System for the transmission of pulse streams, wherein the transmission devices comprise a main or master transmission device (100) and secondary transmission devices or stations (20-36), said master transmission device (100) and said stations (20-36) each having their own address, the pulses transmitted by said system being controlled by a communications protocol having at least one frame (D-F) including at least the address (Sd) of the information destination station and the address (Sr1, SR2) of the station relaying the information. The transmission devices are arranged so that each transmission device is capable of receiving information from another transmission device and retransmitting said information to another transmission device, each transmission device including means for interrupting its receiving function as soon as the transmission function is operational. Said stations (20-36) are geographically arranged in chains branching out from the master transmission device (100), each chain including at least one main branch (1-15), said main branches (1-15) being placed in a star configuration around the master transmission device (300), said frame (D-F) also including the address (Se) of the station sending the information.


Traditionally, consumer preference is modeled in terms of preference for the aesthetic and functional features of a product. This paper introduces a new means to model consumer preference that accounts for not only for how a product looks and functions but also how it feels to interact with it. Traditional conjoint-based approaches to preference modeling require a participant to judge preference for a product based upon a static 2D visual representation or a feature list. While the aesthetic forms and functional features of a product are certainly important, the decision to buy or not to buy a product often depends on more, namely, the experience or feel of use. To address the importance of the product experience, we introduce the concept of experiential conjoint analysis, a method to mathematically capture preference for a product through experience-based (experiential) preference judgments. Experiential preference judgments are made based upon the use, or simulated use, of a product. For many products, creating enough physical prototypes to generate a preference model is cost prohibitive. In this work, virtual reality (VR) technologies are used to allow the participant an interactive virtual product experience, provided at little investment. The results of this work show that providing additional interaction-based (interactional) information about a product through a product experience does not affect the predictive ability of the resulting preference models. This work additionally demonstrates that the preference judgments of virtual product representations are more similar to preference judgments of real products than preference judgments of 2D product representations are. When examining similarity of modeled preference, experiential conjoint is found to be superior to visual conjoint with respect to mean absolute error (MAE), but with respect to correlation no significant difference between visual and experiential is found. [DOI: 10.1115/1.4027985]


The present invention relates to a method for preparing a polymorph form A of N-(S)-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide that exhibits a powder x-ray diffraction pattern comprising at least 50% of the peaks identified in the powder x-ray diffraction pattern shown in Fig. 5, comprising crystallizing amorphous N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide from a mixture of heptane and ethyl acetate to obtain said polymorph. The present invention also relates to a pharmaceutical composition that comprises said compound and to a method of the treatment of a MEK mediated disorder using a crystalline polymorph of N-(S)-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide that possesses at least one of the following properties: (a) exhibits the powder x-ray diffraction pattern substantially the same as the powder x-ray diffraction pattern shown in Fig. 5 for said crystalline polymorph, (b) exhibits a differential scanning calorimetry pattern substantially the same as the differential scanning calorimetry pattern shown in Fig. 6 for said crystalline polymorph, or (c) has a melting point onset as determined by differential scanning calorimetry at about 143°C.


Two iso-singlet hadron states $X_0(2900)$ and $X_1(2900)$ with $J=0$ and 1 respectively, discovered by the LHCb collaboration in 2020, were identified as molecular bound states of $\bar D^*K^*$. Recently two structures $T^a_{cs0}(2900)^0$ and $T^a_{cs0}(2900)^{++}$ have been observed at the hadron spectra, one would suspect if they also are molecular states of $D^*$ and $K^*$. As long as they were of the molecular structures of $D^*K^*$, the hadron states must be in an iso-vector, namely $T^a_{cs0}(2900)^0$ and $T^a_{cs0}(2900)^{++}$ were $I_3=-1, 1$ components of the iso-vector. If it is the case, the corresponding $T^a_{cs0}(2900)^+$ of ($I=1,I_3=0$) and $T^{'a}_{cs0}(2900)^{+}$ of $I=0,I_3=0$ so far evade experimental observation, but should be found by the future experiments. To testify this ansatz, in this paper we study the possible molecular structures of $\bar D^{*}K^{*}$ and $D^{*}K^{*}$ within the Bethe-Salpeter (B-S) framework. With reasonable input parameters it is found that $\bar D^{*}K^{*}$ iso-scalar systems with $J^P=0^+$ and $1^+$ are solutions. The result supports the ansatz of $X_0(2900)$ ($X_1(2900)$) being molecular states of $\bar D^*K^{*}$. Whereas for the system of $ D^{*}K^{*}$ with $I=1$ the corresponding B-S equation has no solution. Thus we can draw a clear conclusion that $T^a_{cs0}(2900)^0$ and $T^a_{cs0}(2900)^{++}$ should not be bound states of $ D^{*}$ and $K^{*}$. The two structures observed by the LHCb collaboration may be caused by dynamics, such as the well-recognized triangle anomalies or other mechanisms.


The application of convolution neural networks (CNN) to image super-resolution has achieved excellent results. Inspired by these excellent results, we find that most models only increase the depth of the network in order to obtain deeper features. However, these models often cannot take full advantage of the original feature information from the low-resolution (LR) images. Moreover, the image information is mainly divided into high frequency information and low frequency information, and the existing image super resolution network models are mostly single-branch models, which limits the performance of extracting various aspects of image information. To resolve the problem, we proposed a parallel net work model. About the network, we proposed the LR residual block (LRB) and attention block (AB). LRB allows constantly replenishing original LR features in the process of extracting deep features, thus it can effectively extract more information from LR image. The AB contains the attention mechanism, it will ad just their weights based on the importance of the image features to extract more efficient features between low- resolution (LR) images and high-resolution (HR) images. Experiments on benchmark datasets show that our model performs better. We achieve higher accuracy and visual improvements against state-of-the-art methods.


This paper presents a study that investigate the effects of children, household and state factors on primary school non-attendance among children in North West Nigeria. The study uses a nationally representative dataset, the Nigerian Education Data Survey (NEDS 2010) to investigate how children, household and state factors affect primary school non-attendance among children. The data pertaining to the area under study was extracted from the NEDS 2010 dataset and prepared for analysis. The study then uses multilevel analysis to hierarchically examine the effects of children, household and state factors on primary school non-attendance in North West Nigeria. The results of the multilevel analysis showed that most of the strong determinants of primary school non-attendance was due to household factors, with parental education and wealth being the most important. The results further showed that parental education and wealth also influences other factors across children, household and state levels. The results also showed that distance to school has more influence on primary school non-attendance among state factors.


The paper presents the experimental verification of a general mathematical model of Voltage Source Inverters (VSI) able to simulate fault conditions and which is also useful for the simulation of fault-tolerant systems for different applications. In general, in the past, the problem of faulty inverters modeling has been addressed specifically by considering faults on the different phases as separate cases. Furthermore, traditional models include only the faulty mode and not the healthy mode, so resulting then not able to predict transient phenomena. The model hereafter presented overcomes this drawback. It was formulated by introducing the concept of "healthy leg binary variables". Such variables allow the management of both unfaulted and faulted conditions regardless of what is the faulty phase. Experimental tests were used to verify the correctness of the followed modeling approach and the ability of the model to predict transients before, during and after the application of a fault tolerant control.


IdlB and IdlC are two previously isolated classes of CHO cell mutant, with LDL receptor deficiencies and broad glycosylation defects. These mutant cells exhibit a broad set of defects in processing reactions within the Golgi apparatus, affecting virtually all Nand O-linked glycoproteins, and glycolipids. The LDL receptor deficiency in IdlB and IdlC cells is a secondary consequence of the Golgi processing defects. I have conducted a molecular analysis of IdlC mutant cells, to determine how a single defect can affect multiple reactions within the Golgi. I have cloned by complementation a human cDNA (LDLC) that fully corrects the mutant phenotypes when transfected into IdlC cells. The LDLC cDNA did not correct the apparently identical mutant phenotypes in IdlB cells. By Northern blot analysis, the endogenous LDLC mRNA was clearly expressed in wild-type CHO cells but not in IdlC mutant cells, suggesting that the LDLC cDNA is a normal human counterpart to the defective gene of IdlC cells. The LDLC cDNA was shown by sequence analysis to encode a protein (IdlCp) that was not similar in sequence to other known proteins. IdlCp has a predicted size of 83 kilodaltons, and contains no common structural motifs such as transmembrane domains or translocation signal sequences. Site-directed mutations introduced into the LDLC cDNA indicated that an amino-terminal portion of IdlCp may be dispensable for function. A cDNA related to the human LDLC cDNA was cloned from Caenorhabditis elegans, to extend the LDLC sequence analysis. It encodes a distant homolog of IdlCp, indicating that IdlCp mediates conserved cellular functions. This cDNA was physically mapped within the Caenorhabditis elegans genome, and several genetic loci were identified as LDLC candidates. Antibodies were raised against IdlCp, and used for immunofluorescence localization studies. In wild-type CHO cells, IdlCp colocalized with Golgi markers. Localization was disrupted by short treatment with the drug brefeldin A, which dissociates known peripheral proteins such as betaCOP from the Golgi. In IdlB cells, IdlCp was expressed at normal levels but was not localized to the Golgi. Together, these results demonstrate that IdlCp is a peripheral Golgi protein that requires the putative LDLB gene for Golgi localization. Thesis Supervisor: Dr. Monty Krieger Title: Professor of Biology


Disclosing a kind of is used to controlling starting the method that circulates of defrosting with the refrigerated transport container operationally evaporator heat exchanger of related refrigeration system.The method comprising the steps of:Set up that returning air saturation temperature is poor, the returning air saturation temperature difference is equal to the difference that the sensing air themperature for returning to the air stream flowed through on the heat exchange surface of the evaporator heat exchanger from the container subtracts the refrigerant saturation temperature by the cold-producing medium stream of the evaporator heat exchanger;Returning air saturation temperature difference is compared with set point threshold value defrosting temperature difference;And in the case where returning air saturation temperature difference exceedes set point threshold value defrosting temperature difference, start the defrosting for the evaporator heat exchanger to be defrosted and circulate.


