【Objective】 To investigate the long-term prognosis of the patients with retinal hemangioma associated with von HippelLindau(VHL) disease.【Methods】 Nine patients with retinal hemangioma associated with VHL disease were followed up.The progresses and therapeutic results of retinal hemangioma and other tumors in different systems were observed.【Results】 During a mean9.1 years follow-up period(8-11 years),retinal hemangioma occurred in both eyes of all patients.At the end of follow-up,compared with baseline,the best corrected visual acuity were stable in 12 eyes(66.7%),improved in 1 eye(5.6%),decreased in 5 eyes(27.7%),renal tumor occurred in 5 patients(56.6%) and central nervous system haemangioblastoma occurred in 5 patients(56.6%).2 patients died with renal cell carcinoma during the follow-up.【Conclusion】 In the patients with retinal hemangioma associated with VHL disease,long-term results are stable with prompt early treatments for retinal hemangioma in the eyes.Central nervous system haemangioblastoma and renal cell carcinoma are the most frequent tumors in these patients while the latter has a poor prognosis.Management of VHL disease requires coordination from different medical specialties,periodic surveillance,early diagnosis and prompt treatment.


This is the peer reviewed version of the following article: Atkins, Judi / Introduction: Conflict, Cooperation and the Cameron–Clegg Government. In: Political Quarterly, Vol. 86, No. 1, 2015, p. 81–84., which has been published in final form at https://dx.doi.org/10.1111/1467-923X.12149 This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.


Five times a day in the 83 square mile city of Cairo, over 30,000 muezzins call out the adhan, or call to prayer, calling believers to come and to pray. This Maghrib (sunset) adhan was recorded in the Cities of the Dead (miles long cemetaries), in the neighbourhood of Sayeda Aisha. The recording captures the voices of the muezzins of Cairo, all of whose calls begin a few seconds apart from one another. The muezzins calling from far away mosques and mosques closest to location can be heard: please control the volume accordingly.


Questions: Observations in permanent forest vegetation plots in Norway and else-where indicate that complex changes have taken place over the period 1988– 2020. These observations are summarised in the "climate-induced understorey change (CIUC)" hypothesis, i


In this paper, a virtual instrument (VI) based on LabVIEW (laboratory virtual instrument engineering workbench) is developed for instantaneous harmonic currents detection in three-phase systems. By the generalized dk-qk coordinate transform theory, any term of harmonic current as well as fundamental active and reactive power can be detected effectively and accurately. All of the detecting functions are realized in LabVIEW environment. Compared with conventional instruments, costs for research and development can be substantially reduced while computing speed can be accelerated. Simulation and experimental results prove the feasibility and validity of the developed VI, therefore it can be widely used for real-time harmonic detecting and power quality monitoring. (4 pages)


OBJECTIVE To observe the effect of the kelintong fang on antibacterial and anti-inflammatory.METHODS The commonly bacteria antibacterial effect was observed by using external admixture cultivation to kelintong fang.The anti-inflammatory effect was observed by using subcutaneous injection 1% agar on mice toes only to lead to swelling to calculate the swelling rate.RESULTS All the dose groups of the kelintong capsule had inhibition effect.All the dose groups of the ke lintogn capsule had inhibition effect.The minimum inhibitory concentrations of different bacteria were gonococcus 0.0125 g/ml;Staphylococcus aureus 0.00135 g/ml;diplococcus pneumoniae 0.025 g/ml;beta-hemolytic streptococc and salmonella typhi 0.05 g/ml;Escherichia coli,Shigella dysenteriae and Pseudomonas aeruginosa 0.1 g/ml;Kelintong capsule had certain inhibiting effect to the engorgement in rats toes caused by agar which was more significant role in the high dose group(P0.01).CONCLUSION Kelintong fang has strongly antibacterial and anti-inflammatory effect.


This thesis project develops the pack carburizing process for low carbon steel by using a fluidized bed. This treatment aims to enrich the steel surface with carbon by diffusion. Therefore, a superficial layer with a higher carbon concentration than its core is achieved. As effect, the hardened steel acquires a useful combination of properties such as high surface hardness and wear resistance without losing toughness in its core.
The cementitious mixture used is composed of 90% of activated carbon and 10% of sodium carbonate. Additionally, argon was used for the fluidized bed. Four different cementation tests were carried out by temperature and time variations. Thus, two possible combinations of these parameters were identified as minimum conditions necessary for the proposed process of carburizing which are at 850 °C for 3 hours or at 900 °C for 2 hours.
The main objective is to ensure that the process is successfully developed under the suggested conditions. This can be confirmed by the hardness and total case hardening depth analysis. Regarding the total case hardening depth obtained, it affirms that the process has being carried out correctly, for the depth value reached over 0.8 mm. The total case hardening depth is defined as the perpendicular distance from the boundary surface to the end of the hardened area. Moreover, increased hardness in all tests regarding initial material supplied, confirms the presence of a layer with a higher carbon concentration.
Finally, besides making sure the process was successful, it is important to emphasize the benefits of using a fluidized bed. This technique makes it an excellent alternative to complement the carburizing process since better results are obtained in terms of uniformity and case hardening depth, as demonstrated in this thesis.


Materials and Methods: The quartz sample from a volcanic rock of Japan was used. After correcting the thermal quenching effect, RTL peaks of quartz were separated by the CGCD method cooperated with the general order kinetics. The number of overlapped glow peaks were ascertained by the Tm-Tstop method. The optical sensitivity was examined by comparing the change of intensity on RTL glow peaks measured after exposure to light from a solar simulator with various illumination times.


Review(s) of: Niki, by Tibor Dery (Seeker and Warburg, 1958). Review(s) of: The Gates of Ivory, The Gates of Horn, by Thomas McGrath (Mainstream Publishers, N.Y., 1958). Review(s) of: The Guide, by R. K. Narayan (Methuen, 1958 ).


Simultaneous observations have been made of velocities in the chromosphere (in H..cap alpha..) and in the photosphere (in the nonmagnetic Fe i line lambda5576) of three sunspots. The results reveal waves propagating horizontally outward across the penumbra in the photosphere with about the same period as the running penumbral waves in H..cap alpha.. (250--290 s). The photospheric waves are more intermittent and have higher horizontal phase velocity (by a factor of 2 or more) than the chromospheric penumbral waves. (AIP)


Method for exchanging data, comprising: a broadcast cut to produce cut using displays for access window, and use display, that allows the stations in the list of stations allows the indicator to use about their resource allocation claim of whether it is necessary to receive the first display information, and the access window of the beginning of the second list of stations allowed with the indication of time comprises at least one of a third display. Method also includes at least one exchange of the data among the stations permitted in the access window in accordance with the used marker.


This multimedia database project is the first large-scale collection and description of the signs of Swiss German Sign Language (Deutschschweizerische Gebardensprache, DSGS). The aim of the database is to gather linguistic information on the DSGS lexicon which can serve as a basis for future dictionaries and teaching materials, as well as function as a tool for linguistic research. For each lexical entry, there is information about all of the sign's meanings, its morphological and syntactic characteristic, several categories of usage (geographical and generation variation, style, register) as well as example links to videotaped signed sentences. The information about each lexical item is represented in the database in several different forms: Video clips of the base form of the sign and of signed sentences in which it appears, line drawings, information checkboxes, form notation (HamNoSys and SignWriting), as well as German text.


Optical computational imaging seeks enhanced performance and new functionality by the joint design of illumination, optics, detectors, and reconstruction algorithms. Two remarkable examples discussed here enable overcoming the diffraction limit and imaging through complex media.


Abstract Background The efficacy of dendritic cell (DC) immunotherapy as a single therapeutic modality for the treatment of glioblastoma (GBM) patients remains limited. In this study, we evaluated in patients with GBM recurrence the immune-mediated effects of DC loaded with autologous tumor lysate combined with temozolomide (TMZ) or tetanus toxoid (TT). Methods In the phase I-II clinical study DENDR2, 12 patients were treated with 5 DC vaccinations combined with dose-dense TMZ. Subsequently, in eight patients, here defined as Variant (V)-DENDR2, the vaccine site was preconditioned with TT 24 hours before DC vaccination and TMZ was avoided. As a survival endpoint for these studies, we considered overall survival 9 months (OS9) after second surgery. Patients were analyzed for the generation of effector, memory, and T helper immune response. Results Four of 12 DENDR2 patients reached OS9, but all failed to show an immunological response. Five of eight V-DENDR2 patients (62%) reached OS9, and one patient is still alive (OS >30 months). A robust CD8+ T-cell activation and memory T-cell formation were observed in V-DENDR2 OS>9. Only in these patients, the vaccine-specific CD4+ T-cell activation (CD38+/HLA-DR+) was paralleled by an increase in TT-induced CD4+/CD38low/CD127high memory T cells. Only V-DENDR2 patients showed the formation of a nodule at the DC injection site infiltrated by CCL3-expressing CD4+ T cells. Conclusions TT preconditioning of the vaccine site and lack of TMZ could contribute to the efficacy of DC immunotherapy by inducing an effector response, memory, and helper T-cell generation.


Loblolly pine raised at the North Carolina field site and Ponderosa pine raised at the California field site show differences in their capacity to grown and sequester carbon. The contrast in CO[sub 2] responses between species is related to both environmental differences between the field sites as well as biological differences between Loblolly and Ponderosa pine. We designed an experiment to isolate the biological differences between CO[sub 2] responses of the 2 test species by raising them in common environments at the Duke University Phytotron. Both pine species were raised for 160 days in either 35 Pa or 70 Pa CO[sub 2]. Plants were also raised at 3 levels of N since N is known to affect CO[sub 2] responses of plants. Seedlings were raised in 3.3 1 pots filled with sand irrigated each morning with 1/2 strength Hoaglands solution made with N supplied at NH[sub 4] at either 1 mm. 3.5 mm. or 7 mm. Root, stem, and foliar biomass, whole plant biomass, and leaf area were similar for both species across all CO[sub 2] and N treatments at the final harvest. Thus biological differences between pine species seem to be small and N is not the environmental factormore » accounting for differences in CO[sub 2] responses observed at the 2 field sites. Small biological differences between Loblolly and Ponderosa pine may be difficult to detect in experiments with seedlings, but scale to important differences between species as trees mature or when forest stands are considered.« less


In CDMA system, co-channel interference (CCI) includes intracell multiple-access interference and intercell interference. In TD-SCDMA mobile systems, intracell MAI can be eliminated by joint detection. In this paper, one approach combined joint detector and spatial filter which can eliminate both intercell and intracell interference is proposed. Moreover, this approach can be implemented with low computational complexity. Link simulation shows that the performance of TD-SCDMA systems with this approach is better than joint detection with antenna diversity.


