This paper presents the results of an experimental study on the effect of suction on compressibility and shear behaviour of unsaturated silty soil under various types of loading. A series of laboratory experiments were conducted in a double-walled triaxial cell on samples of a compacted silty soil. In the experiments the soil samples were subjected to isotropic consolidation followed by unloading and subsequent reloading under constant suction and prescribed overconsolidated ratio. The experimental results are presented in the context of an elasto-plastic model for unsaturated soil. The effects of suction on mechanical behaviour of unsaturated silty soil are presented and discussed. It is shown that increasing suction affects the shear behaviour of unsaturated soils, but there is a limit beyond which, further increase in suction will not result in any significant change in the behaviour.


Augmented reality (AR) aims to combine real and virtual worlds, offering real-time 3D interactions between users and virtual information. Existed AR systems detect specific markers in environments and augmented them with virtual contents such as 3D objects and videos. With the explosive growth of powerful, less expensive mobile devices, AR systems are extended to mobile devices. However, they fail to achieve the accurate and real-time integration of the real world and virtual contents because of the insufficient detection accuracy to objects in real world and computational resource shortage. In this paper, we propose a hybrid AR framework that integrates cloud computing, 5G communication and deep learning technology to achieve accurate tracking and ultra-low latency mobile AR applications. Our AR framework contains three blocks, an image capturing block, a deep learning based objects tracking block and a WebGL based rendering block. We use cloud computing technology to deploy them on mobile devices and a cloud server separately according to calculation amounts and use 5G to achieve communication between the cloud server and mobiles devices. The experiment results show that the accuracy and running speed of our framework can meet the requirements of most mobile AR applications.


There are three problems that are formulated in this study. The first question is used to describe the characteristics of the male and female characters in this play. The second question is used to give the evidence about the existence of binary opposition in the characteristics of the male and female characters. The third question is used to examine the binary opposition in the characteristics of male and female characters related to gender stereotype using the Deconstruction perspective.


We present an evaluation of the $\pi^\pm$ and $K^\pm$ box contributions to the hadronic light-by-light piece of the muon's anomalous magnetic moment, $a_\mu$. The calculation of the corresponding electromagnetic form factors (EFFs) is performed within a Dyson-Schwinger equations (DSE) approach to quantum chromodynamics. These form factors are calculated in the so-called rainbow-ladder (RL) truncation, following two different evaluation methods and, subsequently, in a further improved approximation scheme which incorporates meson cloud effects. The results are mutually consistent, indicating that in the domain of relevance for $a_\mu$ the obtained EFFs are practically equivalent. Our analysis yields the combined estimates of $a_\mu^{\pi^\pm-box}=-(15.6\pm 0.2)\times 10^{-11}$ and $a_\mu^{K^\pm-\text{box}}=-(0.48\pm 0.02)\times 10^{-11}$, in full agreement with results previously obtained within the DSE formalism and other contemporary estimates.


pathogens. Toxic shock syndrome was excluded because an exotoxin-producing staphylococcus was not isolated. Serial electrocardiographs showed changes consistent with hypocalcaemia on day I, and hyperkalaemia and day 3, otherwise they were normal. There was evidence of liver and pancreatic dysfunction, with raised levels of liver enzymes and amylase in the blood. Recovery was complicated by multiple rightsided focal fits of short duration, and his EEG showed generalized slow-wave activity, which was prominent and focal in the left temporal region. He gradually regained consciousness, and at the end of the second week there was a left hemiparesis. During the next four weeks he steadily improved; on discharge from hospital he could sit unsupported and feed himself, and his left hemiplegia had become less dense. The patient is now 3 years and 6 months of age; his residual disabilities are a mild paraplegia and slight speech delay, but otherwise his psychomotor development is normal.


Over the past century, global-scale climate warming has been accelerating, and climate change is drawing increasing attention from the media and the public. Surface air temperature (SAT) is the major subject of concern within the context of climate change. Starting in the second half of the last century (after 1950), the warming of the climate has been obvious at the global scale (Brohan et al. 2006; Hansen et al. 2010; Lawrimore et al. 2011; Jones et al. 2012; Morice et al. 2012; Vose et al. 2012; Hartmann et al. 2013). In the Intergovernmental Panel on Climate Change's (IPCC) Fifth Assessment Report (AR5) headline statements from the Summary for Policymakers, it was noted that many changes in the climate system since 1950 are unprecedented when compared to earlier decades. From 1880 to 2012, the global average sea and land surface temperature shows an increasing linear trend of 0.85°C. From 2003 to 2012, the average temperature increased by 0.78°C (0.72°–0.85°) compared with that from 1850 to 1900 (Hartmann et al. 2013). Further, IPCC AR5 notes that the warming rate has slowed down recently (1998–2012). This short 15-yr period has been discussed by a number of authors (Easterbrook 2008; Easterling and Wehner 2009; Kaufmann et al. 2011; Fyfe et al. 2013; Guemas et al. 2013; Met Office 2013a,b,c; Karl et al. 2015; Lewandowsky et al. 2016). Brohan et al. (2006) indicated that temperature series have three types of uncertainty: station errors, sampling errors, and bias errors. For China, the observational (station) errors in the SAT series are relatively small and well understood. Errors caused by the homogeneity adjustment of temperature series have been evaluated and discussed (Jones et al. 2008; Li et al. 2010a). Sampling errors in China are an issue when the number of observational sites is reduced


Increasingly, two key trends, value and cost conscious customers and globalization of markets and supply-sources, are shifting the competitive focus from the competitive advantage of firms to competitive advantages of entire supply chains. At the same time, the possibilities for flexibility and coordination inherent in modern information and communication technologies are making it possible to design and follow a much greater variety of organization and governance strategies for delivering customer value. The primary contribution of this paper is to develop general principles for ICT-enabled re-design of supply chains. Rather than examine the individual impact and design implications of each new ICT innovation, this paper proposes principles of abstraction that can be used to frame supply-chain re-design options and decisions. It goes on to show how these principles lead to flexibility in the design of various supply chain options thereby providing cost and value advantages for the supply chain. From Static Supply Chains to Dynamic Supply Webs: Principles for Radical Re-Design in the Age of Information


To the Editor.— As I was thinking about the patient smoking in the elevator under the "No Smoking" sign, the nurses smoking in the floor conference room under the "No Smoking" sign, the anesthesiologist smoking in the doctors' lounge under the "No Smoking" sign, my postgraduate year-5 surgery resident, my pediatrics preceptor, the chairman of the anatomy department, the president of the medical college, and many more, I began to wonder if I am truly in a health profession.


Abstract Owing to population growth and urbanization, there has been an increase in the number of auto mechanic workshops, vulcanizer's shops and engine oil retail shops along the roads within Nsukka with a direct increase in heavy metal concentration in dust. Emissions from these activities pose serious environmental concern along the major roads. This study is centered on the assessment of heavy metal pollution in dust and top soil along major roads within Nsukka metropolis. Soil and dust samples were collected along major roads at maximum distance of five meters from the roads edge, with control samples collected 400 m away from the nearest road. Heavy metals (Cadmium, Zinc, Iron, Lead, Chromium, Arsenic, Copper, Nickel, and Manganese) concentrations in the dust and soil were analyzed using Atomic Absorption Spectrophotometry method. The result of the analyzed heavy metal concentration showed no significant variation from the background concentration. The concentrations of Pb and Cr showed little variation, whereas As showed the greatest variation from the background value. The results of heavy metals contamination factor in soil and dust ranged from low contamination to very high contamination (CF < 1; to CF ≥ 6). High and very high contamination values were obtained for As, Cr, and Mn in both dust and soil samples. The enrichment factor of heavy metals ranged from EF ≤ 1 (background rank) to EF> 40 (extremely high enrichment). Among the analyzed heavy metals, Zn, Pb, As, and Cr showed the highest enrichments in both soil and dust samples respectively. The result of Igeo ranged from Igeo ≤ 0 (uncontaminated) to 2 < Igeo < 3 (moderately to heavily contaminated). In the dust and soil samples, Igeo for Zn, Pb, Cd, Ni, and Cu show no contamination; Igeo for As and Cr showed moderate contaminations in some locations whereas that of Mn showed moderate to heavy contamination. Results of PLI ranged from PLI < 1 (no pollution) to 3


Annotation. It is discussed in the article that some tools for drawing plant-based pattern elements related to woodworking and the additional equipments used in the teaching of drawing process.


ABSTRACT Ring-opening reactions of oxetanes yield important functionalized products depending upon the nature of nucleophiles as well as substitution pattern on the oxetane ring. Ring opening of oxetanes can be carried out under a variety of reaction conditions. In this review article, an up-to-date overview of major synthetic methodologies involved in the ring opening of oxetanes as well as their synthetic applications has been presented. GRAPHICAL ABSTRACT


Objective To investigate the expression of Beclin1 and PTEN protein in the epithelial ovarian carcinoma and their relationship with clinic characteristic.Methods The expression of Beclin1 and PTEN protein in 25 cases of normal ovary,25 cases of benign ovarian tumor,19 cases of borderline ovarian tumor and 69 cases of epithelial ovarian cancer tissue were detected by immuohistochemical method.Results(1)The high expression of Beclin1 and PTEN was found in normal and benign ovarian tumor tissues.The expression decreased in the borderline ovarian tissues,and was the lowest in the ovarian cancer(P0.05).(2)The expression of Beclin1 and PTEN in stage Ⅰ-Ⅱ,high and middle grade and negative lymph node metastasis epithelial ovarian cancer were higher than that in stage Ⅲ-Ⅳ,low grade,positive lymph node metastasis ovarian cancer(P0.05).Conclusion The expression of Beclin1 and PTEN is down-regulated in the epithelial ovarian cancer.This may play an important role in the initiation and development of ovarian cancer.


Raw NaHCO3 from prodn. of soda was used for desulfurization and redn, of N oxides of flue gases from a pilot fluidized-bed boiler (0.1 MW) at Na/S mass ratio 0.4-3.0. The processes were carried out at 300 degrees C both in the flue gas channel and at filtration stage. The efficiencies of the desulfurization and redn. of N oxides were 28-88% and 15-48%, resp., and increased with the increasing Na/S ratio.


