A brief review concludes that there is now good overall agreement between theoretical estimates of the energy associated with the production of the observed metal content of the Universe and the observed extragalactic background light. In addition the overall form of the star-formation history over 0 < z < 5 is reasonably well constrained.
The study of emission line gas in galaxies as a function of redshift provides a complementary view of chemical evolution to that obtained from studies of absorption line systems in quasar spectra. Emission line gas is more relevant for some questions, including the confrontation with models for the chemical evolution of our own and other galaxies, and Origins-related questions about the formation of stars and planets. Using relatively crude diagnostic parameters such as Pagel's R23, the increase of the metallicity of star-forming gas with cosmic epoch can be tracked. Observations of a large sample of CFRS galaxies at z ~ 0.8 (a look-back time of 0.5 t0 show the appearance of a significant number of low metallicity systems amongst luminous L* galaxies. However, overall there is only a modest change in mean metallicity compared with the present, D log Z = -0.08 +- 0.06. These data do not support a fading-dwarf scenario for the ``faint blue galaxies''. At z ~ 3 it is likely that all star-forming galaxies have sub-solar metallicities. The overall increase in the metallicity of star-forming gas with cosmic epoch matches rather well the age-metallicity relation in the solar neighbourhood and some recent models for the evolution of the global metallicity of gas in the Universe.


This project describes the modeling and the control of a distribution static synchronous compensator (DSTATCOM), with the point of enhancing the nature of electric system; we were additionally required to create and actualize a strategy for control by a fuzzylogic controller. Distribution STATCOM (D-STATCOM) is an inverter based power quality conditioner gadget used to enhance the power quality issues in appropriation frameworks. Exchanging beats for the five-level inverter are created by Space Vector Modulation (SVM). Simulation results are given to design the execution of our voltage controller using voltage shunt processing.


Since 1990 The Linde Group has been pioneering the use of oxyfuel heating which is by now common practice in the steel industry. Increased throughput and flexibility, reduced fuel consumption and decreased emissions of CO2 and NOx are the main reasons why the use of oxyfuel-based heating has become increasingly popular. In parallel to the usage of conventional oxyfuel, flameless oxyfuel combustion has proved to offer great advantages. Since 2003, more than 30 furnaces within the steel industry have been equipped with this innovative technology – with outstanding results.


An overview of specializations in the Bachelor of Science- Business & Economic Development degree program at ABAC, as well as academic resources available for the program at ABAC. Databases and journals available through GALILEO for researching business & economics


Numerous studies have considered infections as pairwise interactions between a single pathogen and its host, sometimes leading to an incomplete picture of infectious processes. In this work, we focused on more complex types of interactions that arise because infections are usually heterogeneous. More precisely, we have investigated two main issues: (I) how pathogen transmission is impacted by phenotypic heterogeneity which arises within the pathogen population during the infection, and (ii) how do pathogens interact with the bacterial community which is naturally associated to the host before infection? To assess these questions, we have been studying Xenorhabdus nematophila, an insect-killing bacterial pathogen which is transmitted by a nematode vector, Steinernema carpocapsae. One interesting feature of X. nematophila is that it produces different sub-populations during the course of an infection, each one having distinctive phenotypic features (e.g. one form produces antibiotics and is mobile, while the other does not produce antibiotics nor flagella). In this work, we first tried to identify the molecular mechanisms responsible for this diversification of phenotypes, and tested if phenotypic heterogeneity in X. nematophila has some adaptive value. We showed that some of these phenotypic forms were mutants, which seem to be under strong positive selection during infection. We also showed, however, that these mutants impair nematodes reproduction, which in turn reduces transmission. Therefore, the dynamics of phenotypic heterogeneity in X. nematophila seems to be determined by contradictory short-term and long-term selective pressures. A second interesting feature of X. nematophila is that it produces a lot of antimicrobial compounds which should allow it to dominate the bacterial community inside the insect it has killed. This can be key to ensure the re-association of X. nematophila with its nematode vector inside the insect cadaver. We investigated the bacterial composition of the microbial communities present in insects cadavers after infection by X. nematophila. We found that despite the numerous antibiotics it is able to secrete, X. nematophila is far from dominating microbial community after host death. It rather cohabits with microorganisms from the microbiota of both the insect host and the nematode vector. This raises numerous questions about the impact of these other microorganisms on Xenorhabdus-Steinernema interactions, and therefore on their potential influence on how this mutualistic association has evolved.


PURPOSE
This article reviews the literature on the anatomy and the role of the implant-mucosal interface in the long-term success of oral endosseous implants.

MATERIALS AND METHODS
In vitro, in vivo animal, and in vivo human studies are reviewed and discussed.

RESULTS
The anatomy of the implant-mucosal interface is described. The interface shares many features with periodontal mucosa. A clinically healthy implant-mucosal interface is a routine and predictable occurrence. The validity of using traditional clinical periodontal parameters to indicate or predict changes in peri-implant marginal bone height is unproven, especially if inflamed mucosal tissues are present.

CONCLUSION
In general, the human host response of peri-implant mucosa to long-term functional challenges is favorable.


Abstract : Decision makers do not make choices as unitary actors. This study examines interagency conflicts within the US government's decision-making processes in cases of coercive intervention and the manner in which such conflicts affect policies regarding termination and withdrawal. Specifically, it also examines conflict termination policies regarding the second Persian Gulf War and the Bosnia conflict.


After the Middle of Ming Dynasty, traditional ethic and social ranks and were loose for changes of social and economic background. Some social problems, therefore, appeared, like dissipated, litigious, swindles, more and more unemployments, and more the gangs of rascals emerged. The gangs that composed by rascals or ruffians, emerged for a very important purpose, profits. In order to procure more and more filthy lucre, all villanies they would do to their vicinages; and there were not any ethic or doctrine could embarrass them, so these evil gangs were not similar to the secret societies. Because they would do any thing benefit to themselves, there were various styles of evildoing. A tough guy would be a muscleman to fight for his boss, this kind of gangs called "Ta-Haang" (gang for fignt); some made threats by bringing in lawsuit against victims for procuring money, called "Pa-Kung"; and some others racketeered by rumors and imputations, they were called "Wuo-Fang". The subject of this study, Wuo-Fang, was a kind of gangs who racketeered or revenged victims by rumoring and imputing while the Royal Censors (a kind of itinerants) coming to check and preside local governments. I shall examine the background, victims, parterners, and influences of Wuo-Fang in this study, for the purpose to understand the life of mobs of ancient China.


Abstract In this work, we study the endomorphism set of quasi-injective gamma acts, by defining some concepts like J(M), T(M) for any S Γ -act M, and the important result we predict the regularity properties' of endomorphism set under some conditions and we study a set where x is an element of M we give description of in terms of the endomorphism α – monoid of quasi-injective gamma acts.


The serine and threonine kinase AKT (also known as protein kinase B, PKB) integrates inputs from growth factors and metabolic effectors to control key multifunctional signaling hubs via direct phosphorylation of substrates that control cell growth, proliferation and survival. Among critical pro-survival mechanisms, autophagy is an evolutionarily conserved housekeeping pathway that functions to degrade and recycle macromolecules and organelles as part of basal cell metabolism as well as in response to specific stimuli. Autophagic degradation is based on the activity of the lysosome, a membrane-enclosed organelle that contains a wide array of hydrolytic enzymes with different macromolecule specificities. Our previous work has established that transcription factor EB (TFEB) acts as a master regulator of the autophagy-lysosome pathway (reviewed in ref. 3). Since the initial characterization of TFEB as a transcriptional modulator of the lysosomal system, cytoplasm-to-nucleus translocation of TFEB has been identified as the main mechanism underlying regulation of TFEB activity. While several proof-of-concept studies have shown that exogenous expression of TFEB can counteract appearance and progression of pathological changes in animal models of diseases with a prominent intracellular storage component, clinical translation has been limited by the lack of suitable entry points to modulate TFEB activity that are amenable to pharmacological manipulation with available drugs. Our recent work has uncovered AKT-mediated phosphorylation of TFEB as a mechanism by which AKT modulates the autophagy-lysosomal pathway. AKT phosphorylates TFEB on serine 467, a residue that is evolutionarily conserved in vertebrate species and that is also conserved in TFEB's close homologs, TFE3 and MITF. A TFEB phosphomutant in which the AKT phosphoacceptor site was substituted by alanine to impede AKT-mediated phosphorylation (TFEB S467A) showed increased nuclear localization and stability as well as increased ability to activate TFEB downstream target genes, thus indicating that TFEB function is inhibited by AKT phosphorylation. Accordingly, both AKT knockdown and pharmacological inhibition of AKT promoted TFEB nuclear translocation; AKT inhibition also activated TFE3 and MITF, thus revealing conservation of this regulatory pathway (Fig. 1). Notably, AKT inhibition resulted in increased number of LC3-positive autophagic vesicles and increased expression of autophagic and lysosomal genes, thereby indicating global enhancement of the autophagy-lysosome pathway. Similar results were obtained with trehalose, a natural disaccharide that stimulates autophagy and exerts neuroprotection in various models of neurodegenerative proteinopathies. The mechanism of action of trehalose has been elusive for more than a decade; recent work has shown that trehalose inhibits the activity of glucose transporters at the plasma membrane, thus inducing a starvation-like state that promotes autophagy via the AMPK-ULK1 axis. We have shown that trehalose inhibits AKT activity in vitro and in vivo, thus resulting in TFEB nuclear translocation and activation of the autophagy-lysosome pathway. Importantly, expression of a constitutive active form of AKT prevented trehalose from inducing TFEB nuclear translocation, demonstrating that trehalose indeed activates TFEB via AKT inhibition. Activation of the autophagy-lysosome pathway obtained by pharmacological inhibition of AKT or trehalose administration resulted in enhanced clearance of aberrant proteolipid aggregates in cells from patients with neuronal ceroid lipofuscinosis, a genetically diverse subgroup of the lysosomal storage diseases. Significantly, oral administration of trehalose to a mouse model of juvenile neuronal ceroid lipofuscinosis (Batten disease) diminished AKT activity and promoted TFEB activity in the brain, again resulting in the activation of the autophagy-lysosome pathway and the subsequent clearance of ceroid lipopigments in neurons, which finally led to protection from neurodegeneration and elongation of the life span of affected mice. These findings provide a direct, pharmacologically actionable entry point to modulate TFEB activity and enhance the autophagy-lysosome pathway through increased TFEB function. The AKT-TFEB signaling pathway might be leveraged to devise treatments of degenerative diseases in which there is pathological storage of aberrant aggregates of proteins or other macromolecules, such as in Alzheimer disease, Parkinson disease, Huntington's disease and lysosomal storage disorders. Clinical development of trehalose is currently focusing on the treatment of arterial aging (ClinicalTrial.gov ID:


