A prototype expert system for the treatment of stochastic control and nonlinear filtering problems is described with several illustrative examples. The system is written in MACSYMA and Lisp. It accepts user input in natural language or symbolic form; it carries out the basic analysis of the user's problem in symbolic form; and it produces FORTRAN code for the numerical reduction of the problem. The system has a module using PROLOG to check the well-posedness of linear and nonlinear partial differential equations specified in symbolic form. Sample sessions with the system are presented to illustrate its operation.


BACKGROUND
Recently, metastasis associated with colon cancer 1 (MACC1) gene was identified by genome-wide search for differentially expressed genes in human colon cancer tissues and metastases. Previously, MACC1 expression was examined in colorectal carcinomas and gastric carcinomas and was found to show significant correlation with peritoneal dissemination.

PATIENTS AND METHODS
In this study, MACC1 expression was analyzed in 60 samples (tumor and the surrounding non-tumorous liver tissue) collected from 30 patients with hepatocellular carcinoma (HCC) using quantitative real-time polymerase chain reaction (QRT-PCR). Results. MACC1 expression score (tumor:normal) in primary HCC was between 0.01 and 4.59 (average±SD=0.68±0.94). Subsequently, clinicopathological data were correlated with the MACC1 expression. It was found that MACC1 expression showed significant correlation with vascular invasion and α-fetoprotein level (p=0.034, p=0.0098, respectively).

CONCLUSION
These results suggest that MACC1 is more frequently expressed in vascular invasive HCC and may serve as a new parameter for the prognostic prediction of HCC.


The B origin of replication of plasmid R6K, one of three active R6K origins of replication, requires most or all of a 1962-base pair (bp) sequence for activity. The nucleotide sequence of a portion of this functional /3 origin was determined in an earlier study (Stalker, D., Kolter, R., and Helinski, D. (1982) J. MOL BioL 161, 33-43). In this work, the sequence of the remaining portion of this 1964-bp segment was obtained. In addi- tion to its activity as an origin of replication, this sequence also contains sufficient information for autonomous replication in Escherichia coli. A 277-bp region containing seven 22-bp direct repeats is present at one end of the B origin segment (Stalker, D., Kolter, R., and Helinski, D. (1979) Proc. NutL A c d Sci. U. S. A. 76, 1160-1154) while the other end contains a 140-bp se- quence that includes a relaxation complex site. The 277-bp direct repeat region is required for activity of the /3 origin. The start of the /3 origin of replication as mapped by electron microscopy (Crosa, J. (1980) J. BioL Chem. 266, 11075-11077) lies approximately 1000 bp away from the 277-bp region. The n structural gene, which makes up most of the sequence between the direct repeats and the /3 origin, is required in cis for /3 origin activity. The n protein also is required for fi origin activity but can be provided in tmns. The nu- cleotide sequence just beyond the s structural gene and within or near the start of fi origin of replication con- tains an open reading frame for a 151-amino acid protein. Deletions from 94 to were obtained within the 1964-bp /3 origin region. In evey case, the deletion results in loss of activity when the plus are in tmns. These observations suggest a requirement for a specific secondary structure over an extensive region for /3 origin activity.


Finite projective geometries, especially the Fano plane, have been observed to arise in the context of certain quantum gate operators. We use Clifford algebras to explain why these geometries, both planar and higher dimensional, appear in the context of multi-qubit composite systems.


This paper presents the short (up to 28 days) and long (up to 180 days) terms strength gain performances of paste backfill samples prepared with two types of Portland composite cement (types PKC/A and PKC/B) and two mill tailings with different sulphur content (tailing samples Tl and T2). For the selection of an optimum paste backfill mixes at 28 days of curing, four binder contents ranging between 4 and 7 wt% were used. The end results showed that paste cylinders with a binder content of 6 and 7 wt% produced maximum unconfined compressive strength values of 0.8 and 0.9 MPa, respectively. Moreover, 7 wt% of binder content was used to evaluate the effects of binder and tailing types on the long term strength performance of cemented paste backfill. As a result, the strength development of paste cylinders with PKC/A binder has shown a 13% higher compressive strength than that of the PKC/B binder. For a given binder type, the hydration process seems to be directly related to the tailings composition and the binder content.


As an emerging economy, Turkey is an interesting case study because it was one of the hardest hit countries by the crisis, with a year-over-year contraction of 15 percent during the first quarter of 2009. At the same time, anticipating the fallout from the crisis, the Central Bank of the Republic of Turkey (CBRT) decreased policy rates by an astounding 1025 basis points over the November 2008 to November 2009 period. In this context, this paper addresses the following broad question: If an inflation targeting framework underpinned by a flexible exchange rate regime was not adopted, how much deeper would the recent recession have been? Taking the most intense year of the crisis as our baseline, namely 2009, counterfactual simulations indicate that rather than the actual contraction of –4.8 percent, the growth outturn would have been –6.2 percent if the CBRT had not implemented countercyclical and discretionary interest rate cuts. Further, if a fixed exchange rate regime was instead in place, then the counterfactual simulations indicate a growth rate of –8.0 percent in 2009. In other words, the interest rate cuts implemented by the CBRT and exchange rate flexibility both helped substantially soften the impact of the global financial crisis. These counterfactual experiments are based on an estimated structural model which along with standard nominal and real rigidities, include a financial accelerator mechanism in an open-economy framework.


We review the possibilities of micro-machined quasi-optical elements for THz radiation and report on the development of such elements at IRAM. Micro-machining of dielectrics permits us to create effective media for the THz frequency range. These media can be used to fabricate novel types of efficient quasi-optical elements. We discuss the technical challenges and compare the results of various modeling approaches with preliminary measurements.


Root locus analysis/synthesis is an extremely powerful tool used in classical control system design. Its results can be used to check stability, speed of response, and system damping. However, the solutions to root locus problems can be extremely difficult to obtain in digital control systems because the poles are in close proximity. Optimized algorithms will be presented which circumvent this problem and allow for fast, accurate z-plane root locus plots. Prompting for data entry, minimum memory in-place computations, and very little processing requirements yield an easy to use, highly efficient program.


An implementation of a frequency domain RAKE receiver for a multi-carrier spread spectrum system is described and its performance is analysed using simulations for a fast fading Doppler channel. This receiver is compared with a conventional time domain RAKE receiver operated over the same channel. The two approaches have similar error rate performances, however, it was found that the multi-carrier system showed performance gains for a four path fading channel. With one and two path channels its performance was limited by the irreducible bit error rate introduced by the fast fading.


A method of cross location in three dimensions is put forward for the shortage of cross location in two dimensions.Direction finding plane of the target in three dimensions is fixed on refract property of radar wave transmitting in the space and azimuth of target to scout stations.The least square method combine with multiple direction finding planes get from the same target can realize cross location and position its site.This method can remove the bias of northern direction.projection map for position precision in the side of two dimension space cross location,and improve the passive direction measurement position accuracy as well.


The transformation of transatlantic security relations after 9/11 remains the subject of extensive scrutiny. Academics and practitioners alike continue to seek an explanation for the stark divergences in national security policies that transpired in the period between 2001 and 2003. This paper argues that the existence of national strategic cultures in shaping states security policies and perspectives towards the use of force in particular is crucial to any comprehensive understanding of recent developments in transatlantic security. Furthermore, only when the perspectives of states from Central and Eastern Europe are brought more centrally into analysis can a clearer prognosis of the longer term consequences for both transatlantic security and Europe's own ambitions to become a secruity actor be reached.


Super materialized labor itself can not create value,but it plays an important role in creating value in process.Playing the role of super materialized labor in the process of value creating to full play,the existing scientific and technological innovation system has to be reformed,and the ratio of transforming the science and technology into productivity has to be improved.It is necessary to increase investment and expand the financing channels of scientific and technological innovation,especially enterprise of technology innovation,and respect labor of science and technology as well as train and introduce more scientific and technical personnel with high quality.


A microwave continuous foaming plate of tire reclaimed rubber is made from material which comprises reclaimed rubber, sulfur powder, zinc oxide, accelerating agent, paraffin, stearic acid, polyethylene glycol-4000, antioxidant, and foaming agent. The preparation method comprises the following steps: a. thinning reclaimed rubber material, then adding the processed rubber and aromatic oil in an open mill to mix; (b) adding paraffin, stearic acid and polyethylene glycol into the rubber in turn at 70-90 degree Celsius, and the processed rubber discharging, calendering at 110-130 degree Celsius, and then cooling, (c)adding sulfur powder, zinc oxide and other additives in the rubber in turn to mix, and then calendering. The processed rubber is foamed and vulcanized in a microwave hot air circulating oven. The plate is cheap, and good in performance. The preparation method which can be done continuously has high yield and low labor intensity.


The religion map of Siberia (1940-1960s) is analyzed. The following problems are considered: population and climatic conditions, migration policy of Soviet government, stages of migration and religion societies in Siberia.


Much has been published about the comparative efficacy of disease modifying antirheumatic drugs (DMARD). However, one must always consider the efficacy of these medications in the context of their toxicity profiles


Neutrosophic sets and soft sets are two different mathematical tools for representing vagueness and uncertainty. We apply these models in combination to study vagueness and uncertainty in K-algebras. We introduce the notion of single-valued neutrosophic soft (SNS) K-algebras and investigate some of their properties. We establish the notion of ( ∈ , ∈ ∨ q ) -single-valued neutrosophic soft K-algebras and describe some of their related properties. We also illustrate the concepts with numerical examples.


The A. describes the life history of Flebotomus longispinus Mangabeira, 1942, the ova, the larvae of the first, second and fourth stages and the female. For lack of material the larval third stage and the puppae were not described.