Envisioned muon ionization cooling channel is based on vaccum and/or gas-filled RF cavities of frequencies of 325 and 650 MHz. In particular, to meet the luminosity requirement for a muon collider, the muon beam intensity should be on the order of 10 12 muons per bunch. In this high beam intensity, transient beam loading can significantly reduce the accelerating gradients and deteriorate the beam quality. We estimate this beam loading effect using an equivalent circuit model. For gas-filled cavity case, the beam loading is compared with plasma loading. We also investigate the excitation of higher-order modes and their effects on the performance of the cavity.


David Cesarani died in October 2015. With his passing, we lost a friend, a scholar and one of Britain's most prominent public intellectuals. David did more than anyone else to develop what has come to be known as 'Holocaust consciousness' in the United Kingdom. As director of the Wiener Library, as consultant to the All-Party Parliamentary War Crimes Group, as advisor to the Holocaust Memorial Day Trust and to the Imperial War Museum (IWM) in preparing its Holocaust Galleries, as regular commentator in the press and, not least, as editor of Patterns of Prejudice, David's energy and conscientiousness ensured that he was an outstanding figure. Today, if Holocaust consciousness seems deeply embedded in British society—in education (for all its shortcomings), in museums and memorials, in commemorative practices around Holocaust Memorial Day, in research institutions and in the more nebulous 'collective memory'—this is largely thanks to David's tireless campaigning. David did not begin his career as a Holocaust historian. Rather, he was interested as a graduate student at Cambridge in the history of British Jews and their relationship with Zionism. Together with a small group of like-minded scholars, including Tony Kushner, David Feldman and Bryan Cheyette, he reshaped the history of British Jewry, establishing a critical historiographical approach as the norm, setting the bar high for serious analysis that moved away from hagiography and 'communal defence', and placing the history of the Jews firmly in the context of general British history, including imperial and global history. Thus David's earliest published articles dealt with anti-alienism in England after the First World War, the Jews in Britain during that war, and Zionism, anti-Zionism and antisemitism in Britain in the 1920s. The volume that he edited in 1990, The Making of


An investigation made for two years (2007-08 and 2008-09) at Agricultural farm of Shri Durga Ji Post Graduate, College of Chandeshwar, Azamgarh (UP), India to find out the effect of varieties (Malviya-2, Aparna, Sapana and Rachana) and phosphorus levels (0, 20, 40, 60 and 80 kg/ha) on growth and yield attributes and yield of pea (Pisum sativum L.) in saline- alkaline soil. All the treatments were tested in three replicated Randomized Block Design. The results indicated that the Sapana variety gave highest growth attributes viz. plant height, branches/plant, dry weight/plant and days to 50% flowering and maturity yield attributes viz., pods/plant, pods weight/plant, grains/pod and test weight and yields viz. grain yield, straw yield and harvest index, which was significantly inferior to all other varieties of pea during both the years. The application of phosphorus @80 kg/ha produced significantly higher all observed growth attributes, yield attributes and yield of pea which is at par with the application of phosphorus @ 60 kg/ha except growth attributes during both the years. Therefore, used Sapana variety along with 60 kg/ha P2O5 proved to be all yield attributes and yields of pea during both the years, respectively.


In 1936, Polya introduced the concept of a counting polynomial in chemistry.
However, the subject established little attention from chemists for some decades even though the spectra
of the characteristic polynomial of graphs were considered extensively by numerical means in order
to obtain the molecular orbitals of unsaturated hydrocarbons. Counting polynomial is a sequence representation
of a topological stuff so that the exponents precise the magnitude of its partitions while the coefficients
are correlated to the occurrence of these partitions. Counting polynomials play a vital role in
topological description of bipartite structures as well as counts of equidistant and non-equidistant edges
in graphs. Omega, Sadhana, PI polynomials are wide examples of counting polynomials.

 Mathematical chemistry is a division of abstract chemistry in which we debate and forecast
the chemical structure by using mathematical models. Chemical graph theory is a subdivision of mathematical
chemistry in which the structure of a chemical compound can be embodied by a labelled graph
whose vertices are atoms and edges are covalent bonds between the atoms. We use graph theoretic
technique in finding the counting polynomials of TiO2 nanotubes.

Let ! be the molecular graph of TiO2. Then (!, !) = !!10!!+8!−2!−2 + (2! +1) !10!!+8!−2! + 2(! +
1)10!!+8!−2

In this paper, the omega, Sadhana and PI counting polynomials are studied. These polynomials
are useful in determining the omega, Sadhana and PI topological indices which play an important role in
studies of Quantitative structure-activity relationship (QSAR) and Quantitative structure-property relationship
(QSPR) which are used to predict the biological activities and properties of chemical compounds.

These counting polynomials play an important role in topological description of bipartite
structures as well as counts equidistance and non-equidistance edges in graphs. Computing distancecounting
polynomial is under investigation.


This paper tries to explain the sense in which the representation of deliberation in the Popol Vuh. In addition, situations where this is shown to guide the direction of the search for the interaction between men and analyzed gods. Is postulated to the performances are as subtext an appeal to reason as imperative for the existence and for the advent of the human. Similarly, it is argued that the advent of humanity is a result of the requirement and exercise of deliberation practicing the gods, and that demand should also have your creation. KeywoRds: Deliberation, reason, creation, destruction, communicative


Two Cu-Al single crystals with 7 and 14 at. % Al respectively have been studied using isothermal mechanical spectroscopy (IMS) technique. After a 1% cold work by torsion, the samples have been progressively heated to 1140 K and then cooled until room temperature. IMS experiments allow to compare the isothermal internal friction spectra obtained during the heating (in this case, the annealing temperature is equal to the temperature of measurement) with the measurements performed at various temperature during the cooling after the annealing at 1140 K. Three relaxation peaks were observed. The first one at about 0.4 TM (TM: melting point) is a Zener relaxation peak (PZ) due to the reorientation under constraint of pairs of aluminium atoms. The high temperature annealing does not influence PZ. At about 0.6 TM, a peak (P1) related to a dislocation mechanism is evidenced. The relaxation strength of P1 peak decreases with the temperature and a new relaxation peak (P2) is progressively developed. The IMS spectra obtained during the cooling evidenced only P2. The relaxation parameters obtained by the Arrhenius plots and the evolution with the annealing temperature allow to assign P1 and P2 to an interaction between the dislocations and the solute atoms according to the Darinskiy model. © 2009 Elsevier B.V. PACS: Type pacs here, separated by semicolons ;


This research was conducted to evaluate influence of cassava subtitution with calocasia to· quality and self life chicken meat bowl. The experiment design was arranged by campletely randamized block design with 5 treathment and 4 replication. CasstWa and calocasia subtitution level were used as a treatmen. i.e. A(lOO% : 0%),B(75% : 25%), C(50% : 50%), D(25% : 75%), E(O% : 100%). The parameters were evaluated as water value, pH, Total colony count and selflife. The result showed subtitution of cassava with calocasia powder could increase selflife ofchicken meat bowl. The best cambination casstWa and calocasia (0%:100%) was recamanded to produce good quality gelatin ofchicken meat bowl.


We compute the renormalized stress–energy tensor (RSET) of a massless minimally coupled scalar field in the regularized Polyakov approximation, as well as its backreaction, on the classical Reissner–Nordström spacetime. The complete set of solutions of the semiclassical self-consistent equations is obtained and compared with their classical counterparts. The semiclassical Reissner–Nordström family involves three kinds of geometries that arise depending on the charge-to-mass ratio of the spacetime. In the under-charged regime, the geometry has its external horizon replaced by a wormhole neck that leads to a singular asymptotic region at finite proper distance. The over-charged regime reveals a naked singularity surrounded by a cloud of (infinite) mass coming from the quantized field. Between both behaviours there is a separatrix solution reminiscent of the extremal black hole classical geometry. As the RSET over an extremal horizon is finite, the semiclassical backreaction does not get rid of the horizon. Nonetheless, we show that the resulting horizon is singular.


Thank you for downloading obsessive compulsive disorders. Maybe you have knowledge that, people have look hundreds times for their favorite novels like this obsessive compulsive disorders, but end up in malicious downloads. Rather than reading a good book with a cup of tea in the afternoon, instead they juggled with some harmful virus inside their desktop computer. obsessive compulsive disorders is available in our digital library an online access to it is set as public so you can get it instantly. Our books collection hosts in multiple countries, allowing you to get the most less latency time to download any of our books like this one. Kindly say, the obsessive compulsive disorders is universally compatible with any devices to read.


This study investigated the critical response of the curved ramp bridge deck pavement under coupled thermo-mechanical loads through a three-dimensional (3D) tyre-bridge interaction numerical model. The temperature fields of bridge deck pavement in different seasons were simulated using measured air temperature and solar radiation data. The influence of seasonal temperature changes on the viscoelastic behaviour and stress accumulation of the deck pavement layer were assessed according to the changes of dissipated energy under different cyclic thermal loads. The results indicated that varying load modes could result in different damage patterns and adverse load locations. The deck pavements above the diaphragm and longitudinal clapboard have better thermal fatigue resistance when subjected to the cyclic thermal loading; while the ones near the flange cantilever panel have stronger resistance to coupled thermo-mechanical load. Compared with the tyre load, the coupled thermo-mechanical load can yield larger critical response and more potential damage initiations.


This chapter determines what data people need to generate better health. People are simply not in contact with the health care system very often. Thus, insofar as health is shaped by where and how people live, it is a product of where people are between visits to doctors and hospitals. It must be something, then, about all the time people spend away from medical care that determines their health. As such, the apps and systems that collect data should be used to gather information on home life, time spent at work, and time spent in schools and in places of worship—the time that truly shapes people's health. Innovation in this area of data collection could break new ground, paying dividends for those who pioneer it and for those who reap the health benefits of these emerging tools.


