The current article presents the results of interdisciplinary research conducted in Israel over the last few years. This research aims to characterize the traditional varieties of the Holy Land, as well as the means of production and characteristics of the wines made from these varieties. In a previous paper, we suggested that unique apparatuses located at Hirbat Hablta are related to the production of a sweet wine named "Helioston," and presented the historical sources that support this claim. In the current article, we discuss the historical sources relating to Cyprus ("Cafrissin") wine and Helioston wine; we propose that the Cafrissin wine, mentioned as an ingredient of the incense used at the temple in Jerusalem, is a wine produced in a similar manner (the partial drying of grapes) to Helioston wine. We propose that in both cases, the wines were high in alcohol and contained high residual sugar content. To demonstrate the possibility of producing wine of this kind in natural, open conditions in the summer climate of the central mountains of Israel , we conducted an experiment that entailed the partial drying of endogenous and European grapes and the processing of these grapes into wine. The experiment achieved high sugar levels of above 300 Brix, and the grapes were fermented into wines high in alcohol and sugar that harbored unique aromas. This practical research emphasizes the nutritional importance of this type of wine in antiquity, and points to its potential for the modern winemaking market.


The authors investigated modifying schedules to increase the drying rate ( DR ) and reduce the total drying time for Tectona grandis L. wood from juvenile plantations. The initial MC ranged from 92 to 115%. A conventional teak schedule was used as the basis for developing two faster drying schedules and for comparison.  The modifications resulted in a reduction in drying time from 125 to 105 hours, a 16% energy savings and less than 1% MC variation in dried lumber; however, this change caused a slight decrease in wood quality. The relationship between the DR, the lumber's MC, and drying time was modeled. As expected, the dry-bulb temperature and wet-bulb depression had the greatest influence on DR ; however, an inflexion point was found in the relationship between DR and MC at a 40% MC for all three drying schedules. The inflection point indicates when diffusion becomes the primary driving force of moisture movement, therby llimiting the DR, and indicating when the kiln conditions should be accelerated to minimize the total drying time. DR hour should remain over 0.5%/hour (high value for tropical species) for the first 72 hours (3 days), until the lumber reaches 40% MC and then be lowered to 0.5%/hour until drying is completed.


Biodegradation Bioremediation of waste oil sludge through biodegradation using microorganisms still has an impact on the environment, because produces of gas emissions which causes to the global warming. The purpose of this study was to determine the production of carbon dioxide, methane, and nitrous oxide gas in biodegradation of waste oil sludge by using types of bioactivator from soil as the microbe inoculums sources was compost, mangrove and forest soil with adjusting the ratio of C:N:P of 360:60:1 to optimize the biodegradation condition. The results show that the addition of bioactivator on the treatment of waste oil sludge can increase the biodegradation process. The results show that the compost bioactivator treatment is 72 percent decrease in oil sludge, the forest soil bioactivator treatment of 58 percent and then the mangrove soil bioactivator of 46 percent. The observation of gas production obtained the highest concentration of carbon dioxide was produced on compost bioactivator treatment of 0.91 ppm on the 25 day, production of methane on compost bioactivator treatment was 0.66 ppm on the 25 day and production of nitrous oxide on the mangrove soil bioactivator treatment of 0.19 ppm on the 30 day; The decrease of hydrocarbon waste oil sludge and increased gas production are also associated with an increase in the population number of hydrocarbon degrading bacteria at all bioactivator treatments.


Contents: Introduction Picturing masculinities in the Orient: Frederic Leighton The gentleman's body and class anxiety: Fildes, Holl and Herkomer The utopia of inverts: Henry Scott Tuke Masculine death: John Singer Sargent Conclusion: man's body Bibliography Index.


This paper proposes a wide dynamic range CMOS APS pixel array using a sensitivity control gate (SCG) without much degradation in optical performance. The proposed method is realized by adding a polysilicon control gate over the photodiode (PD) area, which adds MOS capacitance to the original PD capacitance. While a single control gate over PD can maximize the range of capacitance PD can have, it also has the maximum light absorption in the gate. By using SCG with holes, fringing capacitance of the control gate can be utilized to effectively sustain the total capacitance range while increasing the QE.


The effects of irrigation treatments and seed mixtures on yield, quality and seasonal distribution of pasture production were studied at Saanichton, British Columbia. Ten acre-inches of water in five equal applications proved to be the best irrigation treatment. It increased production by an average of 85 per cent during 4 years and by 129 per cent in the very dry 1953 season. Plots irrigated with 15 acre-inches of water reached wilting point down to the 12-inch depth during periods of severe drought, while at other times water was lost through deep percolation. Irrigation increased the protein and decreased the fat contents of the herbage but had little effect on the crude fiber and ash content.Orchardgrass and Ladino clover in a mixture proved to be outstanding for uniform production throughout the season. Orchardgrass produced a better balance of grass to legume in the herbage than Alta fescue and perennial ryegrass.


Abstract This research aimed to examine the type and frequency of different types of antibodies in patients treated with blood.In Chaiyaphum Hospital And used as a guide for preparing compatible blood to patients appropriately, accurate, fast and secure as possible. We evaluated the type of blood group antibodies of patients in Chaiyaphum Hospital. Result : Between 1th October 2554 - 30th September 2555. About 15,755 cases were screening and early detection for type of antibody (antibody screening & antibody identification) with a test tube (standard tube test) and gel test using standard cells O1, O2 (screening cells) and panel cells were also produced by the National blood Centre Thai Red Cross society. This study found that. Sera were positive with the antibody in 541 patients (3.43%) and could not identify the antibodies in 478 cases (88.35%). In the positive antibody group was found the MNS antibody system the most. About 221 cases (40.85%), Rh antibody system was found by 112 cases (20.70%), Auto antibody system in 22 patients (4.06%), Lewis antibody system in 17 patients (3.14%), Kidd antibody system in 14 patients (2.58%), Duffy antibody system 7 cases (1.46%), Diego antibody system in 6 (1.25%), P system antibodies in 2 cases (0.42%), I antibody system in 2 cases (0.42%) of the study. Conclusions : The types of frequency antibodies were found in patients in Chaiyaphum Hospital. It is useful in the preparation of blood to patients who require frequent blood transfusion such as in patients with thalassemia. To prevent the antibody from the blood. Should prepare blood types and Antigen E-c- Mi (a-) back up to the patient to be treated by giving blood regularly. And in patients with multiple antibodies. Blood banks are able to get blood from the Red Cross Blood Service to spare, before the patient is treated.


The Von C0 is one of the newest additions to the Nhac Tai Ti2, or --am er music of South Vietnam. Inasmuch as NhaTai TYFperformances vary according to the moods and availabilitj of the players, a versatile style has evolved which may be performed by as few as one or as many as eighteen musicians.3 The instruments used are primarily plucked and bowed chordophones. The ensemble is never without a woodblock called s&ng lang which the leader uses to punctuate the phrases and occasionally an endblown flute is added. A single vocalist, usually female, is considered essential though many performances are completely instrumental.


This paper aims to develop metrics for the evaluation of color rendition of LED light sources in merchandising spaces. Influential factors for a LED light source, such as correlated color temperature, illuminance, and color rendering index (CRI) have been proposed as part of a sustainable lighting application strategy. However, there are several problems with the CRI. The factor analysis used in this research is focused on the properties of the LED light source, and various combinations of twenty existing and proposed alternative metrics were analysed for the LED illumination evaluation method. LED spectral power distribution should be designed for high luminous efficacy as well as good color rendering. Optimised LED light source increases color saturation and has a good color discrimination capability. Our results indicate that two complementary assessments should be developed to characterise the features of a LED light source for merchandising lighting application. Saturation enhancement or hue shift are core common categories for different types of merchandising lighting. For example, a combination of CRI below 80, high enough CRI R9, and Color Quality Scale (CQS) is recommended in supermarkets, while CRI over 80, sufficiently high CRI R9, and Feeling of Contrast Index (FCI) is recommended for lighting in clothing retail stores.


The CCR DEA model only divides the DMU into efficient or inefficient. However,the super-efficient DEA which is improved from the CCR DEA mode was applied to evaluating the productivity of construction industry during the period of 2007 ~ 2011. The results show that,China's construction industry production efficiency generally presents a steadily rising trend from 2007 to 2011,only in 2011 due to a slight decline in Real estate investment cooling; at the same time,while construction enterprise expanded the scale,the efficiency generally was declined. As a whole,there are significant regional differences in China's construction industry production efficiency,and the comprehensive efficiency of the eastern region is obviously higher than the central and western areas. Therefore,this paper suggests that the government should increase investment in technology innovation; Secondly,the government should encourage construction companies to become bigger,stronger and own their brand,meanwhile,to control the scale of construction enterprise appropriately,in order to avoid the too fast scale expansion; Finally,the government should give the western construction enterprise key support,and increase the eastern and western regional cooperation.


The article gives data of many years obtained during the investigation of cultivars and cultivar-rootstock combinations in the intensive orchard. It has been revealed that the use of dwarfing rootstocks as inserts provides a weakening action and allows cultivating dwarf trees with compact canopy, strong trunk and good anchoring, the trees are handy for cultivation and harvesting. Dwarfing inserts 57-366 and G-134 have effected the tree vigorousness most of all. The fruiting periodicity of cultivars with dwarfing inserts has been studied and data are given. The apple cultivar Imrus has showed the best precocity, high yield capacity and yield regularity in combination with best inserted rootstocks. Having analyzed the data on cropping power and specific yield load on canopy volume unit, crown projection area and trunk crossing section area according to the age periods, it was stated that at the age of 20 years studied cultivars on dwarfing inserts gave high yields. The tendency of increasing yields with the age was also noted. It proves the continuous productive cropping period of cultivars under use of inserted rootstocks.


