This chapter explores the evolving nature and status of curatorial theory in the museum. Simply stated, curatorial theory may be defined as the complex compendia of ideas and beliefs that shape and inform curatorial work. Drawing on sources ranging from early twentieth-century museum literature to contemporary interviews with museum curators, directors, and theorists, this examination traces the historical development of curatorship and aims to give voice to the experience of past and present participants within the museum field. This exploration operates under the assumption that theory and practice are fundamentally intertwined; when we speak of one we necessarily invoke the other. Guided by this conviction, it endeavors to focus attention on the commonality that is to be found in the experience of curators of various disciplines. Simultaneously, it seeks to engender a more nuanced awareness of some of the subtle continuities (and discontinuities) that connect (and separate) the ideas and practices of curators to one another across space and time.

Keywords:

contemporary trends;
continuities;
curator;
curatorial practice;
curatorial theory;
curatorship;
gallery;
history;
museum


System level functional verification by running real software stack on FPGA prototype is essential for achieving a high quality design. But it is hard to find the exact source of hardware function faults while running large closed source system software fails. This paper proposes the idea of tracking down faults through real system software control flow invariants with current trace output hardware support. It captures qualified control flow invariant trace in reference execution and test trace; and tracks down faults through comparing offline invariant trace and test trace. The approach can deal with both deterministic and nondeterministic execution. We implemented the proof of concept in full system simulator Bochs. Our experimentation with the real closed source MS Windows XP suggests that the approach is effective in tracking down hardware function faults.


Fluoroacetone (I) has been prepared through dimethyl cadmium and fluo-roacetyl chloride with promising yield of 84%. α-Fluoromethacrylonitrile (VI),α-fluoromethacrylamide (VIII) and methyl α-fluoromethacrylate (VII) have beensynthesized and characterized. All these three new monomers polymerize readilyand the polymers obtained have much higher softening points than the corres-ponding α-methyl-vinyl compounds. According to our preliminary observations,the excellent high softening points (about 250℃), freedom from color andglass-like clarity, the methyl α-fluoromethacrylate polymers may make themin demand for high-quality glasses for high-speed aeroplane.


Planetary missions pose special challenges to solar panels because of the wide range of illumination intensities and temperatures. Some missions have both near-sun and far-sun operation requirements, which impart both high illumination, high temperature and low illumination, low temperature operating regimes on the solar panel. At first, a solar concentrator may seem to be a counter-intuitive choice for surviving near-sun environments, however, we describe here an approach to using a high concentration ratio design to improve the ability to operate in both near-sun and far-sun conditions. A modular off-axis reflective concentrator was chosen as the basis for the deep space concentrator (DSC) design. Optical and thermal analysis was performed to show the ability of the design to withstand near and far-sun environments. A test model was built using graphite fiber reinforced composite (GFRC) mirrors and a GaAs solar cell receiver to demonstrate the ability to obtain tight pointing tolerance in a lightweight, thermally stable design.


Human flow counting is a fundamental task in public space management. Counting flow correctly may help prevent overcrowding hazards and improve public safety. This study proposes an automated device-free flow counting system by exploiting radio frequency irregularity in a wireless sensor network. As people pass through the line-of-sight between transmitters and receivers, radio frequency transmission is disturbed and received signal strength indicator (RSSI) fluctuates at the receiving ends. Using RSSI fluctuation series, the system infers flow size without patrons' carrying any special devices. A wireless sensor network with HBE-Zigbex motes (IEEE 802.15.4) is set up to conduct experiments. Besides the mean and standard deviation of RSSI fluctuation series, Fourier spectral features are also employed as predictors of a machine learning algorithm. Experimental results show that spectral features improve the prediction accuracy significantly. The proposed method thus provides an alternative solution for the flow counting problem in addition to other video based solutions.


and governments, all of which necessitate the party's close involvement in the league's work. Thus, any impetus for the league's involvement in new areas of work derives from party and government priorities, limiting the league's own initiatives. He notes that the Youth League combines two organizational identities based on its different functions. The league is a powerful promotion mechanism that acts as a channel for the party's personnel 'rejuvenation' and as the platform for the creation of personal networks, political alliances, and functions. At the same time, it is a weak youth organization that lacks the autonomy and capacity necessary to carry out social work and increase its participatory character (p. 242). Clearly, the first identity is paramount. The volume also includes a very helpful discussion of the declining fortunes of the Youth League under Xi Jinping, who not only viewed the league as a bastion of factionalism – the so-called 'league faction' (团派) that provided a base of support for the Hu Jintao and Wen Jiabao administration – but also as an obstacle to his political vision for mass organizations, which emphasizes their political character, mandating even closer management by the party. Thus, under Xi, the Youth League has downsized its membership, had its budget substantially reduced, and had its personnel redistributed away from the centre and down to the local levels, among other changes. In August 2016, the state media laid out the party's substantial reform programme for the league, effectively rendering it politically irrelevant. As Tsimonis concludes, Xi's reforms promote 'an even more sterile and formal engagement of Youth League organizations with young people, with an emphasis on routine indoctrination and propaganda functions' (p. 248), a lost opportunity indeed. Fortunately, we have this excellent book by Tsimonis to enlighten us on why Hu's reforms were doomed from the start.


The aims of this study is to know the influence of agglomeration in East Java. The data consists of 38 regions in which 29 ofthem are districts and 8 ofthem are cities during the 2000-2009 periods. The data used in this study is secondaiy data in theform of numbers so that this study will lead to quantitative Study. Based on the characteristics ofthe problem, this studv is categorized into causal-comparative studv The moe of the data is panel data and the method used is GLS (General Least Square) to process the panel data calculation. Several factors which influence the economic growth are the agglomeration QYI), the labor (XZ), the inflation 0(3) openness rate (X4), and human capita/ (X5). The conclusion of this studv is that the economic growth in East Java is influenced by either agglomeration and education (human capital) that have positive ef/'ect with significant va/ue, and also the inflation and export (openness rate), although the value is not significant. Agglome/ration, labor, and education (human capitaU are the ones which have the positive relationship with the economic growth. Therefore, it is expected that the local government can create employments in industrial sector and increase the quality ofthe education in East Java so that the good economic growth can be obtained Keywords: Agglomeration, Human Capital, Economic Growth, and Pane Data.


The transition states associated to the dynamics of a model lipid bilayer membrane have been investigated by means of molecular-dynamics transition path sampling. We have focused on the flip-flop transition of a lipid molecule between the two sides of a flexible membrane. In the transition state, a local collective reorganization is necessary to allow a lipid molecule to move from one interface of the bilayer to the second one. The elapsed time for flip-flop has been estimated to be 0.27 ps, whereas the increase in configurational energy during the flip-flop transition is of about 15 kJ/mol.


(57) Tin brass alloy having SUMMARY small amounts of grain structure of both of zinc and iron was refined by the addition is provided. In a weight ratio, 1-4% tin, iron from 0.8 to 4%, direct chill of copper and inevitable impurities is an amount of zinc, and the balance to reach 35% from the amount that can increase the grain refinement with iron led cast alloy is easily hot worked. The addition of zinc further increased strength of the alloy, to improve the bending of the direction perpendicular to the "good direction" or the longitudinal axis of the rolled strip. Those of certain grain miniaturized brass is useful as a semi-solid molding material.


Objective To investigate the protective effect of SanjingRuipu SUGAR REDUCING DEVICE on fuction and structure of sciatic nerve in diabetic rats.Methods Diabetic rats were treated with SanjingRuipu SUGAR REDUCING DEVICE for eight weeks,then advanced glycation end products(AGEs)of the sciatic nerve and conduction velocity in sciatic nerve of diabetic rats were measured.Results SanjingRuipu SUGAR REDUCING DEVINCE was able to reduce accumulation of AGEs in sciatic nerve,and to improve sciatic nerve conduction velocity partly.Conclusion These findings suggested that SanjingRuipu SUGAR REDUCING DEVICE might be a valuable tool in treatment of diabetic peripheral neurpathy.


New ionic liquids–aqueous biphasic systems (ABS) containing the imidazolium and pyrrolodinium cation combined with dicyanamide anion and citrate organic salts are investigated. Several ionic liquids (five in total) were evaluated toward their capacity to create aqueous biphasic systems in the presence of two low environmental impact organic salts: potassium and sodium citrate. The capacity of these ILs to form two liquid phases is discussed regarding the alkyl chain length and the cation core of the IL. Besides, the effect of the citrate salt on the phase behavior has been also addressed. To study the capacity of the ABS the binodal curves were determined at T = 298.15 K and atmospheric pressure. Finally, a comparison between the experimental results obtained here and the literature values was carried out.


Introduction: Randomized studies on pulmonary tele-rehabilitation (PTR) in people with COPD has shown positive short-term effects on physical capacity compared to conventional PR. No data on the potential for long-term sustainability from PTR exist. Aim: To investigate if PTR has long-term superiority to conventional PR on walking capacity (6MWD) and secondarily on the following outcomes: symptoms (CAT, HADS), quality of life (EQ-5D), physical activity level (accelerometer), mortality and hospitalizations. Methods: In a multicenter RCT, people with severe COPD (FEV1 Results: 134 participants (74 females, mean±SD age 68±9 years, FEV1 33±9 % predicted, 6MWD 327±103) were randomized 1:1. Intention-to-treat analysis showed no between-group differences for 6MWD at 12-month follow-up [5.7meters (95%CI: -24.8; 36.1)], similar to our previously published short-term effects. None of the within group short-term improvements after intervention were maintained. There were no statistical between-groups difference in respiratory hospitalization [HR: 1.08 (0.57; 1.99), all-cause hospitalization [HR: 1.16 (0.76; 1.78)] or mortality. Conclusion: Pulmonary tele-rehabilitation was not superior to conventional PR at 12-month follow-up. PTR has similar limitations regarding long-term sustainability as conventional PR.


