPOSES ONLY, FOR INCLUSION IN ASHRAE TRANSACTIONS 1998, V. 104, Pt. 1. Not to be reprinted in whole or in part without written permission of the American Society of Heating, Refrigerating and Air-Conditioning Engineers, Inc., 1791 Tullie Circle, NE, Atlanta, GA 30329. Opinions, findings, conclusions, or recommendations expressed in this paper are those of the author(s) and do not necessarily reflect the views of ASHRAE. Written questions and comments regarding this paper should be received at ASHRAE no later than February 6, 1998. A Simplified Numerical Method for digital form is not permitted without ASHRAE's prior written permission. 19951) do not account for fill gas convection. Therefore, they cannot be used to determine the minimum indoor pane temperapTp = anTn + asTs + aeTe + awTw (1) ce the d— in. is tle


It is quite common for networks emerging nowadays to have labels or textual contents on the nodes. On such networks, we study the problem of top-k nearest keyword (k-NK) search. In a network G modeled as an undirected graph, each node is attached with zero or more keywords, and each edge is assigned with a weight measuring its length. Given a query node q in G and a keyword λ, a k-NK query seeks k nodes which contain λ and are nearest to q. k-NK is not only useful as a stand-alone query but also as a building block for tackling complex graph pattern matching problems.

The key to an accurate k-NK result is a precise shortest distance estimation in a graph. Based on the latest distance oracle technique, we build a shortest path tree for a distance oracle and use the tree distance as a more accurate estimation. With such representation, the original k-NK query on a graph can be reduced to answering the query on a set of trees and then assembling the results obtained from the trees. We propose two efficient algorithms to report the exact k-NK result on a tree. One is query time optimized for a scenario when a small number of result nodes are of interest to users. The other handles k-NK queries for an arbitrarily large k efficiently. In obtaining a k-NK result on a graph from that on trees, a global storage technique is proposed to further reduce the index size and the query time. Extensive experimental results conform with our theoretical findings, and demonstrate the effectiveness and efficiency of our k-NK algorithms on large real graphs.


The nearly complete amino acid sequence obtained for murine calcyclin from Ehrlich ascites tumor cells reveals a very strong similarity with the rat and human sequences previously deduced from corresponding cDNA clones. While mouse and rat calcyclins are identical, the human protein shows at three positions a conservative amino acid replacement. Using a mouse calcyclin affinity matrix, two proteins with molecular masses of about 36 kDa have been purified from Ehrlich ascites tumor cells. The interaction between these two proteins and the immobilized calcyclin is strictly Ca2(+)-dependent. Immunological criteria and partial sequence data identify the two calcyclin-binding proteins as the phospholipid-binding protein annexin II (p36) and the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase. These observations suggest that calcyclin may exert its physiological function by a Ca2(+)-dependent interaction with cellular targets, e.g. annexin II or glyceraldehyde-3-phosphate dehydrogenase.


I. Sterile Technique Scrubbing Donning a Surgical Gown Donning Surgical Gloves Final Gown Tie Disrobing II. Skin Skin Biopsy Shave Biopsy Punch Biopsy Elliptical Biopsy/Excision Suturing Instrument Tie Buried Suture Dermal Buried Suture Running Suture vs. Interrupted Suture Staples Two handed Surgical Tie (Square Knot) Cyst Removal Incision and Drainage of Abscesses Removal of Ingrown Nail III. Head and Neck Ear Wax Removal Removal of a Foreign Body from Eye Conjunctival Removal of a Foreign Body from the Eye Corneal Removal of a Foreign Body from the Ear Removal of a Foreign Body from the Nose Nasogastric Insertion Orogastric Insertion Endotracheal Intubation IV. Chest and Lungs Central Lines (Venous Access Devices) Subclavian Central Line Placement Jugular Central Line Placement Femoral Central Line Placement Swan-Ganz (Pulmonary Artery) Catheter Placement Chest Tube Placement Thoracentesis Rapid Reduction of Tension Pneumothorax (Needle Decompresion) V. Heart and Peripheral Vasculature Electrocardiogram Pericardiocentesis Stress Testing Treadmill Pharmacological Venipuncture Femoral Venous Access Starting an IV Aterial Puncture Radial Artery Femoral Artery Arterial Line Placement Radial Artery Femoral Artery Blood Pressure Measurement Orthostatic Blood Pressure (Tilt Test) Doppler Blood Pressure Blood Culture Glucose Monitoring VI. Abdomen Paracentesis VII. Back Lumbar Puncture Epidural and Spinal Block VIII. Breast Breast Biopsy Fine Needle Aspiration IX. Female Genitourinary Pap Smear Conventional Thin Wet Prep Whiff Test KOH Slide Testing for pH Collection of GC and Chlamydia Cultures Herpes Culture Colposcopy Cryotherapy Loop Electrosurgical Excision Procedure (LEEP) Urinary Catheter Insertion Urinalysis Fecal Occult Blood Test Contraception Intrauterine Device (IUD) Placement IUD Removal Cervical Caps Diaphragm Placement X. Male Genitourinary Reduction of Testicular Torsion Inguinal Hernia Reduction Foley Catheter Insertion Collection of GC and Chlamydia Cultures XI. Musculoskeletal Arthrocentesis Shoulder Reduction Bone Marrow Aspiration and Biopsy XII. Nerves Electroencephalogram (EEG) Electromyography (EMG) Nerve Condition Studies (NCS) XIII. The Pregnant Patient Fundal Height Measurement Doppler Placement for Assessing Fetal Heart Sounds Amniotic Fluid Fern (Arborization) Test Internal Fetal Scalp Monitoring Intrauterine Pressure Catheter (IUPC) Placement XIV. Infants and Children Giving Injections Intramuscular Injection Subcutaneous (SQ) Injection Rectal Temperature Throat Swab Heelstick Intraosseous Infusion Lumbar Puncture in Infants and Small Children Umbilical Vein Cathetization Nursemaid's Elbow Reduction Male Circumcision Mogan Gomco Clamp Plastibell Apprendices


Abstract This study examines whether investors are concerned about textual geographic information in annual reports. Based on a sample of China's listed firms, we report the following findings: First, the more low marketisation districts (LMDs) appear in the annual reports, the higher the market return will be. Second, the result is more pronounced in non-state companies. Third, the frequency of LMDs is positively related with Tobin Q and CEO's compensation. Fourth, we are unable to detect any relation between the frequency of high marketisation districts (HMDs) and firm characteristics including short term market reaction, Tobin Q and CEO's compensation. Lastly, frequencies of both LMDs and HMDs are positively related with corporate innovation measured by patents. Taken together, the results show that a company can succeed in a developing area by filling the void of infrastructure. The strategy of expanding business in developing areas does not impair long term innovative activities.


The history of coastal settlement in Peru beginning ca. 12)000 years ago provides insight into maritime adaptations and regional specialization. we document the Late Paleoindian to Archaic occupational history along the Osmore River coastalplain near 110 with 95 radiocarbon dates from eight sites. Site distribution suggests that settlement shifted linearly along the coast)possibly in relation to the productivity of coastal springs. Marine ftods) raw materials) and freshwater were sufficient to sustain coastalftragers ftr over 12 millennia. Despite climatic changes at the end of the Pleistocene and during the Middle Holocene) we ftund no evidenceftr a hiatus in coastal occupation) in contrast toparts of highland northern Chile and areas of coastal Peru ftr the same time period. Coastal abandonment was a localized phenomenon rather than one that occurred acrossvast areas of the South Central Andean littoral. Our finds suggest that regional adaptation to specifichabitats began with initial colonization and endured through time.


Risk assessment is essential for managing risks and developing mitigation efforts related to debris flow hazards. The results of debris-flow risk assessments can be used as a scientific basis for planning regional economy, formulating national land use policies, selecting project sites, monitoring and controlling disasters and developing environmental conservation measures. Therefore, developing and applying effective methodologies for risk assessment becomes imperative. Risk assessment mainly involves establishing an index system and developing related methodologies. Disagreements exist among scientists on these two aspects. By summarizing previous achievements in risk assessment, this paper mainly discussed the theory, index and methodologies as well as future trends in risk assessment of debris-flow hazards. New fields of risk assessment on debris-flow hazards are recommended. A case study based on geographical information system (GIS) is given. In the past several decades, the assessment of debris flow risks has undergone several stages, namely from qualitative assessment to semi-quantitative assessment, from which to quantitative assessment, and various assessment methods have been advanced. The index system proposed by the authors in this paper is based on the hazard and vulnerability analysis, with the analysis of the expected loss as its core element. The hazard of debris flows, and the vulnerability and the expected loss thereof are the three primary parameters and form an index system of the risk assessment concerning debris flows. The proposed methodologies have been used to assess debris-flow hazards occurring in the Jinsha River Basin, China. The results demonstrate that debris-flow hazards can be assessed successfully through systematic assessment methods, and the adoption of new technologies, such as GIS and remote sensing, can improve the accuracy and efficiency of the risk assessment of debris-flow hazards.


In summer 2014, Southern Utah University's field camp visited five national parks and forests to study five different tectonic settings in five weeks. These included: thick-skinned contraction of the Laramide Orogeny at Capitol Reef National Park; normal faulting due to salt tectonics of the Paradox Formation at Arches National Park; thin-skinned folding and thrusting of the Sevier Orogeny at Fish Lake National Forest and Kolob Canyon of Zion National Park; foreland sedimentary transitions in the Book's Cliffs areas of Utah; thrusting and conjugate fracture development due to the gravitational collapse of the Marysvale volcanic field at Bryce Canyon National Park; and a metamorphic core complex at Great Basin National Park and Hendry's Creek in the Northern Snake Range of Nevada. This article provides a brief summary and photographic tour of the students' experiences studying each tectonic environment, and it highlights wonderful geological features exposed in our national parks.


