OBJECTIVE
To determine the effect of medetomidine on the stress response induced by ovariohysterectomy in isoflurane-anesthetized dogs.

STUDY DESIGN
Prospective randomized study.

ANIMALS
Twelve healthy adult female purpose-bred dogs, weighing 16.8 to 25 kg.

METHODS
Two treatments were randomly administered to each of twelve dogs at weekly intervals: (1) Saline injected IM followed in 15 minutes by isoflurane anesthesia (ISO) induced by mask and maintained at an end-tidal concentration of 1.8% for 60 minutes; and (2) Medetomidine, 15 ug/lkg IM followed in 15 minutes by isoflurane anesthesia (ISO&MED) induced by mask and maintained at an end-tidal concentration of 1.0% for 60 minutes. One week after completion of these two treatments, all dogs were ovariohysterectomized. six receiving each treatment (SURG and SURG&MED). Central venous blood samples (10 mL) were obtained immediately before medetomidine or saline (baseline) and at 30, 75, and 195 minutes and 24 hours after administration of medetomidine or saline in ISO and ISO&MED. In SURG and SURG&MED, samples were obtained immediately prior to injection of medetomidine or saline (baseline) and at 30 (before skin incision), 45 (after severence of the ovarian ligament), 75 (after skin closure), 105 (30 minutes after skin closure, dog recovered and in sternal recumbency), 135, 195, 375 minutes, and 24 hours after the initial sample. Samples were analyzed for epinephrine, norepinephrine, adrenocorticotrophic hormone (ACTH), cortisol, insulin, and glucose. Data were analyzed by analysis of variance and where significant differences were found, a least significant difference test was applied.

RESULTS
Premedication with medetomidine prevented or delayed the stress response induced by ovariohysterectomy in isoflurane-anesthetized dogs.

CONCLUSIONS
The stress response induced by ovariohysterectomy, although significant, is of short duration. Medetomidine safely and effectively reduced surgically-induced stress responses.

CLINICAL RELEVANCE
Surgically induced stress responses can be obtunded or prevented by administration of medetomidine.


The content of the bachelor work is mainly to find out the level of knowledge of the first aid of children at secondary school. Then I compare the level of the knowledge in two regions of Czech Republic. Theoretical part of my work contains facts and recommendations for first aid giving. Also I deal with the actual changes in ERC Guidelines 2010 for giving the prehospital urgent care. Practical part is the evaluation of results of my questions in a test which I assigned in a several secondary schools in region A and the region B. In my work there is also contained my evaluation of the follow-up discussion, which was not included in my research.


AIM: To study the effect of calcitonin gene-related peptide(CGRP) gene transfection mediated by lentivirus on the differentiation of rat bone marrow mesenchymal stem cells(MSCs) to endothelial cells.METHODS: Rat bone marrow MSCs were isolated by density gradient centrifugation combined with adherence method.Recombinant lentivirus vector carrying CGRP gene(Lenti-CGRP) was transfected into the MSCs.The secretion of CGRP in culture supernatants of the transfected MSCs was detected using ELISA method.The cells at passage 3 were divided into three groups: CGRP group(MSCs transfected with Lenti-CGRP),CGRP + CGRP 8-37(an antagonist of CGRP receptor) group and control group(MSCs transfected with PBS).The differentiation of the MSCs was detected by immunocytochemical staining for CD31 and factor Ⅷ-related antigen.The proliferation of the cells was measured by cell counting,and the angiogenic ability of the cells was analyzed using Matrigel assay.RESULTS: The proportion of CD31-and factor Ⅷ-related antigen-positive cells in CGRP and CGRP + CGRP 8-37 groups was larger than that in control group(P 0.05).The numbers of the cells in CGRP and CGRP + CGRP 8-37 groups were significantly increased compared with control group(P 0.05).Lumen-like structures were observed in CGRP and CGRP + CGRP 8-37 groups.The above indexes in CGRP + CGRP 8-37 group were reduced compared with CGRP group.CONCLUSION: Transfection with CGRP gene induces rat bone marrow MSCs to differentiate into endothelial cells and enhances their proliferation,suggesting that CGRP may play a role in the regulation of angiogenesis.


Abstract : This study is a comparison of the 'DO-IT-YOURSELF' (DITY) Household Goods moving program, including both administrative and payment procedures. The two purposes of this comparison are, firstly, to determine if fraud, waste and abuse exists within the Navy system to a significant degree and, secondly, to provide recommendations for beneficial modification of the Navy program. This study was supported through personal interviews at the various service headquarters and supporting staffs, personal observations of member counseling sessions, and interviews with major civilian contractors involved in this program. Conclusions are drawn based upon personal observations and interviews with planning and operational staffs while taking into consideration manning types and levels, political limitations and realities, fiscal responsibilities, and, most importantly, the possibility of degradation of service to the member.


Thank you for reading managing projects a systems approach. As you may know, people have look hundreds times for their chosen books like this managing projects a systems approach, but end up in malicious downloads. Rather than reading a good book with a cup of tea in the afternoon, instead they are facing with some malicious virus inside their laptop. managing projects a systems approach is available in our digital library an online access to it is set as public so you can get it instantly. Our book servers saves in multiple countries, allowing you to get the most less latency time to download any of our books like this one. Merely said, the managing projects a systems approach is universally compatible with any devices to read.


The current urban transportations are mostly mixed traffic, consisting of three kinds of microscopic traffic objects: motor vehicles, non-motor vehicles and pedestrian traffic. In this paper, based on the analysis of traffic characteristics of the above objects, we construct the simulation model for motor vehicles and the cellular automata-based simulation model for pedestrian, and propose vehicle collision avoidance strategies and pedestrian avoidance strategies. This modeling method takes the similarity between models and the real world as the criterion, and effectively overcomes the problems which the accurate mathematical model encountered in mixed traffic simulation. The simulation results shows that, this method effectively simulates some characteristics of mixed traffic, and has broad application prospects in urban traffic planning, traffic demand management, traffic control and other such areas.


During the practical operation of the VQC system in the substation,the voltage of the secondary bus and reactive power should trace the ideal value as closely as possible. Meanwhile,the switching operation of the taps and capacitors should be minimized to protect the equipment. Such a VQC control can be characterized by a typical multi-objective optimizing processing. The traditional nine-zone doesn't account for the impact of the adjustment of the tap on the reactive power,resulting in over-frequent operating of the equipment. To overcome this shortcoming, a multiple-objective optimizing algorithm was proposed for the substation VQC controlling strategy. And,an improved genetic algorithm was adopted for the optimal solving as well. Simulating results indicate that,the proposed controlling strategy and solving algorithm help to reduce the operating times of the tap,and are able to improve the substation voltage,and achieve better controlling performance as well.


A combination of many Solar energetic particle (SEP) events, each one of which is associated with a single eruption, can create one complex intensity-time pro le, that will result in masking the observation of the rst injected particles detected near Earth for each participated eruption. We de ned such SEP events as Multi Eruption Solar Energetic Particle (MESEP) events. We have investigated the intensity-time pro le of 333 solar energetic particle events during the operation time of SOHO mission and studied the associative solar eruptions (CMEs and solar are) from the starting time of each event till the end. We found that most of the events have multi eruption phenomena which might or might not a ect the intensity-time pro le. We found that it is possible to know the real e ect of some of the eruptions during the whole duration of the event, even if their e ect as masked by the rst eruption, by studying the widest possible energy range, the 4He/P ratio and the anisotropy.


We report 1 cm wide monolithic arrays of semiconductor laser diodes emitting output powers up to 90 W CW. Bars with lower fill factors were found to fail by catastrophic optical damage (COD) whereas the highest fill factor bars were limited in output power by heating effects.


Abstract This work suggests a connection between Landau-Zener transition probabilities between two crossing potentials in the classically accessible WKB regime and Landau-Lifshitz transition probabilities in the classically inaccessible WKB regime. It is based on the uniform Airy (UAi) approximation which represents a generalization of quantum transition probabilities for linear crossing potentials with constant coupling. The performance of the UAi approximation is tested by comparison with distorted-wave probabilities for an exponential potential model and illustrated for potentials that determine the intersection of two ab initio vibronic potential surfaces of the NO-Ar system.


The problem of finding the minimum biconnected spanning subgraph of an undirected graph is NP-hard. A lot of effort has been made to find biconnected spanning subgraphs that approximate to the minimum one as close as possible. Recently, new polynomial-time (sequential) approximation algorithms have been devised to improve the approximation factor from 2 to 5/3 , then 3/2, while NC algorithms have also been known to achieve 7/4 + {epsilon}. This paper presents a new technique which can be used to further improve parallel approximation factors to 5/3 + {epsilon}. In the sequential context, the technique reveals an algorithm with a factor of {alpha} + 1/5, where a is the approximation factor of any 2-edge connectivity approximation algorithm.


A flipped current mirror and a flipped voltage follower suited to low-voltage and low power operation is applied to the design of current conveyors (CCII). A new topology (class-A )is proposed operating at 1.5v and featuring simplicity, compactness, low power consumption and bandwidths up to 100 MHz for a 0.5μm CMOS technology.


There is no blueprint for the decolonization of a settler colonial state. To the extent that racial subordination is rooted in and perpetuates colonial relationships of domination and subordination, its eradication will require us to imagine how we can implement the right of all peoples to self-determination. This chapter suggests that the process will involve independent understandings of state, nation, and identity; the development of strategies to empower our communities; and engagement with or support of grassroots movements for self-determination.


We demonstrate a remote microwave/RF transfer technique based on frequency comb. We use high resolution and low drift fiber-loop optical-microwave phase detectors (FLOM-PD) for fiber link stabilization and synchronization between a mode-locked laser and microwave sources. The demonstrated fractional frequency instability between 2.856-GHz oscillators separated by a 2.3-km fiber link is 7.6 × 10-18 and 6.5 × 10-19 at 1000 s and 82,500 s averaging time, respectively.