From the bark of Rhamnus frangula a new glycoside has been isolated and its structure elucidated as emodin-8-Ob-gentiobioside. The structure was confirmed by glycosidation of 6-0-benzoyl-emodin ,with a-acetobromgentiobiose in a Koenigs-Knorr reaction followed by saponification. Results and Discussion In addition to glucofrangulin A/B, whose structures have been elucidated in our laboratory [I, 21 we have detected in the frangula extract a hitherto unknown anthraquinone glycoside with a Rf value more polar than that of glucofrangulin 131. We obtained the new glycoside in good yield by column chromatography on polyamide and silica gel followed by preparative thin layer . . chromatography. The pure glycoside had a mp of 199-201 and gave emodin and glucose as the only products of acid hydrolysis. In the mass spectrum of the permethylated glycoside a signal a t mle 422 showed the presence of a diglucosyl unit. The molecule peak at mle 720 had a relative intensity of 1 O/o. All the other fragment ions were in agreement with an emodin-0-diglucoside structure. The disaccharide moiety possesses a 1 -t 6 linkage, since after permethylation, hydrolysis and reduction 1,5-di-0-acetyl2, 3, 4, 6-tetra-0-methylglucitol and 1, 5, 6-tri-0-acetyl-2, 3, 4-tri-0-methylglucitol could be identified in the gaschromatogram and by GC-MS. This further proves their pyranose conformation. Part IV: WAGNER, H. and DEMUTH, G.: 2. Naturforsch. 31 b, 267 (1976). "" deceased November 1976.


In this paper, we mainly investigate the character of consensus convergence speed of Multi-Agent Systems (MAS) with small-world communication network and the method of devising a speed-optimized small-world communication network in consensus problem based on genetic-algorithm (GA). It is found that, for a small-world communication network, the time to reach a consensus changes rapidly with the change of the number of long-range communication links and the agents which the long-range links connect. The convergence speed of consensus of MAS increases rapidly with the number of long-range links increasing. As we construct a small-world communication network for MAS with a smaller network size and fixed long-range links, we can optimize the long-range link configuration using GA methodology to obtain a small-world communication network with faster consensus speed for MAS.


In this article, Dr Karen Jones invites us to embark upon a creative analysis of youth culture. Drawing primarily on sociological and cultural studies, Jones encourages us to look beyond group analysis and seek to engage primarily with the cluster of individuals that exist within that group.


The therapeutic care pathway for a patient with a stoma starts with a preoperative diagnosis and the decision to form an ostomy, followed by postoperative education, and it continues for as long as the stoma is in place. Clinical studies in this area are often limited to analysing a specific stage in this process, and less attention has been given to how each stage influences the rest of the pathway. This study aimed to provide a holistic assessment of the entire stoma care pathway, encompassing professional management of emerging complications, as well as the patient's perceptions of care and capacity for self-management, to determine how one management stage might affect another. The study consisted of an anonymous questionnaire with 96 items divided into nine sections. It enrolled people with one or more urinary and/or intestinal stoma/s and lasted from September 2017 to December 2019. In the sample of 403 ostomates, 52% were female and 48% male, while 74% had an intestinal stoma, 19% a urinary stoma and 7% both. Of all respondents, 52% presented with peristomal lesions. Pre-operatively, a lack of training (76%), stoma siting (70%) and psychological support (92%) were observed. After discharge, 75% had peristomal lesions, 47% had professional care. At the time of the study, 60% were self-sufficient in ostomy care, 52% had lesions, while 38% were unsatisfied with the device used. Detailed discussion is given to peristomal skin care, self-sufficiency, ongoing support and the needs of people with both a urinary and an intestinal stoma. Patient education, psychological support and access to a stoma care specialist all likely affect acceptance and quality of life.


The Bureau of Social Research, within a strategic EU project– Rural Entrepreneur (2011) – coordinated by the National Foundation of Young Managers, analyzed in 2001 the needs of developing management and consultancy programs in order to improve the knowledge, skills, and managerial behaviour of the small and prospective entrepreneurs from the rural area of Romania. This study has revealed that three quarters of the rural entrepreneurs and over 85% of the prospective entrepreneurs have never been trained in management development. Their managerial education is often poor and usually acquired after starting the business up. The majority does not even consider that a prior training is necessary because business opportunities in the rural area are rare and the access of European funding is difficult. Over 90% of the new businesses fail in the first year. The managerial training programs and entrepreneurial consultancy can significantly reduce this percentage.


An air mat having an air blowing function is provided to remove the inconvenience of attaching or detaching an existing air blower, to increase the function of the air blower and to prevent the air blower from being exposed to the outside of the mat. An air mat having an air blowing function includes a mat body(20), a support layer(30), and an air blower. The support layer(30) is attached to one side of the mat body(20). Plural supports(32) are consecutively installed on the inner side of the support layer(30), and an air path(34) is formed between the plural pillar shaped supports(32). The air blower is mounted between the mat body(20) and the support layer(30) to send air to the air path(34). An air outlet(36) is formed in a direction of the outer surface of the support layer(30) to communicate with the air path.


Immediately following birth, the newborn remains attached to the mother via the placenta and umbilical cord. During this period, the blood transferred from the placenta to newborn is known as placental transfusion. Placental transfusion can contribute between one-quarter and one-third of the total blood volume of the newborn (80–85 ml/kg) and delayed cord clamping (DCC), can reduce the hypovolemic damage, long term difficulties and even disability associated with early cord clamping (ECC). DCC also increases iron stores in infancy (Andersson et al, 2011); higher iron levels have been found to correlate with improved neurological and cognitive development (Szajewska, 2010). Through integrating DCC into routine third stage management, both mother and newborn can benefit from improved outcomes. With such compelling evidence, why do hospital protocols and guidelines not reflect the latest evidence? And why are women not being given the opportunity for informed choice on such an important issue?.


Abstract Despite it looks homogeneous, the genus Utricularia shows a great ecological and biological diversity. Because of their varius ways of life, Utricularias are to be found in all environments, provided they are wet and oligotrophic. All the species share the same flower organization, typically adapted to xenogamic reproduction. Nevertheless autogamy is often observed, either constant or casual. Cleistogamy is observed too. Two kinds of cleistogamy are noticed. Opportunistic cleistogamy is a phenomenon frequently seen in many other families, it is a response to a temporary ecological stress. Quite the reverse, architectural cleistogamy looks very scarce in other families: chasmogamous flowers are always coexisting with cleistogamous ones, each of them are located in different, and well defined, parts of the inflorescence. Considering these observations, evolutive trends can be proposed within this highly differenciated genus.


We investigated the short-term effects of a phosphodiesterase III Inhibitor (Olprinone) on hemodynamics and thoracic duct lymph flow in anesthetized open-chest sheep with heart failure induced by endothelin-l (cardiogenic shock). Ultrasound transit-time flow probes were attached to the thoracic duct, the ascending aorta and the renal artery. Arterial, pulmonary and central venous pressures were monitored. Endothelin-l was infused intravenously at a dosage that reduced cardiac output to 50% or more of baseline (n =11). The effects of Olprinone were examined (n=5) by intravenous infusion after endothelin-l administration. Other sheep (n=6) were used as controls. Olprinone significantly increased cardiac output that had been decreased by endothelin-l and further increased thoracic duct flow that had been increased by endothelin-l. Increased arterial and pulmonary pressures induced by endothelin-l administration were rapidly decreased by Olprinone. Renal arterial flow and central venous pressure were, however, unchanged by Olprinone. Overall, Olprinone acutely improved experimental cardiogenic shock (heart failure) induced by endothelin-l, and maintained thoracic duct lymph flow at a high level after endothelin-l administration. Endothelin-l (ET-l) is a peptide implicated in various pathological states (1) including heart failure (2). During heart failure, systemic and pulmonary edema are induced if both the right and left ventricles fail to contract optimally. With decreased blood flow from lowered cardiac output, edema worsens systemic organ and pulmonary function by decreased tissue oxygenation. Therefore, improvement of edema (both pulmonary and systemic) in heart failure is desirable to interrupt this vicious cycle. Lymph flow plays an important drainage role in both systemic and pulmonary edema. It has been our goal to improve edema in heart failure by augmenting lymph transport, and especially flow in the thoracic duct, the major pathway returning lymph to the central venous circulation. We have recently investigated lymph flow dynamics in the thoracic duct (3-5) and now applied these techniques to the treatment of fluid imbalances in experimental heart failure. To augment lymph flow, we chose to study a phosphodiesterase III (PDE III) inhibitor, namely Olprinone or OLP. A PDE III inhibitor has both cardiotonic and potent vasodilating effects (6,7) by increasing the intracellular concentration of cyclic adenosine monophosphate (8,9) and has been used for Permission granted for single print for individual use. Reproduction not permitted without permission of Journal LYMPHOLOGY . the treatment of acute heart failure (7,10). These hemodynamic responses to a PDE III inhibitor suggested to us that Olprinone might act to improve lymph flow dynamics including thoracic duct contraction. Accordingly, in the following experiments, we induced acute depression of cardiac output in sheep by administrating ET-1 and then examined the short-term effects of OLP on blood and lymph dynamics before, during, and after recovery of acute heart failure. MATERIALS AND METHODS Anesthetized Sheep Preparation This study was approved by the University Committee on Animal Resources and conformed to the guiding principles of our institution in the care and use of animals. Eleven mongrel sheep of either sex, with a mean weight of 49±2 kg, were used. Anesthesia was initiated with intramuscular injection of ketamine hydrochloride (10 mg/kg) and atropine sulfate (0.5 mg). After intravenous injection of thiopental sodium (5 mg/kg), an endotracheal tube was introduced. Respiration was controlled by a ventilator (Harvard pump Model No.607, Mass) under muscle relaxation using pancuronium bromide (0.05mg/kg/hr). Halothane (0.5-1.5%) was delivered from a calibrated vaporizer using a mixture of oxygen and room air. A tracheostomy was then performed and the long endotracheal tube was exchanged with a short tracheostomy tube to minimize tube complications. A catheter was inserted into the right common carotid artery and connected to a pressure transducer (MPU-0.5A, Nihon Kohden, Tokyo, Japan) for monitoring arterial blood pressure (ABP). A Swan-Ganz catheter was inserted via the right external jugular vein and connected to a low-pressure transducer (LPU-0.1A, Nihon Kohden) for measurement of central venous pressure (CVP) and pulmonary arterial pressure (PAP). Pressure data were recorded using a multi-channel 145 polygraph system (RM-6000, Nihon Kohden). With the sheep in the left lateral decubitus position, a right 7th intercostal thoracotomy was performed and an ultrasound transittime flow probe (Model H2SB, Transonic Systems Inc., Ithaca, NY) was attached to the thoracic duct for measurement of thoracic duct lymph flow (TDF). A right 4th intercostal thoracotomy was then performed, and an ultrasound transit-time flow probe (ModeI20SS, Transonic Systems Inc.) was attached to the root of the ascending aorta for measurement of cardiac output (CO). An ultrasound transit-time flow probe (Model H2.5SB, Transonic Systems Inc.) was also attached to the right renal artery using a retroperitoneal approach for measurement of renal blood flow (RBF). Each probe was connected to an ultrasound transit-time flow meter (Model H207 or H102, Transonic Systems Inc.). A computer (Model 2411 KitP95, IBM) and polygraph system recorded the flow parameters. Flow data were analyzed by using software (Flowtrace, Transonic Systems Inc.) and the average flow for each minute was calculated. Heart Failure Induced by ET-I In preliminary experiments, we defined heart failure as that condition in which CO had decreased to at least 50% of the baseline value. We also tested the effect ofET-1 on CO in anesthetized sheep using different amounts of ET-1 and different methods of ET-1 administration. These techniques included slow administration of ET-1 for 3 minutes or bolus administration for 1 second with 20, 200 or 400 pmol/kg body weight. These experiments showed the effect of ET-1 on CO was most intense after 200 pmol/kg of bolus administration or 400pmollkg of slow administration with the maximum decrease in CO occurring after the latter dosage and rate (11). Only slow administration of 400 pmol/kg of ET-1 produced a CO decrease of less than 50% of the baseline value with a maximum effect after -4-5 minutes from the Permission granted for single print for individual use. Reproduction not permitted without permission of Journal LYMPHOLOGY .


