Among the most significant developments of American society in the twentieth century is the emergence and rapid growth of the metropolitan area. In i96o, the 212 areas classified as Standard Metropolitan Statistical Areas contained 6~ per cent of the American population compared to about one-third living in the 52 areas which would have been classified as metropolitan areas in i9oo. 1 An intrinsic part of this increased metropolitanisation has been a major shift of population to the suburbs of both the very large and the smaller cities. For example, between 195o and I96o the population living in the central cities of the 212 metropolitan areas increased by only I i per cent compared to a growth rate of 49 per cent for those parts of the metropolitan areas outside the central cities. In fact, as evidenced by the i96o census, many of the central cities actually experienced sharp population losses between i95o and x96o at the very time that metropolitan populations were increasing more rapidly than other segments of the nation. These developments in metropolitan areas involve both a centripetal influx of individuals from outside these areas, a concomitant centrifugal movement of people from the centres to the more distant parts of the metropolitan agglomerations, and differential natural increase. There has been much discussion about the impact and significance of these movements on the demographic and social structure of the population living in various segments of the metropolitan areas. Research to date consists primarily of descriptions of different types of areas which compose a metropolitan agglomeration and of net changes involved in population redistribution within it. ~ Recognising the need for further refinements in the areal units of metropolitan areas, several studies have exploited census data as far as possible to distinguish the growth patterns and the characteristics of different sectors and of types of communities within the zones of the metropolitan area outside the central cities. 3 These studies have documented the fact that in the early phases of metropolitanisation those who moved out of the central cities represented a highly selective segment of the population. As the process continued and the movement to the suburbs accelerated, it also became more diversified in composition. Although the suburban areas have become quite heterogeneous, certain


This study analysed the interconnectedness between economic growth and imports in the short and long run in Zimbabwe from 1975 to 2013. The Zimbabwean economy generally experienced positively associated trend between Gross Domestic Product and imports over the years. For precise and effective policy formulation, it is therefore necessary to understand the nexus between the two mentioned macroeconomic variables. Based on the results of the Johansen causality method, there is a short run unidirectional link between Gross Domestic Product and imports, running from imports to Gross Domestic Product. In the long run no evidence exists for the connection between the two variables according to the Johansen co-integration tests.


Carry out analysis on risk issue about Taobao Newbie's developing logistics financial business using literature method and survey method. It is indicated by research that there're internal operation, policy environment and industry environment risks during Taobao Newbie's developing logistics finance. So countermeasures such as improving business process and monitoring system, supplementing policy defects and establishing risk alarming system etc. have been put forward. Research results have reference significance for e-shopping websites to avoid risks during developing logistics finance business.


Submitted for the MAR11 Meeting of The American Physical Society Giant Spin-Hall Effect and Nonlocal Transport in Graphene DMITRY ABANIN, Princeton, K.S. NOVOSELOV, A.K. GEIM, Manchester, L.S. LEVITOV, MIT — Graphene provides a unique opportunity to explore quantumrelativistic phenomena in a condensed matter laboratory. Interesting phenomena associated with the parity anomaly, including quantum Hall effect in the absence of magnetic field and quantum spin-Hall effect in quantizing magnetic fields, have been theoretically proposed, but could not be observed so far largely due to disorder and density inhonogeneity. We show that weak magnetic field induces large bulk non-quantized spin-Hall effect in graphene. The effect occurs due to Zeeman spin splitting which generates the imbalance of the Hall resistivities of the two spin species. The spin-Hall effect is robust in the presence of disorder and interactions. It will manifest itself in large nonlocal transport mediated by long-lived spin currents, as well as in spin injection and spin accumulation experiments. The effect peaks at the Dirac point, and can serve as a hallmark of the relativistic character of carriers in graphene and other Dirac materials. Dmitry Abanin Princeton Date submitted: 30 Dec 2010 Electronic form version 1.4


Neutron spectra were measured for pure water and for boric acid solutions using the time-of-flight technique. After a critical review of the available calculational methods, three methods were selected for comparison with the experiments. The best method proved to be a transport code (modified DTF-IV) incorporating a bound hydrogen model based on the modified Haywood II frequency spectrum. For the pure-water spectrum, the largest discrepancy between theory and measurement was 16 percent.


The work is part of the UK QIP IRC Grant No. GR/S82176/01. J.W. thanks the Wenner-Gren Foundations for financial support. B.W.L. thanks the Royal Society. J.H.J. acknowledges support from the UK MoD. G.A.D.B. is supported by EPSRC Grant No. GR/S15808/01.


This paper provides a summary of a recent report published by the Federal Highway Administration (FHWA) and conducted at the request of Congress through the 2008 Technical Corrections Act. It summarizes U.S. experience with the temporary use of shoulders as travel lanes as a method to increase the efficient use of highway capacity. Its purpose is to provide a succinct overview of efforts to use left or right shoulder lanes as temporary or interim travel lanes. Implementation issues briefly addressed in the summary include design, traffic control devices, performance measures, potential safety benefits, maintenance concerns, enforcement roles and processes, incident response, training for personnel, costs, liability and legal issues, and public outreach and education. The purpose of this report and its originating study was to shed light on the critical issues that need to be carefully considered should an agency wish to implement temporary shoulder use as well as to highlight issues that need further research in order to provide guidance to agencies on deploying temporary shoulder use deployment without having negative impacts on safety and operations.


In this paper a metallic plate made of steel with an elliptical hole, having fixed long radius and variable short radius is pressure loaded. A comparison is made between the results obtained from analytical equations (from reference 16) for a plate with an elliptical hole and the results obtained from FEA. To show that increasing the order of the element can be one way to improve the results obtained from FEA model two different finite elements (4 node and 8 node plane element) were used on the model. This was shown by measuring the length of the element at the tip of the ellipse. It is possible to produce a more accurate FEA model by increasing the number of elements in a mesh. To show this, the number of elements used to mesh the model were recorded and compared for each ellipse size.


Hedychium spicatum (Zinziberaceae) commonly known as Kapurkachari, is wildely recognized in Ayurvedic system of Indian medicine for antiinflammatory and antistress activities. It is also reported to be tonic and stimulant. The methanol extract of rhizomes of Hedychium spicatum was evaluated for immunomodulatory activity using E. coli induced abdominal sepsis, cyclophosphamide induced myelosuppression, carbon clearance test in mice and forced swim test in rats and anoxia stress tolerance in mice. The extract showed pronounced immunoprophylactic activity in E. coli induced abdominal sepsis by increasing the WBC count and% neutophils. The immunostimulant effect was observed in carbon clearance test by increased Phagocytosis. In cyclophosphamide induced myelosuppression, there was increase in number of WBC in the treatment groups indicating immunostimulant potential of the extract. The extract was found to be effective in forced swim model and anoxia stress tolerance in rats. The extract at dose level 200 and 500 mg/kg was found to be more effective.


A 19 km portion of Highway 2 located between Woodstock and Thamesford was transferred in 1998 from the provincial jurisdiction to the County of Oxford, Ontario. The road was a concrete pavement with 75 mm of hot mix asphalt surfacing. The pavement serviceability was considered poor mainly due to the multiple active joints and rocking of the concrete slabs. In 1999, the County of Oxford made the decision to restore the serviceability of the new County Road 2 using rehabilitation methods that would provide smooth ride, mitigate cracking and eliminate the rocking effect of the concrete slabs. This paper presents an overview of the approach taken by the County of Oxford to establish a pavement rehabilitation strategy and the steps taken to optimize the usage of rubberizing and cold recycling of the old hot mix asphalt surfacing.


Problems in the control of interrelated processes are both important and timely. Devices and systems of "multiple coupling control" are employed in technology (5). As examples of such devices we may mention: the generator of a complex power system in which electrical power plants are connected through a network and load; a jet turbine motor in which the rotation rate and gas temperature are regulated at the turbine exhaust; and aircraft and missiles whose stabilization in space requires regulation of six interdependent variables, etc. Although the theory of control of interrelated processes is still in the initial stages of development (the first research was done in the 1930s), there are already many fundamental works in which the general principles of analysis and synthesis in multiple coupling systems are elaborated.


Much has happened since the 1960s and 1970s, when the idea of self-organization emerged and began to alter our conceptions of human nature, of social organization, and of a social science that had heretofore been wedded to linear causal explanations. The experience that systems could organize themselves has been revo lutionary and constitutes a paradigm shift that is still ongoing. In this article, I distinguish between indigenously and self-organizing systems, consider autopoiesis as a biological step toward selfhood, ascertain the need to distinguish selves and Others, and suggest self-organization as a social phenomenon. I see self-organization as a way of reconceptualizing social organization and human experience. As a result, I close with suggestions to further work on selforganization.


Abstract The nitrogen content of leaves in rice plants at various planting densities in the field and under high and low levels of nitrogen in pots were comparatively examined, and thereby the effect of the nitrogen content of leaves on the nodal positions of the last visible primary tiller on the main stem was clarified. The nodal positions of the last visible primary tiller, which determine the potential number of cumulative tillers, were negatively correlated with the planting density. However, critical nitrogen contents of leaves for tillering on a leaf-area basis (NA), and those on a dry-weight basis (NW) were estimated as 1.4-1.6 g m-2, and 3.8-4.5%, respectively, at the time when the last visible primary tiller emerged, even when the planting densities varied from 24 to197 plants m-2. The critical NA for tillering of rice plants grown under high and low levels of nitrogen fertilization was also nearly the same at the time when the primary tiller ceased to emerge. Therefore, the higher nodal position of the last visible primary tiller caused by lower plant density was attributable to the delayed canopy development and delayed competition for soil nitrogen resources. Suppression of the emergence of the primary tiller when the NA was less than 1.6 g m-2 by an insufficient supply of nitrogen was explained satisfactorily by assuming an insufficient supply of assimilates from leaves to a primary tiller bud.