The structures with which male spiders transfer sperm to females are unique among all animals in several respects. From the ancestral arachnid sperm transfer mechanism via an external spermatophore (Thomas & Zeh 1984), male spiders have evolved to transfer sperm to the female by using their pedipalps, a portion of the male's body that is not associated directly with his primary genitalia. Similar but independent evolution of "secondary" genitalia involving different male structures that subsequently come under sexual selection has occurred in several other arachnid orders (solifugids, ricinuleids, some pseudoscorpions, and mites— Kaestner 1968; Thomas & Zeh 1984; Alberti & Michalik 2004), as well as in other groups, such as odonate insects. The use of the pedipalps as secondary male intromittent genitalia is a unique synapomorphy of spiders, without convergence in any other arachnid, and without a single known reversal. More important, however, is the fact that the portion of the male spider's pedipalp that has become specialized to receive and transfer sperm, the palpal "bulb", is apparently unique among all animal genitalia in that it lacks nerves, and thus also lacks sense organs and muscles (Eberhard & Huber 1998b). Much of this chapter will be dedicated to exploring the consequences of this lack of nerves for the evolution of spider genitalia. We will concentrate fi rst on males because we believe that this lack of nerves in males has probably been largely responsible for many peculiarities of genitalic evolution in spiders, and then turn to females. Despite the profound differences associated with a lack of nerves, spider genitalia clearly share the overall evolutionary trend seen in the male genitalia of many other groups, in being relatively distinct morphologically even among closely related species. This pattern of sustained, relatively rapid divergent evolution in genitalia was discovered long ago by spider taxonomists (summary, Comstock 1967), and their accumulated work constitutes a treasure chest of information on how spider genitalia have evolved. Although it is possible that the generality of this trend may be somewhat overestimated due to the possible bias of some taxonomists to recognize species mostly on the basis of genitalic differences (Huber 2003a; Song 2006) (see chapter 04 in this book), there is an independent indication that sustained rapid divergence has characterized genitalia in spiders. Male spider genitalia have such a diverse array of different sclerites that it has been very diffi cult to homologize them (e.g., Gering 1953: 33; Merrett 1963; Platnick 1975; Coddington 1990; Griswold et al. 1998, 2005; Agnarsson et al.


The article is the first attempt in historiography to synthesise the issue of location of the local parliaments' assemblies in Great Poland in the early modern era, taking into account its genesis and transformation. It is based on existing, not numerous and scattered findings in the literature, and, above all, on the basis of the analysis of extensive, issued already in print, source material for local parliaments of the Poznan and Kalisz Voivodeships. The authors tried to show not only the basics of customary and legal location of the assemblies, the places where over three centuries debated the nobility of Great Poland, but also provide some of the details related to the usual place of those assemblies in Środa. The basic conclusion from the findings in this text confirms that from the second half of the 15 th century, Środa was just almost continuously the center of political meetings of the nobility of the vast territory covering two and, since 1768, three voivodeships. Besides, it has been proven that the local parliament of Great Poland in the early modern era did not have a permanent location, but only confirmed by custom and written law the place for assemblies.


To better learn the dependency relationship between nodes, we address the relationship extraction task by capturing rich contextual dependencies based on the attention mechanism, and using distributional reinforcement learning to generate optimal relation information representation. This method is called Dual Attention Graph Convolutional Network (DAGCN), to adaptively integrate local features with their global dependencies. Specifically, the samples are represented as nodes on the graph, and the relationships within and between nodes are studied. We consider the influence between node feature locations and associate each location information of the feature with other features. This allows the feature vector to contain a wider range of semantic information to enhance the ability of feature representation. We consider the information features of node dependence, use adjacent nodes to represent their own nodes, and encode the features of node relation, so as to enhance the global dependence between nodes. We sum the outputs of the two attention modules and use reinforcement learning to predict the classification of nodes relationship to further improve feature representation which contributes to more precise extraction results. The results on the common datasets show that the model can obtain more useful information for relational extraction tasks, and achieve better performances on various evaluation indexes.


The author describes changes which UDC (Universal Decimal Classification) has suffered since it became the property of the UDC Consortium. Viewed from the perspective of this new technologically advanced environment, the author discusses the justification of and the need for such a classification. The obvious need for classification, along with its unavoidable problems, is emphasized within the context of applying it for the purposes of resource discovery on the Internet. The article gives an overview of the changes in the management and the revision methods of the classification system, and it reflects on the introduction of the electronic form of the classification system which followed as a logical consequence of the system modernisation. The author, who is also the Editor in Chief of the UDC classification system, presents the plan for future revisions of the UDC that will hopefully result in its better application in the new environment.


Wuchereria bancrofti is a threadlike nematode one of the causative worm of lymphatic filariasis in which the
lymphatic and genital organs get disabled either temporarily or permanently; till date no effective drug or vaccine has been discovered to treat lymphatic filariasis. In this analysis we have predicted antigenic peptides from Wuchereria bancrofti troponin protein for synthetic peptide vaccine design against lymphatic filariasis because with a single protein subunit immune response can be generated in large population. Analysis shows predicted epitopes of Wuchereria bancrofti troponin protein are important determinant for protection against lymphatic filariasis. In this assay we have analysed the binding affinity of Wuchereria bancrofti troponin protein having 136 amino acids, which shows 128 nonamers. In this research work, we predicted CTL-epitopes by two different methods namely SVM (Support Vector Machine) and ANN (Artificial Neural Network), SVM based prediction shown sixteen valid epitopes having optimal score of 1.129 at cut off 0.36 whereas ANN based prediction shown thirty-one valid epitopes having optimal score of 1.000 at cut off 0.51. We also predicted cascade SVM based TAP binders and four potential antigenic epitopes as, 31-LRKLIRK-37, 49-DEFCALVYTVANT-61, 87-SRPTLKALLKE-97, 108-EAAVDE-113 (optimal propensity 1.223) predicted on the basis of highest local hydrophilicity; in addition to this we also have experimentally predicted tertiary structure of the two longest potential epitopes those can aid our understanding in
sequence-structure-function relationship of Wuchereria bancrofti troponin protein towards synthetic peptide vaccine design. Thus a small fragment of troponin protein can produce immune response against activity of Wuchereria bancrofti. This approach can be applied for designing subunit and synthetic peptide vaccines


Identifying an appropriate set of ``observables'' is a nontrivial task for most approaches to quantum gravity. We describe how it may be accomplished in the context of a recently proposed family of stochastic (but classical) dynamical laws for causal sets. The underlying idea should work equally well in the quantum case.


Proportionality is part of the legal framework of all regulators, particularly at the stages of interim orders and sanction. Proportionality is expressly referred to when considering sanction in the Chartered Institute of Management Accountants, Disciplinary Committee Rules 2015, rule 24(7) (in deciding what sanctions are to be imposed, the panel shall take into account the issue of proportionality). The fitness to practise rules of other bodies may state that the committee shall have regard to any sanctions guidance issued by the regulator: see, for example, General Pharmaceutical Council (Fitness to Practise and Disqualification etc) Rules 2010, rule 31(14), and Bar Standards Board, Disciplinary Tribunals Regulations 2017, rE204. The guidance itself will often say that the panel should make sure that any sanction it imposes is appropriate and proportionate, based on the individual facts of the case, and is in the public interest.


Corona virus disease 2019(COVID-19) is a multisystem disease with many unusual presentation reported worldwide. Though it mostly involves the respiratory systems, it has also potential to invade neurological system. It can spread from respiratory systems to the central nervous system. Here we report a case of 70 years old female who was diagnosed as COVID-19 case by molecular diagnosis and admitted with the features of acute ischemic stroke and later developed severe pneumonia also. The lady has radiological evidence of acute ischemic stroke and severe pneumonia as well as elevated D-dimer, lymphopenia, raised erythrocyte sedimentation rate, high C reactive protein (CRP) and serum ferritin. She was managed symptomatically for both pneumonia and acute stroke. Our case emphasizes that cerebrovascular disease in COVID-19 may simultaneously develop, increased c reactive protein, serum ferritin and D-dimer may contribute to the hypercoagulability and in the formation of acute ischemia. Elderly patients with co-morbidities like hypertension, diabetes, vascular disease, dyslipidaemia may contribute to acute stroke in addition to coronavirus disease pathology


In the era of big data, the field of deep learning is developing rapidly. Deep learning model algorithms and a large amount of data make deep learning an effective tool to solve practical problems. However, in the current centralized deep learning model of a large number of client-server models, when we upload our data for training on the server side, there is a risk of leaking privacy. Federated Learning is a type of distributed machine learning that allows multiple institutions or individuals to learn collaboratively without exchanging data. Users only upload their model parameters, and the server aggregates the model parameters of each user into a global model and returns it to the client, and the client updates its local model according to the global model to achieve the global optimal solution, avoiding leakage of private data. However, attackers can still restore user data by obtaining uploaded model parameters from users, which leads to the fact that only transmitting model parameters cannot protect user privacy. Therefore, the issue of privacy protection has become the focus of federated learning. In this paper, the CSP (conjugate search problem) fully homomorphic encryption algorithm is used to encrypt the user model parameters. The CSP encrypt algorithm will not cause the loss of model performance, and at the same time has the characteristics of fast encryption speed, which is very suitable for application in the field of machine learning.


The advent of next generation sequencing technologies (NGS) has deeply transformed today's biology. Thanks to this new approach many areas of study have been developed and scientists have the ability to analyze nucleic acids of any biological entity. Metagenomics is one of the most recent and promising fields among NGS applications. It allows microbial community analysis within a specific environment in order to obtain knowledge on genomes and taxonomic composition of environmental microbes and entire microbial communities. In this context, the human microbiota, represented by the total ecological community of commensal, symbiotic, and pathogenic microorganisms coexisting in our bodies, is drawing research's attention as it plays a central role in maintaining healthy status or leading to disease conditions. Particularly, the human gut is colonized by thousands of different microbial species, of which several billions are bacteria involved in important functions: gut permeability, immune system development and activation. The aim of this project is to deeply analyze the gut microbiome composition, from duodenal biopsies of Crohn's disease and Celiac disease affected patients.


