Within this sector, women work across all aspects of writing, direction, production, editing and design, yet the dominant narrative continues to construe 'maverick' white male auteurs such as Quentin Tarantino or Wes Anderson as the face of ...


This paper explores the possibility of applying distributed artiicial intelligent systems and multi-agent systems to help in the design of engineering software systems. We deene an environment consisted basically by artiicial designers that based on their knowledge, help a human designer to obtain the design of the software systems. The software design engineering problem we take as example is the design of the interlocking software for distributed track-vehicle controllers. The design of these modules are based on Petri nets, from which we can derive invariants that are used as the basis to characterize agent's knowledge in our design aid environment.


Autism spectrum disorder (ASD) refers to a syndrome of social deficits and repetitive behaviors. It remains a behaviorally defined syndrome with no reliable biomarkers. Although many studies have been devoted to detecting clinically useful biomarkers based on resting-state functional magnetic resonance imaging (rs-fMRI), they fail to take the strong group relationships in the feature selection process, thus leading to significant information loss. To address this issue, we propose an automatic method for ASD diagnosis based on elastic net with rs-fMRI data. The advantage of the elastic network method is that it does not need to make feature selection in advance, which greatly saves time and improves the efficiency of the algorithm. Experimental results on the public database ABIDE demonstrate the effectiveness and usefulness of the proposed method.


Entrepreneurial orientation EO is a practice that provides basic results and entrepreneurial action. Therefore, this study aims to explain the development of entrepreneurship orientation (EO) and its measurement based on previous research using a qualitative approach with literature research methods (library research). Finding that EO is an entrepreneurial model focused on management strategies and also used to measure EO is Proactive, Innovative, risk-taking, Competitiveness, Autonomy, Competitive Energy.

Keywords: Entrepreneurial Orientation, Entrepreneurship, Entrepreneurial Orientation Measurement


For a large number of E-mails, the classification is an effective management method. In the process of improving process efficiency and filtering junk mail, the extraction of E-mail characteristic is the key problem of exactness classification. In order to make the classification has a more distinct division characteristic words, Inverse document frequency is used. The extracted characteristic words are used to classifying mails, and the classification results are judged correct or erroneous by users. By classifying and feedback process E-mail classification rules are automatic generated and adjusted to adapt the users. The experiment results indicate the method is availability.


The principles of Mossbauer spectroscopy and the hyperfine interaction parameters evaluated from Mossbauer spectra are summarized and discussed from the viewpoint of materials research. A study on iron impurity in aluminum has been described as a typical application of the 57 Fe Mossbauer spectroscopy in materials science.


FOCUS, the "Fast Object-Oriented C + + Ultrasound Simulator" (http://www.egr.msu.edu/~fultras-web), simulates nonlinear ultrasound propagation by numerically evaluating the Khokhlov–Zabolotskaya–Kuznetsov (KZK) equation. For continuous-wave excitations, KZK simulations in FOCUS previously required that the simulations extend over large radial distances relative to the aperture radius, which reduced the effect of reflections from the boundary on the main beam. To reduce the size of the grid required for these calculations, a perfectly matched layer (PML) was recently added to the KZK simulation routines in FOCUS. Simulations of the linear pressure fields generated by a spherically focused transducer with an aperture radius of 1.5 cm and a radius of curvature of 6cm are evaluated for a peak surface pressure of 0.5 MPa and a 1 MHz fundamental frequency. Results of linear KZK simulations with and without the PML are compared to an analytical solution of the linear KZK equation on-axis, and the results show th...


Abridged version Gleditsia triacanthos (Leguminosae, Caesalpinoideae), a polygamous tree which has become well acclimatized in Southern Europe, can be used as supplementary winter ovine fodder because its long pods have a high sugar and protein content (Detwiler, 1947; Putod, 1982). This woody plant, which is resistant to urban pollution, is also used as an ornamental and landscape tree (var. inermis). It was not possible to multiply this species using the conventional cloning methods whereby cuttings are made from selected adult plants. As in many trees, the cuttings are no longer able to root when the plant has become sexually mature. Since we are still awaiting the results of studies on appropriate treatments (Alskieff, 1977; Franclet, 1979; Ballester et al., 1980; Navarro, 1980; Huang et al., 1992 (Arnaud et al., 1993), we had to rely meanwhile on in vitro propagation of seedlings of a few weeks old obtained under axenic conditions (Basbaa et al., 1993). Four successive generations were produced. With...


Until now, it is unclear what the economic system adopted by Indonesian nation. Perhaps people say economic system Indonesia is a mix between the capitalist economic system and the Socialist-Liberal-Command. Whatever the Indonesian economic system adopted, a clear until now the Indonesian economy increasingly lagging behind countries - countries ASEAN others who used it under Indonesia. Indonesia's economy is still not in favor of interest people. The little people are likely still not optimal in enjoy the fruits of national development, resulting in a gap that is very width between the rich and the poor. Since the State of Indonesia's independence, actually Bung Hatta launched a cooperative economic system for the Indonesian nation. Even This cooperative economic system has been set forth in the Constitution 'of 1945, in particular Article 33. But in reality, the government (nation) Indonesia never consistent with Article 33 is in the running wheel the national economy. Perhaps this is what causes the economy Indonesia continues to face chronic problems such as those in on. If the economic system is fundamentally cooperative studied, actually cooperative has characteristics that are closely aligned with the situation and culture Indonesian nation. Therefore, it is not something that is not possible if the cooperative economic system serve as a solution to Indonesia's economic problems. The issue is whether the government and the Indonesian people can apply cooperative economic system This consequently and continue.Keywords :  Cooperative Economic System, Indonesia Economy


The research analyzes the translation strategies of idiomatic expressions found in a marketing monograph entitled Marketing 4.0: Moving from Traditional to Digital and Marketing 4.0: Bergerak Dari Tradisional ke Digital. This study aims to identify the use of translation strategies and the most used strategy to translate idiomatic expressions in those monographs. The theory applied in this study is from Mona Baker (2018). The results of this study revealed that the translation strategies found are using an idiom of similar meaning and form (SMF), using an idiom of similar meaning but dissimilar form (SMDF), translation by paraphrase, and translation by the omission of a play on idiom. Moreover, the most frequently used strategy found is the paraphrasing strategy (69.23%). The results of this study are expected to provide a better understanding of translation strategies for idiomatic expressions to the readers.


PT Semen Padang was the oldest cement industry in Indonesia located in Indarung, Padang City, West Sumatra. To protect the safety and health of workers, PT Semen Padang conducts an Occupational Health and Safety (OHS) Management System by controlling the Recordable Incident Rate (RIR) number. PT Semen Padang used Minister of Manpower Regulation No. 03 / Men / 1998 to calculate RIR numbers because it has more than 500 workers. The number of RIRs obtained from 2013-2017 experienced fluctuations. The highest RIR rate was 2.50 in 2016 and was above the target of PT Semen Padang, which amounted to 2.0. In suppressing the RIR figures, PT Semen Padang implemented an activity plan, in the form of inspection, socialization and information of OHS. Viewed from 2013-2017 the magnitude of the implementation of the activity plan had a significant effect on the decrease in the RIR rate in PT Semen Padang (p <0.05). The solution for RIR activity plan improvement can be in the form of increasing the frequency of inspections carried out in locations with high risk of accidents, socialization of OHS based on the type of dominant occupational accidents and proper placement of OHS information in the work area.


This paper introduces a new control strategy for heterogeneous multi-robots systems dedicated to industrial logistic setups. This control strategy is based on both distributed intelligence and machine learning and involves three parts: the rigid formation controller, the perception system and the path planner. Our controller is event-based and thus its control-coordination strategy can be self-adaptive and applied to real dynamic environment. During the navigating process, the multi-robots system derives the environment model, performs the path planning process that guaranties both the transportation constraints and the obstacle avoidance. For the validation, both simulation and real robot experiments are performed. The results show that the developed control strategy can be well used for realistic logistics applications.


Introduction

The exploration of Callisto is part of the extensive interest in the icy moons characterization. As other missions will focus on Ganymede and Europa, mission proposals devoted to the exploration and characterization of Callisto are currently emerging [2][6]. Compared to the other Galilean moons, the outermost moon has kept the best-preserved records of the Jovian system formation, which makes it a candidate of choice to understand how the Jupiter system formed, and how it works.

Led by the National Space Science Center (NSSC), Chinese Academy of Science (CAS), the Gan De mission [2] aims to send an orbiter around Callisto in order to map its gravity and magnetic field, and to characterize its exosphere, surface and interior. Callisto’s degree of differentiation will also be investigated as well as the possible existence of an internal ocean, as Galileo measurements suggested.

Because the mission is at a very early planning stage, there is no definitive mission plan yet. In this context, we selected a small representative set of potential science orbits around Callisto. These orbits are tested under different assumptions in a detailed simulation environment, to analyse the orbit recovery as well as the recovery of Callisto gravity field and k2 Love number using tracking data. The effect of non-gravitational forces exerting on the orbiter is carefully considered, especially the strategy to handle them through the whole estimation process.

Exploring different orbits

Flybys of Callisto from the JUICE and the Europa Clipper missions will already provide further information on this moon [4]. However, the global mapping of the outermost Galilean moon will be uniquely improved by means of an orbiter at a high inclination and a low altitude. A specific difficulty in the orbit design in the Jovian system is related to the orbit stability, which is highly impacted by the influence of Jupiter as a third body exerting strong perturbations on a Callisto orbiter.

Additionally, the occultations of the Sun by Callisto should be minimized to ensure a maximum solar illumination for power, which is critical this far from the Sun. This implies a minimum angle between the orbital plane w.r.t the direction of the Sun (βSun), which is larger the lower the orbit is. Depending on the position of the Earth at that time, this might have a direct impact on the angle between the orbital plane w.r.t the direction of the Earth (βEarth), which is of importance for orbit determination and gravity field recovery using Doppler tracking data.

In this presentation, we selected various low Callisto orbits, which are suitable as science orbits for Gan De. These orbits have different altitudes, Earth beta angles, and injection date into orbit. Although several of them can be used sequentially, they are considered separately.

