To the Editor: Pyruvate kinase (PK) deficiency is a rare disease caused by mutations in the PKLR gene encoding the red blood cell (RBC) PK enzyme, leading to defective glycolysis and chronic hemolytic anemia. The estimated prevalence of clinically diagnosed PK deficiency ranges from 3.2 to 8.5 per million in Western populations; however, the disease may be underdiagnosed and the true global prevalence may be higher. Patients with PK deficiency can develop multiple complications including gallstones, pulmonary hypertension, and iron overload regardless of transfusion status. Similar to other hemolytic anemias, PK deficiency can also lead to reduced bone mineral density (BMD), which may result in premature osteopenia, osteoporosis, and bone fractures. A PK deficiency natural history registry (N = 254) found bone fractures and bone deformities in 17% and 9% of patients, respectively. The mechanisms leading to reduced BMD in patients with PK deficiency may be similar to those of other hemolytic disorders that are associated with BMD loss, including: erythroid hyperplasia widening the marrow spaces; iron overload and iron chelation, potentially resulting in dysregulated osteoclast and osteoblast function and increased bone resorption; endocrine disruptions, which may interfere with normal bone growth and bone mineral deposition; and genetic factors. Low BMD (Z-score < 1.0) is common in other hemolytic disorders such as thalassemia and sickle cell disease, with an estimated prevalence of 77% and 80%, respectively. In thalassemia, increasing age has also shown to be a strong predictor of low BMD. The prevalence of low BMD in patients with PK deficiency has not been systematically assessed, and the mechanisms leading to BMD loss are not well defined. Therefore, the overall patient burden of BMD-related complications is poorly understood. To better characterize BMD abnormalities in PK deficiency, this study evaluated the prevalence of low BMD as assessed by dualenergy X-ray absorptiometry (DXA) scans and patient medical history review in pooled pretreatment baseline data from three global clinical trials of mitapivat in patients (≥18 years) with PK deficiency (Figure S1). DRIVE-PK (N = 52; NCT02476916) was a phase 2, randomized, open-label study of patients who were not regularly transfused. ACTIVATE (N = 80; NCT03548220) was a phase 3, randomized, placebo-controlled study of patients who were not regularly transfused. ACTIVATE-T (N = 27; NCT03559699) was a phase 3, single-arm, open-label study of patients who were regularly transfused. Baseline DXA scans were done at screening for ACTIVATE and ACTIVATE-T, and at screening or up to 3 months before the start of the study for DRIVE-PK. Scans were done locally for all three studies, and were interpreted centrally for ACTIVATE and ACTIVATE-T and locally for DRIVE-PK. Tand Z-scores, derived from DXA scans at three locations (total femur [combined neck and total hip], femoral neck, and spine), were used to classify patients into BMD categories according to standard definitions. A T-score compares a patient's BMD with that of an average healthy 30-year-old and is used to diagnose osteopenia and osteoporosis in men aged ≥50 years and women of nonchildbearing potential (here, a score of ≥ 1.0 at all locations was classified as normal BMD, < 1.0 to > 2.5 at one or more locations as low BMD or osteopenia, and ≤ 2.5 at one or more locations as very low BMD or osteoporosis). A Z-score compares a patient's BMD with that of a person of the same age and sex and is used to diagnose low BMD in men aged <50 years and women of childbearing potential (here, a score of ≤ 2.0 indicates low BMD). The findings reported in this study show the proportion of patients with low BMD based on worst DXA scan Tor Z-score, depending on age and childbearing status, at one or more of three locations. In addition, the patient's medical history was collected at screening and reviewed for prior diagnosis of osteopenia or osteoporosis, concomitant use of anti-osteoporotic medications, history of bone fracture, and number of RBC units transfused and transfusion episodes in the previous year. All findings reported here are summarized as descriptive statistics and stratified based on age and childbearing status. A total of 159 patients enrolled in DRIVE-PK, ACTIVATE, and ACTIVATE-T; 157 patients had baseline DXA scans available and were included in this analysis (Tables S1 and S2): 19.7% of patients (N = 31) were men ≥50 years or women of nonchildbearing potential and 80.3% of patients (N = 126) were men <50 years or women of childbearing potential. Among the 31 men ≥50 years and women of nonchildbearing potential, 27 patients (87.1%) had a baseline worst T-score of < 1.0 in one or more of three locations, indicating low BMD, including all (6 of 6) patients who were regularly transfused and 84.0% (21 of 25) of patients who were not regularly transfused. Six patients (19.4%) had a baseline worst T-score of ≤ 2.5 in one or more of three locations, consistent with osteoporosis, and 21 patients (67.7%) had a baseline worst T-score of < 1.0 to > 2.5 in one or more of three locations, consistent with osteopenia (Figure 1A). Data for BMD by Received: 9 September 2022 Revised: 30 November 2022 Accepted: 6 December 2022


Deeply pipelined, superscalar processors require accurate branch prediction to achieve high performance. Two-level branch predictors have been shown to achieve high prediction accuracy. It has also been shown that branch interference is a major contributor to the number of branches mispredicted by two-level predictors.This paper presents a new method to reduce the interference problem called agree prediction, which reduces the chance that two branches aliasing the same PHT entry will interfere negatively. We evaluate the performance of this scheme using full traces (both user and supervisor) of the SPECint95 benchmarks. The result is a reduction in the misprediction rate of gcc ranging from 8.62% with a 64K-entry PHT up to 33.3% with a 1K-entry PHT.


Many frameworks are available today to help organizing and performing Enterprise Interoperability projects efficiently. There are also many metrics available to measure the interoperability degree between systems. However, there is a real lack in methodologies to control Enterprise Interoperability improvement projects execution. The aim of this paper is to introduce a new approach to control interoperability improvement projects execution by using control theory, project planning theory and RatIop.


