As increasing elderly population and economics, design standards and detailed guidances are not enough because just facility standards are expressed in act for elderly welfare. Espcially, developing facility model, which is possible to reflect various claims from elders, is insufficient because elderly residential welfare facilities and elderly medical facilities are divided from elders' health conditions. The serious case the elderly people at April 2007. But, for reducing the estimate, We must reserve a health change for worse prevention program facilities for healthy old man. Therefore, this study is proposing to develop design standards and ruling and revise related regulations to keep elders' wealthy life in the aging society improving through analyzing twenty-one elderly welfare facilities in Seuol, ChungCheungBuk-Do, Jeollanam-Do, Gyeongsangbuk-Do.


DURING recent years the work of Son ne (1915), Aoki (1921,1923), Clayton and Warren (1929), Sartorius and Reploh (1932), and especially Boyd (1931, 1932, 1936, 1938) has greatly clarified the retiological position ofthe mannitefermenting organisms isolated from dysentery cases. The now recognized types, identified by serological methods, account for over 98 per cent of all the Flexner-like bacilli cultivated from the stools of patients in India suffering from dysentery. And there is little doubt that these classified bacteria are true retiological agents in the causation of the disease. The position of one of the types described by Boyd-DI9-still remains, however, in doubt. The reported isolations of this organism have been very infrequent and no fresh strain has been recovered in India during the last four years. When the original culture was re-examined in 1936 it was found to be irreversibly rough and to be serologically identical with the rough phase of Bact. dysenterim Sonne. It is felt that its occurrence, therefore, may be even rarer than the reports would indicate. In addition to the recognized types a small group of serologically unrelated Flexner-like organisms is met very occasionally in the stools of dysentery cases in India, whose significance remains in doubt. Nearly 2,000 strains of Flexner-like organisms undergo serological investigation every year, and during the last three years only nine of these rare types have been encountered (type 83 once, type 1063 three times, type 197 twice, type 953 three times). And during this period no other new types have been found where the evidence was sufficient~ to pronounce them as causative organisms of dysentery. On the other hand, considerable numbers of cultures of Flexner-like bacilli, cultivated from the stools of dysentery patients, have been received for detailed investigation on the grounds that they failed to react with any of the group or type sera prepared and issued by the present writer. It is this group, representing about 1 per cent of the mannite-fermenting . bacilli isolated during the routine examination of dysentery stools, that forms the subject of this communication.


Business and Economic Research (BER) would like to thank the following reviewers for reviewing manuscripts from March 1, 2021, to June 1, 2021. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Many authors, regardless of whether BER publishes their work, appreciate the helpful feedback provided by the reviewers. Macrothink Publishing appreciates the following reviewers' rigorous and conscientious efforts for this journal. Each of the reviewers listed below returned at least one review during this period. Abeer M. Ali Abd ElkhalekAhmed ZouhairAlina IaniogloAlmir A. AlihodžićBilal Khalaf SakarnehBratu (Simionescu) MihaelaCosimo MagazzinoCristina Alina NaftanailaElena GurguGerasimos T. SoldatosMamta SinghNana Osei-BonsuNuno DominguesOleksandr Volidimirovich DluhopolskyiRomeo Victor IonescuSantosh B. ManjegowdaYu HsingZi-Yi Guo


Introduction. 1: Thermoelastic Materials with Voids. 1.1. Preliminaries. The Laws of Thermodynamics. 1.2. Constitutive Equations. Thermodynamic Restrictions. 1.3. Boundary-Initial-Value Problems. 1.4. Continuous Data Dependence and Uniqueness Results. 1.5. The Linear Theory. 2: Dynamic Theory. 2.1. Uniqueness Results. 2.2. Reciprocal Theorem. Applications. 2.3. Homogeneous and Isotropic Bodies. 2.4. Acceleration Waves. 2.5. Harmonic Waves. 2.6. Concentrated Loads. 2.7. Radiation Conditions. 2.8. Potentials. 3: Equilibrium Theory. 3.1. Thermoelastic States. 3.2. The Thermoelastic Plane Strain. 3.3. Exercises. 4: Prestressed Thermoelastic Bodies. 4.1. Equations of Perturbed Motion. 4.2. An Existence Result. 5: Thermoelastic Cosserat Continua. 5.1. The Linear Theory of Micropolar Thermoelasticity. 5.2. Thermoelastic Processes. Boundary-Initial-Value Problem. 5.3. Reciprocity. Existence and Uniqueness Results. 5.4. Variational Theorem. 5.5. Homogeneous and Isotropic Solids. Plane Waves. 5.6. A Representation of Galerkin Type. Fundamental Solutions. 5.7. Transient Waves. 5.8. Plane Strain Problem. 5.9. Bending of Micropolar Thermoelastic Plates. 5.10. A Generalized Theory of Micropolar Thermoelasticity. 6: Thermoelastostatics of Micropolar Bodies. 6.1. Boundary Value Problems. Basic Theorems. 6.2. Special Results for Homogeneous and Isotropic Bodies. 6.3. The Equilibrium Plane Problems. 6.4. Exercises. 6.5. Thermal Stresses in Beams. 6.6. Cylinders Composed of Different Materials. 7: Nonsimple Materials. 7.1. The Nonlinear Thermoelasticity. 7.2. Uniqueness and Continuous Dependence results. 7.3. Linear Theories. 7.4. Isotropic Bodies. 7.5. A Grade Consistent Theory of Micropolar Thermoelasticity. References. Index.


Considered one of the wonders of world by medieval geographers, the Umayyad mosque at Damascus, with its shimmering gilded glass mosaics, had a tremendous impact on medieval Islamic architectural decoration. The mosque was, and continues to be, one of the most celebrated and frequently visited holy places in the Islamic world. One of the largest congregational mosques of its day, it served as a gathering place for the citizens of Damascus. No wonder the fledgling Mamluk state chose to patronize it, in the process situating themselves in a long line of legitimate Muslim leaders. Its splendor, expansiveness and expensive contruction represented the prosperity and grandeur of the fourteenth century.


Apparatus for encapsulating parts of elements into a plastic material to manufacture electronic components. The mould has one or more parallel rows of mould cavities, into which a plastic material is injected through one or more sprues. The elements are part of a strip of which the length is a multiplicity of the length of a row of cavities, which strip is step by step treated in said mould such that an uninterrupted strip of components is obtained.


This article introduces a 32-kHz crystal oscillator (XO) with high energy-to-noise-ratio pulse injection at subharmonic frequency. A T/4-delay clock slicer is proposed to convert the sinusoidal crystal waveform into an output clock of 32 kHz and to introduce a delay of T/4, providing proper timing for energy injections. The output clock feeds frequency dividers and generates pulses to activate the proposed all-NMOS differential driver at 4 kHz. It enables two injections in eight periods at the peak and valley of the crystal oscillation, with the crystal running freely between injections. This configuration achieves a 2-ppb Allan deviation floor. The less frequent injections reduce the injection overhead, enabling the lowest reported power consumption of published nW XOs (0.51 nW). At 0.45 V, the proposed XO operates across a temperature range of $- 25\,\,^{\circ }\text{C}$ to 125 °C, the widest reported range for nW XOs. This design is fabricated in the 40-nm CMOS and occupies 0.02 mm2.


This paper summarizes multiple perspectives of the common operational picture (COP) in military and civilian crisis management domains viewed from three vantage points: historical, conceptual, and practical. The term COP extends prior research on large group displays to describe a visual representation of tactical, operational, and strategic information intended to generate situation awareness. We present four strata of interest to formulate an innovative conceptual framework of the COP based on user-team needs: structure, representation, processes, and management. This conceptual framework is applied as part of a review of recent and ongoing projects that examines current research gaps in the application of geographic information systems (GIS) to international humanitarian response.


To reduce the possibility of misjudgement of the static damage identification results of bridge strucure identified by the defelction method,a damage identification model for the strucure is established according to the displacement continuity conditions.By approaching the calculated deflection value to the measured one and making the relative rotation angle of the node the least,the static damage identification method based on the displacement continuity is proposed and the multi-objective optimization method is used to provide the solution.The correctness of the method is verified by way of example of a simply-supported girder and the results show that the method comprehensively takes into account of the two displacement continuity conditons of the deflection and relative rotation angle,is more close to the practical situations and can reduce to a certian extent the misjudgement of the damage.


The degradation of natural resources in arid and semi-arid areas was highlighted dramatically during this century due to population growth and transformation of land use systems. The Algerian steppe has undergone a regression over the past decade due to drought cycle, the extension of areas cultivated in marginal lands, population growth and overgrazing. These phenomena have led to different degradation processes, such as the destruction of vegetation, soil erosion, and deterioration of the physical environment. In this study, the work is mainly based on the criteria for classification and identification of physical parameters for spatial analysis, and multi-sources factors to determine the vulnerability of steppe formations and their impact on desertification. To do this, we used satellite data Alsat-1 (2009) IRS (2009) and LANDSAT TM (2001). These cross-sectional data with exogenous information could monitor the impact of the semi arid ecological diversity of steppe formations. A hierarchical process including the supervised image classification was used to characterize the main steppe formations. An analysis of the vulnerability of plant was conducted to assign weights and identify areas most susceptible to desertification. Vegetation indices combined with classification are used to characterize the forest and steppe formations to determine changes in land use. The results of this present study provide maps of different components of the steppe, formation that could assist in highlighting the magnitude of the degradation pathways, which affects the steppe environment, allowing an analysis of the process of desertification in the region 1. Presentation of the region The Djelfa region belonging to the semi-arid bioclimatic, has a fairly large area of land described the phenomenon of desertification. Having a texture usually dominant sandy soils used for agricultural development (as in the great plain of Djelfa syncline), which once denied the permanent cover, will be subject to severe wind erosion. Overgrazing is a second cause of degradation and loss of land. The forested areas like the case of Djebel Sahari Senalba and consisting primarily of older forests of Aleppo pine are in a state of degradation.