Aims: The paper empirically investigated the Real Effective Exchange Rate and agricultural productivity in Nigeria. Study Design: Case study. Methodology: The cointegration technique with its implied ECM was applied to estimate the data which covered the period between 1980 and 2011. Results: The result shows that the Real Effective Exchange Rate has significant impact on the level of agricultural output in Nigeria. The result shows that the prices of exports and real agricultural exports have positive and significant impact on agricultural output. The result also showed a satisfactory speed of adjustment. Conclusion: The study shows that the Real Effective Exchange Rate matters for agricultural output in Nigeria. The result thus recommends policy to stabilize the Real Effective Exchange Rate to facilitate improvement in agricultural output.


Abstract A Cd(ΙI)-based luminescent coordination polymer, namely [Cd(L)2(H2O)2]n (1), has been synthesized by 1-(tetrazo-5-yl)-4-(triazo-1-yl)benzene ligand (HL) and structurally characterized. The selective luminescence sensing performances of 1 were systematically studied. Interestingly, it can sensitively detect trace amounts of acetone, Fe3+ and Cr2O7 2- ions through luminescence quenching, respectively. Graphical Abstract


Billions of large orthocone nautiloids occur within an extremely persistent lime packstone bed of the Redwall Limestone through the Grand Canyon region, Arizona and Nevada. The platform facies of the packstone bed is 2 m thick at the top of the Whitmore Wash Member (Osagean Series of Mississippian System). Abundant nautiloids occur within the platform facies of the bed from Marble Canyon, Arizona westward 290 kilometers to Las Vegas, Nevada. The slope facies of the bed, where nautiloids are rare, is 3-to-14-m-thick, light-gray-weathering grainstone occurring northwest of the platform facies in southern Nevada, extreme northwestern Arizona, and southwestern Utah. Both platform and slope facies of the bed are named formally Whitmore Nautiloid Bed (WNB). Bed area exceeds 3 x 10 km and bed volume exceeds 100 km. Orthocone nautiloids assignable to the genus Rayonnoceras show evidence that bodies occupied the shells during mass kill and burial of an entire population. Shell orientation, inverse grading, outsized coral heads, and water-escape pipes indicate rapid deposition of the platform facies from a high-velocity, laminar, low-cohesion, fluidized dispersion of carbonate sand and silt. This moving dispersion can be called a hyperconcentrated flow (volume concentration sediment ≈ 35%, flow density ≈ 1.6 g/cm). Nautiloids and large coral heads were separated within the dispersion being supported as a raft above the highest-density, strongly fluidized, laminar flow. The flow event resembles the process that suspends lithic fragments and pumice clasts within a pyroclastic density current. WNB has internal structure resembling ignimbrite. The hyperconcentrated flow was initiated as a liquefied flow slide, probably in southwest Colorado, and hydroplaned toward southern Nevada at velocity ≈ 5 m/s through the carbonate platform in northern Arizona. When the flow encountered the slope in southern Nevada and southwest Utah, it was transformed into a turbulent, concentrated flow (volume concentration sediment ≈ 25%) depositing most of its sediment mass. Further westward in Nevada the flow lost its hydroplane and became a tractive current. This is the first documentation in the geological literature of a regionally extensive hyperconcentrated sediment gravity flow upon a marine carbonate platform.


A language L over a finite alphabet E is called growth-sensitive if forbidding any set of subwords F yields a sublanguage L F whose exponential growth rate is smaller than that of L. It is shown that every ergodic unambiguous, nonlinear context-free language is growth-sensitive. Ergodic means for a context-free grammar and language that its dependency di-graph is strongly connected. The same result as above holds for the larger class of essentially ergodic context-free languages, and if growth is considered with respect to the ambiguity degrees, then the assumption of unambiguity may be dropped. The methods combine a construction of grammars for 2-block languages with a generating function technique regarding systems of algebraic equations.


Soliton microcombs are self-organized pulses of light sustained in driven Kerr microresonators, intensively studied for applications in integrated photonic technologies and for their rich nonlinear dynamics. In this work, we theoretically study the collective dynamics of the quantum fluctuations of soliton microcombs. We find that the mean field of a dissipative Kerr soliton crystal is accompanied by pulses of squeezed multimode vacuum and derives its operational stability from the strong detuning of the below-threshold parametric process. We present a photonic architecture that enables independent control of the above-and below-threshold states and achieves a high degree of squeezing ( > 15 dB) in the output waveguide with realistic losses. Our work elucidates the quantum dynamics of formation and annihilation in dissipative Kerr soliton systems, and establishes a pathway for the realization of a practical integrated source of multimode squeezedlight.


6501 Legacy Drive, Plano, Texas 75024-3698 (Address of principal executive offices) (Zip Code) (972) 431-1000 (Registrant's telephone number, including area code) Securities registered pursuant to Section 12(b) of the Act: Title of each class Name of each exchange on which registered Common Stock of 50 cents par value New York Stock Exchange Preferred Stock Purchase Rights New York Stock Exchange Securities registered pursuant to Section 12(g) of the Act: None (Title of class) Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. Yes x No o Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or 15(d) of the Act. Yes o No x Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes x No o Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Website, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§ 232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files). Yes x No o Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K (§ 229.405 of this chapter) is not contained herein, and will not be contained, to the best of registrant's knowledge, in definitive proxy or information statements incorporated by reference in Part III of this Form 10-K or any amendment to this Form 10-K. x Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of "large accelerated filer," "accelerated filer" and "smaller reporting company" in Rule 12b-2 of the Exchange Act.


The western coast of Cotentin Peninsula (Normandy, France) is threatened by large marine erosion, about 5 m per year at some places. The Oooding of low -lying areas are also often observed . To prevent these phenomena, the Local authori lies have decided to work out a global coastal protection policy. First at ail, a study is clone of which aims are multiple: to evaluate economic impacts of coastal erosion, to improve the knownledge of sediment transports with field experiments, to define coastal protection in relation to economic analysis and natural environment. Keys-words : coasùine erosion, coastal hazard, field measurements, defense method s, Nonnandy, France


This paper examines a case of using situational teaching approach in Japanese visual-audio-oral course and puts forward the significance,application methods and specific cases of the approach.It expounds the effect of situational teaching approach at the end.That will make Japanese teaching realistic,motivate students' enthusiasm of learning,and broaden their international vision.Turning language teaching into targeted comprehensive ability training will highly improve teaching effects and students' actual application abilities.


The sorting-out work of teaching materials is a basic one in TCM colleges and universities for researching on the modern history and academic history of TCM development. The initial sorting-out work on teaching materials,preserved in the library of Shanghai University of Chinese Medicine,of four TCM schools in Shanghai during the period of the Republic of China was completed. The modern history of TCM development in modern Shanghai was investigated,and the compiling time,writer,course provision,loss and preservation of these materials were found out.


This paper presents a novel method for efficiently solving a trajectory planning problem for swarm robotics in cluttered environments. Recent research has demonstrated high success rates in real-time local trajectory planning for swarm robotics in cluttered environments, but optimizing trajectories for each robot is still computationally expensive, with a computational complexity from [Formula: see text] to [Formula: see text] where [Formula: see text] is the number of parameters in the parameterized trajectory, [Formula: see text] is precision, and [Formula: see text] is the number of iterations with respect to [Formula: see text] and [Formula: see text]. Furthermore, the swarm is difficult to move as a group. To address this issue, we define and then construct the optimal virtual tube, which includes infinite optimal trajectories. Under certain conditions, any optimal trajectory in the optimal virtual tube can be expressed as a convex combination of a finite number of optimal trajectories, with a computational complexity of [Formula: see text]. Afterward, a hierarchical approach including a planning method of the optimal virtual tube with minimizing energy and distributed model predictive control is proposed. In simulations and experiments, the proposed approach is validated and its effectiveness over other methods is demonstrated through comparison.


Some rheological models and their rheological parameters of drilling fluid are introduced in the paper,and Binham Model has been proved unfit most drilling fluids.Power Law Model couldn't reflect the gel strength of drilling fluid,and Casson Model,Herschel-Bulkely Model and Robertson-Stiff Model have wider range of application.Some kinds of mathematical analysis methods to select rheological model of drilling fluid are explained here,among them the regression analysis method and least square method have higher accuracy,and have more extensive application.The problems that exist in the field application of rheological model of drilling fluid are discussed and,development tendency of the field application of rheological model of drilling fluid in prospect is put forward in the end.


Pneumonia is a common lung disease and affects millions of people worldwide each year. The chest X-ray is one of the most commonly accessible radiological examinations for screening and diagnosing lung diseases. Usually, chest X-ray images (CXRs) are taken at physical examination and evaluated by radiologists. The unbalance between tremendous numbers of CXRs and limited number of radiologists need to be solved by Computer Assisted Diagnosis (CAD). As deep neural networks have shown promising results in CAD, we implemented a deep learning-based framework, PNet, for pneumonia detection. 10784 chest X-ray images collected at the Shenzhen No.2 People's Hospital were employed for training and evaluation. The experimental results showed that the proposed PNet (1,695,777 parameters) achieved higher accuracy and F1 score than classical networks like AlexNet (42,725,889 parameters) and VGG16 (27,560,769 parameters).


Technical Universities are formulated to provide wholesome engineering excellence in academics and in related field of education to the students who desire to become engineers. This paper reveals the importance of technical education in southern part of India and the functioning of engineering colleges by providing education, facilities and all other parameters concerned with the development of knowledge, talent and leadership qualities in each individual as an engineering student. Engineering Colleges are one of the most important institutionalized sectors that are in the modern service sectors. Like all over India and the world, southern part of India is also facing stiff competition and is forced to develop new promotional strategies to cater the needs of the customers.


Conventional fluids (ethylene glycol and H2O) heat transfer performance results to be poor when incorporated with an automobile radiator. An experimental study was performed to explore the enactment of automobile radiator using H2O and WO3 nanofluid as operational fluids. Analysis and comparison were carried out for the heat transfer rate and outlet temperature of fluid for various flow rate ranging from 0.2m3/hr to 0.5 m3/hr. Preperation of nanofluid was done for water with 0.0167%, 0.034% and 0.0667% volume concentration of WO3 nanoparticle. The inlet condition of fluid was set at 50°C as the impact for the variation of temperature conditions on system performance were minimal. On experimentation, the maximum increase in the heat transfer rate was by 4.18% on comparison with base fluid.


