Abstract This essay reflects on ways to equip teacher candidates so they are not only prepared to answer tough questions, but are educated for the linguistic and literacy challenges of today's classrooms. We recognize that with an ever-growing majority minority population, it is time to change the teacher preparation system, and to support current teachers and the preparation of future teachers for the field; these changes need to be soon and are imperative.


The study site is in the ponderosa pine type at an elevation of 8,300 feet near Vallecitos, New Mexico. Before reseeding it was typical of pine openings which, when deteriorated, support only a sparse stand of native vegetation but have a high forage-producing potential. Principal native plants, occupying most of these deteriorated openings, are Kentucky bluegrass (Pea pratensis), winter redtop (Agrostis hiemalis), blue grama (Bouteloua gradis), rabbitbrush (Chrysothamnus spp .), and pingue (Actinea richardsoni). Soil is a deep loam, well drained, with high water-holding capacity. Average annual rainfall is about 22 inches. In August 1946 the following species were planted in quarter-acre plots, randomized in three blocks: Crested wheatgrass (Agropyron cristatum), bluestem wheatgrass (A. smithi), slender wheatgrass (A. trachycaulum), tall oatgrass (Arrhenatherum elatius), smooth brome


ABSTRACT. Dengue Hemorrhagic Fever (DHF) is a disease caused by the Dengue virus and transmitted by the bite  of  Aedes  sp.  In  2009-2010  in  the  District  Banjarnegara  dengue  cases  increased.  In  2009-2010,  in Banjarnegara district which reported  increased of DHF cases. Research objectives were  to obtain  information on water reservoirs (TPA) as a breeding Ae. aegypti and Ae. albopictus by type and basic materials, landfill as a breeding Ae. aegypti and Ae. Dengue virus positive albopictus species and basic materials. The objective of this study was to get information about containers (TPA) as a breeding places of Ae. aegypti and Ae. albopictus and which Dengue  virus  infection  based  on  their  types  and main material.  The  study  was  conducted  in  Kuta Banjarnegara  and  Parakan  Canggah  sub  district,  Wanadadi,  Klampok,  Singamerta  dan  Tapen  village Banjarnegara district  in May  to Agust 2012. Larval survey were done around 100 meters of DHF cases with  local transmission. Bath, buckets, and refrigerator tray were breeding place type of Ae. aegypti which more founded. Indoor container and used goods were breeding place of   Ae. aegypti infected with Dengue virus. Buckets, old tires, used goods and leaf midrib were breeding place of Ae. albopictus which more founded. Refrigerator tray was breeding place of Ae. albopictus infected with Dengue virus. Most of the breeding place Ae. aegypti were made of plastics, ceramics, and cement. Breeding place of Ae. aegypti infected with Dengue virus were made of plastic, ceramic, glass, and  rubber . Breeding place of  Ae. albopictus and  infected with Dengue virus were made of plastic Key words : breeding places, main materials, DHF vector


The yields and product distributions in the oxidation of hydrocarbons (cyclohexane, n-pentane, n-octane, methylcyclohexane, tert-butylcyclohexane, and ethylbenzene), using substituted iron tetraphenylporphyrins and iodosobenzene, are shown to be markedly affected by nature and location of phenyl ring substituents. These substrates were used to measure the activity, regioselectivity, substrate selectivity, and stereoselectivity of the substituted iron porphyrin catalysts. Higher yields are observed with iron porphyrins having bulky substituents near the iron center. Kinetics measurements and concentration studies show that these substituents improve lifetimes by hindering the catalyst's bimolecular self-destruction. Higher yields are also observed with electron-withdrawing substituents. A new iron fluoro-pocket porphyrin shows higher activity due to this electronic effect. Substrate and regioselectivity are also influenced by steric and electronic effects of the iron porphyrin's phenyl ring substituents. Bulky porphyrins also affect the stereoselectivity at the 2-, 3-, and 4-positions in tert-butylcyclohexane oxidation. A mechanism supported by kinetic modeling studies is proposed for the oxidation reactions. 48 references, 14 figures, 5 tables.


A unique design of a composite polymer bushing is introduced and evaluated. A comprehensive test program defined the mechanical and electrical performance of a conical silicone polymer composite bushing. This evaluation also included aging and pollution tests to assess the long-term stability of the new design. Results show that the composite bushing offers technical and safety benefits over conventional porcelain bushings.<<ETX>>


Melt viscosity data were obtained for linear and branched ethylene polymers over temperatures of 150 to 250°C and shear rates of about one to 300 sec−1. A capillary rheometer was employed, and the appropriate corrections were made for the several sources of significant error in shear stress and shear rate. These corrected data were analyzed in terms of the Ree‐Eyring inverse hyperbolic sine relationship for viscous flow. The molecular structure was determined by infrared absorption analyses and molecular weight determinations. The rheological character of these polyethylenes was found to depend on the weight‐average length of the polymer backbone and on the branching. The major contribution to the viscosity depended on the length of the backbone and was associated with the longer relaxation times. An additional contribution to the viscosity depended on molecular segments about equal to the interbranch distance, and was associated with the shorter relaxation times. The temperature effect was found to depen...


This paper analyzes the motion space of pantograph leg mechanism in order todesign and manufacture a quadruped walking robot.We get the space motion of legwith three rectilineal motion in Cartesian coordinates.The paper gives the conclusionthat K_2=1 and K_1(1)should be as large as possible,and gives also three optimizingmotion distance and loction of each actuator with optimizing methods.


Indonesia is a developing country that has various problems, one of which is congestion. Congestion occurs because of the high population, population mobility and poor road facilities. The congestion that occurs in Lumajang Regency is on the Kedungjajang - Ranuyoso road. Congestion is caused by the high mobility of the population to work, and the high side barriers. The purpose of this study was to determine the cause of congestion, the amount of road capacity, and the comparison of the level of road service before and after widening the Kedungjajang - Ranuyoso road. Data collection uses measurement data analysis techniques and documentation that was carried out before and after the widening of the Kedungjajang - Ranuyoso road section. The results showed that the cause of congestion that occurred on Jalan Kedungjajang-Ranuyoso Lumajang was the lack of effective road width, the amount of traffic capacity of the Kedungjajang-Ranuyoso Lumajang road before the widening of the road was 2,291 smp/jam, the amount of traffic capacity of the Kedungjajang-Ranuyoso road Lumajang after road widening is 3069.94 smp/jam, changes in the level of service for the Kedungjajang-Ranuyoso road Lumajang before and after road widening have increased by 2 levels, which originally had a road service level value of "E" to "C" which means the condition the original flow before road widening was unstable current, the speed sometimes stopped, demand was approaching.


Monthly 1994/5 £ Annuel 1994/5 £ Under Any Other Business, Mrs Craik reminded members of the arrangement made with a charitable trust by which the trust had bought the headquarters buildmg, giving the College the option to buy the premises back at a later date. This repurchase was to take place the following day. She pointed out that headquarters is an appropriate outward symbol of a modern profession. She thanked all members who had raised money for the building and for the Disability Information and Study Centre, which is providing an increasing amount of information to support the membership. Mrs Craik spoke of her retirement from office, suggesting that as Chairman she had applied the skills of her profession: she had acted as a catalyst, enabling others to develop projects. As a result, she considered that credit for any achievements during her term of office belonged to all those who had helped create them. She thanked the ViceChairmen, the Secretary and her family for their support during her chairmanship. She passed the badgeof office to Jan Clayton, the new Chairman, and received in exchange her past Chairman's brooch. Jan Clayton appreciated everything Christine Craik had done to raise the profile of occupational therapy during her term of office and hoped that she would now enjoy a rest. The Chairman closed the meeting. Janet Brown, Committee Secretary.


Based on the development of economy and society in Sunan area,this article analyzes the air freight bottleneck which Sunan area faces. Simultaneously the paper combines the experience of domestic and foreign airports construction,emphatically elaborates the necessity of constructing international freight transportation airport in the area.


Indonesia is a country that has a fairly high positive number of COVID-19 in the Asian continent.  In the context of dealing with the virus, this study aims to examine the effectiveness of the government's public relations performance in delivering messages on handling COVID-19 through BNPB Instagram, namely @bnpb_indonesia and images from BNPB.  We use the Social Network Analysis (SNA) analysis method which measures the degree of centrality, closeness centrality and betweenness centrality.  This type of descriptive qualitative research and data collection techniques used is the questionnaire method and involves 112 respondents spread across several regions in Indonesia. The results of our research conducted in April 2020 show that BNPB through the @bnpb_indonesia Instagram account has a good image.  This can be seen from the survey conducted showing that 92.9% knew about the BNPB instagram, BNPB's performance and completeness of information was ranked first out of 14 other reference instagram accounts regarding information related to COVID-19. Then the effectiveness of BNPB's communication through the @bnpb_indonesia instagram account is considered good, it can be seen from the mapping of networks on social media using the SNA method, the results of degree centrality or key actor @bnpb_Indonesia rank first of 14 information references.  Then betweeness Centrality and Eigenvector or the most connected actor is the instagram node @bnpb_indonesia, which is ranked first.


Sensor network software is still in its youth. Due to sensor hardware limitations and the highly specific nature of application domains, existing software is generally poorly structured. We identify data collection, intra-sensor and inter-sensor communication as recurring activities in sensor network applications and propose a software module that abstracts these activities: the stream system. Applications running on the sensors rely on the stream system to disregard the actual implementation details of collecting transducer readings and passing such data to other local or remote computational entities.