The authors update the current status for the measurement of the direct-CP violation parameters {epsilon}{prime}/{epsilon} in the KTeV experiment at Fermilab. Substantial statistics have been accumulated during the 1996-7 run and 1999 run for both {epsilon}{prime}/{epsilon} and rare K{sub L} decay searches. The first KTeV result on {epsilon}{prime}/{epsilon} published last year was Re({epsilon}{prime}/{epsilon}) = (28.0 {+-} 4.1) x 10{sup {minus}4} based on the 23% data from 1996-7 run. Combining with the previous E731, NA31 and the recent preliminary NA48 results, the grand average is Re({epsilon}{prime}/{epsilon}) = (19.3 {+-} 3.6) x 10{sup {minus}4} (with S = 1:49), more than 5{sigma} above zero. More data from both KTeV and NA48 after completing the analysis will further improve the precision of this measurement in the near future and hopefully further improve the agreement. New results on the branching ratio and form factor measurements of K{sub L} {r_arrow} {mu}{sup +} {mu}{sup {minus}} {gamma} using 1997 data are also presented. We find that BR(K{sub L} {r_arrow} {mu}{sup +} {mu}{sup {minus}} {gamma}) = (3.66 {+-} 0.04{sub stat} {+-} 0.07{sub syst}) x 10{sup {minus}7}. The form factor parameter {alpha}{sub K}* is measured to be {alpha}{sub K}* = {minus}0.157{sub {minus}0.027}{sup +0.025}. We make the first measurement of the parameter {alpha} from the D'Ambrosio, Isidori, and Portoles form factor, finding {alpha} = {minus}1.53 {+-} 0.09. This measurement of {alpha} limits the CKM parameter {rho} > {minus}0.2.


Automation of Land Records is one of the most important initiatives undertaken by the revenue department to facilitate the landowners of the state of Punjab. A number of such initiatives have been taken in different States of the country. Recently, there has been a growing tendency to adopt UML (Unified Modeling Language) for different modeling needs and domains, and is widely used for designing and modelling Information systems. UML diagramming practices have been applied for designing and modeling the land record information system so as to improve technical accuracy and understanding in requirements related with this information system. We have applied a subset of UML diagrams for modeling the land record information system. The case study of Punjab state has been taken up for modelling the current scenario of land record information system in the state. Unified Modeling Language (UML) has been used as the specification technique. This paper proposes a refined software development process combined with modeled process of UML and presents the comparison study of the various tools used with UML.


In today's society there is an increasing need for energy, an increase which for the most part is supplied by the use of fossil fuels. Fossil fuel resources are limited and their use has harmful ef ...


There is growing interest in this country in developing training programmes suitable for overseas psychiatrists. The motive is partly one of self-interest. The implementation of current Government policy means that many departments will look to overseas visitors to fill their registrar positions in excess of their career registrar allocation. This paper is the result of my observations during three weeks in Zambia, three in Tanzania and II days in Ethiopia. It is therefore inevitably impressionistic. It would be invidious to single out particular departments in a paper such as this. Impressions from all three countries have therefore been combined except where specified in the text. In general there was sufficient similarity between them for this not to introduce too great a distortion.


In this paper we demonstrate how an estimated functional kernel-regression polynomial from a particular RF technology can be created by the mobiles being served by that technology. A 3rd order polynomial description of the regression can be used to predict future throughput by observing the "pilot" quality prior to handover. The UE may use it to predict the throughput it will get in the new technology 50 to 200 m-sec prior to handover. The prediction can inform the Transport Control Protocol (TCP) layer or the application layer of the upcoming handover and the throughput expected after handover so that the user application receives the best quality of service. This paper is an extended version of the paper presented at IEEE Sarnoff Symposium 2015 [1]. It extends the paper with expanded foundational knowledge and explanation of the results and their implications. In this paper we: • propose that there is a way to predict the unobservable quality metrics in the new cell prior to commencement of the handover. This is achieved by 1) a prediction mechanism and 2) a signaling mechanism. In this paper we focus on the prediction mechanism. • propose that the observable metric ("pilot" quality) is predicted with prediction error below 9% with prediction step sizes of 200 m-sec. Journal of Cyber Security, Vol. 4, 233–258. doi: 10.13052/jcsm2245-1439.441 c © 2016 River Publishers. All rights reserved. 234 R. Sayeed et al. • show that the throughput metric (we choose bits/physical-resourceblock = β) can be predicted with error below 8% with prediction horizon of 200 m-sec.


The COVID- 19 pandemic has changed the pattern of society's life whether in the economic, social, educational and healthy environment to a new normative situation. In terms of education, schools and educational institutions had to be closed as long as the MCO Movement Control Order was gazetted. Many students and teachers are unable to attend school normally due to restrictions on social interaction. As a result, parents have to take over the task of teaching and monitoring their children's online learning at home (PdPr) which requires them to master various subjects, provide internet access and ensure adequate teaching materials. This requires parents to play a very important role in preserving the continuity of student education during the COVID-19 pandemic so that students are not left behind in learning when educational institutions open later. Thus, this study was conducted to examine the pattern of education during the COVID-19 pandemic, identify the role of parents in student learning at home and analyze the readiness of students in facing teaching and learning at home (PdPr). The methodology of this study is qualitative using content analysis design through the method of data collection by a document analysis of books, journal articles, proceedings and akbar related to the title and analyzed descriptively to answer the objectives of the study. The majority of findings of the study show that the role of parents is directly involved in monitoring, providing ongoing encouragement and assisting in student learning activities at home through various applications or digital platforms such as Whatsapp, Google Classroom, Zoom, Webex and Youtube. Further research is proposed to be conducted quantitatively to analyze the level of readiness of students and parents towards digital application based education in new norm and identify the challenges faced by students, parents and educators.


The effect of the balance-of-system (BOS), i.e., the total system less the modules, on photo-voltaic energy system costs is discussed for multikilowatt, flat-plate systems. Present BOS costs are in the range of 10 to 16 dollars per peak watt (1978 dollars). BOS costs represent approximately 50% of total system cost. The possibility of future BOS cost reduction is examined. It is concluded that, given the nature of BOS costs and the lack of comprehensive national effort focussed on cost reduction, it is unlikely that BOS costs will decline greatly in the next several years. This prognosis is contrasted with the expectations of the Department of Energy National Photovoltaic Program goals and pending legislation in the Congress which require a BOS cost reduction of an order of magnitude or more by the mid-1980s.


When we integrate information sources that are managed locally, the integrated objects are often semistructured, since di erent sets of information sources participate in forming each of the objects. Such integration requires outer join and conversion operators: outer join operators prevent information loss that would be caused by inner joins, and conversion operators are used to mediate the inconsistency among information sources. These operators impose restrictions on the order of query processing. This paper presents an algorithm for creating a processing plan to integrate information sources without information loss, in the presence of conversion operators. As a framework of our discussion, we use the TSIMMIS mediation system developed at Stanford University. Given a view speci cation and a query, we create an initial expression graph whose nodes represent query processing units, including outer join and conversion operators. Then, we convert the initial expression graph into an executable expression tree.


The article covers promotion as one of the marketing-mix elements of territorial marketing. In article priority directions of promotion of territorial formations from positions of a principle of economic realization, a principle of mutual benefit and a principle of long-term relations are considered. Also valuable characteristics both the most territorial formation, and its consumers are defined. The approach to a problem of territorial marketing from psychographic positions is given.


The evolution of cooperative, pro-social behavior under circumstances in which individual interests are at odds with common interests-circumstances characterized as social dilemmas-remains a largely unsolved, multidisciplinary puzzle. Approaches to these types of problems have, for the most part, been applications of evolutionary game theory. While the study of networks, complex systems, and nonlinear dynamics has pervaded most scientific disciplines, the application of related tools to the study of social dilemmas represents a very new, but extremely promising means of shedding light on the quandary of cooperation. In this work, we situate agents engaging in social dilemma games on complex social networks, allowing us to more fully investigate the impact of average degree and degree variance, or heterogeneity of degree, on the evolution of pro-social behavior. Our results suggest that increasing homogeneity of degree produces network effects that make the emergence of pro-social behaviors more likely thereby increasing overall social welfare. As such, homogeneity of degree is properly thought of as a collective good. Introduction Cooperation has been vital to the evolution of all living things, including singlecelled organisms (Velicer, 2005, 2003; Velicer & Stredwick, 2002; Crespi, 2001; Velicer et al, 2000; Boorman & Levitt, 1980), fish (Brosnan et al, 2003; Dugatkin, 1991, 1992, 1997; Milinski, 1987), birds (Brown & Brown, 1996; Faaborg et al, 1995), canines (Creel & Creel, 2002; Courchamp & Macdonald, 2001; Fentress & Ryon, 1986), felines (Caro, 1994; Packer & Pusey, 1982), non-human primates (Brosnan & de Waal, 2003; de Waal, 1996, 1982; Harcourt & de Waal, 1992; Chapais, 1992), and humans (Ostrom et al, 1999; Fehr & Fischbacher, 2003; Johnson et al, 2003). Even so, the evolution of cooperative, pro-social behavior under circumstances in which individual interests are at odds with common interests, (circumstances characterized as social dilemmas (Gotts et al, 2003; Dawes & Messick, 2000)), remains a largely unsolved, multidisciplinary puzzle (Hammerstein, 2003). Approaches to these types of problems have, for the most part, been applications of evolutionary game theory (Gintis, 2000; Hofbauer & Sigmund, 1998; MaynardSmith, 1982; Maynard-Smith & Price, 1973; Trivers, 1971; Hamilton, 1967; von Neumann & Morgenstern, 1944) and due to their importance as generalized models of many important socio-economic situations (Tomassini, 2006), iconic games such as the Prisoner's Dilemma have been widely employed as metaphors (Doebeli & Hauert, 2005; Axelrod & Hamilton, 1981; Axelrod, 1984; Nowak & Sigmund, 1992, 2004; Nowak & May, 1992; Maynard-Smith, 1982;Sugden, 1986). At the same time, the study of networks, complex systems, and nonlinear dynamics has pervaded all of science (Strogatz, 2001)1. Indeed, E.O. Wilson, who once characterized the evolution of cooperation as one of the greatest challenges for modern biology (Wilson, 2000), more recently made a more emphatic appeal for research on complex systems. "The greatest challenge today, not just in cell biology and ecology, but in all of science, is the accurate and complete description of complex systems. Scientists have broken down many kinds of systems. They think they know most of the elements and forces. The next task is to reassemble them, at least in mathematical models that capture the key properties of the entire ensembles." (Wilson, 1998: 85). The application of complex systems tools and network analysis methodologies to the study of social dilemmas represents a very new, but extremely promising means of shedding light on the quandary of cooperation (Hanaki etat, 2007; Fu et al, 2007; Ohtsuki et al, 2006; Santos et al, 2006a, 2006b; Szabo & Fath, 2006; Tomassini et al, 2006; Santos & Pacheco, 2005; Santos et al, 2005; Lieberman et al, 2005; Abramson Sl Kuperman, 2001; Skyrms &Pemantle, 2000). …


The article deals with the psychological attitude and its infl uence on students' foreign language skills. It addresses the problem of language attitudes and the reasons for language mistakes made by students. The role of students' attitude is marked on the level of social activity.