Abstract Molecular diagnosis, chemo-diagnosis and physiological parameter have been applied for detecting the Ganoderma disease of coconut. Polyclonal antibodies (PAbs) raised against mycelial protein of Ganoderma, specific mycelial protein (62 kDa) of Ganoderma isolates and basidiocarp protein of Ganoderma were used for detection. All the PAbs could detect Ganoderma in diseased coconut root tissues in early stage of the disease before symptom expression by indirect – ELISA at the antiserum dilution of 1:1000 for mycelial protein, 1:700 for specific protein and 1:3000 for basidiocarp protein. Low cross reactions were observed with saprophytic fungi occurring in coconut roots and also with other basidiomycetous fungi. For polymerase chain reaction tests, the primer was generated from the internal transcribed spacer region one (ITS 1) of rDNA of Ganoderma, which produced a PCR product of 167 bp in size. Utility of this method was confirmed at the field level.


Article IV Section 2 of the U.S. Constitution made fugitive slave legislation possible. The article provided for the capture and removal of fugitives from labor. The federal Fugitive Slave Law of 1793 enacted the clause when it approved the rendition of escaped slaves, and made it a crime to harbor or conceal alleged runaways.' The Fugitive Slave Law (FSL) went almost without notice for four decades. When the antislavery movement accelerated during the 1830s, its leaders condemned the law, claiming that it went beyond the scope intended by the framers. The Founding Fathers, they contended, recognized that this provision could only be implemented by individual states. Yet, Congress seized the opportunity in 1793 to legislate on slavery.2 In recent years, historians have also criticized the legislation. They claim its ambiguity influenced free states to implement the law. Northern states cooperated with slaveholders by providing for the employment of public officers to arrest and try runaway slaves. But there was nothing in the article which mandated this action. Thus, it is no wonder that this initiative brought on the wrath of abolitionists by the 1830s, especially those in southern Ohio.3 Cincinnati abolitionists James Gillespie Birney and Salmon Portland Chase led a cadre of attorneys who launched a legal assault on the FSL.4 These abolitionists continued their protest in ensuing years, and after September 18, 1850 when Congress adopted the second FSL, they voiced strong objections. The editors of the Dayton Evening Empire wrote: "There seems to be a determination in certain quarters to resist the operation of the law recently passed by Congress, for the apprehension of fugitive slaves and their restoration to their owners."5 The framers of the FSL had drafted the legislation to provide a more uniform method for the capture and removal of runaway slaves. Before 1850, antislavery litigation in the North had led to the creation of liberated zones, thereby weakening the first FSL. The second FSL was designed to overcome this deficiency by: 1) the appointment of federal marshals who would capture runaways; and 2) the installation of federal commissioners who would review claims for alleged slaves.


Compact polyelectrolyte complexes (COPECs), also named saloplastics, represent a new class of material with high fracture strain and self-healing properties. Here, COPECs based on poly(methacrylic acid) (PMAA) and poly(allylamine hydrochloride) (PAH) were prepared by centrifugation at pH 7. The influence of postassembly pH changes was monitored chemically by ATR-FTIR, ICP, DSC, and TGA, morphologically by SEM, and mechanically by strain to break measurements. Postassembly pH stimuli misbalanced the charge ratio in COPECs, impacting their concentration in counterions, cross-link density, and polymer chain mobility. At the material level, changes were observed in the porosity, composition, water content, and mechanical properties of COPECs. The cross-link density was a prominent factor governing the saloplastic's composition and water content. However, the porosity and mechanical properties were driven by several factors including salt-induced plasticization and conformational changes of polyelectrolytes. T...


Sustainable management with forest ecosystems is based on forest ecosystem stability, or their biological and ecological balance. Sustainable management aims to achieve optimal production in forest ecosystems, or in other words, long-term production of large amounts of high quality wood mass and other forest products, as well as long term fulfilment of other forest functions. In order to achieve these goals, it is necessary to maintain the optimal condition of trees, stands and the entire forest ecosystem. The natural balance of different forest ecosystem areas has recently been increasingly disturbed by numerous adverse impacts. Consequently, the stability and functioning of forest ecosystems, as well as their production and other functions, have been jeopardized. Expectedly, this exerts a negative effect on forest ecosystem management and requires that ecosystems adjust to changes. These changes include, for example, extensive tree damage, massive tree dieback, windthrow, pest attacks and others. The production and provision of different forest functions depend primarily on tree condition. Until recently, the condition of a tree was generally assessed on the basis of crown defoliation, changes in the tree crown colour and tree damage. However, since these indicators did not comprise all the indicators of tree condition that affect the production and provision of different functions, they were not sufficient to achieve an optimal wood mass production and deal with the disturbed stability of forest ecosystems. The paper proposes a model of tree vitality assessment based on morphological indicators of the tree condition. Trees with lessened vitality have a lessened ability to produce and provide varied forest functions, depending on the action of different factors on their development. To date, stand production in conditions of the disturbed stability and functioning of forest ecosystems has not been assessed on the basis of their vitality. Stand vitality represents the ability of a stand to optimally perform all life functions in a given site condition, including growth, development, propagation, resilience, adaptability, struggle for survival, longevity, and others. The attainment of life functions of forest trees and the achievement of an optimal production of forest stands depend on the biological balance in forest ecosystems and on the condition of a site. The vitality of forest ecosystems denotes the long-term ability of an ecosystem to realize the main life functions of an organism in a given site. These functions include growth, development, propagation, survival and stability. This is the reason that the assessment of forest ecosystem vitality takes into account the condition of organisms and the condition of ecological factors contributing to forest ecosystem production and the provision of other forest functions. Disturbances in the condition of organisms and the condition of sites in forest ecosystems lessen the vitality of these ecosystems. The paper analyzes past approaches to determining tree and forest vitality and proposes models of assessing tree, stand and ecosystem vitality for the needs of adaptive management of forest ecosystems.


The acute toxicities of 9 benzoic acids to Photobacterium phosphoreum were measured at pH 7.0. Quantitative structure-activity relationships (QSARs) were established using two physico-chemical parameters TSA and ELUMO, based on which the toxic mechanism of benzoic acid was preliminarily discussed. Results showed that the acute toxicities of benzoic acid varied with kind and position of substituents at the same pH. The toxic mechanism of benzoic acids to Photobacterium phosphoreum was mainly electrophilic and toxicities could be described by TSA in combination with ELUMO.


This investigation explores the processes of the identification of individuals used in science and adapts them to art photography. It analyses the data encoded in the body and develops the construction of photographic images through biometric principles in order to expand on current concepts of identity in contemporary art by digital and analogue processes.


* Abstract: TheHyphodontiaJ. Erikss. genus species are considered important degradation agents of wood, including the one used as building material. These species belong to the fungi which have the resupinate sporiferous body, sometimes covering large areas out of the building elements. They can be often found on the highly degraded wood area. In Romania, the signaling of the Hyphodontia J. Erikss . genus species in the open air museums of Moldavia, have been recently taken into consideration. In this paper there are presented two species identified in the BukovinaVillage Museum- Suceavaonwood buildings considered national patrimonyobjects.


Medicines play an important role in order to cure, prevent and diagnose human disease and keep people healthy. However, causing s ome quality defects or loss of effectiveness of the medicines surge into market wh ich not only badly put in danger the lives of the people, vibrate the strength of society, env ironment and cause the awful impact but also force to look the Reverse Logistics process, thus i t is necessary to recollect the unused medicines. The report discuss about the 5R Optimum Model (Reduce, Recycle, Reinforce, Report and Regulate) of the Pharmaceutical Reverse Logistics activity. As per the actual conditions Pharmaceutical recovery in our country, the collection center is assigned in some of the major places. Under our proposed model the r ecovery network would be flexible with the help of ERP system. "We have done an online survey in which we found that only 10% people want to purchase medicines before 15 days of expiry, because of this low percentage there is a huge disposal of medicine, and we can re duce this disposal by optimum use of


Biosurfactants are amphiphilic biological compounds produced extracellularly as a part of cell membranes by a variety of yeast, bacteria and filamentous fungi. Specifically, lipopeptide biosurfactant are produced by Bacillus subtilis species and are classified into three types: surfactin, iturin and fengycins. The biochemical mechanism for their biosynthesis depends upon non-ribosomal peptide synthetases. Particularly, surfactin synthesis is dependent upon surfactin synthetase operon which is regulated by complex cascade of reactions. Biosurfactants play an extravagant role and have varied industrial and environmental applications. This study focuses upon production of surfactin and to demonstrate its activity against bacteria and biofilm formation. Its use is also demonstrated in water purification stain removal.


A 2μm digital signal processor with a 125ns instruction cycle will be described. It contains two 16b data buses, executes a 40b orthogonal instruction set and supports up to six concurrent arithmetic and data-move operations in each instruction.


This study aims to investigate if and why business-to-consumer (B2C) video call services are diffusing across industry boundaries. Prior research has been conducted within the separate areas of video communication, diffusion of innovations, and cross-industry innovation. The study integrates these separate areas in order to explain the new phenomenon of organisations applying video calls to distribute services to consumers. Because diffusion theory is the core of the study, Rogers's Diffusion of Innovations model has steered the research process. A sample of eight case companies from various industries with different applications of B2C video call services was identified. The study's empirical findings supported the cross-industry diffusion of B2C video call services. Rogers's five attributes of innovations could partly explain the diffusion. The relative advantages, a rather high compatibility, moderate complexity, a high trialability, and a high degree of observability of B2C video call services have contributed to the diffusion. As Rogers's model does not provide sufficient explanatory value when taking an organisational perspective of diffusion research, additional literature and the empirical findings were applied to explain why diffusion has occurred. The identified drivers of diffusion can be categorized accordingly: (1) the benefit of being an imitating organisation, (2) the benefit of cross-industry innovation search within organisations, and (3) the strategic importance of being an innovative organisation.