A detailed force model

The set of different reference orbits is propagated using the planetary extension of the Bernese Software (BSW) [3]. All the planets of the solar system, as well as the Galilean satellites, are considered as point masses. In the case of Jupiter, the zonal harmonics of the gravity field are also part of the force model. Because our knowledge of Callisto’s gravity field is restricted to the results of the Galileo mission (degree 2) [1], we have derived a synthetic gravity field as ground truth for our simulation. The scaled gravity field of the Earth’s Moon is used from degree 3 to 100. An artificial value of k2 Love number is also adopted to provide a ground truth.

In order to rely on solar power this far from the Sun, the size of the solar panels is significant, which makes the effect of the solar and planetary radiation pressure on them essential to account for. However, the modelling of these forces can be challenging, particularly because of their dependency on the geometry and the optical properties of the probe. Even with a precise macro model, the optical properties of each plate can evolve with time. Several strategies are tested to handle these non-conservative forces, such as the use of pseudo-stochastics parameters and the possibility of an on-board accelerometer.

Orbit determination and gravity field recovery

Using a detailed noise model [5] and a realistic tracking station schedule, realistic Doppler tracking data (2-way Ka-band Doppler range rate) is simulated as measurements from the Deep Space Network. The non-gravitational accelerations in action during the orbit propagation are used to generate realistic accelerometer measurements. These observations are then used to reconstruct the orbit along with dynamical parameters in a global least-squares adjustment.

Within this closed-loop simulation, we investigate the impact of the non-gravitational accelerations and orbit geometry on the orbit determination and the recovery of the geodetic parameters. The focus of this presentation is on the quality of the retrieved gravity field parameters and tidal Love number k2.

Acknowledgements

This study has been funded with the support of the Swiss National Foundation (SNF).

References

[1] Anderson, J. D., et al. "Shape, mean radius, gravity field, and interior structure of Callisto." Icarus 153.1 (2001): 157-161.

[2] Blanc, Michel, et al. "Gan De: Science Objectives and Mission Scenarios for China's Mission to the Jupiter System." EGU General Assembly Conference Abstracts. 2020.

[3] Dach, R. et al. "Bernese GNSS software version 5.2." (2015).

[4] Di Benedetto, Mauro, et al. "Analysis of 3GM Callisto Gravity Experiment of the JUICE Mission." arXiv preprint arXiv:2101.03401 (2021).

[5] Iess, Luciano, et al. "Astra: Interdisciplinary study on enhancement of the end-to-end accuracy for spacecraft tracking techniques." Acta Astronautica 94.2 (2014): 699-707.

[6] Smith, David E., et al. "MAGIC, A Discovery Proposal to the Icy Moon Callisto." AGU Fall Meeting Abstracts. Vol. 2019. 2019.


The preparation of α,α,β-trisubstituted β-lactones has opened the route to living anionic ring-opening polymerization of these monomers. Therefore, transfer reactions due to hydrogen abstraction were limited and it is now possible to strickly control sample molecular weight. Moreover, living end-groups lead to the preparation of block co-polymers with block controlled lenghts. In the same way, high-molecular-weight statistical co-polymers have been synthesized. Hydrolyzable micelles and nanoparticles will be prepared from these co-polymers after chemical modifications to adjust the hydrophilic/hydrophobic balance.


Chronic myeloproliferative disorders (CMPD) include hemoblastoses with abnormal proliferation of myeloid lineages and concomitant alterations in the peripheral blood indicators. The aim of this study was to assess the frequency and structure of ophthalmic complications as a quality of life factor in patients with CMPD. A group of patients with hemoblastoses of this type (n = 41) were surveyed using National Eye Institute Visual Function Questionnaire-25 along with a comprehensive examination by noninvasive ophthalmological techniques. The patients typically reported impaired visual acuity, visual discomfort and foreign body sensation in the eyes. Though many of the patients assessed their general health and vision as satisfactory, the vast majority (68.3%) expressed serious concerns about their visual abilities. The ophthalmological examination revealed various defects including refractive errors (61%), corkscrew dilation and tortuosity of conjunctival and retinal vessels (77.9%), recurrent subconjunctival hemorrhages (39%) and dilated optic nerve sheaths (36.6%). The survey data indicate that visual impairments significantly affect quality of life in patients with CMPD. Overall, the results underscore the importance of interdisciplinary approach in the management of patients with CMPD to enable early diagnosis and feasible correction of the ophthalmic component.


C17H11ClFNO5, monoclinic, P121/c1 (no. 14), a = 7.489(5) Å, b = 18.367(5) Å, c = 11.752(5) Å, 0 = 94.222(5)°, V = 1612.1 Å, Z = 4, Rgt(F) = 0.032, wRref(F) = 0.083, T = 293 K. Source of material The mixture of potassium carbonate (5.75 mmol), methyl chloroacetate (5.75mmol), the acetic acid and propanoic acid derivatives of 6-(2-fluorobenzoyl)-5-chloro-2-benzoxazolinone (5 mmol; 1:1, v/v) in 30 mL acetone were heated to reflux and stirred for 4 h. 100 g Icewaterwas added to the cooled (273-283K) reaction mixture. After stirring for 1 h, the precipitate was collected by filtration, washed with water, dried, and recrystallized from ethanol (yield 81 %, m.p. 383-385K). IR data are available in the CIF. Discussion Benzothiazolinone/2-benzoxazolinone derivatives exhibit a variety of pharmacological effects, including analgesic and antiinflammatory activity [1]. In the title compound the F1—C2 distance 1.350(2)Å is in agreement with that for ethyl[6-(2-fluorobenzoyl)-2-oxo-benzothiazolin-3-yl]-butanoate [2] (1.346(3) Å). The bond distance of N1—C14 is 1.365(2)Å and the double-bond length forC14.O3 is 1.199(2) Å. These values are also comparable to those of 1.343(2)Å and 1.204(2)Å observed in a related structure [3].The Cl1—C9 bond distance is 1.742(2) Å and the C16–O5–C17 and F1–C2–C1 bond angles are 116.9(2)° and 119.6(1)°, respectively. The C17–O5–C16–C15 and C13–C8–C9–Cl1 torsion angles are 179.0(2)° and 176.9(1)°, respectively. According to our CNDO calculations [4], the dipole moment of title molecule is about 6.77 D. The HOMO and LUMO energy levels are –9.0565 eV and –0.7091 eV, respectively. The crystal structure is stabilized by the three-dimensional C–H···O type short hydrogen contacts. Z. Kristallogr. NCS 221 (2006) 541-542 / DOI 10.1524/ncrs.2006.0190 541 © by OldenbourgWissenschaftsverlag,München Crystal: colorless prism, size 0.33 × 0.42 × 0.52 mm Wavelength: Mo K/ radiation (0.71069 Å) %: 2.76 cm−1 Diffractometer, scan mode: Stoe IPDS II, * 2'max: 55.58° N(hkl)measured, N(hkl)unique: 14093, 3686 Criterion for Iobs, N(hkl)gt: Iobs > 2 ((Iobs), 2649 N(param)refined: 227 Programs: SIR97 [5], SHELXL-97 [6], ORTEP-3 [7],WinGX [8] Table 1. Data collection and handling. H(3) 4e 1.2124 0.0411 0.3970 0.074 H(4) 4e 1.1438 0.1315 0.5231 0.084 H(5) 4e 0.8516 0.1663 0.5380 0.086 H(6) 4e 0.6265 0.1127 0.4246 0.075 H(10) 4e 0.7769 −0.0358 −0.0935 0.059 H(13) 4e 0.5124 −0.1203 0.2320 0.062 H(15A) 4e 0.7084 −0.1347 −0.2454 0.071 H(15B) 4e 0.6065 −0.2089 −0.2646 0.071 H(17A) 4e 1.0684 −0.3060 −0.3990 0.141 H(17B) 4e 1.0705 −0.3295 −0.2706 0.141 H(17C) 4e 1.1631 −0.2567 −0.3038 0.141 Table 2. Atomic coordinates and displacement parameters (in Å). Atom Site x y z Uiso


AIM To investigate whether tubeimosides induce apoptosis in CNE-2Z. METHODS Growth inhibition by tubeimosides was measured using MTT assay. The effect of tubeimosides on apoptosis induction of CNE-2Z cell line was studied by the fluorescent microscopy, electronic microscopy, DNA agarose gel electrophoresis, flow cytometry analysis. Western blotting was performed for detecting the apoptosis-related gene. RESULTS The growth of CNE-2Z cells was inhibited obviously by tubeimosides. CNE-2Z cells showed typical apoptotic features observed by fluorescent microscopy, electronic microscopy. DNA fragmentation into multiples of low molecular weight DNA(180~200 bp) was detected by agarose gel electrophoresis of DNA; Sub-G 1 peak was found by flow cytometry analysis, and the apoptosis index was 58 0%. The expression of bcl-2, inhibitor of apoptosis, decreased apparently; while that of bax, inducer of apoptosis, increased notably at 1, 3, 5 h after the addition of tubeimosides. The cleavage of caspase-3 was noticed at 1, 3, 5 h after the treatment of tubeimosides. CONCLUSION Tubeimosides could induce the apoptosis of CNE-2Z cells. The induction of apoptotic by tubeimosides was closely associated with bcl-2, bax and caspase-3.


Tan Yiuxue is a famous scholar in study of the Tang literature. His Study of Chronological Life of the Tang Poets is an important monograph the Tang poets in the 20th century, and Tan Yiuxue fills in gaps in study of the Tang Literature with the scientific research method by it. Tan is an essay writer with strong cultural awareness, personality and humorous style still.


Scott Bearer holds a B.S. in forestry and wildlife from Virginia Tech (1997), an M.S. in ecology from Clarion University (1999), and a Ph.D. in landscape ecology from Michigan State University (2005). Scott also completed a postdoctoral appointment with the U.S. Fish and Wildlife Service in 2006, when he began working for the Nature Conservancy as a forest ecologist and senior conservation scientist.


