Objective:To summarize successful experience in Deutsches Herzzentrum Berlin for long-term circulation support with two different left ventricular assist devices.Method:Clinical data of spatients received implantation of left ventricular device as long-term support were analyzed.The indication and complications of ventricular assist device as destination therapy were reviewed briefly.Result:Sixty-nine patients received long-term mechanical circulation support.Among them,five 5 patients (4 male,1 female,the with average age was 57.2 years old) were supported over 4 years with good quality of life.Conclusion:Left ventricular assist device as destination therapy is was a good alternative for non-transplant candidates.


The large AD 1258 eruption had a stratospheric sulfate load approximately ten times greater than the 1991 Pinatubo eruption. Yet surface cooling was not substantially larger than for Pinatubo (∼0.4 K). We apply a comprehensive Earth System Model to demonstrate that the size of the aerosol particles needs to be included in simulations, especially to explain the climate response to large eruptions. The temperature response weakens because increased density of particles increases collision rate and therefore aerosol growth. Only aerosol particle sizes substantially larger than observed after the Pinatubo eruption yield temperature changes consistent with terrestrial Northern Hemisphere summer temperature reconstructions. These results challenge an oft‐held assumption of volcanic impacts not only with respect to the immediate or longer‐term temperature response, but also any ecosystem response, including extinctions.


s, the Bibliography of Agriculture, Index Medicus, and the information programs of the National Library Mr. Shank is Assistant Librarian, University of California, Berkeley. of Medicine, the Armed Services Technical Information Agency, and the Office of Technical Services.1 The value of these activities to academic research libraries is not unimportant, but it is not within the scope of this article. No matter how little the federal government budget seems presently to provide as direct dollars for operation of academic libraries, the indispensable role of federal funds in these other activities, which ultimately are so essential to American librarianship, cannot be denied. Data for the study came from three sources: (1) a survey of about forty-five academic institutions, particularly those participating in the programs of Title VI of the National Defense Education Act; (2) government documents and reports; and (3) a variety of personal sources, including the Washington office of the American Library Association. There is no guarantee that some amounts have not been counted twice, although reasonable care has been made to avoid duplication. There are more likely to be gaps, since the sources of money for library activities are frequently obscure, even to the librarians who spend them. Various provisions of the National Defense Education Act are obvious sources of federal funds for academic libraries. Title IV provides that about one half of the funds of National Defense fellowships "appropriated go to the participating institutions in support of the approved new or expanded programs. 1Federal Funds for Science X: Fiscal Years 1960, 1961, and 1962 (Washington: National Science Foundation, 1961), p. 47. 514 C O L L E G E A N D R E S E A R C H L I B R A R I E S These funds may be used to add members to the faculty, strengthen library acquisitions, or buy laboratory equipment. In academic year 1960-61, about $6 million [was paid] to participating graduate schools."2 Title VI (Language and Area Centers) provides that approximately 50 per cent of the funds are for "administration of the Centers' use (not purchase and installation) of language laboratories, library acquisitions, and employment of pertinent library personnel, grants for staff travel to foreign areas and cost of travel for foreign visiting scholars."3 Most of the funds from these two titles are being spent by the faculty departments involved, and do not add directly to the general library activities of the campuses. The survey uncovered almost two hundred seventy-four thousand dollars of NDEA money, however, being used for personnel ($87,000) and library materials ($187,000) by university libraries. The librarians had little to do with deciding program content or size; this was left to faculties and university administrators. In many instances, the librarians were not even aware such money was available until it turned up in their appropriation ledgers. An attempt was made to add aid to academic libraries to the National Defense Education Act renewal legislation in 1961, but, along with a number of other riders, this was stripped from the proposal and the Act was refueled for two years at its then-attained level. T h e provisions of this rider have been taken over into the omnibus legislation to be mentioned shortly. The National Science Foundation is a source of a limited but growing amount of money to support academic library activities. It is not National Science Foundation policy to finance library operations directly. National Science Foundation facilities-modernization 2 Report on the National Defense Education Act: Fiscal Year Ending June 30, 1960 (Washington: U. S . Department of Health, Education, and Welfare, Office of Education, 1961), p. 14. 3 Ibid., p. 24. grants may be used to refurbish research plants which might include library space. "Library space should compete on its merits with the other space involved in the proposal and a final decision made on the basis of what is most essential to facilitate the research being conducted or envisaged at the facility."4 Proposals totaling over two and twotenths million dollars to support library facilities were submitted in fiscal year 1962. Grants have been made of approximately three hundred and eightythree thousand dollars for departmental library and reading room renovations to fifteen institutions. More is coming from this source, however. T h e Department of Commerce's Office of Technical Services recently established twelve regional technical report centers, eleven of them in academic libraries. The National Science Foundation has guaranteed to finance the operation of these centers, at least in their initial stages of development. T h e foundation may supply as much as one hundred and fifty thousand dollars a year for this activity. The foundation has given a subsidy of ten thousand dollars to another institution for a photocopying service in support of scientific activities. The National Science Foundation could directly affect the use of funds in academic libraries by assisting in the establishment of research units in individual libraries or through an association to study problems of library operations. The federal government is also involved in supplying cash directly to its own institutions of higher learning or those for which it has accepted an administrative obligation. These are the military service schools and a university located in Washington, D. C. which are being supported in the amount of about one and three-tenths million dollars per year. * Letter to author dated 3 May 1962 from H. E . Page, head. Office of Institutional Programs, National Science Foundation. N O V E M B E R 1 9 6 2 515 The federal government's involvement in securing library materials for academic institutions must be counted as a major source of support. Of the 592 depository libraries in existence, 352 are in academic institutions. Most of them take more than half of the material offered on deposit. In fiscal year 1962 the federal government budgeted $573,000 for the deposit of six million documents. Assuming that academic and other depository libraries have similar selecting policies, the documents deposits are worth $338,000 in book money to academic libraries. T h e cost to the libraries varies from eight to one hundred ninetythree dollars per library for postage. The new depository law, among other things, (1) provides for the designation of new depository libraries, most of which will probably be in academic institutions; (2) makes available with some exceptions all government publications including the non-GPO printed documents; and (3) permits the establishment of regional depository libraries. The total value of the documents added to libraries will be over five hundred thousand dollars more than at present, or about two thousand dollars per depository. Public Law 48 activities produced Indian government documents for three academic institutions in the United States (including the Midwest Interlibrary Center) for a period of five years. The cost to the government was seventyfive thousand dollars. The Dingell Amendment to Public Law 480 (Agricultural Trade Development and Assistance Act) among other things makes it possible for the Library of Congress to acquire foreign books, periodicals, and other materials and to deposit them in libraries and research centers in the United States. A portion of the funds held in foreign countries from the sale of commodities under the terms of the law are available for this program. These funds, however, are not automatically available; the U. S. Treasury must declare the funds to be surplus to the normal needs of the United States, and Congress must appropriate them for various purposes just as they do other funds. Late last year the librarian of Congress was appropriated four-hundred thousand dollars for a program for collecting publications overseas. Although several score countries are involved in Public Law 480 activities, sufficient credits have accumulated in only nine of them to the extent that the Treasury can declare that surplus funds exist. The librarian of Congress chose to run a trial program in three of these countries: India, Pakistan and the United Arab Republic. Ten libraries, nine of them academic, are receiving materials from the United Arab Republic. Eleven academic libraries are receiving materials from India and Pakistan. Each of the participating libraries is volunteering five hundred dollars to help pay for the program; all are sharing the salary costs of catalogers to process the material. The fiscal year 1962/63 appropriation bill for the legislative branch of government, including the Library of Congress, was approved by the House of Representatives on April 11, 1962. Six hundred seventy-eight thousand dollars was provided for the Public Law 480 program. The House Appropriations Committee thought the contribution by the benefactor or research libraries "commendable" but wants them to work out a more reasonable, sustained plan for financial participation. The Senate may recommend the appropriation of additional soft currency when the bill is reported. The Library of Congress has decided to restrict its operations for the immediate future to the three nations already involved, and to obtain data on which to base budget requests in future years in other countries where surplus funds are available. Since the selection of libraries to include in the survey of this study does not 516 C O L L E G E A N D R E S E A R C H L I B R A R I E S have a valid basis, an examination of the details of the survey can only give a sense of the availability of federal government funds for academic libraries. Briefly these are the results of the survey. About one hundred seventy-three thousand dollars were given directly to academic libraries by federal government agencies. Three hundred twenty-two thousand dollars came to the libraries directly via othe


The dependence of different optical parameters such as refractive index (n), optical absorption coefficient (a), slope of Tauc plot (C), optical band gap (E/sub G/), dispersion energy (E/sub d/), average excitation energy (E/sub 0/), static refractive index (n/sub 0/) on hydrogen content is reported in this paper. It was found that these parameters significantly depend on hydrogen concentration in LPCVD amorphous silicon films.


4HIS PAPER DESCRIBES A HYBRID ")34 SOLUTION FOR TESTING SYSTEMS ON CHIP WHICH COMBINES PSEUDORANDOM TEST PATTERNS WITH STORED DETERMINISTIC TEST PATTERNS ! METHOD IS PROPOSED TO FIND THE OPTIMAL BALANCE BETWEEN PSEUDORANDOM AND STORED TEST PATTERNS TO PERFORM CORE TEST WITH MINIMUM TIME AND MEMORY WITHOUT LOSING TEST QUALITY 4WO ACCURATE ALGORITHMS ARE PROPOSED FOR FINDING THE OPTIMAL TIME MOMENT TO STOP PSEUDORANDOM TEST GENERATION AND TO APPLY STORED PATTERNS 4O SPEED UP THE OPTIMIZATION PROCEDURE A METHOD IS PROPOSED FOR FAST ESTIMATION OF THE EXPECTED COST FOR DIFFERENT POSSIBLE SOLUTIONS WITH VERY LOW COMPUTATIONAL COST %XPERIMENTAL RESULTS HAVE DEMONSTRATED THE FEASIBILITY OF THE PROPOSED APPROACH FOR COST OPTIMIZATION OF HYBRID ")34


1IL.I Fi .I2 FIC, 1. CIaoSS SECTION (LeA lPORTION OF[r[lit ROOr OF AS HUANSUn7UPPE'R LiAT t.ER IaNiISOR TOO)(Ti -uPoN tiiiCii Riscs [IroN HAD 131 EN PERFORMNII ) .1, cut surface of the root. 1B, fibres of peridental membrane blending with gianulomiiatous tissue. C, old cementum. TC, torn cenmentum, with normal peridental tissue occupying space caused by tear. Et, torn cementum attached to old cementum. FIG. 2. INLJARGEL\INT OLF A. PART OF FIG. 1 A, cut surface of root. C, old cementum. IC, torn cementum. P, peridental tissue occupying space cause(l liy tear. E3, torn cemenitum attachedT to old cementum.