TkiTUCH has been written on phenol XVL as a contaminant of water supplies. Regulations limi ing its concen tration or even prohibiting its discharge into water have been adopted by regula ry agencies. Techniques developed to destroy phenols have been integrat with eatm t plant op rations. The cost of research work on phenol as a n aminant has been enormous, a cost that can ot be expected to be spent n every other contaminant. And yet, with all the research, the role of phenol is uncertain. There is a definite lack of


We propose a cluster-based method to detect and locate eavesdropping events in optical line systems characterized by small power losses. Our findings indicate that detecting such subtle losses from eavesdropping can be accomplished solely through optical performance monitoring (OPM) data collected at the receiver. On the other hand, the localization of such events can be effectively achieved by leveraging in-line OPM data.


Provided is a graft copolymer which has excellent impact resistance-imparting effect, and which is capable of providing a thermoplastic resin composition that has excellent weather resistance and color developability. A graft copolymer (C) which is obtained by graft polymerizing one or more monomers (B), which are selected from among a (meth)acrylate, an aromatic vinyl, vinyl cyanide, an N-substituted maleimide and maleic acid, to a composite rubbery polymer (A) that is obtained by polymerizing a mixture (Ac) containing a polyorganosiloxane (Aa) and an acrylate (Ab) after the formation of a mini-emulsion in an aqueous solvent. A thermoplastic resin composition which contains this graft copolymer (C) and a thermoplastic resin (D).


Forecasting the crowd flows in a city is crucial for public safety, traffic management and urban planning. Researchers proposed several methods to forecast the crowd flows. However, they omitted the acquisition of comprehensive flow data. Taxis' GPS trajectory data and bike sharing system data are often used in these works as the flow data. But they are not able to reflect the comprehensive crowd flows in a city, since they only contain the transitions of a specific transportation mode. In this paper, we propose to extract comprehensive crowd flows from mobile flow records (MFRs), a finegrained cellular data. We also use a Convolution Neural Network (CNN) based method to forecast crowd flows and compare it with traditional time series regression models. The experiments on a large-scale cellular dataset show that CNN based method can reduce the error by 28% to 77%.


Introduction: The Identity of Japanese and German Civil Laws Zentaro Kitagawa Part 1: Foreign Influences on Japanese Civil Law Japanese Civil Law and German Law - From the Viewpoint of Comparative Law Zentaro Kitagawa Modernization of German Civil Law and Japanese Civil Law Interpretation Yoshio Shiomi French Law Research in the Study of Civil Law in Japan Taro Kogayu Anglo-American Law Research in the Study of Civil Law in Japan Tsuneo Matsumoto Part 2: The Identity of Japanese and German Civil Law Deutsches Burgerliches Recht und Europaisches Zivilrecht in Gegenwart und Zukunft Dieter Leipold English Summary Karl Riesenhuber The Present and Future Role of the German Civil Law in Europe Stephan Lorenz On the Identity of Japanese Civil Law from a European View Karl Riesenhuber On the Identity of Japanese Civil Law from Common Law Perspectives Malcolm Smith.


Annual Leave Central Scheme Guidelines provide all member agencies with an overview of the operations of the Annual Leave Central Scheme, including the establishment and ongoing operations of the scheme.


. Research related to ergonomic evaluation of acoustic environment in PCPW EKO-KARPATY in Tarnowiec during production of agricultural anti-weed fabric. The scope of the paper included noise measurement and spectrum analysis at particular unassisted work stations of the process line. The conducted analysis indicated that applicable standards were exceeded in all cases and that there was justified fear that conversion of spaces designed for agricultural production for industrial applications will have a negative impact on health of people working in these conditions. Some suggestions were developed regarding modifications that will ensure conformity with the applicable standards regarding noise level.


When designing a perishable goods supply chain network under trade credit arrangements, distribution companies must contend with deteriorating inventory and product preservation efforts to maximise profits. Key decisions include locating distribution centres (DCs), assigning retail stores to DCs, joint replenishment cycle time and investing in preservation technology. This paper addresses these factors from the position that as preservation effort increases, preservation technology cost increases and deterioration rate decreases. An algorithm based on piecewise nonlinear optimisation is provided for solving supply chain network design problems efficiently. In contrast to other studies that have used the approximation approach, the proposed approach solves the original problem accurately and efficiently. Numerical studies are conducted to demonstrate the solutions procedures and determine the effects of the parameters on decisions and profits. The results of this study and the proposed modelling approach are useful references for managerial decisions in designing a supply chain network the context of trade credit and inventory deterioration.


408Background: To assess GD or FCT as the chemoradiation (CRT) component of a bladder sparing regimen. Methods: Patients with T2-4a bladder cancer were randomized. Patients had a maximal transurethral resection and induction CRT to 40 Gy followed by cystoscopic assessment. Patients with a complete response (CR) received consolidation CRT to 64 Gy. Others were offered cystectomy and no further CRT. Adjuvant gemcitabine/cisplatin chemotherapy was subsequently administered. The primary endpoint was the rate of distant metastasis at 3 years (DM3). Toxicity and other efficacy related endpoints including CR and bladder intact distant metastasis free survival at 3 years (BI-DMFS3) were also assessed. Using the Clopper-Pearson method, the study required 32 patients per arm, with a benchmark DM3 of 25% and a 1-sided significance level of 0.1. If both arms meet this benchmark, toxicity will be used to select a regimen for future study. This study was not designed to compare arms. Results: From 12/2008 to 4/2014, 70...


Kidney stone disease is a result of combination of food items consuming, drinking water quality and genetic heritability, which has been observed to be more prone (both occurrence and recurrence) to certain geographic regimes as Thanjavur suburbs of Tamil Nadu in southern India. The
 research carried out involves collection of medical information of Kidneystone patients of the study area and survey of their dietary habits including drinking water quality (through laboratory study), selection of suitable classifier to model the Kidney stone recurrence with the most contributing
 of 22 parameters (with due model evaluation). Weka (3.8.1) machine learning framework was used for the study, for evaluating the model accuracy of 66 classifiers, resulting 22 classifiers with accuracy higher than ZeroR, which was considered to be the benchmark. Based on this study, C-4.5
 classifier (called J48 in Weka) was found to be most robust classifier, based on accuracy, precision, Recall, F-Measure, MCC, ROC Area and PRC Area. The selected classifiers were again evaluated based on domain conformance (namely, literature, logic and consistency) to obtain four validated
 classifiers, thereby providing seven parameters and their threshold value for kidney stone recurrence, namely, family history (Yes), Sulphate (>17ppm), potassium (>74 ppm), nitrate (>1.2 ppm), salinity (>120 ppm), conductivity (<=289 ppm) and water consumption (moderate).


Modelling of hydrodynamic and morphological processes in estuaries is very important in coastal research. The development of sophisticated numerical models requires appropriate theoretical models which can accurately describe physical processes in coastal areas. However, the existing morphological models always have over-simplified assumptions in physics, for example, the constant bed roughness, which usually leads to wrong predictions in sediment flux. For this reason, a physics-based bed roughness model is developed by Toorman (2012) as a general approach to improve the predictive accuracy of morphological models.


The basic results of a new theory of regular functions of a quaternionic variable have been recently stated, following an idea of Cullen. In this paper we prove the minimum modulus principle and the open mapping theorem for regular functions. The proofs involve some peculiar geometric properties of such functions which are of independent interest.


We consider how processes of dynamical, multiple, overlapping, interfering, correlated interactions establishing collective systems are analytically intractable. The metastructures project has the purpose of using mesoscopic (rather than macroscopic or statistical) representations to allow interventions which can suitably modify various properties acquired by emergent collective behaviours. We consider mesoscopic variables and mesoscopic properties as suitable for representing such systems of interactions. Properties of collective systems, such as coherence(s), are considered to be suitably represented by mesoscopic dynamics. Finally, mesoscopic interventions are considered as suitable for acting upon collective systems.


Objectives: Variation in biochemical constituents such as protein, glucose, cholesterol, acid phosphatase and alkaline phosphatase present in the haemolymph of Portunus pelagicus [Blue Swimming Crab] at different reproductive stages was studied. Methods: Haemolymphs were collected from different reproductive groups by cutting the walking legs using hypodermic syringe with No. 22 needle after rinsing with modified citrate EDTA buffer and estimated standard methodology. Results: The protein content in the haemolymph it gradually increased from immature to ripe stage [3.4±0.49-5.5±0.74 gm/DL] with minimum at immature stage and maximum in ripe stage. Glucose content was maximum in immature stage [49.5±1.28 mg/DL] and minimum in ripe stage [35.4±1.23 mg/DL]. The cholesterol was showed that maximum value in ripe stage [98.0±1.81 mg/DL] and minimum in immature stage [79.0±1.54 mg/DL]. The synthesized enzyme, acid phosphatase was minimum in spent [2.5±0.24 IU/L] and maximum in maturing stage [3.1±0.23 IU/L]. Meanwhile, alkaline phosphatase ranged from 91.0±1.62 to 138±1.79 IU/L with minimum in spent and maximum in immature stage. It indicates that the biochemical components and enzymes are actively participated in gametogenesis. Conclusion: This study inferred that breeding of P. pelagicus mainly depends on nutritive condition and reserved organic constituents of the blood.


Neural networks are becoming an attractive solution for automatizing vehicles in the automotive, military, and aerospace markets. Thanks to their low-cost, low-power consumption, and flexibility, field-programmable gate arrays (FPGAs) are among the promising devices to implement neural networks. Unfortunately, FPGAs are also known to be susceptible to radiation-induced errors. In this paper, we evaluate the effects of radiation-induced errors in the output correctness of two neural networks [Iris Flower artificial neural network (ANN) and Modified National Institute of Standards and Technology (MNIST) convolutional neural network (CNN)] implemented in static random-access memory-based FPGAs. In particular, we notice that radiation can induce errors that modify the output of the network with or without affecting the neural network's functionality. We call the former critical errors and the latter tolerable errors. Through exhaustive fault injection, we identify the portions of Iris Flower ANN and MNIST CNN implementation on FPGAs that are more likely, once corrupted, to generate a critical or a tolerable error. Based on this analysis, we propose a selective hardening strategy that triplicates only the most vulnerable layers of the neural network. With neutron radiation testing, our selective hardening solution was able to mask 40% of faults with a marginal 8% overhead in one of our tested neural networks.