The total graph T (ΓN (Zn)) of Zn with respect to its nil ideal N(Zn) = {x ∈ Zn : x ≡ 0(mod n)} is a simple, undirected graph with vertex set Zn and any two distinct vertices x and y of T (ΓN (Zn)) are adjacent if and only if x + y ∈ N(Zn). In this paper, we introduce a new graph structure called a Zero forcing graph of T (ΓN (Zn)), denoted by ZF(T (ΓN (Zn))), as a simple, undirected graph in which all the possible zero forcing sets of minimum cardinality of T (ΓN (Zn)) are taken as vertices and any two distinct vertices S1 and S1 of this graph are adjacent if and only if S1 ∪ S2 = Zn.


Trafficking in women for prostitution remains a modern form of slavery. Paradoxically, governments and legal systems tend to target the victims (trafficked women) instead of the criminal traffickers. The present study attempted to investigate the roots of such a lenient social response. Following a consensus perspective, it was first hypothesized that this offense was considered by the public to be a relatively nonserious offense because it involved prostitutes, and second, as in other cases of male violence against women, it was hypothesized that the public views toward this offense were affected by traditional gender-role attitudes toward women. To this end, respondents from a national sample were asked to evaluate hypothetical short crime scenarios representing cases of trafficking in women and other offenses. The findings indicate that the public perceives such criminal acts as serious, both for egalitarian and traditional respondents. This finding challenges the consensual basis of the lenient approach toward traffickers in women. The implications of the findings are discussed.


This chapter argues that austere times presented opportunities to reassess strategic concepts, think rigorously about goals, recalibrate priorities, and link means and ends. Constraints on defense spending forced policymakers to think more creatively about diplomatic solutions. This sometimes catalyzed bold initiatives to reassure friends and engage adversaries. In the past, budgetary austerity also forced officials to wrestle more forthrightly with the trade-offs between priorities at home and commitments abroad. It was an exercise that invariably reminded all Americans that the real sources of U.S. strength in the world were the health of its domestic economy, the vitality of its people, and the resilience of its political institutions.


Introduction Resistance is a complex, multifaceted phenomenon that has been widely discussed in management literature, and more often than not, change scholars have identified employee resistance as a crucial factor that influences the success of change implementation. For the last several decades change research has focused on ways to reduce or eliminate resistance, with the primary assumption that it is dysfunctional and therefore thwarts change implementation (Lewis, 2011). Most of this work has been done in the Western context, with several researchers pointing towards the dearth of change management and change resistance studies in the Indian context (Bhatnagar, Budhwar, Srivastava & Saini, 2010). Bezboruah (2008) called for a need to understand employee resistance in India. The concept of resistance was first introduced by Lewin (1947), and since then, it has been defined as a multifaceted phenomenon that leads to unanticipated delays, costs and instabilities in implementing change (Ansoff, 1988); behavior that attempts to maintain the status quo when the organization wants to change the status quo (Zaltman& Duncan, 1977); willingness to engage in deception (Shapiro, Lewicki& Devine, 1985); or as a reactive process that signals power relations and organizational members opposition to initiatives taken by other members (Jermier, Knights & Nord, 1994). Needless to say, most of the times resistance has been described in negative terms--it either prevents organizations from carrying out change implementation or creates challenges that make this process more difficult. Resistance research can be broadly divided into two approaches: the first which provides a more conventional, traditional view of resistance recognizes it as a barrier to change processes and studies it primarily from the change-agent's perspective. Researchers taking a contemporary view of resistance question the traditional 'change agent centric' perspective of change implementation and argue for greater focus on employee perspective. Researchers have begun to believe that resistance can provide valuable insights from employees and raise legitimate concerns about the change process itself. However, both these views have primarily been shaped based on Western concepts of change as well as resistance. Unfortunately, studies examining Indian perspectives regarding resistance are few and far in between. This article attempts to close this gap by taking a contemporary view of resistance by examining it from the employee perspective, and doing so in the Indian context. Since resistance has been considered problematic for change implementation, most studies focus on attempts to 'manage' resistance. In an effort to understand (and prevent) resistance, significant body of resistance research has focused on identifying reasons that lead to resistance and thereby managing resistance. Factors Leading to Resistance Schein (1993) found change resistance to be a ubiquitous phenomenon in organizations. Researchers have identified a wide variety of factors that provide explanation for resistance: organizational culture, organizational politics, lack of resources, lack of commitment, insufficient information, poor timing, lack of trust, uncertainty, fear of unpleasant consequences (Dent & Goldberg, 1999; Labianca, Gray & Brass, 2000), psychological support, gradual and flexible participation of change (Fernandez & Rainey, 2006), loss of status or power, lack of reward, disruption of routine (Gilley, Godak& Gilley, 2009). With the emergence of such wide variety of factors, some researchers attempted to classify them in to broad categories. Largely, literature suggests that resistance can be because of individual or organizational factors, though focus seems to be more on individual reasons for resisting change. This focus is not surprising because change researchers have acknowledged that it is not possible to change organizations in meaningful ways unless the employees change (Poole & Van de Van, 2004). …


Recently, we have shown the existence of a finite energy one-half monopole. In this paper, we would like to introduce electric charge into the one-half monopole configuration, thus creating a one-half dyon. This one-half dyon possesses finite energy, a magnetic dipole moment and angular momentum. Hence it is able to rotate in the presence of an external magnetic field. Similarly to single pole dyons and MAP dyons, this one-half dyon possesses a critical (maximum) electric charge, total energy and magnetic dipole moment when the Higgs self-coupling constant is non-vanishing and the electric charge parameter approaches one. This one-half dyon solution does not satisfy the first order Bogomol'nyi equations and is a non-BPS solution in the limit of a vanishing Higgs self-coupling constant.


In this article we discussed a method to discretize multivariate time series using the recurrent neural network (RNN). Time series discretization is a technique to convert real-number time series into an array of discrete elements, which is essential for downstream applications where a finite number of inputs is required such as sequence prediction and classification. While there had existed several sophisticated algorithms to compute discretization, we looked at RNN to investigate the potential of the architecture in solving this problem. We employed Long Short-Term Memory (LSTM) network which had the ability to memorize the information and carry it over an arbitrary range of time steps by introducing cell states in the recursion. This made the final cell state a plausible representation of the time series with arbitrary dimensions and decoupled from time. The cell state might serve as an input for subsequent clustering algorithms to generate clusters. The clusters could serve as arbitrary elements and the original time series could be represented as a procession of cluster groups. An outline of the learning procedure was as followed. From a time series of length N, a collection of segments in length t was obtained. The segments were fed to an LSTM RNN to learn to predict the value at $\mathrm{t}+1$. After learning the segments were fed into the network again and the final cell states for each segment were collected. The final cell state acted as a representative vector of the time series. Then k-means clustering was applied to assign each state into a finite number of clusters. The output for time series in length N would be a sequence of categorical elements in length $\mathrm{N}-\mathrm{t}+1$. We would demonstrate this operation on discretizing artificial datasets and evaluate the performance of this methods with two variants.


After put-into-operation of the new 2.4 Mt/a grate rotary-kiln production line in Shagang Iron Steel Groups Corporation,there were a series of problems in operation.Thus,technical improvements to several great production systems have been made,achieving good results in increment of sinter quality output.


Objective
To observe the effect of Chaihu-Longgu-Muli decoction combined flupentixol and melitracen tablets for the post-stroke depression (PSD).

Methods
The random number table method was used to divide the 150 patients with PSD into the observation group and control group, 75 cases in each group. On the basis of conventional treatment of stroke, the control group took oral flupentixol and melitracen tablets, and the treatment group add Chaihu-Longgu-Muli decoction on the basic treatment of control gorup. The treatment of two groups last 1 month. The serum APN concentration was detected before and after treatment. Besides, the HAMD, NIHSS scores, and the clinical curative effect were observed and compared.

Results
The total effective rate of the observation group was 81.3%, and control group was 58.7%, which the difference between the two groups showed the statistical significance (P<0.05). After treatment, the serum APN (7.8 ± 3.7 mg/L vs. 6.1 ± 3.3 mg/L, t=2.970) level in the observation group was significantly higher than that in the control group (P<0.05). The HADM (16.4 ± 3.6 vs. 19.6 ± 4.9, t=4.558), NIHSS (5.0 ± 1.6 vs. 7.7 ± 2.0, t=9.129) scores in the observation group were significantly lower than those in the control group (P<0.01).

Conclusions
The Chaihu-Longgu-Muli decoction combined flupentixol and melitracen tablets can reduce the serum APN level of PSD patients, improve patients with depression, alleviate patients' neurologic deficits.

Key words:
Stroke; Depression; Chaihu-Longgu-Muli decoction; Adiponectin


The efficiency of "conflict-based Clause-Learning Boolean Fulfilment (CDCLSAT)" solvers on engineering problems from several fields has been seeing notable modifications during the last 20 years. Various analyses have proposed SAT-based tactics for cryptanalysis, like finding conflicts in hash capabilities and disassembling symmetrical encryption schemes, as just a result of the availability of efficient broad sense look solvers like SAT Solver. The majority of the currently suggested SAT-based cryptanalysis techniques are Black Box inventions, in which the cryptanalysis problem is encrypted as SAT and illuminated using CDCLSAT Solvers. The method has the issue that now the encoding created in this method may be too extensive for any slashing arrangements to decode successfully. This approach's solution is not manner set up to handle a specific or provided example, which is a further notable drawback. The disadvantage of this technique is that decoding created in this manner may be too extensive for any sophisticated organization to correctly decode. One notable drawback of this strategy that the solution does not way set up to deal with a specific or given scenario. In order to understand these problems, SAT Solutions have provided solutions to two related existing gaps (exhibited in Fast Programme Encrypted 2009) about the presence or absence of these minute secrets. SAT nameservers have provided an effective solution, even though that such problems might appear difficult to address. SAT nameservers have provided a useful plan of action, despite the fact that such problems it might seem difficult to fix and also discuss the experiment that was conducted to see how well an intermediate SAT Solution performed when doing encrypted cryptanalytic tasks that proved to be relatively challenging. Allocation and or before assaults here on MD4 computation are far less similar.