This study aimed to get empirical evidence of differences in disclosure of corporate social responsibility in corporate banking in Indonesia. In this study used banking companies grouped into two publicly traded banking companies and the government-run banking company managed by national private. Data used is secondary data obtained through the Indonesian Capital Market of Direnctory and website www.idx.go.id. The data used from the year 2011 - 2014 ago. The variables used were six indicators disclosure of corporate social responsibility program that includes economic, energy, labor attention, human resources, social and product. The analytical method used is quantitative using different test non parametric ie Mean Whitney. The processing is done by using SPSS. Based on the results of tests that have been carried out it was found that there were no significant differences in corporate governance disclosure as measured from the economic, energy, labor attention, human resources, social and banking product companies go public either government-run or privately managed. Keywords: Economic, Energy, Labor Attention, Human Resources, Social and Product.


Program Description: In the setting of decreased reimbursements and increased insurance denials, wading through the world of current procedural terminology (CPT) coding for nasal surgery can be challenging. This interactive miniseminar will discuss appropriate coding for nasal surgeries, clarifying the differences between rhinoplasty, vestibular stenosis repair, septoplasty, and turbinate surgery, and discuss indications for precertification. Individual speakers, well versed in the world of nasal surgery, will share strategies in documentation, patient counseling, and navigating appeals. The main goal of the miniseminar is to provide an algorithm for proper and accurate coding and helpful strategies to support these coding choices. Educational Objectives: 1) Maximize coding for nasal surgeries involving functional rhinoplasty, septoplasty, and treatment of inferior turbinates. 2) Recognize clinical indications that impact coverage of rhinoplasty by insurance companies. 3) Improve efficiency when interacting with insurance companies in the management of rhinoplasty coding.


While we are observing some "green shoots," it is too soon to speak of a recovery. We can, however, identify some key forces that are likely to shape any future growth path.


A team of researchers at Baylor College of Medicine has developed a family-based association test that improves the detection in families of rare disease-causing variants of genes involved in complex conditions such as Alzheimer's. The method is called the rare-variant generalized disequilibrium test (RV-GDT), and it incorporates rare, as opposed to common, genetic variants into the analysis. In families in which several members are affected by a genetic condition, RV-GDT proved more powerful than other family-based methods in detecting rare genetic variants causing the condition. The results appear in the American Journal of Human Genetics .


Patients and methods: Forty two pregnant women with gestational age > 32 weeks with IDA resistant to oral iron therapy alone were randomly assigned to intravenously ISC plus rhEPO or ISC alone 72-96 hour a part. Target hemoglobin value was 11 g/dl. Primary outcome were hematological respond to treatment by increase in hematocrit and reticulocyte count while the secondary outcomes were other hematological parameters, serum ferritin, patient's symptoms.


Abstract : Determining the state of the ground is critical for Objective Force operations. Currently, no methods exist to remotely, and accurately, measure the near-surface soil properties (strength, density, compressibility, and texture) needed to define ground state. Analysis of low-velocity impact probe deceleration, obtained during penetration, is the most practical method to remotely determine ground state. Development of the physics describing the behavior of the impact requires in-depth knowledge of the physical properties of the relevant soil. This report provides an extensive suite of calibration and verification material properties for predicting the response of an ASTM C33 sand to low-velocity probe penetration. The experimental program determined the following physical properties for this sand: elastic behavior (shear and Young's moduli and Poisson's ratio), strength characteristics (friction angle, cohesion, compressibility, and triaxial strength), and construction parameters (maximum/minimum densities, optimum moisture content, and California bearing ratio).


As a part of the DFG collaborative research center 483 'High performance sliding and friction systems based on advanced ceramics' the high potential of engineering ceramics shall be demonstrated on four exemplary choosen systems. The results that are given in the present study were gained whithin the research projekt C2 which works on the modelling of the damage behaviour occurring in clutches. For the thorough scientific examination of the degradation processes of ceramic materials two methods are applied. Experiments under high frictional loadings that are applied by a dry friction testing system are combined with the mathematical analysis using the Finite-Element-Method (FEM). For a deeper understanding of the origin and development of the damages resulting from the friction experiments 4-point bending tests and microfractography were carried out. The present paper deals with the results of these fractographic examinations as well as the determination of residual strength which depends on the stress history of the ceramic material.


This is a straightforward teaching aid for understanding the causes, pathophysiological changes and clinical features seen in disease processes. The text is well written and complemented by simple, explanatory diagrams.


PROBLEM TO BE SOLVED: To provide a roll support shaft of simple constitution detachable to a conventional winder and a conventional unwinding device, and requiring no core. SOLUTION: The roll support shaft 1 is constituted of a shaft main body 5 provided with radial protrusions 4 in a cylindrical hollow core part 3, and blade parts 7 connected to the protrusions 4 by link members 6. The each protrusion 4 is a member for connecting the each blade 7 to the shaft main body 5. The each blade 7 is formed into a plate like shape having 3-5 mm thickness and is slightly longer than the shaft main body 5 in its longitudinal direction, and a cross-section of the blade orthogonal to the longitudinal direction is formed into an L shape. The shaft main body 5 and the each blade part 7 are connected by laying the each link member 6 comprising a set of two sheets between the protrusion 4 and the blade part 7, by clamping the protrusion 4 with a longitudinal-directional one-end of the link member 6, and by clamping the blade part 7 with the other end, so as to be tightened with a rivet 8. The blade part 7 is approached and separated to/from the shaft main body 5 by the link member 6 while the blade part 7 is kept in parallel to the shaft main body 5. COPYRIGHT: (C)2004,JPO


AbstractThe recent emphasis on materiality in religion has encouraged a good deal of attention to materiality in Buddhism, but that attention has fallen entirely on Buddhist traditions with conventional monastic orientations. Yet the major Japanese Buddhist school known as True Pure Land Buddhism (Jōdo Shinshū) has also historically possessed a highly important, if different, material dimension, for which one touchpoint has been its merchant members called Ōmi shōnin who flourished in later premodern Japanese history. After alluding to the difficulty of isolating the 'material' in any religious culture, the article sketches the transition in Christian materialities in Europe which marked a cognitive shift from medieval modes of thinking (exteriorized, animistic-monistic, oriented to relics and ancestor religion) towards modern modes (interiorized, oriented to abstraction and the psychological individual). Against that paradigm, almost all premodern Buddhist materialities, including those in Japan, can be seen as medieval in nature. However, Jōdo Shinshū was a departure employing an innovatively interiorized doctrine. From that perspective, both Europe and Japan were highly complex civilizations displaying a long-term medieval-to-modern shift, which impacted the material manifestations of religions by gradually replacing older economies of ritual exchange with more modern-looking economies of preaching, religious publication and commercial life. Western scholarship has resisted appreciating these issues in an Asian setting.


That cerebral angiomata may simulate migraine is well known but the frequency of such a mode of presentation is not clearly established (Mackenzie, 1954). In the last 10 years many patients with migraine have been investigated by carotid angiography in the Royal Infirmary, Manchester, but very few have been shown to harbour an angioma. This has led to the impression that the relationship between migraine and angioma has been overstated. The first part of this study concerns 70 patients with proven intracranial angiomata.


Objective: PKCβII is a potential target for therapeutic intervention against pandemic diabetic complications. Present study probes the molecular interactions of PKCβII with its clinically important ligands, viz. ruboxistaurin, enzastaurin and co-crystallized ligand, 2-methyl-1H-indol-3-yl-BIM-1. Research design and methods: The essentials of PKCβII–ligand interaction, crystal water-induced alterations in these interactions and key interacting flexible residues are analyzed. Computational methodologies, viz. molecular docking and molecular simulation coupled with molecular mechanics-Poisson–Boltzmann surface area and generalized born surface area (MM-PB[GB]SA) are employed. Results: The structural changes in the presence and absence of crystal water molecules in PKCβII ATP binding site residues, and its interaction with bound ligand, are identified. Difference in interaction of selective and nonselective ligand with ATP binding site residues of PKCβII is reported. Conclusions: The study showed that the nonbonding interactions contribute significantly in PKCβII–ligand binding and presence of crystal water molecules affects the interactions. The findings of present work may integrate the new aspects in the drug design process of PKCβII inhibitors.


