The invention discloses a method and a system for imaging a spectrum. The optical system comprises a space optical modulator generating a zone plate with different patterns, wherein a detector is arranged at the equivalent focal plane of the zone plate, and a diaphragm is arranged between a shooting target and the detector, so that the first stage of diffraction image generated by a fresnel zone plate can be acquired on the focal plane of the detector, and the other stages of the diffraction images not for acquiring can be filtered out. The method for imaging the spectrum comprises the following steps of: generating n zone plates with different patterns, and respectively focusing images with different wave lengths of the shooting target on the focal plane of the detector, to obtain the spectrum image with different wave lengths of the shooting target. After the building parameters of the zone plate are changed, the spectrum image with each waveband of scenery to be shot can be directly obtained on an appointed image surface without brooming in a pushing way. The system is simple to build, the aberration is easy to control, and the original spectrum data with each waveband of the scenery to be shot can be directly obtained, so that the data is high in fidelity.


Using stochastic quantization method we derive gauge-invariant equations, connecting multilocal vacuum correlators of nonperturbative field configurations immersed into the quantum background. Three alternative methods of stochastic regularization of these equations are suggested, and the corresponding regularized propagators of a background field are obtained in the lowest order of perturbation theory.


The discovery of rocky exoplanets relies on current detection limits of ground-based observational methods. Structural models of solid exoplanet interiors are constructed by using equations of state for the radial density distribution, which are compliant with the thermodynamics of the high-pressure limit. The modeling results imply that mass-radius relationships are robust and can be used to classify low-mass exoplanets such as CoRoT-7b and Kepler-10b in terms of their bulk compositions.


Abstract Poly(ethylene terephthalate) (PET) powder was depolymerized at atmos‐ pheric pressure in sulfuric acid in presence of 2.5 N phosphoric acid at 88–140°C. Particle sizes ranging from 50 to 512.5 µm and reaction time 30–200 min required for PET hydrolysis were optimized. Terephthalic acid (TPA) and ethylene glycol (EG) were produced by acid‐catalyzed heterogeneous PET hydrolysis. To avoid the carbonization/oxidation of EG and to reduce corrosion, reaction was undertaken below 150°C using less concentration of sulfuric acid at a lower reaction time. To enhance reaction rate, 2.5 N phosphoric acid was introduced during reaction. Ethylene glycol was recovered during hydrolysis by salting‐out technique. Terephthalic acid was separated out by using NaOH solution and then being acidified. Subsequently, TPA and EG were analyzed qualitatively and quantitatively. Yields of TPA and EG were almost equal to PET conversion. A modified shrinking‐core model based on obtained acid value of TPA explained depolymerization in sulfuric acid (in presence of phosphoric acid). Effective surface area is proportional to the degree of hydrolyzed PET (X), affected by formation and growth of pore and crack on PET powder. Hydrolysis rates as well as apparent rate constant are inversely proportional to particle size. Thermodynamics are also undertaken to determine activation energy, Arrhenius constant, equilibrium constant, Gibbs free energy, enthalpy, and entropy. Dependence of rate constant on reaction temperature was correlated by the Arrhenius plot, which shows an activation energy of 56.8 kJ mol−1 and a Arrhenius constant of 530.3 L min−1 cm−2.


Synchrotron radiation can potentially introduce large heat loads on the beam chamber of the superconducting undulator (SCU0) at the Advanced Photon Source (APS). With the photon absorber mask, a well-aligned centered beam in the upstream bending magnet allows only a small amount of radiation power, less than 1 W, to intercept the walls of the beam vacuum chamber in the cryostat, assuming no photon scattering. But beams with vertical orbit errors, especially, can deposit much higher heat loads on the beam chamber, above 100 W. An analysis was carried out to calculate the power on the vacuum chamber when the beam has an orbit error through the upstream bending magnet. This paper presents these analytical results compared to simulations that were performed using a 3D photon tracking code, Synrad3d.


Thin‐walled structures are used extensively in the passive safety of vehicles to absorb energy. The thin‐walled tube is already a traditional structure with excellent energy absorption. Negative Poisson's ratio (NPR) structures produce an inward concentration to increase the stiffness of the structure during axial compression. The concept of fluctuation of crushing force (FoCF) is introduced herein to evaluate this new energy‐absorbing box as an energy‐absorbing device based on the traditional energy absorption evaluation index. Based on experimental validation, a finite‐element model is developed that can accurately predict the crashworthiness of the double‐V NPR‐filled square tube (DVFST). The following parameters, such as out‐of‐plane thickness, meta‐cell half‐width beam thickness, and beam angle tube thickness, are conducted to assess the crashworthiness of the DVFST structure. The first thing that should be considered in the design of the DVFST structure is the half‐width of the cell, followed by the angle of the long beam, and then the relative wall thickness of the long and short beams. The DVFST structure has the potential to become an excellent energy‐absorbing device by adjusting its parameters.


This paper examines the benefits of navigating a crewed vehicle between the Earth and the Moon using both ground tracking and satellite-to-satellite tracking. Linked Autonomous Interplanetary Satellite Orbit Navigation (LiAISON) is a new technique that has been shown to dramatically improve the navigation of lunar satellites, libration orbiters, and Earth orbiting satellites using scalar intersatellite observations. In this paper, LiAISON is applied to the problem of navigating a crewed vehicle to the Moon. It has been found that LiAISON observations improve the navigation accuracy enough to reduce the number of active ground tracking stations from six to three.


In this article criminalization of arms trafficking in the Russian Federation is considered, the statistics of the Ministry of Internal Affairs of Russia is also given.


The vanilla fruit ( Vanilla planifolia Andrews) generates an important economic income; however, the best paid fruits are those of greater length (gourmet type), so strategies are needed to obtain fruits of that type. Given this, one option is the induction of metaxenia, understood as the increase in size of the fruits due to pollination with foreign pollen. In the case of vanilla, pollen of V. pompona Schiede could be used since it is usually a companion species, and its phenology coincides with that of V. planifolia . Cross-pollination between V. planifolia and V. pompona was performed during April 2021, and total length, diameter, weight and shape index were evaluated 40 days later. Influence of foreign pollen was found, manifested in longer and heavier fruits if the flower of V. planifolia was pollinated with pollen of V. pompona , while if the foreign pollen was from V. planifolia in flowers of V. pompona , the fruits were smaller and lighter. Cross-pollination between V. planifolia with V. pompona pollen is an alternative for producers to obtain gourmet-type fruits more easily.


This study focuses on elucidating the bond breaking steps involved in the electron beam induced deposition (EBID) of nanostructures created from the organometallic precursor cobalt tricarbonyl nitrosyl (Co(CO)3NO) by studying the effect of 500 eV incident electrons on nanometer scale films of Co(CO)3NO. Experiments were performed under ultrahigh vacuum conditions, using a suite of surface analytical techniques, principally X-ray photoelectron spectroscopy and mass spectrometry. The purely electron stimulated reactions of Co(CO)3NO adsorbed on gold or amorphous carbon substrates at low temperatures (−168 °C) occurs in two distinct steps. The first step involves a one electron process that initiates decomposition of the nitrosyl (NO) ligand to form a nitride, accompanied by the simultaneous desorption of at least one CO ligand to create a partially decarbonylated intermediate. This first step decomposes Co(CO)3NO into a nonvolatile Co-containing compound and therefore initiates the EBID process. In the seco...


A method and system are provided for testing a graphical user (GUI) (204). The method includes applying a test step (208, 222) to a GUI under test (204) and finding a control in the GUI under test (204) to which the test step is to be applied. A model (210) is built dynamically of representations of the contents of the GUI under test (204) as a new control is found. The method includes finding a collection of dependent controls and representing the collection of controls in the GUI model (210) as a generalised pattern of the controls. The method applies a test step to the model (210) simultaneously with the GUI under test (204) and compares the results of the test step from the GUI under test (204) and from the model (210). If a test step is applied to the model and it is determined that a representation of the control to which the test step is to be applied is not provided in the model (210), a building rule (212) is executed to add a representation of the control to the model (210). ® KIPO & WIPO 2009


In my thesis I will discuss the influence of the Old English poem Beowulf on J. R. R. Tolkien and his works. My focus will be on comparing the monsters of Beowulf to those of The Lord of the Rings, but I will also mention Tolkien's other works like The Silmarillion and The Hobbit. I will draw comparisons between Grendel and Gollum, Grendel's mother and Shelob, and the dragon of Beowulf and Sauron. As a special case,I will compare the dragon of Beowulf to that of The Hobbit because those two have the most in common. Tolkien's Smaug owes much to the dragon of Beowulf. I will use Vladimir Propp's Morphology of the Folktale as a theoretical background for a few interesting instances of a character playing two roles at once.
Furthermore, I will discuss Tolkien's essay The Monsters and the Critics in which he claims that monsters are the most important part of the epic poem as they demonstrate the
protagonist's physical strength and wisdom. Here I will explain how the weakest monster is fit for the beginning of the protagonist's warrior life, and how the strongest one is fit for the end of that life. The emphasis will be on the fact that the first monster stands for physical sin
and the last one for psychological sin. The weakest monster only seeks to satisfy its physical needs, such as hunger. The strongest one, on the other hand, seeks to satisfy psychological needs like greed and pride.
I will also mention how the monsters represent the evil side of heroic life, and how the fight against them is actually a fight which the hero leads against himself. There is good and bad in every hero and by defeating the monsters, he defeats the bad side of his own self which, in turn, makes him a well-respected warrior. Thus every fight described in Beowulf represents a psychological victory of the protagonist's good side, which makes him a better warrior and later king. Tolkien transferred that same inner fight into his stories.