With the development of automation and control technology, automatic pattern sewing machine has become one of the most important key for major sewing machine manufacturers. To upgrade the competitiveness of the sewing machine goods no more than a simple mechanical structure and reducing the cost of key components, the study of the pattern sewing machine is focus on controlling system architecture, may provide manufacturers that are seeking to develop the same type of electronic controlled sewing machine as a reference.


which it is easier to explain how texts – and inferences from texts, whether biblical, patristic or other – help make and remake communities of behaviour (p. ; on 'worldview' see pp. , ). Slighty clunky as it is, Teubner's binary device thus affords him the clarity and freedom he needs for this essay in the 'kinematics of tradition' (pp. –, acknowledging Alasdair MacIntyre and Jeffrey Stout; also pp. , ). Harnack's Augustine was backward-looking and sin-obsessed. Teubner's, sourced from the texts, is forward-looking and prayerful: 'prayer is the mode through which Augustine envisions the Christian existence as a hope that is caught between desiring the beata vita and waiting patiently for it as a gift' (p. , prefacing a section felicitously entitled 'Failing towards the beata vita'). This is a less ambiguous, more affectively focused description of a state of being that I once incautiously identified with Augustine's 'secular imagination'. It provides the basis for a cogent reading of Boethius' Consolation as an instance of 'Augustinianism ', building (in ch. vi) from other recent research on Boethius' use of Augustine to an analysis of the manifestly Augustinian imaging of the relation between human ratio and divine intellegentia in Consolation . (Less clear, as ever with Boethius, is how any of this might be connected to 'ongoing communal and institutional practice'.) In similar fashion, and with a dexterity not to be conveyed in a short review, chapters on the Regula Benedicti show how the Augustinianism that ultimately counted there is the product not of its author's citations of Augustine 'but rather of his constructive use of Augustine's Christology to inform an understanding of Christian existence' grounded in a life of prayer (p. ). On a hint from Henry Chadwick, Boethius is styled by Teubner a 'Latin Christian'. He and Benedict appear as partners in an 'ongoing reflection on the identity of the Latin theological tradition' (pp. , ). Despite its ecumenism and de-essentialising (p. ), Prayer after Augustine is still written after Harnack. That should not make it a niche work for historical theologians. It also deserves to be read, and to make its mark, alongside interdisciplinary studies such as Markus' End of ancient Christianity (Cambridge ), Brown's Rise of western Christendom (Oxford ) and Ian Wood's Transformation of the Roman West (Leeds ), as a contribution to Kirchengeschichte als Kulturgeschichte.


2014 A new analysis of the fundamental bands of 28SiH4 has been carried out using a Hamiltonian coupled in the Td group. The Hamiltonian matrix was divided into two separate blocks corresponding to the pairs of interacting bands 03BD1/03BD3 and 03BD2/03BD4. In both blocks the Hamiltonian has been developed through the third order for vibrationally diagonal terms as well as for vibrationally off-diagonal terms. Compared to previous studies, the number of parameters used in the calculation of the spectra is strongly decreased and the agreement between experimental and theoretical spectra is improved. Tome 43 No 10 OCTOBRE 1982 J. Physique 43 (1982) 1429-1436 OCTOBRE 1982, Classification Physics Abstracts 33.10 33.20E


Unreasonableness of unconditional increase the enterprise's economic safety is substantiated. General similarity and partial difference between tasks of adaptation recourse control – as a means of increase an enterprise's economic safety – and task of inventory control are demonstrated.


Donor lymphocyte infusion (DLI) is an effective method to establish full donor chimerism or to prevent and treat relapse after allogeneic haematopoietic cell transplantation (allo‐HCT). Usually, DLIs are collected from naïve donors as steady‐state lymphocytes. When donor lymphocytes are collected during stem cell apheresis, donors are pre‐treated with granulocyte colony‐stimulating factor (G‐CSF). However, the impact of G‐CSF stimulation and the resulting composition of DLIs on beneficial anti‐leukaemic responses and survival remain elusive. Therefore, we performed a retrospective analysis to evaluate the role of G‐CSF‐DLIs: 44 patients received either steady‐state DLIs or G‐CSF‐DLIs to prevent and treat relapse or establish full donor chimerism after allo‐HCT. The G‐CSF‐DLI patient cohort showed an improved conversion to full donor chimerism and a lower cumulative incidence of relapse or disease progression without a significantly increased cumulative incidence of graft‐versus‐host disease (GVHD). CD34+ cells, monocytic myeloid‐derived suppressor cells and monocytes as well as donor age and the subsequent occurrence of chronic GVHD were identified as risk factors that significantly improve overall survival after DLI administration. In conclusion, our data suggest that administration of G‐CSF‐DLIs results in graft‐versus‐leukaemia effects without exacerbating GVHD, therefore, improving survival after DLIs.


The complexity and sophistication of computer games is growing every day, not only in terms of graphical resources and advanced interaction mechanisms but also with regards to their narratives and their rules. In this paper we propose to tackle the complexity related to the rules and narratives of a game design by describing it through combinations of more simple game designs. This approach not only facilitates the description of game designs that are easy to manage and understand but also enables the reuse of game design components, and also allows the designer to respond to established trends in computer games such as the use of "missions" and "mini-games". The proposed approach has been applied to the design and implementation of an educational game (EG) called "Safety Village" of the minigame genre, which aims to help raise children's awareness of emergencies and domestic risks.


Energy is a critical factor of economic growth, but the overuse of it results in global warming and climate change. Hence, energy efficiency improvement can help mitigate climate change and prevent economic losses or even ecological extinction. The data envelopment analysis (DEA) approach has been extensively applied for energy efficiency estimation, but past studies of this estimation employ a static mode that does not consider consecutive periods and the carry-over effect. This study estimates energy efficiency under a weight-restricted dynamic DEA (WrD-DEA) model, creates a weight-restricted dynamic energy efficiency (WrD-EE) indicator, and discusses issues concerning the energy decoupling rate and decarbonization. We utilize members in the Group of Seven (G7) and BRICS (Brazil, China, India, Russia, and South Africa) for our experimental observations. The main results herein are: (1) BRICS has larger room for improvement to achieve the standard ratio of the energy decoupling rate than the G7; (2) the G7 and BRICS do not converge to decarbonization; and (3) BRICS exhibits more rapid improvement on energy efficiency than the G7.


The Cote d`Ivoire sedimentary basin is part of a typical transform passive margin developed along the West African coast from Liberia to Ghana. It straddles the coastline and the sedimentary section expands dramatically South of the East-West trending Lagune Fault, with up to 10,000 metres of sediments from Aptian to Present in age. Albo-Aptian rift series, mainly continental clastics without evaporites, have accumulated progressively in a tilted semi-graben. The drift stage marks a widespread marine sedimentation organized in progradational sequences which blanket the Albian block-fault topography of the continental break-up. Reservoirs are mainly clastics and present in the section from Middle Albian to Maastrichtian. Sand bodies are associated with identified submarine fans, infill structures or channelized units deposited in a shelf or outer-shelf environment. Trapping opportunities are due to block-faulting in the rift section, or gravity tectonics in the drift section, often combined with sand pinch-outs to constitute mixed structural-stratigraphic traps. Thick top-seal units formed by marine shales are widespread. Source-rocks have been shown to belong mainly to the rift series and they have been characterized in terms of geochemistry and maturation timing. An efficient simulation model has been used to recontruct the expulsion, migration and trapping of hydrocarbons alongmore » a selected North-South cross-section and to better define the Petroleum Systems.« less


Abstract National seedling has been running for 30 years, but the availability of qualified seed is not enough. This is an opportunity for soybean seed breeding at Subak Kusamba to supply soybean seed, especially for Klungkung regency. The research objective in this study is to determine income generated from soybean seed farming received by farmers and the constraints faced in farming. This study was conducted at Subak Kusamba, Dawan sub district, Klungkung. Samples were selected from all 25 farmers participated in the farming of soybean seed. Methodology in this study includes descriptive qualitative, farming analysis and Revenue/Cost (R/C) ratio. Results showed that the income received by farmers was Rp 2,191,885.84 for an average of 34,08 are of land for one growing season. The R/C ratio was 3.07, implying that soybean seed farming is beneficial. Constraints faced by farmers were decreased rainfall in 2014 which affected the activity and productivity of soybean. Due to the lack of water availability, it is suggested to develop water reservation, especially during dry season by developing water tanks or other irrigation systems technology. To reduce variable costs, it can be done through the use of organic fertilizer or compost, superior seeds and soybean harvesting machines. Keyword: seed breeding, soybean, farm analysis


Karstification recently discovered in the Three Gorges Reservoir region is a vital engineering geological problem.The reliable karst evidence was discovered early in Cuiping area,Wushan County,and the authors' investigation has revealed that the limestone of Triassic Jialingjiang Formation(T1j)in the area generally has suffered strong karstification.There are different features and intensities of karstification in different parts.Longitudinally,there exists intensifying tendency of karstification from the hill top to bottom,and from surface to the depth,there exists local strong karst layer.Many slope-parallel or layer-parallel caves near the surface and beehive-like dissolved holes in depth were generated by karstification in the area.Some karst landforms like neck-shaped karst trough,uvala between two gullies and dissolution tableland,and some structures in connection with the landform such as flying-goose-shaping folds,normal karst faults and brush-shaped close-spaced joint zones were also produced by karstification.The karstification accompanied other exogenous processes,and many types of secondary rockmasses and soils were generated together with the processes.Due to karstification,the quality of rockmass will drop gradually and,what is more,there might occur geo-hazards such as uneven subsidence,fissure,landslide,collapse,mud flow and cave-in.


The second (unphysical) critical charge in the 3-body quantum Coulomb system $((Z,m_p), (e,m), (e,m))$ predicted by F Stillinger has been calculated to be equal to $Z_{B}^{\infty}\ =\ 0.904854$ and $Z_{B}^{m_p}\ =\ 0.905138$ for infinite and finite (proton) mass $m_p$ of charge $Z$, respectively. It is shown that in both cases, the ground state energy $E(Z)$ (analytically continued beyond the critical $Z_c$ to $Z < Z_c$) has a square-root branch point with exponent 3/2 at $Z=Z_B$ in the complex $Z$-plane. Based on analytic continuation, the second excited, spin-singlet bound state of negative hydrogen ion H${}^-$ is predicted to be at -0.515541 a.u. (-0.515311 a.u. for the proton mass $m_p$). The first critical charge for which the ionization energy vanishes is found for a finite proton mass $m_p$ in the Lagrange mesh method, $Z^{m_p}_{c}\ =\ 0.911\, 069\, 724\, 655$.


