The potential implications for development of professionally defined "standards of care" treatment procedures for mental health counseling are presented. The role of xpert witnesses in malpractice cases is examined as one source from which the standards are currently derived. The influence of managed care on the current clinical practices is noted. Finally, the importance of using outcome research as the basis for developing a "best practices" concept of standards of care is discussed. The authors note difficulties and challenges involved in making a commitment to what could be the next major impetus to the mental health movement.


Simulations of the nuclear magnetic shielding within the generalized gradient approximation (GGA) for α-pinene and taxol were carried out to assess the performance of the method for bigger molecules. The localized orbital/local origin gauge (LORG) formalism and the modified "0.05" Becke's three-parameter exchange functional and the gradient-corrected functional of Lee, Yang, and Paar (B3LYP) proposed recently by Wilson and others was used. A modest dependence of the results on the basis set size was observed. For the current implementation, the uncoupled calculations were up to 47 times faster than the usual coupled-perturbed (CP)–gauge-invariant atomic orbital (GIAO) method and provided similar accuracy. Reproducing both the absolute as the relative chemical shifts the GGA/LORG procedure can thus be used as a faster alternative to the coupled techniques. © 2002 Wiley Periodicals, Inc. Int J Quantum Chem, 2003


Trust is crucial for successful social interactions and personal well-being. Among the many mechanisms potentially favoring the evolution of trust, spillovers of social institutions on subsequent behavior have received little attention within evolutionary psychology. Although a plethora of research has investigated pro-social spillovers in economic experiments, research has thus far largely overlooked the impact of spillovers on person perception. Additionally, given that most studies on such spillovers use one-off measurement of the subsequent behavior, the stability of pro-social spillovers over time has not been investigated so far. In a three-stage laboratory experiment (n = 208), we provide evidence that pro-social spillovers occur even when perceptual cues provide an additional source of information to base decisions on. In Stage 1, participants played a series of trust games against unknown, videotaped targets to assess their baseline trust behavior against strangers, taking into account their trust perception. Subsequently, we randomly exposed them to a repeated prisoner's dilemma in which cooperation is either favored ("C-culture") or discouraged ("D-culture"). In the final stage – another series of 30 trust decisions against different targets – participants from the "C-culture" initially respond with higher levels of trust. This spillover effect, however, is short-lived and behavior converges back to the pre-intervention levels. Thus, our findings confirm pro-social spillovers even when participants behavior may also be influenced by perceptual cues but raise the question about their temporal stability. We complemented the experiment with an independent survey (n = 132) on the trustworthiness of the targets. Results show that these perception affects quickly gain predictive quality, suggesting the intervention effect only temporarily crowds out the trustworthiness perception as a key driver of trust behavior.


ABSTRACT Gibberellins (GAs) are a family of plant hormones that are important to multiple aspects of plant growth and development, especially stem elongation. A PSRK2 was obtained through screening and identifying RLK dominant negative mutants. Phenotype of the loss-of-function mutants, psrk2-DN and psrk2-RNAi, showed that PSRK2 could influence the length of the uppermost and fourth internodes, indicating that PSRK2 might regulate cell division in the intercalary meristems and/or cell elongation in the internodes. Moreover, the expression pattern showed that PSRK2 was strongly expressed in the joined-nodes after the start-up of reproductive growth, but undetectable in leaves. PSRK2 expression was also found to be induced by GA3, and PSRK2 was involved in GA signaling in cereal aleurone cells, and PSRK2 influence the relative length of the second leaf sheaths in seedling stage. These results indicate PSRK2 is a component of GA signaling pathway that controls stem elongation by negatively regulating GA responses. Abbreviations: Os: Oryza sativa; At: Arabidopsis thaliana; RNAi: RNA interfere; DN: Dominate Negative; SMART: Simple Modular Architecture Research Tool; Uni : Uniconazol; PSRK2: Plant Stature Related receptor-like Kinase 2; RLK: Receptor-like Kinase; GA: Gibberellin; IAA: indole-3-acetic acid; BL: Brassinosteroid Graphical Abstract PSRK2 could influence the length of internodes in rice, indicating that PSRK2 might regulate cell division and/or cell elongation in GA signaling pathway


Recent advances in wireless sensor network's technology have developed using this technology in various fields. For the importance and intense application of these networks, many efforts and researchers have been done to confront challenges. In this paper, to conquer one of the most important challenges of these networks, that is the limitation in energy resources, an adaptive scheduling algorithm based in Potts model was applied. According to this model, for every element of a system, q different states are considered. Each element converts its state to a new state or remains in that state due to its current state and its adjacent neighbours and with the effect of environment. In this project, this model was used in wireless sensor networks such that each sensor node is considered as an element of sensor network system and three active, inactive and standby states are defined for that node, which it selects one of these three states according to its current state and neighbours and environment effect and adapts its activity with the environment in a way that the least energy to be consumed. By comparing this algorithm and similar algorithm (with two states), it is observed that in identical conditions, Potts model with three states represents better results and more lifetimes for network.


4579 Background: Patients (pts) with mUC have an estimated 5-year overall survival (OS) rate of 14%. Trop-2 is a transmembrane glycoprotein with elevated expression in many cancers, including UC. SG is a Trop-2–directed antibody-drug conjugate with accelerated FDA approval for pts with LA unresectable or mUC who previously received platinum (PT) and a checkpoint inhibitor (CPI). SG has demonstrated activity in 3 phase 2 TROPHY-U-01 mUC cohorts: Cohort 1 (C1), 28% objective response rate (ORR); Cohort 2 (C2), 32% ORR; and Cohort 3 (C3), 41% ORR. Here, we assess efficacy outcomes in C1-3 by Trop-2 archival tumor expression. Methods: Pts (≥18 years) with previously treated (PT [C3], CPI [C2], or both [C1]) LA or mUC received SG (10 mg/kg IV) on D1 and D8 of 21-D cycles; C3 pts also received pembrolizumab (200 mg) on D1 of 21-D cycles. The primary endpoint was ORR by independent review. Archival tumor samples collected at enrollment were assessed for Trop-2 protein expression using SP295 anti–Trop-2 antibody by IHC with assessment by histological scores (H-scores; scale, 0-300) and % of membrane-positive tumor cells (Roche Tissue Services). Trop-2 association with clinical endpoints was evaluated using unstratified Cox proportional hazards models for survival data and logistic regression for ORR. Results: At data cutoff, 192 pts were enrolled in C1-3; 144 pts (75%) had samples evaluable for Trop-2 prevalence and 139 pts (72%) were evaluable for efficacy analysis by Trop-2 expression (5 pts not assigned to any cohort were excluded). Baseline characteristics for pts with evaluable samples were consistent with the overall population. Median (IQR) Trop-2 H-score and % of membrane-positive tumor cells for evaluable pt samples were 215 (180-247) and 92% (75-98), respectively; these readouts were highly correlated (ρ=0.82, P<0.001). ORRs for C1 samples with below (n=42) and above (n=45) median Trop-2 H-scores were 24% and 29% ( P=0.59), respectively; median progression-free survival (PFS) was 3.4 and 6.7 months (HR=0.765, P=0.262), respectively; and median OS was 9.9 and 10.9 months (HR=0.978, P=0.927), respectively. Median PFS for C1 samples with below and above median Trop-2 membrane positivity were 3.9 and 6.2 months (HR=0.835, P=0.443), respectively. Analyses of efficacy endpoints for C2 and C3 pt samples by Trop-2 expression were consistent with C1 results. Conclusions: In this analysis of archival tumor samples from pts with pretreated LA or mUC, Trop-2 protein was highly expressed across cohorts, supporting prior Trop-2 expression analyses in UC. Similar outcomes were observed between C1 pts with samples that were below and above median Trop-2 H-score with most pronounced numerical differences observed for PFS. These results suggest that SG activity may be independent of Trop-2 expression in UC, but additional studies are needed to confirm these results. Clinical trial information: NCT03547973 .


Supporting multicast in a wired shred medium based LAN such as the ethernet is thought to be natural. Since all unicast, multicast and broadcast frames can be processed for the same cost by the same basic routing mechanism based on broadcast and filtering. However, because of power conservation techniques commonly used in the design of wireless systems for the limited battery life of mobile terminals, the connectivity of a terminal in power save mode is restricted. That is, all connectivity property that every terminal in the same shared medium LAN gets to be received by a single broadcasted frame would not be applicable, which makes it difficult to apply broadcast and filtering mechanism naively. The IEEE 802.11 standard defines a mechanism enforcing all connectivity property at certain time intervals determined by a special interval value called DTIM (Delivery TIM) [1]. But DTIM mechanism consumes additional power even if there is no multicast traffic, and its service quality may be poor according to the DTIM value selected [6]. While there are a lot of studies for the power saving routing/multicast in the IEEE 802.11 based ad-hoc network [2],[3], we can hardly find a study for the IEEE 802.11 based infrastructure network. In this paper, we propose a new mechanism that does not require all connectivity property by scheduling a multicast frame with n-ary sub-multicasts. As it consumes no additional power for multicast, it is more power efficient. But it requires more bandwidth and may increase delay. However, we assert that it could maintain bandwidth and delay increase under permissible level through a carefully selected cost function. Our performance study based on computer simulation support 846


The purpose of this study was to investigate the perception about AI assistants and the differences between two groups, workers(secretaries) and supervisors(bosses), using the Q-methodology which has an advantage in understanding the types of subjective perceptions. Through literature reviews and interviews, 34 Q-samples were extracted, and then Q-sorting was conducted by P-samples(20 workers and 15 supervisors). As a result of Q-sorting, the types and characteristics of AI assistants perceived by each P-sample were explained. The perception of the workers divided into five distinct types, and the perception of the supervisors was divided into three distinct types. The most crucial factors in distinguishing between workers and supervisors' perceptions depend on whether they are capable of performing certain tasks and whether they can replace existing secretarial jobs. This study, as the primary research on AI assistants, can help to redefine the work that can be replaced by AI and the work that only people can do, and thus to establish education, recruitment, and training plans.


