One of the critical factors in the analysis of the in-vessel retention of corium during a postulated severe accident in a nuclear power plant is the interaction of corium constituents with the reactor vessel wall material. In a CANDU© reactor, after fuel channel disassembly, corium constituents would come into contact with the calandria vessel wall. Ablation of the wall due to physicochemical interaction with corium at high temperature could cause vessel failure, increasing the likelihood of radioactive release to the environment. Therefore, the interaction of the calandria vessel wall material (stainless steel 304L) with each of the main corium constituents (Zircaloy-4, Zr-2.5%Nb, Zircaloy-2, and UO2) was studied experimentally. Arrhenius equations that can be used for analysis of in-vessel corium retention were derived from experimental results. For alloys of Zr, measured rates of interaction were comparable with those reported for similar light-water reactor materials. For UO2, the rate of interaction ...


We propose a generalization of the superconducting circuit simulation of the dynamical Casimir effect where we consider relativistically moving boundary conditions following different trajectories. We study the feasibility of the setup used in the past to simulate the dynamical Casimir effect to reproduce richer relativistic trajectories differing from purely sinusoidal ones. We show how different relativistic oscillatory trajectories of the boundaries of the same period and similar shape produce a rather different spectrum of particles characteristic of their respective motions.


Abstract: Canola production in western Canada has expanded such that in many regions canola area rivals the area seeded to wheat. This change can be mainly attributed to adoption of herbicide resistant hybrid varieties and resulting higher relative profitability. Producers responded to higher seed prices by reducing seeding rates, leading to plant densities that were often lower than industry recommendations. The study objectives were to examine canola yield response to plant density and assess economically optimal density levels relative to industry recommendations and grower practices. A meta-analysis approach was applied to yield response and plant density data with herbicide resistant hybrid canola from multiple studies. Three alternative marginal yield–density functions were estimated and used to calculate economically optimal plant density. Sensitivity of results to key parameters was assessed. Resulting optimal density levels under recent average prices, seed size, and emergence were 62–73 plants·m−2, consistent with industry recommendations for western Canada. Recent field surveys report lower densities than this range, suggesting that producers are seeding at less than optimal rates; however, there is significant uncertainty associated with canola production and interaction of seeding rate with other factors. These would impact optimal plant density, although much of the uncertainty remains until well after seeding. The empirical results represent a foundation for development of more detailed models, highlight the significance of the relationship between plant density and economically optimal yield, and suggest the need to develop decision making tools to support producers in making canola planting decisions.


Abstract This article provides some corrections to the numerical results obtained in a recent paper by Duncan [2] and suggests a more efficient procedure for determining the optimum control parameters.


The aim of this thesis was to expand the existing knowledge base concerning the profile of emotional processing that is associated with major depression, particularly in terms of socially important non-verbal stimuli (e.g. emotional facial expressions). Experiment one utilised a face-word variant of the emotional Stroop task and demonstrated that depressed patients (DP) did not exhibit a selective attention bias for sad faces. Conversely, the healthy controls (HC) were shown to selectively attend to happy faces. At recognition memory testing, DP did not exhibit a memory bias for depression-relevant words, but did demonstrate a tendency to falsely recognise depression-relevant words that had not been presented at encoding. Experiment two examined the pattern of autobiographical memory (ABM) retrieval exhibited by DP and HC in response to verbal (words) and non-verbal (images & faces) affective cues. DP were slower than HC to retrieve positive ABMs, but did not differ from HC in their retrieval times for negative ABMs. Overall, DP retrieved fewer specific ABMs than did the HC. Participants retrieved more specific ABMs to image cues than to words or faces, but this pattern was only demonstrated by the HC. Reduced retrieval of specific ABMs by DP was a consequence of increased retrieval of categorical ABMs; this tendency was particularly marked when the participants were cued with faces. During experiment three, DP and HC were presented with a series of faces and were asked to identify the gender of the person featured in each photograph. Overall, gender identification times were not affected by the emotion portrayed by the faces. Furthermore at subsequent recognition memory testing, DP did not exhibit MCM bias for sad faces. During experiment four, DP and HC were presented with videotaped depictions of 'realistic' social interactions and were asked to identify the emotion portrayed by the characters and to make inferences about the thoughts, intentions and beliefs of these individuals. Overall, DP were impaired in their recognition of happiness and in understanding social interactions involving sarcasm and deception. Correct social inference was significantly related to both executive function and depression severity. Experiment five involved assessing a group of eight patients that had undergone


OBJECTIVE
To assess the prevalence and severity of pediatric emergencies in ENT in Casablanca.

MATERIAL AND METHODS
This is a retrospective study over two years from January 1st 2010 to December 31, 2011, covering 2220 pediatric othorhinolaryngology emergencies observed in the emergency department of the "20 August Casablanca" hospital.

RESULTS
Males predominate and account for 72.25% compared to 27.74% of girls. The mean age was 7.5 years ranging from 03 months to 15 years. Five pathologies top the list; head and neck wounds (28.11%), foreign bodies (21.62%), infectious emergencies (21.57%), blunt trauma (16.39%), and finally hemorrhages from natural orifices (11.22%).

CONCLUSION
This study assessed the prevalence and severity of ENT emergencies in children in Casablanca.


ABSTRACT The coronavirus mouse hepatitis virus (MHV) induces a minimal type I interferon (IFN) response in several cell types in vitro despite the fact that the type I IFN response is important in protecting the mouse from infection in vivo. When infected with MHV, mice deficient in IFN-associated receptor expression (IFNAR−/−) became moribund by 48 h postinfection. MHV also replicated to higher titers and exhibited a more broad tissue tropism in these mice, which lack a type I IFN response. Interestingly, MHV induced IFN-β in the brains and livers, two main targets of MHV replication, of infected wild-type mice. MHV infection of primary cell cultures indicates that hepatocytes are not responsible for the IFN-β production in the liver during MHV infection. Furthermore, macrophages and microglia, but not neurons or astrocytes, are responsible for IFN-β production in the brain. To determine the pathway by which MHV is recognized in macrophages, IFN-β mRNA expression was quantified following MHV infection of a panel of primary bone marrow-derived macrophages generated from mice lacking different pattern recognition receptors (PRRs). Interestingly, MDA5, a PRR thought to recognize primarily picornaviruses, was required for recognition of MHV. Thus, MHV induces type I IFN in macrophages and microglia in the brains of infected animals and is recognized by an MDA5-dependent pathway in macrophages. These findings suggest that secretion of IFN-β by macrophages and microglia plays a role in protecting the host from MHV infection of the central nervous system.


The double scroll is a strange attractor showing unpredictable transitions from one scroll to another. In the paper, an attractor is constructed that consists of n scrolls (n may be chosen). This was made possible by the development of an alternative method for studying nonlinear differential equations, called a quasilinear approach. The method is very qualitative, but it gives a global insight into the behaviour of the dynamical system and it may be used as a complement to a linearisation around equilibrium points or a Lyapunov function method.


Abstract : The mathematical modelling of the two dimensional compressible for over an open rectangular cavity is considered. The flow field is divided into three regions: (1) the two-dimensional compressible flow outside the cavity which is governed by a convective wave equation; (2) the two dimensional flow inside the cavity for which the mean flow is neglected and thus is governed by the wave equation; and (3) the shear layer spanning the cavity which is the major focus of the investigation. the work of Tam and Block is followed and a method for determining the discrete frequencies of shear layer oscillation is determined including shear layer thickness effects and assuming that the shear layer grows downstream. a line source placed at the trailing edge is used to model the trailing edge interaction process and the analysis of a shear layer excited by a reflected wave of arbitrary frequency is considered. Since the mean flow in the shear layer is nonuniform, standard stability procedures do not work. The nonparallel effects are assumed to be weak. The method of multiple scales is used to analyze the nonparallel stability of the shear layer. The stability characteristics of the shear layer are used in an equation developed by Tam and Block to predict discrete oscillation frequencies. The numerical methods for solving the equations are discussed. Originator-supplied keywords include: Open cavity flows; Nonparallel stability; and Multiple scales.


On a global basis, primary liver cancer which is almost entirely
hepatocellular carcinoma constitutes approximately 5.6% of cancers and in some
populations is the most common cancer. The largest numbers of cases are found
in Asia (76% of all hepatocellular carcinoma), followed by Africa. Annual
incidence rates for hepatocellular carcinoma are below 5 cases per 1,00,000
population in North and South America, North and Central Europe and Australia
with intermediate rates of upto 15 cases per 100,000 in countries bordering the
Mediterranean. The highest annual incidence rates are found in Korea, Taiwan,
Mozambique and Southeast China, approaching 36 per 100,000. Within each
geographic area (low or high incidence), blacks have attack rates approximately
threefold higher than Caucasians.
In India, it is estimated that there are approximately 2 – 2.5 million cases of
cancer at any given point of time, with around 7,00,000 new cases being detected
each year. Nearly half of these cases die each year3. The incidence of liver
malignancy is about 5.6 percent4 and among the top three causes of death from
cancer are included the cancer of lung (17.8% of all deaths), stomach (10.4%) and
liver (8.8%). In India, the National Cancer Registry Programme of the ICMR
provides data on incidence from five population based registries. The age
standardized cancer incidence at Mumbai in India for liver, was 4.9 per 1,00,000
in males and 2.5 per 1,00,000 in females.
1. Alpha - fetoprotein is a reliable immunocytochemical marker for
hepatocellular carcinoma.
2. The expression of alpha - fetoprotein in the cells was found to be
directly proportional to the grade of hepatocellular carcinoma.
Further studies with more number of cases can be done to prove
that this might be a useful marker to differentiate between low grade
and high grade hepatocellular carcinoma cases.
Also, alpha - fetoprotein can be included among a panel of other
known markers like HepPar 1, p – CEA and m– CEA in diagnosis of
hepatocellular carcinoma and the contribution by each of these
markers in all cases can be evaluated and diagnostic accuracy can be
enhanced.
3. Serum alpha - fetoprotein level is also related to the grade of
hepatocellular carcinoma. Levels more than 400 ng/ml are common in
high grade hepatocellular carcinoma.
4. HCV is more often associated with hepatocellular carcinoma (68%)
than HBV (11%).