Based upon our previous works, a systematic mathematical demonstration of polycyclic aromatic hydrocarbons (PAH) graphs has been carried out in this laboratory. The uniqueness of characteristic number (linear topology notation of PAH), the even number theorem for the discriminating of complete aromaticity for PAH in structure prediction and enumeration, the transformation theorem from the characteristic number to form the adjacency matrix uniquely, the diserote mathematics strategy for the programming of the automatic MO calculation to a whole class of compounds as well as the other aspects have been demonstrated in this paper. In terms of these research, the wholesale molecular orbital calculation (WMO) and the linear notation containing all the topologic information of PAH molecule have been put forward for the first time, so the first example for the structure prediction and enumeration of PAH having truly chemical significance as well as automatic, systematic MO calculation of whole compound class has been realized. Now, this method has been extended successfully to systematic HMO, PMO and SCF-MO calculations of PAH, and applied routinely for the research on the structure-carcinogenic activity relationship in this laboratory.


Accommodation is mediated by the short posterior ciliary nerves (SPCN) through muscarinic innervation to ciliary muscles. We report a case of an 18-year female who presented with glare and loss of near vision in both eyes after barrage laser to the peripheral retina for multiple lattices with atrophic holes. Before laser, both eyes (OU) best corrected visual acuity (BCVA) with myopic correction was 20/20. After 1 week post-laser, near vision decreased to OU N18, and pupils were dilated and sluggishly reacting. A working diagnosis of bilateral accommodative and pupillary paralysis secondary to laser-induced damage to SPCN was made. We rehabilitated her with topical 1% pilocarpine drops for a month and she recovered. This is one of the few case reports of internal ophthalmoplegia following a barrage laser in a myopic patient. Another uniqueness is the use of 1% pilocarpine drops as a temporary rehabilitation for near vision correction.


Dollhouse play promotes children's creativity and sociality. Implementing a virtual dollhouse in a computer screen offers a more attractive type of play because it removes restrictions on the movements of dolls and the settings of play. However, this method typically compromises the benefits of real doll play. By combining real doll play with a virtual dollhouse, it is possible to incorporate the advantages of both types of play. We develop a virtual dollhouse in a computer display that can be used with real doll play on a tabletop. To connect the real (tabletop) and the virtual (computer display) world, we created a device named "GetToyIn" for users to move their toys (dolls) in and out of the virtual dollhouse. Observations of children aged 4 to 10 years old playing with our dollhouse confirmed that they could understand and operate the design model.


Dasheng Third Textile Company in Hai'men was established later than the other two,and is had a lot of new equipment.When it came into operation in 1921,the golden times for textile industry passed.So this company suffered a lot but continued to operate by debts and hardships.From 1925 and on,it gained profits for 10 years continuously.According to the archives of the company(published ones and inner ones),we edited and organized the balance sheets and income statements of 19 years,so as to systematically explore the experience and drawbacks of the company with statistics and records of board meetings.


While diversity is considered a condition for just and thriving neighborhoods and cities, planners often face challenges in creating and maintaining such neighborhoods, ensuring they remain inclusi...


The objectives of the project were to develop expression vectors using the Sleeping Beauty transposon technology and the genetic border elements to provide both enhanced integration rate and stable transgene expression, and to evaluate the application of such vectors in farmed fish such as catfish and carp. The panel recommended adding the objective of evaluating the endogenous transposable elements, particularly in catfish, in order to evaluate the applicability of the expression vectors while reduc1ng efforts in real production of transgenic fish considering the focus of the project was to develop the vector and evaluation of its applicability, not producing transgenic fish. Efficient production of transgenic farmed fish is hindered by two major problems: mosaicism due to delayed integration after single-cell stage, and silencing of transgene expression. In this project, we proposed to combat these problems by coupling the Sleeping Beauty transposon technology that can enhance integration rate and the border elements that can insulate transgene from position effect. Our major objective was to develop a new generation of expression vector that contains both of these elements. We have developed expression vectors containing both the Sleeping Beauty transposon signals, inverted repeats and direct repeats (IR and DR, respectively), and the border elements, scs and scs'. Growth hormone minigene has been cloned into this vector for applications of such vectors in growth enhancement. Luc reporter gene has been also cloned into this vector cascades for relative easy evaluation of transgene expression. Transgenic fish have been produced using these expression vectors in both catfish (US) and carp (Israel). Much effort was also devoted to evaluation of the endogenous transposable elements in catfish as recommended by the BARD grant panel. Multiple families of Tcl-like transposons were identified from catfish. Surprisingly, many Tc I-related transcripts were identified. Among these transcripts, both the sense and antisense transcripts were present. Some of the transcripts may be useful for development of novel transposase-based technology for aquaculture applications in the future. This project has both scientific and aquaculture implications. First, to develop expression vectors containing both IR/DR and scs/scs' repeated elements have been reported being extremely technically difficult due to excision of the repeated sequences by the E. coli host during cloning processes. We have successfully constructed this advanced vector that contained very complex cascades for both gene integration and gene regulation. We have produced transgenic fish using such vectors. This advanced expression vector should be useful for production of transgenic fish. By simply replacing the growth hormone gene, any gene of interest can be readily inserted in this vector. Thus this vector should provide technological possibility for early integration and stable expression of any economically important genes in aquaculture. We have also evaluated the applications of the Sleeping Beauty-based vectors in terms of the impact of gene size and found that the size of trans gene drastically affects transposition. The system will be only useful for transferring genes smaller than 5.6 kb. We have also identified novel transposase-related transcripts that may be useful for the development of novel transposase-based technologies for general scientific research and for aquaculture applications.


Introduction: Flood disasters are known all over the world to bring along with them

foodborne, waterborne and in some cases airborne diseases which are caused by a

variety of bacteria that infect man and animals.

Objective: A study was conducted to determine the 16S rRNA bacterial biodiversity of

the flood water that affected different parts of Kota Bharu, Kelantan in December, 2014.

Methods: A total of 31 water samples in 50ml sterile containers were collected from 6

different locations (5 samples from each of Taman Bendahara, Kampung Tok Sedang,

Kota Bharu clock roundabout, Kota Bharu mall area, Tesco mall area and 6 samples

from Jalan Kuala Krai) for bacteriological analysis by inoculating into blood agar and

nutrient agar using sterile swabs. Different bacteria were identified from the cultures that

grew within 24-48 hours, using colony morphology, differential/selective media and

biochemical tests. The isolated bacteria were sent for DNA Sanger sequencing.

Sequences with low trace score (<20) were removed, sequences were trimmed, capped

(pair-wise assembled) and the 16S biodiversity was analyzed using the 16S Biodiversity

Tool of Geneious R8.1(Biomatters) for windows 8.

Results: The results revealed 22 genera of bacteria belonging to 12 families:

Moraxellaceae (10%), Aeromonadaceae (8%), Comamonadaceae (13%),

Neisseriaceae (2%), Bacillaceae 1 (16%), Staphylococcaceae (8%), Bacillales Incertae

Sedis XII (3%), Bacillaceae 2 (3%), Streptococcaceae (2%), Flavobacteriaceae (2%),

Enterobacteriaceae (25%) and Pseudomonadaceae (10%).

Conclusion: The isolation of some strain of bacteria in the water during recent flood

occurrence had never been reported previously. It needs to be taken into consideration

for epidemiological study of flood pathogens to determine the future public health

implications.


Nine isolates of unicellular green algae were obtained from six geographically separate desert microbiotic crust communities in western North America. Microscopically, eight isolates strongly resembled unicellular forms of Scenedesmus obliquus (Turpin) Kützing. They are oval or crescent shaped, often flattened on one side, with knobby cell apices. SEM indicated a lack of wall ornamentation. Fine filaments connecting cells pole to pole were observed in some isolates, as previously documented in Scenedesmus (Dactylococcus) dissociatus and S. obliquus. The ninth isolate was spherical, without knobby apices or connections between cells, and was similar to unicellular forms that were originally classified as species of Chlorella (Scenedesmus vacuolatus and S. rubescens). None of the isolates formed coenobia in liquid culture. Phylogenetic analysis of the 18S rRNA gene placed all desert isolates in the genus Scenedesmus, separating them into two or three weakly resolved groups along with published sequences of other Scenedesmus isolates. Phylogenetic analyses of the internal transcribed spacer region revealed well‐supported lineages of desert algae that were unsupported with 18S data alone. The eight S. obliquus‐like desert strains formed two distinct clades that excluded the S. obliquus strains from geographically widespread nondesert habitats. The ninth strain was outside of the S. obliquus group, associated with S. raciborskii and S. pectinatus. These results demonstrate three lineages of Scenedesmus from desert soils and provide robust support for the presence of cryptic species in S. obliquus, a morphospecies that is said to have a cosmopolitan distribution. Three new species of Scenedesmus are described.


Since the first nationwide movement control order was implemented on 18 March 2020 in Malaysia to contain the coronavirus disease 2019 (COVID-19) outbreak, to what extent the uncertainty and continuous containment measures have imposed psychological burdens on the population is unknown. This study aimed to measure the level of mental health of the Malaysian public approximately 2 months after the pandemic's onset. Between 12 May and 5 September 2020, an anonymous online survey was conducted. The target group included all members of the Malaysian population aged 18 years and above. The Depression Anxiety Stress Scale (DASS-21) was used to assess mental health. There were increased depressive, anxiety and stress symptoms throughout the study period, with the depression rates showing the greatest increase. During the end of the data collection period (4 August–5 September 2020), there were high percentages of reported depressive (59.2%) and anxiety (55.1%) symptoms compared with stress (30.6%) symptoms. Perceived health status was the strongest significant predictor for depressive and anxiety symptoms. Individuals with a poorer health perception had higher odds of developing depression (odds ratio [OR] = 5.68; 95% confidence interval [CI] 3.81–8.47) and anxiety (OR = 3.50; 95%CI 2.37–5.17) compared with those with a higher health perception. By demographics, young people–particularly students, females and people with poor financial conditions–were more vulnerable to mental health symptoms. These findings provide an urgent call for increased attention to detect and provide intervention strategies to combat the increasing rate of mental health problems in the ongoing COVID-19 pandemic.


