The material under investigation consists of particles of relatively large conductivity embedded or immersed in a matrix, the volume fraction of the particles being so high that they are in, or nearly in, contact. The particles are arranged randomly, and the material is statistically homogeneous. A general formula gives the effective conductivity of the material in terms of the average thermal (or electrical) dipole strength of a particle. The thermal flux across the surface of a particle is concentrated in areas near points of contact with another particle, and the dipole strength is approximately equal to a weighted sum of the fluxes across the areas near contact points. It is thus necessary to calculate the flux between two adjoining particles at different temperatures, and we do this by solving numerically an integral equation for the distribution of temperature over the (locally spherical) surface of one of the particles near the contact point. The flux between the two particles is found to be proportional to loge ah when a2 2h/a≫ 1 and to loge a when a 2h/a≪ 1, where h is the minimum gap between the particle surfaces, a~1 the mean of their local curvatures, and a the ratio of the conductivities of the particles and the matrix. In the case of two particles pressed together to form a circular flat spot of radius p, the flux occurs almost wholly in the particle material, and is proportional to p when ap/a≫ 1. Explicit approximate results are obtained for the effective conductivity of the granular material in the case of uniform spherical particles. For a close-packed bed of particles making point contact the effective conductivity is found to be 4.0k logea where k is the matrix conductivity. This asymptotic relation (applicable when a ≫ 1) is seen to be consistent with the available measurements of the conductivity of packed beds of spheres. Values of the effective conductivity for packed beds of particles of different shape are not expected to be greatly different.


This paper intends to study the representation of history and the unique narrative strategy of Hou Hsiao-Hsien's film A City of Sadness. Dealing with the Taiwanese history between 1945 and 1949, A City of Sadness is pioneering in bringing the 2.28 accident in 1947 to the film. But it shows some historical inaccuracy of including the LuKu accident in 1950 within its narrative of the 2.28 accident in 1947. A City of Sadness is characteristic of using various media in the narrative. For instance, subtitle, writing conversation, music, broadcasting, and blood writing make the film original. And the film contrasts the male ruler's authoritative voice from broadcasting with the lyrical female narrative in the modes of diary and letter. It suggests not only the sexual difference between man and woman but also a relation between official memory and popular memory. In this film the revolutionary aspect of the 2.28 accident is not highly emphasized. It is due to the director's inclination to cherish the ordinariness and continuity of life, which shows Hou Hsiao-Hsien's own respectful style.


The utility model relates to a safety belt for a high-voltage overhead line operation, belonging to safety devices for operation in an electrical power system. The safety belt comprises a belt and is characterized in that an insulating rope and a limit ring are arranged on the belt, and the insulating rope is sewn on one side of the belt and is fixed on the belt by the limit ring. According to the safety belt for the high-voltage overhead line operation, disclosed by the utility model, an operator can effectively hang operation tools on the waist by utilizing the safety belt till finishes the operation and falls on the ground, and the safety belt is always arranged on the body of the operator, thus a purpose of safety operation is realized.


A channel estimation technique which allows the support of higher terminal velocities in OFDM based WLANs (HIPERLAN/2, IEEE 802.11a) is presented. After an initial channel estimation based on the preamble, the channel impulse response is tracked by means of detected and remodulated data symbols. A good performance is obtained in both line-of-sight (LOS) and nonline-of-sight (nLOS) environments with a reasonable receiver complexity.


The era of the democratic sabbatical (1868-1874) was particularly rich in political events and theatrical life was very intense. Politically committed playwrights took advantage of the situation as well as a new freedom of expression to transfer current topics such as Revolution, choice of political system, different possible monarchs, republic and such, to the theatrical stage. They expressed their opinions and their hopes or exposed corruption and tried to provoke debate and political choice among the audience who could participate in political decisions thanks to the universal suffrage just adopted.


The ratio of Yttrium (Y) to Praseodymium (Pr) is varied in (Y/sub x/Pr/sub 1-x/)Ba/sub 2/Cu/sub 3/O/sub 7-/spl delta// (YPBCO) thin films to consider the relation between superconducting YBa/sub 2/Cu/sub 3/O/sub 7-/spl delta// (YBCO) and insulating PrBa/sub 2/Cu/sub 3/O/sub 7-/spl delta// (PBCO) thin films. The critical temperature (T/sub c/) of the superconducting YPBCO thin film is decreased by substituting more Pr in place of Y, because Pr reduces the carrier density on the CuO/sub 2/ plane in YPBCO. The electrical characteristic of the YBCO film can be explained by the weakly coupled chain model. The addition of Pr reinforces the superconducting links among the grains in the YPBCO thin film. The normal state YPBCO film-shows two types of transport systems. Behavior similar to impurity semiconductors appears at high temperatures and the variable range hopping mechanism governs their conductance at low temperatures.<<ETX>>


Rattle noise occurs at manual transmission as idling and driving of a automotive. It can be solved by torsional characteristics of a clutch disc. A clutch disc consist of a region of pre-damper and main-damper. Rattle noise is affected by pre-damper and main-damper equipped for a torsional spring and friction washer. Pre-damper range covers noise radiating from manual transmission when engine is idling and main-damper range covers noise when engine is driving. The aim of this reserch is to clear transmission rattle noise by way of torsional characteristics of a clutch disc. The experiment is carried out as idling and driving of a automobile equipped for 1.5L MPI engine, dry single-disc type clutch and manual transmission. In this study, the results show for a vibration of manual transmission as idling and driving can be cleared by a clutch disc of Pre-damper type.


The different representations of the topographical features of Sydney Cove as drawn by Thomas Watling and as painted by Edward Dayes, based on Watling's drawings are analysed, highlighting their different picturesque aesthetic in picturing a sense of place. Watling's drawings are stark reproductions of Sydney Cove, while Dayes' paintings add to or obscure something from his drawings in order to make it an artistic representation of the place.


The features of optical radiation interaction with surface of gratings are investigated. The diffraction grating is proposed to be used in the effective medium model to test nanostructured surfaces. This object allows obtaining simultaneous visualization of different spatial frequencies and estimation of both structure and surface features of 3D-objects. It was shown that the effective medium model could be used to predict the reflectivity of nanostructured surfaces by using diffraction gratings with different depths of profile. Computer simulations show that the filling factor of composite systems could be an angle dependent function. So, the correct solution of the inverse problem of finding surface characteristics, such as refraction indices and absorption coefficients, is related with the angle dependence of filling factor.


Cytokine secretion and degranulation represent key components of CD8+ T‐cell cytotoxicity. While transcriptional blockade of IFN‐γ and inhibition of degranulation by TGF‐β are well established, we wondered whether TGF‐β could also induce immune‐regulatory miRNAs in human CD8+ T cells. We used miRNA microarrays and high‐throughput sequencing in combination with qRT‐PCR and found that TGF‐β promotes expression of the miR‐23a cluster in human CD8+ T cells. Likewise, TGF‐β up‐regulated expression of the cluster in CD8+ T cells from wild‐type mice, but not in cells from mice with tissue‐specific expression of a dominant‐negative TGF‐β type II receptor. Reporter gene assays including site mutations confirmed that miR‐23a specifically targets the 3′UTR of CD107a/LAMP1 mRNA, whereas the further miRNAs expressed in this cluster—namely, miR‐27a and ‐24—target the 3′UTR of IFN‐γ mRNA. Upon modulation of the miR‐23a cluster by the respective miRNA antagomirs and mimics, we observed significant changes in IFN‐γ expression, but only slight effects on CD107a/LAMP1 expression. Still, overexpression of the cluster attenuated the cytotoxic activity of antigen‐specific CD8+ T cells. These functional data thus reveal that the miR‐23a cluster not only is induced by TGF‐β, but also exerts a suppressive effect on CD8+ T‐cell effector functions, even in the absence of TGF‐β signaling.


This paper puts forward a research agenda in the area of explicit and implicit knowledge and learning of second or additional languages. Based on a brief overview of reliable findings as well as open questions in the field, three agenda items are highlighted. First, valid and reliable measures of explicit and, in particular, implicit knowledge and learning need to be identified and their suitability for participants of different ages established. Second, and closely related to the previous point, explicit and implicit knowledge and learning should be investigated across the human lifespan. Therefore, studies need to include to a greater extent hitherto under-represented groups such as children and older adults in order to pinpoint the benefits or otherwise of implicit and, in particular, explicit knowledge and learning in these age ranges. Third, researchers should aim to capture with their designs the complex and dynamic interplay of the multiple cognitive, affective, biographical and contextual factors that influence the development of explicit and implicit knowledge over time. Concrete tasks for future research are proposed under these three agenda items, with a view to assisting interested investigators in formulating research questions and specifying research designs.


In this study, we propose a multistart method based on an extended version of the Hooke and Jeeves (HJ) algorithm for computing multiple solutions of mixed variable optimization problems. The inequality and equality constraints of the problem are handled by a lter set methodology. The basic ideas present in the HJ algorithm, namely the exploratory and pattern moves, are extended to consider two objective functions and to handle continuous and integer variables simultaneously. This proposal is integrated into a multistart method as a local search procedure that is repeatedly invoked to converge to dierent global and non-global optimal solutions starting from randomly generated points. To avoid repeated convergence to previously computed solutions, the concept of region of attraction of an optimizer is implemented. The performance of the new method is tested on benchmark problems. Its


A Woman with Delusional Thinking and Paresthesia A 48-year-old woman presented with tingling of the right hand and was found to have disorganized and delusional thinking. Laboratory evaluation reve...


We present an analysis method that provides tight temporal bounds for applications modeled by Synchronous Dataflow Graphs and mapped to shared resources. We consider the resource sharing effects on the temporal behaviour of the application by embedding worst case resource availability curves in the symbolic simulation of the application graph. Symbolic simulation of the application results in a (max, +) characterization matrix. This matrix specifies a set of recursive linear equations in (max, +) algebra that bound the worst case execution of the application. We obtain tighter temporal bounds on the completion times of tasks than state of the art analysis. This is achieved by improving the response times of the tasks by identifying possible consecutive task executions on the resources. This enables us to use accumulated response times which are less pessimistic. Applying the new approach to real-life applications gives significant improvements over the bounds compared to state of the art.