In Tamil literature there are many ideas which stress the importance of Environment and Environmental awareness of people. "Vinjani" a famous short story writer has written a story titled 'Munnai itta Thee'. The story is about a Dye industry. This industry would spoil river water and underground water used by the people of villagers. It would pollute the land and water with chemicals. Though some people may get jobs in the industry, the land would become barren. In future, the industry could spoil the environment. So, people of the area start a movement to stop this under the leadership of Sathyamorthy, a retired pollution officer and social activist. This article analyses the environmental pollution which is the central theme of this story and a major problem of this world.


This study examined the efficacy of a psychoeducational approach in treating unipolar depression. The vehicle of treatment was a course in "Coping with Depression." An explicit educational experience, the course addressed several specific target behaviors (social skills, thinking, pleasant activities, and relaxation) as well as more general components hypothesized to be critical to successful cognitive-behavioral therapy for depression. Sixty-three individuals who met Research Diagnostic Criteria (RDC) for unipolar depression were randomly assigned to one of four conditions: class, individual tutoring, minimal contact, or delayed treatment control. Participants in the immediate treatment conditions were assessed pre- and posttreatment and at 1- and 6-month follow-up sessions; the delayed treatment group was assessed prior to and following an 8-week waiting period. Results indicated clinical improvement by all of the active treatment conditions compared to the delayed treatment condition. Differences between active treatment conditions were small, and some differences between high and low responders to treatment were found. Results are discussed in terms of their implications for future clinical use of this approach. Stimulated by recent theoretical developments, there has been an impressive proliferation of interventions and approaches for the psychological treatment of unipolar depression. Treatments derived from cognitive positions have been aimed at depressive thought processes (e.g., Beck, Rush, Shaw, & Emery, 1979; Fuchs & Rehm, 1977), whereas those derived from behavioral positions have been aimed at the improvement of social skills (Hersen, Bellack, & Himmelhoch, 1980; Sanchez, Lewinsohn, & Larson, 1980; Zeiss, 1977), at increasing pleasant activities and time management relaxation skills (Lewinsohn, 1977), and at more general problemsolving skills (McLean & Hakstian, 1979). In


The fluctuation model with Gaussian-type of barrier heights distribution that was recently applied successfully to explain the dark current–voltage characteristics of Au/GaAs barrier structure with microrelief interface, in this paper is extended to photoelectric characteristics. In addition to the change of the Richardson constant and the apparent temperature coefficient of barrier height we predict the decrease of the open-circuit voltage of photodetectors or solar cells. The theoretical predictions have been verified experimentally on the Au/GaAs Schottky barriers with dendrite-like or quasigrating interface prepared by wet anisotropic etching.


And here's the final cherry on top. With this job, there's no need to do any of that dreary market research or strategy development stuff, because every newspaper, every radio station, every TV channel and every other half decent (and not so decent) current affairs medium will all be falling over themselves to give you the complete low-down on what your prospects think about you and your competitors, and which brand they intend to support on the Big Day. Plus, of course, no end of unsolicited advice on what you need to do to change that projected outcome.


Abstract: This article examines the moralistic language and arguments used in relation to genetics. The focus is on three practices: (1) the claims that there is a duty to know about one's own genetic makeup, (2) assertions that genetic information should be used to inform reproductive decisions, and (3) the proposition that there are moral reasons to participate in biobank research. With these three, the author contends that there are equally good, if not better, arguments to challenge them from a Millian perspective. Furthermore, especially in the current political climate, there is a need to respect people's privacy concerns.


The authors present an approach to classify a brand's buyers into groups with varying degrees of loyalty along a continuum from "hard-core loyal" to "hard-core switcher." A classification scheme is developed based on the joint use of stated consideration set and brand switching data. The resulting loyalty taxonomy yields five mutually exclusive segments: Hard-Core Loyal (HCL), Soft Loyal (SL), Soft Switcher (SS), Hard Switcher (HS), and Hard-Core Switcher (HCS). The five classifications from the proposed taxonomy generalize the "loyal" versus "potential switcher" segments derived from previous analyses of brand switching data. In an empirical application to the automobile industry, the authors show that the current switching databased models substantially overstate the number of the hard-core loyals (buyers who repurchase with probability one) versus the taxonomy's classification, which is based on both consideration and purchase data. These overestimates can mask the relative health or sickness of brands within the product category. The authors also illustrate how the proposed taxonomy can aid managers in understanding markets and addressing and targeting buyers with varying degrees of loyalty.


Background  While disparities in the health status for persons ageing with intellectual and developmental disabilities have been well documented, interventions that address individual risks in physical, emotional, social and environmental health among this population are lacking. This pilot study evaluated the feasibility of two inhome interventions designed to reduce health risks and improve health outcomes among persons ageing with intellectual and developmental disabilities.

Method  Interventions and assessment tools were developed. Adults with intellectual and developmental disabilities, aged 32 and over (n = 201) living in non-institutional settings were recruited and assigned to either an advance practice nurse (APN) intervention of inhome multidimensional assessment, targeted recommendations and follow-up visits (n = 101) or an inhome health risk appraisal (HRA) with printed feedback only (n = 100).

Results  The development and pilot testing of the interventions, assessment tools and methods demonstrated feasibility in the population from mild to moderate intellectual and developmental disabilities. In addition, high levels of health risks were identified (mean = 5.0; range 0–16) in the sample suggesting the need for effective interventions. Both pilot groups showed significant reduction in health risks between baseline and follow-up. Further rigorous randomized field trials are required to test the effectiveness of each intervention.

Conclusions  Community-based preventive interventions are feasible for randomized trials in this population.


