The use of ETBE (ethyl- tert -butylether) as gasoline additive has recently grown rapidly. Contamination of aquatic systems is well documented for MTBE (methyl- tert -butylether), but less for other gasoline additives. Due to their mobility they may easily reach drinking water collection areas. Odour and flavour thresholds of MTBE are known to be low, but for ETBE and TAME (methyl- tert -amylether) hardly information is available. The objective here is to determine these thresholds for MTBE, ETBE and TAME, and relate these to concentrations monitored in thousands of samples from Dutch drinking water collection areas. For ETBE odour and flavour thresholds are low with 1–2 l g L (cid:2) 1 , for MTBE and TAME they range from 7 to 16 l g L (cid:2) 1 . In most groundwater collection areas MTBE concentrations are below 0.1 l g L (cid:2) 1 . In phreatic groundwa- ters in sandy soils not covered by a protective soil layer, occasionally MTBE occurs at higher concentrations. For surface water collection areas a minority of the locations is free of MTBE. For river bank and dune infiltrates, at a few locations the odour and flavour threshold is exceeded. For ETBE fewer monitoring data are available. ETBE was found in 2 out of 37 groundwater collection areas, in concentrations below 1 l g L (cid:2) 1 . In the surface water collection areas monitored ETBE was found in concentrations near to the odour and flavour thresholds. The low odour and flavour thresholds combined with the high mobility and persistence of these compounds, their high production volumes and their increased use may yield problems with future produc- tion of drinking water.


Pedestrian simulations have recently focused on top-down implementations ignoring more computationally intensive agent based dynamics. This paper presents a framework for agent based modelling on the Graphics Processing Unit (GPU) which demonstrates large scale pedestrian simulation and rendering. GPU hardware offers significant performance for dynamic large crowd simulations, however the process of mapping computational tasks to the GPU is not trivial and expert knowledge is required. An agent based specification technique is therefore presented, which allows the underlying GPU data storage and agent communication to be hidden. The framework allows the use of static maps to set static environment obstacles and a zoning technique is described for route planning. Parallel population feedback routines are also used to implement Level of Detail (LOD) rendering which avoids any costly CPU data read-back. .


A new bi-dimensional empirical mode decomposition (EMD) is proposed for sparsely decomposing a textured image into two components, namely, a single intrinsic mode function (IMF) and a residue. The sifting process of this method employs morphological operations to detect the ridges and troughs of images, and uses weighted moving average algorithm to estimate envelopes. The texture of the image is automatically retrieved by extracting the single IMF. The method can solve two key problems, namely, mode mixing and inappropriate interpolation of 2D scattered data. Fast algorithm is also presented for reducing the calculation time to several seconds only. This approach is applied to process simulated and real images.


(57) Abstract: iridium and using a catalyst comprising at least one second metal selected from the lanthanide series, a vapor phase process for the carbonylation of esters and to any carboxylic acid lower alkyl alcohol. Desirably, the iridium and the second metal is deposited on activated carbon as support material. In a preferred aspect of the invention, the vapor phase method, the catalyst, methanol and steam consisting of halide and carbon monoxide, by contacting with the carbonylation process conditions, acetic acid, methyl acetate or mixtures thereof useful for the production of.


It is shown that cyclic heating and cooling considerably accelerate kinetics of process of the steel chemical thermal processing. Laws of formation of the strengthened layers are considered at thermocyclic nitrocementation of the steel 20Kh. Production tests of machine parts after the chemical thermal and chemical-thermocyclic processing were performed. The structure, phase composition and intensity of wear process of a blanket depending on a number of cycles are studied.


characterized by a triad of symptoms: qualitative impairments in social interaction, delayed or impaired communication abilities, and stereotyped patterns of behavior or restricted interests (American Psychiatric Association [APA], 2006). In the psychological sciences, autism researchers have focused largely on the identification of and treatments for social and cognitive deficits. Visual perception provides an important source of information for both social and cognitive processes. Indeed, understanding how people with autism perceive their environments may be a necessary step toward understanding the social and cognitive deficits associated with autism. Consistent with this, substantial research has examined the relationships between autism and visual perception (see, e.g., reviews by Behrmann, Thomas, & Humphreys, 2006; Dakin & Frith, 2005; Happé & Frith, 2006; Pellicano, Jeffery, Burr, & Rhodes, 2007; Schultz, 2005). Within the last decade, numerous researchers have focused on the question of how observers with autism perceive movement, specifically, the movements of dotdefined surfaces and people. Initial studies reported that observers with autism show compromised visual sensitivity to coherently moving surfaces defined by randomly located dots but not to point-light displays (PLDs) of human movement. More recently, the opposite pattern of results has emerged, with reports of typical levels of visual sensitivity to coherently moving random dot surfaces and significant deficits in visual sensitivity to coherent human motion. The goal of this review is to examine this increasingly complex literature and to suggest ways to integrate apparently divergent findings. Because autistic disorders show substantial heterogeneity, the term autism spectrum disorder (ASD) is used to reflect this behavioral continuum. ASD is not incompatible with normal or superior intelligence (Schultz, 2005). Indeed, most studies of people with ASD are conducted with individuals whose intelligence falls within the average to above-average range. These include studies of people with Asperger's syndrome (AS) who experience deficits in social interaction and stereotyped or rigid behaviors in the absence of early language delay (APA, 2006; Wing, 2000). Many studies of ASD and AS include individuals with normal IQs, because those on the lower functioning end of the spectrum may have difficulty completing experimental tasks and often have comorbid disorders that complicate the implementation and interpretation of psychophysical performance.


By some time series methods and regression analysis methods of SAS system, we do some prediction and analysis for disaster area and destroyed area of crops in our country. It is shown that the accuracy of prediction is fairly good. This paper affords useful method for the disaster prediction in our country.


ABSTRACT Between Nov. 6, 1917, and May 15, 1918, 104 cases of erysipelas were treated at the base hospital at Camp Cody. Most of these began on the face. The disease followed drainage of the mastoid in seven cases, abscess of the scalp in three cases, demonstrable ulcer in the nose in three cases, hordeolum in one case, and burns of the face in one case. The remaining ninety cases were called "idiopathic." On certain occasions an influx of such cases was noted after a period of high winds and dust storms, such as characterize this place and favor the development of inflammations of the mucous membranes of the head generally.Although only one patient died as the result of erysipleas, the disease was responsible for a total of 2,497 hospital days, making it a matter of some importance to determine the best method of management and establishing it as a


A CMOS image sensor is provided to expand the dynamic area at the low voltage by increasing the electrostatic capacity of the floating diffusion area. A CMOS image sensor comprises a photo diode(210), the first floating diffusion area(230a), and the second floating diffusion area(230b). The photo diode converts the light into the electric charge. The first floating diffusion area has the first electric potential corresponding to the amount of the electric charge. The first floating diffusion area relates with the sensitivity of image. The second floating diffusion area has the second electric potential by receiving the electric charge of the first floating diffusion area. The second diffusion floating zone relates with the intensity of illumination of image.


The article covers the problems connected with the system of indicators of productivity and efficiency of medical care in health care as the main criteria of its quality and accessibility. The authors consider four levels of efficiency: federal, subject of federation, medical organization and personal. It is established that at all levels under current legislation on health care, parameters and indicators of productivity and efficiency of medical care are either absent, or presented in a limited list that doesn't let estimate medical care in full quality and accessibility.


The present study intended to analyze calliphorid attraction to traps painted in a variety of colors and the calliphorid constancy index in the Tingua Biological Reserve, Rio de Janeiro state, Brazil. The Diptera were collected monthly in the Reserve, between 2002 and 2005, totaling 24 samplings. Four traps containing sardines as bait were painted olive green, blood red, black, or white and exposed for 48 h at four equidistant points, 50 m from each other. To determine the calliphorid species constancy, the Bodenheirmer constancy index was used throughout the study. To analyze differences in the total abundance between species and in their color selection, an ANCOVA test with a significance level of 5 % and a Tukey post-test were used, considering the categories species and color as cofactors and climatic variables as co-variables (temperature, relative humidity and precipitation), since the samples were collected over two years. 10,444 insects were captured. Of these, 56 % belonged to the Calliphoridae family, totaling 13 species, with the most frequent species being Laneela nigripes (28.5 %), Hemilucilia semidiaphana (17 %), and Mesembrinella sp. (16.4 %). The other species had frequencies lower than 12 %. Nine species were considered constant, two accessories, and two accidental. The data indicated that the most frequent species presented significant differences between themselves concerning abundance over the captured months, however, the Tukey post-test indicated differences only between a few of them. The black trap presented the higher relative calliphorid frequency (27.34 %), followed by green (25 %), red (24.0 %), and white (23.7 %), although the species abundance in the different colored traps did not differ significantly among themselves. Therefore, there was no Calliphorid flies preference for any of the tested colors.


Severe leptospirosis with pulmonary hemorrhage is emerging globally. Measures to control leptospirosis through sanitation depend on accurate case finding and reporting. Rapid death certificate reporting, plus necropsy of persons who died of leptospirosis, facilitates public health intervention and could provide an important tool in assessing the global burden of leptospirosis.


Faithfulness metrics measure how faithfully a visualization displays the ground truth information of the data. For example, neighborhood faithfulness metrics measure how faithfully the geometric neighbors of vertices in a graph drawing represent the ground truth neighbors of vertices in the graph. This paper presents a new dynamic neighborhood change (DNC) faithfulness metric for dynamic graphs to measure how proportional the geometric neighborhood change in dynamic graph drawings is to the ground truth neighborhood change in dynamic graphs. We validate the DNC metrics using deformation experiments, demonstrating that it can accurately measure neighborhood change faithfulness in dynamic graph drawings. We then present extensive comparison experiments to evaluate popular graph drawing algorithms using DNC, to recommend which layout obtains the highest neighborhood change faithfulness on a variety of dynamic graphs.