An approach to the mechanism of action of antibiotics is to ascertain metabolites which are involved directly in the inhibition of the bacterial cell by a specific antibiotic. A simple means of testing involvement of metabolites in antibiotic inhibition derives from the demonstration (Foster and Pittillo, 1953) that complex natural materials, in small amounts, permit growth in otherwise inhibitory concentrations of penicillin, dihydrostreptomycin, aureomycin, chloramphenicol, or teriamycin. Reversal of inhibition caused by certain antibiotics has been reported for specific metabolites, e.g., actathiazic acid by biotin or pimelic acid (Grundy et al., 1952), erythromycin by pantothenic acid, g-alanine or l-carnosine (Brown and Emerson, 1953), chloramphenicol by phenylalanine, tyrosine, tryptophan, or glycine (Woolley, 1950; Mentzer et al., 1950), and streptomycin by pantothenic acid (Lichstein and Gilfillan, 1951). However, in most cases the experiments were conducted in liquid media with relatively heavy inocula, and, from the data presented, proof of reversal is not unequivocal owing to lack of information as to sensitivity of cells in the "reversed" cultures. Theoretical aspects of reversal relative to procedures, with particular emphasis on selection of resistors by complex supplements in liquid media, have been covered in our previous paper (Foster and Pittillo, 1953). The present paper describes experiments on each of the first mentioned five antibiotics listed above in which reversal was tested with various metabolites. The degree of reversal obtained ranged from slight to very marked; even in the case of the latter there was a limit to the reversibility. Deducible from these results is that disturbance of the metabolism of the metabolite


ObjectiveIn this paper,the visualization of craniofacial medical image is studied and a three dimension stereo visualization system based on CT faultage image for implant surgery of craniofacial is presented.MethodUsing the 3D texture mapping method,the 3D craniofacial image can be reconstructed from the CT images.The segmental images which are vertical to X,Y,Z axes of the reconstruction image can be obtained.The eighteen fan-shaped incising images on the orbital position can also be got by using the edge detection method.At last,get the position of the orbit on the image by using edge detection method and then get eighteen fan-shaped images by incising the image.ResultsSurgeons can analyze the osseous tissue and then design the process of the surgery,simulate or forcast the effect of the implant surgery by using the system.ConclusionAnyway,the system is efficient and can be used in practice.


This paper deals with the choice of the motor-transmission couple to drive a joint in the frequent case in which the limit curve of the dynamic operating range of the drive system depends on the motor speed. The paper considers a given drive system and proposes a method that resorts to a succession of instant analyses during the reference task: for a transmission with no energy dissipation the result, if it exists, is a range of transmission ratios that can be coupled with the given motor in order to perform the reference task. The extension of the method to a real transmission is a diagram that correlates the transmission ratio and the direct and inverse efficiency of the reducer and that offers the designer an overview of the transmissions that can be coupled with the given motor to perform the reference task.


This paper uses the methods of hierarchical cluster,divides Hebei province into 3 kinds of gradient areas.Based on above,the paper analyses the character of different regions and proposes the countermeasures of eleven cities.


The effects of Fructooligosaccharide(FOS),Glucooligosaccharide(GOS) and Mannanoligosaccharide(MOS) on diarrhea control and performance of weanling pigs were studied. 48 thirty five day old Duroc×landrace weanling pigs were randomly divided into 4 groups.FOS group,GOS group and MOS group were supplemented FOS,GOS and MOS 3 g,2 g and 3 g per diet respectively.In the course of the experiment for 28 days,weanling pigs were observed;feed intake and body weight per weanling pig were recorded;serm and the whole blood of pigs were collected to be analyzed.The final results showed as below:In group FOS,GOS and MOS, the diarrhea frequency of weanling pigs decreased by percent 66,25 and 54 respectively.The FOS,GOS and MOS had apparent(P0 05) or significant effect(P0 01) on activities of SOD and GSH Px in sermn of pigs.Three oligosaccharides had apparent or significant effect on the number of T lymphocyte(CD 3) and IgG content in peripheral blood.Daily gain of piglets and feed conversion efficency increased in treatment groups.


In citizen science, citizens are encouraged to participate in research, with web technologies promoting location-independent participation and broad knowledge sharing. In this study, web technologies were extracted from 112 citizen science projects listed on the "Bürger schaffen Wissen". Four indicators on web technologies—Online platforms, Educational tools, Social media, and Data sharing between projects—were chosen to quantify the extent to which web technologies are used within citizen science projects. The results show that the use of web technologies is already very well established in both the natural and social science projects and only the possibilities for data sharing between projects are limited.


DOI:10.1097/MOL.0000000000000151 The link between triglyceride levels and cardiovascular disease was first described several decades ago. Several high-quality observational studies and clinical trials [1,2 & ,3–5,6 && ,7,8] have since demonstrated that elevated levels of triglycerides are associated with an increased risk of cardiovascular disease, myocardial infarction, stroke and all-cause mortality, even after LDL cholesterol (LDL-C) therapeutic goals have been achieved. This evidence base was recently bolstered by two large genetic studies [9,10] that linked loss-offunction or missense mutations in apolipoprotein C3 [APOC3; a protein that normally inhibits lipoprotein lipase (an enzyme responsible for the hydrolysis of triglyceride-rich lipoproteins)] to reduced cardiovascular risk. The first of these studies [9] utilized data from individuals enrolled in two large Danish observational studies (the Copenhagen City Heart Study and the Copenhagen General Population Study; 75 725 individuals in total). Using DNA sequencing and mutational analysis, Jørgensen and colleagues identified three key loss-of-function or missense mutations in the APOC3 gene: R19X, IVS2þ1G!A and A43T. Heterozygote carriers of any of these mutations (occurring at a frequency of 1 in 290 patients) had, on average, 44% lower plasma triglyceride levels than noncarriers [9]. Moreover, the risk of developing coronary or vascular disease in APOC3 heterozygotes was significantly lower than that observed in noncarriers [hazard ratio (HR) 0.64 (95% confidence interval (CI) 0.41–0.99) and 0.59 (0.41–0.86), respectively]. Similar findings were obtained in the second study [10], which drew on data from the Exome Sequencing Project and 15 large cohort studies. In addition to the three loss-of-function mutations reported by Jørgensen and colleagues, exome sequencing identified a fourth APOC3 mutation, IVS3þ1G!T, which also was associated with reduced plasma triglyceride levels. Carriers of any of the four APOC3 mutations had significantly lower triglyceride levels than noncarriers ( 39%), and a lower risk of coronary disease (HR 0.60, 95% CI 0.47–0.75) [10]. An analysis of the relationship between APOC3 levels and incident cardiovascular


ABSTRACT The objectives of this study are: 1) To determine the contribution of the effect of the APBN Balance Fund on infrastructure development in Jombang Regency. 2) To find out the contribution of the Bumi Bangunan (PBB) tax compared to other regional revenues on infrastructure development in Jombang Regency. This research uses descriptive research. Descriptiv 0 research is research conducted to determine the value of an independent 0 variable, either one variable or more without 0 making comparisons or connecting with other variables. The results of this study indicate that: 1) Contribution of the State Budget Balancing Fund to Infrastructure development in Jombang Regency. 2) Contribution of Land and Building Tax (PBB) compared to other regional income towards infrastructure development in Jombang Regency. This shows that the contribution of the APBN balance fund and the land and earth building tax (PBB) is very effective. Keywords: APBN Balancing Fund and Land and Building Tax (PBB)


Dibromodulcitol treatment induced histological damages in solid Ehrlich carcinoma which increased on the effect of parallelly applied local fractionated X-irradiation. Comparing the effect of differently fractionated irradiations of the same total dose combined with dibromodulcitol treatment it can be stated that daily applied low radiation fractions cause more severe histologically demonstrable damage than relatively higher ones given in three to four day intervals.


Since the early days of space exploration, the unique vantage point of space has been used for observing the Earth as a system.


Optimal nutrition may prevent dementia; several nutrients have been associated with dementia risk, yet randomized controlled trials (RCT) testing the efficacy of nutrient supplementation for the prevention of dementia have remained largely disappointing so far. One of the reasons for the inability of RCT to demonstrate the efficacy of nutrient supplementation may be their failure to take into account basal nutritional status (as supplementation may benefit only people with nutrient deficiency). Epidemiology is a unique tool to understand and define the basal nutritional deficiencies that may primarily deserve correction with (multi)‐nutrient supplementation. We leveraged the large prospective French Three‐City (3C) cohort study, with multiple nutrient biomarkers measured at study entry and 17 years of follow‐up for the incidence of dementia, to define a micro‐nutritional biological status (MNBS) score that is associated with subsequent dementia risk.


Proliferation of digital libraries plus high availability of electronic documents from the Internet have created new challenges for computer science researchers and professionals. This paper discusses the problems of using par- allel and cluster computing systems for detecting plagiarism in large collections of semi-structured electronic texts, including software written in formal lan- guages at one end of the spectrum and natural language texts at the other end. The main component of the system is using string matching algorithms and suffix trees. Implementation and performance issues are also discussed.


COMRA (China Ocean Mineral Resources Association) registered pioneer area (CRPA) is located in the western part of the area between the Clarion and Clipperton Fraction Zones (CCFZs). Based on distinctive color and bio-disturbing properties, two layers are recognized in the sediment columns from the CRPA: a pale brown layer (Unit A) on the top and a dark brown layer (Unit B) in the lower part. Color division between them can be explained as a hiatus. As a result, the two units are different to each other in chemical composition and sediment properties. It is found that contents of P 2 O 5 , MnO 2 , CaO, Na 2 O in sediments of older Unit B are higher, but SiO 2 content is slightly lower. Based on correlation analysis, Mn and Fe in the sediments have different origins. The former is mainly precipitated in authigenic process, whilst the latter is closely related to terrigenous detritus. Therefore, the differences in chemical composition of the sediments are caused by different sedimentation settings.


Resource occupier (e.g., data, people) available resources (e.g., bandwidth, radio frequency spectrum, theater seats) for automatically allocated to the method, apparatus, system, and program providing for computer It is. Allocation of resources to the resource occupier, the size of the resource occupier, available resources, and is calculated resources from the remaining time to be allocated to the resource occupier is based on the indication of the urgency of allocation. One, two, or more time threshold, in particular, timeliness threshold (assigned urgency until it increases and decreases too this), and perishability threshold (but past this resource occupier resource allocation to is no longer useful at all, then the resource can not be allocated) may be associated with each resource occupier. For real-time allocation of radio frequency spectrum, the method of automated auction system, and program may be provided.