BOSS FOR WELDING SHEET, METHOD FOR PRODUCING A BOSS AS, AND USE FOR WELDING SHEETS RESISTANCE. BOSS FOR RESISTANCE WELDING SHEETS, CHARACTERIZED BY THE SIDES 11, 12; 18 19 THE BOSS 7, 16 INTERNALLY FORM AN ANGLE TO 45 TO 75 AND EXTERNALLY ANGLE B 60 TO 100 AND IS STRENGTH OF MATTER IN THE REGION OF HIGHER SLOPES OF APPROXIMATELY 50 TO RESISTANCE mATERIAL BASE 17 NEIGHBOR. If bOSS CE USED pARTICULARLY FOR WELDING PLATES OF ALUMINUM ALLOYS.


Within the context of expert performance and the deliberate practice approach, the present study analysed the subjective perceptions about the training tasks of a group of international long distance runners from Spain and Kenya. To do so the athletes fulfilled a questionnaire based on taxonomy of training activities that assessed four dimensions: Relevance, Effort, Concentration, and Enjoyment. Thirty eight male runners participated in this study split into two groups according to their nationality as Kenyan (n= 20) or Spanish (n= 18). All the athletes were long distance runners (10,000 meters, Half Marathon and Marathon). The results showed that training activities such as Competition or tests, Long and short interval training and Tempo runs, were considered the tasks that best characterized their deliberate practice. In addition, these tasks produced more enjoyment and demanded more concentration and effort. The most important differences between groups were that Kenyan runners did not practice some training activities that Spanish runners did such as weights and physical fitness training, running technique or alternative trainings. Also, the Kenyan runners gave more importance to Tempo runs, activity which involved them more concentration than to the Spanish runners.


With the recent increase of lung cancer patients, small sized lung cancers are frequently found withthe widely using of computed tomography(CT). In November 2010, National Cancer Instituteannounced that the routine medical examination with using low dose helical CT reduced the lung cancerdeath rate by 20%, compared with plain chest X-ray. For the small sized lung cancers, several clinicalstudies for limited surgery and stereotactic radiation therapy are on going now. On the other hand, based on the development of radiation and chemotherapy, treatment results of locally advanced lungcancer are improving. Several studies reported that postoperative adjuvant chemotherapy improved theprognosis by 10-15%. Neoadjuvant chemotherapy or chemoradiotherapy have also been reported toimprove the postoperative survival compared with the treatment by surgery alone. Postoperative mortalityrate has been decreased to 0.9% according to the recent report from Japanese Thoracic SurgicalSociety.Like these, surgical treatment for lung cancer has been developed certainly with advancing radiologicaldiagnosis, radiation therapy, chemotherapy, and perioperative management.


This paper describes an application of semantics to sensors to automatically create sensor compositions. Two main contributions of this paper are a sensor ontology and a composition system. The OWL ontology describes user goals, functional and non-functional properties of sensors and sensor composition, while the Region Connection Calculus and Allen's Interval Algebra are used for describing the spatial and temporal properties of sensors. The composition system composes sensors and sensor processes to satisfy a user specified goal. Through experiments, this paper demonstrates the feasibility of semantics for specifying sensor compositions with low reasoning times, and the composition approaches with low composition times in most cases. Some scalability issues with semantic sensor networks are resolved with reasoning, but new composition approaches are needed for large scale use requiring large compositions.


The analysis of the data collected in the Oklahoma City sonic‐boom program gives strong indications that various structures can be excited as Helmholtz resonators. Pressure oscillations were observed to persist in one test house for 1–2 sec after the passage of the shock wave. On occasion, the peak inside pressure exceeded the overpressure of the ground wave. Since the Oklahoma City tests had insufficient flexibility to allow a complete analysis of pressure response, additional studies have been conducted through the use of a 32‐ft plane‐wave tube, at Oklahoma State University. This paper discusses transient‐response spectra of the Helmholtz resonator with the attendant structural response considerations. Experimental results from the Oklahoma City tests and from the laboratory simulations are presented. Mathematical projections are made of possible pressure responses resulting from the flight of a hypothetical supersonic transport.


Objective To explore the contamination status by Legionella in centralized air conditioning system and shower water system in Xicheng district of Beijing.Methods One hospital,three hotels and one bazaar were randomly selected,during June~October 2006,the water from cooling tower of centralized air conditioning systems and shower systems,and the smearing of air outlet and shower nozzle were sampled,the number of samples is 124.The improved technique was used to isolate and identify Legionellae from all samples.Polymerase chain reaction(PCR)was used for confirmation of the suspectable strains.Results 22 samples were Legionella positive from 42 samples of cooling tower water,all the 22 strains were Lp1 type,Lp positive rate was 52.4%,the other three types of samples were negitive.Conclusions Legionella exists in the environment of Xicheng district.Legionella contamination is very serious in air-condition cooling tower,and management of monitoring should be strengthened.Necessary measures should be taken promptly to protect pubic health.


A theory of ultrasonic spin echoes valid for arbitrary spin is presented. Semiclassical vector-model equations are constructed for components of the dipole and quadrupole moment tensors which are excited by ultrasonic pulses in analogy with the well-known Bloch equations. The echo amplitudes are found to depend on the wave number of the pulse, the crystal length, spin density, sound velocity, the density of the medium as well as the magnitude of the appropriate macroscopic dipole or quadrupole moment. Our numerical estimates for a number of physical systems indicate that ultrasonic-spin-echo experiments are feasible for a variety of nuclear and electronic spin systems.


Objective To explore the value of applying modified early warning score(MEWS) in the emergency triage management. Methods A total of 65,147 patients admitted from March to December, 2011 in our emergency department were taken as the control group while 68,092 ones from March to December 2012 as the observation group. The control group was triaged with conventional methods while the observation group with MEWS was referred to relevant regions to receive treatment of different levels according to the scores. The triage accuracy of the two groups and satisfaction rate of doctor and nurse in emergency department for the two systems were compared. Results The accurate triage rate in the observation group was significantly higher than that of the control group(P0.01). The satisfaction rates of doctor and nurses for the emergency triage administration with and without MEWS were 86.7% and 94.6% respectively(χ2=18.61, P0.05). Conclusion MEWS evaluation which can help nurses to triage patients to the right units more accurately is worthy of popularizing in emergency department as an effective tool of triage.


This paper presents the case of Mary Valley's protected catchment, which is located in the northeast Black Sea Region of Turkey, and was declared a national park in 1987. The study area has sensitive ecosystems, with rare and endangered endemic plants. Nevertheless, current unsustainable economic activities, uncontrolled tourism and population migration have adversely affected its sensitive ecological integrity. This research aims to monitor and analyze the landscape dynamics changes of land use-land cover and landscape structure by change detection and landscape metrics in 1987, 1998, 2009 and 2016. The relationship between LULC and habitat changes linked to those of endemic plants were aimed to be determined. The findings indicated that forest areas with the highest loss transformed into grassland, shrubland and bare land areas, while bare land experienced the highest gain. However, forest area has the highest and bare land has the lowest habitat function. Additionally, endemic plant habitats have an inverse relationship with the habitat value of forest and bare land areas and a direct relationship with shrublands. These unsuitable changes can adversely pressure the sensitive landscape dynamics of Mary Valley protected area. Thus, landscape dynamics and their changes should be monitored to protect and manage for the sustainable development of Mary Valley resources.


BASIC PEDAGOGICAL IDEA Abstract French philosopher Jacques Rancière, in The Ignorant Schoolmaster , objects to the model of "explaining teacher". Rancière expresses the aim of this pegagogical programme, in which teacher is decentred, as "intellectual emancipation". This objective of emancipation mandates that the student, still in the educational process, be transformed into an independent subject of knowledge and research and that education be designed in accordance with this. Intellectual emancipation here includes not just the emancipation of the student but also of the teacher. The practical postulate (or the practical axiom) that is to govern this emancipation, according to Rancière, must be the principle of the equality of intelligences. A social reality in which all hierarchies are vanished proceeds from the establishment of an egaliterian epistemological space. The function of the ignorant schoolmaster (teacher) is twofold here; setting the stage for a learning process (i.e. learning process as a research process) which is completely based on student's independent and active use intelligence and at the same time thereby minimizing the inegaliterian ideological ingredients of education. Yet decisive role attached, in Rancière's approach, to the ideal of intellectual emancipation has one negative consequence; the idea of individual study, the idea that individual can discover and activate his/her powers only by his/her own independent study is one-sidedly emphasized. Accordingly, the educative role of dialogue and cooperation (both between student and student and between student and teacher) does not receive the attention it deserves.


Age (years) 17 14 10 Intelligence Normal Normal Normal Growth Weight (kg) 80 (>97th) 65.2 (75th–90th) NA Height (cm) 180 (97th) 165 (50th) NA Head circumference 57cm (75-90th) 51.6cm (5th–10th) NA Craniofacial Blepharophimosis + + + Malar hypoplasia + + + Prominent deformed ears − − − Narrow nose + (with deviated nasal septum and pseudocleft of columella) + (with deviated nasal septum and pseudocleft of columella) +


This study describes the creation of a binary protein–protein interaction map of core cell cycle proteins of Arabidopsis thaliana using two complementary interaction assays, yeast two-hybrid and bimolecular fluorescence complementation. It integrates this map with expression data and describes 357 protein–protein interactions, of which 293 are previously unreported. As in other eukaryotes, cell division in plants is highly conserved and regulated by cyclin-dependent kinases (CDKs) that are themselves predominantly regulated at the posttranscriptional level by their association with proteins such as cyclins. Although over the last years the knowledge of the plant cell cycle has considerably increased, little is known on the assembly and regulation of the different CDK complexes. To map protein–protein interactions between core cell cycle proteins of Arabidopsis thaliana, a binary protein–protein interactome network was generated using two complementary high-throughput interaction assays, yeast two-hybrid and bimolecular fluorescence complementation. Pairwise interactions among 58 core cell cycle proteins were tested, resulting in 357 interactions, of which 293 have not been reported before. Integration of the binary interaction results with cell cycle phase-dependent expression information and localization data allowed the construction of a dynamic interaction network. The obtained interaction map constitutes a framework for further in-depth analysis of the cell cycle machinery.