This brief article discusses the role of chemicals in winter maintenance. Chemicals are used to depress the freezing point of winter precipitation. Their anti-icing effect minimizes the amount of chemicals required and increases the safety of the road. If the anti-icing goal is not achieved, traditional deicing techniques can be applied. Deicing chemicals bore through the snow and ice to the pavement, where the liquid chemical works to destroy the bond between the snow and ice and the roadway surface.


FIELD: physics; geophysics. SUBSTANCE: invention relates to geophysics and can be used to process seismic data. Disclosed is a method for speeding up iterative inversion of seismic data to obtain a subsurface model using local cost function optimisation. The frequency spectrum of the updated model at each iteration is controlled to match a known or estimated frequency spectrum for the subsurface region, preferably the average amplitude spectrum of the subsurface P-impedance. The controlling is done by applying a spectral-shaping filter to the source wavelet and to the data or by applying the filter, which may vary with time, to the gradient of the cost function. EFFECT: high accuracy of obtained data. 23 cl, 15 dwg


A case study has been made to explore whether the teacher's role in data-driven learning(DDL)can be minimized.The outcome shows that the teacher's role in offering an explicit instruction may be indispensable and even central to the acquisi tion of English articles.


A wafer baking plate is set in wafer ovens, and wafer dough is baked to produce wafer sheets. Since wafer dough contains more than 50% water and is baked in a closed environment, it creates high pressure over time. This pressure puts considerable strain on the wafer baking plate and locking mechanisms and adversely affects the locking mechanism. In this case, it is necessary to calculate the stresses and displacements on the parts by modelling the loads and the boundary conditions specific to the problem for various plate locking mechanisms. This study used the finite element method to calculate and compare the stress and displacement values on two different locking mechanisms of a wafer baking plate. As a result of the analysis, the Von Mises stress value of the butterfly lock mechanism was 34.5% higher than the hook lock mechanism. The displacement value of the hook lock mechanism is 9.5% lower than the butterfly lock mechanism. Since the total contact area of the butterfly lock mechanism is shallow and the Von Mises stress value is higher than the other mechanism, it is predicted that the wear will be higher in continuous operation.


[ ]this pandemic has broadened the locus of safety compliance to include organizational outsiders Physical proximity is imperative for promoting work safety behaviors Work safety behaviors are construed and measured as behaviors enacted in the physical boundaries of the workplace (e g , Griffin & Neal, 2000) [ ]previous research (e g , Luria & Morag, 2012) has shown that physical proximity of supervisors to employees improves employee safety behaviors Workers who are working from home are still vulnerable to work-related hazards Besides COVID-19 being a large threat to employee safety, there are other physical and psychosocial safety risks of working from home


A conversation is a joint activity between interlocutors, whose contributions are tied in with their partners' contributions (Clark, 1996). An isolated speaker 1 producing a monologue has to work on her own model of what to say, together with assumptions about the presumed audience. But an interlocutor's contribution in a dialogue is dependent on prior contributions by other interlocutors, for instance in response to a question or a request for more information. Importantly, this dependency relates not only to the content


It has been a big challenge to effectively collect coarse and fine droplets from the air by compact and light equipment. In this report, a novel strategy of collecting coarse and fine droplets from the air, which employs an ultrasonic field in the air gap between a flat radiation surface and parallel reflector, is demonstrated. Coarse and fine droplets (PM2.5-10 and PM2.5) can be effectively collected onto the reflector's surface when the air gap thickness is proper. The radiation surface works in a flexural vibration mode at 56.9 kHz, and the collected droplets may form concentric rings and irregular shape on the reflector's surface. Analyses show that both of the acoustic streaming and acoustic radiation force are responsible for the collection.


A new species of the genus Manulea Wallengren, 1863, M. hokopo sp. n. is described from the island of Taiwan. The new species is similar to M. costipuncta Leech, 1890 widely distributed in mainland China, Hainan Island and North Vietnam. Adults, male and female genitalia of both species are illustrated.


The alarming spread of alcoholism is noted and its aetiology is examined in the light of its many causes and influencing factors. Steps to stem the tide are discussed, along with the methods to be adopted and the persons by whom they should be put into effect. Drinkers are classed as large and small alcoholics and the incidene of alcoholism in 3009 male and female patients is examined in the light of the type of drink involved, occupation, age and reason for admission to hospital. Attention is drawn to the high number of male alcoholics. Screening for alcoholism in hospital is recommended as a means of preventing the syndrome.


In every organism, the expression of genes is regulated in response to the changes in the surrounding environment. The study of epigenetics in plants is essential in view of the improvement of agricultural productivity. Epigenetic modifications can enhance crops' yield and stress tolerance without making any alteration within their genomic sequences. The routes of epigenetic modifications include processes such as methylation of DNA, modifications of histone proteins, chromatin remodeling, and non-coding RNA-mediated regulation of genes. Genome-wide epigenetic profiles, coined as the epigenome, of several plants have been identified in recent years. In the scope of this review, we are going to discuss progress made in the field of plant epigenomics under the limelight of stress tolerance, especially saline conditions.


Development of stretchable sensors has recently attracted significant attention in the field of robotics. It is promising to design an "invisible" and "feelingless" sensor with stretchable capability. This paper presents a new method to fabricate a wearable stretchable sensor, which is relatively simpler than the existing manufacturing methods. The developed sensor has a sandwich structure consisting of two elastomer layers and one soft electrode layer in-between. By applying the new manufacturing method, the whole thickness of the stretchable sensor can be controlled to be less than 0.5mm. Carbon grease is employed as the resistance electrode and copper-tin fabric works as the wires. Due to the soft and stretchable nature, the developed sensor is effective in detecting motions of body joints. For verification, a stretchable skin-like glove with multiple sensors is fabricated as a palm-like measurement system to capture the motions of five fingers simultaneously. Experiments are performed to validate the performance of a single sensor and the integrated soft glove.


This study presents the results of qualitative assessment of environmental impacts on the forest stage of implementation, considering the activities of cleaning and preparation of the land, through the application of matrix methods of identification and interaction impacts, descriptive list (checklist) and the combination/ weight attributes. This assessment was based on the identification and qualitative characterization of environmental impacts, whose methodologies allowed the fast and hierarchical view of the impacts. Through the array was revealed a possible relationship of 348 impacts (total capacity of the matrix), and of these 304 (87.6%) were identified, which impacts 209 (60.05%) relapsed on the biophysical environment and 95 (27, 31%) on the socioeconomic environment. Among the 209 impacts on the biophysical environment, all showed a 1 Recebido em 28.11.2011 aceito para publicação em 06.08.2013. 2 Programa de Pós-Graduação em Ciências Agrárias na Universidade Federal Rural da Amazônia, UFRA, Brasil. E-mail: <email@example.com>. 3 Universidade Federal Rural da Amazônia, UFRA, Brasil. E-mail: <firstname.lastname@example.com>, <email@example.com>, <email@example.com> e <firstname.lastname@example.com>. 4 Departamento de Engenharia Florestal da Universidade Federal de Viçosa, UFV, Brasil.E-mail: <firstname.lastname@example.com>.


Based on a Hamiltonian that incorporates the elastic coupling between a tracer and active particles, we derive a generalized Langevin model for the non-equilibrium mechanical response of active viscoelastic biomatter. Our model accounts for the power-law viscoelastic response of the embedding polymeric network as well as for the non-equilibrium energy transfer between active and tracer particles. Our analytical expressions for the frequency-dependent response function and the positional autocorrelation function agree nicely with experimental data for red blood cells and actomyosin networks with and without ATP. The fitted effective active-particle temperature, elastic constants and effective friction coefficients of our model allow straightforward physical interpretation.


Constructive algebraic geometry methods were used to discuss multivariate interpolation problems for which the interpolation nodes are taken from one algebraic manifold and the related theories and algorithms for constructing minimal degree interpolation basis were presented.An estimation for the degree of interpolation polynomial was also presented.


After participating at the international conference entitled Precarity or Self-Management (Prekarnost ali samoupravljanje) in autumn of 2020, Andrej Mirčev suggested we continue our collaboration by putting together a special thematic edition of Maska on the topic of 'police'
 as a political and performative issue, which at the time seemed to us a relevant and interesting field for critical analysis. But back then we had no idea, nor were in any way able to anticipate, how seriously or immediately the issue of violence against physical bodies will feature in our
 daily lives, especially in the later phases of the corona pandemic and the expansion of actual violence after February 2022.


This paper proposes a new spatiotemporal equalization method, which utilizes an adaptive antenna array and a decision feedback equalizer (DFE) simultaneously. For e ective spatiotemporal equalization, how to assign the role to spatial equalization part and temporal equalization part is really important. One of the answers which we have given is `incoming signals with larger time delays should be cancelled at the spatial equalization part.' The weights of both adaptive antenna array elements and taps of DFE are calculated only using the estimated channel impulse response, therefore, it requires no information on direction of arrival (DoA). We show the performance of the proposed system in multipath fading channels often encountered in indoor wireless environments, and discuss the attainable bit error rate (BER) and the computational complexity in comparison with other equalization methods, such as spatial equalization and temporal equalization.


This study empirically examine the influence of professional commitment, ethical judgements, and the components of planned behavior to the intention of internal whistleblowing. The data in this study are primary data which obtained by distributing questionnaires directly to the respondents, undergraduated accounting students at the University of Muhammadiyah. The sampling technique using purposive sampling method. Hypothesis testing is done by multiple regression analysis. The results showed that the only variable subjective norms has positive effects on internal whistleblowing intentions, while the other variables are professional commitment, ethical judgements, attitudes, and perceived behavior control is not having an effect to the intention of internal whistleblowing. Results of regression estimates indicate the predictive ability of the model by 39.2% while the remaining 60.8% is influenced by other factors outside the research model.


A model of optimization of anti-slipping device holder conicity, based on the criterion of maximal efficiency coefficient of wheeled aggregate chassis is presented. Optimal conicity values for concrete operational conditions of the МТЗ-80 + КПК-2-01 potato harvesting aggregate were obtained.