Knowledge management provides a budding class to decision making that itself rest on the bench of intellectual capital. However, the present study attempts to extract the relationship between intellectual capital and decision making in egovernance systems in Indian public sector. The study identified the moderating effect of knowledge management process on the relationship between intellectual capital and decision making. However, it showed that all what is required is an ideal combination of human, structural or relational capital with that of the various stages of knowledge management process for an effective decision-making. Consequently, the findings of the present study have practical contributions to the government organizations that may serve as a reference for government organization in the implementation of effective KM system for the decisionmaking in their work culture.


A 38-weeks' gestation female whose birthweight was 4,040 g was born to a 17-year-old girl whose pregnancy was complicated by diabetes, fetal intra-abdominal calcifications, and trisomy 21. The infant was delivered by spontaneous vaginal delivery and had Apgar scores of 8 at both 1 and 5 minutes. Immediately after birth, a 5-French umbilical venous line is placed and shortly thereafter, an upper gastrointestinal (UGI) examination documented duodenal stenosis. The infant was taken to surgery, where duodenal stenosis and multiple adhesions consistent with prenatal intestinal perforation were found. The surgeon performed a duodenostomy and appendectomy and placed a triple-lumen polyurethane central venous line (CVL) through the subclavian vein. When the infant left the operating room, 10% glucose was running through the umbilical venous catheter at a maintenance rate. A chest radiograph was ordered to validate the placement of the newly inserted CVL. The surgeon called from the radiology department and informed the pediatric resident that placement was good and to start using the subclavian catheter. At that point, lactated Ringer solution (LRS) was started at a maintenance rate. Testimony was taken from the pediatric resident, neonatologist, and bedside nurse. Their testimony was inconsistent with each other and with the documentation in terms of when and if maintenance fluids were discontinued via the umbilical line and when orders were given and received to discontinue the umbilical catheter .

Four hours later, the infant had an oxygen saturation of 52%. Her blood pressure was 62/17 mm Hg, heart rate was 183 beats/min, and arterial blood gas had the following results: pH of 6.9, Pco2 of 76 mm Hg, Po2 33 mm Hg, and base deficit of −17 mEq/L. The neonatal attending physician ordered a bolus of 40 mL LRS and requested a repeat blood gas assessment in 1 hour. …


Objective To assess smoking, problem drinking, other drug use and gambling in Asian students and New Zealand patients using a multi-item lifestyle screening tool. Methods The setting was three Asian language schools and urban and rural general practices, 2002–2003. Participants (246 Asian students plus 2543 consecutive adult patients of randomly selected general practitioners and practice nurses) completed the screening tool and evaluation form. Results The tool was highly acceptable to all participant groups, with response rates similar for patients from different settings. Significantly more Asian student 'youth' (aged 16–25) than patients expressed the need to reduce their alcohol intake (p<0.001), recreational drug use (p<0.001) and gambling concerns (p<0.001). More Asian students than patients wanted help with the issue of concern, either immediately or at a later date. For gambling, 6.5% wanted assistance (compared with 0.5% 'youth' patients). Some differences were age-related, but comparing Asian student and Auckland patients, both genders had had significantly more drug use and gambling concerns, and male students more concerns about cigarette smoking than their patient counterparts. Conclusions A minority of Asian students appear to have significant lifestyle-related concerns. Gambling treatment centres see predominantly males, indicating females are not accessing necessary care. Implications Some young Asian students arrive with large disposable incomes; sudden access to licensed gambling premises; increased freedom and little parental supervision. We recommend appropriate orientation on arrival with intersectorial agency co-ordination of healthy lifestyle education. Issues around gambling, smoking, alcohol and recreational drug use should be addressed by students' educational institutions with ongoing support and pastoral care.


A new off-lattice Brownian dynamics simulation potential for wormlike micelles in the framework of equilibrium polymerization is proposed. The system reproduces the complete experimentally observed dependence of mean chain length 〈L〉 with concentration φ for uncharged species: a very slow dependence at very low φ, a 〈L〉∝Φ0.5 in the dilute and semidilute regime, and an enormous growth with concentration at high φ. Besides, it is shown that at high φ the longest chains are swollen by the smallest, suggesting a Russian dolls picture of the system.


IRAS observations of the peculiar galaxy Arp 220 = IC 4553 show that it is extremely luminous in the far-infrared with a total luminosity of - 2 X 10^(12) L_☉. The infrared-to-blue luminosity ratio of this galaxy is - 80, which is the largest value of the ratio for galaxies in the UGC catalog, and places it in the range of the
"unidentified" infrared sources recently reported by Houck et al. in the IRAS all-sky survey. Other observations of Arp 220, combined with the luminosity in the infrared, allow either a Seyfert-like or starburst origin for this luminosity.


The interaction of Si, Ti, and Mo atoms with pyrolytic graphite substrates has been studied for evaporated layers of about 100 nm and implanted ions with mean ranges between 2 and 4 nm. In the temperature range from room temperature to 1800 K the thermal diffusion of carbon into the evaporated layers has been studied by Rutherford backscattering spectroscopy while the temperature dependence of the carbide formation has been studied by x‐ray photoelectron spectroscopy. For all three systems stable carbidic phases are predicted by equilibrium phase diagrams. For Ti the formation of TiC is already observed after room temperature implantation, while for Mo annealing to 1200 K is necessary for Mo2C formation. In the case of Si oxygen contamination due to the air transfer after implantation resulted in a mixed SiOxCy phase which only transformed into a SiC phase at temperatures above 900 K, where the oxygen was released. The temperature range of stability of the carbidic layers was found to be correlated to the...


STUDY OBJECTIVE
To determine whether obstructive sleep apnea (OSA) risk is associated with depression and anxiety symptoms in women with polycystic ovary syndrome (PCOS).

METHODS
This is a cross-sectional study of women with PCOS, by the Rotterdam criteria, seen at a single academic center between June 2017 and June 2020. Depression symptoms, anxiety symptoms and OSA risk were assessed with self-administered Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7) and Berlin questionnaires, respectively. Univariate and multivariate logistic regression analyses were used to determine the odds of moderate/severe symptoms of depression (PHQ-9 ≥ 10) and anxiety (GAD-7 ≥ 10) in the high-risk versus low-risk OSA groups. The primary multivariate model adjusted for age, body mass index (BMI), free testosterone and insulin resistance.

RESULTS
Of the 200 participants, the mean age was 28.0 years and 38% screened high-risk for OSA. Women who screened high-risk OSA had over three times the odds of moderate/severe depression (OR 3.19, 95% CI 1.76-5.78, P<0.001) and over two times the odds of having moderate/severe anxiety (OR 2.49, 95% CI 1.34-4.64, P=0.004). These associations were only slightly attenuated in the adjusted models: aOR for moderate/severe depression was 3.06 (95% CI 1.36-6.88, P=0.01) and aOR for moderate/severe anxiety was 2.39 (95% CI 1.03-5.59, P=0.04).

CONCLUSIONS
Among women with PCOS, those at high-risk of OSA experienced elevated depression and anxiety symptoms compared to those at low-risk for OSA, independent of the effects of age, BMI, hyperandrogenism and insulin resistance.


Measurements of the H/sup +/, H/sub 2sup +/, and H/sub 3sup +/ fractions and emittances of a hydrogen beam extracted from an RF-driven multi-cusp source were made using a bending magnet and an electrostatic emittance scanner. The H/sup +/ fraction increased with RF power. Fractions in excess of 90% were obtained. At a given RF power, the H/sup +/ fraction increased with decreasing source pressure and increasing filter rod separation. When the "collar" surrounding the extraction aperture (used for H/sup -/ operation) was removed, the H/sup +/ current increased by a factor of /spl ap/4, without changing the H/sup +/ fraction at a given RF power. With a large filter rod separation, H/sup +/ currents on the order of 100 mA were achieved at /spl ap/20 kW of RF power. Using a modified extractor operating at 35 kV, H/sup +/ currents on the order of 60 mA were obtained with a 90% normalized rms emittance of 0.012 /spl pi/cm-mrad.<<ETX>>


3GPP began standardization of carrier aggregation (CA) in LTE-A Rel. 10 to combine up to five component carriers (CCs) for facilitating wider transmission bandwidth of 100 MHz. Further enhancements followed in Rel. 11 and Rel. 12 to enable features such as aggregation of carriers between time-division duplex (TDD) and frequency-division duplex (FDD) frame structures. In LTE-A Pro Rel. 13, massive CA enhancements were defined to combine more than five CCs with the initial focus on the downlink. While the benefits of CA have been evident, operating an even larger number of downlink carriers results in increased overhead on the uplink as there is a need to send the combined control information for all the CCs. In this article we give an overview of the standardized enhancements, their impact on uplink control information overhead and its transmission, new control channel formats and their link level investigation in 3GPP-defined simulation assumptions.


In this paper, the proposed system has demonstrated three ways of detecting alcohol level in the body of the car driver and prevent car driver from driving the vehicle by turning off the ignition system. It also sends messages to concerned people. In order to detect breath alcohol level MQ-3 sensor is included in this module along with heartbeat sensor which can detect the heart beat rate of driver, facial recognition using webcam & MATLAB and a Wi-Fi module to send a message through the TCP/IP App, a Raspberry pi module to turn off the ignition and an alarm as prevention module. If a driver alcohol intake is more than the prescribed range, set by government the ignition will be made off provided either his heart beat abnormal or the driver is drowsy. In both the cases there will be a message sent to the App and from the App you can send it to family, friend, and well-wisher or nearest cop for the help. The system is developed considering the fact if driver is drunk and he needs a help, his friend can drive the car if he is not drunk. The safety of both the driver and the surroundings are aimed by this system and this aids in minimizing death cases by drunken driving and also burden on the cops.