AIM To develop a method for determining the contents of costunolide and dehydrocostus lactone in Zhituo Jiebai Pill(Gypsum seu Calcitum,Chebulae Fructus,Aucklandiae Radix,etc.).METHODS Reversed-phase HPLC was used to determine the contents of costunolide and dehydrocostus lactone in Zhituo Jiebai Pill.The separation was performed on Yilite-C18 column with acetonitril-water(46∶ 54) as mobile phase.The flow rate was 1.0 mL/min and the wavelength of UV detector was set at 225 nm.RESULTS A good linear relationship was shown when costunolide concentration was in the range of 0.126 4-1.264 μg/mL(r=0.999 9) and dehydrocostus lactone concentration was in the range of 0.176 8-1.768 μg/mL(r=0.999 9).The average recoveries of costunolide and dehydrocostus lactone were 98.60%(RSD of 1.47%) and 97.77%(RSD of 0.77%),respectively.CONCLUSION This method has good specificity,high sensitbility,and good reproducibility.It can be used as quantitative control for costunolide and dehydrocostus lactone in Zhituo Jiebai Pill.


A giant vesicle (GV) is composed of an amphiphile and a closed bilayer membrane with a diameter of 1 μm or more in water. GVs composed of phospholipids are attracting attention as cell models because their constituent molecules, structure, and size resemble those of cell membranes. In the last decade, with the development of GV preparation methods, functionalized GVs that sense a stimulus as an input and can give a corresponding output have been reported as new medical molecular devices. This technical report overviews the applicability of GVs.


In order to reduce the undesirable effect of boundary layer separation and plug‐holing in a naturally ventilated tunnel with shaft for smoke extraction, a new design of baffle has been proposed in this paper. Large eddy simulation (LES) was performed with fire dynamics simulator (FDS), the influence of the angle formed by the boards ( θ ) and the distance between the baffle top and the shaft bottom ( d ) has been investigated. The simulation results show that the smoke extraction efficiency is not simply a monotonic function of the distance d or the angle θ , the influence of d and θ has been discussed, and the mechanism has been investigated. With proper configuration of the inverted V‐shaped baffle, the negative effect of plug‐holing can be eliminated, and the boundary layer separation can also be alleviated; the maximal smoke extraction efficiency is 2.04 times of that in the traditional shaft.


Simple Summary The origin and prevalence of Listeria monocytogenes was studied in dairy cattle farms in order to examine its diversity and determine its possible persistence in manure. The utilization of manure for agricultural purposes is common in many countries. While properly treated and managed manure is an effective and safe fertilizer, foodborne illness outbreaks can occur, as many of the most prominent foodborne pathogens are carried by healthy livestock. It is, therefore, necessary to study the origin and persistence of zoonotic agents in general and of L. monocytogenes in particular, in order to avoid recirculation in farms and reduce risk for human populations. Abstract Listeria monocytogenes is an opportunistic pathogen that is widely distributed in the environment. Here we show the prevalence and transmission of L. monocytogenes in dairy farms in the Cantabria region, on the northern coast of Spain. A total of 424 samples was collected from 14 dairy farms (5 organic and 9 conventional) and 211 L. monocytogenes isolates were recovered following conventional microbiological methods. There were no statistically significant differences in antimicrobial resistance ratios between organic and conventional farms. A clonal relationship among the isolates was assessed by pulsed field gel electrophoresis (PFGE) analysis and 64 different pulsotypes were obtained. Most isolates (89%, n = 187) were classified as PCR serogroup IVb by using a multiplex PCR assay. In this case, 45 isolates of PCR serogroup IVb were whole genome-sequenced to perform a further analysis at genomic level. In silico MLST analysis showed the presence of 12 sequence types (ST), of which ST1, ST54 and ST666 were the most common. Our data indicate that the environment of cattle farms retains a high incidence of L. monocytogenes, including subtypes involved in human listeriosis reports and outbreaks. This pathogen is shed in the feces and could easily colonize dairy products, as a result of fecal contamination. Effective herd and manure management are needed in order to prevent possible outbreaks.


Memorizing has become part of students' study activities in learning. As the learning program is getting harder for primary students, they have got difficulties for maintaining what they see and hear for long time. Method of loci is known as one of mnemonic method that helps student to memorize. Method of loci is a memorizing technique which we can associate the words with familiar places. The method in this research is experimental research with between subject designs. The sample of this research is two groups of fifth grade students. Experimental group was taught by method of loci and control group was taught by reading to memorize the science learning subject. The ability to memorize was measured by giving the achievement test to students. Data was analyzed by Mann- whitney, the results revealed p = 0,0337 (p < 0,05), the experiment group memorize better than the control group. This meant teaching science with method of loci can help students to memorize the learning content better than reading. Keywords: Method of Loci, Memorizing Ability, Learning, Fifth Grade Students


Presents a range interferometry technique to determine radial wind. The wind velocity is obtained by the ratio of range cross-correlation function at positive and negative lags. The feasibility of the method is studied through error analysis. The standard error of the estimated radial wind is derived and its sensitivity to range resolution, sample time and turbulence is analyzed.


Deway, representative of America pragmatism, professes that instinct, desire and want are unchangeable human nature. His philosophy shows clearly the man's nature for living. However,no one pointed out the considerable discrepancy between man and animal,and no one can find that man's adaptability is changeable to the social development. Hence, his theory is limited.


Transl Lung Cancer Res 2020;9(5):1724-1727 | http://dx.doi.org/10.21037/tlcr-20-545 Despite tremendous improvement in i t s c l in ica l management, lung cancer is still the leading cause of cancer related death worldwide (1). It is usually diagnosed at advanced stage and only a minority of patients presents an early and potentially curable disease. However, with positive results of low-dose computed tomography (CT) screening in the high-risk population and with the improvement of diagnostic techniques, early diagnoses can hopefully increase in the near future (2). Therefore, defining the best curative treatment approach for this disease setting is of crucial relevance. Liang and colleagues focused their attention on the subset of epidermal growth factor receptor (EGFR) positive patients cured with surgical resection and drew up a consensus on postoperative adjuvant targeted therapy management (3). As well known, EGFR mutations occur in the 10–15% of Caucasian patients and up to the 40% of Asian ones (4). EGFR testing is recommended in all patients with advanced non-squamous non-small cell lung cancer (NSCLC), but also in patients with pure squamous histology, especially if young and/or nonsmokers. EGFR tyrosine kinase inhibitors (TKIs) represent the recommended first-line treatment in patients with advanced NSCLC bearing classic mutations (i.e., exon 19 in-frame deletions and exon 21-point mutations) (5). Several randomized trials have demonstrated, indeed, the superiority of oral treatment with EGFR TKIs compared to standard platinum-based chemotherapy for this subgroup of patients (4). In the consensus document, authors stated that also NSCLC patients who have undergone a radical resection need EGFR mutation profiling and that EGFRTKIs can replace chemotherapy in patients candidate to adjuvant therapy after surgery, above all in patients who would probably not tolerate chemotherapy treatment, defining "at least 2 years" as the optimal treatment duration. In absence of direct comparisons, the reported adjuvant treatments are heterogeneous: chemotherapy, EGFR-TKI, chemotherapy plus EGFR-TKI (3). Actually, several studies have evaluated the possibility of biological drugs as adjuvant therapy and the results are quite conflicting. What is clear is that, even in early stages, adjuvant treatment with EGFR TKIs could be effective only in those patients whose tumor expresses an EGFR activating mutation. Two are the phase III studies showing that erlotinib for 2 years or gefitinib for 1 year did not improve disease-free survival (DFS) [erlotinib: hazard ratio (HR) 0.90, 95% confidence interval (CI): 0.74–1.10, P=0.32; gefitinib: HR 1.28; 95% CI: 0.92–1.76; P=0.14] or overall survival (OS) (erlotinib: HR 1.13, 95% CI: 0.88–1.44, P=0.33; gefitinib: HR 1.24; 95% CI: 0.90–1.71; P=0.18) compared to placebo in radically resected NSCLC patients (stage IB–IIIA) and not selected Editorial


The theory of magnetospheric recirculation for cyclic electron energization and transport may apply in part to heliospheric transport of jovian electrons if enhanced cross‐IMF propagation occurs at heliospheric altitudes near and below the solar wind transition region. Low altitude, ecliptic‐to‐polar transport would short‐circuit conventional interplanetary diffusion, facilitate rapid access to the polar heliosphere with minimal adiabatic energy losses, and provide a seed population for acceleration to 102−3 MeV energies at the solar wind termination shock and in the heliomagnetotail.