Human-AI collaborative decision-making has become a prevalent interaction paradigm, but the lack of transparency in AI algorithms presents challenges for humans to understand the decision-making process. Such lack of comprehension can lead to issues of over-reliance or under-reliance on AI recommendations. In this study, we focused on a human-AI collaborative income predicting task and investigated the influence of AI transparency and reliability on task performance. The results revealed that when AI reliability was high (75% and 90%), transparency had no significant effects on human decision-making. However, at a lower level of reliability (60%), higher transparency levels led to increased compliance with AI suggestions, thereby demonstrating a persuasive effect. Further analysis indicated that compliance rates only improved when AI made correct decisions, rather than when AI made incorrect ones. However, transparency did not significantly impact humans' ability to correctly reject erroneous recommendations from AI, suggesting that increasing transparency alone did not enhance humans' error detecting ability. In conclusion, when the reliability of AI is low, heightening transparency can promote appropriate dependence on AI without elevating the risk of over-reliance. Nevertheless, further research is necessary to explore effective strategies that can assist humans in identifying AI errors effectively.


10569Background: Survivors of childhood cancer experience an increasing incidence of late sequelae with age, with the effect on health likely compounded by limited physical activity and low cardior...


1. Sexual selection is a powerful evolutionary force that is hypothesised to play an important role in the evolution of lifespan. Here we test for the potential contribution of sexual selection to the rapid evolution of male lifespan in replicated laboratory populations of the seed beetle, Callosobruchus maculatus.


This report describes the method of introduction of amniotic membrane transplantation (AMT) in North Medical Center Kyoto Prefectural University of Medicine. The case involved a 70-year-old woman who underwent AMT for recurrent pterygium. 7 years earlier, she had undergone a surgical procedure for pterygium in her right eye. At 8 postoperative months, the pterygium recurred, and the lesion gradually progressed to the center of the cornea, 症 例 北部医療センター誌 Vol. 5-2019 59 resulting in a loss of visual acuity. In Japan, insurance has covered AMT treatment for refractory ocular surface diseases since 2014, but adequate facilities are not common in remote area, where our hospital is located. We took the necessary measures for certification, were given official approval to do AMTs, and performed the repeat pterygium surgery combined with AMT for her. At 1 postoperative month, her visual acuity had improved from 20/100 to 20/20, and at 3 postoperative months there was no recurrence of the pterygium. We were able to perform the AMT safely in remote area, and it effectively treated the recurrent pterygium. Keyword: recurrent pterygium, amniotic membrane transplantation, cornea


Back ground: WHO classification of salivary gland adenomas includes a morphological spectrum based on cellular and stromal components. Pure ductal adenoma is not a valid entity in the current WHO classification. Clinical data: A 73 year old woman underwent a parotidectomy with clinical suspicion of pleomorphic adenoma. On follow up at 32 months, there was no evidence of recurrence or metastasis. Pathological findings: Grossly a relatively circumscribed 22 mm tumour was identified. Histologically it was composed of ductal structures lined by columnar cells with eosinophilic cytoplasm and no cytological or architectural features of malignancy. The ducts showed a great resemblance to normal striated ducts. On immunohistochemistry the lesional cells exhibited an epithelial phenotype (positive for AE1/3, CK7, and CEA) and immunostains for myoepithelial markers failed to demonstrate a myoepithelial component. Electron microscopy attributed an epithelial nature to the tumour with ultrastructural features suggestive of intermediate ducts. Discussion: This case demonstrated features of a benign neoplasm, although difficult to subtype. Entities including pleomorphic adenoma, oncocytoma, basal cell and canalicular adenoma were considered in the differential diagnosis. On immunomorphological grounds, there was a great resemblance to striated ducts. A series (6 cases) of striated duct adenomas has been previously reported in the literature. The current tumour had an essential histological resemblance to those cases, although EM failed to prove a definite striated duct origin. Conclusion: We report a case of salivary gland neoplasm with ductal differentiation intermediate between striated and intercalated ducts. We believe pure ductal salivary gland adenomas are uncommon but do exist and should be considered in the differential diagnosis if appropriate morphological features are identified.


Definition The major characteristics of metabolic syndrome include insulin resistance, abdominal obesity, elevated blood pressure, and lipid abnormalities (i.e., elevated levels of triglycerides and low levels of high-density lipoprotein [HDL] cholesterol). Initially defined by an expert panel of the World Health Organization in 1998,5 the NCEP–ATP III4 has created an operational definition of metabolic syndrome: the co-occurrence of any three of the abnormalities mentioned above (Table 14,5). Metabolic syndrome is associated with a proinflammatory/prothrombotic state that may include elevated levels of C-reactive protein, endothelial dysfunction, hyperfibrinogenemia, increased platelet aggregation, increased levels of plasminogen activator inhibitor 1, elevated uric acid levels, microalbuminuria, and a shift toward small, dense particles of low-density lipoprotein (LDL) cholesterol. Insulin resistance also has been M etabolic syndrome, also called insulin resistance syndrome or syndrome X, is a cluster of risk factors that is responsible for much of the excess cardiovascular disease morbidity among overweight and obese patients and those persons with type 2 diabetes mellitus.1 Differences in body-fat distribution (i.e., gynecoid versus android) associated with an altered metabolic profile were documented in the medical literature 50 years ago. Given the name syndrome X in 1988,2 each component of the syndrome has been associated with an increased risk of cardiovascular disease.3 A report4 from the National Cholesterol Education Program– Adult Treatment Panel (NCEP–ATP III) identified metabolic syndrome as an The constellation of dyslipidemia (hypertriglyceridemia and low levels of high-density lipoprotein cholesterol), elevated blood pressure, impaired glucose tolerance, and central obesity is identified now as metabolic syndrome, also called syndrome X. Soon, metabolic syndrome will overtake cigarette smoking as the number one risk factor for heart disease among the U.S. population. The National Cholesterol Education Program–Adult Treatment Panel III has identified metabolic syndrome as an indication for vigorous lifestyle intervention. Effective interventions include diet, exercise, and judicious use of pharmacologic agents to address specific risk factors. Weight loss significantly improves all aspects of metabolic syndrome. Increasing physical activity and decreasing caloric intake by reducing portion sizes will improve metabolic syndrome abnormalities, even in the absence of weight loss. Specific dietary changes that are appropriate for addressing different aspects of the syndrome include reducing saturated fat intake to lower insulin resistance, reducing sodium intake to lower blood pressure, and reducing high-glycemic–index carbohydrate intake to lower triglyceride levels. A diet that includes more fruits, vegetables, whole grains, monounsaturated fats, and low-fat dairy products will benefit most patients with metabolic syndrome. Family physicians can be more effective in helping patients to change their lifestyle behaviors by assessing each patient for the presence of specific risk factors, clearly communicating these risk factors to patients, identifying appropriate interventions to address specific risks, and assisting patients in identifying barriers to behavior change. (Am Fam Physician 2004;69:2875-82,28878. Copyright© 2004 American Academy of Family Physicians.)


AMERICANS SEEM to have awoken to the dual epidemics of obesity and diabetes. Consumers are starting to read food labels more closely, schools are taking sugary drinks and snacks out of the lunchroom, and entire U.S. cities have gone on diets. Still, the incidence of type 2 diabetes, a by-product of obesity and the most common form of the disease, is growing by leaps and bounds. According to the Centers for Disease Control & Prevention, some 24 million Americans—about 8% of the country—have some form of diabetes, up by 3 million people in just two years. Another 57 million are labeled as "prediabetic." Type 2 diabetes occurs when the body starts losing its ability to respond to the insulin it produces. Because insulin is responsible for shuttling sugar to cells, glucose begins to accumulate in the bloodstream, depriving cells of energy and straining multiple organs. The disease can sometimes be controlled by diet and ...


Objective Discuss the nursing intervention programs in the first-stage revision surgery for total knee arthroplasty postoperative infection.Methods We collected 54 cases with infection after total knee arthroplasty from April 2005 to December 2012.The patients received the first-stage revision surgery to treat the postoperative infection.And then we worked out suitable nursing intervention programs for them.The nursing programs focused on disease observation,nursing on operation area and drainage tube,infection control,and personalized functional exercise.Results Among 54 patients who received the first-stage revision surgery and nursing intervention treatment perioperatively,52 cases recovered completely and were discharged from hospitals after 2 weeks.But 2 cases could not function well after the treatment,and the KSS score is 50 by average.The KSS score for the other 52 cases reached 94 on average.The patients′satisfaction with the treatment is up to 92.6%.Conclusion The nursing intervention programs in the first-stage revision surgery for total knee arthroplasty postoperative infection are effective and feasible and helpful in patients' maximum recovery.Patients are very satisfied with the result of treatment,nursing and recovery.


-sensor that triggers IGF-1 exocytosis inthese neurons. Deletion of Syt10 impaired activity-dependentIGF-1secretioninolfactorybulbneurons,resulting in smaller neurons and an overall decreasein synapse numbers. Exogenous IGF-1 completelyreversed the Syt10 knockout phenotype. Syt10 colo-calized with IGF-1 in somatodendritic vesicles ofolfactory bulb neurons, and Ca


In an operating high-temperature (1000{degrees}C) solid oxide fuel cell (SOFC), the interconnect separates the fuel (P(O{sub 2}){approx}10{sup -16} atm) and the oxidant (P(O2){approx}10{sup 0.2} atm), while being electrically conductive and connecting the cells in series. Such severe atmospheric and thermal demands greatly reduce the number of viable candidate materials. Only two materials, acceptor substituted lanthanum chromite and yttrium chromite, meet these severe requirements. In acceptor substituted chromites (Sr{sup 2+} or Ca{sup 2+} for La{sup 3+}), charge compensation is primarily electronic in oxidizing conditions (through the formation of Cr{sup 4+}). Under reducing conditions, ionic charge compensation becomes significant as the lattice becomes oxygen deficient. The formation of oxygen vacancies is accompanied by the reduction of Cr{sup 4+} ions to Cr{sup 3+} and a resultant lattice expansion. The lattice expansion observed in large chemical potential gradients is not desirable and has been found to result in greatly reduced mechanical strength.