The DSM, or Dispute Settlement Mechanism, in the absence of a judicial body, is the closest representation of a supreme court or judicial institution in a regional bloc or other international organisation. The search for a peaceful settlement of disputes in the international arena had led to the development of the DSM during the 20th and into the 21st century. The DSM acts as an impartial third party, wherein it intervenes in any international conflict to offer feasible solutions for both sides.


The paper has two main objectives. First, to investigate whether workers show significant differences in labour opportunities. Second, to test the hypothesis that tertiarisation has important effects explaining it. The hypotheses are: (1) tertiarisation has relevant effects on the structure of labour demand by skills; (2) the labour opportunities of workers can be influenced by the skills developed in their previous jobs and their concordance between sectoral changes. From a methodological point of view, the approach implies a study of labour transition data of workers, sectoral change and its qualification implications. In order to research the previous argument, the authors analyse labour mobility within European countries. Therefore, data used in the paper come from the European Community Household Panel (ECHP). All descriptive analyses have been carried out and the results from dynamic logit panel data model suggest that the relation of workers to tertiarisation and its implications – approximated by their previous labour situation (sector and skill) – are significant, explaining differences observed in labour transitions and its characteristics.


A new technique to compute the physical optics (PO) integral is presented. The technique consists of a blind code that computes the different contributions (stationary phase points, end points, etc.) numerically. This technique is based on a decomposition of the surface into small triangles and a fast evaluation of each triangle by means of a deformation of the integration path in the complex plane. This algorithm permits a fast and accurate evaluation of the PO integral for smooth large surfaces. The CPU time is almost independent of frequency.


A stage property lift with an improved structure is provided to more efficiently and stably lift properties of a stage, to minimize the space for installing the lift and to prevent a sudden fall of a wire during an emergency. A stage property lift(100) includes a motor; a brake block(110) having a first and a second brake(111,112) for braking the motor; a decelerating and driving power transfer block(120) having a motor(121) and a decelerator(124) connected in one unit; a cylindrical shaped wire driving axis(130) with one end being connected to the decelerating and driving power transfer block and the other end being supported by a bearing; an encoder for sensing a rotation speed of the wire driving axis(130); and a brake controller for judging an error in the first brake(111) based on the rotation speed of the wire driving axis and actuating the second brake(112) if there is an error in the operation of the first brake.


In a recent note W. Kohnen asks whether the values of Dedekind sums are dense in the field of $p$-adic numbers. The present paper answers this question. Dedekind sums do not approximate units of $\mathbb Z_2$ or $\mathbb Z_3$, so they are not dense in $\mathbb Q_2$ or $\mathbb Q_3$. But they are dense in $\mathbb Q_p$ if $p\ge 5$.


At present, 5 1/2" casing withdrawal and replacement operation often leads to a large hole diameter and 90mm of clearance between wall and casing, which brings about a lower displacement efficiency and an uncertain cementing quality. For this reason , many more studies have been made, including displacement fluid flow, displacement pressure, critical pumping rate and fluid characteristics etc, and low density slurry is finally determined to be a turbulent spacer pad. An in-situ treatment program has also been developed. Furthermore, in order to reduce cement sheath setting time and increase the expansion ratio, cement additions have been tested and selected and a new cement formula has been developed. The field result indicates that the average cement bond index was increased by 32% and the cementing quality was improved.


According to the vibration phenomenon happening to the rolling mill with AC-AC frequency conversion to control speed at the time biting and casting steel,the reasons of torsional vibration is analyzed. On the basis of the analysis,we get disturbance by torque sensor then compensate the torque component of stator current and the magnetizing current to keep the motor torque constant. The theoretic analysis was tested by simulink,and we get three sets of curves: the curve of torsional,the curve of speed and curve of the torque component of stator. All results meet the expectations. At the last,its feasibility was analyzed.


Teacher's morality insists on teacher's lofty moral standard,emphasizes teacher's and student's harmony,and helps students to change their moral behavior,reflecting humanist aspect of traditional teacher's morality.But too great standard downgrades its guiding role in teacher's morality and bring much trouble to student's subjectivity.Thus,by returning teacher's identity to natural person,enforcing the ethics principle with equality and dialogue and insisting on humanity in teacher's morality,the humanity of teacher's morality can be promoted and traditional teacher's morality can be transferred to modern teacher professional ethics.


: The study, throughout two years (2004 and 2005), of different systems of soil management, as well as different basal leaf removal modalities, effects on the white variety 'Fernão Pires', took place in a vineyard pertaining to Sogrape Vinhos, SA, located in the Bairrada Demarcated Region (littoral/centre of Portugal). Two techniques of soil management between rows were applied: the permanent natural grass cover and tillage, both with application of herbicide on the row. In 2004, basal leaf removal was carried through at veraison on the two sides of canopy or only on the East side. In 2005, other basal leaf removal modalities were introduced, at pea size or at veraison, applied only on one or two faces of canopy. In the two years of the experiment, the climate during the vegetative cycle was dry, especially in 2005. In consequence the predawn leaf water potential reached very low values along ripening and differences between grass covered and tilled treatments have not been registered. Higher net photosynthetic rates were obtained in tilled treatment, probably due to greater magnesium content in the leaves. Grass cover conduced to a less dense canopy, especially in 2005, by a reduction of the leaf layer number (LLN), higher penetration of photosynthetically active radiation (PAR) at cluster zone and in 2005, provoked a drastic increase on the proportion of sunburned leaves and scalded clusters. On the other hand, basal leaf removal also modified the canopy structure, reducing its density, particularly in 2004. In this year, high bunch rot ( Botrytis cinerea L.) incidence occurred and the reduction of canopy density had an important role on it's the decrease. In 2004, yield components hadn't been significantly affected by any of the factors in study. However in 2005, although basal leaf removal haven't influenced yield, grass cover strongly reduced it (about 50%). Vigour reduction was verified in both years only by grass cover. Small differences between treatments were found in what concerns to must composition. At harvest in 2005, soil management techniques didn't influenced nutritional cluster composition.


Pneumonia is a high mortality disease that kills 50, 000 people in the United States each year. Children under the age of 5 and older population over the age of 65 are susceptible to serious cases of pneumonia. The United States spend billions of dollars fighting pneumonia-related infections every year. Early detection and intervention are crucial in treating pneumonia related infections. Since chest x-ray is one of the simplest and cheapest methods to diagnose pneumonia, we propose a deep learning algorithm based on convolutional neural networks to identify and classify pneumonia cases from these images. For all three models implemented, we obtained varying classification results and accuracy. Based on the results, we obtained better prediction with average accuracy of (68%) and average specificity of (69%) in contrast to the current state-of-the-art accuracy that is (51%) using the Visual Geometry Group (VGG16 also called OxfordNet), which is a convolutional neural network architecture developed by the Visual Geometry Group of Oxford. By implementing more novel lung segmentation techniques, reducing over fitting, and adding more learning layers, the proposed model has the potential to predict at higher accuracy than human specialists and will help subsidies and reduce the cost of diagnosis across the globe.


The major al)ergen (1leir c 1) in the muscle of the gastroped, 1letrbo cornutus, was isolated by Sephacryl S-3oo, Mono Q HR 5/5 and TSKgel Phenyl-5PW RP column chromatography. ELISA shewed 7leir c 1 to react strongly with sera from three individuals sensitive to both mo]lusks and crustaceans. SDS-PAGE showed Iletr c 1 to produce a major band corresponding to a molecular mass of 35 kDa llnder the reduced condition. Its amino acid cemposition


The article proposes a conceptual framework with empirical foundations, prerequisites, theoretical foundations and implementation, and validity criteria. It also presents methods to improve transport and interchange hubs on the example of the St. Petersburg agglomeration, aimed at improving the efficiency of hubs operation, developing infrastructure and stations, improving the capacity of the transport network, achieving uniform loading system and traffic safety, increasing the attractiveness of rail transport for the population, increasing the index of passenger satisfaction. The analytical review of normative documents, theoretical provisions, programs and measures, carried out and planned for implementation for the development of St.-Petersburg railway junction has been made. The existing models of transport-transfer hubs in the St.-Petersburg agglomeration were investigated and the directions for their improvement were revealed by creating the concept. On the basis of the proposed synergistic-logistic concept, the provisions to ensure the improvement of transport-transfer hubs (on the example of the St. Petersburg agglomeration) have been developed.


The display and transplant of Chinese font library are difficult in embedded GUI.The compatibility of font libraries is the trend of internationalization in one system.So Chinese software is a typical application in the design of embedded system.How to improve the function that different font libraries can be used in the same embedded GUI is the whole point to study.Through analyzing Chinese font library based on Qt/Embedded and relationship of different Chinese characters,a method how to design a special font library with different font code is given.Then local embedded GUI is realized.


Reaction of [MoH4(dppe)2](1)(dppe = Ph2PCH2CH2PPh2) with allyl alkyl carbonates R′O2COCH2CHCH2(R′= Me or Et) in benzene under irradiation with a high-pressure mercury lamp afforded [MoH(O2COR′)(dppe)2](2) together with propene and H2. The seven-co-ordinate complexes (2) were characterized spectroscopically as having a pentagonal-bipyramidal structure in solution and the X-ray crystal structure of (2; R = Et) has been determined: triclinic, space group P with a= 16.400(6), b= 18.828(7), c= 11.821 (3)A, α= 96.22(3), β= 99.47(3), γ= 128.76(2)°, Z= 2, and R= 0.057. It has a very distorted pentagonal-bipyramidal geometry with the two phosphorus atoms, hydride, and two oxygens of the carbonate ligand comprising the pentagonal girdle, in which the last two ligands are mutually trans.