The invasion of the Russian Federation into Ukraine, a sovereign country, has been interpreted from different points of view: However, beyond the different opinions, it is clear that this war, which took place in Eastern Europe, has meant a hard blow for global finances, with concrete effects in the increase of fuel prices (gas and coal), in high inflation rates and, according to data from the World Bank (WB, 2023), it has also created an international environment of restrictive financial conditions that hinder macroeconomic recovery in terms of sustainable economic development, after the COVID-19 pandemic. In this order of ideas, using a documentary methodology of geopolitical analysis, which values the geographic conditions of each country, its particular history and its international relations, the objective of the article was to interpret the impact of the Russian invasion of Ukraine on world finances. The results obtained allow us to conclude that the Russian invasion of Ukraine has had far-reaching consequences on world finance. The economic impacts of this invasion have been significant, with disruptions in supply chains, fluctuations in inflation and commodity prices, among others.


As national concern grows over the adequacy of patient safety measures in US acute care hospitals, recent technological advances in infusion therapy may provide a means by which the Clinical Nurse Specialist (CNS) can help promote risk-reduction efforts for patients receiving parenteral care. A class of computerized patient infusion devices that include design features for administration error prevention and data collection (called ''Smart Pumps'') are evolving into a valuable clinical tool that may hold great potential to decrease the rate of medication errors in healthcare facilities.


As a promising alternative to thermoset elastomers, thermoplastic elastomers (TPEs) have attracted much attention because of their unique properties, including processability, reusability and recyclability. The synthesis of TPEs based on olefinic building blocks usually requires the use of long chain α-olefins, multiple steps, and/or multiple catalysts. The concept of using only ethylene as feedstock in a single step is fascinating but also very challenging. In this contribution, we report the synthesis of polyethylene-based TPEs through α-diimine nickel-catalyzed ethylene polymerization. The stress-at-break and strain-at-break values of these polyethylene products could be tuned over a very wide range using different nickel catalysts and different polymerization conditions. Most importantly, products with excellent elastic properties could be generated in the screening process.


We consider the problem of finite sample corrections for entropy estimation. New estimates of the Shannon entropy are proposed and their systematic error (the bias) is computed analytically. We find that our results cover correction formulas of current entropy estimates recently discussed in literature. The trade-off between bias reduction and the increase of the corresponding statistical error is analyzed. PACS: 89.70+c, 02.50.Fz, 05.45.Tp Statistical fluctuations of small samples induce both statistical and systematic deviations of entropy estimates. In the naive ("likelihood") estimator one replaces the discrete probabilities pi, for i = 1, ...,M , in the Shannon entropy [1]


Abstract Seven trifunctional conjugates of Fmoc-protected amino acids with alkynyloxy-substituted coumarins have been prepared and spectroscopically characterized. The coumarin core was either coupled to the α or side chain amino group. This design allows for the linear or branched elongation to peptides or peptidomimetics. The synthetic potential of the conjugates was demonstrated by copper-catalyzed [3+2] cycloadditions to orthogonally protected peptidomimetic products as well as a biotinylated fluorescent amino acid.


The surprising development of higher education and the diversification of social requirement require colleges to do necessary reform of their original personal training mode.Cooperating school with enterprises is a new way of using different educational resources in distinctive environment to cultivate applicable talents proper for the needs of industries and enterprises.It is especially necessary and applicable for the cultivation of science students.From this perspective,it is significant to renew our teaching concept and establish the idea of "integrating the theoretical teaching with practical training";furthermore,it is important to set up the stable base for the cooperation of universities and enterprises,which provides good training platform for facilitating students' practicable ability.While higher education institutes should not discard their ability of heritage and innovation for the purpose of catering to enterprise's needs blindly.Therefore,in order to cultivate university students in an all-around way,institutes should not weaken the function of classroom teaching to strengthen student's practical ability training function.


The present article aims to analyze the implications of the modern technique that make human existence technically possible. Our analysis is based on the works of Hannah Arendt and 1 O presente trabalho foi realizado com apoio da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Brasil (CAPES) Código de Financiamento 001. 2 Doutorando em Filosofia pela PUC/PR – Pontifícia Universidade Católica do Paraná. Mestre em Filosofia pela PUC/PR. Especialista em Ética pela PUC/PR. Graduado em Filosofia pela FAVI – Faculdade Vicentina. Docente na UEMG – Campus Passos. Universidade do Estado de Minas Gerais. Contato: firstname.lastname@example.com 3 Doutoranda em Filosofia pela PUC/PR – Pontifícia Universidade Católica do Paraná. Mestre em Filosofia pela UFSC – Universidade Federal de Santa Catarina. Graduada em Filosofia pela Faculdade São Luiz. Docente no IFC Campus Blumenau – Instituto Federal Catarinense. Contato: firstname.lastname@example.com Problemata: R. Intern. Fil. V. 11. n. 1 (2020), p. 139-159 ISSN 2236-8612 doi:http://dx.doi.org/10.7443/problemata.v11i1.46447 Implicações da tecnificação da existência [Technisierung des Daseins] em Hanna Arendt e Hans Jonas 140 Problemata: R. Intern. Fil. v. 11. n. 1 (2020), p. 139-159 ISSN 2236-8612 Hans Jonas, establishing a dialogue between the two. Through the numerous stages of development of technique and technology, from the seventeenth century onwards we perceive a dependence and subordination of human beings to technology. This threatens the freedom and human integrity of future generations, and confers on a totally postmodern phenomenon that we will call technification of existence [Technisierungdes Daseins], coined by Arendt in July 1954, in his dairy, Denktagebuch. In these terms, we will first analyze how Hannah Arendt understands such phenomena, presenting the steps of technique and technology, its consequences, and what there is political output; in a second moment, from the perspective of Hans Jonas, we will explore the author's contributions on the effects of technology in contemporary society, and explain how his ethical principle of responsibility has the capacity to restrain technological impulses. Finally, after these analyzes, we can affirm that only a policy and an ethics aimed at human interests, are able to face the dangers contained in technology and to safeguard humanity.


Wireless sensors have emerged to offer low-cost sensors with impressive functionality (e.g., data acquisition, computing, and communication) and modular installations. Such advantages enable higher nodal densities than tethered systems resulting in increased spatial resolution of the monitoring system. However, high nodal density comes at a cost as huge amounts of data are generated, weighing heavy on power sources, transmission bandwidth, and data management requirements, often making data compression necessary. The traditional compression paradigm consists of high rate (>Nyquist) uniform sampling and storage of the entire target signal followed by some desired compression scheme prior to transmission. The recently proposed compressed sensing (CS) framework combines the acquisition and compression stage together, thus removing the need for storage and operation of the full target signal prior to transmission. The effectiveness of the CS approach hinges on the presence of a sparse representation of the target signal in a known basis, similarly exploited by several traditional compressive sensing applications today (e.g., imaging, MRI). Field implementations of CS schemes in wireless SHM systems have been challenging due to the lack of commercially available sensing units capable of sampling methods (e.g., random) consistent with the compressed sensing framework, often moving evaluation of CS techniques to simulation and post-processing. The research presented here describes implementation of a CS sampling scheme to the Narada wireless sensing node and the energy efficiencies observed in the deployed sensors. Of interest in this study is the compressibility of acceleration response signals collected from a multi-girder steel-concrete composite bridge. The study shows the benefit of CS in reducing data requirements while ensuring data analysis on compressed data remain accurate.


In this article, the authors examine the social conditions experienced by Asian employees in the workforce, focusing in particular on the lower returns to education that have been documented for both immigrant and U.S.-born Asians. The authors suggest that human capital translates into improved career outcomes by producing greater social capital and hypothesize that those who are more socially and culturally different from the dominant group-such as native-born and immigrant Asians-are less likely to be able to turn human capital into social capital. The theory is illustrated using data from five work teams at the computer services division of a major bank that was staffed with a sizable number of immigrant Asians. The authors found lower returns to education for Chinese and Asian Indians than for European Americans, in terms of managers' assessment of career potential, and also found that education translated into work team centrality only for European Americans.


I'll be honest: when the original AxiDraw came out from Evil Mad Scientist Laboratories in 2016, I thought it was cute but a curiosity. My thought was that if you were going to play around with reintroducing the venerable technology of the pen-and-paper X-Y plotter, why not do something really different, like the iBoardBot remote-controlled erasable miniature whiteboard? And the AxiDraw's US $475 price tag felt steep for a spindly-looking contraption that required the user to manually position each sheet of paper, one at a time.


The hexagonal-hole grid flocculation system is very efficient to deal with high turbidity water of 850 NTU and the color of 2300 PCU. The best conditions are determined through adjusting grid arrangements, concentration and dosage of flocculating agent. When the water velocity of flow is 100 L/h, the grid 2,1,3 module order is the best one. The water turbidity decreased to 19.5 NTU and color to 110 PCU, the removal rate of turbidity is 97.0% and that of color is 95.2%. The average effective mass density ρe of floc is 6066 Kg•m-3, the average equivalent size dST is 346.9µm, the average free-for-speed V is 13.24 mm•s-1, two-dimensional fractal dimension Df is 2.70.