During a thin film application, the surface of the coating liquid applied to the substrate becomes uneven because of the geometry of the substrate, viscosity of the coating liquid, surface tension, and its contact angle with the substrate. The surface is particularly uneven at the edge corner portion of the substrate and is thicker than the average coating thickness. This study used the volume-of-fluid (VOF) method to examine the surface unevenness of the coating liquid in terms of the contact angle of the substrate surface and sides. After the coating liquid was evenly applied to the substrate, the maximum height of the uneven region of the coating liquid at the edge of the substrate increased as time passed. The point of maximum height moved away from the edge corner portion of the substrate. The coating liquid applied to the substrate with a contact angle less than 90° exhibited a pinning effect in which the contact point was fixed at the edge. The surface unevenness was more pronounced in the absence of the pinning effect than in its presence, due to the effects of the viscosity of the coating fluid and the surface energy of the substrate.


We present a new polynomial-free prolongation scheme for Adaptive Mesh Refinement (AMR) simulations of compressible and incompressible computational fluid dynamics. The new method is constructed using a multi-dimensional kernel-based Gaussian Process (GP) prolongation model. The formulation for this scheme was inspired by the GP methods introduced by A. Reyes et al. (A New Class of High-Order Methods for Fluid Dynamics Simulation using Gaussian Process Modeling, Journal of Scientific Computing, 76 (2017), 443-480; A variable high-order shock-capturing finite difference method with GP-WENO, Journal of Computational Physics, 381 (2019), 189-217). In this paper, we extend the previous GP interpolations and reconstructions to a new GP-based AMR prolongation method that delivers a high-order accurate prolongation of data from coarse to fine grids on AMR grid hierarchies. In compressible flow simulations special care is necessary to handle shocks and discontinuities in a stable manner. To meet this, we utilize the shock handling strategy using the GP-based smoothness indicators developed in the previous GP work by A. Reyes et al. We demonstrate the efficacy of the GP-AMR method in a series of testsuite problems using the AMReX library, in which the GP-AMR method has been implemented.


After accumulating data on actual global temperature, I have come to notice that temperature increases suddenly occurred twice: at around 1910, then again around 1980. Interestingly, at around 1910 AC electricity use spread rapidly in industry, railways, and homes due to the use of large-scale hydroelectric AC power generation and long-distance highvoltage overhead transmission lines. Synchronism indicates that electricity was one of the causes of increasing global warming. It is demonstrated from both of a new circuit theory and supporting evidence that electromagnetic commonmode noise of the wave type propagates in the ground as an electric current, which is equivalently calculated by observed strength of magnetic field at the Earth's surface under overhead transmission lines. An inclusive amount of global Joule heating due to the ground current takes account of the total amount of electric power generation in the world. Water in the ground is vaporized by the Joule heating, and is converted to water vapor. Artificial continuous increase of water vapor in the atmosphere has enhanced global warming due to the greenhouse effect. In around 1980, after the oil crises, useful power inverters to energy saving became available. The frequency of noise increased from commercial cycles (50Hz or 60Hz) to higher ones (5kHz or more), and thus increases of Joule heating due to stronger skin effect are continuing to contribute to the production of global warming. Quantitative calculations concerning this process show a temperature increase that is near to observations.


In recent years, the capacity has increased and the volume has been limited in the power transformers. The stray losses of the tanks and structural parts cannot be ignored in the load loss. The tanks and the structural parts are complex structures. It is difficult for transformer manufacturers to use analytical methods to calculate stray losses for each component in the power transformers. If the stray loss distribution of the components can be estimated, it will help to optimize the power transformer's cost and performance. Therefore, this paper uses the finite element method to solve the stray loss of components in the time-varying magnetic field. At the same time, the core losses of the magnetic shielding are solved. In addition, the position of the tap is considered, and the proposed stray loss model has the temperature factor, which can improve the accuracy of the simulation results. Finally, the short circuit test experiment is carried out in the 350 MVA three-phase five-limb power transformer. The proposed models and material parameters are verified by the experimental results.


From the latter half of the last decade, there has been a growing interest in developing algorithms for automatically solving mathematical word problems (MWP). It is a challenging and unique task that demands blending surface level text pattern recognition with mathematical reasoning. In spite of extensive research, we are still miles away from building robust representations of elementary math word problems and effective solutions for the general task. In this paper, we critically examine the various models that have been developed for solving word problems, their pros and cons and the challenges ahead. In the last two years, a lot of deep learning models have recorded competing results on benchmark datasets, making a critical and conceptual analysis of literature highly useful at this juncture. We take a step back and analyse why, in spite of this abundance in scholarly interest, the predominantly used experiment and dataset designs continue to be a stumbling block. From the vantage point of having analyzed the literature closely, we also endeavour to provide a road-map for future math word problem research.


In recent decades there have been many disputes about the viability of Russian education. Supporters of radical changes argue that it is ineffective in the new conditions of the global transition to digital. Schools and universities are intimidated by a generation of "zetas" who "do not succumb" to standard approaches, spending most of their free time online, with clip thinking, inability to concentrate for a long time, and other difficulties and peculiarities. Opponents of digitalization are trying to protect teenagers from unlimited use of gadgets. There are discussions about how to use digital devices wisely and without harming their health. In the spring of 2020 the situation develops in such a way that the "harm" from the long-term communication of young people with gadgets becomes incomparable with the possibility of stopping the learning process. Educational institutions are urgently moving to work in a remote format. In the course of this situation, this is the only way out. The transition reveals many problems that, if possible, are solved during the process. It becomes obvious that it is impossible to use distance learning as the only possible format of work. What the future will be like depends on many factors. Will it remain universal with a sign of quality of traditional Russian education or will it undergo a radical transformation? Employers rely on creative employees who are efficient in multitasking and capable of continuous self-education throughout their lives. The concept of life-long learning continues to be a trend, without giving up its positions. The purpose of this article is to find out whether the new generation of young people is so different that all approaches of the traditional education system are broken down about their "armor". Or under the flag of Generation Z the idea of a radical transition to a completely new education is being promoted.


in the unfolding of American history, whose story is most important, who is telling the tale" (316). She discusses iconoclasm and countermemorials as symptomatic of anger, which she categorizes as "an especially performative affect" in memorials (325). Writing as a critic as well as a historian, Doss identifies memorials that she deems less successful, as well as those that she admires for their openness and instructive questioning of national agendas and terms. Unfortunately there are no colored plates and the black and white illustrations are too small, but her comprehensive bibliography and copious notes are a goldmine for those who wish to pursue further research in this area. Doss succeeds admirably in her ambitious goals of charting how public feeling affects, shapes and motivates representations of American history and memory, as well as self and national identity.


In many European countries, external as well as internal social, economic and political changes have brought about a marked need for professional training of managerial staff in education (Huber, 2003: 315). This article is one in a series that springs out of a British Council sponsored conference held in the Czech Republic in 2003, organized jointly by the Educational Management Centre of the Faculty of Education at Charles University, Prague and the Centre for Educational Leadership of the Faculty of Education at The University of Manchester. The article offers a comparative analysis of the leadership and management staff training patterns practised in the education sector in three European Union countries including: Finland, the Netherlands and


A 12-year-old boy developed a phototoxic rash with subsequent progression to Stevens-Johnson syndrome due to prophylactic ingestion of antimalarials (chloroquine and sulfadoxine-pyrimethamine; Fansidar). The patient recovered from his skin symptoms after 4 weeks during which he received systemic corticosteroids and antibiotics. This unusual combination of two different patterns of adverse cutaneous drug reactions was most probably caused by the sulfonamide component of Fansidar.


OBJECTIVE
This study determined the effect of n-3 PUFAs enriched hen eggs consumption on IgG and total plasma protein N-glycan profiles and inflammatory biomarkers level in healthy individuals (N = 33) and cardiovascular (CV) patients (N = 21).

MATERIALS AND METHODS
Subjects were divided to Control-Healthy and Control-CV subgroups (consumed three regular hens' eggs/daily (249 mg n-3 PUFAs/day)), and n-3-PUFAs-Healthy and n-3-PUFAs-CV subgroups (consumed three n-3 PUFAs enriched hen eggs/daily (1053 mg n-3 PUFAs/day)) for 3 weeks. Serum free fatty acids profile and high-sensitivity C reactive protein (hsCRP), interleukin 6 and 10 (IL-6, IL-10) and tumor necrosis factor alpha were measured. Total plasma protein and IgG N-glycome have been profiled before and after dietary protocols.

RESULTS
Serum n-3 PUFAs concentration significantly increased following n-3 PUFAs hen eggs consumption in both n-3-PUFAs-Healthy and n-3-PUFAs-CV. IL-10 significantly increased in both Healthy subgroups, while no change occurred in CV subgroups. Derived IgG N-glycan traits: bisecting GlcNAc (B) significantly decreased in n-3-PUFAs-Healthy, while agalactosylation (G0) and core fucosylation (CF) significantly increased in Control-Healthy. Derived total plasma protein N-glycan traits: high branching glycans (HB), trigalactosylation (G3), tetragalactosylation (G4), trisialylation (S3), tetrasialylation (S4) and antennary fucosylation (AF) significantly decreased, while G0, monogalactosylation (G1), neutral glycans (S0), B, CF and oligomannose structures (OM) significantly increased in n-3 PUFAs-CV. Digalactosylation (G2) significantly decreased, and G0, G1, S0, disialylation (S2), B and CF significantly increased in Control-CV.