Higher education in Ukraine has found itself in new realities, and the national market of educational services has obtained completely new features of the competitive environment, which combine the results of integration processes and socio-political factors derived from the martial law. As a result of military actions, temporarily relocated higher education institutions (HEIs) emerged as a special category in the market of educational services. The aim of the paper is to study the problems and needs of temporarily relocated HEIs and internally displaced persons, as participants of the educational process, under their integration into the competitive environment of the educational services market. The author determined that for HEIs a study (degree) programme is the main product presented on the market. The primary indicator of the competitiveness of study programmes is the demand declared by entrants to the first (bachelor's) level of higher education. Trends in the formation of a competitive environment in the market of educational services were analysed based on the results of the admission campaign. It was defined that the tendency for Kyiv and Lviv universities to hold the leading positions in most study programmes was preserved. The article presents a comparative analysis of the dynamics of the main competitiveness indicators for study programmes, being most popular among entrants, in HEIs identified as leaders in terms of the number of applications and in temporarily relocated HEIs. The relocated HEIs are facing a particularly acute problem with filling the licensed number of students. Based on the admission results of 2022, a part of relocated universities enrolled only as many students as to fill the positions funded by the state. Temporarily relocated HEIs and internally displaced research and pedagogical staff need additional social protection tools and special support and assistance in resuming full-fledged activities from host communities, local self-government bodies, the government and international organizations.


Messages in a communication process can influence a person in making decisions, whether or not to perform certain behaviors. One of the important things to study is how the community treats their environment. This study aims to analyze how the use of message frames in building an environmentally friendly community and how the level of environmentally friendly behavior in the community. The location of this research is in a densely populated communities in the city of Bogor, namely Pulo Geulis which is located in the middle of the Ciliwung river. Data collection and analysis has been carried out since 2019 using a research instrument in the form of a questionnaire. The results showed that the types of message frames used in building environmentally friendly behavior were benefit messages, risk messages, and technical messages. The level of environmentally friendly behavior of Pulo Geulis residents is at the level of "environmentally friendly enough" at a percentage of 81%.


BACKGROUND: The increased survival rate among individuals with congenital heart disease (CHD) has sparked interest in their transition to adult healthcare. Although there is a general agreement on the importance of transition interventions, the empirical evidence supporting them is insufficient. Therefore, this study aimed to conduct a systematic review and meta-analysis of transition interventions for adult healthcare in adolescents and young adults. METHODS AND RESULTS: A literature search was conducted for studies comparing the quantitative effects of transition interventions with control groups, published up to March 15, 2023, in major databases (CENTRAL, Embase, PubMed, Web of Science, CINAHL, KISS, and KMbase), major clinical trial registers, academic journal sites related to the topic, and grey literature databases. Ten studies involving a total of 1,297 participants were identified. Transition interventions proved effective in enhancing disease-related knowledge (Hedge?s g=0.89, 95% CI=0.29-1.48) and self-management (Hedge?s g=0.67, 95% CI=0.38-0.95), as well as reducing loss to follow-up (OR=0.41, 95% CI=0.22-0.77). The certainty of evidence for the estimated values of each major outcome was low or very low. CONCLUSIONS: This study supports the implementation of transition interventions by demonstrating that they can improve patients' disease knowledge and self-management, while also promoting treatment continuity. However, since the available data on transition interventions for adolescents and young adults with CHD remain limited, the widespread adoption of structured transition interventions in the future may alter the conclusions of this study.


Embryogenic callus cultures of Korean native Seosanjong of ginger(Zingiber officinale Rosc.) were induced through stem explants taken from in vitro shoot-tip cultures. Among the four concentrations of 2,4-D tested in Murashige and Skoog medium, 0.5 and 1 ㎎/L of 2,4-D was most effective in inducing embryogenic callus. Leaf explants did not express any new morphogenetic response in all 2,4-D concentrations tested. Plantlets transferred to hormone-free MS medium were developed and successfully acclimatized under greenhouse.


The purpose of this Cooperative Research and Development Agreement (CRADA) between Lockheed Martin Energy Research Corp., (LMER), Argonne National Laboratory (ANL), National Renewable Energy Laboratory (NREL), and Battelle Memorial Institute, operator of Pacific Northwest National Laboratory (PNNL), (collectively referred to as the 'Contractor'), and Applied Carbochemicals, Inc. (Participant) was to scale-up from bench results an economically promising and competitive process for the production of chemical derivatives from biologically produced succinic acid. The products that were under consideration for production from the succinic acid platform included 1,4-butanediol, {gamma}y-butyrolactone, 2-pyrrolidinone and N-methyl pyrrolidinone. Preliminary economic analyses indicated that this platform was competitive with the most recent petrochemical routes. The Contractors and participant are hereinafter jointly referred to as the 'Parties.' Research to date in succinic acid fermentation, separation and genetic engineering resulted in a potentially economical process based on the use of an Escherichia coli strain AFP111 with suitable characteristics for the production of succinic acid from glucose. Economic analysis has shown that higher value commodity chemicals can be economically produced from succinic acid based on preliminary laboratory findings and predicted catalytic parameters. At the time, the current need was to provide the necessary laboratory follow-up information to properly optimize, design and operate a pilot scale process. The purpose of the pilot work was to validate the integrated process, assure 'robustness' of the process, define operating conditions, and provide samples for potential customer evaluation. The data from the pilot scale process was used in design and development of a full scale production facility. A new strain, AFP111 (patented), discovered at ANL was tested and developed for process use at the Oak Ridge National Laboratory (ORNL) and ANL. The operability and product formation are attractive for this strain and effort was being directed at process development and optimization. Key to the transition from the fermentative production unit operation to the chemical catalysis is the 'clean-up' of fermentation broth, succinic acid formation from the salt, and succinic acid concentration. These steps are accomplished by a two-stage membrane ED separation process developed at AWL. Although the current process is well developed, possible modifications and optimization may be called for as development work continues in both the fermentation and catalysis areas. Research to date performed at PNNL has demonstrated that succinic acid can be converted to value added chemicals such as 1,4-butanediol, {gamma}-butyrolactone, N-methyl pyrrolidinone, and 2 pyrrolidinone with high conversion and selectivities. Continued research will be performed in catalyst development and reaction condition optimization to move this work from the bench scale to the pilot scale. All development of the process was guided by the NREL technoeconomic model. The model showed that direct aqueous phase catalysis of succinic acid to 1,4-butanediol, {gamma}-butyrolactone, and N-methyl pyrrolidinone provided significant economical advantages in the market, the margin, and the return on capital investment over existing petrochemical processes for production of these compounds. The model also provided the baseline for evaluating current laboratory research. As data from the bench and pilot work were made available the model was modified and appropriate sensitivities ran to determine impact of the process changes and optimization. The report will present the planned CRADA tasks followed by the results. The results section has an overall project summary follwed by more detailed reports from the participants. This is a nonproprietary report; additional proprietary information may be made available subject to acceptance of the appropriate proprietary information agreements.


This article examines how definitions of `healthy' and `unhealthy', `appropriate' and `inappropriate' computer use are produced and mobilized by and through very specific American cultural ideals and interests. Following Foucault (1978) and Rose (1990, 1998), this article explores how the discourse on pathological computer use functions as a normalizing discourse — and as an apparatus of governance — by mapping correlations `between fields of knowledge, types of normativity, and forms of subjectivity' in a particular context (Rose, 1998: 11). The article describes the historical management of computer fear and addiction, and the formation of the `computerphobe' and `computer addict' as products of a specific historical milieu. For example, the convergence of American (sub)cultures such as the drug counterculture, cyberpunk technoculture, and the `culture of addiction' functioned as the conditions of possibility for the cultural intelligibility of `computer addiction'. At the same time, the article illustrates how computer use pathologies have been produced and mobilized toward the production and management of people's developing relationships with this new media technology, even while it defines and produces — or governs — related definitions of `appropriate' and `inappropriate', or `normal' and `abnormal', social practice such as commercial property and labor efficiency.


The formation of an integrated radionavigation field on the basis of existing ground-based and satellite radionavigation systems is considered, along with applications of this field in integrated airborne receivers.


The purpose of this study was to identify the needs of marriage education programs for multicultural couples based on their socio-demographic characteristics. A total of 816 multicultural families (247 Korean husbands and 569 foreign wives) were recruited through 99 Multicultural Family Support Cent...


This student poster paper presents an innovative practice in order to increase the scalability and efficacy of student problem-based team learning in large enrollment engineering classrooms. We have devised a novel Virtualized Active Learning (VAL) approach to facilitate instructional delivery, assessment, and review of teams. VAL introduces a new pathway by utilizing open-source digital environments for effective and scalable teambased learning in classroom settings while empowering equitable participation from diverse learners. The proposed method provides a unique opportunity for learners to acquire knowledge and skills that are considered vital in STEM fields such as working in multidisciplinary teams proficiently and communicating with other team members in an effective manner. Meanwhile, they are engaged in finding an optimal solution to a design problem that requires certain specific constraints to be adequately met. The results of our pilot study indicate excellent potential for VAL in large enrollment STEM courses while facilitating the instructors to provide assistance and feedback to students in real-time.


A 54‐year‐old man showed evidence of disease progression and a reduction in donor chimaerism by molecular microsatellite analysis 6 months after an allogeneic peripheral blood stem cell transplant for chronic idiopathic myelofibrosis. He was treated with a single infusion of donor leucocyte infusions (DLI), which led to the development of mild acute graft versus host disease (GVHD) and the rapid restoration of full donor haemopoiesis. This subsequently led to a progressive reduction in marrow fibrosis from grade IV to grade I over the following 6 months. We believe that this is the first report to provide clear evidence for the efficacy of DLI in this setting, which also provides evidence for the existence of a T‐cell‐mediated 'graft vs. myelofibrosis' effect similar to that seen against other haematological malignancies.