A copolymer, having an overall composition of 1 unit of vinylpyridine to 26 units of vinylpyrrolidone, was synthesized. Several alkyl copolymers were made by quaternizing the nitrogen of vinylpyridine units of the copolymer with normal alkyl bromides, ethyl through hexyl. Using an equilibrium dialysis procedure, the interaction of p-toluene sulfonic acid sodium with each alkyl copolymer was studied over a temperature range of 15-45°, and the binding constants and thermodynamic parameters were determined. The quaternized vinylpyridine units of the alkyl copolymers constituted the binding sites for the p-toluene sulfonate ions. The stability of the complex formed in the reaction increased with an increase in temperature from 15-37° but decreased at 45°. The binding process was found endothermic and associated with positive entropy effects, indicating that the polymeric model system described here demonstrated properties expected for hydrophobic bonding. The effect of urea on the binding of sulfonate ion by one of the alkyl copolymers was studied and found to be in keeping with the claim that urea breaks hydrophobic bond.


An automatic wiring device guided by a guide rod and used in electrical equipment with a two-phase circuit is used to connect a two-phase circuit connection wire (2) to the electrical equipment. The electrical equipment comprises a wiring port frame (9), a positioning motor (7) which is fixed in a lower substrate (98) of the wiring port frame (9), and two circuit wiring execution assemblies (100, 200) which are arranged symmetrically about the axis of rotation of the positioning motor (7) and are respectively used to execute wiring operation of one phase of the two-phase circuit. The structure of the wiring port frame (9) is also arranged symmetrically about the axis of rotation of the positioning motor (7).


Detecting new and unknown malware is a major challenge in today's software. Security profession. A lot of approaches for the detection of malware using data mining techniques have already been proposed. Majority of the works used static features of malware. However, static detection methods fall short of detecting present day complex malware. Although some researchers proposed dynamic detection methods, the methods did not use all the malware features. In this work, an approach for the detection of new and unknown malware was proposed and implemented. Each sample was reverse engineered for analyzing its effect on the operating environment and to extract the static and behavioral features.


T H A T Gravcs's disease (exophthalmic goitre) owns heredity must be i ,; now regarded as fully established. The disorder must take its place in , "• the rank of neurotic complaints, since its nervous affinities are as well ; * marked as those of any other well-defined " nervous disease." } • ' • ' '" Trousseau noted the connection. Pepper saw it in mother and son; and Renoud also. Mackenzie saw it in two sisters. Cheadle recorded its occurrence in an aunt and three nieces. Silva found that in one case I the sister was epileptic ; in a second case the father died of apoplexy, *',;,• and the mother was neurasthenic ; in a third case the daughter had -'r\ chorea, and in a fourth case a sister had (iraves's disease. ;.,: Edward Bull noted that in one case the mother was hysterical, and 'f: the sister of the mother had Graves's disease. In a second case the "•"•[•, grandmother had had a thick skin, the mother was hysterical and ,;,! anaemic, suffered from struma, with rapid pulse ; a sister of the mother f had heart disease, two sisters of the patient had goitre and exophthalmos, > and were ana?mic. Another case was highly instructive. The father of . < the patient died suddenly from heart disease ; a sister of the father died i • of phthisis. This sister had fourteen children, most of whom had !', ', asthma. One other sister died of "cholerine" ; one of her children died of phthisis, two others had chlorosis and palpitation,—one of these had ' six children, all of whom were very nervous and chlorotic. The six ' sisters of the patient had all rapid pulses and palpitation, one of whom , died of apoplexy and one other of cardiac disease. \ Osterreichernoted a case in a family with the following extraordinary ;, history :— ;'^ A hysterical mother had ten children, two of whom presented no


How to Implement Effective Management Measures for Extracurricular Sports Activities in Junior Middle Schools Hongbing Liu ZhuanQiao Middle School, Fairy Town, Jiangdu District, Yangzhou, Jiangsu, 225200, China Abstract An important goal of junior high school teaching is to lay a good foundation for students' psychological and physical qualities. Junior high school physical education plays a very important role in cultivating students' comprehensive quality, and physical extracurricular activities are an important part of the development of junior high school physical education and an important means of cultivating students' physical and mental development. The paper analyzes the significance of extracurricular sports activities in junior high schools and the current situation of sports activities, and proposes feasible strategies for the existing problems, hoping to promote the development of junior high school sports teaching.


Recurrent pregnancy loss (RPL) is a common disease characterized by immune dysfunction and vitamin D deficiency. This study aimed to investigate vitamin D metabolism and γδT cell phenotypes at the maternal–fetal interface in women with early normal pregnancy (NP) and RPL and to determine the effects of vitamin D on the functions of γδT cells and their crosstalk with trophoblasts.


Using Kariya's bond pricing (1993) model, whose empirical pricing capability for non-defaultable bonds has been shown for Japanese Government bonds (JGBs) in Kariya and Tsuda (1994) and Kariya, et.al (2012), this paper makes a comprehensive empirical analysis on US Government bond (USGB) prices for a period including the Financial Crisis in 2008 and makes some comparisons with the results of JGBs. The model is a cross-sectional model that simultaneously values individual fixed-coupon (non-defaultable) bonds of different coupon rates and maturities via a stochastic discount function approach. In this paper we first clarify the theoretical relation between our stochastic discount function approach and the spot rate or forward rate approach in mathematical finance. Then we make a comprehensive empirical study on its pricing capability for individual USGBs with different attributes and its capacity of describing the movements of term structures of interest rates that USGBs imply as yield curves. Based on various tests of validity in a GLS (Generalized Least Squares) framework we propose a specific formulation with a polynomial of order 6 for the mean discount function that depends on maturity and coupon as attributes and a specific covariance structure. It is shown that even in the middle of the Financial Crisis, the cross-sectional model we propose is shown to be very effective for simultaneously pricing all the existing USGBs and deriving and describing zero yields.


Purpose: This study was conducted as a descriptive study to determine the needs of intensive care nurses for consultation-liaison psychiatric nursing about psychosocial care of patients. Method: The study was completed with 80 nurses working in the adult intensive care units of a university hospital. Data were collected online with a data collection form consisting of two parts. Necessary permissions were obtained for the study.Frequency, percentage, mean and standard deviation were used in data analysis. Since the data collected in the study were not normally distributed in the groups, Mann-Whitney U test was used in paired group comparisons and Kruskal Wallis-H test was used in comparisons of three or more groups. In case of statistically significant difference as a result of Kruskal Wallis-H Test analysis, Bonferroni correction and Mann-Whitney U Test were used in pairwise comparisons. P<0.05 was accepted for statistical significance. Results: According to the research findings, the mean score of the psychosocial needs of the nurses was found to be 22.63±10.16 out of 30 points, higher than the response to the physiological needs and the need for consultation to CLPH. The mean general knowledge level of the nurses was found to be 59.50±20.74 out of 100 points. Conclusion and Suggestions: It is seen that intensive care nurses need to cooperate with consultation liaison psychiatric nursing about the psychosocial care of patients. It is recommended that consultation-liaison psychiatric nursing should be expanded in our country in order that this cooperation will benefit institutions, patients and nurses.


This study seeks to analyze the effect of logistics management carried out by warehouse operators, the facilities and access provided to support storage, and the competitiveness of storage costs on the use of warehouse financing by suppliers in Central Java, Indonesia. The sampling method was purposive random sampling. The numbers of respondents involved in this study were 120 suppliers and farmers producing first-rate agricultural products and who are users of warehouse receipts in the Central Java region. By using linear regression analysis with assistance, the study results found that the variables of logistic management, facilities and supply chain access as well as competitive storage costs have positive and significant effects on the use of warehousing financing by suppliers and farmers who use public warehousing. This result confirms that the more precisely warehousing is managed, the higher the level of trust of users involved in the logistics business and supply chain of agricultural products to use additional services in the form of warehouse receipts to support the sustainability of agricultural businesses.


Dear editor, Breast cancer was the most common cancer and had the highest mortality rate in women worldwide.1–4 Yuanhuacine (YHC), a daphnane-type diterpenoid as the main active ingredients, inhibited breast cancer cell growth, but the detailedmechanismhad not yet been described.5,6 This study aimed to investigate the target of YHC that induced breast cancer cells death and explored the underlying mechanisms. Our previous studies showed that YHC exhibited significant inhibitory activity against various human tumour cell lines, especially breast cancer cells.5 Thus, we tested the cytotoxicity of YHC against MCF-7, MDA-MB-361 and BT549 breast cancer cells in vitro by MTT assay with Tamoxifen (Tam) and Doxorubicin (Dox) as the positive controls (Table S1). The results showed a concentrationdependent decrease in the viability of breast cancer cells after treatment with YHC (Figure S1A–C). Moreover, YHC was less toxic than positive controls (Dox and Tam) on human normal breast epithelial cells MCF-10A cells (Figure S2). Xenograft models were established for evaluating the anti-tumour effect of YHC (Figure 1A). YHC significantly inhibited the growth of xenograft tumours (Figures 1B–D). Themice's bodyweight was not affected by YHC treatment (Figure 1E), indicating that the dosage of the treatmentwas not overtly toxic. Additionally, each organ was not notably different among the YHC-treated groups and the control groups (Figures 1F–K,Table S2). Furthermore, tumour tissues from the YHC group revealed a lower level of Ki-67 expression by immunohistochemistry (Figure 1L). Compared with the control group, YHC-treated cells exhibited nuclear condensation and fragmentation, which were hallmarks of apoptotic cells (Figure S3A). Next, apoptosis in breast cancer cells was observed after YHC was stained with Annexin V-FITC/PI and Western blot (Figures S3B–E). DARTS/MS method had a powerful advantage identifying targets of natural products.7,8 YHC treatment-enriched


I gently touch the water. A swift current caresses my hand, and a sudden cold seeps into my body. The water is very clear. At this angle, I can see the river bed – sand, stones, and moss fluttering in the current. Upstream, the light is intense – sharp reflections on the rapids seem almost brighter than the low afternoon sun. Downstream, the light is gentle – shifting blues and greens reflect the sky and the surrounding foliage. I sit on a large stone by the river's edge. Willows and a few aspens line the river bank. My mind gently floats to a memory of nearly twenty-five years ago. In a yoga class in Pune, India, B.K.S. Iyengar states, 'Some people say that you must go out into nature in order to grow spiritually – but there are many ways'. I agree with him – infinite ways. But touching water is an old way – not quite timeless, but ancient, ancient.