Patch reefs within the Mural Limestone (Bisbee Group, Cretaceous, S. E. Arizona) are dominated by scleractinian corals, algal stromatolites, and rudist bivalves. Reef development occurred during the Early Albian transgression into the Chihuahua Trough, a north-west extension of the Tethyan seaway. One patch reef (270 m x 120 m) was studied in detail. Species abundance and growth form were estimated in each of 57 quadrats of l m2 along ten transects. Peels and slabs were used for detailed identification and for lithologic determination. Facies development is controlled by wave energy. The crescent-shaped front is dominated by branching and mas sive corals. Behind this fades a zone of laminar Microsolena (coral) along with algal stromatolites form the crest facies. Rudists dominate the back reef. The Petalodontia subfacies is closest to the reef crest and consists of thickets of gregarious, thick-walled Petalodontia, a few corals, and interbedded molluscan debris. The caprinid subfacies is farthest from the reef crest and contains corals, bivalves, and molluscan fragments. A debris facies of molluscan fragments and foraminifera surrounds the reef. Reefs of roughly correlative age in Texas are dominated by rudists, not corals. The Texas rudist frameworks are often associated with evidence of abnormal salinity conditions which were presumably intolerable for corals.


This is a guide to standard resources for introductory study or review of western art music, jazz, popular music, and world music.


Three conventional tillage methods combined with two fertilizing levels were compared using two different maize and sorghum hybrids in terms of yields and quality yields parameters (test weight and 1000-kernel weight). Autumn plow and N120P70 fertilizing treatment determined the higher yields and quality parameters values for both maize and sorghum. Fertilizing treatment with N120P70 lead to significant yield increases with 11-19 q/ha for maize and 8 q/ha for sorghum. On three years average the best yield results were recorded by Partizan (maize hybrid) and Fundulea 21 (sorghum).


This paper analyses the deficiency of voltage and reactive-power control in Guangzhou electric power network,and describes the structure,principle, development process,difficulty in technology and application of the distributed voltage and reactive-power control system based on global optimization which is independently developed by Guangzhou Power Supply Branch,GPG and is satisfactorily applied in Luming power network.This system consists of main station system,voltage and reactive-power real-time control subsystem(VQC)and communication subsystem.The control range of voltage and reactive-power control subsystems can be obtained according to global discrete reactive-power optimization, and hence global voltage and reactive-power optimization and distributed real-time control can be realized.


This paper reviews the optimization strategies for the optimal simultaneous allocation of distributed generation (DG) and shunts capacitor banks (SCBs) in electrical distribution networks. These optimization strategies aim to determine the optimal size, location, and combination of DGs and SCBs to constitute a techno-economic system while satisfying the constraints and energy demand of the load. The optimization strategies explicitly reviewed include the problem formulations, optimization techniques, restrictions posed for optimization problems, decision variables, and network operating modes typically assumed while allocating the DGs and SCBs. In addition, there is an attempt to highlight the limitations of the existing literature and future research directions. This study undertakes a comprehensive review of the literature that systematically considers the simultaneous application of DGs and SCBs to advance the existing literature, which lacks such a review. Expectedly, this review will serve as a principle platform for researchers intending to explore the subject area for further improvement.


Posture analysis in quiet standing is an essential element in evaluating human balance control. Many factors enhance the human control system's ability to maintain stability, such as the visual system and base of support (feet) placement. In contrast, many neural pathologies, such as Parkinson's disease (PD) and cerebellar disorder, disturb human stability. This paper addresses the problem of the automatic segmentation of stabilometric signals recorded under four different conditions related to vision and foot position. This is achieved for both control subjects and PD subjects. A hidden Markov model (HMM)-regression-based approach is used to carry out the segmentation between the different conditions using simple and multiple regression processes. Twenty-eight control subjects and thirty-two PD subjects participated in this study. They were asked to stand upright while recording stabilometric signals in mediolateral and anteroposterior directions under two permutations: feet apart and together with eyes open or closed. The results show high values for the correct segmentation rates, up to 98%, for the separation between the different conditions. The present findings could help clinicians better understand the motor strategies used by the patients during their orthostatic postures and may guide the rehabilitation process. The proposed method compares favorably with standard segmentation approaches.Note to Practitioners—In this paper, the problem of human balance control assessment is analyzed through the segmentation of the multidimensional time series of the center of pressure (CoP) displacement measurements during orthostatic postures of healthy and Parkinsonian subjects. The proposed model for automatic temporal segmentation is a specific statistical latent process model that assumes that the observed stabilometric sequence is governed by a sequence of hidden (unobserved) states or conditions. More specifically, the proposed approach is based on a specific multiple regression model that incorporates a hidden Markov process that governs the switching from one condition to another over time. The model is learned in an unsupervised context by maximizing the observed data log-likelihood via a dedicated expectation–maximization algorithm. We applied it on a real-world automatic CoP displacement excursion segmentation problem and assessed its performance by performing comparisons with alternative approaches, including well-known supervised static classifiers and the standard HMM. The results obtained are very encouraging and show that the proposed approach is quite competitive, though it works in an entirely unsupervised fashion and does not requires a feature extraction preprocessing step. The present findings could help clinicians to better understand the motor strategies used by the patients during their orthostatic postures and may guide the rehabilitation process.


Single-crystal X-ray diffraction studies are among the best experimental methods for elucidating the structure of chemical compounds. Recently, their focus has been shifted towards extracting information on chemical bonding features and related valuable properties of these compounds from the analysis of charge density distribution obtained in high-resolution X-ray diffraction experiments; the latter are possible only for a limited number of well-ordered crystals of small molecules. In this review, the hybrid approaches are described that introduce quantum chemical methods into the refinement of X-ray diffraction data. Their use significantly extends the range of systems suitable for charge density studies (such as polypeptides, metal-organic frameworks, inclusion compounds and others) and the scope of problems that they solve, viz., from protein structure refinement to determination of thermodynamic or other wave function-derived properties of crystals. The potential of these hybrid approaches and prospects for their future applications are discussed. The bibliography includes 322 references.


Real-money trade (RMT) of virtual assets in MMO:s is a large phenomenon. Many studies have analysed how RMT affects the game, but few have asked and discussed with players how they feel about RMT. Many different games have been analysed in earlier studies but we have chosen to analyse the game World of Warcraft (WoW) because of its popularity and the large presence of RMT in this game.In this study gamers from WoW have been given the chance to express their opinion about how RMT affects the game and how they believe that RMT should be handled in MMO:s.


In his immensely provocative work The Power Elite, Mills argued that the United States of America is controlled and manipulated by elite that constituted the leadership of three major institutions: business, government, and the military. These institutions and their leaders, over the years, have consolidated their hold on power while evading public opprobrium and chasm. Although Mills and those who support his thesis have been successful at applying the "power elite" model to the United States and, perhaps, developed countries in the Western hemisphere, it is debatable that his rigid classifications and their underlying assumptions apply to other countries, particularly in Africa with different socio-cultural, political, economic, and historical milieu. This article offers an opportunity to apply the "power elite" model to a non-Western, underdeveloped modern nation-state: Nigeria. Nigeria, the most populous Black nation on earth, is clearly under the control of a "power elite." The question is which elite? Within relatively brief compass, I attempt to identify the Nigerian power elite as a way to validate or reject the "power elite" model of C. Wright Mills.


This work investigates the generation of information by public-interest civil society organizations (organizacoes da sociedade civil de interesse publico, or OSCIPs) that operate with microcredit to support their accountability, and the use of this information in analyzing their financial performance. In the process of building up scientific knowledge for this work, an exploratory study was conducted of organizations of the third sector, focusing on public-interest civil society organizations that provide microcredit and the information they use to render accounts and evaluate their performance. It is an exploratory work, guided by bibliographical and documental research and a multi-case study carried out through an interview assisted by a semi-structured checklist, whose data were then treated through the technique of content analysis. The conclusion is that albeit still incipient, the microcredit organizations studied seek to measure their performance and act in a transparent manner, including meeting the requirements of the agents that provide their funding, and that this openness is a differential in obtaining new funding.


Consider an assignment of bits to the vertices of a connected graph <inline-formula> <tex-math notation="LaTeX">$G(V,E)$ </tex-math></inline-formula> with the property that the value of each vertex is a function of the values of its neighbors. A collection of such assignments is called a storage code of length <inline-formula> <tex-math notation="LaTeX">$|V|$ </tex-math></inline-formula> on <inline-formula> <tex-math notation="LaTeX">$G$ </tex-math></inline-formula>. The storage code problem can be equivalently formulated as maximizing the probability of success in a guessing game on graphs, or constructing index codes of small rate. If <inline-formula> <tex-math notation="LaTeX">$G$ </tex-math></inline-formula> contains many cliques, it is easy to construct codes of rate close to 1, so a natural problem is to construct high-rate codes on triangle-free graphs, where constructing codes of rate <inline-formula> <tex-math notation="LaTeX">$> 1/2$ </tex-math></inline-formula> is a nontrivial task, with few known results. In this work we construct infinite families of linear storage codes with high rate relying on coset graphs of binary linear codes. We also derive necessary conditions for such codes to have high rate, and even rate potentially close to one. We also address correction of multiple erasures in the codeword, deriving recovery guarantees based on expansion properties of the graph. Finally, we point out connections between linear storage codes and quantum CSS codes, a link to bootstrap percolation and contagion spread in graphs, and formulate a number of open problems.