This paper attempts to assess the real-world crashworthiness performance of the various child restraint systems covered by FMVSS 213 and motor-vehicle safety belts. The analysis is based on a sample of 103 cases of children who sustained injuries in motor vehicle crashes and were admitted to Children's National Medical Center in Washington D.C., a level 1 trauma center. Although the study is still under way, the preliminary findings, which are presented here, suggest a number of important directions for future study and analysis.


We consider the task of comparing fuzzy estimates of the execution parameters of genetic algorithms implemented at GPU (graphics processing unit' GPU) and CPU (central processing unit) architectures. Fuzzy estimates are calculated based on the averaged dependencies of the genetic algorithms running time at GPU and CPU architectures from the number of individuals in the populations processed by the algorithm. The analysis of the averaged dependences of the genetic algorithms running time at GPU and CPU-architectures showed that it is possible to process 10'000 chromosomes at GPU-architecture or 5'000 chromosomes at CPUarchitecture by genetic algorithm in approximately 2'500 ms. The following is correct for the cases under consideration: "Genetic algorithms (GA) are performed in approximately 2, 500 ms (on average), " and a sections of fuzzy sets, with a = 0.5, correspond to the intervals [2, 000.2399] for GA performed at the GPU-architecture, and [1, 400.1799] for GA performed at the CPU-architecture. Thereby, it can be said that in this case, the actual execution time of the algorithm at the GPU architecture deviates in a lesser extent from the average value than at the CPU.


Text Documents have high dimensions and processing knowledge from such huge magnitude of data is cumbersome. High dimensionality has inherent noise and sparsity. Dimension reduction is a preprocessing step in Text Mining which transforms data sets into more compact form and eliminates redundancy. Many statistical techniques like Principal Component Analysis (PCA), Independent Component Analysis (ICA) and their variants are available but these are incapable to check semantic information. Semantical techniques like Latent Semantic Analysis (LSA) help to find the semantic relationship but have computation limitation. This paper focuses on study and comparative analysis of dimension reduction techniques. The proposed hybrid method combines the success of statistical approach, semantic approach and then checks the extracted features with WordNet dictionary. This approach will help to reduce the dimensions and fulfill the purpose of semantic check.


Objective To explore the effects of Octogen(HMX)on peripheral nerve conduction velocity of workers.Methods 76 HMX\|exposed workers and 38 healthy workers not exposed to HMX and any other neuro\|toxic substances were selected as exposure and control group respectively.Motor nerve conduction velocity(MCV),sensory nerve conduction velocity(SCV)and motor latency of median nerve,ulnar nerve and common peroneal nerve were measured respectively by standard method.HMX concentration was also measured in the air of workplace,and different HMX concentrations and exposure time were compared.Results Motor latency at distal end of common peroneal nerve in exposure group was significantly prolonged,while SCV at proximal end of median nerve was significantly decelerated.Compared with the lower concentration exposure group,sensory latency at distal end of median nerve and ulnar nerve in higher concentration group was significantly prolonged.In the group with over 20 years of exposure,MCVs of median nerve,ulnar nerve and common peroneal nerve,as well as SCV of median nerve were significantly decelerated.In exposure group,abnormal rate of MCV of common peroneal nerve was significantly higher than that in control group.Conclusions It suggests that HMX might have significant effects on nerve conduction velocity in lower limbs.The mechanism was unknown and further study needs to be done to explore whether or not it relates to the release of neurotransmitter.


Ischemic retinal diseases are the major cause of vision impairment worldwide. Currently, there are no available treatments for ischemia-induced retinal neurodegeneration. Circular RNAs (circRNAs) have emerged as important regulators of several biological processes and human diseases. The present study investigated the role of circRNA-ZYG11B (circ-ZYG11B; hsa_circ_0003739) in retinal neurodegeneration. Reverse transcription quantitative polymerase chain reaction (RT-qPCR) demonstrated that circZYG11B expression was markedly increased during retinal neurodegeneration in vivo and in vitro. Cell Counting Kit-8, TUNEL and caspase-3 activity assays revealed that silencing of circZYG11B was able to protect against oxidative stress- or hypoxic stress-induced retinal ganglion cell (RGC) injury. Furthermore, immunofluorescence staining and hematoxylin and eosin staining revealed that silencing of circZYG11B alleviated ischemia/reperfusion-induced retinal neurodegeneration, as indicated by reduced RGC injury and decreased retinal reactive gliosis. In addition, luciferase reporter, biotin-coupled miRNA capture and RNA immunoprecipitation assays revealed that circZYG11B could regulate RGC function through circZYG11B/microRNA-620/PTEN signaling. Clinically, RT-qPCR assays demonstrated that circZYG11B expression was markedly increased in the aqueous humor of patients with glaucoma. In conclusion, circZYG11B may be considered a promising target for the diagnosis and treatment of retinal ischemic diseases.


Objective
To investigate the effect of juanyin xiefei formula on lipopolysaccharide (LPS) induced the expression of mucin MUC5AC and explore the possible mechanism of regulation.

Methods
Human bronchial epithelial cells 16HBE were cultured in vitro.The cells were divided into 0, 0.5, 1, 6, 12 and 24h groups according to the length of LPS stimulation, and the LPS stimulation length of follow-up experiments was determined.The CCK8 method was used to detect the ability of juanyin xiefei formula about different concentration on cell proliferation of 16HBE cells and cells after stimulation with LPS, the optimum concentration of drug was selected.The experiment was divided into control group, LPS stimulation group and juanyin xiefei formula Group, using Western blot method on detection of MUC5AC and suppressor of cytokine signaling 1(SOCS1) protein expression.

Results
The high expression of MUC5AC protein induced by LPS, 0, 0.5, 1, 6, 12 and 24 h groups, the relative expression of MUC5AC gradually increased, while the relative expression of SOCS1 protein gradually decreased.The expressions of MUC5AC and SOCS1 were both medium up-regulate in 6 h group.Consequently, the application of LPS for 6 h was selected as the optimal responses period in the ensuing experiments.According to the experimental results of CCK-8 when cultured in high concentration juanyin xiefeiformulahas a growth inhibiting effect on 16HBE, when the concentration of 0.005% juanyin xiefei formula on the treatment effect of cells after LPS stimulation was the best.The concentration of follow-up drugs was 0.005%, and the action time was 48 h. After LPS treatment, the relative expression of MUC5AC in 16HBE cells was 0.251 3±0.004 3, LPS could stimulate MUC5AC expression, and the relative expression of SOCS1 was 0.427 9±0.004 0, SOCS1 expression was inhibited.After the treatment of juanyin xiefei formula and LPS, the relative expression of MUC5AC was 0.131 8±0.002 9, and decreased by 0.144 8±0.004 7.Juanyin xiefei formula inhibited the expression of MUC5AC induced by LPS (P<0.01). The relative expression of SOCS1 was 0.572 7±0.008 6, and increased by 0.119 4±0.002 3.Juanyin xiefei formula promoted the expression of SOCS1 after the action of LPS (P<0.01).

Conclusions
Juanyin xiefei formula could inhibit the expression of LPS induced airway mucin MUC5AC, the mechanism may be related with SOCS1.

Key words:
Juanyin xiefei formula; Lipopolysaccharide; Mucin 5AC; Cytokine signal transduction inhibitor 1


We describe the simulation of an inductive output tube (IOT) using the particle-in-cell code MAGIC. Simulations were performed to analyze three basic processes in an IOT: formation of bunched electrons beams from a gridded electron gun, interaction between bunched beams and rf field in a resonator, and spent beam collection with a multi-stage depressed collector. There is excellent agreement between simulation results and experimental data.


Inclusive education became the mainstream educational system in the Philippines. The study used a qualitative research design employing a case study approach. Two Mathematics teachers were observed and interviewed. Purposive sampling was used to choose the participants. Data gathering is carried out through open-ended questions, interviews, and observation. Three themes emerged in the study: lack of ASL training, personalization in pedagogy, and upskilling teachers' competency in inclusive education. This study reveals that learning should not be constrained and can be attained when everyone collaborates. It was evident that teaching is a continuous process that should not be interrupted because teaching is the noblest profession. Teachers and administrators should offer programs, projects, and activities connected to pedagogy, addressing diversity and personalizing in providing excellent services since inclusive education is now available within the educational system. It is recommended in the study to strengthen and expand inclusive education so that each student can be given more priority in accessing education for all, give them more possibilities and opportunities to address their differences, and strengthen their inherent capabilities as valuable members of society. The study seeks to contribute to the existing body of knowledge on inclusive education by exploring the experiences and perspectives of educators in the field.


Transmission electron microscopes make use of specialized cameras for the detection of electrons. This work presents the investigation of a new readout scheme for these cameras. The concept of selective readout is introduced and several selective readout schemes are proposed. Although selective readout has major benefits for the quality of the images produced by a camera, it also induces the need for a reconstruction algorithm. To this end two reconstruction algorithm types are identified that are applicable to data produced by selectively read out cameras. The first type of algorithm is an intensity reconstruction algorithm, and the second one is a classification algorithm. Both types of algorithm are developed and their performance is evaluated.


Through brushless direct current motor control system designing and the on-line simulation processing,hardware-in-the-loop simulation system based on dSPACE was presented.The experiment proved that the realtime simulation platform provided by dSPACE is possible to construct the control system model facilitatly and complete the system designing and the debugging.It demonstrates the characteristics and advantages of dSPACE system compared with other traditional tools,it can become another choice to develop system and controller.