This is the third one of a series of articles on the exact WKB analysis of higher order Painlevé equations (PJ)m with a large parameter (J = I, II, IV; m = 1, 2, 3, . . .); the series is intended to clarify the structure of solutions of (PJ)m by the exact WKB analysis of the underlying overdetermined system (DSLJ)m of linear differential equations, and the target of this paper is instanton-type solutions of (PJ)m. In essence, the main result (Theorem 5.1.1) asserts that, near a simple P -turning point of the first kind, each instanton-type solution of (PJ)m can be formally and locally transformed to an appropriate solution of (PI)1, the classical (i.e., the second order) Painlevé-I equation with a large parameter. The transformation is attained by constructing a WKB-theoretic transformation that brings a solution of (DSLJ)m to a solution of its canonical form (DCan) (§5.3). 2010 Mathematics Subject Classification: Primary 34M60; Secondary 34E20, 34M40, 34M55, 33E17.


Abstract The serious drawback of traditional flow mapping commonly representing geographical movement with straight lines of varying widths is a visual cluttering problem. To resolve these issues, several alternatives reducing the problem or enhancing pattern detection have been suggested. Despite being successful in some aspects, they have their shortcomings such as partial representation or misrepresentation of geographical movement and difficulty in interpreting visualized results. In addition, flow mapping functionality has yet to be fully implemented in modern geographic information systems (GIS) applications. Given these problems, this paper proposes the new designed symbols for improving the traditional flow mapping and develops a flow mapping module implementing them within a commercial GIS software package. Application results demonstrated that the developed module can represent gross, net, two-way and location-specific flows from a single dataset efficiently and can make better flow maps with the alternative symbols. The alternative symbols successfully reduced the visual overlap of symbols and improved the estimation of values.


This paper describes the different types of performance indicators necessary for the evaluation of intermodal transport performance and are identified and analyzed. Based on them, methods and models that are able to evaluate the quality performance of the terminals are elaborated, as it is related to the types of equipments and organization schemes in place. The methods comprise models for the evaluation of different conditions. The first is an analytical hierarchy process model to assess the relative importance of overall performance of existing conditions. The second and the third are models to evaluate the performances of changes in terminals: One is evaluating changes in performance due to the introduction of new technologies; and the other is evaluating the impact on quality performance due to changes in organizational procedures. The first and second models were calibrated for European terminals, using data collected from 42 major European terminals, complimented with extensive interviews. The third was tested with a demonstration case carried out in a leading European Terminal, the "Quadrante Europa" terminal in Verona Italy.


To study the association between the Hammersmith Infant Neurological Examination (HINE) at age 2 years and neurocognition at age 11 years in children born very preterm. We hypothesized that the HINE at 2 years would be associated with neurocognition, that is, neurological, motor, and cognitive outcomes at 11 years.


Surface water pumps have been operated and monitored at TVA's Douglas Dam since 1987. The purpose of these pumps is to improve the dissolved oxygen (DO) content of the hydropower releases. The epilimnetic DO content is a major input variable for a properly designed surface water pump installation at a hydropower facility. Changes in this variable directly affect the performance of the pumps. Therefore, epilimnetic DO and the reasons for its changes are of interest to those using surface water pumps for reservoir release improvements. Graphs are presented that document the continuous changes in the epilimnetic DO content at Douglas Reservoir. Reasons for these changes include diurnal cycles, sunlight variations, wind mixing, and algal population densities. The effects of these changes on the performance of the surface water pumps are discussed.


With the development of WeChat, more and more shopping malls choose WeChat official account to issue preferential information, attract consumers' attention and improve the communication effect. As a reflection of the spread of information in shopping malls, the reading volume of WeChat official account's articles is the goal of this study. Reading volume is affected by many factors. The study discusses two aspects: historical data and the statistical characteristics. Considering the time and space dependence in the articles, this paper proposes a hierarchical Long Short-Term Memory(LSTM) model. The low-level network modeling time dimension features, and the high-level network modeling space dimension feature. The prediction only based on statistical features does not include the historical reading data, it has a good fitting result for the short-term model. The prediction only based on historical data can better predict the long-term growth trend, but loses the influence of the title and other features. In order to solve the limitations of the two methods, this study proposes a hybrid prediction model to predict the reading volume based on historical data and statistical characteristics. Experiments show that the method proposed in this paper has better prediction accuracy.


Due to the distortion of filter gain matrix and high calculation complexity associating with nonlocal effect if symmetric sampling is adopted in the UKF-SLAM algorithm, the UKF-SLAM algorithm adopting square root and single row sampling method based on the proportion and mini-skewness is proposed. The advanced algorithm puts the square root of covariance matrix into iterative computation instead of covariance matrix and adopts the optimized single row sampling strategy based on the proportion and mini-skewness. The experimental results show the algorithm can improve the estimation accuracy of feature map and the pose of robot, besides, that can reduce the complexity and increase stability of the algorithm.


We consider the problem of estimating the stress-strength reliability when the available data is in the form of record values. The one parameter and two parameters exponential distribution are considered. In the case of two parameters exponential distributions we considered the case where the location parameter is common and the case where the scale parameter is common. The maximum likelihood estimators and the associated confidence intervals are derived.


Abstract This article focuses on the societal context of factors that influence life chances. It links patterns of mortality to region, site of habitation, and race. Survivorship is also discussed in terms of certain key changes in technology and mores of American society. Finally, 15 major dimensions affecting the length and quality of life are presented. They range from individual behavior (for example, smoking and alcohol or drug abuse) to societal policies influencing family planning and control of toxic agents. Each is discussed regarding prevalence and goals to reduce that prevalence.


Ocean warming events, such as the recent 2015 El Niño in the California current ecosystem, and demanding life stages, such as reproduction, can cause chronic stress in sea lions. We demonstrate that stress hormones are associated with metabolism and immune markers in chronically stressed animals.


RED BLOOD CORPUSCLES. Mr. Malassez notices a general tendency of these bodies to diminish in number and increase in size in the lower animals. The following figures indicate the estimated number to a cubic millimetre; in the goat, 18,000,000; in the camel, 10,000,000; in man, 4,000,000; in the porpoise, 3,600,000; in birds, 4,000,000 to 1,600,000; in osseous fishes, 2,000,000 to 700,000, and in cartilaginous fishes, 230,000 to 140,000.