Surveying and Mapping System usually has a lot of images to process and Out-door Image Collection System calls for high realtime performance. The result of digital image processing tests on GPU and CPU showed that the performance of digital image processing could be greatly improved by GPU-based parallel computing. GPUbased parallel computing can increase the speed of image pre-processing and image post-processing so that the Surveying and Mapping System becomes more efficient and has high real-time performance.


A case of one-stage free rectus abdominis myocutaneous flap was reported. The patient was a 68 year old male with a very small primary cancer lesion in the right molar region of the mandible.However, the X-ray films at first visit (30-9-1988) showed abnormal figure.He was clinically diagnosed as mandibular cancer (T3N0M0). He had taken radiotherapy of Linac 2, 000 rads from June 13th to June 24th before operation.In as much as cervical lymph node metastasis was absent, we decided to operate on the mandibular cancer lesion.We used a free rectus abdominis myocutaneous flap to replace the loss of the mandible and the mouth floor.The mouth floor and the mandible were resected continuously at the 8-3 portion (and the mouth floor) and an upper neck dissection was performed.An A-O plate and a free abdominis myocutaneous flap was put in place in the mouth to close the defect.The flap was revascularized by anastomosing the inferior epigastric artery and vein to the facial vessels. The flap being well revascularized, no functionary morbidities occurred after its replacement. A denture was constructed after 6 months. The prognosis for this case is satisfactory. The main characteristics of this flap are as follows:(1) The flap is very easily and quickly elevated with the patient in a supine position.(2) In many cases flap elevation and oral cancer surgery can be performed simultaneously, thereby reducing operating time.(3) There are very few anatomical variations in the deep inferior epigastric vessels.


. The increase of volatile organic compounds (VOCs) emissions released into the atmosphere is one 17 of the main threats to human health and climate. VOCs can adversely affect human life through their 18 contribution to air pollution directly and indirectly by reacting via several mechanisms in the air to form 19 secondary organic aerosols. In this study, aerial drone equipped with miniaturized air sampling systems 20 including up to four solid-phase microextraction (SPME) Arrows and four in-tube extraction (ITEX) 21 samplers for the collection of VOCs, along with portable devices for the real-time measurement of black 22 carbon (BC) and total particle numbers at high altitudes was exploited. In total, 135 air samples were collected 23 under optimal sampling conditions in October 2021 at the boreal forest SMEAR II Station, Finland. A total 24 of 48 different VOCs, including nitrogen-containing compounds, alcohols, aldehydes, ketones


The prevalence of cystic fibrosis‐related diabetes melltitus (CFRD) is increasing as patients with cystic fibrosis (CF) live longer. Because patients with CFRD are insulin‐deficient, the standard medical treatment is exogenous insulin. Sulfonylureas enhance insulin secretion by acting on a specific islet beta cell receptor. No data are available about the outcome of sulfonylurea treatment vs. insulin treatment. In this retrospective study, data from 45 patients with CFRD were analyzed regarding their clinical outcome as it related to the treatment protocol.


The studies were fulfilled using the theories of ecology and ecological recovery based on the analyses of composition and system of vegetation in Ledu county.It was concluded that the vegetation of woodland and meadow could be recovered by the approaches of recovery forest using local species,enclose the hills for natural forestation,rain-gathered and forest planted,forestation by imitation the autogenic succession and run-off forestry.


We present experimental results of harmonic generation using a 1-ps 1015-W/cm2 Nd-glass laser. We see up to the 29th harmonic in Xe, 57th in Ar, and at least up to the 135th harmonic in Ne (160 eV), being then limited by our monochromator's resolution. The conversion efficiencies in Xe, Ar, Ne, and He are compared and different ways of optimizing the number of photons by defocusing the laser beam or increasing the density are discussed.


The nonisothermal crystallization kinetics of linear Poly(phenylene sulfide) (PPS) was studied with differential scanning calorimetry. Ozawa theory, Jeziorny model, and Mo equation were applied to describe the crystallization kinetics and to determine the crystallization parameters and mechanism of the linear PPS resin. The crystallization activation energies were also calculated using Kissinger formula and Flynn-Wall-Ozawa equation, respectively. According to the Ozawa model, it is found that instantaneous nucleation takes place during crystallization of PPS; the Ozawa exponent m is 3 in initial stage of crystallization; as the crystallization temperature decreases, the value of m reduces, and the growth rate of crystal almost keeps a constant. The Avrami exponent n obtained from Jeziorny model fluctuate around 1.84. Based on the Jeziorny model, the crystallization rate increases with increasing the cooling rate, but it does not change any longer when the cooling rate rise to a certain value. Mo equation also exhibits great advantages in treating the nonisothermal crystallization kinetics of PPS. The activation energy E of nonisothermal crystallization process of PPS is calculated to be −162.73 kJ/mol by the Kissinger formula, and the mean value of E determined by Flynn-Wall-Ozawa equation is −152.40 kJ/mol. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011


Extensive losses of coastal wetlands in the United States caused by sea-level rise, land subsidence, erosion, and coastal development have increased hterest in the creation of salt marshes within estuaries. Smooth cordgrass Spartina altemiflora is the species utilized most for salt marsh creation and restoration throughout the Atlantic and Gulf coasts of the U.S., while S. foliosa and Salicomia virginica are often used in California. Salt marshes have many valuable functions such as protecting shorelines from erosion, stabilizing deposits of dredged material, dampening flood effects, trapping water-born sediments, serving as nutrient reservoirs, acting as tertiary water
treatment systems to rid coastal waters of contaminants, serving as nurseries for many juvenile fish and shellfish species, and serving as habitat for various wildlife species
(Kusler and Kentula 1989). The establishment of vegetation in itself is generally sufficient to provide the functions of erosion control, substrate stabilization, and sediment trapping. The development of other salt marsh functions, however, is more difficult to assess. For example, natural estuarine salt marshes support a wide variety of fish and shellfish, and the abundance of coastal marshes has been correlated with fisheries landings (Turner 1977, Boesch and Turner 1984). Marshes function for aquatic species by providing breeding areas, refuges from predation, and rich feeding grounds (Zimmerman and Minello 1984, Boesch and Turner 1984, Kneib 1984, 1987, Minello and Zimmerman 1991). However, the relative value of created marshes versus that of natural marshes for estuarine animals has been questioned (Carnmen 1976, Race and Christie 1982, Broome 1989, Pacific Estuarine Research Laboratory 1990, LaSalle et al. 1991, Minello and Zimmerman 1992, Zedler 1993). Restoration of all salt marsh functions is necessary to prevent habitat creation and restoration activities from having a negative impact on coastal ecosystems.


The invention relates to a simulation modeling method for liquid-solid two-phase flow in a desulfurization system of a thermal power plant. The method comprises: S1, establishing an equivalent physical model of the liquid-solid two-phase flow in the desulfurization system of the thermal power plant; S2, selecting process parameters of the desulfurization system of the thermal power plant as input variables of the equivalent physical model; S3~S5, according to the input variables and the preset desulfurization efficiency, calculating equilibrium hydrogen ion concentration in a slurry tank and sulfur dioxide mole fraction in circulating slurry to further obtain the desulfurization efficiency; and S6, if the desulfurization efficiency is not consistent with the preset desulfurization efficiency, setting the desulfurization efficiency to be the preset desulfurization efficiency, performing the steps S3~S5, and setting the equivalent physical model to be a simulation model for the liquid-solid two-phase flow in the desulfurization system of the thermal power plant until the desulfurization efficiency reaches the preset desulfurization efficiency. The method can provide nondestructive experimental data for technicians, reflect an actual operational situation of the desulfurization system of the thermal power plant accurately in real time, and provide a reference basis for perfection of the desulfurization system of the thermal power plant.


The invention relates to a multi-strain microorganism pig feed additive and a production method thereof. According to the additive, bacillus subtilis, lactobacillus delbrueckii, saccharomyces cerevisiae, candida and photosynthetic bacteria are inoculated into a fermentation culture medium according to a ratio of 2:1:1:1:2, and are prepared into a finished product through solid fermentation. The microorganism preparation is reasonably matched, various microorganisms in the preparation can bring respective effects into play and depend on one another, the overall advantage of the microorganism preparation can be brought into play, the growth development and the improvement of the anti-disease capability of a host are facilitated, and the feed additive is safe to use and can improve the immunity of animals, prevent and resist diseases, prompt animal growth, improve the feed utilization rate and improve the feed quality.


A new method was presented for the selection of the suitable locations for the generation reserve capacity and its distribution between the different bus-bars of a power system. A new term is proposed for the percentage distribution of the reserve capacity between the generation buses of the system, the expected reserve R. Starting from the predeter¬ mined optimal distribution, the economical total amount of


The active ageing concept includes domain of independent, healthy and secure living which includes financial aspects, measured by risk of poverty and material deprivation. The key questions of this paper are: how are the poverty indicators related to each other in the active ageing index?; in what ways are they related to some of the other indicators included in the index (such as employment)? And which countries in Europe are "winners" and which are "losers" in this particular financial aspects based on the Active Ageing Index? Besides of this, the example of sub-national application of active ageing index for Poland was presented with showing relation of these financial indicators in the analysis.


The invention provides a handrail driving force monitoring device of passenger conveying device capable of reducing the cost of the monitoring system and ensuring the excellent diagnostic accuracy; wherein, the device is equipped with a handrail mean velocity calculating unit (14) which calculates the mean velocity V1 of the handrail (8) by utilizing the output signal 1 of the handrail speed detector (13); a handrail speed amplitude calculating unit (15) which calculates the speed amplitude value delta V of the handrail by utilizing the output signal 1; a motor rotational speed calculating unit (17) which judges the rotational speed driving the motor (1) according to the information driving the torque control device (4); a passenger load ratio calculating unit (21) which calculates the passenger load ratio according to the information driving the torque control device; and a diagnostic unit (19) which diagnosticates whether the handrail driving force is normal according to the mean velocity V1 and the speed amplitude value delta V; wherein, the mean velocity V1 is calculated by utilizing the output signal 1 output lower than the preset passenger load ratio and the output signal 2 of the step speed detector (12).