To address the issue of hazardous missions, this article uses the framework of shifts in missionary emphasis: from cross-cultural to intra-cultural mission, from first-generation to second-generation mission, and from human-centered to Earth-centered mission. The helpful or harmful characteristics of missionaries are not just personal hut also structural, that is, inherent in the culture from which the missionaries originate. This article suggests that the three related shifts in missionary emphasis noted above reduce the hazards of Christian mission, but in turn introduce some new hazards.


Objective To study the effects of benzene and the benzene metabolite hydroquinone on the cell cycle and apoptosis of peripheral blood lymphocytes,and to explore the molecular mechanisms underlying benzene-induced cytoxicity damage. Methods Human lymphatic cells were isolated,cultivated and then divided into three groups including of low,moderate,and high benzene exposure(0.25,3.5,50 μmol/L) and three groups of low,moderate,and high hydroquinone exposure(50,150,450 μmol/L).One solvent control and one blank control group were also set up.After the treatment,we assayed the growth arrest of lymphocytes induced by benzene and hydroquinone by methyl thiazolyl tetrazolium(MTT)test.Flow cytometry was applied to detect cell cycle and apoptosis rate.2,7-dichlorodihydro fluorescein diacetate(DCFH-DA) assay was used to detect reactive oxygen species(ROS) contents.Lymphocytes′DNA fragment was detected with single cell gel electrophoresis technology. Results The results showed that both benzene and hydroquinone decreased cell viability in a dose dependent manner,along with induction of S phase and G2/M phase arrest and increased late apoptosis.Meanwhile,benzene and hydroquinone induced accumulation of intracellular ROS in a dose-effect relationship.All data showed significant difference compared to control groups(P0.05).The mean tail lengths were 26.45±7.96 and 30.28±6.07 μm for groups of high levels of benzene and hydroquinone.The results revealed a significantly higher level of DNA damage in all concentration groups compared to control groups with a dose-effect relationship. Conclusion Benzene and its′ metabolite hydroquinone could induce decreased lymphocytes viability,dysfunction of cell cycle and programmed cell death.The results indicate that the overproduction of ROS and DNA lesion are likely to contribute to benzene-induced cytogenetic changes.


Methylation of histone H3 lysine 4 is linked to active transcription and can be removed by LSD1 or the JmjC domain–containing proteins by amino-oxidation or hydroxylation, respectively. Here we describe that its deamination can be catalyzed by lysyl oxidase–like 2 protein (LOXL2), presenting an unconventional chemical mechanism for H3K4 modification. Infrared spectroscopy and mass spectrometry analyses demonstrated that recombinant LOXL2 specifically deaminates trimethylated H3K4. Moreover, by regulating H3K4me3 deamination, LOXL2 activity is linked with the transcriptional control of the CDH1 gene. These results reveal the existence of further H3 modification as well as a novel mechanism for H3K4me3 demethylation. A cc ep te d A rt ic le This article is protected by copyright. All rights reserved. INTRODUCTION Transcriptional regulation involves interactions between transcription factors and chromatinmodifying complexes [1] that lead to changes in chromatin structure and histone modifications. One of the modifications linked to active transcription is histone methylation at lysine 4 [2]. LSD1 and JmjC domain–containing proteins are the enzymes identified to be responsible for H3K4 demethylation [3-5]. Several observations suggest the existence of additional demethylases that use other chemical mechanisms to demethylate lysine residues within histone H3 [6]. Here, we demonstrate that LOXL2, a Snail1-interacting protein [7], catalyzes an amino oxidase reaction to deaminate trimethylated lysine 4 in histone H3. LOXL2 is member of the lysyl oxidase (LOX) protein family, which are copper-containing enzymes that catalyze the oxidative deamination of the ε-amino groups in lysines [8]. While it is known that LOXL2 is involved in CDH1 repression and EMT induction [7], the specific mechanism of action remains elusive. We now find that LOXL2 is a histone modifier enzyme that removes trimethylated lysine 4 (K4) in histone H3 (H3K4me3) through an amino-oxidase reaction. As a result of LOXL2 oxidation, the trimethylated amino group is released, converting K4 into an allysine (H3K4ox). This study thus reveals the existence of a new type of modified H3.


Thyroid hormones and vitamin D both act through steroid receptors and are expected to affect each other's action. The study was planned to evaluate the association of Vitamin D with thyroid hormones as well as thyroid stimulating hormone. Vitamin D directly influences metabolism of calcium and phosphorus. The study therefore, further studied serum calcium and phosphorus levels in hypothyroid patients. Fifty patients diagnosed for hypothyroidism and fifty age and sex matched subjects were enrolled for the study. Blood samples were collected and analyzed for serum T3, T4, TSH, Vitamin D, Calcium and Phosphorus. On statistical evaluation, serum Vitamin D and calcium were observed to be significantly lower in hypothyroid group and exhibited a negative correlation with respect to TSH levels. The study infers that regular screening of above parameters in hypothyroid subjects can be helpful in managing and averting the associated complications of Vitamin D and calcium deficiency.


Social class, classism, and privilege and their relationship to counseling have been given insufficient attention. This article defines and explores White middle-class privilege; it proffers support for its integration in a multicultural competency, as well as its intersection with race and other dimensions of multiculturalism and privilege. Implications for counseling practice plus a clinical case study illustrate the issues.

La clase social, el clasismo y el privilegio, asi como su relacion con la consejeria, no han sido tratados con suficiente atencion. Este articulo define y explora el privilegio de la clase media Blanca; sugiere apoyar su integracion en una competencia multicultural, ademas de su interseccion con la raza y otras dimensiones del multiculturalismo y el privilegio. Las implicaciones para la practica de la consejeria mas el estudio de un caso clinico ilustran estan cuestiones.


Reflectivity spectra of NaH 3 (SeO 3 ) 2 crystals were measured form 16 to 400 cm -1 at 300°K and 202°K, and complex dielectric constants were derived using the K. K. dispersion relation. The results suggest that the dielectric dispersions occur around a few tens of cm -1 with a wide distribution of dispersion frequency.


The detection, classification, and localization of targets or features on the seafloor in acoustic data are critical to many disciplines. This is most important in cases where human safety is in jeopardy, such as hazards to navigation, mitigation of mine countermeasures, or unexploded ordnance. This study quantifies the absolute localization of targets, in the form of inert unexploded ordnance, in very shallow waters (2–3 m) on two intertidal bottom types in a meso-tidal environment (tide range = ~3.0 m). The two sites, a sandy intertidal flat and a mixed sand and gravel beach with abundant cobble-sized material, were seeded at low tide with targets (wax-filled 60-, 81-, 105- and 155-mm, projectile and mortar shells). An RTK-GPS was used to collect positional data for the targets and an unoccupied aerial system (UAS) survey was conducted on both sites. At the next high-tide, a vessel-based acoustic survey was performed, and at the subsequent low tide, the targets were re-surveyed with RTK-GPS. We focus here on the sidescan backscatter from a phase-measuring sidescan sonar (PMSS) and the sources of uncertainty for absolute localization. A total of 1426 calls of acoustic targets were made within the sidescan backscatter data, yielding an accuracy of 0.41 ± 0.26 m, with 98.9% of all calls <1 m from their absolute location. Distance from nadir was the most significant source of uncertainty, and targets between 3–7 m had the lowest uncertainty (0.32 ± 0.23 m) with increasing values toward and away from nadir. Bathymetry and bathymetry-mode backscatter were less useful for the detection and classification of targets compared to sidescan backscatter, but once detected, the accuracy of absolute localization were similar. This is likely due to target calls from these two datasets that were orders of magnitude less and that focused on the larger sized targets, thus more work is needed to better understand these differences. Lastly, the absolute localization of targets detected on sandy and cobble bottoms for all datasets were statistically similar. These acoustic instruments, their datasets, and methods presented herein can better document the absolute localization within acoustic data for many uses in very shallow waters.


(From 2Vew York Times, November 17, 1906.) "The Strange Case of Dr. Bruno" (New York: Guarantee Publishing Company). The case is ingeniously invented. A gentleman of wealth and German descent and education, who has his happiness wrecked by a con spiracy of cruel fate, goes to school to the mud wasp or "dirt-dauber" to find a drug which will suspend all the faculties in such a fashion as to preserve life under the appearance of death. Thus the mud wasp pre serves the spider as fresh meat for her young, and Dr. Bruno obtains a fluid chemically similar to that in the sac behind the wasp's sting, which he tries upon mice, pigs and monkeys, till he is sure enough of his results to experiment upon himself. He times the dose for six months and one hour precisely and lies down to pass that space in a state of animation so suspended that, as there shall be little or no waste, so there shall be no need of sustenance. The outcome of the experiment appears in the story, which deals very tragically with the passion of love and involves two beautiful women and two very handsome men. The scene is laid in New Orleans and in the city of Jackson, Miss., and the author, F. E. Daniel, M. D., has availed himself of all the tricks of melodrama to spice the dish of his medical fancy. The medical fancies are better than the rest—have, in fact, a quite convincing air of verisimilitude.