In this document an overview of research context for the paper [PS07] is given. Beginning with an introduction to the problem domain, next a list of other modeling approaches that are applicable is given and finally the proposed approach is summarized. Multiagent System modeling is part of the large field of Artificial Intelligence, and is an approach to model " Distributed Artificial Intelligence " in literature also called " Swarm Intelligence ". In a MAS the different agents (or actors) cooperate or compete to achieve a task. Cooperation among agents in a MAS is mainly realized by means of communication. The " World " in which the agents are " living " is called MAS, it provides basic services to the agents: • message service-enables the agents to communicate with each other • definition of social dependencies-how to the agents cooperate? • security services-which agent is allowed to do what? The characteristics of MASs are that (1) each agent has incomplete information or capabilities for solving the problem and, thus, has a limited viewpoint; (2) there is no system global control; (3) data are decentralized and (4) computation is asynchronous[Syc98]. In many cases the MAS has a system-goal [Tol03]. The most powerful tools for handling complexity are modularity and abstraction. MAS offer modularity by splitting up a problem to subproblems that are solved by specialized agents 1


Heat transfer analysis of Al2O3 nanofluid in a tube with two different twist inserts is experimentally investigated. Experiments are conducted with water and nanofluid of 0.1 % particle volume with various volume flow rate for plain tube, tube with twist insert having knurling impressions and tube with twist insert having holes at equal intervals under forced convection. It is seen that the heat transfer rate increases with volume flow rate. The Reynolds Number increases with volume flow rate and is high for water + 0.1 % Al2O3 nanofluid than water. But the Nusselt Number is low for water + 0.1 % Al2O3 nanofluid than water. However from the figures it can be seen that the value of heat transfer rate of water + 0.1% Al2O3 nanofluid is high with various volume flow rates as compared to heat transfer rate value of water for plain tube, tube with twist inserts having knurling impressions and tube with twist insert having holes at equal intervals for the same correlations. Also the heat transfer coefficient of water + 0.1 % Al2O3 nanofluid is high as compared to base fluid because the addition of 0.1 % volume concentration of Al2O3 nanofluid increases the heat transfer characteristics of base fluid (water). But we found that the twist insert having holes at equal intervals has a significant effect on heat transfer than plain tube and twist insert having knurling impressions.


To match with the development of project of " Extending Agriculture Sci-Tech into Households," data reporting system of the website " China Extending Agriculture Sci-Tech into Households"was built.The system adopted the way of long distance port reporting by demonstration county,and carried out instant,centralized and standardized management.now the system have become an online management platform with date reporting,delivering and processing of " Extending Agriculture Sci-Tech into Households."


Substantial research posits that institutions do matter in port development, resulting in path-dependent reform process. However, issues remain unaddressed, notably on how and why institutions matter during such process under diversified developmental phases and geographical settings. This paper investigates, based on the experience of two major ports in East Asia, in what ways and to what extent political institutions have shaped the process of change, the main sources of path dependency, the conditions under which path disruption can occur, and how existing institutional legacies can contribute to differentiated outcomes. The focus is not only about institutional structure, but also the behavior and policies that institutions produce in such reforms. By doing so, it contributes to the progress and refinements of institutional theories, as well as theorizing the impacts of institutions in reforming the governance and planning systems of transport infrastructures.


Summary Body weights and five body nieasurements of 50 to 87 purebred Holsteins, purebred Guernseys, and reciprocal Holstein-Guernsey crosses were determined and recorded at 3, 6, 12, 18, 24, 30, 36, and 48 mo. of age. Purebreds and crossbreds were produced by alternate purebreeding and crossbreeding within a group of purebred Holstein and Guernsey foundation animals. The data were analyzed by the method of least squares to provide unbiased estimates of the effects of system of mating, breed of dam, and breed of sire. The mean of the crossbreds exceeded that of the purebreds for all six measurements, at all ages, except for height at withers at 6 mo. of age. For body weight, heart girth, and paunch girth, which are largely measures of fleshiness, the differences between crossbreds and purebreds were significant at 18 and 24 mo. of age and also at 12 mo. of age for heart girth. For depth of chest, height at withers, and length of body, which are largely measures of skeletal development, the differences were not significant at any age. The significant effects associated with system of mating in the measurements of degree of fleshiness indicate a definite heterosis at the ages of 18 and 24 mo. The data also suggest a differential action of the heterosis, such that increased heterozygosity apparently does not significantly increase the nonadditive genetic effects upon skeletal measurements, but does significantly increase rate of growth in measures of fleshiness to about 2 yr. of age. The breed of dam effect (the difference between progeny of Holstein dams and progeny of Guernsey dams) was significant at all ages for every measurement and was consistently larger than the breed of sire effect (the difference between progeny of Holstein sires and progeny of Guernsey sires). The latter effect became significant generally after about 12 mo. of age. This difference between the effects of breed of sire and breed of dam could be due to genetic differences between sires and dams of the same breed, but also suggests the possibility of an important prenatal environmental effect which persists from birth to maturity. The relative sizes of the effects of system of mating, breed of sire, and breed of dam indicate that, for all measurements, additive genetic factors are the predominant genetic influences upon rate of growth.


This paper presents a linguistic analysis of selected Turcizm which are frequent in the Macedonian language and in other Balkan languages, through the preview of phonetic adaptation to Macedonian language. Turkish had a great influence in the vocabulary of the Balkan languages, as well as the Macedonian language. Turcizm in the Macedonian language is represented by more than three thousand lexical loanwords (some of them already feel as archaisms or were not used). In that fund of words we call "Turcizm" is contained many words from Arabic and Persian origin. Turkish in these cases occurred as an intermediary in the transfer of these languages. Certain Turcizm found in our texts out from the early 16th century. They had entered the written language along with other lexical elements of our national language. The number of Turcizm in Macedonian language peaked in the 19th c., when in cities increases the frequency of Turkish language element mainly through trade and crafts. Turkish languagefor the Macedonian intelligence was language that enabled contact within the Ottoman Empire,and for the international communication. The establishment of the Macedonian literary language marked another stage in limiting the use of Turcizm. Of course, in addition to our language are used as row Turcizm completely adapted to the dictionary in the basic fund and fall into the neutral vocabulary. The purpose of the paper is to show the strong influence that has the Turkish language from centuries of synchronic plan in the Balkans, but also to give a comparative phonetic adaptation of preserved Turkish language loanwords in the Macedonian language. During the research will mostly not use methods excerption, systematization and elaboration, making the issue will approach the theoretical aspect, but also will capture the practical use of Turcizm in Macedonian language and their articulation. The spoken language will be the subject of work, precisely because of its importance to penetrating and survival of Turcizm as part of the Macedonian literary language. The largest number of Turcizm in the Macedonian language is entered through spoken language, ie direct communication between members of the population who speaking the Macedonian language and those who used in Turkish language.