This paper aims to research the dispersion impact on performance of the fiber transmission system.Firstly,the simulation model of the transmission system is presented on the basis of analyzing all the parts of the system.Secondly, a simulation model is proposed which pays much attention to the fiber dispersion.The influence of the fiber dispersion in several conditions on the basis of the simulation model is researched.At last,it is approved that the result of the simula- tion is the same to the theory analyzing.At the same time,the coherence of the simulation and theory can indicate that the simulation model is correct and available.


The article considers the forms of foetuses and mature age II period adults' gallbladder according to the algorithm of gallbladder form definition.


The present invention relates to a cold rolling plant factory owner anti-condensation method and ventilation facilities. The method includes supplying hot air in, the peripheral coil which rely on the floor laying pipe-line high-speed air outlet blowing hot air, hot air curtain formed with the main plant blocking other regions pooling zone in the coil, the coil stacking the peripheral air temperature is above the condensation temperature; further includes a monitoring system according to the feedback coil regional monitoring signal sent timely send hot air ventilation system, so that no condensation coil. The facility comprises: a dew point monitoring system, monitoring points disposed in a coil of each test roll stock area prior arrangement, the control point is provided for monitoring and warning device condensation coil temperature; feeding hot air system, which send hot air the pipeline is laid in the focus coil surrounding aerodromes, with an air outlet (10) on the pipe of the pipe network. The present invention can avoid a large number of condensing coils scrapped accidents, and energy consumption, low annual equipment operating costs, less maintenance overhaul work, a low investment cost.


In a companion paper [1],a transmission-line simulation model for predicting crosstalk involving twisted-wire pairs was developed. In this paper, a simplified model valid for low frequencies is developed. The total coupling is separated into inductive and capacitive coupling contributions. The capacitive coupling contribution is shown to provide a "floor" which limits the effect of reducing the inductive coupling achieved by twisting a wire pair for the unbalanced case and is zero for the balanced case.


The deployment of services --- sets of running programs that provide some useful facility on a system or network --- is typically implemented through a manual, time-consuming and error-prone process. For instance, system administrators must deploy the necessary software components, edit configuration files, start or stop processes, and so on. This is often done in an ad hoc style with no reproducibility, violating proper configuration management practices. In this paper we show that build management, software deployment and service deployment can be integrated into a single formalism. We do this in the context of the Nix software deployment system, and show that its advantages --- co-existence of versions and variants, atomic upgrades and rollbacks, and component closure --- extend naturally to service deployment. The approach also elegantly extends to distributed services. In addition, we show that the Nix expression language can simplify the implementation of crosscutting variation points in services.


This paper proposes a self-calibration based high resolution frequency measurement method. Based on the analog interpolation technique of time-to-amplitude conversion, the measurement of two ways standard time interval is added to reduce the error introduced by temperature change and voltage drift. The measurement data are processed using the least square method to diminish random errors. Test results show that the frequency measurement resolution reaches 12 bits/s and the measurement accuracy is better than ±0.02ppm. Compared with classic measurement techniques, the proposed approach has a broad application prospect as it improves frequency measurement resolution and measurement accuracy with lower cost and convenient calibration.


The purpose of this investigation is to compare the teaching in reading of three pedagogues in form 2 in three different schools from a second language perspective. Among other things it implies to ...


In the present work TiO2 nanotubes (TNT) have been synthesized by alkaline hydrothermal transformation. Then they have been doped with Gd element. Characterizations of doped and undoped TNT have been done with TEM and SEM. The chemical composition was analyzed by EDX, Raman and FTIR spectroscopy. The crystal structure was characterized by XRD. Carbon paste electrode has been fabricated and mixed with Gd doped and undoped TNT to form a nanocomposite working electrode. Comparison of bare carbon paste electrode and Gd doped and undoped TNT carbon paste electrode for 1.0 ×10−3 M K4 [Fe(CN)6] voltammetric analysis; it was observed that Gd doped TNT modified electrode has advantage of high sensitivity. Gd doped TNT modified electrode has been used as working electrode for itopride assay in a pharmaceutical formulation. Cyclic voltammetry analysis showed high correlation coefficient of 0.9973 for itopride (0.04–0.2 mg/mL) with a limit of detection (LOD) and limit of quantitation values (LOQ) of 2.9 and 23.0 μg.mL−1 respectively.


This latest research bulletin in the GEM2 Series considers the degree of global exposure of different industries at the global level, and constructs a measure that is based on the GEM2 Model. It then examines how differences in global exposure across industries are related to style, return and risk characteristics.


A new 3D supramolecular compound,[Co2(Dpq)2(btec)(H2O)6]·2H2O,was obtained from the hydrothermal reaction of cobalt(Ⅱ) nitrate with mixed ligands [1,2,4,5-benzenetetracarboxylate(btec) and dipyrido[3,2-d:2',3'-f]quinoxaline(Dpq)],and characterized by elemental analysis,IR,TG and single-crystal X-ray diffraction. The results reveal that the compound belongs to the monoclinic system with P21/c space group. The cell parameters are a=0.897 8(5) nm,b=2.982 2(16) nm,c=0.705 8(4) nm,β=94.199(6)°,V=1.884 8(18) nm3,Z=2,R1=0.035 0,wR2=0.079 6. The Co(Ⅱ) is coordinated with two nitrogen atoms of one Dpq molecule,one oxygen atom from the bridging ligand btec,and three oxygen atoms from coordinated water molecules,respectively,rendering a six-coordinate mode in a distorted octahedron geometry. Two adjaceut Co(Ⅱ) ions are linked by the bridging ligand btec to construct a dinuclear unit. The 3D supramolecular network of the title compound is formed through hydrogen bonds and π-π stacking interactions. Moreover,the electrochemical properties of carbon paste electrode modified by the compound(Co-CPE) were studied,and the results indicate that the Co-CPE exhibited one-electron redox wave in potential range of 600 to -300 mV due to the metal cobalt ion redox Co(Ⅱ)/Co(Ⅲ). The Co-CPE has good electrocatalytic activity toward the oxidation of nitrite in a 0.1 mol/L HAc-NaAc solution.


The paradigm change from empirical lifetime models to a physics-of-failure based approach for automotive power electronics is driven by need for higher power densities. Hence, the usage of wide-bandgap semiconductor materials is necessary. This is accompanied by higher requirements on the packaging technologies, especially the die attach, in terms of electrical, thermal and mechanical properties. A die attach material meeting these demands is sintered silver which is already widely-used in automotive power electronics. In this study, passive thermal cycling experiments for different die sizes are performed and corresponding finite element simulations are used to find relative correlations.


With the rapid advancement of the digital era, people's lifestyles and consumption patterns have undergone significant changes. Instead of making phone calls for food delivery, consumers now have the convenience of using mobile devices like smartphones or tablets to access online food delivery platforms. Through these platforms, customers can effortlessly select their preferred dishes and restaurants, facilitating quick and seamless food delivery transactions.

Examining consumers' perceptions and viewpoints concerning the user interface and functionalities of food delivery platforms on mobile devices holds significant importance for e-commerce operators in the present scenario.

The questionnaires in this study were devised to gain insights into consumers' perspectives on the user experience and functionalities while using food delivery platforms.

The research findings revealed that the respondents considered "providing diverse payment methods" and "offering promotions" as the two most essential features of a food delivery platform. Moreover, consumers highly value the platform's ability to provide a flexible refund mechanism.


We report on in situ x-ray magnetic circular dichroism experiments at the Fe and V L edges on Fe/V/Fe(110) trilayers. Our results show that the induced V magnetic moment, which couples antiparallel to the Fe one, decreases rapidly away from the interface indicating a short-range polarization in the V layers. This finding confirms recent ab initio calculations.


ABSTRACT In this contribution, Topolski argues that the erasure and denial of Europe's race–religion constellation can help us understand how it has been possible to resurrect the divisive, exclusionary and problematic myth of a 'Judaeo-Christian' tradition in Europe. While this term can be, and has been, used in diverse and contradictory ways in the past few decades, Topolski is most interested in how it masks Islamophobia. To do this, she turns to Europe's denied race–religion constellation. She contends that we cannot understand European racism, past or present, without making the race–religion constellation visible, and that its invisibility today is not accidental. Next, Topolski wants to show how the current resurrection of the term 'Judaeo-Christian' serves to mask and conceal the race–religion constellation. The focus is thus on the exclusion of religions that have not assimilated to the accepted secularized norms of white Christianity, particularly its Aryan/Protestant form, and how this exclusion is connected to the race–religion constellation. In the final part, Topolski explains how the latter might serve the collapsing European project, as well as struggling nation-states, as a scapegoat mechanism to blame Europe's Others for problems Europe has itself created. This leads to their further exclusion and a lack of tolerance in terms of practice and rituals (which might be connected). For these reasons, Topolski argues we need to reject the use of the term 'Judaeo-Christian' and make visible the hidden race–religion constellation.


Summary form only given, as follows. Current theorems suggest that a single hidden layered artificial neural network is sufficient to approximate any continuous function which describes the mapping between two spaces. These theorems do not provide a guide to the practical implementation of networks that are used with real problems. By considering the Taylor series expansion of the equations that describe nodal behavior an alternative description of the performance and limitations of networks can be produced. It was shown that bias is essential for a large class of problems which require even-symmetric mapping. The number of hidden units and the size of the training set required for a given problem is dependent upon the order of the equivalent approximating polynomial. The standard sigmoid output function can be replaced by finite series functions and improved performance can be achieved.<<ETX>>


In this present study, a novel method to fabricate bimetallic Fe-Co catalyst supported on waste silica was investigated for the photo-Fenton-like (PFL) degradation of Methylene Blue (MB) dye. The uniqueness of this work is on the preparation of the catalyst via fluidized-bed crystallization (FBC) process. Under the optimum conditions of initial pH of 3.0, 3.0 mM of H 2 O 2 , and 1.0 g L -1 of FBC-derived Fe-Co/SiO 2 catalyst (fFCS), the maximum response for the decoloration and mineralization efficiencies of 20 mg L -1 of MB in 60 min were 100 and 65%, respectively. Compared to the impregnated Fe-Co/SiO 2 catalyst, the fFCS catalyst exhibited comparable decoloration and mineralization efficiencies, and relatively lower metal leaching for both iron and cobalt. Superoxide radical was unveiled to be the dominant reactive oxygen species in the PFL system over the fFCS catalyst. The catalysts were characterized by Fourier Transform Infrared spectroscopy, Energy Dispersive X-ray spectroscopy and Scanning Electron Microscopy. The results show the successful incorporation of iron and cobalt on the surface of the SiO 2 support material.