Background : Female Sexual Dysfunction (FSD) is a disturbance or dysfunction in the process of desire, arousal or orgasm which can be a symptom of a biological condition, a psychological problem or an interpersonal issue or a combination of these factors. Female Sexual Dysfunction is a multi-causal and a multi-dimensional medical problem that adversely affects physical health & emotional wellbeing. Also impaired sexual function has damaging effects on the self esteem, sense of wholeness and interpersonal relationships of women. It is often emotionally distressing and might lead to familial discord and divorce, and reproduction is also affected. Sildenafil is selective type 5 phosphodiesterase (PDE5) inhibitors , taken orally and effective for men with erectile dysfunction. Previous studies suggested that sildenafil, which acts by inhibiting cyclic GMP specific PDE5, may improve the sexual health of women affected by sexual difficulties such as arousal disorders and may indirectly improve other aspects of sexual life. Sildenafil was effective and well tolerated in post menopausal women with sexual arousal disorder without concomitant hypoactive sexual desire disorder or contributory emotional relationship or historical abuse issues. Objective: This study aims to evaluate the effect of sildenafil citrate on female sexual dysfunction. Subjects and Methods: The study was conducted in Dermatology,Venereology, and Andrology department, Faculty of Medicine, Zagazig University Hospitals during the period from April 2015 to August 2016. Twenty six married female patients were included in this study. Patients were divided into two groups. Group 1 contains thirteen patients took 50mg sildenafil on demand and group 2 contains thirteen patients took placebo. Results: There was no significant differences between the studied groups regarding the demographic data, and FSFI scors. There was significant differences between pre and post treatment of sexual dysfunction scors regarding group І. There was no significant differences in post treatment results between the two studied groups as regard sexual dysfunction except in orgasm and pain. Conclusions: Sildenafil citrate may be effective in women who couldn't achieve orgasm and decrease pain in patients with dysparunia.


Objective To improve synthetic process of alogliptin benzoate. Methods Alogliptin benzoate was synthesized from 6-chlorine uracil and iodomethane to give 3-methyl-6-chlorine uracil,then in the presence of inorganic base with 2-bromine methyl benzonitrile reaction to 2-(6-methyl chloride-3-2,4-dichloro generation-3,4-dihydro-2 h-pyrimidine-1-methyl)-benzonitrile,which was subjected to displacement with(R)-3-aminopiperidine in the presence of inorganic base. And then salified with benzoic acid to obtain alogliptin benzoate. Results Alogliptin benzoate was synthesized. The overall yield was 57. 09%,and its purity was 99. 6%. Conclusion The improvement reduced toxic,and was economic and environmental. It was suitable for industrial production.


The purpose of this study is to analyze the policies and practices of schools in Japan that serve large numbers of bilingual students. Using the notion of imagined communities (Anderson, 1991; Norton, 2001), I examine the relationship between the schools' visions for their students, their current policies and practices, and the students' identities. Based on the ethnographic data collected at four schools in Japan that cater to very different groups of bilingual children, I argue that schools have visions of the communities and societies in which their students will grow up to participate. Moreover, these visions condition the schools' current policies and practices and ultimately affect the identities of the students. Because the students at the four schools are expected to lead different futures, they are being prepared for different kinds of bilingualism. In this stratification process, it is the least privileged bilingual children who are socialized into the most impoverished imagined communities.


e14705 Background: The addition of bevacizumab to chemotherapy significantly shows survival advantage in metastatic colorectal cancer (mCRC), but with limited data about irinotecan combination in salvage therapy. Efficacy and toxicity of bevacizumab combination regimens were assessed in first-line and salvage therapies. Methods: Total of 1011 (659 in first-line and 352 in salvage) patients were retrospectively evaluated. Results: In first-line therapy, the ORR was 36.4%. Median PFS was 7 months for FOLFIRI, 6 months for IFL and 6 months for other chemotherapy regimens with a median overall PFS of 7 months. Median survival was 29 months for FOLFIRI, 28 months for IFL and 21 months for others with a median overall survival of 28 months. In salvage therapy, the ORR was 25.2%. Median PFS was 7 months for FOLFIRI, 7 months for IFL and 6 months for others with a median overall PFS of 7 months. Median survival was 19 months for FOLFIRI, 13 months for IFL and 21 months for others with a median overall survival of...


This article looks at the factors leading to the recent call for a referendum against the new municipal boundaries in Macedonia to highlight some of the main challenges to the stabilisation of interethnic relations in the country after the signing of the Ohrid Agreement. It argues that the democratic deficiencies which marked the first 10 years of transition are still capable of producing ethnic tensions, thus putting the country's stability at risk. This analysis reveals that the international community— largely responsible for overcoming Macedonia's security crisis of 2001—still acts as a security provider, indispensably intervening in domestic affairs to counter new threats to interethnic coexistence. I argue that stability in Macedonia can only be sustainable after the democratic deficits of the system are addressed, and suggest that a positive step in this direction would be for the international community to reconsider its approach to the political situation by changing its current practice of putting pressure on the government to blindly implementation the Ohrid Agreement and by providing aid towards the arduous process of democratisation.


A driving support system for giving a support to a driving operation of a vehicle includes a drive history database and a drive teaching unit for specifying a travel route of a vehicle subjected to a driving support. Vehicle information including information about vehicle operation is associated with pertinent route information and is registered as a drive history in the drive history database. The drive teaching unit is configured to extract a drive history corresponding to the specified travel route from the drive history database. The drive teaching unit is further configured as a guide for the driving support to teach information about the extracted drive history to a driver of the vehicle subjected to the driving support.


Ethereum is a decentralized Blockchain system that supports the execution of Turing-complete smart contracts. Although the security of the Ethereum ecosystem has been studied in the past, the network layer has been mostly neglected. We show that Geth, the most widely used Ethereum implementation, is currently vulnerable to eclipse attacks, effectively circumventing recently introduced security enhancements. Our false friends attack exploits the Kademlia-inspired peer discovery logic used by Geth and enables a low-resource eclipsing of long-running, remote victim nodes. An adversary only needs two hosts in distinct /24 subnets to launch the eclipse, which can then be leveraged to filter the victim's view of the Blockchain. We discuss fundamental properties of Geth's node discovery logic that enable the false friends attack, and propose countermeasures.


An average medium-sized organisation logs approx. 10 to 500 mln events per day on the system. Only less than 5% of threat alerts are being investigated by the specialised staff, leaving the security hole open for potential attacks. Insufficient information in alert message produced in machine-friendly rather than human-friendly format causes cognitive overload on currently limited cybersecurity resources. In this paper, the model that generates the report in natural language by means of applying novel storytelling techniques from security logs is proposed. The solution caters for different levels of reader expertise and preference by providing adjustable templates, filled from both local and global knowledge base. The validation is performed on case study from Security Operations Centre (SOC) at educational institution. The report generated proves superior to existing approach in terms of comprehension (increased cognition) and completeness (enriched context). The evaluation demonstrates power of storytelling in potential threats interpretation in cybersecurity context.


The estimation of photosynthetic potential of rice can reflect the upper limit of its potential of production, and it is of great significance to improve the yield of grain per unit and ensure the security of grain in the future. From the point of view of solar radiation and sunshine hours, the photosynthetic potential of rice in 24 meteorological stations in Liaoning Province during the growth period from May to September was estimated by using Huang Bingwei theory. The results show that: during the study period, the average photosynthetic potential productivity of rice in Liaoning province was 25168 kg·hm -2 , which showed a decreasing trend over time and the decreasing rate was 39.25kg·hm -2 ·(10a) -1 .The spatial variation shows a trend of high in the northwest and low in the southeast.


The invention concerns a regulator for a three-phase current generator, wherein the generator phase voltage is evaluated. Said phase voltage is evaluated by means of a range comparator with variable thresholds. A signal (VCL), switched at each threshold adaptation, enables to produce a signal which is a function of the frequency and can be evaluated as measurement of the generator operating conditions.


This paper seeks to offer an interpretation of the significance of the core of education in an attempt to achieve public policy goals. Some publications addressing approaches, techniques, and models of learning as a means of understanding the ideal education, but there are still deficiencies attributable to educators or adults who do not see the environment as a place of training. The paper aims to provide parents, teachers, and the community with knowledge so that education is a joint obligation so that cooperation in the education system is complete. "Tri Pusat Pendidikan" are three critical elements that play an essential role in learning and become the center of educational activities, namely family education (informal education), school training (formal education), and social education (non-formal culture). The "Tri Pusat Pendidikan" idea means that learning can be done anywhere and at any time, being a mutual obligation. This principle says the society and family have a balanced responsibility for the success of education offenders, and that it is not just schools that are made and regulated as organizations that have a great (full) responsibility for the success of individuals in their educational cycle.


The contribution introduces the notion of framelets. They are essentially small frameworks. Thus framelets can be easily understood and modified. As framelets are not aimed at complex application domains, they can also be assembled without the problems associated with the combination of large frameworks. Our first experiences with framelets demonstrate that these architectural building blocks allow the integration of framework technology into legacy applications. Furthermore, framelets might form a suitable means for structuring software architectures. 1 Frameworks and legacy applications Conventional wisdom implies that legacy applications and framework technology do not match well. Framework experts usually advise the development of a domain-specific architecture for the domain at hand. The legacy application would have to be replaced by the adapted framework. Most companies are not willing to pursue such a radical approach, which renders the investments into legacy applications worthless. Furthermore, the development of a complex framework from scratch represents a formidable risk. The brilliant architects who would be able to design domain-specific frameworks are often not available. This situation forms the starting point of our considerations, i.e., how framework technology can be harnessed in the realm of legacy applications. The legacy system at hand is a client/server application of a bank. Our approach is straight-forward: Taking a look at the overall conventional system architecture and then at the underlying source code reveals that some quite small aspects of the system are implemented numerous times again and again in a similar way. For example, the legacy application relies on remote procedure calls (RPCs) implemented in C. The code associated with a particular RPC implies tedious programming work, in particular handling the parameter value transfer for each RPC. For example, the return parameter types are C-style arrays, which have to be properly processed. The RPCs are too diverse to come up with a simple reusable procedure/function. Instead we found that a small framework is the solution in order to automate the calling of remote procedures. The hot spot of the RPC framelet is the processing of parameters. Another example of reimplemented code can be found at the client side of the legacy system. Most dialogs provide one or more list boxes (a.k.a. grid controls) together with buttons to add items to the list box, and to modify and remove them. Thus these GUI elements and their interactions have to be implemented again and again. The associated programming task is another typical example of a piece of programming work that can easily be packaged into a small self-contained framework. The hot spot of the so-called list box framelet is the dialog, which displays an item. Figure 1 shows a sample specialization of the list box framework. The dialog on the left-hand side consists only of the framework's GUI and the button labeled Close. The arrows in Figure 1 indicate the interactions between the framework components.