Purpose: Lacrimal gland ptosis has a prevalence of 10% to 15% in Caucasian patients, reaching up to 60% in older age. Its involuntary resection during blepharoplasty carries the potential risk of compromising corneal lubrication. The purpose of this systematic review is to check whether there is a consensus in the literature regarding the surgical procedure of choice and which outcomes and complications have been observed. Methods: A systematic review was carried out following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A search was carried out in the Medline, Scopus, and Cochrane databases in March 2022. Results: A total of 16 studies involving 483 patients with lacrimal gland ptosis have been included. In 90.06% of patients, resuspension or direct refixation of the gland to the lacrimal fossa with suture to the orbital periosteum was performed. Follow up has been inconsistent, with an average of 18 months. Regarding complications, 5 recurrences and only 2 patients with persistent dry eye were observed. Conclusions: In general, the evidence is sparse. Nevertheless, repair of lacrimal gland ptosis is a relatively simple, reproducible, and safe surgical technique, with a low likelihood of recurrence, severe, or persistent complications. A classification is proposed for both the grading of ptosis and its treatment. The involuntary resection of the lacrimal gland due to its ptosis during blepharoplasty carries the potential risk of compromising corneal lubrication. The purpose of this review was to determine whether there is a consensus in the literature regarding the surgical procedure of choice for lacrimal gland ptosis and which outcomes and complications have been observed.


Background: Cancer is one of the most life threatening diseases which is in need of newer drug development. The use of plant products with potent antioxidant and cytotoxic activity is upcoming Studies reveal that herbal product have increased efficacy as well as decreased side effects, with this in mind the present study was undertaken to assess the antitumor activity of extracts of Glycyrrhiza glabra (GG) against ehrlich ascites carcinoma in swiss albino mice.
Methods: The extracts of roots of GG was collected and acute toxicity study was done following which the antitumor effect of extracts of GG was assessed by change in the body weight, mean survival time (MST), and percentage increased life span (% ILS). MST of each group containing six mice was monitored by recording the mortality daily for 6 weeks and % ILS was calculated. The hematological parameters and biochemical assays were also measured.
Results: Extracts of GG showed a significant reduction in % increase in tumor induced body weight of the mice. The % increase in life span was also significant in the higher dose of GG (500 mg/kg). The combination of GG with standard drug cisplatin had better efficacy in terms of % ILS, hematological and biochemical parameters. The results obtained were statistically significant.
Conclusions: The antitumor activity studies measuring the viability of cancer cells when exposed to the ethanolic extract of Glycyrrhiza glabra showed a potent cell-killing effect, indicating the presence of anti-cancer principles in the preparation.


Abstract: The demonetization has resulted the consumers to use the digital payment which was motivated by digital India campaign by the government of India .The Digi locker is a place where you can store your documents .The massive outbreak of the covid-19 has resulted the consumers to use the different digital payment methods available in the market. The purpose of this research is to know the spending pattern of the consumer in terms of digital payments. The research works was carried out with 172 respondents and the convenience sampling technique was adopted to collect the data. The structured questionnaire was used to collect the data. Based on the findings the suitable recommendations were made by the researchers.


The 1.06 μm breakdown thresholds of crystalline and amorphous SiO 2 were compared. These materials showed dependences of the breakdown threshold on the focal volume which are consistent with a multiphoton-assisted electron avalanche damage mechanism.


Objective:To evaluate the safety and effects of applying alteplase on treatement for acute pulmonary thromboembolism (PTE).Method: 20 cases of patients with moderate to severe acute pulmonary thromboembolism were selected from the hospital from July 2010 to June 2012 and were randomly divided into two groups.In 10 cases of catheter directed thrombolytic therapy group,a catheter was indwelt where the pulmonary arterial thrombosis occurred and 50 mg of alteplase was pumped through the catheter continuously for two hours.In peripheral venous thrombolytic therapy group,15 mg of alteplase was intravenous injected and the remaining 35 mg was intravenous infused for two hours.Changes in the results of blood gas analysis,echocardiogram,and CT angiography of pulmonary artery of the patients before and after the treatment were analyzed.Result:After one day and five days of treatment,the dyspnea symptoms were relieved for 20 patients in both groups,but the difference between some of the comparing indexes had statistical significance.Conclusion:When the same dose of alteplase was used for the same duration in treating acute pulmonary thromboembolism,catheter directed thrombolytic therapy was superior to peripheral venous thrombolytic therapy in short-term clinical outcomes.Therefore,we believe that it is safe to apply catheter directed thrombolytic therapy with alteplase in treating acute pulmonary thromboembolism,and the effect of which is better than the traditional peripheral venous thrombolytic therapy.


The purpose of the research was to establish the effect of the two programmes of physical activities with girls at pre-school age on their basic motor skills and morphological characteristics. The total number of 120 girls enrolled in nursery schools, at the age of 6±0,5 was divided to sub-samples, depending on the programme they participated in. The experimental group consisted of 73 girls, and the control group consisted of 47 girls. Both groups had regular physical activities in duration of six months, where the experimental group had organized classes of physical exercises five times a week and the control group only twice. Nine motor skills tests were used for monitoring the motor skills and three variables for morphological characteristics. ANOVA was used for determining the differences in motor skills and morphological characteristics in the initial and the final measuring.


Thesis (M.A.)--American University of Beirut, Center for Arab and Middle Eastern Studies, 2008.;"Advisor: Dr. Samir Khalaf, Professor, Social and Behavioral Sciences--Member of Committee: Dr. Samir Seikaly, Professor, History and Archaeology--Member of Co


Escherichia coli O157:H7 and Salmonella typhimurium are two of the most important foodborne pathogens causing gastroenteritis all around the world . Two samples were taken from chicken burger and meat sausage samples ,which prepared in a manner similar to commercial one . Then, samples inoculated with approximately 10 6 -10 7 cfu/g of E. coli O157:H7 and10 7 -10 8 cfu/g of S. typhimurium then, cooked by microwaving , grilling , frying and boiling . Following exposures to heat treatments, viable counts and temperature measurements were immediately performed. Elimination of E. coliO157:H7 inoculated onto chicken burger was observed after microwaving, grilling, frying and boiling exposure for 40 sec., 7 min., 2.5 min. and 1.5min. , respectively and after 35 sec., 8 min., 2 min., and 2 min., for meat sausage samples, respectively. S. typhimurium inoculated onto chicken burger was undetectable after microwaving, grilling, frying and boiling for 35 sec., 7 min., 1.5 min. and 1.2 min., respectively, and after 30 sec., 6 min., 1.5 min., and 1min., for meat sausage samples, respectively . This study showed that the lowest temperature degree at which elimination of E. coli O157:H7 was realized by microwave heating at 74°C for 40sec. and 66.6°C for 35sec. for both chicken burger and meat sausage. As for S. typhimurium, it was 65°C for 35 and 30 sec. for both chicken burger and meat sausage samples, respectively. This study also showed that E. coliO157:H7 was more heat resistant than S. typhimurium under the same conditions.


The purpose of the article is to provide a critical assessment of the institutional structure and capacity of the domestic audit system, to form a theoretical basis for strengthening its institutional effectiveness in the national interests and in the context of European integration and globalization of Ukraine's economy. Research methods. In the course of the research, the following methods were used: dialectical (in the knowledge of the substantive features of the institution of audit); monographic (analysis of the evolution of the institutional development of the audit institution); analysis (to clarify the compliance of the audit with the parameters of a socio-economic institution); synthesis and evaluation (for the study of Strategies and Concepts of the Audit Chamber of Ukraine); empirical (based on a comprehensive assessment of the current state of auditing in Ukraine); comparative analysis (the directions of integration of program documents for the development of the audit institute with the European Union and the International Federation of Accountants are determined), statistical (in the study of the state of audit activity in Ukraine); modeling and classification (to determine the internal structure of the audit institution, classification and hierarchy of its components); comparison (to prove the absence of heredity in the program documents of the Audit Chamber of Ukraine); abstrac1t-logical (theoretical generalizations of the directions of development of the audit institution in Ukraine and the formulation of conclusions). Research results. They consist in identifying the problems of heredity of program documents of the domestic audit system, their value guidelines and the formation of proposals for building an effective structure and hierarchy of components of the audit institution. Scientific novelty. They are associated with the use of an institutional approach to the periodization of the development of the audit system in Ukraine, ensuring its effectiveness through adherence to the hierarchy of components so characteristic of socio-economic institutions. Practical significance. The results obtained indicate the problems of the development of the domestic audit institution and the ways to overcome them using knowledge and approaches on the institutional theory of audit. Tabl.: 3. Figs.: 1. Refs.: 22.


Background:  The number of patients requiring carotid endarterectomy in our hospitals had been noted to be declining. Hence, our aim was to look at the numbers of carotid interventions in our State to see whether this trend was more pervasive and to look at trends in statin prescriptions over the same time‐course.


One of the things that makes Smalltalk development so much fun is that you can easily modify the development environment. If you don't like something, change it. This chapter contains examples of such changes. They are preferences of mine but not necessarily those of everyone (if they were so good, they'd be part of the standard image). To make the changes part of your standard environment, you can either save the image with your changes, or file the changes in every time you start up the image. For more information on filing in changes, see Chapter 33, Managing Source Code.


A general scheme of parameterized families of equations is considered, and abstract results on the expansion of the solutions and on the acceleration of their convergence in terms of the parameter are presented. These results are applied to fractional step approximations for linear parabolic PDEs, systems of linear PDEs, and for nonlinear ordinary differential equations. Applications to accelerating the convergence of finite difference schemes for these equations will be presented in a subsequent paper.