CONCLUSIONS
n-3 PUFAs consumption alters IgG N-glycan traits and IL-10 in healthy individuals, and total plasma protein N-glycan traits in CV patients, by shifting them toward less inflammatory N-glycosylation profile.


The formation rates and energy yields of H2 formed from methanol, propanol, and ethanol solutions exposed to a nonthermal pulsed plasma-gliding arc reactor equipped with a spray nozzle were determined. The H2 energy yield formation was the highest with Ar carrier and pure methanol giving 176 ± 25% kW h at the highest liquid flow rate. This value is higher than other reported plasma technologies and within error of the energy yields for more conventional thermal reforming. Liquid droplets can enhance energy yield; however, the low chemical yields of H2 suggest the need for reactor operation with a recycle stream.


The response treatment of structural systems subject to stochastic loading requires the mathematical modeling of the input load, propagation such as input through the systems, and the treatment of uncertainty inherent in the output using probabilistic methods. For jack-up structures, the input load from the wave is modeled using the significant wave height and wave period which are statistical averages obtained from long term studies. The variability in the determination of these wave parameters leads to further uncertainty in the response output. This study, therefore, investigated the sensitivity of these wave parameters to the time-dependent reliability of jack-up. The wave was modeled using Karhunen-Loeve representation, and the propagation of uncertainty was performed on a simplified jack-up model using Duhamel convolution integral. The response analysis was performed using VanMarckes time-dependent solution method. The results of jack-up survival probability obtained for different failure criteria in deck displacement show that the probability is more sensitive to the wave period than the wave significant height.


In this paper, based on the scope, specification, definitions and requirements of the ISO 14000 series of enviromental management standards (EMS), a primary comparative study on the conservation and protection of fisheries resources and environment mangement in China has been carried out. The study will help creating the understanding of the tendency of fisheries management and related concepts of conventions and regulations in the world, and give comments on the fishery ecosystem protection of China,particularly emphasis the importance of species variation and the balance of ecosystem. The paper suggested that (1) The companies, corporations, firms, enterprises, and government authorities or institutions in China should establish and maintain procedures to make their employees or members at each level to create the awareness on the importance of fisheries resources conservation and environment protection. (2) The top manager (or management) of the organization should establish and define the organization's fisheries resources and environmental policy and related planning, which should be available to the public for the checking and monitoring. (3) To establish a records system, collecting the documents of all activities of fishing operation and relative processing and transportation, as evidences for checking and inspection. (4) To establish a "green mark" or "eco-labeling" system, and to establish the law or regulations for forbidding and preventing the fishing, selling and buying the undersize fishes and larvae from illegal catch. The eco-labeling program proposed in the FAO consultant meeting should be paid more attention, and related research work should be organized in the national level to meet the requirements of international fisheries management.


It is confirmed that the urban influence region is one of the important contents of researching the reciprocity between cities and regions.It also has a great significance to urban geography and urban planning.This paper selects indexes concerning about the city influence area,then utilizes PCA(Principal Component Analysis)and data transformation to quantify the influence power of cities in Beijing-Tianjin-Hebei Region finally,and calculates the urban influence area in virtue of the breakpoint theory and weighted Voronoi diagram.Because the previous methods for selecting regional central cities and dividing urban economic regions are not appropriate for analyzing local regions which contain megalopolis,this paper suggests dividing BeijingTianjin-Hebei Region by analyzing the relationship of grid in the weighted Voronoi diagram based on breakpoint theory.Finally Beijing-Tianjin-Hebei Region is divided into three urban economic regions with three central cities in the first rank and two central cities in the second rank,which provides a reference for urban planning and regional development in this region.


Fish cell line is an important biological resource with potential applications in several fields of life sciences. After the development of the first fish cell line (i.e. rainbow trout, Salmo gairdneri, gonadal cell line, named as RTG-2) by Wolf and Quimby in 1962, several fish cell lines have been developed. These cell lines became popular due to certain advantages over the traditional animal cell line models. Fish cell lines are being widely employed for numerous applications such as virus isolation, disease diagnosis, eco-toxicology, cytology, developmental biology and gene expression studies. Fish cell lines, being of poikilothermic origin, grow well at room temperature without thermo-regulated incubators, unlike mammalian cell lines. Moreover, the Leibovitz-15 (L-15) medium, used in fish cell lines, does not require CO2 buffering action, thus CO2 incubators are not strictly necessary and the cells can grow in BOD incubators itself. In recent years, changing aquaculture practices has made fish cell culture an important tool for researchers. Lakra et al. listed 283 fish cell lines developed across the world encompassing both marine and freshwater species. But maintenance and storage of cell lines are as important as developing the cell line. If proper care and checks are not maintained, it is possible that the cell lines may be lost due to natural senescence, contamination, breakage, electrical or equipment failure, etc. Possibility of loss of cell lines may also occur due to unforeseen natural calamities such as floods and earthquakes. Hence, it is imperative that these valuable cell lines need to be stored at multiple places, in addition to the developer's lab. This is where the concept of a repository becomes essential. Depositing a cell line in a repository not only provides recognition to the developer, but also enables other researchers to obtain and use the cell lines preventing duplication of work. American Type Culture Collection (ATCC), European Collections of Cell Cultures (ECACC), German Collection of Microorganisms and Cell Cultures (DSMZ), RIKEN (Japan) and CellBank (Australia) are the major repositories in the world with large collections of human, animal, microbial, hybridomas, etc., but few fish cell lines are also being maintained by them. The National Centre for Cell Sciences (NCCS), Pune, is one of the most popular and trusted cell line repositories in India, but it is maintaining very few fish cell lines. Since only a few fish cell lines were available with popular repositories, the National Repository of Fish Cell Lines (NRFC) was established in 2010 at ICAR-NBFGR, Lucknow, with financial support from DBT, to accelerate fish cell culture research. At present NRFC (http://mail.nbfgr.res.in/nrfc/) with 63 fish cell line accessions, is one of the largest collections of authenticated fish cell lines in the world (Figure 1). Of these, 28 cell lines were developed, characterized and deposited by ICARNBFGR and the rest were deposited by other researchers across India. Fish cell lines can be used in a variety of applications. The most widely used applications are in virology, toxicology and cytological studies. The institute is regularly employing cell lines to determine inhibition constant (IC50) values of toxicants such as like heavy metals (mercury, cadmium, arsenic, chromium), pesticides (pethoxamid, tembotrione) and other chemicals/pollutants. The institute has worked extensively on studying susceptibility of the fish cell lines to the viruses such as viral nervous necrosis virus (VVNV), cyprinid herpesviral haematopoietic necrosis virus (CyHv‐2), tilapia lake virus (TiLV), etc. and also on the cytotoxic effects of extracellular components from various bacteria using cell lines. Bureau is also actively working on developing new cell lines of fish species with potential aquaculture upscaling. The institute is planning to develop cell-specific lines, like hepatocytes, etc., in the future. Germplasm conservation is a complex subject that requires a combination of scientific research, effective management strategies and coordination among various implanting agencies to achieve upright results. Cell lines act as a tool for ex situ germplasm conservation. Stem cell lines/induced pluripotent stem cells (iPSCs) can support conservation programmes. All the authenticated and available cell lines in the repository have been stored at ultra-low temperature of –196°C in LN2 for future use. NRFC has six cell line accessions of fishes that are vulnerable, endangered and near threatened according to IUCN Red List categories. It is expected that in the years to come, when the success rate of cloning improves, the availability of cell lines of endangered species can help in conservation strategy.


Synapse formation is a complex process requiring a high degree of coordination between presynaptic and postsynaptic cells. Speed and reliability of synaptic transmission demand that the appropriate neurotransmitter receptors be highly concentrated in the postsynaptic membrane precisely beneath transmitter release sites in the presynaptic cell. In the central nervous system, a single neuron may receive thousands of synaptic contacts from other neurons releasing a variety of neurotransmitters. Thus, neurons must possess the ability not only to cluster, but also to sort, the proper transmitter receptors to the correct synaptic site. Understanding, on a molecular level, how such specializations develop is a major goal of neurobiological research. This commentary will focus on the synaptic clustering and anchoring of neurotransmitter receptors through their association with a variety of cytoplasmic proteins.


Two multi-step models for the pushover analysis of in-plane loaded historical masonry walls with irregular texture are presented. Both approaches are developed within an equivalent frame assumption. The first three-step model is a heuristic homogenization procedure in which the first step masonry is substituted with a macroscopic equivalent homogeneous material, with ultimate properties deduced from the solution of suitable boundary value problems on sample windows with different sizes. Masonry strength domains are evaluated through a limit analysis upper bound finite element (FE) approach. In the second step, ultimate bending moment-shear force strength domains of piers and spandrels are derived by means of a homogeneous upper bound FE limit analysis. In the last step, a frame model of an entire wall is assembled, where piers and spandrels are modeled as elastic-plastic Timoshenko beams with ultimate resistance evaluated using previous steps. The second approach is a two-step heterogeneous model, where piers and spandrels are analyzed through a FE limit analysis model, discretizing the walls "as they are". To validate both approaches, a masonry wall arranged in irregular texture is studied in the inelastic range under increasing static loads. Results are compared with those obtained by a standard frame model and an expensive heterogeneous 2D FEM.


Objective: To study the Chinese and western medicine treatment of diabetic osteoporosis, for hospitals to improve the treatment level of diabetic osteoporosis to provide relevant reference.Method: 70 cases of diabetic osteoporosis patients were selected in our hospital from October 2011 to December 2013, the patients were divided into two groups according to random number table method, each group had 35 cases, the control group was used Allen phosphonic acid sodium treatment, and on this basis, the observation group was given sugar pulse treatment. After treatment, the clinical treatment of two groups were analyzed and compared. Result: After treatment for 6 months, the bone mineral density value of the observation group was(0.841±0.017)g/cm2, and compared with(0.731±0.028)g/cm2 beforetreatment and the control group's(0.768±0.011)g/cm2, the differences were statistically significant(P0.05). At the same time, in the aspect of clinical curative effect, 21 cases were markedly effective, 13 cases were effective in the observation group, the total effective rate was 97.14%, obviously better than the control group of 77.14%, the difference was statistically significant(P0.05). Conclusion: Integrated traditional Chinese and western medicine therapy in patients with diabetic osteoporosis, can effectively improve the level of clinical treatment, the patients with bone mineral density situation improved, and the safe, reliable, relatively high clinical value, worthy of further promotion.