With the development of China's fashion resale market, sustainable consumption patterns have gradually become popular in China. Although the prospects of China's fashion resale market are recognized, more and more consumers are also actively participating in the circular consumption model. Consumers have multiple identities in participating in resale, and can be sellers or buyers. However, the sales intention of Chinese consumers to participate in resale as sellers is still unclear. We need to understand what value Chinese consumers are looking for in resale as sellers. The focus of this exploratory study is to understand the intention of Chinese consumers to sell unwanted fashion items as sellers to determine the key attributes that affect customer value and participation. This study applies consumer value theory to explore consumers' sales intentions and potential themes. This empirical study collected a sample of 1217 seller resale reviews from social media platforms, using LDA text mining, textual point of view extraction, and co-occurrence plotting for data analysis. Nine potential themes were drawn. The results show that lifestyle change is the primary reason why most consumers participate in resale. The perception of their self-concept prompts Chinese consumers to participate in resale. This article provides theoretical and practical significance.


The paper presents the quantitative evaluation of the importance of the system's elements with series structure, taking into account two cases of specifi cation of reliability parameters: constant; time de pendent. The exemplification of importance of elements is done u sing charts and tables, considering a system with s eries connection of 3 elements.


Heart Failure (HF) accounts for 5.7 million deaths annually, which often are the result of acute or chronic ischemic injury due to myocardial infarction (MI). MI is associated with cardiomyocyte death succeeded by scar tissue formation. This scar tissue serves as a mechanical barrier and prevents normal electrical conductivity through the ventricles, thus contributing to the development of arrhythmias. Various stem cell therapies for cardiac repair are directed towards replacing injured myocardium with healthy cardiomyocytes. However, a primary concern with these therapies is their inability to synchronize electromechanically with the recipient myocardium, leading to arrhythmia and aggravating HF symptoms. Our study objective was to use a novel reprogramming strategy to convert human adipogenic mesenchymal stem cells (hADMSCs) first into cardiac progenitor cells (CPCs) and then into conducting Pacemaker‐like cells. Previously, we have shown successful reprogramming of hADMSCs to form CPCs using human transcription factors ETS2 and MESP1. We demonstrated cardiomyocyte phenotype based on gene expression, calcium transients, histology, and polarization wave conduction maps. Interestingly in our current studies, we have optimized a unique cocktail of transcription factors for reprogramming of CPCs into Pacemaker‐like cells using lentiviral vectors. The CPCs treated with transcription factor combinations were initially screened for Pacemaker‐like cells by FACS sorting for mcherry reporter gene specific for pacemaker cells. Following which we assayed these cells for pacemaker marker genes. We observed a robust induction of Pacemaker marker genes, by qPCR gene expression assays. We then validated the functional efficiency of Pacemaker‐like cells in‐vitro through voltage patch clamp recording. Interestingly, the patch clamp recording of the Pacemaker‐like cells exhibited "funny currents" demonstrating the functional characteristic of pacemaker cells. The characteristic of these conduction cells will be further validated by optical mapping in ex‐vivo studies. These studies will facilitate the development of an optimal Pacemaker‐like cell‐based therapy within failing hearts through the recovery of lost contractile and electrical function between cardiomyocytes.


The Data Management System Of Blending ore Quality is according to the process of blending ore and meet the need of modernized corporation. The system apply the principal of database and achieve to record, analyse, print and communicate the data. At the same time, it gives help to managers when they make plan and decision.


There are a lot of chances at a place not far away. If a person knows how to grasp the chances, he/she must catch them. However, there is a valley between here and the chances, so bridges are needed to cross the river. In this paper, the place where the chances are is the Internet. Web pages are filled with chances of entertaining yourself. However, we need a method to obtain this information. Though search engines are used, they never know the human's potential interests. Therefore, we suggest an interface for visualizing user's potential interests so that the users can discover chances from floods of information.


Abstract The effect of varying levels of leaf defoliation on the nodulation and nitrogen fixation of a Virginia and a spanish-type peanut (Arachis hypogaea L.) cultivar was investigated in the greenhouse. Five leaf defoliation treatments - (a) control (no leaflet removal), (b) 25%, (c) 50%, (d) 75%, and (e) 100% - were carried out every 3 to 5 days throughout the growing period. All nitrogen fixation measurements were affected by the defoliation (leaflet removal) treatments. Increased leaf defoliation reduced nodule formation and N2 fixation. The reduction in plant dry weight, nodule number, nodule dry weight, and nitrogenase activity was most severe for the 100% defoliation treatment. Correlation coefficients (r) of N2 fixation measurements and leaf areas and weights were highly significant. The defoliation effect was similar in both experiments and cultivars; however, the Virginia type achieved higher values for all N2 fixation measurements.


The application of advanced computer architecture and software to a broad range of electromagnetic probelm has allowed more accuracte simulations of electrically larger and more complex components and systems that had been previously avilable.


The invention relates to a process for the purification of exhaust gases from processes DRYING WORKING WITH HOT GAS TO BE REFRIGERATED GASES exhaust ARRIVING FROM THE DRYING OF PRODUCTS CONTAINING volatile components, SO THE CONDENSED ASI obtained is subjected to membrane filtration crossflow and part of the exhaust gas PURIFIED ARE gUIDED BACK TO THE DRYING PROCESS. CONCENTRATE RECYCLE obtained SO THAT SUBSTANCES IN can be reused FOR PRODUCING THERMAL ENERGY, OR OTHERWISE. CASH AND ECONOMIC PROCESS IS SUITABLE FOR USE IN REMOVING AEROSOLES, INCLUDING ORGANIC AEROSOLS, IN exhaust gases.