Cotton production continues to require the application of a range of registered pesticides and herbicides. However, the introduction of transgenic cotton, resistant to insects (Ingard®) or herbicides (Roundup Ready® Cotton), with integrated pest management, has provided Australian cotton farmers with more options regarding responsible crop protection. These are supported by the development of methods of risk assessment for pesticides, monitoring for their residues and the application of practical remedies. In the first approach, knowledge of the physical and chemical properties of chemicals and of their environmental fate allows estimates of relative risk from different pesticides. Factors of importance in conducting such an assessment include relative distribution into different environmental compartments (e.g. Koc, Kow), volatility, solubility in water, half-life and biodegradation, and toxicity of products. Such assessments can indicate the likelihood of residue risk in cottonseed or of grazing livestock from aerial drift. The second approach, monitoring of pesticide residues, has the important role in providing feedback regarding the fate of pesticides and for validation of risk modeling. Thirdly, the Australian cotton industry has experienced several crises regarding the contamination of livestock for export. In response, best management practices have been developed, supported by the results of research conducted for the cotton industry in the decade 1991-2001. We have also developed a new methodology for assessing the ecological risk of chemicals used in Australian cotton production. A case study of risk in proposed extensions in the area sown to cotton was used as a model that could be applied to other farms under development. Based on a standard framework for ecological risk assessment (ERA), this methodology integrates the exposure and toxicity of an agro-chemical to estimate its risk to a specific environment. To determine the exposure, the use of existing models (e.g. the fugacity model) proved to be the most affordable way to calculate concentrations of pesticides in several environmental compartments. Knowing the dissipation rates (half-lives) of a chemical, its concentration with time can be estimated for each compartment in the model. Thus, the probability of exposure of chemicals applied on farm can be estimated for both the spatial and temporal dimensions. Individual characteristics of a particular cotton farm, such as its location with respect to sensitive ecosystems, farm layouts, climatic conditions, and the pest management program, are taken into account. Other remedies for reducing the risks from use of pesticides are proposed, including better farm design, reduction of drift and the use of constructed on-farm wetlands.


Clinic. Journal number 11 for 1901
The author describes two cases of primary filmy lesions of the larynx without Lffler's sticks, tested on a sectional table, in both cases, repeated (during life and after death) bacterioscopic and microscopic investigations of a case of the larynx were performed, both cases were partially treated.


Executive agencies are not the only entities generating websites and using other information technologies. The judicial branch is also making progress toward developing better portals to improve their processes and strengthen the relationships with citizens and other stakeholders. In fact, most judicial agencies have created their own websites with different levels of technological sophistication and functionality. However, very little is known about the structure, usability, content, and impacts of these websites. Based on previous research developed in 2010, this study proposes a framework to measure and evaluate judicial websites and performs a pilot test of the instrument in 20 states in Mexico. Implications for research and practice are derived and ideas for future studies are also suggested.


Thiamin, a water-soluble vitamin, is present in considerable amounts in meat, cereals, legumes and, in smaller amounts, in milk. It is well known that heating affects the thiamin content of foods. Heat treatments of milk such as sterilization or ultra high temperature (UHT) that achieve a long shelf life cause losses of thiamin (Renner, 1989). The domestic use of microwave ovens to heat different foods has been widely extended during recent years. However, no information has been reported on the effect of this type of heating on the retention of thiamin in milk. Milk sterilization has also been carried out by microwave heating in pilot installations and could be in extensive commercial use in the next few years (Mudgett, 1989). In the work reported here we have studied the effect of microwave heating on the thiamin content of milks using two different conditions and three levels of fat.


Hydrological properties of the groundwater system which might have affected the occur-rence of the large scale landslide near the Shigeto Station on the Dosan Line of the JapaneseNational Railways on July 5, 1972 was investigated through the continuous observation ofthe groundwater level and the discharge of a spring. The observation was started inNovember 1973 and continued until December 1976 although some interruption was involved.On this basis, it is revealed that unconfined groundwater occurs in fractured rock at thegentle ridge-type slope behind the landslide area. It stands to reason that a part of thisgroundwater was led to the spring in the landslide area through a permeable channel formedby the fracturing of rocks in the fault plane which crosses the area in question.Simulation of the groundwater system is carried out using a tank model based on thisinterpretation and is verified by comparing the result with the observed values. It thenyieds the estimation of the hydrograph of the spring at the time of the occurrence of thelandslide. It is concluded that the rainfall on July 5, 1972 whose duration was of the sameorder of magnitude with the time constant of the recharge of the groundwater system was,unfortunately, effective as a trigger for landslide though the total amount of rainfall was notso great as to be called "record-breaking".


Based on the project of Shanghai metro line 11's side-crossing the St.Ignatius Cathedral,some helpful predications and deep analysis about long-term surface settlements have been presented by employing numerical simulation approaches and in-situ measurement techniques.Furthermore,the strengthening effects of MJS piles and the complicated influences of adjacent architectures are evaluated and calculated prudently.The computation results indicate that long-term surface settlement increases gradually over time and achieves stabilization ultimately.Due to the existence of MJS piles and adjacent buildings,the settlement trough significantly differs from traditional forms and performs a remarkable asymmetry.Particularly,it should be emphasized that those MJS piles effectively protect the surrounding region from large settlements and other harmful effects.The numerical simulation results and in-situ measurement data reveal a matching physical discipline;so the method of numerical simulation is validated scientifically and reasonably.Finally,several influences which contribute to the long-term settlement are analyzed:MJS pile reinforcement,building,disturbed region and creep parameters.Obviously,the achievement in this paper would provide a valuable reference for future similar projects.


Summary: Serologic HLA typing was performed on 29 patients with infantile spasms and hypsarrhythmic patterns in their electroencephalograms (EEGs). There were no significant increases in the frequencies of HLA‐A, B, and C antigens in the infantile spasm group as compared with controls. However, there was a significant increase in the frequency of DRw52 in the infantile spasm patients (90%) as compared with controls (72%) (p < 0.05). In addition, 3 of 12 white infantile spasm patients demonstrated the complete B18, DR3 (DRw52) haplotype; none of 150 control white subjects showed this haplotype. These findings contribute to evidence that immunological mechanisms may be involved in the pathophysiology of infantile spasms.


Samples of 10 varieties of broad bean were analyzed for dry matter, crude protein, amino acids and alkaloid glucosides. The varieties "Korunde" and "Supersimonia" showed the highest protein content; the amino acid composition was similar in all varieties. Sulfur-amino acids were limiting in all tested varieties. The varieties "Gemini" and "Locale di Putignano" showed the highest content of total alkaloid glucosides. It was noticed that variety "Supersimonia", able to produce 1870 kg/ha, shows also a high protein content and a low antinutritional factor content. The results of this work supply information to the breeder about varieties with low content of antinutritional factors.


Poly( butylene terephthalate)( PBT) /liner low density polyethylene( LLDPE) blends had been prepared by using reactive melting compounding technology. In order to improve the compatibility of PBT /LLDPE blend, epoxidized ethylene-propylene-diene monomer( eEPDM) rubber was used as a compatibilizer. The effects of eEPDM on the morphologies and mechanical properties of PBT /LLDPE blends were investigated. The PBT /LLDPE blends were investigated and the phase morphology was observed by means of Fourier transform infrared spectroscopy and scanning electron microscopy. The experimental results showed that the epoxy groups of eEPDM reacted with the terminal carboxylic acid group of PBT,thus leading to the formation of PBT-g-EPDM copolymer. The PBT-g-EPDM copolymer acted as a compatibilizer between PBT and LLDPE. Compared with PBT /LLDPE /EPDM blend,a more uniform and fine dispersed phase of PBT /LLDPE /eEPDM blends was observed. Moreover,the addition of eEPDM also improved the impact properties of PBT /LLDPE blends better than EPDM.


Lisa Listyani, 2018 : The Influence of Size of Local Government and Audit Remarks on Audit Delay of Financial Government of Java Island, Indonesia in the Period 2016.
This research aims to analyze the influence of Size of Local Government and Audit Remarks on Audit Delay of Local Government in Java Island period 2016. Audit Delay is the dependent variable in this research. It was measured by total of Audit time. Meanwhile, for the independent variables using Size of local government was measure by total of expenditure of APBD and the Audit Remarks was measure by total of Remarks. This research used Secondary data with a population of Finance Government in Java Island period 2016. While sampling used census sample method, which is overall 119 local government choose. This research used multiple regression method to test hypothesis with IBM SPSS 22 Version program.
The result of this study show that (1) Size of Local Government has a positive significant effect on Audit Delay (2) Audit Remark has positive significant effect on Audit Delay (3) Size of Local Government and Audit Remark has simultaneous significant on Audit Delay in Local Government Java Island 2016.
Keywords : Audit Delay, Audit report lag, Size of Local Government and Audit Remarks.


A 12-year-old girl had been symptomatic since the age of 8 years. She had progressive swelling and flexion deformity of both little fingers associated with restriction of movements at distal interphalangeal (DIP) joints, but no pain or early morning stiffness. On examination, she had flexion deformity and swelling at the tips of fifth hand digits (Fig. A and B). Rest of the physical examination was unremarkable. X-ray films showed shortened, sclerosed diaphysis of the terminal phalanx of fifth digits (arrows) with palmar and radial deviation of the phalanges (Fig. C and D). Differential diagnosis included tuberculosis, sarcoidosis, hyperparathyroidism, enchondrosis, epidermoid inclusion cyst, and avascular necrosis of distal phalanx. Laboratory investigations revealed hemoglobin 116 g/L, total leukocyte count 8.1 10/L (polymorphs 56%, lymphocyte 34%, monocytes 7%, eosinophils 3%), platelets 197 10/L, erythrocyte sedimentation rate 19 mm in the first hour, and C-reactive protein less than 1.7 mg/L. Urine examination showed no abnormality; serum calcium, 24-hour urinary calcium excretion, and urine calcium-to-creatinine ratio were normal. Tuberculin skin test was negative. Serology for human immunodeficiency virus was nonreactive. Ultrasound examination of local site showed normal soft tissue and tendons. Bone scan did not show an increased uptake. Fine-needle aspiration cytology from the local site revealed no abnormality. Antinuclear antibody (indirect immunofluorescence, 1:40 dilution) was negative and anti– double-stranded DNA antibody titers were normal (7 IU/mL; reference, <60 IU/mL). High-performance liquid chromatography from blood ruled out for the possibility of sickle cell anemia; procoagulant workup revealed normal levels of protein C, protein S, and antithrombin III. Antiphospholipid antibody titers were within normal limits, and there was no mutation in factor V Leiden gene. MRI showed shortened terminal phalanx of


Abstract Conventional amplitude inversion assumes that the migrated image preserves relative-amplitude information. However, illumination effects caused by complex geologic settings, undersampled acquisition geometry, and limited recording aperture pose a challenge to even the most advanced imaging algorithms. In addition, standard depth-migration images can suffer from lack of resolution caused by wavelet stretch, attenuation, and suboptimal deghosting. Least-squares migration (LSM) can mitigate many of these problems and produce better resolved migration images suitable for AVO inversion. However, whether formulated in the data domain or the image domain, LSM is an inversion algorithm and is sensitive to inaccuracies in the source wavelet, velocity model, data preprocessing, and the propagator used. Practical considerations to mitigate these problems under nonideal conditions and cost-reduction strategies differ between the data- and image-domain formulations. The relative merits of each approach are ev...


