Parents are most concerned that their children will contract ear infections, according to a study that appeared in the September 1991 Clinical Pediatrics. Parents also are especially worried that their children watch too much television. These two findings are among the many worries parents have about their children, according to the study.


The first half of the 2000s was characterised by unprecedented political reform in Turkey encouraged by the prospects of EU membership. These reforms helped to improve the quality of democracy as well as the cultural rights of the Kurdish minority in the country. Yet, the Kurdish problem remains far from being resolved. The paper argues that it is, at least partly, the European Union that bears responsibility for the failure of the government's Kurdish 'opening', which, when launched in the summer of 2009, had aspired to solve the Kurdish problem in Turkey.


In the present study, it is shown that in vivo oral administration of
glibenclamide (1-10 mg/kg/day), an adenosine triphosphate -sensitive
potassium channel blocker, and yohimbine (1-5 mg/kg/day), an alpha
2-adrenoceptor antagonist, potently reduced glycemia in male rats.
Diazoxide (1-45 mg/kg/day), a potassium channel opener, and clonidine
(0.05-0.5 mg/kg/day), an alpha 2- adrenoceptor agonist, antagonized the
effects of glibenclamide and yohimbine respectively. Administration of
glibenclamide and yohimbine separately decreased the serum glucose
levels, so it was expected that coadministration of these two drugs
significantly decreased this parameter in fasted animals. It is well
known that glibenclamide blocks the potassium channels and it is likely
that, yohimbine also blocks these channels, but according to our data,
it seems that yohimbine acts via a different binding site to that of
glibenclamide. In this research it is also observed that administration
of yohimbine and glibenclamide causes death in rats,, it seems that
these drugs causes death in the experimental animals by lowering blood
glucose level, which were the aim of this study and could be applied as
a way to control the environmental health by abolishing rats.


The article is close connected with building flying object, that fly like an insect (entomopter). Present work concerns on concept of aerodynamic model using artificial neural networks. Model is used in simulations of flight of entomopter. Aerodynamic model based on experimental data. Necessary data are taken from experiment performed in water tunnel on entomopter model. For this case dynamic test are required. Measurements are ducted during sinusoidal motion of whole model. Modelled object is dipterous. Each wing can perform various spherical motions (wing is rotated around point). The motion of the wing in this case was two-dimensional; it was rotated around two axis. As a model, specially trained neural network is used. For training are used data from measurement. Presented in this article approach is based on artificial neural networks. In this article, innovative concept of model, describing unsteady aerodynamics of entomopter was proposed. It was shown that it could be easily implemented as mathematical model. Unsteady effects related to many state variables can be easily captured. Model can be easily adopted to predict different states of flight by networks training on appropriate data. Test has to reproduce real conditions as close, as it is possible. In reality, it is challenging to design test that will reproduce similar motion.


As a branch of digital watermarking technology,digital fingerprinting is used to trace the leakage of the multimedia content.It becomes a hot topic in recent years.Because of the increase of users and the requirements of video fingerprint application,the fingerprinting system calls for improvements in fingerprint algorithm,such as robustness,collusion-resistance,and real-time processing,which are problems in current research.To lower the computational complexity of fingerprint embedding,we propose a spatial-domain based robust real-time embedding algorithm in this paper.At first,the fingerprints are converted into an embedding template.And then,the template is superimposed to the host signal directly in spatial domain.The proposed embedding algorithm is simple and efficient, and it could be used in various types of multimedia data.Though the fingerprint template is added in spatial domain,the efficiency is equivalent to that of the methods in DFT(Discrete Fourier Transform) domain.Therefore,the robustness can be maintained.Comparing with the traditional algorithms in transform-domain,the proposed algorithm performs much better in real-time processing.This is because that no transformation is needed for video frames or images during the embedding process of the fingerprints.The experimental results show that the proposed algorithm has many advantages in real-time processing and robustness.


Summary The use of Privine has been described for inhibiting the coronary flow of feline hearts perfused by the method of Langendorff. This permits a quantitative evaluation of the activity of coronary vasodilators in that majority of perfused hearts that exhibit such a rapid spontaneous coronary flow that its augmentation is difficult, if not impossible. Under the conditions described the Privine does not alter the cardiac rate or the amplitude of the myocardial excursions.


This article reports a unique analysis of private engagements by an activist fund. It is based on data made available to us by Hermes, the fund manager owned by the British Telecom Pension Scheme (BTPS), on engagements with management in companies targeted by its U.K. Focus Fund (HUKFF). In contrast with most previous studies of activism, we report that the fund executes shareholder activism predominantly through private interventions that would be unobservable in studies purely relying on public information. The fund substantially outperforms benchmarks and we estimate that abnormal returns are largely associated with engagements rather than stock picking. We categorize the engagements and measure their impact on the returns of target companies and the fund. We find that Hermes frequently seeks and achieves significant changes in the company's strategy including refocusing on the core business and returning cash to shareholders, and changes in the executive management including the replacement of the CEO or chairmen.


The goal of this study was to assess the effect of training programme on the healthcare expenses of the households under BRAC's microcredit programme. This study showed that training played a significant role in improving the healthcare expenditure of the household. Other socioeconomic variables such as household income, family size, age of the borrower, non‐institutional loan received by borrowers, amount of microcredit received from BRAC by borrowers, amount of loan instalment and distance of rural market from the borrowers' house were also appeared as the key determinants of households' healthcare expenditure. Copyright © 2015 John Wiley & Sons, Ltd.


Use of extracts containing phytoestrogens exclusively of Vitex agnus castus for the production of a medicament for selectively modulating the estrogen receptor beta without uterotrophic effect, characterized in that the selective modulation of the estrogen receptor beta is used to treat clinical conditions and states pathophysiological - obesity and by this the possible influence the metabolic syndrome, particularly hypertension, arteriosclerosis, myocardial infarction, hyperandrogenism, the extracts may be produced by ethanol extraction.


We discuss the impact of heavy-flavor production measurements in semi-inclusive deep inelastic scattering at HERA on the CTEQ-TEA PDFs.
In particular, we study the impact of the latest charm and bottom production measurements from the H1 and ZEUS collaborations on the gluon,
and the interplay of these measurements with the data ensemble of the recent CT18 global QCD analysis.


"The European Union will be nothing if not multicultural." This slogan puts multiculturalism in a global and legal perspective. Multiculturalism is defined here as the major feature of a society, which is predominantly composed of groups with different ethnic, geographic, religious and cultural roots striving for equal positions among its citizens on the market of labor, goods and capital. The legal support system is based upon the concept of solidarity. Its realization, however, clashes in an exemplary manner with formal requirements of law and administration in the EU.


Purpose: To assess the surgical and clinical outcomes of anterior lamellar keratoplasty using anterior corneal buttons from Descemet stripping automated endothelial keratoplasty (DSAEK) donor tissue. Methods: Retrospective data from 8 patients with unilateral limbal dermoids, treated between February 2011 and January 2016 at National Taiwan University Hospital, were analyzed. Donor corneas for DSAEK were divided into anterior and posterior lamellae using a 350-&mgr;m microkeratome. Anterior corneal buttons were stored for up to 4 weeks in storage media before being used as patch grafts for anterior lamellar keratoplasty. Results: Corneoscleral integrity was preserved in all cases. Three of the 8 patients showed improved best-corrected visual acuity after surgery. Three patients' astigmatism reduced by more than 0.75 diopters. All 8 patients had satisfactory cosmesis after surgery. Neovascularization at the graft–host junction and graft edema was noted in 1 patient and was treated using bevacizumab injection and topical steroid. Conclusions: Anterior corneal buttons obtained from DSAEK can be used as patch grafts for surgical management of limbal dermoids. This procedure achieved satisfactory cosmetic and visual outcomes in our study. This procedure may potentially allow one corneal tissue to be received by multiple patients.


Employment guidance in colleges increasingly stands out due to grave employment situation and dislocation of talents training patterns.The one-sidedness,monotony and scattering of current employment guidance lead to deviation and weakening of the focus in employment work.An integral,systematic and oriented multi-dimensional system is needed to construct and support employment guidance work.Therefore,on the basis of advanced employment guidance system both home and abroad,the thesis puts forward a new idea on how to construct multi-dimensional employment guidance system for university students in order to further improve employment guidance.


Privatization in the telecommunications sector is a growing international phenomenon. Unlike the United States, telephone service in the vast majority of countries has long been provided exclusively by government-owned and operated entities under monopolistic market structures. The classic problem in develop country is the limited ability of the government to provide sufficient funds to finance the development of the telecommunications sector. The initial approach of the Indonesian government to resolve this issue was by partial privatization of the shares of TELKOM and INDOSAT, which was achieved by listing the companies' shares in the local and international stock exchanges, in 1994 and 1995 respectively. Privatization of Indonesian telecommunications state-owned companies such as TELKOM and INDOSAT is a key component of the Indonesian government's economic policy. Indonesia as a member of WTO has a commitment in telecommunications services. Indonesia committed to terminate the exclusive rights: exclusivity expires in 2011 for local service; in 2006 for long distance service, and in 2005 for international service.


A new variant of the mountain pass theorem based on a 'strong' deformation lemma is presented. Some applications to the existence of non-trivial solutions of nonlinear Hammerstein integral equations are given too.


A high quality software architecture facilitates development of a high quality software system. To design such architecture, the software architect must consider multiple stakeholders' partially understood and contradictory objectives, and balance the myriad tradeoffs among them. This research examines how to support this explorative software architecture design process. It identifies the important quality attributes to be addressed, and compares the ultimate architecture design alternatives to make the right decisions to address and balance various stakeholders' needs. Contributions include a new model of "separation of concerns" that addresses quality attributes as first-class elements during software design; a new software architecture design process that focuses on important and unresolved requirements arising from conflicting quality attributes; and adaptation of multiple objective decision theory to software engineering, together with software analysis methods that quantify and balance previously incomparable quality attributes; Evaluations demonstrate its effectiveness on understanding and evaluating quality attributes, and analyzing the design alternatives during architecture design process.