Invited commentary on the article "For Safety's Sake: A Case Study of School Security Efforts and their Impact on Education Reform" by Rachel Garver and Pedro Noguera. Disciplines Education Comments For Safety's Sake: A Case Study of School Security Efforts and Their Impact on Education Reform by Rachel Garver and Pedro Noguera. This journal article is available at ScholarlyCommons: https://repository.upenn.edu/gse_pubs/483 Public schools in America have, in many ways, become the solution of choice for many, if not all, of our social ills. Indeed, it almost seems that, for every social ill, we design a program for schools to implement to solve it. If children need to be vaccinated, fed, clothed, provided health care, body mass index calculated, etc., we can count on somebody to develop a "program" to address that social ill and for our state legislators to mandate its application in schools. On one reading, this seems more than reasonable. After all, where better to provide health and other public services to children than in the institution where they are required to be? Moreover, schools cannot carry out their primary mission—educating America's youth—if those youth are hungry, sick or "acting out." And yet, this approach may be an example of what H.L. Menken means when he is famously quoted as saying, "There is always an easy solution to every human problem—neat, plausible, and wrong." Indeed, there are more than a few problems with using public schools as the preferred solution-space for these and other social ills, two of which bear repeating in the current context. First, adding those activities to the work of public schools can divert resources—fiscal, programmatic, and human and social capital—from the mission of schools. Second, and equally important, framing those issues as technical problems to be solved rather than as adaptive issues to be worked through reduces the likelihood that we will successfully address them. The distinction between technical problems and adaptive issues is well worth exploring. A technical problem, such as a broken arm or crashed computer, is one that has a clear solution: setting the bone and putting it in a cast, for example. Human problems are rarely technical. They are more likely to have multiple sources and require expertise from a variety of fields to address, from experts who adapt their knowledge to the specific context and circumstances. Adaptive leadership recognizes that "one size" never fits all. Garver and Noguera have provided us with an insightful and useful case study of what can happen when administrators respond to a crisis situation—in their case, "violent conflicts between Asian and Black students," in predictable ways: in an effort to improve student safety, the district spends precious resources to dramatically improve security measures—more security cameras, increased police presence, stricter i It is important to note that all actors in human situations have a kind of expertise. In Seacrest, students and community members had expertise that could ultimately prove essential in addressing the issue behind the specific behavior problem. 1 Sokoloff: Commentary on: "For Safety's Sake" Published by DigitalCommons@The Texas Medical Center, 2012 discipline policies. That these measures have an almost immediate positive effect seems, in one view, to support the decision to focus on security and to justify the expenditures. And yet, as Garver and Noguera demonstrate, that success comes at some rather significant costs—fewer resources to support the instructional program and professional development, and dramatically reduced emphasis on other aspects of education (e.g., content knowledge, critical thinking and moral reasoning, social-emotional support for students, etc.). Among the educational and social consequences of this dramatically-increased policy and practice focus on security is less emphasis on learning and on school climate. One could argue that the phenomena Garver and Noguera document in their case is a direct consequence of the way the violent incidents were framed by all of the actors: district administration, the media, and some, if not all, factions in the community. Framing the incidents as discipline or behavior problems is an example of one kind of mistake managers (and leaders) typically make when they name or frame problems. In this case, the mistake is framing the issue/problem/challenge in terms of preferred solutions. The moment the problem was defined as a discipline or behavior problem, the solution of stricter discipline policies and more rigid enforcement is almost inevitable. Jentz and Murphy argue that it's natural for leaders to respond to "Oh, no!" moments—and make no mistake that violent incidents such as those in the Gaver and Noguera article are "Oh,no!" moments—by imposing preferred solutions. At such times we expect, and almost demand, the imposition of a solution, if only to contain the situation and create some safety amidst the confusion, restore calm and, perhaps, build confidence. In this sense, responding with increased security and closer enforcement of district policies and behavior code was a necessary first step. But using discipline/behavior as the primary (or only) framing treats a wicked problem as if it were a tame one, resulting in applying technical managerial solutions when adaptive leadership is required. A richer framing of the situation would have gone beyond a singular focus on student behavior, and might have had the following characteristics: clarifying multiple sources of the problem, pointing to ii Garver and Noguera seem to use "security" and "safety" interchangeably. Whether the two are interchangeable might well be worth investigating. Not all things that increase my security increase my sense of being safe. Indeed, increasing security measures such as more sensitive metal detectors and an increased police presence might actually make people feel less safe. But that's a discussion for another time. 2 Journal of Applied Research on Children: Informing Policy for Children at Risk, Vol. 3 [2012], Iss. 2, Art. 14 http://digitalcommons.library.tmc.edu/childrenatrisk/vol3/iss2/14 multiple potential outcomes, allowing for multiple approaches to solutions, making sense to people with different perspectives and identifying the kinds of information that might be helpful in developing solutions. For example, a rich, multifaceted framing of the "problem" at Seacrest would have included reference to classroom instructional methods, school cultures, the separation of different ethnic groups and not just "student behavior" or "discipline." In this way, the framing might have made more sense to students, teachers, parents and community members. It would also have pointed to the need to collect additional data about those facets of the issue and lead to developing a multifaceted strategy for addressing the issues. Developing a framing with such characteristics would require a different kind of leadership than Garver and Noguera imply was provided in the case they describe. Heifetz and Sinder refer to this as adaptive leadership, which would require bringing stakeholders together to reframe the issue and developing ways of addressing the issue that would engage all stakeholders as part of the solution space. Jentz and Murphy and Yankelovich provide two models for this work. Jentz and Murphy propose what they call Reflective Inquiry and Action (RIA). RIA has five steps and enables leaders to pursue their goals, values and judgments while enlisting others to help them make sense of difficult situations. Indeed, the key guiding principles behind RIA— embracing your confusion, structuring a process for moving forward, and listening reflectively—are ways of maintaining authority while exercising adaptive leadership. While the RIA process is designed primarily for what they call "micro" work in private meetings between individuals and small groups, they also provide an instructive case application to the daunting "macro" challenge of educating all children in every school. Daniel Yankelovich outlines what he calls "the public learning" model, which moves from awareness and a sense of urgency to working through the variety of choices for action, to resolution which involves sustainable public judgment. They key to Yankelovich's public learning model is the middle, or "working through" stage, in which leaders convene diverse stakeholders for deliberative problem identification, including identifying alternative definitions of the problem, and identifying different solutions. This includes explicitly identifying the values at play in different interpretations of the issues and solutions and then working through the tensions and the trade-offs people are and are not willing to make to reach sustainable judgment. 3 Sokoloff: Commentary on: "For Safety's Sake" Published by DigitalCommons@The Texas Medical Center, 2012 Like the RIA model, this requires interactive leadership and engaging a wide range of stakeholders to work together, bringing the public's wisdom to add value to that of "...experts to struggle together with conflicting values and priorities to arrive at a public judgment of how they will work together to address the problem at hand." Interestingly, using either the RIA or "public learning" model could have created a richer framing of what the administrators at Seacrest High School, or the central administration of the city within which it resides, called a "security" problem. It could well have involved a broad range of stakeholders in looking at that "security" and "safety" in a broader context—including the context of teaching and learning, the culture of the school, and the relationship of the school with the communities it serves. It would have broadened the conversation in ways that could have led to the sustainable school improvement Garver and Noguera argue was ignored in the actual case. 4 Journal of


Objective To explore the treatment of deep-vein indwelling catheter in infant patients with subdural hematoma and hydrops. Methods Deep-vein indwelling cather wes used in treatment of 19 cases infant patients with subdural hematoma and hydrops. These cases include acute subdural hematoma(9 cases), chronic subdural hematoma(6 cases), subdural collection of fluid(4 cases).Deep-vein indwelling cather which set in subdura and constantly drain is to treat infant patients with subdural hematoma and hydrops via anterior fontanelle puncture. Constantly drainage last 3~5 days.Results All puncture and deep-vein indwelling catheter were successful. The cranial CT was rechecked in 1~7 days after operation. Subdural hematoma and subdural collection of fluid were nearly removed.All patients are survival. Conclusions The treatment of deep-vein indwelling catheter in infant patients with subdural hematoma and hydrops is safe and effective.

Key words:
Deep-vein indwelling catheter; Infant; Subdural hematoma; Subdural hydrops; Anterior fontanelle


Compared to styrene-butadiene-styrene copolymer (SBS) as the most used asphalt modifier, polyolefin elastomer (POE) has not been used because of the phase separation during hot storage. The structure and property of POE and POE/crumb tire rubber (CTR) blends modified asphalts were studied by optical microscopy, rheological measurements and aging resistance, respectively. POE particles dispersed irregularly in the bituminous phase below 4 wt% POE, and a continuous POE phase formed over 6 wt%. The screw extrusion and the content of the compatibilizer significantly affected the hot storage stability of the POE/CTR blends modified asphalts. The CTR and POE mutually stabilized in the asphalt by screw extrusion in the presence of glycidylmethacrylate functionalized polymer. The extruded POE/CTR dispersed more finely in the asphalt than controlled POE. The stabilized POE/CTR modified asphalt had better aging resistance than regular SBS modified asphalt.


After nearly two decades of investigations at Fort St. Joseph, historical archaeologists have revealed the contours of everyday life at one of the most important French colonial outposts in the western Great Lakes region. Initially founded as a mission along the St. Joseph River in the 1680s, the French soon established a settlement amidst their Miami and Potawatomi allies, and the site became a strategic stronghold before it was abandoned in 1781. For many years, the site eluded archaeological discovery, until 1998 when Western Michigan University archaeologists identified material evidence of the long-lost Fort. In 2002, after a century of searching for the Fort, subsurface testing revealed undisturbed archaeological deposits in the form of fireplaces, pits, and trash middens—definitive material evidence of Fort St. Joseph. Under the auspices of the Fort St. Joseph Archaeological Project, subsequent fieldwork and analysis have focused on examining the materiality of the Fort and the relationships between the Fort residents and local native populations. Fort St. Joseph Revealed employs archaeological and documentary sources to examine the history and culture of a fur trade society on the frontier of New France. This collection of papers is the first compilation of analyses derived from documents, cultural features, plant and animal remains, and various artifacts both to explore the importance of Fort St. Joseph in the past and in the present and to synthesize data on the colonial frontier from the perspective of a single place in the western Great Lakes region.


For certain Dirichlet series almost surely(a.s.)of order(R) ρ∈(0,∞)in the right-half plane,a.s.every point of the imaginary axis is a Borel point of order ρ+1 and with no finite exoeptional value.


In this paper, the study represents a theoretical conceptualization on the potential improvements to interpret and devise under the notion of quantum mechanics & AI utilizing psychology for social robots. The framework is elaborated in regard to the development of emotions encoded through information and possibilities, which manipulates the use of transitions of these emotions in states through the Quantum & AI measurements. To support the development, work introduced is an interpretation of quantum mechanics, linked with quantum science, systems science, and Conceptualized Neural Network. The understanding of these emotions are expected to impact the technical capability of robots in a specific aspect to sense, capture, and act in an environment relied on optimization of quantum bits, where a robot, perform these emotions through a network which will allow interaction with the given target, changing the robot's state of response according to optimization and gates from target itself, computing the robot's emotional performance based on measurement and mathematical expressions changing in accordance to the available information. This method will help to emphasize its viability and effectiveness in the synthesis of emotional intellect in social robots.


We analyzed the variables affecting the adoption or nonadoption of precision farming technologies in cotton production using survey data collected from 14 U.S. states. Results from the nested logit model indicated age has a negative effect on adoption but household income, farm size, and perception that precision farming is profitable have a positive impact on precision farming adoption. We considered 13 information gathering technologies in this study: yield monitor with GPS; geo-referenced soil sampling – grid and zone; aerial photos; satellite images; soil survey maps; handheld GPS/PDA; COTMAN plant mapping; electrical conductivity; digitized mapping; automatic section control or auto-swath for planters; automatic section control or auto-swath for sprayers; and GPS guidance. We used tetrachoric correlation to identify the correlation among those individuals who have adopted/not adopted these 13 information gathering technologies. We identified three unique bundles of technologies -two of these three bundles were analyzed in this study. In bundle 1, there were three technologies: Aerial photos, satellite images and soil maps. In bundle two, there were two technologies: zone soil sampling and electrical conductivity. A multivariate probit model was used to identify the factors affecting the adoption/nonadoption of these technologies within the bundle setting. We observe that variables commonly known to positively affect technology adoption are education, information, size, and computer use. Age of the farmer is only variable that causes a negative effect on technology adoption. 42


A recent report from the Institute of Medicine concludes that vitamin D has no benefits beyond its effects on bone health, …


Views of simulacrum-image and Cuo zong (obversion and inversion) are two inventions in LAI's studies of Change. The connotations of the images so-called by LAI Zhi-de contain two levels of meanings: simulacrum and imaginablity. This point of view is an important development from the theory of simulation revealed in the Commentary of Xi Ci (Great Treatise) and particularly from ZHU Xi's imagery. It is in actuality a pondering and explication on the possibility of establishing the theory of simulation and how to establish it. Cuo formally refers to two mutually obversed hexagrams. Zong possesses two forms: One refers to the changes of the four cardinal trigrams (i.e.≡,■,■,and■) in the upper or lower positions of a hexagram; the other refers to the relationship between a hexagram and its inverted hexagram. It seems that the former case of the inversion had never noticed and explicated by scholars. Though the forms of Cuo and Zong differ from each other,the metaphysical principle for the establishment of them is principle of the changes between Yin and Yang: Cuo in actuality depends on the mutual oppositeness between Yin and Yang,while Zong reveals the flowing of Yin and Yang between the upper and lower positions. In LAI's studies of the Change,Cuo and Zong are not only formulae of images,but also the inner principle of the construction of the hexagrams' orders. However,LAI's view of simulacrum-image and theory of Cuo and Zong are of great significance in the history of the Yi studies.