The present invention relates to a stator (1) of an electrical machine (2) with a stator (3) with several stator segments (4) on which at least one stator winding (5) is arranged in each case, two adjacent stator segments (4) disposed therebetween spacer elements (6) are hinged together. Is essential to the invention that the stator (1) is pressed together in such a manner radially in the assembled state that the stator (4) abut at least partially against each other.


The invention relates to a retaining ring short-flow manufacture technology, and belongs to the electroslag technology field. The method comprises the steps of A) electroslag hollow steel pipe, namely employing electroslag continuous casting mobile core rod production principle, i.e. consumable electrode for continuously uniform fusing, so that a slag surface rises continuously to start an ingot device after reaching a predetermined height, so as to tract the hollow steel ingot move downwards slowly; the tract speed is in direct proportion with the consumable electrode fusing speed, and the two speeds are balanced; after melting, the steel ingot and the core rod are lifted; the core rod is taken out and the hollow steel pipe retaining ring is completed; B) pulling; C) solid melting; D) mechanical processing, namely processing the internal and external surface of a blank and two transverse planes until ho black dots appear; E) cold expansion, namely deforming the retaining ring by means of hydraulic pressure by using a water press over 8000ton through a special die to obtain a retaining ring that has a high strength that is larger than or equal to 1000 Mpa; F) tempering, namely employing insulating the retaining ring between 35- DEG C and 400 DEG C for a long time after cold expansion to eliminate the deformation pressure.


The issue of lymphadenectomy in the management of endometrial cancer has long been dogged by controversy. The data have been confounded by a number of issues such as selection of patients, trial design, use or non-use of adjuvant radiation, clinicians' expertise and access to resources. The ASTEC trials were designed to examine the role of lymph node dissection and adjuvant radiation in women with endometrial cancer. The lymphadenectomy study concluded "that there was no evidence of benefi t in terms of overall or recurrence-free survival for pelvic lymphadenectomy in women with early endometrial cancer", and that "pelvic lymphadenectomy cannot be recommended as routine procedure for therapeutic purposes outside of a clinical trial''. The ASTEC trials have, however, been extensively criticized, both in terms of trial design and for the fact that mostly low-risk women were randomised to lymphadenectomy and that paraaortic lymphadenectomies were not performed. Subsequent studies have shown a defi nite survival benefi t for women with intermediateto high-risk endometrial cancer who undergo pelvic and para-aortic lymphadenectomy. Tailoring treatment to individual risk factors is gaining more and more supporting evidence.


PART I: PREPRODUCTION. 1. Visual Storytelling. 2. Preproduction. 3. Legal and Ethical Issues. PART II: SHOOT/ACQUISITION. 4. From Lighting to Electrical Energy: Creating and Storing Media. 5. Composition. 6. Audio in the Field. 7. Lighting in the Field. PART III: POST PRODUCTION. 8. The Aesthetics of Editing. 9. Post Production. 10. The Sound Track. 11. Graphics and Effects. 12. Output.


Today, most everyday music listening is an accompaniment to other activities; it is far less common that listening is someone's primary activity, receiving most of their attention. In this article, we present a case study, Listen Up, run by Indigo Project, a mental health organization in Sydney, Australia, in which we explored relationships between participants' responses to the experience and their demographics and styles of music engagement. A sample of 187 Australian residents (aged 20–64 years) who attended Listen Up completed a survey measuring music engagement; emotional responses to the experience; perceived outcomes of the session; pre- and post-measures of stress, mood, and anxiety; and free-text responses to questions concerning their experiences of listening mindfully and any thoughts or feelings that arose during the session. Participants experienced an increased mood and decreased levels of stress and arousal after taking part in Listen Up. Their focused-listening experiences were not simply characterized by enjoying the music; rather, the emotions evoked were varied and complex. We characterized their emotional responses as negative, positive, evocative and expressive, and sad; in addition, participants characterized their own experiences as a cathartic journey resolving into a positive, peaceful, and calm state. Reported outcomes of participating in Listen Up included experiences described as being emotionally challenging, therapeutic, and physically uncomfortable. An affective music engagement style was positively associated with evocative and expressive and sad emotional experiences, and therapeutic outcomes. As a focused-listening experience, Listen Up provides participants with the opportunity not only to attend to music but also to reflect on and process their personal thoughts and feelings. This research provides evidence for the emotional and mental health benefits of focused music listening, such that, focused listening reflects opportunities for strong experiences with music in today's listening landscape.


Processes of getting sense of theoretical knowledge begin from the phenomenon of a posteriori potential possibilities of after-definiteness A. Processes of actualisation of potential possibilities from A by means of before-definiteness В and general-definiteness G are to end non-definiteness N. The mathematical algorithm of the process of sense-formation by means of Galois bijection consists of four steps. Four independent directions gave us four tops of coordinate tetrahedron of three-dimensional projective space.


Coca-Cola European Partners (CCEP), which calls itself the world's largest independent Coca-Cola bottler, is investing in CuRe Technology. CuRe is developing a process to partially depolymerize pos...


Aneurysmal subarachnoid hemorrhage (aSAH) can lead to life‐threatening complications such as vasospasm and hydrocephalus. The incidence of these events is influenced by the volume of intracranial hemorrhage. The Fisher score is a subjective adjudication of SAH volume. We developed an objective semi‐automated method to quantify the volume of intracranial hemorrhage. Moreover, we evaluated the association of aSAH volume with vasospasm and hydrocephalus.

 A custom semi‐automated image segmentation algorithm quantifying aSAH volume was implemented in MATLAB. The volume of hemorrhage was retrospectively measured from non‐contrast brain CT scans with Fisher grade ≥ 2. The algorithm utilized region‐growing and 3D k‐means clustering. Performance was validated against the average of two sets of hemorrhage volumes manually measured. These measurements were obtained from two independent raters who selected regions of interest spanning areas of hemorrhage. The association between blood volume and clinical outcome (hydrocephalus or vasospasm) was evaluated using ROC analysis.

 Fifty‐seven patients were included in this study and 10 patients were used for validation of our method. The ICC between raters for manual measurements of hemorrhage in the validation group was 0.988 (CI: (0.911, 0.997), p < 0.001). Validation of semi‐automated versus manual methods resulted in an ICC of 0.961 (CI: (0.756, 0.991), p < 0.001). Bland‐Altman analysis revealed that the algorithm slightly underestimated blood volume (mean difference = ‐4.11 mL). Hemorrhage volume discriminated for the development of vasospasm (AUC = 0.781) and hydrocephalus (AUC = 0.776).

 Volume of hemorrhage is a key factor that influences the incidence of complications in aSAH. We developed and validated a semi‐automated algorithm for quantifying the volume of aSAH. Vasospasm and hydrocephalus were associated with greater amounts of intracranial blood. Objective measurements of aSAH volume can aid in adjudicating risk of complications among patients with aSAH.


This article addresses the place of music and expressive practice in the production of a social memory of the Cape Verdean diaspora of São Tomé and Príncipe in the late period of Portuguese colonial rule (1940–74). This contrasts the poetics and aesthetics of recorded popular songs depicting São Tomé's experience with the biographical narratives of indentured labourers who were also musicians on São Tomé's plantations. The songs became critical both to politically defining the Cape Verdean diasporic self and to questioning the legacies of indentured labour regimes in the postcolonial present. In their trajectory from an 'archive' to a 'repertoire', the songs also came to embody the experience of a diasporic present. In contrast, the subaltern narratives of migrant musicians account for historically available idioms of subjectivity wherein music practices and socialities are inscribed in an ethics of survival. Besides deepening historical knowledge on São Tomé's diaspora, these 'subaltern pasts' assert an ethical space which allowed individuals to supersede the violence of the colonial labour regime of São Tomé.


PURPOSE: A system and method for the MCOD(Multimedia Contents On Demand) service are provided to maximize the effect of an advertisement while effectively removing the antipathy against the advertisement of viewers by offering discounted MCOD or granting the specific incentive to the viewers. CONSTITUTION: The viewer accesses a system through the network by using an own client(S301). The system allows the client to access(S303). The system transfers the data on the multimedia contents to the client(S304). The client displays the data to the viewer(S307). The viewer browses and selects the desired multimedia contents(S309). The system retrieves the advertisement responding to the selected multimedia contents from a DB(S311). The system displays the advertisement contents to the viewer and asks if the viewer watches the advertisement contents or not(S313). The viewer replies to the proposal(S315). The system checks the reply of the viewer(S317). If the viewer does not watch the advertisement contents, the system sends only the multimedia contents to the viewer(S319). Otherwise, the system discounts the price of the multimedia contents or grants the specific incentive to the viewer(S321). The system sends the viewer the advertisement contents together with the multimedia contents(S323), and the viewer enjoys the advertisement and(or) multimedia contents sent form the system(S325).


Microcystic meningioma is an unusual type of meningioma that has been described under various names including humid, myxomatous, vacuolated, or arachnoid trabecular cell meningioma.1 Histologically, microcystic meningiomas are characterized by numerous cystic spaces filled with edematous fluid and intermixed meningothelial cells of stellate or spider shape. Cytological descriptions of microcystic meningioma have been limited.2,3


Guided by axiomatic design framework,Functional Requirement(FR) and Design Parameter(DP) were formalized in terms of kinematic characteristics set.And the basic FR elements and basic DP elements were also classified.Then,a method for conceptual design of mechanical drive system was proposed.Based on the description of mapping from functional domain to physical domain,the FR decomposition rules were created firstly to guide FR decomposition and search for sub-solutions for each sub-FR.After constructing the mathematical model of searching for the optimal combinatorial solution,ant colony system algorithm was introduced to tackle with this combinatorial optimization problem,which could speed up search process and deal with the possible combinatorial explosion.A design case of to-and-fro yarn-guiding system was presented to illustrate the application of this method.