The main purpose of this paper is to analyse the behaviour of the two major Spanish electricity generator companies, Endesa and Iberdrola, in the Spanish electricity daily market, an uniform price market. The analysis based on the dynamic models cannot be carried on in the present case: in Spain, it's difficult to get the accurate costs of production data. Therefore, we have chosen to analyse Endesa's and Iberdrola's behaviour, through econometric analysis, studying the correlation between the hourly system marginal prices and several factors, namely, the amount of energy supplied by technology and company. This paper shows that Endesa's peak load units determine the marginal price system and that fuel and hydrological factors aren't the most significant factors for fixing the marginal price system. This paper also shows, through endogeneity analysis, that the quantities bid by those companies may not reflect production costs, but market strategies instead


Optically active poly(β-peptides) with proteinogenic side chains were synthesized via the polymerization of β-amino acid-N-carboxyanhydrides (β-NCAs) initiated using either NaOtBu or a nickel amido amidate complex. Although most of these low molecular weight poly(β-peptides) have poor solubility in common organic solvents, those that were soluble were found to adopt stable chiral conformations in solution. Poly(N e -carbobenzyloxy-β-L-homolysine) (2f) was observed to adopt a helical conformation in 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP), which could be disrupted by addition of methanesulfonic acid (MSA), a strong denaturing agent. The side-chain deprotected polymers, poly(β-L-homolysine) (3) and poly(β-L-homoglutamate) (4), were found to display pH-dependent conformation transitions in aqueous solution.


"The highest degree of wisdom is integrity." Shimon Peres #quote
Integrity that virtually left the Political Arena these last 20 years.


The annual yield of bifacial photovoltaic systems is highly dependent on the albedo of the underlying soil. There are currently no published data about the albedo of red soil in western Africa. In this study, the impact of the albedo of red soil in Ghana on the energy yield of bifacial photovoltaic systems is analysed. A bifacial photovoltaic simulation model is created by combining the optical view factor matrix with an electrical output simulation. For an exact simulation, the albedo of red soil at three different locations in Ghana is measured for the first time. The average albedo of every red soil is clearly determined, as well as the measurement span including instrumentation uncertainty; values between 0.175 and 0.335 were measured. Considering these data, a state-of-the-art bifacial photovoltaic system with an average of 19.8% efficient modules in northern Ghana can achieve an annual energy yield of 508.8 kWh/m2 and a bifacial gain of up to 18.3% in comparison with monofacial photovoltaic panels. To summarise, red soil in two out of three locations in Ghana shows higher albedo values than most natural ground surfaces and therefore positively impacts the annual yield of bifacial photovoltaic systems.


The effects of two green microalgal strains, Chlorella oocystoides and Chlorella minutissima, on some growth parameters of Zea mays and on some soil physico-chemical properties were studied. The growth mass, chlorophyll content, phosphorous content, and potassium content of maize plants were significantly increased. The increase of other parameters such as plant length, number of leaves, and total nitrogen was not statistically significant. Concerning the studied soil physicochemical properties, the soil total nitrogen significantly increased by inoculation with algal strains. Also the soil organic matter significantly increased with all the used concentrations of the two algae. The pH significantly decreased with 1%, 2.5%, and 5% of C. oocystoides, while there was no significant change with the second alga. [Taha TM and Youssef MA. Improvement of Growth Parameters of Zea mays and Properties of Soil Inoculated with Two Chlorella Species. Rep Opinion 2015;7(8):22-27]. (ISSN: 1553-9873). http://www.sciencepub.net/report. 5


The purpose of this work was to demonstrate the compatibility of Dow Corning's temporary bonding solution with EVG's 850XT universal temporary bonding and debonding platform. The proposed process made use of well-known processing steps and processing modules like spin coating. The process consisted of a release layer (Dow Corning® WL-3001 Bonding Release) and an adhesive layer (Dow Corning® WL-4050 or WL-4030 Bonding Adhesive) using an EVG® 850TB - 300 mm XT frame. Both layers of material were applied by spin coating on the device wafer side. In the frame of this study, silicon carriers were used. Bonding was performed under vacuum at room temperature. A post bonding bake step was applied using a hotplate. After subsequent backside processing steps, the room temperature debonding was performed.


The editorial collaboration of William Keller and Gordon Mitchell*one a professor of international security studies and the other an associate professor of communication*has produced a valuable set of critical essays written by an interdisciplinary mix of scholars in political science, rhetoric, and philosophy about the preventive warfare doctrine underlying U.S. aggression in Iraq. Hitting First offers a frank appraisal of the deliberative pitfalls of cloaking a policy of preventive military aggression in the legitimating language of imminent threat and preemptive military action. Blurring the distinction between preemptive engagement and preventive attack, this book argues, is a nefarious exercise in rhetorical flexibility that undermines national security and world peace. As William Hartung observes, ''preventative war dressed up in the language of preemption'' (p. 218) errs on the side of exaggerating threats and understating the costs of ''a doctrine that would put a hair trigger on potential conflicts worldwide'' (p. 221). This conflation of self-defense and aggression is not just the rogue maneuver of a miscreant state propaganda regime but ultimately a systemic ''discursive failure'' of the broader political culture, ''a lack of rhetorical invention on the part of citizens, journalists, and lawmakers,'' Keller and Mitchell argue (p. 249). Even the disaster of the Iraq war, they suggest, has not discredited the insidious notion of anticipatory self-defense or redirected public policy deliberations toward an alternative national security policy. The document at the heart of the book's analysis is the Bush administration's National Security Strategy paper (NSS 2002), originally released in September 2002 and since updated, which systematically elides the critical distinction between preemption and prevention. That key distinction, as Dan Reiter (among others)


Identifying a good site for groundwater exploration and well siting in hard rock terrain is a challenging task. In hard rocks, groundwater occurs in secondary porosity developed due to weathering, fracturing, faulting, etc, which is highly variable within short distance and contributing to near-surface inhomogeneity. In such situations, topography, geology, hydrogeological and geomorphological features provides useful clues for the selection of suitable sites for borehole drilling. In the present work, geology, Electrical Resistivity Technique (ERT) with schlumberger electrode configuration and Very Low Frequency Electromagnetic (VLF-EM) methods were carried out in the study area. A total of forty eight (48) Vertical Electrical soundings (VES) and eight (8) VLF-EM profiles were carried out in the study area. From the geologic mapping, the area is underlain by granite gneiss, granite and schists. On the basis of resistivity survey, 3 to 5 geoelectrical subsurface layers set-up is found in the study areas. These layers are topsoil, highly weathered zone, semi weathered zone, fractured zone and fresh bedrock. It has also been marked that in some cases the semi-weathered and fractured zones are not distinguished clearly from each other because of similarity in their resistivity values. The anomaly obtained in VLF measurements is an indication of the presence of conductive and fractures zones. The results obtained from inversion of the ERT data are consistent and complementary to the conductivities measured in the VLF-EM surveys and have proved effective in the understanding of the hydrogeology of the study area.


The effect of chemical modification by addition of strontium or sodium on the heat treatment response of 356 alloy has been investigated on both gravity-diecast (permanent mould) and sand cast samp...


This work shows the use of the operating region of a D-STATCOM based on multilevel current-source inverters to define its operating point and its LC filter. A multilevel current-source D-STATCOM model is defined to compute its operating region and obtain a relation between reactive power compensation and the device power losses. Using this relationship the losses costs of the reactive power compensation is computed and used to define a methodology to get an operating point and design the LC as a function of the desired cost for nominal power compensation. The methodology is tested in the design of a 125kVA/380V distribution grid, where simulation results corroborate the analysis, including changes from one operating point to another, in open loop, to show the compensation capabilities, the power topology effort and the grid mains variables with compensation.


This paper discusses the performance of a single-phase induction motor drive under nominal load in a closed-loop vectorcontrolled system. The control strategy to be applied is known as indirect field oriented control. Single-phase induction motor when operating as two-phase motor has its dynamic performance increased. By applying this methods, an induction machine can be analyze and operate similar to the dc machine as this method provides the decoupling effect to the motor. By controlling the d-axis and q-axis current, the speed and torque of the single-phase induction motor can be controlled independently. With the use of a voltage-source inverter, space vector pulse width modulation can be implemented.


Ethics is concerned with the suffering humans cause one another and the related capacity of humans to recognize and address this suffering through the empathetic virtues of sympathy, compassion, and caring (Roberts, 1996). Much suffering throughout history can be related to the problem of "unacceptable" diversity among individuals or groups. Remembering the cruelties of the Nazi exterminations of Jews, slavery in the United States, and discrimination against homosexuals jolts us to awareness of the suffering of those who are "different." A task of ethics, then, is to include, rather than exclude (Post, 1995). One approach to an ethics of diversity for healthcare professionals is a call for intimate listening to the stories of those who are different, who may be unseen, marginalized, and excluded in our health care systems.


The University of Utah's Immersion/Multiliteracy (IM/ML) Program is an outgrowth of the post-WWII movement towards an extension of the area studies model to modern foreign language study. Where the IM/ML program has sought to innovate is in the creation of a first-year language course based on the area studies model. Using a methodology based on the Canadian immersion approach, the IM/ML Program has set as its goal multiliteracy, i.e, the pursuit of intellectually challenging and culturally broadening activities in more than one language. This article describes the pilot IM/ML Program in Spanish in which first-year language students used Spanish-language newspapers and culture/civilizations texts to study the history, geography and current affairs of Latin America. Results of the pilot program indicate 1) that IM/ML students are for the most part keeping up with students in traditional courses with respect to skill development, and 2) that the IM/ML Program holds promise for enhancing the contribution of introductory foreign language study to students' liberal education.


N-Terminal pro-B-type natriuretic peptide (NT-proBNP; 76-amino acid peptide) is cosecreted with BNP and can be measured by automated immunoassay (Elecsys 2010; Roche UK). This is a fully automated electrochemiluminescence "sandwich" immunoassay based on capture (biotinylated) and detection (ruthenium) polyclonal antibodies against NT-proBNP amino acids 1–21 and 39–50 (1), respectively. Reports on in vitro stability are conflicting (2)(3)(4). We assessed the effect of different sample types on measurement of NT-proBNP and evaluated the effect of delayed separation of serum from cells on stability. We compared plasma in lithium heparinate (14 IU/mL of blood; Greiner Labortechnik; cat no. 9045-22-1) and serum in serum separator (SST) tubes from patients attending a heart failure clinic. For sample type comparison, blood from 60 patients was collected into SST and lithium heparin tubes. Blood was also collected in plain glass and SST …


During the excellent Conference on Health Services Research in Europe (http://www.healthservicesresearch.eu/), in the Hague, the Netherlands, in March 2010, a conversation with a compatriot followed the perennial topic 'What is public health research?' On this occasion there was a twist: 'Is health services research also public health research?' We agreed they are both parts of the same activity, and noted that more health services research is done in institutes of public health than in university medical schools. Yet then my colleague said, 'But I would never publish in the European Journal of Public Health . It has the wrong title.'