A field experiment was conducted during rabi 1999–00 and kharif 2000 to evaluate the performance of two large seeded groundnut varieties (B95 and GG5) under two land configuration systems (broad bed and furrows and flat bed) and four nutrient management practices (recommended dose of NP, recommended dose of NPK, recommended dose of NPK + gypsum @ 500 kg/ha, recommended dose of NPK + gypsum @ 500 kg/ha + ZnSO4 @ 25 kg/ha). The results revealed that there was no significant variation in pod yield between these two varieties though the two varieties differed significantly in respect of yield attributes. Flat bed system of configuration registered the maximum values of yield attributes and pod yield as compared to broad bed and furrows. Among the different nutrients, application of recommended dose of NPK + gypsum @ 500 kg/ha + ZnSO4 @ 25 kg/ha had higher pod yield which was comparable with the yield obtained under recommended dose of NPK + gypsum @ 500 kg/ha. However the BCR was highest with application of recommended dose of NPK + gypsum @ 500 kg/ha.


A series of 84 biomass sampling plots were established in 2 to 10-year-old black locust stands in order to determine total energy content and usable energy content of the above ground biomass. Average whole-tree heats of combustion ranged from 8600 to 8539 Btu/lb for 2 and 10-year-old stands, respectively. Average energy contents with the 2-year-old stands containing less energy than 10-year-old stands, 8357 and 8440 Btu/lb, respectively. Total energy contents were lowest in 2-year-old stands averaging 82.5 and 50.9 MBtu/ha for total above ground and woody biomass, respectively, while nine-year-old stands yielded the highest amount of energy upon combustion 655.3 and 576.9 MBtu/ha for above ground and woody biomass, respectively. Usable energy contents (total energy content minus energy losses attributed to combustion in a boiler system) ranged from 56.7 to 470.4 MBtu/ha for 2 to 10-year-old whole-tree biomass. Nine-year-old stands exhibited the highest usable heat content 483.4 MBtu/ha for whole-tree biomass and 432.8 MBtu/ha for woody biomass. Annual usable energy contents were again highest for the total and woody biomass of 9-year-old stands, 53.7 and 48.1 MBtu/ha, respectively.


This study was performed to investigate source and drinking waters in term of coliform group and Escherichia coli of Van and province. 24 natural springs and 176 public drinking water supply distribution sys- tems a total of 200 samples were collected. The membrane filter (MF) method were used for detection and enu- meration of coliform bacteria and E. coli in drinking water. Coliforms and E. coli in drinking water samples collected from different sources were found in the rate 17.5 % and 10 % respectively.


This research focuses on the Qur'ānic approaches in caring persons with special needs; their education, religious, health, moral, psychological as well as social rights. The aim of this research was discovering the rights of persons with special needs in the Holy Qur'ān. As a result, the research attains the verse 24:61 talks regarding rights of this group of people. It highlights what to care, who is responsible for caring them, what are the methods used, and the aspects of their care. The Qur'ān does not use the word 'disable'. It uses the blind, daft, lame, and sick to establish their rights in family and society in a country.


In mission critical applications, all critical points (CPs) are to be monitored effectively. Even a single node failure in the Wireless Sensor Network (WSN) may cause coverage hole, reducing the lifetime of the network. The sensor has nonrechargeable battery which makes energy supervision inevitable. The proposed Energy Efficient Coverage based Artificial Bee Colony Optimization (EEC-ABC) approach exploits intelligent foraging behaviour of honeybee swarm to solve Energy Efficient Coverage (EEC) problem, and thereby maximizes the network's life time. It adheres to Quality of Service (QoS) metrics such as coverage, residual energy and life time. The simulation results demonstrated effectiveness of the residual energy and coverage in enhancing network lifetime.


The combination of direct and indirect rule in Africa during late colonialism created a dual state where, broadly speaking, rural areas were under indirect rule through chiefs while urban areas were subject to direct rule. This article explores the developments that in Malawi have led to a state in which most individuals are exposed to both forms of rule simultaneously. Nowadays, people in most areas experience two parallel state organisations, and individuals are simultaneously citizens of the state and subjects under a state-enforced chieftaincy system. Recently indirect rule has also experienced institutional expansion: the chiefly hierarchy, which previously reached only to district level, now extends all the way to the president, making the choice between the two parallel organisations relevant at higher levels of the state hierarchy. For those able to straddle the two forms of rule, this means a wider scope of opportunities for interacting with the state. Yet, for others it means a dissonance between the rhetoric of civil, rights-based governance and the practice of chiefly rule. For state agencies, it makes available more options for effective governance, and the president in particular can choose between two separate institutional hierarchies in the execution of state power. For academic studies, the case of Malawi demonstrates that research on state building and governance should not equate bureaucratic capacity with state capacity. The chieftaincy, standing outside the bureaucracy, constitutes a key component of state power and everyday governance, and it is difficult to imagine it being replaced by any part of the formal government in the foreseeable future.


Supervisory Committee Dr. Sibylle Artz, School of Child and Youth Care Supervisor Dr. Marie Hoskins, School of Child and Youth Care Departmental Member This study describes the reasons why street children in Jakarta, Indonesia choose to leave a life on the street and the steps that are taken to exit the street successfully. Also described are the street entry process, life on the street, street disengagement, life after the street, and the role of service providers. Nine key informants (six former street children and three workers who work with homeless children) participated in in-depth interviews that revealed that troubled family life is the most common cause of street entry, and while street life offers much freedom and excitement it is also the source of great danger to street children, and street disengagement often takes a number of attempts before a "successful" exit is fully negotiated. Forming trusting relationships with streetbased outreach workers and attending NGOs that emphasize love and care were highly influential in aiding with street exit. Also key to a successful exit over time is the development of new skills and knowledge, as well as a positive sense of self and an identity that is not connected to street involvement.


This paper presents and compares the results of Artificial Neural Network (ANN) classifier, Support Vector Machine (SVM) classifier and K nearest neighbor (KNN) classifier in diagnosing Myocardial Ischemic beats from ECG signal. The input features for the classifiers are obtained by feature extraction techniques based on morphology, statistical parameters, principal component analysis (PCA) and independent component analysis (ICA) of ECG beat. The performance of all classifier models are validated and compared on ECG signal acquired from physiobank database in terms of positive prediction accuracy, classification accuracy and sensitivity. The experimental results have confirmed that highest testing classification accuracy of 96.85% is resulted from ANN classifier model. This signifies that the ANN based model has immense potential than SVM and KNN classifiers in diagnosing myocardial ischemia.


The Middle East-North Africa (MENA) is one of the official CORDEX domains, since it offers considerable challenges due to its large size, complex topography and great climate variability. Several modeling groups are currently perf01ming dynamical downscaling of eight CMIP5 GCMs, employing spatial resolution of 0.75°, 0.44° and 0.22°. In this study, the ca pabilities of the regional climate model COSMO-CLM in reproducing the main climate features of the MENA-CORDEX domain have been assessed. Two ERA-Interim driven simulat ions were performed, respectively at 0.44° and 0.22° spatial resolution for the period 1979-2011. Model configuration was chosen on the basis of a sensitivity study aimed to ascetiain model performances with respect to changes in physical and tuning parameters. Model response has been analyzed in terms of low-level circulation, 2-meter temperature, precipitation and cloud cover. Evaluation was conducted with respect to a combination of available ground obsetvations, satellite products and reanalysis, since wide areas are characterized by a scarce number of ga uge stations. Results reveal that the values of the considered variables are generally in good agreement with observations, confirming that the albedo and aerosol parameterizati ons adopted lead to a remarkable improvement in model performances. Effects of increasing spatial resolution have also been investigated. Moreover, within a collaboration with the University of Tel Aviv, a high resolution simulation (0.0715°) has been performed over Israel, nested into the 0.22° simulation over MENA domain; results have been evaluated against an observational dataset provided by Israeli meteorological service.


The School Progression Policy is an intervention strategy to decrease unnecessary, high dropout rates in the South African Education system. It allows learners to move from one grade to another and thus advance in their careers and exit the basic education school system with a qualification. However, due to this intervention, some learners have experienced social and emotional problems at school, which may affect their well-being. This study explored the effects of the School Progression Policy on the progressed Grade 12 learners' well-being in schools. It adopted a qualitative research methodology within a constructivist paradigm and used a case study research design. Thirty-seven learners (23 females and 14 males) and fifteen teachers and SMTs were purposively selected from four schools in the Motheo Education District. Semi-structured interviews were employed for data collection. Thematic results revealed that this policy implementation positively and negatively affected progressed Grade 12 learners' well-being. This study recommended constant empowerment and motivation for the progressed learners and comprehensive orientation at the beginning of the year to prepare and capacitate them to handle the expectations and challenges of Grade 12.

Keywords: School Progression Policy, Progressed Grade 12 learners, Retention, Learners' well-being


Currently, the priority of postgraduate education is the preparation of specialists with a sufficient level of knowledge of a foreign language for the successful exchange of both scientific and technical achievements through inter-lingual channels. Foreign language competence is a prerequisite for professional development of a specialist, and knowledge of a professionally oriented foreign language as a means of intercultural communication will allow a prospective specialist to build the basis of their personal and social life with practical skills and abilities and implement them in professional activities. This allows us to highlight the importance and necessity of a foreign language competence development in the sphere of public administration. Competence development process should be based on authentic materials and account for situations of real-life professional interaction of the specialists that leads to the relevance of the study, which aims to define the criteria of selection of the speech material for teaching English for specific purposes. This aim led to the use of theoretical research methods (studying philosophical, linguistic, psychological, didactic and methodological papers to understand the problem, developing theoretical foundations and conceptual approaches to the development of program material) and empirical ones (scientific observation of teaching a professionally oriented foreign language to public administrators). The article also outlines the importance of the development of professionally-oriented foreign language competence for the public administrators, highlights the main requirements for the candidates for public service positions in the European space, and discovers educational processes in the framework of postgraduate education in Ukraine. The authors define the unit of selection of teaching material and describe the procedure of its selection as well as the conditions of the development of foreign language competence for professional purposes.