THE preservationof health, particularly at the presenttime, is an economicas much as a medical problem. It dependslargely on an adequatesupply of suitable nourishment. Continuedunder-nourishment is hard enough on the strong and healthy; it is gravely dangerous to the very young, the weak, the sick, those with latent diseaseet cetera. Every medical ー イ 。 セ エ ゥ エ ゥ ッ ョ セ N ヲ has seen its effects, whether or not he has re.cognized them as such. The rates of invalidity and mortality among these under-nourished people must have been higher during the pastfew yearsthan they would normally have been; but they are unlikely to have been as high among セ カ ・ イ 。 ァ ・ Australians as among the people of slums in the dim and often fog-begrimed cities of some other countries. The influence of poverty and malnutrition on the health of a section of the inhabitantsof an English industrial town is discussedin a recentinterestingcommunicationby G. C. M. McGonigle, the Medical Officer of Health at Stockton-on-T'ees.! In 1927 an unhealthy area (known as the Housewife Lane area) in the town of Stockton-on-Teeswas demolished and its 710 inhabitants were moved to the Mount Pleasant area, consisting of modern houses specially built by the municipalauthorities. "From a hygienic and environmentalpoint of view the new estateappears to be everything that modern sanitary sciencecan demand." Another unhealthy area (Riverside), with 1,298 inhabitants,remaineduntouchedby the hand of progress; it served as a suitable control area. A study of the vital statisticsrevealedthe surprising fact that "the mean crude death rate per rnille in the Mount Pleasantareafrom 1928 to 1932 was 26'71 per anl1J1Mn, though from 1923 to 1927 it had been18'75 in the HousewifeLane area; from 1923 to 1927the mean rate in the Riverside areawas22'16, and from 1928 to 1932,20'45; during the sameperiods the mean rates for the whole of the town were 13'96 and 13·28 respectively. The mean standardizeddeath rates were even more remarkable, rising from 22'91 pe-r mmUln in the Housewife Lane area during the period 1923 to 1927, to 33'55in the Mount Pleasantarea during the period 1928 to 1932; at the sametime the rates for England and Wales, Durham County and Stockton-on-Teesdecreasedslightly, while the rate for the Riversideareadecreasedfrom 26'10 to 22'78.


We present a study of the outflowing ionized gas in the resolved narrow-line region of the Seyfert 2 galaxy Mrk 573, and its interaction with an inner dust/gas disk, based on Hubble Space Telescope (HST) Wide Field Planetary Camera 2 and Space Telescope Imaging Spectrograph observations. From the spectroscopic and imaging information, we determined the fundamental geometry of the outflow and inner disk, via two modeling programs used to recreate the morphology of these regions imaged with HST. We also determined that the bicone of ionizing radiation from the active galactic nucleus intersects with the inner disk, illuminating a section of the disk including inner segments of spiral arms, fully seen through structure mapping, which appear to be outflowing and expanding. In addition, we see high velocities at projected distances of ⩾2″ (∼700 pc) from the nucleus, which could be due to rotation or in situ acceleration of gas off the spiral arms. We find that the true half-opening angle of the ionizing bicone (53°) is much larger than the apparent half-opening angle (34°) due to the above geometry, which may apply to a number of other Seyferts as well.


The Rowntree management conferences are a unique repository of thinking about management in general and British management in particular. Held over a span of nearly twenty years, they encapsulate a certain strand in management thought that, unlike many other contemporary management theories, was liberal, human-centred and forward-looking. They are an experiment – tried once and never really repeated – in trying to carve out a peculiarly British approach to management thinking and practice.


Lasing at extremely low pump intensities, below 1 mW, and dramatically enhanced Raman scattering were observed for a novel class of optical materials, microcavities doped with nano‐structured fractal aggregates. Nanostructured fractal aggregates lead to giant local‐fields concentrated in "hot spots" much smaller in size than the size of the fractal and the wavelength. Coupling the localized plasmon modes in fractal aggregates with microcavity resonances further increases the local fields. These microcomposites possess unique optical characteristics, including extremely large probabilities of radiative processes. An extremely pronounced time‐dependent lasing effect of dye molecules adsorbed on silver particles was also observed in our experiment This time dependence is likely due to photo‐stimulated aggregation of silver colloid particles and the gradient forces pulled fractal aggregates into the high‐field area associated with the morphology‐dependent resonance mode.


In this paper,we use Harris operator to extract image corners.Then we use the NCC operator to get the rough matching pairs.Last we use Ransac matching algorithm to get Picked matching pairs.But in matching process,the existence of situation of mismatch,we improve target tracking method based on corner matching,calculate the corner offset the mean square error method,excluding the larger point of the offset,taking match better the first few match points to compute the mobile position of the current window.


Stress is a major problem of the modern world, causing psychological and physiological diseases. Object of this study was to evaluate the effects of cognitive behavioral therapy on coping styles of non-medical students of Shahrekord university of medical scences. This two phases experimental study was performed on 60 students, having non-effective coping styles. They were randomly divided into the control (n=30) and case (n=30) groups. Billingz & Mouse coping questionnaire was used to assess coping styles. The case group was treated with 8 weeks of group cognitive behavioral therapy. Quantitative analysis of data was undertaken by using dependent and paired t-tests. The results showed that cognitive behavioral therapy had significant effects on improvement and effectiveness of the coping strategies (P<0.001).


The objective of this study was to analyse retrospectively the clinical and pathologival data of 147 patients with primary presacral tumor from 1954 to 2004.The results showed: that the main diagnosis approaches of the primary presacral tumors were anoscopy, ultrasonography (USG) and computed tomographic(CT). The pathological types of primary presacral tumors were complex. As to the data, there were 30 different pathological types revolved, and among them, 49.7% were benign and 50.3% malignant respectively.The main therapy was surgical resection. In the data, the tumor was completely resected in 77 cases;partially resected in 32 cases; secondary operation was completed in 18 cases. A total of 78 cases were treated by surgery combined with radiotherapy, chemotherapy or immunotherapy.The effect of integrative therapy was depended on the histological type, the volume of the tumor and so on. The life span of the patients were from 3 months to 14 years and the median survival term was 2 years. The main influencing factors were the histological type, the resected rate of the tumor, the application of integrative therapy.


The teacher-scholar model was created in recognition of the expectations that university faculty members will engage in both high-quality teaching and scholarship. The adoption of the teacher-scholar model at universities has been mixed. Our exploratory case study investigation took place at a primarily teaching university in which the model was recently embraced. We wanted to empirically document the faculty members' knowledge, perceptions, preparation, and engagement in the teacher-scholar model. Our results indicate that the faculty members held constrained levels of knowledge of the model, were neutral in their perceptions of model, had a range of preparation to productively engage in the model, and they tended to take an array of approaches for engaging in the model. We also found positive relationships among perceptions of the teacher-scholar model, knowledge of the model, faculty member engagement in scholarship, and the duration of employment in higher education. Our findings suggest that there is a need for long-term professional development focused on the teacher-scholar model at universities where the model is being adopted.


Deforestation and habitat loss are widely expected to precipitate an extinction crisis among tropical forest species. Humans cause deforestation, and humans living in rural settings have the greatest impact on extant forest area in the tropics. Current human demographic trends, including slowing population growth and intense urbanization, give reason to hope that deforestation will slow, natural forest regeneration through secondary succession will accelerate, and the widely anticipated mass extinction of tropical forest species will be avoided. Here, we show that the proportion of potential forest cover remaining is closely correlated with human population density among countries, in both the tropics and the temperate zone. We use United Nations population projections and continent‐specific relationships between both total and rural population density and forest remaining today to project future tropical forest cover. Our projections suggest that deforestation rates will decrease as population growth slows, and that a much larger area will continue to be forested than previous studies suggest. Tropical forests retracted to smaller areas during repeated Pleistocene glacial events in Africa and more recently in selected areas that supported large prehistoric human populations. Despite many caveats, these projections and observations provide hope that many tropical forest species will be able to survive the current wave of deforestation and human population growth. A strategy to preserve tropical biodiversity might include policies to improve conditions in tropical urban settings to hasten urbanization and preemptive conservation efforts in countries with large areas of extant forest and large projected rates of future human population growth. We hope that this first attempt inspires others to produce better models of future tropical forest cover and associated policy recommendations.


Issues in multimedia networking over the fiber distributed data interface (FDDI) and simulation results demonstrating the feasibility of multimedia over FDDI are discussed. Previous work in this field has concentrated on the asynchronous channel in FDDI. Other examinations of the FDDI synchronous channel have applied bursty traffic to the synchronous channel. Multimedia traffic is typically stream oriented. The simulations reported were focused on simulating typical configurations with a range of applications and traffic models. The advantages of FDDI as an integrated voice/video data network are demonstrated.<<ETX>>


The double-ended queue involving taxis and customers at a taxi-stand has been considered under the assumption that there is limited waiting space both for customers and for taxis, and that the taxis "serve" the customers in bulk. The arrivals of customers and taxis are taken as general and Poisson respectively. Two separate probability generating functions have been defined for the cases when i taxis are waiting and ii when customers are waiting and their Laplace transforms L.T.'s as well as that of the probability for empty state have been obtained by using the supplementary variable technique. Cases of Erlangian and Poisson arrivals of customers and of single-seated taxis are considered as particular cases.


Currently, lithium-ion batteries (a type of secondary battery) are used as the primary sources of power in many applications due to their low energy loss as a result of their high energy density and low self-discharge rate, and their ability to store energy for a long time. However, due to the frequent charging and discharging of such batteries, overcharging is inevitable. This can cause system shutdowns, accidents, or property damage due to explosions. Therefore, it is necessary to accurately predict the state of charge (SOC) of batteries for stable and efficient usage. Hence, in this paper, we propose a SOC estimation method using a vehicle driving simulator. After manufacturing the simulator to perform the battery discharge experiment, voltage, current, and discharge-time data were collected. Using the collected data as input parameters for an RNN-based LSTM, we estimated the SOC of the battery and compared the errors to. We then used the developed LSTM surrogate model to conduct discharge experiments and simultaneously estimate the SOC in real-time.


