Apple and Starbucks are two of the world's most trusted companies, but their reputations were recently tarnished thanks to some novice cybersecurity mistakes. Both setup systems that could have allowed hackers to break into customers' accounts by repeatedly trying different passwords, a procedure commonly known as a "brute force" attack. The mistake both firms made was in not employing the simple tactic of automatically locking accounts after several failed attempts to enter a password. Last week it was revealed such tactics allowed thieves to steal money from users of Starbucks' mobile app. In 2014, an investigation around the publishing of nude photos of celebrities taken from their iCloud storage accounts, identified that intruders could access Apple's Find My iPhone app by continually trying different login details. In order to protect against this type of attack, many sites block login after a given number of incorrect attempts. The system can then go into a permanent lock-out mode (where the user must perform a lock-out procedure, such as calling the hosting company to verify their account), or lock out for a given time (known as the hold-down time).


Recently, electric vehicles (EVs) have proven remarkable impacts on reducing pollution and their suitability for utilizing renewable energy sources (RESs) instead of fossil fuels. The continuously increasing number of installed EVs has encouraged their employment for performing additional functionalities in utility grids. This paper provides study for the impacts of EV integration approaches on enhancing the operation of utility grids. The proposed study considers the targeted renewable energy powered utility grids with installed energy storage devices. Wind energy has been utilized as a case study for the RES with considering its stochastic characteristics and its continuous fluctuations with wind speed. Additionally, the superconducting magnetic energy storage system (SMES) device is chosen due to its promising long-life operation. The various aspects of point of common coupling (PCC) voltage fluctuations, reactive power support, leveling active power of the on-peak period, and power losses are considered in the proposed study. Moreover, fuzzy logic controller (FLC) systems have been proposed for controlling EVs and the SMES device. The energy management between the installed EVs, SMES, wind, and utility grid side is achieved through the coordination of the FLC systems. The results show that reduced peak and mean values of total power losses and line active power are obtained by the proposed coordination method. Moreover, improved profiles of the PCC voltage, reactive power support, active power leveling, and sustainable and reliable power supply are obtained by the proposed method for wide operating ranges and modes of operation.


Some α,β-unsaturated ketones 4a–g of 3-acetyl-4-hydroxyquinolin-2(1H)-one were prepared and converted into a series of new hybrid compounds, quinoline-benzothiazepine 6a–g. Compounds 6d and 6g had the best activity against HepG2 and KB cell lines.


During a field study in Bazian Plain which is one of the most important agricultural areas in Sulaymaniyah it became clear that current scenario is linked to rapid climate change directly. Arid and semi-arid ecosystems are likely to be particularly affected by changes in wind speed and vapour pressure regimes, changes in those regimes may show from climate data that vapour pressure has clearly increased during these years. For instance, in January and February of 2017 wind speed reached 8 and 9 (m. sec.-1). Sulaymaniyah Meteorology Department reported a lesser speed of 0.1 (m. sec.-1) in the months 4, 5, 6 and 9, on average the greatest rates of 3.1 and 2.2 (m. sec.-1) in 1985 and 1992. on the other hand, in 1991 recorded the lowest rate of (1 m. sec.-1) amounts and times of precipitation during the study years, floods occurred in some seasons the dry seasons less than 300 (ml) were very few, while the remaining seasons were more than 450 (ml) rainfall amounts in the seasons 2006-2007, 2007-2008 and 2008-2009 were among the driest seasons during the years of the study Which was straight (66000, 87000, 86000) dunam. as the agricultural areas were reduced to their lowest levels, although the levels of precipitation were acceptable. The data gathered found that the average annual temperature rate has increased by over 1.3(°C) with the warmest year for this time being recorded in 2010 at 21.55(°C). Sunshine was the lowest in terms of the number of daylight hours in December with total annual averages for the period 1985-2022 for December being 184.4 (hours) 1996 was the lowest with 2.3 (hr.) and 2018 was also the second lowest with a value of 3.3 (hr.) During the decades of the study period, wheat growing seasons advanced mostly to November, and in recent decades (2011-2020) (2010-2009) 20 farmers plant in December to ensure rainfall.


expression profiling of tumour epithelial and stromal compartments during breast cancer progression. expression profiling of tumour epithelial and stromal compartments during breast cancer progression. Abstract Introduction: The progression of Ductal Carcinoma in situ (DCIS) to Invasive Ductal