Computer program uses an iterative method to construct precisely periodic orbits which dynamically approximate solutions that converge to precise dynamical solutions in the limit of the sequence. The method used is a modification of the generalized Newton-Raphson algorithm used in analyzing two point boundary problems.


The mouse is developed with the purpose of providing reinforcement of database s ecurity for computer users, whose validity can be verified by taking advantage o f the fingerprint identity, which is the unique, immutable biological characteri stic of human body. A robust one-by-one matching algorithm, rendering between pr essured data and field acquisitions of finger print image, contributed to the vi tal heart of dactylogram verification with the mouse. The mouse has been made po ssible by taking account of the roomy space within mouse, tiny chip patch for fi ngerprint identification, together with small size of available microprocessors, The mouse can be used as an normal pointing device while maintaining the capabi lity of user identity distinguishing. The usage of this device is very easy and reliable. The purpose, principle and system design of the mouse are introduced i n this paper. The characteristics and applications of the device are also presen ted.


Small cell lung cancer (SCLC) is a tumor enriched in neuroendocrine properties including the enzymes L-dopa decarboxylase and polypeptide hormones.' In particular, high levels of immunoreactive bombesin (BN) and the structurally related gastrinreleasing peptide (GRP) are present in SCLC cell lines, tumors, and xenographs in nude mice?-' These peptides are secreted from SCLC cells6 and BN stimulates growth of SCLC cells.7 Because these peptides may function as autocrine growth factors in SCLC, the presence of receptors for BN/GRP-like peptides was investigated. SCLC cells (NCLH345) were cultured in serum-free HITES medium (RPMI1640). which contained lo-* M hydrocortisone, 5 pg/ml insulin, 10 pg/ml human transferrin, M /3-estradiol and 3 x lo-* M Na2Se0, as described previously.' Approximately 10' cells were added to HITES medium to which 0.25% BSA, 100 pg/ml bacitracin and 40,000 cpm of [L251-Tyr4]BN was added; the total volume was 200 pl. The samples were incubated for 30 minutes at 37OC and the cells were centrifuged using a Beckman microfuge B for one minute and the pellet, which contained bound peptide, was rinsed twice with 200 pl of buffer to remove free peptide. The pellet, which contained bound ['2SI-Tyr4]BN was counted in a gamma counter. Radiolabeled (Tyr4)BN bound with high affinity (Kd = 0.5 nM) to a single class of sites (1,5OO/cell). Kinetic studies indicated that ['251-Tyr4]BN rapidly associated with SCLC cells (k, = 6 x lo7 M-' min-') and equilibrium was attained after 20 minutes at 37OC. Also radiolabeled (Tyr4)BN dissociated slowly from SCLC cells after the addition of excess competitor (1 pM unlabeled BN) (k-, = 0.03 min-I) and after 90 minutes all specific binding was reversed. After a 30-minute incubation, the amourit of ['*'I-Tyr']BN bound specifically at 4 or 37OC was similar, and if cells that contained bound peptide were subsequently treated with 0.2 M acetic acid and 0.5 M NaCl (pH 2.5 at 4OC) for five minutes, 82 * 5% of the specifically bound ['251-Tyr4]BN dissociated from the cells. Also, after treatment of SCLC cells with 0.3 pM chloroquine, a chemical reagent that affects the lysosomal internalization of peptides, the kinetics of ['251-Tyr4]BN binding were unaffected. These data suggest that radiolabeled (Tyr4)BN binds to cell surface components that are not internalized. Because no specific binding remained after treatment of the SCLC cells with trypsin (50 pg/ml), radiolabeled (Tyr')BN may bind to cell surface proteins. Pharmacology studies indicated that the COOH-terminal of BN or GRP was responsible for the high-affinity binding activity. TABLE 1 shows that (Tyr4)BN was the most potent analogue tested in that the concentration of unlabeled peptide required to inhibit half (IC,) of the specific [I2'I-Tyr4]BN bound was 0.7 nM. (Ac-GRP~"~'), BN, and GRPICz7 were also potent analogues with ICso values of 1, 1.5, and 2 nM, respectively. Surprisingly GRP was less potent than the COOH-terminal octapeptide,


A mathematical model was put forward for simulating the fluid flow phenomena during mold filling of liquid metal using the finite difference method.A computational program was developed based on the SOLA-VOF algorithm for numerically calculating the 3-D fluid field during mold filling of liquid metal.Finally,by using the program,numerical calculation on fluid field during mold filling of benchmark test casting was carried out.The results of numerical simulation are similar to agree well with those of classic examples,which indicates that the program is of high precision in numerical calculation.


Optically active tiraras-cycloheximide isomers such as cycloheximide [(2S,4S,6R,αR)-form (1)], naramycin B[(25,4S,6RαR)-form(4)], and new stereoisomers (2S,4S,6S,αS)-form (8) and (2S,4S,6R,αS)-from (9) were synthesized by an aldol condensation of trans-2,4-dimethyl-l-cyclohexanone (5b), with 4-(2-oxoethyl)-2,6-piperidinedione(6). The antimicrobial activity of trans- cycloheximide isomers (1, 4, 8, and 9) was examined against S. cerevisiae and P. oryzae. The stereoisomers 1 and 4 exhibited marked antimicrobial activity against both microorganisms as compared with their C- α-epimers 8 and 9.


We have studied the influence of laser illumination on the magnetization in multiferroic YbFe2O4 single crystals. A photoinduced magnetization change has been confirmed in both ab plane and c axis direction. The temperature dependence of the photoinduced magnetization reduction excludes laser heating as the cause. In terms of the breakdown of charge order driven by laser illumination, the photoinduced magnetization change provides a strong evidence for the spin-charge coupling in YbFe2O4. This photomagnetic effect based on charge-order-induced multiferroicity could be used for non-thermal optical control of magnetization.


Conventional strain-based numerical prediction assumes that failure occurs when ductility is exhausted or accumulation of creep strain reaches the critical failure strain. Due to instability at the onset of rupture, the failure strain value appears to be scattered and leads to the erroneousness in prediction. In this paper, a new local constraint-based damage model incorporating the Monkman–Grant ductility, as a measure of strain during uniform creep deformation stage, was implemented into a Finite Element (FE) model to predict the creep damage and rupture of Grade 92 steel under uniaxial and multiaxial stress states. The prediction was applied on plain and notched bar specimens with various notch acuities. The uniaxial stress-dependent Monkman–Grant (MG) failure strain was adopted in the FE to simulate the influence of the constraints which were induced by the creep damage. The implication of reduced failure strain in long-term creep time on the rupture prediction is discussed. The multiaxial MG failure strain of the notched bar, which has a lower value than uniaxial failure strain due to the geometrical constraint, was estimated based on the linear inverse relationship between normalised MG failure strain and normalised triaxiality factor. It was found that the results obtained from the proposed technique were in good agreement with the experimental data within the scatter band of ± factor of 2. It was shown that MG failure strain can be used as an alternative to strain at fracture. MG strain outweighed strain at fracture because the determination of its value only required short-term testing to be performed. In most cases considered in the present investigation, the rupture-type fracture was predicted, however, there was evidence that under high constraint and low stress, stable crack propagation occurred before fracture. The location of the maximum creep damage was found to be dependent on the creep time, geometry or acuity level of the specimen. For sharp notch specimen, the failure was initiated near the notch root, however, as the notch radius increased, the initiation location moved further away towards the specimen centre.


A valuable approach for the automatic generation of effective finite element meshes is presented. The approach comprises, firstly, an initial mesh construction and, secondly, an h-version of adaptive refinement based on an error analysis. For the initial mesh construction, a robust triangulation scheme for 20 analysis and tetrahedronixation scheme for 30 analysis am used, in which the elements are generated from the outside boundaries. For the adaptive Winement process, an error indicator is used with a relaxation factor to obtain efficient solutions. The initial mesh construction schemes have been implemented for 2D and 30 analyses whereas the self-adaptive mesh improvement procedure. has only been implemented for 20 analysis. Example solutions are given to demonstrate the solution procedures.