The totality of human society has become existentially dependent upon the safe and secure operation of the cyber domain. It is impossible to envision a successful military operation without dependable access to the cyber domain. We will fail to comprehend the essential nature of the cyber domain if we continue to think of it as a technical or engineering system. The consequences of such a failure will be catastrophic. Machine Age thinking has become obsolete. There is now an urgent need for the development of a new, fundamentally interdisciplinary and human-centred approach to our understanding of the fifth domain. The End of the Machine Age RESILIENT CYBER ECOSYSTEMS so without a telephone or without paper records. This is apart from the use of the Internet in the operation of every aspect of the critical national infrastructure and the dependence upon the Internet of both high street banking and just in time retail logistics. Imagine a turn of events where the cash machines stopped working and bread stopped appearing on supermarket shelves for longer than 24 hours. We have known that this was coming for some time. In April 1965, barely two decades after Colossus first went into operation, Time carried a lead article that observed that to "process without computers the flood of checks that will be circulating in the U.S. by 1970, banks would have to hire all the American women between 21 and 45." The same article reflected, "Just out of its teens, the computer is beginning to affect the very fabric of society, kindling both wonder and widespread apprehension" and predicted that "swept forward by a great wave of technology ... human society is surely headed for some deep-reaching changes." [1] Our context is now that of the Information Age and although we are a product of all that has gone before, the world we inhabit has been transformed. Over time, the original foundations we used to build the intellectual and cultural constructs, which we still deploy to try to make sense of computers, have dissolved. The overhang of these now derelict constructs is starting to crumble dangerously. We need new and fresh ways of thinking about computers and about the human interactions with them. Our thinking must start from the basis of an examination of the way that computing actually operates in the twenty first century, rather than the way in which the precepts of old tell us that it should. Above all, we are in urgent need of a critical and an interdisciplinary approach to the phenomena of the cyber domain. The story of the cyber domain is principally the story of humans, not that of machines, and humanity is gloriously organic. Simultaneously, we embrace and celebrate the power and potential of the transformations of the Information Age, whilst fearing both our dependence and the actions of those who would use this vast capability against us and against our way of life. The cyber domain has the potential to be the greatest ally of democracy and its greatest enemy. Which of these it becomes is our responsibility. As the scale of our dependence becomes ever more apparent and as the awareness of the transformative potential matures, so too does the sense that our current ways of thinking and doing are irrelevant and ineffectual in the cyber domain. We have become terrified by our own creation. There is a palpable and mimetic sense of a cyber-crisis that we express through popular culture, through mainstream journalism, and through increasingly hyperbolic language. Terms such as Cyber Crime, Cyber Terrorism, Cyber War, Cyber Pearl Harbour, and Cybergeddon are commonplace. The paralysis induced by this fear is more apparent amongst the cohort of security experts than amongst the general population. The successful economies and societies of the Information Age will be built on the assumption that the world is spanned by a safe, secure, and reliable matrix of interconnected computer based information and communications systems operating at speeds and complexities beyond human perception. New economic forms and new types of entrepreneurial behaviour will emerge, not least, as mass access to cyber domain before to the prospect of orchestrated, massive, anonymised, cross border, civil disobedience. It is only a matter of, ever decreasing, time before one cause or another seeks to transpose the tactics of non-violent mass civil disobedience into the cyber domain. If, or more likely, when, this happens it will happen with lightning speed and with utter disregard to international borders. Conventional law enforcement and engineering solutions alone will be of scant use when it comes to maintaining a resilient cyber ecosystem in the face of this kind of action. The cyber domain is supra national and the tangible expressions of the power of the asymmetric cyber enabled "other" are evidential to the belief that even the might of the most powerful of nation states is confronting a challenge which it is, currently, ill-equipped to face. This is a profound disruption to a narrative forged when computers were an integral element of the Cold War arsenal and the nation state was the epitome of insuperable force. One of the tragedies of asymmetry in the Information Age is precisely that our own security related business practices and lack of agility continue to inhibit the deployment of IT capability and as such, our own best practices have a predisposition to the perverse outcome of conferring advantage on the irregular opponent. For example, Bring Your Own Device (BYOD) is an opportunity exploited by small, organic firms but, in contrast, its advantages are currently underemployed by more security-conscious, controlling companies, who risk losing competitive advantage and the real benefits of BYOD as a result. Returning to the military context, in a three-block war, the irregular opponent may well be conducting extremely granular and co-ordinated C4ISR through the medium of mobile telephones whilst regular forces are denied an equivalent tactical capability even though the technology exists to grant it. The Internet will not stop at enabling communication to facilitate the existing forms of the democratic process; it will transform the nature of democracy itself. The current forms of expression of the social contract are rooted in fundamental principles born during the European Enlightenment. Our world would be unrecognisable to Locke, Hobbes, and Rousseau. Yet, we have not yet even begun to discuss matters such as how the legitimate right to protest essential to the democratic process might translate into the cyber domain. Neither have we made sufficient progress toward establishing, let alone codifying, the normative moral and ethical precepts of good behaviour in the cyber domain. Society is now on the brink of having to contend with the formulation of legal definitions of artificial or machine consciousness and intelligence in order to allow law to operate when a computer system, or robot, is cited as the controlling mind. The relationships between the state and the citizen, and perhaps even the shape and nature of these two principal parties to the social contract are set to transform beyond recognition. The cyber domain is already at the heart of economic prosperity in the sense that without dependable, safe, and trustworthy access to it, even the most conventional of enterprises will struggle to exist, let alone compete. The prospect of running a successful business without computer-based financial accounting, without e-mail, without access to the Internet (which is commonly used for outsourcing payroll operations and the most basic banking services), and without access to the World Wide Web is now as absurd as the prospect of attempting to do CrossTalk—September/October 2012 5 As we move further towards the end of the beginning of the Information Age, it becomes ever more apparent that the narratives through which we are attempting to represent, manage, and make safe computing are being challenged. We continue to attempt to conceptualise computers and computing systems using structures and assumptions predicated on first principals formulated when computers were mainframes and the Cold War was the dominant constituent of the global economic and political context. Our grasp of a rounded and contextualised narrative of the history of computing as a societal, rather than a technical, construct is less well developed than current circumstances require. If we fail to understand our own past, we are doomed to be at the mercy of those who would claim to understand it for us. We must now transform the way we think and behave about computing. Whilst the technological dimensions of computing are, of course, central to an understanding of the phenomenon; they are subordinate in this regard to the human and social dimensions. Computing for the purpose of comprehending the cyber domain should now be framed as a sociological and anthropological system more than as a technical one. The systems and solutions architects of the future must be as much social as computer scientists. The relationships between humanity, human society, and information are profound to the point of being definitional, if not existential. Human evolutionary success is predicated on the union of our ability to use tools and our capacity to organise in increasingly sophisticated societies. Our ability to process, store, accumulate, and communicate information is at the heart of this union; it is one of the foundations upon which our tool-using ability and our social capacity themselves depend. Powerful, pervasive, and interconnected computer systems are the most sophisticated tools yet created by humankind and their essential function is to process, store, accumulate, and communicate information. Information is at the centre of our humanity. The cyber domain is the key to the future development of the human condition. Ours is the Information Age. A period in which computers


We are witnessing that the physical retail industry is changed by digital retail and the pervasiveness of smartphones, being under the pressure of integrating physical and digital, of bringing continuously in-store innovation, of investing in CX and Omni channel efforts. Retailers must give more attention to the entire shopper journey, adequately matching their customers' expectations across key areas, considering the newest solutions while looking at preferences and shopping habits, learning from Walmart's ecommerce moves, having a customer-centric approach and innovating accordingly, and the last but not the least gaining and strengthening the necessary organizational commitment.


We present a detailed spectroscopic study of the WN8(h)+B0.5 V binary system WR 147 using a non-LTE model that incorporates advances in line blanketing and allows for clumping in the wind. Ground-based optical and near-infrared observations, and high-resolution spectra obtained with the ISO Short wavelength Spectrometer are combined for this study. Previously derived interstellar extinction values of EB-V similar or equal to 4.1 mag at R-V similar or equal to 2.7 are confirmed here. The distance to WR 147 is revised slightly upwards to 650 pc, based on Galactic and LMC WN8-9 calibrators in the It band. An infrared extinction curve for this sightline reveals absorption bands at 9.7 and 18 mu m that are stronger than expected for the average ISM, but the nature and location of the intervening material is unknown.He line profiles of the WN8 star exhibit clear evidence for clumping in the wind. We find that a volume filling factor f of 0.1 yields line profile which match observations (emphasizing the electron scattering wings), though values of f in the range of 0.04 to 0.25 are reasonable. This leads to a mass-loss rate range of (1.5-3.7)x 10(-5) M., yr(-1), substantially lower than derived ft om optical or radio observations under assumptions of homogeneity. Additionally including the effects of line-blanketing, the wind performance factor, M upsilon(infinity)/(L-* /c), is reduced to similar to 2.5.Hydrogen is severely depleted, but present at 9% by mass. Observations of the [Ca IV] 3.21 mu m, [S IV] 10.51 mu m, and [Ne III] 15.56 mu m fine structure lines, from which we measure a terminal wind velocity of similar to 950 kms(-1), allow us to place constraints on the surface abundances of these elements. In all cases we find good agreement with cosmic abundances (adjusted to a hydrogen-poor environment) and thus with evolutionary predictions for WN stars.


A drug discovery and optimization platform uncovered effective therapeutic combinations for bortezomib-resistant multiple myeloma. I'll have a three-drug combo, please Combination therapy is a major strategy to circumvent the onset of treatment resistance in cancer patients; knowing which drugs to combine, however, can be difficult. Rashid et al. developed a computational platform to facilitate the discovery and optimization of drug combinations to treat multiple myeloma, a disease that often develops resistance to therapies containing the first-line drug bortezomib. The authors validated the combination treatments and refined the drug dosages in mouse models and ex vivo patient samples. Their platform requires no knowledge of which pathways to target and could more broadly aid drug repurposing efforts. Multiple myeloma is an incurable hematological malignancy that relies on drug combinations for first and secondary lines of treatment. The inclusion of proteasome inhibitors, such as bortezomib, into these combination regimens has improved median survival. Resistance to bortezomib, however, is a common occurrence that ultimately contributes to treatment failure, and there remains a need to identify improved drug combinations. We developed the quadratic phenotypic optimization platform (QPOP) to optimize treatment combinations selected from a candidate pool of 114 approved drugs. QPOP uses quadratic surfaces to model the biological effects of drug combinations to identify effective drug combinations without reference to molecular mechanisms or predetermined drug synergy data. Applying QPOP to bortezomib-resistant multiple myeloma cell lines determined the drug combinations that collectively optimized treatment efficacy. We found that these combinations acted by reversing the DNA methylation and tumor suppressor silencing that often occur after acquired bortezomib resistance in multiple myeloma. Successive application of QPOP on a xenograft mouse model further optimized the dosages of each drug within a given combination while minimizing overall toxicity in vivo, and application of QPOP to ex vivo multiple myeloma patient samples optimized drug combinations in patient-specific contexts.


The human voice is indicative of a variety of characteristics. It may be particularly influential in judgments such as of charisma. But what features of the voice are indicators of these characteristics? Osgood et al. (1957) suggested that a vast array of stimuli are judged by humans along the three dimensions of evaluation, potency, and activity. We tried to determine whether voices are also judged according to these three dimensions. Male and female judges rated 36 short (2 s) segments of voice segments from a variety of languages on Osgood et al.'s dimensions, using 9 different scales. Listeners were able to make their judgments quickly, even though the stimuli were short. Confirmatory factor analysis failed to produce the three factor structure from the listener's judgments of the voices. Gender and language of the voices did not help clarify the structure of the judgments. Hence, this study demonstrates that human voices are unique stimuli that may be judged using a more complex framework.