In their recent editorial, Suetani and Parker wrote, 'to advance the art of psychiatry and achieve clinical excellence, we must embrace and learn from our failures as well as our success'. They began by highlighting two contemporary facts aboutmental illness: recovery rates are not improving and life expectancy is worsening. They reiterated the Productivity Commission conclusion that more psychiatrists were needed, but added that improved quality of psychiatric practice was also needed. The rest of the piece essentially argued that one crucial method of improving quality was acknowledging and learning from 'failures' (ill-defined). The piece was, in a technical sense, reasonable. However, the irony of the editorial was that it failed to acknowledge its own conceptual failure. It spoke of mental health problems as though they are individual technical problems requiring individual technical solutions. It promulgated the narrow biomedical conceptualisation of 'mental illness' as a predominant problem of brain structure and function rather than a predominant problem of social structure and community in vulnerable people. The authors opined that without scrutiny of practice, psychiatrists risked 'playing golf in the dark', 'hitting the balls' but not 'knowing where they are going' – the implication being: psychiatrists are on the right track but just need to tweak their performance, 'much like a golfer may improve by making small adjustments to his techniques', to achieve 'clinical excellence'. But this confidently assumes psychiatrists are actually 'hitting balls' in the first place – what if they are actually taking air swings? Many argue that it is precisely this – the biomedical 'psychiatrisation' of human suffering – that is material to psychiatry's 'failures'. Suetani and Parker's call for 'direct observation of performance' and 'immediacy of feedback' may hone individual technical skills but will do nothing to ameliorate the key structural catalysts of mental health problems: poverty, violence, substance use, crime, social inequality and social marginalisation. As Jureidini recently wrote, 'changes need to be made to the conditions of living, rather than to the brains, of people who suffer'. Though potentially clinically useful, the suggestion of conducting psychological 'pre-mortems' on challenging cases ignores the reasons why the case became a 'case' in the first place. Regarding outcomes, the authors' push for more 'local' measurements may be clinically relevant but it overlooks the core issue – unless the social and structural determinants of the problem are addressed, refined measurements, nomatter how local, will not improve population outcomes.


This study investigated the equivalent perception between a visual stimulus and its associated sound. Auditory‐visual stimulus presentation experiments were performed using an audio‐video clip of a man beating a drum on a road. The visual stimulus, with a perspective view of the road, imparted a depth sensation. Visual stimuli were projected onto a screen of 30.8 (W) (B 16.1 (H) deg. In all, 315 auditory‐visual stimuli were produced with combinations of distance between the visual target (the drum) and the observer from (B00 m, the time delay between auditory and visual stimuli from −8F to 8F (1 F=1/30 s), and the sound pressure level of the sound stimulus from (B12 dB. The stimuli were presented to six subjects. In each presentation pattern, the sound pressure level to provide a perceptual strength equivalent to that of the visual target was determined: the equivalent sound pressure level (ESPL). Results show that the ESPL increased as the time delay between the auditory and visual stimuli increased, i.e...


A mini-conference on Hamiltonian and Lagrangian methods in fluid and plasma physics was held on 14 November 2002, as part of the 44th meeting of the Division of Plasma Physics of the American Physical Society. This paper summarizes the material presented during the talks scheduled during the Mini-Conference, which was held to honor Allan Kaufman on the occasion of his 75th birthday.


FIELD: information technology. SUBSTANCE: in the method, data are received from a source of content, the content is converted to a type which is suitable for the destination digital rights management (DRM) device, a content licence is created, which enables use of the converted content using the obtained information, the converted content and the created licence are transmitted to the destination object, a termination list is created, which identifies the terminated device and checks termination to access the converted content based on the termination list. EFFECT: providing interaction of the digital rights management (DRM) service with respect to different types of content. 9 cl, 14 dwg


In this paper, we explore the need, possibilities and opportunities for linking formal and non-formal education in Uganda with a view to helping learners acquire, build and sustain productive skills they need for creating wealth and enjoying sustainable livelihoods. We start the paper with a clarification of the difference between formal and non-formal education and a description of the characteristic features of each and the context in which they are provided in Uganda. Locating the paper in the capability approach, we argue that linking formal and non-formal education has a huge potential for promoting practice-oriented learning and skills application which will in the long run help to address the loopholes in Uganda's education system which many have described as theoretical and incapable of meeting the needs of people. We briefly describe methods we used and proceed to note that practice-oriented education is likely to maximize participation levels of ordinary Ugandans in government's poverty reduction programmes and facilitate the process of wealth creation and the attainment of the goals of prosperity for all in the country. We explore some of the good practices in non-formal education in Uganda and assess opportunities and possibilities for linking formal with non-formal education as a strategy for diversifying and recognizing the various learning options available for promoting and accelerating socio-economic transformation among the people. We highlight some of the challenges which are likely to be faced in an attempt to bridge the gap between formal and non-formal education and suggest the way forward. In concluding the paper we note that the dream of eradicating rural poverty and attaining prosperity for all in Uganda will remain wishful thinking if no deliberate attempts are made to appreciate diversity in learning and integrate as well as recognize the various learning options in country.


Flood vulnerability indices for the Kelantan River sub-basins were developed from various floodrelated variables. The vulnerability indices of the Ke lantan River sub-basins involved flood depth-inundation area, soil erosion potential, and potential of soil for agricultural use, population vulnerability, road infrastructure vulnerability and market infrastructure vulnerability. These indices were developed from the use of Geographic Information System (GIS) technique. The result indicates that the flood vulnerability indices of sub-basins were mostly ranked high in the areas with high concentration of development activities and densely populated region with large infrastructure exis tence that are more flood-prone group than others especially in major metropolitan areas. In order to steer against probable damage caused by flood, it remains important to develop a t ool that is most beneficial for river basin managers and policy makers, so that they can conduct vulner ability assessment and flood risk in term of human lives losses and property damages during future ma ssive floods. The output of this study can guide decision makers to reduce flood risks Kelantan River basin in future.


Software metrics are developed and used by the many software organizations for the evaluation and confirmation of good software code, working and maintenance of the software product. Software metrics measure and identify various types of software complexities such as size metrics, control flow metrics and data flow metrics. Such observed and calculated software complexities should be continuously calculated, understood and controlled. One of the significant objective of software metrics is that it is applicable to both a process and product metrics. It is always a clear fact that the high degree of complexity in modules is bad in comparison to a low degree of complexity in modules. Metrics can be used in different phases of the software development lifecycle. This paper reviews the theory, called "software complexity metrics for evaluation of software projects", and analysis can be done based on various static and dynamic parameters. We will try to evaluate and analyze various aspects of software metrics in determining the quality and improvise the working of the software product development.


Destruction of the DIP-joint and of the growth plate of the distal phalanx after frostbite is shown in the case of a 13-year-old boy. Clinical symptoms, therapy, and result of treatment are presented and literature reviewed.


Compounds with the postperovskite (PPv)-type crystal structure were searched using a Kawai-type multi-anvil high-pressure apparatus. We succeeded in synthesizing PPv-type CaRuO3, CaRhO3, NaNiF3, NaCoF3, and NaZnF3 and found that perovskite (Pv)-type NaMnF3 decomposes into two phases above about 10 GPa instead of phase transition to a PPv phase. The PPv-type CaRuO3, CaRhO3 and NaNiF3 are quenchable without partial back-transformation to the Pv-type structure. The structure refinements of the synthesized compounds suggest that PPv-type NaNiF3 and NaZnF3 are preferable to the other PPv-type compounds as analogue materials of PPv-type MgSiO3 which is accepted as a major constituent mineral in the Earth's lowermost mantle. [postperovskite, oxide, fluoride, Kawai-type high-pressure apparatus, quench method, Rietveld analysis]


An important concern for empirical analysis of market responses to public releases of information is whether the voluntary nature of announcement and publication decisions imparts a selectivity bias and, if so, how this bias affects empirical results. Using a database of SEC filings of equity issues, all related Wall Street Journal published announcements are identified. The published announcements are used to classify proposed issues into subsamples with homogeneous information structures. Announcement and WSJ publication decisions are found to be non-random but, for industrial firms, not significantly related to firm size or exchange listing. Coefficients estimated without controlling for selectivity are found not to be significantly biased for either industrial or utility issues. However, for industrial issues, significance levels are considerably lower when selectivity bias is controlled. The hypothesis common to other studies of new issue announcement effects that observations from different information structures can be pooled, with coefficient estimates restricted to be equal across information structures, is rejected. The results have implications for the methods used to study cross-sectional market responses


Railway transit forms the backbone of sustainable transportation systems, which are necessary to limit the effects of global warming. In this paper, the authors seek to determine whether there is a statistically significant difference in energy consumption between distinct railway vehicle types. Firstly, the energy consumption measurement methods in the railway transportation sector are described and compared to each other in respect to precision and cost. Secondly, the use of energy consumption as a criterion in rolling stock tenders with the associated norm is analysed, particularly with regard to the life-cycle cost of railway vehicles. In the next part real life data on energy consumption of six distinct passenger electrical railway vehicle types is presented and analysed in order to compare the efficiency of different types of rolling stock. The differences in energy efficiency between rolling stock types may be used to improve the procurement process ensuring train operating companies obtain less energy-consuming vehicles.


In this paper we present new numerical algorithms based on a generalized nonlinear Galerkin method in order to solve coastal and oceanic circulation problems. The equations system is based on the primitive equations of the ocean under Boussinesq and hydrostatic approximations. These equations are transformed using, at the same time, the classical σ transformation and an original homogenization of the boundary conditions. We use a well adapted special basis to apply the usual Galerkin method and the nonlinear Galerkin method. This basis is built on a modelization of the energetic transfers through the different scales of flow. Two approaches are proposed to solve the continuity equation: the (nonlinear) Galerkin method and the method of the characteristics. We present the advantages and drawbacks of both methods.


Continuous-time Delta-Sigma (DS) modulators are good candidates for applications in wideband and high-frequency data communication systems because of their high power efficiency. 4G system is a combination of different standards with different specifications, which requires that ADCs in such a system be reconfigured to minimize the power consumption for different specification. This paper tries to analyze and compare the different modulator topologies based on power consideration. A power-estimation method for DS modulator is presented and based on this method the optimal topologies in terms of power are found for several wireless standards with different specifications and this forms a design strategy for reconfigurable Delta-Sigma ADCs.