Author(s): Can, Sinan | Advisor(s): Yildiz, Ahmet | Abstract: The ability of cytoskeletal motors to move unidirectionally along linear tracks is central to their cellular roles. While kinesin and myosin motor families have members that move in opposite directions, all dyneins studied to date exclusively move towards the microtubule minus-end. The source of dynein's directionality remains as the central unresolved question about the mechanism of its motility. In my doctoral work, I focused on understanding the underlying mechanism of dynein's directional motility along the microtubules in three dimensions. I used a protein engineering approach, guided by all-atom molecular dynamics simulations and high-resolution cryoEM imaging, along with the tools of single-molecule biophysics to dissect the elements of dynein motility. We successfully engineered a plus-end-directed dynein for the first time and revealed the mechanism of its directionality. This work has three major outcomes. First, by altering the length of the coiled-coil stalk that connects the dynein motor domain to the microtubule, we controlled the handedness of the helical motility of dynein around the circumference of the microtubule. This experiment showed that the stalk length of native dynein is critical for restricting sideways movement and directing dynein motility along the microtubule axis. Second, we altered the angle and length of dynein's stalk. Remarkably, these modifications reversed the direction by which the linker swings relative to the microtubule and directed the motility towards the plus-end. Finally, similar to native dynein, the plus-end directed mutant maintains its preference to release from the microtubule when pulled towards the minus-end by an optical trap. Our results provide direct evidence for the linker swing model in which the direction the linker swings determines the direction of dynein motility. Our results also rule out the asymmetric release model that the directionality is proposed to be determined by the direction dynein favors for release from the microtubule under tension. Two critical features of dynein's stalk, the length of its antiparallel coiled-coils and two proline residues located at its base, control the directionality by directing the linker swing towards the MT minus-end. Because both features of the stalk are fully conserved in cytoplasmic and ciliary dyneins across species, this mechanism explains the minus-end directionality of all dyneins.


A. On a principle of flexibility of scientific truth -- From a deeper scrutiny of the foundations of scientific truth it follows that every scientific statement referring to observations should possess a certain minimum degree of flexibility. In other words, no set of two-valued truths can be established with the expectation that this set ultimately will stand the test of experience. Formulations of scientific truth intrinsically must be many-valued.


This paper introduces a novel joint channel-aware and queuing-aware OFDMA scheduler for delay sensitive traffic based on a Hopfield Neural Network scheme. It allows providing an optimum OFDMA performance by solving a complex combinational problem. Some illustrative results on the dropping rate and delay have been obtained for a delay- sensitive service modelled as www traffic. These results, shown for comparison purposes, outperform significantly those obtained for a conventional heuristic scheduling.


Vietnam has abundant and diversified mineral resources with more than 5, 000 mines of 60 discovered and exploited minerals. Besides of surface coal mines mainly located in Quang Ninh, the types of minerals being exploited by surface mining method consist of metal ores (iron, titanium, manganese, gold, zinc, copper, antimony) and non - metallic ores, and construction materials (stone, sand, gravel, etc.). In the paper, authors researched and proposed the advanced technologies and equipment based on Industry 4.0, that can apply effectively for surface mines in Vietnam in order to ensure safety and enhance surface mining effect.

http://jmes.humg.edu.vn/images/paper/2020/61_5/KTLT/2. Tran Quang Hieu 16-32.pdf


The damascene technology is widely used for Cu interconnect structures in integrated circuits. Due to the strong variation of the feature sizes and densities of Cu interconnect lines and contact pads involved in electromigration (EM) test structures, the CMP of the excessive Cu layer is very complicated. This paper will present the challenges of removing of Cu and Ta by CMP and the successful application of well prepared Cu interconnects in life-time experiments.


Permanent magnet brushless DC motors finds wide applications in industries due to their high power density and ease of control. These motors are controlled using a three phase power semiconductor bridge. This paper deals with a novel control technique based on PWM & PAM control of brushless DC motor (BLDC). For inverter-controlled Brushless DC Motor (BLDC) drives, the inverter can be controlled by either Pulse-Width Modulation (PWM) technique with a constant DC link voltage or Pulse-Amplitude Modulation (PAM) technique. PAM modulates the inverter power devices using 120-degree modulation technique and controls the amplitude of the DC link voltage. The results show that Pulse amplitude modulation control improves the speed performance of BLDC motor at high speeds. The simulation results of BLDC motor drive with PWM & PAM control techniques are shown in the MATLAB/Simulink environment.


Background: University students being energetic, active, and robust engage proactively in their lives. Students' coping styles are important to deal with daily life issues. The current study investigated the mediating role of coping style between social support and psychological well-being among students of Karachi University, Pakistan. Method: To test the hypotheses, a sample of 105 university students (males 51 & females 55) with the age ranging between 19 to 36 years (mean age= 24.85; SD=.478) belonging to different socioeconomic status were selected from the University of Karachi, Pakistan. After taking permission from HOD of concerned departments, Demographic Information Form, Multidimensional Perceived Social Support Scale Coping styles scale, and Psychological Well-Being Scale were administered on participants in group settings. Descriptive statistics, correlation analysis, and Hayes' PROCESS macro and bootstrap analysis were performed.Results: Problem-focused coping contributes 18 % variance in the psychological well-being of university students. Moreover, Social support brings 35 % and 46 % variation in the relationship of problem-focused coping; emotion-focused coping, and psychological well-being.Conclusion: Problem-focused coping was shown as an important mediating factor for social support and psychological wellbeing.


A mathematical model of the vertical screw conveyer loading has been proposed. Algorithm of solution of the differential equations with partial derivatives of the bulk-cargo medium movement in the screw channel has been developed. Taking advantage of the proposed model it makes possible to develop new designs of the screw conveyer intake devices and to interpret their efficient parameters.


Objective To observe the changes of serum TNF-α,IL-6 Levels in patients with obstructive sleep apnea-hypopnea syndrome(OSAHS) and investigate their clinical significance in the occurrence of OSAHS-related cardiocerebral vascular diseases.Methods Following polysomnographic examination,208 adult male patients were divided into 4 groups: 30 with simple snorers,45 with mild OSAHS,65 with moderate OSAHS,and 68 with severe OSAHS.The serum levels of TNF-α and IL-6 of all the patients were determined by enzyme linked immunosorbent assay(ELISA);the correlations between TNF-α(or IL-6)and other factors were analyzed;the incidence of cardiocerebral vascular diseases for each group was calculated.Patients with moderate or severe OSAHS were divided into 2 groups: nasal-continuous positive airway pressure(nCPAP) group and control group,and received further follow-up.After 2 months' follow-up,their serum levels of TNF-α and IL-6 were determined.Results Serum levels of TNF-α and IL-6 both increased with exacerbation of OSAHS,which was most significant in patients with severe OSAHS.Serum TNF-α and IL-6 Levels were correlated positively with AHI and tSpO290%,and negatively with MeanSpO2 and MinSpO2.The incidence of cardiocerebral vascular diseases increased with OSAHS Exacerbation.After 2 months' follow-up,there was a significant decrease in serum levels of TNF-α and IL-6 in nCPAP group while there were no similar changes in the control group.Conclusion Serum levels of TNF-α and IL-6 and the incidence of cardiocerebral vascular diseases are significantly increased in OSAHS patients.Increased serum levels of TNF-α and IL-6 may lead to the associated cardiocerebral vascular diseases.Effective nCPAP therapy may help decrease serum levels of TNF-α and IL-6 and reduce the associated cardiocerebral vascular diseases in OSAHS patients.


Active case finding for tuberculosis (TB) has not historically been part of the WHO's TB control strategy because prior studies have suggested that people with TB symptoms seek care, but aren't diagnosed. Identifying whether blocks to case detection occur because patients don't seek care or providers don't diagnose TB is crucial to success of a program. This pilot study evaluates whether people with TB symptoms in the high-incidence Brazilian favela, Rocinha, seek care. Methods: Community health agents performed door-to-door TB symptom screens in a pilot area of the favela using standardized data collection tools. Factors potentially affecting care- seeking behavior were evaluated, including gender, age, history of TB, contact status and duration of cough. Interactions were assessed. Univariate analysis and GEE were performed in STATA 8. Results: 3385 people in 1172 houses were surveyed. Of 324 people reporting cough, 43(13%) ac- knowledged seeking help for their symptoms. Of 102 people with a cough of 3 or more weeks, 22 (22%) had sought care. Of variables mentioned above, only age under 6 (p ¼ 0.002, 95% CI 1.73, 10.61) and duration of cough (3 weeks or more) (p ¼ 0.001, 95% CI 1.59, 6.71), were statistically significant. Discussion: Mathematical models of TB have shown that increased case finding and earlier treatment will reduce the overall burden of disease. Results from this pilot study show that in this favela setting, adults, who are more likely to transmit infection than children, are not seeking treatment for their respiratory symptoms. Increasing case detection in symptomatic adults will be of value in this setting. A ten folds higher incidence rate of tuberculosis (TB) among indigenous Taiwanese (IT) than other Taiwanese has been observed, despite past three decades of continuing TB control efforts from Taiwan government. Reasons for lack of efficacy in TB control among ITare not clear. While most efforts to improve TB control in this population continue to focus on medical services, this study explored socio-cultural impediments to TB care and proposed strategies to overcome these obstacles. Obstacles to the control of TB among IT were identified through anticipation observations and inter-view with 18 local medical professionals and educated community mem- bers. Transportation and financial difficulties delayed care-seeking behaviors among IT, leading to prolonged infectious periods in the com- munities. Alcohol dependence commonly interfered with medication ad-herence. High turnover of local health staffs impeded the relationship between health professionals and the aboriginal communities, reducing the effectiveness of public health messages about TB and the ancillary treatment supports. Interestingly, churches were important sources for IT to receive health education. Since 75% of ITaccept Christianity or Cathol- icism as their religious belief and churches are located in every aboriginal community, cooperation with local churches is a feasible strategy to en- hance aboriginal awareness and acceptability of TB control measures. Sev-eral supplementary measures, such as free day-care, should be considered to eliminate the obstacles of affected IT in seeking TB care. Unique cultural and socioeconomic factors should be considered in order to create TB control programs sensitive to aboriginal needs. Background: Objective: of COPD and asthma in an elderly population. Study Design: Cohort study with sequence sym- metry analysis. Setting: Medicare beneficiaries who received drug coverage through the Pennsylvania Pharmaceutical Assistance Contract for the El- derly between 1997 and 2002. Patients: Two cohorts of patients, both with history of COPD or asthma. One cohort of 922 patients initiated AChE-I; the other cohort of 2,819 patients initiated beta-blockers, a comparison drug also contraindicated in COPD and asthma. Main Outcome Measures: The occurrence of four outcomes in claims data: 1) emergency room visits for acute exacerbation of COPD (AECOPD), 2) hospitalizations for AECOPD, 3) physician visits for AECOPD, and 4) antibiotic and oral corticosteroid dispensings on the same day. Results: Initiators of AChE-I had no detect- able increased rate of AECOPD upon treatment initiation. Rate ratios (RR) of the four outcomes ranged from 1.00 (95% confidence interval ¼ 0.61, 1.62) to 1.64 (0.55, 4.89), none reaching statistical significance. In contrast, beta-blocker initiators had significantly increased rates of all four outcomes following treatment initiation, with RR ranging from 1.97 (1.18, 3.29) to 2.76 (1.71, 4.45). Conclusion: These results suggest that in current clinical practice, physicians prescribe AChE-I safely to elderly patients with COPD or asthma, while beta-blocker prescribing continues to result in adverse health outcomes.