The non-technical energy losses reduction strategies have stimulated the development of centralized metering systems (cms) in Latin America. Furthermore to include ami systems basic functions, the cms embed the measurement of multiple users in a cabinet. To avoid the utility customers getting access to the energy meter, each cabinet is mounted on top of an electrical pole. Currently, the major commercially available cms equipment is setting up with several technologies, which involves owner interfaces and data models. This issue generates an interoperability problem since international standards are based on measurement architectures for the use of individual meters. This paper proposes a set of both information exchange protocols and standardized data models that could be implemented in cms equipments.


The present invention relates to a production method of yogurt containing fermented red pepper powder. The production method of the yogurt containing the fermented red pepper powder comprises the following steps: adding red pepper powder into a bacillus initial medium, and injecting Bacillus lichenifomis SK1230 strains before culturing the mixture to obtain the fermented red pepper powder; and adding the fermented red pepper powder into fermented milk. [Reference numerals] (AA) 0.3% Cheongyang red pepper Glucose (-);(BB) 0.3% Cheongyang red pepper Glucose (+);(CC) 1% Cheongyang red pepper Glucose (-);(DD) 1% Cheongyang red pepper Glucose (+);(EE) 3% Cheongyang red pepper Glucose (-);(FF) 3% Cheongyang red pepper Glucose (+)


The hot radiating gases formed during normal combustion in liquid‐fuel rocket motors are responsible for radiant heat transfer to the chamber walls and to the liquid or gaseous reactants which are injected at the head end of the rocket chamber.


Electro-hydrostatic Actuation Systems (EAS) successfully combine the advantages of electro-mechanical actuation - such as high-energy efficiency and low noise emission - with the benefits of electro-hydraulic technology – which include robustness and the precise handling of large forces. This paper defines keywords like EAS and Electro-hydraulic pump unit (EPU), and provides a comparison of the two technologies. Given the wide range of EAS technology topics, it is only possible to briefly introduce and discuss these in this paper. This technology has reached a level that renders it a strong mechanism for machine manufacturers to support existing and future motion control requirements.


A retrospective case notes review was performed to determine compliance with screening for undetected pregnancy prior to commencement of chemotherapy at Flinders Medical Centre. All female patients aged 18–55 who commenced chemotherapy between January and December 2014 were included. During the first 12 months, for women identified as having childbearing potential, pre‐chemotherapy pregnancy screening was performed only in 40% of patients under 40 years and in 20.5% of the entire age range.


Next the career of a football player is described from the beginning (the important support of the parents) and through the stages of the development (learning skills in a group) and the establishment, with the many important turning-points: making the team, getting injured, receiving an award and other critical events or decisions. Opposed to most careers a football-career has also a declined stage and ultimately leaving the world of football seems to be difficult for every athlete: for stars but also for players who had a more ordinary career.


As a fast and reliable technology with applications in diverse biological studies, cell-free protein synthesis has become popular in recent decades. The cell-free protein synthesis system can be considered a complex chemical reaction system that is also open to exogenous manipulation, including that which could otherwise potentially harm the cell's viability. On the other hand, since the technology depends on the cell lysates by which genetic information is transformed into active proteins, the whole system resembles the cell to some extent. These features make cell-free protein synthesis a valuable addition to synthetic biology technologies, expediting the design–build–test–learn cycle of synthetic biology routines. While the system has traditionally been used to synthesize one protein product from one gene addition, recent studies have employed multiple gene products in order to, for example, develop novel bacteriophages, viral particles, or synthetic metabolisms. Thus, we would like to review recent advancements in applying cell-free protein synthesis technology to synthetic biology, with an emphasis on multiple gene expressions.


We present a GPU (graphics processing unit) accelerated stochastic algorithm implementation for simulating biochemical reaction networks using the latest NVidia architecture. To effectively utilize the massive parallelism offered by the NVidia Pascal hardware, we apply a set of performance tuning methods and guidelines such as exploiting the architecture's memory hierarchy in our algorithm implementation. Based on our experimentation results as well as comparative analysis using CPU-based implementations, we report our initial experiences on the performance of modern GPUs in the context of scientific computing. key words: GPU computing, parallel programming, stochastic simulation


This is to certify that the thesis entitled "STUDIES ON THE EFFECT OF NICKEL AND MANGANESE DOPING ON THE PROPERTIES OF ZINC OXIDE THIN FILMS FOR GAS SENSOR APPLICATIONS" submitted by M. KARUNAKARAN for the award of DOCTOR OF PHILOSOPHY is a record of research work done by him, under my guidance and supervision during the period 2007 to 2012 and the thesis has not formed the basis for the award to the scholar of any Degree, Diploma, Associationship, Fellowship or any other similar title of any University or Institution. Also certified that the thesis represents an independent work on the part of the candidate.


The content of trace elements in the hair of 239 children from Jiaoyueheng kindergarten of Xinyi city was investigated,of 239 children,165 were males and 74 were females.The inductively coupled plasma atomic emission spectroscopy (ICP-AEP) was used to detect the content of trace elements such as Ca,Zn,Fe,Cu,Mn and Pb.The results showed that the content of Ca was (584.84±178.76)μg/g,Zn was (178.10±83.38)μg/g,Fe was (61.67±17.49)μg/g,Cu was (14.03±8.92)μg/g.Mn was (2.86±1.73)μg/g and Pb was (7.13±2.83)μg/g.Evaluated by the four-degree ranking criteria issued by World Health Organization (WHO),middle-degree or above malnutrition of Ca,Zn and Mn was not found in the children,but 0.4% of the children were affected by severe malnutrition of Fe,and 8.0% affected by middle-degree malnutrition of Cu.The content of Pb did not exceed the middle-degree standard.The comparison results showed that the content of trace elements in children from Jiaoyueheng kindergarten of Xinyi city was superior to those from the kindergartens of the surrounding cities.It is suggested that the contents of trace elements should be used as one parameter for the comprehensive quality evaluatio of kindergartens.


A 10-year-old white boy presented clinically with thalassemia major facies, pallor, jaundice, and hepatomegaly. Investigation revealed the patient has hemoglobin (Hb) Lufkin concurrent with β0 thalassemia. DNA sequencing of the β globin gene confirmed a GGC to a GAC mutation at codon 29 (gly to asp) for Hb Lufkin on the patient and also revealed a β0 thalassemia mutation, IVS-1-1 (G to A), on both the patient and his mother. Both parents lack the Hb Lufkin mutation. Molecular studies, human leukocyte antigen, and red blood cells phenotypic studies indicate spontaneous mutation of Hb Lufkin in this patient.


A simple scheme for direction of arrival (DOA) estimation of coherent targets in a multiple-input multiple-output (MIMO) radar is proposed. It is based on the idea of joint transmission and reception diversity smoothing. Compared to the existing transmission diversity smoothing (TDS) method, the major advantage of the new scheme is that more covariance matrices are available for averaging to decorrelate the coherent signals, leading to a better estimation result. Moreover, it is able to identify much more coherent targets than the TDS method when sparse arrays are used.


This paper analyzed the characteristics of the case teaching and the traditional teaching method.Through the analysis of the role of case teaching in cultivating students' innovative consciousness and innovative ability,improving students' abilities of analyzing and solving problems and the ability of integrated use of knowledge.This paper inquires into the conception of case teaching method in mathematics teaching of independent college.


Traditional NSSA (network security situational awareness) systems have significant equipment limitations, poor data fusion capabilities, and a low level of analysis and evaluation, making them difficult to adapt to large-scale and complex network environments. This paper proposes the study of computer NSS (network security situation) prediction technology based on AR (association rules) mining to solve this problem. The support-confidence framework is improved by introducing an interest evaluation standard, and the value of AR is re-evaluated, based on a discussion of traditional concepts and algorithms related to AR mining. The MFP-interest algorithm proposed in this paper is a combination of alarm AR template and interest degree. The MFP-interest algorithm was put to the test. We discovered that the MFP-interest algorithm can effectively predict NSS and indicate its development trend when run in a real-world network environment. Most time points have a relative error range of less than 0.035.


The adjective sustainable, both in general and when applied to architectura, involves the consideration of environmental, economic and social aspects. However, advances in research on sustainability in the last decade have confirmed the need to incorporate a new approach to what we understand as basic: Ethics. The dimensions of current approaches in sustainable architecture widely surpass those usually analysed which are based on time and space. The definition of sustainability in itself, as a link between generations, expands the time coordinate: the research and activity of architecture includes much more than the project itself or a building's useful lifespan. The space coordinate has also widely surpassed the limits that have been used up to now: the idea of thinking globally and acting locally expands the locus of architectonic design on to the planet as a whole. These new limits of building horizontally-the whole planet, and vertically throughout generations to come, makes ethics the base, the fundamental and the field from which we should study sustainability. First, we must establish the rules that will guide the analysis: Ethics are understood as the study of what is good and bad, proper and improper in accordance with the norms set by society at a given time. Sustainable architecture and methods of evaluating the environment's behaviour of current buildings is moving towards this field, even though unconsciously. lt is important to think about sustainability's reasons and original framework in order to exactly understand what are the aims and scope in which it is developed. The study of sustainability in architecture from an ethical point of view determines the criteria under which the evaluative methods should evolve, noting the ways for proper development.