This chapter has three aims (i) it introduces the reader to the evolutionary puzzle of cooperation: why it is relatively rare despite its potential profits; (ii) it offers an account of the transition from the dominance-structured social world of the great apes and earliest hominins to a much more egalitarian and cooperative social order of the small mobile forager band of early to mid-Pleistocene hominins. Their cooperation mostly took the form of immediate return mutualism, and the chapter explains why this form of cooperation is more easily stabilized that reciprocation-dependent cooperation. (iii) It then offers an account of the transition from immediate return mutualism to cooperation through reciprocation: more efficient, potentially more profitable. But less inherently stable. The chapter connects the expansion of cultural learning to the stability of cooperation based on reciprocation.


Advances in computational capacity made available through graphics processing unit (GPU) processing and developments in parametrically driven design tools are creating new possibilities for acoustic design and analysis. In particular, wave-based numerical simulations are becoming more tractable, and geometry manipulations, which were once cumbersome manual work, can now be automated. A case study of concert hall section profile optimization is presented. Using RHINOCEROS software with the GRASSHOPPER parametric modeling plugin, geometries were automatically generated based on a few parameters, then evaluated using Finite Difference Time Domain (FDTD) numerical simulations using GPU processing in MATLAB. The results from each iteration are used to inform a global optimization algorithm that conducts an intelligent search of the parameter space to find a solution in as few iterations as possible. The optimization is based on a stochastic model of the multidimensional objective function. The objective function is iteratively sampled and a simplified Bayesian approach is used for finding the set of parameters which is most likely to improve the current estimate of the global minimum at each iteration. With this method, curved and linear iterations of the sidewalls and under-balcony surfaces of a concert hall section were investigated. The objective was to deliver the most early energy, in the most uniform distribution, from multiple sources to multiple receiver positions.


Objective:To establish a determination HPLC method for miconazole nitrate in miconazole nitrate sup- positories and raw material.Method:HPLC was applied with ZORBAX Eclipse XDB -Cscolumn(4.6 mm×150 mm,5μm),and the mobile phase of 0.02 mol·L~(-1)disodium hydrogenphosphate dodecahydrate solution-metha- nol(15:85),and the detection wavelength was 230 nm.Its contents were determined with external standard meth- od.Results:The linear response range of econazole nitrate was 0.0102-0.4074 mg·mL~(-1)(r=0.99982).The mean recoverise was 99.68%(n=9),RSD=1.20%.Conclusion:This method is accurate with good reproduc- ibility,can be used for quality control standard of miconazole nitrate suppositories.


The present invention describes a method and measurement system imbalances in an electrical network. The method comprises the steps of obtaining effective values and arguments of the voltages and currents of the phases at the fundamental frequency; calculating the effective value and the argument of positive sequence voltages and effective values of negative sequence voltages; determine the active and reactive of each of the phases at the fundamental frequency powers; and calculate the value of the imbalance power vector according to the following equation: # **** **** # IMAGE-01 where {} = 1 to <120 °; j is the imaginary unit; {De} {sub, U} = V {sub, -} / V {sub, +} and {de} {sub, A} = V {sub, 0} / V {sub, +} is the degrees of imbalance and tailing, respectively, of the phase voltages; and (vector p), (q vector), (vector z) are orthogonal unit vectors that define the eigenspace vector imbalance power.


Semiconductor application equipment has been widely used by rapid advance of the power electronics technology, and the voltage distortions in power systems have increased and, therefore, the harmonics have become problems recently. As for the equipment that has semiconductor applications, it is possible that the use would be increased in the future, and the harmonics troubles would be increased correspondingly. In order to solve the problems, this paper proposes an optimal filter allocation method using a nonlinear programming technique. Simulations results are given for 6 and 20 bus systems to illustrate and verify the proposed method.


At a meeting entitled an Institute on Medical Education and Family Planning the speaker F.C. Robbins Dean of Case Western Reserve University School of Medicine commented on a number of issues related to population control. Population growth must be brought into equilibrium at or below zero. The effects of overpopulation are evident today. On the basis of many animal experiments one can confidently expect that as crowding becomes more serious diseases both organic and emotional which are associated with chronic stress will appear. Increased food production can be no more than palliative and by making possible further population increase tends to reduce the time required to pass from an acceptable standard of living to famine. The present emphasis upon family planning which relies upon education individual motivation freedom of choice and voluntary participation while appropriate to the needs of individuals cannot realistically be expected to lead to the rapid and drastic reduction in world birth rate that is needed to prevent major famine and misery. Adequate control of reproductive rates will require some form of coercion.


Aiming at the current shortcoming of relying on online control of process parameters in hot rolling process, we proposed a digital twin model based on CGAN. This model can simulate the rolling process according to rolling information such as production conditions, working environment, material properties, and rolling sequence. For model training, testing and validation, we collected actual production data of the hot rolling mill is collected. The results show that the process parameters generated by the model are close to those of the real process, which proves it can reflect the hot rolling process and could be used for future simulation, quality prediction and production optimization of the hot rolling process.


Aiming to propose strategies for breeding an intraspecific hybrid of Oreochromis niloticus with high performance and red colouring, were performed backcrossing, with Red Stirling parental and Chitralada varieties, containing 50%, 75% and 87.5% of genic proportion of Chitralada variety. Experiments were performed in the Indústria Brasileira de Peixe Ltda in Itupeva, State of São Paulo. For the nursery phase, the randomized complete block design with four replications of seven genetic groups were used, namely, Chitralada (C) and Red Stirling (R); the hybrids F1, fish-female Red Stirling × fish-male Chitralada (RC) and its reciprocal (CR); the backcrossing (RC1), fish-female CR × fishmale Chitralada (CR×C) and its reciprocal (C×CR); and the recurrent backcrossing RC2 [C(C×CR)]. Progenies were distributed in 28 hapa 1×1×1m containing 100 fish each, for 90 days. After they could weight at least 15g, 15 fish-females and 15 fish-males were collected from each parcel. Fish were identified by using electronic chips classified according to their weight and allocated in 8 net cages, four for fish-female and another four for fish-males, one for each weight class. Biometry was carried out each 21 days until completing 190 culturing days. Values of heterosis, maternal heterosis, paternal heterosis, general combining ability, specific combining ability, maternal effects for weight and for length, were calculated. For the nursery phase, the logistic model was adjusted. However, there was no significant statistical differences among the parameters A, B and K of the model. The growth was different between fish-males and fish-females in the second phase, on which the adjusted model was the exponential. For the fish-males, the crossbreeding with the best performance was found in the RC2, while for fishfemale was found in the RC1 (C×CR). Therefore, due to observed differences between fish-female and fish male, we propose a program for obtaining a female line and a male line in order to explore the paternal heterosis on fish-females. Key-words: Gene introgression. Aquiculture. Growth. Breeding program. Heterosis.


Three Gorges Reservoir is an enriched region of the Ethnic Tradition,Nature Endowment and the Regional Culture.Facing the dual development including Modernism and Postmodernism circumstances,the remained historic districts appear some phenomena in a sharp urbanization such as "the Cultural Scrap","the Half-Way Street" and "the Historical Image Arrangement" that is why the renovation is so difficult.After taking a pattern called "Theme Park" as the renovation strategy which is influenced by Tourism industry and Capital Operation,the historic districts can reduce funds pressure of renovation project,protect and continue the regional cultural to make themselves to join the global capital circulation.Commercialization,parody,fragmentation are the main consequence and representation caused by this mode which essentially makes that traditional Spatial-Temporal Structure of historic districts is replaced by artificial Spatial-Temporal Structure.The real motivation of the mode comes from the capital and strides into daily life from the traditional manufacture field,extends the scope from the region to the world,and adjusts the management way from the scale to individualized operation.Finally,it leads the collective production and consumption of Spatial-Temporal Structure.Rebuilding strategy of historic districts is not the criticism of "the theme park" mode,but for setting up the judgments of living value.The application scope of "the theme park" is settled by natural Spatial-Temporal Structure fractures or replacement angle.Regarding the protection and renovation task of traditional daily life,this article utilizes few instance to explain the exploration practical meaning on the historic districts rebuilding which instructed by the "social network" construction.


The supply chain environment is very flexible due to changing demand and pressure from competitors. This article determines that a software architecture is needed to allow information systems to be realigned with the changing supply chain without effort or delay. The characteristics and requirements of the supply chain of the future matches the advantages and characteristics of a software component architecture. The software engineering methodology of component based development, which builds systems using the software structures Components, allows the underlying software architecture to be rapidly changeable. We show how components can be optimized for inter-operability, facilitating the integration of information systems as the supply chain view extends outside of the company. The required specialization of components before they are applicable to supply chain software is explained. Ryan Darby is a supply chain integration and applications consultant with a South African Information Technology service provider focussing on the chemical industry. Ryan's involvement focuses on the identification of emerging technologies and "killer apps" within the extendd enterprise. Ryan is a student of the Department of Computer Science of the University of Pretoria and has an MSc in computer science from the University of Pretoria, completed under supervision of Prof. Bishop of Computer Science, with an application area of supply chain management, under Willem Cilliers of the Graduate School of Management of the University of Pretoria. Ryan's research interests focus on the use of Information Technology to alter the nature of business, particularly supply chain management and the extended enterprise. Judith Bishop is professor of computer science at the University of Pretoria, South Africa. She has a PhD in computer science from the University of Southampton, UK, and has been on academic staff there and at the University of the Witwatersrand. Her research interests include distributed systems, programming languages and web-based programming. She is a founder fellow of the SA Institute of Computer Scientists, and currently chairman of IFIP WG 2.4 (System Programming Languages). Willwm Cilliers holds the position of Chair in Logistics within the Graduate School of Management of the University of Pretoria. Willem has an MBA degree from Pretoria and extensive experience within supply chain strategy consulting. Willem's research interests include benchmarking supply chain performance and supply chain strategy.