During general anaesthesia without any volatile anaesthetic agents, ten infants and ten children received incremental doses of vecuronium to achieve a 95% neuromuscular block. Thereafter, the thenar electromyographic response was allowed to recover spontaneously. Total dose of vecuronium to establish a 95.0 ± 0.5% (mean ± SEM) neuromuscular block was 66% greater for children than for infants (73 ± 4 vs. 44 ± 4 μg·kg−1, P < 0.0001). However, recovery index and time to complete recovery of the neuromuscular function were 88 and 89% longer, respectively, in infants than in children (P < 0.0001). These results of the effect of an equipotent dose of vecuronium in infants and in children confirm that vecuronium is a long acting neuromuscular blocking agent in infants.


The invention relates to a raffinoses oligosaccharide with stachyose as main materials and method for preparation, wherein the raw material includes glutinous rehmannia, artichoke betony, and ground bamboo, the product contains total sugar >96%, wherein the content of stachyose is over 62-71%, the content of raffinose family functional oligosaccharide (mainly stachyose) is 75-90%. The production technique consists of clarifying and decolouring the raffinate with chitosan and activated charcoal, and carrying out desalinization with 1-4 sets of ion-exchange resins.


A generalized version of Takane and Carroll's (1981) (Psychometrika, 46, 389–405) scaling model is developed to analyze rank order data. This model assigns to each stimulus n (the number of stimuli) different scale values each of which is to be utilized at its respective occasion of successive first choice in the ranking task. The n scale values assigned to a stimulus is predicted by using the cumulative binominal distribution function for an assumed set of n−1 Bernoulli trials of a simple judgment about the same attribute of that stimulus as is to be scaled from the ranking data. Examples of the application of the model are reported. They have demonstrated that the generalized model can account for all the data sets examined better than the original one.


1. Animal communities are essential drivers of energy and elemental flow in ecosys ‐ tems. However, few studies have investigated the functional role of animals as sources of dissolved organic matter (DOM) and the subsequent utilization of that DOM by the microbial community. 2. In a small forested headwater stream, we tested the effects of taxonomy, feeding traits, and body size on the quality and quantity of dissolved organic carbon (DOC) and dissolved


This research, with data collected pre-COVID-19, provides insight into an interesting and rarely studied event, the young adult (YA) literature festival. Survey research conducted at a YA festival, with attendees generally from middle school through university age, provided useful insight into the motivations for visiting the festival, determination of the person making the decision to attend (surprisingly, the YA and rarely his/her parent) and the satisfaction and dissatisfaction factors that affected the attendee's attitude toward the festival. In addition, Significance Performance Analysis (SPA) is introduced as an alternative to the widely used Importance Performance Analysis (IPA) model.


"Monodispersed Metal (Hydrous). Oxides A Fascinating Field of Colloid Science', Matijevic, Acc. Chem. Res., 1981, pp. 22-29. Formation, Packing, and Sintering of Monodisperse TiO, Powders, Barringer et al., J. Am Ceram. Soc. 1982, pp. C199-C201. "Applications of Sol-Gel Methods for Glass and Ceramics Process ing'. Mackenzie, Ultrastructure Processing of Ceramics, Glasses and Composites, 1984, pp. 15-26. "Synthesis and Characterization of Monosized Doped TiO, Pow ders". Fegley Jr. et al., J. Am. Ceram. Soc. 1984, pp. C113-C116. "Preparation of Y-Doped Zirconia by Emulsion Technique', Rinnet al., Ceramic Powder Processing Science (Proceedings of the Second International Conference, Oct. 12-14, 1988, pp. 221-228. "Herstellung Nanoskaliger Pulver Durch Thermische Synthese im Pulsationsreaktor'. Begand et al., 1988, D-12-D-16. "Einsatz des Pulsationsreaktors für die Stoffbehandlung in der Chemischen Industrie'. Begand et al., 1988, pp. 746-749. "Preparation of Monodisperse Ar0 by the Microwave Heating of Zirconyl Chloride Solutions'. Moon et al., J. Am. Ceram. Soc. 784), 1995, pp. 1103-1 106. "Synthesis, Characterization, and Processing of Monosized Ceramic Powders". Fegley et al., Mat. Res. Soc. Symp. Proc. vol. 32, 1984, pp. 187-197.


Radial-inflow turbines (RI turbines) are critical components of air cycle machines (ACM), utilized in environment conditioning systems (ECS). In this work, a process is presented for the full design of a radial-inflow turbine, including volute, nozzle blade row and rotor blade row. The preliminary and detailed aerodynamic design approaches are explained in detail. A mean-line (1D) analysis method coupled with the preliminary design is employed to evaluate the aerodynamic performance of the RI turbine. Then, ANSYS CFX is used to perform unsteady 3D simulations of the designed RI turbine at design and off-design conditions to predict the aerodynamic performance of the turbine for future optimization.


The innovative combination of sonochemistry (power ultrasound) and photocatalysis (UV light) has been extensively investigated in the literature, especially as an advanced oxidation process. Based on these results but with a completely different strategy, the sonophotocatalysis starts to be applied to organic reactions and could represent an innovative way to valorize biomass into fuels or platform molecules. This article discusses this opportunity and proposes some trends and outlooks for further researches in the area.


Abstract
Finnish MoD has stated that the price of modern defence equipment is estimated to double in every seven years. The article separates conceptually price increases as measured by price indexes and unit price escalation, as seen by the buyer. The former is not found to increase at a rate higher than general inflation. The latter, based on several empirical studies, is found to increase at rate exceeding inflation. The rate is found to vary between classes of equipment. The explanation for this in the literature is technological change together with performance competition with adversaries. A case study with XA armoured personnel carrier is presented with the aim of bridging the viewpoints of price indexes and buyer. It is also shown in the case that indeed a rational buyer can make equipment selection choices that result in high unit price increase rate. In the end, the relevance of unit price increase and its consequences to a small nation is discussed.


A novel method based on Monte Carlo simulation was presented for analysis of signal processing performance degeneration of linear frequency modulation(LFM) seeker radar in the radiation of high power microwave(HPM).The influence of HPM on the seeker radar was modeled as equivalent noise random process called equivalent noise process model.According to the signal processing of LFM radar,the radar signal processing performance figures,such as target radar echo integration efficiency,range resolution,velocity resolution and angle measuring precision etc,were theoretically analyzed under HPM radiation interference.The simulations reveal that serious performance degeneration was caused by the strength of equivalent noise process and the amplitude-phase's noise correlation.


The invention relates to a purification device for dioxin sample pretreatment, in particular to a gas chromatogram (GC) separation and liquid chromatogram (LC) purification on-line combined dioxin sample purification device. The device consists of a high pressure pump, a sample valve, a six-way switching valve, a retention gap column, a GC analysis column, a box body provided with a heating element and an exhaust fan, a four-way valve provided with a heating element, an LC column and the like. According to the device, a sample of big volume is introduced into the gas chromatogram by adopting a loop sample injection technology and the retention gap column, the semi-volatile component of a target is separated by the gas chromatogram, the target component is transferred to the liquid chromatogram and purified, and the friction of the target dioxin compound is selectively collected so as to finish automatic purification of the dioxin sample. The device for purifying the dioxin sample has the advantages of low solvent consumption, simple purification step, high analysis speed, low experiment cost, low health hazard and the like. The device has the same purification effect on other semi-volatile organic pollutants by proper condition change and optimization, and is suitable for separation and analysis of trace semi-volatile durable organic pollutants.


We have in the present study examined the properties and subcellular distribution of cholesterol ester metabolizing enzymes in human brain, and compared the levels of these enzymes in brains from patients with phenylketonuria (PKU), metachromatic leucodystrophy (MLD), and Down's Syndrome (DS).


OBJECTIVE To analyze the influence factors of the influenza like case(ILC)collected from sentinel point hospitals for surveillance ILC in 2010 in Chengdu,so as to improve the influenza virus separation rate of samples.METHODS The data on collected technique of ILC sample from six sentinel point hospitals were gathered and analyzed at the collected time and delivered time to influenza laboratory by statistics method.RESULTS The results showed that the samples qualified rate was low.Only the samples collected by two sentinel hospitals were up to standard.The majority samples collected by the other four hospitals were lower to standard.There were many questions on ILC sample collected time after ILC illness,and the delivery time to the influenza laboratory was collected by the sentinel hospitals.CONCLUSION The ILC collected time and the deliver time to the influenza laboratory needed improvement and the influenza virus isolated rate would be raised effectively.


The rapid development of GNSS, GNSS receivers of geodetic accuracy class, and inertial measurement units is offering a great opportunity to improve the applicability, productivity and user experience of high-precision RTK positioning. Benefiting from the tilt compensation technology, RTK positioning using a GNSS receiver can be used in difficult situations with increased speed and efficiency. In the article application of an inertial system for compensation of the marker tilt in GNSS receivers using Leica GS18 T as an example is considered, appropriate conclusions are made.