We report the first measurements of delayed ionization of the metallofullerene La@C82. When highly excited in laser desorption, La@C82 was found to ionize over several microseconds. The rate of delayed ionization of La@C82 was compared to C60 under the same extraction conditions, and found to be significantly different. A theoretical model was used for the fitting of the ion signal of the two fullerenes. The metallofullerene results can be fitted well over a time window <30 μs and are consistent with a low ionization potential (6.3 eV) and a high radiative cooling rate. The C60 data cannot be fitted over the same time window, indicative of an additional time-dependent competing decay channel.


[Objective] To test HBV DNA, HCV /HIV RNA by using PCR-Micoflluidic chips assay in blood donors, and to study the feasibility of PCR-Micoflluidic chips assay in blood donors. [Methods] To pool samples (5×200μL) negative for ELISA serological tests,and using a large-volume magnetic bead-fluid separation method to extract total nucleic acid, amplified by nest-PCR, and detected by micoflluidic chips system, and then we evaluated the sensitivity and efficacy by national controls. [Results] 3 of 342 donations were PCR for HBV DNA positive, and the DNA positive rate was 0.89%. The 95% limits of PCR-Micoflluidic chips assay were 11.5 IU/mL, 167.8 copy/mL and 57.9 IU/mL respectively. 2/3 donations were Anti-HBc and Anti-HBs positive. No positive HCV RNA and HIV RNA negative for antibody was detected. [Conclusions] PCR-Micoflluidic chips assay is convenient, time-saving, sensitive, specific and reproducible, and can be applied in the blood screening. It is necessary to implement HBV DNA screening in blood donors.


This scientific paper deals with management of all parties of maritime transport services with an emphasis on shipowner management for purposes of optimizing ship voyage costs by applying Virtual Arrival of the vessel to the port. Virtual Arrival is a process involving an agreement to reduce a vessel's speed during voyage due to berth occupancy at ship accommodation at the discharge port. The reduction in speed during voyage will result in reduced fuel consumption, which directly affects shipowner management, namely voyage costs. The proposed algorithm of Virtual Arrival defines interdependence of the parties of the maritime transport process as well as the actions undertaken in the following procedure of the arrival. The algorithm results show the possibility of creating a mutual financial benefit and display profitability of shipowner management and other parties of the Mutual Agreement. Furthermore, the paper analyzes Mutual Effects of the Virtual Arrival to all other represented parties of the maritime transport process. © Faculty of Maritime Studies Rijeka, 2015.


FIELD: oil and gas production. SUBSTANCE: device consists of drilling device on sea bottom pressure tight closed form environment. The device is filled with fluid and is equipped with the separator for separation of material from fluid. EFFECT: reduced pollution of environment. 6 cl, 2 dwg


Abstract Chronic inflammatory responses can inflict permanent damage to host tissues. Specialized pro‐resolving mediators downregulate inflammation but also can have other functions. The aim of this study was to examine whether oral epithelial cells express the receptors FPR2/ALX and DRV1/GPR32, which bind RvD1n‐3 DPA, a recently described pro‐resolving mediator derived from omega‐3 docosapentaenoic acid (DPA), and whether RvD1n‐3 DPA exposure induced significant responses in these cells. Gingival biopsies were stained using antibodies to FPR2/ALX and DRV1/GPR32. Expression of FPR2/ALX and DRV1/GPR32 was examined in primary oral epithelial cells by qRT‐PCR, flow cytometry, and immunofluorescence. The effect of RvD1n‐3 DPA on intracellular calcium mobilization and transcription of beta‐defensins 1 and 2, and cathelicidin was evaluated by qRT‐PCR. FPR2/ALX and DRV1/GPR32 were expressed by gingival keratinocytes in situ. In cultured oral epithelial cells, FPR2/ALX was detected on the cell surface, whereas FPR2/ALX and DRV1/GPR32 were detected intracellularly. Exposure to RvD1n‐3 DPA induced intracellular calcium mobilization, FPR2/ALX internalization, DRV1/GPR32 translocation to the nucleus, and significantly increased expression of genes coding for beta‐defensin 1, beta‐defensin 2, and cathelicidin. This shows that the signal constituted by RvD1n‐3 DPA is recognized by oral keratinocytes and that this can strengthen the antimicrobial and regulatory potential of the oral epithelium.


Coffee seedling growth depends on soil phosphorus (P) availability and may be influenced by from pre-cultivation with legumes. Efficient and sustainable ways to increase the bioavailability of P through the recovery of P adsorbed by the soil matrix should be sought. This study proposed to evaluate the growth and P-use efficiency of coffee seedlings cultivated in soils with different P availability after cultivation with legumes. The experiment was carried out in a fully randomized design. Treatments were arranged in a factorial scheme [(2 x 4) + 1]: two soil types, pre-cultivation with four legume species, and one control (withoutpre-cultivation). The studied soils comprised a Typical Acriferic Red Oxisol (LVwf) with low-P availability and a Typical Chernossolic Litholytic Entisol (RLm) with high-P availability. The legume species Crotalaria juncea, Cajanus cajan, Canavalia ensiformis, and Mucuna aterrima were previously cultivated for 45 days. Afterwards, coffee seedlings were transplanted to the pots, which were then grown for 120 days until evaluations. We assessed the following parameters: plant height (H), stem diameter (SD), shoot dry matter (SDM), root dry matter (RDM), total dry matter (TDM), and shoot contents of macronutrients. Our results showed that coffee seedlings grew more when cultivated in the high-P availability soil, with increments of 13.05% in H, 4.86% in SD, 46.98% in SDM, 17.61% in RDM, and 41.80% in TDM.We also observed an increase of 28.09% in shoot P contents for coffee seedlings grown in RLm. Moreover, pre-cultivationwith C. juncea provided the largest increases in coffee seedling growth compared to the control. When grown after C. ensiformis cultivation, coffee seedlings had the highest shoot contents of P, Ca, Mg, and S, which, compared to control, increased by 45%, 39%, 18%, and 17%, respectively.
Keywords: Canavalia ensiformis; Crotalaria juncea; Coffea arabica; phosphate fertilization; nutritional efficiency.


In a device for limiting the response region of an operating device radio-controlled by a remote control transmitter, there are at least two receiving aerials on the remote-controlled operating device arranged in different positions in relation to the transmitter, from the phase-shifted reception signals of which is obtained a control signal permitting switching processes in the operating device which ensure that, when a remote-controlled device reaches a maximum distance from the remote control transmitter, a definable switching process is triggered, e.g. the stopping of the drive or the issue of an acoustic or optical warning signal. Where a plurality of remote-controlled devices are used, such a measure is increasingly required because, for example, of work safety; here, the invention provides a simple technical conversion.


This paper summarized some relevant problems of the traditional Chinese medicine,amine neurotransmitter and sports central fatigue from the following three aspects."Central fatigue" hypothesis,amine neurotransmitter and its metabolism changes in sports;impacts of the Chinese medicine's on amine neurotransmitter;prospects of the traditional Chinese medicine in postponing and dispelling sports central fatigue.


Holographic soft-wall model is successful in the phenomenology of hadrons. Here with the use of generalized parton distributions (GPDs) obtained from AdS/QCD, perturbative effects are entered into the formalism. Perturbations are incorporated in the formalism through the evolution of GPDs according to the DGLAP like equations. Evolved proton GPDs are compared with a phenomenological model to show that we can get some improvements.


The organic chemical reaction is a process of covalent bond breaking and forming. A number of discussions and research during organic chemistry teaching have been given to the properties and applications of various organic compounds' covalent bonds. Compared with covalent bond interaction, noncovalent interaction bond is weaker. Nevertheless, noncovalent interactions widely exist in the individual compounds and among the compounds, and are extensively applied in the organic functional materials. This paper has investigated noncovalent interaction's effect on physical properties of organic compound, organic compounds' and their intermediates' stability, reaction activity, acidity and reaction direction of organic compounds and applications of organic compound properties from a unique respective. It is our expectation that effect of noncovalent interaction will be given more considerations in the organic chemistry teaching and learning, and our practices provide a new respective to the organic chemistry innovative ideas. Keywords—Noncovalent interaction; Organic chemical teaching; Application; Investigation


Clinical experiences with Dana Super IUDs for contraception in 120 women aged 20-42 years are reported. Temporary muscle spasm or bleeding irregularity was noted in about 20% of patients. Spontaneous expuslion of the device occurred in 5 patients while 3 were removed because of endometritis (2) and tubal pregnancy (1). In 1 case of partial expulsion pregnancy was diagnosed. Histological studies showed that the uterus tended to mold itself to the shape of the device; endometrial pressure atrophy mucosa hyperemia and necrosis were also evident. The authors discuss the advantages and disadvantages of the IUD and its mechanism of action.


To investigate the affect of Gastrodin on human gastric cancer cells (SGC7901) and its relationship with precursor brain‐derived neurotrophic factor proBDNF signal pathway.


This paper analyses the causes for lining brickwork damaged of equipment in Imperial Smelting Furnace of Shaoguan Smelter,describes the modification practice of lining brick.


Research and design a hydraulic speed regulating braking system for downward belt conveyor with using electro-hydraulic proportional valve,analyze the principle of the braking system and the braking process.According to actual conditions,design a fuzzy adaptive PID controller to control the openings of the electro-hydraulic proportional valve port,implementing a safe and smooth braking.


We review recent theoretical developments in understanding the intermittency phenomenon observed in high‐energy leptonic, hadronic, and nuclear collisions. In particular, we discuss self‐similar cascading and QCD parton showers, models with phase transitions, and the three‐dimensional statistical field theory of multiparticle density fluctuations.


Using molecular-dynamics simulation, we study the phase transformations in Fe thin films induced by uni- and biaxial strain. Both the austenitic transformation of a body-centered cubic (bcc) film at the equilibrium temperature of the face-centered cubic (fcc)–bcc transformation and the martensitic transformation of an undercooled fcc film are studied. We demonstrate that different strain states (uni- or biaxial) induce different nucleation kinetics of the new phase and hence different microstructures evolve. For the case of the austenitic transformation, the direction of the applied strain selects the orientation of the nucleated grains of the new phase; the application of biaxial strain leads to a symmetric twinned structure. For the martensitic transformation, the influence of the strain state is even more pronounced, in that it can either inhibit the transformation, induce the homogeneous nucleation of a fine-dispersed array of the new phase resulting in a single-crystalline final state, or lead to the more conventional mechanism of heterogeneous nucleation of grains at the free surfaces, which grow and result in a poly-crystalline microstructure of the transformed material.