The study investigated the usage of the F-Word among high school students. It also studied the various factors influencing them to use the word. The sample consisted of 200 students-100 boys and 100 girls, of 10th grade from different schools in North and South Bangalore. The participants provided their demographic details and completed the F-Word Survey Questionnaire. Descriptive statistics were performed to analyze the data. The results suggest that, on an average, 73.5% of 10 th grade students have reported to use the F-Word. The percentage of boys is more than the girls, with respect to the usage of the F-Word. The reasons for using the F-word, in the ascending order of most no. of responses, were- anger/frustration, difficulty in using a decent word instead of the F-Word, peer influence, movie/TV/music influence, the feeling of "grown up", fun factor, trend factor, to abuse, and parental/family influence. Girls use the F-Word more due to anger or frustration, difficulty in using a decent word to express their thoughts, the feeling of "grown up" and parental or family influence, than boys. Also, boys are more influenced by peers, movie/TV/music, fun and trend factors and use the F-Word to abuse, than girls. It was also found that students use the F-Word more in Texting (SMS) than on social networking sites, email and chat rooms. The results also suggest that, on an average, 27.89% of students have reported that their parents are aware of their children using the F-Word. And, 55.88% of students have reported that the F-word usage is inappropriate of their age. On an average, 26.5% of students do not use the F-Word. The percentage of girls who do not use the F-Word is higher than the boys.


. Three weaning diets, with identical nutrient composition but different water content (0%, 30% and 50%), were fed to two size groups of juvenile Atlantic cod, Gadus morhua L., averaging 108 and 16mg respectively. Survival was above 90% after 3 weeks among the large cod and about 40% among the small cod, and was not affected by dietary water content. Specific growth rates (about 8% per day), however, increased with increasing dietary water content among the large size group, but no significant differences could be demonstrated among the small fish. Ingestion rates, estimated by feeding 14C labelled diets, were low among the smaller size group and this probably was the main reason for their low survival. The large size group on the other hand easily accepted the weaning diets.


Steered molecular dynamics simulations of ligand dissociation from Thyroid hormone receptors indicate that dissociation is favored via rearrangements in a mobile part of the LBD comprising H3, the loop between H1 and H2, and nearby beta-sheets, contrary to current models in which the H12 is mostly involved. Dissociation is facilitated in this path by the interaction of the hydrophilic part of the ligand with external water molecules, suggesting strategies to enhance ligand binding affinity.


With the increasing application of energy storage technology in power grid, the traditional chemical energy storage technologies such as kinds of batteries have exposed the problems of low capacity, high cost and short service life. Compressed air energy storage system (CAES) provides a promising large-scale and low-cost energy storage solution. In this paper, the key technologies of compressed air energy storage system are analyzed, and an new economic model is established, which takes into account the life cycle cost, direct income and potential income, to analyze the economic efficiency of compressed air energy storage system. At the same time, a control model of compressed air energy storage system based on filter is proposed and the simulation proves that it is effective in the application of stabilizing wind farm power output fluctuation. The research in this paper can provide a reference for the pricing and operation of compressed air energy storage system in power grid.


This report describes work on the successful completion of Milestone M2FT-14OR03100115 (8/20/2014) entitled, "Complete new adsorbent materials for marine testing to demonstrate 4.5 g-U/kg adsorbent". This effort is part of the Seawater Uranium Recovery Program, sponsored by the U.S. Department of Energy, Office of Nuclear Energy, and involved the development of new adsorbent materials at the Oak Ridge National Laboratory (ORNL) and marine testing at the Pacific Northwest National Laboratory (PNNL). ORNL has recently developed two new families of fiber adsorbents that have demonstrated uranium adsorption capacities greater than 4.5 g-U/kg adsorbent after marine testing at PNNL. One adsorbent was synthesized by radiation-induced graft polymerization of itaconic acid and acrylonitrile onto high surface area polyethylene fibers followed by amidoximation and base conditioning. This fiber showed a capacity of 4.6 g-U/kg adsorbent in marine testing at PNNL. The second adsorbent was prepared by atom-transfer radical polymerization of t-butyl acrylate and acrylonitrile onto halide-functionalized round fibers followed by amidoximation and base hydrolysis. This fiber demonstrated uranium adsorption capacity of 5.4 g-U/kg adsorbent in marine testing at PNNL.


The general purpose of this research was to understand the actual uses of the social network called Google Plus, in a teaching-learning experience at the University level. The research was developed on an online environment. This is an interpretive research, based on a simple case study in which a didactic unit-based experience is planned, developed, monitored, and analyzed quantitatively. The case is carried out in a virtual environment for around one month and with the support of some applications Google Plus provides to its users. The results were analyzed in three moments: In the first stage, planned uses are identified and described; in the second stage, implemented uses are identified and explained; finally, both are contrasted to determine the actual uses for Google Plus in this learning experience. This project received methodological support from a category-based matrix which consisted of the present interactions in the didactic triangle composed by teacher, students, contents, and ICTs as a mediating tool. During the process, these uses were identified: planned and executed; planned and unexecuted; and planned and executed. The uses established the existing relationships between what the teacher prepares and what is carried out. Findings show that, regarding the planning and execution of this experience, Google Plus was used mainly with communicative purposes between the teacher and the student. However, during execution, such interactions emerged in other spaces which had not been strongly considered during planning. Finally, it is concluded that in order to move forward in the possibilities Google Plus offers, it is imperative that these spaces be explored, structuring educational proposals that are developed through them, using the existing applications with pedagogic and didactic purposes.


A fast and accurate analytical method of the new instrument for analysis on the multi-elements of slag can be established by melting samples of the furnace slag into glass wafer using borate as the mixed fusion reagent under the high temperature since the severe mineral congregation effect existing in various furnace slogs can be effectively eliminated and the absorption and build-up effect between elements of the slag can be reduced by adoption of the X ray fluorescent spectrum method in the process of analysis on various elements of the slag.


We argue that culture is an endogenous force of economic development. As such, it should be integrated into the framework of analysis of the dynamics, mechanisms and processes that lead to sustainable development. This shift in contemporary development thought is not random, since the concept of culture has acquired a new dynamism. Development and culture strengthen one another, but also one is a prerequisite for the other. This paper aims at illustrating the need for a composite analysis framework related to the impact of culture on sustainable development, based on dynamics, mechanisms and processes defining the relations between economics and politics, state and market along with values, ideas, principles, perceptions and local culture.


Vehicle activated signs (VAS) display a warning message when drivers exceed a particular threshold. VAS are often installed on local roads to display a warning message depending on the speed of the ...


Eggs of Echinostoma macrorchis were laid at the 1-cell stage and took 9 days (26-27 C) or 6 days (30 C) to hatch. The following accounts are based on studies undertaken at 24-26 C. Maximum survival of miracidia was 7 hr. Miracidia reached the ventricle of Gyraulus chinensis 15-20 hr after penetration and transformed into sporocysts. The earliest degeneration of sporocysts occurred 20 days postinfection (DPI), but some survived for 120 days. Mature mother rediae were first seen inside the sporocyst at 7 DPI, then were released to the ventricular cavity and migrated to other anatomical locations of the host. Among the germ balls present in a sporocyst, 1-3 developed concurrently to the mother redia stage. Young daughter rediae first appeared at 15 DPI and mature ones at 19 DPI. Snails of larger size produced more daughter rediae and cercariae than smaller ones. Initial shedding of cercariae from infected snails occurred between 25 and 48 DPI, with a mean of 34 DPI. The cercariae were phototactic and each snail shed a daily average of 34 cercariae. Gyraulus chinensis was proven to be the only snail capable of serving as the first intermediate host. Tadpoles of Rana latouchi and Bufo bufo, 9 species of gastropods, the bivalve Corbicula fluminea, and I unidentified planarian species served as experimental second intermediate hosts. Echinostoma macrorchis from Taiwan differed from those of Japan in several respects: metacercariae of the Taiwanese parasite were smaller but were already infective 12 hr after encystment, and they matured into adults in 7 days in rats, whereas metacercariae of the Japanese parasite were larger, requiring 35 hr to become infective after encystment, and took 13 days to grow into adults.


Fatigue crack propagation behavior in cold-rolled polycarbonate was studied under constant-amplitude loading and single peak overloading conditions. The results obtained in this experiment are summarized as follows:(1) Cold-rolling improves the resistance of fatigue crack propagation at low ΔK levels in polycarbonate, and restrains the formation of discontinuous growth bands which are easily formed at low ΔK levels in unrolled polycarbonate.(2) The acceleration factor of crack propagation due to a single peak overload is markedly lower in cold-rolled specimens than that in unrolled ones, and the fracture surface of acceleration region shows many fine tearing lines in cold-rolled ones in contrast to the granular markings in unrolled ones. This fact suggests that the cold-rolling restrains the craze formation at the crack tip, which causes lower acceleration.(3) Fatigue crack propagation after a single peak overload shows the so-called delayed retardation in cold-rolled specimens, which contrasts with an undelayed retardation in unrolled ones.(4) The maximum retardation rate after a single peak overload is lower in cold-rolled specimens than that in unrolled ones. This is considered to be due to the smaller scale of the overload-induced crack tip blunting or orientation hardening near the crack tip in cold-rolled ones.