Also last year was the first Global Symposium on Health Systems Research (http://www.hsr-symposium.org/). The meeting was held in Montreux, Switzerland [where 1400 participants also attended the 2006 European Public Health Association (EUPHA) annual conference, memorably hosted by the Swiss Society for Public Health], with multiple international sponsorship including World Health Organisation (WHO) Headquarters in Geneva and its daughter organization the Alliance for Health Policy and Systems Research. The Global symposium, also an excellent meeting, was very different from the Hague conference. Although held in Europe, its perspective was slanted away from experience in 'high-income' countries. It drew on earlier annual meetings of the Global Forum for Health Research, also WHO sponsored, and including two global ministerial meetings on health research in 2004 (Mexico) and 2008 (Mali). It had a very 'official' character, with most participants (and their 'per diems') being funded by international sponsors or governments, and few participants paying themselves.

How can we develop health services and systems research …


I. Introduction, 1. — II. An analysis of the case for compulsory health insurance, 2. — III. An analysis of the case against compulsory health insurance, 11. — IV. Alternative methods of improving the nation's health, 19.


Taking negative reactive amplificatory circuit and integral circuit as example, the paper introduces the emulational analyzing procedure of Multism2 001, which is helpful for students to study the composition, working principle a nd performance parameter in their learning analogue electronic technology.


Problem statement: After dissolution of Soviet Union, both of political geography system and dominance ideational structure have deconstructed in central Asia region. In year of 1979 with revolution, Iranian actors was accepted the Islamic republic system in their country, so new actors, structure and exigencies were revealed in Iran and central Asia relations, that cause create new challenges in confronting of Islamic republic of Iran government. Our fundamental question in this research is that: How geopolitical constructs have constituted confronting challenges for Islamic republic of Iran in Central Asia region? Approach: Therefore in this study we tried to explain the question in geographical framework and constructivism approach (on ground as constructivism geography). We had utilized qualitative research method and hermeneutic-positivist procedure in this study. As attention implicated question, the purpose of this article is understand challenges how constitute in reason of geopolitical constructs. Results: Differences in geopolitical constructs, between Iran and countries of central Asia region and also being harmonious construct, these countries with the present actors in the region, has caused an opposition in regional anarchic system between IRI and these countries in region and actors in the region and also form of distribution of capabilities between actors which has caused challenges for IRI. Conclusion: For following its goals against, high level fruition enemies of IRI like USA, Israel and Russian, China competitors from distribution of capabilities in national and international caused many challenges and double-deficiency for IRI.


We review recent research on reactions (including dissociation) initiated by low-energy electron bombardment of monolayer and multilayer molecular solids at cryogenic temperatures. With incident electrons of energies below 20 eV, dissociation is observed by the electron stimulated desorption (ESD) of anions from target films and is attributed to the processes of dissociative electron attachment (DEA) and to dipolar dissociation. It is shown that DEA to condensed molecules is sensitive to environmental factors such as the identity of co-adsorbed species and film morphology. The effects of image-charge induced polarization on cross sections for DEA to CH3Cl are also discussed. Taking as example, the electron-induced production of CO within multilayer films of methanol and acetone, it is shown that the detection of electronic excited states by high-resolution electron energy loss spectroscopy can be used to monitor electron beam damage. In particular, the incident energy dependence of the CO indicates that b...


comparing stromal cell antigen (BST2) the AHLSC of pre-symptomatic/symptomatic on et explored the β -sitosterol β -D-glucoside (BSSG) model with a focus on motor function, and associated immunohistochemical markers. They used BSSG modeling to detect behavioral changes and immunohistochemical markers in mice. The results revealed that no changes in behavior were observed at any time point. Animals were processed for immunohistochemistry markers of substantia nigra integrity after behavioral testing. In the substantia nigra, immunohistochemistry indicated no alterations in the microglial marker Iba1 or the dopaminergic integrity marker tyrosine hydroxylase (TH) at any assessment point. The lack of any behavioral or immunohistochemical changes across groups implies an inability to duplicate earlier findings.


The well-known principle of the direct torque control applied mainly to squirrel-cage induction motor drives can be generalized and applied to other machines, quantities, converters and systems. These are: other AC machines (double-fed induction and permanent magnet synchronous machine), active and reactive power, direct power control of the line side converter, direct controls of both of the converters in a DC link inverter. The idea is the same for all of them and can be generalized. Looking deeper into the operation of the direct controls, some special effects can be found: different resulting error bands and switching frequency in different operation modes of the converter, large delay in reference tracking. These can badly affect the operation of the control: larger (not the expected) error, larger switching frequency, slower control. Methods are given against them: modified switching tables, increasing the number of sectors, selecting proper sector orientation.


This paper introduces a model that can be used to share network capacity among customers under different traffic conditions. This model is suitable for multiservice networks, such as the Internet, to support connections of given duration that require a certain quality of service. We study different types of network traffic mixed in the same telecommunication link. A single link is considered as a bottleneck and the goal is to find the customer profile that maximizes the revenue of the operator.


The demand to have secure environments for systems' information on cloud systems is arising since this should be more secure and far away from our systems damage disasters and data corruption. The dream became real with the cloud computing. Cloud computing is being more famous and used especially in the enterprises where the cost matters. These enterprises can reduce IT costs by using cloud computing services. Most of the enterprises that don't use cloud computing have a fear of the platform security and the information security. The users always seek for verifying the confidentiality and integrity of their data and computations before using cloud computing. Many researches have been established in these two fields for the infrastructure, platform security, data confidentiality and integrity. This paper, presents two examples for platform security and a comparison between three techniques for how can users secure the data and computations, at cloud environment, to keep the confidentiality and integrity. The ultimate goal of providing such a comparison is to encourage enterprises and users to use the cloud storage systems on secure infrastructures and platforms that maintain their customers/own data privacy.


The aim of the present article is to identify the strategies of two Italian painters from the last years of the Nineteenth Centrury to represent the death of composer Carlos Gomes that took place in Belem city, in 1896. The use of this "representation" by the Art Museum of Belem in the narratives of its collection is also object of study. For that, we reflect about the narrative procedures of the "historical painting" and its documental employ within the context of a tradition of reading "a" story from the establishment of the "gomesian" myth.


We present a simple numerical method to solve the vertical flow equation of water through unsaturated soils. The method is based on the approximation K = Ko·eaψ and can be used for any range of soil moisture. The method uses the behavior of the exponential function in an integrated flux formula. The resulting numerical scheme is extremely easy to program and runs about as fast on microcomputers as implicit techniques do on large computers. Mass conservation is also excellent.


The bending strength was studied for load‐to‐grain direction at angle of 90° and load‐to‐annual tree ring direction at angle of 45° of almost 700 years old subfossil elm wood from Sava riverbed. Elm wood is widely used because it is solid and hard regarding its weight. However, due to the Elm Dutch disease and mass drying of elm trees in 1950s, nowadays it is almost impossible to find in natural forest stands of south‐eastern Europe a tree of reproductive age. The value and uniqueness of the studied material lies also in the fact that the subfossil elm wood is even rarer than the recent one, and is highly appreciated for its aesthetic and mechanical qualities. Bending strength has been determined by a three‐point bending test. The mean bending strength value is within the limits for recent elm wood. This investigation has shown that such load‐to‐annual ring direction has almost 20 % higher value for bending strength than for loads applied to the longitudinal‐tangential surface (angle of 0°) and to the longitudinal‐radial surface (angle of 90°). This proves that the ring orientation plays an important role in the measurement of mechanical properties of elm wood and that the measurement of the angle of 45° should always be considered for investigation of bending strength.The coefficient of determination of Weibull functions has been close to value of 1, so it has been concluded that the measured bending strength follows Weibull distribution.


We present a new scenario for the formation of cool cores in rich galaxy clusters, based on results from recent high spatial dynamic range, adaptive mesh Eulerian hydrodynamic simulations of large-scale structure formation. We find that cores of cool gas, material that would be identified as a classical cooling flow on the basis of its X-ray luminosity excess and temperature profile, are built from the accretion of discrete stable subclusters. Any "cooling flow" present is overwhelmed by the velocity field within the cluster; the bulk flow of gas through the cluster typically has speeds up to about 2000 km s-1, and significant rotation is frequently present in the cluster core. The inclusion of consistent initial cosmological conditions for the cluster within its surrounding supercluster environment is crucial when the evolution of cool cores in rich galaxy clusters is simulated. This new model for the hierarchical assembly of cool gas naturally explains the high frequency of cool cores in rich galaxy clusters, despite the fact that a majority of these clusters show evidence of substructure that is believed to arise from recent merger activity. Furthermore, our simulations generate complex cluster cores in concordance with recent X-ray observations of cool fronts, cool "bullets," and filaments in a number of galaxy clusters. Our simulations were computed with a coupled N-body, Eulerian, adaptive mesh refinement, hydrodynamics cosmology code that properly treats the effects of shocks and radiative cooling by the gas. We employ up to seven levels of refinement to attain a peak resolution of 15.6 kpc within a volume 256 Mpc on a side and assume a standard ΛCDM cosmology.