Place to do practical work is in PT Jasa Marga (Persero) Tbk Jakarta branch-Cikampek and placed at the Human Resources. The implementation of practical work undertaken with the aim to nd out how the calculation of Income Tax Article 21 of the permanent sta at PT Jasa Marga (Persero) Tbk and to know the com- ponents of gross income and deduction from gross income component is entitled to Permanent Employee of PT Jasa Marga (Persero) Limited in respect Income tax payable by 21 after doing calculations, PPh 21 due by the Company of Rp.164.213 Calculation and Income Tax Calculation 21 payable according to Law No. 17 of 2000 amounting to Rp 159.742.00. dierence in results was due to dierences in additive components and reducing the gross income of the calculation according to the company with the calculation according to Law No. 17 of 2000 so that it can be con- cluded that the calculation of income tax at 21 PT Jasa Marga (Persero) is not in accordance with 21 Calculation of Income Tax according to Law No. 17 Year 2000.


Clear and mostly traditional in its approach to verse analysis, with a new look at the development of versification in Modern English, Natural Emphasis makes wide-ranging use of recent theoretical and linguistic studies to examine the chief contributions of poets from Chaucer to Dryden.


This paper presents results of a comparative study that investigated the effects of different types of keyboard backgrounds (themes) on actual and perceived text entry performance, in terms of speed and accuracy. Two color and two image backgrounds were compared with the default Google Android keyboard. Results revealed that keyboard background does not affect actual performance, however has a significant effect on perceived performance. Most participants felt that image backgrounds, regardless of whether they were pre or self-selected, affected their speed and accuracy. This suggests that it may be possible to enhance one's text entry experience simply by designing an effective keyboard theme. This paper concludes with reflections on how these findings could benefit text entry researchers and keyboard developers.


MSI (mass spectrometry imaging) serves as an efficient and reliable tool for imaging certain molecules on biological samples. But the comprehensive understanding of the information from MSI has not been fully studied. In this paper, it is studied by coarse-graining how molecules spatially vary in the sample. We find that the double-exponential of entropy shows the power-law behavior in coarse-graining. The spatial distribution of the exponent provides new information for MSI. Experiments were performed using kidneys of mice. Heat maps of the exponent showed high values in the renal pelvis area and low values in the medulla area. Spots within and around the veins and arteries were distinguished from those composed of kidney cells. The method reveals and visualizes changes in the diversity of full chemical information obtained by MSI.


Describes a system and method for transmitting and receiving captured by the imager focal plane array comprises a plurality of image data. An embodiment of the present invention comprises: a plurality of active focal plane of a camera module using the captured image data, where an image is formed on the focal plane of each lens by a separate active laminate; interleaved by a plurality of said movable by the focal plane of the captured image data to generate image data line; and transmitting line image data and the additional data.


To further improve the steady-state performance of the convex combination of adaptive filter for variable fractional tap-length least mean square(CFTLMS) algorithms,a convex combination of variable width(VW) and variable tap-length adaptive filtering algorithm is proposed based on the proof of the steady-state performance of CFTLMS algorithm,and the choice principles of parameters are given.Simulation results show the correctness of steady-state performance analysis and parameter selection principles of the VW-CFTLMS algorithm under lower SNR condition,and the steady-state performance of the algorithm is superior to that of the CFTLMS algorithm,of which the excess mean square error is lowered by about 1.8 dB.


Connectivism is a newly emerging e-learning theory internationally,considered to be a landmark theory for the digital age.Based on neuroscience,this theory describes study as a process,in which a large number of nodes interconnects with each other to constitute a network.Compared with the former theories,connectivism is more flexible,and closer to the human brain.Although some people still questioned connectivism's status to lead learning theory's new development,this theory's new ideas and its unique perspective will undoubtedly promote the new development of learning theory research.


Research and experimentation on live hyperscale clouds is limited by their scale, complexity, value and and issues of commercial sensitivity. As a result, there has been an increase in the development, adaptation and extension of cloud simulation platforms for cloud computing to enable enterprises, application developers and researchers to undertake both testing and experimentation. While there have been numerous surveys of cloud simulation platforms and their features, few surveys examine how these cloud simulation platforms are being used for research purposes. This paper provides a preliminary systematic review of literature on this topic covering 256 papers from 2009 to 2016. The paper aims to provide insights into the current status of cloud computing research using open source cloud simulation platforms. Our two-level analysis scheme includes a descriptive and synthetic analysis against a highly cited taxonomy of cloud computing. The analysis uncovers some imbalances in research and the need for a more granular and refined taxonomy against which to classify cloud computing research using simulators. The paper can be used to guide literature reviews in the area and identifies potential research opportunities for cloud computing and simulation researchers, complementing extant surveys on cloud simulation platforms.


In order to solve the transmission error from the backlash in precision gear transmission, this paper proposes a mechanism which uses slider and pendulum to eliminate backlash.Pro/E is used to create a 3-D model of the new-type gear pair, The imitation experiment by mechinism shows that the new-type gear pair installed auto-eliminate has not interference. Movement is imitated by software,the rate curve and acceleration curve of corresponding points are measured.


This study aims to determine the relationship of each variable, exposure to Tokopedia BTS advertising news (X1), word of mouth exposure (X2) with interest in using the Tokopedia (Y) application. This research uses quantitative research methods. The data collection technique used non probability sampling with a sample size of 50 respondents. The analysis used to test the hypothesis is the Pearson correlation test. Hypothesis testing that has been carried out shows that Tokopedia BTS advertising news exposure with interest in using the Tokopedia application is 0.012 (<0.05) with a correlation coefficient of 0.354, so there is a positive relationship between news exposure and interest in using Tokopedia. The significance result of word of mouth exposure with interest in using is 0.019 (<0.05) with a correlation coefficient of 0.330, so there is a positive relationship between word of mouth exposure and interest in using the Tokopedia application.


The author reports on a study in which 244 student affairs professionals rated the impact of nine situational, institutional, or dispositional barriers on their current participation in development activities.


This study examined the temperature-related piezoresistance issues of p-type doped 3C-silicon carbide (3C-SiC) materials. Previously, we proposed piezoresistance temperature models that describe phenomena based on the ionization energies of materials oriented for high-temperature operations. This study aimed to determine the ionization energy as a function of the aluminum doping concentration of 3C-SiC. However, at the low-temperature region a drastic decrease in the piezoresistive coefficient was observed, and it was predicted to occur when materials possessing large impurity ionization energy are used under negative thermal strained conditions. This phenomenon is in contrast to the conventional piezoresistance factor $P(N,T)$ that is based on narrow band-gap materials such as silicon or germanium; thus, it provides new insights into low-temperature piezoresistance phenomena.


Like Weimar Germany, contemporary Russia is home to fascist actors and widespread nationalism. But unlike interwar Germany, the party system in post-Soviet Russia is heavily manipulated and civil society remains underdeveloped. This means that fascists have not had a chance to use elections or to penetrate civil society in order to build up political support. The continuing presence of a resolutely authoritarian, yet non-fascist "national leader" (Vladimir Putin) keeps the country from becoming a liberal democracy but it also, for now, makes it less likely that the regime will become fascist.


The various sources are generating a lot of polluting materials in the ponds water of Harahi & Gangasagar in the district of Darbhanga in Bihar. The sources are domestic drainagesthat directly discharge night soil from houses, medical wastes from doctor's clinic as well as industrial garbage. It is due to the presence of houses, clinics, some industries near the Harahi and Gangasagar ponds. These wastes are very dangerous and hazardous in nature on one hand, and at the other hand may contain a lot of valuable materials which protect our environment. In view of safety, it is essential to treat these wastes properly to protect the environment. There are various ways by which toxic and valuable by-products can be separated. The toxic products can be properly discarded and valuable products can be effectively utilized. The authors present the physicochemical analysis of Harahi and Gangasagarpond water. The results obtained have been compared with standard values of "Bureau of Indian standard permissible limit for drinking water."


Abstract The effect of molecular oxygen on the broadening and shift of the 535.0 nm Tl line resulting from the photodissociation of thallium iodide vapour was studied at low densities of O2. The broadening and shift coefficients were determined.


Endothelial cell‐selective adhesion molecule (ESAM) is a member of the immunoglobulin superfamily and mediates homophilic adhesion between endothelial cells. ESAM has been shown to bind to membrane‐associated guanylate kinase (MAGUK) with inverted domain structure 1 (MAGI‐1), but the interaction between these molecules remains unknown. We investigated the role of ESAM in the subcellular localization of MAGI‐1 and cell adhesion by means of transfection experiments using Chinese hamster ovary (CHO) cells. Overexpression of ESAM recruited MAGI‐1 to the cell–cell contact area. The intracellular domain of ESAM was necessary for the recruitment of MAGI‐1 to the cell contact area, but did not participate in the initial cell–cell adhesion. Cell dissociation assays revealed that colocalization of ESAM and MAGI‐1 promoted actin polymerization through the postsynaptic density 95/discs large/zonula occludens‐1 (PDZ) domain and resulted in firm cell–cell adhesion, which was inhibited by an actin polymerization inhibitor. When the cells attach to each other, colocalization of ESAM and MAGI‐1 can lead to the actin polymerization at intracellular contacts. Interaction of ESAM with MAGI‐1 activated RhoA, and ESAM‐mediated MAGI‐1 recruitment to the cell membrane and mature cell adhesion were inhibited by a RhoA inhibitor. These findings suggest that ESAM may regulate MAGI‐1 recruitment to the cell contacts, and subsequently promote actin polymerization and mature cell–cell adhesion through a RhoA‐dependent mechanism.