This paper first introduces the theory of Stochastic Trajectory Models (STMs). STM represents the acoustic observations of a speech unit as clusters of trajectories in a parameter space. The trajectories are modeled by mixture of probability density functions of random sequence of states. Each state is associated with a multi-variate Gaussian density function, optimized at state sequence level. The effect of not using the HMM assumptions in STM is that STM can exploit information, such as time correlation within an observation sequence, which is hidden by HMM assumptions.


BY SHEILA F. G. SCHWARTZ Mediation works best when people want to plan for the future as well as to control the process and outcome of their separation or divorce. To mediate successfully, clients need to absorb information, understand choices, and make decisions.They must respect the mediation process and be willing to do the work involved. Couples mediate best when they have the intellectual and emotional


This paper reveals a torque-angle approaching principle in a hybrid rotor permanent-magnet (HRPM) motor. The key is to obtain the relationship between angles of shifted surface-inserted PMs (SPMs) as well as assisted airspace barriers and the current angles of maximum PM torque as well as maximum reluctance torque. In order to find out this relationship, the PM torque and reluctance torque are separated accurately and effectively by the proposed torque separation method. In this method, the parameters in an abc reference frame are transformed to a d--q reference frame via Park transformation, and then the model considering cross-coupling and magnetic saturation effect is used to calculate four torque components. Moreover, the shifting of SPMs has been confirmed to have both influence on the current angles of maximum PM torque and maximum reluctance torque, while the assisted airspace barriers only affect the current angle of maximum reluctance torque. Thus, the total torque can be enhanced by optimal angles of shifted SPMs and assisted airspace barriers because of higher utilization of both PM torque and reluctance torque. In order to evaluate the presented principle in the HRPM motor, a prototype is manufactured for experiments. Through theoretical analysis and experimental testing, it is verified that the proposed principle is feasible and effective.


Objective To investigate the status of Chinese medicine service of community health service station in China,and promote it's development.Methods In 2005 and 2007 respectively,10 provinces of three regions of national east,inside and west,83 community health service station were investigated.Results The number of main Chinese medicine instructions for diagnosis and treatment was in an up-trend,especially Chinese medicine suffocating apparatus and traction bed.Compared with the year 2005,the kind of medicine decreased in inside,and the kind of medicine increased in west in the year 2007.Conclusion It was necessary to establish the network of community Chinese medicine service,and educate the Chinese medicine general practitioner.


We conduct a meta-analysis to investigate how changes over time and model specifications could contribute to the differences in estimates of returns to education in China. The results show that approximately 10 percent of the variation can be explained by changes in labor market. Since the reform in 1978, returns to education have increased approximately 0.2 percentage points a year. This increasing trend has reached a stop when the global recession hit China in 2008. We find that returns to education for migrant workers are 2.3 percentage points lower than that of urban workers.


Application of the CuInSe2-based thin film for a near-infrared (NIR) photodetector (PD) has been demonstrated. The Cu(In,Al)Se2 (CIAS) was used as an absorption layer for NIR PD with comb-structured Al electrodes. X-ray diffraction spectrum and scanning electron microscope (SEM) micrographs show that the CIAS film is a single phased polycrystalline film with smooth surface and super large (2–5 μm) grains. Low temperature photoluminescence analysis indicates that the CIAS has a strong NIR excitation emission peak. The CIAS PDs are highly sensitive to the NIR spectrum with cut-off frequency near 790 nm and demonstrate four-orders of magnitude in photocurrent amplification.


Concerns about China's political and social stability figure prominently—and rightly—in Western governments' formulation of policy toward Beijing. Unlike a strong, stable, but less-than-friendly China, an unstable (and presumably weak) China presents a different set of strategic and political challenges to Western policymakers. Instability—whether economic, social, or political—makes it difficult to protect some of the important interests that have been pursued by the West during the last two decades (such as improvements in human rights, governance, and access to the Chinese market). Internally, political instability usually triggers large-scale violence and loss of government authority. In the case of China, which has a large arsenal of weapons of mass destruction, a likely fallout from such instability would be ineffective control regimes over the exports of such weapons and related technologies. Despite these profound concerns about the consequences of instability in China, however, reliable predictions about Chinese politics have been quite rare. Few analysts, for instance, foresaw the downfall of two of Deng Xiaoping's chief liberal lieutenants (Hu Yaobang and Zhao Ziyang) or the bloody Tiananmen events in June 1989. Deng's successor, Jiang Zemin, was derided as a lightweight and thought incapable of managing a smooth transition of power from the Deng era. On the eve of China's resumption of sovereignty over Hong Kong, the conventional wisdom in the West was that China would "kill the goose that lays the golden eggs." Shortly after President Clinton's visit to China in June–July 1998, there was much optimism about the prospects of political liberalization. And immediately before China and the United States signed a historic trade agreement paving the way for China's entry into the World Trade Organization (WTO), such a deal was considered unlikely because the top leadership in Beijing was judged to be hopelessly divided and paralyzed. These and other similar instances of wrong predictions about Chinese politics in general, and political instability in particular, may be attributed to an analytical approach that focuses exclusively on elite politics. Given the thick secrecy with which Chinese leaders conceal their decisionmaking process, this elite approach can yield guesswork at best. To examine the issue of political stability more comprehensively, the emphasis here is not on the characteristics of individual leaders, but on a set of environmental factors that influence decisionmaking and politics. The central premise of this analysis is that stability (or its opposite, instability) is the product of a dynamic process of change: The economic, social, and political transformation that has been going on in China in the last two decades has generated forces of both instability and stability, disintegration and cohesion. As the transformative process China's Precarious Balance: Cohesiveness and Stability in a Fast-Changing Society


The Olin Experimental Classroom at Case Western Reserve University provides a laboratory-like environment in which instructors can assess the results of trying out different teaching methods, techniques, etc. From a hasty look at three of the essential hardware components of this facility as shown in Figure 1 - keyset response units for each student, a process-control computer which scans the response units, and a display for the instructor - one could easily conclude that the Olin Experimental Classroom is simply another "student response system" or "wired classroom". In fact, the differences between the traditional student response systems and the Olin Experimental Classroom begin with the very purposes for which these facilities are intended, and the differences extend to every aspect of t h e i r respective operation.


Negative‐electron‐affinity GaP p‐n junction cold cathodes have been demonstrated. The emitted currents from these devices are of the expected order of magnitude based on the limiting material and geometric factors. Emission currents suitable for vidicon‐type tubes should be readily achievable. Theoretical analyses of the energy distributions of the emitted electrons show significant heating due to electron‐phonon scattering. To obtain lower beam temperatures would require a significant advance in material technology.


The problem of the research; is there any difference of the moral attitude between the students taught by problem based learning strategy and expository based learning strategy , is there any difference in moral att itude of the students with cognitive model (fi) and (fd), is there any interaction between the learning strategy and cognition model towards the students' moral attitude. The research used experimental one through  2 lines anava formula to test the main effect and interaction effect of problem based teaching strategy  and expository based teaching strategy with the field independence (fi) and field dependence (fd) cognitive model on the students' moral attitude at SMA Negeri 6 Palu. The research subject included was the first year students in two classes;20 students from class A and 20 students from class B. The analyses shows that; 1) there is no significant difference between the class taught by problem based learning strategy (0.54) and the one taught by expository based learning strategy (0.67). 2) There is no difference between the students' moral attitude in field independence cognitive model (fi); 60% in the experimental class and 45% in the control class. Field dependence cognitive model (fd) in the experimental class is 40% and the control class is 55%. 3) There is no interaction between problem based learning strategy and expository one as well as cognitive model on the students' moral attitude. Therefore, it can be concluded that there is no significant difference between the experimental class taught by problem based learning and the control one taught by expository based learning. There is no difference of the students' moral attitude between the students who have field independence (fi) and field dependence (fd) cognitive model. There is no interaction between the learning strategy and the cognitive model on the students' moral attitude in the Civics Education study at SMA Negeri 6 Palu.


The invention relates to a method for controlling a manufacturing process for the production of customized production objects. A succession (50) of production objects (20.1, 20.2, ...) passing through at least a partial process (100.2, 100.3) of a manufacturing process. The method ensures that in series production processing an order in the partial process (100.2, 100.3) is started at the latest after a maximum waiting time. This is accomplished by the sequence of electronically available orders (10.1, 10.2, ...) separated from the sequence (70) of production objects (20.1, 20.2, ...) is treated and a copy (60) of the order sequence (50) is generated. If the first order of the copy does not match the first production object, the job in an electronic buffer memory (400.2, 400.3) is set, and determines an appropriate order for the first production object. From this buffer memory (400.2, 400.3) of the applicator is then removed with the greatest waiting time when the previous dwell time exceeds a predetermined waiting time limit. A suitable for this job production object is brought forward and processed according to the order.


Purpose:  To investigate the presence of KIT gene mutations and immunoreactivity in 85 conjunctival melanocytic tumours and to clarify the role of KIT as a potential therapeutic target in this group of patients.


The electromagnetic calorimeters, PHOS (PHOton Spectrometer) and EMCAL (Electro-Magnetic CALorimeter) have been designed for photon detection and jet measurement in ALICE experiment at LHC. We discuss the strategy adopted for calorimetric π0 measurements via the π0 → 2γ channel in ALICE and present the two-photon invariant mass spectra obtained in p+p collisions at .


We investigate the adoption paths between pre-adoption and post-adoption in ubiquitous services (uT) based on technology acceptance model and trust theory. The results showed that there is a different mechanism in uT adoption between pre-adoption and post-adoption. And uT in Korea is now in chasm phase.