Perception of Mach bands may be explained by spatial filtering ('lateral inhibition') that can be approximated by 2nd derivative computation, and several alternative models have been proposed. To distinguish between them, we used a novel set of 'generalised Gaussian' images, in which the sharp ramp-plateau junction of the Mach ramp was replaced by smoother transitions. The images ranged from a slightly blurred Mach ramp to a Gaussian edge and beyond, and also included a sine-wave edge. The probability of seeing Mach Bands increased with the (relative) sharpness of the junction, but was largely independent of absolute spatial scale. These data did not fit the predictions of MIRAGE, nor 2nd derivative computation at a single fine scale. In experiment 2, observers used a cursor to mark features on the same set of images. Data on perceived position of Mach bands did not support the local energy model. Perceived width of Mach bands was poorly explained by a single-scale edge detection model, despite its previous success with Mach edges (Wallis & Georgeson, 2009, Vision Research, 49, 1886-1893). A more successful model used separate (odd and even) scale-space filtering for edges and bars, local peak detection to find candidate features, and the MAX operator to compare odd- and even-filter response maps (Georgeson, VSS 2006, Journal of Vision 6(6), 191a). Mach bands are seen when there is a local peak in the even-filter (bar) response map, AND that peak value exceeds corresponding responses in the odd-filter (edge) maps.


To enable quick and comprehensive surveys to be made of dynamic strains in vibrating surfaces, a portable hand-held gauge has been developed. The device consists of a strip of piezoelectric ceramic 0?44 in long, at the ends of which two gramophone sapphire styli are cemented, 0?375 in apart. This element is enclosed in an outer casing with the probes projecting through a diaphragm on the front surface, which is pressed into contact with the vibrating plate. The dynamic strain in the plate can then be measured on a valve voltmeter. Laboratory experiments indicate that the gauge measures correctly, with an accuracy to better than 10%, for frequencies up to 500 Hz, and measurements on the walls of a power transformer indicate that the device measures strain even at the positions of large overall vibration.


The most probable transcription of the graffito written in the system of writing of the SW. (or Tartessian) found in Garvao (Ourique, Beja) is aiot iii. It is a possible personal name related to others which are very well known in the Celtiberian area (Ajo, Aius, etc.). This graffito testifies the maintenance of the indigenous system of writing in the Second Iron Age in the South West of the Iberian Peninsula.


: The aim of this research is to identify the perception of students in Accounting Sciences from Associação Catarinense das Fundações Educacionais (ACAFE) undergraduate courses at the mesoregion of Vale do Itajaí/SC on the process of adaptation to the higher education environment. Therefore, a descriptive research was conducted through a survey with the quantitative approach. Besides, the instrument used was the Academic Experiences Questionnaire that was validated in previous researches. The results demonstrate that female is 68.84% of the respondents; 64.65% chose Accounting Sciences as the first option. Regarding the dimensions indicated in the questionnaires, the Personal is the most difficult one for students in the process of adaptation to higher education, with an average of 3.4; followed by Study (3.5), Interpersonal (3.7), and Career (3.8). The dimension in which students have less difficulty is the Institutional, averaging 4.0. Moreover, it is observed that students who are in the undergraduate course as their first option show more satisfaction and integration than the others. The research concluded that the findings provide to the Accounting Sciences undergraduate course leaders knowledge about the difficulties pointed out by the students in adapting themselves to higher education, which allows the institutions to develop strategies in order to minimize the pointed out difficulties.


A series of 1-aryl-5-amino-4,5-dihydro-v-triazoles bearing at least one hydrogen atom at the C-4 position has been prepared. The NMR features of the above compounds have been studied with the purpose of differentiating the triazolines with a trans configuration from those with a cis configuration. It has been shown that the hydrogen atom at C-4 lying on the same side of the amine group at C-5 always resonates at lower field than the hydrogen atom on the opposite side. This rule can be applied for identifying the configuration of the 5-amino-v-triazolines.


During the summer of 2010, a transcontinental aerial survey mission was performed to acquire 24,000 line km of lidar transects covering >15,000 km 2 representing all ecozones within Canada's boreal forest. The coverage equates to ~21 million 'lidar plots' at the 25 m grid cell resolution. Each 'plot' contains the position and intensity of 1000 to 2000 laser points, which describe the terrain surface and 3D canopy structure, which will be used to predict forest inventory attributes and to support calibration of wide area satellite-based imagery. Furthermore, in similar fashion to geo-located permanent sample plots, the lidar transect flight path from 2010 can be re-surveyed in the future to facilitate monitoring of forest development and change in a consistent and quantifiable manner. The paper describes the mission planning criteria, survey logistical considerations and customised transect data processing routines.


Cytochromes c are electron transfer proteins in which haem is covalently attached to the polypeptide chain via thioether bonds formed from thiol groups of the two cysteines and the two vinyl groups of haem. This attachment is a post translational process and in many species of bacteria as many as approximately twelve gene products, the functions of which are largely unknown, are required. In Gram-negative bacteria the assembly of the c -type cytochromes occurs in the periplasm. Cytochrome c 552 from the thermophilic organism Hydrogenobacter thermophilus is known to be expressed in the cytoplasm of Escherichia coli . This unique example of cytoplasmic assembly of a c -type cytochrome has previously been postulated to result from insertion of haem into the folded apoform of the cytochrome followed by non-catalysed attachment of the haem. This postulate is supported by the present work which has shown that the cytoplasmic assembly of this cytochrome c 552 continues in the absence of the E. coli ccm genes which are needed for 'normal' c -type cytochrome assembly in that organism. Attempts to test the postulate of spontaneous assembly of the cytochrome c 552 with in vitro experiments require large amounts of cytochrome c 552 and its apo protein. A number of procedures for preparing these proteins were investigated. Although a T7-based expression produced lower amounts than was expected, its use led to detection of the apo form of cytochrome c 552 in E. coli . It was shown that this apoform has some secondary structure, whereas mitochondrial apocytochrome c has a random coil conformation. This observation is consistent with, but does not prove, the postulate for cytochrome c 552 assembly. It was unexpectedly found that a strain of E. coli that produces abnormally large amounts of its endogenous c -type cytochromes also made large amounts of cytoplasmic cytochrome c 552 . NMR studies on this material are consistent with a single and 'normal' attachment of the haem to the polypeptide. Thus the unusual cytoplasmic assembly was not different from the usual periplasmic assembly that occurs in the H. thermophilus itself. In E. coli there is a periplasmic cytochrome b 562 that is presumed to acquire its haem in the periplasm. Some of the ccm genes, required for c -type cytochrome assembly, are postulated to code for a system that transports haem to the periplasm. Cytochrome b - 562 synthesis was not blocked by the absence of these genes. This implies that haem provision for cytochrome b 562 synthesis occurs independently of the ccm system. Apocytochrome b 562 could be detected in E. coli with the ratio apo:holo being higher in a strain that produces c -type cytochromes to relatively low levels. It is suggested that the synthesis of both cytochrome b 562 and c -type cytochromes is at least partly a reflection of the rate of production of haem by the cells.


In the article results of researches on remote monitoring of the lands of agricultural purpose in Republic of Kalmykia are resulted and actions to transition to steady land tenure are offered.


Cadmium‐doped InGaAsP/InP double heterostructure lasers (λ∼1.3 μm) have been made for the first time with threshold current densities as low as 1 kA/cm2. The low diffusion rate and distribution coefficient of cadmium facilitate locating the p‐n junction reproducibly at the active region. High yield from a given wafer and a very uniform performance in a wide range of dopant concentrations are observed. The high vapor pressure of the Cd which has deterred previous investigations of this dopant does not seem to be a problem under the conditions used.


A Dissertation submitted to the School of Graduate Studies of the
University of Ottawa in partial fulfillment of the requirements
for the degree of Doctor of Philosophy
Department of Biology
University of Ottawa
Ottawa, Ontario


This paper deals with the policies, strategies, programs and plans of actions in the management of the natural resources in ASEAN. The challenges encountered in the formulation and implementation of the various instruments relating to these, reflect some divergence as well as convergence. The approach to ASEAN's cooperation is the 'ASEAN Way', which may soon be modified by the ASEAN Charter (infra). This paper focuses on ASEAN at the sub-regional level and not at the national level of member states.


A fluidized bed reactor has been employed for the continuous production of solvents from whey permeate using cells of Clostridium acetobutylicum immobilized by adsorption onto bonechar. Substrate diffusion equations have been developed for the bioparticles, and a mathematical model has been advanced to describe the operation of the reactor. The model was fitted to the experimental data using the concept that not all of the biomass within the reactor was active in solvent production. On this basis, less than 5% was 'active' biomass.


We propose a robust method for estimating road curb 3-D parameters (size, location, and orientation) using a calibrated monocular camera equipped with a fisheye lens. Automatic curb detection and localization is particularly important in the context of an advanced driver assistance system, i.e., to prevent possible collision and damage to the vehicle's bumper during perpendicular and diagonal parking maneuvers. Combining 3-D geometric reasoning with advanced vision-based detection methods, our approach is able to estimate the vehicle to curb distance in real time with a mean accuracy of more than 90%, as well as its orientation, height, and depth. Our approach consists of two distinct components—curb detection in each individual video frame and temporal analysis. The first part is comprised of sophisticated curb edges extraction and parameterized 3-D curb template fitting. Using a few assumptions regarding the real-world geometry, we can thus retrieve the curb's height and its relative position with respect to the moving vehicle on which the camera is mounted. Support vector machine classifier fed with histograms of oriented gradients is used for appearance-based filtering out outliers. In the second part, the detected curb regions are tracked in the temporal domain, so as to perform a second pass of false positives rejection. We have validated our approach on a newly collected database of 11 videos under different conditions. We have used point-wise LIDAR measurements and manual exhaustive labels as a ground truth.