"Wayfinding system" is an interdisciplinary research between the environment design and human interface of information system. The design of EXIT is to efficiently help people to identify the emergency exit when the accident occurred. In this paper, eye tracking techniques are utilized to aided EXIT design in the wayfinding system. The mobile eye tracking was used to collect the human eye movement data in the building where different EXIT designs were displayed. While the stationary eye tracking techniques was used to collect the eye movement data on the same building's EXIT designs on virtual 3D sketches to get the quantitative data comparing with the mobile eye tracker. Finally, some general conclusions were obtained from the views of visual elements selecting, EXIT appearance design and EXIT's placement in the building, which is very valuable and can be commonly referred in wayfinding system. The research methods in the paper is very original and has not been mentioned in other papers of the related fields before, which is well worthy data and empirical methodologies can be introduced in wayfinding and space decision making research.


Background Cognitive–behavioural therapy (CBT) is frequently used as an umbrella term to include a variety of psychological interventions. It remains unclear whether more complex CBT contributes to greater depression reduction. Aims To (a) compare the effectiveness of core, complex and ultra-complex CBT against other psychological intervention, medication, treatment-as-usual and no treatment in reducing depression at post-treatment and in the long term and (b) explore important factors that could moderate the effectiveness of these interventions. Method MEDLINE, PsycInfo, Embase, Web of Science and the Cochrane Register of Controlled Trials were searched to November 2021. Only randomised controlled trials were eligible for the subsequent network meta-analysis. Results We included 107 studies based on 15 248 participants. Core (s.m.d. = −1.14, 95% credible interval (CrI) −1.72 to −0.55 [m.d. = −8.44]), complex (s.m.d. = −1.24, 95% CrI −1.85 to −0.64 [m.d. = −9.18]) and ultra-complex CBT (s.m.d. = −1.45, 95% CrI −1.88 to −1.02 [m.d. = −10.73]) were all significant in reducing depression up to 6 months from treatment onset. The significant benefits of the ultra-complex (s.m.d. = −1.09, 95% CrI −1.61 to −0.56 [m.d. = −8.07]) and complex CBT (s.m.d. = −0.73, 95% CrI −1.36 to −0.11 [m.d. = −5.40]) extended beyond 6 months. Ultra-complex CBT was most effective in individuals presenting comorbid mental health problems and when delivered by non-mental health specialists. Ultra-complex and complex CBT were more effective for people younger than 59 years. Conclusions For people without comorbid conditions healthcare and policy organisations should invest in core CBT. For people <59 years of age with comorbid conditions investments should focus on ultra-complex and complex CBT delivered without the help of mental health professionals.


Illuminating an ER enzyme: We report on the design and synthesis of a fluorogenic chemical sensor (1) to measure sphingosine‐1‐phosphate lyase activity in high‐throughput screening formats, as well as its validation using lyase knockout (Sgpl1−/−) cells.


Although a number of studies have focused on the mediating relationship between HR systems and performance at both a firm-level analysis and a cross-level analysis, only a few have examined the importance of employees' perception in implementing HR systems. Using a massive database that included 6709 employees in 245 manufacturing firms in South Korea, this study examines the relationship between HR systems and two types of firm performance – financial performance and employee job satisfaction – through regression analyses and hierarchical linear modeling. In addition, the study investigates the mediating effect of the employees' positive perception of HR systems. The results indicate that HR systems had an influence on the performance of firms and that the employees' positive perception of HR systems had a mediating effect on the HR–performance relationship in both a firm-level and a cross-level analysis.


Five polypropylene films were prepared having different crystallinity and morphology, the latter having been modified by stretching. They were colored with azo dyes XC6H4NNC6H4N(C2H5)2 (where XH, OCH3, CN, and NO2). The kinetics of the thermal cis-trans isomerization of these dyes has been studied in the range 21–41°C, much above the glass transition temperature of the polymer. The isomerization process was found to be strictly first-order; the kinetic parameter values have been correlated with the free volume extent in the amorphous regions of the matrix. Lightfastness of the dyes in the polymer matrices has been also investigated: It appeared to be more important for the unoriented samples with respect to the stretched ones and substantially independent on the crystalinity degree.


inhibitory GABAergic synaptic transmission through allosteric modulation, thereby contributing to its antiepileptic effects. Several randomized clinical trials demonstrated significant reductions in seizure frequency and increased response rates with fair safety profiles. Long-term extension studies additionally confirmed sustained effectiveness and safety. In terms of potential side effects, studies have indicated the need for careful dosing during the initial titration phase due to the risk of hypersensitivity reactions. This review covers the mechanism of action, pharmacokinetic properties


Sessions I–VII Friday, February 2, 2007 Oral Abstracts: Clinical-Session I 101. RAPID DETECTION OF MYOCARDIAL INFARCTION BY SUB-SECOND, FREE-BREATHING DELAYED CONTRAST-ENHANCEMENT CARDIOVASCULAR MAGNETIC RESONANCE Burkhard Sievers, MD,1 Michael Elliott, MD,1 Lynne Hurwitz, MD,2 Timothy Albert, MD,1 Igor Klem, MD,1 Wolfgang Rehwald, PhD,1 Michele Parker, MS,1 Robert Judd, PhD,1 Raymond Kim, MD.1 1Duke Cardiovascular MRI Center, Duke University, Durham, NC, USA, 2Department of Radiology, Duke University, Durham, NC, USA. Background: An ultrafast, delayed contrast-enhancement cardiovascular magnetic resonance (DE-CMR) technique that can acquire sub-second, 'snap-shot' images during free-breathing (SUB-SECOND) is becoming widely available. This technique provides myocardial infarction (MI) imaging with complete leftventricular (LV) coverage in under 30 seconds. However, the accuracy of this technique is unknown. Methods and Results: We prospectively compared SUBSECOND imaging to routine breath-hold DE-CMR (STANDARD) in consecutive patients. Two cohorts with unambiguFIG. 1. ous standards-of-truth were prespecified: 1) patients with documented prior MI (n = 135); and 2) patients without MI and with low likelihood for coronary disease (lowest Framingham risk category, n = 103). Scans were scored masked to identity and clinical information. Sensitivity, specificity and accuracy of SUB-SECOND imaging for MI diagnosis was 87%, 96%, and 91%, respectively. Compared with STANDARD (98%, 100%, 99%), SUB-SECOND had modestly reduced sensitivity (p = 0.0001), but specificity was excellent (Fig. 1A). Missed infarcts were generally small or subendocardial (87%) (Fig. 1B). Overall, regional transmural extent of infarction (TEI) scores were highly concordant (2083/2294, 91%);however, 51 of 337 regions (15%) considered predominantly infarcted (>50% TEI) by STANDARD were considered viable (≤25% TEI) by SUBSECOND. Quantitative analysis demonstrated moderately reduced contrast-to-noise ratios for SUB-SECOND imaging between infarct and remote myocardium (12.0 ± 7.2 versus 20.1 ± 6.6, p < 0.0001) and infarct and LV cavity (−2.5 ± 2.7 versus 3.6 ± 3.7, p < 0.0001). Conclusions: Myocardial infarction can be rapidly detected by SUB-SECOND DE-CMR during free-breathing with high accuracy. This technique could be considered the preferred