A specific method to detect fipronil in postmortem samples with solid phase extraction is presented. For sample clean up a simple but selective solid phase extraction is chosen. Elution was done with 1: 1 mixture of dichloromethane and ethyl acetate. Fipronil was detected in stomach tissue and in blood sample. For LCMS gradient elution with a mixture of acetonitrile and water was used. The column was Hypersil Gold. This method is applied to a suicidal case involving intoxication with Fipronil.


Safety of aircraft during the flight is one of the most important problems that concerns of all aviation. Failures/faults main elements automatic control system and damages to the external contour of the aircraft by foreign objects always lead to a change the characteristics of the aircraft, direct and indirect economic costs and sometimes to injury or death of passengers and crew. Real-time active fault tolerant control system makes it possible to warn or prevent emergency situations and thus improve safety.


Nowadays, BERT models have found wide use in the NLP field. However, standard BERT architecture training can be stifled by the lack of labels for different tasks while treating multitask settings as a one-task multilabel setting. For every example, we have labels from this example's source task but not from other tasks. This article addressed this issue, exploring eight different data pseudo-labeling approaches in the GLUE 4-task setting. These approaches do not require changes in samples or model architecture. One of the presented techniques excels results on RTE from the original article, by 6.2 %, and falls behind the original article on QQP, MNLI, and SST only by 0.5-1.2 %. This way also excels other pseudo-labeling approaches explored in the article by 0.5-2% on average if we consider similar tasks. However, for tasks that are dissimilar to each other, different proposed approach yields the best results.


This study assesses the prognosis of bone tumor chemotherapy. The expressions of P53 and NM23 were measured to analyze their relationship. The curative effect distributions of patients with positive and negative expression of P53 were not the same (x2 =10.513, P
 =0.016). P53 positive level was associated with nausea and vomiting (x2 = 18.664, P <0.05), oral mucositis (x2 = 23.346, P <0.05) and diarrhea (x2 = 16.514, P < 0.05), as well as incidence of complications.
 The 3-year survival rate was 38.3% for patients with P53 positive level and 31.4% for patients with negative, with a significant difference (Log rank x2 = 6.417, P = 0.011, HR = 1.784, 95%CI: 1.084–2.936). Adjuvant chemotherapy is an important treatment for osteosarcoma,
 but it has not achieved satisfactory outcomes in terms of improving the prognosis, and there are still problems of high recurrence and metastasis rates after surgery. After osteosarcoma treatment, it is faced tumor recurrence and metastasis and bone repair. The precise exploration of prognostic
 targets participates in this disease. This study thus explored the prognosis of two important tumor suppressor genes, and herein results showed that, the expression of human tumor suppressor gene P53 has an important effect on bone tumor patients receiving Folinic acid, fluorouracil and oxaliplatin
 (FOLFOX). The curative effect and safety of chemotherapy have a certain predictive effect, and play an important guiding role in tumor metastasis and recurrence after treatment, among which P53 can also predict the mid-term survival of patients.


Moment Lyapunov exponents are important characteristic numbers for describing the dynamic stability of a stochastic system. When the pth moment Lyapunov exponent is negative, the pth moment of the solution of the stochastic system is stable. Monte Carlo simulation approaches complement approximate analytical methods in the determination of moment Lyapunov exponents and provides criteria on assessing the accuracy of approximate analytical results. For stochastic dynamical systems described by Ito stochastic differential equations, the solutions are diffusion processes and their variances may increase with time. Due to the large variances of the solutions and round-off errors, bias errors in the simulation of moment Lyapunov exponents are significant in improper numerical algorithms. An improved algorithm for simulating the moment Lyapunov exponents of linear homogeneous stochastic systems is presented in this paper.


A survey was conducted in Vienna in 2002 to get answers to questions concerning the target audience for subtitled films.


This study aims at defining the medical tourism marketing obstacles and challenges facing Spas in the Dead Sea from the touristsi¯ point of view. The study sample consists of 86 Jordanian tourists and Arab Countries citizens. The researcher used the analytical descriptive method. Medical tourism marketing scale has been adopted and developed from the relevant previous studies. The study suggests that the medical tourism marketing facing the Spas in the Dead Sea Region from the touristsi¯ point of view are medium, and there is no statistically significant differences ascribed to gender and educational levels variables.


Objective To study the changes of total antioxidant capacity, antioxidase activity and the production of inflammatory mediators and investigate the relationship between TAC IL 6 and iNOS mRNA expression in aged rats. Methods The levels of TAC, SOD, GSH Px and NO in serum, brain, heart, liver and kidney were measured by biochemical methods. The expressions of IL 6 and iNOS mRNA in blood and organs were detected by RT PCR(18 months rats as aged group and 2 months rats as control group). Results The levels of TAC, SOD, GSH Px in serum and organs were significantly lower in the aged group than those in the control group. The production of NO and the [xxk1] expressions of IL 6, iNOS mRNA were higher than those in the control group. The higher expressions of IL 6, iNOS mRNA were negatively correlated with the levels of TAC in the aged group. Conclusion The TAC level is significantly lower in the aged rats, which is correlated with the higher expression of IL 6, iNOS mRNA. It has been demonstrated that there are high oxygen stress and inflammatory response in old rats, which may cause the autodamage of the tissues. It also implies that antioxidant therapy will enhance the level of TAC and downregulate the oxygen stress and inflammatory response.


Mechanism for producing cusp magnetic field is studied. The physical model of cusp magnetic field has been set up with the amendment of the Moster-Molnar model. Based on the cusp magnetic field theory analysis and numerical simulation, factors that influence the cusp magnetic field design have been discussed. The Lagrangian formulation is used to solve the electron trajectories in some simple magnetic cusp configurations. The relationship between the cusp magnetic field and the large orbit gyrotron hollow cusp electron gun has been explored, and some general conclusions have been presented on the prospects of generation and improvement of the big orbit cusp electron gun.


Background

Health systems in France and Germany are facing comparable challenges and have recently adopted similar policies to improve quality of care. A policy innovation widely implemented in Anglo-Saxon countries is pay-for-performance (P4P), payment schemes in form of bonuses that align payments with payers' goals for quality improvement. While P4P has been implemented in France since 2009, Germany is currently debating the introduction on a …


This volume presents the experimental and theoreticl methods of studying soft interaction physics in high energy collisions. The topics include: dynamical and Bose-Einstein correlations, multiplicity fluctuation, soft photons, disoriented chiral condensate, self-similarity and self-affine behaviours, wavelet analysis, intermittency, chaos, and phase transition.


Background: Fusions (Fs) are major molecular biological abnormalities in acute leukemias (ALs), and all well-known Fs in leukemias are founder variations are routinely used as molecular markers for the diagnosis, classification, risk stratification, and targeted therapy but there is a considerable part of ALs that are not screened for other known/unknown transcripts. For example in B-Other B Acute Lymphoblastic Leukemia (B-ALL) [Ph-/-/-; negative for t(9;22); t(1;19); t(4;11); 61% of adult B-ALL], many chimeric genes have been identified leading to a refined classification of B-ALL and to, in some cases, tailored therapies. At this point, a RNA-seq approach is needed but challenging for many aspects, among them a not standardized and very heterogeneous F data analysis.
 Aims: We developed and validated our integrated pipeline in order to assess targetable biomarkers and to better classify patients (pts).
 Methods: we performed 1385 gene RNAseq (Illumina) of 224 adult AL samples (112 Ph-/-/-, 41 Ph+, 6 t(1;19), 16 T-LBL/T-ALL and 49 AML). Starting from Ph-/-/-, we developed a combined 4 tool analysis that is further implemented with a filtering strategy with a specific ALs fusion literature filter (Patent PCTEP2021-065692 and 749 ALL Fs database copyright) (Fig.1A). We validate our strategy using: RT-PCR, FISH SNP Arrays; MLPA and total RNA-seq.
 Results: From 3022 candidate Fs, we retained 160 of them (5.3%; excluding WHO canonical Fs) not otherwise detected, in 120 pts with a high Fs rate in T-LBL/T-ALL, Ph-/-/- and Ph+ (62.5%, 62.2% and 61% respectively) denoting that ALs are not deeply characterized (Fig 1B). The lower rate was found in AML (26.5%), but we were able to identify new ETV6 rearrangement (r) and a FISH cryptic F in a 46, XY pt (TBL1XR1-MECOM). We validated 98 Fs that have been already reported in the literature and 43 novel F transcripts. We obtained a validation rate of 81%. The majority of fused samples (65.2%) had only one detectable F while a smaller group was characterized by multiple Fs. Many of these Fs were previously described in B/T-ALL and AML (e.g. KMT2A-MLLT1, ABL1/2-RCSD1, IGH-MYC, NUP214-SET, ETV6-MECOM). In our bigger sub-cohort (Ph-/-/-), 44 Fs out of 109 (40.3%) were never been reported in Ph- ALL cases. In 15 Ph-like pts, we identified and validate 11 new transcripts. Ph-/-/- F detection help to sub-classify our fused pts in Ph-/-/- subgroups (ZNF384r-11.8%; Ph-like-19.1%; DUX4r- 4.4%; HLFr, MLLr and BCL2/MYC in 2.9%; MEF2Dr-1.5%).
 Conclusions: we identified pivotal transcripts in all ALs and an unexpected high rate of secondary Fs in adult ALs subgroups (52.4%) that are not characterized with conventional diagnostic methods. The use of an NGS approach and a powerful pipeline permit us to detect Fs useful for a better classification, prognostic identification (e.g. TBL1XR1-MECOM) and in some cases to find targetable Fs (e.g. ABL1-2/RCSD1, NUMA1-CSF1R, ZMYM2-FLT3). Supported by: L3P2505.
 Citation Format: Anna Ferrari, Silvia Vitali, Eugenio Fonzi, Andrea Ghelli Luserna Di Rora, Chiara Domizio, Cristina Papayannidis, Maria Teresa Bochicchio, Giovanni Marconi, Daniele Dall'Olio, Michela Tebaldi, Michela Rondoni, Barbara Giannini, Fabio Giglio, Crescenza Pasciolla, Monica Fumagalli, Sara Galimberti, Gastone Castellani, Daniel Remondini, Giorgia Simonetti, Giovanni Martinelli. Fusion landscape in acute leukemias: A submerged world of not routinely characterized transcripts [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 6163.