To accurately predict disease development can be considered the "holy grail" of risk factor research. It holds the potential to employ preventive treatment thereby nipping RA in the bud. This presentation will review familial risk in RA and the underlying genetic risk factors, as well as environmental risk factors for disease. Autoantibodies are a potent prognostic marker when it comes to the risk of developing RA, and play a key role in current pathophysiological hypotheses. The newest players in the autoantibody field, and latest concepts of how the various risk factors contribute to disease onset will be discussed. Disclosure of Interest None declared


Diabetes Mellitus (DM) is widely recognized as a major cause of blindness, with Diabetic Retinopathy (DR) being the most frequently cited underlying pathophysiologic mechanism. This makes DR, among all ocular manifestations of diabetes, the focus of most diagnostic as well as therapeutic interventions. However, diabetic neurotrophic keratopathy, a common ocular complication of diabetes that is caused by corneal nerve fiber damage, is a diagnostic entity that generated a lot of attention recently in the ophthalmology community for being largely unrecognized, underdiagnosed and generally not treated, rendering a large number of the growing population susceptible to this serious ocular complication. This is largely because of the challenge in diagnosis and management of diabetic neurotrophic keratopathy. In this manuscript, we discuss the epidemiology, pathophysiologic mechanisms, diagnostic challenges and the innovative therapeutic interventions of diabetic neurotrophic keratopathy, an entity with potentially serious implications for diabetic patients, both type 1 as well as type 2 alike.


Autonomous and intelligent vehicles will undoubtedly depend on an accurate ego localization solution. Global navigation satellite systems suffer from multipath propagation rendering this solution insufficient. Herein, we present a real-time system for six-degrees-of-freedom ego localization that uses only a single monocular camera. The camera image is harnessed to yield an ego pose relative to a previously computed visual map. We describe a process to automatically extract the ingredients of this map from stereoscopic image sequences. These include a mapping trajectory relative to the first pose, global scene signatures and local landmark descriptors. The localization algorithm then consists of a topological localization step that completely obviates the need for any global positioning sensors such as GNSS. A metric refinement step that recovers an accurate metric pose is subsequently applied. Metric localization recovers the ego pose in a factor graph optimization process based on local landmarks. We demonstrate centimeter-level accuracy by a set of experiments in an urban environment. To this end, two localization estimates are computed for two independent cameras mounted on the same vehicle. These two independent trajectories are thereafter compared for consistency. Finally, we present qualitative experiments of an augmented reality (AR) system that depends on the aforementioned localization solution. Several screen shots of the AR system are shown confirming centimeter-level accuracy and subdegree angular precision.


Apologies for the simpleness of the patch. I was unsure of how to manipulate the sounds to a higher degree using MaxMSP.


The phenomena of cavitation which occurs when the propeller work can cause adverseeffects. One of them is the ship would miss the thrust so that the speed can not beachieved as expected. Various experiments and researches have been done in an effort toobtain maximum results by reducing or even eliminating cavitation occurring.One of these efforts is to reduce or eliminate cavitation occurring on the hub vortex. Thisis done by modifying the propeller without changing the original design self. Thepropeller boss cap is modified by adding fins / fin, and then examines the differencesbetween the cavitation that occur with a standard cap boss the modified. It is thencalculated how big the impact on the efficiency of the propeller. In this study, propellermodels of type B series 4:45 (model no. 3468) is used. The test conducted in thecavitation tunnel Laboratory for Hydrodynamics, BPP Technology in Surabaya.From the results of efficiency measurements and observations conducted cavitation it wasfound that modifications made to be able to eliminate the hub vortex cavitation therebyincreasing the efficiency up to 8.58%.


Family doctors are seeking more recognition for the special role that they play in the health system of South Africa. They want a greater say in the formulation of public health policies affecting the lives of their patients and their own working environment, but also in the way medical doctors are trained in this country to become generalists. They also want more recognition and support for their efforts to improve their own skills and the standard of care they deliver to their patients.After all, at least 70% of medical doctors in this country are general practitioners. They form the backbone of the medical services in both the urban and rural areas, where they are always in the forefront of the battle against disease and human suffering.


It was observed that for a given steady volume flow rate Q of a shear thinning (1.5 wt.% carboxymethyl-cellulose, CMC) aqueous solution, the tube was buckled from an elliptical shape to a line or area contacted two lobes as the critical external pressure Pe increased. The downstream transmural pressure Ptm was found to be more negative than that at the upstream as the outlet pressure decreased due to stronger tube collapse resulting in reduced cross sectional area. The tube cross sectional area decreased about an order of magnitude from the undeformed one when the compressive Ptm was about 30 mbar at downstream, which was investigated using image analysis near the tube outlet at different Pe. The corresponding maximum flow velocity at the tube center increased about a factor of two as monitored using pulsed Ultrasound Doppler Velocimetry (UVP). A bi-modal velocity profile was observed in the two lobed tube shape from the plane above the horizontal axis of tube center by UVP. The periodic flow characteristics of CMC solution during ramp up and down were found to be different for the same range of Q, due to instantaneous inlet pressure response than that at outlet. The evolution of flow velocity profiles during the periodic ramp flow was measured and the velocity at the tube center increased by an order of magnitude as the time elapsed from 18s to 188s.


The problem of wave radiation and diffraction by submerged spheroids is analyzed using linearized three-dimensional potential-flow theory. The solution is obtained by expanding the velocity potential into a series of Legendre functions in a spheroidal coordinate system. Tabulated and graphical results are provided for added mass and damping coefficients of various spheroids undergoing motions in six degrees of freedom. Graphs are also provided for exciting forces and moments corresponding to a range of incoming wave angles.


INTRODUCTION
Dance therapy is a non-conventional aerobic exercise in cardiovascular rehabilitation. This meta-analysis aimed to update and assess evidence from randomized controlled trials of dance therapy on patients with hypertension.

EVIDENCE ACQUISITION
PubMed, web of science, EBSCO, EMBESE, Cochrane Central Register of Controlled Trials and China National Knowledge Infrastructure databases in English or Chinese were searched and randomized controlled trials were conducted for this meta-analysis to investigate the effects of dance therapy on blood pressure in hypertension patients. Weighted mean difference (WMD) and 95% confidence intervals (CIs) were calculated. Heterogeneity was assessed by I2 test.

EVIDENCE SYNTHESIS
Five studies were included according to the eligibility criteria. Dance therapy could significantly reduce the systolic、diastolic pressure of hypertension individuals (SBP : WMD -11.07mmHg; 95%CI, -14.3 to -8.12mmHg, p<0.00001;DBP:WMD-4.16mmHg;95% CI, -6.44to-1.88mmHg, p=0.0004) when compared with the control group. low heterogeneity was observed in this research (P =0.65; I2=0% to SBP; P =0.57; I2 =0% to DBP). Subgroup analysis results showed that the subgroup of less than 12 weeks intervention group reduce the blood pressure more than those of 12 weeks intervention. Dance therapy reduce the SPB of hypertension individuals in African region better than Europe and America hypertension population.

CONCLUSIONS
Despite the limited number of studies and people involved, the meta-analysis further demonstrated that dance therapy could reduce SBP and DBP in patients with hypertension. The effect of dance therapy intervention on hypertension might be related to duration of intervention and population gene.


In a simple search model of money, we study a special kind of memory that gives rise to an arrangement resembling a payment network. Specifically, we assume that agents can pay a cost to access a central database that tracks payments made and received. Incentives must be provided to agents to access the central database and to produce when they participate in this arrangement. We also study policies that can loosen these incentive constraints. In particular, we show that a "no-surcharge" rule has good incentive properties. Finally, we compare our model with that of Cavalcanti and Wallace.


As the connection for power directional element in main equipment protection is in confusions,the connection and interior angle setting of power directional relay used as back up protections of both line and transformer are analyzed with symmetrical component method and vector diagram.The directional element selects another side voltages.The optimal connection and interior angle setting are given for the power directional elements at high and middle voltage sides.It meets the requirements of power system for protection under both conditions of the another side with and without power supply.A better connection for digital protection is also proposed,which takes the inter phase voltage as the input of the directional element at low voltage side and make interior angle setting easier.


Ragi a versatile staple cereal in Southern Karnataka was used in the prepn. of Idli, a fermented cereal-pulse based product. The quality of the prepd. Idlis was evaluated by physico chem., functional characteristics and acceptability of the prepd. Idlis. The degree of gelatinization was found to be higher in idlis prepd. with whole ragi and black gram dhal. The bulk d. of ragi flour was higher when compared to rice and black gram dhal indicating that the product was easily digestible and absorbable. The water absorption capacity of black gram dahl was higher and hence soft textured idlis were obtained. The texture of idlis analyzed instrumentally indicated that pre soaked whole ragi resulted in softer Idlis. The color of idlis when measured instrumentally showed that idlis prepd. with ragi flour had dark color compared to whole ragi. Incorporation of whole ragi in the prepn. of Idli did not affect the acceptability of the product as sensory scores indicated that all the products were acceptable. Thus it was evident that whole ragi could be used to replace rice in the prepn. of Idli which enhances the nutritional quality without considerable effect on the quality parameters of Idli. [on SciFinder(R)]


We observed the $3snp$ autoionizing Rydberg series of the Be atom in order to investigate the double-photoexcitation processes in two-$s$-electron systems. We employed synchrotron radiation to photoexcite the Be atoms and measured the generated ${\mathrm{Be}}^{+}$ photoions by the time-of-flight method. The $3snp$ $(n=3\text{\char21{}9})$ photoexcitation resonance peaks with interloper state of $3p4s$ that converges to ${\mathrm{Be}}^{+}(3p)$ threshold were observed. We derived the resonance parameters of $3snp$ series from a fitting procedure and obtained the Fano parameter $q$, energy position ${E}_{0}$, and resonance width $\ensuremath{\Gamma}$. These parameters are in good agreement with theoretical values. In the vicinity of the $3s5p$ state these experimental results clearly revealed the influence of the interloper $3p4s$ state, and the comparison with the numerical calculations indicates that more detailed calculations might be required to fully explain this phenomenon.