A patent owner should have access to a restitutionary disgorgement remedy. The goals served by the remedy could operate to benefit patent law aims. Depending upon the desired parameters, the remedy could serve to prevent the infringer's unjust enrichment, recapture wrongful gains to the owner who lost an opportunity to gain, deter infringement, and encourage bargaining for licenses. Congress's deletion of the infringer's profits from the Patent Act and the Supreme Court's interpretation of congressional intent as an outright elimination of the remedy do not render restitutionary principles incompatible with patent law. Even pursuant to the Court's flawed interpretation of congressional intent, an infringer's gain is permissible evidence of a patent owner's loss in appropriate cases. Also, existing law does not foreclose the option of disgorgement as a contempt sanction. To protect the limited monopoly established through a valid patent, Congress should reform the Patent Act to re-authorize a restitutionary disgorgement remedy. In keeping with disgorgement's equitable roots, disgorgement could be reserved for cases in which legal damages are inadequate. Congress also could choose to limit disgorgement's availability to instances of conscious infringement. Of course, Congress could determine that patent law's goals are distinct from other intellectual property and that restitutionary principles do not foster the intended patent law aims. At least then elimination would be clear and access to the remedy would be denied on substantive grounds.


The article deals with the issues of ensuring the economic security of the state in modern conditions. Also, the concept and main characteristics of economic security was analyzed. Safety criteria and thresholds for various macroeconomic parameters are disclosed. The foreign economic aspect of security is revealed in the context of the state customs and tariff policy. Special attention is paid to the study of the place and role of human capital in ensuring the economic security of the state.


This paper reports the results of tests conducted on tobacco processing and cigarette making machinery using the two surface method for the determination of sound power in‐situ. This test method, currently in draft form in the ASTM E33.08D committee, was originally intended for sound power measurement of heavy power plant equipment. Described in this paper is the suitability of this method to measurement of light, high‐speed machinery. Also described are the benefits of this method, namely the ability to obtain sound power levels of equipment under typical operating conditions in the environment in which it normally operates. This technique also compensates for the presence of extraneous noise sources as well as the directivity of the machine being studied.


Through-Silicon Vias [TSV] offer improved system performance by reducing interconnect length to increase device speeds, and by using stacking to reduce package form-factors and enabling heterogeneous device integration. Via Reveal' [VR] - a sequence of wafer back side process steps - is key to the successful implementation of TSV. After via formation, typically using a via-middle approach, finished CMOS wafers or interposers are temporarily bonded, face-down, to glass carriers. The TSV are then `revealed' using a combination of Si back-grind and plasma etch steps, and then passivated with dielectric. VR processes must maintain acceptably low Total Thickness Variation [TTV] to allow subsequent bonding/stacking steps. Thermal budgets must also be compatible with carrier bonding adhesives - a particular challenge for dielectric deposition. This paper will focus on 300mm plasma etch and low temperature dielectric Plasma Enhanced Chemical Vapour Deposition [PECVD] processes for VR on 300mm substrates.


Objective To examine the expression and distribution of Aquaporin 1 (AQP1) in the seminal vesicle and prostate gland of male mice during postnatal development. Methods The RT-PCR for AQP1 mRNA, Western blotting for protein, and immunohistochemistry for distribution in the seminal vesicle and prostate gland on postnatal day 15, day 35 and day 70 were carried out. Results The results of RT-PCR and Western blotting showed that the level of AQP1 mRNA and protein were significantly increased in the seminal vesicle and prostate gland on postnatal day 70 (P0.05). The positive signals of AQP1 protein were localized immunohistochemically in the smooth muscle cells of seminal vesicle and the basement membrane of glandular epithelium and the mesenchyme cells of prostate gland on postnatal day 15 and day 35, but it was hardly detected in the epithelium of seminal vesicle. Thereafter, AQP1 protein was intensively expressed in the epithelium of seminal vesicle and prostate gland on postnatal day 70.Conclusion The different expressions and distributions of AQP1 mRNA and protein in the seminal vesicle and prostate gland of mice in different ages may be related to in the development of male accessory glands.


Simulations and Modeling allows for integrating disciplines to make key decisions involving trade-offs based on resilience, cost systems engineering, cost effectiveness analysis and affordability trade space throughout the system life cycle. The methodology of this paper is to focus on measuring the performance characteristics of Model-Based System Engineering (MBSE) techniques with Building Information Modeling (BIM) for the construction industry. The paper will showcase the types of 'education and training environment' required for using MBSE as a form of adaptive engineering. The support elements of the presented systems will highlight the strategy, and implantation actions that identify, develop, and acquire Training Aids, Devices, Simulators, and Simulations (TADSS) to maximize value and effectiveness.


We present wide-field Hα images of the Galactic supernova remnant (SNR) G156.2+5.7 which reveal the presence of considerable faint Hα line emission coincident with the remnant's X-ray emission. We also present low-resolution optical spectra for a few representative emission regions. The outermost Hα emission consists largely of long and thin (unresolved), smoothly curved filaments of Balmer-dominated emission presumably associated with the remnant's forward shock front. Patches of brighter Hα emission along the western, south-central, and north-eastern regions appear to be radiative shocked interstellar medium filaments like those commonly seen in SNRs, with relatively strong [O I] λλ6300, 6364 and [S II] λλ6716, 6731 line emissions. Measured [S II] λλ6716, 6731/Hα ratios range from 0.84 to 1.57. Comparison of the observed Hα emission with the ROSAT PSPC X-ray image of G156.2+5.7 shows that the thin Balmer-dominated filaments lie along the outermost edge of the remnant's detected X-ray emission. Brighter radiative emission features are not coincident with the remnant's brightest X-ray or radio regions. Areas of sharply weaker X-ray flux seen in the ROSAT image of G156.2+5.7 appear spatially coincident with dense interstellar clouds visible on optical and IRAS 60- and 100-μm emission images, as well as maps of increased optical extinction. This suggests significant X-ray absorption in these regions due to foreground interstellar dust, especially along the western and southern limbs. The close projected proximity and alignment of the remnant's brighter, radiative filaments with several of these interstellar clouds and dust lanes hint at a possible physical interaction between the G156.2+5.7 remnant and these interstellar clouds and may indicate a smaller distance to the remnant than previously estimated.


The rapid analysis of thermal stress and deformation plays a pivotal role in the thermal control measures and optimization of the structural design of satellites. For achieving real-time thermal stress and thermal deformation analysis of satellite motherboards, this paper proposes a novel Multi-Task Attention UNet (MTA-UNet) neural network which combines the advantages of both Multi-Task Learning (MTL) and U-Net with an attention mechanism. Furthermore, a physics-informed strategy is used in the training process, where partial differential equations (PDEs) are integrated into the loss functions as residual terms. Finally, an uncertainty-based loss balancing approach is applied to weight different loss functions of multiple training tasks. Experimental results show that the proposed MTA-UNet effectively improves the prediction accuracy of multiple physics tasks compared with Single-Task Learning (STL) models. In addition, the physics-informed method brings less error in the prediction of each task, especially on small data sets.


The study proposes to examine – in the light of the challenges raised by the COVID-19 pandemic – whether and how States can suspend the performance of international law obligations in a situation of emergency. The study focuses on patterns of treaty clauses that may allow for certain exceptions (while the circumstances precluding wrongfulness are subject to a subsequent study). On one side, the research examines the GATT exceptions provided in articles XX (general exceptions) and XXI (security exceptions), and on the other side, the patterns of clauses within Bilateral Investment Treaties. Relevant case-law of WTO panels, appelate bodies and of investment arbitration tribunals is also examined.


AN INVESTIGATION OF THE LOAD-CARRYING CAPACITY OF NATURAL SUBSOILS AND BASE-SUBGRADE COMBINATIONS IS REPORTED. THE VARIABLES INVESTIGATED INCLUDED: (1) SOIL TYPE, (2) TYPE OF GRANULAR-BASE MATERIAL, (3) DEPTH OF BASE MATERIAL, AND (4) SEASONAL MOISTURE. LOADING TESTS WERE PERFORMED ON TEST SECTIONS LOCATED ON EACH OF THREE SUBGRADE SOILS (WARSAW, CROSBY, AND BROOKSTON) BOTH NATURAL AND REINFORCED WITH THREE DEPTHS (6-, 12-, AND 18-IN) OF EACH OF THREE BASE MATERIALS (PIT-RUN GRAVEL, CLAY-GRAVEL, AND CRUSHED LIMESTONE). THE INFLUENCE OF SEASONAL MOISTURE CHANGES WAS STUDIED BY LOADING THE TEST SECTIONS AT TWO SEASONAL MOISTURE PERIODS; ONCE DURING THE DRY SEASON AND AGAIN DURING THE WET SPRING SEASON. SIXTY LOADING TESTS WERE INCLUDED IN THE PRINCIPAL PART OF THE TESTING PROGRAM. ONE OF THE RESULTS OF THIS INVESTIGATION WAS THE DEVELOPMENT OF A CYCLE-LOADING PROCEDURE WITH WHICH NOT ONLY THE BEARING VALUES OF BASE-SUBGRADE COMBINATIONS CAN BE MEASURED, BUT ALSO THE ELASTIC AND PERMANENT DEFLECTION CHARACTERISTICS OF BOTH THE BASE AND SUBGRADE CAN BE DETERMINED. ALTHOUGH THE INVESTIGATION DOES NOT DEAL DIRECTLY WITH PAVEMENT DESIGN, THIS TEST METHOD HAS PERMITTED AN ACCUMULATION OF DATA PERTINENT TO AN UNDERSTANDING OF THE FACTORS CONTROLLING DESIGN. IT WAS FOUND THAT THE THREE SUBGRADE SOIL TYPES SELECTED FOR THIS INVESTIGATION HAD A WIDE RANGE IN LOAD- CARRYING CAPACITY WHICH VARIED IN ACCORDANCE WITH THEIR ENGINEERING SOIL-PROFILE CHARACTERISTICS. THE SUBGRADE SOIL WHICH HAD THE LEAST BEARING-CAPACITY ALSO HAD THE GREATEST CAPACITY FOR DEFLECTION-RECOVERY. CONVERSELY, THE SUBGRADE SOIL WHICH HAD THE GREATEST BEARING CAPACITY HAD THE LEAST CAPACITY FOR DEFLECTION-RECOVERY. THESE DIFFERENCES IN THE ABILITY OF SUBGRADE SOIL TO RECOVER DEFLECTION INDICATE THE NEED FOR ADDITIONAL RESEARCH TO CORRELATE THIS CHARACTERISTICS WITH DESIGN AND CONSTRUCTION PROCEDURE. WITH REGARD TO THE LOAD-CARRYING CAPACITY OF BASE-SUBGRADE COMBINATIONS, IT WAS FOUND THAT FOR LARGE VALUES OF PLATE DIAMETER-BASE DEPTH RATIO THE BEARING CAPACITY DEPENDS PRIMARILY UPON THE CHARACTERISTICS OF THE SUBGRADE SOIL; FOR DECREASING VALUES OF PLATE DIAMETER-BASE DEPTH RATIO THE BEARING CAPACITY OF THE COMBINATION BECOMES INCREASINGLY DEPENDENT UPON THE STABILITY OF THE BASE MATERIAL. THE RESULTS INDICATE THAT THE DENSITY AND THE GRADING CHARACTERISTICS OF THE BASE MATERIALS ARE THE MAJOR FACTORS WHICH INFLUENCE BASE STABILITY. /AUTHOR/