In 1988 and 1990 screening for HbA1c and albumin excretion rate (AER) in diabetic children was carried out throughout Denmark. Each study included about 1,000 diabetic patients and found HbA1c and insulin requirements increased during maturation in both sexes. No significant differences in HbA1c were seen among adolescents treated with two, three or more daily insulin injections. The prevalence of persistent microalbuminuria was 4.3% which was associated only with age and diastolic blood pressure. An international survey on HbA1c and insulin treatment, involving 2,873 children, showed HbA1c to vary significantly between centers. Severe hypoglycemia was related to younger age (0–8 years) and lower HbA1c. Of the children on twice and three times daily injections, 37% used a premixed form of insulin. Very young children were treated with a higher proportion of long-acting insulin. Among adolescent boys, lower HbA1c was related to the use of more short-acting insulin. The data confirm that current treatment of childhood diabetes is inadequate.


Introduction. Two-dimensional (2D) crystals, or layered crystals composed of one or several atomic layers, such as graphene have recently attracted much attention because of its unique mechanical properties. The mechanical properties of single-layer and a few layered 2D materials have been studied both experimentally(1) and analytically(2) . 2D crystals have high rigidity in the in-plane direction, but the bending rigidity in the out-of-plane direction is extremely small(1). Multi-layerd 2D materials are the threedimensional materials constructed by stacking many 2D crystals through weak interactions such as van der Waals force. The mechanical properties of multi-layered 2D materials are dominated by thoes of each 2D crystal and the interaction between the layers. The loose bonding between the layers allows easy shear deformation between the layers, which may lead to an interesting mechanical property where the multi-layered 2D crystals have both high strength and flexibility. In this study, we focus the bending characteristics of multilayered 2D materials. We developed an experimental method utilizing a cantilever bend specimen for evaluating the bending characteristics of multi-layered 2D materials and evaluated the bending properties of a micrometer-sized multi-layered graphene.


The Alzheimer's Association International Conference held its sixth Satellite Symposium in Sydney, Australia in 2019, highlighting the leadership of Australian researchers in advancing the understanding of and treatment developments for Alzheimer's disease (AD) and other dementias.


Investment is an important thing to do given the uncertainty in the future. Babakan Village is located in a position that makes it easy for people to be tempted to shop because of easy access to shopping centers. Through the PKK Mobilizing Team which is a government partner as well as a social organization that functions as a facilitator, planner, executor, as well as controller and with the aim of improving the welfare of the community, this PKM is held by providing counseling on the fundamentals of investment. PKM was attended by approximately sixty (60) participants of PKK ladies, the Secretary of the Village of Babakan and student representatives. This PKM has succeeded in fostering the enthusiasm and curiosity of participants to get to know the types of investments that are safe and can be done Key words: investment; PKK; investment risk; Babakan-SetuKeywords


This paper firstly points out that SVAR model has been popular in the study of transmission of monetary policy in recent years. Therefore, we make a detail presentation of the SVAR model and its deduction process and then carry out the comparative study of the SVAR model in the following fields: the impulse response to a monetary policy shock, the best indicator for monetary policy, and the effectivess of the monetary policy. Finally we think that the SVAR model can find a wide application in Chinese monetary policy study.


Aim: To evaluate the accuracy of Invisalign treatment through the ClinCheck measurements. Materials and methods: A total of 41 patients were considered (11M, 30F), mean age 33 years old, treated with Invisalign. There were evaluated: upper and lower incisor crowding, middle line, mean duration of treatment, N° of aligners, reasons of finishing phase and IPR required. Inclusion criteria: upper or lower dental crowding with aesthetic requirement. Exclusion criteria were the need of surgery and syndromes associated with oral-facial malformations and several malocclusion. Analysis were conducted through the ClinCheck virtual measurement at the beginning (T0) and the end (T1) of treatment. Results: T-test were used for the analysis. T0-T1 results showed an improvement of the values analyzed: T1 complete resolution occurred in 56% for the upper dental arch and 32% in the lower. Conclusion: ClinCheck Invisalign is predictable for the complete resolution of anterior dental crowding, 86% (N°=116) in the upper arch and 80% (N°=108) in the lower arch.


A curriculum recording system comprises a teacher terminal, a student terminal, a host, a mobile data center, and a client, wherein the teacher terminal, the student terminal and the host are connected with each other through a network, the host is connected with the mobile data center through a mobile private network, and the client is also connected with the mobile data center through the network. The curriculum recording system of the present invention can achieve simultaneous display between mobile terminals, and both answers and corrections can be seen in real time, thereby greatly improving examine efficiency; in addition, the curriculum recording system also can achieve on-site explanation and question answering, and parents of a student can watch an interactive video between a teacher and the student through the client.


The investigation of a Lewis base catalyzed asymmetric allylic amination of Morita–Baylis–Hillman carbonates derived from isatins afforded an electrophilic pathway to access multifunctional oxindoles bearing a C3-quaternary stereocenter, provided with good to excellent enantioselectivity (up to 94% ee) and in high yields (up to 97%).


The adrenergic receptors in the isolated feline middle cerebral artery were characterized pharmacologically using a sensitive system for recording circular contractions in vitro. Epinephrine. norepinephrine, isoproterenol. and phenylephrine contracted the vessel in the mentioned order of potency. Together with the inhibitory patterns obtained with graded doses of piperoxan (reversible competitive inhibition) and dibenamine or phenoxybenzamine (irreversible competitive inhibition), these results showed that the contraction was mediated by alpha receptors. With piperoxan and norepinephrine, the mean value for pA2 was 7.06 and for KH1.24 × 10−7M. The mean value for KA calculated for norepinephrine before and after partial irreversible blockade of the alpha receptors with phenoxybenzamine was 1.73 x 10−6M. The norepinephrine response was not directly proportional to the amount of receptors occupied; ED50 was reached when only about 11% of the receptors were occupied and the EAm response was obtained when 75% of the receptors were occupied. Dilation was achieved only after an active tonic contraction had been induced (with 5-hydroxytryptamine) in the vessels, and the order of potency was isoproterenol > norepinephrine - epinephrine > terbutaline. Inhibition with INPEA and propranolol was competitive, as confirmed by Arunlakshana-Schild plots, showing that the dilatory response was a beta-receptor effect. The values for pA2 (8.78 and 9.17) and KH (2.31 × 10−9M and 1.77 × 10−9M) for propranolol were indistinguishable in tests with terbutaline and isoproterenol, respectively. Comparison of the relative potencies of norepinephrine and epinephrine as well as isoproterenol and terbutaline suggested that the receptors were of the beta1 type.


: The aviation industry has now reached considerable heights: there is a growing need to build aircraft to meet the needs of an increasingly mobile public seeking quick and easy ways to get around the world. As passenger numbers rise, so do the numbers of airlines and airports that are providing the fastest mode of transport for the travelling public. In addition to this, there is a growing need to hire employees in this field - flight attendants, air traffic controllers, pilots, etc.., and this fact demonstrates the importance and significance of the aviation sector, which has remained undervalued in recent times. This study aims to identify the problems in the teaching of English in aviation. Because of the large amount of terminology and special phrases that are used in aviation English, we have attempted to analyse and identify what students should focus on vocabulary development as well as to identify the main problems in learning it.


I review a class of models for longitudinal data, showing how it may be applied in a meaningful way for the analysis of data collected by the administration of a series of items finalized to the educational or psychological measurement. In this class of models, the unobserved individual characteristics of interest are represented by a sequence of discrete latent variables, which follows a Markov chain. Inferential problems involved in the application of these models are discussed considering, in particular, maximum likelihood estimation based on the Expectation-Maximization algorithm, model selection, and hypothesis testing. Most of these problems are common to hidden Markov models for time-series data. The approach is illustrated by different applications in education and psychology.


Our experience is presented in performing arthroscopic partial menisectomy for the treatment of 130 knees for the medial osteoarthritis.The patients were 39 men (42 knees) and 83 women (88 knees), and aged 39 to 83 years old (the mean: 64.3 years old). The follow-up period ranged from six months to three years and three months (the mean: one year and six months).We used the Hokudai classification for the roentgenographic classification, and the partly modified Fujisawa's classification for the arthroscopic grade. The comparative investigation of pre-and post-operation was conducted applying the scoreing of JOA knee evaluation in each of the following items: the roentgenographic stage, the grade, FTA. The good result was obtaind in the mean score in all cases, which was increased from 72.5 in preoperative score to 84.3 in post-operative one. The significant improvement was obtained in stage I and II but no significant difference in stage III and IV because the scores were sporadical. As the grade was advancing, the obtained score was decreasing in meniscus and especially in articular surface with the marked tendency.


International capital markets tend to be characterized by volatility, which is always a function of world economic and political environment and is frequently associated with contagion risk and increased cross-market linkages. This phenomenon affects both developed markets and emerging markets, and, being integrated in the context of international financial markets through the globalization process, Romanian capital market could not avoid external influencing factors amplificated by economic recession. We have analyzed the the influence of the international capital markets on the evolution of Bucharest Stock Exchange during 2007-2011 in two separate periods (during the 2007-2009 crisis and after the crisis), using correlation analysis and Granger causality tests on daily data. Our main interest was to see if and how the behavior of the Bucharest Stock Exchange was different during the crisis and after the crisis and how the volatility of the Romanian market changed in the post crisis period. Our results confirmed the high degree of interconnectivity between financial markets revealed by general theory, showing that there was a high degree of correlation between the Romanian stock market and international markets during the 2007-2009, but afterwards the intensity of this correlation slightly declined. Another conclusion was that during the whole 2007-2011 period there was a clear one-way causality induced from the international capital markets towards Bucharest Stock Exchange.