Adaptive linear prediction (ALP) recently has received a great deal of attention for spectral analysis, system modeling, and speech encoding. The conventional approach used to implement ALP involves the computation of a sample covariance matrix for a block of data and solution of an associated set of simultaneous equations to obtain the predictor coefficients. This paper describes an alternate approach that uses the least mean square (LMS) gradient, stochastic-approximation algorithm, commonly used in many other adaptive systems. A complete 8-coefficient hardward system based on this approach has been designed and constructed and is described in this paper. The system consists of an analyzer that computes the eight ALP coefficients in real time and a reconstructor that forms an all-pole model filter using the computed coefficients. Several examples are presented to illustrate the concepts introduced. Each example includes an analytical discussion followed by experimental verification. Applications of ALP for spectral analysis, instantaneous frequency measurement, and speech encoding are discussed and experimental results obtained with the real-time hardware are presented.


Two kinds of new driving waveforms are presented to improve the efficacy,contrast,and resolution of AC-PDP.At first,two kinds of conventional driving waveforms are given.Then,the new waveform is discussed.During each subframe in PDP,there are three periods: the initiate period,the address period,and sustain period.The new waveform can improve the contrast and resolution,can decrease the addressing voltage,and also can decrease the self-erasing discharge in initiate period.The principle of PDP operation and the comparison of different waveform are given in the paper.At last,the experiment result by using the new waveform is given.


Objective To evaluate the value of seminal plasma neutral α-glucosidase in predicting the success of percutaneous epididymal sperm aspiration(PESA) or testicular sperm aspiration(TESA) procedures.Methods Seminal plasma neutral α-glucosidase(NAG) were detected and PESA /TESA were performed in 57 azoospermic patients.The patients were divided into two groups according to the NAG level(Group A: normal group,n = 22 and Group B: low group,n = 35).Results Group A: PESA / TESA were successful in 7 out of 22 patients.Group B: PESA / TESA were successful in 32 out of 35 patients.The successful rate of PESA / TESA of group B was significantly higher than Group A.Conclusions Seminal plasma neutral α-glucosidase is a good predictor of the success of PESA / TESA


Through analyzing the effects of E-commerce on traditional marketing methods,this paper discusses the transformation of business marketing under E-commerce environment.


The rules of electric vehicle fire were summarized based on fatal fires of electric vehicle in recent years.Statistics results indicated that most fatal fires of electric vehicle were induced by charging process,and the primary reasons and mechanism of theelectric vehicle fire duringcharging process were ana-lyzed.Some technical methodologies were proposed to prevent electric vehicle fire occurred on charging process based on the testing results of electric vehicle chargers on the market.


© TOUCH MEDICAL MEDIA 2014 15 Restless legs syndrome (RLS) is a sensorimotor condition that primarily results in sleep disruption and subsequent daytime functional symptoms, particularly for those individuals with moderate-to-severe cases. Recently there has been a shift from using the name 'Restless Legs Syndrome' to using 'Willis–Ekbom Disorder' (WED), in order to address matters of stigma and title inaccuracy.


We have considered an analytical expression for the temperature field of a semi-infinite body that is heated by a circular heat source located at the free surface. Unsteady temperature field is expressed in terms of the Appell and the Srivastava hypergeometric functions. We have studied some special areas in heated body where a non-stationary temperature field is expressed in terms of the Kampe de Feriet function. The obtained expressions have allowed to carry out the separation of the stationary and non-stationary parts of temperature field from each other. Calculations of the steady temperature fields generated by circular or Gaussian sources have been accomplished. Significant quantitative differences in these fields were not found.


Having one or more single-crystal diamond layer is formed by chemical vapor deposition, a synthetic single crystal diamond composition, said layer, as compared with the other layer or similar layer with no impurity, boron ( and such / or carbon isotope) concentration of one or more impurities comprise one or more layers increased. Such compositions, color, intensity, including sound velocity, electrical conductivity, and the suppression of defects, providing a combination improved properties. Furthermore, methods related to preparing such compositions, and systems for use in practicing such methods, and products incorporating such compositions are described.


ABSTRACT. A 14‐year‐old girl with skin rash and acute interstitial pneumonitis is presented. She had been taking carbamazepine for two months. Withdrawal of carbamazepine resulted in a prompt improvement of the clinical picture and a normalization of lung function tests. A hypersensitivity reaction to carbamazepine is suggested and the importance of a skin rash as first sign of a generalized reaction is stressed. Lymphocyte‐stimulation‐tests with carbamazepine were strongly positive in the patient and not in healthy persons nor in patients taking carbamazepine without adverse effects.