A research was conducted in thirty approximately 100 sq.m earthern ponds of the Brackishwater Aquaculture Centre (BAC), College of Fisheries, University of the Philippines, Leganes Iloilo from November 7, 1982 to March 7, 1983 to evaluate the effects of nine supplemental feeds containing different protein: energy ratios on the growth and survival of Tilapia nilotica in brackishwater ponds. Nine supplemental feeds formulated were with protein levels of 20%, 25%, and 30% each at three energy levels of 3,000 kcals; 3,500 kcals; and 4,000 kcals. There was a control treatment with no feeding so that mean weight gain growth rate, feed conversion rate, and survival were determined. Fish fingerlings were acclimated from 0-29 ppt. salinity before the experiment and 20% of fish in each treatment were sampled after every 30 days. Growth rates were significantly different and increased with increasing energy level at the 30% protein feeds but decreased at high energy levels in the 20% and 25% protein feeds. Feed conversion was significantly different due to interaction between protein and energy levels in the feeds, and was better at the 30:3,500 kcals feeds having a feed conversion of 1.55 g. Survival was not significantly different


The utility model relates to a waterproof and moisture-proof safe, comprising a safe body (1) the front side of which is provided with a doorframe (2), a door plank (3) which is matched with the doorframe (2) and rotatablely assembled at one side of the doorframe (2), a latch (4) which is arranged at the back surface of the door plank (3) and a drive structure (5) which is arranged on the door plank (3) to drive the latch (4) to move; a sealing strip (6) which can closely contact with the edge of the rear surface of the door plank (3) is fixed around the doorframe (2). The sealing strip (6) is an elastic sealing strip and the head of the latch (4) is smallish. The part of the latch (4) head which can contact with an inside end (21) of the doorframe (2) is a slant (41). The tilt direction of the slant (41) is that: the slant is gradually away from the inside end (21) of the doorframe (2) from an inner end (412) to an outer end (411). In the process of gradual locking of the latch, the door plank is driven to compress the sealing strip. The sealing strip is compressed and deformed by the door plank in a state of complete locking, thus effectively ensuring sealing performance between the doorframe and the door plank.


isons of sudden deaths.9 The fish oil fatty acids possess other protective characteristics: arterial function (vasodilatation) is improved, thrombogenic and inflammatory processes in the arterial wall are reduced, plasma triglycerides are lowered and HDL raised, and blood pressure may be lowered.10 Similarly strong evidence for the plant omega-3 fatty acid is lacking, although one secondary prevention trial, the Lyon Heart Study,11 provides encouragement for increased consumption of -linolenic acid from oils such as canola, flax and soy. Several prospective cohort trials also indicate that the consumption of -linolenic acid is linked to less CHD.1 In humans, the conversion of -linolenic acid into the long-chain EPA and DHA is not efficient, and the fish oil fatty acids need to be also eaten in larger quantities, probably as two fish meals weekly.


Information and details about requesting Interlibrary Loans. How to double checking if a needed article or book is already in the collection


The invention relates to a method for preparing a high-performance titanium and silicon molecular sieve. The method comprises the following steps of: 1) uniformly mixing tetrapropylammonium bromide, ammonium fluoride, water and a hydrogen peroxide solution to obtain a clarified solution A; 2) under the condition of stirring, adding a titanium source into the solution A, adjusting the pH to be 10 to 13 by using ammonia water, and ageing until a light yellow clarified solution B is formed; 3) adding a silicon source into the solution B, and uniformly mixing to obtain crystallized mother liquor C; and 4) crystallizing the crystallized mother liquor C at the temperature of between 130 and 190 DEG C and self-generated pressure for 10 to 100 hours, and separating to obtain the solid titanium and silicon molecular sieve product. According to the method, the problems of high production cost and low catalysis performance of the titanium molecular sieve in the prior art are well solved; and the method for assisting in synthesizing the titanium and silicon molecular sieve by using low-water-ratio ammonium fluoride can be applied to industrial production of the titanium and silicon molecular sieve.


Secukinumab is a monoclonal antibody targeting interleukin-17A and is commonly used for managing autoimmune diseases such as, psoriasis, psoriatic arthritis, and ankylosing spondylitis. Prior studies have suggested that anti-IL17 therapy may worsen symptoms in patients with pre-existing inflammatory bowel disease (IBD). However, it remains unclear if secukinumab is associated with new-onset IBD or in provoking a flare of previously quiescent IBD.

 We evaluated patients referred to our IBD clinic who developed intestinal inflammation after starting secukinumab for the management of autoimmune diseases.

 We performed a retrospective, observational study at a single tertiary care center between 2017 and 2020. Patients referred to our IBD clinic who developed intestinal inflammation after starting secukinumab were included. We excluded patients with an established pre-existing diagnosis of IBD and patients who had positive stool testing for infectious organisms. Patient demographics, disease characteristics, distribution of intestinal inflammation and clinical outcomes were assessed. The pathology slides were reinterpreted by a single pathologist with a specialty in gastroenterology to determine the histologic characteristics of the inflammation.

 A total of 8 patients developed gastrointestinal symptoms after starting secukinumab: 4 (50%) males with a median age of 42.5 (IQR: 35–50 years old). Secukinumab was initiated for psoriasis in 3 (37.5%) patients, psoriatic arthritis in 2 (25%) patients, ankylosing spondylitis in 2 (25%) patients and juvenile idiopathic arthritis in 1 (12.5%) patient. The median time of onset for gastrointestinal symptoms after starting secukinumab was 7 months (IQR: 4–15 months). Of the patients who underwent testing for inflammatory biomarkers, the median CRP was 25.5 (IQR 25.4–34.2). Endoscopic disease distribution involved the colon in 5 (62.5%) patients and the ileum and colon in 3 (37.5%) patients. In this series of patients, the histologic characteristics demonstrated three patterns of colitis: IBD-like (ulcerative colitis or Crohn's disease) in 6 (75%) patients based on mucosal granulomas and/or chronic inflammatory changes, MMF-like histology in 1 (12.5%) patient, characterized by an abundance of intraepithelial eosinophils in the lamina propria and numerous crypt apoptotic bodies, and finally active colitis in 1 (12.5%) patient characterized by an absence of chronic mucosal injury or granulomas. The treatment for these patients was cessation of secukinumab and initiating alternative therapies with close clinical monitoring.

 In this small case series, Secukinumab was temporally associated with the development of gastrointestinal inflammation. Further larger studies are required to confirm this association and to determine if IL-17 contributes to the pathogenesis of IBD.

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In order to improve the testing quality and make it normal,standard and scientific,it is necessary to establish a testing bank that is suitable for average college students.To begin with its purpose and significance,the rules,approaches,measures and procedures are discussed elaborately in this paper.


Purpose This article aims to illuminate the process and results of an international consortium project that considered terms and diagnostic criteria used in the identification of children with lang...


Leontief system of input-output analysis deserves to be studied as one of the most interesting problems of econornic theory and econometrics in the sense that it deals with the statistical application of the Walrasion economic equilibrium theory, although its theoretical scheme is rather simple. Quite recently. in Japan the studies in this line have been much in vogue among younger scholars and the government.1 The present writer tries to find out a theoretical ground, both for the substitutional relationships between the factors of production the problems of which were discussed by N. Georgescu-Roegen,2 P. A. Samuelsonf and others, and for the consistent numerical determination of input coefiicients with the production function itself. At the same time he introduces the maximization principle in this system,~ which could attach some meaning to the idea that we make use of this system as that of planned economy or that of economic prediction.


A chief goal of systems neuroscience is to understand how the brain encodes information in our visual environments. Understanding that neural code is crucial to explaining how visual content is transformed via subsequent semantic representations to enable intelligent behavior. Although the visual code is not static, this reality is often obscured in voxel-wise encoding models of BOLD signals due to fMRI's poor temporal resolution. We leveraged the high temporal resolution of EEG to develop an encoding technique based in state-space theory. This approach maps neural signals to each pixel within a given image and reveals location-specific transformations of the visual code, providing a spatiotemporal signature for the image at each electrode. This technique offers a spatiotemporal visualization of the evolution of the neural code of visual information thought impossible to obtain from EEG and promises to provide insight into how visual meaning is developed through dynamic feedforward and recurrent processes.


The utility model belongs to the technical field of the joint robot, in particular to a cable-driven multi-joint robot. The cable-driven multi-joint robot solves the problems of the multi-joint wirerope drive and arrangement. The cable-driven multi-joint robot comprises a hand, a wrist, a forearm, an upper arm, a shoulder, a waist and a base. The base is provided with the waist and the waist is connected with the shoulder through a crank shaft group. The shoulder is connected with the upper arm through a rotary joint shaft, wherein the upper arm is connected with the forearm through a driven gear II on a rotary joint shaft, the forearm is connected with the wrist through a driven gear I on a rotary joint shaft and the wrist is connected with the hand through a rotary joint shaft. Accordingly, multiple joints are formed at each interconnected portions. A multi-joint cable-driven unit is connected with one or more than two of the waist, the shoulder, the upper arm, the forearm, the wrist and the hand through soft ropes to form the cable-driven multi-joint robot. The cable-driven multi-joint robot has eight degrees of freedom and can give full play to advantages of wirerope drive, such as high drive accuracy and simple arrangement.


Worldwide tourism has been able to be a one of the important factors with respect to economic growth. Tourism is being seen as an opportunity for the economic growth of developing economies as its demand is still growing. Over the years tourism mediation has experienced major changes, including the arrival of the Internet and the application of Information and Communication Technologies (ICTs). This paper will investigates the ICT and tourism-led growth hypothesis in the case of India and Thailand by employing the cointegration, error correction models, and Granger causality tests using annual data for the last two decades. Major focus is to test the existence of the long-term equilibrium relationship between international tourism, ICT, and economic growth. Once a relationship is identified then the direction of the relationship was studied. In this research work, we have observed that economic growth in Thailand is led by tourism and ICT, but in the Indian economy, it seems that tourism is led by economic growth, and we are not able to transform our strength in ICT to the expected level. Study also concentrates on suggesting a model where tourism can be made a leading factor to influence GDP through optimum use of ICT.