The different approaches to artificial intelligence in Japan and the United States, as connected with the national characters of these two countries, are examined. The state of the art of information processing in Japan is reviewed, with attention given to character recognition, picture and image processing, robot vision, speech recognition and synthesis, machine translation, and speech translation. Research themes for the development of an automatic speech translation telephone system are considered.<<ETX>>


In this paper we emphasize the importance of unique certified one-time key pairs in Buyer-Seller Watermarking (BSW) protocols. We distinguish between reactive unbinding attacks, in which the seller reacts to illicit file sharing by fabricating further evidence of such activity, and pre-emptive unbinding attacks, in which the seller gains an advantage by taking action that pre-empts the file being shared. We demonstrate the importance of certified one-time key pairs in the BSW protocol by Lei et al., for protecting against pre-emptive unbinding attacks, and subsequently reveal a new attack on a recently published BSW protocol due to its omission of unique key pairs.


K is paper addresses the relationship between environmental politics and the public sphere. K e focus is placed on the concept of the "green public sphere", developed by Douglas Torgerson and very in uential in green political theory. I argue that we should rethink Torgerson's twin conceptions of environmental politics and the green public sphere. First, I review Torgerson's Arendtian notion of the public sphere and explain why this view is limited as far as a transformative environmental politics is concerned. Drawing on the functions of public spheres in democratic theory, I stress that the merits of the green public sphere are to be evaluated not only in relation to the type of interaction they facilitate (rational-discursive), but especially to the extent that it is critical with power and in uential on society and democracy. K en, I delineate an alternative account of the green public sphere better suited, in my opinion, to unfold its democratizing aspirations. To this end, I take into consideration Habermas' notion and the further intellectual reactions it provoked.


Optimal growth problem is an important optimization problem in the theory of economic dynamics. This paper provides an overview of the main approaches used in the existing literature in solving infinite horizon discrete time optimal growth problem and includes very recent developments.


Aims: This study investigated the attitude and intention of experts in Agriculture Organization of Fars and Khuzestan Provinces towards the usage of variable rate irrigation technology. Study Design: Cross-sectional study.


The work here presents an abnormal EEC simulation by using the electrophysiological model of the neuron. The spike wave and the multi-spike wave of the EEG morphology are reconstructed. The simulation model is derived from the Chay model, which describes the abnormal process in an excitable neuron via bifurcation. The abnormal process, that spiking can be transformed into bursting rapidly, can be observed in some disorder of the nerve system, such as epileptic seizure. The spike wave is simulated by step changes in the bifurcation parameter, which is proportion to the concentration of the intracellular calcium ions (|Ca|1 ). And, when the concentration of (|Ca|1  is sufficiently large, the multi-spike wave can also be reconstructed. The simulation work will be helpful to understand how the EEG morphology is formed from the microcosmic viewpoint


We re-examine the recent suggestion of a high fraction of transition discs (i.e. those with a cleared inner hole) in M stars, motivated by the fact that we expect that, for M stars, even discs without inner holes should exhibit very weak excess shortwards of around 10 μm. Our analysis of spectral energy distribution models suggests that this indeed means that M stars where a detectable excess begins at around 6 μm may be misclassified as transition discs when in fact they have optically thick dust extending in to the dust sublimation radius. Consequently, we estimate that the transition disc fraction among M stars in the Coronet cluster is ∼15 ± 10 per cent (rather than the recently claimed value of 50 per cent). This revised figure would imply that the transition disc fraction is not after all markedly higher in later type stars. We suggest that, for M stars, transition discs can only be readily identified if they have emission that is close to photospheric out to >10 μm.


The formation of professionally oriented qualified medical personnel is a priority task of medical education. The incomplete understanding of students about their future specialty, the lack of knowledge about popular medical areas do not always allow them to make an informed choice. As a solution to the above problems, career guidance simulation trainings are of interest.


Software patents and business method patents have been 'available' in Australia for years. They are generally patentable in Australia, subject to restrictions that may be described as similar to those imposed in the U.S. Since the 2001 Australian decision in Catuity, for example, it has been inextricably clear that certain forms of automated business methods may be patented in Australia. However, a number of recent decisions of the Australian Courts (which have been followed by the Patents Office) demonstrate that merely computerizing established business methods and software will not result in a valid patent. This article will outline the current state of the law concerning determining the patentability of certain computer-implemented inventions and methods in Australia, and lessons that can be learnt from recent cases in the United States.


Chloroplast protease AtDeg2 (an ATP-independent serine endopeptidase) is cytosolically synthesized as a precursor, which is imported into the chloroplast stroma and deprived of its transit peptide. Then the mature protein undergoes routing to its functional location at the stromal side of thylakoid membrane. In its linear structure AtDeg2 molecule contains the protease domain with catalytic triad (HDS) and two PDZ domains (PDZ1 and PDZ2). In vivo AtDeg2 most probably exists as a supposedly inactive haxamer, which may change its oligomeric stage to form active 12-mer, or 24-mer. AtDeg2 has recently been demonstrated to exhibit dual protease/chaperone function. This review is focused on the current awareness with regard to AtDeg2 structure and functional significance.


Background—Mechanoelectrical feedback caused by atrial dilatation plays an important role in atrial fibrillation (AF). To test the hypothesis that remodeling is reversible by reducing atrial stretch, we investigated electrophysiological changes after a reduction of left atrial (LA) pressure in patients undergoing percutaneous balloon mitral commissurotomy (PBMC). Methods and Results—In 22 patients with chronic AF who were undergoing PBMC for mitral stenosis, internal cardioversion was successful in 19 patients (86%). Twelve patients with sinus rhythm acted as controls. Mean LA pressure was significantly reduced after PBMC (18.5±5.9 mm Hg versus 10.2±4.1 mm Hg;P <0.001). The effective refractory period (ERP), conduction delay (CD), and the index of heterogeneity (CoV) of the ERP and CD were compared. Changes in LA pressure were only significantly correlated with AF vulnerability (r =0.7;P =0.02) and CoV of CD (r =0.3;P =0.03). There were no significant changes in ERP and CD immediately after PBMC in the AF group. However, the overall CoV of ERP was reduced in the AF group after PBMC. There were homogenous, although not significant, increases in regional ERP in the control group immediately after PBMC. Atrial CD and CoV of CD were significantly reduced after PBMC in the control group; this was most prominent within the regions of the LA. Conclusions—AF vulnerability and CoV of CD correlated significantly with LA pressure. A homogenous increase in regional ERPs could be demonstrated in the control group after an immediate reduction of atrial stretch, whereas the recovery course of electrical remodeling was prolonged and heterogenous in the AF group. Regional conductions were irreversible in patients with preexisting AF.


Objective: Study to application of hard ureteroscope and civil holmium laser in management of ureteral calculus.Methods: Data 18 patients who underwent ureteroscopic intracorporeal lithotripsy by the holmium laser in our hospital were analysed retrospectively.Dolichodiameter of ureteral calculus are 0.8-1.3cm.14 patients have nephrohydrosis and 6 patients have acute nephric colic and 7 patients have polyp of ureter in the same side simultaneously.Results: Only once operation cure ureteral calculus in all patients.Mean operative time is 24min and no postoperative complications happen.Ureteral stent is indwelled 6-8weeks in each patient and length of stay of patients are 5-7days after operation.Follow-up visit is that all patients are cured.Conclusion: Lithotripsy of hard ureteroscope and civil holmium laser is a kind of safety and effective method of management of ureteral calculus.


The first CVD nanocrystalline diamond micromechanical disk resonator with material-mismatched stem has been demonstrated at a record frequency of 1.51 GHz with an impressive Q of 11,555, which is more than 7X higher than demonstrated in a previous 1.14-GHz polysilicon disk resonator, and which achieves a frequency-Q product of 1.74/spl times/10/sup 13/ that now exceeds the 1/spl times/10/sup 13/ of some of the best quartz crystals. In addition, a 1.27-GHz version with a Q in the excess of 12,000 exhibits a measured motional resistance of only 100 k/spl Omega/ with a dc-bias voltage of 20 V, which is more than 34X lower than measured on a pure polysilicon counterpart at 1.14 GHz. At 498 MHz, Q's up to 55,300 in vacuum and 35,550 in air have been demonstrated, both of which set frequency-Q product records at 2.75/spl times/10/sup 13/ (vacuum) and 1.77/spl times/10/sup 13/ (air).


In April, 2012, Hsien-yung Pai published a photography-based book "Father and the Republic: Impressions of General Pai Chung-hsi" simultaneously in Taiwan, Hong Kong and China. Pai stated that he spent more than a decade on historical research in order to write this work, which is both a biography of his father and a new look at Republican history. The book features hundreds of images, and the accompanying text gives a detailed account of the relationship between General Pai and the Republic of China. However, this book was simply a prelude for the follow-up publication of "The Biography of Pai Chung-hsi".Both books come in two volumes to present the life of Pai Chung-hsi, with each volume containing approximately the same number of pages. The first volume covers his military life on the Chinese mainland, and the second volume documents his 17 years in Taiwan. General Pai distinguished himself as a brilliant military commander of the forces for several decades in China, but then led a melancholy and lonely life in Taiwan. The author establishes historical connections between the second half of each biography and the issue of Republican history in Taiwan, and it is this issue that is examined in this paper.More specifically, this study focuses on the relationship between General Pai and the February 28 Incident, the couplets that he wrote after this event and later was inscribed at Tainan Koxinga Shrine, and the actual historical facts underlying the narrative presented in the two biographies.


The current ecological, economic and social crisis calls for a change in the paradigm of new product development. Considering the social responsibilities of designers, Design Studio FEUP is developing a research project within the master program of Product and Industrial (MDIP), entitled We Won't Waste You (WWWY) in which students are challenged to develop products by using discarded materials in different contexts. One of the initiatives, in partnership with the City Council of Matosinhos, is OFICINA DESIGN which comprises two phases. The first phase is the development of an active teaching method where students can get in touch with sustainable requirements by designing products from discarded materials, while the second phase is the interaction between designers and vulnerable groups that will manufacture the products. This paper aims to present an overview of the projects and their role on the creation of a new design approach for the MDIP students. The project Pérolas de Matosinhos is described in detail.