OBJECTIVE: To investigate the post-marketing safety profile of subcutaneous interferon beta-1a (SC IFN β-1a).
BACKGROUND: SC IFN β-1a 3x/week was approved in the US in 2002 as a first-line treatment for relapsing multiple sclerosis (MS).
DESIGN/METHODS: This was an observational, retrospective cohort study using MarketScan© commercial and Medicare supplemental healthcare claims databases. Eligible subjects were 蠅18 years with 蠅1 MS diagnosis from 2006-2012 and 蠅1 prescription for SC IFN β-1a. Patients were followed from first SC IFN β-1a prescription until therapy switch or end of insurance eligibility/observation period. Analysis examined adverse events (AEs) in the SC IFN β-1a Prescribing Information (Pl). Outcomes were described at MedDRA Preferred Term level and categorized into System Organ Classes. Descriptive analyses and AE incidence rates (IRs) per 100 person-years (PYs) were calculated.
RESULTS: 8107 patients met inclusion criteria. The top 6 IRs per 100 PYs [95[percnt] confidence interval] were flu-like symptoms (FLS; IR=15.65 [14.96,16.36]), malaise (IR=15.33 [14.65,16.04]), fatigue (IR=15.02 [14.35,15.72]), abdominal pain (IR=10.18 [9.67,10.70]), chest pain (IR=8.48 [8.03,8.95]), and depression (IR=7.75 [7.32,8.20]). The lowest IRs were for injection-site reactions (IR=0.03 [0.01,0.07]), injection-site necrosis (IR=0.01 [0.00,0.03]), hypoesthesia (IR=0.00 [0.00,0.02]), and Stevens-Johnson Syndrome (IR=0.00 [0.00,0.02]).
CONCLUSIONS: Consistent with results of controlled clinical trials and the US PI, FLS, abdominal pain, and depression had among the highest incidence rates in our study. In contrast, real-world incidence of injection-site reactions was low, unlike that seen in clinical trials. This may reflect under-reporting of this AE by patients and/or providers. Overall, study results show strong convergence between the real-world safety profile of SC IFN β-1a and its US label, as reflected in the type and relative frequency of labeled events.
Study Supported by: EMD Serono, Inc., Rockland, MA, USA (a subsidiary of Merck KGaA, Darmstadt, Germany) and Pfizer Inc, New York, NY, USA. Disclosure: Dr. Smith has received personal compensation for activiteis with EMD Serono as an employee. Dr. Sabido Espin has received personal compensation for activities with Merck KGaA as an employee. Dr. Trochanov has received personal compensation for activities with EMD Serono as an employee. Dr. Samuelson has received personal compensation for activities with EMD Serono, Inc. as an employee. Dr. Guedes has received personal compensation for activities with Merck KGaA as an employee. Dr. Richy has received personal compensation for activities with Merck KGaA as an employee.


This paper mainly researches on the problem of the fire compartment of the expandable polystyrene storage that exceeds the code limit.FDS software is used to simulate the storage fire,and the simulation results show that,by controlling the amount of stored goods and the ventilation volume,the controlling effect of fire spread can be achieved.


The problems of property realization at macroand microlevels are investigated in the article. Property is considered as a multivariate phenomenon including economic, legal and political components. Special attention is given to the analysis of prerequisites, condition s, mechan ism and forms of property realization.


High-Performance Computing (HPC) systems and Datacenters are growing in size to meet the performance required by the applications. This makes the interconnection network a central element in these systems, which must provide high-communication bandwidth and low latency. One of the most important aspects in the design of interconnection networks is their topology. In that sense, the Dragonfly topology is nowadays very popular as it offers high scalability, low diameter, diversity of paths, high bisection bandwidth, etc. Routing in Dragonfly topologies is an important issue, since deadlocks must be prevented, usually by means of escape ways to break cycles. However, even with a deadlock-free routing, the performance of Dragonfly topologies degrades when the negative effects of congestion appear (e.g. the Head-of-Line-HoL-blocking). Hence, some techniques are used to reduce HoL blocking, usually based on separating traffic flows into different queues implemented by means of Virtual Channels (VCs) or similar structures. VCs are also used to implement differentiated-services provision in systems supporting applications with different levels of priority. The combination of HoL-blocking reduction and differentiated-services provision through an integrated management of VCs has been previously studied. However, this integrated management of VCs does not consider the additional use of VCs as escape ways, thus it cannot be applied to Dragonfly topologies. For that reason, in this paper, we adapt the integrated management of VCs to Dragonfly topologies, so that by using a reduced number of VCs, our proposal is able to offer differentiated-services provision, HoL-blocking reduction and deadlock freedom. Performance results, obtained through simulation experiments in medium-to-large size Dragonfly networks, show that the proposed technique outperforms other solutions.


ERP is a set of packages built information system and implemented as a facilitator for the realization of the concept of ERP in an organization. But in the ERP system implementation is not easy. User as a businessperson in addition to master the required business processes are also required to master the ERP technology. The main obstacle to overcome to implement the ERP companies is the high cost that must be paid. Therefore, in the design of ERP in this research, we use the Compiere application software which is one of open source ERP software, especially on the Purchasing Department of PT.Biru Interiorindo SCK


A CCD-based fringe detection system is under development at the Navy Prototype Optical Interferometer. The purpose of this device is threefold: It will utilize the second output beam from the beam combiner which currently is described. It will provide a versatile science instrument which may be used for special investigations while fringe tracking is carried out by the existing APD systems. Finally, it will provide a more powerful and flexible real-time fringe tracking system, capable of tracking on six simultaneous baselines. This system is designed around an intensified 512-pixel line-scan camera, which detects the output of three spectrometers at up to 79 delay points every millisecond. This results in a sustained data rate of over 40 MB/s. The data are used to close the real-time servo loop, and the raw data are archived to a 145 GB RAID. The requirements that this system must meet are discussed followed by a description of the hardware. The statistics of photon counting with this device are discussed from a theoretical standpoint.


A new transition metal-catalyzed orthogonal solid-phase protocol for the synthesis of highly substituted 2(1H)-pyrazinones was developed, on the basis of Chan-Lam arylation and Liebeskind-Srogl cross-coupling reactions. This strategy opens the way for the generation of small libraries of 2(1H)-pyrazinone analogues for biological screening.


We have begun to elucidate the role of γδ T cells in innate immunity. Purified human and bovine γδ T cells display a subtle activation, akin to priming, in response to a wide variety of pathogen associated molecular patterns (PAMPs) such as lipopolysaccharide and peptidoglycan. A primed γδ T cell displays an enhanced response to downstream secondary signals compared to resting cells, but is not overtly activated. The signature response of a primed γδ T cell include increases in Mip1α, GM-CSF, and IL-2Rα gene and protein expression, that renders them more sensitive to IL-2. Priming is distinct from overt activation by known TCR agonists in that upregulation of IFNγ and TNFα, the signature of an activated γδ T cell, are rarely detected. Priming has also been detected in vivo in γδ, but not αβ, T cells derived from the gut mucosa of Salmonella infected calves. In an effort to manipulate γδ T cells to provide an innate protective response, we have identified compounds and herbal products that mimic the priming activation of PAMPs on γδ T cells. Treatment of bovine calves with one of the plant extracts protects against Salmonella-induced enterocolitis. γδ T cell priming may be a critical step in innate immune protection and clearance, especially for pathogens that invade mucosal surfaces, where the majority of γδ T cells are found.


This report describes a technical tour of taipei, Hong Kong and Manila in April 1981. The major activity was participation in the third conference of the Road Engineering Association of Asia and Australasia (REAAA) in Taipei. A brief account of the REAAA conference and other tour activities is given, together with a listing of relevant resource material. The tour provided a valuable opportunity for interaction with professionals engaged in transport planning, and highway engineering. In future REAAA conferences, consideration might be given to different session formats to facilitate technical exchange. There would appear to be a number of areas of common interest in which communication of experiences and transfer of technology should be encouraged. These include: road investment planning techniques; urban transport management; road construction; and, road maintenance (a).


To establish the robustness of two alternative methods for predicting the future ranges and abundances for two wild‐harvested abalone species (Haliotis rubra Donovan 1808 and H. laevigata Leach 1814): single atmosphere–ocean general circulation model (GCM) or ensemble‐averaged GCM forecasts.


In The Politics of Exodus, Mark Dooley offers a lively interpretation of Kierkegaard as a precursor of the ethical and political insights of Jacques Derrida. While many connections have been forged in recent years between these two quintessentially Continentalfigures, Dooley's book argues that these affiliations run much deeper than any previous commentators have suggested. Indeed, his most controversial claim is that Kierkegaard is anything but a proponent of asocial individualism, but is one whose writings bear witness to the notion of an open quasi-communitywhich has driven much of Derrida's work over the past decade. In vigorously challenging conventional wisdom surrounding the place of Kierkegaard in contemporary thought and political theory, Dooley shows how powerfully postmodern and politically charged the latter's specifically 'religious' ideas are. As such, Kierkegaard ought to be read as someone who anticipated Derrida's claim that genuine responsibility in the political sphere depends upon a phophetic call for justice on behalf of the least among us. will appeal to anyone interested in the intersection of religion and postmodernism, as well as to those with interests in ethics and politics from a Continental perspective. It will undoubtedly change the way we read Kierkegaard in the new millennium.


Objective To analyze the effect of both limited selective posterior rhizotomy(LSPR)and limited selective soft tissue release(LSTR)on healing motor function related to spasmo-cerebral palsy in both legs.Methods Thirty-eight cases CP with LSPR and LSTR were collected in the past 3 years;21 males,17 females;aged 3.0-8.11 years old,on the average of 5.11 years old.Perioperative motor function were evaluated according to motor function scores.Results LSPR and LSTR played a role in improving motor function obviously,and had little difference in orthomorphia after SPR for 6 months.Conclusion LSPR and LSTR may improve cramp and abnormality in both legs,and enhance motor function,so the secondary operation agony can be avoided,and the family economic burden relived.


Access to information is now part of the national law as it was
adopted by the Chamber of Representatives of the National Assembly
of the Republic of Belarus on 12 December 2013. It went into effect
on 10 January 2014. The law takes the form of amendments to the
2008 law �On Information, Informatization, and the Protection of
Information�.


System captures the media content for access by sharing source user from a first media content provider, the shared source user receives a notification that is wants to share the receiving-side user the media content. The system determines an ID (identity) of the receiving-side user by sending to the receiving-side user of the computer system of the intermediate link to identify the media content, sharing the media content. System receives side user receives a notification that the selected intermediate link, transmits the ID of the ID and the receiving-side user of the media content to an intermediate server. System obtains a first universal resource locator, which is determined based on the ID of the ID and the receiving-side user of the media content (URL) from the intermediate server. The system captures the media content from the second media content provider using the first URL. .FIELD 6


A 65-year-old female MDS patient Y. M showed refractoriness to transfusions of HLA-matched platelets in 4 out of 72 occasions. Analysis of Y. M serum by a monoclonal antibody specific immobilization of platelet antigens (MAIPA) assay revealed that the serum contained anti-HPA-5b antibody directed against an epitope on platelet glycoprotein (GP) Ia/IIa. The Y. M serum was tested for its reactivity against ineffective as well as effective platelets by MAIPA assay. The serum was reactive to the platelet antigen against an epitope on GP Ia/IIa of ineffective platelets, but not against an epitope on GP IIb/IIIa, GPIb or GPIV. The serum was not reactive to any of GPs of effective platelets. Platelet typing of patient Y. M and four ineffective HLA-matched donors showed that patient Y. M was HPA-5a/a, whereas four ineffective donors were HPA-5a/b. The results indicate that HPA-5 antigen is responsible for the refractoriness to the platelet transfusion.