The adaptive function of sex remains, today, one of the major unsolved problems in biology. Fundamental to achieving a resolution of this problem is gaining an understanding of the function of meiosis. The sexual cycle in eukaryotes has two key stages, meiosis and syngamy. In meiosis, typically a diploid cell gives rise to haploid cells. In syngamy (fertilization), typically two haploid gametes from different individuals fuse to generate a new diploid individual. A unique feature of meiosis, compared to mitosis, is recombination between non-sister homologous chromosomes. Usually these homologous chromosomes are derived from different individuals. In mitosis, recombination can occur, but it is ordinarily between sister homologs, the two products of a round of chromosome replication. Birdsell & Wills (2003) have reviewed the various hypotheses for the origin and maintenance of sex and meiotic recombination, including the hypothesis that sex is an adaptation for the repair of DNA damage and the masking of deleterious recessive alleles. Recently, we presented evidence that among microbial pathogens, sexual processes promote repair of DNA damage, especially when challenged by the oxidative defenses of their biologic hosts (Michod et al., 2008). Here, we present evidence that meiosis is primarily an evolutionary adaptation for DNA repair. Since our previous review of this topic (Bernstein et al., 1988), there has been a considerable increase in relevant information at the molecular level on the DNA repair functions of meiotic recombination, and this new information is emphasized in the present chapter.


This article is devoted to the search for primary ideas concerning the theoretical origins of the concept of microfascism and determining its connection with the topic of subjectivation and desubjectivation. The author suggests looking at these problems from the perspective of the French philosopher J. Deleuze and the German sociologist T. Adorno. The author pays special attention to the comparison of the ideas of both thinkers, analyzing not only the concepts mentioned by them to clarify the problematic field of microfascism, but also those social phenomena that have become the object of criticism of both authors. The article examines how their views have historically developed and transformed. The main conclusions of the study are following : 1) in both authors views, the problems of microfascism are connected with their criticism of modern capitalist society, which has adopted the fundamental features of historical fascism; 2) desubjectivation in the interpretation of J. Deleuze is defined as the dominance of the inhumane "logic of capital" over all possible ways of asserting the desire of the subject, and T. Adorno is defined as the displacement by culture of all opportunities to show non-stereotypical and unconventional ways of self-expression of the individual; 3) both authors cannot give an exact recipe for overcoming the prevailing social problems and the subsequent disintegration of human subjectivity and insist on the need to change the ways of understanding and the perception of culture.


This paper analyzed physicians' and patients' needs at various levels systematically through the hierarchy of needs theory and analyzed the consistency and conflict on both physicians' and patients' needs. It also put forward the feasible approach to improve physician-patient relationship as well as meet needs of both sides.


The present database pooling was performed to investigate the clinical phenotype in pediatric factor V G1691A (FV) and factor II G20210A (FII) carriers. 230 pediatric patients with deep venous thrombosis (DVT: n=143) or arterial ischaemic stroke (AIS: n=94) carrying either the FV (n=178) or the FII variant (n=52) not suffering from additional thrombophilic risk factors were consecutively enrolled from 2 US centers and one German database. Antithrombotic therapy was performed according to standard protocols either with LMWH/vitamin K-antagonists (DVT) or LMWH/ASS (AIS) for 6 months (range: 3–indefinitive). Patients were followed for a median of 5.4 years (range: 1–23). FV children with first disease onset were significantly younger compared with patients in the FII group (p=0.02), and showed more abdominal vein thrombosis than children with the FII variant (p=0.02). Following withdrawal of antithrombotic therapy a first recurrent event was diagnosed in 12 of 178 children with the FV mutation (6.7%), whereas pediatric patients with the FII mutation showed recurrent thrombosis in 6 of 52 patients (11.5%). Median (range) relapse time was 6.5 years (0.1–15.2) in FV carriers compared with 15 years (13–16) in the FII group (p=0.06). Interestingly, recurrent thrombotic events were recorded significantly more often in children with DVT compared with AIS (p In conclusion, the clinical phenotypes of FVC and FII are different with respect to first thrombotic onset, and thrombotic locations, and recurrent thrombosis in both phenotypes occurred more often in DVT compared with AIS.


The paper discusses the situation with textbooks and educational literature published by representatives of the Turkic-Tatar emigre communities in the Far East during the 1930s–1940s. They were meant for the needs of Tatar primary schools (4–6 years) that functioned during the second quarter of the 20th century in most cities of Manchuria and Japan (Tokyo, Nagoya, Mukden, Harbin, Hailar, etc.) and were dominated by the humanitarian and Tatar cultural component. At the same time, due to the small number of communities, as well as the lack of technical base and material resources, separate textbooks on the Tatar language, Tatar history, and the basics of arithmetic operations created during the pre-revolutionary period were published and popular among the population. Thus, the Turkic-speaking emigre communities, for a number of reasons, could not create a new original content and published only what was in the pre-revolutionary educational and pedagogical legacy. Interestingly, these factors helped to preserve the continuity of generations for the new Turkic-Tatar emigre population and contributed to their inclusion in the general Tatar cultural context. It was also facilitated by the fact that the Far Eastern Tatar emigre communities used the Arabic script as the basis of the Tatar written tradition for the longest period of time (at least until the late 1940s – early 1950s).


Photonic crystal fibers are pure silica optical fibers with an array of air holes that run along the length of the fiber. The development of these fibers, in both solid and hollow core varieties, has been significant over the past 15 years and they are increasingly finding new applications in a variety of sensing areas where they can offer opportunities distinct from conventional optical fibers.


This research work was made with the main objective of the feasibility study for the creation of a housing project for the construction of villas off with wooden house in the parish and marketing Vilcabamba in Loja Canton.
I use various methods such as scientific, analytical, deductive and inductive techniques such as direct observation, interview and survey them that allowed me to collect relevant information for this project.
And can perform market research in which I apply basically the survey to 381 households A and B socioeconomic Loja Canton real estate projects and 5- fifths of existing rest in Vilcabamba parish, and demonstrate that there is an actual demand for 1642; on the supply side I have the amount of 5 holiday properties for the first year, which is not enough because there is an unmet demand for 1594/5 off.
Within the technical study I were able to calculate the installed capacity will be 8/5 rest and 6 farms capability used for the first year. It was also possible to determine the macro and micro localization of the company, as I note that there is the availability of raw materials, ease of access for consumers , ease of transportation , utilities , infrastructure, among others in the market , so the location determined more pro will be in Canton Loja, Vilcabamba parish , Mollepamba - Yasanga sector.
In the organizational study determined the constitution of the company, which will have the same business name MERINO REAL CIA. LTDA. and will be of limited liability , the staff working on the administrative side will be a General Manager , a Secretary , a legal adviser , a Seller a Accountant , an Architect two Guards -six Laborers , they be identified in the structural organization chart and functional , and responsibilities are defined in the manual functions.
The financial study to delimit the total investment for this project is $ 193,088.04 to be financed with a 22% contribution from shareholders and 78% with a credit on the National Finance Corporation, in addition to the first year costs will be of $ 323,077.04, the revenue reached $ 420,000.16, reaching about a net profit of $ 58,699.06.
The economic evaluation was determined an NPV of $ 62,679.55, was also obtained an IRR of 20.75 % well above the 9.24% interest bank loan, plus investment recovered in 2 years, 11 months and 19 days, was determined likewise a Short - Benefit Ratio of 1.30 and finally it was decided that the project would support up to a 11.35% increase in costs and a decline to 8.73 % of revenues.
Finally using each method and technique could perform the above studies favorable results in each of them allowing I to conclude that it is feasible to create a building project for the construction of villas off with wooden house in the parish Vilcabamba and Loja marketing in Canton.


de Mercados de Energia, S.G.C.C.C.C., S.A. Av. Casal Ribeiro, 14 – 8o // 1000-092 Lisboa – Portugal T (+351) 210 006 000 F (+351) 210 006 001 www.omiclear.eu NIPC 506 956 318 Capital Social 3.000.000 Euros EBA Discussion Paper on Draft Regulatory Technical Standards on the capital requirements for CCPs under the draft Regulation on OTC derivatives, CCPs and Trade Repositories (EBA/DP/2012/1) OMIClear contribution [02.April.2012]


The fixed-lag smoothing problem with a partial lag is the problem in which the presence of the smoothing lag is allowed only in a part of estimation channels. This paper studies the effect of a partial smoothing lag on the achievable H∞performance in the continuous-time case. In particular, the limit of the achievable performance is established and the saturation of the achievable performance for a finite smoothing lag is analyzed.