Unlike many other heroines, Maud Gonne lives a separate life with her distinct personality in Yeats's works. Yeats's poems and letters and memoirs disclose a relationship of temperamental and ideological differences between the two a relationship of unrequited love and out-of-body experience, sexual longing and unfulfillment complicated with the dynamics of their spiritual interests as well as psychosexual anxieties. It was a politically charged and mystically coded relationship. This essay attempts to present the different stages of Yeats's poetic presentation of Maud Gonne, her own autobiographical description of her relationship to the poet, and the way his frustrated love complemented his poetic philosophy. It shows how the idea of Maud Gonne served as a direct inspiration for Yeats's poetic creativity and how a sense of devotion, defeat, and melancholy pervades his work, allowing him to recreate an idealized Romantic past. This essay attempts to give a picture not only of Yeats's lyrical portrait of her but also his struggle to understand all she stood for. ********** The intertwined careers of Yeats and Maud Gonne and their artistic and biographical relationship have been a subject of much critical investigation. The relationship, emotional or otherwise, of any great lyric poet with women treated as lovers, muses, companions, and fellow-workers has always been deservedly so. Moreover, as Richard Ellmann points out, unlike the heroines of Swinburne, Rossetti, and Morris, who Yeats thought did not have any separate lives of their own, Maud Gonne does indeed live a separate life with her distinct personality in his works. (1) His poems and letters and memoirs disclose a relationship of temperamental and ideological differences between the two--a relationship of unrequited love and out-of-body experience, sexual longing and unfulfillment complicated with the dynamics of their spiritual interests as well as psychosexual anxieties. It was a politically charged and mystically coded relationship, "fraught with fear, anger, disgust, the underside of an idealising romantic passion." (2) The present essay does not claim to be a real investigation of a problem involved in that highly complex relationship. Instead, it attempts to present the different stages of Yeats's poetic presentation of Maud Gonne, her own autobiographical description of her relationship to the poet, and the way his frustrated love complemented his poetic philosophy. Talking about Mask and Image in The Trembling of the Veil: Four Years, 1887-1891, Yeats in a romantic spirit declares, "We begin to live when we have conceived of life as tragedy." (3) Accordingly, he began to live from January 30/February 1, 1889, the day he met Maud Gonne (1865-1953) the first time through the introduction of John O'Leary. (4) As he discovered Irish mythology through O'Leary who was his personification of the "Romantic Ireland," (5) so too he discovered through him the woman who was to change his life for ever. He refers to the fine spring morning of that fateful day as the time from when "the troubling of my life began." (6) In a retrospective analysis he says that from his youth he was looking forward to an experience in love that would, no matter how painful, shape him as a poet. So be must have dreamed of an exciting and unusual woman to love, just as he must have disliked ordinary, conventional marriage defined and bound by its traditional domesticities. (7) Accordingly, he fell in love with a woman who also had come to see marriage, at least by 1905, as destructive for many women, (8) would never become his wife despite his repeated proposals and would still continue to inspire an intense passion and provide him with images and themes for his poetry. It was Maud Gonne, a tall, beautiful, well-to-do and independent-minded Dublin actress and a violent Irish nationalist, who was to fit Yeats's desire and change his whole attitude to life and poetry. …


ABSTRACT This case study assesses how an Australian University used an online tool (WeChat) to support commencing online Chinese articulation students transition in their studies in response to COVID-19 border restrictions. It investigates how effectively the engagement initiatives met the students' needs and identify areas of improvement. The usage of an online tool allows staff and students to build a relationship and provided students with key information to manage their expectations. This case study demonstrates an opportunity for further research on the effect of online tools to help international students transition.


Greaves and Jolley1 make good points about the National Dementia Strategy, and the need to take a primary care approach to it. While we agree with most of their arguments, they have underestimated the political pressures that shaped the Strategy. Firstly, the care of frail older people is so variable in quality that it is a gift to crusading journalists, with prime time TV programmes and a running campaign in the Daily Mail alarming politicians. Secondly, the relatively marginalised discipline of …


Systolic to diastolic (S/D) ratios of umbilical velocimetry using either continuous-wave or pulsed-wave Doppler ultrasound have been used to assess downstream placental resistance. The purpose of this study was to compare the S/D ratios obtained by both types of instrumentation to determine whether there are significant differences between measurement values. Umbilical velocimetry was performed on 200 high-risk pregnancies in the third trimester using the Angioscan HI to obtain continuous-wave velocimetry and the General Electric RT3600 to obtain pulsed-wave velocimetry. Systolic to diastolic ratios were considered abnormally high if they were greater than 3. One hundred sixty-five patients had normal S/D ratios and 35 patients had elevated ratios on both continuous-wave and pulsed-wave ultrasound. There was no significant difference in the mean S/D ratios obtained by either method for the entire population (continuous-wave S/D 2.81 ± 1.79, pulsed-wave S/D 2.71 ± 1.83, R = 0.98), the normal group (continuous-wave S/D 1.96 ± 0.41, pulsed-wave S/D 1.95 ± 0.40, R=0.91), and the abnormal group (continuous-wave S/D 6.23 ± 1.58, pulsed-wave S/D 6.35 ± 1.52, R = 0.94). Least-square regression was performed to model the relationships between pulsed wave and continuous wave, with both used as dependent variables. The slopes and intercept for the normal and abnormal groups were evaluated and were significantly different (P <.01). The parameter estimates, correlation coefficient, and standard error of the estimate for each model of the entire population were as follows: continuous wave=0.08 + 0.97 pulsed wave, 0.98, and 0.28; and pulsed wave=-0.01 + 1.01 continuous wave, 0.98, and 0.28, respectively. For the normal group, the values were: continuous wave=0.14 + 0.94 pulsed wave, 0.84, and 0.17; and pulsed wave=0.20 + 0.89 continuous wave, 0.84, and 0.17, respectively. For the abnormal group, continuous wave=Systolic to diastolic (S/D) ratios of umbilical velocimetry using either continuous-wave or pulsed-wave Doppler ultrasound have been used to assess downstream placental resistance. The purpose of this study was to compare the S/D ratios obtained by both types of instrumentation to determine whether there are significant differences between measurement values. Umbilical velocimetry was performed on 200 high-risk pregnancies in the third trimester using the Angioscan HI to obtain continuous-wave velocimetry and the General Electric RT3600 to obtain pulsed-wave velocimetry. Systolic to diastolic ratios were considered abnormally high if they were greater than 3. One hundred sixty-five patients had normal S/D ratios and 35 patients had elevated ratios on both continuous-wave and pulsed-wave ultrasound. There was no significant difference in the mean S/D ratios obtained by either method for the entire population (continuous-wave S/D 2.81 ± 1.79, pulsed-wave S/D 2.71 ± 1.83, R = 0.98), the normal group (continuous-wave S/D 1.96 ± 0.41, pulsed-wave S/D 1.95 ± 0.40, R = 0.91), and the abnormal group (continuous-wave S/D 6.23 ± 1.58, pulsed-wave S/D 6.35 ± 1.52, R = 0.94). Least-square regression was performed to model the relationships between pulsed wave and continuous wave, with both used as dependent variables. The slopes and intercept for the normal and abnormal groups were evaluated and were significantly different (P < .01). The parameter estimates, correlation coefficient, and standard error of the estimate for each model of the entire population were as follows: continuous wave=0.08 + 0.97 pulsed wave, 0.98, and 0.28; and pulsed wave=−0.01 + 1.01 continuous wave, 0.98, and 0.28, respectively. For the normal group, the values were: continuous ve= 0.14 + 0.94 pulsed wave, 0.84, and 0.17; and pulsed wave=0.20 + 0.89 continuous wave, 0.84, and 0.17, respectively. For the abnormal group, continuous wave = 0.10 + 0.97 pulsed wave, 0.87, and 0.57; and pulsed wave=0.71 + 0.90 continuous wave, 0.87, and 0.55, respectively. We conclude that there is no significant difference in the mean umbilical artery S/D ratios obtained by either pulsedwave or continuous-wave ultrasound, although there is a quantifiable relationship between S/D ratios obtained by these two methods, with the slopes of the normal and abnormal groups significantly different.


To investigate the effect of the serum levels of adiponectin and C-reactive protein during pregnancy on the perinatal outcomes in women with gestational abnormal glucose metabolism,the serum levels of adiponectin(APN),C-reactive protein(CRP) were measured in 178 gestational diabetes mellitus(GDM) and 154 gestational impaired glucose tolerance(GIGT) women.The age,times of pregnancy,delivery gestation and complications were also recorded.The difference of the perinatal outcomes between gestational diabetes mellitus(GDM) and gestational impaired glucose tolerance(GIGT) women were track and analyzed.The results showed that the serum levels of APN and CRP in GDM group(5.45±2.97,8.53±2.47 mg/L respectively) were significantly different(P0.05) from those in GIGT group(8.96±3.12,4.50±1.49 mg/L respectively).The incidence of macrosomia and neonatal hypoglycemia in GDM group was observably higher than that in the GIGT group.There was no significant difference in the incidence of asphyxia neonatorum,hyperbilirubinemia and transient tachypnea in the two groups.With the deterioration of glucose metabolism from GIGT to GDM,the level of APN on pregnant women was progressively decreased,while the level of CRP increased,resulting in the increase of ill new born babies,especially macrosomia and neonatal hypoglycemia.The experiment indicates that the serum levels of APN and CRP are the possible factors of regulating foetal development in the uterus.


In order to make full use of share memory to improve the data communication efficiency between threads, the use of a slidable dynamic share memory buffer pool is proposed to realize the large volume of data communication between threads, this means, a whole piece of space is applied as the memory buffer pool for all threads, a certain number of unidirectional index queues is constructed, and each index queue represents a data buffet zone. The number of nodels in each index queue can be increased or decreased as required for memory management so that the memory occupied by each data buffet zone can be slided as appropriate. Theo-retical analysis and test results show that the use of slidable dynamic share memorj buffer pool improves the u-tilization of the whole memory buffet zone and the data communication efficiency.


In order to better understand mechanism of activating in fly ash-cement paste,solid state nuclear magnetic resonance(NMR) technology was used.()~(29)Si-NMR test results indicate that the structure of fly ash glasses has been changed from concentrated high-polymerization to scattered low-polymerization by the role of activator.On the process of activating,lots of silicon-oxide bodies with end groups were produced.()~(27)Al-NMR test results show that some octahedron structure and part of the tetrahedron structure of glassiness in fly ash are depolymerized to small molecular structure,and the early activation of fly ash is improved.


Admission to a pediatric intensive care unit (PICU) has been associated with respiratory consequences in children with asthma and carries major implications for management control. Whereas respiratory syncytial virus (RSV) bronchiolitis has been associated with increasing intensity of wheezing, the relationship between RSV‐bronchiolitis PICU admission and future asthma is unclear. This retrospective case‐control study evaluated whether hospitalization in the PICU due to RSV bronchiolitis is more likely to be associated with future asthma in early life compared with hospitalization in a general pediatric ward.


Since the Reform and Opening up,Chinese residents' property income has been steadily increasing,but due to the influence of unfavorable factors in market and system,income gap among residents has been broadening,which not only aggravates the polarization between the rich and the poor,but has a bad effect on social equality.Therefore,it is imperative to control residents' property income gap. China should use the experience of other countries for reference and effectively bridge the income gap for a more balanced growth of property income by strengthening and perfecting the control in financial market,real estate market,social security system and transfer payment system.