TPS129 Background: Insulin-like growth factor (IGF) signaling has been implicated as a mechanism of resistance to therapies targeting the HER2 pathway in breast cancer, such as trastuzumab and lapatinib. Cixutumumab (IMC-A12) is an IgG1 monoclonal antibody that binds IGF-1 receptor (IGF-1R), blocking ligand activation of the IGF system and stimulating receptor down-regulation. The addition of cixutumumab to capecitabine and lapatinib in HER2+ breast cancer may improve the clinical benefit of this regimen. Methods: N0733 is CTEP-sponsored, NCCTG-led, multicooperative group supported randomized phase II trial investigating the clinical activity of capecitabine plus lapatinib ± cixutumumab. Patients with advanced or metastatic HER2+ breast cancer treated previously with trastuzumab and an antracycline and/or a taxane with measureable disease and adequate organ function are eligible for participation. Following an initial safety cohort testing the safety and tolerability of cixutumumab in combination with cap...


The article presents the results of a comparative assessment of grain productivity and adaptability indicators of various varieties of yellow lupine cultivated on soddy-podzolic sandy soil. We studied 8 varieties of lupine of domestic selection of the All-Russian Research Institute of Lupine, Novozybkovskaya SHOS; neighboring countries - Belarus and foreign selection (Germany), as well as the hybrid material of the Novozybkovskaya SHOS for 2016–2020. The adaptability of variety samples was comprehensively tested in terms of environmental stability and plasticity, using the criterion of "yield". Changes in meteorological conditions over the years of research made it possible to objectively assess the variation in the productivity of lupine by grain. For five years of testing, the grain yield varied from 6.4 c/ha Vladko (Belarus) to 11.8 c/ha, Novozybkovsky 100 (Novozybkovskaya SHOS). On average, changes in the productivity of varieties of VNII lupine from 9.7 to 11.3 c/ha, Novozybkovskaya SHOS – 10.7–11.8 c/ha, Belarusian breeding – 6.4–9.1 c/ha, foreign – 8.3–8.7 q/ha. Samples 5-10-84 (13.2 c/ha), 1-08-7-75 and 2-13-33 (12.7 c/ha) and 7-13-65 (12,5 q/ha). According to the set of indicators of adaptability, the All-Russian Research Institute of Lupine Nadezhny and Bulat turned out to be the best among the varieties; Belarusian selection Kastrychnik; Novozybkovskoy SHOS – Druzhny 165 and Novozybkovsky 100. From the hybrid material of the Novozybkovskaya SHOS promising numbers 1-08-7-75, 5-10-84, 4-12-302, 2-13-33, which have genetic flexibility, adaptability and stability in conditions of sandy and sandy loamy soils of the South-West of the Bryansk region.


Recently, for a number of reasons, retail and office premises on the first floors of the building, which have a separate entrance to the street, have gained wide popularity. These rooms must have supply ventilation to maintain the required microclimate parameters. The article proposes, in addition to fulfilling its main function, to use general exchange ventilation as an air curtain in these types of premises. Due to the supply of air above the doorway with certain parameters, in some cases, it is possible to abandon the thermal air curtain as a separate energy-intensive device. The implementation of this task is supposed to be carried out by organizing the necessary air exchange scheme, without increasing its required performance. The article presents the results of the study, which make it possible to assess the possibility of using the proposed technical solution for the most standard case. In particular, an adapted calculation of the air distribution grille is presented to fulfill the stated purpose.


We prove the following results: (1) for any nonsingular projective $3$-folds $X$ of general type with $\chi(\mathcal{O}_X)\neq 2,3$, the canonical volume $\text{Vol}(X)$ has the optimal lower bound $\frac{1}{420}$; (2) for nonsingular projective $3$-folds (resp. $4$-folds) $X$ of general type with $h^{2, 0}(X)\geq 108\cdot 42^3+4$ (resp. with sufficiently large $h^{2, 0}(X)$), the $3$-canonical map (resp. $5$-canonical map) is stably birational; (3) for any nonsingular projective $n$-fold $X$ of general type with $q(X)>n\geq 4$, the canonical stability index $r_s(X)$ is upper bounded by the $(n-1)$-th canonical stability index $r_{n-1}$.


Galacto-type trehalose, a "C-4 epimer of trehalose", possesses a stereochemical structure around the alpha(1-1)-linkage analogous to that of the globobiosyl alpha(1-4)-linkage in Gb(2) and Gb(3) ceramides, which are known as the ligands of Shiga toxins produced by pathogenic E. coli. This paper presents evidence supporting the new idea of using a trehalosyl alpha(1-1)-linkage as a substitute for the galactobiosyl alpha(1-4)-linkage.


This study aims to determine: 1) the effect of the application of the game magic box on the language development of children aged 5-6 years; 2) the effect of the quiz / question and answer method on language development of children aged 5-6 years; 3) differences in the application of the game  magic box  with question and answer method for language development of children aged 5-6 years at RA Al-Fajar Medan Denai. The method used is quantitative research, the type of research is quasi experimental design using post-test design control group design (non equivalent control group design).  The population is 26,  namely 13 children of class B1 (experimental class) and 13 children of class B2 (control class). The results of this study are 1) The influence of the application of the game magic box on language development of children aged 5-6 years, seen from the calculated value = 10.2700> table = 2.064; 2) The influence of the question and answer method on the development  the language of children aged 5-6 years, seen from the calculated value = 8.6782> table = 2.064; 3) There are differences in the influence of the application of the magic box (mystery box) with the quiz / question and answer method on the language development of children aged 5-6 years in  RA Al-Fajar Medan Denai, seen from the calculated value = 2.7458 and table = 2.064.


This study explores the concept that ethnic groups have different motivations and crowding norms when downhill skiing and that visiting and immigrant ethnic groups would respond more like their original ethnic group than they would be like their host ethnic group. The four ethnic groups or sampling strata that were surveyed in this study were: White Anglo skiers at Hunter Mountain Ski Area; Korean skiers at Hunter Mountain Ski Area; White Anglo skiers at Yong Pyeong Ski Resort; and Korean skiers at Yong Pyeong Ski Resort. The total sample was 1,157 skiers for the four sampling strata. Eight hypotheses were tested to explore what affect the ethnic differences of skiers had on motivations for skiing and crowding norms for White and Korean skiers in New York State and Korea. Discriminant analysis was used to predict group classification in the four sampling strata based on the eight variables used in the hypotheses testing.


A 2–2 cascaded switched-capacitor <inline-formula> <tex-math notation="LaTeX">$\Sigma \Delta $ </tex-math></inline-formula> modulator is presented for design of low-voltage, low-power, broadband analog-to-digital conversion. To reduce power dissipation in both analog and digital circuits and ensure low-voltage operation, a half-sample delayed-input feedforward architecture is employed in combination with 4-bit quantization, which results in reduced integrator output swings and relaxed timing constraint in the feedback path. The integrator power is further reduced by sharing an op amp in the two integrators in each stage and periodically changing the op amp bias condition between a high-current and a low-current mode using a fast low-power high-precision charge pump circuit. Implemented in a 0.18-<inline-formula> <tex-math notation="LaTeX">$\mu \text{m}$ </tex-math></inline-formula> CMOS technology, the experimental prototype achieves a 92-dB dynamic range, a 91-dB peak signal-to-noise ratio, and an 84-dB peak signal-to-noise plus distortion ratio, respectively for a signal bandwidth of 1.25 MHz. Operated at a 40-MHz sampling rate, the modulator dissipates 24.3 mW from a 1 V supply.


1. Introduction: Representing the Place of Culture Part 1. On Representation in Cultural Geography 2. Author and Authority: Writing the New Cultural Geography 3. Sites of Representation: Place, Time and the Discourse of the Other 4. Spectacle and Text: Landscape Metaphors in Cultural Geography 5. The Lie that Blinds: Destabilizing the Text of Landscape Part 2. On Representing Residential Landscapes 6. Re-Valuing the House 7. Public Housing in Single-Industry Towns: Changing Landscapes of Paternalism 8. Co-Operative Housing as a Moral Landscape: Re-examining "the Postmodern City" 9. Myths and Meanings of Gentrification Part 3. On Representing Institutional Cultures 10. "This Heaven Gives Me Migraines": The Problems and Promise of Landscapes of Leisure 11. The Department of Indian Affairs and Northern Development: the Culture Building Process within an Institution 12. Multiculturalism: Representing a Canadian Institution 13. Representing Power: The Politics and Poetics of Urban Form in the Kandyan Kingdom Part 4. On Representing Cultural Geography 14. Representing Space: Space, Scale and Culture in Social Science 15. Interventions in the Historical Geography of Modernity: Social Theory, Spatiality and the Politics of Representation 16. Reading, Community and a Sense of Place 17. Epilogue


The global pandemic of the BA.5 subvariant had moved from prediction to reality. In this study, we compared SARS-CoV-2 aerosol emissions from patients with BA.2 or BA.5 subvariant infection. First, patients with BA.2 subvariant infection had higher upper respiratory viral loads than patients with BA.5 subvariant infection. However, the average breath emission rate (BER) of patients with BA.5 subvariant infection, which represented the concentration of exhaled SARS-CoV-2 aerosols, was nearly 40 times higher than that of patients with BA.2 subvariant. Second, aerosols exhaled by patients with BA.5 subvariant infection exhibited SARS-CoV-2 RNA detection positive rate than patients with BA.1 or BA.2 subvariant infection. Meanwhile, for BA.5 subvariant infection, patients that exhaled infectious SARS-CoV-2 aerosols accounted for 14.8% of all patients. Third, since the onset of COVID-19, the SARS-CoV-2 RNA detection signals of throat swabs showed a gradual decline trend, although the decline process was accompanied by fluctuations. Overall, the monitoring of infectious SARS-CoV-2 aerosols may provide the data support for the transmissibility evaluation of the Omicron BA.5 subvariant. This article is protected by copyright. All rights reserved.