Malignant melanoma of the anorectum is a rare disease that tends to have hematogenic and lymphatogenic metastasis at the early stage. Thus it carries an extremely poor prognosis and treatment is difficult. A 51-year-old man who complained of anal bleeding was diagnosed as having malignant melanoma by barium enema study and colonofiberscopy. It was localized at the anterior wall 3cm oral from the anal verge. He received abdominoperineal resection. After the operation 2 courses of DAV chemotherapy were administered. Consequently, no recurrence has been observed. One hundred and five cases of malignant melanoma of the anorectum have been reported in Japan since Dr. Ezaki reported the first case in 1929. We reviewed and discussed on these 105 cases.


OBJECTIVE
To compare magnetic resonance proton spectroscopic with clinical data and to propose a spectroscopic staging of Alzheimer's disease (AD).

METHOD
Subjects (n = 46), normals (12) and with AD (34), paired to age (CDR0-CDR3); AD diagnosis according to DSM-IV/NINCDS-ADRDA criteria; 1H-MRS with Signa Horizon LX-GE, 1.5T; single voxel at hippocampal region/HCR and posterior cingulate area/PCA.

RESULTS
Statistically significant decrease (p < 0.01) only of Naa/Cr--at HCR among the CDR0, CDR1+CDR2, and CDR3, and at PCA between CDR0 and CDR1+CDR2 in relation to CDR3.

CONCLUSION
The HCR is the first to show Naa reduction (CDR1). The PCA suffers later (CDR3). These values decline progressively according to the severity stages. Considering the disparities between the HCR and PCA it is possible to suggest a spectroscopic (metabolite) staging (MS) of AD, as follows: MS0 (-CDR0) = both normal HCR and PCA, MS1-2 (approximately CDR1-2) = abnormal HCR and normal PCA, and MS3 (approximately CDR3) = both abnormal HCR and PCA. These results make possible the early diagnosis, to follow the degenerative process throughout the course, and to suggest a spectroscopic staging related to the clinical stages of AD.


A computationally efficient polarization-angle-frequency estimation algorithm based on spatial-temporal nested sampling is proposed. Radar cross-sections (RCSs) diversity in multiple CPIs is exploited to construct a virtual polarization-spatial-temporal (PST) manifold with extended degree of freedom. A computational efficient method without eigen-decomposition is derived to estimate K-R signal subspace. Automatically paired polarization, azimuth-elevation angles and doppler frequency estimates are obtained by exploiting the idea of the ESPRIT algorithm.


With general relativity as its foundation, the Standard Model of Cosmology has been developed, a model in which all matter is homogeneously and isotropically distributed throughout the Universe. We ...


We report on the synthesis of cubic-phase garnet-type solid-state electrolytes based on Bi-doped Li7La3Zr2O12 (LLZO). Bi aliovalent substitution of Zr in LLZO utilizing the Pechini processing method is employed to synthesize Li7−xLa3Zr2−xBixO12 compounds. A strong dependence of the ionic conductivity on Bi content is observed, and under our synthesis and sintering conditions, a >100-fold increase over the un-doped sample is observed for x=0.75. Cubic-phase Li6La3Zr1BiO12 compounds are generated upon annealing in air in the temperature range 650 °C–900 °C. In contrast, in the absence of Bi, the cubic garnet phase of Li7La3Zr2O12 is not formed below 700 °C and a transformation to the tetragonal phase is observed at ∼900 °C for this un-doped compound. The role of Bi in lowering the formation temperature of the garnet cubic phase and in the ionic conductivity improvements is investigated in this work. We ascribe the effect of Bi-doping on ionic conductivity increments to changes in Li+-site occupancy and lattice parameters and the reduction in the formation temperature for the cubic-phase formation to rate enhancements of the solid-state reaction. To identify the site occupancy of Bi in the garnet structure, we employ synchrotron extended x-ray absorption fine structure spectroscopy. Our results indicate that Bi additions occupy the Zr-type sites exclusively, to within the accuracy of the measurements.We report on the synthesis of cubic-phase garnet-type solid-state electrolytes based on Bi-doped Li7La3Zr2O12 (LLZO). Bi aliovalent substitution of Zr in LLZO utilizing the Pechini processing method is employed to synthesize Li7−xLa3Zr2−xBixO12 compounds. A strong dependence of the ionic conductivity on Bi content is observed, and under our synthesis and sintering conditions, a >100-fold increase over the un-doped sample is observed for x=0.75. Cubic-phase Li6La3Zr1BiO12 compounds are generated upon annealing in air in the temperature range 650 °C–900 °C. In contrast, in the absence of Bi, the cubic garnet phase of Li7La3Zr2O12 is not formed below 700 °C and a transformation to the tetragonal phase is observed at ∼900 °C for this un-doped compound. The role of Bi in lowering the formation temperature of the garnet cubic phase and in the ionic conductivity improvements is investigated in this work. We ascribe the effect of Bi-doping on ionic conductivity increments to changes in Li+-site occupancy and latt...


Flooding of cemented paste backfill (CPB) filled mine workings is, commonly, a slow process and its rate is important as a rapid flooding could limit sulphide oxidation and subsequent trace metal leaching. CPB-mixtures containing pyrrhotitic tailings with elevated concentrations of trace metals were flooded with different time delays. Delaying the flooding event increased trace metal leaching from CPB-mixtures, but except for copper, it was still lower compared to that in unmodified tailings. Regardless of time for flooding, sulphide oxidation in CPB-mixtures occurred, which poses an environmental risk, whereas a substantial proportion of trace metals was associated with acid-intolerant phases.


The ability to manipulate particles has always been a fundamental aspect for developing and improving scattering and microscopy techniques used for material investigations. So far, microscopy applications have mostly relied on a classical treatment of the electron-matter interaction. However, exploiting a particle's quantum nature can reveal novel information not accessible with conventional schemes. Here, after describing recent methods for coherent wave function engineering, we discuss how quantum manipulation of electrons, He ions, and nuclei can be used to implement low-dose imaging methods, to explore correlated quantum state dynamics in condensed matter, and to modulate nuclear reactions for energy-related applications and gamma-ray lasers.


Hand in hand with the COVID-19 pandemic, new processes were put in place to address such disease. The implementation of a structured and reliable process for swabbing of potential COVID-19 infected patients became critical. Nevertheless, this process did not come without problems in practice. Around mid-March, it was noticed that over 10% of swab samples collected at Hillingdon Hospital were being rejected for analysis. A root-cause analysis through questionnaires and objective data sampling was conducted with support of internal stakeholders to explore the problem. Practical issues in sample handling linked to inadequate communication and training were identified as the main cause for sample rejection. By the third week of March (i.e. one week in the project), an immediate approach was taken. With support from senior nursing staff, the team created an open space during handovers for the discussion of concerns and issues around sampling and technique. Ward specific figures and details were handed over to the ward sisters to inform each team. During the second stage of interventions, in collaboration with several members of the multidisciplinary team, multiple scripts for an educational video were developed. Several video versions were released based on feedback and following updates from national guidelines. With support of Silver Command, the videos were distributed through the daily email communications and in the Trust's homepage. The actions implemented had an immediate effect in the overall sample rejection rate, reaching about 5% a month in the project, and dropping to less than 2% in later months. The project improved communication within the teams and cooperation between the multidisciplinary team, highlighting the importance of continuous professional development. In moments of crisis, this union led to further support and reliability on leadership who was trying to promote safety among staff and patients during this difficult time.


Residual stresses and part distortion are major obstacles to time-to-market, reduced scrap, and high part quality in metal machining. Aerospace monolithic structures suffer from distortions that hamper assembly operations. Automotive powertrain components have high flatnesstolerance surfaces that maintain fuel efficiency while lowering emissions. Problems persist because industry lacks a capability to predict machining induced residual stresses and part distortion. One method of comprehensive distortion analysis is application of the finite element method (FEM). Here, a three-dimensional FEM model is presented that includes fully adaptive unstructured mesh generation, tight thermo-mechanical coupling, deformable tool-chip-workpiece contact, momentum effects at high speeds and constitutive models appropriate for high strain rate, and finite deformation analysis that predicts machining induced residual stresses. A complementary capability to translate the machining induced residual stress results and incorporate pre-existing stresses to a holistic part level analysis for part distortion prediction will be discussed.


The noise and stability of a commercial current source is limited by the quality of components used for construction, such as the voltage reference chips, resistors, and power supplies. A state-of-the-art commercial current source typically exhibits a stability no better than parts in $\pmb{10}^{7}$. In this paper, we present a way to implement a current source with "external" electrical references. This approach allows the current source stability to be decoupled from the noise characteristics of the main power supply circuit. A few parts in $\pmb{10}^{8}$ stability is demonstrated here.


ABSTRACT This qualitative study examines students' perceptions of their bilingualism in a school that is attempting to disrupt inequalities through the promotion of social justice through bilingual/bicultural education. In order to understand students' perspectives of their bilingualism in Arizona's restrictive policy context, the researchers apply Bourdieu's conceptions of habitus, field, and capital. Findings indicate that students view their bilingualism as an asset that provides them with various forms of capital. Additionally, despite the English-hegemonic context of Arizona, this school plays an essential role in promoting students' bilingualism/biculturalism as an avenue to greater possibilities in their lives.


The aim of this paper is to examine what we know about the experience and outcomes of networked initiatives aimed at facilitating practitioner research. We outline the roles and significance of practitioner research within social work; review emerging understanding of practitioner research network initiatives; and draw conclusions from a comparative analysis of three such initiatives in Auckland, New Zealand, Arhus County, Denmark, and across Scotland. We consider the nature and challenges of practitioner research and a number of responses to how such work should be formulated and conducted. Central to our argument is an empirically informed consideration—from our separate and shared experiences—of how well networks enhance the process and consequences, and art and craft, of such research projects.