This paper is motivated by the debate over the practicality of International Accounting Standards (IAS) in transitional economies as well as improvements in the Chinese capital market infrastructure in recent years. This study explores whether IAS is more value-relevant than PRC GAAP, and whether the value-relevance of IAS and the Chinese GAAP has decreased over time in the Chinese capital market. This study adopts the Ohlson (1995) valuation model and the Vuong (1989) z-test to compare value-relevance and value-relevance over time in Chinese A-share and B-share markets from 1997 to 2003. The results indicate that IAS does not provide greater explanatory power than Chinese GAAP for A-share investors. The yearly analyses suggest the total explanatory power of IAS earnings and book value has decreased over time in the B-share market due to ineffective enforcement in compliance with IAS. While the explanatory power of PRC earnings and book values has increased from 2001 in the A-share market due to the improvement of the capital market infrastructure in recent years value-relevance has declined.-The latter is related to inefficient enforcement of full compliance with IAS and PRC GAAP, more firms reporting negative earnings and more firms with intangible-intensity. Small-sized firm and firms reporting negative earnings shift value-relevance to book values.


The nature of surfaces and the way they interact with each other during sliding contact can have a direct bearing on the performance of a microelectromechanical (MEMS) device. Therefore, a study was undertaken to characterize the surfaces of LIGA fabricated Ni and Cu components. Sidewall and planar surfaces were examined by scanning electron microscopy (SEM) and atomic force microscopy (AFM). Surface roughness was quantified using the AFM. Post-processing (e.g. lapping, removal of polymer film) can profoundly influence the morphology of LIGA components. Edge rounding and smearing of ductile materials during lapping can result in undesirable sidewall morphologies. By judicious selection of AFM scan sizes, the native roughness ({approximately}10 nm RMS) can be distinguished from that arising due to post processing, e.g. scratches, debris, polymer films. While certain processing effects on morphology such as those due to lapping or release etch can be controlled, the true side wall morphology appears to be governed by the morphology of the polymer mold or by the electroforming process itself, and may be much less amenable to modification.


Dutasteride is a competitive inhibitor of the enzyme 5-alpha-reductase and is commonly used to treat the symptoms of benign prostatic hyperplasia (BPH).
Objective: to determine the efficacy and safety of dutasteride in terms of indicators that are important in clinical practice.
Data sources. The literature was searched using the search terms «prostate hyperplasia», «prostate hypertrophy», «dutasteride», «quality of life», and «adverse drug reaction». Articles were obtained from Embase, PubMed, the Kokhranov Central Register of Controlled Trials, with a search till December 2020.
Study selection and data recovery. Randomized controlled trials, quasi-randomized trials, and systematic reviews evaluating the efficacy of dutasteride, both in monotherapy and in combination with alpha-blockers for the treatment of men with BPH were included in the analysis. Indicators were the need for prostate surgery, episodes of acute urinary retention, discontinuation of therapy due to side effects, the number of patients who had serious side effects, mortality and sexual dysfunction.
Data analysis. Four studies involving 1,879 patients were evaluated. All studies have shown significant clinical efficacy of dutasteride to the need for prostate surgery, with episodes of acute urinary retention that was higher than finasteride with equal safety profiles.
Conclusion. No statistically significant differences between the two 5AR inhibitors finasteride and dutasteride in terms of safety profile were found, based on the studies included in this system review. This determines the best clinical efficacy of dutasteride in terms of the number of cases of acute urinary retention and the need for surgery.


Abstract: Two new smut fungi on Ventenata (Poaceae), Tilletia elizabethae (Tilletiaceae) on V. dubia from Slovakia, and T. ventenatae on V. subenervis from Turkey, are described and illustrated. They differ from all other Tilletia species by specialization on Ventenata. Tilletia elizabethae is distinguished from T. ventenatae by having larger spores and a dark cinnamon spore mass, while the spore mass of T. ventenatae is very dark reddish brown. Citation: Denchev T. T. & Denchev C. M. 2018: Two new smut fungi on Ventenata (Poaceae): Tilletia elizabethae from Slovakia and T. ventenatae from Turkey. — Willdenowia 48: 177-183. doi: https://doi.org/10.3372/wi.48.48201 Version of record first published online on 2 July 2018 ahead of inclusion in August 2018 issue.


This paper presents a preliminary design for treatment of mining and metallurgical wastewaters (MMW) from the basin of antimony "Zajaca", which contains high concentrations of arsenic and antimony. MMW have been investigated in laboratory, due to large difference in concentrations of pollutants. Metallurgical wastewaters were treated using iron (II)-sulfate and lime milk used to adjust the pH value at 7. After chemical treatment of metallurgical wastewater and its joining with mining wastewater, residual amount of arsenic in water was below maximum allowed concentrations, while the concentration of antimony, remained above the maximum allowed value. The final phase of purification process was performed using ion exchange resin. After treatment of MMW, they can be used as technical water in the smelting process of secondary raw lead materials.


A discussion paper was developed by a panel of experts of the German Federal Environment Agency (UBA) contributing to the on-going debate on the identification, assessment and management of endocrine disruptors with a view to protect wildlife according to the EU substance legislation (plant protection products, biocides, industrial chemicals). Based on a critical synthesis of the state-of-the-art regarding regulatory requirements, testing methods, assessment schemes, decision-making criteria and risk mannvironmental hazard assessment egulatory decision making isk management agement options, we advise an appropriate and consistent implementation of this important subject into existing chemicals legislation in Europe. Our proposal for a balanced risk management of endocrine disruptors essentially advocates transparent regulatory decision making based on a scientifically robust weight of evidence approach and an adequate risk management consistent across different legislations. With respect to the latter, a more explicit consideration of the principle of proportionality of regulatory decision making and socio-economic benefits in the on-going debate is further encouraged.


Abstract : The study was conducted for the purpose of presenting information which possibly could constructively be used in motivating Air Force personnel toward increasing their levels of job performance. Several proposals were offered to assist in this objective. Although the sample used in the analysis was confined to a small group of officers (117), the authors contended that the results obtained could possibly be applied to officers throughout the Air Force. To effectively increase job performance among Air Force officers, it was suggested that Air Force leaders place added emphasis on research or study within the areas of achievement, work itself, advancement, and supervision.


A very low mass cryogenic telescope of moderate size is needed for the Space IR Telescope Facility (SIRTF). We evaluated multiple concepts for the JPL's SIRTF precursor, the 0.85 m IR telescope technology testbed with an emphasis on simultaneously achieving excellent image quality, minimum mass, and design simplicity. We selected an all-beryllium approach over one employing either silicon carbide or fused quartz mirrors. Based upon recent advances in beryllium powder metallurgy, including techniques for the reduction of residual stress, we are demonstrating that the telescope when cooled to 5 kelvins is capable of simultaneously meeting both the 6.5-micrometers diffraction-limited image quality requirement and the 30-kg mass goal. The design employs very few components and uses a single arch mirror to minimize telescope mass and simplify cryogenic mirror design, analysis, and testing. The telescope's inherently stiff metering tower combines the functions of secondary mirror support and stray light baffling. We describe the design and the trades by which we arrived at a final configuration.


Substance-related mortality rate has been increasing in the United States (US) and in various parts of the world. Analysis of drug-related death rate in the US revealed that prescriptions for the most common opioids continued to increase in 2014, accounting for 61% of drug overdose deaths among 47,055 individuals.1 Analysis of drug-related mortality for 2015 showed a decrease in methadone-related mortality, but a significant increase in heroin (a spike from 10,574 in 2014 to 12,989 in 2015) and other synthetic opioid-related mortality.2,3 The drug-related mortality rate increased from 47,055 in 2014 to 52,404 in 2015 and opioids were responsible for 60.9% and 63.0% of the mortality rate respectively in the two years. Among 51 states, death rate increased from 9.0/100,000 in 2014 to 10.4/100,000 in 2015.1


The embodiment of the present invention provides a handover opportunity configuring method, device, system and equipment, and relates to the field of network communication. The method comprises the steps of: obtaining the state of at least one terminal in a source side cell within a predetermined statistic period; determining whether to add one to the value of a current handover lateness number or not according to the state of the terminal; calculating a handover lateness ratio according to the value of the handover lateness number obtained after finish of the statistic period; and adjusting a current measuring threshold according to the handover lateness ratio. According to the present invention, the current measuring threshold is adjusted according to the handover lateness ratio, so that the problem of discapacity for adapting to various wireless environments in the prior art can be solved; link quality and service quality of each terminal in the source side cell can be obtained during each statistic period, so that adjustment of measurement/handover opportunity can be performed, thereby achieving the effects of enabling network optimization to be more intelligent by adaptively adjusting the measurement/handover opportunity.