The article reviews an exhibition by the artist Hans Josephsohn at the Galerie Rechermann in Cologne, Germany from February 9-March 31, 2007.


Potential‐energy surfaces of the lowest singlet and triplet excited states of benzene and pyrazine have been calculated using complete‐active‐space self‐consistent‐field and multireference configuration interaction (MRCI) techniques. We have focused our attention on the saddle points and surface intersections associated with the reaction path to a biradical form called prefulvene. The barrier heights separating the prefulvenic minimum from the minimum of the planar aromatic form on the ππ* excited singlet surface and on the ground‐state surface have been estimated by large‐scale MRCI calculations. The conical intersection of the lowest ππ* excited singlet surface with the S0 surface has been mapped out in two dimensions, the reaction coordinate to prefulvene and the coordinate of maximum coupling perpendicular to it. The relevance of these ab initio potential‐energy data for the interpretation of photophysical relaxation pathways in benzene and pyrazine (''channel‐three'' effect) is discussed.


This blind ore deposit is located in the upper and lower skarnization zone of the core of Jinchanghe Rise.In the verticalness,there is the multiplayer structure of Pb,Zn-Cu-Cu-,Fe-Fe;horizontally,there is the zonation of Fe,Cu-Pb,Zn-Cu.It belongs to the Cu,Fe multimetallic ore deposit of hydrothermal metasomatic skarn type.


Cross-linked polyethylene (XLPE) is an important insulating material in warm dielectric superconducting cable. When it is operated in a high electric field, an electrical tree may occur and cause insulation breakdown. In this paper, the XLPE samples were prepared and a needle-plate electrode was employed. The treeing process at 0, -30, and -60 °C was recorded. The magnetic field applied on the samples was 0, 200, 400, and 600 mT. An electrical tree was initiated by an impulse-superimposed dc voltage. Two types of tree structures were found and their growth processes were recorded. In addition, the fractal dimension and accumulated damage were both calculated and analyzed. The result indicates that there is a magnetic field threshold to accelerate the tree growth, which increases with the decrease in temperature. Above -60 °C, it is below 600 mT and turns out to be higher than 600 mT at -60 °C. The magnetic field influences the tree-growth process by affecting the space-charge distribution.


Wet chemical and Moessbauer spectroscopic investigations of natural Li-Fe micas show relations between the iron distribution, the quadrupole splitting and the Li content. The positive correlation between ferrous quadrupole splitting and Li content found for synthetic Li-Fe micas can be confirmed. A dependence of ferric content on the kind of sample collection is obtained.


Obesity is closely associated with non-alcoholic fatty liver disease which will develop into hepatocellular carcinoma (HCC). Obesity per se is also an independent risk factor for HCC. Lipotoxicity, adipose tissue remodeling, modulation of immune infiltrates in tumors and adipocytes, changes in intestinal microbiome all contribute to the pathogenesis of HCC under obesity condition. These obesity-associated pathogenic factors increase the clinical challenges for the management of obesity-driven HCC. Scutellaria baicalensis Georgi is a perennial herb of the Lamiaceae family. It is clinically used for the treatment of hyperlipemia, atherosclerosis, hypertension and inflammatory diseases. This article reviews the current findings on the molecular basis of the anti-HCC effects of S. baicalensis and its bioactive compounds, and discuss whether the treatments can alleviate or ameliorate the obesity-associated pathogenic factors. This is the first review unravels the therapeutic potential of S. baicalensis and its bioactive compounds for the treatment obesity-driven HCC.


Suitable organic and polymeric based materials for electronic and photonic applications must possess the desired electromagnetic and optical properties to achieve optimal device performance in order to be more competitive with their inorganic counterparts. A new class of biopolymer, processed from purified marine-based deoxyribonucleic acid (DNA), has been investigated for use in both electronic and photonic applications and has demonstrated promise as an excellent dielectric and optical waveguide material. In this paper we present examples of devices using this new DNA-based biopolymer.


Congenital unilateral renal agenesis occurs in 0.93–1.8 per 1000 autopsies, and is usually diagnosed on an incidental imaging examination. Genital anomalies occur in 37–60% of females and 12% of males with congenital unilateral renal agenesis. Abnormalities in females include agenesis, duplication, rudimentary, unicornuate or bicornuate uterus, double or absent vagina, absent or hypoplastic ovary, absent fallopian tube, abnormal external genitalia and others CASE REPORT


COVID-19 pandemic has posed an unprecedented threat to global public health. Health profes sionals caring for COVID-19 patients face insomnia, mental stress, physical exhaustion, stigma, the pain of losing patients and colleagues. Many of them acquired SARS-CoV-2 and some died. Protection of this workforce is of paramount importance to ensure optimal care to patients. Thus, this study contributes to the subject by formulating a deterministic mathematical model SW E IsIaHR (Susceptible - Healthcare workers - Exposed - Symptomatic - Asymptomatic - Hospi talized - Recovered) that combines both healthcare workers (as an independent compartment) and community and focuses on the protection of the healthcare workforce against SARS-COV-2. Benefiting the next generation matrix method, the basic reproduction number (R0) was computed. Routh-Hurwitz criterion and stable Metzler matrix theory revealed that disease-free equilibrium point is locally and globally asymptotically stable whenever R0 < 1, respectively. Lyapunov func tion depicted that the endemic equilibrium point is globally asymptotically stable when R0 > 1. Further, the dynamics behavior of R0 was explored when varying the use personal protective equipment (ξ) and physical distancing (θ). In the absence of protective measures (ξ and θ), the value of R0 was 6.7125 which implies the expansion of the disease. When θ and ξ were introduced in the model, R0 was 0.6713, indicating the decrease of the disease in the community. Numer ical solutions were simulated by using Runge-Kutta fourth-order method. The numerical results illustrated mathematically that protection of health care workers can be achieved through effec tive use of personal protective equipment and minimization of transmission of COVID-19 in the community.


The invention discloses a polylactic acid fiber which has high hydrolysis resistance and friction resistance. The polylactic acid fiber comprises a polylactic acid ingredient, wherein the group at the tail end of a polylactic acid molecular chain is capped, glycidyl ester is used as an epoxy capping agent, and the polylactic acid ingredient is mixed with fatty acid diamide and/or an alkyl substituted type fatty acid monoamide ingredient and a polycarbodiimide ingredient.


The influence of gas throughput as the principal operating parameter, and of downcomer-to-riser cross-sectional area ratio, on local and global heat transfer coefficients in concentric draught tube airlift devices is reported. Heating surface-to-fluid heat transfer coefficients are theoretically and experimentally shown to increase with gas velocity raised to 1/4 power. Depending on the flow conditions, the heat transfer rates were either positively or negatively influenced by the presence of cellulose fibre solids in aqueous suspensions used to simulate mycelial fermentation systems


For companies operating their own fleets, vehicle routing and scheduling software can significantly reduce their operational cost and improve the resource utilisation, whilst at the same time ensuring compliance with loading and driving time regulations. Companies that outsource their transport to a carrier with a dedicated fleet also stand to benefit by staying in control and being able to monitor their carrier's performance.


This paper presents learning control for linear non-minimum phase systems. The desired trajectories are either of finite duration or periodic in time, and the systems undertaken are assumed to perform the tracking tasks repetitively or periodically. Output redefinition is carried out and the zero-dynamics with respect to the redefined output exhibit stable behavior. Both methodologies of iterative learning and repetitive learning are adopted for the controller designs. The stability and asymptotic convergence of the learning systems are established. The effectiveness of the proposed learning control method is demonstrated through numerical simulation results.


In the context of the mandated phaseout of methyl bromide, California's strawberry industry has increased its use of chloropicrin, another soil fumigant that has long been on the market. However, due to its 2010 designation as a toxic air contaminant, the US Environmental Protection Agency and California's Department of Pesticide Regulation have developed enhanced application protocols to mitigate exposures of the chemical to bystanders, nearby residents, and farmworkers. The central feature of these mitigation technologies are enhanced buffer zones between treated fields and nearby buildings. Not only do buffer zones inherently privilege neighbors over farmworkers, but the determinations of the size of these buffer zones are also based on acceptable threshold levels and probabilities that allow significant exposures to those they are designed to protect. Moreover, these protocols require human monitors to detect sensory irritation. While the science and technology studies literature is highly useful for understanding the inextricability of science and politics in developing protective measures and is attentive to what counts as data in setting acceptable thresholds, it tends to overlook that social sorting is intrinsic to such regulation. We thus turn to Foucault's biopolitics to make sense of regulations that are designed to protect but inherently allow some to become ill. Doing so illuminates how determinations of the bright line are at once technical–political as well as implicit decisions about whose bodies count.


We describ e a system LK(c[\lambda]) for refuting CNFformulae, as a restriction of the sequent calculus inwhich every formula in a sequent is defined over atmost \lambda variables. This further generalizes the systemRes(k), a generalization of Resolution to k-DNF introducedin [9]. We adapt the Pudlak-Impagliazzo game([11]) to prove lower bounds for treelike LK(c[\lambda]). Weshow that dynamic satisfiability, which was introducedin [6] to study resolution space complexity, is a sufficient"but not necessary" condition to obtain exponential lower bounds.


The paper chooses the index of urban logistics competitiveness, constructs the evaluation system of urban logistics competitiveness, uses SPSS17.0 to select the four most competitive cities in the 13 major cities of Beijing-Tianjin-Hebei: Beijing, Tianjin, Shijiazhuang, Tangshan, and the four cities are used as the important node cities for the logistics development of Beijing-Tianjin-Hebei. Based on the breaking point theory, using breaking point formula, field strength formula and radiation radius formula, the paper can calculate the location and field strength between the four key nodes cities and the rest of the city, then the paper select the boundary field strength to calculate the logistics impacts of the four cities which are the most competitive in Beijing-Tianjin-Hebei. Finally paper can determine the scope of their impacts. According to the above steps paper can analyze the Beijing-Tianjin-Hebei regional logistics development status, and put forward the relevant countermeasures and suggestions about logistics integration of Beijing-Tianjin-Hebei.