Rolloff-factor is a key parameter of M-PSK signals. It depicts the bandwidth and envelope fluctuation of the signals. This paper analyzed the effect of rolloff-factor error on the BER performance in the receiver with a theoretical method. The result shows the effect is very small. Computer simulations prove the correction of the derivation. It is useful for the receiver design in non-cooperative communication.


It is known that the signal gain of an array of hydrophones fluctuates randomly in time. Several authors have investigated these fluctuations from different viewpoints; most of them determine meansquare array responses assuming correlated phase fluctuations. Since the signal gain varies with time, it should be regarded as a stochastic process. All attempts to find the multidimensional distribution functions of this process assuming Gaussian inputs have failed. It is not difficult, however, to develop an expression for the power spectrum of the gain fluctuations of the array output in terms of the spectra at the individual hydrophones and the cross spectra between the array elements. Data were taken on the individual elements of an array of five hydrophones and the spectrum of the array‐gain variations was computed in accordance with the procedure to be presented. This spectrum is compared with the spectrum obtained directly from the fluctuations of the array output. It is hoped that measuring array fluctu...


The objectives of this study are to describe the changes in industrial location that have occured in Europe in recent decades; to establish whether these are associated with countries' economic structures becoming more or less similar, and industries becoming more or less spatially concentrated; to compare industrial location patterns in Europe and the US; and to identify the underlying forces that determine industrial location and assess the extent to which these have changed in recent years.


The tradeo between Resolution, Line Edge Roughness (LER) and Sensitivity, the so called RLS tradeo, continues to be a dicult challenge, especially for EUV lithography. Acid ampliers have recently been proposed as a method to improve upon the overall RLS performance of EUV resists. Here we discuss a simulation approach to study the issue. The model extends the standard reaction diusion equation to explicitly capture the stochastic behavior of exposure, photo-acid generation and acid amplication. Using this model the impact acid ampliers have on the RLS tradeo is studied under a variety of resist conditions.


Background: Ribociclib (RIB) is a cyclin-dependent kinase 4/6 (CDK4/6) inhibitor that has demonstrated efficacy and safety in combination with endocrine therapy (ET) for the treatment of advanced breast cancer (ABC), but to date no studies have specifically evaluated RIB in a population in mainland China. This study aims to assess the efficacy and safety of RIB or placebo in combination with ET in premenopausal and postmenopausal Chinese patients with hormone receptor-positive (HR+), human epidermal growth factor receptor-2–negative (HER2−) ABC. It is also designed to investigate the pharmacokinetics (PK) of RIB in combination with ET. Methods: In this phase 2 randomized, double-blind, placebo-controlled study, Chinese women with ABC will be included in a premenopausal or postmenopausal cohort (~150 patients each) and randomized 1:1 in each cohort to receive RIB or placebo. A further ~15 patients will be included in an open-label PK cohort. All patients must have HR+, HER2− ABC based on the most recently analyzed biopsy, with advanced disease not amenable to curative therapy. Patients must have measurable disease per Response Evaluation Criteria in Solid Tumors (version 1.1) or at least 1 predominantly lytic bone lesion, and Eastern Cooperative Oncology Group performance status score (ECOG PS) 12 months from the completion of treatment until randomization. Exclusion criteria include previous CDK4/6 inhibitor therapy; symptomatic visceral disease or any disease burden rendering patients ineligible for ET; central nervous system metastases; known human immunodeficiency virus infection history; and clinically significant uncontrolled heart disease. Patients in the premenopausal cohort will be randomized to 600 mg RIB oral (3 weeks on/1 week off) or placebo, in combination with a nonsteroidal aromatase inhibitor (2.5 mg letrozole [LET] oral or 1 mg anastrozole oral, chosen by investigator) and 3.6 mg goserelin subcutaneous. Patients in the postmenopausal cohort will receive RIB or placebo in combination with LET; those in the single-arm PK cohort will receive RIB in combination with LET. The primary endpoint of the premenopausal and postmenopausal cohorts is progression-free survival. Secondary endpoints are overall survival, overall response rate, clinical benefit rate, time to response, duration of response, and time to deterioration in ECOG PS. The objectives for the PK cohort are to characterize PK parameters of the RIB + LET combination, and of the RIB metabolites. Citation Format: Zhimin Shao, Binghe Zu, Zhongsheng Tong, Qiang Liu, Wei Li, Li Cai, Kunwei Shen, Wenhe Zhao, Jin Yang, Chuan Wang, Woody Tang, Tingting Sun, Yu Han, Ruina Gao. A phase 2 randomized, double-blind, placebo-controlled study of ribociclib or placebo in combination with endocrine therapy for the treatment of premenopausal and postmenopausal Chinese women with HR+, HER2−, advanced breast cancer [abstract]. In: Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr OT2-02-08.


The use of identifying designations has ancient roots, but the development of modern trademark law has more recent origins. Scholars trace early trademark cases to 16th century England. The earliest identified trademark infringement case is Sandforth's Case, which was decided in 1584. Although the opinion in that case is lost to time, another case, Southern v. How, detailed the pertinent facts. In Sandforth's Case, a clothier from Gloucestershire known for the fine quality of his wares used a well-known mark to sell clothing in London and "embody the good-will and fame of his business." The clothier had "made cloths which were more expensive and more saleable than the cloths of any other, and he put a special mark on them which no other clothier had before that." Another clothier had "counterfeited said mark and placed it on his cloths, which were not as good but which he sold at the same price as the other by this deceit; [it] was deemed that the action was against him in this case."


In the present study a multiprogrammable, atriul synchronous, ventricular inhibited pacemaker (Enertrax) was used in six patients. This pacer makes it possible to evaluate pacemaker performance nonmvasively and facilitates the correct interprefation of the djfficult ECGs produced by these complex pacemakers.


Workforce downsizing is associated with a decline in health and a higher likelihood of turnover among employees who remain in the company. Notwithstanding these detrimental effects, there is limite...


Protocols and phenotyping are of central importance for research and for physiological breeding. Quantitative measurements are essential for identifying traits. Gene discovery and QTL analysis depends on accurate phenotyping. This issue of Functional Plant Biology features a protocol for a widely used and well regarded analytical tool in physiological research: measurements of photosynthesis using the LI-COR 6400 leaf gas exchange instrument (Evans and Santiago 2014). This protocol was prepared by two experts in the area of photosynthesis, experts both in conceptual and practical applications of the technique. The protocol was first published in PrometheusWiki (http://prometheuswiki.publish. csiro.au). After favourable comments by users, and thousands of downloads later, this protocol has been awarded the Gold Leaf standard and upgraded from a wiki to a citable publication with a doi (http://dx.doi.org/10.1071/FP10900). PrometheusWiki: PROtocols, METHods, Explanations and Updated Standards Wiki is a web-based, free-content resource built primarily from volunteer contributions (Sack et al. 2010). PrometheusWiki presents an exciting and novel approach to sharing knowledge in the fields of plant physiology and the environmental sciences. It is an open access, fully searchable web resource that contains protocols and methods for plant physiology, crop physiology and ecology. The site is aimed at students and emerging researchers who are looking to develop new research directions, as well as providing a high quality open space for established researchers to debate and develop consensus tools in the field. In the 3 years since its launch PrometheusWiki has achieved the highest regard from colleagues in the field and has more than 1300 registered users, with contributing authors from most countries around the globe. The site hosts more than 500 protocols and expert summaries – the equivalent of many journals in the same timeframe. The site receives an average of 800 unique visitors each week with the most highly accessed protocols receiving more than 3000 visits since posting. Plant scientists are being called upon to solve global problems: looming food crises and the pressure to predict and respond to global change being foremost among these issues. To advance the field most effectively, the latest methods should be shared collaboratively and immediately. Prometheus Wiki is a unique resource that combines the best elements of a traditional journal: peer review and oversight by an expert Editorial Board. It uses the cutting edge of new media and wiki technology, and an intuitive, interactive, customisable interface for discussion and debate. While many traditional journals publish methods papers and many sites provide methods advice, only PrometheusWiki brings together the reputability of a journal and the immediacy of a wiki in one place. Phenotyping for physiological breeding: two new manuals from CIMMYT A two-part manual on 'Physiological Breeding' has recently been published by the International Maize and Wheat Improvement Center (CIMMYT), Mexico. The two volumes focus on wheat, although the principles and methodologies would be relevant to most crop species and even model plants. This provides up-to-date practical information for plant scientists and physiological breeders seeking to apply tried and tested phenotyping approaches in their own programs. While making use of the rapid advance in plant genomics and molecular marker technology, much of wheat breeding is still conducted at the whole plant level using field based protocols. The manual is therefore very relevant to all who work towards crop improvement in wheat and other cereals in particular those working for hot or water-limited environments and regions vulnerable to climatic change. The two volumes outline the criteria for choice of reliable phenotyping methods in the context of the major environmental factors to which crops must adapt. Methods include use of both simple and complex instruments, and the design of large experimental populations to facilitate gene discovery, and of high throughput phenomics platforms. The first volume (http://libcatalog.cimmyt.org/download/ cim/96140.pdf) presents the theory for applying diverse phenotyping tools. It contains chapters on the application of physiology in plant breeding for increases in yield potential, in phosphorus and nitrogen use efficiency, and for the maximum water-limited yield in hot anddry environments. Theprinciples of phenotyping include gas exchange and chlorophyll fluorescence, plant water relations, and genetic diversity in root traits. The second volume (http://libcatalog.cimmyt.org/download/ cim/96144.pdf) provides an overview of diverse wheat phenotyping techniques and provides detailed protocols for applied in-field crop research, with an emphasis on the methods commonly used at CIMMYT's phenotyping platform. This volume provides detailed guidance on the accurate and reliable measurement of physiological traits throughout the wheat crop cycle, along with in-depth notes and advice to assist the reader to use physiological breeding techniques with confidence. Methods and protocols are provided for several single-plant measurements such as photosynthesis, stomatal conductance and carbon-isotope discrimination, and for canopy measurements such as canopy temperature, ground cover and spectral reflectance. PrometheusWiki protocols complement those describe in this manual, in particular a field-based 'megaprotocol' for experimental plot sampling, handling and processing of cereal experiments (Rebetzke et al. 2012). The editors of PrometheusWiki invite you to visit the site (http://prometheuswiki.publish.csiro.au), search for a protocol CSIRO PUBLISHING


In the present work, we consider the numerical solution of the multipoint nonlocal boundary value problem for elliptic‐parabolic differential equations. A finite difference method for solving the problem is studied. The first and second orders of accuracy difference schemes are presented. The stability, almost coercive stability and coercive stability for the solution of these difference schemes are established. The method is illustrated by numerical examples.