[PROBLEMS] provides that the adhesion is possible to form a desired fine resist pattern, the composition for forming a resist lower layer film. [MEANS FOR SOLVING PROBLEMS] following formula (1) or (2) a polymer having a structure represented by the terminal of the polymer chain, cross-linking agent, to promote the cross-linking reaction compound and the lithographic resist underlayer film forming composition containing the organic solvent for. (Wherein, R


The article proposes a procedure for evaluation of the application's efficiency (AE) of parachute systems (PS) for the air dropping (AD). Based on the analogy with the index of combat effectiveness of armament and military equipment, the AE of PS can be evaluated by using the typical mission performance probability of AD - personnel or cargo positioning to site, while maintaining their combat capability to accomplish a mission of the parachute assault force.
In this formulation, the process of accomplishing the typical mission of AD consists of the following stages: delivery of cargo to the airborne objective area, the exit of the aircraft to the computed air release point, the actual air dropping. Further analysis showed that the most influential factors affecting successful accomplishment of the typical mission of AD by the stages are: the reliability of the aircraft, the ability to overcome the enemy air defense without consequences for the accomplishment of AD, the property retention of PS while in flight considering flying conditions of the aircraft to the area of the AD, problem solving of determining of the computed air release point under the actual conditions, the accuracy of the aircraft's exit to the computed air release point, the reliability of the PS, the covertness of the AD, the accuracy of cargo's landing to the size-defined site, speed of the cargo's landing. For each of the factors, the calculating formulas were defined in the article in the form of the probability of a positive influence on the successful accomplishment of the mission of the AD. The product of all these probabilities is evaluation of the AE of PS.
For example, the calculations of the AE of PS DPS and Status-CH types in equal conditions of AD and Status-CH by using various tactical techniques of AD were made. The results of the calculations are completely consistent with the logical considerations and practice of the PS application, which testifies to the adequacy of the proposed procedure and the feasibility of its application.


Improvements to tractors. A firewall 24 separates the workstation 12 located at the rear of a tractor 10, its motor 34, located at the front. Air inlet louver 48, a transverse radiator 36, a fan 64, the motor 34 and an air outlet grille 46 are arranged downstream of each other, back and forth; the center of gravity A of the motor 34 being located at the preliminary to the front steering axle 32 and a fuel tank 40 being arranged to channel the cooling air arriving via the apertures 48. Application: soundproofing of agricultural tractors and better weight distribution .


Abstract A method has been devised for reproducibly separating from soils minimally altered, clay‐size soil organic‐mineral particles (SO‐MPs) by water dispersion and density centrifugation. Active surfaces of SO‐MPs so obtained should represent more closely those actually interfacing with root systems and microbes than the chemically cleaned clay or humic materials conventionally obtained in laboratory prepartions. The method reduces heterogeneity within given size fractions of SO‐MPs, which is desirable for studying relationships between composition and properties of minimally altered soil "fines".


Research progress of Fagopyrum esculentum Moench in recent years of the world was summerized.That was concentrated mainly on chemical composition and protein activity.It could provide references for the research and utilization of Fagopyrum esculentum Moench.


Film induced tourism or film tourism is a result of destination image formation and development through film industry with collaboration of other destination image stakeholders (policy makers, private and public investors, scholars and etc.). This postmodern tourism phenomenon links film driven emotions to the filming locations and at the same time is responsible for positive or negative destination image formation. In Lithuanian academic discourses this theory, as well as the impact of films towards local tourism, was not yet recognized. Therefore this article, according to the collected film tourism theoretical material, analyses Lithuanian potential for film induced tourism and how can it be turned into a destination promotion strategy. The conclusions show that there are real opportunities for Lithuania to use film industry as a tool of destination image formation, however it needs further analysis, a clear strategic plan, strong collaboration with Baltic region and the use of two recommendation models, which were presented in this paper. This research can be used for dynamic analysis as well as strategic planning in any specific institution related to filmmaking, tourism and regional image formation. KEYWORDS: film tourisms, destination image, film-based touristic image. JEL CODES: L82, L83; M31 DOI: http://dx.doi.org/10.15181/rfds.v19i2.1283


Molten oxide electrolysis (MOE) is an extreme form of molten salt electrolysis, a technology that has been used to produce tonnage metals for over 100 years - aluminum, magnesium, lithium, sodium and the rare earth metals specifically. The use of carbon-free anodes is the distinguishing factor in MOE compared to other molten salt electrolysis techniques. MOE is totally carbon-free and produces no CO or CO2 - only O2 gas at the anode. This project is directed at assessing the technical feasibility of MOE at the bench scale while determining optimum values of MOE operating parameters. An inert anode will be identified and its ability to sustain oxygen evalution will be demonstrated.


There is a big world out there, and volunteers can make a significant impact in helping you reach out to others and grow your PTA membership. In fact, word-of-mouth marketing tied for the top spot as the most effective method of new member recruitment in Marketing General's 2010 Membership Marketing Benchmarking Report. So getting volunteers' help is not just a good idea, but an essential part of membership development.


The DECspec project was inaugurated to explore the application of formal methods in a production environment. The goal was to take an existing method and provide support tools suitable for use in the environment discussed, and similar environment elsewhere. The Larch formal specification method, with C as the target programming language, was selected. The experiences of the first year of that project are described, together with the extensions which have been made to the Larch method, and the tools which were developed.<<ETX>>


The normal-mode frequencies of a finite simple-cubic Rosenstock-Newell bicrystal with a coherent planar interface are evaluated and analysed as functions of the relative thickness of the component subcrystals using three different general boundary conditions. The calculation was performed using the matrix reduction formalism developed for finite-layered structures. The result obtained includes details of earlier work based on a different method as a special case. It also provides some additional insights into the characteristics of vibrational modes in a finite bicrystal, such as the existence condition for a 'localised-localised' (LL) interface mode.


Background and objectives: Although inflammatory changes are found throughout the airways of patients with chronic bronchitis (CB), the mechanisms of the pathogenesis of CB are still unclear. The aim of this study was to investigate airways inflammation in patients with and without an exacerbation of CB. Granulocyte macrophage-colony stimulating factor (GM-CSF) levels in serum and bronchoalveolar lavage (BAL) fluid were assayed. Materials and methods: 40 CB patients and 10 never smoking, age and sex matched controls were studied. 20 of the CB patients were studied under baseline conditions (B), and 20 during an exacerbation (E) of CB. Bronchoscopy and bronchoalveolar lavage (BAL) with cytological analysis were performed for 7 males from CB(E) group, and 6 males from CB(B) group. The levels of GM-CSF were determined in sera and in BAL supernatants by a solid phase enzyme immunoassay. Results: There was high significant elevation of serum GM-CSF in both CB (E) and CB(B) groups in comparison with the control group (P<0.0001 & P=0.002 respectively). Both serum and BAL GM-CSF levels were elevated in CB(E) group in comparison with CB(B) group (P=0.0001 & P=0.009 respectively). Also there was significant elevation of BAL neutrophils, eosinophils and lymphocytes in CB(E) in comparison with CB(B) (P<0.05, P<0.01 and P<0.01 respectively). There was only significant positive correlation between BAL GM-CSF and BAL neutrophils count in CB(E) group, while no significant results were detected in CB(B) group. Conclusion: During exacerbations of CB there were changes in the cell populations in BAL of patients consistent with a recruitment of polymorphonuclear leucocytes, eosinophils and lymphocytes in the airway lumen. These recruited different inflammatory cells could work together toward the production of airway abnormalities and lung destruction. The locally elevated levels of BAL GM-CSF might be a cause and /or a result suggesting a role for this cytokine in the inflammatory processes of chronic bronchitis. The elevated levels of serum GM-CSF in chronic bronchitis may be due to the interference of other cytokines, microenvironmental factors in bone marrow and/or other factors. Introduction Chronic bronchitis (CB) is a clinical syndrome defined by cough and chronic sputum production occurring on most days of the month for at least 3 months a year during the two years prior to the study. Sputum is defined as expectorated lower respiratory tract secretions and is composed of fluid and cellular components, including macrophages, bronchial epithelial cells and inflammatory cells (Seatta et al, 1997). The major risk factor for the development of CB is cigarette smoking, but the precise pathogenetic mechanism of chronic sputum production is still unknown. CB is associated with intermittent exacerbations (chronic bronchitis with acute exacerbations [CB(E)]) that present with worsening of the chronic symptoms of productive cough and dyspnea. These exacerbations cause considerable morbidity and in patients with concomitant airway obstruction are major causes of mortality. CB(E) can have one or more of several different etiologies including viral


In this study, a three-port DC–DC converter is proposed based on quadratic boost converter. The proposed converter contains paths to enable the flow of power from input source to load and battery. Furthermore, it makes a path available to energise the load by the battery. The proposed converter has a bidirectional path using two additional switches and two diodes. Power flows from the input source and the battery to the load in a single-stage resulting in higher efficiency. The proposed converter has three switches and two duty cycles defined. By adjusting the duty cycles, maximum input power and output voltage can be regulated based on the input source power and the battery condition. To control the proposed converter, three operation modes are defined. In order to design the control system, the proposed converter is analysed and the small-signal models are obtained. Using a decoupling network for the integrated small-signal models, separated closed-loop controllers are designed. Finally, a prototype for the proposed converter is prepared to validate feasibility and effectiveness of the proposed converter and the control method by experimental results.


Human Ro 60 gene structure, organization and sequence alterations in cutaneous lupus erythematosus T.P.M I LLARD, * G.H. S.ASHTON, * G.R.V.HUGHES,{ J. L .M.HAWK, * J.M.MCGREGOR{ AND J.A.MCGRATH* *St John's Institute of Dermatology and {Lupus Research Unit, StThomas' Hospital, London, {Centre for Cutaneous Research, St Bartholomew's and the Royal London School of Medicine and Dentistry, London, U.K.


Taurine (TAU), a naturally occurring sulfur‐containing amino acid, is found at high concentrations in plasma and mammalian tissues and regulates osmolarity, ion channel activity, and glucose homeostasis. Several reports have shown that physiological plasma TAU levels seem to be important for adequate beta (β)‐cell function and insulin action, since low concentrations of TAU in the plasma have been reported in the pre‐diabetic and diabetic states.