Born in 1930, Waldo R. Tobler died on February 20, 2018. He was one of the great American figures of geography, best known for his "first law of geography":Everything is related to everything else, but near things are more related than distant things." During his career as a researcher and teacher at the University of Michigan, then at the University of California at Santa Barbara, he was one of the pioneers in computerization of cartography, and contributed to the mathematical study of (...)


Objective: To observe the clinically therapeutic effect of activating brain and regaining consciousness needling combined with abdomen acupuncture on stroke sequela. Methods: 30 stroke sequelae sufferers were treated with activating brain and regaining consciousness needling combined with abdomen acupuncture, based on selecting points according to TCM syndrome differentiation once a day,six days as a course,four courses in the whole experiment with one- day rest between two courses. Efficacy was evaluated with a certain grade method,motor function with Brunnstrom graded scale,and activity of daily living with Barthel's ADL index,three of which were obtained pre- treatment and post- treatment. Results: Motor function was significantly improved after the treatment( upper limb,u = 6. 24,P 0. 01; lower limb,u = 4. 75,P 0. 01). Ability of daily living was obviously improved with higher ADL index post- treatment compared with pre- treatment( P 0. 05). The total efficiency of treatment was 90%,with 14 cases markedly effective,13 cases effective and 3 cases ineffective. Conclusion: Activating brain and regaining consciousness needling combined with abdomen acupuncture was effective for stroke sequelae,significantly improving motor function of upper and lower extremities and activities of daily living ability through their complementary roles.


To compare day‐to‐day and within‐day variability in glucose‐lowering effect between insulin degludec (IDeg) and insulin glargine 300 U/mL (IGlar‐U300) in type 1 diabetes.


In an attempt to extend the capability of TNO's test facility into a Thermal Wind Tunnel for direct duplication of the in-flight heat flux distribution on supersonic and hypersonic vehicles, an aerodynamic heating scaling technique has been developed which will be described in the present paper. The developed aerodynamic heating scaling technique is based on the analytical equations for convective heat transfer for laminar and turbulent boundary layers that follow from applying the Reynolds analogy which can be used for early experimental verification and CFD validation purposes. Assuming a vehicle flying Mach 6 at 32 km altitude (e.g. like the SHyFE vehicle) the aerodynamic heating scaling technique is developed starting from an elementary isothermal cold flat plate at zero angle of attack and subsequent introduction of wall temperature effects, geometrical scaling effects and angle of attack effects. The presented results show that for the geometrically simple configurations under consideration it is possible to fully duplicate simultaneously the Stanton number and heat flux distribution in a high enthalpy facility at a Mach number significantly lower than the flight Mach number.


Abstract Fluvial quartzite and argillite wedges hundreds of meters thick extend from the fault-bounded south side of the Belt Basin out across the basin for hundreds of kilometers, forming parts of the late Precambrian Belt Supergroup of northwestern Montana, northern Idaho, northeastern Washington, and the Purcell of southeastern British Columbia. From investigations of the Bonner and Mount Shields Formations (upper Belt Missoula Group), five rock types can be identified that correspond to five major depositional tracts on alluvial fan, distal flat, and sea margin surfaces. The conglomeratic rock type contains coarse pebble lenses in matrix supported sand, and accumulated on the proximal parts of the fan surface close to the south bounding faults. Here braided streams deposited gravel in low, longitudinal channel bars and deposited poorly sorted muddy sand between the channels. The conglomeratic rock type passes down the fan to the coarse, crossbedded rock type, containing well sorted, coarse grained, feldspathic quartzose sand in 10 to 40 cm tabular unimodal crossbeds. This rock type represents mostly linguoid and transverse bars that migrated down broad, braided stream channels, working from side to side across the fan surface. Farther down fan, accumulated the fine, horizontally laminated rock type consisting of even beds 10 to 30 cm thick, within which are vertically graded sedimentation units of fine horizontally laminated sand that commonly passes up to rippled crossbedded sand capped by red argillite. This rock type accumulated from traction transported fine sand carried by shallow sheet wash floods across the distal parts of the fan. Suspended wash load continued out onto flats where flow slowed and ponded. Graded couplets of fine sand and silt to clay accumulated from the nearly standing water which repeatedly drained, forming the fine sand to clay couplets of the red argillite rock type. Seaward from the red argillite rock type, where the surfaces were not repeatedly drained, the sedimentary couplets are finer grained, thinner, and the clay was diagenetically altered to chlorite, forming the green argillite rock type. The model derived from the Mount Shields and Bonner appears to apply with minor modifications to other fluvial units of the Belt.


The ocean gravity field has always been an important part of marine scientific research. Combining ship survey data and satellite data to obtain high-resolution and high-precision gravity data attracts many researchers. In this paper, we present two fusion methods of gravity anomaly data, which are data fusion based on the analysis of error trend surface and the data fusion method based on the combination of net function and fractal interpolation. The experimental results show that the data fusion based on the analysis of error trend surface can effectively improve the effect of data fusion. The data fusion method based on the combination of net function and fractal interpolation is not obvious for accuracy improvement, but it shows great potential in terms of detail.


The calcium arsenate-lime-lime sulphur spray has been studied in the laboratory and from the results so obtained it is inferred (1) That the formation of a stable tricalcium arsenate by precipitation from aqueous solution is improbable. The interaction of calcium hydroxide and dicalcium arsenate results in the formation of a continuous series of basic calcium arsenates which are hydrolysed in aqueous suspension. (2) That through the formation of such basic calcium arsenates the addition of lime to dicalcium arsenate reduces the amount of arsenic in solution. This reduction is temporary and on exposure to atmospheric carbon dioxide the original solubility of the dicalcium arsenate is restored. The concentration of soluble arsenic in the dicalcium arsenatelime spray will not be as great as in the dicalcium arsenate spray and the risk of spray injury with the dicalcium arsenate spray is therefore reduced when lime is added. (3) The concentration of soluble arsenic in the dicalcium arsenate and lime spray is reduced by the admixture of lime sulphur with a corresponding reduction of the risk of foliage injury. (4) The precipitation of sulphur from the calcium polysulphides of the lime sulphur is unaffected by the addition of dicalcium arsenate. The addition of lime may result in a diminution of the amount of sulphur so precipitated but such a reaction is dependent on the rate of carbonation of the free lime on the leaf surface. The fungicidal activity due to the calcium polysulphides is therefore unaffected by the addition of dicalcium arsenate but may be adversely influenced if excess of calcium hydroxide be present.


As members of the Society for Personality Assessment and readers of the Journal of Personality Assessment (JPA), a central focus of our activities is assessment. This naturally implies that much of our work is devoted to developing or using diagnostic tests. The Standards for Educational and Psychological Testing (American Educational Research Association, American Psychological Association, and National Council on Measurement in Education, 2014) state that the psychometric properties of tests need to be reported in such a way that users can sufficiently identify whether the test provides evidence of reliability and validity. This naturally implies that the articles about the scales need to give enough information about the way they were developed and evaluated that readers can make this judgment. Whiting et al. (2004) highlighted many potential sources of bias and variation in studies of diagnostic accuracy, including the demographic features of the participants, the severity and prevalence of the disorder, inappropriate choice in the selection of the reference standard, the handling of indeterminate results, and so forth. A later review by the same team found "consistent evidence" for the biasing effects of many of these factors (Whiting, Rutjes, Westwood, Mallet, & the QUADAS-2 Steering Group, 2013). However, there is considerable variability among studies in reporting how they were done or what was found (Honest & Khan, 2002). In an attempt to overcome the problem of inadequate reporting of information regarding the development of diagnostic tests, the Cochrane Diagnostic and Screening Test Methods Working Group, consisting of 25 experts, primarily from medical and epidemiology departments, developed the Standards for Reporting of Diagnostic Accuracy (STARD; Bossuyt et al., 2003). STARD consists of a checklist of 25 items, tapping such areas as the method of recruiting participants, the order of testing, and the reference standard. This is supplemented with a flow chart providing detailed information about the number of people classified at each stage of the study. The Standards were recommended and published by two dozen of the leading medical journals, including the Journal of the American Medical Association, the British Medical Journal, the Lancet, and others. Meyer (2003) wrote an editorial in this journal strongly recommending that authors of articles about diagnostic tests adhere to the STARD initiative, with some modifications making them more appropriate for psychologists. The STARD guidelines (see Table 1) have recently been updated, with the aim of making them easier to use, and incorporating recent evidence about sources of bias and the applicability of the results (Bossuyt et al., 2013). Most of the items remain unchanged, but some have been reworded, combined, or split, so that there are now 30 items grouped into four sections: introduction, methods, results, and discussion. The additional or changed items, keyed to Table 1, include the following:


Objective: To determine the risk factors associated with the development of retinopathy of prematurity (ROP) in the Neonatal Intensive Care Unit (NICU) in the Camino Universitario Adela de Char, January 2016 to december 2017.
Materials and methods: Retrospective type cases and controls study, in premature newborn patients equal to or less than 32 weeks and weighing less than 1,500 grams, who were admitted to the NICU; the sample corresponds to the totality of patients with diagnosis of ROP, randomly selecting a control (normal ophthalmological examination) for each case, paired by gestational age and weight.
Results: Greater prevalence in the male sex in both cases and controls, with 63.3% and 56.7% respectively; the gestational age showed that 50% presented gestational age between 30 to 32 weeks, 33.3% 27 to 29 weeks and 16.7% ≤ 26 weeks with an average of 28.9 ± 2.4 weeks and a mean weight of 1058.2 ± 210.6 grams. Hyaline membrane disease occurred in 73.3% of the cases compared to 46.7% in the controls.
Conclusions: In addition to gestational age <32 weeks and birth weight <1500 grams, it was determined that hyaline membrane disease and the use of pulmonary surfactant behave as a risk factor for retinopathy of prematurity.


After the outbreak of the subprime mortgage crisis,in order to stimulating domestic demand and maintain economic growth,the state council had announced a 4 trillion investment plan.At the same time,how to supervise the use of this large sum of money has aroused wide concern in the public.This paper briefly analyzes people's concerns to the financial supervision caused by the funds of 4 trillion Yuan and the present situation of China's financial supervision,and puts forward some suggestions on perfecting China's financial supervision system.