Testing is one way of validating that the customers have specified the right product and verifying that the developers have built the product right. Traditional testing methodologies such as: path, branch, instruction, mutation, scenario, or requirement testing usually treat all aspects of software as equally important [1], and is often reduced to a purely technical issue leaving the close relationship between testing and business decisions unlinked and the potential value contribution of testing unexploited [2]. Valuebased software testing serves to bridge the gap between the internal software testing process and business value that comes from customers and market [3]. The essential of Value-based software testing is feature prioritization that brings business importance that comes from CRACK key customers, software quality risk from developing team, software testing cost, process estimation and controlling from the testing team, and the external commercial factors, e.g., market pressure from the market into consideration. This decision making process could be seen as a multiple-objective decision making process that tries to maximize the business importance, identify the most risky features, minimize the testing cost and minimize the market erosion. The prioritization strategy could be reflected and influenced by different multiple-objective decision value functions. In [3], a multiplicative multiple-objective value function is used to generate the testing priority ranking. In this paper, we will use additive multiple-objective value function to generate testing priority ranking and compare the result in the end.


The influence of Ca2+ concentration around myofibrillar Mg2+-ATPase on the speed and pattern of rigor mortis in fish species or cultured and wild fish was studied. The change of contraction in pillar form muscle with the lapse of storage time reflected very well the temporal change of gram of tension in muscle of cultured red sea bream. This result showed that the contractile percentage of muscle is very useful on the progress of rigor mortis. The progress of muscular contraction differed among fish species and between cultured and wild fish of the same species, and which were seen in four parameters of rigor mortis: the progressive speed, pattern, and the time and level of peak reached. These four parameters were closely related to one another. The ranking among fishes in myofibrillar Mg2+-ATPase activity was not consistent with the difference of speed of progression of muscular contraction. The progress of superprecipitation reaction of actomyosin in muscle of cultured red sea bream was changed remarkably in four parameters by a very small difference of Ca2+ concentration, coinciding very well with the mutual relation among the four parameters on the progress of muscular contraction. Therefore, it was considered that the difference of the progress of muscular contraction among fish species and between cultured and wild fish can be mainly caused by the difference of Ca2+ concentration around myofibrils.


The present investigation was conducted to determine the genetic variability, heritability and genetic advance for the quantitative characters among the available germplasm of bottle gourd. Thirty six genotypes including two checks (Pusa Naveen and Narendra Rashmi) evaluated in randomized complete block design with three replications during summer 2019. Single row plot of 3 m length spaced 3 m apart with 50 cm plant to plant distance was maintained. Observations were recorded on 14 quantitative traits viz . days to first staminate flower and pistillate flower anthesis, node number to first staminate and pistillate flower appearance, days to first fruit harvest, green fruit length (cm), green fruit circumstances (cm), mature fruit length (cm), mature fruit circumstances (cm), mature fruit weight(kg), seed weight per fruit(g), number of seed per fruit(g), 100-seed weight(g), seed yield per plant(g). The analysis of variance for the design of experiment indicated highly significant differences among the genotypes for all the characters. Based on mean performance of seed yield and yield components, NDBG-517 (189.67), NDBG-19-4 (176.67), NDBG-63-1-1-1 (140), Pusa Santusti (138.48), NDBG-5-1-1 (133) were identified as most promising genotypes for yield and major component traits. High magnitudes of variability (GCV and PCV) were observed for seed yield per plant (41.70 % and 41.53% ) followed by number of seed per fruit(37.02% and 36.67%), 100 seed weight(33.05% and 32.59%) and seed weight per fruit(30.84% and 28.67%). High heritability (broad sense) (>75%) along with high genetic advance in per cent of mean (>30%) were estimated for seed yield per plant (97.21% and 85.20%) followed by number of seed per fruit (98.15% and 74.85%), 100 seed weight(97.21% and 66.19%), seed weight per fruit(86.43% and 54.91%), mature fruit diameter(94.74% and 46.72%), fresh fruit girth(92.66% and 44.65%), node number to staminate (92.18% and 38.48%) and pistillate flower appearance(92.34% and 38.95%), mature fruit weight(78.00% and 31.43%), fresh fruit length (86.60% and 34.90%) and girth(92.66% and 44.65%), mature fruit length(94.01% and 37.98%) and diameter (94.74% and 46.72%).


This paper proposes an autoencoder-based symbol-level precoding (SLP) scheme for a massive multiple-input multiple-output (MIMO) system operating in a limited-scattering environment. By recognizing that only imperfect channel state information (CSI) is available in practice, the goal of the proposed approach is to design the down-link SLP system robust to such imperfect CSI. Toward this goal, this paper leverages the concept of autoencoder wherein the end-to-end communications system is modeled by a deep neural network. By end-to-end training the proposed autoencoder, this paper shows that the downlink symbol-level precoder as well as the receivers' decision rule can be jointly designed in ways that are robust to channel uncertainty. Moreover, this paper introduces a novel two-step training procedure to design a robust precoding scheme for conventional modulations such as quadrature amplitude modulation (QAM) and phase shift keying (PSK). Numerical results indicate that the proposed autoencoder-based framework, either trained by the end-to-end approach in which the receive constellation is a design variable or by the proposed two-step training approach with QAM constellation, can efficiently design a SLP scheme for massive MIMO system which is robust to channel uncertainty.


The Great Wall of China was built as a defence against Barbarians. It is very high, very thick and 1,684 miles long. But the longest, highest, deepest barrier in the world is in Australia. It is a wire mesh fence 6,000 miles long also built to defend the land from barbarian hordes. There are no gaps in this fence. Only a few get through from Down Under. Five who did it alone, banded together, and chose to call themselves what 6,000 miles of fence could not contain. 'Listen to their bite, for you won't hear their bark'.


Journal of Clinical Sleep Medicine, Vol. 14, No. 6 June 15, 2018 A 6-year-old male presents to a sleep clinic for evaluation of abnormal movements during sleep. These movements have persisted unchanged since he was age 1 year. As soon as he falls sleep, he bangs his head repetitively on the pillow or rolls his head side to side all night until the morning. Intermittently, he rhythmically bangs his legs. This occurs on a nightly basis in the prone position. Examples of these movements can be seen in Video 1 and Video 2. If his mother rubs his back, he stops transiently and then resumes. He does not snore. He reports an uncomfortable sensation in his legs and an urge to move his legs in the evening that worsens prior to falling sleep. Walking SLEEP MEDICINE PEARLS


This paper explains the design and simulation of a conditioning circuit based on a current-mode mixed analogue-digital adaptive processor. The proposed processor model consists of two main blocks: a D/A four quadrant multiplier and a current conveyor that performs the non-linear output function. Applied to sensors conditioning, the processing system customizes its free parameters, stored in digital registers, adapting the response. System simulation results and achieved performance are presented.


Abstract Background: Metabolic abnormalities observed with atypical antipsychotic treatment may be specific to each antipsychotic medication. The association between atypical antipsychotics and risk factors for cardiovascular disease prompted the American Diabetes Association (ADA) and the American Psychiatric Association (APA) to issue a consensus statement that categorized aripiprazole and ziprasidone as atypical antipsychotics with a lower likelihood of metabolic abnormalities. Objective: The aim of the current systematic review was to evaluate real-world studies (i.e. observational/naturalistic and open-label studies) assessing the risk for weight gain, dyslipidemia, glucose abnormalities, and diabetes mellitus in adult patients receiving treatment with atypical antipsychotics, with a specific focus on aripiprazole. Methods: A systematic PubMed search for articles published between 1 January 2000 and 4 October 2011 was performed using the following search terms in the title and abstract: aripiprazole, atypical, glucose, insulin, cholesterol, triglycerides, diabetes, hemoglobin A1c, weight, body mass index, and hyperlipidemia. Results: Twenty-two peer-reviewed articles were found that assessed the metabolic effects associated with aripiprazole treatment, including studies from small observational trials to large databases (n = 15 to n > 1,700,000). Thirteen articles reported observational or naturalistic studies, and nine were open-label trials evaluating weight gain, dyslipidemia, glucose abnormalities, and the risk of developing diabetes in adult patients receiving treatment with aripiprazole. Compared with other atypical antipsychotics, aripiprazole was either less likely to have an impact or had a comparable impact on weight gain and dyslipidemia; the degree of effect appeared to be dependent on study design. In addition, there was less risk of diabetes mellitus with aripiprazole compared with most other atypical antipsychotic agents. Conclusions: Consistent with data from randomized controlled studies, the current review of observational/naturalistic and open-label studies suggests aripiprazole may be associated with a lower risk than other commonly used atypical antipsychotics for metabolic adverse events in adults, consistent with the ADA/APA consensus statement.


A new particle tracking algorithm is derived based on consolidated methods, with the aim of overcoming the current limits encountered with high particle density flows. The proposed method consists of an integration of the relaxation algorithm based on matching probabilities into vision-based features association concepts. Hybridization with PIV pre-analysis is suggested to help with the estimation of parameters. A dual calculation strategy is also developed in order to reduce the amount of spurious vectors. Simulation tests using synthetically generated images are carried out to evaluate the sensitivity of the proposed method to the particle image density, the background noise and the nature of the flow. Three flow configurations with a growing degree of complexity are successively considered: a 2D flow over a moving wall, a steady 2D Lamb–Oseen vortex ring, and a 3D unsteady homogeneous isotropic turbulence. The ability of the new tracking algorithm to provide better matching performances with high reliability than conventional techniques, out of a dense particle image field, is demonstrated.


The aim of this research work was to isolate microbes from soil, to investigate their potential use as effective bioremediation tools for trichloroethylene—a potent environmental pollutant. The isolate showing good growth in presence of TCE was named PM102. Microbiological characterisation of the PM102 isolate showed that it was a gram negative rod. Detailed structure was revealed by scanning electron microscopy. pH and temperature optima, salt tolerance and optimum TCE concentration for growth of PM102 were determined. The ability of this bacterium to degrade TCE was studied in acidic and neutral pH by biochemical test and chloride release. Five TCE inducible bands were detected in the protein profile of the isolate as studied by SDS PAGE. A major TCE inducible band of 51.61 kDa was excised from the gel and injected into rabbit to raise specific antibody. The bacterium was identified as Stenotrophomonas maltophilia PM102 by 16S rDNA amplification and sequencing. The 16S rRNA gene sequence has been deposited in the NCBI GenBank with accession number JQ797560. This genus has not been described previously as being capable of TCE degradation. We report for the first time a Stenotrophomonas sp. that grows on TCE as the sole carbon source.