INTERACTIONS BETWEEN PIERIS OLERACEA AND PIERIS RAPAE (LEPIDOPTERA: PIERIDAE) BUTTERFLIES, AND THE BIOLOGICAL CONTROL AGENTS COTESIA GLOMERATA AND COTESIA RUBECULA (HYMENOPTERA: BRACONIDAE). FEBRUARY 2013 MEGAN V. HERLIHY, B.S., PROVIDENCE COLLEGE M.S., UNIVERSITY OF MASSACHUSETTS AMHERST Directed By: Dr. Roy G. Van Driesche Pieris oleracea, formerly Pieries napi, was once a widespread pierid butterfly in New England until the introduction of a biological control agent, Cotesia glomerata. It has been suggested that C. glomerata is responsible for the range reduction of P. oleracea. There are been several introductions of a second more specialized biological control agent, Cotesia rubecula, to the United States since the 1960's. My first goal was to determine the current distribution and status of P. rapae parasitoids and the effectiveness of C. rubecula as a biological control agent since its release. The findings of a survey I conducted of the parasitoid community of P. rapae indicate that C. rubecula now occurs as far west as North Dakota and has become the dominant parasitoid of P. rapae in the northeastern and north central United States and adjacent parts of southeastern Canada, where it has displaced C. glomerata, the previously dominant parasitoid. Survival of artificially established cohorts of P. rapae larvae was assessed in a collard patch on an organic vegetable farm in western Massachusetts. There was a significant drop in larval survival between the 4 and 5 instar due to parasitism by C.


Pierson syndrome (microcoria – congenital nephrosis) is a recently described autosomal recessive genetic disorder caused by mutations in the LAMB2 gene. A mutation of the LAMB2 gene is the fourth most common detectable genetic mutation in infants with congenital nephrotic syndrome. Pierson syndrome presents in the neonatal period with congenital nephrotic syndrome and ophthalmologic findings of bilateral microcoria (pinpoint, non reactive pupils). Here, we describe an infant diagnosed with Pierson syndrome which also had hypertrophic cardiomyopathy and diffuse cerebral infarctions. The cardiovascular and central nervous system pathology in this case may be a previously unreported component of Pierson syndrome.


The frog represents an important food resource for the people of the city of Man (Cote d'Ivoire). For conservation purposes, frogs often go through a smoking-drying stage before being put on the market. The microbiological tests allowed the detection of the presence of Total Aerobic Mesophilic flora, staphylococci, total coliforms, Escherichia coli as well as Salmonella sp. at respective averages of 4.8.106 CFU/g, 5.105 CFU/g, 1.23.106 1.79.104 CFU/g, 4.97.104 CFU/g. The values obtained are not satisfactory, they exceed the required standards, and this is due to the poor storage conditions, and the lack of hygiene of the traders. The water content was determined by the method of A.O.A.C (2008), the content of total carbohydrates and lipids were determined respectively by the method of Munsen and Walker [1], and by the method of Folch, Lees and Stanley (1957). The average water content of the analyzed samples is 5.5%, the lipid content is 6.66 g/100 g and the carbohydrates are in trace amounts. Minerals were determined by x-ray fluorescence spectrometer. The results reveal the presence of Iron, Manganese, Potassium, Zinc, Calcium, and Phosphorus.


The newly designed Partially Premixed Combustion (PPC) concept operating with high octane fuels like gasoline has confirmed the possibility to combine low NOx and soot emissions keeping high indicated efficiencies, while offering a control over combustion profile and phasing through the injection settings. The potential of this PPC concept regarding pollutant control was experimentally evaluated using a commercial gasoline with Research Octane Number (RON) of 95 in a newly-designed 2-stroke poppet valves automotive compression ignition (CI) engine. Previous experimental results confirmed how the wide control of the cylinder gas temperature provided by the air management settings brings the possibility to achieve stable gasoline PPC combustion at low and medium speed conditions (1250-2000 rpm) for the whole load range (3.1-10.4 bar IMEP) with good combustion stability (CoV (IMEP) below 3%), high combustion efficiency (over 97%), and low NOx/soot levels. In this context, present research focuses on the two main specific drawbacks of this concept. Firstly, the high BSFC resulting from the work required by the mechanical supercharger to sustain the needs in air management since the turbocharging system is not sufficient at low speeds. Secondly the high level of noise generated by the combustion process is known as a matter regarding customers' expectations, especially at high loads. Therefore, a dedicated analysis has been carried out to fully exploit the benefits of the gasoline PPC concept combined with the innovative 2-stroke engine architecture with the aim of identify and break the most relevant trade-offs.


Background: Global or regional evidence showed maternal height as a strong predictor of child survival. However, there is limited information that confirms the intergenerational effect of short maternal height on the risk of offspring mortality in Bangladesh. Therefore, this study aimed to examine the association of maternal height with neonatal morbidity and outcome.Methods: In this analysis authors took data of 100 women who delivered in Kempegowda Hospital in the year 2018 including anthropometry of the mother at admission, anthropometry of the newborn, NICU admissions. Neonatal outcome was assessed by birth weight, anthropometry and NICU admissions against maternal stature which was stratified into 4 groups.Results: Comparison of mean birth weight, head circumference and length showed significant relation with maternal height (p<0.001).Conclusions: Findings should draw the attention of the programme and policymakers to focus on improving maternal nutrition for better offspring nutrition, health and survival.


The past three years of support by the Heavy Elements Chemistry Program have been highly productive in terms of advanced degrees awarded, currently supported graduate students, peer-reviewed publications, and presentations made at universities, national laboratories, and at international conferences. Ph.D. degrees were granted to Shuao Wang and Juan Diwu, who both went on to post-doctoral appointments at the Glenn T. Seaborg Center at Lawrence Berkeley National Laboratory with Jeff Long and Ken Raymond, respectively. Pius Adelani completed his Ph.D. with me and is now a post-doc with Peter C. Burns. Andrea Alsobrook finished her Ph.D. and is now a post-doc at Savannah River with Dave Hobbs. Anna Nelson completed her Ph.D. and is now a post-doc with Rod Ewing at the University of Michigan. As can be gleaned from this list, students supported by the Heavy Elements Chemistry grant have remained interested in actinide science after leaving my program. This follows in line with previous graduates in this program such as Richard E. Sykora, who did his post-doctoral work at Oak Ridge National Laboratory with R. G. Haire, and Amanda C. Bean, who is a staff scientist at Los Alamos National Laboratory, and Philip M. Almond and Thomas C. Shehee,more » who are both staff scientists at Savannah River National Laboratory, Gengbang Jin who is a staff scientist at Argonne National Lab, and Travis Bray who has been a post-doc at both LBNL and ANL. Clearly this program is serving as a pipe-line for students to enter into careers in the national laboratories. About half of my students depart the DOE complex for academia or industry. My undergraduate researchers also remain active in actinide chemistry after leaving my group. Dan Wells was a productive undergraduate of mine, and went on to pursue a Ph.D. on uranium and neptunium chalcogenides with Jim Ibers at Northwestern. After earning his Ph.D., he went directly into the nuclear industry.« less


An ampule reaction between Mo and PCl5 at 200 °C yielded (PCl4)2[Mo2Cl10], the first ternary compound in Mo–P–Cl system. Single crystal X-ray diffraction gave a triclinic unit cell: a = 6.870(1), b = 8.892(2), c = 9.423(2) A, α = 100.24(2), β = 95.55(2), γ = 96.12(2)° (V = 559.3(2) A3, Z = 1, sp. gr. P1, wR2 = 0.0575 and R1 = 0.0279. The ionic compound is built from edge sharing bioctahedra [Mo2Cl10]2– and two tetrahedra PCl4+. The averaged Mo–Clb distance, 2.503(1) A, is longer than the Mo–Clt distance, 2.33(2) A. The Mo … Mo distance, 3.77 A, indicates the absence of a direct Mo–Mo interaction. Semiempirical and ab initio calculations showed the possibility for [Mo2Cl10]2– to exist with long and short Mo to Mo distances, the letter corresponding to the Mo–Mo bond.

Synthese, Kristallstruktur und Bindungsverhaltnisse von (PCl4)2[Mo2Cl10] – der ersten Verbindung im Mo–P–Cl System

Die erste Verbindung im System Mo–P–Cl, (PCl4)2[Mo2Cl10], wurde durch eine Ampullenreaktion von Mo mit PCl5 bei 200 °C hergestellt. Nach der Rontgenstrukturanalyse kristallisiert (PCl4)2[Mo2Cl10] triklin: Raumgruppe P1, a = 6,870(1), b = 8,892(2), c = 9,423(2) A, α = 100,24(2), β = 95,55(2), γ = 96,12(2)°, V = 559,3(2) A3, Z = 1, wR2 = 0,0575, R1 = 0,0279. Die Struktur besteht aus kantenverknupften [Mo2Cl10]2–-Doppeloktaedern und tetraedrischen PCl4+-Kationen. Die mittlere Mo–Clbr-Bindung (2,503 A) ist deutlich langer als die Mo–Clterm-Bindung (2,33 A). Der Mo … Mo Abstand schliest eine direkte Mo–Mo Bindung aus. Halbempirische und ab initio Berechnungen zeigen, das eine stabile Form von [Mo2Cl10]2– mit kurzem Mo–Mo-Abstand und direkter Mo–Mo-Bindung existieren kann.


to decide the destiny of the religion which alone at that time partook in any degree of a spiritual character. Alas, that the champions of DeuteroIsaiah's ideals lost the day-or seemed to ; they continued, as we have seen, to bear witness through the ages ; but the forces of a rigid exclusiveness were too strong. We do not forget that the world owed to Judaism a monotheistic belief and an ethical code far in advance of anything that mankind had known ; that may never be forgotten. Yet it cannot be denied that in practice the religion centred in a narrow nationalistic outlook, a glorying in an arid legalistic system, and in a calculated


Skyrmion excitations are analyzed in imbalanced bilayer quantum Hall systems based on a microscopic theory. A skymion carries both the spin and pseudospin degrees of freedom. In the presence of the parallel magnetic field, the activation energy increases due to the spin component, while it decreases due to the pseudospoin component by deforming a skyrmion into a bimeron (a pair of merons). We propose an approximate formula for the activation energy in imbalanced systems.