Recent developments in virtual 3D audio and synthetic aural environments have produced a complex acoustical room simulation. The acoustical simulation models a room with walls, ceiling, and floor of selected sound reflecting/absorbing characteristics and unlimited independent localizable sound sources. This non-visual acoustic simulation, implemented with 4 audio ConvolvotronsTM by Crystal River Engineering and coupled to the listener with a Poihemus IsotrakTM, tracking the listener's head position and orientation, and stereo headphones returning binaural sound, is quite compelling to most listeners with eyes closed. This immersive effect should be reinforced when properly integrated into a full, multi-sensory virtual environment presentation. This paper discusses the design of an interactive, visual virtual environment, complementing the acoustic model and specified to: 1) allow the listener to freely move about the space, a room of manipulable size, shape, and audio character, while interactively relocating the sound sources; 2) reinforce the listener's feeling of telepresence into the acoustical environment with visual and proprioceptive sensations; 3) enhance the audio with the graphic and interactive components, rather than overwhelm or reduce it; and 4) serve as a research testbed and technology transfer demonstration. The hardware/software design of two demonstration systems, one installed and one portable, are discussed through the development of four iterative configurations. The installed system implements a head-coupled, wide-angle, stereo-optic tracker/viewer and multi-computer simulation control. The portable demonstration system implements a head-mounted wide-angle, stereo-optic display, separate head and pointer electro-magnetic position trackers, a heterogeneous parallel graphics processing system, and object oriented C++ program code.


This paper focuses on visualizations of the "Waldheim Affair" of 1986 and 1987 in several Austrian media. Although Waldheim and his wartime biography have been at the heart of several seminal works on Austrian politics of memory, the visual history of this paradigmshift ing event has not yet been examined. This article therefore aims at analyzing important "key images" and their functions and uses within the context of the "Waldheim Affair" and the process of Austria's "coming to terms" with its past. However, Waldheim and the subsequent medial uproar have to be analyzed against the backdrop of previous "critical discourse moments" that have contributed to setting the course for a thorough reexamination of Austria's role in wwii. This paper also explores the Kreisky- Wiesenthal confl ict in 1975 and the Reder- Frischenschlager handshake of 1985.


This article introduces Gamma-triangles, which are closely related to and more fundamental than F-triangles and H-triangles that have been used in the combinatorics of cluster complexes. It is proved that Gamma-triangles can be expressed as sums of the local gamma-vectors introduced by Athanasiadis, which themselves refine the local h-vectors attached by Stanley to simplicial subdivisions. Gamma triangles of all cluster complexes are then explicitly computed.


ABSTRACT During the 1990s, some OECD countries succeeded in reducing their budget deficits. The average public debt ratio fell from more than 70 per cent of GDP in 1996 to about 63 per cent of GDP in 2001. Up to now, researchers have mainly focused on the economic effects of these consolidation efforts. This paper answers another question: How can balanced budgets be achieved? By means of a detailed review of nine budget consolidations, the study identifies different roads to successful fiscal adjustments, starting with a critical review of the definition of budget consolidation. We find a pattern on the expenditure side that follows different worlds of the welfare state. On the revenue side however, the tax structure seems to be more path-dependent and mainly driven by long-term developments. In the last section, we show that institutional reforms constitute very important components of budget consolidations.


A thesis submitted to the Directorate of Research and Graduate Training (DRGT), in partial fulfillment of the requirements for the award of the degree of Masters of Science Degree in Environment and Natural Resources of Makerere University


The electromagnetic form factors of the Delta baryon are evaluated within the framework of a covariant spectator quark model, where S and D-states are included in the $\Delta$ wave function. We predict all the four Delta multipole form factors: the electric charge GE0, the magnetic dipole GM1, the electric quadrupole GE2 and the magnetic octupole GM3. We compare our predictions with other theoretical calculations. Our results are compatible with the available experimental data and recent lattice QCD data.


Devices, methods, and techniques for control and regulation of the mechanical/physical functions involved in implementing the space program are discussed. Section one deals with automatic controls considered to be, essentially, start-stop operations or those holding the activity in a desired constraint. Devices that may be used to regulate activities within desired ranges or subject them to predetermined changes are dealt with in section two.


The characteristics of seismic ground motions in southern China are difficult to determine statistically due to a lack of strong ground motion data. In this study, a stochastic finite-fault ground motion model was adopted to simulate the seismic ground motions at bedrock for southern China, based on parameters derived from small and medium earthquakes that have occurred in the region. From these, the response spectra was estimated. A set of ground motion attenuation relationships was then developed based on simulated peak ground motions and response spectral parameters through regression, which would be applicable for use in engineering practice. Through comparisons, it was demonstrated that the proposed ground motion relationships are generally consistent with those obtained from other reported ground motion attenuation models for southern China.


The suitability of active brazing technology for joining TiC-strengthened alumina (ATC) to itself and to stainless steel is evaluated. The main emphasis is put on the investigation of the microstructural and mechanical properties of the active brazed joints. Furthermore, the electrical properties are investigated by determining the specific electrical resistance of active brazed Al{sub 2}O{sub 3}/TiC joints. For fabrication of the joints two process technologies are applied: vacuum furnace brazing and induction brazing under shielding gas. Four-point bend tests revealed that some of the vacuum-brazed ATC joints reach bending strengths comparable to those of bulk ATC. The induction brazing process is shown to be applicable when ATC has to be joined to metals, as in stainless steel for example. However, mechanically tough ATC-steel joints can only be fabricated when using very ductile filler metals, which are able to compensate thermally induced stresses by plastic deformation.


In this work, a new approach was tested to assess the cellular composition of tissues by time-resolved methods of fluorescence analysis of exogenous and endogenous fluorophores. First of all, the differences in fluorescence kinetics of endogenous fluorophores (coenzymes NADH and FAD) in tumour and immunocompetent cells were determined. After that, differences in fluorescence kinetics of photosensitizer 5 ALA-induced protoporphyrin IX were established due to its different metabolism in cells of different phenotypes. Kinetics of photoluminescence of NADH and FAD coenzymes as well as photosensitizer were studied by means of two different methods: time-resolved spectroscopy based on a streak-camera and fibre optic neuroscopy, which served to perform process monitoring and regular fluorescence diagnosis of the probed region. Time-resolved fluorescence microscopy (FLIM) was used as a control technique. Time-resolved spectroscopic fluorescence lifetime analysis was performed on sexually mature female rats induced with glioma C6 brain tumour under in vivo conditions; thus, under conditions where the immune system actively intervenes in the process of oncogenesis. In this regard, the aim of the study was to recognize the cellular composition of the brain tumour tissue, namely the ratio of cancer and immunocompetent cells and their mutual localization. Understanding the role of the immune system thus provides new ways and approaches for further diagnosis and therapy, making tumour-associated immune cells a prime target for modern therapies.


p-type gallium nitride (GaN) layers were regrown on etched surfaces on free-standing GaN substrates by metalorganic chemical vapor deposition with different growth rates by adjusting trimethylgallium flow rates. The roughness of the samples increases almost linearly with the growth rate, with an increase rate of 0.6 nm (μm h−1) −1. The screw dislocation density of the samples increases significantly when the growth rate is higher than 0.5 μm h − 1. When the magnesium (Mg) doping concentration is higher than 7.0 × 1019 cm−3, transmission electron microscopy images clearly show the regrowth interfaces, and Mg precipitate occur in high-doping p-GaN layers. Under the same bis(cyclopentadienyl)magnesium (Cp2Mg) flow rate, the Mg doping concentration decreases with the growth rate. The samples with different growth rates show different electroluminescence spectra. The emission peak at 2.8 eV is due to the transition from the deep donor level to the Mg acceptor level. And the intensity of this peak drops with increasing growth rate due to reduction of Mg acceptors. Transitions related to defect levels appears with increasing growth rate due to an increased screw dislocation density.


The paper presents a newly developed, innovative idea on a global scale system for indoor navigation INCREDISCOPE. The system is fully autonomic, and it is based on e-paper displays technology. The original positioning and navigation system for people inside buildings gives the possibility to intuitively and naturally lead a person to the desired destination. The paper consists of four parts. In the beginning, the short introduction and basic assumptions about indoor navigation and positioning are given. Then the core idea of the system and basic assumptions are introduced. In the third section, some technical information of prepared software is presented. Three different applications were prepared – intended for the system administrator; designated for e-paper displays and a mobile application for users who move inside buildings with their smartphones. The recognition of the users is based on Bluetooth technology. In the paper, two versions of the administrator interface were presented (Admin 1.0 and Admin 2.0). The operation logic of each version is completely different. The first one was too time-consuming during relations table creation. The second one is more intuitive. The last part of the article includes conclusions and prospects for further development of the system.


Outlines the Department's methods in complying with the legal obligations set by the Freedom of Information Act in terms of its obligations, the processing of applications, designated responsibilities and methods of reporting.


The invention relates to a packaging module with the packaging film (6) to be wrapped containers or groups of items (5) on a horizontal conveyor (10, 11) standing in the direction of a packaging station (2) transported in the transport direction (TR) by means of a film-wrapping device (1, 20) are covered with a foil section (6) of defined length. The foil wrapping device (1, 20) comprises at least one of the two longitudinal sides of the horizontal conveyor (10, 11) by means Endloszugmitteln (12) guided transversely to the transport direction (TR) extending wrapping rod (18) on which the film portion (6) during the wrapping - and the turning operation is held clamped and / or performed. The endless tensile means (12) have respective guide portions (24) which define the position and deflection of the endless traction means (12). The corresponding guide portions (24) of the two mutually parallel endless traction means (12) can in pairs in the same direction in its vertical and / or horizontal position and / or around a pivot point (D) are adjusted in their angular position and / or the length of the guide sections (24) can be set.