In view of the particularity of innovative product diffusion under the background of market competition, this paper firstly uses consumer behavior theory to logically deduce the dynamic process of consumer behavior from the perspective of experience theory.,Bass and Lotka-Volterra model are used to describe and model the consumers' perceptual behavior in competitive environment. On this basis, interactive modeling technology is used to model and simulate the diffusion process of innovative products. Finally, the validity of the model is verified by comparing two scenarios with an example.,The research shows that the stronger the enterprise's competitiveness, the higher the market share of innovative products, and the positive impact on consumer perceived value, consumer perceived value can promote consumers' second purchase behavior. Positive word-of-mouth and advertising positively affect consumers' purchasing decisions; negative word-of-mouth negatively affects consumers' purchasing decisions.,The interaction modeling technology and AnyLogic software platform are used to simulate the complexity of consumers' experiential perception so as to build the interaction and competition mechanism among different Agent, which realizes the dynamic simulation of the diffusion process of innovative products. This study provides guidance for enterprises to formulate effective marketing strategies.


Nuclear reactions induced by 2.3 MeV and 14.7 MeV neutrons in some light and medium weigh elements (nitrogen, oxygenm, fluorine, phosphorus, calcium, iron, copper and selenium) have been investigated by activation techniques. The cross-section of (n,p), (n, t), (n, α) (n, 2n), (n, m(^1)) and (n, ɤ) reactions have neen measured, and are discussed with reference to the predictions of the nuclear models. The 2.3 MeV neutrons were obtained from the (^2)H(d, n) (^3)He reaction while those of 14 MeV were obtained from the (^3)H(d, n)(^4)He reaction. The deuterons were accelerated on a 200 KV Cockcroft-Walkton and a 400KV S.A.M.E.S accelerator. A method was developed to determine the absolute flux at both energies using the associated particles method. Recoil particles were counted on a silicon surface barrier detector mounted in the accelerator drift tubes. Absolute disintegration rates were determined by end-window proportional counters, annular liquid sample Geiger Muller counters and on various NaI(Tl) ɤ-ray scinitillation spectrometers. These were calibrated using sources which were standardised using 4πβ counting and or 4πβ/ɤ or β/ɤ coincidence techniques. The active species resulting from irradiation were separated radiochemically before further identification and determination by counters.


The invention concerns a tyre for a two-wheeled motor vehicle and more particularly for a motorcycle. Such a tyre comprises at least one reinforcing structure such as a casing (2) formed with reinforcing elements, anchored on either side of the tyre to a bead (3) whereof the base is designed to be mounted on a rim seat, each bead extending radially outwards through a sidewall (4), the sidewalls being assembled radially outwards with a running tread (5), and comprising beneath the running tread a crown reinforcing structure (6) consisting of at least one ply of reinforcing elements called working ply. The invention is characterized in that, at least locally, the running tread consists mainly of a first polymer mixture (5) and at least of one second polymer mixture having physico-chemical properties different from those of said first polymer mixture, the volume of the running tread being constituted by the first polymer mixture for at least 75 % and the second polymer mixture being distributed discretely.


Purpose. Substantiation of technological solutions for uranium mining by the method of In-Situ Leach Mining (ISL) under the conditions of the high groundwater pressure. Methods. Analysis of mining-and-geological conditions of the deposit, conducting experimental-industrial works at the experimental unit, and processing data from research results. To increase the efficiency and reduce the expenditures for insitu leach mining of uranium, taking into account the hydrogeological peculiarities of the deposit, experimental works have been conducted using the "pumping wells" technology. Findings. The proposed technology helps to reduce the expenditures for acquiring cable products, submersible pumps (the cost of a more powerful pump is much less than the cost of several ones, which are equal to it in power), for the construction of well heads. The dependences have been obtained of the change in the uranium content in the pregnant solution and the recovery coefficient on the L:S ratio (liquid to solid) using the "pumping wells" technology. With a change in L:S from 0.1 to 0.33, the uranium content in the pregnant solution increases from 5 to 225 mg/l, then its gradual decrease is observed. A change in L:S from 0.9 to 2.2 leads to an insignificant change in the uranium content to 100-120 mg/l. Originality. Based on the research results, the dependences have been obtained of the change in the uranium content in the pregnant solution and the recovery coefficient on the ratio of L:S using the "pumping wells" technology. The recovery coefficient has changed in direct proportion to the L:S ratio, hence, for L:S from 0.1 to 2, the recovery coefficient increases from 1 to 87%. Practical implications. A new technology for uranium mining by the method of underground leaching has been developed, which is characterized by low capital expenditures and producing costs of in-situ leach mining of uranium.


A novel dual-band transmission line with flexible phase shifts is presented. To realise dual-band operations, the proposed transmission line is constructed by series-connected coupled lines and open-ended stubs. Using this structure, flexible characteristic impedances and electrical lengths can be designed to operate at two frequencies. Moreover, the proposed dual-band transmission line features a wide range of realisable frequency ratios and a flexible structure. For practical applications, a planar dual-band 3 dB branch-line coupler operating at 2/5.2 GHz is designed using the proposed dual-band transmission line. The simulation and measurement results agree very well with the design theory.


a sociological interpretation of various aspects of the dilemma facing Christian churches, while the last chapter is headed 'A strategy for the future'. One feels that underneath the sociologist is a committed churchman who is strongly aware of the issues that are paramount in this reference group. The book is extremely compact and tightlywritten. Indeed, in order to treat such subjects as 'Cohesion', 'Symbolism', and 'Morality' in an average of twelve pages each, not a word can be


The feeding patterns of 115 consecutive cases of children suffering from protein-energy malnutrition (PEM) seen at Ile-Ife University Teaching Hospital, were investigated. The majority of the children were from Ile-Ife township and nearly all their mothers were working outside their respective homes. The survey shows an earlier mean age (27 months) of onset of kwashiorkor compared with Naismith's (1973) study. About two-thirds of the mothers had stopped breastfeeding their children by the age of 17 months. Artificial milk was introduced briefly, in token quantity, and was replaced by "corn-pap" and other starchy foods such as "yam" and "hard-pap". Over 80% of mothers would not feed their children on meat and fish because they believed these foods would cause worms which, in turn, would cause abdominal pain and loss of weight. Cow's milk, groundnut and cowpeas were said to cause diarrhoea by about two-thirds of the mothers. Our study shows that cessation of breastfeeding, inadequate feeding on artificial milk, and cultural beliefs about appropriate weaning diets for the infants were the major causes of PEM in this part of the world.


On the basis of investigation for shanghai petrochemical company etc,corrosion cause on water cooler and comprehensive protection countermeasures are introduced.Water treatment,anticorrosion material,coating,cathodic protection and cleaning etc.are analyzed.


A useful optical active pyrrolidine compound as a production intermediate of pharmaceuticals, and provides a novel method for producing production intermediate thereof. According to the production method of The present invention, readily mixture of regioisomers obtained by the reaction of the available optically active epoxy compound substituted with an aryl and an amine compound by chlorination, the key intermediate the chloro compound is a body can be produced industrially efficiently. Furthermore, from the above key intermediate can be prepared industrially efficiently an optically active pyrrolidine compound. .BACKGROUND


In the rat pineal, formation of the second messenger cyclic GMP (cGMP) is under adrenergic control. Two important sequential steps mediate adrenergic signal transduction by cGMP, receptor-stimulated nitric oxide (NO) formation by the enzyme NO synthase I (NOS I), and NO-induced cGMP formation by the cytosolic enzyme guanylyl cyclase. With regard to the first step in cGMP transduction (i.e. NO formation) we found, by means of NOS I immunostaining and NADPH-diaphorase staining, that the presence of NOS I was restricted to a subpopulation of pineal cells, generally surrounded by NOS I-negative cells. Considering the fact that NO is able to permeate the cell membrane, the question arises whether the second step in cGMP signalling (i.e. NO-induced cGMP formation) is restricted to the NO-forming cell itself or takes place in neighboring cells as well. It was found that oxyhemoglobin, which scavenges NO but does not enter cells, strongly decreased adrenergic cGMP response. This suggests that a considerable part of adrenergically induced NO stimulates cGMP formation in neighboring cells. Our findings indicate that in the rat pineal the components of adrenergic cGMP transduction are largely distributed among two types of cells: NOS I-containing pineal cells where adrenoceptor stimulation induces NO formation, and neighboring cells in which NO stimulates cGMP formation. OOOOOOOOOOOOOOOOOOOOOO Received: October 13, 1997 Accepted after revision: February 12, 1998 R. Spessert Department of Anatomy, Johannes Gutenberg University Saarstrasse 19–21, D–55099 Mainz (Germany) Tel. +49 06131 393718, Fax +49 06131 393719 ABC Fax + 41 61 306 12 34 E-Mail firstname.lastname@example.com www.karger.com © 1998 S. Karger AG, Basel 0028–3835/98/0681–0057$15.00/0 This article is also accessible online at: http://BioMedNet.com/karger Introduction It is well known that in rat pineal cells cyclic GMP (cGMP) formation is under the control of the neurotransmitter norepinephrine. In contrast to earlier belief that catecholamine-stimulated cGMP synthesis involves presynaptic mechanisms [1], it was later shown that the site of action is postsynaptic, i.e. within pineal cells [2]. Full stimulation of cGMP formation by norepinephrine required activation of both ·1and ß1-adrenoceptors. Pineal ß1-adrenergic stimulation alone leads to a relatively small increase in cGMP [3], whereas simultaneous ß1and ·1adrenergic stimulation results in an amplified increase in cGMP formation [4]. ·1-Adrenergic stimulation alone does not produce any effect on cGMP formation [4]. Concerning the significance of changes in intracellular cGMP levels, recent findings indicate a role for cGMP in the inhibitory control of pineal L-type Ca2+ channel current mediated through protein phosphorylation [5]. Furthermore, an implication of the pineal L-type Ca2+ channel in the regulation of microvesicle exocytosis has been described [6].