The uptake of 3H‐labeled leucine into proteins, a widely used method for estimating bacterial carbon production (BCP), is suggested to underestimate or overestimate bacterial growth in the open ocean by a factor of 40 uncertainty. Meanwhile, an alternative BCP approach, by the dilution method, has untested concerns about potential overestimation of bacterial growth from dissolved substrates released by filtration. We compared BCPDil and BCPLeu estimates from three cruises across a broad trophic gradient, from offshore oligotrophy to coastal upwelling, in the California Current Ecosystem. Our initial analyses based on midday microscopical estimates of bacterial size and a priori assumptions of conversions relationships revealed a mean two‐fold difference in BCP estimates (BCPDil higher), but no systematic bias between low and high productivity stations. BCPDil and BCPLeu both demonstrated strong relationships with bacteria cell abundance. Reanalysis of results, involving a different cell carbon‐biovolume relationship and informed by forward angle light scatter from flow cytometry as a relative cell size index, demonstrated that BCPDil and BCPLeu are fully compatible, with a 1 : 1 fit for bacteria of 5 fg C cell−1. Based on these results and considering different strengths of the methods, the combined use of 3H‐labeled leucine and dilution techniques provide strong mutually supportive constraints on bacterial biomass and production.


which at that time of year comes at 3.30 a.m. We got away at 4 o'clock. At 7 o'clock that night I was still 10 miles from the Hudson Bay Railway, but that 10 miles was over a muskeg portage, no road, just muskeg, which had thawed out. I set off with three Indians. Never will I forget that night. Every step you sank to your hips, and the only thing holding you up was the ice in the bottom. At last, at 7 in the morning, we walked into the small settlement soaked to the waist. I had been going 27 hours, and was ready to drop. My canoeman flopped in some shack and slept until noon, and then they were to start back, and meet me at the end of the portage sometime that night. I went to the hotel, got cleaned up a bit, and then got on a phone as soon as the telegraph office opened at 8 a.m. I phoned our office in The Pas. As luck had it, a gas car was ready to leave, and come up the railroad the 150 miles. I had him bring all the antitoxin available. I then expressed the throat swabs to Winnipeg, and prepared to await the antitoxin. I could not sleep. Around 5 o'clock, the antitoxin arrived. I had supper, and then hired a horse and guide and set off to meet my canoeman. There was a 17 mile portage, over which I was told I could ride. It was some ride. We had to swim our horses over one river, and jump two creeks. Most of the road was on high ground through the bush, but a lot of it was through swamps. However, we arrived at 4 a.m., just as my boys were getting up. We had breakfast, and then away. I slept a bit in the canoe. I needed it. Finally we arrived back at Cross Lake at 10 p.m. It was just dark. I had been on the road 66 hours with hardly a wink of sleep, and was all in. However; I went to see the cases of diphtheria. As I expected, the one child had died that afternoon. I gave the other child antitoxin and all the others prophylactic doses. There was no more diphtheria, and the one child got better. When I arrived home, there was a wire stating that the throat swabs were positive for diphtheria, and I felt my trip was justified.


There are challenges in anomaly detection and monitoring the data traffic on Internet of Things (IOT) networks which are the results of the state of devices/sensors that's connected to IOT networks. Moreover., protecting and determining the data traffic of devices requires anonymity., another challenge represented by the diversity and heterogeneity of the devices/sensors. Thus., this study proposes a comparison between specific modules which support heterogeneous devices and detect the anomalies data. In this paper., three different ML algorithms (K-Nearest Neighbors., random forest., XGB Classifier) are applied for solving issues related to data traffic management and network monitoring. It is shown that even with the poor data traffic., accuracy between 80% and 89% is achieved for effectively detecting anomality in an IoT network.


Isolated execution environment provides limited resources for running application to application. The application may require access to secure resources associated with a specific confidence level, located on the outside of the isolated execution environment. Trust activation engine operates differently to determine a confidence level associated with the request for the resource based on the trust level. Broker process can be used to run the component that provides access to a resource with a partial trust level in the execution environment separated and isolated execution environment.


The effects of glutamine( Gln) on growth performance,intestinal morphology and non-specific immune related gene expression of juvenile yellow catfish( Pelteobagrus fulvidraco) were evaluated in this study.Tw o hundred and forty juvenile yellow catfish with the initial body weight of( 2. 49 ± 0. 04) g were randomly divided into four groups with three replicates,and there were tw enty fish in each replicate. Four experimental diets were formulated to contain 0( control),0. 10%,0. 20% and 0. 40% Gln,which were randomly fed one of four groups for 70 days. The results show ed that the growth performance indices were not significantly affected by Gln supplementation( P 0. 05). Diets supplemented with Gln could improve the intestinal villus development,and increase the villus height and folds depth,but decrease the muscle thickness. Compared with control group,the intestinal villus height and folds depth in 0. 20% and 0. 40% groups were significantly increased( P 0. 05),and the muscle thickness was significantly decreased( P 0. 05). For the Gln supplemental level at 0. 10% to 0.20%,the mRNA relative expression level of metallothionein( MT) in muscle had the most obvious change,and that in supplementation groups was significantly higher than that in control group( P 0. 05); the mRNA relative expression level of glutathione-S-transferase( G ST) in intestine got the most obvious change,and that in 0. 20%group was significantly higher than that in control group( P 0. 05); the mRNA relative expression levels of heppatic bactericidal protein( Hepc) and heat shock cognate protein 70( Hsc70) both in liver got the most obvious changes,the mRNA relative expression level of Hepc in 0. 10% group was over 73 times than that of control group( P 0. 05),and the mRNA relative expression level of Hsc70 in 0. 20% group was over triple than that of control group( P 0. 05). In summary,these results suggest that Gln can improve the non-specific immune and antioxidant ability of juvenile yellow catfish at certain supplemental level.


Amorphous alloys of the types Zr1-xNix, Zr1-xCox, Zr1-xFex and Zr1-xCux were prepared by melt-spinning and studied by means of differential scanning calorimetry and X-ray diffraction. The crystallisation temperatures (Tx) and the activation energies for crystallisation ( Delta E) were determined. The former values were found to vary only slightly with concentration while the latter show a marked concentration dependence, which is particularly pronounced in Zr1-xNix. The occurrence of compositional short-range ordering (CSRO) in amorphous systems is discussed with respect to its consequences for the hole model proposed earlier. It is shown that the predictions of the hole model are only slightly affected by the occurrence of CSRO, owing to a gross cancellation of the effects of a decreasing hole formation enthalpy and decreasing configuration entropy. The relatively strong temperature dependence of the configurational entropy expected for alloy compositions with strong CSRO leads to an increase in the experimental values of the apparent activation energies. From the concentration dependence of the experimental activation energies indications can be obtained about the concentration dependence of CSRO. It appears that the regions with a maximum CSRO do not, in general, correspond to the concentrations at which intermetallic compounds occur, nor do they correspond in all cases to regions located around the deepest eutectic composition.


We present a new technique for analyzing platforms that ex- ecute potentially malicious code, such as web-browsers, mobile phones, or virtualized infrastructures. Rather than analyzing given code, we ask what code an intruder could create to break a security goal of the plat- form. To avoid searching the innite space of programs that the intruder could come up with (given some initial knowledge) we adapt the lazy intruder technique from protocol verication: the code is initially just a process variable that is getting instantiated in a demand-driven way dur- ing its execution. We also take into account that by communication, the malicious code can learn new information that it can use in subsequent operations, or that we may have several pieces of malicious code that can exchange information if they \meet". To formalize both the platform and the malicious code we use the mobile ambient calculus, since it provides a small, abstract formalism that models the essence of mobile code. We provide a decision procedure for security against arbitrary intruder pro- cesses when the honest processes can only perform a bounded number of steps and without path constraints in communication. We show that this problem is NP-complete.


The field of social choice dates back to the eighteenth century, when Borda and Condorcet started a never-ending discussion about the use of either positional or pairwise information. Three centuries later, after countless axiomatic characterizations of voting rules, impossibility theorems and many other study subjects, researchers still debate whether positional information is really sensitive to manipulation or pairwise information disregards the transitivity of voters' preferences. In a previous paper, we introduced the notions of supercovering relation and pairwise winner, which resulted in a meeting point for both points of view of the theory of social choice. In this paper, we continue this direction and propose the notions of superdominance relation and positional winner that will prove to be the alter egos of the supercovering relation and the pairwise winner when positional information (rather than pairwise information) is considered. Moreover, we analyse a new interesting choice set: the unsuperdominated set.


Overturn could happen if train is subjected to strong wind. Numerical simulations were conducted in order to simulate the flow around train when subjected to cross wind with several overturn angles. Non-linear trend of rolling moment was obtained, and the lateral forces and lift have different impact on the moment. The location of maximum positive pressure and minimum velocity moved from side surface to the bottom surface with overturn angle increased. Flow separation velocity is lower at big overturn angle because of the slant surface.