Cyanobacteria (green-blue algae) can release hazardous secondary metabolites, called cyanotoxins, with a variety of chemical structures and modes of toxicity. Among them, saxitoxins are neurotoxins, mostly known for causing food poisoning when eating shellfish seafood. Saxitoxin analysis from shellfish has been thoroughly investigated. However, analysis of saxitoxins from spirulina supplements, derived from blue-green algae, is understudied, despite the fact that spirulina is used as part of the human diet and could lead to an increased risk for the consumer due to contamination from cyanotoxins. In this study, an analytical method has been developed using Liquid Chromatography tandem Mass Spectrometry (LCMS/MS) for the analysis of saxitoxins from spirulina supplements and cyanobacterial mass. Target saxitoxins were Saxitoxin, decarbamoylsaxitoxin, Neosaxitoxin, Gonyautoxin 2&3, decarbamoylgonyautoxin 2&3. Separation was achieved using a HILIC chromatographic column with a gradient elution program of acetonitrile and water, both containing ammonium formate 2mM and formic acid 3.6mM. Identification was achieved using MS/MS in positive ESI mode. Extraction of saxitoxins was achieved with acetic acid in acetonitrile/water 50:50 with recoveries 30-40% due to matrix suppression. Solid Phase Extraction (SPE) with different cartridges (C18, Carbon Graphitized) did not improve the obtained recoveries. Nevertheless, column clogging was decreased, as column pressure remained in a steady value. Limits of detection (LODs) were 0.14-0.23μg g -1 (dry weight) and mean relative standard deviation (%RSD) was 15-20%.


Press and the Post A G Noorani A LITTLE -NOTICED news report by the UNI under a New Delhi, February 14 dateline reveals in a flash how dependent the freedom of the press is on the vagaries of the postal services. The report is set out in extensor Parliament Street Post Office here today refused to send the PUCL Bulletin, a journal of the People's Union for Civil Liberties, to destinations in Assam for 'unknown reasons', Delhi PUCL General Secretary Inder Mohan claimed.


The analysis of the diurnal variations in the large mesospheric electric fields obtained over different world regions with a new technique for remotely sensing the parameters of the electrically active mesosphere is presented. These variations are shown to have two maxima. A comparison of the results obtained with the Carnegie curve shows common features in the temporal behavior of the mesospheric electric field and the fair weather electric field at ground level.


Aim: The long-term detection of synthetic glucocorticoids was requested in urine and hair samples, due to the suspicion of hidden applications in patients suffering from allergies. Methods: Urine was extracted with TBME following enzymatic hydrolysis. Hair samples were segmented, washed, snipped, and extracted with methanol. The hair extract was purified by SPE (Plexa, Agilent). The detection of 18 glucocorticoids in urine and 17 glucocorticoids in hair was realized by LC-MS/MS using a C18 column (Hypersil Gold, 50 x 2.1 mm, 3μm, Thermo Scientific) and a Sciex QTrap 5500 instrument. Results: Triamcinolone acetonide was confirmed in urine (concentrations ranging from LOD 0.4 ng/ml up to 25 ng/ml) as well as in hair samples (concentrations between LOD 0.1 pg/mg and 57 pg/mg). Discussion: The uptake of the synthetic glucocorticoid triamcinolone acetonide was proven for the last weeks/months before sample collection (up to one year in case of one hair sample). However, the route of application could not be differentiated. Conclusion: The analytical results in urine and hair substantiate the initial suspicion of a deceptive application of triamcinolone acetonide during pretended traditional acupuncture treatments.


Abstract Agitation has always been recognised as a necessary parameter for electrodeposition. However since its inception in 1840, the purpose has changed from avoiding stagnation to increasing production rates and quality properties of the deposit. Consequently, the mode of agitation has changed substantially. In the present paper, the methods and purposes of agitation are discussed and related to the enhanced characteristics achieved and the disadvantages which may arise.


Devlonics Control NV has developed, in co-operation with the Belgian Government and Leuven University, an advanced technology road traffic detection, measurement and control system, known as CCATS. CCATS uses video camera sensors coupled to electronic units that undertake image signal processing in numeric mode. CCATS units are now going into operational service in Europe. The system provides complete and accurate data on road traffic conditions and automatic traffic control. Particularly significant in CCATS development has been the software means to differentiate between wanted data from video images of moving vehicles and unwanted information from moving shadows, reflections, rain, hail, snow etc.


Objective To investigate the expression changes of endoplasmic reticulum protein 29 (ERp29) in the rat brain tissue after cerebral hemorrhage, and explore its role in cerebral injury secondary to intracerebral hemorrhage.Methods Sixty SD rats, weighting (200±20) g, were randomly divided into normal control group (n=10) and cerebral hemorrhage group (n=50); rat models in the cerebral hemorrhage group were induced by stereotactic injection of autologous blood into the caudate nucleus. RT-PCR and Western blotting were employed to detect the mRNA and protein expressions of ERp29 and endoplasmic reticulum chaperones BIp/GRp78 at 6, 12, 18, 24 and 48 h after the inducement. Results The mRNA and protein expressions of BIp/GRp78 began to increase 12 h after the inducement, and gradually increased with the time prolongation, reaching their peak levels at 48h after the inducement, which were significantly different as compared with those in the normal control group (P≤0.05). The mRNA and protein expressions of ERp29 in the cerebral hemorrhage group at 6 and 12 h after the inducement showed no obvious changes as compared with those in the control group (P>0.05), while the mRNA and protein expressions of ERp29 in the cerebral hemorrhage group 18, 24 and 48 h after the inducement were obviously increased as compared with those in the control group (P≤0.05).Conclusion The endoplasmic reticulum stress response is activated in the surrounding brain tissue of hematoma and the expressions of ERp-29 is up-regulated at this process, which indicates that ERp-29might play a protective role and interact with Bip/GRp78 to inhibit the process of endoplasmic reticulum stress response so as to decrease the damaged effect of hematoma to the surrounding brain tissue.

Key words:
Cerebral hemorrhage; Endoplasmic reticulum protein 29; Bip/GRp78; Endoplasmie reticulum stress response


The use of the optical fiber have an exponential growth in all areas (telecommunications, automation, avionics. ... etc.). The International Telecommunication Union - sector of the Telecommunication Standardization (ITU-T) recommend several fiber types. In Algeria and most countries, the G652 fiber is the most used. Operators must act in accordance with the rules of the installation and connection of this fiber, if they want that the optical fiber cable retains the same characteristics. In this work, we investigate the characteristics of the optical fiber installed in Algeria, in order to evaluate it versus the ITU-T recommendations.


Seed coat fragments that remain in lint after the ginning process decrease spinning efficiency at the textile mill, and ultimately reduce the quality of finished goods. An experiment was conducted to determine the impact harvest and seed cotton cleaning treatments had on the fiber quality attributes of an upland cultivar known to have fragile seed coats. Three harvester treatments examined spindle size (diameter) and speed (rpm) on the picker: 13-mm (1/2-in) spindles operated at 2000 rpm; and 14-mm (9/16-in) spindles operated at either 1500 or 2400 rpm. Three seed cotton cleaning treatments varied the number of seed cotton cleaners from none to twice as many as customarily used. Seed coat nep count in the fiber as determined by AFIS was used as an indicator of seed coat fragment levels. Results showed that using a larger spindle diameter lowered seed cotton trash content at the wagon and feeder, produced less short fiber, and a higher color grade: however, seed coat nep count was not different. Increasing the number of seed cotton cleaners reduced trash content in the seed cotton (at the feeder), cottonseed, and fiber and improved color grade but not seed coat nep count. All other fiber and cottonseed properties were not different among harvesting or seed cotton cleaning treatments. It appeared that neither spindle size, spindle speed, nor increased seed cotton cleaning helped manage seed coat fragments. Future research is planned to examine possible methods to reduce seed coat fragments through modifications at the lint cleaner.


Adolescence is a time when individuals begin to explore and experiment with sex. Parents play an important role in directing and providing support to adolescents regarding sexuality so that adolescents do not fall into unwanted things. Integrated Behavior Model (IBM) theory is a theory that suppresses individual behavior change determined by intention. Intention cannot be formed without self-efficacy. The purpose of this study was to determine the effect of self-efficacy on parent-adolescent sexual communication behavior mediated by intention. This research uses a quantitative approach with a correlational research design. The subjects of this study were 315 parents who came from various cities in Indonesia and had teenage children aged 14-17 years. Analysis of the data in this study uses mediation analysis to measure that the intention to be a mediator of self-efficacy on sexual communication behavior. The results showed that self-efficacy had a direct effect on the estimate value -0.037  and indirectly or through the intention on parent-adolescent sexual communication behavior with an estimate value 0.013. It is also hoped that parents can increase the desire to engage in sexual communication with their teenagers.
Keywords: Intentions, self-efficacy, sexual communication, sexual communication behavior


Objective To observe the therapeutic effects of integration of traditional Chinese and Western medicine on congestive heart failure .Methods Seventy three patients suffering from congestive heart failure, were randomly divided into two groups: in treated group (n=47) Tongxinluo A 3 Capsule was orally taken at 4 pills once three times a day and Ciwujia Injection of 40 60 ml was intravenously infused once a day; in control group(n=26) the Western routine therapy was taken, with the therapeutic courseof 10 15 d. Results The overall effective rate was sifnificantly higher in treated group(87.2%) than that in control group(65.4%) (P0.05).Conclusions The integration of traditional Chinese and Western medicine mentioned above is effective for the congestive heart failure.


We describe two cases illustrating the use of bedside ultrasonography in the trauma room, to confirm femoral fracture, and to guide accurate placement of femoral nerve block.