Background. Pregnant women undergo a variety of physiological changes, and cardiac output (CO) is one of these important changes. During advanced pregnancy, aortocaval compression decreases CO by up to 30 - 40%. Such compression may cause adverse physiological disturbances in both the mother and the baby. Current practice is to nurse pregnant woman with at least 15° lateral tilt. Most studies have used non-invasive blood pressure measurement, which is not the gold standard and does not give a true depiction of the cardiac response to change in position.  Objective. To determine the impact of manual uterine displacement (MUD) on cardiac stroke volume (SV) using the current most accurate non-invasive method, i.e. descending aorta velocity time integral (VTI) with echocardiography (ECHO). This method was used to ascertain the appropriate position to improve CO and provide superior uterine perfusion.  Methods. A prospective case crossover study consisting of 22 women at 36 - 40 weeks of gestation was conducted. The studied positions were supine, 30° tilt, left lateral tilt and manual uterine displacement. Patients received a screening ECHO to ensure normal cardiac structure and function followed by measurement of the descending aorta VTI at each of the positions with 2-minute intervals between position changes .  Results. There was a significant increase in the aortic VTI with all changes in position. The mean (standard deviation (SD)) change for supine-left lateral was 3.68 (0.74) ( p =0.00), supine-MUD was 3.29 (0.72) ( p =0.00) and supine-30° was 2.93 (0.72) ( p =0.00). No significant difference was found when the positions were compared with each other.  Conclusion. Lateral tilt and MUD significantly increased descending aorta VTI (SV).


In this paper we describe the technical details associated with the preparation of Slurm for use on the 12 cabinet XC30 system installed at the Swiss National Supercomputing Centre (CSCS). The system comprises internal and external login nodes and a new ALPS/BASIL version so a number of technical challenges needed to be overcome in order to have Slurm working on the system. Thanks to a Craysupplied emulator of the system interface, work was possible ahead of delivery and this eased the installation when the system arrived. However some problems were encountered and their identification and resolution is described in detail. We also provide detail of the work done to improve the Slurm task affinity bindings on a general-purpose Linux cluster so that they, as closely as possible, match the Cray bindings, thereby providing our users with some degree of consistency in application behaviour between these systems. Keywords-Slurm; ALPS/BASIL 1.3; SPANK plugin; Task Affinity; esLogin; nppcu; QUERY(SUMMARY)


The developed system of the account, processing and the analysis of parameters of operational exploitation and serviceability of a rolling stock are presented in the article.


In this paper, we propose a scheme for the problem of cache-aided multi-user private information retrieval with small caches. All users want to retrieve a file without revealing their demands to the databases. During off-peak hours, all the users will fill their caches, and when required, users will demand their desired files by cooperatively generating query sets for each database. After receiving the transmissions from databases, all the users should get their desired files using transmitted data and their cache contents. This problem has been studied in [X. Zhang, K. Wan, H. Sun, M. Ji and G. Caire, "Fundamental limits of cache-aided multiuser private information retrieval", IEEE Trans. Commun., 2021], in which authors proposed a product design scheme. In this paper, we propose a scheme that gives a better rate for a small value of cache size than the product design scheme. We consider a slightly different approach for the placement phase. Instead of a database filling the caches of all users directly, a database will broadcast cache content for all users on a shared link, and then the users will decide together which part of the broadcasted content will be stored in the cache of each user. This variation facilitates maintaining the privacy constraint at a reduced rate.


On the 14th June 2021 at Bexley Magistrates' Court the appellant, B, was convicted of an offence under s.41D Road Traffic Act 1988 and Regulation 110 Road Vehicles (Construction and Use) Regulations 1986 ('the 1986 regulations'). The factual basis of the conviction was straightforward and was not in dispute. On the 21st September 2020 B was observed 'driving erratically' (at [3]) on Trafalgar Square in Central London. Whilst stationary at a set of traffic lights B was observed by a police officer holding a mobile telephone, the screen of which was illuminated and which B was further observed 'swiping' with his thumb. The police officer stopped B's car and ascertained that B had been using the mobile telephone to play music through the car's sound system and that at the relevant time B had been changing the song. Section 41D Road Traffic Act 1988 (as amended by s.26(1) Road Safety Act 2006) creates an offence of failing to comply with a construction and use requirement specified in the 1986 regulations. This includes a failure:


Speed prediction of surrounding vehicles has received much attention because of its great potential to improve the vehicle's safety, fuel consumption, and efficiency. However, its driving prediction faces significant challenges due to the uncertainty of its driving intention, vehicle dynamics, and the interaction between the predicted object and its surrounding environment. First, the Fuzzy C-mean (FCM) method is used to achieve automatic recognition of driving intentions by offline training using information related to vehicle acceleration; Second, the Gaussian process regression (GPR) method is used to predict future speeds under three different driving intentions using historical and cur-rent vehicle speeds; Third, the three predicted speeds are fused according to the fuzzy classification results of driving intentions by iterative method for 1s rolling prediction; Finally, experimental validation is performed on a 6.6m-long electric mobile robot. The results show that 90.33% of the prediction errors are less than 1m/s in the future 1s speed prediction, and the maximum speed prediction error is 2.45m/s.


Extracting the latent information in high-dimensional and incomplete matrices is an important and challenging issue. The Latent Factor Analysis (LFA) model can well handle the high-dimensional matrices analysis. Recently, Particle Swarm optimization (PSO)-incorporated LFA models have been proposed to tune the hyper-parameters adaptively with high efficiency. However, the incorporation of PSO causes the premature problem. To address this issue, we propose a sequential Adam-adjusting-antennae BAS (A2 BAS) optimization algorithm, which refines the latent factors obtained by the PSO-incorporated LFA model. The A2 BAS algorithm consists of two sub-algorithms. First, we design an improved BAS algorithm which adjusts beetles' antennae and step-size with Adam; Second, we implement the improved BAS algorithm to optimize all the row and column latent factors sequentially. With experimental results on two real high-dimensional matrices, we demonstrate that our algorithm can effectively solve the premature convergence issue.


The utility model relates to a novel radiant cooker, including shell, inner shell, base, micrite board, stone or metal plate for standing a stove on as a precaution against fire subassembly, PCB board and fan, from top to bottom fixed mounting is inside the inner shell in proper order for micrite board, stone or metal plate for standing a stove on as a precaution against fire subassembly, PCB board and fan, and wherein fan fixed mounting is on the base, and stone or metal plate for standing a stove on as a precaution against fire subassembly and fan all link to each other with PCB board electrical property, install a switch knob on the lateral wall of inner shell, switch knob is used for the operating condition of regulation control board, and the control panel is located the inside wall of inner shell, and the control panel links to each other with PCB board electrical property, base fixed connection is in the bottom of inner shell, also being equipped with on the inside wall of inner shell and being used for the fixed chimb of placing the micrite board, the fixed suit of shell is outside at the inner shell, also is equipped with a first through -hole that is used for cup jointing switch knob on the shell. The utility model discloses simple structure, the quick convenience of production equipment, and the safety performance is good.


Linearized equations are used to formulate the theoretical problem of the stability of large-scale zonal flow with vertical shear. The problem is solved in some generality and illustrates the connexion between the solutions already obtained by Rossby, Charney and Eady.


International regimes are composite historical constructions. They are built-up through bricolage, as resource-strapped officials combine operational capacities, frequently turning to outside assistance. Who wins and loses—and why—when organisations are added or subtracted? What happens when inter-organisational relations are recalibrated? Why do regimes cohere as they do? By comparing the development of financial-regulatory regimes and probing other illustrative cases, I offer an explanatory framework that emphasizes the importance of timing and sequencing in determining outcomes. Thinking beyond interstate network effects and switching costs, I distil new data and theoretical insights into how and why temporality matters in global politics. I find that time structures the strategic bargaining contexts that mediate the intense distributional struggles between organisations driving key institutional reforms. The explanatory power of this framework upsets conventional wisdom whereby the distribution of state power, and the dynamics of interstate bargaining, are assumed the critical sources of institutional reform.


Ultrawide bandgap (UWBG) gallium oxide (Ga2O3) represents an emerging semiconductor material with excellent chemical and thermal stability. It has a band gap of 4.5-4.9 eV, much higher than that of the GaN (3.4 eV) and 4H-SiC (3.2 eV). The monoclinic beta-phase Ga2O3 represents the thermodynamically stable crystal among the known five phases . The breakdown field of beta-Ga2O3 is estimated to be 6-8 MV/cm, which is much larger than that of the 4H-SiC and GaN. These unique properties make beta-Ga2O3 a promising candidate for high power electronic device and solar blind photodetector applications. More advantageously, single crystal beta-Ga2O3 substrates can be synthesized by scalable and low cost melting based growth techniques. Different from the molecular beam epitaxy (MBE) and metalorganic chemical vapor deposition (MOCVD) growth techniques, we have developed a low pressure chemical vapor deposition (LPCVD) method to grow high quality beta-Ga2O3 thin films on both native Ga2O3 and c-sapphire substrates with controllable doping and fast growth rates up to 10 um/hr. In this talk, we present the growth, material characterization and device demonstration of beta-Ga2O3 thin films grown via LPCVD. The beta-Ga2O3 thin films were grown on native beta-Ga2O3 (010), (001) and (-201) substrates and sapphire substrates using high purity gallium and oxygen as the precursors, and argon (Ar) as the carrier gas. The growth temperature ranged between 850 ˚C and 950 ˚C. Fundamental material properties including temperature dependent Hall measurements and device demonstration based on vertical Schottky barrier diodes will be discussed.