Volumetric determination of mesoxalic acid by phenylhydrazine method1 and the microdetermination of mesoxalic acid and related compounds have been reported2. Jwo and Noyes3 reported the quantitative oxidation of mesoxalic acid to carbon dioxide and water in the presence of excess of cerium(IV). These methods are cumbersome and time-consuming. The authors now report the reaction between mesoxalic acid and thallium( ill) and describe convenient titrimetric and spectrophotometric methods for the determination of mesoxalic acid in mmol and u mol ranges respectively.


This is the text of Catherine Middleton's Big Thinking Lecture to Canada's Federal parliamentarians. See http://www.fedcan.ca/content/en/323/Big_Thinking.html for details of this event.


10 www.ijerm.com  Abstract—Waste ripe plantain peels and groundnut shell constitute environmental pollution in the Niger Delta Area of Nigeria where it is not properly disposed. These wastes can be converted into useful products such as pozzolans as replacement for cement in Sandcrete block production, thus helping to conserve the environment and preserve the earth crust. This research work is aimed at determining if the compressive strength of blocks made from replacement of cement with these pozzolans obtained from waste ripe plantain peel ash and dry groundnut shell ash and their blends would meet regulatory standard for use as partial replacement for cement. The results obtained from the experiments carried showed that Plantain peel ash (PPA) and groundnut shell ash(GSA) contains cementitious properties and can be used as replacement for cement in sandcrete. The compressive strength of blocks produced decreases with increasing percentage replacement of the waste ash with cement. Sandcrete blocks made with plantain peel ash cannot be used in areas with lots of water because of the water absorption properties of plantain peel ash and the ternary blend (GSA/PPA) of the ashes proves to have greater compressive strength than individual binary mixture PPA and GSA respectively. The cement replacement by these pozzolans is best achieved at replacement up to 10% ash.


Colleges employment forecasting based on least squares support vector machine is proposed in the paper. Least squares support vector machine is an improved support vector machine, which can use equality constraints for the error instead of inequality constraints. Colleges employment rate of Xinjiang agricultural university from 1997 to 2006 is used to show the effectiveness of least squares support vector machine.The comparison results of forecasting error for colleges employment rate between least squares support vector machine and BP neural network indicate that least squares support vector machine has a higher forecasting accuracy than BP neural network.


Abstract When planning for ship navigation or compiling data for a bathymetry map, the navigator or mapper uses many different sources of bathymetry information and navigation hazards. The quality of these sources is inconsistent in general, however, making it challenging to provide a coherent picture for planning. Here, we describe an approach for consistent planning/mapping that uses a combination of soft computing and Bayesian estimation. The case study used to exercise this system involves NOAA Electronic Nautical Charts for an area in the Chesapeake Bay. We first interpolate each set of irregularly spaced soundings to gridded versions of each point-cloud set. Each of these intermediate grids is then aggregated into a fused bathymetric realization using order weighted averaging (OWA) to provide the weights for each source based on their subjective reliabilities. The OWA allows for fusion informed by the user's subjective risk allowed in the reconstruction of the seafloor surface and provides quantitative methods to generate, use, and record subjective reliability weights. Each sounding point that went into the bathymetry estimate is then categorized as "no-go," "caution," or "go" status. Reliability estimates are reused for weighted Bayesian categorization of each output grid cell to compute the navigable surface.


On 9th April 2015, Allwork gave a talk at NN Gallery, Northampton in response to Pam Foley's exhibition, 'Routes of Sorrow'. This talk was recorded and can be accessed through Pam Foley's website and You Tube.


To the Editor.— We of the Southern California Permanente Medical Group were flattered by the favorable comments expressed by Dr Amador regarding our centralized laboratory operation in his article "Shared Clinical Laboratories" (236:1162, 1976). We feel, however, that a few inaccuracies should be corrected in an otherwise excellent, thought-provoking article. The statement "significant defects in the Permanente Systems are the absence of teaching programs for residents and student technologists and the total absence of research" is incorrect. For many years we have had an approved, four-year residency program in pathology. For more than 20 years we have had a California State Department of Public Health approved school of medical technology and have prepared for licensure 10 to 12 students per year. The quality of our teaching program is second to none in the area. Moreover, we have a regularly scheduled, in-house educational program, on company time, for all personnel, and we


Armstrong, P., Armstrong, H., Choiniere, J., Lowndes, R. and Struthers, J. (2020) Re-Imagining Long-Term Residential Care in the COVID-19 Crisis, Ottawa: Canadian Centre for Policy Alternatives. Baines, D., Dulhunty, A. and Charlesworth, S. (2021) 'Relationship-based care work, austerity and aged care', Work, Employment and Society, DOI: 10.1177/0950017020980985. Bartha, A. and Zentai, V. (2020) 'Long-term care and gender equality: fuzzy-set ideal types of care regimes in Europe', Social Inclusion, 8, 4, 92–102. Béland, D. and Marier, P. (2020) 'COVID-19 and long-term care policy for older people in Canada', Journal of Aging and Social Policy, 32, 4–5, 358-364. Bethell, J., Aelick, K., Babineau, J., Bretzlaff, M., Edwards, C., Gibson, J. L., Hewitt Colborne, D., Iaboni, A., Lender, D., Schon, D. and McGilton, K. (2020) 'Social connection in long-term care homes: a scoping review of published research on the mental health impacts and potential strategies during COVID-19', Journal of the American Medical Directors Association, 22, 2, 228–237. Charlesworth, S. and Isherwood, L. (2020) 'Migrant aged-care workers in Australia: do they have poorerquality jobs than their locally born counterparts?', Ageing and Society, DOI: 10.1017/ S0144686X20000525, 1–21. Chau, H. S. and Schwiter, K. (2021) 'Who shapes migration in open labour markets? Analysing migration infrastructures and brokers of circularly migrating home care workers in Switzerland,Mobilities, DOI: doi.org/10.1080/17450101.2021.1971052 Ciccia, R. and Lombardo, E. (2019) 'Care policies in practice: how discourse matters for policy implementation', Policy and Society, 38, 4, 537–553. Dyer, S. M., Valeri, M., Arora, N., Ross, T., Winsall, M., Tilden, D. and Crotty, M. (2019) Review of International Systems for Long-Term Care of Older People, Adelaide, Australia: Flinders University. Fischer, B., Peine, A. and Östlund, B. (2020) 'The importance of user involvement: a systematic review of involving older users in technology design', The Gerontologist, 60, 7, e513–e523. Frazer, K., Mitchell, L., Stokes, D., Lacey, E., Crowley, E. and Kelleher, C. C. (2021) 'A rapid systematic review of measures to protect older people in long-term care facilities from COVID-19', BMJ Open, 11, 10, e047012. Ilinca, S., Rodrigues, R. and Schmidt, A. E. (2017) 'Fairness and eligibility to long-term care: an analysis of the factors driving inequality and inequity in the use of home care for older Europeans', International Journal of Environmental Research and Public Health, 14, 10, 1224. International Long-Term Care Policy Network (N.D.) International Reports on COVID-19 and Long-Term Care, https://ltccovid.org/international-reports-on-covid-19-and-long-term-care/ [accessed 23.09.2021]. King-Dejardin, A. (2019) The Social Construction of Migrant Care Work. At the Intersection of Care, Migration and Gender, Geneva: International Labour Office. Social Policy & Society (2022) 21:2, 331–332 © The Author(s), 2022. Published by Cambridge University Press. doi:10.1017/S1474746421000920


Globally the interest of large-scale structure has been increasing for the use in various social and cultural events. However various problems for building large-scale structure in South Korea are expected in terms of construction method and site management due to the lack of experience. Construction method and planning significantly affects on making decisions. There are only theoretical approach for constructing large-scale building in domestic with the limited experience of constructing constrained size structure. Through Analytic Hierarchy Process with experts, derived decision factors mostly used construction method in construction of large-scale structure. Derived factors from this study will support making decisions for field management in constructing large-scale structure.


Interactions between a biomaterial implanted in bone and the surrounding bone tissue are dependent on the surface characteristics of the implant. Surface characteristics that promote osteointegration, formation of a direct interface between an implant and bone leading to superior implant fixation, are desirable. Improvement of the attachment, proliferation and differentiation of bone-forming cells are a pre-requisite for formation of new bone tissue, hence surface characteristics which promote these are desirable. Collagen is a fibrillar structural protein in mammalian tissues and chitosan is a polysaccharide derived from marine invertebrate exoskeletons. Both promote cell attachment, proliferation and differentiation, and thus both are suitable as implant coating materials. In this study, collagen-chitosan coatings were formed and their mechanical properties were studied. To our best knowledge, the combination of collagen and chitosan in such coatings is novel. The influence of chitosan on the morphology and the Young's modulus of collagen-chitosan coatings was investigated. Two different approaches for the formation of the collagen-chitosan coatings were compared. In the first approach, hydrogel formation took place directly on the substrate, and fibrils formed directly on the surface. In the second approach, collagen and chitosan were adsorbed from preformed hydrogels. Larger fibrils were observed through the first approach, while many small fibrils were observed through the second approach. The highest Young's modulus was observed for collagen coatings containing 0.75-1.5% chitosan. This was true for both approaches, but a higher Young's modulus was obtained through the first approach. The elastic behavior of collagen-chitosan hydrogels was determined using rheometry, to obtain a deeper understanding of the collagen-chitosan interactions that might influence the adsorbed coatings. The gelation process occurred more slowly for hydrogels containing a higher chitosan concentration. It appeared that the storage modulus was higher for chitosan concentrations of 3-6% in the collagen-chitosan hydrogels. These results pave the way for cell biological characterization of the coatings and may assist in the interpretation of the results.