This study examines the pattern of returns and volatility on Irish equity markets, over a period when the markets were deregulated. GARCH and GARCH-IN-MEAN models are applied to data from three study periods. Volatility spillovers from the London stock market are considered, providing a test for evidence of a change in the degree of this influence. Within sample results show that GARCH models do provide a useful description of Irish equity returns. Furthermore, the inclusion of external volatility improves the model fit. There is no evidence that deregulation coincides with an alteration in the impact of external volatility. Forecast results indicate some evidence that the inclusion of external volatility spillovers does improve the forecast accuracy of GARCH models. Tests indicate that a GARCH-IN-MEAN specification does not suit Irish equity data.


MATLOC is a nonlinear, transient, two-dimensional (planer and axisymmetric), thermal stress, finite-element code designed to determine the deformation within a fractured rock mass. The mass is modeled as a nonlinear anistropic elastic material which can exhibit stress-dependent bi-linear locking behavior.


At present, the oxaliplatin-cetuximab combination therapy has attracted the attention of some largescale clinical trials and basic experiments. Here this mini-review is to elaborate synergism or antagonism mechanism of their co-application from the perspectives of cell cycles, apoptosis, repair of DNA damage and reactive oxygen species formation. The molecular biomarkers to predict combination effect of the two drugs is also discussed.


We introduce an estimator for the population mean based on maximizing likelihoods formed from a symmetric kernel density estimate. Due to these origins, we have dubbed the estimator the symmetric maximum kernel likelihood estimate (smkle). A speedy computational method to compute the smkle based on binning is implemented in a simulation study which shows that the smkle at an optimal bandwidth is decidedly superior in terms of efficiency to the sample mean and other measures of location for heavy-tailed symmetric distributions. An empirical rule and a computational method to estimate this optimal bandwidth are developed and used to construct bootstrap confidence intervals for the population mean. We show that the intervals have approximately nominal coverage and have significantly smaller average width than the corresponding intervals for other measures of location.


Specific reactions to the Heppner and Anderson, Keeney and Morris, and Gelso articles are offered. Also, some general thoughts on counseling research are provided.


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We have identified four cDNA clones, cl‐1, cl‐5, cl‐15, and cl‐16, that represent genes induced by serum in resting mouse 3T3 cells. Partial sequence analysis of the four cDNAs indicated that cl‐15 corresponds to the mouse beta‐actin gene. Comparison of the DNA sequences of the other three clones with the sequence data bank (Genbank) showed little homology to other known DNA sequences and thus represent novel genes. The level of the mRNAs corresponding to the four genes began to increase in resting cells following serum stimulation, reached a peak between 5 h and 8 h and then started to decline. Inhibitors of transcription diminished the induction of the mRNAs corresponding to the four genes. Cycloheximide and anisomycin hadlittle effect on the induction of beta actin mRNA while the induction of the other three genes was suppressed by the same inhibitors. 12‐O‐Tetradecanoylphorbol‐13‐acetate and the calcium ionophore A23187 enhanced the expression of the cl‐16 mRNA while epidermal growth factor, fibroblast growth factor, or insulin enhanced the expression of cl‐1‐ and cl‐5‐specific transcripts. The level of beta‐actin mRNA was elevated in resting cells by epidermal growth factor and 12‐O‐tetradecanoylphorbol‐13‐acetate and to a lesser extent by fibroblast growth factor, insulin, and dibutyryl cyclic AMP‐elevating agents. Pertussis toxin, an inhibitor of the action ofG proteins, did not significantly suppress the activation of the four genes by serum. However, 2‐aminopurine, a protein kinase inhibitor, suppressed the induction of the four transcripts in serum‐stimulated cells. The possible pathways involved in the activation of these genes in resting cells are discussed.


McGrath® MAC video laryngoscope (McG) has been used for orotracheal intubation in both normal patients and patients for whom intubation was expected to be difficult, and has been reported to provide improved visibility of the glottis during tracheal intubation. There are some reports that normal nasotracheal intubation is easier with McG than with macintosh laryngoscope (ML). The usefulness of McG for nasotracheal intubation is beginning to be recognised. We experienced three cases using McG in patients for whom intubation was expected to be difficult due to the limited mouth opening and using McG for those patients enabled smooth nasotracheal intubation. McG provides good visual field during nasotracheal intubation, and is less invasive to the patient.


The action is an expression of personal individualities,also is a kind of language to convey personal ideas or feelings.Classical novel Water Margin was good at describing personages in their action,effected vivid touch to see them in the action,and characterized successfully a series of art images of lifelike heroes of Liang Mountain.The description about personal action in Water Margin had bright artistic characters.Vivid description about personal action was an important form to express personal individualities and to portray artistic images.


New Vision for Education, to examine the pressing issue of skills gaps and explore ways to address these gaps through technology. Academic institutions are shortly drawing attention in Active learning methods for making effective learning style, for identifying learner's achievements and demand, for tracing academic progress and besides for performance. People's increased confidence for accountability and transparency makes it imminent to enforce big data analytics in the educational institution. Analytics can be defined as the process of determining, assessing, and interpreting meaning from volumes of data. Educational institutions are instantly illustrating acceptance in finding methods for making operative learning process, for classifying learner's Strength and weakness, for outlining academic activities and also for predicting student future performance. Being a arch democracy, India is further trying to join this know backwards and forwards learning era. This paper will explain educational technology trends revealed that roughly can be done to develop higher-order competencies and character qualities in Education sector. It also concentrate technologies with Active learning objectives and to develop learning approaches that efficiently and comprehensively deploy technology throughout the stages of proposition and learning.


By a series of amelioration to the process technique of diesel oil-box and its valve seat, to reduce obviously the faults of oil-leakage seepage and improve evidently the surface quality and rustproof ability of oil-box, whilst also control effectively the ration of unqualified products during machining and save the cost comparatively.


Article 434.1. of the Civil Code of the Russian Federation considers the misconduct during contract negotiationsto be the basis for civil liability in the form of losses compensation. However, the legislator does not define the concept of bad faith and its place among the constituent elements of the violation of law, which in the Russian legislation, doctrine and legal practice is traditionally recognized as the basis for liability. The purpose of this article is to address the task relevant for the development of Russian civil law and law enforcement practice: to determine the nature of bad faith of the party in the course of or failure of contract negotiations, its relation to culpability as a condition for the traditional civil liability. The research allows to conclude that bad faith of the party during negotiations cannot be an independent condition (element) of an offense. The article gives a critical analysis of the Resolution No. 7 of the Supreme Court Plenum "On application by the courts of certain provisions of the Civil Code on liability for breach of obligations"dated March 24, 2016, in the part of clarification of the rules on the conditions of civil liability under Article 434.1. of the Civil Code.


The invention discloses high-resolution code-spraying printing ink comprising the following components by weight percent: 6 to 12 percent of polyacrylate, 2 to 6 percent of vinyl, 1 to 3 percent of polyurethane, 2 to 5 percent of dye, 2 to 6 percent of high molecular stabilizing agent, 0.1 to 0.5 percent of conductive agent, 0.2 to 0.5 percent of auxiliary agent and 75 to 86 percent of solvent. The preparation process of the high-resolution code-spraying printing ink comprises the following steps of: firstly, adding the dye into a high molecular stabilizing agent solution for full dissolving and acting, then adding other various resin solutions and finally, adding various conductive agent solutions and various auxiliary agent solutions to obtain a finished product after substantial stirring and filtering. The invention enhances the adhesion force, the resolution and the fineness stability of the printing ink greatly by carrying out innovative design and synthesis on a main resin and dye stabilization system of the printing ink.


Concurrent strain gage and pressure transducer measured flight loads on a lifting reentry vehicle are compared and correlated with wind tunnel-predicted loads. Subsonic, transonic, and supersonic aerodynamic loads are presented for the left fin and control surfaces of the X-24B lifting reentry vehicle. Typical left fin pressure distributions are shown. The effects of variations in angle of attack, angle of sideslip, and Mach number on the left fin loads and rudder hinge moments are presented in coefficient form. Also presented are the effects of variations in angle of attack and Mach number on the upper flap, lower flap, and aileron hinge-moment coefficients. The effects of variations in lower flap hinge moments due to changes in lower flap deflection and Mach number are presented in terms of coefficient slopes.


An aqueous extract of human placenta, used as wound healer, shows stabilization of trypsin against autodigestion as one of the peptides of the extract binds very strongly with the protease. Trypsin retains 40% of activity at constant level between 20 and 26 days in presence of the extract against complete inactivation in its absence. Inhibition of esterolytic activity and inability to react with p‐nitrophenyl‐p'‐guanidinobenzoate, HCl, an active site directed reagent, by trypsin in presence of a peptide fraction of the extract indicated blocking of the catalytic site of the enzyme. Rayleigh scattering, size‐exclusion HPLC, fluorescence resonance energy transfer, and surface plasmon resonance show that fibronectin type III‐like peptide present in the extract interacts with trypsin. The peptide–trypsin complex is dissociated in presence of high concentration of substrates. Thus, regulation of trypsin activity by the placental extract is evident. J. Cell. Physiol. 226: 2033–2040, 2011. © 2010 Wiley‐Liss, Inc.


Hydrocarbon traps in the Philippine Islands developed during a long, complex history of microplate tectonics. Carbonate and clastic stratigraphic traps formed during Mesozoic and early Cenozoic rifting and drifting. Hydrocarbons, generated in deep rift basins, migrated to the traps during drifting. Later Cenozoic compressional tectonic activity and concomitant faulting enhanced some traps and destroyed others. Seismic data offshore from Palawan Island reveal the early trap histories. Later trap histories can be interpreted from seismic, outcrop, and remote-sensing data. Understanding the microplate tectonic history of the Philippines is the key to interpreting trap histories.