Rehabilitation of human motor function is an issue of utmost significance affecting millions of Americans. Robot-aided therapy emerged as a promising method to meet the increasing demand for effective rehabilitation services. While robot-aided therapy for upper-extremity provides clinically-proven, efficient rehabilitation, human-interactive robots for lower-extremity therapy have been substantially less successful. Given the labor-intensive nature of conventional, human-administered walking therapy, effective robot-aided assistance is urgently needed. The use of robots and treadmills that may inadvertently suppress the expression of the natural oscillatory dynamics of walking is addressed in this thesis as a possible explanation for the ineffectiveness of robotic walking therapy. To further investigate the natural oscillatory dynamics of walking, the existence and provenance (spinal or central) of a neuro-mechanical oscillator underlying human locomotion was assessed. This oscillator was studied via gait entrainment to periodic mechanical perturbations at the ankle in both treadmill and overground environments. Experiments with unimpaired human subjects provided direct behavioral evidence of the non-negligible contribution to human walking made by a limit-cycle oscillator in the spinal neuro-mechanical periphery. Entrainment was always accompanied by phase-locking so that plantar-flexion perturbations assisted propulsion during ankle 'push-off' while dorsi-flexion perturbations assisted toe-clearance during 'initial swing'. The observed behavior seemed to require a neural adaptation that could not easily be ascribed to biomechanics, suggesting a hierarchical organization between the supra-spinal nervous system and the spinal neuro-mechanical periphery: episodic supervisory control. Thesis Supervisor: Neville Hogan Title: Sun Jae Professor of Mechanical Engineering


The nonlinear failure criterion is employed to determine the active earth pressure and the position of slip surface in this paper.Firstly,the variables Ct andφ t are created by tangents method,then Ct and φt corresponding to different potential slip surfaces are calculated by iteration method and the active earth pressure is obtained by using generalized Coulomb soil pressure theory.The slip surface,which has the maximum active earth pressure,should be the most dangerous slip surface,and the maximum active earth pressure is also what we desired.After comparing with the research results by Mohr-Coulomb linear failure criterion,it is concluded that the active earth pressures behind the rigid retaining walls,which are calculated by the nonlinear failure criterion,will be more practical and accurate,while adopting the Mohr-Coulomb linear failure criterion will provide a lower active earth pressure values,therefore,will cause insecurity in real project.


Dawson structure phosphotungstic acid was prepared and characted by means of UV-Vis and electrochemical methods.The degradation of methyl orange under the irradiation of ultraviolet light was carried out as a probe reaction to study the photo catalytic ability of the catalyst.The results showed that the catalyst exhibited an excellent oxidation-reduction ability when pH2.Under the optimal condition,i.e.catalyst dosage 1.5 g/L,the initial concentration of methyl orange 10 mg/L,illumination time 120 min and pH2,the degradation rate of methyl orange was more than 93.83%.


Abstract . Abstract . Abstract . Abstract . In the urine the crystal presence has little clinical meaning; although its correct identification is of utility in pediatric, due to it provide information for the diagnosis of systemic sufferings, diseases of the urinary routes and possible congenital errors of the metabolism. In order to evaluate the influence of the gender, etario group, socioeconomic condition and the anthropometric nutritional state on the prevalence of cristaluria, 381 apparently healthy children were evaluated; age 1 to 18 years, taken care in three of the ambulatory of the Guacara Municipality, Carabobo State. Was determined anthropometric nutritional state by means of weight/age, carves/age, weight/ carves, greasy area and muscular area in suckling babies, preschool and school students; corporal mass index for adolescents; socioeconomic level measured by modified Graffar. Analysis of urine by optical microscope (400x). Statistical SPSS version 10.1 significance p<0.05. Of the total of studied population 49.1% presented cristaluria, with prevalence in preschool and adolescents (33.2% and 26.2% respectively), with statistically significant predominance in boys (57.8%). The crystal prevalent was the oxalate of calcium in 66.8%, with a statistically significant relation between type of crystal, etario group and socioeconomic layer. In the anthropometric nutritional state was 16,6% of undernourishment. Predominance of socioeconomic layer IV in all the etarios groups. We concludes that cristaluria found in this pediatric population of low socioeconomic level, is independent of the anthropometric nutritional state, although other factors like etario group, gender and socioeconomic level are


Femtosecond near infrared laser microscopes are widely used to perform high resolution 3D imaging of biological samples based on second harmonic generation (SHG) and non-resonant simultaneous absorption of two or more photons at GW/cm2 intensities. However, high contrast imaging of living specimens without any destructive effect is limited to certain laser and exposure parameters with respect to the optical properties of the target. We compared three different femtosecond lasers, including a novel ultra-compact ultrashort fiber laser, in the range of 15-180 fs and repetition rates of 50–300 MHz for optimal non-destructive two-photon autofluorescence imaging. In particular we determined the thresholds for the onset of photodamage effects such as impaired cell reproduction.


We study the Poisson-Lie structures on the group ( ) 2, SU  . We calculate all Poisson-Lie structures on ( ) 2, SU  through the correspondence with Lie bialgebra structures on its Lie algebra ( ) 2, su  . We show that all these structures are linearizable in the neighborhood of the unity of the group ( ) 2, SU  . Finally, we show that the Lie algebra consisting of all infinitesimal automorphisms is strictly contained in the Lie algebra consisting of Hamiltonian vector fields.


The paper demonstrates the application of partial right eigenstructure assignment for designing a output-feedback based wide area damping controller in a power system. The unique feature of the controller is that it uses a quadratic optimization based framework for utilizing the degree of freedom provided by right eigenvectors to selectively improve the damping of poorly located modes while trying to preserve the dominant open loop behaviour of the rest of the system. The input/output signal selection for the wide area controller is based on a controllability metric. An algorithm explaining the framework and its implementation has been tested on the IEEE 68 bus test system. The results show the ability of the controller to utilize a few suitable inputs and outputs to improve the damping of selected eigenvalues with minimal impact on other eigenvalues.


ABSTRACT Measuring change in the mental models of the participants in systems thinking and system dynamics interventions is unavoidable if the relative effectiveness of different interventions in promoting learning is to be assessed. However, existing methods for organizing, representing, eliciting, and mapping mental models are designed primarily to facilitate change in mental models, rather than to measure change, and so new methodologies for measuring change in mental models are needed. This paper defines the necessary features of any methodology that aims to rigorously measure change in mental models of dynamic systems and describes the development and implementation of one specific new methodology designed to fulfill these criteria. An exploratory application of the method to a systems thinking intervention designed to change mental models of the causes of the economic long wave, or Kondratiev cycle, is also described. Results indicate that the intervention produced statistically reliable changes in the content and size of subjects' mental models, as well as the degree of feedback thinking that they contained, but had no significant effect on the degree of detail complexity or dynamic complexity in subjects' mental models. The method was able to capture even subtle changes in mental models due to the intervention, and it can be widely applied to answer important questions about the cognitive effects of alternate interventions. The limitations of the described work and suggestions for future research are discussed.


The invention discloses a multi-head numerical control drilling machine, which comprises a base, a tool changing mechanism, a drill bit mechanism and a feeding mechanism, wherein the base is provided with a workbench, an upright post is fixedly arranged on the base, and the top of the upright post is provided with the tool changing mechanism; a supporting frame is fixedly arranged on the base; the drill bit mechanism is arranged on the supporting frame, the drill bit mechanism is connected with the feeding mechanism, and the feeding mechanism drives a main shaft sleeve of the drill bit mechanism to move along the vertical direction so that a pneumatic clamp arranged on the main shaft sleeve can move along the vertical direction; and the control ends of the tool changing mechanism, the drill bit mechanism and the feeding mechanism are connected with the signal output end of a numerical control system. The tool changing mechanism, the drill bit mechanism and the feeding mechanism are mutually independent, so the drilling machine has clear and compact structure and is easy to maintain; and the mechanisms are controlled uniformly by the numerical control system so as to increase the operation flexibility, improve the production efficiency and reduce the cost. The drilling machine can be widely applied in the machining field.


It demands highly qualified enterprises as the market economy goes f urther with its development. On the other hand, the old administrative mode and system stand in the way of enterprises developing process. For these problems, e nterprises should adapt to variable situations, implementing management innovati on in the reform and development process. This article recommends that enterpris es should grasp opportunity to take definitive measures, along with the innovati on of conception and optimization of organization framework. At the same time, t he enterprises should make efforts in many aspects including working regulations so as to achieve a good result.


By the effect of exterior condition such as the terrain around, geology, environment, weather and inner stress, the construction of tunnel gate is a difficult problem all along. Its construction schedule also affects the whole tunnel construction's speed and quality. So it's very important to have reasonable technology means and inspecting and surveying measures to guide the construction. According to the engineering geology conditions of the portal section of the highway mountain tunnels, with the construction of the Dawan tunnel gate, this paper expounds the relevant measures and methods which can excavate into the portal section of the tunnel. Conducted with the principle of NATM and the feedback from the information of monitoring measures, the construction of the tunnel's portal section has been going on safely and successfully.


The purpose of this research is to know the possibility of the influence of human resources development to employees' performance, to know if there any significant influence and to know how big the influence between human resources development and employees` performance in Bank Syariah Mandiri Medan branch. This research method used associative research method with quantitative data analysis that search the relation between variable X and variable Y. Variable X is human resources development and variable Y is employees` performance. Sample of this research is all of the employees` in Bank Syariah Mandiri office Medan branch. The sample took using total sampling technique with total 35 people. The data collected then analyzed using quantitative data analysis technique. Based on the result of research and continue with analyze collected data using correlation product moment formula, then the result is there is the significant relation and positive in middle degree between human resources development to employees` performance about 0,427 and value of sig (2-tailed)  is 0,010<0,05.  With the value of the influence of human resources development to performance employee's is about 18,2%. Keywords : Human Resources,Employees Performance


Abstract This study aims to evaluate the residual effect of different lipid sources in the diet of Japanese quails (Coturnix japonica) in the rearing phase on the performance and egg quality in the initial phase of egg-laying. In the first stage, 400 Japanese quails aged 21 days were used, being distributed in a completely randomized experimental design, with five treatments and ten replicates of eight birds/replicate Treatments consisted of basal ration (BR) with 2.5% soybean oil; BR with 2.5% corn oil; BR with 2.5% cottonseed oil; BR with 2.5% sunflower oil; and BR with 2.5% canola oil. At 42 days, maintaining the initial design, all quails received a basal ration with soybean oil, in order to evaluate the residual effect of the previous phase on the performance and egg quality in the initial phase of egg-laying (43 - 84 days). The different lipid sources did not affect the performance of quails in the initial phase of production. For egg quality, yolk height, yolk diameter, yolk index, gravity, and Haugh unit (HU) showed better results in the treatment using sunflower oil. There was a residual effect of the use of lipid sources of vegetable origin in the rearing phase diet of Japanese quails on egg quality traits. Lipid sources from soybean, corn, cottonseed, canola, and sunflower seeds can be used as energy sources in the rearing diet of egg-laying quails for not being harmful to their initial performance. The longevity in egg production of quails fed with different lipid sources in the rearing phase was similar.