This work examines the conversion of various coal blends made up from individual coals, each of which had a known conversion behavior, in a series of liquefaction experiments using tetralin and 1-methylnaphthalene as solvents. First, the conversion of each individual coal was determined separately. Then, coals having high and low conversions were mixed in specific proportions and the conversion of the mixture determined and compared with the weighted average of the conversion of the individual coals. The conversion of the coal blend was found to essentially equal the weighted average conversion of the individual coals making up the blend. Thus, for the coals tested here, there was no apparent synergistic effect on the conversion of the blended coals. 1 reference, 1 figure, 5 tables.


The photoluminescent and electroluminescent characteristics of a blend polymer system consisting of a novel fluorene-carbazole copolymer (PFC) and poly(vinylcarbazole) (PVK) were investigated. Three OLED devices with the structures of indium-tin-oxide (ITO)/PVK:PFC/bathocuproine(BCP)/tris-(8-hydroxylquinoline)-aluminum (Alq 3 )/Mg∶Ag, indium-tin-oxide(ITO)/PFC/bathocuproine(BCP)/Alq 3 /Mg∶Ag and indium-tin-oxide(ITO)/PVK/ bathocuproine(BCP)/Alq 3 /Mg∶Ag respectively, were fabricated. The optoelectronic properties of the devices were measured. The results demonstrated that PVK in the blend system effectively restrained the formation of PFC excimers in solid films. Light emission of the device with blend system shifted with the variation of applied electric field, and variable color ranging from green to blue could be obtained. The luminance of blue light reached 1650cd/m 2 when the drive voltage was higher than 7V. It was inferred that an energy transfer process from PVK to PFC might have occurred in this blend system.


If you're planning to increase your school's student enrollment, improving the education quality it delivers is an excellent way to start. Having an improved education quality will not just bring more students to your school. It'll also make your school a reputable educational establishment, standing out amongst other private schools in your city or state. So, if your business plan is to improve your school's education quality, we can show you eight ways on how to do it right. That said, we invite you to spend a few minutes with us here.


Abstract Background: Size heterogeneity in red blood cells (RBCs), as indicated by elevated RBC distribution width (RDW), is increasingly considered a prognostic factor in various diseases. However, the semi-quantitative nature of the RDW value appears limited when evaluating quantitative changes in time-series RBC size distributions over a clinical course. Methods: We developed a time-series anemia monitoring program by displaying progressive differences between six size fractions in an RBC size distribution. To standardize each variation precisely, our program includes an angular transformation that is applied to all measured count ratio data. Results: By representing microcytic and/or macrocytic changes in time series independently, this method appears to improve evaluations of anisocytosis, reflecting the responsiveness of treatments and effects, such as deficiencies in iron or vitamin B12. Time-series displays of RBC size changes also appear to enable verification of latent clinical developments at earlier stages and the characterization of imbalances between RBC supply and RBC loss in anemic pathologies. Conclusions: By displaying linear relationships between RBC size categories on a time scale, our proposed monitoring method quantifies potentially applicable pathological information. This mode of representation appears to offer details about high RDW values and latent adverse outcomes related to anemic pathogenesis.


Leachates and alcoholic extracts (10%) from potential hardwood cutting material were prepared from Pinus wallichiana,Cedrus deodara, Abies pindrow, Thuja orientalis, Aesculus indica, Rhododendron arboreum, Magnolia grandifolia and Quercus incana , that grow around Shimla -the mid Himalayas. Rooting response of standard hypocotyl cutting system ( Cucumis sativus L . 8 day old cuttings that form, on average, 14 roots by ninth day of suspension in water at 25 ± 1°C continuous light) to 10, 100 and 1000 times dilutions of original extract were recorded. Concentrated leachates from wood of all species were toxic while rooting was slightly prormoted at 1000 and 100 times dilutions of original extract. Alcoholic extracts were toxic even at 100 times dilutions while 1000 times dilutions slightly promoted rooting of standard hypocotyl rooting systems. Residue of alcoholic extract applied after dissolution in water promoted rooting at 1000,100 and 10 times dilutions as well.


* Foreword by Stephen Heath Comedies * The Comedy of Errors * The Taming of the Shrew * The Two Gentlemen of Verona * Love's Labor's Lost * Romeo and Juliet * A Midsummer Night's Dream * The Merchant of Venice * The Merry Wives of Windsor * Much Ado About Nothing * As You Like It * Twelfth Night * All's Well That Ends Well * Measure for Measure Histories * Henry VI, Part One * Henry VI, Part Two * Henry VI, Part Three * Richard III * King John * Richard II * Henry IV, Part One * Henry IV, Part Two * Henry V * Henry VIII Major Tragedies * Hamlet * Othello * King Lear * Macbeth Greek and Roman Plays * Titus Andronicus * Troilus and Cressida * Julius Caesar * Antony and Cleopatra * Timon of Athens * Coriolanus Romances * Pericles * Cymbeline * The Winter's Tale * The Tempest * About the Author


The interfacial reaction behavior of Ti3SiC2/Al andTi3SiC2/Al-10si matrix composites at high temperature was studied by XRD and SEM. The results showed that the reaction between Ti3SiC2 and Al matrix is Ti3SiC2+Al→TiCx+Si+Al3Ti. Ti3SiC2 particles in the Ti3SiC2/Al composite were almost completely reacted after 700 °C/1 h treatment, whilea large amount of Ti3SiC2 particles still existed in the Ti3SiC2/Al-10Si composite under the same treatment condition. In addition, the friction coefficient and wear amount of Ti3SiC2/Al composite were 0.54 and 0.167 g, respectively, and that in Ti3SiC2/Al-10Simatrix composites were 0.29 and 0.019 g. According to the critical condition of ΔG = 0, it is calculated that when the activity of Si is greater than 0.57, the interfacial reaction between Ti3SiC2 and Al matrix is inhibited.


Several novel atropisomeric phosphine ligands have been synthesized and evaluated. The syntheses of 2-methyl-3-[2'-(diphenylphosphino)phenyl]-4(3H)quinazolinone (la) and its methyl-substituted analogs lb and ic were achieved in good yield by coupling N-acetylanthranilic acid with the corresponding phosphinoanilines 4a-c. A practical resolution of ligands la-c was accomplished using the benzenesulfonylhydrazone derivative (10) of (1S)-(+)-camphorsulfonic acid as a novel resolving agent. Several catalytic reactions including palladium-catalyzed asymmetric allylic alkylation, phosphine-catalyzed [3+2] cycloaddition of N-tosylimines with 2,3butadienoate, and asymmetric intramolecular Heck reaction were performed. The 2-methyl group of this ligand series could be activated into the olefin form in the presence of Rh(nbd)2C104. The rhodium complex was found to be able to catalyze conjugate addition of the Grignard reagent (n-BuMgBr) to enones. The synthesis of 3-[4',6'-dimethyl-2'-(diphenylphosphino)phenyl]-4(3H)quinazolinone (id) was achieved by coupling 4H-3,1-benzoxazin-4-one (71) with 4,6dimethyl-2-diphenylphosphinoaniline (4c). Ligand ld could be directly lithiated by lithium diisopropylamide (LDA). The hetero-substituted analogs le-g were synthesized in good yield by quenching the lithium anion of ligand id with electrophiles. Resolutions of ligands id and le were achieved using (-)-di-p-chloro-bis[(S)-dimethyl-(1naphthylethyl)aminato-C 2 , N]dipalladium(II) (78) and (-)-di-ji-chloro-bis[(S)-dimethyl-(1phenylethyl)aminato-C 2 , N]dipalladium(II) (7), respectively. Thesis Supervisor: Scott C. Virgil Title: Assistant Professor of Chemistry


In the XXI century, the city began to lose its appeal to people: the accumulation of elements of the artificial material world in the form of buildings and structures, increasing the number of abandoned industrial areas, the sharp deterioration of the environmental situation contributes to anti-urban trends and urban depression. Today there is an urgent problem of harmonization of human life and society in relation to the natural environment, so began to emerge architectural trends and currents, the main concept of which - unity with nature. But for the implementation of such projects aimed at stabilizing the ecological situation of the urban environment, the need for development of new territories has increased. In these conditions, the interest of depressed industrial urban enterprises is understandable, which can be fully included in the architectural environment of the city and adapted to the needs of modern society. Revitalization has become an important component of the new paradigm of renewal of the territorial space of Kyiv as a post-socialist city.
It is established that in modern cities there are almost no free territories that could be used to increase the area of public spaces, landscaping and the formation of landscape and recreational areas. Attention began to attract degraded industrial areas - areas of the city, which under the influence of social, economic, political factors have lost their purpose, are not used for their original purpose and are abandoned. Former industrial areas have great urban potential. And the secondary use of degraded industrial buildings with the subsequent eco-revitalization of the surrounding space helps to simultaneously solve the problematic issues of economy, ecology and aesthetics in the process of city life.
The article considers the concept of "ecorevitalization" as one of the elements of sustainable urban development policy aimed at preventing the development of urban areas, development of social and economic activities, ecological improvement of the environment and analyzes the ways of ecorevitation. It is established that landscaping is a search for ways to integrate wildlife with the artificial environment of human life.


The Mossbauer spectrum data of η−FexGe was determined at room temperature and liquid−nitrogen temperatrue. It was found to be the same for the composition x=1.23 and x=1.11. X−ray diffraction results are in good agreement with published data.


The extension of the city, rooted in Chilean farmer culture, makes it possible to reconstruct the edges of the territory and its urban-rural domain. Valparaiso, in the context of "city + harbor", contains an orality that contributes to the understanding of its territory and the role of women in the appropriation of the city, declared a world heritage site in 2003 for its historic quarter. The study is based on the stories of the last farmer women who worked at the Hacienda Siete Hermanas until the middle of the 20th century. The Hacienda is now the Rodelillo Hill in Valparaiso, an heir and example of urban and architectural development based on massive waves of different colonies. In this context we observe the Hacienda , one of oldest institutions in Chile, and the presence of rural women made invisible who build the city from its edges. Keywords: city + port, edges, extension of the city, women.