The work being presented in the present thesis is devoted to the study of duality results for minimax fractional programming problems under exponential (p, r)-invexity assumptions. The chapterwise summary of the thesis is as follows: Chapter 1 is introductory in nature. This chapter includes minimax fractional programming problem, definitions, notations that are used throughout the work and detailed review of minimax fractional programming problems and summary of the thesis has also been discussed. In Chapter 2, we have studied a minimax fractional programming problem involving exponential (p, r)-invex functions [16] and weak, strong and strict converse duality theorems are established under exponential (p, r)−invex assumptions. In Chapter 3, we have reviewed a mixed-type dual problem with exponential (p, r)-invexity considered by Lai and Ho [12] and proved the duality theorems related to the primal problem and the mixed-type dual problem. In Chapter 4, motivated by Lai and Ho [10], we have established nonparametric necessary and sufficient optimality conditions for a minimax fractional programming problem with B(p, r)-invexity. These optimality conditions are deduced to two parameter-free type dual models: Mond-Weir type dual and Wolfe type dual problems. On these duality types, we have established the duality theorems under exponential B-(p, r) invexities including weak duality, strong duality and strict converse duality theorems.


On October 31, 2013, the US Food and Drug Administration (FDA) suspended marketing and sales of the BCR-ABL tyrosine kinase inhibitor ponatinib (Iclusig, Ariad Pharmaceuticals). Just 7 weeks later, on December 20, 2013, the FDA partially reversed that decision, permitting use of the drug under a narrower indication. Ponatinib was the sixth drug approved for the treatment of chronic myeloid leukemia (CML) or Philadelphia chromosome–positive acute lymphoblastic leukemia and indicated for patients refractory or intolerant to prior tyrosine kinase inhibitor (TKI) therapy (Table).


Abstract The popularity of green innovation has dramatically increased in the recent times because of the potential benefits attached with it. Therefore, in order to make the technology more affordable, green innovation is the key to enhancing the affordability factor. On the other hand, in order to safeguard the environment, the role of media is one of fundamental importance. In contrast, energy consumption is often regarded as a key indicator of economic prosperity, mostly at the cost of the environment. Hence, the present study attempts to explore the asymmetric effect of the film and drama industry, energy efficiency, and economic growth on green innovation, with the help of the latest quantile autoregressive distributed lag (QARDL) method for the period 2000Q1 to 2019Q4. The results have reported a positive and significant association of the Film and Drama Industry, Energy Efficiency, and economic growth on the quantiles of Green Innovation. Based on the findings, it is recommended that there is a dire need to develop content that promotes the green innovation, whereas, more investments are to be sought after, so as to enhance the level of energy efficiency.


The Mossbauer effect has been used to study the magnetic properties of pseudobinary (Er,Gd)Fe3 compounds. The spectra show that the spin-reorientation temperature, Tr, decreases with increasing Gd concentration. This decrease is explained by the concentration dependence of the average crystal field anisotropy at the (Er, Gd) sites. A simple single-ion model for the free energy was used to describe the magnetocrystalline anisotropy. The model adequately describes the concentration dependence of the reorientation temperature.


AbstractEffects of propagation and interference of spin waves in an eight-port magnonic structure in the form of a 2 × 2 array of microwaveguides based on yttrium-iron garnet films with microantennas placed at the waveguide ends are studied experimentally and numerically. It is shown that conditions for a constructive and destructive interference of spin waves, which is necessary for creating spin-wave logic devices, can be implemented at output transducers by changing the phase of input signals.


OBJECTIVE To study the expression of myosin light chain kinase(MLCK) in endothelial cell regulated by the melatonin through the pathway of ERK/MAPK in atherosclerosis(AS) model rabbit. METHODS The model rabbit of AS was established and the dynamic variability of the lipids in the serum of model rabbits was analyzed. The MLCK activity of artery tissue of model rabbits was measured by the method of γ-32P-ATP incorporated.The expression of MLCK in the endothelial cell was detected by immunohistochemistry and western blot, meanwhile, the phosphorylation of ERK in the endothelial cell was also detected by western blot. The change of morphology of artery wall in model rabbits was examined according to the HE stain. RESULTS The AS rabbit model was established successfully. After being fed with the high cholesterol (Cho) for 4,8,12 weeks, compared with the normal control, the related biochemistry quotas was increased obviously in the serum (P0.05),the MLCK activity of artery tissue of model rabbits was increased gradually(P0.05),the expression of MLCK and the phosphorylation of ERK in the artery tissue were raised gradually. At the same time,the HE staining indicated the increase of foam cells products. When melatonin(MLT) was added into the high Cho food,the activity of MLCK,the permeability of arterial wall,the expression of MLCK and the phosphorylation of ERK in artery tissue were decreased. The aortic tunica intima symptom seem to be reliefed. CONCLUSION MLT may relief the pathological changes of plaque in the AS model rabbit through the pathway of ERK/MAPK to down regulate the activity of MLCK in endothelial cell.


The small-signal stability of the LCC-HVDC system connected to the weak AC grid is of great concern. This paper derives the SISO model of the LCC inverter station. On this basis, the influence mechanism of AC system strength on system stability is studied via the Bode stability criterion, and the coupling interaction between different control loops is quantitatively evaluated. Results reveal that, as the AC grid becomes weaker, the system stability margin is diminished characterized by the larger phase lag in the phase-frequency response. Also, the interaction between DC voltage controller (DVC) and phase locked loop (PLL) control loops is intensified. Then, a derivative-feedback based compensation (DFC) control is presented to improve the LCC system stability under the weak AC grid condition. Theoretical analysis and simulation results indicate that the presented DFC control can effectively improve the stability and dynamic performances of the LCC system, which allows the system to operate stably even connected to the extremely weak AC grid.


The present work of research is elaborated with the purpose of Determining how the
social marketing strategy - inbound marketing impacts on the level of sales of the
company CISESA Movistar - Chepen Branch: 2017. It has a descriptive and
correlational type as a research design. La muestra estuvo conformed by 377 clients
of CICESA Branch Chepen. For data collection, a survey was used with a 24-item
survey instrument to study both variables, later applying computer tools for tabulation
and table-making, and for statistical validation using the correlation coefficient R² and
la a lot of hypotheses Chi². According to the results, it is concluded that: The social
marketing strategy - inbound marketing has a positive impact on the sales level of the
company CISESA Movistar - Chepen Branch: 2017, generating an increase of 7% of
clients served and 13%. in volume of sales.


Medication errors have been increasingly recognized as a major cause of iatrogenic illness and system improvements have been the focus of prevention efforts. Critically ill patients are particularly vulnerable to injury resulting from medication error because of the severity of illness, need for high risk medications with a narrow therapeutic index and frequent use of intravenous infusions. According to healthcare and health industry leaders, using information technology enhances patient safety by preventing medical errors, assessment errors and surveillance system with rapid response and reduces the risk of harm created after the fact. Health information technology has been identified as a method to reduce medication errors as well as improve the efficiency and quality of care; however, few studies regarding the impact of health information technology have focused on patients in the intensive care unit. Computerized physician order entry and clinical decision support systems can play a crucial role in decreasing errors in the ordering stage of the medication use process through improving the completeness and legibility of orders, alerting physicians to medication allergies and drug interactions and providing a means for standardization of practice. Electronic surveillance, reminders and alerts identify patients susceptible to an adverse event, communicate critical changes in a patient's condition, and facilitate timely and appropriate treatment. In this paper, medical errors are investigated, the role of information technology in reducing and preventing medical errors is investigated, and recommendations | Volume – 2 | Issue – 4 | May-Jun 6470 | www.ijtsrd.com | Volume Journal of Trend in Scientific and Development (IJTSRD) International Open Access Journal ion errors and increase patient Mrs. Ruchi B Vyas Dr. Dayaram Patel Pharmacy College, Bardoli, Surat, Gujarat Mr. Diwakar Dadarwal Sanjeevni College of Pharmaceutical Sciences Rajota, Khteri, Rajasthan


This paper presentsa web application designed to support the teachingof basic3D computer graphicsconcepts. Thistool isaimed at introductory courses of computer graphics in the context of engineering studies. Through the web platform, theteacher configures and proposes interactively exercises related to the main 3D concepts studied in this kind of course. Thestudent accesses the exercises through the web application and configures a solution, also visually and interactively, usingthe tool. Then the teacher can visualize the solutions given by the students and compare them with the right solution in a 3Denvironment. In addition, the platform provides an automatic pre-assessment of the exercises, which can be adopted by theprofessor or modified based on the visual revision. The tool has already been used in the classroom and it was assessed byanalyzing both the experience of use and the relation between students' marks and the number of interactive exercisesperformed. The results obtained suggest that using the application is a positive factor to obtain better marks, regardless thestudents' ability or competence. The application is available via the link: http://www4.ujaen.es/~demiras/cgex.


This study aims to develop a rational evaluation system which consists of the selection of evaluation items and the estimation of its weight for the Enhancement Program of the Quality of Life for Farmers and Fishermen and Rural Development. This system has two hierarchical steps. The first step shows the evaluation goals which are relevance, efficiency and effectiveness of the program. The second step stands for the evaluation items which have 11 sub-items such as necessity and externalization for the program, rationality of procedures, feedback and monitoring system, budgetary allocations, information activities, impacts on the program, achievements of the goals and so on. A tentative evaluation system was proposed by brainstorming and Delphi method of expert-group. Weighting values of evaluation items were calculated through pair-comparison works of expert group using stepwise matrix sheets by AHP(Analytic Hierarchy Process).