This thesis studies profit maximizing hub location problems. These problems seek to find the optimal number and locations of hubs, allocations of demand nodes to these hubs, and routes of flows through the network to serve a given set of demands between origindestination pairs while maximizing total profit. Taking revenue into consideration, it is assumed that a portion of the demand can remain unserved when it is not profitable to be served. Potential applications of these problems arise in the design of airline passenger and freight transportation networks, truckload and less-than-truckload transportation, and express shipment and postal delivery. Firstly, mathematical formulations for different versions of profit maximizing hub location problems are developed. Alternative allocation strategies are modeled including multiple allocation, single allocation, and r-allocation, as well as allowing for the possibility of direct connections between non-hub nodes. Extensive computational analyses are performed to compare the resulting hub networks under different models, and also to evaluate the solution potential of the proposed models on commercial solvers with emphasis on the effect of the choice of parameters. Secondly, revenue management decisions are incorporated into the profit maximizing hub location problems by considering capacities of hubs. In this setting, the demand of commodities are segmented into different classes and there is available capacity at hubs which is to be allocated to these different demand segments. The decision maker needs to determine the proportion of each class of demand to serve between origin-destination pairs based on the profit to be obtained from satisfying this demand. A strong mixed-integer programming formulation of the problem is presented and Benders-based algorithms are proposed to optimally solve large-scale instances of the problem. A new methodology is developed to strengthen the Benders optimality cuts by decomposing the subproblem in a two-phase fashion. The algorithms are enhanced by the integration of improved variable fixing techniques. Computational results show that large-scale instances with up to 500 nodes and 750,000 commodities of different demand segments can be solved to optimality,


The laboratory experiment was conducted under simulated rainfalls to research into the relationship between rainfall intensity,soil slope and the sediment yield of Yimeng mountain typical slope surface.Amounts of soil erosion increased with rainfall intensity increases.The increase of rainfall intensity and slope gradient can accelerate the occurrence and changes of rills,and the sediment delivery rate is drastically increased due to the occurrence and development of the rills,and presents certain fluctuations.For the brown soil,change of slope surface is the main factor generating sediment production and erosion during a small rainfall.When the rainfall intensity strengthened,the effects caused by rainfall intensity could gradually exceed that caused by slope changing.For the cinnamon,the change of rainfall intensity is always the main factor to affect the process of desertification.When the rainfall intensity and slop were all the same,the sand generate rate and soil erosion amounts with brown soil could always exceed with cinnamon.


Objective of this research are to analyze market structure and market conduct at Kuantan Singingi area. Survey method and sample determination of this research in accordance with purposive sampling by using criteria 1-3 ha area with rubber plants life around 10-30 years. Market seller determinated by using Snow ball Sampling method with sample 48 farmer. The result, ojol market acces at Kuantan Singingi area mostly consist of  from two acces. Farmer sell the ojol through tauke and cooperative. Market structure at tauke level has oligopsoni conduct at moderate concentration with concentration rasio below 80% that is 69,69% and market structure at factory level has oligopsoni conduct at high concentration that is 84,04% and index Herfindahl value <1. Market conduct from market integrity show uncomplete, while transmition elasticity has value around 0,865 that show inelastis because it's <1 and that's show oligopsoni strength and it's caused price increment. Key words : Market Structure, Market Conduct, oligopsoni.


This article is an analytical reflection based on a personal account of working with one of India's new-generation vocational training and placement agencies implementing the government's skills policy after its revamping in 2009. As the author struggles to search for decent jobs on behalf of trained candidates, she provides insights into the state of blue-collar jobs and the troubled relationships between company 'human resources' (HR) and industrial relations (IR) managers and their workforce. While the public programmes and policies referred to here are ostensibly about skill, the article reveals them to have quite a different purpose for industry: they offer ways by which employers can not only secure the flow of casual workers but also tie them in, thereby stabilizing their workforce in an era where the 'permanent worker' is no longer an acceptable or viable category. Presenting a backdrop of moral ambiguity and dilemma, the article highlights the disconnect between the declared intent of government 'skills' policy and the way in which it is actually realized, from the viewpoint of employer, student and vocational training provider.


Abstract The phase I of [H3N(CH2)3NH3]CdI4 • 2H2O (1) crystallizes with isolated [CdI4]2-tetrahedra; monoclinic, C2/c, Z = 8, a = 1702.6(3), b= 1459.3(3), c= 1555.5(3) pm, and ß= 120.32(3)° at 299 K. (1) shows a first-order phase transition at T1↔II = 245 K. The eight 127I(v1) NQR lines in phase II change discontinuously into four lines in phase I. The transition entropy from DSC measurements, ∆S = 5.0 J K1- mol-1 , shows that this transition is probably due to order-disorder of cations. [H3CNH2(CH2)3NH3]CdBr4 (2) crystallizes with isolated [CdBr4]2- tetrahedra; orthorhombic P212121, Z = 4,a= 1447.8(5), b = 1280.3 (4), c = 709.7(3) pm at 299 K. (2) shows four 81Br NQR lines between II and around 325 K, above which temperature the lines disappear. [(CH3)4N]2CdBr4 (3) shows a second-order phase transition at T1↔II = 271 K. Three of four 81Br NQR lines in phase II disappear below this transition point, the other line can be observed up to 315 K. The transition entropy, ∆S = 9.01 J KT-1 mol-1 , indicates that the transition is an order-disorder type of the cations. [(CH3)3S]2CdBr4 (4) shows a first-order type phase transition at T1↔II = 304 K. The four lines spectrum of 81Br NQR is observed in phase II and disappears above the transition point. The transition entropy, ∆S = 46.8 J K- 1 mol-1 is abnormally large. The role of the hydrogen bond and the bridging power between the halogen and cadmium atoms upon the formation of the condensed anion structure is discussed.


In this paper, we presented a comparison between different approaches of person re-identification in camera network based on the-state-of-the-art. We studied the different descriptors of objects for identifying people and existing classifier at the re-identification step. We seek to develop video surveillance systems online in controlled areas and improve their reliability and their processing time. We concluded that using the spatio-temporal information of any person and its biometrics behavioral extracted from the video stream and analyzed then through an online classification represent a modern approach.


The steady streaming flow due to vibration in capillary bridges is considered in the limiting case when both the capillary Reynolds number and the non-dimensional vibration frequency (based on the capillary time) are large. An asymptotic model is obtained that provides the streaming flow in the bulk, outside the thin oscillatory boundary layers near the disks and the interface. Numerical integration of this model shows that several symmetric and non-symmetric streaming flow patterns are obtained for varying values of the vibration parameters. As a by-product, the quantitative response of the liquid bridge to high-frequency axial vibrations of the disks is also obtained.


This study aims to examine the challenges and opportunities UK healthcare emergency planners and responders have to cope with major hazards. The study followed a qualitative research methodology where data was collected from a comprehensive literature review, an international workshop and interviews. The findings established that the UK healthcare emergency planning process needs to: consider the integration of soft and hard resources in planning; involve independent experts for further support; and use IT systems innovatively to develop a comprehensive emergency model, predict vulnerabilities and optimise effectiveness and efficiency. The major recommendations are to: identify and evaluate risks more accurately; enhance opportunities and reduce risks associated with multiagency approaches; ensure that soft and hard resources are well integrated in planning; involve and integrate more with independent parties such as academia for extra support; and innovatively use IT systems to develop a comprehensive emergency model, predict vulnerabilities and optimise operability.


Recently, the signal processing by the three-dimensional digital filter is considered in such applications as dynamic image processing, medical image processing, robot vision, and analysis of seismic or meteorological data. This paper proposes a method of optimum design for the three-dimensional FIR digital filter using linear programming. the optimum design of the three-dimensional digital filter, including the design by linear programming, requires in general a large computational complexity. From such a viewpoint, this paper discusses the reduction of computational complexity utilizing the symmetry in the frequency response, and the result is actually applied to the design by linear programming. As a result, it is shown, for the case of the spherical lowpass filter, that the computation time is reduced by one order of magnitude by utilizing the symmetry.


The two new manuals of the National Accounts (SNA 2009) and of the Balance of Payments (IMF 2009) are implementing many new features that protract innovations firstly introduced in 1993. Among those, the paper focuses on the treatment of non financial services. The first section of the paper explains the main evolutions that the SNA sets off. Since several observers might keep in mind the old view on ser-vices (immateriality), a view that was no more endorsed by the 1993 revi-sion, primarily the paper briefly reminds the basic changes that were brought in 1993. In the second section, the paper focuses on the services versus goods is-sue and the related problems left aside, or brought in, by the revisions. The paper advocates that the contrast between goods and services, not only better holds, but becomes increasingly definite. It will be the occasion to show that the new perception borrows quite a lot from Hill's perspective (1999a). The third section of the paper is dedicated to a discussion contrasting the treatment of services in the SNA (SNA 2009) and in the BOP (IMF 2008). The aim of this comparison is to assess to what extent the two approaches have been rendered more compatible as it was intended.


Individuals with spinal cord injury (SCI) exhibit neurogenic detrusor overactivity (NDO) causing high intravesicle pressures and incontinence. The first aim was to measure changes in maximum cystometric capacity (MCC) evoked by electrical stimulation of the dorsal genital nerve (DGN) delivered either continuously or conditionally (only during bladder contractions) in persons with SCI. The second aim was to use the external anal sphincter electromyogram (EMGEAS) for real‐time control of conditional stimulation.


Fossil fuel dependence threatens environmental preservation as well as the stability of our economic and social institutions. The time is ripe for a transition away from fossil fuel over-consumption and toward renewable energy deployment. This article is an analysis of current public efforts to provide renewable energy incentives and promote wide-scale deployment. Effective initiatives require coordination between public actors and policies and a cohesive renewable energy policy strategy. Currently, governmental efforts are tangled in a complexity of actors, policies, and barriers. This analysis determines that public actors at all levels of government must work together to shape a viable and comprehensive renewable energy legal framework.


In this paper, it is analyzed the general UAVs development and their advancement with the Fifth-generation technology standard for broadband cellular networks (5G network), as well as real-time video streaming and other tools deployed for UAV use cases in the context of EU project RESPOND-A. Practically, the paper provides the case study with simulated risk realization events in which were used UAVs supported by 5G network modems, communication terminals, and 4K 360° video cameras with social viewing tools. Especially for advancing operational and surveillance capacities for SAR missions and environment protection, UAV assets are supported by the recent introduction of the 5G network, which enables a continual flow of information between them and shore-based rescue coordination centers. Such a manner would comprehend the integrated UAV data collecting capabilities, their transmission via the next generation of wireless communications, and seamless video and audio data provision, aiming to raise the level of situational awareness.


The practice of dealing indirectly (and inaccurately) with the statistical variables load and strength by using structural "factors of safety" leaves much to be desired. To help in evolving more rational methods in line with recent developments in statistics, reliability, and systems analysis, a comprehensive model is outlined. First, a cost-effectiveness model shows that optimum design is achieved when tradeoffs of weight, reliability, cost, etc., of each structural component match the system tradeoffs. Consistency of tradeoffs is ideal rather than designing all structures to the same factor of safety or reliability. The model is next enlarged to that of statistical decision theory so that uncertainties may be handled in a more reasonable way than by use of "best estimates" or "conservative assumptions." Bayesian statistical analysis is used to overcome serious problems with confidence-in-reliability formulas. Decision theory defines the best design compromise based on available information, the important deficiencies in that knowledge, and whether additional data would be worth the costs. Three examples of practical applications are briefly reviewed: 1) optimizing the weight and risk of penetration of a meteoroid shield, 2) predicting reliability of a missile part subject to fatigue, and 3) predicting reliability of a launch vehicle shell subject to buckling.