Flexible Manufacturing System (FMS) is a complex asynchronous concurrent system. The model of FMS should have the abilities to express the concurrency in the system and to analyze the behavior of the system. It is difficult to use any one method to model such a complex system as FMS. A modeling and verifying method using object-oriented modeling language "Unified Modeling Language (UML)" and SPIN (PROMELA model) is presented in this paper. Class diagram in UML is used to represent the static relations among the objects in FMS, and state diagram is used to describe the dynamic behaviour of the system. Then the UML model is translated into PROMELA model automatically, and property checking is followed with SPIN which is a model checking tools. The method can describe and check the properties of the system (from modeling, simulation, to model checking), and can be used to design reliable FMS control software naturally.


Temperature dependence of magnetic properties in [Co/Pd]N multilayer have been systematically studied for lithographically patterned samples with different Co thicknesses tCo and the bi-layer number N by extraordinary Hall effect measurements. The perpendicular coercive field Hc decreases with the increase of tCo, excepting a very thin thickness of 1 A. While a threshold temperature (Tth) of Hc vanishing linearly increases with the increase of tCo. The Hc and Tth monotonously increases with the increase of N, ranged from 5 to 50. The superior crystalline structure for samples with the larger N was confirmed from enhanced Co/Pd(111) peak height in the XRD pattern. A practical thermal activation coefficient α of 174 was evaluated from a sweep rate dependence of Hc. A marked improvements for the heat assisted MRAM application was attained by air annealing of [Co(1.7 A)Pd(8 A )]30 at 220 °C, that is, the Hc was increased from 1.3 kOe to 2.9 kOe, while Tth reduced from 210 °C to 190 °C.


A broadband arbitrary polarization antenna system for ground penetrating radar applications is modified to improve its performance. The antenna system uses four, crossed, resistive-vee dipole (RVD) antennas operating bistaticly to measure the simultaneous transmission and reception of multiple polarizations. The RVD has low self clutter, low radar cross section and wideband performance. The RVD is a linearly polarized antenna, but other polarizations can be synthesized through the use of two orthogonal RVDs to transmit or receive orthogonal field components. The antenna system is able to distinguish rotationally symmetric and linear targets with its ability to transmit and receive both senses of circular polarization. For example, linear targets such as wires or pipes can be identified by even scattering of both senses of circular polarization. The RVDs in the previous RVD-based CP (circularly polarized) antenna were not designed for CP synthesis. The shape and resistive profile of the RVD were modified to improve dual CP performance. The design of the RVD was optimized through simulation to improve CP synthesis and forward gain, while maintaining low self clutter, low radar cross section, and wide bandwidth. Additional simulations demonstrate that the improvements to the RVD may help to correctly discriminate targets based on their geometries.


Objective: The purpose of is to investigate the effectiveness of rebound therapy on improving perceptual-visual coordination and social development of students with learning disabilities. Method: This is an applied research. To do this, the semi-experimental method was used using pre-test and post-test with the control group. The population was all the students with a diagnosis of learning disabilities who received the necessary interventions at Dezful Education and Rehabilitation Center for Learning Disorders. The sample included 30 students with learning disabilities in Dezful . They were selected from the above-mentioned center and randomly divided into experimental and control groups (each group consisting of 15 subjects). To collect data, the Visual Critical Scale of the Gastalt and the Social Development of Thailand was used. The experimental group received rehabilitation training for 8 weeks but control group did not receive any intervention. Findings: The results covariance analysis (MANCOVA) showed that rehabilitation training has an impact on perceptual visual coordination and social development and can increase visual-perceptual coordination and social development in students with learning disabilities. Conclusion: These results have some important implication for treatment of learning disabilities, so this educational program can be used as an interventional method at schools and rehabilitation


The following list of French doctoral dissertations is an update on the list printed in the Bulletin (Vol. X, No. 7, February, 1976). The present listing excludes Doctorat de specialite (3eme cycle) and does not include all dissertations submitted in 1976. My thanks again to Madame Helene Faure and Miss Florence Thion at the Fichier Central des Theses, Universite de Paris X-Nanterre, 200 avenue de la Republique, 92000 Nanterre, for their agreeable and friendly cooperation in the preparation of materials. As in the previous bibliography the information provided is author, date of thesis submission and name of university.


The ever-increasing demands of current wireless devices for high data throughput and frequent mobility forces network operators to provide seamless connectivity with guaranteed QoS to all wireless users. This situation creates a big concern in design and development of cost-effective and energy efficient solution for 5G cellular networks. small cells (Femtocells) deployment provides low cost and energy efficient solution if equipped with smart and efficient power saving techniques. In this paper, we have proposed a data traffic demands aware approach for optimum throughput and maximum energy utilization while maintaining the desired QoS required by users. The results and analysis confirm that the proposed approach will not only provide better energy utilization and optimum data throughput but will also contribute towards energy efficient aspect of 5G cellular networks.


Protecting an organization's intellectual property (IP) in the US and Western Europe is relatively straightforward because laws and enforcement mechanisms are reasonably well developed. However, other parts of the world pose significant challenges in safeguarding IP assets due to relatively weak laws and enforcement. This paper examines ways in which multinational enterprises (MNE) can secure knowledge assets across global operations. A comparative company analysis is conducted using a resource based view of the firm. The resulting best practice recommendations could be beneficial for enterprises working in global settings.


Material collected in a field trial conducted in Dark Red Latosol (Typic Euthror-thox) was used to study dry matter and macronutrients accumulation in two cassava cultivars (Branca-de-santa-catarina and IAC-Mantiqueira). Plants received a uniform fertilization of N, P205 and K2O of 40, 80 and 60 kg/ha, respectively as ammonium sulfate, simples superphosphate, and muriate of potash; N was top dressed 60 days after the sprouting. Samples were taken at six occasions during the growing season, with an interval of sixty days between each sampling. The plants were divided into roots, leaves and stems and each part was analysed for N, P, K, Ca, Mg and S. The results showed that: a) The period of greatest dry matter accumulation was between 120 and 180 days after the sprouting of the plants, with the average of 105.0 kg.ha-1.day-1; b) Extraction of macronutrients was the same in the two cultivars, with the exception of P; export was different only in the case of K and S; c) The extraction, in kg/ha and kilograms needed for the production of one metric ton of roots were respectively 113.3 and 6.21 for N, 11.0 and 0.62 for P, 78.6 and 4.24 for K, 62.0 and 3.37 for Ca, 18.5 and 1.00 for Mg and 8.3 and 0.46 for S; d) The export, in kg/ha and kg/ton of roots were respectively 39.1 and 2.12 for N, 3.9 and 0.22 for P, 32.5 and 1.71 for K, 12.1 and 0.66 for Ca. 6.7 and 0.36 for Mg and 1.7 and 0.09 for S.


It is widely acknowledged that Kant's work presents an argument against modern skepticism (see Guyer 2008). However, it is less clear what this argument turns out to be and why, after Kant, skepticism blooms again (see Franks 2014). I argue that for Kant, skepticism is a certain disappointment of the human with its own intelligible powers, being torn between the actual and the ideal. Hence, his response to skepticism implies a limitation of knowledge as well as his image of the human as being of two worlds. The overcoming of skepticism implies the recovery of its voice as intelligible being in following the moral law, a constitution he calls autonomy. However, the image of two worlds, the sensual and the ideal, continues skepticism's most prominent image of two disparate realms (mind vs. body). After Kant, romanticism transforms Kant's two realms into the idea of the transformability of the human in a process they call Bildung (education). Evoking the literal project of "building" according to an image (Bild) or ideal, romanticism imagines a recovery from skepticism as the "up-building" of man out of fragmentation as aesthetic-educational task; a secularized salvific history by replacing God through man as author of one's existence.


Recently, there has been an increase in the desire to use saturated lightweight aggregates (LWA) to reduce shrinkage and shrinkage cracking in low w/c concrete. The use of saturated LWA as a method to provide internal curing involves the partial replacement of normal weight aggregate with saturated LWA. The saturated LWA provides additional water that can replenish the paste to compensate for the effects of self-desiccation. This paper uses Pickett's model to determine the shrinkage of the cement paste portion of a mortar containing different volumes of saturated LWA. The results of the study indicate that while the inclusion of saturated LWA reduces the stiffness of the mortar, the reduction in shrinkage of the paste due to the supply of additional water is more crucial in reducing the overall shrinkage of the mortar. The size of the pores emptied due to self-desiccation is calculated using results from internal relative humidity measurements and are compared with mercury intrusion porosimetry test data. Similar pore sizes are observed with both methods.


An emergency stop device for an elevator is provided to a vertically movable body guided by a guide rail. The emergency stop device has a first emergency stop mechanism and a second emergency stop mechanism which is disposed below the first emergency stop mechanism. The first emergency stop mechanism has first braking bodies capable of being brought into contact with and separated from the guide rail and applies a braking force to the vertically movable body by bringing the first braking bodies into contact with the guide rail. The second emergency stop mechanism has second braking bodies capable of being brought into contact with and separated from the guide rail and applies a braking force to the vertically movable body by bringing the second braking bodies into contact with the guide rail. The position on the guide rail at which the first braking bodies are brought into contact with the guide rail and the position on the guide rail at which the second braking bodies are brought into contact with the guide rail are displaced from each other in the horizontal direction.


Background: Most studies investigating the association between parental occupational pesticide exposure and childhood acute lymphoblastic leukemia (ALL) have relied on job titles. Methods: Children...


This book constitutes the thoroughly refereed proceedings of eight international workshops held in Gdask, Poland, in conjunction with the 24th International Conference on Advanced Information Systems Engineering, CAiSE 2012, in June 2012. The 35 full and 17 short revised papers were carefully selected from 104 submissions. The eight workshops were Agility of Enterprise Systems (AgilES), Business/IT Alignment and Interoperability (BUSITAL), Enterprise and Organizational Modeling and Simulation (EOMAS), Governance, Risk and Compliance (GRCIS), Human-Centric Process-Aware Information Systems (HC-PAIS), System and Software Architectures (IWSSA), Ontology, Models, Conceptualization and Epistemology in Social, Artificial and Natural Systems (ONTOSE), and Information Systems Security Engineering (WISSE).