Correspondence to Dr Yibeltal Assefa; y. alemu@ uq. edu. au © Author(s) (or their employer(s)) 2021. Reuse permitted under CC BYNC. No commercial reuse. See rights and permissions. Published by BMJ. THE COVID-19 PANDEMIC: A REMINDER FOR A STRONG GLOBAL HEALTH SYSTEM The COVID-19 pandemic is a timely reminder of the nature and impact of global health threats that could become Public Health Emergency of International Concern (PHEIC). The virus has spread quickly to all countries (although with variable epidemiological patterns), and has overwhelmed even some of the most advanced health systems. As of 12 April 2021, the pandemic has caused more than 136 million cases and 2.93 million deaths. But beyond morbidity and mortality, it affects the whole of society and government, and causes serious socioeconomic loss. With the emergence and spread of new variants of the virus, it is highly likely that the virus will be circulating and staying with us for the foreseeable future. The longer and the more severe the pandemic, the greater are the social and economic disruptions and the political challenges. The COVID-19 pandemic spread throughout the world due to inadequate preparedness for global health security (GHS). The spread and consequence of the virus is intensified by gaps in the implementation of the programmes in the third Sustainable Development Goal, including universal health coverage (UHC), and tension between UHC and GHS. 13 The pandemic demonstrates that health security is not only a national but also a regional and global common good. It substantiates that the world urgently needs a strong global health system, including global, regional and national actors with collective responsibility and mutual accountability. It also highlights the need for robust systems to respond more effectively to the inevitable future global health challenges. A strong global health system is vital to tackle current and future PHEIC. WHY SHOULD COUNTRIES DO MORE TOWARDS A STRONG GLOBAL HEALTH SYSTEM? Countries have several incentives to plan and act locally, regionally and globally towards a strong global health system that can prevent, detect and respond to PHEIC. Pandemics not only cost lives but also pose some of the greatest risks to the global economy and security. As the world's population becomes more mobile and interdependent, and with biodiversity reduction and ecological degradation, global health threats increase and traditional defences at national borders cannot protect people against the invasion of a disease or vector. We argue that countries have at least three foreign policy imperatives why they should cooperate more intensively on global health; namely for security, economic and moral Summary box


The main objective of a seeding machine is to put seeds at a desired depth and spacing within the row. Seed spacing uniformity is one of the most important criteria in evaluating planter performance. Therefore, the objective of this research work was to develop an opt-electronic monitoring system for assessment of a mechanical planter seed metering unit performance. The developed system was used to monitor seed flow and to measure seed spacing from the metering system of the row crop planter. The developed system comprised of an optoelectronic sensor for seeds detection, a rotary encoder for forward speed and seed position measurement, amplifiers for adjusting sensors signals, a microcontroller for synchronizing sensors signals, and a PC for operating the program and displaying process. The developed system has been successfully tested on chickpeas seeds at two operating speeds (1.3 m/s and 1.9 m/s). Both numbers and locations of the dropped seeds were assessed. The results indicated that the developed system can be accurately used to detect seeds flow from the metering system with overall system errors of ±4% and ± 10% for speeds of 1.3m/s and 1.9m/s, respectively, compared to manual measurements. Further extensive testing on different crops under actual field conditions are highly recommended to ensure reliability of the developed system.


The Naval Sea Systems Command (NAVSEA) is developing a framework for providing a total and integrated diagnostic capability for shipboard systems. This framework will consist of policies, standards, guides, and generic diagnostic software packages. A major part of this framework is the Navy Integrated Diagnostic Support System (IDSS). The IDSS is a research and development program to demonstrate the feasibility of an integrated approach to diagnostics. An equally important facet of IDSS is the development of generic software packages to support the ID process. The IDSS supports hardware design through its weapon system testability analyzer tool and diagnostic procedure development through its adaptive diagnostic authoring tool. In the field, a third tool, the adaptive diagnostic subsystem, uses the diagnostic data from the first two tools to fault-isolate system problems. A fourth tool, the feedback analyzer, collects and analyzes field history data and recommends corrective action.<<ETX>>


Objective To explore the feasibility of myomectomy in cesarean section.Methods The clinical data of pregnant women with uterine fibroids(observation group)who underwent myomectomy between January 2006 and December 2011 were retrospectively analyzed.Fifty-two patients who underwent cesarean section were selected as control group.The operative time,blood loss,postoperative passage of flatus,etc in two groups were comparatively analyzed.Results The operation time of the observation group was significantly higher than in the control group(t=3.283,P=0.001)the difference was statistically significant.The rest of the indicators were no difference between the two groups(t2.578,P0.05).Conclusion Depending on the type of fibroids,the timely selection of appropriate culling program.The myomectomy in cesarean section is feasible and safe.


Collisions are a serious threat to ship's safety and despite the existence of codified rules and obligatory COLREG course for the seafarers, the number of maritime accidents is still great. Noticing this we have decided to use group model building to extract the knowledge about the process of collision avoidance from our group of experts. As a result, we obtained 18 factors which we have divided into 4 categories in order of importance. After reviewing the results we have noticed that the experts focused on superficial and theoretical aspects of collision avoidance. Therefore we have concluded that their knowledge despite our initial assumptions was insufficient to thoroughly revise this topic. However, we have also recognized some patterns that would suggest that the current rules could be improved. Our goal is to cause a discussion that will, hopefully, result in changes in education, laws, or both.


Human vitamin D requirement is supplied by two major sources: D2 (ergocalciferol) and D3 (cholecaciferol). Vitamin D3 is synthesized in skin via sun exposure and ultraviolet irradiation of the epidermis and vitamin D2 comes from food stuffs, especially beef liver, cheese, egg yolk and fatty fish. For longer halflife of 25hydroxy vitamin D, compared to 125 (OH)2 vitamin D, serum 25-OH-vitamin D has become the standard laboratory test to define vitamin D status. A serum 25(OH) vitamin D levels of < 20 ng/ ml has been considered as vitamin D deficiency, and values between 21-29 ng/ml as insufficiency. Vitamin D is sufficient if it is > 30 ng/ml and in toxic levels if > 150ng/ml.


Vehicular ad hoc networks (VANETs) are emerging as a novel paradigm for safety services, supporting real-time applications (e.g., video-streaming, Internet browsing, online gaming, etc.). However, maintaining ubiquitous connectivity remains a challenge due to both high vehicle speed, and non-homogeneous nature of the network access infrastructure. Getting access to the network infrastructure must be controlled and only authorized users should be able to use it. However, the authentication process incurs in a not-negligible delay which can result in packet losses and other issues during handoffs. Hence, a fast and secure handoff scheme is essential. Although some solutions have been given in IEEE 802.11i and 802.11r standards, the handoff latency is still above 50 ms. Other protocols such as CAPWAP and HOKEY include support for fast handoff but have not been evaluated in a vehicular network. In this article, we analyze the security properties and performance of current proposals. Finally, simulations are conducted to date the effectiveness of the handoffs schemes.


Developing countries abounded in various resources of significant importance for rural populations. The o b- jective of this work is to describe and analyze the use of wild edible plants of Guiziga people. For this, 180 peasants were interviewed to determine the use frequencies of wild e dible plants. Wild edible plants are identified by their scientific and vernacular names, parts used and modes of preparation and consumption. The Guiziga people use 24 plants as sources of food which are consumed in 37 different forms. Four species pr oducing six forms of food are included here for the first time among Guiziga people. However, only a few wild edible plants are used frequently while others are occasionally or not at all. An intercultural comparison between Guiziga and four territorial neighbors reveals that it exists a great simila r- ity between Guiziga people and their neighbors on wild edible plants despite the fact that they have a different cultural basis. The close cultural habit would significantly affect Guiziga people ethnobotany. This article is a first contribution t o an understanding of ethnobotany of Guiziga people and to a comparison of inter -ethnic relations concerning their r e- sources in wild edible plants .


By the recent development of laser technology, the laser irradiation intensity can be well above 1018 W/cm2. The simulation of ultra intense laser interaction with solid density plasmas are presented in this paper. Fast ion and electron emission, neutron yield due to D-D reaction and absorption of laser energy are discussed.


An emerging body of evidence has promoted the understanding of the role of microRNAs (miRNAs) in tumorigenesis and progression, but the mediating function of miRNAs in nasopharyngeal carcinoma (NPC) development remains poorly elucidated. In this study, miR‐449b‐3p was downregulated in NPC specimens (P < .001) and cells (P < .05). Cytological and animal experiments provided evidence that miR‐449b‐3p inhibited NPC metastasis in vitro and in vivo. Disintegrin and metalloproteinase 17 (ADAM17) was revealed as a direct target of miR‐449b‐3p. Rescue experiments suggested that the downregulation of ADAM17 in the miR‐449b‐3p knockdown cells partially reversed the inhibition of cell invasion and migration. Luciferase reporter assay, chromatin immunoprecipitation assay, and Western blot analysis showed that ADAM17 could suppress the promoter activity and expression of miR‐449b‐3p by inducing NF‐κB transcriptional activity. In conclusion, our study provided new insights into the underlying mechanism of the invasion and metastasis of NPC. The novel miR‐449b‐3p/ADAM17/NF‐κB feedback loop could be a target for the clinical treatment of NPC.


Under a dynamic spectrum access paradigm, a set of L spectrum bands licensed to primary users provide opportunities for an unlicensed secondary user to gain access to spectrum left idle by a primary user. We model the received noisy signal measurements on each band as a continuous-time Markov chain observed through a discrete-time Gaussian channel. Based on this model, we develop a scheme for estimating the parameters of the subset of $L^{*}\lt L$ bands that offer the "best" opportunities for dynamic spectrum access in the sense of largest mean idle periods. Our approach consists of a Markov modulated Gaussian process model, an associated expectation-maximization algorithm, and a computing budget allocation scheme for allocating sensing effort across the spectrum bands over a sequence of observation intervals. The sensing effort allocation scheme maximizes the probability that the $L^{*}$ best bands will be determined from their parameter estimates obtained in the next observation interval. Simulation results are presented to demonstrate the performance of the proposed scheme.1


The global electric vehicle uptake and the increasing electrification of final energy consumption could bring grid management issues to the distribution system in a near future. Demand response programs are seen as a direct solution through the aggregation of distributed flexibility resources, expecting electric vehicles to be one of the main flexibility sources. However, the charging demand depends on the variability of daily drivers' behaviour, and calculate the aggregated flexibility potential from forecasted individual sessions may result in a highly inefficient process and uncertain result. Therefore, to reduce this uncertainty, this work proposes a methodology to discover distinct user profiles with a model-based clustering method followed by the aggregation of the clusters into daily user profiles. The clustering method uses only the two basic connection variables available for any charging infrastructure: the connection start time and the duration of the connection. The method has been tested with data from the public charging infrastructure of the city of Arnhem, in The Netherlands. The clustering process has resulted in 45 different clusters aggregated into 7 user profiles, some of them with very low variability and therefore clearly useful to consider in flexibility programs.