The utility model relates to a construction engineering device, which mainly is composed of an upper platform, a girder, a moulding board, a middle platform, a lower platform, a rail, a buried piece supporting base and a hydraulic system. By using the crawling theory like a caterpillar, the moulding board and the rail are moved up in turn as an integrated whole, thereby realizing the purpose of concrete pouring. The utility model eliminates the old stand method of pouring concrete, saves plenty of manpower, materials and time with a high safety factor; the concrete wall is plane and clean without the need of a second time plastering. No matter how high the moulding floor is, the hydraulic crawling mould can be assembled at one time without the assembly and disassembly of the moulding board during the process of construction until the end of the work.


The success of data mixing augmentations in image classification tasks has been well-received. However, these techniques cannot be readily applied to object detection due to challenges such as spatial misalignment, foreground/background distinction, and plurality of instances. To tackle these issues, we first introduce a novel conceptual framework called Supervision Interpolation, which offers a fresh perspective on interpolation-based augmentations by relaxing and generalizing Mixup. Building on this framework, we propose LossMix, a simple yet versatile and effective regularization that enhances the performance and robustness of object detectors and more. Our key insight is that we can effectively regularize the training on mixed data by interpolating their loss errors instead of ground truth labels. Empirical results on the PASCAL VOC and MS COCO datasets demonstrate that LossMix consistently outperforms currently popular mixing strategies. Furthermore, we design a two-stage domain mixing method that leverages LossMix to surpass Adaptive Teacher (CVPR 2022) and set a new state of the art for unsupervised domain adaptation.


Summary form only given. The method of auxiliary sources (MAS) has been extensively used for solving the different type of applied EM problems. The key idea of the MAS is to represent the unknown scattered field by a sum of fundamental solutions of appropriate wave equation-auxiliary sources (AS), whose radiating centers are located on some auxiliary surface shifted outside the area where the unknown field is sought. The following applied EMC and other problems were solved by the MAS using different type of AS and are presented: (1) diffraction on a spherical body with an aperture, using the elemental dipoles for the AS; (2) diffraction on an open metal cube with non-symmetrical excitation using the piecewise-sinusoidal distribution of auxiliary current on the auxiliary surface which is modeled with a grid; and (3) modeling of a portable resonant antenna with dielectric substrate and metal back reflector using the piecewise-linear distribution of the auxiliary current. In all these problems the best choice of AS and the advantage of each type used is discussed.


A patient with LEMS unrelated to cancer was studied by stimulated single‐fiber electromyography (SFEMG) before and 3 months after the onset of therapy with 3,4‐diaminopyridine. All end‐plates showed a progressive reduction in blockings and jitter with the increase in stimulation rate. Treatment significantly corrected this feature, but the overall pattern of frequency‐improved jitter remained. Such widespread finding is rare but diagnostic for Lambert‐Eaton myasthenic syndrome. Stimulated SFEMG can be used to monitor therapy in such patients. © 1997 John Wiley & Sons, Inc. Muscle Nerve, 20, 735–739, 1997.


This report describes experimental and analytical efforts to evaluate fracture of stainless steel flux-welded pipe. Seven pipe fracture experiments (four with through-wall circumferential cracks and three with circumferential internal surface cracks) were conducted at 550/sup 0/F (288/sup 0/C). Material characterization efforts involved laboratory specimen tests to assess specimen size effects, effects of solution-annealing, and crack-growth behavior in the HAZ, along the fusion line, and in the weld metal. Efforts involved assessing the net-section-collapse analysis, the plastic-zone screening criterion, inherent safety margins in the IWB-3640 flux weld analysis, through-wall-cracked pipe predictive J-estimation schemes for LBB analyses, eta-factor J-R curves calculated from the pipe experiments for comparison to C(T) specimen results, and finite element analysis of C(T) specimens and one pipe experiment. This report also evaluates the technical significance of these results and their significance relative to licensing decisions.