Over a hundred scientists attended the third Swiss COST Chemistry workshop in Basel last October 2002. The scientific programme consisted of some sixty posters illustrating Swiss participation in COST programmes, and ten invited lectures which progressed from small molecule synthesis, via catalysis and diagnostics to chemistry in biological systems.


OBJECTIVE
To evaluate percutaneous epididymal sperm aspiration (PESA) and testicular sperm extraction (TESE) in the diagnosis and treatment of azoospermia.

METHODS
We examined 385 azoospermia patients using the techniques of PESA and TESE.

RESULTS
Of the total number of the azoospermia patients, 64 (16.62%) had sperm in the epididymis and 45 (11.69%) in the testis. Intracytoplasmic sperm injection (ICSI) was applied to 64 of the patients with sperm in the epididymis or testis. The pregnancy rate after the embryo transfer was 39.07%.

CONCLUSION
PESA and TESE, as an effective therapy for azoospermia, can further the classification of azoospermia and provide chances of procreation to azoospermia patients with partial obstruction.


In the UK, there is no specific guidance for the routine testing of medical electrical equipment. Mostly, service organisations perform tests that have become custom and practice over many years, mainly modelled on the tests set out in the IEC60601 series of standards for 'type testing'. The inclusion of these tests in the repertoire of commercial testers has consolidated the position. Although there have been attempts by individuals and interest groups to undertake a risk analysis to establish the value of all this testing and of specific tests, little has been achieved. That may be about to change, since a draft IEC Standard (IEC62353) 1


Blood-glucose monitors, like many biomedical implants, must operate autonomously, integrate into small spaces, and remain inconspicuous to the body. The problem is that, while including a battery large enough to sustain a system through its entire life impedes integration, under-sizing its energy reservoir to fit into a miniaturized platform shortens operational life. Fortunately, harvesting energy saves space because the environment (not the device) stores the energy a system requires. Harvesters, however, generate little power per unit volume so implantable sensors must operate under stringent power constraints. For this reason, this paper presents a 1.3W, 0.6m CMOS current– frequency (I–F) analog–digital converter (ADC). The differential, hysteretic-based ADC proposed uses nA-range input currents to set and compare voltage oscillations against a self-produced reference to resolve the input level an amperometric glucose sensor generates. The prototyped ADC ultimately draws 1.1 A from a 1.2-V supply to resolve 0–32 nA with 4.25 bits of accuracy at a sampling rate of 225 Hz, which relatively simple and well-understood circuit and layout modifications can improve accuracy to over five bits.


Abstract : An ultrasonic viscometer, capable of measuring small liquid volumes such as drops, was developed by utilizing the short effective path length of shear waves in liquids. The viscometer consists of an unplated quartz crystal excited to shear vibrations with the liquid drop to be tested placed on its surface. The vibrations of the natural modes of the quartz plate was represented by a mass-point compliant equation, and the viscosity equation was derived from the knowledge of the energy loss. Suitable electronics was built to drive the crystal and to record the decaying vibrations. A crystal orientation analysis insured a dominant thickness-shear mode not coupled to flexure and face-shear motion. The amount of sound radiated was determined from the change in the quality factor when the crystal was vibrating alone in air and under vacuum.


With Cleansed, Kane dramatizes a microcosm of a society under the power of an unrestrained dictator, a God-like figure named Tinker who maintains control of a former university campus turned into an "institution." Tinker judges and carries out sentences on the inhabitants of his world: Graham, who dies of a heroin overdose in the first scene and remains in the action of the play as a ghostly presence; Grace, Graham's sister, who comes to the institution to retrieve his body; Rod and Carl, a homosexual couple deeply in love; an unnamed female dancer; and Robin, a weak, ineffectual boy. The plot is loosely based on, among other sources, Shakespeare's Twelfth Night, as Grace seeks her (apparently) dead brother, becomes trapped in Tinker's dark world, and eventually decides to become her brother by changing her sex, allowing Tinker to sever her breasts and give her a phalloplasty of Carl's extracted genitalia. Each of the characters is tested by Tinker, who observes them, ascertains their innermost desires and, with strict Orwellian justice, "cleanses" them. According to interviews with the playwright, Kane wrote Cleansed to explore the survival of human love in the midst of violence and devastation.


Objective To approach the clinicopathologic features and prognosis of 35 patients with ovarian clear cell carcinoma,and as well as those with pelvic endometriosis simultaneously.Methods Through slicing successively and examining the paraffin blocks of 35 patients,which have completely clinicopathologic and follow up data,18 cases were from malignant transformation of ovarian endometriosis (EM group),and the other 17 cases without pelvic endometriosis (NEM group).40 cases homeochronous ovarian serous cystadenocarcinoma were randomly selected with control group.To analysis comparatively their common features,clinic symptoms and signs,auxiliary examination,pathological characteristics,treatment and prognosis.Results The median age of EM group is 48 years,which is younger 3 years than NEM group which is 51 years(P0.001),and it is also younger 8 years than control group which is 56 years(P0.001).The mainly symptoms of the patients in EM group are pelvic mass(66.7%),abdominal distention (33.3%) and postmenopausal vaginal bleeding(11.1%);The mainly symptoms of the patients in NEM group are pelvic mass(58.8%),irregular vaginal bleeding before menopause (23.5%) and abdominal distention (17.6%).The duration of pelvic mass is more than half a year in 38.9% of patients in EM group,and there are significant differences compared with NEM group and control group(P0.05).The 5-year survival in EM and NEM group is 72.2% and 47.1%,respectively,both of them are higher than that of control group which is 35.0%.Conclusion In EM group,the years of patients are more younger,and the early-stage cases are common.The 5-year survival of patients in EM group is 72.2% and it is 47.1% in NEM group.There is no differece between them.Although the prognosis in EM group is better than that of NEM group,there is no significant difference between them.It is indicated that their molecular mechanisms are probably different,but their therapies are identical.However.whether they will be changed still require confirmation by further studies.


Micro, Small and Medium Enterprises (MSME) sector has emerged as a highly vibrant and dynamic sector of the Indian economy over the last five decades. The role of the MSME is to encourage entrepreneurship, employment and livelihood opportunities and enhance the competitiveness of MSMEs in the changed economic scenario. Various centrally sponsored industrial and skill development schemes are initiated by MSME and an effort is made to make the industries to reap the benefits of such schemes. The District Industries Centre (DIC) has undertaken various initiatives to motivate local entrepreneurs so that they can take the benefit of the various schemes and generate employment for the local population through Micro, Small and Medium Enterprises. Young budding entrepreneurs are also targeted which can in turn boost the economic development of the country.


The scope of Corporate social responsibility (CSR) has enlarged the role that manufacturing industries could play today for societal development. Manufacturing industries since their inception have made a tremendous impact on a country's economy. Being the second largest contributor in Indian economy, an unsaid obligation lies within them to help the community prosper. The research paper looks into the CSR practices carried out by two large scale manufacturing industries located in the north agrarian belt of India. The challenges in implementation of CSR activities have been understood to provide recommendations for the same. The findings reinforce the fact that manufacturing industries are tremendously contributing towards the community in which they operate and is concluded by recommending on the need to increase the acceptance level by the community in which these industries operate


All receptors that interact with effector systems to modulate the intracellular levels of a second messenger appear to do so via the intermediacy of members of a family of guanine nucleotide binding proteins (Gproteins). Rodbell and coworkers, whilst studying the ability of the peptide hormone glucagon to stimulate adenylate cyclase activity in hepatocytes, were the first to demonstrate definitively a specific requirement for guanine nucleotides in hormonal function (Rodbell et al., 1971a). Since these pioneering studies, it has become increasingly clear that a considerable number of unique but highly homologous G-proteins are the sites of action for guanine nucleotides in these processes. The purpose of this review will be to discuss the techniques that are currently in widespread use to identify and assess the functions of individual members of a subfamily of these signal-transducing G-proteins which are substrates for ADP-ribosylation catalysed by pertussis toxin.


Escherichia coli host has been the workhorse for the production of heterologous
proteins due to simplicity of use, low cost, availability of various expression vectors, and a
plethora of knowledge on its genetic characteristics, but without a suitable signal sequence, this
host cannot be used for the production of secretory proteins. Humulin is a form of insulin used to
treat hyperglycemia caused by types 1 and 2 diabetes. To improve expression and make a straightforward
production of Humulin protein, we chose a series of signal peptides.

The aim of this study was to predict the most excellent signal peptides to express secretory
Humulin in E. coli organism.

Therefore, to forecast the most excellent signal peptides for expression of Humulin in
Escherichia coli, 47 signal sequences from bacteria organisms were elected and the most imperative
elements of them were studied. Hence, signal peptide probability along with physicochemical
features was evaluated by signal 4.1, and Portparam, PROSO II servers respectively. Later, the in-
-silico cloning in a known pET28a plasmid system also estimated the possibility of best signal peptide+
Humulin expression in E. coli.

The outcomes demonstrated that among 47 signal peptides only 2 signal peptides can be
considered as suitable signal peptides.

 Ultimately protein yebF precursor (YEBF_ECOLI) and protein yebF precursor
(YEBF_YERP3) were suggested as the most excellent signal peptides to express Humulin (With D
scores 0.812 and 0.623, respectively). Although verification of these results warrants experimental
analysis.