Based on comprehensive consideration of the basic design concept for ball bearings and rotary supporting,combining with GL design specification and ISO standard of wind turbine industry,the related calculation methods is reasonably used based on real loading conditions under yaw bearings coordinate system of wind turbines.The concrete process is accurately combed for calculation of life and carrying capacity of yaw bearings.The difference is compared between the different standards and specifications.The results show that despite the calculation results of various methods have differences,but does not affect the basic judgment for yaw bearings,so the simple algorithm is able to be used to rapidly check and analyze yaw bearings.


Cosio-Lima LM, Schuler PB, Reynolds KL, Taylor L, Kellog G, Cerney J, Hodges T, LeBlanc PA. The effects of age and type-2 diabetes on the release of interleukin (IL)-6, IL-10, TNF-alpha, and cortisol in response to acute exercise. JEPonline 2008;11(3):33-41. The immune response to exercise results in the release of inflammatory markers. This study examined the effects of age and type-2 diabetes on cytokine response following an acute bout of exercise. Five older type-2 diabetics (OD) (mean age 82±3 years), 5 non-diabetic (79±6 years) older adults (OND), and 5 young healthy (YH) (26±3years) control subjects were studied before and following a sub-maximal incremental treadmill test. Venous blood samples were collected immediately preand 5 minutes post-exercise, and plasma was analyzed for interleukin (IL)-6, IL -10, tumor necrosis factor-a (TNF-a), C–reactive protein (CRP), and cortisol levels . Cortisol levels were significantly elevated postexercise (p<0.05) for all participants suggesting a sufficient exercise stimulus (>60%HRR). A significant main effect for group was found for IL-6 (p<0.05) with post-hoc tests suggesting significantly higher levels in the older diabetic group (OD) compared to the young controls (YH). No significant group by time interaction was found for any of the variables studied. Present study findings suggest that age, rather than the presence of diabetes, affected resting plasma IL -6 levels. Furthermore, neither age nor diabetes influenced cytokine responses to an acute bout of exercise.


The direction of arriving (DOA) estimation algorithms used in TD-SCDMA system to realize DOA detection would result in a large number of mathematical operations. Meanwhile, the number of DOA detection would be restricted by the number of array elements of a smart antenna. To solve this problem, a new method for DOA detection based on the orthogonal mid-amble sequence would be presented in this paper, which can be employed in system with beam-forming by the method of amplitude weighting of base-band signal (AWB). The directional transmitting of smart antenna can be achieved by this method without any method of conventional frequency spectrum search or DOA estimation algorithms. The parameters of DOA for mobile station could be detected by the new method, which could be used in a system with directional transmitting directly. The working principle of this new DOA estimation method would be introduced in this paper as well as its proving.


ABSTRACT My commentary begins with consideration of the methodology used, discussing this in relation to two key facets of the study findings. I compare Asbjørnslett and Bekken's findings to those of my own study, which revealed the presence of particular skills used by community members that enable one another to participate. I situate the theme of people's inclusive actions to current understandings about the notion of altruism. I conclude with reference to Dr Peter Rosenbaum's reflections on future research directions for learning more about ways to improve people's attitudes to those with disabilities.


This paper analyzes the causes of incorrect operation accidents,expounds the main expressions of illegal behaviors,and puts forward some dangerous points existing in pour switching operation standardization program and some precautionary measures.


in the uprooting by oppressive rulers of entire communities and the transportation of millions of human beings regardless of their own reactions, their traditions, and their environment. In some respects regrouping was perhaps desirable, but the means by which this supremely difficult task was undertaken undermined all possibility of a fair and permanent settlement. Neither have the democracies been always sufficiently alive to the importance of the methods by which reforms


Listener expectations may have significant effects on spoken word recognition, modulating word similarity effects from the lexicon. This study investigates the effect of blocking by lexical status on the recognition of word and nonsense syllables in noise. 240 phonemically matched word and nonsense CVC syllables [Boothroyd and Nittrouer, J. Acoust. Soc. Am. 84, 101–108 (1988)] were presented to listeners at different S/N ratios for identification. In the mixed condition, listeners were presented with blocks containing both words and nonwords, while listeners in the blocked condition were presented with the trials in blocks containing either words or nonwords. The targets were presented in isolation with 50 ms of preceding and following noise. Preliminary results indicate no effect of blocking on accuracy for either word or nonsense syllables; results from neighborhood density analyses will be presented. Consistent with previous studies, a j‐factor analysis indicates that words are perceived as containing ...


Abstract : Discussed are dependences of signal-to-noise ratio of photoelectronic multipliers working in the flying spot system from electrical, light and thermal working regimes. Investigated is the influence of vacuum on the signal-to-noise ratio of photoelectronic multiplier. Given are recommendations for exploitation conditions of photoelectronic multiplier in the flying spot system to assure its optimum signal-to-noise ratio.


The invention belongs to the technical field of traffic surveillance and video processing and particularly discloses a video-based method for rapidly detecting transit vehicles. Based on a background difference method, a gradient frame difference method and a frame difference method, the method can simultaneously eliminate the daytime shadows, respiration effect, night headlamp ground-reflected light and other impacts, accurately detect the position of a moving object and judge the lane, where the vehicle is located. According to test results, the method of the invention can overcome the defect that the calculation load is higher in the conventional method and meet the requirement for the real-time performance in the video vehicle detection carried out by an electronic police; and the method is capable of accurately detecting the vehicles in the sight, and has better robustness against the interference, such as light changes, shadows and the like.


Recent interpretations of policy developments across Europe have suggested a potential tension between multiculturalism and national identity. This article examines how this tension has been understood in British political debate by analysing, as a proxy, debates from the House of Lords. These debates show that four competing frames exist on the relationship between multiculturalism and national identity. These frames offer rival perspectives on the issues surrounding multiculturalism and national identity; they present different problems and solutions. Moreover, the article shows how these frames start from different interpretations of the social reality they are responding to. It concludes by questioning the pursuit of consensus on these matters.


The goal of the System Dynamics Model (ESCOT) is to describe a path towards a sustainable transport system in Germany and to assess its economic impacts. ESCOT was developed within the environmentally sustainable transport (EST) project of the OECD that was designed to consider the ecological and technical aspects of a transition towards sustainable transportation. ESCOT comprises five models: the macroeconomic, the transport, the regional economic, the environmental and the policy model. An integrated Input-Output-Table for the German economy forms the backbone of the economic assessment. The Input-Output-Table is calculated endogenously by macroeconomic variables mostly from the demand side. It feeds back to other macroeconomic indicators in the next time period. The economic assessment for environmentally sustainable scenarios show that the departure from car and road freight oriented transport policy is far from leading to an economic breakdown. With an expansion of the time period for the transition the authors derived even more encouraging results. For the economic assessment it is important that ESCOT considers not only first round effects but also secondary effects. This ability makes ESCOT to a powerful instrument for the assessment of such large ecological changes.


BACKGROUND
Colorectal cancer (CRC) is the third most commonly diagnosed cancer Worldwide. Currently, colonoscopy remains the gold standard diagnostic test for CRC detection. Nonetheless, this technique is invasive and expensive. Remarkable ongoing strategies are focusing on development affordable methods to diagnosis at earlier stages and surveille CRC. The introduction of suitable noninvasive, sensitive and specified diagnostic tests for early CRC detection by employing biomarker analysis seems to be a fundamental need to reduce the numbers of unnecessary colonoscopies. In this Review, we provide an overview of single- and multi-panel biomarkers (Genomic markers, transcriptome markers, proteomic markers, inflammatory markers and microbiome markers) encompassing noninvasive tests in blood and stool for early CRC detection.

METHODS
A bibliographic search using PubMed/Medline, Web of Science and EBSCOhost databases was performed to find relevant published studies over the last 6 years. Forty-three pertinent studies were included in this review.

RESULTS
The primary outcome highlights the sensitivity and specificity of single diagnostic biomarkers studied in blood or stool. The secondary outcome reveals the sensitivity and specificity of panel -biomarkers (combinations) in blood or stool. While some markers show better performance, other are not suitable for screening purposes.

CONCLUSION
It remains to adjust experimental and analytical tests that can interfere à robust results to replace or supplement those currently markers in use. Even so, robust verification and validation with large clinical cohorts are needed to successful noninvasive tests that can fulfill the role of colonoscopy.


Purpose

The purpose of this paper is to identify and analyse the typology of employee branding in an airline company using fuzzy c-means (FCM) clustering to improve the quality of employee brand (EB).

Design/methodology/approach

Data were collected from employees of Air India, Chennai division, using a questionnaire and analysed using FCM to find the optimum cluster number. The nature of each cluster was analysed to know its type.

Findings

The results prove the presence of four types of EB, namely, all-stars, injured reserves, rookies and strike-out kings in the aviation company. It is proven that employees in all-star have high level of knowledge of the desired brand (KDB) and psychological contract (PC), those in injured reserves have high KDB and low PC, rookies have low KDB and high PC and strike-out kings have low KDB and PC.

Research limitations/implications

The results of this study are limited to the Air India employees. This study contributes to employee branding by empirically substantiating the proposed typology using FCM. It proposes the need to analyse organisations individually before comparisons.

Practical implications

The management must focus on the quality of training and development programmes to enhance the position of rookies and strike-out kings. It must also receive regular feedback from injured reserves and strike-out kings to evaluate their perception of PC.

Originality/value

This is the first paper to empirically prove the typology of employee branding and to implement FCM in clustering employees for enhancing the EB's quality.


The Computer Technology Encyclopedia is a handy reference for students and professionals. Going beyond basic definitions, this comprehensive reference provides descriptions of computer technology terms, as well as including numerous tables, photos and illustrations.