Ab.'Jtract-The magnet group at LBNL is currently in the process of developing high-field accelerator magnets for use in future colliders. One of the primary challenges is to provide a design which is cost-effective and simple to manufacture, at the same time result ing in good training performance and field quality ad equate for accelerator operation. Recent studies have focused on a racetrack geometry that has the virtues of simplicity and conductor compatibility. The results have been applied to the design of a series of prototype high-field magnets based on Nb3Sn conductor.


The increasing severity of arsenic pollution has progressively threatened human life and attracted much attention. One of the important topics in environmental sciences is to accurately describe the inorganic arsenic transport in heterogeneous porous media, occurring anomalous diffusion phenomenon, which ultimately benefits the control of arsenic pollution. In this paper, we re-evaluate the dataset of the inorganic arsenic transport in porous media in previous work by using a time-Hausdorff fractal model (HADE). Transport experiments of arsenic-carrying (As(V)) ferric humate complex colloids through a quartz sand column were carried out under varying dissolved organic matter (humic acid) concentrations, pH values, ionic strengths, and ferric concentrations. The results show that under our experimental settings, arsenic migration is promoted with the increase of concentrations of HA, ferric ion and sodium ion, and pH to varying degrees. The intensity of arsenic sub-diffusion behavior is opposite to that of arsenic transport. The HADE model can describe the migration behavior of arsenic well, and the value of the time fractal derivative can reflect the diffusion intensity of arsenic migration to a certain extent. By comparing the HADE model, ADE model, and time-fractional model (fADE) to the experimental data, the HADE model can significantly improve all the simulation results of capturing As(V) breakthrough curves (BTCs).


Improving energy efficiency within existing buildings plays a crucial role in achieving the ambitious goal of future CO2 neutrality. For this reason, this contribution outlines the conversion of an existing, decades-old building into a smart office building. Combining this idea with the integration of future technologies – power-to-hydrogen and DC microgrids as well as the integration of existing approved facilities such as a switching matrix system – establishes the concept of a Smart Energy Complex. The setup presented in this contribution allows for both normal operation of the building and power hardware-in-the-loop testing at the same time.


A new type of air-ground communication application framework named FACT (framework for air-ground communication technology with weather-modification aircraft) is presented to track and command weather-modification aircraft to perform ideal cloud seeding. FACT provides a set of solutions from three perspectives, namely, onboard, onground and air-to-ground, with the core purpose of solving the problems of the rapid exchange of information, contract analysis and identifying potential seeding areas when flight plans and meteorological conditions change. On board, the observed data are processed centrally and transmitted downward through air-to-ground communication. The real-time application and sharing of aircraft detection data are strengthened on the ground, and potential areas of operation are automatically identified based on ground data. The communication between the air and the ground achieves a technical breakthrough by realizing double satellite links, adaptive data transmission and VPN channel encryption. Additionally, an application based on FACT is designed and implemented for the real-time command of weather-modified aircraft. This approach has become the key air-to-ground communication system support for more than 40 Chinese aircraft and the big data service support center of airborne data to ensure improved operation of weather-modification aircraft in China.


Anti-collision calculation method is an important technique in the RFID system. On the basis of the research of RFID' s special decoding method and classic anti-collision method in a dynamic environment, using results of the ability of the reader to test the ability of the electronic tags to adjust itself to the blank time frames, controlling the reader's region of communication and allowing the reader to be at its highest efficiency and decoding rate, combined with the binary tree calculation method, the ability of the tags to adjust to the binary tree anti-collision method. When the tags are adjusting to the dynamic environment, at the same time, the tags that are interfering with the process can be removed, improving the stability of the RFID signal. The results shows that as compared to the calculation method used now, this calculation method effectively controls the happening of collisions, increasing the efficiency of the RFID system's reading of tags.


A promotional video clip featuring Ramy Noaman for the Center for News Literacy at Stony Brook University's School of Journalism.


AbstractThe potential global warming impact on the extreme and mean streamflow of the Upper Blue Nile (UBN) River Basin was projected for the 2050s and 2080s by three hydrological models [Nedbor-Af...


The present invention discloses a splicing device and a detecting method detecting lamb, comprising a light-tight housing, a plurality of lasers may emit different wavelengths of laser light laser array consisting of the spectrometer, provided in the upper end of the container within the housing opening, the holder , a circular sample tray disposed within the container, a light emitting head is provided for irradiating light on to the sample holder, provided for receiving the transmitted light on the light receiving plate head container; provided for placement on the sample tray sample of the light-transmitting plate, a light receiving head end height lower than the height of the lower surface of the sample tray; laser array, the light emitting head in turn is electrically connected to the light receiving head and electrically connected to the spectrometer; the present invention has more detection points, the detection data reliability and higher accuracy.


Effects of seven kinds of the Chinese medicinal herb compound additives on growth and blood biochemical indicator of one year old Amur sturgeon(Acipenser schrencki Brandt) were studied.A total of 240 fingerlings were divided into eight groups:seven Chinese medicinal herb compound additives groups and one control group fed by control diets without Chinese medicinal herb additives.The results showed that the Chinese herb compound additives adopted in the experiment have elevated effect on total protein and albumin and globulin level of blood plasma.AKP enzymatic activity in serum increased somewhat except prescription six.That of prescription four and prescription five increased obviously.As to the index reflecting the liver funcition, LHD level in serum of prescription five decreased obviously and ALT level in serum of prescription two obviously decreased too.AST level was cut down obviously in serum of fish of prescription one, prescription four and prescription five group.Level of BUN, SCR, Ca and P were not affected obviously by the Chinese herb compound additives adopted.Level of blood sugar content of prescription two group and prescription four group fish was increased obviously.Serum iron was increased obviously in fish of prescription two, prescription six and prescription seven.It showed that the selected prescriptions have the function to promote organism metabolism.


The Chronobot/Virtual Classroom (CVC) system is a novel time knowledge exchange platform where any pair of users can exchange their time and knowledge. User profile that contains user attributes, preferences, and learning patterns serves as a primary basis to identify exchange partners and determine exchange rates. In this paper, we described the methodology to acquire knowledge about users i.e. user profile from their activities. The association between user profile and user behaviors (e.g. online reading, chatting and time/knowledge exchanging) is identified by several feedback indicators extracted from browsing history, chatting session and exchange transaction. A linear learning model is constructed to fuse multiple feedback indicators to infer user preference. The methods utilizing user profile to identify the exchange partners and determine the exchange rate are also described in detail.


Vegetation has an important influence on slope hydrology and hence slope stability via plant transpiration. Little is known about the relative merit of evergreen versus deciduous shrubs in maintaining suctions through the year. This study aims to quantify the soil-plant-water relations of two shrub species and to identify relevant plant traits that correlate with hydro-mechanical properties of vegetated soil. Corylus avellana L. (Hazel) and Ilex aquifolium L. (Holly) were chosen as contrasting deciduous and evergreen broadleaf species. For each species, three replicates were planted in separated pots of sandy loam soil. Each pot was irrigated until the soil was saturated and then was left to transpire for 20 days. Soil suction, leaf conductance to water vapour (gL ) and soil penetration resistance were recorded. After testing, some key plant traits were determined. It was found that Hazel dried soil faster than Holly. The mean suction induced by Hazel (82.9±1.5 kPa) was 2.7 times greater than that induced by Holly (30.6±8.2 kPa), as Hazel has significantly higher gL and specific leaf area. Both suction and soil penetration resistance were strongly correlated with the total leaf area, but not the total leaf biomass.


Although the entire genome is present within the nucleus of every cell, distinct genes need to be accessed and expressed in different cellular conditions. Accordingly, the nucleus of each cell is a highly organized arrangement of DNA, RNA, and protein that is dynamically assembled and regulated in different cellular states. These dynamic nuclear structures are largely arranged around functionally related roles and often occur across multiple chromosomes. These include large nuclear bodies (i.e., nucleolus, nuclear speckle), smaller nuclear bodies (i.e., Cajal bodies and histone locus bodies), and gene-gene interactions (i.e., transcription compartments and loops). Yet, what molecular components are involved in establishing this dynamic organization have been largely unknown due to a lack of methods to measure the RNA and DNA components of nuclear bodies and their spatial arrangements in the nucleus. Here, we present Split-Pool Recognition of Interactions by Tag Extension (SPRITE), which enables genome-wide detection of higher-order interactions within the nucleus. In the second chapter, we introduce SPRITE and recapitulate known structures identified by proximity ligation and identify additional interactions occurring across larger distances, including two hubs of inter-chromosomal interactions that are arranged around the nucleolus and nuclear speckles. We show that a substantial fraction of the genome exhibits preferential organization relative to these nuclear bodies. Our results generate a global model whereby nuclear bodies act as inter-chromosomal hubs that shape the overall packaging of DNA in the nucleus. In the third chapter, we provide a detailed experimental protocol for performing SPRITE and an automated computational pipeline for analyzing SPRITE data. Finally, in the fourth chapter, we present a dramatically improved implementation of the SPRITE method that enables comprehensive mapping of all classes of RNA in the nucleus, from abundant RNAs encoded from DNA repeats to low abundance RNAs such as nascent pre-mRNAs and lncRNAs. We find that RNAs localize broadly across the nucleus, with individual RNAs localizing within discrete territories ranging from nuclear bodies to individual topologically associated domains. We uncover that nascent mRNAs interact in structures corresponding to nascent mRNA chromosome territories and compartments. Together, these results uncover a central and widespread role for non-coding RNA in demarcating 3D nuclear structures within the nucleus.