We are glad to announce that the book Gastric Cancer ( Figure 1 ) has been officially published by the AME Publishing Company in 2015.


In the present paper a new species of the genus Difrion,D. jingyuanensis
isdescribed, which is a serious pest of Pinus tabulaeformis Carr.in Gansu and
ShanxiProvinces in China.Diprion jingyuanensis sp.nov.Female: Head black;antenna black with
scape and pedicel yellowish;palpi deep yellow;mandible dark red except for dorsal surface.
Thorax black with prothorax deep yellow;winghyaline;stigma yellow apically and black
basally,in the black part there is a white spot;veins dark yellow, Abdomen black with terga
1,2,8,lateral parts of tergum 3;and sterna3~5 deep yellow. pubescence on head and thorax
deep yellow.Anterior margin of clypeus deeply and arcuately emarginated;rami of segments 7
to 11about as long as each length of their respective segment;median fovea oval,
moderatelydeep;lateral,coronal and transverse sutures distinct;OOL:POL:
OCL=2:1:1.3.pubescence on clypeus,prothorax and mesonotum longer and denser,Lancet as in
fig.1-1 punctures on head and thorax coarse and dense,nearly rugose; punctures on
abdominalterga very sparse,on lateral parts of terga and sterna dense and coarse.Body length
about 10 mm;antenna 21 to 23-segmented,apical 2~3 segments without raml.Male:Color of
head,wings and pubescence similar to female;thorax and abdomen en-tirely black;legs black
with tibiae and tarsi deep yellow;rami of segments 1 to 11 each about10 times length of their
respective segment;OOL :POL:OCL=2.6:2.6:1; punctureson thorax coarser and
denser,rugose;punctures on abdomen coarser and more numerous.Penis valve as in
fig.1-2.Other characters as for the female.Body length about 8 mm;antenna 23-segmented,with
apical 1~2 segments without rami.Holotype♀,Gansu Province,Jingyuan County,30.Ⅵ.
1989,Zhang You leg;Allotype♂,same data as for holotype.Paratypes 4♀♀,1♂,same data as
for holotype. Paratypes13♀♀,2♂♂,Shanxi Province,Qinyuan County,Ⅳ,1992~1993,Zhao
Jinlong leg.Thetype specimens are deposited in the insect collection of the Forest Protection
Research Insti-tute,the Chinese Academy of Forestry.Hosts:Pinus tabulaeformis Carr. The new
species resembles Diprion liuwanensis Huang et Xiao,but differs from the lat-ter in the color of
the fore wing and the lancet and penis valve.


The swamp antechinus (Antechinus minimus maritimus) is a small insectivorous marsupial inhabiting closed heath and tussock grassland in south-eastern Australia. The species is considered 'Near Threatened' on the Australian mainland. Populations persist on coastal islands off Wilsons Promontory, but their current status is unknown. This study investigated the density, diet and reproduction of the swamp antechinus on Kanowna Island. Data were collected by live trapping in different vegetation types during four trips between August 2003 and January 2004. Higher animal densities (47–129 ha–1) were found for Kanowna Island than for previously studied mainland populations (1–18 ha–1). Examination of scats showed that this species eats a wide variety of prey types, with moth larvae a major dietary component, particularly during the breeding season. Births were estimated to have occurred between 28 June and 8 August, which is a longer period than reported for other populations of this species. Factors including reduced predation, restricted dispersal and increased food availability may be responsible for supporting this dense population.


Vehicle Routing Problem (VRP) is an NP-hard problem. Many solution issues only consider the situation of network featured by infinite connectivity and treat VRP as a problem of average travel time. Network connectivity reliability of the vehicle routing problem caused by emergency has been rarely involved. By use of ant colony algorithm, the connectivity reliability of different sections under emergency situations is compared and then a suitable route is suggested to pass over the congested sections and also the passing capacity of network could be increased.


Underwater vehicles usually work at higher frequencies in a passive acoustic target detection mode,which has a narrow detection range.In order to expand the range,acoustic vector sensors,which work at low frequencies,can be used.When using vector sensors,their directivity is influenced greatly by baffle plates with the limited dimension.Reducing the influence of the baffle plates is an important issue.In this paper,the directivity model of a vector sensor with finite-sized baffle plates is presented theoreti-cally.Comparison between computer simulation and the tank measurements show the validity of the desc-ribed directivity model.


In any federal system, regardless of how it is structured and how powers were originally allocated there is always the problem of which plane of government, if any, should exercise which powers and perform which functions. Selection of extreme centralization would supplant federalism with a unitary government; a choice of an extremely uncentralized arrangement could lead to dissolution of the federal system.


A model to evaluate catalog management and allocation performance in distributed database systems is introduced in this paper.System catalog management is analyzed emphatically,and the important criteria and disciplines of data management and allocation are provided for designers and users of distributed databases.


Despite the ubiquity of violence in world history, and the efforts of scholars and national commissions to diag nose its causes and prescribe solutions, violence remains a major social problem in many parts of the world. Indeed, it is such in part because of these efforts, and because under standing and solutions are problematic. Papers in this issue are reviewed and the respective roles of and relations between national commissions and the scholarly community discussed.


A modified Sprengel pump is described with which permanent gases can be circulated at a rate of 100 ml. min-1 at any desired sub-atmospheric pressure. The pump can also be used for evacuation to better than 1 μtorr and for collection of gas samples of the order of 1 μmole.


Natural killer (NK) cells are a key part in the innate immune system and have the ability to recognize diverse types of tumors and virally-infected targets. NK cells represent an attractive cell population for adoptive immunotherapy due to their ability to kill target cells in a human leukocyte antigen (HLA) non-restricted manner and without prior sensitization. Clinical studies using IL-2 activated NK cells demonstrate significant anti-tumor effects when adoptively transferred into patients with refractory leukemia (mainly AML). However, there has been a more limited response observed in clinical trials for the treatment of ovarian cancer and other solid malignancies. Chimeric antigen receptors (CARs) consist of an antigen-specific single chain antibody variable fragment fused to intracellular signaling domains derived from receptors involved in lymphocyte activation. CARs targeting various tumor-associated antigens have been developed and tested via expression in primary T cells with promising clinical results. However, engineering these T cells must be done on a patient-specific basis, thus limiting the number of patients who can be treated. In order to produce a potential targeted, "off-the-shelf" product suitable to treat patients with diverse tumors or chronic infections, we have generated human pluripotent stem cells with stable CAR expression. Previous studies by our group demonstrate that human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) provide an accessible, genetically tractable, and homogenous starting cell population to develop NK cells. We use a combined approach using "Spin-EB"- mediated differentiation of hESCs/iPSCs, followed by co-culture with artificial antigen presenting cells (aAPCs) that express mbIL-21. Using this strategy, we can generate 10 9 NK cells from a population of approximately 10 6 undifferentiated hESCs or iPSCs. This GMP compatible method is fully defined, without xenogeneic stromal cells or serum. Here, we have expressed both an anti-CD19 (targeting B cell malignancies) and an anti-mesothelin CAR (targeting ovarian cancer cells and other adenocarcinomas) in both hESCs and iPSCs. Using the Sleeping Beauty transposon system, both hESCs and iPSCs have been genetically engineered to express 3 rd generation CARs, which express a single chain antibody fragment recognizing either CD19 or mesothelin, a CD8α hinge region, the transmembrane protein CD28, a co-stimulatory protein 4-1BB, and the activating domain CD3ζ. NK cells derived from hESCs/iPSCs with or without CAR expression are phenotypically similar to NK cells isolated from peripheral blood. These NK cells are CD56 + , CD94 + /CD117 - , Nkp44 + , Nkp46 + , NKG2A + , NKG2D + , and KIR + . In 51 Cr release assays against tumor targets expressing either CD19 or mesothelin, NK cells expressing the corresponding CAR show an enhanced killing ability. In cell lines lacking CD19 or mesothelin expression, the engineered cell lines exhibit equal activity compared to their non-engineered counterparts. Specifically, at a 10:1 effector:target ratio, anti-CD19 CAR + iPSC-NK cells kill 58% of Lax7R cells (a CD19 + ALL cell line) compared to just 5% cell killing by CAR - iPSC-NK cells. Anti-CD19 CAR + iPSC-NK cells also killed 2 other CD19 + ALL cell lines (018Z and Raji) better than CAR - iPSC-NK cells killing 63% vs 18% and 61% vs 8%, respectively. Similar results are seen against the mesothelin + ovarian tumor line A1847. Here, anti-mesothelin CAR + iPSC-NK cells kill 39% vs 14% for CAR - iPSC-NK cells. Currently, CAR-expressing NK cells derived from hESCs and iPSCs are being tested in vivo against both mesothelin + ovarian tumor lines and CD19 + leukemia cells. Together, these studies demonstrate engineering hESCs and iPSCs with tumor-specific receptors provides a novel strategy to produce targeted NK cells suitable for immune therapies against refractory malignancies. Disclosures: No relevant conflicts of interest to declare.


A series of experiments were carried out in a pressurized thermogravimetric analyzer to study the effects of H2S on the reactivity of ilmenite oxygen carrier under pressurized conditions. The total...