Since the emergence of its video industry in the 1990s, Nigeria has pioneered an innovative and highly successful model of film production and distribution. Lagos is now home to the fastest-growing film industry in the world, which releases well over 1000 titles a year without assistance from the government, NGOs or international film festivals. This article analyses the rise of 'Nollywood' through the lens of current debates in creative industries research. The Nigerian video economy offers compelling evidence of the role of informal markets in creating efficient and economically sustainable media industries. Its success also has implications for debates around copyright and media piracy. I conclude that reading Nigerian video as an informal creative industry can be a useful way to rematerialize media studies in the overdeveloped world.


Cultural heritage documents are often subject to digitization processes resulting in image material, even for textual contents. It is therefore common, in collections of valuable documents, to have descriptive information generated by the institutions, along with digitized images, transcriptions created by scholars, translations and even miscellaneous annotations. To offer a faceted access to the collection it is necessary to explore these diverse materials, integrate them according to a model that accounts for both metadata and the content and provide a comprehensive retrieval environment. In this work we have applied the MetaMedia multimedia database framework to a collection of ancient documents, processed the documents in their descriptive, textual, and image content and produced a browsing and searching system. The main challenges are the integrated management of metadata and content, the indexing of the image content, and the design of the browsing and searching interface where various views on the data are kept together.


This paper studies the adsorbing behavior of copper (Ⅱ) on natural iron (hydr) oxide minerals, and the characteristics are summarized as follows: ① Different minerals clearly have different adsorbing abilities. To the same kind of mineral, the kinds and contents of impurities are the main factors affecting adsorbing ability, and the crystal habit affects its adsorbing ability slightly. ② Effect of mineral size on adsorbing ability changes irregularly when the si ze is larger than 140 mesh. ③ pH affects adsorbing ability dramatically. ④ T he adsorbed amount is positively correlated with the initial concentration of co pper (Ⅱ). ⑤ The adsorbing behavior of copper (Ⅱ) on natural iron (hydr)oxid e minerals is in apparent agreement with Freundlich and Temkin iso temperature adsorption.


This article introduces the guideline and aim in talents training in the construction of electrical engineering and automation majors and raises the principle in setting the courses to "strengthen the basis,reinforce practical teaching, stress majors backbone, widen the major'sphere'. It also emphasize practice and pays attention to the cultivation of creating training. It can be adapted to the development of science , culture, society in the 21th century,then satisfy the requirement of advanced special talents.


The main features of understanding "philosophy for children" as a form of modern philosophical practice in various national and cultural traditions are considered. The specificity of international Olympiads in philosophy in real and virtual areas is revealed. The project "Philosophy as a way of developing of moral consciousness and a culture of dialogue between schoolchildren in the educational systems of Russia and Belarus" is presented.


Using a dynamic model of a rear-suspension mountain bicycle, numerical methods are employed to optimize the geometric variables associated with the suspension design. In particular, a genetic algorithm is used to minimize the maximum value of the frame's rotation, in order to minimize the chain–suspension interactions felt by a rider. Two sets of constraint equations are included in the optimization problem. The first set constrains the wheelbase to be constant for all designs, thereby ensuring equivalent handling properties between designs. The second set is required to avoid infeasible designs associated with a collapsed suspension. Results using four geometric parameters as design variables are in good agreement with those obtained using a more complex dynamic model, and with those obtained experimentally. Our optimal design is manufacturable, since the locations of pivots and suspension members are such that no interference will occur between moving parts.


Inthispaperwestudynonlinearcontrolsystemswithmultipledelayson controls and states. To obtain asymptotic stability, we impose Holder-type assump- tions on the perturbing function, and show a Gronwall-type inequality for dierence equations with delay. We prove that a nonlinear control system can be stabilized if its linear control system can be stabilized. Some examples are included in the last part of this paper.


Abstract Over the past five years the Dissenting Academies Project, initiated by Dr Williams's Library and Queens College,London, has gathered information about them for the period 1660-1860. This is now on-line at www.english.qmul.ac.uk/drwilliams/academies.html. The information about the Academies, their staff, students and libraries is used to shed new light on Bristol Baptist Academy President, Revd Dr Caleb Evans.


Advancement in nanoscience and biotechnology of bone materials and cement has been increasing over the past several decades. The combination of biomaterials with trace elements for bone cement has verified their better mechanical strength and biocompatibility response. Also, the ionic replacement has affected the chemical, physical and biological properties of the substance. Pyrophosphate has supported better absorption of calcium phosphates (CaPs) and bone formation. Bone cement is the ionomer of an important material in tooth repair application used in the tooth filling, tooth cover, and to fix adhesions of the tooth and crown. Nanoparticle additives (magnesium oxide (MgO), hydroxyapatite (HA), chitosan (CH), barium sulfate and silica) and alternate monomers can be effective with Polymethyl methacrylate (PMMA) granules and methyl methacrylate monomers (MMAs) to decrease the isothermal temperature. These materials can be used for the growth and development of bone cements. This paper aims to demonstrate a general and different view of the applications of CaP, PMMA, glass ionomer and bone repair cements in various methods under different experiments procedure.


that metatextuality is not obvious in this novel but thinks himself capable, in an ironic reading of the book, of "rendering it manifest" through sorcery (131). Motte also reviews Echenoz, the most accomplished contemporary French writer, in whose novel, Un An (1997), the critic sees the narrative discourse shaping itself on the protagonist's adventures: "As Victoire becomes more and more impoverished, so too does her story, which Echenoz strips of description, interpretation, and commentary" (141). The critic reads Christian Oster's Le Pique-nique (1997) as a mise-en-abîme of the novelist's work in general. He argues that Jean-Philippe Toussaint's La Télévision (1997), with its reflections about writing and the struggle with artistic inspiration, is a novel about the destiny of literature as a cultural manifestation, because "television competes directly with literature in the cultural marketplace" (181). Like La Nébuluese du crabe, Jacques Jouet's La Montagne R (1996), with its central metaphor of the novel as "construction site," and Lydie Salvayre's La Conférence de Cintegabelle (1999), with its questioning of novelistic practices, are the most obviously "metatextual" books discussed by Motte. To use his own epithet, Motte concludes with a bland comment on the necessity of dialogue between reader and writer which sets the conditions of possibility for the survival of the novel as a cultural form (218). What worries me most in this book is that Motte uses the specular quality of a text as an axiological measure for the contemporary French novel. Fewer books would have given Motte more space for a closer reading and for a better argument of gathering them under a single essay. Fevronia Novac, Social Sciences and Humanities Research Council of Canada, Ottawa


Objective To study the influence of tetramethylpyrazine(TMP) on experimental acute pancreatitis model(AP) and investigate the acting machanism of TMP on AP.Methods Acute edematous pancreatitis(AEP) were induced by bombesin(ip,40 μg/kg),pancreatic acinar cell apoptosis and expression of Bax gene were tested respectively by means of triphosphate-biotin nick-end labeling(TUNEL) and immunohistochemical method.Meanwhile,levels of serum IL-6,TNF-α,CRP,AMY and pancreatic histomorphology were observed.Results TMP could markedly inhibit experession of serum IL-6,TNF-α and CRP,regulate the expression of Bax gene up and induce AEP cell apoptosis.Conclusion TMP could treat AP,the acting mechanism is related to down-regulation of IL-6,TNF-α,CRP,up-regulation of Bax gene expression and promotion of pancreatic acinar cell apoptosis.


The Monte Carlo Technique has been applied to the calculation of tissue air ratios for a range of irradiation conditions relevant to diagnostic radiology. In order to make a direct comparison with the previously published data, measurements have been carried out at similar X-ray beam qualities and field sizes. An excellent agreement has been reached between our Monte Carlo calculations and experimental results as well as with the reported values. Since the Monte Carlo Technique eliminates the instrumental problems, it can be used for the derivation of TAR values relevant to diagnostic radiology with an uncertainly of less than 10%.


We have achieved the nearly perfect transmission over 90% of random arrays that can be thought of as merely collective system of single rectangular holes with various length-to-width ratios and slits, using terahertz time domain spectroscopy. It is found that the terahertz transparency by the enhanced transmission can be experimentally realized even in the areal coverage less than 12% at the fundamental shape resonance, provided that the shape is strongly asymmetric.


In this paper, we study a class of down-up algebras $\A$ defined over a polynomial base ring $\K[t_{1}, \cdots, t_{n}]$ and establish several analogous results. We first construct a $\K-$basis for the algebra $\A$. As a result, we prove that the Gelfand-Kirillov dimension of $\A$ is $n+3$ and completely determine the center of $\A$ when $char\K=0$. Then, we prove that the algebra $\A$ is a noetherian domain if and only if $\beta\neq 0$; and $\A$ is Auslander-regular when $\beta \neq 0$. We also prove that the global dimension of $\A$ is $n+3$; and the algebra $\A$ is a prime ring except $\alpha=\beta=\phi=0$. Moreover, we obtain some results on the Krull dimension, isomorphisms, and automorphisms of the algebra $\A$.


Objective\ To understand the medical expenses and its related factors in Qingdao urban residents. \ Methods A cluster random sampling was carried out. 3 200 residents from 15 residential areas, based on economic status and locations, were investigated. \ Results\ The median of outpatient medical expenditures in Qingdao urban residents was 85.00 yuan.The expenditures were more in patients with chronic diseases, the disabled, female, and people who enjoyed free medical care or mainly at public expense. The median of inpatient medical expenditures was 3 600.00 yuan,there was a positive correlation between the age and inpatient medical expenditures( r=0.356,P 0.005). The main relevant factors of inpatient medical expenditures were age, occupations and medical insurance system. \ Conclusion\ Medical expenditures of urban residents in Qingdao are influenced by many factors. The medical and health care system should be reformed to meet the need of the residents.


The aim was to run a case study of a wheelchair sprinter's kinetics racing the 100m final at the 2016 Paralympic Games. The model features data collected beforehand by experimental testing, data collected over the race and a set of assumptions. Speed was measured by video analysis. Energy output and energy input (being the sum of the energy of the rolling friction, energy of the drag and kinetic energy) were estimated employing an analytical model. Energy input and output increased over the event. The Einput and Eoutput in the first split represents 27.66% and 17.18% of what was delivered in the end of the race. However we failed to note a steady-state or an impairment of both parameters in the last meters of the race. Data suggests that the 100m is a very short event, being the sprinter unable to achieve his maximal power in such distance.