As the rapid development of e-business application, it is essential to solve its security problems. Currently, resolving the e-commerce security issues mainly relies on the security system which concentrates on the digital certificates. In college, the students would be taught to master the application of digital certificates through experiments, but there are still many problems in the experiment. This article briefly describes the whole process of digital certificates experiments, focusing on analysis of common problems in experiments, and provides the corresponding solutions.


Based on study of progressive die process for the partition board pays,the progressive die designed by UG-PDW was introduced.And the main design program of layout,simulation and mold structure were expounded.Then the method and procedure of the multi-position progressive die were designed based on PDW.Proved in practice,this method improves the design efficiency,shortens the mold manufacturing period,optimizes the process and makes the die run smoothly,and the quality of its products is reliable.


Trees of the olive (Olea europaea L.) cultivar Zalmati grown in Zarzis (Mednine) with different main climate traits (temperature, precipitation, humidity, and wind) were studied for 3 years to evaluate the impact of climate on the quality of olive oil. The effect on quality indices, free fatty acids, peroxide value, UV spectrophotometry, pigment content, and phenol and O-diphenol concentrations, of the three harvesting periods was considered. Linking to the purity parameters (fatty acid, triacylglycerol, total phenols, and tocopherols composition), our results showed a trivial reduction in fatty acid composition and polyphenols content caused by the high temperature. In fact, precipitation strongly affects the pigment content, which showed a significant decrease during rainy seasons. Nevertheless, principal component analysis allowed us to highlight the correlation between parameters and indicates that 57.8% of the variation of monounsaturated fatty acids (MUFAs), polyunsaturated fatty acids (PUFAs), MUFA/PUFA, α-tocopherol, C 18:1, and C 18:2 amounts was explained by the mean temperature.


Introduction: Hospitals as the centers that consume the most resource of health system, based on their function have difference performance and efficiency. The purpose of this study was to assess the efficiency of hospitals in Semnan province using data envelopment analysis with input nature. Methods: This research is an applied one in terms of purpose and a survey and descriptive one in terms of nature. The data envelopment analysis technique, the cover form, and the input nature with the assumption of variable returns versus the scale, was used. relative efficiency of 13 hospitals in Semnan province were analyzed between 1394and 1395. The necessary information was extracted from scientific documents, and the data related to input and output indices were collected from vice chancellor for Administration and TUMS. The collected data were then analyzed by GAMS. Results: The averages efficiency of hospitals, during the years 1393-1395, were 0.81, 0.82, and 0.76, respectively. 0.38 percent of hospitals had constant return to scale, 0.38 percent had decreasing return to scale and 0.23 percent of them had increasing return to scale. Therefore, 0.76 percent of hospitals did not have the capacity to develop beyond the status quo. Conclusion: Most hospitals are not efficient. The performance of inefficient hospitals can be improved following the patterns used by reference hospitals and also by better financial and human resources management. This research introduces a functional pattern to senior managers of the health sector, enabling them to have more accurate planning for capacity development and resource saving.


PURPOSE: A motion information prediction method between improved layers for scalable video coding and a device thereof are provided to obtain motion information of a reference layer from various sample positions, thereby increasing motion information prediction efficiency corresponding to a difference of an image size and a difference of an encoding structure. CONSTITUTION: An encoder obtains a sample position of a reference layer corresponding to a reference sample position of a current encoding object prediction unit of an improved layer. The encoder uses at least one of motion information of a prediction unit and surrounding prediction units for motion information encoding of the current encoding object prediction unit.


The starting point for the discussion about ethnological cartography is the result of the research of the traditions of lighting bonefires among two Croatian ethnic groups, Bunjevci and Sokci, inhabiting the region ofBacka in Voivodina, SR Yugoslavia. The research has well pointed to the deficiencies , as well as to the advantages, of the data in the questionnaires of the Ethnological Atlas and its appliance. The result of the research has also stimulated the author to discuss the mistakes and weaknesses that caused slowdown in the developement of the ethnological cartography and its full practical achievement. The author assumes the technique of the ethnological cartography to be theoretically and methodically well conceived procedure, but its realization has failed for many reasons. The essence of the problem has been touched and partly discussed, with the aim to urge the ethnologists to discuss it more thoroughly in order to define the right place of the ethnological cartography in the Croatian ethnology and to decide about its future existence. Only after discussion on that level, according to the authors opinion, there might be enough arguments for the ethnological cartography to gain the institutional rank in Croatia again, which would be the only right solution for the ethnological cartography and the only possible way of its appropriate practical appliance. The problem of the ethnological cartography is finally discussed in the wider context of the position of the Croatian ethnology as a science.


Duty Roster Management System is system that is developed to help staffs by produce the updated work scheduler and it make the staff work very hard. Through this system, staffs and Department Heads can know the work load and off day among the staff is same.And also this system might not have a duplicated shift or offday, coz it will apply the staff.The system also can send SMS to the supervisor and the person who have been selected go to work.This system will help the dept head to make an informed decision faster by referring to the company database through an online system without having to fill out due to the supervisor is on leave.This system was developed using the "waterfall" methodology, in which the development work was done in a bottom-up fashion. The framework of the system is based on MS SQL 7.0 as the database system and PHP 7.0 as the decision support system.


Thermally induced current in low noise polymeric coaxial cables can introduce significant errors in certain applications. For e-beam crosslinked polymeric cable, the thermally induced current signal can be as high as 1 nA/m. The origin of such thermally induced signals is explained, based on the change of morphology and dielectric polarization as a function of temperature. The results of measurements carried out on three types of cables over a wide range of temperature are in good agreement with numerical simulations which involve the nonlinear thermal properties of the cable materials.


Ship noise interference is one of the major interference in offshore seismic data collection. In most cases, the ship noise interference has the property of lateral wave, and hence the traditional processing technique for eliminating linear regular inferences fails to suppress it. By employing the spatial domain transform method, the regular ship noise interference in the common shotpoint domain can be converted into stochastic interference in the common deviation distance domain, and by using the popular technique for suppressing stochastic interference, the aim of suppressing ship noise interference can be attained. The examples of suppressing ship noise interference are also given in this paper.


SUBTITLE: EWING WANTS NAVY BUSINESS PRACTICES TO CHANGE, TURN THINGS AROUND AT NORSHIPCO, AND SAVE THE AMERICAN TAXPAYER $100 MILLION TO BOOT.


Abstract Introduction: Retroperitoneal schwannoma is rarely excised laparoscopically, and the laparoscopic management of retroperitoneal neural tumors remains controversial. We herein report a case...


Supercapacitors are considered to be very attractive energy storage devices, as they have high power density and cycling stability. 1, 2 However, supercapacitors are still not capable of delivering high energy densities comparable to those of lithium ion batteries, and this drawback restricts the use of supercapacitors mainly to high-power applications such as emergency power supplies, hybrid bus, and portable power tools. So,how to significantly increase the energy density of the cell is the biggest challenge facing electrochemical capacitors. The energy density (E) of supercapacitors depends on the cell potential (V) and capacitance (C), based on E= 1/2(CV 2 ). 3


Optical encoders have been used for decades as displacement measuring devices. As far as image measurement is concerned, CCD and CMOS are gradually used in metrology fields. In practice, performance of image ultraprecise optical encoders are related to environmental temperature, humidity, data processor speed, and vibration, thus measurement precision of encoders will be affected, and these factors limit their usage scale. Among these factors, the vibration is the largest effect factor. Here, a new experiment system was built to study vibration effect of measurement. Experiments indicated that the effects of vibration mainly exist in two aspects. Firstly, vibration induced deformation of glass grating, so distance of adjacent grating lines got uncertain. Secondly, random vibration affected CMOS image sharpness, and it reduced accuracy of encoding and decoding. Finally, some methods are provided to reduce the vibration of the grating encoder.


: WAAM is a form of Direct Energy Deposition that 3D prints metal parts using an arc welding process. Unlike other conventional AM methods, WAAM uses an electric arc to melt metal wire. The procedure is guided by a robotic arm, where the shape of the product is created on a substrate material. When the wire is melted, it is extruded into beads on the substrate. The beads bind together, forming a coating of metal. The process is repeated in a layer-by-layer fashion until the required metal part is finished. In the present study, a rectangular slab of dimensions 300 x 200 x 20 mm 3 was fabricated using 4043 MIG filler wire via wire arc additive manufacturing (WAAM). The effect of welding current (heat input) on the weld microstructure and mechanical properties of 4043 WAAM alloy was investigated. Three weld joints were produced by varying the welding current from 140 to 160 A for the other welding parameters kept at constant value. The experimental findings reveal that all the weld joints were defect free and the strength of the weld decreased for the increase in the welding current. A highest joint strength of 120 MPa (119% of the base WAAM strength) was achieved in case of lower heat input(140A) weld joint. The significant strength is due to presence of more refined equiaxed dendritic microstructure and smaller size of fusion boundary. The toughness of the weld joints were 10, 11 and 12 Joules for low, medium and high heat input respectively. The toughness of the weld joints shows an increasing trend for the increase in the welding current. More softening of the weld joint has resulted in higher ductility and toughness. The results of pitting corrosion studies reveal that overall, a better and similar corrosion behaviour was achieved in all the weld joints, owing to presence of more Si in the Al matrix. The difference in the heat input and grain coarsening in the weld microstructure has attributed to variation in the corrosion resistance of the weld joints. However, the corrosion resistance of the weld joints are within the acceptable limit of the industry standards.