Introduction Buprenorphine/Naloxone (BP/NLX) is an effective drug combination used in long-term maintenance therapy in opiate use disorder (OUD). In some studies, abstinence over 180 days was defined as long-term remission (1). Objectives The aim of this study is to determine the sociodemographic and clinical characteristics of patients in long-term remission with BP/NLX. Methods In this study, 30 patients who were followed up with OUD at Akdeniz University Addiction Center and were in remission with BP/NLX for at least 180 days were evaluated retrospectively. Results Sociodemographic and clinical characteristics are summarized in table 1. Conclusions OUD is associated with lower quality of life and employment rate (2). In our study, the rate of working in a regular job is high. It can be concluded that prolonged remission improves functionality in patients. Although patients are in remission for a long time in terms of opiate use, 20% of patients continue to use cannabis and 10% continue to use cocaine. In a study, there was no difference in productivity and quality of life between BP users with and without current cannabis use. Continued use of cannabis by patients may be related to this condition. However, cannabis use increases many mental illnesses, especially psychosis (4). In patients in remission with BP/NLX, studies should also be carried out to avoid other substances than opiates. In our study, in accordance with the literature (5), no negative effects on kidney and liver functions were observed with long-term BP/NLX treatment. BP/NLX appears to be safe in prolonged use. Disclosure No significant relationships.


Preface to the Second Edition Preface Note on Transliteration and Dating Part One The Rise and Fall of the Georgian Monarchies 1 The Formation of the Georgian Nation 2 Christian Georgia: The First Thousand Years 3 The Long Twilight of the Georgian Kingdoms Part Two Georgia in the Russian Empire 4 Russian Rule and Georgian Society 5 Emancipation anh the End of Seigneurial Georgia 6 Thge Emergence of Political Society 7 Marxism and the National Struggle 8 The End of Tsarist Georgia Part Three Revolutionary and Soviet Georgia 9 Revolution and Republic 10 Bolshevik Georgia 11 StalinOs Revolution 12 Stalinism in Georgia 13 Georgia and Soviet Nationality Policy since Stalin 14 The Georgian Road to Independece Glossary Notes Bibliographical Note Index


American credit system has gone through the three phases: free credit system,restrictive credit system,and elastic credit system,which combined German educational experience and its pragmatic educational ideas and adapt to demand of development of American higher education.In China,there are some misconceptions in the process of implementing the credit system because of the influence of such factors as trend of industrialization of education,lacking corresponding educational philosophy and lagging behind of institutional improvement.Therefore,we must examine and push forward the teaching reform of credit system in the context of internationalization from the perspective of globalization,clearing up the misconceptions of understanding.We make efforts to explore the credit system consistent with Chinese conditions and the universities' situation,based on the concept of the complete credit system.Under the conduct of "Overall Pluralism",we push forward the reform of credit system and continuously perfect the rules for implementation of credit system.


St. Charles, Ill. — Dermatologist Rany Jazayerli, M.D., says he knew he'd hit the big time when he stumbled upon his own profile on the online encyclopedia Wikipedia.


Michael Jackson is remembered for his gift of music as well as his tragic life. His celebrity seemed to have isolated him from normalcy, and one hopes that his tragic life does not affect his three children.


Reproducing kernel Hilbert spaces are elucidated without assuming prior familiarity with Hilbert spaces. Compared with extant pedagogic material, greater care is placed on motivating the definition of reproducing kernel Hilbert spaces and explaining when and why these spaces are efficacious. The novel viewpoint is that reproducing kernel Hilbert space theory studies extrinsic geometry, associating with each geometric configuration a canonical overdetermined coordinate system. This coordinate system varies continuously with changing geometric configurations, making it well-suited for studying problems whose solutions also vary continuously with changing geometry. This primer can also serve as an introduction to infinite-dimensional linear algebra because reproducing kernel Hilbert spaces have more properties in common with Euclidean spaces than do more general Hilbert spaces.


In the production of liquid thiocol, two stages are distinguished: the synthesis of di--chloroethyl formaland the production of the final product based on it. In the course of the technological process, the air environment of the working premises is polluted with harmful chemicals.


The piecewise flat space–time is equipped with a set of edge lengths and vertex coordinates. This defines a piecewise affine coordinate system and a piecewise affine metric in it, the discrete analogue of the unique torsion-free metric-compatible affine connection or of the Levi-Civita connection (or of the standard expression of the Christoffel symbols in terms of metric) mentioned in the literature, and, substituting this into the affine connection form of the Regge action of our previous work, we get a second-order form of the action. This can be expanded over metric variations from simplex to simplex. For a particular periodic simplicial structure and coordinates of the vertices, the leading order over metric variations is found to coincide with a certain finite difference form of the Hilbert–Einstein action.


In order to examine the effectiveness of moxibustion stimulation for climacteric disturbance, we administered moxibustion stimulation to ovariectomized (OVX) rats, and compared the tail surface temperature, laboratory parameters, and the level of locomotor activity with those of untreated rats. Twenty-four female Wistar rats (8 weeks old, 160 - 180 g) were divided into three groups. The rats in the OVX-M group underwent moxibustion stimulation after ovariectomy. The rats in the OVX-C group underwent ovariectomy but did not receive moxibustion stimulation. The rats in the Normal group received neither ovariectomy nor moxibustion stimulation. The level of locomotor activity was determined by a metabolism measuring system. The tail surface temperature was significantly lower in the OVX rats before moxibustion stimulation than in the Normal group. In the OVX rats before moxibustion stimulation, there was no clear difference in the level of locomotor activity between the active and resting phases, and the pattern of locomotor activity was irregular. After moxibustion stimulation, the tail surface temperature of the OVX-M group did not significantly differ from that of the Normal group, and the pattern of locomotor activity of the OVX-M group became diphasic with clear active and resting phases, similar to that observed in the Normal group. These results demonstrate that moxibustion stimulation is effective for the treatment of climacteric disturbance.


Objective Study of the multifocal electroretinogram and the ultrastructure changes after retinal detachment in rabbits. Methods Construction model of rhegmatogenous retinal detachment(RRD) in 18 eyes from 9 rabbits,detect multifocal electroretinogram(mfERG) before and after construction model,observe the ultrastructure changes by transmission electron microscope (TEM). Results 10 days after RRD P1-wave amplitude density decreased(P=0.013),P1-wave amplitude value decreased(P=0.01),and N1-wave amplitude value decreased(P=0.053).By light microscope granular layer of neural got thin,the vacuole in nerve fiber layer and inner granular layer.The cilia of retinal pigment epithelium disappeared completely by TEM,the granula of retinal pigment epithelium decreased,the rough endoplasmic reticulum,the mitochondrial crista breaks,the outer nuclear layer arrangemen disorderin,disc broad,the vacuole inner and outer plexiform layer shaped,the ganglion cells and membranous of eye cell outer side got think,intermembranous space gotorgancelle disappeared mostly,the crista of cytoplasm ganglion cells layer swelled. Conclusions The retina will get pathological changes 10 days after RRD,P1-wave amplitude density decreases,P1-wave amplitude value decreases,and N1-wave amplitude value decreases in mfERG.


In order to enhance the performance of interference location for satellite systems based on TDOA Measuremen, a new TDOA parameter estimation method based on Secondary correlation TDOA estimation, combined with improved threshold wavelet de-noising, is presented. By the use of the characteristic of the wavelet de-noising, The algorithm overcomes the limitations of the Hilbert second correlation method which requires a priori knowledge of the signal and noise, able to accurately estimate the TDOA parameters of the signal in the low SNR environment and effectively improve the performance of satellite interference location. The simulation results illustrate the reliability and effectiveness of this new TDOA estimation method for satellite interference localization.


In their very interesting case report, Blaquiere and his colleagues (1982) comment on the postulated higher incidence of peripheral neuropathy in myeloma with sclerotic lesions. They cite a previous study of ours (Evison & Evans, 1967) as disputing this association.


Let [FORMULA] be a complex polarized manifold of dimension [FORMULA]. In this paper, we give a classification of [FORMULA] with [FORMULA] and [FORMULA]. In order to classify these [FORMULA], we study a classification of [FORMULA] which satisfies [FORMULA] and [FORMULA]. Moreover we also classify [FORMULA] with [FORMULA], [FORMULA] and [FORMULA].


Three different types of modified BNNSs were designed to experimentally demonstrate the importance of integrated basal crystal lattices for polymer/BNNSs film capacitors.


An infinite plate weakened by doubly distributing cracks is studied in this paper. Two loading cases, the remote tension and the remote shear stresses, are assumed. Analysis is performed for a cracked cell cut from the infinite plate. It is found that the eigenfunction expansion variational method is efficient to solve the problem. The stress intensity factor, the T-stress, and the elastic response are evaluated. The cracked plate can be equivalent to an orthotropic medium without cracks. The equivalent elastic constants are presented. ©2002 ASME


Modeling competences is a real challenge for the people working in a lot of domains like human resource (HR), companies, e-Learning related activities, universities and not only. Universities and e-Learning organizations define the prerequisites that must be satisfied before joining the university and define also the competences that will be acquired after successful completion. After, the curricula or training programs are stated. The future students and companies mainly HR departments try to define their own competences and these are compared with those offered by the applicants and universities respectively. The proposed model will be included in the project Cex 05-D8-66/2005. Based on a multi-agent system, it will offers to the universities, companies and students the capabilities for defining and presenting the competencies, making comparisons between them with appropriate scores and evaluations in order to use them in an efficient way.


This paper discusses generalized controllers for rigid formation shape stabilization. We provide unified analysis to show convergence using different controllers reported in the literature, and further prove an exponential stability of the formation system when using the general form of shape controllers. We also show that different agents can use different controllers for controlling different distances to achieve a desired rigid formation, which enables the implementation of heterogeneous agents in practice for formation shape control. We further propose an event-triggered rigid formation control scheme based on the generalized controllers. The triggering condition, event function and convergence analysis are discussed.