Drawing on many years of parish ministry experience, John S. Mansell offers clear, insightful guidance on how to prepare for and conduct funeral services, how to minister to those who have lost a loved one, and how to lead the congregation in caring for the families of those who have died, as well as numerous other pastoral duties associated with funerals. Included are sermon briefs appropriate to different kinds of funerals, detailed lists of tasks to be performed or assigned related to pastoral care of the bereaved, and sample funeral services and service outlines.


The women's movement during the 30 years before new China has got great achievements, but some defeats do exist. First, social yoke which shackled women have been smashed but spiritual yoke still exist. Second, the slogan of "Men and Women Being Equal" caused women subject consciousness to be depreciated. This hindered the realization of the ideal of men and women being equal. Last, depending psychology confines the improvement of women's quality.


PROBLEM TO BE SOLVED: To protect data in a portable computer by preventing any one of selected files from being non-ciphered till a secret key is inputted in order to obtain a ciphering key by means of an audinary sentence and, then, used. SOLUTION: When the file is ciphered and, then, a user restarts the usage of a computer, the user has to correctly input the secret key 9. Unless the user inputs the correct secret key 9, a file protecting agent 12 urges the user to input the secret key 9. This rule continues up to three times, for example, till a limit being the correction impossible parameter of a program. Unless the user inputs the secret key 9 well within the range of the limit, the file protecting key 12 erases an algorithm which is used for scrambling the secret key 9 at the time of scrambling a cipher key 3. The cipher key 3 is not obtained except scrambling by the secret key 9. COPYRIGHT: (C)1997,JPO


Agile and lean management practices (which we define broadly to include Scrum, XP, Lean Startup and other related approaches) roughly triple the success rate of software projects over traditional management approaches [1]. Despite these results, the software industry continues to start new projects using traditional approaches. Because software projects contribute so broadly to the human condition, research on agile methods may produce significant productivity gains. The impact extends beyond software, agile manufacturing [2] and agile organizational strategy [3] share many fundamentals with agile software.


A Wiener weighting adaptive time delay estimation algorithm based on frequency domain is presented. It is made up of two steps of frequency domain adaptive filters, the first step is the Wiener weighting to the input signals, and the second one is the adaptive time delay estimation in the frequency domain. In order to improve the performance of the algorithm in the low signal to noise ratio, the algorithm utilizes a combined filter transfer function to weight the phase data before fitting the phase data to estimate the time delay. The simulation results of the real data radiated by the helicopters show the effectiveness of the algorithm.


We thank Dr Chong and colleagues for their comments regarding our paper on quinidine for migrating partial seizures of infancy (MPSI), also known as epilepsy of infancy with migrating focal seizures. In their letter, they describe a 6-year-old child with a history of intractable epilepsy secondary to a KCNT1 mutation. The child did not have an MPSI phenotype, and did not respond to treatment with quinidine. Although quinidine (or another, more selective, KCNT1 antagonist) remains a promising potential therapy for MPSI secondary to KCNT1 mutations, we agree that further study is required both to assess efficacy and to identify the appropriate population for treatment. We agree with Dr Chong and colleagues that possible contributing factors to the lack of effect of quinidine were the older age of their patient and lack of an MPSI phenotype. As we suggested in our initial report, for a variety of reasons older patients may not respond as well as younger patients. We also note that the recent study by Mikati et al found a significant effect of quinidine in a patient with an MPSI phenotype, but not in a second patient with a nocturnal frontal lobe epilepsy phenotype. Efficacy of quinidine for MPSI may depend on the underlying genetic mutation as well as the age of the patient and the epilepsy phenotype, although as of yet there appears to be no clear correlation between genotype and disease severity. Other factors influencing the effect of quinidine might include the dose, serum drug level, and background genetic effects. We note that in our published case report, seizure freedom occurred when the serum drug level was maintained at 2 to 5 mg/ml, which is higher than the level reported by Chong et al. Although at this point there is no evidence that higher levels are superior to lower levels, a dose-finding study would be necessary to clarify optimal dosing and levels. In addition, further studies are necessary to identify other factors that might contribute to treatment efficacy of quinidine. To this end, we have created a registry of patients with MPSI and other KCNT1-related epilepsy that will attempt to answer some of these questions. Since the initial patient described in our report, we have presented data on 14 additional patients with MPSI secondary to KCNT1 mutations treated with quinidine at the American Academy of Neurology meeting in 2015. In that case series, we noted that 7 of 14 patients with KCNT1-related MPSI treated with quinidine had a significant decrease in seizure frequency or became seizure free, whereas quinidine had little or no effect in the other 7 patients. It should be noted that case reports or series of this sort are likely to provide an unreliable estimate of actual efficacy due to placebo effect and reporting bias, and randomized controlled trials are still necessary to evaluate the efficacy of quinidine before it should be widely used clinically outside of a study. One of the challenges of developing treatments for rare diseases such as KCNT1-related epilepsy is the recruitment of enough patients to conduct studies to definitively assess efficacy. Although we suggest that a definitive randomized controlled trial of quinidine is necessary and are working to develop this, in the absence of such a trial we would strongly encourage neurologists working with patients with MPSI or other KCNT1-related epilepsy to contact the authors at Children's Hospital of Philadelphia for enrollment in our registry. Utilizing this registry, we will be able to characterize the natural history of KCNT1-related epilepsy in preparation for a planned trial, and collect preliminary data on efficacy, side effects, and likely effective dose of quinidine.


WRITING INSTRUCTION: NEW FOCUS ON AN OLD CHALLENGEThe 2007 and 2011 National Assessment of Educational Progress data indicate that a significant percentage of American students struggle with writing. In 2007, only 35% of eighth grade students performed at or above the proficient level and in 2011, only 27% of eighth graders reached this goal. A consistent and significant achievement gap exists: white students outperform Black and Hispanic students; females outperform males; and students who do not qualify for free and reduced lunch outperform those who do. This disparity has significant implications; writing is a "threshold skill" (National Commission on Writing for America's Families, School, and Colleges, 2004, p. 3) for both employment and promotion. Further, the Common Core standards (National Governors Association & Council of Chief School Officers, 2010) provide a new emphasis on writing instruction with ten writing standards explicitly devoted to preparing students for college and career writing demands. Standards, assessment, and accountability have been named the "most powerful drivers of education systems" (Council of Chief State School Officers, 2013) indicating increased assessment pressure on writing and posing challenges for teachers previously working under the reading and math emphasis of the No Child Left Behind Act. These national reports and reform initiatives reveal a critical need for effective writing instruction that can empower struggling adolescents.Research indicates that the writing workshop "has become the prominent paradigm for the teaching of writing in the United States" (Harris, Graham, & Mason, 2006, p. 300). Although there is no single definition of the writing workshop classroom, general characteristics include: teaching writing as a process; writing for real audiences; high levels of student choice, interaction, and ownership; examination of model texts; teacher modeling with a focus on writing craft; and classroom publishing (Atwell, 1998; Fletcher & Portalupi, 2001, 2007; Portalupi & Fletcher, 2001; Pritchard & Honeycutt, 2006; Ray, 1999). Composing, drafting, and revising texts, inherent parts of the workshop approach, are also emphasized by the Common Core standards. Writing standard five requires students to "develop and strengthen writing as needed by planning, revising, editing, rewriting, or trying a new approach" (National Governors Association & Council of Chief State School Officers, Standard 5, 2010). Taken as a whole, all ten standards require students use a process approach to write a range of texts for a variety tasks and purposes and establish the goal of teaching students to compose complex texts independently by the end of high school. Revision is essential in helping students leam to write independently because it pushes students to critically consider the effectiveness of their work, yet research indicates that revision is frequently overlooked by students and teachers (MacArthur, 2013; Witte, 2013). This study used a pragmatic approach to examine the experiences of one eighth grade teacher and five of her students during instruction designed to foster independent revision behaviors.I begin with a discussion of the research surrounding teaching revision and share the theoretical framework guiding the research design. I then present findings from this qualitative research project and conclude with a discussion of implications for teachers, teachereducators, and future research.A Well-Established Challenge: Teaching RevisionThe extant literature about revision acknowledges the cognitive demands of the process, its underemphasis in classroom instruction, the ineffectual approaches of struggling students, and its inextricable relationship with reading skills (Graham & Harris, 1993; Graham & Perrin, 2007a; Hayes & Flowers 1986; MacAruthur, 2013; Sommers, 1982; Witte, 2013). Studies of adult writers found that revision involves recognizing a dissonance between what is written and what is meant then using specific knowledge about genre, form, organization and idea development to make effective changes (Hayes & Flower, 1986; MacArthur, 2013; Sommers, 1982). …


The article deals with the monitoring of competences, which are formed in the process of teaching the first and second-year students. The use of inter-subject connections in the conditions of competence-based approach to studying in the sphere of higher professional education is analyzed. The succession of monitoring on the stages of professional training of students at higher educational institutions is characterized.


Poly(ethylene glycol) (PEG) is an often used crystallizing agent in screening experiments for protein crystallization conditions. To investigate the influence of poly(ethylene glycol)-4600 on the diffusion process during protein crystal growth, a series of in situ optical microscopy experiments were performed in which the diffusion coefficient was changed by the addition of PEG. Depending on the balance between diffusion coefficient and driving force, lysozyme crystals were found to grow faceted, kinetically rough, or morphologically unstable. In situ observations show the development of a lysozyme crystal from polyhedral stability to instability and back to stability again as the balance changes within one experiment. A stability diagram showing the occurrence of morphological instability based on the starting conditions is presented, showing that kinetic roughening stabilizes the crystal morphology. The results are interpreted in terms of a competition between two-dimensional nucleation at the edges of the crystal and step flow on its surface. In this, surface protein concentration profiles derived from observed crystal shapes are used.