In this paper,we discuss a property of the probability measures dominated by g-expectation.We prove that this probability measures can be generated by Girsanov transformation via a process which is uniformly bounded by.


Phase Shift Masks (PSMs) have been widely used in the photomask industry for nowadays. Among several types of PSMs, Alternating Aperture PSM (AAPSM) allows for better resolution within other advantages. This paper deals with micro-trench formation during quartz etching. Micro-trench can produce distortion of the light intensity and lead unwanted results on wafer. Several experiments are performed with respective etch conditions; fluorine (F) gas species, gas flow rates, bias powers, and substrate temperatures while other conditions are fixed. Quartz etching is processed with Inductively Coupled Plasma (ICP) system. Etched morphologies are observed by Scanning Electron Microscopy (SEM), Atomic Force Microscopy (AFM), and a surface profiler to select the best condition as functions of etch parameters. Results show that bias power is the most important factors to decide quartz surface morphologies. Finally, mask image is simulated by AIMS system under given condition.


This paper analyses the causes for lead exceeded of high purity cathode copper,introduces the measure to solve and the results achieved.


Abstract Research on persuasive cues of food placements in entertainment media targeted at children is still scarce. We investigated whether healthy food placements (i.e., fruit) connected to different persuasive cues (i.e., cognitive, affective, and combined) can enhance children's (age 6-11 years old) healthy food choice. A pretest (N = 154) confirmed that the stimulus was understandable and appropriate for children. We then conducted our main experiment (N = 191), measuring children's awareness for positive cognitive and affective cues regarding fruit, fruit evaluation, and fruit choice in response to an audiovisual cartoon. A moderated mediation-analysis revealed that the use of affective cues (i.e., in the affective and the combined condition) increased children's awareness for the positive affective attributes of fruit, which then led to a more positive evaluation. Furthermore, the moderating role of children's body mass index and age were investigated. The effectiveness of cognitive cues regarding cue awareness depended on children's BMI and children's age. The effectiveness of cognitive cues on fruit choice was also moderated by children's age. Implications and avenues for promoting healthy products to children are discussed.


In field, the results showed: PxGV: 1×108PIB/ml+ Bt: 2×106 IU/ml was effective for controlling Plutella xylostella L. After spraying the 5d, it had 56. 94% - 77.46% of controlling effect; After spraying pesticides 7d, it had 50. 80%-75. 89% of controlling effect, and it was secure for green cauliflower.


In this paper, the effects of thermo-diffusion and chemical reaction on a 3 dimensional free convection couette flow of a viscous incompressible and electrically conducting fluid, in the presence of a uniform magnetic field and heat absorption, are analyzed. The plates involved are vertical. The magnetic field is applied in a direction normal to the plates. The plate at rest is subjected to a transverse sinusoidal injection velocity distribution, while the plate in uniform motion is subjected to constant suction and slip boundary conditions. The equations governing the fluid flow are solved using simple perturbation technique. The expressions for skin friction, Nusselt number, and Sherwood number are also derived. Dimensionless velocity, temperature, and concentration profiles are displayed graphically for different values of the parameters entering into the problem, like Pr, Re, M, Gr, Gm, h, A, Sc, So and Kr. The variations in skin friction, Nusselt number, and Sherwood number for different physical parameters are presented. doi: 10.14456/WJST.2015.52


The main purpose of this study is to find out  the perceptions about Mathematics that confuse and anxious 2015 TIMSS participants in Australia, Indonesia, and Singapre. The data in this study is the 2015 TIMSS data that has been released to the public and has available  for development purpose research. The research method used is quantitative method. The population of this study is students' perceptions of Mathematics subject that confuse and worry students aged 15 years in three countries who are studying in 2015, while the sample is 15-year-old students' perceptions  in these countries. The data in this study were in the form of questionnaires which were answered by 16599 students from these three countries. Based on the results of the analysis of variance, there is a significant difference (P <0,000) on students' perceptions about mathematics subject that confuse and worry students in these three countries (Sig. 0,000). The reliability of students' abilities is the same, Australia = 0.74, Indonesia = 0.75; and Singpura = 0.75. The conclusion is most students in these three countries stated "disagree a lot" about mathematics make students confuse and worry.


Two-axis optoelectronic tracking equipments generally use such mode that azimuth and pitch system are independently controlled. It leads to the two structures completely uncoupled, and reduces the state space dimension. But the main problem is that the rotational inertia of azimuth is much larger than that of pitch, which leads its dynamic tracking performance is worse. So to find a more suitable mechanics and more effective control strategy is necessary. Considering the tracking ability, this paper designs BMC (bandwidth mutual compensation) to uniformly correct the error of both the azimuth and pitch system in real time, it is realized by cross coupling control to the azimuth and pitch. The simulation result verified that compared with classical uncoupling system BMS not only guarantees the state space dimension but improves systematic tracking performance about 2" therefore, it is an effective control mode to the two-axis photoelectric tracking equipments.


SUMMARY In the second part of the paper applications are shown for the two-axle unsymmetric running gear and for symmetric running gears with two, three and four wheelsets.


Natural language sentences can be represented as vectors in a high dimensional vector space. Generally, these models are based on bag of words approaches, and therefore they do not fully capture the semantics of sentences which depends both by the semantics of the words, and their order in in the phrase. In this work we propose a sub-symbolic methodology to encode natural language sentences considering both these two aspects. The proposed approach exploits the properties of Geometric Algebra rotation operators, called rotors, to code sentences through the rotation of an orthogonal basis of a semantic space. The methodology is based on three main steps: the construction of a semantic space, the association of ad-hoc rotors to sentence bigrams, and finally the coding of the sentence through the application of the obtained rotors to a standard basis in the


Paul Seydor's essay highlights how Peckinpah drew upon classic forms of cinematic representation while at the same time reconceiving them. By also concentrating on the innovative editing of The Wild Bunch, Seydor helps us appreciate how the film exemplifies both tradition and Peckinpah's unique talent.


Polysaccharide is an important health factor in fruits,which has been found to exert many aspects of biological activities and have a wide application prospect. This paper reviewed the current status of researches on fruit polysaccharide,especially in the resources and utilization,biological activities,and molecular modification of fruit bioactive polysaccharides. Furthermore,the problemes existing in the present researches on fruit bioactive polysaccharides,future research directions and emphasis in this field were briefly discussed.


Transverse combustion instabilities are increasingly problematic in land based and aerogas turbine engines. A common problem in rockets and augmenters, these transverse modes have a circumferential and/or radial structure and are often associated with high frequency oscillations. Depending on its location in the combustor, a flame experiences different parts of a standing circumferential acoustic wave, or in the case of a spinning waveform, a flame sees different parts of the wave structure over time. The current study investigates the response of an annular, swirling nozzle to two limits of the standing wave transverse excitation structure, associated with a pressure node and antinode at the nozzle centerline. The resulting disturbance field is significantly different for these two cases. This paper presents results showing how the disturbance field is composed of long wavelength, multidimensional acoustic disturbances and shorter wavelength convecting vortical disturbances. The flow vorticity originates in the separating boundary layers of the inner and outer annulus and rolls up into larger structures inside and outside of the annular jet. These structures, in turn, merge downstream in a staggered fashion into a single, larger vortex that convects downstream in the annular jet centerline. This paper quantifies the relative strengths and phasing of these disturbances, and discusses the key features of the disturbance field exciting the flame.


A biography of George Green (1793–1841), the celebrated English mathematician and physicist, is presented, together with an analysis of all his published works. Green introduced new concepts and principles in his studies, which not only stimulated the progress of physics in the XIXth century, but re-emerged in the middle of the XXth century and have been found very effective in expressing recent advances in physics.


Partial-order reduction methods form a collection of state exploration techniques set to relieve the state-explosion problem in concurrent program verification. Their use often reduces significantly the memory needed for verifying local and termination properties of concurrent programs and, moreover, for verifying that concurrent programs satisfy their linear-time temporal logic specifications (i.e. for LTL model-checking). One particular such method is implemented in the verification system SPIN, which is considered to be one of the most efficient and most widely used LTL model-checkers. This paper builds on SPIN's partial-order reduction method to yield an approach that enables further space reductions for verifying concurrent programs. 1998 John Wiley & Sons, Ltd.


FIELD: transportation. SUBSTANCE: method for starting an internal combustion engine of a hybrid vehicle includes measuring an engine operating parameter to determine the necessity to assist the electric machine to launch the engine crankshaft; switching off the clutch to disconnect the electric motor from the engine; controlling the transmission for disconnecting the electric machine from the driving wheels; the choice of rotatable transmission components used to facilitate starting the engine in accordance with the measured engine performance parameter. Also carried out: switching on the transmission for connecting the rotating components of the transmission with the clutch; operating the electric machine as an electric motor to rotate the transmission components and to achieve a predetermined speed of the engine crankshaft rotation; and switching on one of the clutches, when the electric machine speed reaches the crankshaft rotation speed, to start the engine. EFFECT: improving the engine starting. 24 cl, 7 dwg


his death as a "wise and good philosopher."2 Bohner's published writings made him one of the great names in philosophical research in the twentieth century. That he was wise and good was the judgment of those who sought his counsel. Most who paid tribute to Bohner at the time of his passing looked at him with North American eyes. But something more can be said. When we view the American years together with the German years thirty-eight of them we see clearly that another adjective must be added to Merton's description. This great philosopher was indeed wise and good, but he was also courageous. His was a courage forged in a pugnacious boyhood, honed in a battle against tuberculosis, tested in opposition to Nazism, and brandished in an intellectual battle to rehabilitate William of Ockham, one of the greatest names in medieval philosophy.


In a realistic radar detection scenario,the disturbance power generated by thermal noise and clutter is unknown.So Gini F proposes a method of estimating the disturbance power and then presents an adaptive successive hypotheses test(SHT) procedure to detect the multiple targets in the same range-azimuth resolution cell of a radar system.However,it is hard to get the threshold for the estimation method.Aiming at the above problem,a new estimation method is put forth and the value of relative threshold is derived.An improved adaptive SHT procedure based on the new estimation method is given.The simulation results show that the improved adaptive SHT procedure has a better detection probability.