Abstract Amphetamine, caffeine, and high ambient temperature (125.6 F) were compared with placebo to determine their effects on a variety of strength, psychomotor, and mental performance tasks and certain physiological measures of 24 young men who were students at the University of North Carolina. Performance was measured objectively only after each subject had been given standard extensive practice and acclimatization. The study permitted the conclusions that (a) 15 mg. of d-amphetamine sulfate significantly improved performance but caused a significant increase in heart rate, (b) 500 mg. of citrated caffeine did not produce a significant change in either the performance tasks or the physiological parameters measured, and (c) high ambient temperature (125.6 F) produced a significant improvement in performance.


Mature microRNA (miRNA) is a modulator in the post‐transcriptional regulation. The present study aimed 1) to profile the aldosterone‐regulated miRNAs in mouse cortical collecting duct cells (mpkCCDc14 cells); 2) to identify the main signaling pathways where putative target genes of identified miRNAs are enriched; and 3) to determine the roles of selected miRNAs and target genes in aldosterone‐mediated action.


Objective: We describe how to assess the degree of canal curvature and manage a separated instrument using an ultrasonic device. Case Report: A 24-year-old female was referred by a general dentist for an accidentally separated Protaper F2 instrument. The mesiobuccal canal was enlarged and the separated instrument could be visualized via the dental operating microscope. Preoperative radiography revealed a separated endodontic instrument at the middle to apical third of the mesiobuccal canal. Mesiobuccal canal curvature measured 66°. After rubber dam isolation, a specific ultrasonic tip and the dental operating microscope were used to gain access around the separated instrument until it loosened. The separated instrument was agitated and accidentally sucked into the high-speed suction device. The canal was evaluated with higher magnification via the dental operating microscope and postoperative radiographs were taken to confirm removal. Conclusion: Retrieval of a separated instrument in the curved canal is effective using a specific ultrasonic device plus a dental operating microscope


SYCHOANALYSIS, as a body of scientific knowledge, has developed within the clinical tradition, using the naturalistic approach. P That has proved extraordinarily fruitful. It has led to the accumulation of enormous mass of information, and to a luxuriance of concepts which have illuminated our understanding of psychological processes. Also, it has provided vision into the interaction of psychological with bodily functions and has made a basic, probably the most basic, contribution to the field known as psychosomatic medicine. Rapid growth is seldom smooth or free from growing pains. Psychoanalysis and psychosomatic medicine have had these. The profusion of insights from these disciplines has often been bewildering and at times has seemed to lack scientific rigor. Increasing efforts are being made to test psychoanalytic propositions under controlled conditions and by experiment (13). Experimental methods permit a gain in precision. Unfortunately their inevitable simplification of the field of inquiry may lead to a loss-of the complete, detailed information, which still is so often necessary if we are to explain human behavior. An alternative method for clarifying and testing hypotheses


It is necessary to predict dam inflow in advance for flood prevention and stable dam operations. Although predictive models using deep learning are increasingly studied, these existing studies have merely applied the models or adapted the model structure. In this study, data preprocessing and machine learning algorithms were improved to increase the accuracy of the predictive model. Data preprocessing was divided into two types: The learning method, which distinguishes between peak and off seasons, and the data normalization method. To search for a global solution, the model algorithm was improved by adding a random search algorithm to the gradient descent of the Multi-Layer Perceptron (MLP) method. This revised model was applied to the Soyang Dam Basin in South Korea, and deep learning-based discharge prediction was performed using historical data from 2004 to 2021. Data preprocessing improved the accuracy by up to 61.5%, and the revised model improved the accuracy by up to 40.3%. With the improved algorithm, the accuracy of dam inflow predictions increased to 89.4%. Based on these results, stable dam operation is possible through more accurate inflow predictions.


Block 1 and 2 Combined Cycle Power Plant (CCPP) Muara Tawar have 5 units gas turbine can be operated by using fuel gas. Due to limitation of fuel gas from gas company. Several gas turbine are operated using High Speed Diesel fuel (HSD) to fulfil load demand. The equipment that used for fuel gas system must have high realibility to serve in dual fuel system neither operated using fuel oil or gas without unit trip. In actual, there are several disturbances occur during change over from gas to oil, even when the plant operated using fuel oil. From the data of failure causes, one of the failure causes is valve failure. By considering the availbility of plant, in term of possibility to modify instrumentation and control system, gas turbine 1.3 was choosen as object of the study. Additional indicator in HMI can be described as follows additional pressure switch attribute at EDS-P3 using symbol K, upload program to EPROM at card 70BK06 as communication card, and the cycle time less than 1 second in both valve open or close. It indicate valve system under good condition or no maintenance action is required. Valve maintenance at gas turbine ALSTOM 13E2 in Block 1 and 2 CCPP Muara Tawar can be done by additional indicator of pressure switch and aux relay contact as feedback signal on POS 30. Therefore, no disturbances in valve system and gas turbine performance increases.


The discharge of a preterm infant from neonatal intensive care is a developmental milestone, yet it also marks the beginning of a challenging course of medical care from a complex system of outpatient providers. This article addresses the multiple strategies and resources that exist to help pediatricians coordinate health care and optimize quality of life for these children and their families


This article seeks to determine some of the peculiarities of the economic growth in the countries from the Economic Community of West African States (ECOWAS). Thus, the study is based on the country approach and uses econometric regression tests. In fact, in the context of the determination of the real GDP per capita growth rate of the countries in this region during the period 1987-2014, the results obtained show that it is still weak and unstable. Moreover, the weak convergence that has only been observed beginning with 2008 feeds the hope that ECOWAS can truly improve its level of development despite the heterogeneous nature of the countries. In order to overcome these difficulties, improving the socio-economic performance through the growth rate of real GDP per capita represents, among others, a necessity in relation to economic policy decisions.


With the methods of literature,questionnaire,interview and mathematical statistics,the personnel's quantity condition,the educational background construction,budget source,economic entity's establishment and management relation were compared and analyzed between provincial and national athletics associations in order to find out the differences and similarities.


The focus of this paper is coded orthogonal frequency division multiplexing (OFDM) system for high-speed railway wireless communication based on block Markov superposition transmission (BMST). The effect of Doppler spreading destroys the orthogonality among subcarriers, resulting in intercarrier interference (ICI) in the OFDM systems. In order to mitigate the ICI and get the soft information easily, we present a simple soft output algorithm based on zero forcing (ZF) equalization, and the soft information is given to the soft-in soft-out (SISO) demapper. We combine the OFDM system with BMST code, which can be easily designed for any given code rate with a predictable performance lower bound. Based on the iterative sliding-window decoding algorithm, BMST scheme outperforms the convolutional code (CC) scheme in the OFDM system for quadrature phase-shift keying (QPSK) and 16-quadrature amplitude modulation (QAM). Numerical results show that the BMST-OFDM system performs well over doubly selective channels.


Any public institution aims at properly recognizing and realizing people's claims in society. And one of the main tasks of normative theories of public institution lies in articulating public morality, which includes the principles and forms of the proper treatment of those claims. In articulating this public morality, we have to beware the fact of reasonable pluralism in modern society. 2 People have various claims and related interests in their thinkings and doings which may be complex and conflicting. If this diversity is inevitable, public institution and its normative theory also have to be responsive to it. However, to establish this moral sensibility is not easy. One typical example in this respect is welfare aid. Each individual has her own physiological and psychological conditions: when she has some kind of disease or handicap, the


Abstract This paper proposes an extended Petri net formalism as a suitable language for composing optimal scheduling problems of industrial production processes with real and binary decision variables. The proposed approach is modular and scalable, as the overall process dynamics and constraints can be collected by parsing of all atomic elements of the net graph. To conclude, we demonstrate the use of this framework for modeling the moulding sand preparation process of a real foundry plant.


The adsorption and decomposition of monomethylamine on Ru(001) have been studied using high-resolution electron energy loss spectroscopy and thermal desorption mass spectrometry. Molecular adsorption of CH 3 NH 2 occurs via lone pair donation of the nitrogen atom, and the desorption of reversibly adsorbed methylamine from a saturated first layer is observed over the temperature range 200-340 K. Thermal decomposition of irreversibly adsorbed methylamine (0 CH3NH2 =0.15±0.01 monolayer) produces H 2 , N 2 , NH 3 , and surface carbon adatoms


The effects of feeding frequency on growth performance, feed conversion ratio and survival of post-larvae Indian white shrimp, Penaeus indicus were evaluated in a 56-day study. The study was conducted in sixteen fiberglass tanks provided with aerated recirculating water with four replicate tanks for each treatment. Twenty post larvae with a mean weight of 1.56 0.02g were hand-counted and stocked into each of the replicate tanks and fed 2, 4, 6 and 8 times a day, respectively. Final body weights were measured significantly lower at 2 and 4 times/day (5.76 0.08 and 5.96±0.15g, respectively) than 6 and 8 times/day (8.54±0.16 and 8.31 0.19g, respectively) treatments (P<0.05). There were significant differences for the Feed Conversion Ratio (FCR) of shrimps fed 6 and 8 times/day with other treatments. The best mean FCR was obtained from the sixth daily-feeding (P<0.05). The Specific Growth Rate (SGR) of shrimps fed 6 times/ day was significantly (P<0.05) higher (3.03 0.04%) than shrimps fed with all other feeding regimes, while shrimps fed 8 times/ day had a higher SGR (2.95 0.05%) than shrimps fed 2 times/day (2.36 0.06%) and 4 times/day (2.39 0.11%). Survival rate was significantly different (P<0.05). The best mean survival rate was obtained from 6 times/day feeding (P<0.05). There were significant differences for survival rates (P<0.05). The water quality parameters (salinity, dissolved oxygen and temperature) were not different among treatments. However, some water quality parameters (ammonium, nitrate, nitrite, phosphate and pH) were significantly different among the treatments. Results suggested that there was an advantage in feeding P. indicus more frequently than 4 times per day. D ow nl oa de d fr om is fj. ir at 1 8: 48 + 04 30 o n S un da y M ar ch 2 9t h 20 20 [ D O I: 10 .2 20 92 /IS F J. 20 17 .1 09 96 6 ]