A 13 year old boy was brought to the emergency department (ED) by ambulance. He was undergoing leg lengthening surgery and had an external fixation device attached to his left femur. He had fallen onto his left knee at school, with subsequent pain and inability to bear weight. There was a tender swelling over the lateral supracondylar area of his left femur, with severe pain on minimal movement. Bedside ultrasonography in the ED was used to confirm the …


Given the current threat posed by toxic digital content, preparing students to evaluate online sources cannot be relegated to a single subject area—this instruction should happen across the curriculum. This article focuses on materials designed to teach students to evaluate online information across subject areas. ninth-grade biology and world geography teachers taught a series of curriculum-embedded lessons based on the following design principles: (a) Focus on a core question and strategy; (b) engage students in evaluating real online content; (c) feature cognitive apprenticeship and formative assessment; and (d) support teacher learning. We examine whether these lessons helped students become more skilled evaluators of online content. Pretest/posttest data (N =574) showed statistically significant growth in students' ability to evaluate the credibility of online content. We analyze the role played by the curriculum design principles in this interdisciplinary intervention and explore implications for future initiatives.


Two questionnaires (Students Evaluation of Education Quality, SEEQ and Self-esteem Scale, SES) are used to explore the influence produced by the factors like the students' self-esteem, urban and rural status, and gender difference on the sports majors' evaluation when they evaluate the teaching effects of theory course teachers. The findings revealed: 1. The questionnaire SEEQ has a high reliability and validity when it is used in the teaching evaluation based on network. 2. In the evaluation, the interaction of the students' self-esteem and their gender reaches a significant level. The students with low self-esteem score the teachers low, and girls from the groups with high and middle self-esteem have a higher evaluation of the teachers than boys. 3. The scores of the students from rural areas are significantly higher than those who come from cities.


This study investigated the effect of more than two consecutive NPs bearing the nominative case-marker -ga on the processing difficulty associated with Japanese multiply center-embedded sentences. Experiment 1 found that NP-ga sequences are rated substantially less favorably for processability ratings than their matched counterparts; thus, theories that predict processing load must offer an account of this special source of processing difficulty. Experiment 2 used an alternation in Korean nominative particles -i and -ka, phonologically triggered, to narrow the sense in which it might be said that the cost of NP-ga sequences arises because of a problem in discriminating among consecutive NPs. In this case, processability ratings provided no evidence that confusable NP-Nom's are made more distinct by purely phonological variation in their case-markers.


Objective : To assess clinical and biological correlation of systemic manifestations of primary Sjogren's syndrome (SS). The diagnosis of our patients used the preliminary european criteria established in 1993. Material and methods: It's a retrospective study about thirty tree patients with primary SS are documented (32 women and 1 men; men age: 45, 3 years). Results : The systemic manifestations are present in 91% and they were reasons for hospital referral in 42% of cases. They included 85% of particular signs, 21% of muscular manifestations and 24% of Raynaud phenomenon. Pulmonary involvements found in 45% cases, neurological manifestations in 15% and renal disorder in 30% cases. Antinuclear antibodies were found in 52% and rheumatoid factor in 60%. Conclusion : Systemic manifestations are frequent in our series. There incidence are similar with the literature, except for the neurological involvement with is rare.


Disclosed is a Group III nitride semiconductor thin film of high quality and for which it is used, a group III nitride semiconductor light-emitting device. To obtain the Group III nitride semiconductor thin film, a AllnN buffer layer -Plane on a (1-102) (so-called r-plane) sapphire substrate is formed using a MOCVD apparatus at atmospheric pressure, wherein the temperature of the substrate in a range of 850 to 950 ° C is maintained and is then allowed to, a GaN-based compound such as GaN, AlGaN or the like at a high temperature grown epitaxially on the buffer layer. The group III nitride semiconductor light-emitting device is fabricated using the group III nitride semiconductor thin film as the base layer.


There is high persistence rate of cervical intaepithelial neoplasia(CIN)in pregnancy.This paper reviews methods screening for CIN in pregnancy,and concludes that conservative management by repeated colposcopy and colposcopically directed biopsies is a safe and reliable method.Colposcopy excluding microinvasive or invasive carcinoma allow the gynecologist to defer definitive therapy to the postpartum period,when the fetal and maternal risks are obviously diminished.The addition of the acetic acid test(AAT)will overdiagnose to some extent,but the sensitivity will be significantly improved.Loop electrosurgical excision and cone biopsy of the cervix during pregnancy should be reserved for patients with evidence or suspicion of carcinoma by biopsy or colposcopy.CIN during pregnancy have a high progression,but we should ensure a high follow up.


We derive models and relations which might be useful for the calibration and orbit determination of cartwheel configurations such as proposed by Massonnet (2001). The aim is to develop a method to obtain precise position and velocity estimates for each individual cartwheel satellite from noisy and erroneous measurements (e.g. GPS). For later interferometric SAR processing precise estimates of the baseline vectors between the satellites are essential, because every error in the position of the antenna leads to a multiple error in height of the digital elevation model. The whole approach is based on state space arguments giving rise to Kalman filtering methods.


Abstract The focus of this study is on the interrelations between ageing societies and capital markets. In this context, a number of interesting questions arise, which this study discusses: What is the future role of capital markets for old-age provisions? Which investment alternatives will gain importance? How will savings in general be affected? What is the impact on securities prices? How likely is a so-called asset meltdown ( i.e. a rapid fall in securities prices due to a withdrawal of assets by the retiring baby-boomer generation)? Can international diversification help to mitigate such negative effects? Our study is based on a survey among financial experts. Their assessment of the effects of ageing societies on capital markets is presented and discussed.


Measurement results of the switching field of a thin film longitudinal media sample for times down to ~0.4 ns are only 5% larger than the Sharrock's Law extrapolation of data measured with field exposure times ranging between 8 ns and 270 hr. LLG based micromagnetic analysis verify that the lack of a large gyromagnetic enhancement of the switching field for subnanosecond pulses is due to exchange and magnetostatic interactions between the grains. This analysis was also used to verify that the use of a DC pedestal field that is half of the total field does not significantly alter the results


The existence of a principal subalgebra of type slq(2) for quantum enveloping algebras glq(l+1) or slq(l+1) is investigated. Surprisingly, only when l=2 and when all relations are restricted to symmetric representations such a principal subalgebra happens to exist. This case, slq(3)slq(2), is the q-deformation of the classical su(3)so(3) embedding for symmetric su(3) representations, and is analysed in more detail, giving a connection with q-deformed spherical harmonics.


Abstract.
 The occurrence and nesting phenology of Ardeidae species and other wading birds were documented from 2009–2013 in the Bahía Kino bioregion of western Sonora, México. Two active colonies were surveyed: in a mangrove (Avicennia germinans; Rhizophora mangle) estuary and on a nearshore desert island. Thirteen species of nesting wading birds were recorded, 11 of which are year-round residents and two occurring only during the breeding season; two additional species were documented only in migration. The most abundant species was the Snowy Egret (Egretta thula), which had a peak of 234 nests in 2012. Of particular conservation interest is the Reddish Egret (E. rufescens), which had a peak of 149 nests in 2012. Potential prey of wading birds in the estuary was also sampled, with special focus on brachyuran crabs, which constitute the main prey items of the Yellow-crowned Night-Heron (Nyctanassa violacea). The rapid development of the region, and especially the establishment of largescale mariculture operations along Estero Santa Cruz, has the potential to impact local wading bird populations, and thus an understanding of wading bird diversity, abundance and habitat use may prove critical to inform future management and conservation initiatives.


Simple Summary [68Ga]Ga-DOTA-SSTR PET imaging has recently been introduced in the management of patients with brain tumors, mostly meningiomas and pituitary adenomas or carcinomas. The current literature demonstrated the superior diagnostic accuracy of this imaging modality, especially for lesions difficult to be detected or characterized on conventional imaging protocols, such as skull base or transosseous meningiomas. [68Ga]Ga-DOTA-SSTR PET tracers also seem to provide superior volume contouring for radiotherapy planning and may also be used to evaluate the tumor's overexpression of somatostatin receptors for devising patient-tailored peptide receptor radionuclide therapy. In this review, we comprehensively analyzed the current literature discussing the implementation of [68Ga]Ga-DOTA-SSTR PET imaging in brain tumors, further presenting ongoing clinical trials and suggesting potential future applications. Abstract Background: The development of [68Ga]Ga-DOTA-SSTR PET tracers has garnered interest in neuro-oncology, to increase accuracy in diagnostic, radiation planning, and neurotheranostics protocols. We systematically reviewed the literature on the current uses of [68Ga]Ga-DOTA-SSTR PET in brain tumors. Methods: PubMed, Scopus, Web of Science, and Cochrane were searched in accordance with the PRISMA guidelines to include published studies and ongoing trials utilizing [68Ga]Ga-DOTA-SSTR PET in patients with brain tumors. Results: We included 63 published studies comprising 1030 patients with 1277 lesions, and 4 ongoing trials. [68Ga]Ga-DOTA-SSTR PET was mostly used for diagnostic purposes (62.5%), followed by treatment planning (32.7%), and neurotheranostics (4.8%). Most lesions were meningiomas (93.6%), followed by pituitary adenomas (2.8%), and the DOTATOC tracer (53.2%) was used more frequently than DOTATATE (39.1%) and DOTANOC (5.7%), except for diagnostic purposes (DOTATATE 51.1%). [68Ga]Ga-DOTA-SSTR PET studies were mostly required to confirm the diagnosis of meningiomas (owing to their high SSTR2 expression and tracer uptake) or evaluate their extent of bone invasion, and improve volume contouring for better radiotherapy planning. Some studies reported the uncommon occurrence of SSTR2-positive brain pathology challenging the diagnostic accuracy of [68Ga]Ga-DOTA-SSTR PET for meningiomas. Pre-treatment assessment of tracer uptake rates has been used to confirm patient eligibility (high somatostatin receptor-2 expression) for peptide receptor radionuclide therapy (PRRT) (i.e., neurotheranostics) for recurrent meningiomas and pituitary carcinomas. Conclusion: [68Ga]Ga-DOTA-SSTR PET studies may revolutionize the routine neuro-oncology practice, especially in meningiomas, by improving diagnostic accuracy, delineation of radiotherapy targets, and patient eligibility for radionuclide therapies.