Abstract : When gas is sheared in torsional flow between two discs, one stationary and the other rotating, and when the distance between both discs is very small so that the velocity gradient is large, then the gas is drawn inside between the discs and a thrust bearing pressure is developed between them. The pressure at the centre of rotation, determined experimentally, was found to be independent of the speed of rotation and of the thrust on the rotating disc; its value was equal to the ambient pressure of the instrument. The values of the rigidity parameters of the gas were calculated. (Author)


Semi-quantitative RT-PCR assay and western blotting were used to detect PRL-3 mRNA and PRL-3 protein expression in forty-five cases of human cervical squamous cell carcinoma specimens and ten cases of normal cervical tissues respectively .There was a significant overexpression of PRL-3 mRNA and protein in cervical squamous cell carcinoma as compared with normal cervical tissues. The differences were significant (P0.01). Furthermore, the expression of PRL-3 in cervical squamous cell carcinoma tissues was correlated to grade of differentiation and lymphatic metastasis (P0.05),but not with age and diameter of tumors (P0.05).PRL-3 may correlate to the occurrence and progress of cervical squamous cell carcinomas. It was related with partial clinical and pathological features of cervical squamous cell carcinomas and may be useful in gene therapy for cervical squamous cell carcinomas.


Abstract To light emitting diodes (LEDs), solving the common non-uniform current injection and efficiency degradation issues in (0001) plane micro-LED is essential. Herein, we investigated the light emission characteristics of various mesa sizes and different p-electrode areas toward the realization of coaxial GaInN/GaN multi-quantum-shell (MQS) nanowires (NWs)-based micro-LEDs. As the mesa area was reduced, the current leakage decreases, and further reduction of the area showed a possibility of realizing micro-LED with less current leakage. The large leakage path is mainly associated with the defective MQS structure on the (0001) plane area of each NW. Therefore, more NWs involved in an LED chip will induce higher reverse leakage. The current density-light output density characteristics showed considerably increased electroluminescence (EL) intensity as the mesa area decreased, owing to the promoted current injection into the efficient NW sidewalls under high current density. The samples with a mesa area of 50 × 50 µm2 showed 1.68 times higher light output density than an area of 100 × 100 µm2 under a current density of 1000 A/cm2. In particular, the emission from (1-101) and (10-10) planes did not exhibit an apparent peak shift caused by the quantum-confined Stark effect. Furthermore, by enlarging the p-electrode area, current can be uniformly injected into the entire chip with a trade-off of effective injection to the sidewall of each NW. High performance of the MQS NW-based micro-LED can be expected because of the mitigated efficiency degradation with a reducing mesa area and an optimal dimension of p-electrode.


We describe the current status of the diffractive vector meson production calculations within the k_t-factorization approach. Since the amplitude of the vector meson production off a proton is expressed via the differential gluon structure function (DGSF), we take a closer look at the latter and present results of our new improved determination of the DGSF from the structure function F_2p. Having determined the differential glue, we proceed to the k_t-factorization results for the production of various vector mesons. We argue that the properties of the vector meson production can reveal the internal spin-angular and radial structure of the vector meson.


Incompleteness limb function makes people not be able to do the activity itself such as communication via telephone. A number of buttons should be suppress when people make a telephone call. This can not be done by some people. An auxiliary apparatus for patients with communication paralysis is one of the solution because with this device the dissable can do a telephone call only with voice commands. It can help patients with paralysis if they left by the person who tends the child . Basically, this is a switch of sound consisting of pre amp, op amp, and sequence the control of the relay. The process of instrument this is with voice commands which remains in a range of frequencies audio and with the amplitude of minimal 6vpp then the voice will turn relay which connected to the his radio mobile. After a switch on, hence mobile would ask for tone or the name of who willin are calling , after mentioned hence automatically mobile will do a call that which those services was readily available on mobile called voice dial , not just do a call this device can also serves to lift incoming calls and can be inferred this device can be used to perform call and lift incoming calls only with voice commands


Core literacy advocates in-depth teaching with high-level thinking. Higher-order thinking is a key ability to adapt to the development of the knowledge age, and cultivating learners' higher-order thinking requires the design of new types of outreach training. Therefore, this article uses the FC knowledge modeling method, in the SPOC environment, through the design of the students to carry out the expansion training of high-level thinking, to promote deep learning, randomly selected two parallel classes in a middle school in Changsha City for teaching practice research, using SPSS24 for significant analysis and evaluation of the effect of the implementation of the expansion design. The conclusions drawn are as follows. Using the strategy of instructional design that focuses on higher-order thinking expansion design can improve the teaching effect. students who use high-order thinking expansion design in the SPOC environment are better than other students in problem-solving ability. This enlightens us to make full use of SPOC curriculum resources and pay attention to students' higher-order thinking training and developmental evaluation.


AutoCAD is a well-established drawing software,and its powerful drawing function is widely fascinated for beginners.However,it is necessary to improve the drawing and designing efficiency when the basic AutoCAD application method is learned.In this paper,some approaches for improving the AutoCAD designing efficiency is proposed,which is concluded based on my own practical implementation and teaching.


Electrocardiogram (ECG) is one of the most important noninvasive tools for the diagnosis of cardiac arrhythmia. Automatic beat classification in ECG is a topic of continuing research. In this paper, automatic classification of 3 beat types - normal sinus rhythm, premature ventricular contraction and left bundle branch block is implemented. QRS detection is done using the Pan Tompkins algorithm. Wavelet decomposition using daubechies 4 wavelet is done. 25 features are extracted for each beat from wavelet analysis, namely - mean, variance, standard deviation, minimum and maximum of detail coefficients and of approximation coefficients. 3 RR interval features are also extracted for each beat. Beat classification is implemented by using OAO (One Against One) SVM (Support Vector Machine). 3 SVM's are designed and final grouping is done by maximum voting. Novel method of feature selection is introduced. Feature selection for a particular SVM is done based on the beats to be classified by that SVM. ECG signals are obtained from the open source MIT-BIH cardiac arrhythmia database. 6355 beats (2036 LBB, 3865 N, 454 PVC) are used for testing the implementation. Accuracy of 98.46%, 98.47% and 99.92% are obtained for left bundle branch block, normal and premature ventricular contraction beats respectively.


Through researching and analysising to the geophysical prospecting software and hardware, has summarized the geophysical prospecting related theory and the development tendency, and explained its application prospect with examples. The geophysical prospecting technology Concluded is the synthesis using for all sorts of corresponding theory, the method and the technology including mathematics, the physics, electronics, the information science, the systems science, the computer technology and so on, to surveys the Earth each physical information, is the main method and the tool of gaining direct information for geophysical prospecting, is the important subject of geoscience studying development.


In this paper the air flow for typical inhalation rates as well as transport and deposition of particles in a realistic human upper airway model were analysed using a validated finite-volume code with user-enhanced programmes. Most important parameters affecting deposition of particles are inlet flow rate, airway geometry and geometric and physical characteristics of particles. The tubular airway model in this study consists of upper trachea-bronchial airways starting from trachea (G0) to second generation of bifurcations (G2) reconstructed from computerised tomography (CT) data of a healthy human. The low Reynolds number (LRN) k-ω turbulence model was used to simulate the laminar to turbulent occurred airflow. The results show that deposition efficiencies (DE) are typically larger during high level breathing (Qin = 60 l/min) than low-level breathing (Qin = 15 l/min) and DE is significantly larger in the right bronchial airway to the left, mainly because of the slightly greater dimensions of the right bron...


The article describes the idea of the facade set, what it is and where applicable. Considered equipment for facade shooting. The ability to implement the data in popular programs.


OBJECTIVE To investigate the effects of tannins from pomegranate bark on endogenous metabolites in rats with renal fibrosis by using metabonomics method,find potential biomarkers and analyze the metabolizing pathway,and provide relevant theoretical background on the treatment of renal fibrosis and utilization of tannins from pomegranate bark.METHODS SD rats were randomly divided into five groups,i.e.,sham operation group,model group,valsartan group,high dose and low dose groups of tannins from pomegranate bark.Except for sham operation group,left ureter of rat was ligated to construct renal fibrosis model,while in sham operated group,ureter would not be ligated or cut off.In the five groups,urine were collected from rats in Week 3 and analyzed by liquid chromatography-high resolution mass spectrometry(LC-MS)to obtain total ion current.Data from LC-MS were pretreated,and imported into SIMCA-P to perform principal component analysis(PCA)and orthogonal signal correction partial least squares analysis(OPLS),and potential biomarkers would be found according to the results of the score and load charts.RESULTS The result of metabolomics analysis showed that the urine of rats was clustering since the third week after model was constructed.Through analysis and identification of important variances,13 potential biomarkers ware screened out.CONCLUSION Distribution of endogenous metabolites of rats with renal fibrosis tends to be the normal level after intervention of tannins from pomegranate bark.It is feasible and effective to find potential biomarkers by metabolomics method.


Abstract Investigations of cobalt dioxygen adducts have lead to a simple, unified description of these complexes. Extension of this description to other metal dioxygen adducts gives insight into the function of biological and catalytic systems. Taking advantage of the high oxidizing power of O2 in a controlled and selective manner is an important goal of chemists. Knowledge of the perturbation made on O2 by coordination to metals is essential to understanding ways to activate it.


Abstract 4-Pyrones bearing electron-donating and electron-withdrawing groups react with nonstabilized azomethine ylides to form pyrano[2,3-c]pyrrolidines in moderate to good yields. The reaction proceeds chemoselectively as a 1,3-dipolar cycloaddition of the azomethine ylide at the carbon–carbon double bond of the pyrone activated by the electron-withdrawing substituent. The reactivity of 4-pyrones toward azomethine ylides was rationalized by computational studies with the use of reactivity indexes. The pyrano[2,3-c]pyrrolidine moiety could be modified, for example by a ring-opening transformation under the action of hydrazine to provide pyrazolyl-substituted pyrrolidines.