Biocide resistance is an increasing concern. However, it is currently unknown if an elevated MIC value for an isolate correlates with a lower log10 reduction in suspension tests or carrier tests. The aim of this review was therefore to evaluate if isolates with a suspected tolerance to a biocidal active substance reveal an elevated MIC value and an impaired efficacy in suspension tests and carrier tests. A Medline search was done on 6 July 2022 using the following terms: "resistance biocidal MIC suspension" (16 hits), "resistance biocidal MIC carrier" (22 hits), "resistance biocidal suspension carrier" (41 hits), "tolerance biocidal MIC suspension" (1 hit), "tolerance biocidal MIC carrier" (4 hits) and "tolerance biocidal suspension carrier" (3 hits). Studies were included when a tolerance or resistance to the biocidal active substance or disinfectant was suspected and at least two of the three endpoints were evaluated in parallel in comparison to the control isolates. In three out of five studies, the elevated MIC values did not correlate with an impaired bactericidal efficacy against the biocide-tolerant isolates. In three out of five studies, an impaired activity in the suspension tests was described that correlated with an impaired efficacy in the carrier tests (peracetic acid-tolerant K. pneumoniae and glutaraldehyde-tolerant M. chelonae; the two other studies did not allow a comparison. Overall, the results from the suspension tests and tests under practical conditions allowed to determine a clinically relevant resistance.


The purpose of this study is to explore the effect of innovation characteristics in adoption of integrated pest management (IPM) practices by paddy farmers in three provinces of Iran. A total of 190 paddy farmers were selected by using proportional stratified sampling. Data
collection was done by a set of questionnaires that was administrated through personal interview. Validity of the questionnaire was confirmed by a panel of experts. To assess the reliability of the questionnaire, Cronbach's alpha was used. The results of structural equation modelling showed that the hypothesized model fit the data. There are positive and direct relationship between compatibility and trial ability of and adoption of IPM practices.


All curriculum materials involving the teaching of language arts at the junior high level in the schools of Newfoundland and Labrador were surveyed. All materials related to metaphor and the instruction of metaphor were studied, and certain conclusions were drawn. -- First, there is a distinct lack of organization of materials related to metaphor. Second, no attempt is made in any of the texts to provide a sequential development of instructional materials. Third, since most material is found in anthologies devoted to a number of topics, the consequence is that treatment of the topic is often superficial and repetitive. -- These conclusions prompted the author to construct two units of lesson plans which were subsequently taught in two separate grade nine academic classes. The majority of the exercises were based upon ideas found in the research literature. Having assessed these lessons the author developed a final unit in metaphor which could be offered to grade nine students.


Having a citizen's opinion is considered the most important method to evaluate a public institution's performance. As a contemporary theory regarding public institutions and private organizations, public value theory provides an alternative approach to evaluating organizations' performance. The current research has provided a new insight to assess the Mobile-government applications (m-gov app) by proposing a new model entitled 'Mobile Government Public Value (MGPV)' to measure the performance of m-gov apps in developing country settings, specifically Jordan. Depending on several theories engaged with information technology, many determinants have been selected to draw the line for evaluating MGPV in Jordan. Measuring the level of m-gov apps' usage was estimated depending on its perceived need, awareness, perceived security, social influence and self-efficacy to gauge the weather of creating or increasing the public value of the m-gov app from a citizen's perspective. In the current research, Structural Equation Model (SEM) was selected to obtain the research objectives. The results have indicated that the m- gov apps perceived need, m- gov apps' awareness, m- gov apps perceived security, and m- gov apps social factors played an essential role in creating public value of m- gov apps through the mediation role of m- gov apps use factor. While m-gov apps' self-efficacy factor did not provide a positive effect on creating the public value of m-government apps.


The invention relates to a gear selection device (1) with a gear selection component (10) for selecting at least one gear (D, P, R). The gear selection component (10) can manually move in a gear positioning plate (11). According to the invention, the gear selection component (10) is rotatably accommodated in the gear positioning plate (11), thereby at least one gear (D, P, R) can be selected in the rotation movement (12) of the gear selection component (10).


Now the access model of the web resource is unsematic and has no pertinence,information redundancy.In order to change these disadvantages,a new catalog notion—semantic catalog which is different from the traditional web structure is put forward.A similar Apriori algorithm is proposed for getting the frequence-sets.Then put the result into the FRSP-tree which includes the ontology.Search in the FRSP-tree and match the pattern of usage to form the semantic-catalogue.


We present evidence that oestrogen receptor activity in human MCF‐7 breast cancer cells is reduced by over‐expression of c‐Jun or c‐Fos proteins and to a lesser extent by Jun B overexpression. In contrast, overexpression of Jun D protein does not affect the activity of the oestrogen receptor. A region of c‐Jun found to be required for repression of oestrogen receptor activity is located outside the DNA binding domain and is not conserved among the three Jun proteins. Finally, we suggest that c‐Jun and c‐Fos act independently to inactivate the oestrogen receptor.


The invention relates to a Geneva motion controller (10) for operating a machine in forward and reversed indexed increments on demand. The controller includes a Geneva wheel (18) which is rotatable with and slidable on the controller output shaft (16), two cam units (20, 22) which are rotatable on axes which are parallel to and located on opposite sides of the output shaft axis, each cam unit including three axially spaced formation arrangements with the central formation of both cam units being adapted to lock the Geneva wheel (18) against rotation while enabling continued rotation of the cam units (20, 22) with the upper formation arrangement of the first of the cam units (22) including a downwardly directed Geneva wheel engaging formation and the lower formation arrangement of the second cam unit (20) an upwardly projecting formation, and a cammed trigger unit for moving the Geneva wheel into contact with any of the three cam unit formation arrangements.


Jaundice is a condition where levels of bilirubin in blood goes above normal levels due to disorders of the liver. This condition is characterized by yellow tinge of skin and the eyes. Since jaundice can be a manifestation of serious hepatic disorders like cirrhosis or hepatitis, it is important that jaundice be taken care of and liver brought to its normal state in a short period of time. Rural people of Bangladesh mostly rely on folk medicinal practitioners for treatment of diseases. We here present two plant-based formulations administered by a practitioner in Jamalpur district of Bangladesh for treatment of jaundice, and discuss the scientific evidence and relevancy of the plants used by the practitioner as hepatoprotective agents and their possible therapeutic efficacy against jaundice.


Environmental damage becomes seriously problem in this decade and the most damager refers to companies. One of their responsibility is publish their Sustainability Report. Sustainability Report helps companies to show their responsibility about the Economy, Social and Environment aspects. Sustainability Report Disclosure follows the guidelines from Global Reporting Initiative (GRI), G3 and G3.1, both consist of three main aspects which are Economic performance, Environment performance and Social performance. In this research, the data  population taken from  companies that publishes Sustainability Report and listed into Indonesia Stock Exchange starts from 2006 – 2013. The result of this research  shows  that  Sustainability  Report  Disclosure  does  not  have  any  significant relation  on  firm  performance  and  firm  value.  Then,  the  disclosure  of  Economy Performance, Environment Performance and Social Performance of Sustainability Report also does not have significant relation on firm performance and firm value


In this work a biomedical wireless radar sensor network (BWRSN), enabling concurrent fall detection and vital signs monitoring, is presented and described. The proposed architecture is intended for indoor applications as a potential ambient assisted living (AAL) technology. Experimental results, conducted in a real room setting with human subjects, demonstrate the need for a wireless sensor network for the targeted application.


In the wake of George Floyd's murder during the summer of 2020, protestors painted large 'BLACK LIVES MATTER' murals on streets of the United States, forcing politicians to confront these words tattooing their cities. Each creation and reception of a Black Lives Matter
 (BLM) mural is entwined within the machinations of city bureaucracies whose foundations are built upon racial capitalism and is enforced by militarized police. To analyse the removal of Black Lives Matter murals is to contextualize them within this history of racialized police violence and
 erasure, but to do so within an environment of mundane policy-hearings. The removal of Tulsa, Oklahoma's BLM mural by its city government will be a case study of how bureaucracy can implement 'race neutral' policy language that 'leaves no choice' but erasure.
 But while some conservative politicians erased BLM murals to neutralize the radical abolitionist and police reform messages, other politicians similarly embraced the creation of BLM murals as a buffer against, instead of a bridge to, making substantial structural change. Washington, DC's
 famous BLM mural will be my exemplar of this type of deceptive radical performative politics. This article explores how protest movements and bureaucracies interact, focusing on how the radical demands of the BLM movement can be subsumed by 'colour blind' city responses and/or
 performative politics while pointing to larger combative histories of how race is policed within the United States.


No part of this publication may be reproduced in any fonn without written pennission from the author and the publisher. Preface The present review-is mainly an attempt at critically reviewing the demersal fisheries of Southeast Asia and the models used for managing them. As most people working in the region will agree, much is wrong with these fisheries: many are overcapitalized; they are always extremely difficult to monitor; and they are beset with problems related to effective enforcement of any selected management scheme. Possibly because of what appear to be intractable practical problems, the theory behind the stock·assess-ment models and the rules of thumb derived therefrom used in the region have been notably neglected, the result being that models which now appear unrealistic have been used for years. The present paper may thus be seen as an attempt to question these rules and models and I hope to set the stage for a fresh look at the problems and their possible solutio~. I realize, however, that this will appear quite presumptuous; after all, haven't our models very well explained the collapse of the sardine, herring and ancho-veta stocks? The first version of the present paper was written while I was a consultant at ICLARM's Manila head· quarters, from 15 June to 20 August 1978. Several iii important papers on the fisheries of the region had not been available to me at that time (especially SCS 1978 a and b, Lawson 1978, and Pope 1979). I have attempted, when preparing the final draft, to incorporate appropriate references to these papers. I have made no attempt, however, to process the raw data given in these papers, which in all cases differ only in details from the data used here. In the case of SCS (1978 a and b), the use of the new set of effort data on the Gulf of Thailand fishery would have forced me to recalculate most of my tables, but would not have changed the conclusions reached here. It is these conclusions which matter most. They differ greatly from those of other authors dealing with this, or similar sets of data. As far as my conclusions are concerned, I suggest, along with Warren S. McCulloch: "Don't bite my fmger-Iook where it is pointing." Pauly, Daniel. 1979. Theory. and management of tropical multispecies stocks: A review, with emphasis on the Southeast Asian demersal fisheries. ICLARM Studies This paper consists …


Design thinking (DT) is gaining ground among academics and practitioners as a means to improve the innovativeness of organizations. However, with few exceptions, DT studies are most entrenched in practice rather than theory- driven research. This weak tie between theory and managerial practice calls for delving into the dynamics of DT for innovation to build stronger foundations for future studies. Therefore, this study provides a theory- based framing of DT for innovation and a critical review of the DT literature to reconcile theory and practice. To this end, we propose framing and advancing DT as a dynamic capability for innovation rooted in lower- level aspects, namely microfoundations. Based on our theoretical framework, we conduct a systematic literature review that unveils the dynamics of DT and the context- specific capabilities to innovate. The contributions of the paper are twofold. First, we provide a theory- based framing of DT and combining it with existing theories in innovation and management (i.e., dynamic capabilities and microfoundations). Second, we review the extant literature on DT for innovation to reconcile previous studies with these theoretical lenses to, hence, guide future research. Based on this interpretation, we then define a number of avenues for future research, thus reconciling practical evidence with theories that can further explain how DT relates to firm innovativeness.