Baltic sprat (Sprattus sprattus balticus) and Baltic herring (Clupea harengus membras L) are two of the most caught fish species among the Estonian seacoast fishermen, and therefore it is important to understand catching season effects on sprat and herring sensory and nutritional quality. The aim of this study was to measure and compare sensory and chemical variability of Baltic sprat and Baltic herring during different catching seasons. Batches of Baltic sprat and Baltic herring were caught from different locations in Estonian coastal waters from February 2008 until April 2009. Water content, protein content, lipid and ash content were measured. Descriptive sensory evaluation of steamed fish was conducted and results analyzed using Partial Least Squares Regression. The results suggested differentiation possibilities between fish from different seasons. The variations lie in fat and water contents, hardness, characteristic flavor and sweetness of the fish flesh.


Observational associations between high body mass index (BMI) and putatively improved outcomes after percutaneous coronary intervention (PCI) have been called the "obesity paradox." The present study shows no association between two year PCI outcomes and BMI ranging from 23 to 34 kg/m. Under-represented in this study, the BMI extremes of <23 and >40 kg/m are associated with worse outcomes in the broader literature; but require further study including lean body mass index.


Let B be a complex unital Banach algebra. We consider the Banach algebra A = B x C ordered by the algebra cone K = {(a,ξ) ∈ A: ||a|| ≤ ξ}, and investigate the connection between results on ordered Banach algebras and the right bound of the numerical range of elements in B.


An investigation into perverting influence in catogory assessment scales, with particular reference to precision in the objective assessment of attitude. Also a comparison between category scaling and an application of paired comparisons.

The writers approach to precision in attitude scaling is derived from an exposition of propaganda, defined in terms of attitude manipulation. The attitude-action discrepancy is discussed in relation to cultural stereotypes and stereotypical behaviour. Category scaling procedures are critically described and discussed, together with paired comparisons, Cutman scalogram analysis, and questionnaire methodology. Experiments are carried out to amplify and clarify the perverting influences on category scaling as discussed. Also experiments are carried out to provide data on the relative precision in item selection, and ease of application of category scaling methodologies and an application of paired comparisons. Multiple partial ranking, an adaptation of paired comparisons, is discussed in relation to attitude scaling methodologies.


A software program has been designed that successfully runs a stereophonic acoustic echo canceler natively on a personal computer. This is a major achievement since an echo canceler requires that the soundcard's input and output signals are time-synchronous. Synchronizing the audio streams is a great challenge in such an "asynchronous" environment as the operating system of a PC. Furthermore, stereophonic echo cancellation is significantly more complicated to handle than the monophonic case because of computational complexity, nonuniqueness, and convergence problems. Special care has to be taken in the algorithm design. This work presents the core algorithms, i.e., the adaptive algorithm and the double-talk detection algorithm of the implemented echo canceler.


Objective To correlate ultrasound characteristics of spastic muscles with clinical and functional measurements in chronic stroke survivors. Methods Ultrasound assessment and clinical and functional assessments were performed in 28 ambulatory stroke survivors (12 females, mean age 57.8 ± 11.8 years, 76 ± 45 months after stroke). Results Muscle thickness in the affected side was decreased compared with the contralateral side (p < 0.001). The decrease was more evident in the upper limb muscles. On the affected side, the modified Heckmatt scale score was lowest (closer to normal) in the rectus femoris (RF) muscle compared with other muscles (biceps brachii (BB), flexor carpi ulnaris (FCU) and medial gastrocnemius (MG)). Muscle thickness and echogenicity of spastic muscles did not correlate with spasticity, as measured with the modified Ashworth scale (MAS), Fugl-Meyer motor assessment scores, age, or time since stroke. There was a significant negative correlation between grip strength and percentage decrease in muscle thickness for the spastic FCU muscle (r = –0.49, p = 0.008). RF muscle thickness correlated with ambulatory function (Timed Up and Go test (r = 0.44, p = 0.021) and 6-metre walk test (r = 0.41, p = 0.032)). There was no significant correlation between echogenicity and functional assessments Conclusion Ambulatory chronic stroke survivors had function-dependent changes in muscle thickness on the affected side. Muscle thickness and echogenicity of spastic muscles did not correlate with spasticity, Fugl-Meyer motor assessment scores, age, or time since stroke. LAY ABSTRACT Muscle changes occur secondary to various factors after stroke. In this study, ultrasound characteristics of spastic muscles and clinical and functional assessment were performed in 28 ambulatory chronic stroke survivors. Muscle thickness in the affected side was decreased compared with the contralateral side. The decrease was more evident in the upper limb muscles. The percentage decrease in the flexor carpi ulnaris muscle thickness correlated negatively with grip strength, while the rectus femoris muscle thickness correlated with ambulatory function. Echogenicity was lowest in the rectus femoris compared with other muscles. Muscle thickness and echogenicity of spastic muscles did not correlate with spasticity, Fugl-Meyer motor assessment scores, age, or time since stroke. These function-dependent changes in muscles on the affected side suggest an important role of voluntary muscle activation in preserving muscle mass after stroke. Stroke motor rehabilitation programmes should focus on active use of muscles on the affected side for strengthening and preserving muscle mass.