The construction method of presplit blasting of high side slope is introduced .It can be used as a reference to the similar construction of slope excavation.


PVL positive Staphylococcus aureus has been associated with invasive infections, with high mortality in cases of necrotizing pneumonitis. I hope to share my experience of clinical cases in the UK and discuss the significance of PVL, including the role of PVL testing in our local setting. Selected Publications for Reference 1. A Holmes, M Ganner, S McGuane, T Pitt, B Cookson, A Kearns. Staphylococcus aureus Isolates Carrying Panton-Valentine Leucocidin Genes in England and Wales: Frequency, Characterization, and Association with Clinical Disease. Journal of Clinical Microbiology 2005; 43: 2384-2390. 2. FP O'Hara et al. A Geographic Variant of the Staphylococcus aureus Panton-Valentine Leukocidin Toxin and the Origin of CommunityAssociated Methicillin-Resistant S. aureus USA300. Journal of Infectious Diseases 2008; 197 : 187-194. 3. L Wijaya, LY Hsu. Community-associated Methicillin-resistant Staphylococcus aureus Skin and Soft Tissue Infections. Proceedings of Singapore Healthcare 2010; 19(3) : 212 -219. 4. A Spaan, T Henry et al. The Staphylococcal Toxin Panton-Valentine Leukocidin Targets Human C5a Receptors. Cell Host & Microbe 2013; 13 : 584-594. 5. Dumitrescu O, et al. Beta-lactams interfering with PBP1 induce PantonValentine leukocidin expression by triggering sar A and rot global regulators of Staphylcoccus aureus. Antimicrobial Agents Chemotherapy 2011; 55 : 3261-3271. Department of Microbiology & Immunology Programme Seminar Series ... August 2015


This paper deals with the proposal of a practical method for reducing turning motion resistance of the multi-powered wheel vehicle. In the previous paper the same kind of idea as this practical method for improving the turnability of the tracked vehicle was introduced. From that discussion it was found that the proposed method can be effectively applied for actual use of tracked vehicle and it reduced the turning motion reisitance drastically compared with the normal turning motion. Through the experiments, almost the same amount of reduction of turning motion resistance as the tracked vehicle could be observed. This proposed idea of reducing the resistance can be practically applied to commercial off-road vehicle for improving the turnability and the manoeuverability for obstacle negotiation. ~KeywordJ turnability, terrain vehicle, steerabillity, obstacle negotiation, multi-powered wheel vehicle


In a preceding paper (1956) the writers reported that pigmentation occurs in varyinig degree among strains of most species of the proposed but as yet undescribed new genus, Dekkeromyces. Hybrids may yield more pigment than either parent, thereby permitting easy selection of hybrids from a population consisting of both hybrids and parent species. This method of isolating hybrids requires one or both of the parents to produce a small or moderate amount of pigment, but neither parent should be strongly chromogenic. Another procedure has been devised for separating hybrids from their parents. The parent strains may be selected without regard to the amount of pigment they produce, but they must differ from each other in the assimilation of two carbon sources. Because this study has resulted in the first ascosporogenous yeasts known to ferment both maltose and lactose, and because the hybrids reported here may be of particular interest to geneticists, the results of this study will be presented in greater detail than was done in the previous study.


In this and a following paper we generalize the method of approach by the convergent polynomial expansion (CPE) for both elastic diffractive and inelastic nondiffractive hadron-hadron collision processes at high energies. The presence of spurious cuts in some of the conformal mappings used earlier is pointed out. A conformal mapping of the unsymmetrically cut costheta plane, which does not develop any spurious cut or require any knowledge of zeros, is combined with that of the s plane to construct a variable chi(s,t) which has the potentialities to reproduce some known scaling variables and Regge behavior and to provide information about asymptotic behavior of slope parameters of the type approx. (lns)/sup n/, with n=0,1,2. Away from the diffraction peak the variable becomes b(s)(lnt)/sup 2/. Because of the absence of spurious cuts in the mapped plane, the variable has the potentialities to provide information on the possible existence of entire functions for the differential-cross-section ratio f(s,t) at asymptotic energies. However, the rate of convergence and the nature of the polynomials in the proposed CPE are not uniquely fixed at finite energies. Only at asymptotic energies the polynomials are uniquely the Laguerre polynomials and the CPE goes over to the optimized polynomial expansion.more » The possible existence of a scaling function for the differential-cross-section ratio at asymptotic energies as a series in Laguerre polynomials in the variable chi is pointed out. The first term in the expansion in the CPE gives a good description of the energy dependence of the forward slopes for different processes without needing any effective shape of spectral function. From the asymptotic behaviors of slope parameters obtained from data analysis we find that qualitatively the forward slopes for ..pi../sup + -/p and K/sup + -/p scattering grow at the some rate, like approx. lns, as s ..-->.. infinity.« less


Described the application of archives management in fisheries production,quality control of fishery products and fisheries economic operation,pointed out the current situation and problems of fisheries management,put forward recommendations of fisheries archives management,so as to provide references.


In some practical situations, most systems would degrade with time and suffer failure finally by both causes of additive and independent damages. From such a viewpoint, this paper considers replacement models for combining with two kinds of damages: The unit is replaced at a planned time or when the total additive damage exceeds a failure level, whichever occurs first, and undergoes minimal repair when independent damage occurs. First, a standard cumulative damage model where the unit suffers some damage due to shocks and the total damage is additive is considered. Second, the total damage is measured at periodic times and increases approximately with time linearly. Using the techniques of cumulative processes in reliability theory, expected cost rates are obtained and optimal policies which minimize them are derived analytically. Finally, optimal policies are computed and compared numerically, and useful discussions for such results are done.


This article is devoted to the main periods of the life and creative activities of D.G.Shatalov. It shows his merits in strengthening the system of training skilled musicians of the region to achieve great mastery of folk instrumental performance. In this article are analyzed the most characteristic principles of Shatalov and his own methods of upbringing musicians-performers.


With regard to the existing problems of the teaching "digital signal processing",it is important to emphasize both theory and application.In the three respects as basic,advancing and interesting study,multimode teaching is adopted.The practical research proves that multimode teaching can cultivate the ability of theory connecting with practice and the ability of analyzing and solving problem independently.


Based on the theories of organizational climate and employee silence, this paper studies the relationship between the organization climate and all variables of social silence, large number of studies have shown that pro-social silence is influenced by organizational ethical climate. We find that caring climate, law and code climate, rule climate and independence climate are positively associated with pro-social silence; instrumental climate is negatively associated with pro-social silence; at the same time, a high degree of obedience to authority will strengthen the rules climate and pro-social silence positive correlation.


The communication mechanism is the base of research of mobile agent system. Based on the analysis of some kiuds of communication mode, we present a communication framework of mobile agent system based on MADP protocol. This article introduces the MADP protocol. Secondly, we analyze this communication framework, and expound the inner relationship of each parts. We discuss some implementation technologies about it.


Many computing problems of today require supercomputer performance, but do not justify the costs needed to run such applications on supercomputers. In order to fill this need, networks of high-end workstations are often linked-together to act as a single virtual parallel supercomputer. This project attempts to develop software that will allow less expensive `desktop` computers to emulate a parallel supercomputer. To demonstrate the viability of the software, it is being integrated with POV, a retracing package that is both computationally expensive and easily modified for parallel systems. The software was developed using the Metrowerks Codewarrier Version 6.0 compiler on a Power Macintosh 7500 computer. The software is designed to run on a cluster of power macs running system 7.1 or greater on an ethernet network. Currently, because of limitations of both the operating system and the Metrowerks compiler, the software is forced to make use of slower, high level communication interfaces. Both the operating system and the compiler software are under revision however, and these revisions will increase the performance of the system as a whole.


In 1824, Lindley described Chlorophytum orchidastrum, using cultivated material introduced from Sierra Leone by George Don. Later, Dalzell (i850) described plants from 'Malwan' and from the Syhadree hills of Maharastra, India, as C. nimmonii and C. glaucum respectively. However, he subsequently stated (in Dalzell & Gibson, I861), 'we have a strong suspicion that it [C. nimmonii] will turn out to be identical with C. orchidastrum of Sierra Leone'. Wight (1853) described plants from Coimbatore, India, as Phalangium ? oligospermum, illustrated as t. 2038, but had doubts about his generic assignment. Baker (1876) agreed with Dalzell's (i86i) observation and treated C. nimmonii Dalz., Phalangium ? oligospermum Wight and C. orchidastrum Lindl. as conspecific, a course subsequently followed by Hooker (1892), Cooke (1905), Ridley (1924), Fischer (I928) and Gagnepain (I934), so that the African binomial became established for a wide-spread taxon in India, Thailand, Indo-China and Malaya. Baker later (1898), however, revised his earlier treatment, restricting the name C. orchidastrum Lindl. to West Tropical African plants, and Ridley (1925) described the Malayan plants from Perak and Perlis as C. malayense and distinct from the African and other Asiatic species. Although Larsen (1961) treated C. orchidastrum as a collective species, he stated (1963) that the Thailand plants with 2n = 56 differed from the Liberian plants with 2n = 28, illustrated by Baldwin & Speese (195I, Fig. i i, left). Sheriff & Gopala Rao (i97I) and Boraiah & Fathima (197i) reported independently that plants from Ghana were diploid with 2n = 14We are therefore confronted with the problem of diagnosis and nomenclature for the African and Asian plants. After an examination of the material in the Herbarium at Kew I have concluded that they represent four distinct species:


Cattle represent an important source of animal-derived food-products; nonetheless, our knowledge about the expression of drug metabolizing enzymes (DMEs) in present and other food-producing animals still remains superficial, despite the obvious toxicological consequences. Breed represents an internal factor which modulates DMEs expression and catalytic activity. In the present work, the effect of breed upon relevant phase I and II DMEs was investigated at the pre-transcriptional and post-translational levels in male Charolais (CH), Piedmontese (PM) and Blonde d'Aquitaine (BA) cattle. As specific substrates for cattle have not yet been identified, the breed effect upon specific cytochrome P450s (CYPs), glucuronyl or glutathione transferase (UGT and GST, respectively) DMEs, in terms of catalytic activity, was determined by using human marker substrates. Among CYPs, benzphetamine


We have successfully grown a novel type of epitaxial metallic multilayers consisting of ultrathin ferromagnetic tetragonal τMnAl and nonmagnetic (CsCl‐type) NiAl on (001) GaAs substrates using molecular beam epitaxy. Reflection high energy electron diffraction and cross‐sectional transmission electron microscopy (TEM) show that monocrystalline MnAl/NiAl multilayers are formed with the expected epitaxial orientations and that the c axis of the tetragonal structure of the ultrathin MnAl film is aligned perpendicular to the substrate. Composition modulation is clearly evidenced by TEM even when the thickness of each MnAl and NiAl layer is as thin as 3 monolayers. Perpendicular magnetization of the MnAl/NiAl multilayers is shown by both magnetization and magnetotransport measurements at room temperature, exhibiting remarkably square hysteresis loops, high values (Mr≳300 emu/cm3) of remanent magnetization, and relatively low values of coercive field (0.2


Baking of proteins at 215 o C in admixture with sodium L-ascorbate severely aggravated the antinutritional effects in mice but L-ascorbic acid ameliorated their toxic activity. In the present work, thermal analysis of these materials was performed by differential scanning calorimetry (DSC) in oxygen in order to clarify their different reactivities. DSC curves of gluten and casein were similar but differed from that of soybean protein isolate. Thermochemical aspects of crust baking and high temperature food browning are discuted


Temporary passive traction sutures holding the eye into elevation enhanced the success of operations to remove the short superior oblique tendon sheath which was restraining elevation in adduction (Brown's syndrome). The technique, results, and complications of surgery are discussed.


Objectives To study the effect of an urban perinatal health programme in Rotterdam, the Netherlands, on perinatal outcomes. Design A retrospective cohort study with difference-in-differences analysis using individual-level perinatal outcome data from the Dutch Perinatal Registry 2003–2014 linked to Central Bureau of Statistics data of migration background and individual disposable household income. Intervention The programme consisted of perinatal health promotion, risk selection and risk-guided pregnancy care, and a new primary care child birth centre. The programme was implemented during 2009–2012. Primary outcome measures We compared trends in perinatal mortality, preterm delivery and small-for-gestational-age births between targeted urban neighbourhoods in Rotterdam (n=61 415) and all other urban neighbourhoods in the Netherlands (n=881 202). The effect of the programme was modelled as a change in trend of each perinatal outcome in the treatment group post intervention compared with the control population from January 2010 onwards. All analyses were adjusted for maternal age, parity, ethnicity and individual-level low socioeconomic status (SES). We also conducted a stratified analysis by SES. Results During 2003–2014, downward trends in perinatal mortality (adjusted OR (aOR) 0.9439 per year, 95% CI 0.9362 to 0.9517), preterm birth (aOR 0.9970 per year, 95% CI 0.9944 to 0.9997) and small-for-gestational-age births (aOR 0.9809 per year, 95% CI 0.9787 to 0.9831) in the entire study population were observed. No demonstrable changes in these trends were found in the intervention group after the programme had started. The stratified analyses by SES showed no changes in trends post intervention in both strata either. Conclusions The programme had no demonstrable effects on perinatal outcomes. The intervention may not have reached a sufficient proportion of the population or has provided too little contrast to the widespread attention for inequalities in pregnancy outcomes occurring simultaneously in the Netherlands.


The main features of the modern market business environment are constant changes. This leads to an uneven use of material, informational, human and financial resources. Functional separation of processes leads to the need for additional coordination of all stages of the production process and increased costs in production management. Therefore, at present, the need arises in the production management system for the search and application of effective management methods. One of the priority management initiatives is the reengineering of business processes. Reengineering provides for the implementation of the most effective business management methods for the enterprise. The purpose of reengineering is to improve the basic indicators of the economic activity of the enterprise. Reengineering is especially relevant for enterprises that operate in today's unstable market conditions. The advantages of reengineering are a quick reaction and transformation of the enterprise's business processes taking into account changes in the internal and external market environment. Reengineering provides for the preservation of the company's values and at the same time the improvement of business processes, namely: optimization of technology and labor resources; revision of measuring system and organizational structure; increasing responsibility for the results of labor and the flexibility of the production system. Achieving positive results becomes possible provided that a reengineering strategy is formed and implemented. The reengineering strategy is formed on the basis of rules and procedures for optimizing and improving business processes. The formed reengineering strategy allows you to reduce risks in the implementation of management decisions, as it maximally focuses on the factors of the market environment. When implementing reengineering, four stages are distinguished: development of a reengineering strategy; detailing of the reengineering project; implementation of detailed solutions; evaluation of the results. The implementation of a reengineering strategy, as a rule, is accompanied by the emergence of certain organizational and managerial problems. The main problems can be related to the preparation of initial information, the choice of the type of information, adequate consideration of the time factor, optimization of planned indicators, taking into account emerging non-standard situations, overcoming internal resistance. The implementation of the reengineering strategy allows us to achieve continuous improvement of the working business processes of the enterprise, due to the rejection of inefficient, superfluous, obsolete processes and increase its economic efficiency.


Lmx1b is a homeobox transcription factor vital for proper limb dorsalization, as well as development of structures in the kidney, brain and eye. Within the developing limb bud, expression of Lmx1b is limited to the dorsal mesoderm.


A resin composition for a coating material comprising a curing agent (B) and an epoxy-modified polyurethane resin (A) which is the product of reacting a carboxyl group-containing polyurethanepolyol containing repeated units derived from reacting an isocyanate compound (a) and a polyol (b) with a hydroxycarboxylic acid (c) with an epoxy compound (d) in such a proportion that the epoxy group falls in a range of 0.1 to 1 equivalent per equivalent of the carboxyl group.


The kernel cutting and the real-time reform scheme of Linux,parallel interface,the principles of the stepper motor and the compiling module steps in Linux were introduced in this paper.The date port of parallel interface was controlled through the programming.The high and low alternating cycle was sent to the specified pin to realize the drive of the stepper motor.Then the CNC can be controlled.Methods and theory base were offered for further research and development of Real-time NC system.


BACKGROUND
 Many studies on food safety cognition and practice intervention among university students exist, but only few conduct needs assessment surveys. In recent years, We-media has been applied in the field of health education and promotion, but its application in food safety intervention is limited at home and abroad.

 OBJECTIVE
 This study aimed to explore the current situation of We-media use and assess the needs for food safety information through We-media among junior students of a normal and a medical university.

 METHODS
 A cross-sectional survey was conducted among junior students of a normal and a medical university in Chongqing, China in 2016. A total of 1,250 normal university students and 1,434 medical students participated in the questionnaire survey.

 RESULTS
 Findings reveal that 71.4% and 64.8% of normal university and medical students were willing to accept food safety educational information by We-media, respectively. In addition, 47.6% and 48.8% of normal university and medical students were willing to accept food safety information through WeChat official accounts, respectively. Among normal university students, 83.8%, 63.9%, 59.6%, and 13.0% wanted to acquire food safety knowledge by picture, text, video, and voice, respectively. Of the medical students, 84.7%, 67.7%, 62.3%, and 11.9% wanted to acquire food safety knowledge by picture, text, video, and voice, respectively. Gender, school category, and whether food safety information is given attention were the influencing factors of participants' willingness to accept such information through We-media (p < 0.05).

 CONCLUSIONS
 This study indicated that We-media could be an appropriate intervention approach for the junior students of a normal and a medical university to accept food safety intervention. WeChat was also revealed as the best platform. Pictures, text messages, and videos were observed the most popular means for students to acquire food safety knowledge.


Serotonin (5-hydroxytryptamine, 5HT) is a biogenic amine involved in modulation of emotions and behaviors, as well as in the regulation of cardiovascular, respiratory, gastrointestinal and immunological functions. In order to investigate serotonin role in various physiological processes and pathological states, we developed an animal model termed Wistar Zagreb-5HT rat, which has constitutively altered both peripheral and central 5HT homeostasis. Model consists of two sublines developed by selective breeding of Wistar rats and characterized by increased (high- 5HT subline) or decreased (low-5HT subline) values of platelet 5HT transporter activity, platelet 5HT level, as well as plasma free 5HT. 5HT regulation of immune functions may be mediated either indirectly through central neuroendocrine pathways or directly through several distinct receptors expressed on immune cells. Our initial work on Wistar Zagreb-5HT rats demonstrated that animals from low-5HT subline have increased natural cytotoxic activity, as measured by natural killer (NK) activity and antibody-dependent cellular cytotoxicity (ADCC), in comparison to animals from high-5HT subline. On the other hand, immunization of the rats with sheep red blood cells (SRBC) resulted in ~ 50 % lower antibody titer in sera of low-5HT animals as compared to high-5HT animals. These results point to differences in adaptive immune response between sublines of rats with constitutively altered 5HT homeostasis and indicate opposite effects of 5HT on distinct immune reactions. Taking into account that symptomatic asthmatic patients have increased 5HT plasma levels that directly correlate to impaired pulmonary function, we suggest that Wistar Zagreb-5HT rat can serve as a useful model for investigation of pathophysiological role of 5HT in asthma and other allergic diseases.


The Cul/NN-dimethylglycine hydrochloride catalyzed reactions of amines with gamma-bromo-substituted gamma,delta-unsaturated ketones in the presence of K3PO4, and NH4OAc led to the formation of the corresponding polysubstituted pyrroles in good to excellent yields.