Focus on aging as a process vs. (old) age as a state of life. How do needs for supporting information and information tools change through the years of a person's adult life? Of special interest in the context of successful aging are innovations that are better for all adults but work even better for people as they age. To identify innovations that "age well", begin by routinely sampling across a spectrum of adult ages, both in studies of current tool use (e.g., observations, interviews, surveys) and design alternatives. As a further step, cross age with other factors. Less formal methods involving forms of group deliberation can also elucidate age-related changes in the landscape of information need. A focus on the process of aging (vs. "old age") is inclusive of people across the decades of their adult lives.


Radiotherapy plays an important role in cancer treatment; however, the incidence of radio-resistance remains become major challenges in cancer treatment. The presence of epithelial-mesenchymal transition (EMT) has become a clinical hallmark for cancer to relapse after radiation treatment. The aim of this study was to investigate the morphological changes and cell survival of EMT6 cell line post–gamma ray irradiation. The irradiation of EMT6 cells was conducted with two approaches, first, EMT6 cells were treated with single dose of gamma-ray ranging low to high dose of gamma-ray (0-16 Gy) and second, EMT6 cells were exposed to fractionated gamma-ray irradiation (2 Gy per cycle) where cells that survive the initial irradiation were further irradiated with 2 Gy dose. Results showed that there were morphological changes in treated cell compared to sham-control cells in both irradiation approaches which include loss of glandular pattern, vacuolated cell plasma, pleomorphic nuclei and enlarged size. For survival fraction, the survival fractions were reduced with increasing dose compared to the sham-control in single dose reaction while for the fractionated irradiation, survival fractions were reduced until 3rd cycles and increased in 4th cycles and maintained until 6 cycles which showed resistance of EMT6. In conclusion, radiation therapy causes cell morphological changes and fractionation of gamma-ray irradiation lead to resistance EMT6 after 4 cycles.


This article presents a conceptual framework that illustrates four distinct types of accountability environments facing public managers. The framework is used as a heuristic tool to examine the broad facts and contexts surrounding the bankruptcy of the Orange County, California investment pool. The framework also suggests management philosophies and strategies that are appropriate for each type of accountability environment.


THIS paper will describe, on a systems basis, a new multichannel teletype terminal which has been designed for the main-line intercontinental radio circuits of the Army Command and Administrative Network (ACAN). This network provides the backbone of the traffic-handling facilities between the United States and major overseas commands largely utilizing single-side-band transmission and reception. The continuity of communications required in this service makes reliability of paramount importance. Therefore, the equipment must be capable of operating effectively under adverse conditions of long-range radio propagation. The heavy traffic load necessary in maintaining the extensive overseas forces imposes the additional major requirement of maximum communication channels per radio circuit. To meet the varied requirements for teletypewriter, voice and facsimile channels, and the rigors of service in poorly controlled environments sometimes necessary in military operations, a basically new multichannel terminal was required for this service. A glance at the older type of terminal equipment shown in Fig. 1, and which currently is in standard use, will quickly show the inadequacies which led to this new design. At the start of World War II, this adaptation of the Western Electric Company type-40C1 voice-frequency carrier telegraph equipment was in use by the Army to provide up to six channels of teletype over a single radio circuit. This system is still in use and employs 2-tone frequency diversity for each channel mark and space. From Fig. 1, at least one major conclusion is apparent: the ten bays of equipment are quite a space outlay for six 60-words-per-minute (wpm) teletype channels. Also, the equipment is by no means adaptable in regard to temperature and humidity. It is essentially commercial-type, fixed plant gear, and must be treated as such if it is to perform properly.


During the '15th Intertextile Shanghai Apparel Fabrics 2009', held in Shanghai New International Expo Centre from October 20th to 24th, 2009, Italian Trade Commission - I.C.E. organized the Italian Pavilion to


In the course of performing risk assessments for several hazardous waste sites, we identified a potential for volatile organic compounds (VOCs) to migrate from a source, such as a landfill or contaminated groundwater plume, into the basements of nearby houses. VOCs can migrate through the soil, in the form of vapor, or be carried with other gases, such as methane, over considerable distances from the source of contamination. The objective of this paper is to show that I. The migration of VOCs to basements may, under some circumstances, be a significant exposure pathway for potentially harmful chemicals. 2. If the exposure pathway is possible, basements represent the point of exposu[e that will present the highest potential risk because they are the point at which VOCs will enter the house. The basement is the part of the house deepest in the soil and allows for buildup of VOCs because of low air flow. Exposure may also be possible in other areas of the house. 3. Different exposure assumptions should be considered in the risk assessment process when evaluating the significance of this exposure pathway. These include, exposure frequency (the number and length of times spent in the basement), inhalation/body weight ratio (children have a higher respiration rate and lower body weight), and toxicity of potentially harmful chemicals. 4. The detection limit for a specific VOC in basement air must be carefully considered to ensure that this limit is adequate to assure that the concentration detected presents an insignificant risk for that chemical. 5. Monitoring for a surrogate gas rnay.in some cases, be a cost-effective method for evaluating potential risk from a more potent VOC. 6. A degree of uncertainty exists with the risk assessment process. Using Monte Carlo analysis, we can quantify the way individual assumptions and uncertainties combine in exposure and subsequent risk algorithms. Data presented in this paper are from two hazardous waste sites where chemical concentrations were either modeled or measured in basements of houses located near the sites.


In this paper, a robust hierarchical method for trajectory tracking control of a quadrotor unmanned aerial vehicle (UAV) subjected to parameter uncertainties and external disturbances is presented. A robust control scheme based on a fast nonsingular terminal sliding mode strategy is designed to achieve fast response and excellent tracking accuracy. Moreover, a radial basis function artificial neural network with online adaptive schemes to estimate unknown aerodynamic parameters and external disturbances is developed to improve the control performance and reduce the chattering phenomenon. Numerical simulation and experimental results are used to validate the effectiveness of the proposed control method.


"Seasonal" is a 2D game with platformer and single player genres. This game can be played on the web or devices that can access the browser. Game is developed using Unity 2019.4.14f1. Players are required to collect 4 treasure boxes from 4 seasons. Those seasons are Spring, Summer, Autumn and Winter. Testing is done by blackbox testing, alpha testing and beta testing. Alpha testing is tested by the supervisor while beta testing is tested by 48 respondents. The results of beta testing show that "Seasonal" is a game that can be enjoyed by all groups from teenagers to adults. "Seasonal" also playable on Google Chrome, Microsoft Edge, Safari, and Opera browsers. In addition, "Seasonal" has interesting gameplay but has level of difficulty between normal to difficult.


Traditional anterior repair/colporrhaphy usually with Kelly's sutures has been used since 1914 for the vaginal repair of cystocoele and stress urinary incontinence respectively. Similarly, posterior repair or colporperineorrhaphy is the procedure of choice for vaginal rectocoele. However, both procedures are only useful for central cystocoele/ rectocoele, i.e., a central defect in the pubocervical fascia / rectovaginal septum respectively, not a lateral cystocoele/paravaginal defect, i.e., a unilateral/bilateral detachment of the pubocervical fascia / rectovaginal septum from the arcus tendineus fascia pelvis/'white line'.


In this paper, a low radar cross section (RCS) patch antenna is proposed, which is realized by engineering dispersion property of metamaterial absorbers (MAs). The dispersion curve of the MA consists of a weak linear regime with low insertion loss and an asymptotic nonlinear regime with strong absorption. By changing geometric parameters, the dispersion property of the MA can be engineered, so that the cutoff frequency is shifted freely, as well as the strong absorption band being changed. Thus, if the cutoff frequency of the MA is very close to the upper bound frequency of a patch antenna, the patch antenna will obtain polarization-independent low-RCS property out-of-band or in-band cross-polarized and out-of-band copolarized low-RCS properties by replacing the radiation patch with the modulated MA. For verification, a <inline-formula> <tex-math notation="LaTeX">${C}$ </tex-math></inline-formula>-band patch antenna with RCS reduction performance in <inline-formula> <tex-math notation="LaTeX">${X}$ </tex-math></inline-formula>-band is designed, fabricated, and measured. Both the simulated and measured results agree well and verify that the antenna achieves average gain about 5 dB in 7.2–7.7 GHz. To assess the RCS reduction performance of the proposed patch antenna, we fabricated a <inline-formula> <tex-math notation="LaTeX">$5 \times 5$ </tex-math></inline-formula> antenna array. The measured results indicate that monostatic RCS of the array is decreased by more than 10 dB in the entire <inline-formula> <tex-math notation="LaTeX">${X}$ </tex-math></inline-formula>-band for copolarized and cross-polarized wave normal incidence than the metallic plate with the same area.


In order to improve care quality of the patients with aortic dissection after the operation of Percutaneous Stents Endovascular,achieve the best therapeutic effect,nursing staffs must insist on taking patient as the center,the surgeon as the axis,nursing quality as core,understand patient illness in detail before the operation,and take the effective psychological intervention and comprehensive and efficient preparation.During the intra-operative and postoperative,nurses must make full use of safety,efficiency and warm care concepts and technologies to assure the patient to recover as soon as possible.


The photochemical reaction of photodynamic therapy (PDT) depends on the presence of molecular oxygen. Because of anoxic regions in tumor tissue and vascular shutdown during PDT, the efficiency is limited. Therefore, the use of hyperbaric oxygen, which increases the oxygen in tumor tissue, as well as the amount of singlet oxygen, may enhance the efficiency of PDT.


The paper deals with scattering problems where inhomogeneous bodies are embedded within planarly layered uniaxial media and made to interact with given sources.


The squash was pollinated during the flowering day to study the effect of pollination time on the seed number and quality.The results show that the highest seed number per fruit is obtained when the seed fruit is pollinated at about 8:00 a.m.The difference in seed number is not significant when the squash is pollinated at 10:00 a.m and (6:00 )a.m While the difference is Significant when pollinated at 12:00 noon.The seed number is the smallest whis pollinated at 12:00 noon.But the biggest seed thousand-grain weight is obtained when the seed fruit is pollinated at about 12:00 noon.There exists no significant difference in thousand_grain weight of squash seed among pollination time,6:00 a.m.;8:00 a.m.and 10:00 a.m., As far as the rate of seed germination,the tendency of seed germination and the vigor index of the seed are concerned,the seed fruit pollinated at about 6:00 a.m. is the highest; while the seed fruit,pollinated at 12:00 a.m., is the lowest. There is no significant difference among 6:00 a.m., 8:00 a.m.,and 10:00 a.m.,It can conclude that the optimum time for artificial pollination is from 6:00 to 8:00 a.m.