This paper shows the results of a research which aimed at describing the conceptions of professors concerning teaching and assessment of academic writing. Ten professors of Psychology, five working in a French university and five working in a Colombian one, were interviewed on two subjects: what are the recommendations they communicate to their students when these have to write their written tasks?, and ?what are the criteria used to assess the academic texts produced by their students? It was found that the participants declared to be involved in teaching and assessing of academic writing, mainly through a discursive perspective which aims particularly at teaching some specific norms of academic genres in Psychology. Also, some discrepancies between assessing and teaching practices are revealed, mainly concerning epistemic function of writing and the linguistic dimension; also, a few differences between the samples are found concerning methods to teaching.


In this paper the author contrasts 'green businesses' with 'green-green businesses'. The ideal type of 'ecopreneur' is defined as one who creates green-green businesses in order to radically transform the economic sector in which he or she operates. Similarly, ecopreneurship is seen as an existential form of business behaviour committed to sustainability. Some 'ideal-type' illustrations of ecopreneurship are given, including recent examples, having in common an accidental evolution into ecopreneurship that then becomes transformative for self, society and economic sector. The author provides some practical suggestions for businesspeople who want to try an ecopreneurial strategy in the private sector, including: green brainstorming; cost reduction; the stimulation of innovation through green design and networking; and the attraction of interest of overwhelmed consumers in an emerging 'attention economy' through green marketing and through green start-ups ('green-green businesses'). He suggests that, to promote ecopreneurship, governments and public officials can: run competitions for the most imaginative green business plans; change tax regimes to promote resource conservation; build ecopreneurship into standards for public-sector managers to meet; and target the creation of high-technology development centres to build serial ecopreneurship and to attract 'blended value' venture capital. (Publication abstract)


SKI-combinator trees are a simple model of computation, which are computationally complete (in a Turing sense), but are suggestive of basic biochemical processes and can be used as a vehicle for understanding processes of biological (and prebiotic) self-organization. After a brief overview of SKI-combinator trees, we describe the results of a series of preliminary experiments exploring the statistical properties of populations of random SKI-combinator trees. We show that in such populations a signiicant fraction of the trees will exhibit complex, non-terminating growth patterns, suggestive of biological processes. Further, we show that the fraction of S-combinators in such trees is an important parameter deening a sharp phase transition between (uninteresting) terminating behavior and (interesting) nonterminating growth. (This is related to the \edge of chaos" investigated by Chris Langton.) Finally, we discuss some of the follow-on investigations suggested by these exploratory experiments. support is gratefully acknowledged. This report is in the public domain and may be used for any non-proot purpose provided that the source is credited.


plot summaries of very well known narratives and predictable and honorific readings of them: Carrier's "Paul's Case" provides "insight into the homosexual's plight in American society" at the turn of the century (p. 62); "the animating theme of the early fiction of Capote and Williams," we are told, " is the universal human need for love" (p. 130). The earnest Christian-humanist tone of the book becomes fully explicit in the closing discussion of Isherwood (!), where an image in his novel A Single Man is said to "symbolizfe] the unity within diversity of mankind and the universality of God's offer of grace," and Summers refers the reader to the second chapter of Acts (p. 210). Robert F. Kiernan's Frivolity Unbound reproduces a second largely outmoded model from early gay literary studies, that of "the camp sensibility." In contrast with the frequently dire situations in the fictions Summers discusses, life, especially "queer" life in its various forms, appears to be one long and " frivolous " party in the work of most of the novelists that figure in Kiernan's book: Peacock, Beerbohm, Firbank, E. F. Benson, Wodehouse, and Compton Burnett. Kiernan briefly and perfunctorily rehearses Isherwood's and Susan Sontag's characterizations of camp in an introductory chapter, then proceeds to offer a series of plot summaries accompanied by rather insipid demonstrations that each of his authors is, in his or her way, a "master of the camp novel." Camp, a more complex phenomenon than most of its chroniclers seem to have realized, still awaits its Empson to anatomize its varieties with the authority and restless intelligence he brought to his study of pastoral.