Dissolution came after the pasasge of the Mutiny Bill, and in the general election that followed, Pitt and his supporters achieved a smashing victory. According to Cannon, the coalition was defeated by the hostility of George III, Pitt's &dquo;lie&dquo; about royal influence, the moderation of the FoxNorth group, the advantages belonging to the government in power because of the electoral system, the skillful use of printed caricature and propaganda by the Pitt forces, and the fact that the conception of party held by Fox was not readily acceptable to the country at large. The flaws in Fox's character and his personal unpopularity except with such &dquo;women of the people&dquo; as the Duchess of Devonshire are toned down. Many will question and debate the views of Doctor Cannon on the constitutional


The aim of the study was to investigate correction regarding ingroup favoritism and outgroup hostility on an implicit level. Current research revealed that people tend to make amendments for ingroup bias in the presence of an outgroup member. In order to test correction of bias implicitly, the participants received false feedback regarding their test results on an implicit test that measured racial bias. One group received false feedback about showing ingroup favoritism towards Swedes, and one group received false feedback about showing outgroup hostility towards Arabs. The reason for using two different kinds of feedback was to investigate if the participants were able to distinguish between ingroup favoritism and ourgroup hostility. The predictions were that participants who received false feedback regarding ingroup favoritism should correct for ingroup bias and the group that received feedback regarding outgroup hostility should correct for outgroup bias, but the results did not support the hypothesizes. However, the results revealed that individuals that were externally motivated to control for prejudice did correct for outgroup hostility. The results are discussed in the light of previous research.


Code-based public-key cryptosystems based on algebraic coding are considered. They are based on masking algebraic block codes with fast decoding algorithm (polynomial complexity) at random linear block code with NP-hard decoding. Assessment the strength is offered, including quantum cryptanalysis, and evaluating performance in comparison with the known cryptosystems.


The aim of the present study was to evaluate the histopathological characteristics of gastric submucosal tumors (SMTs) according to their location.


New forms of digitally-mediated labor pose several privacy concerns for workers. However, due to asymmetries in power and information, workers may be limited in the degree to which they can protect their privacy. Through my doctoral research, I examine how issues of privacy play out in the gig economy, and how they impact workers' experiences as well as how and what work gets completed.


Ms. S, age 31, is found intoxicated with empty pill bottles in her purse. She was diagnosed with bipolar disorder at age 12, but has no history of elevated mood. Was she misdiagnosed? CASE Unclear diagnosis Police find Ms. S, age 31, extremely intoxicated and drinking alcohol in her car in a city park parking lot. In the emergency room, she becomes increasingly somnolent and clinicians intubate her trachea to protect her airway. Lab testing shows she has elevated acetaminophen and lithium serum levels, and she is transferred to our hospital for further management after being started on N-acetylcysteine to treat acetaminophen toxicity. Her "ex-fiance," the father of her 2 children, saw her earlier the day of the episode and says she was distraught, intoxicated, and had several empty pill bottles in her purse. In our hospital, Ms. S' lithium level increases from 2.3 mEq/L to a peak of 5.32 mEq/L, and she undergoes hemodialysis. On hospital day 2, her serum lithium level is trending downward. After Ms. S is able to breathe spontaneously, her trachea is extubated and her hemodialysis line is removed. A psychiatric consultation is obtained, but she is unable to provide a coherent history and the treating clinicians believe she has delirium caused by multiple factors. On hospital day 3, Ms. S' delirium clears enough for her to engage in an interview, and she is transferred to our inpatient psychiatry ward for further monitoring and stabilization. She reports that she was diagnosed with bipolar disorder (BD) at age 12, when she faced multiple psychosocial stressors, including physical abuse by her mother's boyfriend. She took several psychotropics--although she cannot remember which ones--until age 14, when she stopped all medications until the year before her current hospitalization. Although throughout adolescence and adulthood Ms. S experienced chronic irritability, anxiety, impulsive behavior, poor self-esteem, abusive relationships, self-cutting, and depressed mood, she maintains that she felt worse when she was taking psychotropics and doubts the BD diagnosis. She attributes her longstanding mood issues to low self-worth, a "codependent nature," and a tendency to gravitate toward abusive relationships. Although she admits to experimenting with several illicit drugs during adolescence, she denies more recent substance use and states she drinks alcohol only once every few months. What is the most likely diagnosis that led to her overdose? a) substance-induced mood disorder b) borderline personality disorder (BPD) c) inadequately treated BD d) major depressive disorder (MDD) The authors' observations BD is underdiagnosed in several patient populations, such as individuals previously diagnosed with MDD. (1)-(3) Misdiagnosis can have severe implications, including delay in receiving treatment with effective medications (eg, mood stabilizers) or use of agents that can induce mania or rapid-cycling, such as antidepressants. Perhaps in response to this concern, in recent years clinicians increasingly have diagnosed BD in adolescents and adults. An analysis of a national database of physician practices found a 40-fold increase in office visits for BD among youth and a near doubling among adults from 1994 to 2003. (4) Although underdiagnosis of BD remains important, some researchers have suggested that overdiagnosis may be more prevalent and equally harmful. In a study of 180 patients being treated for depression in a family care clinic, there was a 21.6% initial underdiagnosis rate among those eventually found to have BD. (1) However, among 43 patients with a prior BD diagnosis, the diagnosis was not confirmed in 33%. (1) In a study of 700 psychiatric outpatients in Rhode Island, only 43% .of 145 patients who reported a prior BD diagnosis had that diagnosis confirmed. (5) Three times as many patients were overdiagnosed with BD as underdiagnosed. …


Objective:To establish the quality specification of Zhixieheji.Method: TCL method to identify the active ingredient of Zhixieheji of Cortex Fraxini,Paeoniae Radix,Atractylodes Lancea,Euphorbiae Humifusae,Radix Aucklandiae.The method is simple,specific,and reproducible;detection spots were clear.Of paeoniflorin in the injection volume 0.509-16.31 mg · L-1,and linear range of the relationship is good.The average recovery was 96.79%,RSD was 1.7%(n=6).Conclusion: The method is simple,efficient,sensitive and can be applied to quality control of Zhixieheji.


Celebration of the 1st International Conference on Housing Taxation and Public Spending, the 10th and 11th December 2004, organised by the Pompeu Fabra University, UOC and Pi i Sunyer Foundation.


This article examines changes to the role of the Church of the Holy Sepulchre (CHS) from its construction to the Latin Kingdom and argues that these changes reflect shifts in Christian perception of sacred space. When it was first built, the CHS was only a monument to the profound event of Christ's resurrection. During the Heraclian dynasty of the Byzantine Empire, the very structure of the CHS became sacred and Jerusalem became revered as the city of the Holy Sepulchre. As Muslims conquered Jerusalem in the late 7 th century AD, the CHS became increasingly emblematic of Christianity itself. Eventually, the CHS was used as a rallying cry to incite European Christians into a crusade. During the Crusader Period, the CHS was transformed into a symbol of Frankish rule. As pilgrims became more intimate with the CHS, Jerusalem's sacred geography was expanded from only the CHS to include sites encompassing all aspects of Jesus's life. With these changes to the roles of the CHS, Christians went from originally distrusting sacred space, to embrace the church as their sole axis mundus (sacred space), to accepting the presence of multiple axis mundi on earth; the CHS was among them.


The international crude oil price has the important economic significance and the political significance, the crude oil price forecast research has the far-reaching significance. There are many influencing factors of international crude oil prices. In this paper, we select the main influencing factors as predictors, and use Matlab programming method combined with BP (Back Propagation) neural network modeling to predict the WTI international oil price finally. In addition, the use of Eviews9.0, the establishment of ARIMA (Autoregressive Integrated Moving Average Model), the same forecast WTI oil prices. The two forecasting methods have the same forecasting trend and have some guidance and guidance on the international crude oil price forecasting research.


The economic feasibility of utilizing corn stover as a coal supplement in small to medium-sized, coal-burning steam-electric plants appears promising, particularly when the low sulfur emission value of corn stover is considered. Two case steam-electric power plants located in Ames, Iowa, and Peru, Indiana, are analyzed utilizing three harvest and collection systems and alternative values for several key technical and economic parameters. These results combined with data from a sample of steam-electric plants in the north central United States are used to assess the potential for this renewable low sulfur energy source.


The spin-spin coupling tensors, JXF (X ) H, C, F), in p-difluorobenzene (C6H4F2) were determined using ab initio multiconfiguration self-consistent field linear response calculations and NMR experiments performed in nematic liquid crystal phase. The theoretical spin-spin coupling constants are in fair agreement with experimental results. By supplying the experimental data analysis with some of the results of the theoretical calculations, the remaining anisotropy and asymmetry parameters pertinent to the n JCF (n ) 1, 2, 3, 4) and 5 JFF tensors were obtained in good agreement with the ab initio data. The results indicate that the tensorial properties of the fluorine couplings typically contribute a few percent to the corresponding experimental anisotropic couplings. In D2h or lower point group symmetries, the indirect coupling can even dominate the experimental dipolar coupling because of occasional cancellation of the direct part. Consequently, the contribution of JXF aniso must be taken into account when using anisotropic couplings in accurate determinations of the geometry or orientation of fluorinated liquid crystals or other molecules containing fluorine-substituted phenyl rings dissolved in mesophases.


The study aimed to investigate the associations of baseline serum albumin level and its dynamic change with type 2 diabetes mellitus (T2DM) risk in a large Chinese cohort study.