One of the products that quite popular is a nugget. It is s product that was processed by animal product. An animal product such as meat is costly and it contains a high level of fat content. One of the ways that can be used to overcome that problem is by choosing an alternative way to substitute the meat. That alternative was by using an oyster mushroom (Pleurotus ostreatus).
This research aimed to find out the effect of formulation maizena, tapioca flour and moringa leaf extract to physicochemical properties in the white oyster mushroom nuggets. This study was conducted by using Randomized Block Design (RAK) factorial with two factors. The first factor was the formulation replenishment of cornmeal and tapioca flour (10%:90%, 20%:80%, 50%:50%) while the second factor was the formulation replenishment of moringa leaf extract (1%, 2% and 3%). Parameters that were analyzed consisted of water content, fat content, fiber content, oxidant activity, vitamin C, texture, organoleptic test (elasticity, taste, color, and fondness).
 The result shows that there was an interaction between formulation replenishment of cornmeal flour with tapioca and moringa leaf extract toward water content, fat content, fiber content, oxidant activity, vitamin C, texture, weight loss, organoleptic (elasticity, taste, color, and fondness). The best treatment is A2P2 treatment (cornmeal 20%, tapioca 80% + moringa leaf extract 2%) which have antioxidant activity 33.81%, water content 57.13%, fat content 0.85%, fiber content 2.50%, vitamin C 23.82 mg/100g, texture 0.50N/mm2, weight loss 0.57g, taste score 2.33, elasticity score 3.00, color score 3.00 and panelist fondness score 3.20


Total reflection x-ray fluorescence analysis (TXRF) is an accepted powerful analytical tool for trace element determination in various kinds of samples. In typical applications like environmental, medical and technical sample analysis as well as for quality control during production processes, ultralow concentrations at the pg/g level, or femtogram masses, have to be determined. The combination of synchrotron radiation (SR) and multilayer monochromators together with TXRF is perfectly suited to meet the requirements. Best results can be expected from SR-TXRF though cost and accessability to SR sources limit the application. In some cases the additional inherent advantage of XRF as a nondestructive method is important. Another approach to reach such low detection limits is to increase the photon flux on the sample by means of high power x-ray tubes and multilayer focusing x-ray optics. With standard laboratory equipment the choice of appropriate anode materials for efficient excitation of specific elements...


The pharmacy department supply database was used to generate a summary report of volume of each anti-anginal supplied. This report with prescription audit database was used to determine the relative usage of each anti-anginal by hospitals. Two hospitals were selected and 300 consecutive anti-anginal prescriptions were recorded, analyzed. The interventional study carried out as first audit for 150 prescriptions and after given instruction to clinicians for improvement in quality of prescription writing and rationality the next 150 prescription were collected as second audit. Supply audit database at selected hospitals suggested that Nitrates, B-blockers, and Ca++ channel blockers were primary line anti-anginal drugs with relative proportional usage from supply data was 29.03%, 58.06%, 12.09% and of prescription audit data was 69.08%, 27.73%, 9.18% respectively. In first audit superscription 86.04%, inscription 54.03% subscription 1.33%, transcription 28.66%, extra point 46.33%, rationality 0.00% were present. The significant improvement as compared to first in second audit was 8.27%, 28.67%, 60.67%, 35.78%, and 14% for superscription, inscription, subscription, transcription, extra point and rationality status respectively. Out of 300 prescriptions 279 prescriptions (93.00%) were irrational based on the use of essential drug WHO and standard treatment guidelines and 207 prescriptions (74.19%) had Aspirin as concomitant drug.


Scalability is one of the Software Defined Network features that makes it more efficient than the traditional network. Due to this feature, a huge number of hosts connect to the network and require network rules and policies from the network controller. The huge number of connected hosts makes the network vulnerable to unauthorized access, which may cause network damage. In this paper, a secure hosts login technique is proposed to assure the authenticity of the hosts that need to access the network and use its resources. The proposed technique uses the key agreement protocol to allow the hosts and controller to establish secure communication. Then the procedure moves to the registration phase and login phase, which are responsible for creating and verifying the hosts' credentials while claiming network access. The secrecy and authenticity of the proposed technique was simulated, verified, and proved using AVISPA tool. The result of the simulation also proved the immunity of the proposed technique against MITM and replay attacks.


The study included titration of the Newcastle disease virus strains before preparation of the vaccines used in this experiment, by detection of EID50 for these strains. This study regarded the first one in the country in the preparation double strain oily Newcastle disease virus vaccine. The immune responses for this vaccine were compared with those of single strain NDV vaccine. The same vaccination program was used for all groups included in this study in which live attenuated )Lasota strain) vaccine given at one day old as an installation by eye and nostril, and subcutaneous injection of oily vaccine at the neck region. A total of 120 commercial broiler chicks was divided into fourth groups (1 )group vaccinated with live attenuated vaccine and bivalent (B1, Lasota ) oily vaccine while the (2)group vaccinated with live attenuated vaccine and (Lasota) oily vaccine and (3) group vaccinated with live attenuated vaccine and (AG68) oily vaccine, (4) group C was left unvaccinated as control, the Immune response for all groups was measured at ( 1) day old, (7), (14), (21), and ( 35) days old by heamagglutination test (HI) and Enzyme linked immunosorbent assay (ELISA). The results showed gradual recreation of immune response titer at 7, 14 and 21 days post vaccination intervals with non-significant differences (P> 0.05) among vaccinated groups at (7, 14) days and significant difference between vaccinated groups and control group (P>0.05) at (21) days old. The third group reflected better titer among vaccinated groups, and the result shows increased antibodies titer at (35) day in comparison with antibodies titer at (14, 21) days intervals. With statistical differences (P>0.01) among (third) group and second, and control group). However all groups gave higher titer than the control group (P>0.01) and the result of (HI) test agreement with (ELISA) test while the protection percentage were measured by challenge test, it was found to be ( 100 % ) for group (3) vaccinated with live attenuated vaccine and bivalent (B1, Lasota) oily vaccine, (92%) for the second groups (2) (96%) for the first groups (1) whereas the control group (4) gave (10%) protection. This study indicates efficacy of prepared ND vaccines (B1, Lasota) as compared with monoclonal vaccines (B1, Lasota) and the high immunosuppressive capacity of the oily vaccine increased with virulence.


Keyword: Augmented Reality Javanese Script Waterfall Educational Games Javanese script is part of the Javanese cultural heritage that is priceless, timeless, and deserves to be preserved. This script is better known as Hanacaraka. Many people have difficulty learning this Javanese script, because of its shape and the way it is written which is different from Latin script, Arabic script, or others. This study uses the Waterfall method. The stages of this waterfall method are system requirements analysis, system design, coding, program testing, program implementation and maintenance. There are many ways to introduce Javanese script to the community, especially to children, including through Augmented Reality technology. This AR technology represents real objects (real) into virtual objects in the form of 3D images, video or audio. This technology is used to introduce Javanese script in the form of educational games, so that Javanese script is more preserved and understood, especially the current millennial generation. This development is expected to be another alternative means of learning for children, as well as a means of learning for parents and educators in schools apart from books. The results of this study indicate that 60% of respondents are interested in learning Javanese script using augmented reality (AR) technology in android games compared to using book media. DOI Artikel: 10.35891/explorit.v12i2.2281 @2020 diterbitkan oleh Prodi Teknik Informatika Universitas Yudharta Pasuruan


Low- and medium-tech small and medium-sized enterprises (LMT SMEs) constitute a large and important segment in European economies. Because of increasingly international competition, LMT SMEs must rely on innovation to strengthen their competitive position over time. In this study, we empirically analyze possible complementarity or substitutability between internal capabilities and external knowledge sourcing. Using a short panel of 142 Dutch LMT SMEs, we find empirical evidence that suggests a negative interplay between internal capabilities and external knowledge sourcing.


The invention relates to an artificial breeding method for tuba false fusus, which comprises the following steps of: on the basis of investigating tuba false fusus resources along the coast of Hainan and reproductive biology, finding out the thriving propagation season of the tuba false fusus, and catching parent tuba false fusus in the season; putting healthy adult tuba false fusus into a nursery pond for intensified breeding, and optimizing breeding conditions such as water flow, illumination, water temperature, and salinity; after the tuba false fusus is mated and lays eggs, cutting off an egg capsule, and transferring to an incubation basket for flowing water breeding; after young tuba false fusus is hatched, transferring to a breeding basket, feeding concentrated chlamydomonas in first 4 to 6 days, and then feeding fresh clam and Sinonovacula constricta; when the young tuba false fusus grows to 2.0-2.5cm, dividing the young tuba false fusus; and when the young uba false fusus grows to about 4.0cm in the breeding basket, entering a culture stage. Based on the reproductive biological process of the tuba false fusus, the method realizes indoor artificial breeding of the tuba false fusus, shortens the artificial breeding cycle, is suitable for mass production, and has the advantages of simpleness, practicability, convenient operation, low production cost, and high survival rate of the bred tuba false fusus.