To explore the configuration and distribution of the digestive tube argentaffine cell of Anura Amphibians. Method: By taking the digestive tubes of Bufo Bufo gargarians and Rana nigromacutala and Rana limnocharis were routinely embedded with paraffin and sectioned in series and stained with improved Long Guikai's and Fortana - messon' s silve staining method, The configuration, distribution and delsity of the digestive tube argentaffine cells were observed and sun eyed. Results and conclusion: The argentaffine cells arc distrib- uted in epithelium and gland of tunica mucosa from the ending part oesophagus to cloaca. The density of argentaffine cells is wavy from the beginning to end of digestive tube, it has three peaks in cardia, pylorus and the end of inteslinum tenue. The configuration and volune of the argentaffine cells are related with their position.


Real-time simulations of modern power electronic systems require very short frame times of the order of a few microseconds or less. Recent research has developed techniques using digital signal processors or field-programmable gate arrays to meet this need. Integrating these high-speed simulations in a complete power system simulation often requires multi-rate simulation techniques and integration of the high-speed platforms with conventional platforms based on a real-time operating system such as a real-time version of Linux.


The aniou UV-curing water soluble prepolymer was synthe sized with toluene diisocyanate, dihydroxy compound, dihydroxyalkyl carboxylic a cid and polyurethane acrylate. The structure of the prepolymer was characterized by infrared spectroscopy. And some influencing factors of the coating film were studied. Some tests show that the synthetic prepolymer UV cured has good coating film behaviour.


A new thermodynamic framework for microplane formulations is summarized. A free-energy potential is defined at the microplane level, such that its integral over all orientations gives the standard macroscopic free energy. From this simple assumption it is possible to derive in a unique way consistent microplane stresses and their corresponding integral relation to the macroscopic stress tensor. These new relations are discussed and compared to the traditional approach to microplane model using intuitively defined stresses and the PVW.


The present invention relates to an omnidirectional wheel mechanism having a dual offset structure and an omnidirectional mobile robot using the same. An omnidirectional wheel mechanism having a dual offset structure according to the present invention includes: a caster module located below the traveling body traveling by the omnidirectional wheel mechanism; A traveling motor and a steering motor installed in the traveling body; A steering shaft assembly configured to connect the driving body and the caster module so that the caster module is rotatable about a steering shaft with respect to the driving body, and rotate the caster module about the steering shaft according to the rotation of the steering motor; A caster wheel rotatably installed on the caster module, the center of rotation of the caster wheel being spaced apart from the steering shaft by a driving direction offset and a lateral offset, respectively, in a driving direction of the caster wheel and a rotation axis direction of the caster wheel; Installed in the module—and; And a travel shaft assembly configured to transmit the rotational force of the travel motor to the caster wheel so that the caster wheel rotates according to the rotation of the travel motor. Accordingly, the traveling motor and the steering motor are installed in the traveling body and the dual offset is applied, thereby realizing the holographic driving capability and the omnidirectional traveling capability.


This article addresses how Andalusian universities implement educational, research and dissemination policies and actions in the field of social responsibility and international development cooperation. To the end, the authors analyze the communication policy of the websites of Andalusian public universities, with a special emphasis on the keys and shortcomings as regards the dissemination of information about these two issues.


Simultaneous multithreading (SMT) is a unique computer architecture feature to increase the pipeline utilization and therefore, increase the instruction throughput. It improves instruction level throughput by simultaneously filling both vertical and horizontal super-scalar pipeline slots that are left unfilled by native threads. So far SMT has been implemented in hardware. However, hardware SMT implementations have its limitations. First, it is complex and expensive to implement—only higher-end processors are equipped with it even though lower-end processors have same pipeline design as the higher-end variants and might also benefit from it. SMT also introduces great power/energy and area overheads. Moreover, being a hardware feature, SMT is limited by the range and depth of instruction analysis that it can afford at execution time, therefore it is unlikely to benefit from high-level software knowledge about instruction mix and might lose many improvement opportunities. In this paper, we address the limitation of the hardware-based SMT and introduce CSSMT: Compiler based Software Simultaneous Multithreading (SMT). The main contribution of CSSMT is that it exploits high- level program profiles to purposefully "re-mix" instructions from multiple programs to better fill vertical and horizontal super- scalar pipeline slots so that the overall throughput is improved. Furthermore, CSSMT is a software-transformation technique that enables SMT at software level during compilation time. Therefore, it can help overcome the limitation of the hardware-based SMT implementation and is more portable. We test CSSMT with programs from SPEC2006 and NAS benchmarks and achieve up to 12% speedup of execution time (30.7% improvement in terms of multi-program throughput).


A selective encryption algorithm based on Run-length Encoding with no loss is proposed in this paper.First the bitplane is run-length encoded,and then the short run-length,which is not important to the image is filtered off,thus reducing the encryption content.The selected content is encrypted with AES or stream cipher based on LFSR.Finally the security of the algorithm is analysed,and it is proved to be a secure and fast algorithm.


Based on the analysis that industry intergrowth is the effective way of the development of circulation economy in mine area,this paper systemically identifies and divides the main chain-net models of mine area industry intergrowth into four kinds:main leading,parallel,attaching and mixture form;summarizes their features,and takes cases' study.Meanwhile the paper puts forth further conceptions: as the continuous development of industry intergrowth models,the main model applied in the mine area is the mixture model which the above several models co-exist.


Series Editors' Preface. Preface. List of Figure. List of Tables. 1. Locating the New Deal. 2. The Geographies of Worklessness. 3. Local Disparities in the Performance of Welfare-to-Work. 4. Welfare to Work in Local Context. 5. A Geography of Mismatch? Employers, Jobs and Training. 6. Localising Welfare to Work?. 7. Conclusions. Notes. Bibliography. Index.


Last November, the U.S. Food and Drug Administration granted accelerated approval to a new targeted therapy for non–small-cell lung cancer (NSCLC) called AZD9291. The drug had a remarkable 61% response rate among patients harboring the epidermal growth factor receptor T790→M mutation, which confers resistance to frontline treatment. Also, the approval was based on singlearm phase II data instead of results from a randomized clinical trial. In this experience, many experts see the best hope for the future of cancer drug development: one based on streamlined evaluations of targeted treatments given to patients who are most likely to experience clinical benefits. "We're no longer interested in big randomized studies that produce statistically significant results that aren't clinically meaningful," said Gary Middleton, M.D., a professor of medical oncology at the UK's University of Birmingham. "We're looking for big gains from targeted drugs in single-arm studies that look for high levels of activity."


Density functional calculations in supercells are used to investigate antisite point defects in YAlO{sub 3} and LuAlO{sub 3}. It is found that antisites consisting of an Al on the Y(Lu) site and those consisting of an Y(Lu) on the Al site both have low energy with respect to binary oxide reservoirs. Defects containing Al on the A site yield electron traps at 0.4-0.8 eV below the conduction band edge, while Y(Lu) ions on the Al site do not. Based on this it is suggested that growth conditions that avoid Al on the A site may reduce the number of electron traps in these materials.


We propose in this paper a new approach for the dynamic enforcement of Web services security, which is based on a synergy between Aspect-Oriented Programming (AOP) and composition of Web services. Security policies are specified as aspects. The elaborated aspects are then weaved (integrated) in the Business Process Execution Language (BPEL) process at runtime. The main contributions of our approach are threefold: (1) separating the business and security concerns of composite Web services, and hence developing them separately (2) allowing the modification of the Web service composition at run time and (3) providing modularity for modeling cross-cutting concerns between Web services. We demonstrate the feasibility of our approach by developing a Flight System (FS) that is composed of several Web services. First, a RBAC (Role Based Access Control) model for the flight system, which we called RBAC-FS, is elaborated. Afterwards, the Web services that implement the security features are developed. Finally, the BPEL aspects that integrate the security functionalities dynamically into the BPEL process are created. The devised aspects realize the elaborated RBAC-FS model and provide authentication and access control features to the flight system. Case studies and experimental results are also presented to defend our propositions.


The general account of each circary is followed by a particular account of each abbey, briefly recounting the circumstances of its foundation and dissolution, stating its dedication and paternity, together with the names of its appropriated churches, and describing the present state of its buildings. Then there is a note on its surviving archives and a useful bibliography. Finally there is a list of abbots. No work of this kind could be compiled without some errors and omissions, but Fr. Backmund's zeal for accuracy has led him to visit libraries in every part of Europe in order to verify his references, and both in scope and in scholarship his work must be regarded as a major contribution to the history of European monasticism. In writing it in Latin, he has chosen a language which will be intelligible to all medievalists of whatever nationality, and if his latinity is, as he readily confesses, parum classica, there are few historians who will presume to find fault with it on that account.


The combination of the internet and digital music challenges the present copyright institution, and people are declined to look for the protection from the traditional law in digital circumstance. But the functional variation of the music copyright institution demolishes a balancing of interests,that is to say the institution of the music copyright protects the interest of the middlemen that should have protected the interest the writers of music. So this article analyzed this institution and try to expand the institution in order to find a legitimate reason for fair use.


The acurate transmission probabilities in the molecular flow region for conical tubes of various lengths and angles were calculated by solving Clausingintegral equation (IE). An approxmate equationtothe results based on the expression proposed by Fustoss has been derived. The agreementis within 5% of the exact valuesin the whole region.


We report on the development of a new software package for image reconstruction in threedimensional Electrical Impedance Tomography (EIT). Designed for large-scale computations, the software includes mesh generation utilities, a simulator of the quasi-static electrical potential fields based on finite elements and regularized inversion algorithms. We describe in brief some of its main functions and characteristics to demonstrate its utility and efficiency in handling high dimensional geophysical models.