The design and construction of a high-performance, low-cost, and easy to assemble quadrature digital receiver for a home-built nuclear magnetic resonance (NMR) spectrometer is described. Critical synchronization and timing issues are considered and solutions are discussed. The performance of the receiver is compared to that of a modern commercial NMR spectrometer. Advantages of this system include excellent passband flatness and delay flatness, very sharp filter cutoff, high dynamic range, bandwidths up to 30 MHz, and perfect balance between the quadrature channels with no component matching or adjustment.


Preeclampsia (PE) is an important cause of fetal and maternal mortality around the world and there are evidences that insulin resistance has been implicated in the pathophysiology of preeclampsia. Akt/PKB pathway is stimulated by insulin and performs several vital functions as growth, survival and cellular metabolism. Objective: to investigate stimulates expression of Akt/PKB pathway in the placenta, of normal and preeclampsia parturient. Method: samples were collected from 12 normal patients and 12 PE patients, stimulate and analyzed by Western blot to quantify the proteins expression in signaling of Akt/PKB. Results: stimulation of insulin samples was confirmed when comparing stimulated groups (1.14 ± 0.10) and non-stimulated (0.91 ± 0.08), P <0.001. The Akt/PKB phosphor (Ser473) was not different in placenta of the normal (1.26 ± 0.16) and PE (1.01 ± 0.11) groups, with P = 0.237. Conclusions: there was no difference of phosphorylation in Akt/PKB pathway, after stimulation with insulin, in placentas of normal and PE patients. However, we cannot discard effects in this signaling pathway as pathophysiology of PE, because it is still necessary to analyze the substrates stimulation of this pathway.


A Hantzsch-type strategy for the synthesis of 2,3,5,6-tetrasubstituted pyridines via an oxidative coupling of β-enamine carbonyl compounds with rongalite was developed. This method employs rongalite as a C1 unit for the assembly of a pyridine ring at C-4 position, offering a facile method for the preparation of substituted pyridine derivatives with a broad functional group tolerance. In particular, this method allows us to prepare terpyridine derivatives, which are important ligands or structural fragments for catalysts and 3D metal–organic frameworks.


Partial discharge (PD) measurements have emerged as a dominant investigative tool for condition monitoring of insulation in high voltage equipment. But the major problem behind them the PD signal is severely polluted by several noises like White noise, Random noise, Discrete Spectral Interferences (DSI) and the challenge lies with removing these noise from the onsite PD data effectively which leads to preserving the signal for feature extraction. Accordingly the paper is mainly classified into two parts. In first part the PD signal is artificially simulated and mixed with white noise. In second part the PD is measured then it is subjected to the proposed denoising techniques namely Translation Invariant Wavelet Transform (TIWT). The proposed TIWT method remains the edge of the original signal efficiently. Additionally TIWT based denoising is used to suppress Pseudo Gibbs phenomenon. In this paper an attempt has been made to review the methodology of denoising the PD signals and shows that the proposed denoising method results are better when compared to other wavelet-based approaches like Fast Fourier Transform (FFT), Discrete Wavelet Transform (DWT), by evaluating five different parameters like, Signal to noise ratio, Cross-correlation coefficient, Pulse amplitude distortion, Mean square error, Reduction in noise level.


In this paper, a thermo-hydrodynamic model of the bump foil thrust gas bearing is developed, which solves the coupled gas film three-dimensional energy equation, non-isothermal Reynolds equation, and the foil deformation equation. The effects of bearing speed, thrust load, and external cooling gas on the bearing temperature field are calculated and analyzed. The test rig of foil thrust gas bearing was built to measure the bearing temperature under different working conditions. Both simulation and experiment results show that there exist temperature gradients on the top foil both in the circumferential and radial directions. The simulation results also shows that the top foil side of the gas film has the highest temperature value in the entire lubrication field, and the position of highest temperature moves radially inward on the thrust plate side as the rotor speed increases. The gas film temperature increases with the increasing rotor speed and bearing static load, and rotor speed has greater effects on the temperature variation. Cooling air flow passing through the bump foil is also considered in the simulations, and the cooling efficiency decreases as the mass of gas flow increases.


This paper studied the measurement precision of the electronic compass used in VSAT(very small aperture terminal).The basic principle of the measurement was discussed in detail,and the error mathematical model of the measurement was derived.The cause for the increase of the roll angle measurement error with the increases of the pitch angle was analyzed and a novel method for improving the measurement precision was proposed based on the above analysis.The simulation and experiment results show that the novel method can remove the influence of pitch angle on the roll angle measurement and can improve the accuracy of heading measurement effectively.The application of the novel method shows that the roll angle accuracy is approximately 0.2°and the heading angle accuracy is approximately 0.5°with a turntable pitch angle of 30°.


We present the results of our hard X-ray and gamma-ray study of the LMXB Sco X-1 utilizing INTEGRAL data as well as contemporaneous RXTE PCA data. We have investigated the hard X-ray spectral properties of Sco X-1 including the nature of the high-energy, nonthermal component and its possible correlations with the location of the source on the soft X-ray color-color diagram. We find that Sco X-1 follows two distinct spectral tracks when the 20-40 keV count rate is greater than 130 counts/second. One state is a hard state which exhibits a significant high-energy, powerlaw tail to the lower energy thermal spectrum. The other state shows a much less significant high-energy component. We found suggestive evidence for a correlation of these hard and soft high-energy states with the position of Sco X-1 on the low-energy X-ray color-color diagram. We have searched for similar behavior in 2 other Z sources: GX 17+2 and GX 5-1 with negative results.


In this paper, we developed Boolean matching techniques for complex programmable logic blocks (PLBs) in LUT-based FPGAs. A complex PLB can not only be used as a K-input LUT, but also can implement some wide functions of more than K variables. We apply previous and develop new functional decomposition methods to match wide functions to PLBs. We can determine exactly whether a given wide function can be implemented with a XC4000 CLB or other three PLB architectures (including the XC5200 CLB). We evaluate functional capabilities of the four PLB architectures on implementing wide functions in MCNC benchmarks. Experiments show that the XC4000 CLB can be used to implement up to 98% of 6-cuts and 88% of 7-cuts in MCNC benchmarks, while two of the other three PLB architectures have a smaller cost in terms of logic capability per silicon area. Our results are useful for designing future logic unit architectures in LUT based FPGAs.


This paper describes a MATLAB package for dynamic optimisation of processes. The package dynopt searches for profiles of decision variables which optimise a given performance index under specified constraints. The package uses the method of orthogonal collocations on finite elements and several case studies are successfully tested. The MATLAB source code is freely available at the package web page http://www.kirp.chtf.stuba.sk/fikar/research/dynopt/dynopt.htm.


Considering entrepreneurship the domain with the greatest potential for creativity and innovation, any investigation on this field is recommended, in order to reveal new aspects that can influence the small enterprises development. From this point of view, female entrepreneurship represents an important source of innovation, only partially exploited or even forgotten.


The compelling question of our existence, How shall I live? can be pursued through philosophy, art and education when tied to Aristotle's maxim, 'people who know most live best'. The ancient debate between Plato and Aristotle, however, sets philosophy against art due to the nature of understanding and whether the immediacy of emotions elicited by art can aid learning. Today we appreciate emotions have a cognitive role to play, especially in gaining practical wisdom. In knowing how we feel, we know what we think. Both philosophy and art seek truth; one through logic, the other through aesthetic intelligence which relies on intuition, senses and feelings in order to penetrate deeper, ineffable mysteries of life as well as illuminate the malaises of modern society and entrenched habits of mind. Art takes us out of ourselves and reveals limits of morality, all of which have enormous implications for education. In guiding students towards what is worthwhile, teachers strive to find moral methods of initiation and facilitate the education of feeling. The creative writing classroom provides manifold opportunities for development of the whole person. In reading literature, we practice moral discernment that suggests compassion for people as qualitatively unique beings, which reduces the distance between ourselves and the 'other'. Good literature is difficult; we must face reality but are offered ways to transcend suffering and death by becoming part of a larger realm of life, resulting in the desire to change our lives, see more and be touched more by life. Creative writing is even more immediate; our words reveal who we are and the views we hold. The learning curve is great as we take responsibility for our shortcomings and return to esteemed authors for models of moral vision. The literary canon mentors writers with high examples of creativity, imagination and technique. Experts divide on teaching writing; some believe in genius, others in skills and knowledge, but much can be encouraged in beginners if they naturally persevere and work hard. Serious engagement with literary reading and writing offers the possibility of achieving a balance between ideals and reality, heart and mind.


This paper summarizes the observation and nursing of patients with postoperative complications following percuta-neous transhepatic cholangiogrphic drainage(PTCD)and biliary tract stent implantation for malignant obstructive jaundice.A-mong thirty-two patients,eight had postoperative complications,including two with biliary tract hemorrhage,four with biliary tract infection,one with pneumothorax and one with bile leakage.All the thirty-two patients recovered well in clinical symptoms and quality of life.To attach importance to psychological nursing and postoperative health education are the key points in nursing care of patients with PTCD,which play important roles in alleviating clinical symptoms,improving treatment outcome and promoting the patients' quality of life.


Within the Ecuadorian market competitive, it is important for all industries hone their procedures so that you can get a production line with a much lower price. This project aims to provide a small company producing micro green boulders necessary tools to achieve this goal.
With the use of sanitary materials, to design a machine that is capable of grinding banana cooked and process, with the final result in bolon banana perfectly conformed to this you try to automate the process so that minimal human involvement is required.
For this the requirements requested by the customer for the design of the machine and the availability of materials readily available in the local environment is taken into account, since they are not machines of this type, which is designed here is considered a prototype so its cost will tend to be higher, however try to use easier and less expensive to obtain the final machine materials.
It should be emphasized that this design may be subject to further improvement, ie correction of probable and defects that may occur during production that is not part of this project, this is mainly because as mentioned in the previous paragraph is a prototype and can contain design flaws.