Abstract Calcium chloride was used to increase total hardness of hatchery well water from 40 mg/L to 200 mg/L, and two experiments were conducted to evaluate effects on egg diameter and hatch rates of eggs from striped bass Morone saxatilis. In the first experiment, fertilized eggs were divided into two lots; one lot was incubated in untreated well water with a total hardness of 40 mg/L, the other lot was incubated in water hardened to about 200 mg/L. The eggs that were incubated in treated water hatched at a significantly higher rate (70.3%) than the control eggs (53.9%). The mean egg diameter of the treatment eggs (2.45 mm) was significantly smaller than the control eggs (3.14 mm). In a second experiment, eggs were incubated in hardened water for different durations. Fertilized eggs were incubated for 3, 6, or 48 h in hardened water then transferred to well water. Eggs incubated for 48 h in hardened water hatched at a significantly higher rate (44.7%) than those incubated for 3 h (25.3%) or 6 h (31.9%)....


PURPOSE: A cosmetic product containing urethane foam of an ether polymer type is provided to improve reaction stability and to enhance formulation stability, portability, and simplicity. CONSTITUTION: A cosmetic composition contains urethane foam of an impregnated ether polymer type. The urethane foam has a net structure. The density of the urethane foam is 1.0-3.0 pcf. The urethane foam has an open cell structure. The cosmetic composition is a emulsion of W/O type or O/W type. The cosmetic composition is manufactured in the form of a makeup primer, makeup base, foundation, skin cover, lip stick, face powder, lip liner pencil, eyebrow pencil, eye shadow, cheek color, compact powder, powder pact, eye brow, blusher, powder foundation, or airless formulation. [Reference numerals] (AA) EZ93N (polyether type 1); (BB) ZH100KT (polyester type 4]); (CC) ZH100LG (polyester type 5)


Literature has many forms, not only painting, but also writing. Each literature has its own uniqueness and one of the things that is unique is the writing in the novel. Novel is a writing in the form of a book that has various styles of writing in it. These writing styles are called figurative language. Figurative language also has many forms, one of which is simile. Simile is a figure of speech that illustrates or compares something in an explicit, or uncomplicated way. This study examines how many similes are contained in a literary work and explains them. By using descriptive qualitative method, all types of similes, namely (as, like, as...as, as if, and as though) will be discussed in detail. By studying this simile, it is hoped that it will make the readers of the novel better understand and better understand the stylistic message conveyed by the author to the reader.


Many views have been suggested as favourable projections for inclusion in a routine series for investigation of an acutely injured shoulder. The purpose of this paper is to review these projections and their usefulness in a trauma situation. It is accepted that an anteroposterior (AP) view be obtained, however, it is subjective as to whether two AP views, one with internal rotation of the humerus and the other with external rotation, should be employed. The advantages of both of these views are discussed. A further view frequently performed is the AP oblique view. This projection demonstrates the glenohumeral joint in true anteroposterior position and its advantages are reviewed. Other orthogonal projections included in this review are the axillary view, the scapula 'Y' projection and the apical oblique projection. The advantages and disadvantages of these views are outlined and the practicality of their routine use in trauma situations are assessed. On review of the literature it is concluded that a series consisting of an AP view with both internal and external rotation be used, especially when trauma to the glenohumeral joint is suspected, in conjunction with the apical oblique projection. This will provide a comprehensive demonstration of the shoulder region and it is unlikely acute pathology will be overlooked. (author abstract)


In order to resolve the problem of loading mass terrain data in airborne radar real beam ground map (RBGM), multi-resolution terrain database and data loading tactic is designed, which meets the demand of terrain resolution in different range and reduces the system memory consumption. By using and optimizing Terrain defilade algorithm which is fit for far distance condition, whether a ground echo unit is defiladed or not is judged exactly. A look-up table method with backward operation is introduced to solve coordinates transformation for PPI display. After these are used in an airborne radar simulator, the result shows the radar image had high fidelity.


This paper analyzes the course design of A Guide to Success 2, discusses the training the course brings to learners in their learning competence, and then points out the design of the course meets the characteristics of distance education.


The purpose of this study was to investigate the concentration of indoor air pollutants at 63 elementary schools, 41 middle schools and 51 high schools in Ulsan from the beginning of May to the end of December, 2008. To assess the indoor air quality of the various classrooms, the 8 indoor air pollutants such as , CO, , , , TVOCs, HCHO and TBC were measured and analyzed. The mean concentrations of and TBC in the elementary schools were significantly higher than those of middle and high schools (p , , HCHO and TBC were lower than in the vicinity of industrial complexes. The exceeding rate of the school air quality maintenance limits in the 6 air pollutants by law were 6.7%, 3.5%, 1.7%, 18.2%, 13.0% and 18.4% for , , , , HCHO and TBC, respectively. Based on these results and TBC have to be in the order of priority of need to improve the classroom air quality in elementary school of Ulsan.


PURPOSE: To reduce costs for ventilation facility and material for preventing environmental pollution, by supplying an ozonization gas and a photo-resist film removing agent comprising a photo-resist film removing solution from a photo-resist film removing agent supply plate provided counter to a photo- resist film, for removing the photo-resist film. CONSTITUTION: An ozonization gas and a photo-resist film removing solution are supplied toward a substrate 8 from a supply pipe 31 of a photo-resist film removing agent supply plate 30 and a spray hole 33, for contacting to the entire photo-resist film. The photo-resist film on the surface of the substrate 8 which contacted the ozomization gas is acidified and decomposed, for low molecular weight at first. At the same time, a coat of the photo-resist removing solution is formed on the photo-resist film. The photo-resist film of lower molecular weight is dissolved in the photo-resist film removing solution coat, and washed out together with a further supply of solution, so that the photo-resist film is removed from the surface of the substrate 8.


A major contributing factor to the development of breast cancer is decreased functional expression of breast cancer susceptibility gene 1, BRCA1. Another key contributor to tumorigenesis is hypoxia. Here we show that hypoxia increased the nuclear localization of BRCA1 in MCF‐7 and MDA‐MB‐468 human breast cancer cell lines without changing its steady‐state expression level. Nuclear accumulation of BRCA1 was not evident in MCF‐12A or HMEC (human mammary epithelial cell) nonmalignant mammary epithelial cells under the same conditions. Hypoxia also increased the cell surface expression of TRAIL on MDA‐MB‐468 cells. Neutralization of TRAIL precluded the hypoxia‐induced accumulation of BRCA1 in the nucleus, whereas exogenously administered TRAIL mimicked the effect. Treatment of MDA‐MB‐468 cells with TRAIL resulted in a dose‐ and time‐dependent increase in apoptosis. Furthermore, TRAIL‐induced apoptosis in HCC1937 cells, which harbor a BRCA1 mutation, increased synergistically when wild‐type BRCA1 was reconstituted in the cells, and downregulation of BRCA1 expression in MDA‐MB‐468 cells reduced the apoptotic response to TRAIL. These data provide a novel link between hypoxia, TRAIL and BRCA1, and suggest that this relationship may be especially relevant to the potential use of TRAIL as a chemotherapeutic agent.


BACKGROUND
The aim of the study was to confirm the fact that technological water is a significant carrier of Legionella, a potential serious threat to the health of operators of mechanical devices generating contaminated water aerosol.

MATERIAL AND METHODS
Microbiological analyses of water and indoor air were conducted in 8 different production facilities involved in mechanical processing of glass. The study covered 81 samples of water collected from technical water systems. Isolation of Legionella and the determination of total number of microorganisms were processed according to PN-EN ISO 11731-2:2008E and PN-EN ISO 6222:2004P, respectively. Air samples were collected using air samplers and total numbers of bacteria and fungi were determined.

RESULTS
The studies of process water, indicated the presence of Legionella in 27.2% of collected samples. These bacteria were present in both closed and open process water reservoirs at 10 cfu/100 ml to 2.9 x 10(4) cfu/100 ml. The count of other associated bacteria exceeded 10(3) cfu/ml. All strains isolated from Legionella-positive samples were identified as L. pneumophila SG 2-14. In 5 of 8 studied production facilities an increased total number of aerial bacteria and fungi was observed in samples collected in close vicinity of aerosol source.

CONCLUSIONS
To reduce the number of microorganisms in water it is required to introduce technological water quality monitoring and procedures for the cleaning and disinfecting of mechanical devices generating water aerosol.


Traditional healing contributes tremendously to the healthcare desires of natives of traditional settings across the globe, especially with rural people in developing and underdevelop countries Even though traditional healing is common and of great benefit to every society, there is little research on it among the Dagomba, in Ghana, especially colour symbolism in the healing practices. This study's purpose was to explore colour symbolism in traditional healing of the Dagomba. The study fits into cultural anthropology and thus uses observation and interview as data collection instruments, by spending time with a Dagomba traditional healer for one month. The findings were analysed qualitatively and organised thematically, showing that green, red, black and white are the prominent colours used in traditional medicine and healing of the Dagomba people. We recommend further studies of colour symbolism in other cultures of Ghana.


The article discusses the reasons for the popularity of memorials in parts of Denmark during the conversion period (c. 950-990). The forms chosen are considered, as is the subsequent 'absence' of memorials until the middle and second half of the eleventh century. Apart from rune-stones, which continued to be raised until c. 1025/50, and some churches, few memorials are known from the first half of the eleventh century. Likewise, very few memorials are known from Denmark's early Viking Age, the most prominent being the Hedeby boat-chamber grave and the Ladby shipburial. The tenth-century monumental memorials considered are kuml (sign, token, monument), aristocratic burials, rune-stones, ship-settings, mounds, bridges, fortresses and churches. All such memorials, save burials and fortresses, are mentioned on rune-stones. Such memorials relate (as far as we know) to death and burial, family, religion, landscape and power -and probably sometimes law. Also discussed are the Jellinge monuments in relation to Lejre; regional diversity within Denmark; reasons for the building or absence of memorials; the inspiration for new monument types - they were often based on ancient forms - and the re-use of ancient monuments. Questions of when, why and where memorials were created are discussed against the background of the changing religious-cultural-political situation of the period, in relation to anthropological theory and by comparison with the conversion period in England.