Objective To analyze the CT appearances and characteristics of various breast lesions. To evaluate the CT value variation after enhancement(ΔCT) in relation to the nature and size of lesions and the possibility of nodal staging by CT. Methods Between July 1996 and April 2000,81 breast tumor patients (with 93 lesions )examined by CT were retrospectively analyzed. All these cases were diagnosed histopathologically. Among them, 35 cases (with 36 lesions) were malignant and 43 cases (with 57 lesions) were benign. Results The average CT values of benign and malignant groups on pre consrast scan were 21.24±7.24 HU and 25.65±9.43 HU respectively ( P 0.05). The average ΔCT of two groups were 16.86±17.77 HU and 35.36±15.07 HU respectively on contrast enhanced scan ( P 0.01). The tumors with spicules or segments in benign and malignant groups were 63.89% (23/36) and 15.79% (9/57) respectively ( P 0.01). In case the lesion was less than 1 cm. In size, ΔCT was less than 30 HU in all non calcium benign lesions and was larger than 30 HU in 40% malignant tumors 53.3% (8/15) lymph node metastasis could be detected by CT, among them the lymph nodes of stage N 2 were 85.71%(6/7).Conclusion Breast CT examination is an effective method and can give useful informations in the differencial diagnosis and TNM staging for patients with breast tumors.$$$$


Automated voice anonymization algorithms are used to obfus-cate speaker identity while leaving other vocal attributes un-touched; they have been used for e.g., speech recognition, speech emotion detection, and most recently, remote speech-based health diagnostics. However, speech data is commonly collected in an uncontrolled manner in various environments, potentially compromising its quality, and frequently omits key metadata that could improve model performance. In this study, we employed the Cambridge COVID-19 sound database and used COVID-19 detection as a case study. We first present descriptive statistics on sample composition (i.e., COVID-19 status, age, gender). We also present a measure of signal-to-noise ratio (SNR), a feature of speech that can denote individuals' socioeconomic status. Next, we assess how age and SNR, the two most unbalanced features of the dataset, are associated with model performance and the impact of automated anonymization algorithms performance. Our findings suggest the existence of diagnostic biases related to age and SNR of the recording, which become more prominent after anonymization. To tackle these biases, we explore the usefulness of two data augmentation methods. We show that although data augmentation helps to recover some loss in overall performance, it can lead to a larger discrepancy in performance for over-represented and under-represented groups. We conclude with a discussion of the limitations associated with using SNR as an indicator of socioeconomic status, and of the potential effects of diagnostic biases associated with socioeconomic status.


ABSTRACT Competitive foam separation of two rare earth elements (REEs), Eu(III) and Tb(III), are investigated in this study in presence of ethylenediaminetetraacetic acid (edta) using cetylpyridinium chloride (CPC). The effects of pH, [edta]/Σ[REEs] and [CPC]/[edta] molar ratio, frother concentration, ionic strength and air-flow rate on the foam separation efficiency are also evaluated. At the optimal experimental condition, Eu(III)/Tb(III) separation factor of 141.56 is obtained. The kinetic data obtained at all the studied parameters are analyzed by the flotation first-order and second-order kinetic models. Eventually, a schematic flow-sheet for Eu(III)/Tb(III) separation is proposed.


In this experiment, we explored the role of astragaloside in regulating Egr-1 through S14G-humanin on asthmatic airway inflammation. 64 juvenile Sprague Dawley (SD) rats were selected. After establishing rat asthma model, they were assigned into blank control group, astragaloside group,
 S14G-Humanin group and astragaloside+S14G-Humanin group (combined group). Astragaloside group was intervened with astragaloside II 0.6 mg/kg, S14G-Humanin group was intervened with 50 μm S14G-Humanin, combined group RBSMCs were treated with astragaloside II 0.6 mg/kg and 50 μM
 S14G-Humaninn. Airway responsiveness was assessed and pathological damage of lung tissue was assessed by HE staining along with analysis of inflammatory cells in bronchoalveolar lavage fluid (BALF), inflammatory cytokines and bone-marrow derived mesenchymal stem cells (rBMSCs) behaviors. Compared
 to blank control, the Penh values of astragaloside group, S14G-Humanin group and combination group were increased (P <0.05) and pathological scores were lower with the lowest score in combined group (all P <0.05). The number of white blood cells, neutrophils, eosinophils,
 macrophages and lymphocytes in BALF of rats in astragaloside group, S14G-Humanin group and combination group were decreased, with the lowest number in combination group (P <0.05). In addition, IL-4, IL-6, and IL-21 in astragaloside group, S14G-Humanin group and combination group
 were reduced, with the lowest levels in combination group (P <0.05). RBSMCs proliferation and migration ability in treatment group was reduced with the lowest in combination group (P <0.05). After up-regulating S14G-Humanin, Egr-1 mRNA expression was elevated (P
 <0.05). Astragaloside can reduce inflammatory cells and inflammatory cytokines and increase the expression of Egr-1 by regulating S14G-Humanin expression.


Several studies have shown that weight changes are common in patients with coeliac disease after starting a gluten‐free diet (GFD), but data on the prevalence of metabolic syndrome in this population are still scarce.


The article attempt to analyze the structure of fictional market in Argentina. For that, it is proposed to highlight the number of fictions produced and exhibited in the period 2002-2015, the main producers, the channels television and the modality of financing (public or private). This research is based on a communicational perspective, the Political Economy of Communication to understand the characteristics of the television industry and cultural goods. The methodological approach is based on the documentary and bibliographical survey so as to systematize the data for the research.


This paper explores the application of options in supply chain risk management when consumer demand is uncertain. The analysis is based on an environment involving a single supplier and multiple retailers. Each retailer can either buy product directly from the supplier, or purchase options on product. An option gives the retailer the right to buy an additional unit of product. We first derive optimal replenishment policies for the retailers, the optimal production policy for the supplier. We then show how options enhance information flows, encourage risk sharing, and improve supply chain efficiency. The paper includes a discussion of how options can be used to align the incentives of supply chain partners, and to improve supply chain responsiveness to changes in the business environment.


The invention proposes a device (1) for releasable attachment having a first sleeve (3) and a second sleeve (2) intended to be inserted into the first sleeve (3), and an elastic member (12) adapted to axially lock the two sleeves relative to one another and radially retractable during insertion of the second sleeve (2) in the first sleeve (3). One of the sleeves (3) comprises an actuator (19) movable axially relative to the sleeve (3) between a first axial locking position of the two sleeves (2,3) by the spring element (12), and a second position unlocking sockets by radial retraction of the elastic element (12).


Promote Students' Understanding of Engineering Dynamics: A True/False Reasoning Practice Dr. Shaobo Huang, South Dakota School of Mines and Technology Dr. Shaobo Huang is an Assistant Professor and the Stensaas Endowed STEM Chair in the Department of Mechanical Engineering at South Dakota School of Mines & Technology. Her research interests include student retention and academic performance in engineering, student achievement evaluation and assessment, and K-12 STEM curriculum design. Dr. John M. Mativo, University of Georgia Dr. John Mativo is Associate Professor at the University of Georgia


new hot strip mill is commissioned recently at Taiyuan Iron and Steel Company. The design of electrical control system for its large slab reheating furnace is accomplished by CERIS successfully. In this paper, a brief introduction about its drive system, basic automation system and system commissioning is presented.


Lower limb DVT is a common clinical entity and a clear history of DVT is found in about 20% of patients with CVU. In addition, an unknown and probably unquantifiable number of people develop asymptomatic DVT without ever knowing it. The presence of thrombus within a vein, especially where it is occlusive, leads to an inflammatory, possibly Ischaemic phlebitis. This is thought to be due to obstruction of the vena venorum and direct humoral and/or cellular damage to the endothelium. Patients presenting to hospital medical college and research institute with varicose vein to undergo surgery for varicose vein. Each patient with a typical history of symptomatic varicosis will be subjected to physical examination and preliminary investigations. Pain at 24 hours measured by visual analog scale (0: No distress, 10: Agonizing) is significantly more associated with conventional with P


This study aims at understanding the inventory system in consumer durable sector. A large dataconsisting of the sales, year, and price in several dimensions have been taken for the study. The studywould fetch the results of how the consumer durable industries in India deal with post manufacturinginventory system and its effectiveness. The secondary data collected and analysed from 1955 to 2016. Theinventory and sales levels are analysed and the factors like low user price and net user price areinferentially tested for association. Forecasting and trend lines are used for analyzing the inventorymovement further. Forecasting models and trend models are adopted to predict the inventory level in thesector. Cluster analysis has been used to understand the different groups and similarities of sub groups.Several models for inventory forecasting and adopting cluster analysis to identify various similaritypattern among the factors. It has made a significant outcome which can be utilized for further research.The major conclusion from the study is that there is a visible difference among the usage of inventorysystem among FMCG players with the timeframe differences.


(1969). Symbol and Allegory: A Problem in Literary Theory. The Germanic Review: Literature, Culture, Theory: Vol. 44, No. 4, pp. 273-288.


This parer introduced the measure on how to decide the 92417 type bearing detection threshold and provided judgement criterion for the detection of the bearing of the driving motor.


ABSTRACT This case study draws a specific link to the practice of action learning (AL) in China. We organized ourselves into an AL set and used Revans' AL, as interpreted by Marquardt (2004), to create a post-teaching dialog to examine the experience gained from delivering an interdisciplinary course online—a novice situation—in a Chinese transnational university. AL's questioning insight occurred after conducting an evidence-based evaluation of online teaching in an interdisciplinary higher education course that used Debattista's (2018) online teaching effectiveness rubric. The rubric offered rich 'programed knowledge' that triggered our question-based inquiry. We conclude that our AL approach is valuable for teacher professional development and offers our rationale for why this particular AL practice would be suitable for the Confucian culture, teaching of interdisciplinary courses, and in novice situations. By conducting AL, we identified a list of key findings, such as proactive communication among teachers in an interdisciplinary course, was vital when teaching to a large group of students. We offer recommendations to improve interdisciplinary online course design and delivery in the future based on reflections from the AL. Implications, limitations, and suggestions for future research are presented at the end of this paper.