This study is entitled Teachers 'Interpersonal Communication Strategies in Instilling Islamic Values in Autistic Children aims to determine how teachers' interpersonal communication strategies in instilling Islamic values in children with autism, what factors affect its success and obstacles.This study uses a qualitative approach with descriptive methods. The paradigm used is constructivism. The theories used are self disclosure by Sidney Marshall Jourard, symbolic interactionism by George Herbert Mead and Blumer, and Gerald Miller's Interpersonal Communication Strategy. students, using media, giving examples of actions, special treatment, habituation, as well as assertiveness. Factors of success that teachers do is by being a creative teacher, the existence of supportive facilities, patience, and cooperation between the school, parents, community. The obstacles are that autistic students have poor communication skills, are easily upset and difficult to communicate, have a mood that is easily changed and difficult to understand their speech, often engrossed in their own world, like to attack, and seek attention. How to deal with it patiently, straighten and direct better, give space to students, adjust conditions, be firm, and dare to stop students.


Titanium dioxide (TiO2) and TiO2-based composite materials have been widely investigated in lithium-ion batteries (LIBs) owing to their small volume change and high safety during the cycling process. However, the low ionic and electrical conductivity of TiO2 nanomaterials leads to poor cycling performances for LIBs. Herein, we successfully synthesized three-dimensional (3D) mesoporous nanocube TiO2/reduced graphene oxide (TiO2/RGO) composites with a simple hydrothermal method without using any surfactants and high-temperature calcination. The as-prepared TiO2/RGO composites are characterized by x-ray diffraction, scanning electron microscopy, electron microscopy, and Brunauer–Emmett–Teller surface area. Benefiting from the RGO conductive substrates and 3D nanotube mesoporous structure, the as-prepared TiO2/RGO composites exhibit high specific capacities of ∼180 mA h g−1 at 1.2 C after 300 cycles as anode materials for lithium-ion batteries (LIBs).


Aim To investigate the effects of fosinopril and valsartan on renal injury in spontaneously hypertensive rats. Methods Twenty 22 week-old male SHRs rats were randomly divided into four groups each consisted of five:hypertensive (SHR)group,Fos group,Val group and Fos+Val group; five 22 week-old male Wistar-Kyoto rats (WKY)as the control group. After 8 weeks,the body weigh,cuff-tail blood pressure,24 hours urinary protein (Upro),left renal weigh/body weigh ratio,urinary N-acetyl-β-D-glucosaminidase (NAGase) and serum creatinine (Scr) were measured; the pathological changes were viewed under light microscopy by HE and Masson. Results The blood pressure of rats in SHR group was significantly higher than those of the other four groups (P0.05),while there was not significantly different in the WKY group,Fos group ,Val group and Fos+Val group(P0.05); the levels of Scr and urinary NAGase were lower,and the contrast of 24h Upro in pre-and post-experiment was significant in Fos grpup,Val group and Fos+Val group as compared to SHR group (allP0.05). In morphology,a typical pathological feature of hypertensive renal injure,and the increased collagen deposited in renal interstitial area,were observed in the renal of SHR group as compared to the control; but the hypertensive renal injury was ameliorated in Fos group,Val group and Fos+Val group. Conclusions Both of fosinopril and valsartan possess effect on the protection of the kidney and retarding renal interstitial fibrosis induced by hypertension,while the effect of combination of fosinopril and valsartan is not more effective than using fosinopril or valsartan alone.


Objective To evaluate the safety and the application values of simultaneous endoscopic treatment for benign prostate hyperplasia and ureteral calculi.Methods Data of 17 patients who underwent simultaneous endoscopic treatment for benign prostate hyperplasia and ureteral calculi in our hospital between August 2005 and June 2010 were retrospectively analyzed.Results All operations were successful with an average operating time of 76.4 min and no transfer to open operation was made.No serve complications occurred except for one case in which the upper ureteral calculi migrated to the kidney pelvis and postoperative ESWL turned out to be successful.No residual calculi were seen two months after operation by B-ultra sonography.No severe complications including urinary incontinence and urinary stenosis were noted 6 months after the operation.Maximum urinary peak flow rate increased postoperatively while international prostate symptom score(IPSS) and quality of life score decreased with significance(P0.05).Conclusion Simultaneous endoscopic treatment for benign prostate hyperplasia and ureteral calculi is both safe and effective.And it is a good choice for treatment of benign prostate hyperplasia and ureteral calculi.


SEROPREVALENCE FOR BOVINE LEUKOSIS VIRUS (BLV) IN DAIRY CATTLE OF CURITIBA AND THE SURROUNDING AREA, PARANÁ, BRAZIL. Enzootic bovine leukosis (EBL) is an infectious and contagious disease caused by bovine leukemia virus (BLV), an oncogenic retrovirus of the family Retroviridae. The present study aimed to evaluate the seroprevalence and respective age influence of BLV in Holstein, Jersey, Brown Swiss and mixed-breed dairy cattle raised in Curitiba and the surrounding area, Paraná, Brazil. A total of 268 samples of bovine serum from five different herds in the counties of São José dos Pinhais, Campina Grande do Sul, Pinhais and Fazenda Rio Grande were tested with immunodiffusion (ID). A total of 151/268 (56.34%) tested seropositive, while 117/268 (43.66%) were considered seronegative. Older animals prsented a significant rise in seropositivity. In conclusion, BLV is widely distributed among dairy cattle of Curitiba and the surrounding area, present in all tested herds, thus requiring adequate application of measures in EBL control and prevention.


: We introduce the notion of oriented projective reconstruction (OPR). We show that, in contrary to common belief, it is possible to obtain more than a projective reconstruction (PR) of a scene from uncalibrated real cameras, namely OPR. This is enabled by knowing that a real camera sees only points in front of it. The de(cid:12)ning property of OPR is that the plane that is in an underlying Euclidean reconstruction at in(cid:12)nity does not intersect the convex hull of the reconstructed points in OPR. This is generally not true for PR. Thus, OPR can be viewed as a step between a(cid:14)ne reconstruction (when the plane at in(cid:12)nity projects to in-(cid:12)nity) and PR (when the position of the plane at in(cid:12)nity is unconstrained). The important practical consequence is that OPR preserves the convex hull, and the reconstructed scene is \topologically correct" and it can be e.g. rendered with hidden surfaces removed correctly.


1. Background Catalysis has gained ongoing attention from academic and industrial community, since it is massively involved in numerous energy and environmental processes, including, among others, the manufacture of value-added fuels and chemicals, hydrocarbons processing, fuel cell applications, photocatalytic degradation, abatement of hazardous substances, etc. To this end, the development of cost-efficient catalysts with improved activity and durability constitutes the main research pillar in the field of catalysis .


A diverse data set of 58 compounds taken from the literature was used to create models for the prediction of the solubility of organic compounds in supercritical carbon dioxide. Descriptors encoding information about the topological, geometric, and electronic properties of each compound in the data set were calculated from the molecular structures. A multiple linear regression model containing seven descriptors was generated. Several new descriptors, which were not present in the original pool, were calculated. One of the new descriptors was used to create the final seven descriptor linear model, which had a better root mean square (rms) error than the original model. The seven descriptors that appeared in the final model were used to make a neural network model which had a significantly better rms error than the linear model.


We investigate the quantum dynamics of many-body systems subject to local, i.e. restricted to a limited space region, time-dependent perturbations. If the perturbation drives the system across a quantum transition, an off-equilibrium behavior is observed, even when the perturbation is very slow. We show that, close to the transition, time-dependent quantities obey scaling laws. In first-order quantum transitions, the scaling behavior is universal, and some scaling functions can be exactly computed. For continuous quantum transitions, the scaling laws are controlled by the standard critical exponents and by the renormalization-group dimension of the perturbation at the transition. Our scaling approach is applied to the quantum Ising ring which presents both first-order and continuous quantum transitions.


Khulna is the third largest city and one of the economic and industrial hubs of Bangladesh. In this respect highway corridor plays a very important part for goods and passenger transport. Due to the ongoing connectivity through construction of Padma Bridge will accelerate the economic activities of this area in near future as well as increase pressure on entry corridor of the city which is directly linked to Khulna-Jessore highway. There are possibilities which can result in low highway performance state. Under the above circumstances, Khulna-Jessore highway was selected as study to evaluate the performance of highway for future perspective. In this regard a field survey was conducted based on various speed study (i.e. spot speed, running and journey speed) analysis. Based on this information various calculation were done such as speed performance index, road congestion index, network assessment index, locational speed fluctuation, speed fluctuation, delay times by moving average method. The speed performance index is 38.59%, road congestion index is 0.36 in peak hour and 0.46 in off peak hour. The lesser the value the more the congestion state of that point. The mean, median and modal speed of the Khulna-Jessore highway is 29.2 km/hr., 27.5 km/hr. and 37.5 km/hr. respectively. The speed falls to 10 to 15 km/hr. due to funneling effect in Khulna-Jessore highway due to uncontrolled on street parking. Moreover, frequent pedestrian crossing and movement of slow moving vehicles also interrupts vehicular speed. Based on these analyses, the results can be significant enough to assess the traffic congestion conditions of urban road networks.


A new represenatation for quantum general relativity is described, which is defined in terms of functionals of sets of loops in three-space. In this representation exact solutions of the quantum constraints may be obtained. This result is related to the simplification of the constraints in Ashtekar's new formalism. We give in closed form the general solution of the diffeomorphisms constraint and a large class of solutions of the full set of constraints. These are classified by the knot and link classes of the spatial three-manifold.


The Muda Irrigation Scheme The M uda Irrigation Scheme was established to fulfill the goals of the National Rice Policy (NRP), i.e., to achieve self-sufficiency in rice production for domestic needs, to improve farmers' socio-economic well-being(visa-vis an increase in farm income) of padi farmers, and to supply rice at a reasonable price to consumers and at a minimal cost to the government. Since 1970 this has been a major component of the New Economic Policy (NEP), through which the government hopes to redress poverty by development of the rice industry. The NEP-NRP-Muda Irrigation Scheme linkage has been evaluated in a corpus of research material. The verdict has not always been positive. As early as 1975, a FAO and World Bank study showed that although real income of the farmers increased by 2.4 times since the introduction of double cropping in the region, this increase was still insufficient to meet the requirement of an average income. This problem was again highlighted in studies conducted by the Center for Policy


Insulator identification in aerial videos is one of the key procedures to the condition analysis for aerial power line inspections. This paper proposes a novel insulator recognition method for images taken by Unmanned Aerial Vehicles (UAVs) with highly cluttered background, which is to adopt a machine learning algorithm Support Vector Machine (SVM) as a classifier to distinguish insulator from the cluttered background based on Gabor features. An innovative background suppression method is proposed to remove the redundant background information as much as possible. The test results show that not only the proposed method can successfully recognize insulator in the aerial images with complex and cluttered background, but also the background suppression procedure can greatly drop the computational load and reduce faulty classification.