In the field of catalysis, the support of the catalyst is often composed of hollow carbon materials. In order to monitor the preparation of nitrogen-doped carbon-based bimetallic copper-cobalt catalysis and its hydrogenation reaction in furfural, using m-aminophenol as the nitrogen source, formaldehyde as a carbon source, and P123 as a template agent, a nitrogen-doped bimetallic copper-cobalt mesoporous carbon catalyst Cu-Co@N-MPC-500 was synthesized by the hydrothermal method. The morphology, structure, and chemical composition of the catalyst were analyzed by means of TEM, XRD, BET, and XPS, respectively. The results show that the nitrogen-doped mesoporous carbon has a stable structure, uniform pore size distribution, and the nano-copper-cobalt particles are uniformly dispersed in the mesoporous carbon surface. Through furfural hydrogenation, the catalyst selectivity and cycle stability were discussed. Under the furfural conversion rate of 96.1%, the yield of cyclopentanone could reach 76.2%. After 5 cycles, the catalytic efficiency of the catalyst did not decrease significantly. It shows that Cu-Co@N-MPC-500 has excellent application prospects in the field of industrial production.


As a promising technology for renewable energy production and wastewater treatment, microbial fuel cell (MFC) is quite new and significantly important. The conventional two chamber MFC consisted of an anaerobic biological anode and aerobic biological/abiotic cathode separated by proton exchange membrane. On bio-anode, organic compounds were oxidized by microbes to produce proton (H+), electron and carbon dioxide. H+ diffused to cathode, electron travelled through outer circuit to cathode, where they combined with oxygen to form water. The cost of membrane and aeriation device and the internal resistance were the main limitation of a conventional two chamber MFC. To eliminate the aeration device and reduce the internal resistance, air-cathode single chamber MFC (SCMFC) was introduced. SCMFC was simple in design and cost-effective. However, formation of aerobic biofilm on air-cathode fouled the attached Pt-catalysts on it and subsequently reduced the system performance. Therefore, a suitable mitigation measure was essential to suppress the growth of biofouling on cathode for cost-effective application of MFC in wastewater treatment and bio-energy recovery. The current study carried out to investigate the effectiveness of chloramphenicol as anti-biofouling agent on Pt-coated cathode to suppress the growth of aerobic biofilm in SCMFC operated in batch mode and compared the findings with a similar conventional SCMFC with Pt-coated air-cathode. The study was done by using two MFCs, i.e., one with conventional Pt-coated air-cathode (MFC-1) as control, and another with antibiotic mixed Pt-coated air-cathode (MFC-2). In the control MFC-1, the maximum generated cell potential of 0.82 V reduced to 0.62 V during three months operation v due to biofouling development on Pt-coated air-cathode. Besides, the control system achieved 95% COD removal by 5 days hydraulic retention time (HRT). However, with the newly developed antibiotic mixed Pt-coated cathode in MFC-2, the system achieved maximum cell potential of 0.85V with 95% COD removal by 10 days HRT. The higher HRT in MFC-2 demonstrated that there were no/less-aerobic biofilm grown on the cathode. Therefore, the rate of COD removal was slower compared to that in the control MFC-1 where two different groups of biofilm were involved in reducing the COD. The maximum columbic efficiency (CE) achieved in control MFC-1 was 8%, whereas, the maximum CE achieved in newly developed MFC-2 was 12.5%. A significantly high CE in MFC-2 explained that the major fraction of COD Civil and Architectural Engineering Civil and Architectural Engineering Department-College of Engineering-Sultan Qaboos University was removed by the exo-electrogenic microbes on anode that were contributed to higher CE generation. The increment in CE by applying antibiotic on cathode indicated the absence of cathodic aerobic biofilm and the removal of COD was solely done by the anodic biofilm. Therefore, the application of antibiotic coating on cathode can suppress the growth of cathodic biofouling without interfering the other bio-electrochemical properties (COD removal, power recovery, pH change) of the system. However, the release of antibiotic chemicals from cathode to electrolyte could negatively affect the anodic biofilm performance in the long-term operation. Therefore, more studies were needed for long-term investigation with this antibiotic coated cathode or exploring the application of other antibiotics on cathode to make the system costeffective and ecofriendly.


Silica microspheres self-assembled on the outer surface of a standard single-mode silica optical fiber are investigated. The three dimensional colloidal crystals of FCC structure coating on the cylindrical substrate are fabricated through isothermal heating evaporation induced self-assembly. The resulting photonic crystal cylindrical annulus is characterized by scanning electron microscopy (SEM). The SEM images illustrate the [111] and [100]-oriented regions, besides the two zones regularly intercrossed pattern. Qualitative analysis and discussion are carried out for the arrangement of various oriented regions.


The purpose of the Environmental and Social Management Plan (ESMP) is to summarize the management and implementation of the project's environmental commitments resulting from the ESIA (i.e. mitigation and monitoring requirements). The ESMP includes all measures that will be incorporated during constructions and operations to reduce or eliminate significant potential environmental and social impacts. These measures are gathered into a mitigation plan. The mitigation plan provides a number of recommendations, including standard HSE measures to be implemented before starting construction and during the works. These are required by law and follow best practices, and also incorporate the recommendation from the Risk Assessment of the project. Overall, these are considered relatively common for the execution and control of risks of the project. Measures of prevention, control and protection related to technological risk assessment and occupational hazards have to be implemented through health and safety planning documents, including the general coordination plan on safety and health protection and specific safety and health protection plans. These will be prepared, implemented and monitored by the main contractor and companies working on-site (i.e. subcontractors). The environmental monitoring plan gathers all monitoring measures recommended as part of the ESIA before, during and after the construction activities. This plan is a tool to verify, through experience/or direct observation in the field, the accuracy of the impact assessment and the effectiveness of proposed mitigation or compensation measures, especially where some uncertainties remain. As a result of the impact assessment, the ESIA recommends further studies and field investigation including sediment transport modelling, marine surveys and socioeconomic surveys.


Magnetocaloric materials with a Curie temperature near room temperature are of interest for application in high-efficiency solid state cooling. There are several promising families of materials including the LaFe13-xSix system which offers large magnetocaloric entropy change, low magnetic and thermal hysteresis, and tunability of the metamagnetic transition by introduction of interstitial hydrogen or partial substitution on the La or Fe sites. There is a large amount of literature on the properties and mechanism of the magnetocaloric effect in this material system, and more recently our group and several other groups have discussed the origins of the dynamics of the metamagnetic transition and its relation to magnetic hysteresis. Nevertheless, although extremely informative in other systems, there has been little spatially resolved information concerning the nature of the magnetic transition in this system. Here we use scanning Hall probe imaging to study LaFe13-xSix polycrystalline samples with x=1.2 prepared by induction melting to resolved the local static and dynamic magnetic properties. We find that the local properties of the magnetic transition are governed by chemical inhomogeneity rather that demagnetization effects associated with sample geometry.


Growth, mortality and stock assessment of big eye croaker Pennahia macrophthalamus(Bleeker) is
reported in the present communication. The asymptotic length of this species is estimated as 260mrn and
growth coefficient 1.20 per year.The total, natural and fishing mortalities were estimated as 3.24, 2.81 and
0.43 respectively.The stock assessment studies were carried out using length cohort and Thompson & Ben
model. The result of this study shows that there is no decline in the catch of this species at the present level
of exploitation. However, it is observed that even if the fishing efforts are doubled the catch can go up by
only 12.74%.Therefore, further increase in the efforts is detrimental to the stock of Pmacrophthalamus and
the returns may not be remunerative.


ABSTRACT For years there has been a failure to show the relevance between the application of religious text within social work and the social sciences. This paper provides a functional framework on the reason for the separation between social sciences and religious studies and then uses the Genesis account of Noah and the flood to show how the two can be integrated for peacebuilding, reconciliation, and healing. The paper applies the Noah story to micro, mezzo, and macro applications of social work practice and concludes with a call for a deeper integration of religious text into social work practice.


Using a pragmatic approach, the LIRA‐PRIME trial aims to address a knowledge gap by comparing efficacy in controlling glycaemia with glucagon‐like peptide‐1 analog liraglutide vs oral antidiabetic drugs (OADs) in patients with type 2 diabetes (T2D) uncontrolled with metformin monotherapy in primary care practice. We report the study design and patient baseline characteristics.


A (cid:142) ve-component, data assimilative marine ecosystem model is developed for the high-nutrient low-chlorophyllregion of the central equatorial Paci(cid:142) c (0N, 140W). Identical twin experiments, in which model-generated synthetic 'data' are assimilated into the model, are employed to determine the feasibility of improving simulation skill by assimilating in situ cruise data (plankton, nutrients and primary production) and remotely-sensed ocean color data. Simple data assimilative schemes such as data insertion or nudging may be insuf(cid:142)cient for lower trophic level marine ecosystem models, since they require long time-series of daily to weekly plankton and nutrient data as well as adequate knowledge of the governing ecosystem parameters. In contrast, the variational adjoint technique, which minimizes model-data mis(cid:142) ts by optimizing tunable ecosystem parameters, holds much promise for assimilating biological data into marine ecosystem models. Using sampling strategies typical of those employed during the U.S. Joint Global Flux Study (JGOFS) equatorial Paci(cid:142) c processstudy and the remotely-sensedocean color data availablefrom the Sea-viewingWide Field-of-view Sensor (SeaWiFS), parameters that characterize processes such as growth, grazing, mortality, and recycling can be estimated. Simulation skill is improved even if synthetic data associated with 40% random noise are assimilated; however, the presence of biases of 10–20% proves to be more detrimental to the assimilation results. Although increasing the length of the assimilated time series improves simulation skill if random errors are present in the data, simulation skill may deteriorate as more biased data are assimilated. As biological data sets, including in situ, satellite and acoustic sources, continue to grow, data assimilative biological-physical models will play an increasingly crucial role in large interdisciplinary oceanographic observational programs.