Tracking the information flow to mitigate the potential vulnerabilities with localization and accuracy has led to various IFT techniques with different levels of abstraction. However, each technique focusses on a particular level of granularity for information flow control which leads to limited access control or area overhead costs decreasing the precision logic of the system. This paper presents a novel approach providing both fine and coarse grain granularity by integrating Instruction level and Gate level IFT to track the data. The proposed approach translates from Instruction level to Gate level based on the user application and module instantiation.


The Alto Chicamocha Irrigation District, commonly known as "Usochicamocha" is located in the Upper Chicamocha River Basin in the Department of Boyacá, in the jurisdiction of the municipalities of Paipa, Duitama, Tibasosa, Nobsa, Sogamoso, Santa Rosa de Viterbo and Firavitoba. The district has area 9.300 hectares and benefits 6.131 users with irrigation and drainage service, annually produce 190.000 tons of food. The area of study meets agroecological conditions and optimal infrastructure for the establishment of fruit and vegetable agribusiness, with the bulb onion standing out. In Colombia, the department of Boyacá is the main producer of this vegetable with 56, 29% of the sowing area, representing 44, 63% of the production volume, with an average yield of 28, 27 t/ha. The main objective was to identify and describe the main attributes, characteristics, limitations, opportunities of the object of study in this case the producers of bulb onion (Allium Cepa L.) where the economic, technical and environmental context was analyzed and giving priority to the social. The survey was defined as an appropriate methodological tool for the collection of information, which was subsequently processed through multivariate statistical analysis. As a result of this research work it was possible to establish the structure, dynamics and heterogeneity of the different domains of recommendation in which the producers were classified, being able to define their particular (within the group) as well as the differences outside them. The product obtained becomes a significant contribution, for both farmers and the administration of the irrigation district, allowing it to make dynamic decisions in such a way as to facilitate the articulation of highly competitive markets. Key-words: Production systems, characterization, domains of recommendation, competitiveness and agribusiness.


PURPOSE
All plan verification systems for particle therapy are designed to do plan verification before treatment. However, the actual dose distributions during patient treatment are not known. This study develops an online 2D dose verification tool to check the daily dose delivery accuracy.

METHODS
A Siemens particle treatment system with a modulated scanning spot beam is used in our center. In order to do online dose verification, we made a program to reconstruct the delivered 2D dose distributions based on the daily treatment log files and depth dose distributions. In the log files we can get the focus size, position and particle number for each spot. A gamma analysis is used to compare the reconstructed dose distributions with the dose distributions from the TPS to assess the daily dose delivery accuracy. To verify the dose reconstruction algorithm, we compared the reconstructed dose distributions to dose distributions measured using PTW 729XDR ion chamber matrix for 13 real patient plans. Then we analyzed 100 treatment beams (58 carbon and 42 proton) for prostate, lung, ACC, NPC and chordoma patients.

RESULTS
For algorithm verification, the gamma passing rate was 97.95% for the 3%/3mm and 92.36% for the 2%/2mm criteria. For patient treatment analysis,the results were 97.7%±1.1% and 91.7%±2.5% for carbon and 89.9%±4.8% and 79.7%±7.7% for proton using 3%/3mm and 2%/2mm criteria, respectively. The reason for the lower passing rate for the proton beam is that the focus size deviations were larger than for the carbon beam. The average focus size deviations were -14.27% and -6.73% for proton and -5.26% and -0.93% for carbon in the x and y direction respectively.

CONCLUSION
The verification software meets our requirements to check for daily dose delivery discrepancies. Such tools can enhance the current treatment plan and delivery verification processes and improve safety of clinical treatments.


It is proved that the linear complexity of the production sequence of two LFSR sequences is less than or equal to the production of the linear complexities of the two LFSR sequences.Especially, if these two LFSR sequences are m-sequences, and if their minimal polynomials are mutually prime, then the linear complexity of the production sequence of the two LFSR sequences equals the production of the two linear complexities.


Purpose: A country's growth can better be measured in terms of financial indicators; derivatives is one of them. It is one of the evolving instruments to hedge risk and offer information about market and thereby economy. With this background, the objective of the paper is to study and compare the Indian options with European options.Research Methodology: The data has been used for Nifty and CBOE exchange for 2018-19. To analyse the determinants, options mispricing in B-S model is explained. The linear Granger causality test has been used to identify potential variable to determine implied volatility smile.Findings: The study finds difference in volatility in both the markets. It is advocated that European market is more mature than nascent Indian market.Value: Derivatives being the instruments of hedging needs to be developed in India. In this regard the paper study the relationship between implied volatility and money-ness has been analysed and compared in both the markets. The determinants affecting volatility has been identified.


The purpose of the study was to determine the process of adsorption and desorption of carbofuran at two different temperatures in two different types of Malaysian soils. The two types of soil used in this study were clay (high organic carbon content) and sandy clay (low organic carbon content). The recovery rates of carbofuran from sandy clay and clay soils were 98.7 and 76.1% respectively. The adsorption of carbofuran onto the soil corresponded well with the Freundlich isotherm. The results showed that adsorption of carbofuran decreases with increase in temperature at low initial concentration (10 μg). However, at higher initial concentrations (eg 50 μg), the influence of temperature on adsorption is not significant. The results show that the percentage adsorption of carbofuran is higher in clay than in sandy clay soils. The percentage carbofuran desorbed into the aqueous phase ranged from 57.4% to 89.8% in sandy clay and 51.7% to 75.9% in clay. The results clearly showed that carbofuran molecules were bound weakly to clay and sandy clay soils. keywords: Carbofuran, adsorption, desorption, soils, distribution coefficient


Objective: The biochemical parameters are used in scientific research in conjunction with other factors, to analyze the experimental results. Laboratory animals raised in different animal houses have variations in their values due to diet, management health status, age, the process of colecting blood and other interferences. Thus, the objective of this study was to created by conventional Bioterty Center FMUSP . Materials and Methods: We used 20 isogenic strains of mice BALB/6 and C57BL/6 and Swiss heterogeneous, 40 Wistat rats, 40 rabbits and 40 hamsters Golden New Zealand. The tests performed were: urea / BUN (Blood Urea Nitrogen), creatine, total protein, albumin and globulins, iron, phosphorus, glucose, total cholesterol and LDL (Low Density Lipoprotein), HDL (High Density Lipoprotein), VLDL (very Low Density Lipoprotein), total bilirubin and fractions (direct, indirect), chlondes, magnesium, triglucerides, ALT/AST (alanine aminotransferase, aspartate aminotransaminase), ammonium, calcium, ALP (alkaline phosphatase) and LDH (lactate denydrogenase), certain by semi-automatic spectrophotometer (Cobas Mira) and Bioclin kitas, and Labtest Biosystems. Results: Presented by the means and standard errors of the concentrations of analytes in plasma, grouped by sex. Conclusion: We determined the biochemical profiles of mice, rats, hamsters and rabbits conventional Biotery FMUSP Center, offering a valuable tool for researchers to analyze their experimental results. Certified No 251/11 CEAU HCFMUSP.


In Nigeria, the prevalence of irregular migration, human trafficking, and modern slavery reflects a socio-political deficiencies and a pure socio-economic imbalance between the rich and the poor. As a result, this study investigated the determinants and consequences of irregular migration, human trafficking, and modern slavery in Nigeria in the context of national and international perspectives. Several variables were believed to be determining factors of these events based on what is apparent in the existing literature reviewed, including poverty, low standard of living, insecurity, wealth disparity, leadership flaws, and a low level of education. This paper then concludes that, given the globalising nature of these events (irregular migration, human trafficking, and modern slavery), it would be extraordinarily impossible for any single country to adequately address the tremendous consequences emanating from these social events.


In the times of emerging technologies and rising individuals' awareness more light is shed on privacy and associated risks. This does not go unnoticed by regulators, that develop and enforce tighter requirements towards organisations. Simultaneously, outsourcing relationships develop and offshoring as well as nearshoring are still popular among cost-optimisation methods. While many security methods are discovered and developed and numerous standards and best practices exist that talk about information security management systems, there is only limited literature on how to develop and implement these controls so that they bring the expected value. The goal of this research was to present guidelines for designing and implementing information security management system controls on basis of identified risks and issues with controls existing at the time. This was to support existing financial institutions with improving their internal controls for information security when engaging in offshoring relationships. The goal was achieved through qualitative methods: case study observation followed by a questionnaire that was distributed among and answered by information security advisors and specialists with extensive experience in financial sector. Case study is a Swiss globally operating bank that outsources its processes to a number of offshore and nearshore locations. The bank has had a number of controls and processes already well established at the time of the research. This research confirms that financial institutions face various obstacles and issues at different phases of offshoring. The most commonly identified included: dispersed responsibilities, issues arising at the time of offshoring that could be identified prior to decision to outsource and finally – lack of power to enforce technical controls over vendors. The guidelines developed include but are not limited to: focus on additional areas when preparing for offshoring initative, establishing and defining responsibilities across different teams in the organisation and with the vendor and defining detailed contractual clauses. The findings from this thesis also open opportunities for further research – to investigate the relationship between these guidelines and efficiency of information security management system or to quantify impact of these guidelines in order to prioritise them. Similar research could also be conducted in other sectors and organisations to provide evidence for the research generalization.


Industry recognizes that there are very small enterprises that develop parts which contain software components. These enterprises are very important to the world‐wide economy, and the parts they develop are often integrated into products made by larger enterprises. Failure to deliver a quality product on time and within budget threatens the competitiveness of both organizations. One way to mitigate these risks is for all the suppliers in a product chain put in place recognized engineering practices. Many international standards have been developed to capture proven engineering practices. However, these standards were not written for very small development organizations, those with less than 25 employees, and are consequently difficult to apply in such settings. An ISO/IEC JTC1/SC71 Working Group has been established to address these difficulties.