Evaluating attributes is the most important stage in consumer decision-making process and culture has a signieeant influence on this stage. The purtlose of this study is to analyze the cross-cultural difference in the evaluation ofhotel selection attributes with Hofstedes theory and to come up with marketing strategy. Data were collected from Japanese and American travellers and were analyzed using t-test. The results of this study revealed that there were differences between two countries in the importance placed on hotel selection attributes. This study confirmed that nationality of travellers have an effect on evaluating hotel selection attributes. Therefore, nationality could be the basis of target marketing strategy.


Exposure to increasing amounts of artificial light during the night may contribute to the high prevalence of reported sleep dysfunction. Release of the sleep hormone melatonin is mediated by the intrinsically photosensitive retinal ganglion cells (ipRGCs). This study sought to investigate whether melatonin level and sleep quality can be modulated by decreasing night‐time input to the ipRGCs.


The Asia Cooperation Dialogue (ACD) is a multilateral organisation consisting of 35 Asian Countries; the Islamic Republic of Afghanistan, the Kingdom of Bahrain, the People's Republic of Bangladesh, the Kingdom of Bhutan, Brunei Darussalam, the Kingdom of Cambodia, the People's Republic of China, the Republic of India, the Republic of Indonesia, the Islamic Republic of Iran, Japan, the Republic of Kazakhstan, the Republic of Korea, the State of Kuwait, the Kyrgyz Republic, the Lao People's Democratic Republic, Malaysia, Mongolia, the Republic of the Union of Myanmar, Federal Democratic Republic of Nepal, the Sultanate of Oman, the Islamic Republic of Pakistan, the Republic of the Philippines, the State of Qatar, the Russian Federation, the Kingdom of Saudi Arabia, the Republic of Singapore, the Democratic Socialist Republic of Sri Lanka, the Republic of Tajikistan, the Kingdom of Thailand, the Republic of Turkey, the United Arab Emirates, the Republic of Uzbekistan, the Socialist Republic of Viet Nam, and the State of Palestine.


Hotel Croatia Cavtat is our most popular hotel, perfect choice for family breaks, romantic holidays or sun filled getaways on the Dubrovnik Riviera.


Wideline acquisition techniques have previously been applied successfully to obtain improved seismic images in areas of poor signal to noise, or structural complexity, where 2D images alone were inadequate. Most such surveys have been conducted onshore with multiple source and multiple receiver lines. A wideline technique has been applied to a transition zone survey in an area with strong source generated noise, potential scattering from near surface anomalies, and moderate structural complexity. Two lines from a 2D transition zone survey were selected for testing this approach in which two additional source lines were acquired parallel to the conventional single source line, resulting in 3 CDP lines. Data processed to account for potential crossdip in the reflections show considerable improvement in the continuity of deeper events in the zone of interest. Sources are inherently cheaper than receivers in the transition zone and the encouraging results of this test with just 3 CDP lines suggests that it would be a useful technique for application in many transition zone areas where obtaining adequate signal to noise is frequently a challenge.


This paper proposes a hybrid modulation method for a dual-output five-leg indirect matrix converter topology. The proposed control technique combines a space vector modulation scheme (SVPWM) applied to the rectifier stage so as to control the input currents and a new digital scalar modulation scheme (DSPWM) designed to control the two loads output voltages. A generalized expression of the output voltage references is also developed showing the capability of the proposed method to control more than two independent loads without requiring additional mathematical development. Furthermore, a new modified expression of the output voltages references is proposed to enable the correct operation of the converter under unbalanced grid voltages. Also, this paper proposes a detailed mathematical analysis that allows evaluating the effect of output loads unbalances on the input current harmonic content. Simulation and experimental results are provided to show the effectiveness of the proposed theoretical investigations and confirm the capability of the proposed method to control multiple drive systems as well as ac input currents.


The yellow spotted mountain newt (Neurergus derjugini) is a critically endangered species restricted to fragmented habitats in highland streams of the middle Zagros Mountain in Iran and Iraq. We examined the species phylogeography by investigating sequences of a mitochondrial fragment of the ND2 gene for 77 individuals from 15 locations throughout the species known distribution. We found relatively high haplotype diversity (0.82 ± 0.025) but low nucleotide diversity (0.0038 ± 0.00022) across all populations. Phylogenetic trees supported monophyly, and the segregation of haplotypes was concordant with the haplotype network. We found a significant correlation between geographical and genetic distances among populations (r = 0.54, P ˂ 0.01), suggesting restricted gene flow. Molecular dating suggested that haplogroups diverged during the early or middle Pleistocene. Bayesian skyline plot provided evidence for an expansion of populations during the Pleistocene-Holocene transition period. Taken together, isolation by distance due to low dispersal capability, habitat fragmentation, and historical factors have shaped the current population structure of N. derjugini.


The savannah of central Brazil occupies 208 million ha, of which about 54 million ha have been converted to cultivated pasture. The aim of this study was to provide the dynamics of evapotranspiration (ET) in a Brachiaria brizantha cultivated pasture in the Brazilian Savannah region at the beginning of the rainy season and determine biological and environmental factors that influence ET by using the decoupling approach. A meteorological station and an eddy covariance system were placed at the studied site. The above-ground biomass production of the B. brizantha pasture responded rapidly to the onset of the rainy season. Leaf area index (LAI) increased from 0·4 to 1·1 between 15 November and 3 December, with a corresponding increase in live biomass. Average ET during the study period was 2·6 ± 0·9 mm. Daily ET was significantly correlated with maximum vapour pressure deficit and precipitation. The average of daytime decoupling factor obtained over 2 d without rain was 0·50 ± 0·06. The B. brizantha pasture deployed in this region showed an intermediate coupling which takes ET to be influenced by both atmospheric conditions and by the available radiation at the canopy.