Ficus variegata Blume is specific plant of east Kalimantan. Flavonoid compound of Ficus variegata Blume was isolated by vacuum liquid and column chromatography, with previously extracted by maceration method using n-hexane and methanol, and fractination using ethyl acetate solvent. Eluent used in isolation were n-hexane:ethyl acetate (8:2). The results of elucidation structure by using spectroscopy methods (GC-MS, NMR, and FTIR) was obtained 5-Hidroxy-2-(4-methoxy-phenyl)-8,8-dymethyl-8H-pyrano[2,3-f] chromen-4-one. This compound has an antibacterial and antioxidant activities.


Ultrasonography has been a valuable diagnostic tool in most fields of medicine since the early 1970s and it is widely used by physicians in clinical practice. Conventional two-dimensional (2D) ultrasound has the ability to visualize only sagittal and transverse planes. Reflections are obtained in transverse planes in 2D ultrasounds while at certain angles in three-dimensional (3D) ultrasounds thus the images produced by 3D ultrasounds are more accurate. However, translation of 2D scan to 3D scan takes time (approximately 15 minutes). One of the new applications in this field is automatic measurements with software called sonography-based automated volume calculation (SonoAVC). The application of SonoAVC is employed in observation of follicle growth in controlled ovarian hyperstimulation (COH) and in pregnancy for evaluation for embryo and fetus.


Inspired by the catalytic mechanism of cytochrome P450 enzymes, we have evolved a fatty acid hydroxylase, P450BSβ, into a decarboxylase after four rounds of saturation mutagenesis that now predomin...


Zolpidem is a hypnotic drug from the imidazopyridine family that is chemically distinct from benzodiazepines (BDZ). Contrary to classic BDZ, zolpidem acts selectively on α 1 subunit-containing GABA-A benzodiazepine (BZ1) receptors. There are a considerable number of zolpidem dependence case reports in the recent literature. Regarding the similarities of zolpidem and BDZ in pharmacodynamic and addictive characteristics, it has been suggested that recommended detoxification protocols for short half-life BDZ may also be useful in high-dose zolpidem withdrawal management. Safety and effectiveness of phenobarbital for inpatient BDZ detoxification has been established and it may be useful for zolpidem detoxification, as shown in two case reports presented here.


Paleontological datasets often have large amounts of missing entries that result in multiple most parsimonious trees. Highly incomplete and conflictive taxa produce a collapsed strict consensus and several methods have been developed for identifying these unstable or rogue taxa in optimal trees derived from phylogenetic analyses. In addition to decreasing consensus resolution, incomplete or conflictive taxa can also severely affect the support values of phylogenetic analysis in paleontological datasets. Here, we explore a protocol for the identification of taxa that decrease jackknife support values in parsimony analysis. The taxa identified are excluded from majority rule jackknife trees, revealing nodes that have either low or high support irrespective of the uncertainties in the placement of unstable taxa. A recently published dataset of coelurosaurian relationships based on 164 taxa and 853 characters is explored using this protocol; our protocol detects a total of 40 unstable taxa as the most detrimental for node supports. Major clades that are well supported in the reduced jackknife tree include Coelurosauria, Maniraptoriformes, Compsognathidae, Ornithomimosauria, Alvarezsauroidea, Therizinosauria, Oviraptorosauria. Clades with moderate support instead include Maniraptora, Pennaraptora, Paraves, Dromaeosauridae, Troodontidae, Anchiornithinae, and earlydiverging clades of Avialae.


During recent years institutionalism has become a major theme in political theory. A radical version of institutional impact is offered by March and Olsen who attack behaviouralism as well as public choice. This paper first argues that their basic tenets correspond to Hegelian reasoning and second, claims that they fall prey to the very same critique which has been launched against Hegel from an empirical as well as a normative point of view.


Part 1 Models of understanding human development: attachment theory, Jane Aldgate life stages theory, Alastair Gibson psychodynamic approach, Judith Brearley structural/conflict models, Ann Davis loss and bereavement, Gerard Rochford contributions from other disciplines to social work, Pauline Hardiker. Part 2 Models of social work intervention: behavioural, Barbara Hudson crisis theory, Kieran O'Hagan task centred, Peter Marsh counselling - cognitive, Windy Dryden, psychodynamic, Michael Jacobs community social work, Stuart Watts life space work, Colin Keenan.


Abstract : Sediments beneath the Beaufort Sea near Prudhoe Bay, Alaska, were probed at 27 sites using a static cone penetrometer to determine engineering properties and distribution of material types, including ice-bonded sediments. The probe provided both point and casing resistance data and thermal profiles. At five sites these data were correlated with information from adjacent drilled and sampled holes. These control data and the quality of the probe information permitted profiles of sediment type and occurrence of ice-bonded material to be developed along three lines that included various geological features and depositional environments. Material properties were quite variable in the upper 14 m of sediments probed. In general, softer, finer-grained sediments occurred in the upper layers, while penetration refusal was met in stiff gravels to 10 to 12 m below the seabed. Seabed temperatures during the study were all below 0 C. However, because of uncertainties in freezing point values caused by brines, evaluation of the penetration resistance data was required to identify the occurrence of ice-bonded sediments. The coupling of thermal and penetration resistance data revealed that seasonally ice-bonded sediments occurred where the sea ice froze back to or near the seabed. Deeper, perennially frozen sediments also appeared to be present at several probe sites. The penetration data obtained can be used to aid in the design of shallow and deep foundations in both ice-bonded and unfrozen subsea sediments. (Author)


This study aims to determine the income of farmers and the efficiency of buffalo farming carried out by the people of Sijunjung Regency. The research was conducted in the Sijunjung Regency area, namely on farmers in selected areas in November 2020. This study used a survey method with 50 respondents as buffalo farmers. The data analyzed is data for the current year, namely 1 October 2019 1 September 2020. Based on the results of the study, it can be concluded that the income of the Sijunjung Regency breeder community from buffalo farming is Rp. 6,644,344/breeder/year. Then from the analysis of the R/C ratio, a value of 8.07 was obtained, which means that the efforts made are efficient and feasible to continue.


Early migration scholarship on the transnational family has tended to portray stay-behind children as passive recipients of care and helpless victims of transnational migration. Despite the increasing sophistication of the literature highlighting children's active roles, empirical studies on transnational families focusing on understanding children's changing agency through time are still limited. We aim to fill this lacuna by offering a longitudinal perspective on children's changing agency in using communication technologies. Focusing on the "transition to adulthood" experiences of Filipino and Indonesian stay-behind children (from 9–11 years old to 17–19 years old), we examine how their agentic behavior and practices change in using information and communication technologies to negotiate power and autonomy within the transnational family. We show how the changes in the children's specific life course and the shifting digital divide that accompany these transitions shape the possibilities and limits to children's empowerment and agency in enacting family transnationally.


Introduction:
 It is well understood that the occurrence, progress, and treatment of heart failure, which is a leading cause of death worldwide, is sex-specific. Over the past decade, the majority of efforts in myocardial regeneration have been centered on cell-based cardiac repair. A promising cell source for these efforts is patient-specific human cardiomyocytes (CMs) differentiated from human inducible pluripotent stem cells (hiPSCs). However, successful use of hiPSC-CMs faces a major limitation, the poor engraftment and electromechanical coupling of transplanted cells with the host myocardial tissue. Magnetic nanoparticles (NPs) demonstrate great potential to address this challenge for treating heart failure via cell therapies. In particular, superparamagnetic iron oxide NPs (SPIONs) have been used to label hiPSC-CMs and, with the aid of external magnetic field, improve their engraftment and electromechanical coupling in the heart tissue. However, the critical role of cell sex in the uptake and labeling efficacy of NPs has not been evaluated.

 Hypothesis:
 Significant differences in the molecular and structural (e.g., actin structures and distribution) characteristics of male and female hiPSC-CMs affect their labeling efficacy with SPIONs.

 Methods and Results:
 To test our hypothesis, we first performed RNA-Seq analysis on three male and three female (healthy) hiPSC-CM lines. The normalized outcomes were analyzed by edgeR package. We next calculated gene-expression differential between male and female CMs. The results revealed 58 genes with significant differences between the male and female cells (p-value < 0.01). The highest observed sex-specific variation in genes was related to tophit gene (MEG3: logFC = 7.32, P-value = 5.63e
 -06
 ), which is the maternally expressed imprinted gene with a great role in cardiac angiogenesis. Among the identified genes, a number of those were related to the cellular cytoskeletal structures including actin. We probed possible structural differences between actin filaments organization and distribution of male and female hiPSC-CMs using the stochastic optical reconstruction microscopy (STORM) technique. The results demonstrated substantial differences in organization, distribution, and morphology of actin filaments between male and female CMs. Incubation of SPIONs with male and female hiPSC-CMs revealed higher uptake of NPs (~ 3 folds) in female cells as compared to the male cells. The significant differences in the uptake of SPIONs by male
 vs.
 female cells could be attributed to the distinct organization, distribution, and morphology of actin in male
 vs.
 female cells.

 Conclusions:
 Our results indicate that male and female hiPSCs-CMs respond differently to the labeling SPIONs.


High population growth in a region commonly pushes the government to fast provide public facilities in order to fullfil the public needs. Along with it, one of the challenges that faced by the urban center of Pattallassang Distric in Gowa Regency is rapid land convertion due to high land demand to provide public facilities. This urban area is highly populated and has intense activities because not only it functions as center of government but also as a Special Economic Zone (KEK) of the region. The aim of this research is to evaluate the landuse realization in Gowa Region, between what is found in reality with what has been planned in regional spatial plan (RTRW), as well as to identify the contributing factors behind the discrepancies. This research was conducted from September 2019 to February 2020 (6 months). The data and information were collected through literature study related to land suitability evaluation methods, influencing factors, and field survey. The research used method of spatial analysis using overlay techniques with the help of software ArcGIS 10.1, scoring analysis to define the suitability value, and qualitative descriptive analysis to determine factors that contribute to the discrepancy between existing landuse and the RTRW document. The results showed that among the many landuse discrepancies, the residential landuse has the lowest value of suitability value of 24%. Economical and environmental factors may play important roles in this discrepancy.