In recent years, increasingly strict restrictions on ship emissions and continuously increasing prices of marine fuel oil have made the liquefied natural gas (LNG) using as a marine fuel more attractive, and LNG fueled ships have become more popular in many countries. However, there is still not much research on the development level of LNG fueled ships in different countries, and there are no unified or corresponding evaluation criteria. LNG fueled ships discussed in this study refer to the ships that use the LNG in internal combustion engines, rather than LNG fueled steamships or LNG carriers. On the basis of an appropriate modification of the PEST (Political, Economic, Social and Technological factors) analysis and the idea of the analytic hierarchy process method, a novel SRTI (Strategy, Regulation, Technology and Infrastructure) model is established to evaluate the development level of LNG fueled ships. Taking China, Norway and the United States of America (USA) as an example, a case study on the evaluation of the development of LNG fueled ships is conducted using the evidential reasoning (ER) approach. The results show that Norway performs best according to the proposed model and selected criteria, while China ranks the last. The evaluation results fit the real-world situation to some extent, supporting the applicability of the SRTI model. This work provides a certain reference for further evaluations of the development level of LNG fueled ships in other countries.


[reaction: see text] A straightforward synthetic route for the synthesis of diastereomerically pure psi[(E)-CMe=CH]- and psi[(E)-CMe=CMe]-type dipeptide isosteres was developed on the basis of regio- and stereoselective anti-S(N)2' alkylation of 3-(N-Boc-5-methyl-4-substituted-oxazolidin-2-on-5-yl)acrylates with organocopper reagents.


The aim of the study was to observe the ultrastructure of Cysticercus pisiformis under different state.The Cysticercus pisifomis were obtained in the procedure of slaughter inspection from meat-packing plant.The Cysticercus pisiformis was taken out by cutting cyst directly,or cultured with physiologic saline containing 10% bile until evagination.Then it was observed and recorded by scanning electron microscopy.Observed from top of scolex of Cysticercus pisiformis locate in cyst,the rostellum looked like a umbrella.The cutaneous muscular columns with hamula covered the front end of scolex.Viewed from the side,a row of antlers-liking hamula adhered to the scolex.Four suckers were looked like cavity and distributed around the scolex behind the rostellum.Primary neck segments were more width and body segments less fine,in which there were lots of wrinkles in their surface respectively.The Cysticercus pisiformis cultured was divided obviously into scolex,neck,body segment and zone of cyst.When cutaneous muscular column of rostellum contracted,the antler-liking hamula extended to periphery,and the sucker also had ring-like and vertical shape contraction.It was also found evidently that the ringliking contraction appeared in neck and the lengthways contraction in body segments.The Cysticercus pisiformis under different state has distinctly dissimilar ultrastructure.


It is well established that weather radar systems operating at frequencies approximately equal to 5 GHz or greater can suffer from rain attenuation. Rain rate estimates at these attenuated wavelengths can be accomplished through the Hitschfeld-Bordan (HB) algorithm (Hitschfeld and Bordan, 1954). It has been widely demonstrated that the forward implementation of the HB alghoritm can lead to unstable solutions when the path attenuation becomes large. The divergence associated with the HB method can be prevented by restricting its use for light rain rates. In case of moderate to high rain rates, the attenuation correction is typically based on constrained methods, such as the surface reference techniques (SRT), especially developed for single frequency, incoherent and non-polarimetric airborne weather radars (Iguchi and Meneghini, 1994). These methods uses the path integrated attenuation (PIA) as a constraint in a manner to find a stable solution through a backward implementation of the HB algorithm. PIA measurements are generally extracted from the echo that arise from reference surfaces, such as mountains (for ground-base radars) or the sea (for airborn radars). For polarimetric weather radars, PIA estimate is directly related to ΦDP .


【Objective】 Bovine interleukin-8(IL-8) is one of the major factors recruiting neutrophils during cow mastitis and causing rapid increase of somatic cell counts(SCC).Knowledge of IL-8 polymorphisms would be helpful to genetic selection of low SCC.【Method】 The SNPs in the 5′ upstream of bovine IL-8 gene were investigated in 610 Chinese Holstein cows from 30 bull families in a dairy farm in Shanghai using polymerase chain reaction-single strand conformation polymorphism(PCR-SSCP) technique,and milking traits and somatic cell score(SCS) were measured and their relationship was analyzed using a mixed animal model.【Result】 The results showed that one SNP,A(-180)G,was detected,determining three genotypes,GG,GA and AA with frequencies of 0.41,0.43 and 0.16,respectively.The SNP showed significant effect on SCS,with GG having a significantly lower SCS than GA or AA(P0.01),while this SNP had no effect on test-day milk yield,test-day milk fat content,test-day milk protein content,and 305 d corrected milk yield.【Conclusion】The findings demonstrated that the SNP-180A/G exerted significant effect on SCS.


In photovoltaic cell fabrication, organometals (alkyl metals) may be used in such processes as metalorganic chemical vapor deposition, transparent contact oxide deposition, doping, and ion implantation. Although these compounds offer potential performance advantages over earth metals and possibly greater safety in handling than metal hydrides, they are not without risk to health and property. Most organometals can ignite spontaneously in air. Some also react violently with water. Oxidation by‐products from these reactions are hazardous to health. Of the organometals used in photovoltaic cell fabrication, only the toxicology of organotins (triethyl‐, trimethyl‐ and tetramethyltin) was studied extensively. In mammalian systems, tetramethyltin is rapidly dealkylated to trimethyltin. Although tin was classified by some investigators as an essential trace element, the effects of organotin compounds on humans are poorly known. Animal studies show that the most prominent effects of trimethyltin are on the centra...


The paper presents an overview of various cuts which are used in obtaining the integer solution to an Integer Programming Problem. The decision variables of any problem that must assume non-fractional values may be categorized as an integer programming. The Cut is a device for reducing the feasible region. Whereas the feasible region is a set of feasible solution. Numerous mathematicians and researchers developed various Cuts for different Integer programming problem from time to time. An optimal solution is achieved in a minimum number of phases after using a developed Cut. Integer programming problems are widely used in many applications like Production planning, Scheduling, Telecommunications networks, Cellular network, etc.


Post-COVID-19 patients are at increased risk of cardiovascular and stroke complications, especially the immediate period following infection. Beta-blockers, ACE-inhibitors, anticoagulants and antiplatelet agents are mainstay therapies for stroke patients and those with cardiovascular disease. This study aims to explore the potential benefit of these therapies in post-COVID-19 patients in prevention of cardiovascular and stroke complications. About 5134 cases were analyzed in this study. This study includes patients that were admitted for stroke of myocardial infarction who had history of COVID-19 infection within 4 weeks prior. These patients were then stratified based on their home medications including ACE-I, beta-blockers, antiplatelet and anticoagulant agents. Logistic regression and chi-square were used for analysis of data. There was no significant relationship between statin use and incident of readmission for myocardial infarction. Patients who were on antiplatelet agents were more likely to be readmitted for stroke at 1 and 4 weeks (odds ratio: 2.109 and 2.335, p value: 0.0204 and 0.0036). Patients who were on ACE-I were more likely to be readmitted for stroke at 1 and 4 weeks (odds ratio: 2.0331 and 1.945; p value: 0.0062 and 0.0055). The benefit of statin therapy in COVID-19 patients has been established previously. This is potentially due to two mechanisms: anti-inflammatory properties and lipid lowering. Our studies did not find significant relationship between statin use and incidence of re-admission for myocardial infarction. We deduce that this is due to the anti-inflammatory effect of statins in acute COVID-19, and not the lipid lowering effect. Patients who are on anti-platelet therapy are more likely to be readmitted for stroke. This is likely because they are at high risk for stroke, and COVID-19 increases their systemic inflammatory response and therefore increase stroke risk. Lastly, our study suggests there may be some relationship between ACE-I use and stroke post-COVID-19 infection.


This paper, the second in a series on radiation-regulated accretion onto black holes (BHs) from galactic scales, focuses on the effects of radiation pressure and angular momentum of the accreting gas. We simulate accretion onto intermediate-mass black holes, but we derive general scaling relationships that are solutions of the Bondi problem with radiation feedback valid for any mass of the BH Mbh. Thermal pressure of the ionized sphere around the BH regulates the accretion rate, producing periodic and short-lived luminosity bursts. We find that for ambient gas densities exceeding ncrH, ∞∝M−1bh, the period of the oscillations decreases rapidly and the duty cycle increases from 6%, in agreement with observations of the fraction of active galactic nuclei at z ∼ 3, to 50%. The mean accretion rate becomes Eddington limited for nH, ∞ > nEddH, ∞ ≃ ncrH, ∞T∞, 4−1 where T∞, 4 is the gas temperature in units of 104 K. In the sub-Eddington regime, the mean accretion rate onto BHs is about 1%T2.5∞, 4 of the Bondi rate, and thus is proportional to the thermal pressure of the ambient medium. The period of the oscillations coincides with the depletion timescale of the gas inside the ionized bubble surrounding the BH. Gas depletion is dominated by a pressure gradient pushing the gas outward if nH, ∞ < ncrH, ∞ and by accretion onto the BH otherwise. Generally, for nH, ∞ < ncrH, ∞ angular momentum does not significantly affect the accretion rate and period of the oscillations.