Abstract : Thermal elastohydrodynamic (EHD) lubrication of rolling/sliding line contacts is investigated to develop an interactive computer program for prediction of lubrication system performance. The user inputs lubricant and mechanical system physical properties as well as operating conditions of load and speed for calculation of contact zone pressure, temperature, traction, and stresses. This program is one of the first to include thermal effects in calculations and, therefore, can more accurately assess the critical tribological performance parameters at high load and speed conditions than previous prediction models. The program is written in the FORTRAN language and utilizes a UNIX operating system for high quality graphic output allowing easy visualization of results.


In my paper on the "Unsymmetrical Distribution of Terrestrial Magnetism," it was shown that by heating small surfaces of the thin sheet iron entirely covering the ocean areas of the mapped globe strong magnetic polarity was induced at the heated parts, just as when the magnetic continuity of the iron was interrupted by cutting through the same parts of the iron in an equatorial direction.


is the screening function. The square-root in the screening length was inadvertently omitted in the original paper. The knot point r4 HFe in Table VIII in the original paper should be at 3.0 Å. Finally, the parameters for the interpolating polynomial should be revised as indicated in Table I; all other parameters remain unaltered.1 Please note that these corrections only alter the Fe–H two-body interaction for distances below 1.2 Å, a range that is never actually sampled in any of the atomic configurations used in the fitting procedure. The Fe–H two-body interaction in all our configurations is completely described by the cubic splines—the interpolating polynomial and the Biersack-Ziegler form merely provide continuity below 1.2 Å. Hence, our results and conclusions remain unaltered.


The purpose of this research project is to explore the perception of open access journals among physics researchers. The paper presents the findings of questionnaire survey and interviews to examine perceived advantages and disadvantages of open access journals. Even though Bangalore has a large number of physics researchers spread across various research institutions, this study is limited to physics researchers of Indian Institute of Science and Raman Research Institute, Bangalore, India. We believe that results of this survey will help both libraries and publishers in understanding awareness about open access journals. A structured questionnaire was distributed to 260 physics researchers; 200 responses were obtained. The analysis revealed that researchers give priority to factors like quality of peer review and impact factor before selecting an open access journal for publishing. Further, this study also showed that 80 per cent of researchers agree that there is fundamental benefit in open access publishing.


This chapter traces the response to inequality and financial collapse in the United Kingdom, with the anti-system Right represented by the Brexit campaign, and the Left by Jeremy Corbyn's takeover of the Labour Party. Like Trump's election in the United States, which it preceded by less than six months, the Brexit vote was an anti-system vote, a vote of rejection of the existing political establishment and the economic policies it had implemented since the 1980s. Just as Trump's victory mobilized entrenched racial divides in the United States, Brexit reflected a long-standing skepticism about European integration in British society. The chapter then argues that Brexit formed part of a wider anti-system revolt in Britain, which replaced the centrist politics of the 1990s and 2000s with a deeply polarized politics pitting half the country against the other.


Abstract DATA are available which indicate that the poultry industry suffers considerably each year through morbidity caused by internal parasites (Todd, 1948; Reid and Carmon, 1958; Reid, 1958; Todd and Hansen, 1951). Intestinal parasites can result in higher mortality and decreased resistance to other diseases. Peterson and Kerr (1950) showed that intestinal roundworms contribute to higher mortality in chicks exposed to Newcastle disease; and Riedel (1950) reported that chicks infected with large roundworms have less resistance to cecal coccidiosis than worm-free chicks. Intestinal worms compete with their host for nutrients and can cause serious trouble as indicated by the findings of Pande and Krishnamurty (1959). A study of farm records pertaining to post mortem examinations of birds and the schedule of rations fed in India provided a strong indication of an inter-relationship between hypovitaminosis A and infestation with large roundworms. This inter-relationship manifested itself by a vicious cycle of clinico-pathological events, …


Background: The concept of a clean label is difficult to define, even in common language, as the interpretation of what a "clean" food is differs from one person to another and from one organisation to another. The lack of a unique definition and regulations of what the term "clean" means, along with the growing consumer demand for more "natural" and healthier foods, is posing new challenges for manufacturers and ingredient producers. The meat industry, in particular, has been affected by this new movement owing to negative attitudes and feelings consumers associate with consuming processed meat products. Scope and approach: The review scope is to describe attributes and associations around the "clean" label term by analysing the most recent ingredients, additives and processing methods currently available for meat manufacturers. Their application in meat, plant-based alternatives and hybrid meat/plant products, current limitations and challenges presented in consumer perception, safety and potential impacts on product quality are also presented. Key findings and conclusions: The availability of a growing number of "clean" label ingredients provides a new suite of approaches that are available for application by meat processors to help overcome some of the negative connotations associated with processed meat products and also support plant-based meat alternatives and hybrids.


A new species, Polymnia cossatotensis, is described from the Cossatot Mountains, a range of mountains in the Ouachita Division of the Interior Highlands. It was found growing abundantly on and among cherty novaculite talus. Polymnia cossatotensis is most closely related to P laevigata and P. canadensis but is easily distinguished by its annual habit, cordate cauline leaves, fewer rays, and larger achenes. In early October of 1988, during fieldwork along the Little Missouri River in west-central Arkansas, an unusual composite was noticed growing abundantly in an open area of cherty novaculite talus. The plants, approaching two meters in height and exuding a pungent odor, were often directly attached to bare rock surfaces by both adventitious and thickened secondary roots. Also present in the talus were Ambrosia trifida , Hybanthus concolor ; Phytolacca americana, Rhamnus carolinianus , Bumelia lanuginosa , Asimina triloba , and several common woody vines, Toxicodendron radicans, Vit is rot undif olia , Campsis radicans, and Parthenocissus quinquefolia . The overstory on the terrace below the talus slope consisted primarily of Vagus grandifolia, Carpinus caroliniana, Magnolia tripetala , and Ilex opaca while Quercus muhlenbergii , Liquidambar styraciflua, Ostrya virginiana , and Ceitis laevigata occurred on the adjacent drier slopes. The new Polymnia is named after the Cossatot Mountains, a range of mountains in the south-central section of the Ouachita Division of the Interior Highlands.


Oregon State University and Merix Corp. (Forest Grove, OR) have initiated a cooperative University-Industry program for hands-on education of engineering students. This interdisciplinary program spans the Departments of Chemical Engineering (ChE), Electrical and Computer Engineering (ECE), Industrial and Manufacturing Engineering (IME) and Mechanical Engineering (ME) and focuses on the design and manufacture of a printed circuit board using actual PCB manufacturing equipment in a new PCB laboratory housed at OSU. Curriculum development will include courses to develop "core competency" in each major discipline, and a capstone PCB Design and Manufacturing laboratory course which will focus on interdisciplinary group activities aimed towards a common goal -the production of a printed circuit board. Educational programs will be offered at the engineering technology (local community colleges), advanced undergraduate and graduate levels (OSU). The laboratory development and operation is a cooperative activity between OSU and local industry to promote education and research in the electronics industry. INTRODUCTION The 50th Anniversary issue of Chemical Engineering Progress (January, 1997) provided many articles related to chemical engineering "then and now". In one of those articles David Koch looked at the role education will play in shaping the future of chemical engineering (1). He mentioned the beginnings of three "trends" which he thought would be very important. The first was professional education , which he described as ".. exposing students to actual industrial practice provides the best educational laboratory for learning design, problem-solving, and teamwork, among other things." The second was interdisciplinary, which he suggested was a natural result of the broadening of the field of chemical engineering to include new growth industries. The third was the electronic classroom, where very fast and cheap computers would make the virtual chemical engineering laboratory a possibility. All of these concepts are addressed with the curriculum development project described in this paper. There are a number of excellent examples where programs have been developed to address a change in undergraduate engineering education to emphasize the practical experience and interdisciplinary teamwork concepts suggested by industry (2 7). The unique aspects of the current project are that the curriculum and laboratory development focus on two distinct philosophies: P ge 275.1 • Providing the students an interdisciplinary experience in which the unique talents of the individuals (their "domain competencies") are used to solve problems in a team setting. For this mode of operation to be effective, each team member must have a firm grasp of the overall process and understand the capabilities of their team members. That is, everyone must have the "big picture" so they can work toward a common goal, but it is not necessary for them to comprehend how to address each individual problem. • The common goal in this case is a product -the printed circuit board. The groups must realize that their success or failure lies in their ability to deliver a product in a timely manner and to specifications, and that they are a key link in the process. If they fail, the operation can proceed no further. The traditional university environment is "departmentalized" and provides for little crossdiscipline team experience for graduates preparing to enter industry -which is team dominated. Additionally, university laboratory experiences tend to be oriented toward unit operations rather than an integrated process . An example of a "unit operations experience" is an electrical engineering course on the principles of circuit board design, with a supporting laboratory where computer-aided design tools are used to design circuit boards. The student typically never interacts with those who manufacture and test the circuit board designed. In an "i tegrated experience" students from the electrical, chemical, industrial and manufacturing engineering departments would all complete unit operations oriented courses and laboratories where their "domain competency" is developed in the same manner as in the electrical engineering example above. Subsequently, interdisciplinary teams of students would be formed in which each student would bring their "domain competency" to the team. Each team would then participate in an integrated process that encompasses design and manufacture of a product (in this example a printed circuit board). This experience mimics industrial practice. GOALS AND OBJECTIVES The goal of this project is to establish an integrated printed circuit board (PCB) design and manufacturing facility, and develop curricular material to provide interdisciplinary student teams a completely integrated PCB design and manufacturing experience. The following objectives have or will be addressed: Objective 1: Complete the design of the PCB laboratory facility with the advice and guidance of the Electronics Manufacturers Association (EMA) of Oregon. Objective 2: Procure and install the equipment and software required for startup of the facility. The majority of the equipment will be provided by EMA members. Objective 3: Develop and integrate domain specific courses in Electrical and Computer Engineering (ECE), Industrial and Manufacturing Engineering (IME), and Chemical Engineering (ChE) that prepare students for an interdisciplinary team experience in PCB design and manufacturing. Each of these three courses will focus on engineering principles associated with PCB design and manufacture and the use of software tools and laboratory equipment available to reinforce these principles. P ge 275.2 Objective 4: Develop and integrate into the curriculum a c pstone laboratory project course that will provide interdisciplinary student teams with the experience of design and manufacture of a functional printed circuit board. Objective 5: Develop curricular materials (e.g.., multimedia computer models; lecture materials and problems, etc.) that use printed circuit board design and manufacturing as a vehicle to illustrate engineering principles such as mass and energy balances, fluid mechanics, statistical process control, etc. These materials will be used in the program at OSU and will be made available to the educational community, in part through the development of an OSU PCB Laboratory Home Page on the WWWeb. Objective 6: Develop the capability to provide small lots of custom printed circuit boards at cost for use by other educational institutions that have neither the facility to produce them or the funds to commercially procure them. Objective 7: Develop a relationship and training program with the local community colleges, to provide training in the maintenance and operation of PCB manufacturing equipment. This is in direct response to the needs of Oregon industries EDUCATIONAL IMPACT The educational impact of this project should be far reaching because it will: 1) improve the undergraduate engineering curriculum at Oregon State University, 2) provide a mechanism for interaction with the local community college, 3) provide a mechanism for interaction with other educational institutions, 4) provide for continued long term interaction with industry, and 5) will provide a model for laboratory and curricular reform. 1) Improvements to the undergraduate engineering curricula at OSU will be provided through establishment of an integrated printed circuit board design and manufacturing laboratory spanning the departments of ECE, IME, and ChE, and development of three new lecture / laboratory courses, and a new interdisciplinary capstone course. The proposed course titles are: • ECE Principles of printed circuit board design and manufacturing • IME Principles of printed circuit board design and manufacturing • ChE Principles of printed circuit board design and manufacturing • Printed Circuit Board Design and Manufacturing Laboratory In the first three lecture/laboratory courses domain competencies will be developed and engineering principles will be demonstrated with PCB manufacturing equipment and software tools. As a result of this course the students will have produced a functional product. There is no course or sequence of courses at OSU that provides this experience. The capstone laboratory course will provide new exposures and experiences in areas not typically addressed in specific domains. For example, statistical process control (SPC) and design of experiments (DOE) will be addressed in the capstone course but are not addressed in either the chemical or electrical engineering curricula. P ge 275.3 2) The local community college (Linn-Benton Community College LBCC)will be able to provide operator and maintenance training for PCB manufacturing equipment with the facilities established through this project. In addition to developing programs in the maintenance and operator training areas, LBCC will also be able to provide assistance to OSU in the maintenance of the facilities through their student projects. 3) This project will benefit other educational institutions in several ways: • provide multi-media modules that demonstrate basic engineering principles such as mass balances, through the vehicle of PCB manufacturing facilities. • provide a remote manufacturing facility for small lots of PCBs at cost of materials. • enhance the educational experience of students by dealing with a remote manufacturing facility through electronic media. • provide a model for development of interdisciplinary student team activities that reflect a real design and manufacturing process 4) This project has grown from industry and university interaction. The formation of the PCB Design and Manufacturing Advisory Board, and the significant commitments of equipment and support from the industry ensure continued long term industry interaction. 5) This unique program that addresses a critical ar