An assessment is made of the accuracy and suitability of the three-dimensional full potential and Euler equations in the modeling of subcritical and supercritical rotor blade-vortex interactions (BVI). The interaction velocity fields are obtained through a nonlinear superposition of the rotor and the vortex wake flow fields. Vortex effects are simulated using the velocity 'transpiration' approach. A modified surface condition is prescribed and enforced at each time step of the computations to satisfy the tangency boundary condition. Potential blade-vortex encounters are identified and tracked in time at equal increments of rotor azimuth using the lifting-line helicopter/rotor trim code CAMRAD. This information is then utilized in interpolation routines within the flow solvers to compute the instantaneous position(s) of the interaction vortex element(s) with respect to the blade for the time-accurate calculations. Results for subcritical self-generated BVI and for supercritical interactions resulting from an upstream-generated vortex are presented.


Oil-cooled generators for aircraft were first developed in Britain about nine years ago, and, for the first seven years, attention was focused on indirectly liquid-cooled machines, in which the coolant was confined within oil galleries during its route through the machine. More recently, directly liquid-cooled machines have been developed in which the cooling oil is sprayed within the generator directly on to the rotor and stator windings and other components to be cooled. Large savings in weight are possible by using direct liquid cooling because of the improved heat transfer and the consequent reduction in active material (iron and copper).


Objective To investigate the breeding characteristics of Aedes albopictus in urbanization residential area,which should provide the basis for the control of Ae.albopictus. Methods The study was carried out in the village of Jieyang city and high-urbanization downtown of Foshan from March 2004 to November 2005. Water containers were detected in and around one household which was randomly selected every 5 households. The data were analyzed by software SPSS 11.0. Results Of 5635 possible breeding sites in 7470 houses investigated, 502(6.72%) were positive. In the village of Jieyang,the major breeding containers included unused container (jars, bottles and tins, etc.) and water reservoir receptacles with the positive constitute ratio of 64.98% and 18.77% respectively. The positive constitute ratio of unused containers reached the maximum in September every year. But in residential area of Foshan city, the major breeding containers were made up of water vases in which the flowers and plants grow and unused containera, and the positive constitute ratio of them were 45.52% and 33.79% respectively. The positive constitute ratio of unused containers was in the peak from July to September, and that in miniascape and water plant was the highest in 2004 and May 2005 with the value of 75.00%. But the result was zero after May 2005. Conclusion There were different among the breeding sites in different residential area, which varied with season. The breeding containers in increasing urbanization cities were mainly miniascape, water plant and unused containers, but in low urbanization village, the breeding sites were mainly the unused containers and water reservoir receptacle.


Objective: To examine the efficacy and safety of acupuncture therapy for depressive and anxious symptoms of outpatients receiving methadone maintenance treatment(MMT).Methods: By using randomized double-blinded controlled design,eighty-nine MMT outpatients with obvious depressive and anxious symptoms,were randomly assigned to acupuncture group(n=48) and placebo-acupuncture group(n=41).All patients continued their previous MMT schemes.In acupuncture group,acupuncture was applied to Neiguan,Hegu,Zusanli,Sanyinjiao,etc.In placebo-acupuncture group,acupuncture was applied to non-acupoint spots(5 mm lateral to the acupoints selected in acupuncture group) with shallow needling technique.The treatment lasted for 8 weeks,5 sessions per week.For efficacy assessment,patients were administered SAS and SDS at baseline and every two-week interval.Adverse event rates were compared between two groups to assess the safety.Results: Repeated measurement variance analysis revealed that the overall SDS and SAS reduction of acupuncture group was significantly higher than placebo-acupuncture group(F=5.99,P=0.005;F=8.36,P0.001).The adverse event rates of acupuncture were 8.33%(4/48) and 9.76%(4/41) for acupuncture group and placebo-acupuncture group,their difference was not statistically significant(x2=0.055,P=0.815).Conclusion: Acupuncture therapy can effectively and safely improve the depressive and anxious symptoms of outpatients receiving MMT.


Urotensin-II (U-II) has been shown to be the most potent mammalian vasoconstrictor known. [1, 2] Thus a U-II antagonist might be of therapeutic value in a number of cardiovascular disorders. [3] However, interspecies variability of several nonpeptidic ligands complicates the interpretation of in vivo studies of such antagonists in pre-clinical animal models of disease. Thus compound ACT058362 is a selective antagonist for human U-II receptor (hUT2R) with a reported K d ~ 4 nM in a molecular binding assay, but it is reported to bind weakly to rat UT2R (rUT2R), with K d ~ 1,500 nM. [4] In contrast, the arylsulphonamide SB706375 is a selective antagonist against both hUT2R (K d : ~ 9 nM) and rUT2R (K d : ~ 21 nM). [3] To understand the species selectivity of the UT2R, we investigated the binding site of ACT058362 and SB706375 complex with both hUT2R and rUT2R to explain the dramatic (~ 400-fold) lower affinity of ACT058362 for rUT2R and the similar (~10 nM) affinity of SB706375 for both UT2R. These studies.used MembStruk and MSCDock to predict the UT2R structure and the binding site for ACT058362 and SB706375. Based on binding energy, we found two binding modes each with D130 3.32 as the crucial anchoring point. We predict that ACT058362 (an aryl-amine-aryl or ANA ligand) binds in the TM 3456 region while we predict that SB706375 (an aryl-aryl-amine or AAN ligand) binds in the TM 1237 region. These predicted sites explain the known differences in binding the ANA ligand to rat and human while explaining the similar binding of the AAN compound to rat and human. Moreover the predictions explain currently available SAR data. To further validate the predicted binding site of these ligands to hUT2R and rUT2R, we propose several mutations that would help define the structural origins of differential responses of UT2R among species potentially indicating novel UT2R antagonists with cross-species high affinity.


Aims & objective: This study was designed with a view to find out the cytological mechanism of this type of pathologic keratinisation Material and method: 34 patients with hyperkeratotic lesion were included. All the lesions were biopised and compare clinical and histologic diagnosis along with that slideds were stained with H.& E. stain, Modofied Mallory stain, Tolludine blue and P.A.S. stain with Diastase digestion with hematoxylin counter stain to evaluate keratinisation, keratohyaline granules and thickness of granular layer. Conclusions: white lesions having a deposition of keratin were included irrespective of clinical or histologic diagnosis because the idea was to observe the structural changes in epithelium which lead a nonkeratinised mucous membrane to become pathologically keratinsed


The article describes hospitalityindustry in Galicia during the interwaryears. The First World War caused thedecline of hospitality industry. Its revivalbegan only in the 1920s, and reached itspeak in the middle of the1930s. It has beenestablished that there were 384 hotelswith almost 13.500 rooms in Polandduring the interwar years. 195 hotels weresituated in 45 towns of Galicia. Theyincluded 4605 rooms for 7625 guests. Thelargest number of places to stay werelocated in Zakopane, Krynycia, Krakow,Rabets, Truskavets, Lviv and Szczawnica.Hotels with the largest room numberand the biggest capacity were located inZakopane, Krakow and Krynycia. Thehotels «Lazenky» (Krynycia), «Polonia»(Krynycia) and «George» (Lviv) had thelargest room number. The hotels«Lazenky» (Krynycia), «Polonia» (Krakow), «Charlton» (Krynycia), «George»(Lviv) and the Officers' Recreation House(Krynycia) had the biggest capacity.Only 10 hotels had single rooms withbath, 147 hotels had single rooms withoutbath, and 48 hotels didn't have any singlerooms at all. 10 hotels had double roomswith bath, 145 hotels had double roomswithout bath, 50 hotels didn't have anydouble rooms.Hotel room prices ranged from zl 3 tozl 18,5. Almost 50 percent of hotelsprovided services on therapeutic tubtreatment that cost from zl 0,5 to zl 3,5.Every third hotel had a garage.An average price of a single room withbath, maintenance, therapeutic tub andgarage was zl 16 a day. An average priceof a single room without bath, but withmaintenance, therapeutic tub and garagewas zl 9,5 a day. An average price of adouble room with bath, maintenance,therapeutic tub and garage was zl 24 aday. An average price of a double roomwithout bath, but with maintenance, therapeutictub and garage was zl 12 a day.


We report a crypto-display metasurface fabricated by laser splashed 3D nanostructures. Splashing morphologies that scatter angle-sensitive colors are realized through irradiation of a single femtosecond pulse onto titanium film. Angularly-anisotropic color image encryption are demonstrated.


Abstract : The International Criminal Court ("ICC") is widely regarded within the international community as a positive and necessary step toward individual accountability for those who order and carry out the most heinous of crimes genocide, crimes against humanity, and war crimes. The United States government views the ICC as an international institution that threatens U.S. sovereignty and has the potential to be a forum in which its servicemembers and government officials may fall victim to malicious, politically motivated prosecutions. Congress and the Bush administration instituted measures to minimize the possibility of American citizens falling under ICC jurisdiction. These measures accomplished little in terms of true protection of U.S. citizens from ICC prosecution; they did, however, adversely impact U.S. strategic interests. This paper will examine the ICC's authority, U.S. objections to ICC authority, U.S. actions to prevent the ICC from obtaining jurisdiction over American citizens and the adverse impact these actions had on its strategic interests, and offer a less contentious approach for dealing with both the ICC and other nations that support the Court.


The characteristics of the fiber reinforced plastic (FRP) and concrete bonded interface directly decided the results of structural reinforcement. The shear test was well simulated, and the shear stress distribution along the bonded interface was obtained by using 2D and 3D finite element method. The parametric study of influential factors (e.g., Young's moduli, shear moduli, and thickness, etc) on shear stress of the FRPconcrete bonded interface was discussed, and the influence of stress concentration on the interfacial shear stress distribution characteristics was gained. The results are very useful for designing the shear-resisting bonding strength test as well as characterizing the FRP-strengthened concrete bonded interface. Keywords-FRP; concrete; bonded interface, shear stress, parametric study.