A lawsuit scheduled to be heard March 6 in U.S. District Court for the District of Columbia may be the last chance to delay or prevent the Environmental Protection Agency's Internet release of the Sector Facility Indexing Project (SFIP). The controversial information initiative has drawn praise from environmental groups and fierce opposition from state environmental regulators and industry. If it goes on-line on March 7, as EPA plans for it to, SFIP will combine Toxics Release Inventory (TRI) information with chemical hazard, compliance, enforcement, and population data on a facility-specific basis. Although supporters say it's important to provide as much information as possible to the public, opponents say that wrong information and meaningless data will mislead. SFIP has been in the works within EPA's Office of Enforcement & Compliance Assurance for about two years and is part of the agency's reinvention plan. It is a pilot project that, for now, will affect only the petroleum ...


Physics‐informed neural networks (PINNs) are a new tool for solving boundary value problems by defining loss functions of neural networks based on governing equations, boundary conditions, and initial conditions. Recent investigations have shown that when designing loss functions for many engineering problems, using first‐order derivatives and combining equations from both strong and weak forms can lead to much better accuracy, especially when there are heterogeneity and variable jumps in the domain. This new approach is called the mixed formulation for PINNs, which takes ideas from the mixed finite element method. In this method, the PDE is reformulated as a system of equations where the primary unknowns are the fluxes or gradients of the solution, and the secondary unknowns are the solution itself. In this work, we propose applying the mixed formulation to solve multi‐physical problems, specifically a stationary thermo‐mechanically coupled system of equations. Additionally, we discuss both sequential and fully coupled unsupervised training and compare their accuracy and computational cost. To improve the accuracy of the network, we incorporate hard boundary constraints to ensure valid predictions. We then investigate how different optimizers and architectures affect accuracy and efficiency. Finally, we introduce a simple approach for parametric learning that is similar to transfer learning. This approach combines data and physics to address the limitations of PINNs regarding computational cost and improves the network's ability to predict the response of the system for unseen cases. The outcomes of this work will be useful for many other engineering applications where deep learning is employed on multiple coupled systems of equations for fast and reliable computations.


In the present study, the analgesic and anti-inflammatory activities of a new alkaloid (5′-Hydroxymethyl-1′(1,2,3,9-tetrahydro-pyrrolo [2,1-b] quinazolin-1-yl)-heptan-1-one) (compound 1), isolated from Sida cordifolia Linn. was investigated in animal models. The analgesic activity was investigated in the acetic acid induced writhing and the radiant heat tail flick model in mice and the carrageenan induced rat paw edema model was used for anti-inflammatory study. The compound produced significant (p<0.01) analgesic activity in both models. The compound also exhibited significant (p<0.01) inhibition of rat paw edema induced by carrageenan. These results indicated that compound 1 possessed analgesic and antiinflammatory activities.


In the existing scenario most of electricity produced throughout the world is from steam power plants. Coal shares major chunk of fuels used to produce power in thermal power plants in India. Coal reserves are limited and present coal consumption rate is in increasing trend to full fill the power demand. Steam turbine is an excellent prime mover to convert heat energy of steam to mechanical energy. Of all heat engines and prime movers the steam turbine is nearest to the ideal and it is widely used in power plants and in all industries where power is needed for process. About 80% of electricity generation in the world is done by steam turbines. The objective of this work is to evaluate the performance of non-condensing steam turbine by using the energy analysis and energy analysis based on the first law of thermodynamics and second law of thermodynamics respectively. Energy analysis deals with quantity aspect whereas energy analysis deals with quality aspect in addition to quantity. In this analysis, energy efficiency, energy destruction, energy efficiency and turbine heat rate are evaluated based on the requirement of load demand.


A stretchable transmissive hexagonal diffraction grating, which has the potential to act as an optical diffuser, is demonstrated. Leveraging the simplicity of the self‐assembly fabrication process, the photon manipulation capability of polystyrene nanosphere arrays, and elastomeric properties of polydimethylsiloxane, the proposed device is capable of reproducible in situ tuning of both diffraction efficiency and spectral range. While being able to achieve maximum diffraction efficiencies of about 80%, the device displays highly efficient and broadband light diffusion fairly independent of incident light polarization and angle of incidence. Due to its efficient and tunable diffraction capabilities, one potential application of the reported device can be broadband photon management in solar cells and photodetectors by significant increase of the light path length inside the light‐absorbing thin films of these devices. As a proof of concept, the proposed optical diffuser is utilized for light absorption enhancement in colloidal quantum dot semiconductor thin films. The demonstrated devices enable integration of cheap and widely used materials with simple cost‐effective fabrication for photon management in optics, photonics, and optoelectronics.


CP4 3HDM is a unique three-Higgs-doublet model equipped with a higher-order CP-symmetry in the scalar and Yukawa sector. Based on a single assumption (the minimal model with a CP-symmetry of order 4 and no accidental symmetry), it leads to a remarkable correlation between its scalar and Yukawa sectors, which echoes in its phenomenology. A recent scan of the parameter space of CP4 3HDM under the assumption of scalar alignment identified a few dozens of points which passed many flavor constraints. In the present work, however, we show that almost all of these points are now ruled out by the recent LHC searches of t→H+b with subsequent hadronic decays of H+. Apart from a few points with charged Higgses heavier than the top quark, only one point survives all the checks, the model with an exotic, non-2HDM-like generation pattern of H+ couplings with quarks. One can expect many more points with exotic H+ couplings to quarks if the scalar alignment assumption is relaxed.


Thosen (Amer. J. phys. Anthrop., [n.s. 10:155, 1952) listed dominant, irregular donsinant, recessive, and sex-linked genes as the explanation for hypodontia. Grahnhn (Odont. Revy, 7, Sup)pl. 3, 1956) concluded from studies of Swedish families that dominant genes were involved in the majority of cases of hypodontia and that probably a number of genetic entities were associated with its occurrence. Evidence exists for genetic origin in the etiology of hypodontia; however, the mode of transmission is still unsolved. During a survey for chromosome anomalies in oral congenital diseases, a definite abnormality was observed in the karyotype of cells analyzed in an 11-year-old boy with hypodontia. On oral examination, he demonstrated multiple caries in primary and permanent teeth, anterior crowding, and gingivitis. The mandibular right second bicuspid was missing clinically and radiographically. Physical examination revealed a heart murmur and deafness in one ear. His medical history disclosed scarlet fever at age 3 and a tonsillectomy at 8 years of age. His four sisters and one brother were health and had no record of missing teeth. Chromosome preparations, using the method of P. S. Moorhead and others


A 67-year-old woman with drug-resistant paroxysmal atrial fibrillation (AF) without any structural heart disease was referred to our center for catheter ablation. She had no structural heart disease, and left atrial diameter was 45 mm on echocardiography. The procedure was performed under conscious sedation, and the starting rhythm was sinus rhythm. Two decapolar circular mapping catheters (Lasso, Biosense Webster, Diamond Bar, CA, USA) were advanced in the left atrium through a transseptal hole, and were placed in right ipsilateral pulmonary veins (PVs). AF spontaneously initiated


The aim of this study is to identify the creativity elements for technical education and vocational training (TVET) students in Malaysia. The significance of this study is to meet the needs of the industry which require employees to be creative and to help TVET institutions increase the creativity of their graduates. This study utilize Library research approach to gather data from several sources such as journals and electronic media that will explore and identify the elements/construct in student creativity instrument. The study have identified six elements related to the creativity element, namely; intelligence, knowledge, thinking style, personality, motivation and environment.


It is generally assumed that (i) all neurones of the inferior olive send their axons to the cerebellum; (ii) the fibers from the olive end as climbing fibers; (iii) one climbing fiber establishes extensive synaptic contact with one Purkinje cell. From this it has been inferred that there is one inferior olivary neurone per Purkinje cell. The number of neurones in both inferior olives from four cats have been counted in histologic sections. The totals obtained are 145380, 127270, 126920 and 121360, respectively. In two of the cats the Purkinje cells were counted. The ratios of inferior olivary neurones to Purkinje cells were found to be 1 : 10 and 1 : 11, respectively.


SUMMARY

A collection of Chinese ceramics covering the time period 2700-7500 BP has been investigated using adaptations of both the Thellier & Thellier (1959) and Shaw (1974) palaoeintensity techniques. Several rock magnetic techniques were used to investigate the magnetic properties of the samples and on the basis of these measurements some samples were rejected because of their poor magnetic behaviour. Anisotropy of magnetic susceptibility (AMS), thermo-remanent magnetization (TRM) and anhysteretic remanent magnetization (ARM) were investigated. Based on the relationship between ARM and TRM anisotropy, modified ARMs were used for anisotropy correction. Twenty samples were studied using the Shaw method and 34 were studied using the Thellier method. An acceptable agreement between the results from the two methods was found. General features of the secular variation of geomagnetic intensity determined from the present study are consistent with those of the global model of McElhinny & Senanayake (1982).


The mass concentration of catalyst nickel sulfate was decreased by using sodium hypophosphite as reducing agent.Effects of different additives on coating deposition rate,morphology and electrochemical property were investigated.The results show that when the additive is added,the deposition rate remains higher though the mass concentration of nickel sulfate is reduced,the coating morphology improved,and a bright pink copper coating can be obtained.