Tuna are mesopredators in oceanic food webs which play an essential role in pelagic communities and high sea ecosystems service. Hence, understanding the environmental preference of commercial tuna species is necessary to project the hot spot and to characterize its habitat. This study used generalized additive models (GAMs) to determine the relationship between the environmental variables derived from satellite data and the abundance of commercial tuna species. We used three environmental data as predictor variables and built seven GAMs models for each tuna species. The result stated that all environmental variables, namely sea surface temperature(SST), sea surface chlorophyll (SSC), and sea surface height (SSH) gave a significant influence on the existence of commercial tuna ($\mathrm{P} < 0.01$) in the study area. Also, we found different spatial patterns among three types of commercial tuna. Bigeye tuna prefers to stay in lower SST, while yellowfin tuna and albacore tuna prefer to stay in a certain SST range. Furthermore, they also have a different pattern of SSH where albacore and bigeye tuna prefer to stay in the higher SSH while yellowfin tuna prefers to stay between 0.49-0.65 m. However, three species have a similar range of SSC.


The potential for chemical H2 storage on liquid organic hydrogen carriers (LOHCs) has focused attention on the catalytic reactions needed to store and release H2 from the LOHCs. Herein we review our recent studies on the use of N-ethylcarbazole and carbazole as LOHCs. Experimental data show that the hydrogenation reactions are relatively facile, although N-ethylcarbazole hydrogenates 10×'s faster than carbazole on a 5 wt% Ru/Al2O3 catalyst at 150°C. Dehydrogenation of dodecahydro-N-ethylcarbazole is more difficult than hydrogenation and is structure sensitive on Pd catalysts. Maximum activity and 100% selectivity to the completely dehydrogenated product, N-ethylcarbazole, was achieved over a 4 wt% Pd/SiO2 catalyst with dPd ∼ 9 nm. The dehydrogenation TOF of dodecahydrocarbazole and dodecahydrofluorene were much lower than dodecahydro-N-ethylcarbazole. DFT was used to identify the dehydrogenation mechanism and explain the experimental observations. Both theoretical and experimental results lead to the conclusion that dodecahydro-N-ethylcarbazole is a better H2storage candidate than dodecahydrocarbazole.


Plasmonic metal nanoparticles have the ability to act as nanoscale antennas for visible and near-IR (infrared) light, leading to increased electromagnetic fields at their surface. As a result, Raman scattering and/or fluorescence from nearby molecules can be enhanced by many orders of magnitude. However, imaging how these molecules interact with the enhanced fields at the surface of noble metal nanoparticles is a challenge due to the diffraction limit of light. In this article, we review super-resolution imaging of plasmonic hot spots using two all-optical readouts, surface-enhanced Raman scattering and surface-enhanced fluorescence, which are used to locate and track single or a few molecules on the surface of nanoscale-roughened metals. These super-resolution imaging techniques allow localization of the emission centroid of an emitter to better than 5 nm and allow mapping of the electromagnetic field enhancement experienced by molecules at the nanoparticle surface.


With the evolution of e-commerce and the popularization of automobiles, a growing number of auto accessories hypostatic stores are searching for a safe, convenient and economical online auto accessories store as a solution. Based on the status quo, some online store' solutions were compared, and a solution that based on Taobao API was proposed which can boost brand promotion, system security and stability on the base of relatively less investment and short development cycle.


The article is devoted to the functioning of Church Slavonic nouns formed by prefix and prefix-suffix methods, based on the materials of various genres and styles of secular written sources, which were included in the canon «Dictionary of the Ukrainian language of the XVI – first half of the XVII century» and its unique Card File.

The main word-forming models of Church Slavonic vocabulary with the prefixes въз- (воз-) / въс- (вос-), въ- (в-, во-), из- / ис-, пред-, пре- (прѣ-), раз- / рас-, съ- (со-), which are borrowed from the Proto-Slavic period through Old Slavic mediation into the Old Ukrainian language, are analyzed.

With these prefixes, more than 120 verb Church Slavonic nouns are attested in the researched sources (25 tokens are formed by the prefix method, the rest are confix derivatives). It was learned that not all formants in the Ukrainian language of XVI – first half of XVII century equally participated in the creation of Church Slavonic nouns.

The most productive word-forming types, from which abstract Church Slavonicisms were formed, were the types with prepositional elements въз- (воз-), из- / ис-, раз- / рас-, съ- (со-) and with another affix -ниє (-ніє, -нїє). A number of derivatives to denote the names of persons are certified with postpositive components –тель and -никъ. Unproductive were the confixes with the suffixes -ость, -ница, -окъ, -ище.

The Church Slavonic words, which are researched, are numerically represented in the works of polemical literature and texts of business and scientific styles. A small number of derivatives are recorded in fiction (including poetry) and chronicle literature of the time under study. It has been observed that some Church Slavonic nouns, formed in a prefix or prefix-suffix way, have expanded their meanings in the Old Ukrainian language. Some of them were core components in various phrases.


We report density functional calculations that clarify atom-scale mechanisms of vapor-phase epitaxial growth of GaN with gas sources of trimethylgallium and ammonia. We identify various stable adsorption structures of a Ga atom and NHx molecules (x = 0–3) on GaN(0001) surfaces and find that NH2 and NH units spontaneously intervene in Ga–Ga surface bonds on Ga-rich GaN(0001) surface. We then explore the reaction in which NH3 on the surface is decomposed and becomes an N-incorporated structure, −Ga–(NH)–Ga–, on the Ga-rich GaN(0001) and find that the reaction occurs with the energy barrier of 0.63 eV. Further exploration reveals that a reaction of H2 desorption occurs with the energy barrier of 2 eV, leaving the N atom incorporated in the Ga–N network. This barrier can be overcome when we consider the chemical potential of an H2 molecule in the gas phase at the growth temperature. This N incorporation on GaN is a new growth mechanism catalyzed by the growing surface.


The terms 'mujtahid' and 'ijtihad' are nowadays among those which have acquired great currency, even sanctity, among the Shi'ah. One would be surprised to know that the term ijtihad was formerly, from the times of the Prophet (S) and for several successive centuries, a Sunni term. It became Shia after undergoing a change of meaning, or what would be more precise to say, the term remained specifically Sunni for several centuries and became 'Muslim', in the wider sense, that is, after undergoing a change of meaning and dissociating itself from its earlier particular sense.


Product of the invention, a squeeze bottle (11) having a) an outlet (12), and b) a plug (13) has a, this plug is a protruding nipple having a neck and a top (31) and includes a top surface (331), an upper communicating a smooth tubular channel (34) (315) and orifice (312) has a, the smooth tubular channel, without removing the cap, blending of semi-solid things are dimensioned such that squeezed through the channel and orifice to the outside of the bottle, the neck of the nipple has a slightly greater protruding height than the thickness of the spoon, nipple neck and flat top of the (323 ) forms a notch (350) that the edge engages the spoon, the orifice when the pressure stops, sufficient to cut flow of the formulation cleanly sharp intersection with the top of the nipple Form part (313), the junction of the top and the nipple neck of the nipple has a slope, c) have a child-resistant cap covering the orifice when not using the formulation (22), the cap sealing the orifice without being abraded nipple.


ABSTRACT A gelator 1 containing naphthalimide and gallic acid derivatives has been designed and synthesised. It forms instant orange-coloured gels from different solvents such as CH3CN-1,4-dioxane (5:1, v/v), toluene-1,4-dioxane (5:1, v/v) and dimethylsulfoxide (DMSO). The morphology of the gels reveals the fibrous network. CH3CN-1,4-dioxane (5:1, v/v) gel exhibits higher mechanical strength than toluene-1,4-dioxane (5:1, v/v) gel as confirmed from lower tan δ value (tan δ = G″av/G′av) in rheological experiment. The CH3CN-1,4-dioxane (5:1, v/v) gel of 1 exhibits sharp response towards aliphatic amines over the aromatic amines causing rapid gel-to-gel transition with colour change. On the other hand, toluene-1,4-dioxane (5:1, v/v) gel of 1 selectively senses fluoride ion (F−) from a series of other basic anions by exhibiting colour change (from orange to blackish brown) of the gel state. By contrast, CH3CN-1,4-dioxane (5:1, v/v) gel underwent gel-to-sol transition in the presence of several anions and did not show any selectivity in sensing. Gelator 1 also shows measurable interaction towards aliphatic amines, F− and AcO− in CH3CN with distinguishable features in electronic spectra and colour change. Compound 1 and F−-coated paper strip which exhibits colour change on heating and cooling has been successfully used as writing kit.