Perhaps, the most exciting rescue, terrestrial or extra-terrestrial, is the successful return of the Apollo 13 crew to Earth in April of 1970. The mission s warning system engineer, Jerry Woodfill, who remains a NASA employee after 47 years of government service has examined facets of the rescue for the past 42 years. He will present "13 Things That Saved Apollo 13" from the perspective of his real time experience as well as two score years of study. Many are recent discoveries never before published in mission reports, popular books or documentary and Hollywood movies depicting the rescue.


PURPOSE: Provided are L-arabinose derivative, L-xylose derivative, and their salts which have an excellent inhibiting effect on a cell cycle regulator in a cancer cell and is thus useful as an active ingredient of a pharmaceutical composition for an anticancer agent. And their preparation method is also provided. CONSTITUTION: L-arabinose derivative of the formula (1) and L-xylose derivative of the formula (2) are condensates of sugar and base in which the sugar portion is not D-form, but L-form. Particularly, preferred compounds of L-xylose derivative are as follows: 1) 4-amino-5-cyano-7-(2,3,5-trihydroxy-beta-L-xylofuranosyl)pyrrolo(2,3-d)pyrimidine; 2) 4-amino-7-(beta-L-xylofuranosyl)pyrrolo(2,3-d)pyrimidine-5-carboxamidine; 3) 4-amino- 6-bromo-7-(beta-L-xylofuranosyl)pyrrolo(2,3-d)pyrimidine-5-carboxamide; 4) ethyl 4-amino-6-bromo-7-(beta-L-xylofuranosyl)pyrrolo(2,3-d)pyrimidine-5-carboxamideoxime HCl; 5) 4-amino-6-bromo-7-(beta-L-xylofuranosyl)pyrrolo(2,3-d)pyrimidine-5- thiocarboxamide; 6) 4-amino-5-cyano-7-(beta-L-xylofuranosyl)pyrrolo(2,3-d)pyrimidine; 7) 4-amino-7-(beta-L-xylofuranosyl)pyrrolo(2,3-d)pyrimidine-5-carboxamide; 8) ethyl 4-amino-7-(beta-L-xylofuranosyl)pyrrolo(2,3-d)pyrimidine-5-carboxamideoxime HCl; and 9) 4-amino-7-(beta-L-xylofuranosyl)pyrrolo(2,3-d)pyrimidine-5-thiocarboxamide.


Cattle slurry solid fraction (SF) was collected from a dairy farm (SF) and composted with increasing rates of Italian ryegrass straw or gorse, in static piles turned only three times. Temperatures increased to a maximum of 65 oC after the first turn in the pile only with SF. In contrast, higher temperatures were registered much sooner in piles mixed with straw or gorse. The addition of these bulking agents to SF increased temperatures and also the initial rates of organic matter (OM) mineralisation. In contrast, potential OM mineralisation and organic N content decreased. REVISTA DE CIÊNCIAS AGRÁRIAS 268 The C/N ratio declined following a similar pattern for all compost treatments, from 32–38 at the beginning of the process, to a value of 13–17 towards the end of composting. Stabilized compost was obtained from raw SF feedstock as indicated by the low compost temperature, low C/N ratio and the small content of NH4 combined with increased concentrations of NO3. The high concentration of OM (784-832 g kg) and total N (28-35 g kg) in final composts in addition to a low electrical conductivity (0.72-1.16 dS m) suggests that SF composts may be effective as soil amendments. The use of straw or gorse contributed to guarantee compost sanitation. Key-words: Compost, mineralisation, nitrogen, organic matter, temperature


The classification of infrared images over polar regions is a difficult task. The algorithm presented uses the texture features of segments. The classification is done by a neural network. The results are promising. About 90% of the pixels are correctly identified.


This work describes preparation process of free-standing alumina membranes used in sensor devices for separation or purification (increased selectivity, and sensitivity) purposes. Nanoporous alumina membranes were prepared using anodic oxidation of aluminium foil in two types of acidic electrolytes and characterized using scanning electron microscopy. Membranes with pore diameters of 90 nm and 30 nm and thicknesses of 115 µm and 163 µm respectively were obtained. Fabrication of membranes with different post-treatment was also done. In this post-treatment process, etching of non-anodized aluminium and opening of barrier layer were replaced with application of reversible potential with equal magnitude as anodization voltage.


Neoclassical growth theory represents growth as an exclusively supply-driven phenomenon. Keynesian economics emphasizes demand-side dimensions. In steady state, demand and supply growth must be equal. Without this, there will be growing excess capacity or excess demand. If supply growth does not respond one-for-one to changes in the rate of demand growth, this requires mechanisms for equilibrating the two. This paper presents a short treatment of the demand and supply growth problem, and uses the theory of balance of payments (BOP) constrained growth to illustrate the problem. The characteristics of the BOP model are dramatically changed by incorporating capacity growth considerations, which illustrates the pitfalls that can follow from failure to model properly the supply–demand balance.


Niacin and lovastatin are lipid-altering agents but differ in physicochemical properties. Niacin (nicotinic acid, pKa of 2.17) is a BCS class 1 drug with the plasma half-life about 20 to 48 min, while lovastatin (pKa 13.49) is classified as BCS class 2 with half-life 4.5 h. This project was originally set to design a tablet containing 250 mg niacin and 20 mg lovastatin. The in vitro dissolution methodology for Niacin ER/Lovastatin tablet was adopted from FDA Dissolution Method Database. During the early formulation stages, lovastatin was found unstable in the acidic medium. When the solvents were prepared as 0.1 N HCl to simulate gastric medium or phosphate buffer pH 4.5 as duodenum medium, unidentified chromatographic peak in addition to the lovastatin peak was recorded in Agilent HPLC software. Since niacin is a rather acidic compound, we felt that from product storage stability viewpoint these two drugs are not to be compounded together. This led to the development of a delayed- then extended-release 20 mg tablet (without niacin) in order to target the release of lovastatin in the small intestine.


We have speculated on the possibility that cold d‐d fusion in transition metals occurs as the result of catalysis by small numbers (consistent with present experimental limits on their non‐observance) of free stable ūū=Q anti‐diquarks (electric charge Z=−4/3, mass greater than some fraction of a GeV, and short‐range strong repulsion with hadrons). A Q would be released in a non‐equilibrium process, catalyze the d‐d fusion at a rate of 1010/Q/s, and then be captured on a heavy element, thus producing bursts of fusion products. The He4+ Q channel should dominate (over the 3 body channels He3+ n+Q, and t+p+Q) so another key prediction is that the burst of He4 should be emitted with a unique energy greater than several MeV (dependent on the Q mass). Bursts of emitted neutrons would have a 3‐body energy spectrum. Regardless of the present cold fusion experiment, the Q hypothesis is attractive in that is could provide power production with (perhaps) relatively low radioactivity, if Q's exist and can be accumulated.


In this paper, we provide an assistive aid for visually impaired people. Fingerprint is the unique identity of any individual. From olden days till today it has been the symbol of uniqueness. This Fingerprint based doorbell security system is implemented using Arduino technology. In this system the database the close circle of the visually impaired person is stored using the Fingerprint sensor as input. This provides them with highest level of security. When the current fingerprint matches with the database, they are marked as authorised and the name is being conveyed to the visually impaired. And if it doesn't, they are conveyed as unauthorised. In the software the fingerprint data, date & time of the entries are listed for future investigation. Thus, this system publishes the name of the one at the doorstep to the visually impaired person inside the house. Index Terms Visually Impaired, Fingerprint


Anemia is a common problem with serious consequences in geriatric patients but the impact of anemia on cognitive function has not been extensively studied. The aim of this study was to evaluate the association between anemia and cognitive impairment in hospitalized geriatric patients at Sanglah Hospital Denpasar. This was a hospital-based analytic cross-sectional study. The data were derived from the medical records of geriatric patients (age ≥60 years) admitted to Department of Internal Medicine Sanglah Hospital Denpsar. A total of 121 elderly patients were enrolled. Anemic status and cognitive function were defined using WHO-criteria and mini-mental state examination (MMSE) questionnaires, respectively. Chi-square or Fisher-exact test was used to test the significance between 2 proportions. The risk was estimated by using odds ratio (OR) and 95% confidence interval (CI). The overall-prevalence of anemia and cognitive impairment among hospitalized elderly patients was 62.8% and 47.2%, respectively. Cognitive impairment was more prevalent in female than male (50.88% vs. 49.12%) and in patients with the age >70 vs <70 years (63.15% vs. 36.84%). We found no significant association between anemia and cognitive impairment in geriatric patient (P=0.32). It was concluded that there is no association between anemia and cognitive impairment in hospitalized geriatric patients at Sanglah hospital. [MEDICINA. 2016;50(3):6-9].


Abstract : Two hundred 2D-binary dividers were evaluated and interconnected. Limited success was experienced with deposited metal and welded interconnection techniques. Jigs, fixtures and techniques employed are detailed.


fied by the usual criteria? If such students could be located, would they profit from an enrichment program in which to participate with &dquo;identified gifted&dquo; students? Further, would any effects of such participation be lasting? These were some of the questions underlying &dquo;Project PATS&dquo; (Potentially Academically Talented Students), a state-funded, trilevel pilot project for youngsters in the middle school grades.


In a two-echelon supply chain system with one retailer,one manufacture and one short life cycle product,the general mathematical model of whether to coordinate and share information is constructed and analyzed when the market demand and manufacture's order completion time are random distributions and manufacture can carry out the order in advance through overtime work or fast transportation.Case analysis and numerical simulation show that supply-demand coordination and information shared can not only increase the whole supply chain system's profit and keep its profit marginal stable,but also increase the products supply in the market.


Natural Sciences and Engineering Research Council of Canada (NSERC, Grant no. 400495). Ontario Ministry of Agriculture, Food and Rural Affairs (OMAFRA, Grant no. 200474)