This paper proposed the new current feed-back amplifier for low supply voltage application. The input stage was designed to be a class-AB circuit and achieve the low supply-voltage operation down to 2VTH+2VDS(SAT). With the self-adjust bias current, the high performance can be adopted with high stability. The circuit was successfully proven by the simulation with MOSIS 0.5 m µ MOS technology.


We seek to identify a policy rule for the Fed that remains valid in both periods of high and low financial stress. Using real‐time data, we examine traditional linear Taylor rules, Taylor rules augmented with a financial stress measure, and nonlinear Taylor rules for the Fed's response in the pre‐crisis period that lasts from 1982 to 2007. We determine that financial conditions were a significant source of nonlinearity in the Fed's response during this period, with greater volatility in the financial sector causing the Fed to prioritize the stabilisation of financial markets over its traditional policy objectives. We then extend the analysis to include the financial crisis of 2008 and find that our nonlinear Taylor rule framework also provides a plausible explanation for the Fed's conduct of monetary policy over this period. Our results, thus, show that the Fed's reaction to the recent financial crisis was not that dissimilar from its response to previous episodes of financial stress.


Phytochemical investigation of Trigonotis peduncularis resulted in the isolation of three aryldihydronaphthalene-type lignan sucrose diesters named trigonotins A-C (1-3). These lignans showed a strong yellow-green fluorescence emission under basic conditions. The structures of the new compounds were elucidated by means of spectroscopic methods, and the nature of their fluorescence was examined.


Raman and Brillouin lasers based on a high-quality (high-Q) whispering gallery mode microresonator (WGMR) are usually achieved by employing a tunable single-frequency laser as a pump source. Here, we experimentally demonstrate visible Raman and Brillouin lasers using a compact microresonator/ZrF4−BaF2−LaF3−AlF3−NaF (ZBLAN)-fiber hybrid system by incorporating a WGMR with a fiber-compatible distributed Bragg reflector/fiber Bragg grating to form a Fabry–Perot (F-P) fiber cavity and using a piece of Pr:ZBLAN fiber as gain medium. The high-Q silica-microsphere not only offers a Rayleigh-scattering-induced backreflection to form the ∼635  nm red laser oscillation in the F-P fiber cavity, but also provides a nonlinear gain in the WGMR itself to generate either stimulated Raman scattering or stimulated Brillouin scattering. Up to six-order cascaded Raman lasers at 0.65 μm, 0.67 μm, 0.69 μm, 0.71 μm, 0.73 μm, and 0.76 μm are achieved, respectively. Moreover, a Brillouin laser at 635.54 nm is clearly observed. This is, to the best of our knowledge, the first demonstration of visible microresonator-based lasers created by combining a Pr:ZBLAN fiber. This structure can effectively extend the laser wavelength in the WGMR to the visible waveband and may find potential applications in underwater communication, biomedical diagnosis, microwave generation, and spectroscopy.


Large-scale atmospheric circulation is a critical factor that controls the surface climatic conditions of a specific region. The scope of this work is to examine this relationship for different climatic regions over Greece and provide a detailed descriptive statistical analysis for multiple parameters related to heat and drought. The atmospheric circulation patterns are provided using a neural network approach and the surface climatic parameters are extracted from 17 surface meteorological stations for a 30-year period. In detail, for each circulation pattern the maximum and minimum temperature, the diurnal temperature range along with the precipitation amount are assessed. The 32 identified regimes describe effectively the large-scale atmospheric circulation and they are found to affect significantly the climatic parameters variability. Interesting statistical aspects are extracted for each climatic region and specific atmospheric circulation patterns are found to be associated with extreme heat and drought in the region. The persistence of atmospheric circulation is examined and associated with unusual episodes. The quantification of the large-scale effect on climatic parameters anomalies is demonstrated and is also discussed in terms of the effect of local topography and urbanization in each site.


LncRNA HOTAIR has different expression levels in different stages of tumorigenesis and development. Therefore, it has potential application in clinical diagnosing tumor stage as a tumor marker. Fifty patients with lung cancer and fifty healthy volunteers were selected as lung cancer group and control group respectively. According to T and N stage of cancer , the patients were divided into T1 、 T2 、 T3 and N0 、 N1 、 N2 groups. Fluorescence in situ hybridization (FISH) was used to detect the expression of HOTAIR in lung cancer tissues and paraneoplastic tissues. The expression levels of NSE, CEA and CYFRA21-1 in serum were detected by immunofluorescence. The results showed that the expression level of HOTAIR in paraneoplastic tissues (0. 98 ± 0. 04) were significantly lower than that in lung cancer tissues (3.56±0.15). The serum levels of NSE, CEA and CYFRA21-1 of the lung cancer group were higher than those in the control group. The concentrations of HOTAIR, NSE, CEA and CYFRA21-1 increased with the progress of clinical stages, which indicated that the expression of HOTAIR was positively correlated with the expression of SE, CEA and CYFRA21-1. These results indicate that HOTAIR, NSE, CEA and CYFRA21-1 are associated with the initiation and development of tumors. Therefore, HOTAIR combined with tumor marker can improve the accuracy of detection of pathological stage of lung cancer.


The aim of the study was to characterize the impact of the cytochrome P450 2B6 (CYP2B6), CYP3A4, CYP3A5 and ATP‐binding cassette sub‐family B member 1 (ABCB1) polymorphisms on nevirapine plasma concentrations.


A biosensor includes a working electrode 101, a counter electrode 102 opposing the working electrode 101, a working electrode terminal 103 and a working electrode reference terminal 10 connected to the working electrode 101 by wires, and a counter electrode terminal 104 connected to the counter electrode 102 by a wire. By employing a structure with at least three electrodes, it is possible to assay a target substance without being influenced by the line resistance on the working electrode side.


In India fast deterioration in milk quality has been observed in dairy value chain, which needs to be taken into consideration by introducing the concept of clean milk production. The present study was conducted in the area of Rajasthan Cooperative Dairy Federation (RCDF) to identify the socio-economic factors of dairy farmers, which affects the raw milk quality from pail to dock level. A total of 120 farmers were selected on the basis of proportionate random sampling from four district milk unions of RCDF. The milk samples collected from three different levels viz. pail (producer), Dairy Co-operative Society (DCS), and dock (processing plant) were analyzed using Methylene Blue Reduction Test (MBRT) to estimate milk quality. The raw milk quality in RCDF's dairy value chain was 'very good' at pail , 'good' at DCS and 'fair' at dock level. Data on different socio-economic factors of the respondents were analyzed using different statistical methods. The overall results revealed family education status, experience in dairying, social participation, land holding, herd size, annual income, and milk production and milk sale had positive and significant correlation with the milk quality at pail level of milk collection. These characters except land holding had positive and significant correlation with milk quality at DCS level. At dock level family size, social participation, land holding and milk sale had positive and significant correlation with milk quality; however, land holding had negative and significantly correlation. Social participation and annual income were able to explain 42.26 percent variability in the milk quality at pail level. At the DCS level social participation, land holding and milk sale were able to explain 54.09 percent of variability in milk quality. Family size, land holding, average milk consumption and sale were able to explain 28.15 percent variability in milk quality at dock level.


Pierre Robin sequence (PRS) is a malformation pattern characterized by the core triad of retrognathia, glossoptosis, and cleft palate that causes difficulty in glossopharyngeal–laryngeal–vagal functions. The etiology of PRS remains largely unknown; previous reports have suggested that it is caused by intrauterine constriction or external conditions such as oligohydramnios, breech position, or abnormal uterine anatomy. Genetic causes include occurrence as a manifestation of many single gene conditions and chromosomal rearrangements. Positional effect on some loci or genes, including SOX9 has also been posited as a cause. Here, we report on an 18‐month‐old girl born with isolated PRS. Clinical chromosome microarray analysis (CMA) revealed a maternally inherited ∼623 kb microdeletion that is −725 kb upstream of 5′ SOX9 at chromosome locus 17q24.3. Her mother had cleft palate. This region, although devoid of any genes, is known to have a position effect on SOX9 due to elimination of highly conserved non‐coding cis‐regulatory elements. This report supports the evidence that deregulation of an intact SOX9 coding region is a cause of or associated with isolated PRS, and provides further evidence that CMA in the clinical setting is a powerful tool in detecting microdeletions in gene "desert" regions that have pathogenic position effect on specific genes. © 2013 Wiley Periodicals, Inc.


A 1.4 GHz radiometer, ELBARA, was constructed in 2001 at the Institute of Applied Physics, University of Bern, in collaboration with and for studies at ETH in soil-moisture research, especially to infer soil-hydraulic properties from the dynamics of the water content in the top soil. ELBARA is used together with MORA, an older, but equivalent system at 11.4 GHz and with a set of time-domain reflectometer (TDR) sensors. In the normal setup, the radiometers are operated from a tower at incidence angles between nadir and zenith. Here we report on the realization and on features of ELBARA. Results from first measurements in 2002 were presented elsewhere.


The study of original literatures found that "Cephalotaxus fortuni Hook."(1850) has been confusedly cited as C.fortunei Hook.,C.fortunii Hook.,C.fortunei Hook.f.or C.fortuni Hook..However,according to Article 32.1,32.2,32.3,32.7,46.2,46.3,60.7,60.11,60C.1(a),60C.4 of International Code of Botanical Nomenclature(Vienna Code,2006),the specific epithet "fortuni" should be corrected as "fortunei",the author of the name C.fortunei should be ascripted to W.J.Hook.not to W.J.Hook.et J.Smith or Hook.f.(J.D.Hook.),and C.fortuni Hook.should be rightly cited as Cephalotaxus fortunei Hook.("fortuni").Also,on the basises of Art.32.1,31.1(b),34A.1,41.2,45.1,46.2,46.3 of Vienna Code(2006),the name of Cephalotaxus should be cited as "Cephalotaxus Sieb. Zucc.——Fl.Jap.Ⅱ.66.1870 " rather than "Cephalotaxus Sieb. Zucc.ex Endl.——Gen.Pl.Suppl.2:27.1842 ".