Today's business leaders face a global environment that is marked by increasingly volatile, uncertain, complex, and ambiguous (VUCA) conditions. Design thinking offers a proven way to navigate in a VUCA environment. I used this approach while serving as a military officer in Iraq and Afghanistan. This chapter focuses on what I learned from applying design thinking to our operations as well as on insights from businesses that have also successfully integrated design thinking. I use the framework "inspire, ideate, and implement" to describe how I utilized design thinking. I finish the chapter with key factors for successfully employing a design methodology to VUCA problems.

Design thinking empowers organizations to tackle successfully VUCA challenges. Inspiration allows designers to frame relevant problems that clients care about. With the pressing challenge in hand, designers immerse themselves in the context of a problem to empathize with a customer's concerns. They synthesize input from a variety of diverse sources, and meet experts who can give meaning to their collected data. With this comprehensive picture in hand, design teams brainstorm new possibilities as they move into ideation. Taking their ideas out for a test run, they iterate the most promising ways to move into action. They conduct pilot projects, adapt to what works best, and share their learning from the process. Leaders with a design mindset, aligned with a collaborative organizational culture and congruent support systems, can build an innovative enterprise that is primed to thrive in a VUCA world.


This paper reviews the methods to identify unauthorized cryptocurrency mining customers in distribution networks. Hence, various methods and models were compared. Also, the research conducted in the field of cryptocurrencies was evaluated in the four categories of energy, pollution, theft, and mining.


Facial fi llers, injectable therapeutic materials for soft tissue augmentation, are ideal for restoring facial volume and contour. With recognition of its value, as well as the ease of offi ce procedures, fi ller injection has become one of the most commonly performed cosmetic procedures. Yet, fi llers are implants and essentially foreign bodies that can trigger an infl ammatory response in individuals. In addition, fi ller injection is a blind procedure in which the physician is unable to see exactly where the material is placed. With these characteristics, injectable fi llers have the potential for a myriad of complications. Moreover, in East Asian countries, injection of illegal materials by unlicensed practitioners are widespread with an increased risk of fi ller complications. We herein present a case of fi ller migration to the eyelid, a rare complication following illegal fi ller injection. To our knowledge, this complication has not been reported previously in the dermatologic literature. A 74-year-old female presented to the dermatologic outpatient clinic with a history of gradually enlarging swelling on the left upper eyelid. Clinical examination disclosed a yellowish, fi rm and nontender mass on the left upper eyelid (Figure 1A and B). The mass was not associated with decreased visual acuity, ocular motility limitation, or proptosis. The patient stated that she received fi ller injection on the forehead by an illegal practitioner 3 years ago and the lesion was said to develop a month afterwards. Although our patient recalled the injected material as a liquid agent, she was not able to identify the exact nature of the substance. She denied of being injected in the periorbital region and also of a trauma history. A skin biopsy was performed from the eyelid mass. Histopathologically, there was diffuse granulomatous infl ammation throughout the dermis. Under high magnifi cation, numerous lipid vacuoles were seen surrounded by epithelioid histiocytes and multi-nucleated giant cells. The overlying epidermis was intact and unremarkable (Figure 2A and B). Although we were not able to identify the exact fi ller substance, the clinical and histological fi ndings were in keeping with the diagnosis of a lipogranuloma from fi ller migration. The patient was asked to undergo treatment, but is currently lost for follow-up. Clinically detectable granuloma formation following facial fi ller injections is a well-known complication, where complication rates vary from 0.01% to 0.1% (1). This is not surprising, as all skin-implanted exogenous substances can trigger an infl ammatory response in individuals. Notably, oily substances such as silicone and paraffi n have commonly been reported to produce a foreign body granulomatous reaction known as " sclerosing lipogranuloma " (2). The pathogenesis of eyelid mass formation after fi ller injection to the forehead can be explained by the consideration of the galea as the superfi cial musculo-aponeurotic system (1). The layers of the forehead consist of the skin, subcutaneous tissue, frontalis muscle, galea aponeurotica, loose areaolar tissue, and periosteum. The subcutaneous fat layer in the forehead is connected with the brow fat pad, while the galea is connected with the posterior orbicularis fascia. The galea is a broad sheet, and the tissue plane formed by the galea and the posterior orbicularis fascia can function as a migration pathway of the injected material from the forehead to the upper eyelid. Injected fi ller substances may migrate through the galea aponeurosis and the retroorbicularis fascia by gravity, facial muscle movement and postoperative massage of the injection sites for better distribution of the injected material. Moreover,


With the continuous development of analytical instrumentation,atomic absorption spectrometry for single element analysis is widely used,and multi-element analysis studies have achieved some results.From the development of the spectrometer part,the paper discusses the impact and its application of the atomic absorption spectrum light source for multi-element.


SET‐CAN associated with the t(9;9) in acute undifferentiated leukemia encodes almost the entire sequence of SET and the C‐terminal two‐third portion of CAN, including the FG repeat region. To clarify a role(s) of SET‐CAN in leukemogenesis, we developed transgenic mice expressing SET‐CAN under the control of the Gata1 gene hematopoietic regulatory domain that is active in distinct sets of hematopoietic cells. SET‐CAN transgenic mice showed anemia, thrombocytopenia, and splenomegaly. A significant number of transgenic mice started dying after 6 months post‐birth, being in good agreement with the fact that red blood cells and platelets decreased. We found that a significant number of c‐kit+ myeloid cells appeared in peripheral blood in transgenic mice. Characterization of the bone marrow cells of transgenic mice indicated impairment in hematopoietic differentiation of erythroid, megakaryocytic, and B cell lineages by SET‐CAN. Transgenic mice, in particular, exhibited a high population of the c‐kit+Sca‐1+Lin− fraction in bone marrow cells compared with that of the control littermates. Our results demonstrate that SET‐CAN blocks the hematopoietic differentiation program—one of the characteristics of acute myeloid leukemia. J. Cell. Physiol. 214: 322–333, 2008. © 2007 Wiley‐Liss, Inc.


Yurevich R. A., Taran D. F., Frolova O. E. Assessment of the suitability of the rivers of the river basin. Vilia for the reproduction of salmon fish and ways to restore their population