Within the general problem of mental retardation, the focus has traditionally been on the child's intellectual inadequacy, his feeblemindedness. This is entrenched in the very term used to designate these children, who are usually called feebleminded, or mentally retarded. All the other aspects of the personality of such a child are usually seen as phenomena arising secondarily as a function of the basic intellectual defect. Many investigators do not even see any essential affective and volitional differences between these children and normal children. …


This paper investigates function spaces of partially ordered sets with some directed family of projections. Given a xed directed index set (I;), we consider triples (D; ; (p i) i2I) consisting of a poset (D;) and a monotone net (p i) i2I of projections of D. We call them (I;)-indexed pop's (posets with projections). Our main purpose is to study structure preserving maps between (I;)-indexed pop's. Such a morphism respects both order and projections. In fact, we study weak homomorphisms as well as homomorphisms. In case of (I;) = (N 0 ;), weak homomorphisms are precisely all monotone maps that are non-expansive with regard to some canonical pseudo-ultrametric induced by the given sequence of projections. Weak homomorphisms become then homomorphisms if they are additionally compatible with a so-called weak weight function. Both weak homomorphisms and homomorphisms between two (I;)-indexed pop's turn out to induce (I;)-indexed pop's of their own. We prove that properties such as completeness and compactness of the canonical uniformity induced by the projections are inherited by the function spaces. Moreover, we obtain several cartesian closed categories of (I;)-indexed pop's.


This chapter employs anthropological approaches to examine the cultural influences on our stories about AI. First, the role of biological analogies in conceptions of AI will be highlighted. Second, a more nuanced approach to the anthropomorphism that results from such analogical thinking will be outlined, based on cognitive anthropology. This will allow us to identify specific intentional projections of human attributes that are mapped onto the nonhuman in our narratives. Third, we will consider how these projections come laden with cultural assumptions. Finally, the chapter will consider the parent–child relationship in AI narratives, and employ ethnographic research on the concept of the child to highlight what specific cultural assumptions about the human child, and then, subsequently, the AI child, are present in our stories.


The idea of inductive logic as providing a general, quantitative way of evaluating arguments is a relatively modern one. Aristotle's conception of 'induction' (§παγωγAE) — which he contrasted with 'reasoning' (σνλλογισµÒς) — only involved moving from particulars to universals (Kneale and Kneale (1960: 36)). This rather narrow way of thinking about inductive reasoning seems to have held sway through the Middle Ages, and into the 17th century when Francis Bacon (1620) developed an elaborate account of such reasoning. During the 18th and 19th centuries, the scope of inductive reasoning began to broaden considerably with the advent of more sophisticated inductive techniques (e.g., those of Mill (1843)), and with precise mathematical accounts of the notion of probability. Intuitive and quasi-mathematical notions of probability had long been used to codify various aspects of uncertain reasoning in the contexts of games of chance and statistical inference (see Stigler (1986) and Dale (1999)), but a more abstract and formal approach to probability theory would be necessary to formulate the general modern inductive-logical theories of non-demonstrative inference. In particular, the pioneering work in probability theory by Bayes (1764), Laplace (1812), Boole (1854) and many others in the 18th and 19th centuries laid the groundwork for a much more general framework for inductive reasoning. (See PROBLEM OF INDUCTION for parallel historical developments in philosophical thinking about the possibility of inductive knowledge, most famously articulated by Hume (1739, 1740, 1758).) The contemporary idea of inductive logic (as a general, logical theory of argument evaluation) did not begin to appear in a mature form until the late 19th and early 20th centuries. Some of the most eloquent articulations of the basic ideas behind inductive logic in this modern sense appear in John Maynard Keynes' Treatise on Probability. Keynes (1921: 8) describes a " logical relation between two sets of propositions in cases where it is not possible to argue demonstratively from one to another. " Nearly thirty years later, Rudolf Carnap (1950) published his encyclopedic work Logical Foundations of Probability in which he very clearly explicates the idea of an inductive-logical relation called " confirmation " which is a quantitative generalization of deductive entailment. (See also CONFIRMATION THEORY.) The following quote from Carnap (1950) gives some insight into the modern project of inductive logic and its relation to classical deductive logic: Deductive logic may be regarded as the theory of the relation of logical consequence, and inductive logic …


Quotas and access limitations were introduced to Norway in 1990 to secure future cod fisheries. Comparison of small-scale fishers' practices before and after 1990 pose interesting questions concern...


Bacillus subtilis Tpb55,an antagonistic bacteria isolated from the phyllosphere of tobacco,strongly inhibits the growth of Alternaria alternata(Fries) Keissler,which causes the tobacco brown spot.Crude extract was obtained by precipitation of the cell-free culture of Tpb55 with 90% saturated(NH4)2SO4.The suspension of the precipitate strongly inbibits Alternaria alternata(Fries) Keissler,and it is thermostable,resistant to trypsin,proteinase K,pepsin and organic solvent.Its active pH range is wide,from 5.0 to more than 10.0.One antagonistic peak was obtained from the crude extract of Tpb55 after DEAE-sepharose Fast Flow and Sephadex G-75,which was shoed only single band with 47.8 kD and PI7.2 in SDS-PAGE,respectively.Analyzed the N-terminal partial sequence of protein was Met-Glu-Ile-Phe-Lys-Tyr-Met-Glu-Thr-Tyr-Asp-Tyr-Glu-Gln-Leu-Val-Phe-Cys-.


Dickens and Race offers a unique contextualisation of Dickens's fictional engagements with race in relation to his lesser-known journalism, with wider nineteenth-century debates about differences between humans, with issues of empire, and with the race shows of London. A potentially invaluable resource for students interested in Charles Dickens, Victorian studies, racial difference and empire, and childhood, writes Steven Harkins.