AIM:To observe the therapeutic efficacy of Huoxiangzhengqi Oral Liquid (Herba Agastaches seu Pogostemi, Radix Angelicae Dahuricae, Rhizoma Atractylodis, Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Pericarpium Arecae) and Tablet of Radix et Caulis Acanthopanacis Senticosi on the withdrawal symptoms from heroin. METHODS: 143 cases were randomly divided into three groups, namely control group (n=44), treating group A (n=48) and B (n=51). They were detoxified by using Lofexidine Hydrochloride Tablet (LFX) for 12d, and then, the control group took an imitate preparation, the treating group A took Huoxiangzhengqi Oral Liquid and Tablet of Radix et Caulis Acanthopanacis Senticosi for 60d, But group B took Huoxiangzhengqi Oral Liquid and Tablet of Radix et Caulis Acanthopanacis Senticosi from the time when detoxification began. And then, 10d after the two treating groups stopped taking Huoxiangzhengqi Oral Liquid and Tablet of Radix et Caulis Acanthopanacis Senticosi, the protracted abstinent syndromes of the three group were observed and scored for 7d. One year later, the drug re abusing case of the three groups were investigated through urinoscopy. RESULTS: The scores of the protracted abstinent symptoms of the three groups were distinctively different. The scores of the treating group were lower than those of the treating group A ( P 0.01), and the scores of treating group A were lower than those of the control group ( P 0.05). CONCLUSIONS: Huoxiangzhengqi Oral Liquid and Tablet of Radix et Caulis Acanthopanacis Senticosi relieve effectively the withdrawal symptoms in eary time and the protrated abstineat symptoms and reduce the re abuse drugs rate after detoxification.


Hidden nodes in a wireless network refer to nodes that are out of range of other nodes or a collection of nodes. We will discuss a few problems introduced by the RTS/CTS mechanism of collision avoidance and focus on the virtual jamming problem, which allows a malicious node to effectively jam a large fragment of a wireless network at minimum expense of power. We have also discussed WiCCP (Wireless Central Coordinated Protocol) which is a protocol booster that also provides good solution to hidden nodes.


Salacca dransfieldiana Mogea,S. magnifica Mogea and S. sarawak ensis Mogea are proposed as new species of flabellate-leaved Salacca.A key to the four recognized species, descriptions and illustrations are presented.


Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) have been used to study grain morphology and grain boundaries in superconducting Bi/sub 2/Sr/sub 2/CaCu/sub 2/O/sub x/ fibers produced by gas-jet fiberization. The narrowest fibers are composed of chains of platelets of about 52*3*0.2 mu m/sup 3/ oriented such that the long direction in each platelet is primarily parallel to the fiber axis. Each platelet has one crystallographic orientation. with the c-axis corresponding to the thin direction. These crystallites commonly join via large-angle


[21946-42-9] C38H30N2NiP2 (MW 635.31)

InChI = 1S/2C18H15P.2CN.Ni/c2*1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18;2*1-2;/h2*1-15H;;;

InChIKey = KBSXFMJOIORMAN-UHFFFAOYSA-N

(nickel(II) complex useful for the oligomerization of norbornadiene2 and the isomerization of alkenes3)

Physical Data: mp 212 °C (dec).

Solubility: only sparingly sol most organic solvents; most sol CH2Cl2.

Preparative Method: dry nickel(II) cyanide (11 g) was refluxed in 1 L ethanol with 78 g Triphenylphosphine for 48 h. The yellowish-gray Ni(CN)2 turned to a light yellow coarse crystalline mass. The solvent was decanted and the solid was rinsed with ethanol to remove unreacted PPh3. The remaining solid product was dried, extracted with CH2Cl2, and filtered to exclude insoluble Ni(CN)2. Removal of solvent provided 39 g (62%) of light yellow crystals.4

Handling, Storage, and Precautions: air stable. Store at rt.


2 Anderson CS, Jamrozik KD, Burvill PW, Chakera TMH, Johnson GA, Stewart-Wynne EG. Determining the incidence of different subtypes of stroke: results of the Perth Community Stroke Study 1989-1991. Med3JAust 1993; 158:85-9. 3 Mohr JP, Nicholas FT, Tatemichi TK. Classification and diagnosis of stroke. Int Angiol 1984;3:431-9. 4 Bamford J, Sandercock P, Dennis M, Burn J, Warlow C. Classification and natural history of clinically identifiable subtypes of cerebral infarction. Lancet 1991 ;337: 1521-6. 5 Anderson CS, Jamrozik KD, Burvill PW, Chakera TMH, Johnson GA, Stewart-Wynne EG. Ascertaining the true incidence of stroke: experience from the Perth Community Stroke Study 1989-1991. MedJAust 1993; 158:80-4. 6 WHO MONICA Project principal investigators. The World Health Organisation MONICA Project (monitoring trends and determinants in cardiovascular disease)a major international collaboration (prepared by H Tunstall-Pedoe). JT Clin Epidemiol 1988;41: 105-14. 7 Teasdale G, Murray G, Parker L, Jennet B. Adding up the Glasgow coma scale. Acta Neurochir (Wein) 1979; 28(suppl): 13-6. 8 Demeurisse G, Demol 0, Robaye E. Motor evaluation in vascular hemiplegia. Eur Neurol 1980;19:382-9. 9 Bamford J, Sandercock P, Warlow C, Slattery P. Interobserver agreement for the assessment of handicap in stroke patients. Stroke 1989;20:828. 10 Sandercock P, Allen C, Corston R, Harrison M, Warlow C. Clinical diagnosis of intracranial haemorrhage using Guy's Hospital score. BM3r 1985;291:1675-8. 11 Gardner MJ, Altman DG. Confidence intervals rather than P values: estimation rather than hypothesis testing. BM3r 1986;292:746-50. 12 SPSSfor Windows V5.0.1. Chicago, Ill: SPSS Inc. 1992. 13 EGRET statistical package. Seattle: Statistics and Epidemiology Research Corporation, Seattle. Washington, 1991. 14 Lindley RI, Warlow CP, Wardlaw JM, Dennis MS, Slattery J, Sandercock PAG. Interobserver reliability of a clinical classification of acute cerebral infarction. Stroke 1993;24: 1801-4. 15 Bogousslavsky J, Caplan LR. Vertebrobasilar occlusive disease: review of selected aspects. Cerebrovascular Diseases 1993;3: 193-205. 16 Sandercock P, Molyneux A, Warlow C. Value of computed tomography on patients with stroke: Oxfordshire Community Stroke Project. BMJ 1985;290: 193-7. 17 Ebrahim S. Clinical Epidemiology ofStroke. Oxford: Oxford Medical Publications, Oxford University Press, 1990: 147-97. 18 C6te R, Battista RN, Wolfson C, Boucher J, Adam J. The Canadian Neurological Scale: validation and reliability assessment. Neurology 1989;39:638-43. 19 Brott T, Adams HP Jr, Olinger CP, et al. Measurements of acute cerebral infarction: a clinical examination scale. Stroke 1989;20:864-70. 20 Barer DH, Mitchell JRA. Predicting the outcome of acute stroke: do multivariate models help? Q J Med 1989;70: 27-39. 21 Gladman JRF, Harwood DMJ, Barer DH. Predicting the outcome of acute stroke: prospective evaluation of five multivariate models and comparison with simple methods. J Neurol Neurosurg Psychiatry 1 992;55: 347-51. 22 Lyden PD, Lan GT. A critical appraisal of stroke evaluation and rating scales. Stroke 1991;22:1345-52.


Organizing their review around a scene from the 1939 movie "The Wizard of Oz," Shaner et al. offer a model procedure for communicating the diagnosis of death by neurologic criteria. An unequivocal, straightforward approach provides a message better understood by family and staff. Confusion and inconsistent decision-making is reduced with adherence to policy.

see page 1683

Saper et al. studied treatment response, compliance, and other variables in 160 patients placed on daily opioid therapy for intractable head pain. They found that only a quarter of the patients showed sustained improvement over 3 to 5 years; many of these failed to improve in functional activity or non-opioid medication reduction. Medication noncompliance/misuse was identified in up to 50% of patients, despite intense supervision of treatment.

see page 1687

Narcotics are not considered first line therapy for migraine …


The effect of Sn addition to Pt/CeO2-Al2O3 and Pt/Al2O3 catalysts was studied with X-ray photoelectron spectroscopy (XPS), Sn Mössbauer spectroscopy and adsorption microcalorimetry of CO at room temperature. Catalysts were reduced in situ at 473 ("non-SMSI state") and 773 K ("SMSI state"). Sn Mössbauer and XPS results indicated that the presence of cerium in bimetallic catalysts inhibited reduction of tin. Furthermore, it was found that tin facilitated reduction of cerium (IV) to cerium (III). Microcalorimetric analysis indicated that cerium addition caused the appearance of a more heterogeneous distribution of active sites, whereas tin addition led to a higher homogeneity of these sites. Reduction at 773 K decreased the Pt surface area as measured by CO chemisorption for all catalysts used in this study. Tin addition to Pt/Al2O3 and Pt/CeO2-Al2O3 also decreased the Pt surface area due to formation of PtSn and possibly Pt-SnOx species. Cerium addition to Pt/Al2O3 caused a loss of Pt surface area only when the catalyst was reduced at 773 K, presumably due to migration of the reduced cerium onto Pt particles. Cerium addition to Pt/Al2O3 caused an increase in the catalytic activity for crotonaldehyde hydrogenation, whereas Sn addition to Pt/Al2O3 decreased the activity of Pt/Al2O3 catalysts. Higher reduction temperature caused an increase in the initial catalytic activity for crotonaldehyde hydrogenation for all the catalysts studied. Selectivity enhancements for crotyl alcohol formation in


Background and Objective: Cancer survival has improved significantly, which reflects the achievements in screening, diagnosis, and treatment. As a consequence, multiple primary malignancies are diagnosed more frequently, with an incidence ranging from 0.52–11.7%. The types of malignancy that coexist and survival patterns vary notably in different countries and geographical areas. Due to the limited literature in Saudi Arabia, a baseline of prevalent malignancy combinations and their survival patterns would support early detection and disease management. Method: This was a retrospective descriptive study conducted from 1993–2022 at King Abdulaziz Medical City, Department of Medical Oncology, Riyadh, Saudi Arabia. Patients with at least two biopsy-proven solid malignancies were included. Patients with hematological malignancies, missing data, or an uncertain or indecisive pathology report were excluded. Result: In total, 321 patients were analyzed. More than half (57.3%) of the patients were female. A third (33%) of the cases were synchronous, and 67% were metachronous. The most frequent site of the first primary malignancy was breast cancer, followed by colorectal, skin, and thyroid cancers. The most frequent site of the second primary malignancy was colorectal cancer, followed by thyroid, breast, and liver cancers. Only 4% of the cases had a third primary malignancy, with colorectal and appendiceal cancers being the most frequent. The most frequently observed histopathology in the synchronous and metachronous malignancies was adenocarcinoma. Breast–colorectal, breast–thyroid, and kidney–colorectal were the most frequently observed malignancy combinations. Conclusion: The current study offers a baseline of multiple primary malignancies in Saudi Arabia and provides supporting evidence that the pattern of multiple primary malignancies varies among different countries and ethnicities. The possibility of developing another primary malignancy should be considered when treating and monitoring cancer patients.