Human T-cell leukemia virus type I (HTLVI) is an etiological agent of adult T-cell leukemia and has a unique sequence, pX, that contains four possible open reading frames, I-IV. p40' was previously identified as the gene product of frame IV (x-lor) and was suggested to mediate transcriptional trans-activation of the viral long terminal repeats. We have identified twopX gene products, p27"" and p21'X-, encoded by frame HI, which mostly overlapped frame IV. These proteins were detected with rabbit antiserum against the synthetic peptide predicted from the 3' end of frame II. p27xis phosphorylated in cultured cells, and the phosphoprotein (pp27x) is localized in nuclei; some pp27'-I was tightly bound to nuclear components. p27x-m was detected in a number of cell lines that express other viral antigens, including a cell line previously reported to express only p40' as a viral protein. The function(s) of p27x-m and p211-rn is not known, but the tight binding of pp27x-m to nuclear components suggests that it is associated with regulation of viral gene expression. The human T-cell leukemia virus type I (HTLV-I) is an exogenous human retrovirus (1-3), associated with adult T-cell leukemia (ATL) (3-6), and an etiological agent ofATL (7). HTLV-I, however, appeared to contain no typical retroviral oncogene derived from cellular sequences (8). Integration of the provirus into primary leukemic cells is not specific to any particular site on the chromosomal DNA (9), and thus the mechanism of leukemogenesis by HTLV-I was concluded to differ from the promoter or enhancer insertional activation of the cellular oncogene. Thus, a virally coded trans-acting factor(s) was postulated to explain the leukemogenesis. On sequence analysis of the proviral genome of HTLV-I, an extra sequence, pX, that contains four possible open reading frames, I-IV, was found between the env gene and the 3' long terminal repeats (LTR) (8) (Fig. 1). Frame IV (x-lor) of the pX region was reported to encode a protein of 40 kDa (p40x) (10, 11), 41 kDa (12), or 42 kDa (13). This p40" was suggested to a trans-acting factor that activates transcription from the LTR (14, 15); that is, the pX gene would be required for efficient expression of the viral gene. Similar pX sequences and proteins were also found in HTLV-II (16, 17), bovine leukemia virus (18, 19), and simian T-cell leukemia virus type I (20-22). Thus, the pX sequences seem to function generally in viruses of this group. Here we report the identification of proteins pp27x-iII and pp21X-l"" encoded by frame III in thepX sequence ofHTLV-I, demonstrating the multifunctional property of the pX sequence. We show that p27""I is phosphorylated and binds to nuclear components. Our findings suggest that these proteins may play a regulatory role in the viral gene expression that is associated with the transforming activity of HTLV-I in vivo and in vitro. MATERIALS AND METHODS Cells. MT-1 and MT-2 (23), HUT-102 (24), and Hayai (a gift of H. Sato, Kyushu University) are human T-cell lines infected with HTLV-I, and TARL-2 (25) is a rat T-cell line infected with HTLV-I. HOS and HOS/MT-2 (26) are uninfected and infected human osteosarcoma cell lines (obtained from H. Hoshino, National Cancer Center, Tokyo). Cell lines CEM and MOLT-4 are uninfected human T-cell lines, and HL-60 is a human myeloblastoid cell line. All lymphoid cell lines were maintained in RPMI 1640 medium containing 10% fetal bovine serum, while HOS and HOS/MT-2 cells were cultured in Dulbecco's modified Eagle's medium supplemented with 5% fetal bovine serum. Antisera Against Synthetic Peptides. Oligopeptides corresponding to the carboxyl terminus encoded by each open reading frame in thepX region were synthesized chemically, and rabbits were immunized with the conjugated peptides as described (27, 28). The synthesized peptide corresponding to the C terminus encoded by frame III (peptide III) was Pro-Ser-Pro-Gly-Pro-Ser-Cys-Pro-Thr. Analysis of Viral Proteins. For isotopic labeling of proteins, 106 cells were incubated with 200 gCi (1 Ci = 37 GBq) of [35S]cysteine for 6 hr in 1 ml of RPMI 1640 medium without cysteine, and 1.5 x 106 cells were incubated with 0.5 mCi of [32P]phosphate in 1 ml of phosphate-free RPMI 1640 medium for 3 hr. Cell extracts were prepared by lysis of cells in RIPA buffer (50 mM Tris-HCl, pH 7.5/150 mM NaCI/0.1% NaDodSO4/1% (wt/vol) Triton X-100/1% sodium deoxycholate). For 32P-labeled cells, the RIPA buffer contained 2 mM EDTA, 10 mM NaF, 1 mM phenylmethylsulfonyl fluoride, and 0.1 unit of aprotinin/ml. Immunoprecipitation, gel electrophoresis, and blotting analysis were performed as previously (27). Fluorescence Staining. Cells were precipitated onto glass slides by centrifugation at 1500 rpm for 5 min and fixed in acetone at room temperature. The cells were incubated with pretreated rabbit antiserum against peptide III and then with fluorescein-conjugated anti-rabbit immunoglobulins. The antisera were preadsorbed for 2 hr with excess uninfected acetone-fixed cells. Subcellular Fractionation. HUT-102 cells were lysed in buffer containing 0.5% Nonidet P-40, 10 mM Hepes (pH 7.5), 0.5 mM CaCl2, and 1 mM MgCl2 and centrifuged at 800 x g Abbreviations: HTLV-I, human T-cell leukemia virus type I; ATL, adult T-cell leukemia; LTR, long terminal repeat(s). tOn leave from the 2nd Department of Internal Medicine, Kumamoto University, Japan. 8359 The publication costs of this article were defrayed in part by page charge payment. This article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. §1734 solely to indicate this fact. 8360 Biochemistry: Kiyokawa et al. for 10 min. The supernatant was used as the cytoplasmic/membrane fraction; and the pellet was washed three times with buffer and used as the nuclear fraction. For further fractionation, the nuclear fraction was washed with 10 mM Hepes, pH 7.5/0.3 M NaCl/1 mM EDTA and centrifuged at 800 x g for 10 min to remove loosely associated proteins (29). The pellet was suspended in 10 mM Hepes, pH 7.5/2 M NaCl/4 M urea at0C for 30 min and then was centrifuged at 100,000 x g for 90 min; the final pellet containing DNA was sonicated for 2 min in RIPA buffer for solubilization of tightly