We present the results of the first Dalitz plot analysis of the decay $D^{0}\to K^{-}\pi^{+}\eta$. The analysis is performed on a data set corresponding to an integrated luminosity of 953 $\rm{fb}^{-1}$ collected by the Belle detector at the asymmetric-energy $e^{+}e^{-}$ KEKB collider. The Dalitz plot is well described by a combination of the six resonant decay channels $\bar{K}^{*}(892)^0\eta$, $K^{-}a_0(980)^+$, $K^{-}a_2(1320)^+$, $\bar{K}^{*}(1410)^0\eta$, $K^{*}(1680)^-\pi^{+}$ and $K_2^{*}(1980)^-\pi^{+}$, together with $K\pi$ and $K\eta$ S-wave components. The decays $K^{*}(1680)^{-}\to K^{-}\eta$ and $K_{2}^{*}(1980)^{-}\to K^{-}\eta$ are observed for the first time. We measure ratio of the branching fractions, $\frac{\mathcal{B}(D^{0}\to K^{-}\pi^{+}\eta)}{\mathcal{B}(D^{0}\to K^{-}\pi^{+})}=0.500\pm0.002{\rm(stat)}\pm0.020{\rm(syst)}\pm0.003{\rm (\mathcal{B}_{PDG})}$. Using the Dalitz fit result, the ratio $\frac{\mathcal{B}(K^{*}(1680)\to K\eta)}{\mathcal{B}(K^{*}(1680)\to K\pi)}$ is measured to be $0.11\pm0.02{\rm(stat)}^{+0.06}_{-0.04}{\rm(syst)}\pm0.04{\rm(\mathcal{B}_{\text{PDG}})}$; this is much lower than the theoretical expectations ($\approx1$) made under the assumption that $K^{*}(1680)$ is a pure $1^{3}D_1$ state. The product branching fraction $\mathcal{B}(D^0\to [K_2^{*}(1980)^-\to K^{-}\eta]\pi^{+})=(2.2^{+1.7}_{-1.9})\times10^{-4}$ is determined. In addition, the $\pi\eta^{\prime}$ contribution to the $a_0(980)^{\pm}$ resonance shape is confirmed with 10.1$\sigma$ statistical significance using the three-channel Flatte model. We also measure $\mathcal{B}(D^0\to\bar{K}^{*}(892)^0\eta)=(1.41^{+0.13}_{-0.12})\%$. This is consistent with, and more precise than, the current world average $(1.02\pm0.30)\%$, deviates with a significance of more than $3\sigma$ from the theoretical predictions of (0.51-0.92)%.


Increase in renewable energy penetration, in the recent past, has been one of the primary causes for serious issues in power quality of the utility grid. This has ushered in the need for a robust and stable control system for reference tracking and disturbance rejection of grid-connected converters. Conventionally, due to its simplicity and ability to achieve zero steady-state error, a simple proportional integral (PI) controller is used in the synchronous reference frame ($dq$) for current control of voltage-source based grid-connected systems. However, the PI controller by itself, may not suffice for adequate disturbance rejection, especially when the utility grid voltages contain other harmonics in addition to the fundamental component. This paper introduces and analyzes a dual-loop current control structure, which utilizes two independent controllers, one for reference tracking and the other for disturbance rejection in the $dq$ frame. A small signal model of the dual-loop current control has been presented and its robustness under grid impedance variation, examined. Extensive experimental results are presented to validate the dual-loop control strategy for improved disturbance rejection capability and filtering action during the presence of grid voltage disturbances and grid impedance variations, without compromising the reference tracking performance.


The present essay discusses the political and economical changes that served as a base for the setting of a new cycle of power in Ceara. It also considerate the extent of the rupture in traditional political practices that occurred after the emergence of the "new businessmen" in the eighties.


I derive a generalized version of the fundamental law of active management under some weak conditions. I show that the original fundamental law of Grinold and various extensions are special cases of the result presented in this paper. I also show that cross-sectional ICs are usually different from time series ICs even if the time series ICs are all the same across securities. The fundamental law derived in this paper is robust to forecast model specification. My results show that average signal IC and IC standard deviation are the two most important variables in determining the potential IR a strategy can achieve. I extend the fundamental law to models with multiple factors and study the impact of missing one or more return or risk factors to portfolio IR.


The invention relates to a surgical shaft-type instrument (1) comprising a shaft (2), at the distal end of which a jaw device (3) having branches (5) is arranged, at least one of which is movably mounted. At the proximal end of said jaw device, a handling device (4) is arranged, of which at least one grip part (6) for operating the jaw device (3) is movable. A transfer bar (7) is provided, which is coupled, at the distal end thereof, to the jaw device (3) and, at the proximal end thereof, to the handling system (4), and which comprises a tensile element (11) and a tubular pressure element (12). The two elements (11, 12) are connected to one another at the ends thereof, and one of the two elements (11, 12) is made of a highly flexible alloy. The invention is characterized in that the pressure element (12) is made of the highly flexible alloy, and in that the tensile element (11) is rope or wire and is made of a material that is not highly flexible.


A novel dual-output six-switch inverter topology is proposed in this study for independently supplying two three-phase loads. This inverter employs less number of semiconductor devices compared with former dual-output inverters proposed so far in the literature. Reducing the number of switches and hence drive and control circuits may result in a reduction in overall cost of the system, may reduce its semiconductor power loss and as a result increases efficiency and reliability especially in applications with low and medium voltage and power ratings. The new configuration is introduced and carrier-based pulse-width modulation (PWM) schemes for its two defined modes of operation (constant frequency and variable frequency modes) are developed. Analysis of sizing of the DC-link capacitors is also performed so as to minimise the DC-link voltage ripple and to reduce the value of DC-link capacitors. Furthermore, loss profile of the system is studied and the results are compared with counterpart topologies. Simulation and experimental results are presented to verify the authenticity of the theoretical model.


Dasui,the name of the water god,written in the bambooslips unearthed in Chu Tombs of Warring States is the name of god of the Yangtze River,not Tianrui,the Milk river,Shendao or the Huai river.


Instruction fetch mechanism is a performance bottleneck of a Superscalar Processor. The fetch performance of the processor can be improved with the aid of an instruction memory structure known as Trace Cache. This paper presents parameters and analytical expressions, which describe instruction fetch performance of a Trace Cache microarchitecture. The instruction fetch rates predicted by the expressions differ by seven percent from the simulated fetch rates for SPEC2000 benchmark programs. Presented analytical expressions are implemented in a computer program named Tulip. Tulip is used to explore parameters, and their influence on fetch performance. Tulip is also used to understand Trace Cache performance tradeoffs.


The volume coherent deflection of high-energy positive and negative particles in uniformly bent crystals is studied. The general analysis of potential scattering shows that the standard screening potential for a large class of collisions can cause the volume refraction for negative particles (antiprotons, electrons) instead of the volume reflection for positive particles (proton, positrons).


The difference in the properties of coal types from the Donets and Karaganda coalfields required special investigations of their interaction during coking. We coked mixtures of these coal types in a 200 kg oven, blending 10 charge variants so as to determine the effect of replacement of Donets type K and OS coal with type K Karaganda coal, which has similar properties, on the quality of the coke.


By studying the clinical and experimental researches about massage and body immunity at home and abroad in the recent ten years,this paper shows the clinical value in enhancing immunity and advocates spreading this special therapy.We need to collect clinical cases and do retrospective study to find out the law,and then go in for further experiment study,do comprehensive testing and summary and raise them to theory to direct clinical treatment.


hours of work, lower wage rates, early retirement and disability transfer programs. Approximately 14 percent of working age individuals report they have a health problem which restricts their activity [34]. While a number of studies exist documenting the relationship between health and labor market activity, most of the evidence specifically examining the association between poor health and labor force participation is derived from cross-sectional analyses. Furthermore, the majority of these studies consider the impact of poor health in general as opposed to specific chronic health conditions.' Thus, while the accumulated evidence clearly indicates that poor health has significant negative effects on labor force participation, these findings are limited because they do not consider the influence of chronic disease on work behavior over the life cycle.2 The purpose of this paper is to explore the effect of the onset of a chronic disease-arthritis -on work behavior over life cycle. Arthritis is an excellent health condition to study in this context for at least two reasons. First, while arthritis is a painful and crippling disease, it is rarely lifethreatening.3 Thus, the major impact of this disease is reflected by the influence it has on the capacity to work. Second, arthritis is the most common chronic disease and second leading cause of work disability in the United States [11]. In fact, the Arthritis Foundation reports that more than 40 million Americans or one in seven persons have some form of this disease. The econometric technique used here-a dynamic hazard model-is the appropriate methodology to examine the health-work relationship over the life cycle because this approach estimates the pattern of labor force behavior after disease onset. Since the results indicate the duration of


This document discusses on the analysis of the most suitable equipment for performing
an earth-moving from mass through a specialized program AutoCAD Civil 3D diagram. In
the case of the movement of Earth, machines are detailed so that the focus of this function
is only apiade to the type of material involved, designating the restrictions and
characteristics that affect the choice of it, depending on the properties of the soil where it
is going to work. Then, shows the most recurrent mode of calculation of unit costs for
earthmoving, discovering other cases and ways to tackle these estimates, so how also
determine volume of cut and fill, scree, scree slopes and performance of the machines.
In addition, joining, in each case, other options and conditions affecting the final price,
presenting the correct application of the factors studied.


The 1,3,4-trisubstituted pyrazoles are important compounds in the preparation of 15diphenylpyrazole non-nucleoside derivatives, which are used as HIV1 non-nucleoside reverse transcriptose inhibitors.' 4-Cyanopyrazoles show significant biological activity in inhibiting alcohol dehydrogenase? These compounds also produce skeletal muscle relaxation on administration to animals? Hasseneen and co-workers4 prepared these compounds by the reaction of nitrilimines with fumaronitrile. Junek and co-workers5 reported the synthesis of 4-cyanopyrazoles from cyanoacetaldehyde. Previous syntheses involve refluxing 3-dimethylamino-2benzoylpropenenitrile (2a) with phenylhydrazine or hydrazine in ethanol. However, the products were always a mixture of 4-cyanoand 5-aminopyrazole derivatives, which had to be separated by column chromatography> We now report a new chemoselective method to synthesize 4cyano or 5-aminopyrazoles. Reflux of 3-dimethylamino-2-benzoylpropenenitriles (1) and hydrazines (2) in ethanol in the presence of catalytic amount of hydrochloric acid furnished 4-cyanopyrazoles (3) as the sole products in 60-70% yield; 5-aminopyrazoles were not detected. The structure of 3 was established by analytical and spectral methods (Scheme I). The IR spectra show distinct usually


The feasibility of using microphones to measure intermodulation effects above a buried mine is under investigation at the U.S. Army RDECOM CERDEC Night Vision and Electronic Sensors Directorate. Acoustic mine detection techniques employ acoustic energy to excite soil and buried mines. The resultant linear and nonlinear response at the surface can then be measured using non‐contacting vibrometers. Carrier signal scattering by rough surfaces, however, can limit the measurement accuracy of these vibrometers and, subsequently, successful detection of the landmine. A microphone is proposed as an alternative non‐contact sensor specifically for nonlinear acoustic mine detection applications. In this scenario, distinct frequency content facilitates separation of the intermodulation effects at the surface from the acoustic excitation. Experimental results employing intermodulation effects for acoustic mine detection have been reported in the literature [Donskoy et al., J. Acoust. Soc. Am. 111, 2705–2714 (2002)]. Preliminary experimental results demonstrate the ability of microphones to sense pressure radiated from soil in the presence of realistic ground velocities. The applicability of these measurements to practical mine detection systems will also be addressed.