Despite the challenged contention that consumers serve more onto larger dinnerware, it remains unclear what would cause this and who might be most at risk. The results of five studies suggest that the neglected Delboeuf illusion may explain how the size of dinnerware creates two opposing biases that lead people to overserve on larger plates and bowls and underserve on smaller ones. A countercyclical sinus-shaped relationship is shown to exist between these serving biases and the relative gap between the edge of the food and the edge of the dinnerware. Although these serving biases are difficult to eliminate with attention and education, changing the color of one's dinnerware or tablecloth may help attenuate them. By showing that the Delboeuf illusion offers a mechanistic explanation for how dinnerware size can bias serving and intake, we open new theoretical opportunities for linking illusions to eating behavior and suggest how simple changes in design can improve consumer welfare.


A fundamental tenet of the New Federalism is that many social welfare problems are a result of federal usurpation of responsibilities belonging to those institutions nearest the people. According to the New Federalism, state and local governments and public/private partnerships involving private, nonprofit organizations are the most appropriate mechanisms for dealing with social welfare responsibilities. To remedy the problem offederal usurpation, the Reagan administration proposed severe cuts in federal spending for social welfare programs. New data suggest that, while significant, actual cuts were not as great as originally feared by some. Yet these cuts appeared to work counter to their stated objectives. The cuts weakened the extensive public/private partnerships already existing in many communities, and forced nonprofits to adopt more entrepreneurial strategies to make up for lost government funds. These changes have raised major questions about the future role of public/private partnerships and the nonprofit sector in addressing the needs of communities.


A decade ago in a paper, "Reassessing Discretionary Fiscal Policy," published in the Journal of Economic Perspectives, I concluded that "in the current context of the US economy, it seems best to let fiscal policy have its main countercyclical impact through the automatic stabilizers. ... It would be appropriate in the current circumstances for discretionary fiscal policy to be saved explicitly for longer term issues, requiring less frequent changes." This was not an unusual conclusion at the time. As Martin Eichenbaum (1997) put it, "There is now widespread agreement that countercyclical discretionary fiscal policy is neither desirable nor politically feasible," or, according to Martin Feldstein (2002), "There is now widespread agreement in the economics profession that deliberate 'countercyclical' discretionary policy has not contributed to economic stability and may have actually been destabilizing in the past." Despite this widespread agreement of a decade ago, there has recently been a dramatic revival of interest in discretionary fiscal policy. The purpose of this short paper is to review the empirical evidence during the past decade and determine whether it calls for such a revival. I find that it does not.


Classifying common atoms in organic compounds in terms of families in periodic table of elements and hybridization states, a novel rotation–translation invariant Three-Dimensional Molecular Structural Characteristic (3D-MSC) method, Three-Dimensional Holographic Vector of Atom Interacting Field (3D-HoVAIF), is proposed by calculating three kinds of interatomic nonbonding interactions namely electrostatic, van der Waals, and hydrophobic interactions. In an attempt to apply 3D-HoVAIF into QSAR studies on antimalarial activities of 32 artemisinin derivatives, the resulting Genetic Algorithm-Partial Least Square (GA-PLS) model is confirmed to be stable and predictable by both modeling validation and methodological contrast. For external test set, the 3D-HoVAIF model has correlation coefficient (qext2) and Root Mean Square Error of Prediction (RMSEP) of 0.751 and 0.372, respectively.


This paper presents a field-programmable gate array (FPGA)-based digital down
 converter (DDC) that can reduce the bandwidth from about 70 MHz to 182.292
 kHz. The proposed DDC consists of a polyphase COordinate Rotation DIgital
 Computer (CORDIC) processor and a multirate filter. The advantage of
 polyphase CORDIC processor is to process with high sample rate input data
 and produces computational efficient noiseless baseband spectrum. The
 pipeline multirate filter works at a high clock speed. Moreover, the
 multirate filter generates a fractional sample rate factor using a cubic
 B-spline Farrow filter. The proposed DDC is coded with optimal hardware
 description language (HDL) and tested on Kintex-7 Xilinx FPGA as the target
 device. Experimental results indicate that the proposed design saves chip
 area, power consumption and operates at high speed without loss of any
 functionality. Additionally, the proposed design offers sufficient
 spurious-free dynamic range (SFDR) and produces less than 1 Hz frequency
 resolution at the output.


Taxes on unhealthy foods and sweetened beverages, as well as subsidies to healthy foods, have become increasingly popular strategies to curb obesity. The existing evidence on the welfare effects of fiscal policies is mixed and almost uniquely focused on tax schemes. Using the 2016-2017 Household Budget Survey in Chile, we estimate an Exact Affine Stone Index (EASI) incomplete demand system and simulated changes in purchases, tax incidence and consumer welfare of three different policy scenarios: (1) an 18% tax on unhealthy food and sweetened beverages, (2) a subsidy defined as zero-rating fruits and vegetables from the current 19% value-added tax, and (3) a combined (tax and subsidy) policy. The combined scheme captures the incentives to switch purchases from both single-policy alternatives, creating almost no change in government revenue. In terms of welfare, low income households strictly benefit from a combined policy, while high income households experience a loss of consumer welfare, thus generating significant re-distributional effects.


PURPOSE: A Top-down construction method through front end extension is provided to maximize bearing force of the tip of a column by constructing the front end of a column so that a stud meets the extension portion of the front end. CONSTITUTION: A Top-down construction method through front end extension comprises the steps for: constructing a retaining wall; vertically excavating from the position of a column(200) over the ground to the position of concrete bulb of the lowermost layer mat foundation; expanding the excavation caliber by executing horizontal excavation or executing horizontal excavation and perpendicular excavation by turns to the concrete bulb position of the lowermost layer mat foundation; constructing a column in the excavated column position forming the front end of the column as concrete bulb(200c) by filling expanded excavation portion under the mat foundation with concrete; constructing an interlayer structure; blasting; repeatedly executing the above process to the lowermost layer; executing the last blasting to the mat foundation position; and constructing the mat foundation.


Abstract The minimum variance (MV) lower bound has been applied to many multivariable control systems in order to assess their performance based on routine operating data. However, such analysis often depends on the selection of a suitable dynamic model of the data and for multivariable systems, there can be many candidate models. Also, uncertainty is often not considered, because standard approximations do not exist for the sampling distribution of these multivariable performance indices. This paper addresses these two issues by using the Bayesian approach to vector autoregression (VAR) modelling with Markov Chain Monte Carlo (MCMC) numerical methods. Dynamic model selection is carried out by using Reversible Jump (RJ) MCMC and it is shown that MCMC can be used to the estimate the non-standard distributions that exist in multivariable MV performance indices. The approach is applied to data from an industrial cross-directional (CD) control system by using a more general class of model than has previously been studied for these systems.


Increasing research indicates the effectiveness of simulation-based learning as a means of socio-emotional learning (SEL). Traditionally, simulations are conducted face-to-face (FTF) with a live actor in the role of the 'other'. The outbreak of COVID-19 led to the shifting of simulations to online settings. To explore the differences between FTF and online conditions, questionnaires were administered to 49 FTF participants, 87 online participants, and 50 control participants;11 participants who experienced both experimental conditions were interviewed. Results revealed that online simulations contributed to similar SEL growth as FTF. Interviews highlighted differences in the subjective experience of FTF and online participants. [ FROM AUTHOR] Copyright of European Journal of Teacher Education is the property of Routledge and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)


This paper achieved simulation system for dynamic process of land ecological system with Visual C++ and Microsoft ActiveX controls,integrated dynamic linking library(DLL) by Fortran program,including chart analyzers and exported data produces of Microsoft Excel chart.This system had been verified and applied initially on the North China Plain.


Introduction: The abutment screw loosening has been a common clinical mishap affecting the success of the implant in the long run. With repeated insertion and removal of the implant abutment screw during fabrication of the restoration, frictional wear at the microscopic level in the screw threads had been reported. Aim: To assess the effectiveness of screw coating in minimizing abutment screw loosening in dental implants in literature. Results: A database search yielded a total of 14 articles out of which 8 were excluded based on the title and abstracts not relevant to the topic of our interest and 6 were included based on the core data. The six articles were reviewed, and four articles were consolidated to perform the meta-analysis. All the four studies showed a similar expression of outcome measure; the detorque values were expressed in Ncm. The χ2 = 144.71, df = 3, p < 0.00001, and I2 = 98%. Hence, a Random Effect model with 95% confidence interval was chosen for meta-analysis. The overall effect observed in the metaanalysis was Z = 0.36, p = 0.72, and no statistically significant differences were observed between the coated and noncoated screws with respect to detorque values. Conclusion: This meta-analysis inferred that there is no difference between the coated and noncoated screws with respect to screw loosening. Clinical significance: Noncoated screws are equally effective as coated screws with respect to abutment loosening in endosseous implants. Hence, the additional cost and technique sensitivity incurred with powdered screws may not drastically improve the rate of failure due to screw loosening.