Hiatal hernia (HH) is one of the most common digestive diseases in the clinic. Due to the lack of specificity of clinical symptoms with the high incidence and recurrence rate, HH seriously affects the quality of the patients' life.The pathogenesis of HH is not clear, and the increase of abdominal pressure is considered to be one of the main reasons. The study found that there is obvious collagen metabolism disorder in the tissues around the patient's gastroesophageal junction, and the collagen involved is the main risk factor for HH. This disorder can lead to weak tissue structure and reduced strength, and promote the formation and recurrence of HH based on increased abdominal pressure. Biochemical factors associated with collagen metabolism can be a potential risk factor for HH. This article aims to summarize the potential risk factors of HH and collagen metabolism at home and abroad, and lay a theoretical foundation for further study on the pathogenesis of HH.


We investigate the effect of financial development on the formation of European corporate groups. Because cross-country regressions are hard to interpret in a causal sense, we exploit exogenous industry measures to investigate a specific channel through which financial development may affect group affiliation: internal capital markets. Using a comprehensive firm-level data set on European corporate groups in 15 countries, we find that countries with less developed financial markets have a higher percentage of group affiliates in more capital-intensive industries. This relationship is more pronounced for young and small firms and for affiliates of large and diversified groups. Our findings are consistent with the view that internal capital markets may, under some conditions, be more efficient than prevailing external markets, and that this may drive group affiliation even in developed economies. This paper was accepted by Bruno Cassiman, business strategy.


Todays most compelling virtual reality experiences shift the users viewpoint within the virtual environment based on input from a head-tracking system, giving a compelling sense of motion parallax. While this is straightforward for computer generated scenes, photographic VR content generally does not provide motion parallax in response to head motion. Even 360° stereo panoramas, which offer separated left and right views, fail to allow the vantage point to change in response to head motion.


Review of: Medical and Healthcare products Regulatory Agency. Denosumab for giant cell tumor of bone: risk of clinically significant hypercalcaemia following discontinuation. Drug Safety Update 2018;11(11);2.