Commentary on: McRobbie H, Hajek P, Peerbux S, et al. Tackling obesity in areas of high social deprivation: clinical effectiveness and cost-effectiveness of a task-based weight management group programme—a randomised controlled trial and economic evaluation. Health Technol Assess 2016;20:1–150.[OpenUrl][1][CrossRef][2][PubMed][3]

Obesity is recognised as one of the major future health challenges. Obesity is causally linked to chronic diseases such as diabetes, coronary heart disease, stroke, hypertension, osteoarthritis and certain forms of cancer. Since the 1980s, the prevalence of obesity has risen threefold in the majority of high-income countries.1 Strong …

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In this paper, the stray magnetic field of induction motor under static eccentricity, dynamic eccentricity and mixed eccentricity faults is studied, and its frequency signatures are derived, where the theoretical analysis is based on the harmonic magnetomotive force and air gap permeance of induction motor with squirrel cage rotor. Motor stray magnetic field signature analysis has the advantages of simple measurement, low cost and noninvasive. The dynamic eccentricity and mixed eccentricity faults can be accurately identified by the combining of motor current and stray magnetic field signature analysis. First, the finite element model of induction motor is developed and the stator current and stray magnetic field can be simulated. Then, eccentricity fault diagnosis experimental platform is established, and hall sensor and magnetoresistive sensor are used to measure the stator current and stray magnetic field of motor. Finally, the simulation and experimental data are analyzed and the results prove the validity of the theoretical analysis, the method of motor stray magnetic field signature analysis can effectively diagnose the eccentricity faults.


In fetuses of eight-week old female Swiss mice, teratogenic effects were produced by cyclophosphamid on different days of pregnancy. Frequently and combinations of malformation of a positive control group (30 mg/kg b.w. on the 11.5th day of pregnancy) were compared with "prophylaxis" groups. Pyrithioxin (Encephabol) significantly reduces the number of some malformations. The goal, i.e. to obtain normal fetuses without malformations, was not achieved, however. The best effect was obtained with 1/160 LD50 of Encephabol administered in four doses prior to Endoxan.


ABSTRACT: This study examines the interdependence between institutional ownership and the speed with which Standard & Poor's disseminates corporate accounting information. From the demand‐side perspective, we find that quasi‐indexers, who rely on corporate accounting information as a low‐cost monitoring system, are the key driver of the institutional demand for speedy information dissemination. In addition, dissemination speed increases substantially for stocks listed in major market indices but decreases with high arbitrage risk or transaction costs. From the consequences perspective, we find that both transient investors and quasi‐indexers gravitate to stocks with faster information dissemination, consistent with the latter using accounting information as a low‐cost performance‐monitoring mechanism, and the former being better enabled to implement their trading strategies in a richer information environment. Overall, this study provides new insights into the capital market information infrastructure by ...


This research was aimed to learn ewe�s milk production and quality of Peranakan Etawa goat milk in the first, second, third, and fourth lactation periods in UPTHMT Singosari Malang. This research total used 20 samples. The samples was taken from 4 lactati


A pentabasic acrylic copolymer has been prepared by solution polymerization.The carboxylic group in the copolymer is neutralized to form an acrylic polyol dispersion,which is used as component B to react with a low viscosity isocyanate (component A) forming the title 2K aqueous polyurethane coatings.It has shown that the amount of initiator,hydroxyl value,neutralization degree and the mixing approaches of Component A anb B will impart an important effect on the coating film properties.It is found that the coating film will provide the best all round performance when the amount of initiator is 1%,hydroxyl content 2.7%,carboxyl group is fully neutralized,and mechanical mixing approach is used.The pot life is up to 8 h ,which is longer than the similar solvent-based coatings.


To the Editor.I read with interest the contribution from You et al.1 (The American Surgeon, 64:775-777, August 1998). A century ago, a surgical alternative for the management of chronic constipation was first suggested by William Arbuthnot Lane, who championed total colectomy as the procedure of choice for this disorder.2 Recent resurrection of the procedure has generally produced excellent results.l" In an attempt to eliminate the potential for intractable postoperative diarrhea after total colectomy, You et al. propose segmental colectomy for selected patients based on the pattern of retained markers during sitzmark study. In the study by You et al.,' the patients who initially underwent total colectomy with ileorectal anastomosis had complete resolution of their constipation without problematic diarrhea. However, several of their patients who underwent segmental colectomy suffered recurrent symptoms, and all of these patients showed evidence of colonic inertia in the retained colon. Specifically, 25 per cent of the patients who underwent right hemicolectomy and 11 per cent of all patients with only a segment of colon resected required subsequent total colectomy for persistent constipation. The authors' fear of severe postoperative diarrhea did not materialize in any of these patients. As noted in prior studies, high rates of recidivism and remedial surgery in patients undergoing segmental colectomy make it a poor choice for patients with colonic inertia/" The authors' strategy of using a sitzmark study to isolate a segment of dysfunctional colon would seem to be unsound and potentially misleading. Schouten and Gordon" note that "a drawback of interpretation of such studies is that evaluation of transit of contents in any segment is dependent on the amount of markers received from the proximal bowel." All surgical candidates should undergo anorectal physiology tests to exclude those patients with anorectal outlet dysfunction as the etiology of their constipation." Unfortunately, there is always the potential for postoperative bowel dysfunction despite the best of intentions. The authors did not show any benefit (only potential problems requiring remedial surgery) to leaving a remnant of colon behind when operating for colonic inertia. To the contrary, their study provides further evidence that total colectomy is, indeed, the optimal surgical procedure for colonic inertia in carefully selected patients without anorectal outlet dysfunction. William C. Cirocco, M.D., F.A.C.S. Research Medical Center Kansas City, MO 64132


An analytical solution to the concentration of minor carriers in the base region of a PNP- type heterojunction bipolar transistor has been developed.The theoretical current gain of PNP heterojunction bipolar transistor with emitter- base- em itter structure has been calculated based on the analytical m odel.The influence of differentbase current com ponents on the current gain is discussed,including the extrinsic base surface recombination current,the interface recombination current at base con- tact,the base bulk recombination current and the mesa recombination current.


Abstract Systematic x-ray and electron diffraction studies of polymers of 1,3-butadiene prepared by different anionic catalysts have made it possible for us to identify two types of highly crystalline materials. One of us (G. N.) has already reported that our synthesis was carried out with the aid of different highly selective catalysts. The description of the preparation of these catalysts, which have made it possible for the first time to prepare these new polymers, will be separately published by one of us (G. N.) with L. Porri. Infrared analysis carried out by E. Mantica and D. Morero in our Institute has established that one type of these crystalline polymers obtained with heterogeneous catalysts represents a continuous l,4-trans arrangement of the monomer units. X-ray diffraction has shown that this material is dimorphous, having one crystalline modification that is stable at room temperature and another stable above 60° C. The x-ray melting point of a polymer having a molecular weight of the order ...


We report the development of a reagentless electrochemical impedance biosensor for glucose that employs the D-glucose/galactose receptor from E. coli for direct glucose detection. The biological platform for this sensor is an Au surface to which the protein is immobilized through formation of an Au-S bond to a genetically engineered cysteine residue at the N-terminus. The impedance signal detects the extensive ligand-induced domain motion within the protein upon glucose binding. We show the applicability of impedance spectroscopy in conjunction with periplasmic binding proteins as a general method for detecting small molecules. © 2005 The Electrochemical Society. @DOI: 10.1149/1.1943549# All rights reserved.


This experiment was conducted to study the effect of yeast concentrate on slaughter performance and carcass quality of Ross broilers.160 1-day-old Ross 308 broilers were selected and randomly assigned to 5groups with 4replicates in each group and 8broilers in each replicate.GroupⅠ was the control group which fed a basal diet.GroupsⅡtoⅤ were fed the basal diet supplemented with 2000,4000,6000 and 8000mg/kg yeast concentrate,respectively.GroupⅡ was added yeast concentrate continously at the age of 1to 42 days,groupsⅢtoⅤ were added yeast concentrate continously at the age of 1to 21 days,and 22 to 42days was not added.The feeding experiment lasted for 42 days.The results showed that at the age of 21 days,compared with the control group,groupsⅡ,Ⅲ,ⅣandⅤhad the tendency to increase the percentage of dressed weight,eviscerated yield,breast muscle yield and leg muscle yield,and decrease the percentage of abdominal fat,but the difference was not significant(P0.05).GroupsⅡ,ⅢandⅣ had significantly increased the a value of muscle and decreased the shear force of muscle(P0.05),and the b value of groupⅢ was significantly decreased(P0.05).At the age of 42 days,compared with the control group,group Ⅳ had significantly reduced the percentage of abdominal fat and improved the percentage of breast muscle yield(P0.05),groupsⅡ,ⅢandⅣhad significantly increased the a value of muscle(P0.05),groupⅡ had significantly decreased the shear force of muscle(P0.05).In conclusion,the diets supplemented with yeast concentrate could significantly improve the slaughter performance and carcass quality of Ross broilers,and it also had the lag effect.The better level of yeast concentrate was 6000mg/kg,the yeast concentrate was added at the age of 1to 21 days,and 22 to 42days was not added.


To apply more specific MS PCR method to determine the correlation between angiotensinogen gene M235T (AGTM235T) polymorphism and the onset of familial primary hypertension in Jiangsu and Anhui Provinces The TT genotype and the frequency of T allele (TT/T) in four groups ( 62 patients with both hypertension and familial background (FH), 32 normal persons who with hypertensive familial background (FNH), 26 persons in control group (N) and 10 hypertensive patients (NFH group) who have no familial background) were 0 581/0 77?0 563/0 77?0 346/0 58 and 0 4/0 55 respectively There was a excess in the T allele ( P 0 005) in FH and FNH groups compared with the groups which have no familial background In bordland of Jiangsu and Anhui, China, the onset of hypertension has a close correlation with AGTM235T polymorphism Concerning of the age, we speculated that the AGTM235T polymorphism was only associated with genetic hypertension, not all types of hypertension