As for the distributed capacitor not taken into account in the conventional fault location algorithm, a single phase-ground fault location algorithm based on neural network with the distributed capacitor taken into account is proposed in this paper. The proposed algorithm uses neural network to correct the fault location distance dynamically. The MATLAB simulation results and dynamic modal experiments results suggest that the proposed algorithm have a high precision and could overcome the influence of the distributed capacitor and the ground resistance.


This review summarizes the biological and ecological factors of hexaploid wheat (Triticum aestivum L.) that contribute to trait movement including the ability to volunteer, germination and establishment characteristics, breeding system, pollen movement, and hybridization potential. Although wheat has a short-lived seedbank with a wide range of temperature and moisture requirements for germination and no evidence of secondary dormancy, volunteer wheat populations are increasing in relative abundance and some level of seed persistence in the soil has been observed. Hexaploid wheat is predominantly self-pollinating with cleistogamous flowers and pollen viability under optimal conditions of only 0.5 h, yet observations indicate that pollen-mediated gene flow can and will occur at distances up to 3 km and is highly dependent on prevailing wind patterns. Hybridization with wild relatives such as A. cylindrica Host., Secale cereale L., and Triticum turgidum L. is a serious concern in regions where these species ...


As far as current scenario is concerned Internet, computer, electronic gadgets and networking are essential. These are mostly prone to security threads like viruses, Trojan horses and other malware attacks. To check authentication, provide efficient techniques for encryption and decryption, and develop security mechanism intrusion detection system is used. IDS gather information and analyze the unusual activities to find loop holes in security from network traffic in a system. Primary task to identify the elements those are responsible to violate the system security. In this study, impact of Ant Colony Optimization for suitable decision in network based IDS are discussed.


The intrinsic viscosity of cyclic polystyrenes (C-PS) and linear polystyrenes (L-PS) with molecular weight (MW) ranging from 16K to 370K was measured in THF using size exclusion chromatography coupled with a triple detection system. The C-PS samples were prepared by a ring-closure reaction of telechelic linear precursor synthesized by anionic polymerization. As-synthesized C-PS samples after the ring-closure reaction contain various byproducts, and they were fractionated by liquid chromatography at the critical condition to obtain highly pure C-PS. While the intrinsic viscosity of L-PS agrees well with the literature data, C-PS shows significantly lower value than the literature values. The Mark–Houwink exponent of C-PS is 0.67, somewhat lower than 0.70 for L-PS in the good solvent over the MW range examined. Therefore, the ratio of the intrinsic viscosity of C-PS to L-PS (g′ = [η]C/[η]L) in THF is not MW independent but decreases as MW increases (0.63 ≥ [η]C/[η]L ≥ 0.57). The trend of intrinsic viscosity...


An experiment was conducted in the summer season of 2019 and 2020 at the National Agronomy Research Centre to find out the response of various establishment methods and dates on the performance of rice. The experiment was carried out in 2 Factorial Randomized Complete Block (RCB) design with 3 replications in an area of 12 m2 and planting geometry of 25 cm between rows and 20 cm between plants.  The establishment methods were Sprouted Direct Seeded Rice (SDSR) broadcasting, puddled transplanting, and unpuddled transplanting at three dates viz. 10th June, 26th June, and 10th July. Twenty four hours water-soaked seeds were allowed to sprouting for 48 hours and broadcasted in a puddled plot. 22 days old seedlings were transplanted in a puddled and unpuddled plots.  Recommended doses of fertilizer @ 100:30:30 N:P2O5:K2O kg  ha-1 was used in the experiment. SDSR produced the highest yield of 4.2 Mt ha-1 compared to puddled transplanting method with 3.4 Mt ha-1. The highest grain yield was recorded on 10th June (5.9 Mt ha-1) followed by 26th June (4.0 Mt ha-1). Sprouted direct seeded rice permitted to mature early and produced the higher grain yield.


The Sorption behavior of I" on calcined Mg/AI layered double hydroxide (LDH) was investigated. The batch sorption experiments were carried out in an inert atmosphere and at a constant temperature of 25 °C. Sorption is based on stepwise ionexchange equilibria involving the LDH hydroxide. The determined equilibrium constants of K̂ and K2 are 7.4±1.0 and 0.2±0.4, respectively. The dominant reaction is the first ionexchange equilibrium, which is the replacement of one 0H~ ion of the LDH hydroxide by an T ion to form MgeAl2(OH)"(I)(s). The K, value for T sorption is 5 times higher than that for MOj (M = To, Re) sorption. An iodide ion is more selective for sorption on the calcined LDH. The sorption behavior of I" in the presence of TcOj was investigated. The batch sorption experiments were conducted by using I" and ReO^ as a TcOj Surrogate. The sorbed concentrations of 1" and ReOz in simultaneous sorption are similar to those in Single ion sorption. The I" and ReOj show an independent sorption behavior on calcined LDH when these anions are mixed. It means that Mg6Al2(0H),7(Re04) exists with Mg6Al2(OH),7(I) in the LDH unit.


The BEPCII project is for upgrading the Beijing Electron Positron Collider to reach a higher luminosity. BEPCII is designed as micro-P plus multi-bunches with double rings and has adopted cryogenic superconducting technology. The BEPCII control system is a distributed system based on EPICS. In the past few years, we went through the design stage, R&D stage, development stage and the system will be installated. The BEPCII machine commissioning with beam will start in October 2006. This paper describes the BEPCII control system and the progress of its development.


In this paper, a new finite volume method on moving unstructured-grid system is presented and developed for compressible flows. The present moving-grid finite-volume method includes new algorithm for eliminating and/or merging cells according to a change of geometry, which makes it possible to calculate flow around bodies which are united into a single body or separated into another multiple bodies. A control volume for discretization is considered in the space-time unified space, which assures both physical and geometrical conservation laws even if the grid system is moved as well as deformed with eliminating or merging cells. The present method is described for two dimensional space in detail and validated using simple test problems. Applications to a gun tunnel problem and a two bodies docking and separation in a supersonic flow show a promising feature of the method. key Words : Computational Fluid Dynamics, Compressible Flow, Unsteady Flow, Unstructured Mesh, Finite Volume Method


The COVID-19 pandemic has generated a great demand for effective vaccines to control SARS-CoV-2 that causes the disease. In particular, mRNA vaccines against that virus have taken the lead as the fastest vaccine candidates. However, RNA molecules tend to degrade spontaneously, leading to a key challenge to design super stable mRNA molecules for a refrigerator-stable vaccine. In this paper, to accelerate the research of mRNA vaccines, we develop a machine learning method to predict likely degradation rates at each base of RNA molecules in the Eterna dataset, which has been devised for COVID-19 mRNA vaccines. By employing graph convolutional networks with a multi-head attention mechanism, we successfully achieve the goal to predict the degradation of mRNA molecules based on their structure information. After applying K-Fold cross validation and pseudo-label technique, our model reaches a mean columnwise root mean squared error 0.3512 on the Private Test set at Kaggle platform. Such result ranks top 4% on the leaderboard, and can get a silver medal prize in the Kaggle competition.


40 to 50 days older piges died in succession in a hogpen of Manasi county. It was diagnosed as edema disease of pig,by epizootiology survey,examination of pathology,isolation and identification of bacteria. We made an oil vaccine by the pathogenic escherich. The disease was controlled by inoculation vaccine.


In this paper the author studies the sealing-performances of the screw-type viscous pump using it as a sealing axpparatus, and examines theoretically the effects of each dimension of the screw groove for the pump lift. It is shown that in order to obtain maximum lift, the dimensions of the pump must satisfy certain conditions as follows : a) the axial length, radius and angular velocity of the rotor and the kinematic viscosity of the sealing fluid are proportional to the lift respectively. b) the lift is inversely proportional with square of the clearance gap. c) the width of the groove to be equal to the width of the thread. d) the ratio of width to depth of the groove to be 5∼20 : 1. e) the ratio of the gap to the depth to be about 0.2 : 1. f) the helical angle to be about 10∼11 degree.


Tens of billions of dollars are spent each year worldwide on airport infrastructure to promote safe, efficient, and environmentally friendly operations. Airport layouts, allocations of gates to carriers, and the manner of deploying ground equipment or personnel can dramatically affect passenger delays, fuel consumption, and air and noise pollution. Airport planners require reliable information about how different spheres of airport activity interact and how system performance would change with alterations to physical infrastructure or operating practices. The authors developed a discrete-event simulation model that can be used for strategic decisions regarding the provision and effective utilization of infrastructure needed for airside operations at major airports. The authors calibrated the model with detailed activity data for an entire year, verified its ability to represent essential spheres of activity, and illustrated its application to study system performance under several operating scenarios.


Compression is the reduction in size of data in order to save space or transmission time. For data transmission, compression can be performed on just the data content or on the entire transmission unit (including header data) depending on a number of factors. In this study, we considered the application of an audio compression method by using text coding where audio compression represented via convert audio file to text file for reducing the time to data transfer by communication channel. Approach: we proposed two coding methods are applied to optimizing the solution by using CFG. Results: we test our application by using 4-bit coding algorithm the results of this method show not satisfy then we proposed a new approach to compress audio files, by converting an audio file in to a text file and then compressing the new text file by using the common compression techniques is 6-bit coding algorithm its used to convert a digitized Audio file into a text file it is show that a good compression ratio between 15-35 %.


A 41-year-old woman was involved in a landslide caused by heavy rainfall in July 2018 in Hiroshima City, Hiroshima, Japan. She was trapped in her car and was drifted away by the landslide. She was soaked in earth and sand up to her face, but she managed to escape by herself from her car. She then


Evidence, in the form of bottom simulating reflectors (BSRs), for gas hydrates is observed on a multichannel seismic reflection profile in the continental slope area of the southern Jalisco Subduction Zone, off Manzanillo, Mexico. The reflectors are found at 0.4 sec (two-way travel time) below the seafloor reflector and extend for about 7 km along the profile. This result along with previous results in the northern part of the Jalisco Subduction Zone suggests that gas hydrates may exist in the continental slope region of the entire Jalisco Subduction Zone, however, more seismic reflection data needs to be collected to verify this assertion.