Christopher Snyder's gazetteer of British sites inhabited during the Arthurian era will be welcomed by Arthurians at several levels ofexpertise and research orientation; it will probably prove most useful to the informed amateur traveler, but will also serve the serious scholar specializing in other fields as a reliable checklist for rapid reference. Although far from exhaustive, its author's gift for the concise entry makes it a genuine asset. This book opens with a brief (pp. 6-13) but thoughtful discussion of the nature of archeological evidence available for this period ofmaximum transition. Part II, fourfifths of the whole, consists of more than a hundred entries from five regions of Roman Britain, classified by Snyder as the East, the Southwest (the densest, with twenty-five entries), Wales, the Midlands (only twelve entries), and the North. The longer entries (such as South Cadbury and Tintagel) each occupy on the average a full, two-column, atlas-sized page. On South Cadbury Castle, Snyder offers his readers an eighteen-item bibliography, most of it by Leslie Alcock, precisely cited in thirteen endnotes. That entry surveys with commendable dispassion the issue of that site's identification with Camelot, from John Leland to Alcock and Ashe. Unfortunately, the tamparts are cited as examples of 'murrus [sic] gallicus' construction, one of the infrequent misspellings in this carefully prepared edition. Would that the editors' care with typography had been matched by a modicum of imagination in visual design! Tintagel, the subject of Snyder's 1994 Emory Ph.D dissertation, is treated more richly. Eight authors—Ian Burrow, Kenneth Dark, OD. Morris, Jacqueline Nowakowski, Oliver Padel, C.A.R. Radford, Michael Swanton, Charles Thomas— figure in the bibliography, and Snyder's presentation of current theories—monastic centet, royal fortress, long-distance trading port—is remarkably even-handed. The numerous inevitable omissions from this selective list are occasionally regrettable. One misses some reference to the much-visited and somewhat controversial Chedworth villa, the latest wing of which has been claimed as lateRoman. The excellent discussion ofLate-Roman, Romano-British, and barely Roman Celtic evidence from Silchester, which Snyder sees as remaining the centet ofa 'Saxonfree zone' well into the seventh century, makes all the more disappointing the lack of


Objective: To explore the therapy of uplifting the upper eyelid aponeurosis on innateness ptosis.Method: Via the incision on the upper eyelid skin,orbicular muscle was cut to show the tarsi.Uplift the incision and cut the orbit to show the fat inside;then hook the fat and expose the upper eyelid aponeurosis;3 needles of mattress suture were put between the tarsi and aponeurosis,to lift the upper eyelid edge to the upper cornea edge.Result: 20 eyes(76.9 per cents) got satisfied effects;one eye(3.8 per cents) was overcorrected;5 eyes(19.2 per cents) were under-corrected.There was no serious postoperative complication.Conclusion: The operation of uplifting the upper eyelid aponeurosis is suitable for the management of mild and moderate innateness ptosis.


Abstract: Gonadectomy of male rats led to a threefold increase of 3α‐hydroxysteroid dehydrogenase (3α‐HSDH) activity in pituitary homogenates that could be completely reversed by chronic administration of estradiol or 5α‐dihydrotestosterone (DHT). 3α‐HSDH was found to be distributed mainly between the 10,000 g and 100,000 g sediments from whole homogenates. The microsomal enzyme activity showed a substantial specificity for NADH whereas the cytosolic enzyme (100,000 g supernatant) demonstrated a slight preference for NADPH. The changes in Vmax found in homogenates following gonadectomy and gonadal steroid administration reflected changes in NADH‐ linked activity of the microsomal, but not the cytosolic enzyme. Estradiol‐induced suppression of NADH‐linked 3α‐HSDH activity in pituitary homogenates from gonadectomized rats of either sex was accompanied by a similar suppression of NADPH‐linked 5α‐reductase activity and a marked decrease of luteinizing hormone (LH) and follicle‐stimulating hormone (FSH) release. In the ovariectomized rat chronic administration of nonsteroidal antiestrogens had strong estrogenic effects on 3α‐HSDH activity and LH release, but not on 5α‐reductase activity and FSH release. In the gonadectomized male rat, which was much less sensitive to intrinsic estrogenicity of the antiestrogens tested, nafoxidine completely blocked estradiol‐induced suppression of 5α‐reductase activity and FSH release and partially antagonized suppression of LH release. The trans‐isomeric, substituted triphenylethylenes, tamoxifen, and enclomiphene, as well as nitromifene (mixture of trans and cis isomers) were able partially to counteract estradiol‐induced suppression of 5α‐reductase, but not 3α‐HSDH activity. It is concluded that estradiol action on pituitary 5α‐reductase, but not 3α‐HSDH activity, involves an estrogen receptor mechanism.


This paper presents a contribution for air temperature measurement inside buildings. The objective is to show the influence due to long wave radiation in the measurement and that this effect can be minimized by a protection with a good radiant barrier. This protection can be made by using a PET bottle enveloped by aluminum paper, which has the effect of a barrier for long wave radiation. It was also possible to prove that the metallic globe of the globe thermometer can be replaced by a plastic globe material, without alteration on the results.


In this paper, we evaluate LSTM, biLSTM, GRU, and Transformer architectures for the task of name transliteration in a many-to-one multilingual paradigm, transliterating from 590 languages to English. We experiment with different encoder-decoder combinations and evaluate them using accuracy, character error rate, and an F-measure based on longest continuous subsequences. We find that using a Transformer for the encoder and decoder performs best, improving accuracy by over 4 points compared to previous work. We explore whether manipulating the source text by adding macrolanguage flag tokens or pre-romanizing source strings can improve performance and find that neither manipulation has a positive effect. Finally, we analyze performance differences between the LSTM and Transformer encoders when using a Transformer decoder and find that the Transformer encoder is better able to handle insertions and substitutions when transliterating.


A close examination of biblical theophany narratives reveals the existence of a fixed set of elements. The use of the rubric "theophany narrative" allows for a better understanding of the literary dynamics of these texts than the form-critical model, which is usually applied to these stories. As a result, texts that have been traditionally grouped according to a variety of genres—call narratives, annunciation stories, dream reports—are here treated together. This study identifies the following distinct stages in these narratives: (1) separation from society; (2) visual and verbal encounter with the divine; (3) human response to the encounter, ranging from fear to skepticism; and (4) externalization of the experience. Insofar as each of these stages displays a range of literary strategies that highlight the unique concerns of the particular narrative, a type-scene model proves to be most useful as an interpretive key for these texts.


A transient energy analysis was performed in a Compressed Air Energy Storage (CAES) system. The aim is to perform a parametric analysis to determine the efficiency and output energy depending on some design parameters as the number of tanks connected in parallel, the insulation thickness, the storage time and the outflow. Mass and energy balances were carried out on every component of the system, the resulting equations from the analysis were solved numerically using the explicit Euler's method. The system operating for a short storage time presents a higher efficiency (about 42.38%) with insulated tanks, however it is lower (about 23.54%) for long storage time and non-insulated tanks. Nevertheless, when the system with insulated tanks reaches the steady state, i.e., for long storage time, its efficiency is almost half that one with tanks without insulation, 11.5% and 23.54%, respectively. These results indicate that for short storage times is better to insulate the tanks and for longer storage times is more convenient no insulation.  Article DOI:  https://dx.doi.org/10.20319/mijst.2017.32.145164 This work is licensed under the Creative Commons Attribution-Non-commercial 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc/4.0/ or send a letter to Creative Commons, PO Box 1866, Mountain View, CA 94042, USA.


Touch is a sense with which humans are able to actively explore the world around them. Primary somatosensory cortex (S1) processing has been studied to differing degrees at both the macroscopic and microscopic levels in both humans and animals. Both levels of enquiry have their advantages, but attempts to combine the two approaches are still in their infancy. One mechanism that is possibly involved in determining the reponse properties of neurons that are involved in sensory discrimination is inhibition by γ-aminobutyric acid (GABA). Several studies have shown that inhibition is an important mechanism to "tune" the response of neurons. Recently it has become possible to measure the concentration of GABA in vivo using edited Magnetic Resonance Spectroscopy (MRS), whereas magnetoencephalography (MEG) offers the possibility to look at changes in neuromagnetic activation with millisecond accuracy. With these methods we aimed to establish whether in vivo non-invasive neuroimaging can elucidate the underlying neuronal mechanisms of human tactile behaviour and to determine how such findings can be integrated with what is currently known from invasive methods. Edited GABA-MRS has shown that individual GABA concentration in S1 correlates strongly with tactile frequency discrimination. MEG was used to investigate the neuromagnetic correlates of a frequency discrimination paradigm in which we induced adaptation to a 25 Hz frequency. We showed that S1 is driven by the adapting stimulus and shows that neural rhythms are modulated as a result of adaptation. This is the first time that behavioural psychophysics of tactile adaptation has been investigated using complimentary neuroimaging methods. We combined different methods to complement both physiological and behavioural studies of tactile processing in S1 to investigate the factors involved in the neural dynamics of tactile processing and we show that non-invasive studies on humans can be used to understand physiological underpinnings of somatosensory processing.


Subtitle: With airlines looking to cut costs, how great a threat are PMA part makers becoming to original equipment manufacturers' profit margins?


Background: Vaccine schedules including bivalent oral and inactivated poliovirus vaccines will replace trivalent oral poliovirus vaccines in 2016. Methods: We evaluated rotavirus immunoglobulin A seroresponses when the second dose of Rotarix at 16 weeks was given concomitantly with inactivated or bivalent oral poliovirus vaccines. Results: Rotavirus immunoglobulin A seroresponse rate at week 28 was 15% lower in recipients of bivalent oral poliovirus vaccines compared with inactivated poliovirus vaccines. Conclusion: Bivalent oral poliovirus vaccine decreases rotavirus IgA seroresponse rates when coadministered at 16 weeks of age.


Objective:To explore the situation of getting free contraceptive among the floating population including source and types of free contraceptive,its risk factors and its obstacle.Methods:During March to August 2007,a study under the adoption of questionnaires was conducted among 2 849 floating population,who didn't use the IUD currently and were in reproductive age,random selected from two family planning centers in Shenzhen.Results:61.5% floating population reported that the family planning service centers was the main source of getting free contraceptive and the second was the community workstation(22.3%),most of the floating population(95.4%) for the condom Multiple factor analysis showed that population from urban area(χ2=7.904,P=0.006),unmarried population(χ2=435.410,P=0.000),before 25-year-old(χ2=216.795,P=0.000),white collars(χ2=161.759,P=0.000)and income less than 1 000 Yuan(χ2=41.583,P=0.000)had relation to getting free contraceptives or not.The floating population feel embarrassing(nearly 40%) was the main obstacle of getting free contraceptive and the second was inconvenience(33.7%).Conclusion:The most of floating population get free contraceptive from the family planning service centers.The rate of getting free contraceptive among the floating population who are from urban area,unmarried population,before 25-year-old,white collars and income less than 1 000 Yuan is relative low,and they feel embarrassing which is the main obstacle;It's showed that the family planning facilities need to provide the directed and individual service of free contraceptive to floating population.