Powered by solar energy, landscape water was treated by catalytic oxidation with manganese ore. The oxygen content is more than 90% in the gas which is generated by catalytic oxidation, therefore the oxygen transfer rate in oxygen aeration process is remarkable. The CODMn , concentration of aromatic compounds and algal biomass decreased and the biodegradable quality was improved.


Speed and capacity are not common considerations when people think about utility services such as gas, water, electricity and even phone lines. All of these services are critical to both homes and businesses, and of course people look for ways to reduce their monthly bills through efficient and judicious use of these resources. However, it's doubtful that you or anyone you know has turned on an electric or gas appliance, or picked up the phone and cursed at the slow speed of the gas, electricity or phone connection.


We studied NGFI‐A gene expression in response to photic stimulation in the rat suprachiasmatic nucleus (SCN) using in situ hybridization histochemistry. This gene expression spread within the SCN and extended dorsally into the anterior hypothalamus after 30 min–1 h of light exposure at circadian time (CT) CT18. It appeared first in the ventrolateral SCN where the retinohypothalamic tract (RHT) innervates, then it expanded dorsomedially in the SCN and beyond the SCN to the anterior hypothalamus. However, stimulation for 2 h light exposure decreased its expression in the SCN. NGFI‐A expression in the somatostatin neurons in the periventricular nucleus increased from 8.7% to 41% with increasing exposure time from 5 to 30 min. NGFI‐A mRNA expression in the SCN was suppressed by pretreatment with baclofen, the GABAB receptor agonist. The spread of photic information from the retina to the SCN was visualized at immediate early gene level not only in the SCN but also in the area beyond the SCN. Somatostatin neurons in the periventricular nucleus which project to the external layer of the median eminence and are involved in regulation of growth hormone release showed NGFI‐A gene expression corresponding to the duration of photic stimulation. Photic‐induced NGFI‐A gene expression in the SCN was also shown to be regulated by GABAergic transmission via GABAB receptors. These NGFI‐A gene‐expressing cells in the SCN may be involved in the circadian entrainment by light and some of those outside the SCN may participate in the regulation of neuroendocrine function.


One of the essential advantages that single-mode lasers can offer for high-resolution spectroscopy is the possibility of overcoming the limitation set by Doppler broadening. Several techniques have been developed that are based on selective saturation of atomic or molecular transitions by sufficiently intense lasers. The population density of molecules in the absorbing level is decreased by optical pumping. This results in a nonlinear dependence of the absorbed radiation power on the incident power. Such techniques are therefore summarized as nonlinear spec-troscopy, which also includes methods that are based on the simultaneous absorption of two or more photons during an atomic or molecular transition. In the following sections the basic physics and the experimental realization of some important methods of nonlinear spectroscopy are discussed. At first we shall, however, treat the saturation of population densities by intense incident radiation.


This paper has two complementary agendas. One is to develop a formal analysis of temporal ambiguity in self-identification. This refers specifically to having two conflicting orientations toward the future with regard to one's identity (e.g., a temporary expecting orientation and a permanent accepting orientation). I use the recovery identity (e.g., alcoholic, anorexic, agoraphobic) as a temporally ambiguous case because this identity is established as a means to an end but is susceptible to becoming an end in itself through identification with the disorder label. My analysis is based on the recovery narratives of individuals who have disidentified with their disorder labels; this allows for a consideration of the entire recovery career, from entry to exit. My second agenda is to explore the underresearched phenomenology of exiting from recovery identities specifically. Both of these agendas contribute new insight into identity research, labeling theory, and the sociology of mental health.


Key Points Question Is proton pump inhibitor (PPI) use during pregnancy associated with an increased risk of congenital malformations? Findings In this cohort study including 2 696 216 pregnancies in South Korea from 2011 to 2019, PPI use during the first trimester was not associated with a substantial increase in the risk of major congenital malformations, congenital heart defects, cleft palate, hydrocephalus, and hypospadias. Findings from the sibling-controlled analyses also revealed that PPIs were unlikely to be a major teratogen. Meaning These findings may help guide clinicians and patients in decision-making about PPI use in early pregnancy.


Industrial complexes have been regarded as important tools of industrial policy in Korea. In the process of industrial development, some industrial complexes have been blamed as major causes of environment-related problems. In response to social and environmental problems, researchers and policy makers have tried to introduce a new type of industrial complexes, which requires environmental performance and economic efficiency at the same time. As a result, 'Eco-industrial Park(EIP)' projects have already started up by the central government of Korea. The primary object of EIP approaches based on industrial ecology is to integrate firms' production systems and environmental management by forming networks of mutually beneficial symbiosis that mimic natural ecosystem. The government has already developed 5 EIPs and is now planning on developing more EIPs across the nation. Recently ever-first EIP Hub and Spoke strategies have been introduced in Korea, ending up in a 8 Hub EIPs. Throughout the EIP developments since the policy started, I came to know that there have been some issues and problems in the pre-existing national EIP development projects in terms of law and policy. Throughout years of experiences and researches, several important problems in recycling of resources have been exposed. Among those problems are ① Securing waste information and improving of waste database, ② Spatial restrictions of EIP Projects, ③ Lack of motivation to participate in symbiotic networks, ④ Policy banning recycling industries from locating in Industrial complexes, ⑤ Difficulties in linking to the regionally based recycling network. To solve those problems we can use several strategies. But when it comes to laws and policies in particular, revisions of these acts, ① Waste Control Act, ② Act on the Promotion of Saving and Recycling of Resources, ③ Act on the Promotion of Industrial Clusters and Plant Establishments, ④ Act on the Promotion of Change into Environmentally Friendly Industrial Structure, are crucial for the further development of the current EIP projects. Besides changes in these laws, basically a special law(for example, Act on Assistance for Industrial Symbiosis) dealing exclusively with industrial complexes can be another option in the long run. Also a regional-based recycling system needs to be introduced into Korea's EIP projects at the moment. These trials can be much of help with shrinking EIP projects and waste exchange activities leading to Korean version of EIPs and cyclical society.


The technic capability of new type Selective Level Meter and Level Oscillator adopting Direct Digital Synthesis(DDS)is advanced notability,it makes stability of frequency achieve level of crystal?


This brief shows how to combine SIMSIDES, a SIMULINK-based time-domain behavioral simulator, with different optimization engines available in MATLAB for the automated high-level design of sigma-delta (<inline-formula> <tex-math notation="LaTeX">${\Sigma \Delta }$ </tex-math></inline-formula>) modulators. To this purpose, an updated version of SIMSIDES has been developed, which includes a user-friendly interface that links the simulator with the optimizers, and guides designers through the main steps required to set the design variables, constraints and select the most suitable algorithm to maximize the performance of an arbitrary modulator topology for a given set of specifications. Several examples and results of the optimization procedure are shown to illustrate the benefits of the presented tool for the high-level synthesis of <inline-formula> <tex-math notation="LaTeX">${\Sigma \Delta }$ </tex-math></inline-formula> modulators.


This work explores the breakdown of the wake downstream of the MEXICO rotor and assesses the capability of CFD
in predicting its correct physical mechanism. The wake is resolved on a fine mesh able to capture the vortices up to
8 radii downstream of the blades. At a wind speed of 15m/s, the main frequency present in the CFD signals for up
to 4 radii was the blade passing frequency (21.4Hz), where the vortex cores fall on a perfect spiral. Between 4 and
5 radii downstream, higher frequency content was present, which indicates the onset of instabilities and resulted in
vortex pairing. The effect of modeling a single-blade domain and a full rotor domain was studied, showing similar
prediction of the location of the onset of instabilities, but an increased frequency content was captured in the latter
case. Empirical and wake models were also explored, and compared with CFD and a combination of kinematic and
field models was proposed. The encouraging results obtained suggest that the wake instability of wind turbines can be
predicted with CFD methods, provided adequate mesh resolution is used.


We propose xDIoT, a paradigm for reliable cross-domain communication across separated IoT network domains over some public network such as the Internet. Depending on use-case scenarios, several individual IoT domains, each consisting of heterogeneous end-devices (sensors and actuators) are deployed across geographical regions. When these domains need to communicate with one another they can use an intermediate public network like the Internet. To this end, a standard paradigm is required for such inter-domain communication over public networks to reduce latencies and prevent inconsistencies, which is absent in current deployments. With xDIoT we address this issue to provide a uniform communication paradigm. In xDIoT, each individual domain has an associated gateway access point (AP) acting as the bridge between the intra-domain IoT network and the external public network. These APs perform Domain Information Exchange through JSON format to gain knowledge about each other and use a generalized packet header structure to encapsulate all data flowing between these APs. Through the use of JSON data exchange and the proposed packet header, the APs can perform seamless inter-domain communication. Implementation and analysis show that xDIoT achieves about 10% improvement in total communication latency with 80% improvement in packet processing time at individual gateway APs.


A ridged-type magnetostatic waveguide is analyzed using the boundary element method. A bias magnetic field is applied perpendicularly to the surface of an yttrium-iron-garnet (YIG) film grown on a gadlinium-gallium-garnet (GGG) substrate. The dispersion curves and the potential profiles obtained in this paper show that the mode has a strong nonreciprocal property and is a kind of edge-guided mode which propagates along either side of the ridge, depending upon the direction of the bias field and the direction of the wave propagation. In addition, the authors emphasize the fact that the boundary element method is useful for analysis of a complex structure in the field of magnetostatic wave (MSW) devices.


There exists a variety of problems in English and American literature including improper textbook compliation and tedious teaching methods.To tackle these problems.This paper suggests three effective leadin strategies:see and feel strategy,strategy of selecting words and expressions provided for characters,and strategy of texts juxtaposition.