Data (e.g., event logs) gathered during the execution of business processes enable valuable insights into actual process performance. To leverage this knowledge, these data should be analyzed and interpreted in the context of the respective processes. Corresponding analyses allow for a comprehensive process monitoring as well as the discovery of weaknesses and potential process improvements. This also applies to object-aware processes, where data drives process execution and, thus, is treated as first-class citizen. This paper introduces a dashboard with advanced monitoring functions for object-aware processes.


Objective\ In order to investigate the effect of glial cell line\|derived nerurothophic factor(GDNF)on the neurons of spinal cord and dorsal root ganlia(DRG),we observed the localization of GDNFR\|α on neurons of spinal cord and DRG of rat in vitro. Methods\ The neurons of spinal cord and DRG of rats were cultured.Five days later,these cells were stained with GDNFR\|α polyclone immunohistochemical staining technique. Results\ The positive GDNFR\|α immunoreactivity was present in the neurons of spinal cord and DRG and glial cells. Conclusion\ The present results suggested that GDNF might have some important effects on the neurons of spinal cord and DRG and glial cells in vitro. \;


This book provides an ethnographic contribution to research on children's consumption, family life and happiness. Various and shifting notions of happiness are explored, as well as conditions for a ...


Equipment that is donated to the Foundation needs to be recorded as an in-kind gift. An in-kind gift form needs to be completed and submitted to the University Development and Advancement (UDA) Services Office. You can obtain the in-kind gift form by calling their office at (530) 898-5297. Even though the equipment is acquired differently, all sections of this policy apply to donated equipment as well.


The stereoselective synthesis of the iiii stereoisomer of novel tetraphosphonato-cavitands derived from resorc[4]arene is reported. o -Nitrophenyl- n -octyl ether and n -undecyl- n -decanyl thioether functionalities were introduced in the lower rim of 1 and 2 , respectively, to develop new molecular devices. The crystal structure of the solvated cavitand 1 ·6CH 3 CN was elucidated by X-ray crystallography. C 104 H 104 O 24 N 4 P 4 ·6CH 3 CN crystallizes in the monoclinic space group P 2 1 / c , a =20.574(4), b = 16.591(4), c =33.973(7) Å, g =92.09(2)°, V =11589(4) Å 3 , Z =4, R =0.065. The host molecule has the iiii configuration with the four P&z.dbnd;O bonds oriented towards the molecular cavity. The affinity of molecules 1 and 2 for metal cations was investigated by the liquid-liquid extraction method: among the investigated metal picrates, Ag + , Ba 2+ and Eu 3+ were the best-extracted cations.


proposes that toxic aggregation of Aβ peptides, produced via cleavage of Amyloid Precursor Protein by β-secretase (BACE1) followed by gamma-secretase, leads to neurodegeneration. Inhibition of BACE1 reduces Aβ production, and may slow progression of AD. Verubecestat, a potent BACE1 inhibitor, has been shown to lower CSF Aβ by as much as 80% in healthy controls and patients with AD after one week of once daily dosing. Based on these results, two ongoing phase 3 studies are evaluating the ability of verubecestat to safely delay disease progression in mild to moderate (EPOCH NCT01739348) and prodromal (APECS NCT01953601) AD populations. However, as amyloid deposition takes place years before AD diagnosis, administering an anti-amyloid therapy even earlier in the disease process, before clinical onset, may be necessary to exploit the full potential of this mechanism. Thus secondary prevention trials in individuals with biomarker evidence of Aβ pathology or genetic risk but no clinical symptoms, and primary prevention trials, intervening before the appearance of any pathology, have been proposed as important next steps in testing the amyloid hypothesis. A review of learnings from the ongoing verubecestat and other AD studies in the context of addressing the methodological issues and challenges of earlier intervention studies will be presented.


This study is aimed to provide an approach for measuring the resilience of office buildings against flood in Malaysia. Three states were chosen namely Kelantan, Pahang, and Johor as they had been badly affected by the major flood in 2014. From the three states, nine worst-hit districts had been identified, which are Kota Bharu, Pasir Mas, Kuala Krai in Kelantan, Kuantan, Temerloh, and Pekan in Pahang, along with Batu Pahat, Kota Tinggi, and Mersing in Johor. The Disaster Resilience Scorecard for Industrial and Commercial Building is adapted to construct the scorecard. The essential elements were examined with regards to the office buildings within the scope of flood in Malaysia. This study used Survey questionnaire as a method in constructing the scorecard which was distributed among the managers or person in charge of the office buildings management within the study areas. The results from the survey questionnaire reflected the significance of every component in the essentials, thus relevant to be included in the final scorecard.


The IEEE Solid-State Circuits Society is offering a predoctoral fellowship in solid-state circuits for the academic year 2000–2001. The fellowship includes a stipend of $15,000, tuition and fees up to a maximum of $8,000, and a grant of $2,000 to the department in which the recipient is registered.


A forced by the coronavirus disease pandemic (COVID-19) approach to organization of multidisciplinary conference is described. A hybrid format combining both online and offline presentations is presented and advantages and disadvantages of the used approach are evaluated as well as the received feedback.


Azerbaijan is more associated with oil rather than with gas. However, emerged in the last few years a new trend - the shale gas could be a promising and for the territory of Azerbaijan, which will bring the Azerbaijan Republic to a higher level in the gas production. Unlike conventional gas - shale gas is formed in sedimentary rock composed of clay, low porous deposits, which act both as a source of organic matter, and create favorable conditions for its preservation.Maikop Group is related to one of such complexes which are considered to be an oil source-rock for overlying complexes – Productive Series of Azerbaijan. Rocks of Maikop age can be considered as a prospective for accumulation and formation of shale hydrocarbons fields. Deposits of Chattian regional stage (Upper Oligocene) represent the most prospective stratigraphic part of Maikop Group for formation of deposits of shale hydrocarbons. Middle Kura depression and Northern part of Shamakha-Gobustan of oil-gas-bearing area is the most prospective area for formation of deposits of shale hydrocarbons.


Granule ripples are widespread on Earth and are a fundamental component of dryland sedimentary systems, but the relationship between their wavelength and surface particle size is unclear; in addition, their sedimentary bedding and granule ripple development are incompletely understood. In this study, we examined the relationship between granule ripple development, morphology, and the surface grain‐size distribution. We measured the morphology and particle‐size distribution of granule ripples in China's Kumtagh Desert, and found an exponential relationship between ripple wavelength and average crest particle size, which contradicts previous results. We hypothesize the ripples resulted from creep of coarse particles caused by saltation impacts, accompanied by decreasing bed elevation, leading to crest migration and increased crest height. The size composition and wind regime determined the movement mode of particles, which controlled ripple development and size, but dry–wet and freeze–thaw cycles also contributed. We established a new conceptual model for the development of large granule ripples. Sand ripples and small granule ripples develop similarly, but large ripples did not form from merger of smaller ripples. We report for the first time that particles between 2.3 and 4.7 mm in diameter were missing in the ripple crests (confirmed in wind tunnel experiments). This gap affects the particle movement mode. Since the threshold wind speed for particle saltation at 4.7 mm approaches the regional maximum wind speed, quantifying the missing particles may permit prediction of regional maximum wind speeds, and has practical significance for identifying wind conditions elsewhere, including the surface of Mars.


Objective To compare the cerebral vessels stenosis in acute cerebral infarction patients with or without diabetes mellitus.Methods Using case-control study,51 acute cerebral infarction patients with diabetes mellitus and 64 patients without diabetes mellitus were checked by digital subtraction angiography(DSA).The condition of stenosis and obstruct of vessels in intracranial and extracranial were compared.Results Stenosis of intracranial arteries was frequent in both two groups.The main involved arteries included M1 and M2 segments of middle cerebral artery and external cranial segment of internal carotid artery.The rate of cerebrolvascular abnormality in the patients with diabetes mellitus(84.31%) was higher than that in the patients without diabetes mellitus(70.31%).Stenosis of multiple arteries(52.94%),arteriostenosis combined with ulcer or plaque(39.21%) and collateral circulation development(11.63%) were found in diabetic patients,while the rates were 18.75%,17.19% and 31.11%,repectively,in non-diabetic patients.These differences between two groups were statistical significances(all P0.05).Conclusions More extensive involved arteries,stenosis of more arteries and more stenosis of arteries are found in the cerebral infarction patients with diabetes mellitus compared with the patients without diabetes mellitus.


The level set based curve evolution method is applied to the design process of topology evolution of permanent magnet for cylindrical permanent magnet linear generator (CPMLG). The main contribution is to use the level-set method to reduce the magnetic field distortion of the CPMLG. The corresponding optimization procedure includes: 1) setting the objective air gap magnetic field and selecting proper measure points; 2) performing topology evolution on the permanent magnet based on level-set function; 3) using FEM to analyze the CPMLG with the updated PM by ANSYS Maxwell. Results show that the proposed design method for CPMLG can improve the output performance of the generator.


An advanced combustion mode, Spark Assisted Compression Ignition (SACI) has shown the ability to extend loads relative to Homogenous Charge Compression Ignition (HCCI) combustion but at reduced fuel conversion efficiency. SACI combustion is initiated by a spark, with flame propagation followed by a rapid autoignition of the remaining end-gas fuel fraction. Extending upon previous work [1,2], the Wiebe function coefficients used to fit the two combustion phases are regressed here as functions of the air path variables and actuator settings. The parameterized regression model enables mean-value modeling and model-based combustion phasing control. SACI combustion however, exhibits high cyclic variability with random characteristics. Thus, combustion phasing feedback control needs to account for the cyclic variability to correctly filter the phasing data. This paper documents the success in regressing the cyclic variability (defined as the standard deviation in combustion phasing) at various operating conditions, again as a function of air path variables and actuator settings. The combination of the regressed mean and standard deviation models is a breakthrough in predicting the mean-value engine behavior and the random statistics of the cycle-to-cycle variability.Copyright © 2015 by ASME