There are many methods to estimate geotechnical parameters through field tests like SPT and CPT, but these require soil disturbance. Recently, geophysical prospecting is performed using methods to estimate Vs, Vp, and resistivity, but the use of geophysical prospecting to estimate geotechnical parameters is limited due to a lack of correlations between non-destructive properties and geotechnical parameters. In this study, triaxial compression tests were performed to estimate geotechnical parameters for sand. Piezoelectric element and probe set up a top and bottom cap, respectively and measured elastic wave and resistivity during consolidation step. As a result, void ratio which was calculated from elastic wave are very similar with volume based void ratio. It means that non-destructive properties from geophysical exploration can be applied to estimate the geotechnical parameters.


The effect of different concentrations of mannitol,paclobutrazol and agar on Dracocephalum moldavica L.in vitro plantlet preservation were studied.The results showed that the survival rate of the plantlets growing in the condition of 1/4MS medium was lower than that in the condition of MS and 1/2MS medium at earlier stage,however its survival time had extended for more than 4 months.The growth of vitro plantlet was significantly inhibited by using mannitol,however its survival time had also extended for more than 4 months.The growth of vitro plantlet was significantly promoted by paclobutrazol,the survival rate of vitro plantlet was 50% in the condition of 2.0 mg/L which could extend for 4-9 months.MS medium added with agar 8.5-10.5 g/L was the best condition for the growth of Dracocephalum moldavica L.in vitro plantlet,which couod be saved for 12 months with a high survival rate of 85%-60%,and the plantlets grew well with no difference compared with the control groups.


The Koraga are a tribal community found mainly in the Dakshina Kannada, Udupi, Uttara Kannada, Shimoga and Kodagu districts of Karnataka and the Kasaragod district of Kerala, South India. These Areas in Karnataka are altogether often referred to as Tulu Nadu. Material culture which is in practice among the Koragas and other tribe has been supporting them to lead self-sufficient life without any menace. However, as a result of industrialization, urbanization, market economy, governmental policies and rehabilitation etc. their material culture is fading. At this backdrop, the present paper analyzes the material culture of the Koraga tribe and also suggests the conservation of material culture.


Microblogging services have been significantly increased nowadays and enabled people to share conveniently their sentiments (opinions) with regard to matters of concerns. Such sentiments have shown an impact on many fields such as economics and politics. Different sentiment analysis approaches have been proposed in the literature to predict automatically sentiments shared in micro-blogs (e.g., tweets). A class of such approaches predicts opinion towards specific target (entity); this class is referred to as target-dependent sentiment classification. Another class, called open domain targeted sentiment classification, extracts targets from the micro-blog and predicts sentiment towards them. In this research work, we propose a new semi-supervised learning technique for developing open domain targeted sentiment classification by using fewer amounts of labelled data. To the best of our knowledge, our model represents the first semi-supervised technique that is proposed for open domain targeted sentiment classification. Additionally, we propose a new supervised learning model for improving accuracy of open domain targeted sentiment classification. Moreover, we show for the first time that SVM HMM is able to improve accuracy of open domain targeted sentiment classification. Experimental results show that our proposed technique outperforms other prominent techniques available in the literature.


Social infrastructure projects (SIP), as the name implies, is defined as those buildings, structures and facilities specifically constructed to serve the community at large. The most apparent form of the social infrastructure projects are hospitals, schools and community facilities. Consequently, the nature of the infrastructure attracts less attention. In a sense, social infrastructure projects are one of the main criteria to enhance the economic productivity. This paper aims to contribute to this overlooked but important research line. There are two objectives of this paper. Semantically, this paper comprehensively reviews the social infrastructure literature from various aspects and applications. Then, it reviews nine journal papers and one conference paper in terms of ontology, epistemology and methodology. The preliminary finding reveals that ontological subjectivism, epistemological interpretivism, and qualitative analysis have dominated the social infrastructure domain. Last sections of this paper discuss the limitations and future research directions. The outcome can be used to improve general understanding of the social infrastructure projects.


In this work, samples of 15 mol% Sr-doped Al2O3 were synthesized by Pechini's method and calcined at 900°C. DRX analysis showed that only corundum phase is present, and no shift on the main peaks was observed, suggesting that the additive is preferentially located on the surface of nanoparticles as a surface excess. SrO show high basic character and is applied as heterogeneous catalyst in transesterification of soybean oil to produce biodiesel. Since SrO is difficult to obtain through Pechinis method, due to high stability of SrCO3, the use of Al2O3 as a catalyst support produced via polymeric precursor was studied, and the reaction of transesterification was successfully made, because the crystallization of strontium carbonate on the corundum surface was avoided using the washing procedure. Also, the catalyst was characterized by DSC, isoelectric point and surface area.


The ultra-high molecular mass polyethylene (UHMMPE) as an artificial joint acetabular material was filled with nano-powder of Al2O3 of various mass fractions. The effect of Al2O3 mass fraction on the hardness, wetting property and tribological properties of the Al2O3-UHMMPE composites under dry friction sliding against both stainless steel and Ti-6Al-4V alloy was investigated. The morphologies of the worn surfaces of composites were observed with optical microscope. The results show that, wetting property and wear resistance of the composites are improved by filling Al2O3, while the friction coefficient is decreased largely under dry friction as compared with that of the unfilled UHMMPE. This is attributed to the reinforcing function of the nano-powder of Al2O3 in the composites. The wear of UHMMPE is dominated by plowing, plastic deformation and fatigue wear; while the Al2O3-UHMMPE composites are characterized by the mild fatigue wear.


The present invention provides a memory device and a method of make same. The memory device comprises a substrate of semiconductor material of a first conductivity type, first and second spaced-apart regions in the substrate of a second conductivity type, with a channel region in the substrate therebetween, a conductive floating gate over and insulated from the substrate, wherein the floating gate is disposed at least partially over the first region and a first portion of the channel region, a conductive second gate laterally adjacent to and insulated from the floating gate, wherein the second gate is disposed at least partially over and insulated from a second portion of the channel region, and a stressor region of embedded silicon carbide formed in the substrate underneath the second gate.


This research project proposes a plan for the redevelopment of the Monastery in Cumberland, Rhode Island. The study will detail the history and cultural value of the site to the people of Cumberland, Rhode Island. The environmental setting will be defined and evaluated to determine environmental constraints to development through Geographic Information System (GIS) mapping and a site survey of existing conditions. The site will also be evaluated through the perspective of land use regulations, political issues, and trends in programs for the preservation/ protection of open space. A major consideration in the development of this plan was the Town of Cumberland's Comprehensive Plan, which was revised in 2003. Specific recommendations identified in the Comprehensive Plan under the Natural Resources Element, Public Services and Facilities Element, Cuhural resources Element, and Open Space/ Recreation Element have also been identified for further analysis in this study. The work of the Cumberland Land Trust, the Rhode Island State Planning ProgramGreenways Council, and other Federal, State, and Local Programs will be explored to provide open space linkages to the study area. A concept for the redevelopment of the study area into a 'Community Resource Complex' will be presented. The plan includes: the relocation of the historic Town Hall facility; the creation of a preschool educational facility; the creation of a Town-wide information center; enhanced and expanded passive and active recreation areas; open space acquisitions and linkages; a maintenance and stewardship plan for both public and privately-owned open space; and the overall goal of creating a 'sense ofpJace' for Cumberland's residents.


BMJ Learning offers online learning resources to train and test your skills in a variety of clinical and non-clinical topics. We aim to publish new modules every month, and this month we have "Deep vein thrombosis."

A general practitioner with a list …


Abstract Species delimitation in foliose macrolichens has long been dominated by chemotaxonomy, resulting in many examples of seemingly morphologically identical species that differ only in the secondary metabolites they produce. This study examines two such species that are widespread in southeastern North America: Parmotrema madagascariaceum (Hue) Hale and Parmotrema xanthinum (Müll. Arg.) Hale. Drawing on data from biogeography, chemistry, morphology, and molecular phylogenetic analyses of nuclear ribosomal internal transcribed spacer sequence data, the two species are treated as conspecific. A taxonomic treatment is presented along with a discussion of previous studies that have examined the delimitation of species that differ only in the presence or absence of compounds that are accessories in addition to a primary set of substances present in both species.


The strain of Thiobacillus ferrooxidan was isolated from the Sorange coal mine water in ferrous sulphate medium. The effects of inorganic nitrogen (NH 4 +, NO 3 -) and phosphate on the biological oxidation of copper sulphide ore were examined. It is observed that the iron was solubilized first from FeS 2 or Fe 1 - x S to as Fe + + and then oxidized to Fe + + + . The dissolution of iron Fe + + was a chemical reaction whereas the conversion of Fe + + to Fe + + + was bacteria mediated. The addition and increase in the concentration of phosphate delayed and reduced the conversion of Fe + + to Fe + + + . Ammonium was found to be the preferred source of nitrogen for the isolated bacterium. The nitrogen as NH 4 + increased the Fe + + oxidation whereas NO 3 - had negative effect. The solubilization of copper was directly related to the Fe + + iron oxidation. Maximum dissolved copper concentration were observed in 6mM ammonium supplemented medium and minimum in 6mM nitrate.