It is easy to think that tom Andersen's central contribution was the introduction into psychotherapy and family therapy of the "reflecting team" – later to be developed into "reflecting processes." But Tom thought of himself as "a wanderer and worrier" – he was constantly reflecting on his own practice, on his way of 'going on', to further develop and refine it, and then continuing further to worry about the right words in which to express what seemed to be his new way. Each new way came to him as he reached a 'crossroads', a moment when he could no longer continue in the same way, a moment when he stopped doing something he came to see as ethically wrong. In these special moments, he found that "alternatives popped up almost by themselves" (Anderson and Jensen, 2007, p.159) – a special phenomenon in itself, as we shall see. There are thus many, many more features to tom's way of therapy than just his use of the reflecting process. Central to Tom's way of being in the world was what came to him as he moved around in the world, as a participant in it rather than an observer of it. Thus below I will try to set out many of the small detailed changes Tom made in his way-ofbeing-with those around him in his meetings with them, and the large changes these small changes led to. These changes matter to us all. Thus we must do more than merely commemorate his achievements, we must work out how not to forget them, ever. "What we come to form, and thereafter understand (both the formed and the forming), emerge from us being in language in conversations in movements in relationships in culture in nature (we do not have language, etc., in us). The Being in these various ins can best be understood by letting the feeling that comes (by being in these various ins) create its own metaphors, and let those metaphors be part of the language one searches through in order to find a meaning" (Andersen, no date).


ABSTRACT Vegetable oils and animal fats comprise of triglycerides which are formed by fatty acids. Some fatty acids, particularly those having the unsaturated bond are not easy to purify. For this reason, it is not possible to determine exactly the higher heating values (HHVs) of unsaturated fatty acids experimentally via the correct way. HHVs of fatty acids can be determined based on carbon (C), hydrogen (H), and oxygen (O) contents in their chemical formula, experimentally HHVs can be determined relatively easily by using common laboratory equipment. The HHVs (MJ/kg) of the fatty acids as a function of percentages of the C, H, and O can be calculated from: According to this equation, the HHV is a function of the percentages of the C, H, and O of the dry and ash-free basis (daf). This equation represents the correlation obtained by means of regression analysis. It is found that the calculated values show mean difference of 0.30%. The correlation coefficient is 0.9917.


Objective To evaluate the effectiveness of applying simulation based medical education (SBME) in critical care medicine PBL teaching. Methods Totally 46 undergraduates in medical college of Shanghai JiaoTong University , who participated in critical care medicine PBL teaching in our Hospital from 2012 to 2013 were chosen as research objects. These students were divided into two groups: PBL group (2009 grade, n=24) and SBME-PBL group (2010 grade, n=22). The teaching effectiveness was evaluated by questionnaire survey, theoretical exam, direct observation of procedural skills (DOPS) and mini-clinical evaluation exercise (Mini-CEX). Data were analyzed by SPSS 17.0 software. The data of questionnaire survey were expressed as percentage and the assessment results were expressed as x^-±s. Chi-square and t test were used to do statistical analysis. P〈0.05 signifies for statistically significant differences . Results ①The results of questionnaire survey showed that:there was no significant difference between two groups in study interests(P=0.665, 0.937, 0.746) and study ability(P=0.937, 0.665). But regarding collaboration ability, SBME-PBL group performed better than PBL group (P=0.019, 0.038, 0.024). ②These was no significant difference in the theo-retical knowledge exam between PBL and SBME-PBL group(P=0.743). But the DOPS scores of cardiopulmonary resuscitation (P=0.000), endotracheal intubation (P=0.023), defibrillation (P=0.002) and central venous catheterization(P=0.047) were all significantly higher in SBME-PBL group than in PBL group. ③In Mini-CEX, there was no statistical difference in physical examination skills (P=0.790) and clinic judgment(P=0.426) between the two groups. However, SBME-PBL group performed better in medical interviewing capacity(P=0.002), humanistic care (P=0.001), counseling skills(P=0.017), organization efficiency(P=0.029) and overall clinical competence(P=0.024) than PBL group. Conclusions SBME can promote the students' team work spirit, basic clinical skills and comprehensive clinical capacity in critical care medicine PBL teaching and can improve the teaching quality of critical care medicine.

Key words:
Problem-based learning; Simulation based medical education; Critical care medicine; Clinical teaching


Vol. 23, No. 4 ♦ 2005 the doctrine that Maimonides is said to conceal from his public (pp. 43–83). I know of no medieval Jewish philosopher who was seriously disturbed by Divine immutability or who thought that it should be hidden from the multitude. The most difficult issue to resolve in Maimonides' theory of providence is not whether he believed in some sort of individual providence (he clearly does), but how to understand his remark that superior individuals are protected from material ills, albeit only when they have achieved some sort of connection with the Divine. There is also the issue of reconciling the extraordinary speculation of 3.53 with the earlier discussion on providence. On these issues the book is silent, perhaps because they are not accompanied by scriptural prooftexts. Still, no reader who takes Maimonides seriously, especially his claim to have written the work with exceeding precision, will be able to treat his prooftexts the same after reading this book. Whether a given interpretation is convincing or not, the cumulative effect of the book will be to force the reader to take Maimonides' exegesis more seriously than before. In sum, this is a challenging and rewarding book, though it left this reviewer skeptical as to the merit of its fundamental methodology and claims. Charles H. Manekin Department of Philosophy University of Maryland


By analyzing of the principle of motor learning and the competitive ability of athletes in action,the result shows that the form of feedback of motor learning is an important factor that affects the competitive ability of athletes in action.It puts forward the corresponding training methods so as to give substantial reference value for improving competitive ability of athletes in action.


If students acquire a new mathematical notion, according to Sfard (1991), they pass through different phases: an operational and a structural phase. At a grammar school in Bremen, Germany, students of age 12 to 14 first came into contact with the notion of variable using a simple programming language without a computer. As a part of the learning environment the students wrote imaginary dialogues in which they let two protagonists talk about different tasks. The imaginary dialogues of the students are analysed against the background of Sfard's theory of the dual nature of mathematical conception. In particular, the different steps towards a structural conception of the notion of variable in the context of the programming learning environment are elaborated.


A new polymer-supported reagent—poly {[4-hydroxy (tosyloxy)iodo]styrene has good reactivity in the formation of 2-amino-4-arylthiazoles, and the procedure of regeneration and cycle are also described.


Abstract. Three absorption improvement techniques are numerically applied to a multiband metamaterial absorber design for solar energy harvesting. These techniques are the following: the reshaping of the back metallic plate, the integrating of graphene sheets, and the utilizing of indium tin oxide (ITO), in the design. Based on numerical simulation results, each of these methods has the capacity to enhance total absorption rates. In addition to the enhancement in the total absorption rates, new absorption peaks are also obtained within the various frequency regions (infrared and ultraviolet). Furthermore, the absorption enhancement abilities of the mentioned methods are also compared. Among all the techniques, ITO provides the highest absorption rates, as it enhanced the total absorption rate by 48.5%.


In order to bait birds for nesting in Perm in 2003 there were 200 artificial nesting places made in Cherayaevskii Wool, in the Pintry, in Mindovskii Garden and Egoshihinskii Cemetery. The total number of the population was 34%. The hollow for nesting were used by 4 species of bh-ds. Dominatmg species are the big tit (38,2%) and the fly-catcher (54,4% of populated nesting hollows).


22 September 2005 MORE INTERSTATERS COMING TO LIVE HERE The Territory has recorded positive interstate migration for the first time since 1999, Treasurer Syd Stirling said today. Mr Stirling said according to ABS data for the March quarter 2005, the Territory's annual population growth rose to 1.3% higher than national growth of 1.1% and the third highest in the country. This is the seventh consecutive quarterly population increase for the Territory. "Our population increased by 923 people in the quarter, with a total of 201,767 people now living in the Territory," Mr Stirling said. "Net interstate migration increased by 192 in the March quarter – the first increase since the December quarter 1999. "Net overseas migration was also up by 85 people, while the natural increase (births minus deaths) was up 646." Mr Stirling said population growth was in line with the Territory's growing economy. "Prospects in the Territory are bright and people are recognising that and voting with their feet," he said. "This significant improvement in interstate migration reflects the Territory's strengthening economy, particularly in the construction and tourism sectors. "A growing population means more work for local business, more money in the economy and more jobs. "Government will continue its efforts to attract more people to the Territory, particularly skilled labour, to keep the economy moving ahead."


The present paper describes the conceptual design and potential scientific and engineering applications of the Geodynamics Laser Ranging System (GLRS). The latter instrument is a spaceborne laser ranging and altimeter system. It is currently scheduled to be launched in the 1997 time frame as a facility on the first European polar orbiting platform which is being developed as part of the multiple satellite Earth Observing System (Eos). In the geodynamics or retroranging mode, the system will use the green and ultraviolet output from a subnanosecond pulse, frequency-tripled, Nd:YAG laser to measure the geometric range from the spacecraft to arrays of strategically placed groundbased retro-reflectors. The use of two colors, in conjunction with a two picosecond resolution streak tube receiver to measure the interpulse propagation delay introduced by atmospheric dispersion, will permit measurement of the geometric range with an absolute accuracy of 0.5 cms or better. Large radar cross- sections, on the order of a million square meters from the passive ground retroreflectors permit the use of small (0.18 m) receiver telescope diameters and optical trackers with the high slew rates and fast settling times necessary to interrogate large numbers of targets in a typical ten minute pass over the array. This data can be processed to provide decimeter accuracy satellite orbital ephemeris to collocated instruments, perform centimeter accuracy global geodetic measurements, provide data on the motion of tectonic plates or ice floes, and produce high spatial resolution information on regional crustal deformation caused by seismic, volcanic, or other forces such as oil or water withdrawal. Other potential scientific uses include the measurement of atmospheric surface pressure, ocean wave height and surface roughness, cloudtop heights, subnanosecond time transfer between widely separated sites, and longterm general relativity experiments. In the engineering arena, GLRS could provide preliminary surveys in support of land management applications or large scale engineering projects such as interstate highways as well as important information on long term ground stability relevant to the location of nuclear power plants, pipelines, aquaducts, dams, etc. The unconverted fundamental Nd:YAG radiation at 1.06 micrometers is directed to a nadir or near-nadir viewing altimetric channel and viewed by a somewhat larger (0.5 m diameter) telescope. A topographic channel provides both time-of-flight to the underlying terrain and nanosecond resolution waveforms to study geologic structures, transport properties associated with sand dunes and lava flows, and the thickness, growth, and decay of ice sheets. A second lower resolution digitizer provides data on cloud distributions and cloudtop heights.