This article presents the outcomes of a research that aimed at analyzing the impact of educational policies for Information and Communication Technologies (ICT) such as the National Program of Informatics in Schools (Programa Nacional de Informatica na Escola – ProInfo) in the routine of Elementary Schools in two towns of the Porto Alegre Metropolitan region, RS. The theoretical support is based on Peter McLaren, Stephen J. Ball and Berger and Luckmann. The data was collected from teachers working for more than 20 years and included documental analysis, interviews, narratives and group discussions. The study demonstrated that a) positive effects in the quality of education through the use of Information and Communication Technologies which is the result of individual


The aim of present research was to assess physicochemical and grain qualities of traditional land races and rice cultivars native to temperate region (Tamil Nadu) of India. Traditional varieties in India and across the Asia serious threat of extension because of arrival of high yielding varieties, hybrids, genetically engineered rice came for nowadays to increase the malnutrition and different human disease is the major problem. Trial material comprised of ten parents which comprised in six cultivars of female parents and four conventional landraces utilized as male parents, F 1 , F 2 and F 3 generation of six crosses. Parents and two crosses viz., IR 72 x Veeradangan, ADT 39 x Kavuni were chosen F 3 generation dependent on the biometrical characters present in quality and nutritional traits in grains. These desirable characteristics (nutritional, grain quality) exploit farmers to preserve these traditional and improved cultivars encourage farmers to cultivate.


the prevention of peroperative hypothermia. Acta Anaesthesiol Scand 1998: 42: 348-352. 2. English M, Farmer C, Scott A. Heat loss in exposed volunteers. J Trauma 1990: 30: 422425. 3. Kristensen G, Guldager H, Gravensen H. Prevention of peroperative hypothermia in abdominal surgery. Acta Anaesthesiol Scand 1986: 30: 314-316. 4. Bickler PE, Sessler DI. Efficiency of airway heat and moisture exchangers in anesthetized humans. Anesth Analg 1990: 71: 415418.


Background: The COVID-19 pandemic has posed unprecedented stress globally. Though less susceptible to severe forms of COVID-19 infection, young people too have suffered psychological impacts. As negative emotions and worries in adolescence can persist, incurring significant healthcare burden, measuring these during the pandemic can signpost later mental health needs particularly in low-resource settings. Here we report on experiences of coronavirus and its' impact on negative emotions and worries in Indian adolescents. Methods: Three-hundred-and-ten young people from North India (51% male, 12-18 years) were recruited to a longitudinal online survey. At baseline, participants reported on their demographics, personal experiences and knowledge of others infected by the coronavirus, extent of social restrictions, the impact of the coronavirus on various life domains, their top three worries, and levels of negative affect and absence of positive affect (anhedonia). Findings: Most participants had no personal experience (97.41%) or knew anyone (82.58%) with COVID-19 yet endorsed moderate-to-severe impact of COVID-19 on their academic studies, social life, and work. Participants top three worries focused on academic attainments (7.82%), social and recreational activities (6.99%), and physical health (3.98%). More females than males worried about academic attainment and physical health while more males were worried about social and recreational activities. The impact of COVID-19 on social life, family relationship, physical health, emotions, and caring responsibilities associated with negative affect. Lower family income correlated with higher anhedonia as did the impact of COVID on physical health. Interpretation: Indian adolescents report significant impact of the pandemic on various aspects of their life and are particularly worried about academic attainments, social and recreational activities and physical health. These findings call for a need to ensure provisions and access to digital education and medical care. Funding: LR is funded by an ESRC grant to JYFL. TH is funded by Mental Health Research UK.Declaration of Interests: The authors declare no competing interests.Ethics Approval Statement: This study received approval from the Institutional Ethics Committee, Institute of Medical Sciences, Banaras Hindu University (Ref No.: Dean/2020/EC/1975) and King's College London Research Ethics Committee (Ref: HR-19/20-18250).


Carbon fiber and silica filled epoxy is studied as underfill in flip chip.Because of the negative thermal expansion coefficient of carbon fiber,this underfill has much lower thermal expansion coefficient than that of silica filled epoxy or epoxy underfill. Simulation and experiment results prove that it can greatly increase the faigue life of flip chip solder joints than that of silica filled epoxy or only epoxy itself as underfill.Compared with Engelmaier's solder joints prediction fatigue life model,Coffin-Manson's model is highly evaluated than that of[E-W]model and practical experimental fatigue life.


We consider an electron system under conditions of strong Anderson localization, taking into account interelectron long-range Coulomb repulsion. We establish that at sufficiently low electron densities and sufficiently low temperatures the Coulomb electron interaction brings about ordering of the Anderson-localized electrons into a structure that is close to an ideal (Wigner) crystal lattice, provided the dimension of the system is >1. This Anderson–Wigner glass (AWG) is a new macroscopic electron state that, on the one hand, is beyond the conventional Fermi glass concept, and on the other hand, qualitatively differs from the known "plain" Wigner glass (inherent in self-localized electron systems) in that the random slight electron displacements from the ideal crystal sites depend essentially on the electron density. With increasing electron density the AWG is found to turn into the plain Wigner glass or Fermi glass, depending on the width of the random spread of the electron levels. It is shown that the ...


Observing the current legal system and theory of America, "piercing the corporate veil" is in a state of "chaos" in both of them. How can China learn from the rule of law and the theory of "piercing the corporate veil"? How to avoid its harm and gain its benefits? Due to different national conditions and judicial systems, also differences between civil law system and common law system, and at the same time, the world is in the era of globalization, the exchange of legal culture of Chinese legal system is expanding and deepening day by day. Therefore, it is necessary to study the rule and theory of "piercing the corporate veil". This paper systematically summarizes the current situation of the rule and theory of "piercing the corporate veil" in America, explores the causes of the confusion, and puts forward some suggestions to prevent the occurrence of problems in China after transplanting this rule, which is very necessary and timely.


The article reports regulatory developments in the financial services market in Indonesia as of September 2016. Also cited are the signing by Indonesian President Joko Widowo of a presidential directive that abolishes the minimum capital requirement for establishing a business, the freedom of contract principle, and the capitalisation requirement by the Capital Investment Coordination Board of Indonesia (Badan Koordinasi Penanaman Modal (BKPM).


Objective:To evaluate the microtensile bond strength of total-etch or self-etch adhesives to caries-affected dentine versus normal dentine. Methods:Twenty-four extracted human molars with mesial coronal carious lesions extending into mid-dentin were selected. The softened carious dentine was removed with a slow-speed, carbon-steel bur and Caries Marker was used as guides. Prepared cavity in sound dentine in the distal coronal part of the identical teeth was used as the control. Surfaces were bonded with either PrimeBond NT, Adper Single Bond 2, Adper Prompt or XenoⅢ,according to manufactures' recommendations. A crown was built up using resin composite(Filtek P60).After storage in water (37 ℃,24 h),teeth were vertically serially sectioned into 1.0 mm thick slabs and trimmed to yield 1 mm2 test area that contained either caries-affected or normal dentine. Then the specimen were tested in tension in an Instron machine at 0.8 mm/min.The bonding interface between the dentine and adhesives was qualitatively evaluated under the observation of scanning electron microscope(SEM). Results:Two total-etch adhesives yielded higher bond strengths than the two self-etching systems. And all the adhesives attained higher strengths in normal than in caries-affected dentine(P0.05). SEM analysis showed that the hybrid layer in caries-affected dentine was thicker but more porous than that in normal dentine. Compared with normal dentine, there was fewer resin tag exhibited in caries-affected dentine. Conclusion:The two total-etch adhesives evaluated produce higher bond strengths to normal and caries-affected dentine than the two self-etching systems.


BACKGROUND
Real-time three-dimensional echocardiography (RT-3D-Echo) and ultrafast computed tomography (CT) are two novel methods for the analysis of LV ejection fraction and volumes.

OBJECTIVE
To compare LVEF and volume measurements as obtained using RT-3D-Echo and ultrafast CT.

METHODS
Thirty nine consecutive patients (27 men, mean age of 57+/-12 years) were studied using RT-3D-Echo and 64-slice ultrafast CT. LVEF and LV volumes were analyzed.

STATISTICAL ANALYSIS
coefficient of correlation (r: Pearson), Bland-Altman analysis, linear regression analysis, 95% CI, p<0.05.

RESULTS
RT-3D-Echo measurements: LVEF ranged from 56.1 to 78.6 (65.5+/-5.58)%; end-diastolic volume ranged from 49.6 to 178.2 (87+/-27.8) ml; end-systolic volume ranged from 11.4 to 78 (33.1+/-13.6) ml. CT scan measurements: LVEF ranged from 53 to 86% (67.8+/-7.78); end-diastolic volume ranged from 51 to 186 (106.5+/-30.3) ml; end-systolic volume ranged from 7 to 72 (35.5+/-13.4)ml. Correlations between RT-3D-Echo and CT were: LVEF (r: 0.7888, p<0.0001, 95% CI 0.6301 to 0.8843); end-diastolic volume (r: 0.7695, p<0.0001, 95% CI 0.5995 to 0.8730); end-systolic volume (r: 0.8119, p<0.0001, 95% CI 0.6673 to 0.8975).

CONCLUSION
Good correlation between LVEF and ventricular volume parameters as measured by RT-3D-Echo and 64-slice ultrafast CT was found in the present case series.


Abstract Background There is a high prevalence of COVID-19 in university-age students, who are returning to campuses. There is little evidence regarding the feasibility of universal, asymptomatic testing to help control outbreaks in this population. This study aimed to pilot mass COVID-19 testing on a university research park, to assess the feasibility and acceptability of scaling up testing to all staff and students. Methods This was a cross-sectional feasibility study on a university research park in the East of England. All staff and students (5625) were eligible to participate. All participants were offered four PCR swabs, which they self-administered over two weeks. Outcome measures included uptake, drop-out rate, positivity rates, participant acceptability measures, laboratory processing measures, data collection and management measures. Results 798 (76%) of 1053 who registered provided at least one swab; 687 (86%) provided all four; 792 (99%) of 798 who submitted at least one swab had all negative results and 6 participants had one inconclusive result. There were no positive results. 458 (57%) of 798 participants responded to a post-testing survey, demonstrating a mean acceptability score of 4.51/5, with five being the most positive. Conclusions Repeated self-testing for COVID-19 using PCR is feasible and acceptable to a university population.


The editorial office of the Journal of Zoo and Wildlife Medicine recognizes the following individuals for their dedication and service to the Journal for serving as a peer reviewer for manuscripts processed in 2016. The number in parentheses indicates the number of manuscripts reviewed.