Acid-insoluble lignin can be hardly analyzed by spectroscopy because of the insoluble character in all organic solvents, and hence its chemical characteristics are not sufficiently clarified. To know the lignin content and the carbohydrate composition in pulps and woods, standard methods : JIS, Japan TAPPI, and TAPPI methods have been used, but different conditions for acid hydrolysis are chosen in these methods. It is required that conditions for acid hydrolysis are modified to shorten the time for determining the lignin content and the carbohydrate composition in many samples. To characterize the acid-insoluble residues prepared under various acid-hydrolysis conditions, pyrolysis-gaschromatography (Py-GC) is expected to be effective. In this paper, chemical characteristics of acid-insoluble lignins were discussed using Py-GC in order to find an improved method for determining the lignin content and the carbohydrate composition. The treatment period of the primary acid hydrolysis with 72% sulfuric acid should be at least 2.5 hours for analyzing lignin and carbohydrate composition in pulps and wood meals. If it is less than 1 hour, acid hydrolysis of cellulose is not sufficient, and in this case, it is in dicated by the pyrogram of the acid-insoluble residue that there are some


Purpose: The purpose of this study is to examine the relationship between social proof and a company's profitability, with a specific focus on the case of Vichy. Fear of Missing Out (F.O.M.O.) is a psychological phenomenon social proof trigger. The study emphasises the significance of social proofing, a marketing strategy that analyses consumer preferences and behaviours. Methodology: The research paradigm used in this study is positivism, with a deductive approach. The sample size is made up of fifty employees from the company. To achieve the best research results, both quantitative and qualitative research methods were used. In-depth interviews were conducted with two Vichy managers to understand better the use of social proof to boost company performance. Findings: The study demonstrates organisational growth and profitability through social proofing in a competitive business environment. As a result, it comprehends current organisational conditions and emphasises business expansion in the digital business economy. Furthermore, the ANOVA test indicates that there is an existence of a direct or indirect relationship between social proof and brand profitability. Study originality and implications: To attract customers and increase profits, U.K. skincare retailers widely use social proofs such as case studies, customer reviews, awards, and influencer marketing. Companies can easily reach their target audience by using this marketing technique. However, there has been little or no research in this area, particularly in a luxury brand like Vichy. As a result, the findings are highly original, with significant academic and organisational implications. Companies can use the findings to implement effective social-proof marketing strategies to increase profits.


In this work we investigate the coherent photoproduction of psi(1S), psi(2S) and Upsilon (1S) states in the proton-nucleus collisions in the LHC energies. Predictions for the rapidity distributions are presented using the color dipole formalism and including saturation effects that are expected to be relevant at high energies. Calculations are done at the energy 5.02 TeV and also for the next LHC run at 8.8 TeV in proton-lead mode. Discussion is performed on the main theoretical uncertainties associated to the calculations.


Purpose – This paper seeks to point outs that, when managing strategically, a library administrator might want to use cost-benefit analysis to prudently spend money and, consequently, would need to understand this methodology. Design/methodology/approach – The paper discusses the various types of cost-benefit analysis and provides examples of their use. Findings – It is helpful for library managers to have a proper knowledge of cost-benefit analysis. Practical implications – This provides one methodology that librarians should consider when contemplating what purchases to make. Originality/value – This article will help librarians better manage their libraries by making them aware of cost-benefit analysis.


On November 2011, the revised Korean Commercial Code (hereinafter "the Law") has been effected and it contains new additional Chapter for...


Abstract Background: Development of many techniques conserve blood in cardiac surgery has been established, to avoid the side effects of homologous blood transfusion. One of these techniques is the Retrograde Autologous Priming (RAP); which is a blood conservation technique designed to decrease the severity of hemodilution during cardiopulmonary bypass and thus decreasing perioperative transfusions. Aim of Study: The aim was to examine the safety and efficacy of RAP and its role in decreasing adverse outcomes on body systems after cardiac surgery. Patients and Methods: This work was performed on 60 adult patients indicated for open heart surgery as valvular heart disease or coronary heart disease. 30 patients were operated using RAP technique and 30 patients using ordinary priming method of cardiopulmonary bypass (CPB). Results: The CPB mean time was significantly shorter in the RAP group. The hemoglobin (Hb) level and hematocrit (Hct) concentration in the perioperative and postoperative time as significantly higher in the RAP group also the platelet count was significantly higher in the RAP group (p 0.05) between the two groups. Conclusions: RAP is an efficient and economical method in limiting the amount of priming volume of the CPB system, causing less hemodilution, reducing intra- and postoperative blood transfusion and decreasing adverse effects of hemodi-lution on body systems.


LAND ECONOMICS STUDY INFORMATION NEEDS TO BE READILY AVAILABLE FOR USE AS COMPARABLES TO PROVIDE ADEQUATE BUT NOT EXCESSIVE PAYMENTS FOR HIGHWAY RIGHT-OF-WAYS. THESE COMPARABLES ARE ORDINARILY PROVIDED BY STATE HIGHWAY DEPARTMENTS. FOR UNUSUAL TYPE CASES OR FOR STATES IN THE INITIAL STAGES OF LAND ECONOMIC STUDIES, THE BUREAU OF PUBLIC ROADS MAY BE ABLE TO ASSIST IN LOCATING COMPARABLES, EITHER THROUGH THE BANK OF CASES RECORDED AND MAINTAINED BY EDP OR BY MEANS OF AN INDEX OF NARRATIVE REPORTS WHICH IS BEING UPDATED. A FEW GENERAL CONCLUSIONS ARE MADE FROM ANALYSIS OF THESE RECORDED CASES' /1/ LAND VALUE INCREASES HAVE OCCURRED IN ABOUT FOUR CASES OUT OF FIVE, /2/ CERTAIN CHARACTERISTICS ASSOCIATED WITH HIGHER-THAN-AVERAGE LAND VALUES ARE NEARNESS TO AN INTERCHANGE, AND LAND USED FOR COMMERCIAL PURPOSES, ESPECIALLY IN THE PERIOD AFTER THE RIGHT-OF-WAY TAKING, /3/ MOST LANDLOCKED PARCELS HAVE NOT EXPERIENCED THE HEAVY DAMAGES ANTICIPATED WHEN SETTLEMENT WAS MADE, AND /4/ OWNERS OF VACANT PROPERTIES APPEAR MORE LIKELY TO EXPERIENCE GAINS THAN OWNERS OF RESIDENTIAL OR AGRICULTURAL PROPERTIES.


We carried out the determination of prooxidant and antioxidant activity of peritoneal and broncho-alveolar lavage fluid in 60 male rats Wistar, which had been previously subjected to general hyperthermia once. The shift of equilibrium in the system «prooxidants antioxidants» in the direction of prooxidant has been revealed at determining of proand antioxidant activity ratio. It testifies to the development of oxidative stress in posthyperthermic period.


George Macdonald. Note on some fragments of Imperial statues and of a statuette of Victory. H. Stuart Jones. Claudius and the Jewish Question at Alexandria. Felix Oswald. The pottery of a third-century well at Margidunum. H. M. D. Parker. A note on the promotion of the centurions. W. H. Buckler, W. M. Calder and C. W. M. Cox. Asia Minor, 1924. III. A. H. Smith. A military diploma. W. M. Ramsay. Studies in the Roman Province Galatia.


By using quasi birth and death process and matrix-geometric solutions,the M/M/c queue with single asynchronous vacation of partial servers was considered.Some computational methods for stable indices and results of conditional stochastic decompositions were given.


With high frequency of "pass by on the other side" incidents in China,people start to argue about whether those who "pass by on the other side" have obligations to rescue in need and whether "pass by on the other side" behavior should be incriminated in Criminal Law if this is tenable.Legally,"Pass by on the other side" behavior is duly in accordance with Roll's view of fair and just and possesses the legal basis of incrimination,so the accusation of "pass by on the other side" should be established in China,and it should be recognized as the crime when in keeping with the four constitutive elements of crime simultaneously.Also,those who "pass by on the other side" should be punished according to law.


The Ligatus research unit of the University of the Arts, London has undertaken the recording of the binding structures and materials of the manuscripts and early printed books from the library of the Saint Catherine Monastery in Sinai, Egypt. Conservators from many different countries have been engaged in both the examination of the books and the formation of a recording methodology for binding structures. About 4500 books have been examined one by one. The detail with which the recording was done resulted in a large amount of information about each book's individual components. Organising this information has been a challenging task and a variety of data structuring models were assessed for storing the collected data. Our assessment showed that hierarchical data structuring is an efficient way to record binding information. In this paper, a recording methodology with XML hierarchies is presented, based on the experience from the Saint Catherine's collection.
The root of the hierarchy represents the concept of the specific book being recorded and the rest of the binding components are mapped as developing branches from the root. The hierarchy offers an "infinite" number of developing branches allowing space for every piece of information about the material or structure of the book. The hierarchy acts both as a storage system for the observations and as a consistency checking mechanism which ensures that the recorded information is complete and, to a certain extent, correct. XML is a good tool for implementing hierarchies with many additional benefits. These include the long-term preservation of the recorded data, the great potential for multilingual implementations and the good support by almost all major programming languages.
The proposed methodology has successfully been tested at the Saint Catherine's library collection, and it is proved ready to be tested on other collections.


Objective To study the change of c-myc gene expression in thymic lymphomas of mice induced by ionizing radiation and provide theoretical basis for mechanism of radiation carcinogenesis.Methods The thymic lymphomas models of BALB/c mice were made by X-ray(dose rate:0.287 Gy·min-1;total dose:7 Gy) exposuring,6 months later they were killed,then total RNA and total protein were extracted from thymic lymphomas and normal thymus tissue and cDNA was synthesized,the expressions of c-myc mRNA and protein in thymic lymphomas induced by ionizing radiation and normal thymus were detected by quantitative real-time PCR and Western blotting respectively.Results The expression of c-myc mRNA in thymic lymphomas(9.16±4.66) was higher than that in normal thymus tissue(1.16±0.54)(P0.01). The expression of c-myc protein in thymic lymphomas was higher than that in normal thymus tissue. Conclusion There is relevance between c-myc gene and thymic lymphomas induced by ionizing radiation,c-myc gene might be susceptibility gene of radiation carcinogenesis.