Introduction: In Highland Scotland, patients with Chronic Obstructive Pulmonary Disease (COPD) had prolonged hospital admissions compared to other UK hospitals. Method: The Respiratory team of Raigmore Hospital with patient and community support used the Virginia Mason model of healthcare change with an aim to reduce length of stay (LOS) from 8 days to 5 days without increasing our national low 30 day readmission rate. Results: Nursing in-reach reduced waste and maximised early transfer from our acute admissions unit to our specialist multi-disciplinary team. The estimated date of discharge was set at 5 days. A patient COPD passport was developed and allowed the patient to seek appropriate health-care professional input for their needs which resulted in greater patient satisfaction. A COPD bundle of care and treatment escalation plan ensured a holistic approach to care. Criteria-led discharge empowered senior nursing staff to discharge patients safely and in a timely manner 7 days a week. In the first 12 months, average LOS is 5.2 days and 30 day re-admission rate is 5.59%. This has saved 435 bed days and estimated cost saving of £172 587. Conclusion: A new patient care bundle for patients with COPD has improved patient care and their satisfaction, reduced waste for the Health-Care Professional team and reduced financial expenditure for inpatient admissions in this patient group.


Cloud computing is future generation architecture of IT enterprise. We can move the application software and database to centralized data centers, the maintenance and management is easy and not fully dependable. While working with cloud computing we face new security challenges, which have not well understood. This will study the issue of protecting the integrity of data storage in cloud computing. The introduction of a third party auditor (TPA), user side will helpful to verify the dynamic data stored in the cloud. Using TPA we might face issues like block data modification, insertion and deletion without notice. To overcome these kinds of issues we are proposing the public auditability or data dynamics, this achieves both. Initially we identify the challenges and security issues, and then we show how to construct the verification scheme for the integration of the above mentioned two features. Keywords— Authorize Client Inspection, TPA, Data Dynamics, Cloud Computing, Storage Security, Data Integrity.


The administration of autologous adipose-derived stromal cells (ADSC) and platelet-rich fibrin (PRF) extract by intra-venous injections was investigated as a treatment for canine intervertebral disc disease (IVDD). IVDD is a disease that can cause several symptoms in domestic dogs, ranging from pain to partial or complete paralysis. Five dogs suffered from IVDD that caused hind-legs paralysis with deep pain perception, were treated with autologous adipose-derived stromal cells, vascular fraction, and PRF extract. ADSC were expected to ameliorate symptoms of IVDD due to its antiinflammatory and cell regenerative action. Five sequential intravenous injections applied in one-week interval for five weeks improved condition of treated dogs judged by patients gait score and exercise pattern.


This paper presents directly interpretable atomic resolution images of dislocation structures at interfaces in CdTe/GaAs(001) systems. This is achieved using the technique of Z-contrast imaging in a 300 kV scanning transmission electron microscope in conjunction with maximum entropy image analysis. In addition to being used to further the understanding of the relation between growth conditions and exhibited properties, the data presented provides direct information on the atomic arrangements at dislocation cores.


Most representation schemes that have been efficiently used for syntactic parsing of natural languages can't be used for Macedonian. The main reason is that as a highly inflected language Macedonian offers wide range of sentence constructions with free word order. This paper presents the experience of using AND/OR graphs for representing syntactic knowledge. The system provides visualization of the parsing, as well as a simple morphological analysis.


The spin‐spray plating (SSP) is an equilibrium chemical process with which spinel ferrite films can be grown on a variety of substrate materials at temperatures as low as 100 °C. The process is particularly attractive for the monolithic integration of microwave magnetic and electronic GaAs devices. The study of the electrical characteristics of these films is part of an effort aimed at achieving this integration. Low‐loss microwave magnetic devices require that the materials used have dielectric loss tangents (tan δ) on the order of 0.001 or lower, and dc resistivities greater than 107 Ω cm. In the SSP process, control of the chemical composition of the films is limited by an incompatibility of desirable transition metal ions (e.g., Fe,Ni,Zn,Mn) with the tetrahedral and octahedral cation sites available in the spinel structure. Therefore, the substitution of a specific cation modifies the site distribution of other ions in the spinel lattice. The overall distribution of the metallic cations determines the...


State of the art dimension reduction and classification schemes in multi- and hyper-spectral imaging rely primarily on the information contained in the spectral component. To better capture the joint spatial and spectral data distribution we combine the Wavelet Packet Transform with the linear dimension reduction method of Principal Component Analysis. Each spectral band is decomposed by means of the Wavelet Packet Transform and we consider a joint entropy across all the spectral bands as a tool to exploit the spatial information. Dimension reduction is then applied to the Wavelet Packets coefficients. We present examples of this technique for hyper-spectral satellite imaging. We also investigate the role of various shrinkage techniques to model non-linearity in our approach.


Chilli is an important spice as well as vegetable crop in India. Anthracnose is one of the most devastating diseases wherever chillies are grown under warm and wet season. The disease appears as sunken necrotic lesions with concentric rings of acervuli on fruit. Colletotrichum species responsible for severe outbreaks of anthracnose on chillies in Karnataka state of India are reported. Forty nine isolates recovered from major chilli production areas of Karnataka state were characterized based on morphological and multilocus gene phylogeny using partial ITS , ACT , CHS-1 , GAPDH , CYLH3 , TUB2 , GS and ApMat genes. The results showed the presence of two species, C. truncatum (37 isolates) and C. fructicola (12 isolates). Pathogenecity assays of the two species were confirmed on 'chilli cv Arka Lohith'. Thus, the results of this study can be utilized for devising disease management strategies and for the development of disease resistant varieties for use in commercial production of chilli in India.


Researchers in the field of physical science are continuously searching for universal features in strongly interacting many-body systems. However, these features can often be concealed within highly complex observables, such as entanglement entropy (EE). The non-local nature of these observables makes them challenging to measure experimentally or evaluate numerically. Therefore, it is of utmost importance to develop a reliable and convenient algorithm that can accurately obtain these complex observables. In this paper, with help of quantum Monte Carlo (QMC), we reveal that the statistical variance of EE exponentially explodes with respect to the system size, making the evaluation of EE inaccurate. We further introduce an incremental algorithm based on the framework of QMC to solve this conundrum. The total number of our incremental processes can be quantitatively determined and reasonably adjusted, making it easy to control the precision in practice. We demonstrate the effectiveness and convenience of our incremental algorithm by using it to obtain the highly accurate EE of a 2D Hubbard model as an example. Additionally, our algorithm can be potentially generalized to calculate other numerically statistically unstable observables with exponential variance growth, such as the entanglement spectrum and topological entanglement negativity of correlated boson/spin and fermion systems, as well as other general functions of determinants of Green's functions in interacting fermions. Accurately measuring these complex observables has the potential to inspire the development of physical theories and guide the direction of experiments.


The objective of this study was to assess the possible association between the polymorphism 260C/T of the gene CD14, Arg7S3Gln TLR2, Asp299Gli and Thr39911e TLR4 and -174G/C of the gene IL6 with myocardial infarction in young adults. For that a case control study was conducted and the case group was formed by 102 patients who had myocardial infarction, and the control group by 108 individuais without history of cardiovascular disease. The genotyping was performed by PCR-RFLP. There was no association between the distribution of genotypes of SNPs 260C/T of the gene CD14, Arg7S3Gln TLR2, Asp299Gli and Thr39911e TLR4 and -174G/C of the gene IL6 between the two groups studied (p<O.OS). The serum inflammatory blood profile was related with polymorphism 174G/C IL-6 in the group IAM. The GG genotype was linked with elevated PAI-1 concentrations (p<0.0001), the genotype GC with larger quantities of red blood cells (p=0.02) and CC genotype with high concentrations of fibrinogênio (p<0.01) and leucocytes increased quantity (p<O.OS). The CC genotype of polymorphism of -260C/T CD14 also showed associated with the elevation in PAI-1 concentrations (p<0.0001) and the CT genotype with elevated fibrinogênio concentrations (p<0.01). The GG genotype of the -174G/C IL-6 polymorphism was related with elevated glucose concentrations (p<O.OS) and CC genotype with decrease in the apoA (p <0.01) and HDL (p<0001) concentrations and elevation of the LDL (p <O.OS), total cholesterol (p <O.OS) concentrations. The CT genotype of -260C I T CD14 polymorphism also was Iinked with high total cholesterol concentrations (p <0.0001). In conclusion, the polymorphism is not associated with myocardial infarction in young patients, but the -260CT CD14 and -174 IL-6 SNPs appear to be related to the serum biochemicaJ, hematological and inflammatory blood profile in patients that had myocardial infarction.


Particle accelerators are among the most complex instruments conceived by physicists for the exploration of the fundamental laws of nature. Of relevance for particle physics are the high-energy colliders, such as the CERN Large Hadron Collider (LHC), which hosts particle physics experiments that are probing the Standard Model predictions and looking for signs of physics beyond the standard model.


Social attachment is fundamental for its relevant impact upon survival and reproduction in several animals and particularly so in humans. Recently, much research efforts have been directed towards the understanding of the neurobiological basis of social attachment. Besides oxytocin, vasopressin and specific brain areas, it has also been suggested that neurotrophins (NTs) might be involved. NTs are a family of structurally similar proteins including nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) amongst others, which play an important role in the survival, differentiation and functioning of neurons (Patapoutian & Reichardt, 2001). Preclinical studies suggest that BDNF might be involved in hippocampal degeneration (Duman et al. 1997) following different stressors, such as maternal deprivation (Meaney, 2001). The BDNF changes would render adult animals more vulnerable to exaggerated stress responses and anxious behaviours (Ladd et al. 2004). These findings suggest that BDNF, and perhaps all NTs, might act as mediators to translate the effects of environmental stimuli on the development of the 'social brain'. A type of social attachment that seems to be peculiar to humans is the so-called 'romantic attachment ', which is the establishment of a relationship between two sexual partners (Hazan & Shaver, 1987). Given the lack of information on this topic, we explored the possible relationship between BDNF plasma levels and romantic attachment, as assessed by the Experiences in Close Relationships (ECR) questionnaire (Brennan et al. 1998), a self-report instrument for measuring romantic attachment in adults.