The traditional PID algorithm is improved by use of trapezoidal method and differential ahead algorithm,which enhances the stability and accuracy of the PID speed governing of DC motor.A method to measure DC motor's output torque by means of measuring armature current is presented based on the speed governing method of adjusting armature current and PWM principle.On the basis of LabVIEW and NI ELVISⅡ+ experimental platform,the speed governing system for DC motor has been built.The experimental results not only verify the validity of improved PID algorithm,but also the feasibility of the method to measure DC motor's output torque without torque sensor in CPM rehabilitation apparatus.


Intracerebral hemorrhage caused massive bleeding damaging surrounding brain tissue, enter and clog the ventricular system and cause increased intracranial pressure. Hypertension can increase the risk of intracerebral hemorrhage 3 -5 times. CT Scan is still a routine examination in patients with ICH because it can diagnose, measure the volume estimates and can determine the likely prognosis of the future looks like. The purpose of this study to analyze the correlation between the volume of bleeding with blood pressure in stroke patients with ICH. Conducted a retrospective observational analytic research with cross sectional study design (cross-sectional) is to determine the correlation between the volume of bleeding with blood pressure in patients with intracerebral hemorrhage stroke at Al Ihsan Hospital Bandung Neurology Department period January to December 2015. The data used is secondary data , taken from the patient medical record data, the population of the study all patients with intracerebral haemorrhage stroke who were treated at the Al Ihsan Hospital Neurology Department period from January toDecember 2015. A study of 48 patients who entered PIS inclusion and exclusion criteria. Correlation test results there is no significant relationship between the volume of bleeding with blood pressure level II both systolic pressure ( p = 0.988) and diastolic ( p = 0.182). There was no relationship between the volume of bleeding with blood pressure III degree either systolic pressure ( p = 0.862) and diastolic blood pressure ( p = 0.232). There is no correlation between the volume of bleeding with Systolic Pressure in Hypertension Isolated Systole ( p = 0.165). Correlation between the volume of bleeding with Diastolic Pressure in Hypertension Isolated Systole ( p = 0.044 ). Conclusion:There is no significant correlation between the blood pressure with bleeding volume in intracerebral hemorrhage patient


PURPOSE: To provide a single icon with which actions to be executed can be selected. CONSTITUTION: The icon is shaped like a dart board 10 or checkerboard 20. The dart board icon 10 represents 1st actions to be executed at radial positions of a cursor 38 positioned in this icon and 2nd actions to be executed in angular positions of the cursor. The checkerboard icon 20 represents 1st actions at horizontal positions of the cursor 38 positioned in the icon and 2nd actions at vertical positions. COPYRIGHT: (C)1993,JPO


The roles of school librarians as well as the needs of library users have been changing. To keep up with the changes, school librarians have been required to engage in professional development which enables them to acquire the necessary knowledge and skills for the effective provision of services and programs to their clients. School districts formulate policies that provide guidelines on the professional development requirements and activities for school librarians but there have been concerns on the effectiveness and approach of professional development as outlined in the policies. Using Ball's policy cycle theoretical framework, the study analyzed professional development policies within schools and interviewed school librarians to understand their perception of professional development. Findings from the study will enable librarians and administrators within the school and districts to understand the current state of professional development and may also suggest effective and innovative strategies in professional development for school librarians.


— Since fuel must be injected with appropriate pressure and time for accurate performance of diesel engines, then proper function of engine is influenced by accurate function of injector pump. At first total pump was designed by SolidWorks 2012 software. Then the total relationship of rotor, roller, internal cam ring, pole shoe and plunger in injector pump in MF285 tractor and their performance was shown. During suction state rollers connect with dents in internal cam ring and in pressure course pole shoes have drawer move in rotor and perform tappet action between rollers and plungers. The maximum stress was obtained by using analysis of finite element method. The maximum stress in contact surface of roller and internal cam ring and on roller surface. The maximum amount of this stress is 288.12 MPa. According to conducted analyses, the minimum value for safety factor is related to roller surface and it equals to 2.0477.


Automatic Type Curve Matching for Predicting Gas Wells Production Samson Tesfaslasie The determination of gas wells production using type curve matching is one of the methods used in evaluating gas reservoirs. Matching curves manually is time consuming and exposed to human error. Aminian type curves unlike the other type curves accounts the pressure dependency of gas properties and the effect of non-darcy factor. The sensitivity of Aminian type curves to non-darcy factor makes them hard to match with naked eyes. Sfrac is a computer program generates type curves using conventional calculations for wells where all the reservoir properties are available. Using the idea of Sfrac, a program was developed to generate type curves with non-darcy factor and initial gas in-place in addition to the gas properties. This computer program which is know as MatchCurve automatically matches the production history to generated type curves. Based on the automatic match production of gas wells is predicted.


Fénelon may be the most neglected of all the major philosophers of early modernity. His political masterwork was the most-read book in eighteenth-century France after the Bible, yet to now we have lacked a single interpretive monograph in English devoted specifically to his thought. This monograph aims to correct this by providing the first such book-length study. In focusing specifically on Fénelon's political thought, it has three primary aims. The first is to provide a reconstruction of Fénelon's political ideas accessible to those who might be encountering Fénelon directly or at length for the first time. The second is to demonstrate the connections between Fénelon's political thought and several other fields to which he made significant and long-recognized contributions, including not only philosophy and political science but also economics, education, literature, theology, and spirituality. Third, the book aims to cut several new edges in our extant understanding and appreciation of Fénelon's political thought and its significance. On this front, it specifically argues that Fénelon is better understood as a moderate and modern thinker rather than as a radical or reactionary, and that Fénelon deserves to be seen not merely as a political thinker but as a political philosopher. Finally, The Political Philosophy of Fénelon argues for Fénelon's relevance to our political world today. Fénelon was a nuanced and insightful diagnostician of ills from egocentrism and social atomism to authoritarianism and imperialism, and our understanding of these political phenomena so familiar to us today can benefit from attending to his insights.


A method of ICP-MS was proposed for the determination of trace amount of Mn,Cu,Zn,Cd,Ag and Pb in maceration extract of materials used for drinking water treatment.The material sample was macerated according to the method mentioned in National Standard GB/T 5750.Indium was used as internal standard. Detection limits were in range of 0.006-0.252μg·L~(-1).Values of recovery found were in the range of 85%- 107%.


A didactic experience developed in a physics course in engineering careers is described. The purpose was to incorporate activities in which language played a role in the reflection, debate and communication of the contents worked. The value of the arguments made by student's groups to questions about the movement of bodies is analyzed. The results demonstrate the need to revise the learning consignments and provide more guidance to students so that their arguments consider relevant evidence (justification), take into account the audience (persuasion) and consider opposing or alternative arguments (perspectivism).


The case-control design is a widely used approach for investigating associations between candidate genes and dichotomous disease traits. As mostcommonly implemented, cases are drawn from a population-baseddisease registry and unrelated controls from their source population, perhaps matching on age,


The purpose of this study was to analyze the influence of leadership, work stress, motivation, work environment and work performance at Airnav Indonesia Denpasar Branch. This study used simple random sampling technique on 68 respondents by taking respondents from permanent employees. The data used in this study were obtained from the measurement results of 68 employees (39 male employees and 29 female employees). The test was carried out by the PLS (Partial Least Square) method with the smartPLS program. The results of this study indicate that there is a significant influence of leadership on employee work performance. Job stress has a significant effect on employee work performance. Motivation has a significant effect on employee work performance. The work environment has a significant effect on employee work performance. Leadership has a significant effect on motivation. The work environment has a significant effect on the motivation of the employees of Airnav Indonesia Denpasar Branch.
Keywords: Leadership, Job Stress, Motivation, Work Environment and Performance


Surface modified SnS 2 nanoparticles are synthesized in mixed solvent of ethanol water by the reaction of SnCl 4, Na 2S and surface modification agent dialkyldithiophosphate(DDP). Infrared spectroscopy(IR), X ray photoelectron spectroscopy(XPS) and transmission electron microscopy(TEM) are used to investigate the structure, size, and morphology of the modified SnS 2 nanoparticles. The results show that the average diameter of the coated SnS 2 nanoparticles is about 7nm, and the dispersion capacity could be improved effectively by surface modification with DDP.


OBJECTIVE
To detect the active efflux gene qac gene in methicillin-resistant Staphylococcus aureus (MRSA) by hem-nested polymerase chain reaction (PCR) and to learn the carrier condition of qac gene.

METHODS
The active efflux gene qacA/B and qacB of 80 strains MRSA isolated from clinical specimens from Aug 2006 to March 2008 were amplified in vitro by hem-nested PCR with the primers designed by computers based on qac information of Genbank, and the PCR fragments were sequenced and analyzed.

RESULTS
We detected qacA/B in 19 out of the 80 MRSA strains (23.75%) and qacB in 18 out of the 80 MRSA strains (22.5%). Compared with sequences of qacA (NO.X56628) and qacB(NO.AF535087) in the Genbank, 98% and 97% were identical, respectively.

CONCLUSION
The active efflux gene qac gene in MRSA is detected by hem-nested PCR. The proportion of qac gene positive strains is high in clinical practice, which is related to its multi-antibiotic resistance.


out the human space flight program). In doing so, Burgess and Doolan pieced together what seemed like reasonable biographies of See and Bassett and then linked them to the larger story of the Moon landing program. Overall, Fallen Astronauts is a solid book, especially strong in describing each profiled individual's life story; if you want to know the contours of the life experiences of individual astronauts and cosmonauts, this book is certainly a useful resource. If you are seeking a broader discussion of the role and the place of the lives and deaths of astronauts and cosmonauts in society, however, Fallen Astronauts is not the book for you. Overwhelmingly, all of the astronauts and cosmonauts profiled here are portrayed as heroes principally because they died in the line of duty. Connecting death to heroism, though, is nothing new. For example, in 2002, social scientist Kathy Keltner analyzed 1,169 political cartoons that mentioned astronauts by name and found that while astronauts were depicted as heroes in 42 percent of the cartoons, those killed while performing their duties were overwhelmingly characterized as heroes. What does this mean for American society? How might an analysis of this theme illuminate the larger questions of human space flight and its place in society? We will need to wait for another scholar to explore these and other deep concerns in a study of the memorialization of astronauts in contemporary America.