BACKGROUND AND AIMS
This study was done to detect the prevalence, risk factors for vaginal candidiasis in Chennai and to evaluate different methods for speciation of Candida isolates from vaginal candidiasis patients. This study was also aimed at detecting resistance patterns of Candida spp to common antifungals and at detecting mutant FUR1 genes in 5-Flucytosine (5 FC) resistant isolates.

MATERIAL AND METHODS
Two hundred clinically suspected vaginal candidiasis patients were screened for candidiasis and isolated Candida were speciated by standard morphological and biochemical tests (sugar fermentation and assimilation) and by using CHROM agar-Candida medium. Antifungal susceptibility was performed by disk diffusion method (CLSI M44-A) using fluconazole, itraconazole and 5FC disks. Five FC resistant isolates were subjected to PCR for detection of mutant FUR1 genes.

RESULTS
A total of 72 (36%) Candida spp. were obtained. Vaginal candidiasis was more prevalent in 31-40 years age group and among those with poor genital hygiene and who wore tight fitting synthetic/nylon underclothes . C.albicans (35), C.tropicalis (8), C.glabrata (21), C.krusei (4) were identified by both carbohydrate assimilation test and by using CHROM agar-Candida medium. C.kefyr (2) and C.parapsilosis (2) could not be identified using CHROM agar-Candida. Resistance to fluconazole, itraconazole and 5-flucytosine was seen in 19.44%, 23.61% and 41.66% of the isolates respectively. Mutant FUR1 gene was detected in all the Candida spp that were resistant to 5FC.

CONCLUSION
C.albicans was the commonest species which caused vaginal candidiasis in Chennai. Though CHROM agar-candida medium is a useful differential isolation medium capable of early presumptive identification of Candida species, it could not identify C.kefyr and C.parapsilosis. Azole resistance was low in C. albicans but it was high in non-albicans Candida spp. Prevalence of primary resistance to 5-flucytosine was high in the strains studied and in all of them, it was mediated by mutant FUR1 gene.


An expression for maximum accelerated particle energy E max due to the first-order shock-Fermi process is generalized to relativistic flows. Given the Bohm diffusion approximation and a mean ISM magnetic field of 3 µG, then E max ≈ 8 × 10 15 β 0 Z(m ⊙ /n 0) 1/3 eV for an uncollimated explosion expanding into a uniform medium with density n 0. The initial flow speed of the explosion is β 0 c, and the total ejecta energy, in Solar rest-mass energy units, is m ⊙. Second-order stochastic processes in relativistic flows can accelerate cosmic rays to ultra-high energies. Sources of mildly relativistic or relativistic flows with adequate power, namely fireball transients and gamma-ray bursts, are proposed as the sources of cosmic rays near and above the knee of the cosmic-ray spectrum.


An optimal capacity, when the binding use constraint is ecological damage, and monetization of recreational benefits, under alternative means of rationing that capacity, were conceptually and empirically developed. The model was developed by first estimating the demand to float Westwater Canyon, derived from a modified travel cost model. Recreational benefits of $6,500 under a hypothetical capacity of 50 trips, when pricing was used to allocate the permits, and a range of benefits from as low as $880 to an expected value of $3,690, if a lottery system is used, were estimated using this model. The monetization of the efficiency losses associated with more equitable allocation systems allows managers to be more objective in making the equity-efficiency trade-offs involved in picking a recreation use allocation system.


The coastal zone in Ukraine is likely to undergo the most profound change in the near future. Already more than 65 percent of the Ukrainian Black Sea region population lives within 30 km of the coast. Consequently, unless territory planning and careful environmental management are instituted, sharp conflicts over coastal space and resource are likely, and the degradation of natural resources will stop future social-economic development. In order to maintain and restore coastal ecosystem it was implemented law about formation of the national ecological network of Ukraine. Later were developed General Scheme for Planning of the Territory of Ukraine and regional level planning scheme but there is no especial document regulating the use of land in the coastal zone. The study of geographical conditions, economic activity, and population resettlement shows separation within the regions of several echelons of economic development in relation to the coastline. Such separation may be based on differences in intensity and types of economic use within the territory and the water area, as well as the population density on the land. These features include the following economic stripes: seaside-facade, middle, peripheral – on land, and coastal, territorial waters, exclusive economic zone – in the direction of the sea. At the same time, each economic stripe has a complex internal structure. There are several basic principles of functional zoning of the territory highlighted in the article can help to rational plan the seaside regions.


In this paper we present the reduced rank ensemble Kalman filter (the RREnKF) algorithm and its
application. Kalman filter is an estimation method of the state of stochastic dynamic system. The ensemble Kalman filter (EnKF) is modification of Kalman filter algorithm to estimate the non linear stochastic dynamic system. The Square root EnKF is an algorithm to keep the numeric stability, but need more computational time. Here we analyze
the reduced rank EnKF (RR-EnKF) as an alternative to reduced the computational time, and keep the accuracy estimation. We applied the RR-EnKF algorithm in some cases.


Abstract INTRODUCTION THE absence of chalazae in early oviducal eggs has often been observed. Hansen (1933) found that the chalazae became visible at about the time the inner thin white was formed, that is. while the egg was in the uterus. He believed that the chalazae were formed from the viscous, thick white by a rotation of the egg contents while the viscous white is fixed at the two poles. He attributed these movements to a flow of salt solution into the egg which also took part in the formation of the inner thin white. Richardson (1935), on the other hand, held the view that the chalazae were secreted by a specific part of the oviduct. He described mucous cells in a portion of the oviduct located between the funnel (the latter being approximately 3.5 cm. long) and the cephalic end of the magnum (albumen secreting region). These cells make up . . .


Transfemoral approach is considered the preferred route to perform transcatheter aortic valve implantation (TAVI) by most operators due to the low invasiveness and good outcome, as compared to non‐transfemoral approach. However, transfemoral access is not always feasible particularly in patients with small and calcific vessels. Recently, catheter‐based lithoplasty has emerged as a new technique based on the use of circumferential pulse pressure waves to disrupt calcific plaques. This technology may help to expand eligibility for transfemoral TAVI to patients with calcific ileo‐femoral vessels and at high risk for non‐transfemoral approach. We present the case of an 87‐year‐old woman with poor vascular access who successfully underwent transfemoral TAVI following lithoplasty of iliac artery.


Objective To understand the epidemic situation of influenza among children in Nanning,provide scientific evidence for the prevention and treatment of children influenza.Methods Surveillance files,virus isolation and identification results of children influenza-like illness(ILI) cases in Nanning during 2008-2010 were analyzed.Results Totally 407 773 cases were monitored during 3 years,in which cases with influenza like illness(ILI) accounted for 36.58%.Collected 1 861 samples,from which 140 strains of influenza virus were isolated(7.52%).Among the virus isolated,16 strains were type A(H1N1),19 strains were new type A(H1N1),57 strains were type A(H3N2),30 strains were type B(Victoria),18 strains were type B(Yamagata).Conclusion From 2008 to 2010,the predominant strain of Nanning children's flu epidemic was type A(H3N2).The influenza monitoring should be further strengthened,and the emergence of influenza virus variants and its epidemic trend should be attentioned.


Abstract—Lysophosphatidylcholine (lysoPC), which is generated in oxidized LDL (Ox-LDL) and abundantly exists in atherosclerotic arterial walls, has been shown to alter various endothelial functions and induces several endothelial genes expressed in atherosclerotic arterial walls. Nuclear factor-kappa B (NF-κB), a pleiotropic transcription factor, plays an important role in regulation of expression of various genes implicated in atherosclerosis. We have previously reported that lysoPC transferred from Ox-LDL to endothelial surface membrane activates endothelial protein kinase C (PKC), leading to modulated endothelial functions. This study was aimed at determining whether lysoPC could modulate activity of transcription factors in cultured human umbilical vein endothelial cells (HUVECs) by using electrophoretic mobility shift assay. LysoPC was found to increase DNA-binding activity of NF-κB in HUVECs within 15 minutes, which peaked at 1 to 2 hours and subsequently declined to the baseline level at 6 hours. L...


Risk assessments are typically based on retrospective reports of factors known to be correlated with violence recidivism in simple linear models. Generally, these linear models use only the perpetrators' reports. Using a community sample of couples recruited for recent male-to-female intimate partner violence (IPV; N = 97 couples), the current study compared non-linear neural network models to traditional linear models in predicting a history of arrest in men who perpetrate IPV. The neural network models were found to be superior to the linear models in their predictive power. Models were slightly improved by adding victims' report. These findings suggest that the prediction of violence arrest be enhanced through the use of neural network models and by including collateral reports.


Coal mining area of a power supply control system design,and power load control system leakage protection analysis.Thereby increasing the device power control system status assessment of accuracy,improve equipment maintenance work of rationality,efficiency and economy,improve the condition-based maintenance management of the intelligence level.


Abstract A new procedure based on closed vessel Microwave-Induced Combustion (MIC) technique is proposed for the decomposition of petroleum coke and further determination of sulfur by Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES). The procedure is based on sample ignition by microwave radiation using closed quartz vessels pressurized with oxygen and use of NH4NO3 as an ignition aid. The nature and concentration of absorbing/refluxing solution were studied, as well as the operational parameters related to MIC technique. Results were compared with those obtained by conventional wet digestion in closed vessels, certified reference materials (agreement was better than 98%), and also using ion chromatography for S determination.


Black crusts on stone surfaces, mainly composed of gypsum crystals, not only aesthetically affect the stonework but also cause further decay. Appropriate conservation methods should nondestructively detect the pollutant type and extent. In this paper, we propose a computer aided diagnostic method for automatically detecting deterioration patterns on black crusts. The proposed non-destructive method can be applied in situ. The applied detection process quantifies the alteration due to weathering and assesses the efficiency of several chemical cleaning methods. The detection process is based on a combination of Gaussian and morphological filtering. The results of both methods are fused via a Conditional Thickening operation in order to obtain reliable results concerning the spatial density, topology and extent of the deterioration patterns, while preserving their extent and shape characteristics. The algorithm is tested with a series of images depicting the corrosion state on marble surfaces. Decay patterns, classified by their chemical composition as black and white particles, are significantly decreased after the chemical cleaning, as indicated by the applied algorithmic approach. The corrosion alteration after cleaning is quantified in terms of robust statistical metrics expressing the extent, spatial density and thickness of the crusts.