Abstract: To evaluate the possible role of high risk Human Papilloma viruses (HPV) 16 and 18 in oral squamous cell carcinomas (OSCC), 40 SCCs and 15 benign lesions were analyzed for the presence of HPV DNA. The investigation followed a case-control design. Cases consisted of patients diagnosed with OSCCs. Controls were patients diagnosed with benign oral lesions. Information concerning all study subjects were retrieved from hospital records. Genomic DNA was isolated from the formalin-fixed paraffin embedded tissue (FFPET) specimens and tested for detection of HPV DNA by polymerase chain reaction (PCR). Pearson Chi-square test for statistical significance (P value), with the 95% confidence level and confidence intervals were used. HPVDNA was detected in 15% of cases (six out of 40 cases), and none of controls (n=15), P <0.0001. Among the six positive cases four were HPV type 18 and the remaining two were type 16. These results provide evidence supporting causal association between HPV infection and oral SCC in Sudan.


The relationship between incarceration rates and crime rates and the need for a rethinking of the place of imprisonment in current criminal justice policy in the U.S. is discussed. The limited benefit of prison in controlling crime is highlighted.


An experimental package was constructed to operate a loop heat pipe (LHP) in microgravity aboard NASA's KC-135 aircraft. Startup of the LHP was performed in flight and ground testing. Data revealed different temperature profiles for similar startups indicating different locations of the vapor and liquid inventories. A sharp increase in evaporator temperature of approximately 10 K followed by a small decrease was very comparable to startups in capillary pumped loops. In contrast, a steady linear rise in wall temperatures with time was used to indicate the absence of liquid in the vapor sections of the evaporator. Temperature transients in the liquid line during particular startups indicate movement of fluid out of the compensation chamber and into the liquid line. Experimental results match expected behavior and show a high degree of repeatability.


An unusual application of Piaget's stage-theory of cognitive development is presented. It is hypothesized that, when the child reaches the concrete operational stage of development, he or she also ceases to believe in Santa Claus. An analysis of the reasoning that led to the formation of this hypothesis as well as an enumeration of its implications for both psychologists and laymen are also presented.


Abstract Important scholarship in International Relations (IR) theory engages with the utopian tradition in order to render it 'realistic', whereby 'failed' utopian projects become necessarily unrealistic, and anti-political. The paper suggests such scholarship is informed by a narrow chronotic register, and a dichotomous ontology of chronos and kairos derived in part from the work of Karl Mannheim and E.H. Carr. As such, utopian scholarship in IR constructs a self-reinforcing relationship between change and realism, whereby only 'realistic' interventions can affect normatively desirable change, and therefore only interventions that are possible under current social and political conditions are normatively desirable. Drawing on the idea that the quest for utopia must always fail, the paper suggests that IR theory should be far more attuned to 'failure' than as simply a phenomenon that helps define the boundary between the realistic and unrealistic. The paper draws on non-canonical literatures from utopian studies and anarchism, to furnish an alternative 'no-point' form of utopianism that dissolves the chronos/kairos binary and thus engages neither in universalist and violent end-point, nor institutionally compromised 'mid-range' utopianism. This acts to reconceptualise 'failure' in excess of itself, a productive site for IR scholarship, and a political archive for movements and struggles to learn from.


This paper deals with the numerical solutions and convergence analysis for general singular Lane–Emden type models of fractional order, with appropriate constraint initial conditions. A modified reproducing kernel discretization technique is used for dealing with the fractional Atangana–Baleanu–Caputo operator. In this tendency, novel operational algorithms are built and discussed for covering such singular models in spite of the operator optimality used. Several numerical applications using the well-known fractional Lane–Emden type models are examined, to expound the feasibility and suitability of the approach. From a numerical viewpoint, the obtained results indicate that the method is intelligent and has several features stability for dealing with many fractional models emerging in physics and mathematics, using the new presented derivative.


From uvby photometry of 75 stars in the direction of NGC 7063 we were able to determine membership of some stars and fix the distance (722± 105 pc), log age (8.146) and reddening (E(b − y) = 0.091 ± 0.039 mag) for the cluster.


Parasitic weeds belonging to the Orobanchaceae family are a menace in Sub-Saharan African (SSA). Specifically, the two witchweeds from the genus Striga, S. hermonthica and S. asiatica, are jointly responsible for land abandonments and cereal yield reductions in the SSA. Factorial experiments involving fourteen maize genotypes and two levels of Striga asiatica infestation (infested and noninfested) were conducted under pot and laboratory experiments at the Department of Plant Production Sciences and Technologies, University of Zimbabwe, during the 2014/2015 season. A 14 × 2 factorial pot experiment was arranged in a 7 × 4 α-lattice design replicated four times, whereas the laboratory agar gel was arranged in a complete randomized design with four replications. Results revealed significant differences (

 p

  < 0.05) for S. asiatica and genotype main effects for the recorded traits. S. asiatica-infested genotypes had lower biomasses than noninfested ones. However, the University of Zimbabwe bred hybrids such as Ax31, Ax28, Ax7, and Ax32 had similar plant heights and stem, leaf, and cob biomass across the two Striga levels unlike the local checks, particularly SC513, SC537, and SC637, under Striga infestation. Moreover, these genotypes also had the least Striga germination percentage and furthest germination distance indicating that they are resistant/tolerant to Striga asiatica. The University of Zimbabwe bred hybrids, using Striga hermonthica resistance from the International Institute of Tropical Agriculture, exhibited resistance/tolerance to Striga asiatica compared to local checks. Therefore, these varieties could offer a better and viable Striga spp. control option to farmers in both S. hermonthica and S. asiatica endemic areas.


In this study, it was evaluated about shrinkage properties of high strength concrete according to poly mix fiber and moisture evaporation condition. As a results, When concrete was mixed with poly mix fiber of spalling control, it reduced effect of shrinkage independent of the evaporation conditions of unsealed and sealed.


A composition for controlling a plant disease containing a carboxamide compound represented by the formula (I): Formula ** **, wherein R1 represents hydrogen or methyl and R2 represents methyl, difluoromethyl or trifluoromethyl, characterized in that the ratio enantiomeric form R / S form the carboxamide compound 90/10 to 10,000 / 1.


It is argued that in this era of globalisation and knowledge economy competitive advantage is a result of firm-specific resources and capabilities with characteristics of value, rareness, inimitability and non-substitutability. Accordingly, firms consider organisational learning, knowledge management and innovation as intangible resources for achieving competitive advantage however; little research has empirically examined the relationships between these resources especially in developing countries. The purpose of this paper is to empirically explore in a single model the relationships between organisational learning and competitive advantage with the interacting influence of knowledge management and innovation in a developing country such as Uganda in the Sub-Saharan Africa. The findings indicate that there is a positive relationship between organisational learning and competitive advantage and that the interactive influence of knowledge management and innovation increases the predictive power of the relationship. This paper discusses these findings and provides theoretical and managerial implications.


Optic nerve injury is one of the most common and serious complications in traumatic brain injury (TBI). Alleviating degree of optic nerve injury is important to cure of TBI. This study explored the role of long noncoding RNA (lncRNA) GAS5 in mice retinal ganglion cells (RGCs) suffered to H2O 2 injury.


The Living Clock The Orchestrator of Biological Rhythms. John D. Palmer. Oxford University Press, New York, 2002. 176 pp. $26, £19.99. ISBN 0-19-514340-X. Writing for nonbiologists, Palmer spices this informative overview of the natural history of biological clocks with anecdotes from his several decades of research on them.


The mammalian oocyte is a unique cell, and comprehending its physiology and biology is essential for understanding the fertilization, totipotency and early events of embryogenesis. Consequently, research in these areas influences the outcomes of various technologies, for example, the production and conservation of laboratory and large animals with rare and valuable genotypes, the rescue of the species near extinction, as well as success in human assisted reproduction. Nevertheless, even the most advanced and sophisticated reproductive technologies today do not always guarantee a favorable outcome. Elucidating the interactions of oocyte components with its natural partner cell - the sperm or an "unnatural" somatic nucleus, when the somatic cell nucleus transfer is used is essential for understanding how totipotency is established and thus to define the requirements for normal development. One of the crucial aspects is the stoichiometry of different reprogramming and remodeling factors present in the oocyte and their balance. Here, we discuss how these factors, in combination, may lead to the formation of a new organism. We focus on the laboratory mouse and its genetic models, as this specie has been instrumental in shaping our understanding of early post-fertilization events.


Three new species of oribatid mites belonging to the genus ELpidamaeus are described from Mongolia. Eipidamaeus granulatus sp. nov. differs from its closely related species in the presence of three setae en trochanter III, the strongly curved spinae adnatae directed anteromedially, and the very thick and strongly barbed notogastral setae. Iiipidamaeus cuttertsetosus sp. nov. can be distinguished from its congeners by the table-knife-like notogastral setae of the d, l, and h series; the dista11y expanded sensilli; the absence of prodorsal tubercles Da and Bp; the relatively long and distally projected tu-


Atmospheric deposition is a potential source of trace metals of continental origin to oceanic areas. Trace metals speciation (Fe, Al, Ca, Ti, V, Cr, Mn, Fe, Ni, Cu, Zn, Cd and Pb) was studied in atmospheric deposition (wet and dry) collected at a remote location in the Eastern Mediterranean Sea. Elemental concentrations were measured using ICP-MS, while Dissolved Reactive Fe (DSRFe: Fe (II) and Fe(III)) was determined spectrometrically. Atmospheric deposition was also compared with long-term trace metals data in sediment traps.