The State flood warning and anticipation tools in France have evolve a lot since the years 2000. This paper first presents an overview of the progress made since then. A description of the existing flood vigilance system (www.vigicrues.gouv.fr) is given, with a focus on two of the main on-going improvements: the particular case of river sections under sea influence and the specific organization dedicated to some of the French overseas territories. The next step is to underline the most recent developments carried out to extend the services offered to the public: better communication on occurring floods, forecasts and uncertainties; anticipation of flooded areas; enhanced flash flood warnings dedicated to municipalities; experiments and advice to local authorities on more direct on-site warning systems. The targeted objective is to develop tools and methods to deliver more relevant information, as responsive as possible to the different types of flooding which people are exposed to, over the whole French territory.


The analysis of fire danger at Central Heating and Power Plants (CHPP), as important objects of the Russian Federation energy complex, has been carried out. The statistics of fires at CHPPs is given. The results of experimental research of temperature fields and concentrations of carbon monoxide in small-scale tight experimental installation during the combustion process of power cables covers by rated voltage to 1 KV are presented. The comparison of calculated values of carbon oxide to experimental data has been carried out. Ways of increasing the reliability of experimental definition of substances and materials toxicity indicator by constructing the essentially new experimental stand and also by creating a technique of defining the evolving toxic combustion products from modern construction materials are offered.


CONTENTS: HIGHWAY RESEARCH AND THE ROAD ECONOMY PLANNING PROCEDURES GOVERNMENT LONG-TERM ECONOMIC POLICY SECTOR ACCOUNTS SECTOR ANALYSIS OBJECTIVES FOR THE TRANSPORTATION SECTOR MODEL DECISIONS AND PLANS OF ACTION MEANS AND EFFECTUATION TRAINING, RECRUITMENT.


Leadership Development for the Formal Nurse Leader by Lori Neu, MSN, RN MS, Walden University, 2012 BS, Oklahoma Baptist University, 2001 Project Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Nursing Practice Walden University August 2017 Abstract Nurse leaders are essential to the advancement of healthcare because of their ability to bridge the gap of knowledge between clinical practice and the business of healthcare. Developing nurse managers is imperative to the future of nursing given their influential role in healthcare. The central topic of exploration in the project was how nurse managers use the American Organization of Nurse Executives (AONE) NurseNurse leaders are essential to the advancement of healthcare because of their ability to bridge the gap of knowledge between clinical practice and the business of healthcare. Developing nurse managers is imperative to the future of nursing given their influential role in healthcare. The central topic of exploration in the project was how nurse managers use the American Organization of Nurse Executives (AONE) Nurse Manger Inventory Tool to assess their management skills after exposure to the leadership development program currently available to them. In this project, the novice to expert theory was used to evaluate the existing leadership development program at a tertiary care academic medical center with Magnet accreditation within the Midwest. Secondary data from the AONE Nurse Manager Inventory was analyzed with focus on three professional domains: the art, science and leader within. The analysis was used to identify the current program's strengths and weaknesses, and make recommendations to increase education for nurse managers in the science domain; specifically in the subcategories of financial and strategic management. Enhanced educational opportunities in financial and strategic management will support the progression of nurse managers' development along the continuum of novice to expert. The implications for social change from this project exist through the creation of new leadership outcome measures supporting Magnet redesignation for this facility and as an example to other organization on their journey of meeting Magnet requirements in nursing leadership development. Leadership Development for the Formal Nurse Leader by Lori Neu, MSN, RN MS, Walden University, 2012 BS, Oklahoma Baptist University, 2001 Project Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Nursing Practice Walden University August 2017 Dedication This project is dedicated to all of the hardworking nurse leaders that can't find time to develop themselves. Developing oneself will enable you to be a stronger leader through which you will learn how to strengthen your staff. The strong leadership of one dedicated nurse manager can enable many nurses to optimally care for the patients under your watch. Acknowledgments First and foremost I want to thank my husband, Tony, for his loving support of me through this process. He is the support that has made this accomplishment possible, from encouraging me to take this next step in my journey to the 'extra's' that he does every day and with our kids. Thank you to my children for understanding the extensive amount of time and work this has taken me, all the while showing me how to have fun through this journey. You three truly are my strength and support beyond words, my forever loves. My parents have been a constant support over all my years encouraging me to continue to reach higher especially through the difficult moments the last few years. Thank you can never express enough gratitude. The grace of God had been displayed to me time and time again through the support of family, friends and my faith to find the perseverance to continue. To my mentor, without you and your continued support, friendship, and offering of a multitude of opportunities I would not have considered nor been able to complete this amazing learning journey. Thank you for your patience and encouragement, you have been a strength and support I couldn't have asked for a better mentor. Dr. Taylor, thank you for your consistent support in my writing and class work the past too many years, encouraging and challenging me to go farther and make this end product what it is today. Thank you for also encouraging me to take it all in stride and to keep working hard, we will get there.


The Balkans, which deterritorialized from the Ottoman geography to a great extend as of
second constitutional period, taken up in Turkish literature with various aspects. The Balkan societies, one
of the basic issues in the Second Constitutional Period press, were paid closer attention by the Ottoman
intellectuals due o the emigrations to Istanbul. The fact that the Balkans deterritorialized from the
Ottoman territory paved the way for number of poets and authors, especially the ones popular in the
region, to write on the geography. This geography sustained its existence as a basic theme in Republican
period literature.
The Balkans, proclaimed their independence following the collapse of Yugoslavia, became a
centre of focus for the Turkish intellects once again. However, this time the interest shown is lesser than
those after the war of the Balkans. The Bosnian war became an effect to increase the gradually declining
interest; various poets-writers carried the tragedies in the war to their poems-writings.
In this study, focusing on the Bosnian war, consideration of Bosnia in New Turkish poetry will
be examined in the context of war-literature relationship.


In the Disk Diffusion Antibiotic Sensitivity test (The Kirby-Bauer test) a thin film of bacteria applied on a plate is subjected to various antibiotics. The Zone of inhibition is a circular area around the spot of the antibiotic in which the bacteria colonies do not grow. The zone of inhibition can be used to measure the susceptibility of the bacteria to wards the antibiotic. The process of measuring the diameter of this Zone of Inhibition can be automated using Image processing. In this work an algorithm is developed, using Computer Vision, which will detect the zones of inhibition of the bacteria. This work demonstrates an effective approach of measuring the Zone of Inhibition by calculating the radius of the zone by drawing contours and setting the right value of threshold. This work also determines if a particular bacteria is susceptible or resistant to the applied antibiotic using the calculated Zone of Inhibition and the prescribed standard values.


A radio frequency identification (RFID) system consists of a reader, a writer, and a tag. Filmtype half-wavelength dipole antennas (shown in Fig. 1.1) have been used as tag antennas in many applications [1]. The antenna performance is governed by the electric current in the tag. When the abovementioned antenna is mounted on the surface of a metallic object, the radiation characteristics are seriously degraded because of the image current induced in the object. Therefore, studies have been carried out to construct tag antennas that are suitable for use with metallic objects, and some promising antenna types have been proposed. In this chapter, design approaches for metal-proximity antennas (antennas placed in close proximity to a metal plate) are discussed. In Section 2, typical metal-proximity antennas are described. An example of the aforementioned type of antenna is a normal-mode helical antenna (NMHA), which can show high efficiency despite its small size. We focus on the design of this antenna. In Section 3, the fundamental equations used in the NMHA design are summarized. In particular, we propose an important equation for determining the selfresonant structure of the antenna. We fabricate an antenna to show that its electrical characteristics are realistic. In Section 4, we explain the impedance-matching method necessary for the NMHA and provide a detailed description of the tap feed. In Section 5, we discuss the use of NMHA as a tag antenna and provide the read ranges achieved.


Asparagus is a kind of rare vegetable with strong health function.In this paper,the processing and treatment of asparagus,the raising of culture,t he selection of stabilizer and subsidiary material,and the ascertainin g of technique condition were investigated.Finally,health mixing yoghurt with bright green color and asparagus smell were prepared,which suit to middle -aged and old consumers'needs.


In this article, we propose a control law for almost-global asymptotic tracking (AGAT) of a smooth reference trajectory for a fully actuated simple mechanical system (SMS) evolving on a Riemannian manifold which can be embedded in a Euclidean space. The existing results on tracking for an SMS are either local, or almost-global, only in the case the manifold is a Lie group. In the latter case, the notion of a configuration error is naturally defined by the group operation and facilitates a global analysis. However, such a notion is not intrinsic to a Riemannian manifold. In this paper, we define a configuration error followed by error dynamics on a Riemannian manifold, and then prove AGAT. The results are demonstrated for a spherical pendulum which is an SMS on $S^2$ and for a particle moving on a Lissajous curve in $\mathbb{R}^3$.


The utility model discloses a multi-core industrial circuit control cable containing power lines, which comprises power lines and signal lines; each power line comprises a first conductor, a first insulating layer and a first shielding layer, the first insulating layer is extruded on the first conductor to form a core lead, and a pair of power line pairs is formed by two core leads by means of pairwise twist and then the outer part thereof is lapped with the first shielding layer; and each signal line comprises a second conductor, a second insulating layer and a second shielding layer, the second insulating layer is extruded on the second conductor to form a core lead, and a pair of signal line pairs is formed by core leads by means of pairwise twist and the outer part thereof is lapped with the second shielding layer; the power line pairs lapped with the first shielding layer and the signal line pairs lapped with the second shielding layer are stranded into a cable and then the outer part thereof is extruded with a total braid layer and a sheath to form the control cable, and a grounding wire is disposed between the first shielding layer, the second shielding layer and the total braid layer. The utility model combines the power lines and the signal lines into the same control cable, thereby improving the control capability of the industrial circuit, and facilitating the replacement between simple equipment.


1. The Crisis, the Study, and the Book 2. The Purposes of Doctoral Education 3. Admissions, Recruitment, and Enrollment 4. Paying for Doctoral Education 5. Student Satisfaction with their Programs: Curriculum, Teaching, Mentoring, and Supports 6. The Dissertation 7. Preparing Students for the Job Market 8. Outcomes in Doctoral Education 9. Conclusions, Implications, and Challenges for the Future References Index