The spherical CaCO3 composite was synthesized in the presence of the amphiphilic block copolymer, i.e. polystyrene-b-poly(acrylic acid). It was revealed by XRD analysis that the grains in the composite was calcite with great distortion. Infared and Raman analysis showed that the composite was composed of PS-b-PAA calcium salt and calcite, and the calcite was nano-scaled.


Thank you very much for downloading separating parents and adolescents a perspective on running away schizophrenia and waywardness. Maybe you have knowledge that, people have look hundreds times for their favorite novels like this separating parents and adolescents a perspective on running away schizophrenia and waywardness, but end up in malicious downloads. Rather than enjoying a good book with a cup of tea in the afternoon, instead they are facing with some harmful virus inside their desktop computer.


Abstract The forthcoming restoration campaign of the former house of the Flemish Baroque painter Pieter Paul Rubens (1577–1640) in Antwerp includes the design and construction of a new glass canopy. It is to replace the actual non-transparent roof structure, which was erected in the 1990s to protect the portico, separating the inner court yard of the house from the gardens, and especially its sculptural artworks from further material loss. The design parameters of the new glass canopy were evaluated based on the distribution probability of the rain on the portico as a function of rain intensity and wind velocity, while the rain distribution was determined based on the raindrop trajectories combining the vertical raindrop velocity and the horizontal drag from the wind. A minimum wind velocity of 40 km/h is required before rain can reach the feet of the sculptured artworks during intense rain showers. Statistical analysis of the hourly wind velocity and rain shower duration and intensity reveals a return period of approximately 4.2 years when the portico is protected by a glass canopy with identical dimensions of the actual provisory roof structure. Although the influence of intermittent wind gusts and squalls, which will more frequently drag along rainwater to the critical areas, and increase the amount of rainwater attaining the artworks during storms, could so far not be studied more in detail. The above risks are however considered acceptable to prevent future damage accumulation.


Introduction: Kahibah Creek at Umina Beach is a complex creek system with many meandering tributaries and shallow lagoons. It also has a very flat longitudinal gradient. The creek has expanses of both native and weed vegetation and this vegetation, if not controlled, can elevate flood levels to the adjoining urban development to dangerous levels. Much of the system has been altered in the past by drainage works; however an ecological management plan for the creek requires that it be maintained in an ecologically sustainable manner.


The present invention relates to a carbon dioxide stripping urea stimulation energy-saving technology and its equipment, including increased absorption of the medium pressure decomposition heat recovery and vacuum technology, increase the medium pressure decomposition absorption system changed into three two evaporation evaporated medium-pressure stripping decomposition of the upper turret arranged rectifying section, a heating section of the lower portion, the lower liquid synthesis column and the stripper solution were confluent, the medium pressure decomposition into the stripper, the urea carbamate solution in contact with the rectifying section decomposed gas countercurrent depressurization, after rectifying the tube into the heating section, to promote decomposition of carbamate and ammonia, carbon dioxide, from the shell side 185 ~ 195? C of steam heating, and then into the medium-pressure carbamate condenser for condensing, the bottom urea solution into the urea carbamate distillation tower further decomposition; through this program, to overcome the bottleneck increase carbon dioxide stripping urea, urea production capacity has increased substantially, the corresponding decline in energy consumption indicators, the better solution because of the ammonia nitrogen fertilizer business expansion contradictory urea production capacity of urea production capacity increased by 50%.


Named in honor of Canada's first professional palaeontologist, Lawrence Lambe, Lambeosaurus was among the largest of the hadrosaurs, or duckbilled dinosaurs.


Summary Geological structure and composition of the Maikop series as well as geochemical and petrophysical properties of the Maikop series clay rocks of the southern margin of the East European Platform are considered. The sections of the Maikop series of Black Sea and the Crimean region, including the north-western area of the Black Sea shelf (wells Arkhangelsk-21, Golitsyn-1, 6, 7, 9, 12, 28); the central part of the Crimean peninsula (Dzhankojsk-1); the Kerch Peninsula (Fontanovsk-6, 12); the Azov Sea shelf (Nord-Kazantip-3); Near-Kerch area of the Black Sea shelf (Subbotin-1) are described. Comparative analysis is made between the Maikop series depositions that occur in following regions – the Kerch-Taman trough, the eastern part of the Black Sea, the Indol-Kuban Trough, West, Central and East Caucasus, the Middle Caspian, West Azerbaijan, South-Caspian depression.


A PIV system is developed that enables in vivo PIV measurements in small blood vessels with periodically moving boundaries such as the heart of a chicken embryo. Fluorescent lipid micro-spheres serve as tracer particles. The velocity distribution within the ventricle and the atrium of an embryonal chicken heart can be resolved.


e18647 Background: Patients with comorbidities especially those with oncological diseases could have severe COVID-19 outcomes. OBJECTIVE: The aim of this study was to evaluate the role of prolonged positivity of SARS-Cov2 in evolution of patients with various neoplasia. Methods: We analysed clinical and laboratory (hematological parameters and inflammatory markers: interleukin-6 and ferritin) data of COVID-19 patients admitted in intensive care unit (ICU) Department of our hospital, during 2020-2021 and presented in medical history solid tumors or haematological neoplasia . The cohort of patients included 78 patients with severe and critical form of COVID-19, 31 patients with solid tumors and 47 patients with hematologic malignancies. We consider long COVID-19 all cases with SARS Cov2 positivity more than 14 days. Results: The frequency of long COVID-19 was quite equal between patients groups with solid tumors and hematologic malignancies, incidence rate 1:2, the incidence rate differences was 1:18, p = 0.75. Long COVID-19 was observed in 60% cases with favourable evolution, Chi-squared 5.35%, p = 0.02, these patients had moderate form and was admitted in hospital in 1 or more days after the onset, median value 3 (min 1, max 55) compared with patients with normal duration of positivity of SARS-Cov2 test- median value 2 (min 1, max 8), p = 0.01. The Kaplan Meyer survival analyses indicated long COVID-19 as predictive factor for unfavourable evolution, Chi-squared 17.97, p < 0.0001. Although we have not obtain significant differences, we observed more severe lymphopenia in patient without long COVID-19, probably because a part of these patients group died in the first 14 days of COVID-19 (0.765 (min 0.04, max 297.64) vs. 1.01 (min 0.09, max 254.35), p = 0.09). The rest of hematological and biochemistry parameters was not significant different between groups. Infectious and thrombotic complication was most frequent in patients with long COVID-19, Chi squared 8.6, p = 0.003. Conclusions: Long Covid-19 is predictable for unfavourable evolution and is associated with sepsis and thrombotic complication. This diagnosis is frequent in patients who was admitted in hospital after the onset of COVID-19 symptoms, early treatment of COVID-19 in oncological patients being very important for favourable evolution.


The aim of this study was to compare the efficacy and safety of intravenous JR‐131, a darbepoetin alfa biosimilar, to darbepoetin alfa in hemodialysis patients with renal anemia. In this 24‐week, multicenter, randomized, double‐blinded, parallel‐group phase 3 study, 334 hemodialysis patients with renal anemia who had been receiving darbepoetin alfa were randomized to either JR‐131 or darbepoetin alfa group. The initial dose was set based on the darbepoetin alfa dose during the observation period. The primary endpoint was change in hemoglobin level from baseline to end of treatment. The 95% confidence interval of the difference in the change in hemoglobin level between the groups was −0.19 to −0.20 g/dL, within the equivalent margin of −0.5 to 0.5 g/dL. No notable treatment‐emergent adverse events were observed in either group. JR‐131 was therapeutically equivalent to darbepoetin alfa, and the safety profile of JR‐131 was similar to that of darbepoetin alfa.


I. INTRODUCTION TO USENET. 1. Meet the USENET Community. 2. People Using USENET. 3. An Overview of USENET. 4. Basic Terms and Conventions. 5. Close Examination of a Newsgroup. II. THE NEWSGROUPS OF USENET. 6. About This Part of the Book. 7. Computers: The "comp" Newsgroups. 8. Miscellaneous: The "misc" Newsgroups. 9. News: The "news" Newsgroups. 10. Recreation: The "rec" Newsgroups. 11. Science: The "sci" Newsgroups. 12. Society: The "soc" Newsgroups. 13. Talk: The "talk" Newsgroups. 14. Worthy Mentions from the Alternative Set. 15. Other Available Hierarchies. III. ACCESSING USENET. 16. Boning Up on the Basics. 17. Gaining USENET Access. 18. Topics for Further Exploration. APPENDICES. A. Articles from the Source. B. List of the Alternative Hierarchy. C. A Word About News Readers. D. Recommended Reading. Glossary. Index.


The article analyzes the work carried out in the USSR on child labor protection in the early 1920's on the example of Omsk. The connection of the studied issue with the historiography of the problem is given. In the context of the legislative framework affecting the work of adolescents and the work of supervisory authorities, the problems faced by minors when applying for work are studied, the difficulties of the situation of children in Omsk are outlined, where one of the solutions to improve their situation was assistance in finding employment. The work of Omsk labor protection inspectors is studied using specific examples. The publication is addressed to researchers of everyday life, the history of labor relations and childhood in Western Siberia in the early 1920's.