Abstract Due to growing environmental concerns, the research on coloration of textiles with reactive dyes is gaining special attention nowadays because of their maximum usage, excellent wet fastness and friendliness. One disadvantage of reactive dye is the hydrolysis, due to which a large amount of dye does not fix the fabric leading to extensive washing. The present study deals with increasing dyeability and functionality of cotton reactive dyeing using chitosan. In conventional reactive dyeing method, salt and alkali's concentration are more used generating effluent, which is harmful for marine life, crops and also for human health. For overcoming this problem, we have used a chemical name as chitosan due to which concentration of salt and alkali will be reduced. Different reactive dyes were applied on woven fabric pretreated with chitosan and comparison was made. Colorfastness properties like rubbing, washing and light fastness of untreated and treated dyed fabric samples were measured using AATCC 08, AATCC 61 (2A) and AATCC 16, respectively. The color strength of these dyed fabric samples was determined by K/S value for comparison.


Cycling and all categories of para-cycling including Handbike are cyclical sports, that is, sports characterized using a specific skill, continuous skill. To separate competitions between cyclists and paracyclists, there is a classification system. The study in aims to design one activity performance and training, to eliminate the division into categories between cycling and para-cycling (Handbike), since this does not favour the integration and sporting inclusion of the two groups of athletes. The differences in performance will be identified between: cyclists and paracyclists with spinal cord injury or amputation of the lower limbs (H). Then will proceed to design and verify an activity capable of making the two categories compete and train together, eliminating the differences in performance through the use of a " counterweight " and using a mixed training, HIIT (High Intensity Interval Training) and Endurance. The sample taken into consideration is composed of 5 cyclists and 5 paracyclists (H) aged between 19 and 38 years. To achieve the goal, the study was based on the method of analysing the scientific literature, detecting the various parameters in the race and using mathematical statistical methods, such as Multiple Regression and the T-Test for independent samples. The analysis of the results of this study shows that; between cyclists and para-cyclists who participated, there are substantial differences in performance, thanks to the data obtained from multiple regression, in which we find an R-squared value that is .999975008, also the only positive coefficient among the independent variables is that of power (6.760634791). This means that of all the reported values, it is the only one that directly affects


Chemical imaging in fresh and aged Cannabis leaves, with three matrices in different concentrations by LDI and MALDI(−) MS and IMS.


We have applied cationic liposomes, consisting of an equimolar mixture of pyridinium amphiphile SAINT-2 and the phospholipid DOPE, as carriers for oligonucleotides (ODNs) and plasmids, and investigated the mechanism of lipoplex-mediated gene and ODN delivery in vitro. Cryo-electron microscopy and small angle X-ray scattering revealed that PEG-lipids stabilize the lamellar phase of the lipoplexes. As a result, the internalized lipoplexes, including their cargo, remain trapped in the endosomal/lysosomal pathway. Acyl chain-length dependent transfer of the PEGylated lipid derivatives from the complex enables adaptation of the hexagonal phase. This is imperative for release of ODNs and plasmids across the endosomal membrane into the cytosol, and nuclear homing. Thus delivery resumed when the complexes had been coated with exchangeable PEG-lipid derivatives, the kinetics of which was dependent on the length of the acyl chains (PEG-ceramide and SAINT-PEGs). To investigate the significance of DOPE's preference to adopt (in isolation) a hexagonal phase in the overall mechanism of lipoplex-mediated transfection, the properties and transfection efficiencies of mixed cationic lipid SAINT-2/DOPE lipoplexes were compared to those containing lamellar phase forming dipalmitoylphosphatidyl-ethanolamine (DPPE). Following an interaction with anionic vesicles, to simulate lipoplex-endosomal membrane interaction, SAINT-2/DOPE lipoplexes show a perfect hexagonal phase, whereas pure lamellar phase SAINT-2/DPPE lipoplexes form a mixed lamellar-hexagonal phase upon such interactions. This transition to the hexagonal phase is crucial for anionic lipid-induced dissociation of DNA or oligonucleotides from the lipoplexes, as emphasized by the absence of significant release when such a transition is frustrated at a variety of conditions. However, the efficiency of nucleic acid release from either complex does not correlate with the two-threefold higher transfection efficiency or nuclear delivery of ODNs observed when SAINT-2/DOPE lipoplexes were incubated with cells. Interestingly, rupture of endosomes following a cellular incubation with ODN-containing SAINT-2/DPPE complexes dramatically improved nuclear ODN delivery up to a level, which was similar to that observed for SAINT-2/DOPE complexes. Our data demonstrate that although formation of the hexagonal phase in lipoplexes is a prerequisite for nucleic acid release from the complex, it appears highly critical


Seeking dialogue with the knowledge produced in anthropology about the category heritage this paper analyzes a process in Europe, which is the effort to revitalize and preserve a type of grazing known as transhumance. The transhumance, typical of countries of the Mediterranean climate, with strong temperature fluctuations between winter and summer, is characterized by the displacement of people with their livestock over long distances. This activity has been considered threatened to disappear in Europe. The reflection on the "patrimonialization" of this activity is the purpose of this article. The analysis of the construction of a system of objects in this context and its role in the formation of subjectivities, cultural identities and assertion of rights are central goals of this work.


The problem of increasing the level of information security of the national economy is actualized in the article. Scientific approaches to the concept of "information security of the national economy" are systematized. The dual impact of digitization on the emergence of opportunities and threats to the functioning of the national economy is substantiated, which necessitates the development of tools to improve the level of reliability of economic information. The state of information security in modern computer systems of economic data processing is analyzed; requirements and directions of development of highly reliable computer systems for processing of economic data are substantiated. New scientific and scientific and technical achievements in the field of developing an optimal data backup in the economic sphere were obtained with the use of the non-positioned numerical system in residual classes, which improves the security and reliability of information processing.


A method for secure single-channel transmission of data between the computer nodes (RK1, RK2) of a computer network a) a failsafe executed computer node (RK1), the at least two operating in parallel, connected by a node internal communication channel with each other computers (R1A, R1B, R1C) which via a node external communication channel (KAN) to another such computer node (RK2) user data and determined from the user data and these locking in the transmission data redundancy sends, characterized, b) that the determination of the correct redundancy data to user data, which transmits a computer (R1A) via the node external communication channel, exclusively in a computer (R1B, R1C) is carried out or by sequential calculation, wherein said redundancy data in a computer (R1A) exclusively from determined in a different computer (R1B, R1C) partial result are determined, wherein c) the redundancy data are determined from the useful data using a table, in which each computer in a data memory under specified addresses ...


Single factor experiments and orthogonal test packet method combined with the actual situation were performed to determine the best conditions for the ultrasonic method and the traditional hot water extraction of polysaccharide of Hericium.The experimental results showed that the impact of various factors on Hericium mycelium polysaccharide extraction rate was in the order of liquid ratio ultrasonic treatment time ultrasonic treatment temperature.The optimum conditions were as follows: ultrasonic processing time of 20 min,extraction temperature of 50 °C,liquid ratio of 1∶15,extracting 2 times.Compared with the traditional hot water extraction method,the ultrasonic extraction time was shortened four-fifths,and the polysaccharide extraction rate was 40% more.


Tracking order analysis is a useful tool for rotating machinery.Computed order tracking method overcomes the bugs of the traditional tracking order analysis that is so complex,costly and low precision.By the means of software resampling,it easily turns the time-domain vibration signal to the degree-domain vibration signal.This paper gives the integrated computing steps of the computed order tracking method based on spline data interpolation,so gives an integrated feasible scheme for the resampling process of computed order tracking method.Then the paper finally gives a result of this method applying to the aero engine's changing speed process.


Abstract : The helium tracer gas fine leak seal test, as specified in MIL-STD- 883, method 1014, test condition A, based on the 'back-pressurization' technique for determining the hermeticity of microelectronic device packages, is described. The sensitivity of seal test parameter variations to package leak rate measurement test results is analyzed in detail by a systematic variation of exposure pressure, exposure time and dwell time over the complete range of microelectronic package volumes. Analysis results verify the need for specifying standard seal test conditions, for defined package volumes, as required in MIL- STD-883, to insure that the specified level of package hermeticity will be achieved. Microelectronic device reliability as related to package volume leak rate (atm cc/sec) is discussed. Microcircuit failure modes and associated failure mechanisms dependent on package hermeticity are presented.


Funds gap of securities firms is somewhat one kind of that of excess credit,which is mainly caused by excess risk faced by them.By impawned loans,funds gap of excess credit can be filled,and risk can also be balanced on the other hand,while the key is effective risk balance design.


Suspensions, which are filled at loading levels approaching their maximum packing fractions, present special processing challenges. The flow and deformation behavior of such highly filled suspensions are dominated by strong slip effects. Furthermore, during pressure driven flows of these suspensions, the polymer matrix can filter out, giving rise to demixing and unstable flows. In this study, the capillary flow and extrusion of highly filled suspensions of ammonium sulfate and other salt fillers in a poly(butadiene acrylonitrile acrylic acid), PBAN matrix were investigated. The experimentally observed instabilities were elucidated in conjunction with a proposed mechanism, involving slip and filtration rates. This mechanism suggested greater affinity to unstable flows with relatively lower matrix shear viscosity, greater particle size of the filler, and greater convergence ratio; all of which were experimentally verified.


The paper describes our work on reengineering legacy procedural software systems to object oriented equivalents. The method proposed is based on applying design transformations to appropriate scenarios preserving behaviour. Our work is illustrated via a CASE tool which has been developed allowing an object oriented structure to be extracted from structured C code.


Availability of various ICT tools and accessibility of electronic information resources across the world has fuelled the growth of e-learning. The present paper focuses on the use and awareness of various e-resources available in the Punjab Agricultural University library. The findings of the study reveal that the electronic resources have become an integral part of the information for various features such as 'easy download', 'fast searching capability', etc. Despite the fact that e-resources have eased the task of research, respondents still prefer information in both formats  'print as well as electronic'.