Based on the analysis of changes in the atomic legislation of individual foreign countries, the article identifies trends in the development of legal regulation of the introduction of new technologies in the field of atomic energy use and concludes that they go beyond the traditionally conservative culture of nuclear energy and require new incentives and approaches to their regulatory and legal regulation, developed through dialogue between regulators, the nuclear industry and science.


The problem in the present investigation was undertaken to study the tolerance of fungicide (Balyton) by the rhizosphere mycoflora of Capsicum annuum L. Tolerance of Balyton by the rhizosphre microflora of chilli was studied by serial soil dilution plate count technique. Altogether 16 fungal species were recorded from rhizosphre and soil. Out of 16 fungal species, 14 were from the rhizosphere (R) where as 11 were from soil (S). Most of the fungal species tolerated Balyton from rhizosphre and soil. Aspergillus niger and Fusarium oxysporum tolerated Balyton at higher concentration.As the fungicidal concentration increases in the plates, the fungal population decreases.


The advantages of lithium systems are described and a general summary of their application in present and future NASA programs is presented. Benefits of the lithium systems include an increased payload weight and an increased cost effectiveness to the customer. This also allows for more flexibility in the design of future space transportation systems.


Objective To explore the role of c-Jun N-terminal kinase(JNK)in the apoptosis induced by apoptin gene in human melanoma cell A375.Methods The human melanoma A375 cell was transient transfected by pcDNAA3 plasmids which contain apoptin gene,and apoptosis was measured with flow-cytometry and JNK level was detected with Western blotting and analyzed with microimage analysis system at various transfected time.Results Apoptin mRNA could ce detected by RT-PCR in melanoma cells 24h after transfection.The apoptin gene could induce apoptosis of human melanoma A375 cells in vitro 48h after transfection,the number of the apoptic cells was increased as the prolongation of the transfected time.The phosphorylated JNK was expressed 24h and reached peak level 48h and 72h after transfected with pcDNAA3.Conclusion Apoptin gene can induce apoptosis in human melanoma cell A375,and JNK could play an important role in the apoptosis induced by apoptin gene in vitro.


A new Netherlands-based initiative intends to certify mediators' training, qualifications, and general fitness for the work they do. The International Mediation Institute is soliciting comments this month on its proposed standards. Regular Alternatives contributor Judith Meyer, of Haverford, Pa., is an officer of the commission overseeing the efforts, and describes why the effort is underway and what it hopes to accomplish.


The RCN has responded to the latest national figures on female genital mutilation (FGM), saying more school nurses are needed to tackle the problem.


ABSTRACT This paper introduces some key theoretical and methodological developments in the study of intergenerational family relations. It draws on observations that a number of social issues are emerging that have an intergenerational dimension, that there is growing recognition that to study adult ageing one has also to study intergenerational relationships, and that a new architecture for social relations is beginning to take shape in the wake of demographic change. How individuals, families and societies cope with such changes provokes the question of how gerontologically-informed research, theorisation and policy will also adapt. Seven positions are summarised which attempt two things. First, to map out some new conceptual directions for intergenerational research through a critical use of concepts such as transition, generational self-awareness and empathy, metaphors of cultural translation, and the deployment of social and moral capital. Second, to examine changing gender roles, the balance between family and welfare-state support frameworks, ethnicity and immigration as important elements of this process. A critical review of approaches to intergenerational relationships hopefully emerges.


In the fast time-varying channel, there exists interference among subchannels for the orthogonal frequencydivision multiplexing (OFDM) system. The problem of intersubchannel interference (ICI) also appears in the single-carrier (SC) block transmission with frequency-domain equalization (FDE). There are several ICI reduction algorithms for the OFDM system, and some of these algorithms can be applied in the SC-FDE system. On the other hand, unlike the scenario of carrier-frequency offset, the ICI caused by the time-varying mobile channel cannot be completely removed, and the residual ICI exists after the ICI reduction. In this paper, we analyze the effect of residual ICI. We show that the impacts of the residual ICI on the OFDM system and the SC-FDE system are quite different. For the SC-FDE system, the residual ICI incurs the "error rising" when we detect the time-domain symbols after the frequency-domain equalization. The error-rising effect is worse than the error-floor effect. To avoid the error-rising effect caused by the residual ICI, one can apply the maximumlikelihood (ML) detection, or its complexity-reduced schemes, like the K-Best algorithm. The simulation results verify our analysis. Keywords— OFDM, ICI, SC-FDE


Norbert Wiener, the inventor of cybernetics, was sidelined by the U.S. government as a powerful critic of how that science was being used. His deep concerns about how the social sciences, which he considered to be a part of cybernetics, were deployed to assault the Cold War population were by-and-Iarge silenced. His worries about the massive disruptions ahead, driven by how automation would displace workers, were based on his personal observation that very few were willing to think through the social impact of technology. As a result, he organized what he called the "Genius Project" to provide historic guidance to those who might return to these concerns in some future renaissance.


The application of the Plasma Rich in Fibrin (PRF) in dentistry, provides a great advantage with comparable and positive results, since it is an autologous element, obtained from the patient's blood, through a simple, economical and fast process. This plasma includes several biological properties such as growth factors for bone regeneration. The objective of this work was to perform a literature review and update in relation to the application of PRF to better understand its properties, clinical applications and protocol in defects bone regeneration at the periodontal level. Through the bibliographic search method carried out in the primary databases such as Google Scholar, PubMed, SciELO, ScienceDirect, Dialnet, where a total of 137,000 articles were obtained; once the corresponding filters were applied, 115 articles were arrived at and, through the Average Count Citation (ACC), a final result of 78 articles was obtained as a population sample, which was used in this research. In conclusion, according to the articles studied, PRF is an excellent regenerative factor either acting alone or with bone replacement unlike other platelet concentrates (PC). However, in tissue healing it acts as a coadjuvant, but not in a way unique and direct for regeneration as such; this product presents in its fibrin mesh a stronger and denser concentration of the transforming growth factor as well as the growth factor derived from platelets, the primary biological properties that allow to improving bone restitution.


This study aimed to predict the Self- Efficacy to Deal with the Problems based on the dimensions of hope and mental well-being of students. The research method was descriptive-correlation. The statistical population included all students of the Islamic Azad University in Iran, which was equal to 14,100 people (7470 boys and 6630 girls) in the academic year 1396-97. Statistical sample According to Cochran's formula, 374 people (196 boys and 178 girls) were select by stratified random sampling. Data collection tools were standard questionnaires of Self-Efficacy to Deal with the Problems, Schneider's hope (2002), and mental well-being. The content validity of questionnaires, according to the experts and their reliability was confirmed by Cronbach's alpha test of 0.87, 0.84, and 0.84, respectively. Descriptive and inferential statistics (Pearson correlation tests and multivariate regression analysis) was use to analyze the data. The dimensions of mental well-being (positive and negative emotional well-being, psychological well-being, and social well-being) predicted 44.6% of the variance of self-efficacy in coping with problems (P≤0.05). Students who have high hopes and mental well-being have higher Self- Efficacy to Deal with the Problems.


A selection system for hybrids by protoplast fusion between Chaetomium cupreum and C.globosum using dominant selective drug resistance markers were developed.C.cupreum was sensitive to G418(G~s) and resistant to hygromycin B(H~r).C.globosum was sensitive to both G418(G~s) and hygromycin B(H~s).Agrobacterium tumefaciens mediated neomycin phosphotransferase II gene transformation of C.globosum(G~s,H~s) acquired resistance to G418 strains(G~r,H~s).Protoplasts of C.cupreum(H~r,G~s) and C.globosum(H~s,G~r) were prepared,mixed in the presence of polyethylene glycol 6000 and incubated on regeneration agar plates.Two regenerated colonies showing H~r and G~r were regarded as hybrids by amplified fragment length polymorphisms analysis of the genomic DNA and they displayed a significant exchange of taxonomic characteristics between the parental strains.


This study analyzed literary works and references related to Dok-Rak-Dang(獨樂堂) and the attributes of managing the landscape in Dok-Rak-Dang Garden based on the assumption of position and the spatial structure revealed in the site. Hoe-Jae Lee Eon-Jeok(1491-1553), a distinguished scholar of Neo-Confusionism, built Dok-Rak-Dang and managed the surrounding areas during his retirement years. He called the mountains, stream, and rock along and near the Ja-Ge Stream Four Mountains and Five Platforms(四山五臺). Before he named these, they were not considered special. The Four Mountains which are Do-Duk in north, Mu-Hak in south, Hwa-Gae in east, and Ja-Ok in west enclose Dok-Rak-Dang and the surrounding areas. The Five Platforms, Se-Sim, Gwan-Eo, Yeong-Gue, Jing-Sim, and Tak-Yeong, in order from downstream, are places with beautiful scenery in Ja-Ge Stream. The attributes of managing the landscape in Dok-Rak-Dang Garden are the following: One is the spatial integration of what is natural and artificial as the attitude of aesthetic experience in accord with nature. Another is flexible territorialization as the way of organizing spaces in nature from the experiential aspect. The other is place making of personalized nature through a series of processes such as observing, choosing, and naming landscapes in nature. Four Mountains and Five Platforms function as landscape bases and elements to appreciate nature aesthetically. Those attributes are different from the attitude of constructing spaces. Rather, they originate from the traditional view on the appreciation of nature. Above all, place-making in nature was acquired from designed spatial structure and experiential aesthetic appreciation in the space through observing, choosing, and naming landscapes in nature reflecting creator`s own ideological and aesthetic thoughts, and it might be explained as one of practical ways of Korean traditional gardening.