The performance of aircraft propulsion system is assessed through flight test and its database is published to analyze aircraft performance of full-scale airframe. In this paper, The details of program development to analyze propulsion performance of reciprocating engine aircraft through flight test are described. The development program adopts the key point of development requirement according to importance evaluation of results that user requirements are analyzed by using AHP, and the program"s key quality characteristics are derived through quality function deployment method based on ISO 9126 reference which is software quality model and also, the program"s main function is implemented as a package by using Labview. This program applied to analysis of flight test data of KC-100. And, it is verified that this program is developed properly.


Research has shown that a better understanding of mathematics education in the K-12 classrooms with an emphasis on meeting the needs of students with mathematics difficulties in an inclusive setting is crucial. Unfortunately, there is limited literature available for teachers, parents, and educators to prepare them for teaching mathematics in an inclusion setting. This chapter provides an in-depth discussion on how students' understanding and mathematical thinking, reasoning, and sense directly correlate to achievement in mathematics courses, higher-level academic courses, and in-career opportunities. This chapter provides researchers, scholars, educators, parents, and students an invaluable resource and deeper insight for understanding how effective mathematics instruction can benefit all students in an inclusive classroom.


Objective To establish a pyrosequencing method for detection of AGTR1 A1166 C gene polymorphism,and verify the accuracy of this method study correlation between AGTR1 A1166 C and primary hypertension. Methods The accuracy of the pyrosequencing 192 volunteers are detected by 3 730 type machine provided by ABI company. The genotypes of 100 patients with essential hypertension and 100 healthy persons are detected by pyrosequencing. Results The results of pyrosequencing are consistent with ABI-3730 xl. 1166 C allele frequency(7. 5. %) of EH patients is higher than healthy persons'(6. 0%) without statistical significance(P 0. 05). Conclusion Pyrosequencing is a reliability and convenient method. There is no correlation between AGTR1 A1166 C gene polymorphism and EH.


In this paper, we present a novel spectral factorization algorithm based on linear fractional transformations and the Nevanlinna-Pick interpolation theory. The algorithm is recursive and depends on a choice of points (zk, k=1, 2, ...), inside the unit disk. A mild condition on the distribution of the zk's ensures convergence of the algorithm. The algorithm is quite flexible and convergence can be controlled by the selection of zK's.


We study domain walls interpolating between the physical electroweak vacuum and the global minimum of the Standard Model scalar potential appearing at very high field strengths. Such domain walls could be created in the early Universe under the assumption of validity of the Standard Model up to very high energy scales. The creation of the network of domain walls which ends up in the electroweak vacuum percolating through the Universe is not as difficult to obtain as one may expect, although it requires certain tuning of initial conditions. Our numerical simulations confirm that such domain walls would swiftly decay. Moreover we have found that for the standard cosmology the energy density of gravitational waves emitted from domain walls is too small to be observed in present and planned detectors.


Hepatitis C virus (HCV)‐specific CD8+ T cells in peripheral blood mononuclear cells (PBMCs) from patients infected with HCV were quantitatively analyzed by flow cytometry using an HLA‐B*3501‐HCV epitope tetrameric complex. In chronic hepatitis C, tetramer+CD8+ T cells were detected at frequencies ranging from 0.05% to 0.12% of total CD8+ T cells. The number of tetramer+CD8+ T cells in acute phase PBMCs from patients with acute hepatitis C was about 3 to 5 times higher than in recovery phase PBMCs from the same patients and in PBMCs from patients with chronic hepatitis C. Expanding tetramer+CD8+ T cells in PBMCs from patients with acute hepatitis C express a CD28+CD45RA− memory T‐cell phenotype. In contrast, tetramer+CD8+ T cells in PBMCs from patients with chronic hepatitis C did not predominantly express this phenotype. These tetramer+CD8+ T cells did not have perforin in their cytoplasma. The present study visually showed that a high number of circulating HCV‐specific CD8+ T cells in acute phase PBMCs from patients with acute hepatitis C are mostly memory T cells.


To understand how giving birth during the coronavirus disease 2019 (COVID‐19) pandemic affected women based on birth parameters (gestational age, type of birth and body weight at birth), satisfaction with childbirth, and development of postpartum depression.


Protein-losing enteropathy (PLE) and obstructive jaundice as initial findings of Hodgkin's lymphoma are extremely rare in childhood. The diagnosis of PLE and obstructive cholestasis is critical because early diagnosis and treatment are important for improving survival in patients with Hodgkin's lymphoma.


The lower solar atmosphere consists of partially ionized turbulent plasmas harboring velocity field, magnetic field, and current density fluctuations. The correlations among these small-scale fluctuations give rise to large-scale flows and magnetic fields which decisively affect all transport processes. The three-fluid system consisting of electrons, ions, and neutral particles supports nonideal effects such as the Hall effect and ambipolar diffusion. Here, we study magnetic transport by the laminar- and turbulent-scale ambipolar diffusion processes using a simple model of the magnetic induction equation. Based on a linear analysis of the induction equation, we perform a one-dimensional numerical simulation to study the laminar ambipolar effect on medium-scale magnetic field structures. The nonlinearity of the laminar ambipolar diffusion creates magnetic structures with sharp gradients in the scale of hundreds of kilometers. We expect that these can be amenable to processes such as magnetic reconnection and energy release therefrom for heating and flaring of the solar plasma. Analyzing the characteristic timescales of these processes, we find that the turbulent diffusion timescale is smaller by several orders of magnitude than the laminar diffusion timescale. The effect of the modeled turbulent ambipolar diffusion on the obtained field structures is briefly discussed.


Based on the technology concept and application of IOT, the technology of IOT is applied to the monitoring and safety early warning of bridge health to improve the level and efficiency of the operation and management in safety of bridge. The article discusses the key issues involved in the application, from the selection and optimized layout of sensors, the acquisition and transmission of monitoring data, the architecture and function of the bridge health monitoring system, safety early warning model research of bridge etc. And the article provides scientific basis for decision making in the safe operation and daily maintenance and management of bridges.


In this pilot study, muscle interstitial urea concentrations during hemodialysis (HD) were determined with a microdialysis technique and the results were compared with plasma water urea concentrations. Three patients were investigated during a total of five treatments. Under predialysis steady-state conditions, no difference was observed. During treatment, the muscle interstitial urea concentration was on average 19% higher (range 13–28%, n=4) than the plasma urea concentration after 17±3 min, 29% higher (25–31%, n=3) after 53±10 min, 40% higher (26–50%, n=3) after 117±6 min, 31% higher (26–34%, n= 3) after 179±5 min, and 31% higher (27–36%, n=4) after 231±5 min. The gradient declined after the conclusion of HD, muscle interstitial concentrations being on average 16% (9–26%, n=4) higher than plasma urea concentrations 9±2 min after treatment, and 8% (6–10%, n=3) 25±3 min after treatment. Thus, a urea concentration gradient with a higher concentration in muscle interstitium than in plasma, developed during HD, and dissipated gradually after treatment. This is consistent with blood flow-dependent urea sequestration in muscle tissue, causing intercompartment disequilibrium of urea during HD, and its consequent redistribution after treatment contributing to postdialysis urea rebound.


We previously proposed a bicycle rider behavior visualization method using a probe bicycle equipped with an accurate speed sensor, a rotary encoder to measure handle angle, and a sensor to detect tilt of the bicycle body. However, the probe bicycle is expensive and inhibits wide use of this visualization method. To resolve this problem, we employ a smartphone as the sensor device. This newly proposed method focuses on the azimuth angle because the magnetic sensor is robust to the unwanted effects of bicycle body vibration. A prototype system has been implemented with an Android smartphone-the Sony Corp.'s Xperia. The visualization results generated by the proposed approach are comparable to those of the conventional probe bicycle approach. Using the prototype system, we evaluated the difference between young and aged riders. This experiment statistically clarified a decline in bicycle control for aged riders.


Using micro-unit module analyzed effects of moisture content on testing results of log defects.In order to get defects recognition quality coefficient,tested stress wave traveling velocities in varies moisture content,and studied correlation of stress wave traveling velocities and log moisture content.The results showed that the testing results could be advanced in the light of ways that detected log flaws in lower moisture content.


The invention discloses a remote updating method for information security equipment. The invention uses a distal source equipment which acts as an upgrading side to proceed security treatment to an upgrading information. And the information security equipment which acts as an upgraded side proceeds legitimacy verification to the received upgrading information. Only if the verification pass is the upgrading information used to carry out the upgrade of internal program or data. So the information security equipment is ensured not to use the upgrading information which is distorted or forged by an attacker for the upgrade of internal program or data. So the attacker using an upgrading interface for attacking and destroying the information security equipment is avoided. So the creditability and reliability of remote updating of the information security equipment is guaranteed. At the same time, an upgrading error caused by the upgrading information making a mistake in the process of transmission is avoided. The invention also discloses a remote updating system for information security equipment.