A viscoplastic deformation damage model developed for RAFM steels in the reference un-irradiated state was modified taking into account the irradiation influence. The modification mainly consisted in adding an irradiation hardening variable with an appropriate evolution equation including irradiation dose driven terms as well as inelastic deformation and thermal recovery terms. With this approach, the majority of the material and temperature dependent model parameters are no longer dependent on the irradiation dose and only few parameters need to be determined by applying the model to RAFM steels in the irradiated state. The modified model is applied to describe the behavior of the RAFM steels, EUROFER 97 and F82H mod, observed in post irradiation examinations among others of the irradiation programs ARBOR 1 and ARBOR 2. Thereby tensile and low cycle fatigue tests are considered determining the material and temperature dependent parameters of the model and verifying its prediction capability.


The Amazon floodplains cover approximately 10% of the Amazon Basin and are composed of predominantly anoxic sediments that may store large amounts of carbon. Our study combines 210Pb derived sedimentation rates from four recently analyzed sediment cores (n = 4) with previously published organic carbon (OC) burial estimates (n = 18) to provide a broad, first order estimate of carbon accumulation in Amazon floodplain lakes. The OC burial rates were 266 ± 57 g C m−2 yr−1. This rate is several folds greater than those reported for lakes in arctic, boreal, temperate, and tropical regions. The large amount and spatial variation of OC burial rates in these floodplain lakes highlights the need for increased sampling efforts to better measure these potentially important components of the Amazon Basin carbon budget.


As an effective complement to the traditional centralized energy,Distributed energy has many characteristics,such as energy saving,efficient,environmentally friendly,safe and reliable.Greatly developing distributed energy was important for China to speed up the energy structure adjustment and achieve National 12th Five-Year energy-saving emission reduction targets.This paper introduced and analyzed foreign experience in the development of distributed energy,suggest corresponding development countermeasures from many aspects like policy,standards,techniques and plans under the present situation in China.


To study overwash thresholds on gravel barriers a laboratory experiment was undertaken in the Delta Flume (The Netherlands). Tests were made with variable wave heights and periods and increasing tidal levels. Current overwash prediction methods rely in the comparison between barrier crest elevation and the run-up level. More than ten run-up formulae were tested. Results showed that coastal hazards prediction related to overwash is a topic that needs further research.


Airbnb's structure, design, and algorithm create a website architecture that allows user discrimination to prevent minority hosts from realizing the same economic benefits from short-term rental platforms as white hosts, a phenomenon this Article refers to as 'redliking.' For hosts with an extra couch, spare room, or unused home, Airbnb provides an opportunity to create new income streams and increase wealth. Airbnb encourages prospective guests to view host photographs and personal information when considering potential accommodations, thereby inviting bias, both implicit and overt, to permeate transactions. This bias has financial consequences. Empirical research on host earning rates found that white hosts earn significantly more than their minority counterparts, even when controlling for location, size, and amenities. Airbnb's algorithm augments the effects and propensity of individual user bias, creating a system wherein race neutral variables serve as proxies for discrimination. Contemporary redliking parallels historic inequality related to housing wealth. In the early twentieth century, redlining maps were used to justify withholding investments from Black communities. Today, redliking continues the practice of directing wealth to white communities, reinforces systemic real property barriers by depriving minority hosts of important revenue streams, and exacerbates the racial wealth gap.

This Article examines the liability of websites like Airbnb for discrimination experienced by minority short-term rental hosts. The ability of anti-discrimination laws originally enacted to abolish redlining and protect minority consumers to combat redliking is complicated by the fact that sites like Airbnb serve multiple purposes; while guests use the platform to identify and book lodging, hosts use the site to advertise available accommodations. Looking to judicial interpretation of online speech and platform operator liability, this Article proposes two approaches – a general function test and a fragmented function test – to determine website liability for discrimination against short-term rental hosts. Noting the limitations of the existing anti-discrimination legal framework, this Article argues that eradicating redliking requires incorporating lessons on platform design from behavioral economics as well as eliminating opportunities for website algorithms to amplify and operationalize user discrimination.


Gnesippus is one of those characters we would gladly know more about. All the ancient evidence about him, deriving entirely from Athenian comedy, is given by Athenaeus (14.638D), who in turn may depend on an earlier, probably Hellenistic, treatise πεσ λψνψιδοφν ξψξ. Athenaeus may have known almost nothing else about him; certainly the phrasing of his introduction to the fragments (Ηξθτ πποφ υιξ Κ νξθνοξε ει λυμ ) does not inspire confidence. Davidson has recently argued that Gnesippus was not, as has been generally assumed, a tragic, lyric, or comic poet, but a writer of a sort of lyrical mime called πα ηξιοξ.1 He suggests that this was a form of sympotic entertainment largely performed by female slaves, and that we have a dramatic representation of such a mime in the lyric dialogue between the Old Woman and the Girl at Ar. Eccl. 877ff. There is no doubt that sympotic performances could include mimic elements, at least in the fifth century; Davidson (p. 49) rightly adduces the erotic pantomimic ballet depicting the love of Ariadne and Dionysus at Xen. Symp. 9.2–7. But his arguments raise numerous problems, and the evidence merits further consideration. Athenaeus refers to Gnesippus as παιηξιαησ0ζοΚ (though we might instead expect παιηξιοif a specific genre is meant) υ Κ μασ8Κ νο τθΚ, a description that may either be his own or one taken over from his source. The neuter πα ηξιοξ (pl. πα ηξια) and the connected feminine παιηξ α (Ionic -θ) are related to the verb πα ψ, the core meaning of which is 'play'. It is not in doubt that πα ψ and πα ηξιοξ could be used of mimetic or dramatic performances as early as the fifth century; neither, however, is restricted to this context. Plato (Leg. 7.796B) mentions the Λοφσ υψξ ξ πμια πα ηξια, apparently a type of ritual armed dance,2 and can disparagingly describe comedy as πα ηξια (Leg. 7.816E !τα ν"ξ ο#ξ πεσ η μψυ0 τυιξ πα ηξια! 7 δ% λψνψιδ αξ π0ξυεΚ μ ηονεξ). But it is the latter passage that is the more instructive: a πα ηξιοξ is essentially a light-hearted affair, and thus Gorgias can happily describe his Helen as one (ch. 21), where we might best translate jeu d'esprit. Such is no doubt also the significance to be attached to the Suda's statement that πα ηξια were written by Thrasymachus of Chalcedon.3 Related to this may be a fragment of Aristophanes which mentions someone putting on & ναυ0 υε λον'1 λα πα ηξια (fr. 7194). Davidson suggests that this could refer to putting on mimic pieces, but although the verb ( ξδειλξ ξαι) can be used in this way, the juxtaposition of πα ηξια with & ναυα is Classical Quarterly 53.2 608–639 (2003) Printed in Great Britain 608


Poster: "2017 ASM / R-0106 / Protect your neck – What every radiologist should know about the clearance of cervical spinal column injury" by: "J. Gajera1, A. Singh2; 1VIC/AU, 2QLD/AU"


Several factors are released in the liver microenvironment immediately after injury. Among these factors TNF alpha is implicated as a regulator of hepatocyte proliferation. Hepatocytes in the intact liver are mostly in the G0 phase of the cell cycle and after injury (including collagenase perfusion) display a constitutive expression of the growth-regulated c-myc oncogene. TNF alpha co-added with dHGF in hepatocyte cultures, superinduced the DNA synthetic response observed at all time points. In parallel, TNF alpha/dHGF-treated hepatocytes have shown increased expression of the c-myc oncogene at times corresponding to the in vitro G1 phase of the cell cycle. TNF alpha activated PLA2 in hepatocytes and it is believed that the subsequent production of PGE2 plays a role in the "priming" process in these cells and at the same time amplifies the proliferating signals induced by hepatocyte-specific growth factors.


According to the regional development characteristics and environmental impact assessment,the assessment index system consisted of economy,society and environment was constructed by using fuzzy analytic hierarchy process.The weight of each index was determined.A comprehensive evaluation was made by using the synthetic evaluation method in fuzzy mathematics.It is operable,simple and quantitative.Taking Chizhou Economic Development Zone for an example,the comprehensive evaluation was made on the evaluation model.The results showed that the sustainable development of Chizhou Economic Development Zone was in the middle state.Additionally,the results provided some theoretical basis for the formulation of the regional development and planning and the regional environmental management.


This essay bases its discussion on the current situation o f examination and evaluation of network information retrieval lesson.It expounds the contents,principles of examination online,especially the examination mode a nd the strategies to problems.


To investigate possible sources of the low-latitude midnight temperature maximum (MTM), a series of simulations was made with the National Center for Atmospheric Research thermosphere/ionosphere/electrodynamic general circulation model (TIEGCM). The MTM is a tidal phenomenon and thus is ultimately due to the thermospheric tidal sources: in situ thermal excitation; ion-neutralmomentum coupling; and the tidal waves arising in the lower atmosphere which penetrate the thermosphere. In the TIEGCM, the development of the MTM is due to the upward propagating semidiurnal tides. The model simulations suggest that the observed seasonal variation of the MTM, in which the MTM occurs earlier and more strongly in the local summer hemisphere, may be due to the interaction of the 2,2 and 2,3 modes: in summer, the two modes reinforce each other, and in winter they offset each other. This study further suggests that much of the variability observed in the MTM may be due to the variability in the upward propagating tides. The semidiurnal modal mix impinging on the lower thermosphere may vary on a day-to-day basis, depending on the background mean temperature and winds.


In the present budget environment, there is a strong need to drive down the cost of space missions. There is the perception that small satellites are inherently much lower cost than more traditional, larger satellites and can play a central role in reducing overall mission cost, but this effect has been difficult to quantify. Without quantifiable evidence of their value, we believe that small satellites are under-utilized as a method for reducing mission costs. The purpose of this study is to quantify the relationship between cost and performance for Earth observation systems. We conclude that for an Earth observation system, an increase in performance, reduction in cost, or both, is possible by using multiple SmallSats at lower altitudes when compared to traditional systems. This paper provides an estimate for the level of cost reduction. Specifically,