Abstract : The report evaluates the effects of redefining the role of a counselor in the AV(A) School so that intensified counseling is administered to potential failures before the trainee takes the unit examination as opposed to normal post-failure counseling. In addition, two types of remediation were evaluated. An existing system of one week set back review remediation was compared with a self-paced programmed instruction.


Traditional AAM (Active Appearance Models) improved methods on human facial features localization always concentrate on fitting efficiency without any concrete analysis of characteristic of the initial position and model instance, thus the location accuracy and speed are both not ideal. An initial position correction and model instance selection method based on facial features detection and simple 3D pose estimation is proposed. Adaboost algorithm is applied to pre-detection of facial features in the images firstly, then to extract features from the images that could not be detected or have been incompletely detected using facial skin properties in YCbCr color space. Finally,calculate the coordinate of the nose tip and deflection angle of the face according to features region, properly adjust the fitting center position and model instance and introduce linear algebra software ATLAS(Automatically Tuned Linear Algebra Software) into fitting process for matrixes optimization. Simulation experiments on IMM face database show that proposed method has increased the fitting accuracy rate by about 43% and the time consumption is decreased by about 62% comparing with traditional Inverse Compositional AAM Algorithm.


BACKGROUND
Retirement planning is an issue that concerns all working people. In this article, the authors present their analysis of the results of a 1995 American Dental Association survey that asked dentists questions about their plans to finance their retirement.

METHODS
The ADA's Survey Center conducts a periodic "Survey of Current Issues in Dentistry," which gauges dentists' opinions about a variety of topics of interest to dentistry. The authors analyzed the results of the 1995 survey in which retirement savings was one of the topics.

RESULTS
The majority of responding owner/dentists whose primary occupation was private practice (40.7 percent) indicated that they were relying only "a little" on the sales of their practices to finance their retirements. Overall, dentists whose primary occupation was private practice reported saving an average of 10.5 percent of their income specifically for retirement. The average total amount of money dentists invested in various retirement plans increased with age and was highest for the 55 to 59 and the 60 to 64 years of age cohorts. The only exception was the 401(k) plan, in which the peak occurred in the 65 years of age and older cohort.

CONCLUSIONS
Fifteen years ago most dentists retired between the ages of 60 and 69 years. Recent trends show that dentists are retiring at younger ages. This means that while in practice, dentists must save enough to support themselves for 20 or more years of retirement.

PRACTICE IMPLICATIONS
The transition from private practice to retirement can be difficult. Therefore, planning for the future is important. Dentists can benefit from making appropriate decisions based on age, investment goals, risk tolerance, monetary constraints and time until retirement.


Following previous investigations on different species of Tanacetum, as a novel survey, this study was conducted with the aim to evaluation of the antibacterial effect of the total methanol extract Tanacetum frutoculosum Lebeb and its Sub,fractions against 6 bacterial strains including: Staphylococcus aureus ATCC 6538 , Staphylococcus epidermidis ATCC 12228, Methicillin resistant Staphylococcus aureus ATCC 33591 , Salmonella typhimurium ATCC 14028 , Pseudomonas aeruginosa ATCC 9027 and Escherichia Coli ATCC 8739. Primarily antibacterial effects were investigated by the Agar well diffusion method and then Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC) were determined using broth Macro dilution method. The total phenolic and flavonoid contents of the extract and its fractions were measured based on gallic acid and rutin equivalents (GAE and RE) respectively. The total methanol extract showed the highest phenolic and flavonoid contents (1.858mg GEA/g and 21mg RE/g respectively) and had the highest antibacterial effect against S. epidermidis (MIC 15.62 mg/ml). The petroleum ether fraction showed the lowest phenolic and flavonoid contents (0.760mg GAE/g and 11.6 mg RE/g respectively) and had the lowest antibacterial activity against P. aueroginosa (MIC 250 mg/ml). These findings demonstrated the plant potential antibacterial effect against various human pathogenic bacteria.


Novel bent-core molecules based on phenyl benzoate rigid cores and heptamethyltrisiloxane units at one or at both ends of the aliphatic side chains were synthesized and investigated by polarized light microscopy, differential scanning calorimetry, X-ray diffraction and electrooptical methods and the effect of the direction of the carboxyl groups on the mesomorphic self assembly was investigated. A series of distinct liquid crystalline phases was found, among them ferroelectric and antiferroelectric switching and also non-switchable smectic, undulated smectic (USmC) and modulated smectic phases (columnar phases, Colob). All polar phases show field-induced inversion of chirality at least in a certain temperature range. Moreover, two non-polar and uniaxial smectic phases were observed, one with a hollow cone-like orientational director distribution (SmCR) and the other one with a maximum of the director distribution at zero tilt (SmA). These two phases were discussed in relation to the distinct models of de Vries type smectic phases.


The freezing potential (Ef) of water–ethanol mixtures containing lithium chloride has been recorded with a temporal resolution of 1 ms. Two sharp peaks (Ef1 and Ef2) and a subsequent maximum (Emf) appeared on the Ef-time curves. Addition of 0.001% v/v ethanol caused oscillation of Ef after Emf. Further addition of ethanol (0.1–1%) led only to the first peak, Ef1, and subsequent exponential relaxation, followed by the delayed oscillation of the electrical potential after 70 s. The peak positions and their relaxation depended strongly on ethanol content and cooling rate. The positive potential decreased steeply beyond 0.03% ethanol to become negative at 1% ethanol. The LiCl concentrations at which the FP appeared were in the region of 10–6–0.1 mol dm–3 LiCl, depending on the ethanol content. The structure of the ice deposited from any solution on a glass plate was of /h type, with some variation of crystallite size and orientation with ethanol content. A. mechanism for the occurrence of Ef and the effects of ethanol on Ef are discussed.


Various themes and studies continue to be developed in the context of BIPA learning in Indonesia. This is one of the impacts of the rapid development of BIPA learning in Indonesia and abroad. Therefore, a study is needed so that it can further enrich the study of BIPA learning. One of studies that can be offered is the study of the Nusantara culture. The culture of the Nusantara has a wide range of materials. One interesting form of Nusantara culture to be used as teaching material is Dhaup Ageng or wedding ceremonies organized by the Palace/Palace of Pura Pakulaman Yogyakarta, which can be used as an introduction to the culture of the Nusantara. The series of processions and ceremonial equipment that accompany Dheng Ageng has a strong appeal for foreign people and therefore could be used as BIPA learning materials.


Blockchain is a staggering innovation with possibilities to change business, particularly in developing business sector global partnerships. Blockchain innovation is a circulated and decentralized record framework that can record exchanges between various PCs. The innovation is viewed as a solid online protection convention because of its abilities of showing any injustice and giving sureness in the trustworthiness of exchanges. The blockchain is another creative innovation that is in the period of being taken on by associations for overseeing records.


Abstract The present study investigated the impact of nickel (Ni2+) on trans-membrane electrical potential (EM) and permeability properties of plasma membrane (PM) in epidermal cells of adventitious grapevine roots. The relationship between disturbances of membrane functionality and the production of superoxide anion, hydrogen peroxide and cell viability after the exposure of roots to Ni2+ was also studied. Treatments with 0.1-5 mmol L-1 NiCl2 induced a concentration-dependent transient PM depolarization, which was recovered to the initial resting potential within 50-70 min in the presence of Ni2+. Longer (up to 24 h) exposure of roots to 1 mmol L-1 of Ni2+ hyperpolarized the EM by approximately 17 mV. Application of the highest 5 mmol L-1 concentration of Ni2+ during longer treatments (up to 48 h) resulted in the increase of membrane permeability; however the EM, cell viability, and superoxide content remained unaffected. The increase in the formation of hydrogen peroxide was time- and concentration- dependent and maximum production was recorded after 180 min of Ni2+ treatment. We can conclude that oxidative stress resulting from an imbalance in the generation and/ or removal of hydrogen peroxide in the root tissues of grapevine was the major cause of Ni2+ toxicity.


The CLAN intellectual property core is a CAN 2.0b controller developed at the Electronics and Telecommunications Department of the University of Aveiro, for research and educational purposes and in particular with the aim of providing the adequate hardware support to implement and validate higher layer protocols such as TTCAN or FTT- CAN. It was modelled at RTL level using the VHDL hardware description language, synthesized, implemented and tested on Xilinx FPGAs. However, the model is technology independent and can be synthesized for different implementation technologies from FPGAs to ASICs. The CLAN IP core fully implements the CAN 2.0B spacification and it includes also a syncronous parallel microprocessor interface, interrupt generation logic and some advanced features, such as message filtering, single shot transmission and extended error and statistics logs. The data bus width can be 8, 16 or 32 bits wide. For aplications where a microprocessor interface is not needed or a different interface is required, the core internal module that implaments the protocol can be used separately. CLAN controller with microprocessor interface logic occupies about 30% of a Xilins Spartan-UE XC2S300E FPGA, corresponding to 100.000 equivalent logic gates, approximately. It was tested with other CAN controllers operating at 1Mbit/seg.


None of the commonly used staging criteria accurately determine the prognosis of a patient with adenocarcinoma of Barrett's esophagus. The authors therefore assessed the expression pattern and prognostic impact of CD44 standard and CD44 isoforms CD44v4, v5,v6,v7, and v10 in adenocarcinoma of Barrett's esophagus.


An ion-pair high performance LC method for simultaneous determination of water-soluble vitamins: VitB_1,VitB_2,VitB_6,niacin,niacination and folic acid was developed.The HPLC system was consisted of Nova-Pak~C_(18)(150 mm×3.9 mm),UV detector wavelengths(254 nm and 285 nm)and the flow rate was 0.8 mL·min~(-1).The experiment showed that the relative standard deviations of the results are ranging from 1.25% to 5.2%,the average recoveries for the determination are ranging from 97% to 112%,the linearity relation coefficient is between 0.999 8 to 0.999 9 in the concentration range of 0-50 mg·L~(-1)((n=5)) and detection limits are from 0.05 to 0.62 mg·L~(-1).