We examine optimal execution models that take into account both market microstructure impact and informational costs. Informational footprint is related to order flow and is represented by the trader's influence on the flow imbalance process, while microstructure influence is captured by instantaneous price impact. We propose a continuous-time stochastic control problem that balances between these two costs. Incorporating order flow imbalance leads to the consideration of the current market state and specifically whether one's orders lean with or against the prevailing order flow, key components often ignored by execution models in the literature. In particular, to react to changing order flow, we endogenize the trading horizon $T$. After developing the general indefinite-horizon formulation, we investigate several tractable approximations that sequentially optimize over price impact and over $T$. These approximations, especially a dynamic version based on receding horizon control, are shown to be very ac...


Iris recognition is a particular type of biometric system that uses pattern-recognition techniques on images of irides to uniquely identify an individual. Here I provide evidence that the iris has a unique pattern which gives us reliable form of identification. In this paper, we will discuss the image quality of irises during iris recognition processing. We used the CASIA-IrisV3-Interval of iris database as input in our system. In this paper, we focused on studying and implementing image quality for each image of CASIA-IrisV3Interval database by adding noise to that database. We used the Hamming Distant technique (HD) to compare each image on CASIA Database with other images in the same database before and after adding noises. When we get the results Of Hamming distance (HD), we will calculate the TPR and FPR to build ROC Carves for evaluating the image quality of CASIA images.


Focusing on the poetry published in the inaugural issues of Household Words, All the Year Round and Once a Week, this chapter considers how reading poetry across periodical titles raises fruitful questions about the nature of periodical poetry and its role in the press, establishing the principles and terminology that will guide the analysis of periodical poetry in the following chapters. The first two sections of the chapter focus on the concept of the inaugural poem, using the poetry of Charles Dickens's Household Words as a case study. The latter half of the chapter examines the use of inaugural poetry in the periodicals that grew out of and in opposition to Household Words, which ceased publication in 1859 due to Dickens's feud with his publishers Bradbury and Evans. In particular, the chapter traces how Dickens used poetry to establish continuity between Household Words and All the Year Round while the proprietors of Once a Week (Bradbury and Evans) distinguished their weekly from Dickens's through illustrated poetry. This close examination of the era's competing weeklies ultimately demonstrates the importance of poetry to the development of a periodical's brand identity.


This paper proposes a machine learning approach for placing control actuators to enhance dynamic performance in power systems with high penetration of renewable energy. The method transforms the placement problem into a classification problem by studying the relationship between system topological, physical and operational features, and dynamic performance related labels. The proposed framework includes four stages: power system setup; dataset creation; feature extraction and analytical model generation, and creating guidelines for system planners. Test results in the IEEE 39-bus system and the IEEE 118-bus system determine the most significant features including inertia, topological, and impedance distributions. This paper also contributes to providing general criteria and guidance for system planners to place the control resources for improving oscillation damping, voltage, and transient stability issues.


The article analyzes the formation of political and legal activity of youth in Ukraine. The main forms of youth political activity are characterized. Considerable attention is paid to the characteristics of the mechanisms and tools of youth participation in the formation and implementation of youth policy. On the basis of the analysis of the legal framework of youth policy, conclusions were made regarding the main trends and specifics of youth participation in political processes, which is expressed through the activities of various public organizations and movements. The purpose of the publication is to study the process of formation of political and legal activity of youth in Ukraine and the role of the state in its formation and development. The methodological basis of the study is based on the use of philosophical, general scientific methods, methods of a systematic approach to analyze the ways and means of forming the political and legal activity of youth, in determining the socio-political situation of youth in Ukraine. The structural-functional approach is used to determine the functions of political activity in the conditions of the transition of society from an authoritarian to a democratic political system. The institutional approach is used to analyze the interaction of the process of political and legal activity and the political system of society, where political institutions, political parties, and public associations play the main role. The normative-value approach was embodied in the analysis of the system of political values, their formation and role in the process of political socialization of the young generation. The scientific novelty of the publication lies in the comprehensive analysis of political and legal activity of youth in Ukraine and its significance for political and socio-economic development. Conclusions. Youth is a dynamic component of modern Ukrainian society. Since young people have to implement the reforms initiated by the state, the state, determining the ways of formation and development of society, focuses primarily on young people, whose potential and knowledge can become a guarantee of progressive development. The political and legal activity of youth is aimed at the formation of a young person who positions himself as a responsible person who respects the rights of other people; is tolerant of political, moral, aesthetic, worldview orientations and preferences; shows a desire for such forms and directions of activity that would consolidate social efforts, make the life of every person meaningful, civilized and promising; is active in the political and legal sphere. Despite the difficult political, economic, and social situation in the country, the public structures of the youth movement are actively developing, preserving their historical traditions, roots, occupying an appropriate place in the political system of society and have now acquired a rather clear outline and certainty, which is due to the presence of support and the implementation of an active policy from the state and local authorities.


AEECENT publication (1) reports the findings of a field team which attempted to follow 1,912 addict patients, living in the New York City area, who were discharged from the Public Health Service Hospital at Lexing¬ ton, Ky., during the period from July 1952 to December 1955. The dischargees were followed until their readdiction to narcotics or until De¬ cember 31, 1956. Subsequently, the followup functions were continued by the New York Demonstration Center, Community Services Branch, National Institute of Mental Health, Public Health Service. Followup was contin¬ ued on a sample from 11 population groups which contained 1,359 of the 1,912 dischargees. The stratified sample of 453, or 33.3 percent, was chosen by a system of disproportionate weights. The number of dischargees so selected and the percentage of the total number con¬ sidered for further followup is presented in table 1. These patients all lived in the New York City area at the time of admission to Lex¬ ington. However, an estimated 38 percent are not native New Yorkers. This study was undertaken to ascertain what happens to the treated narcotic drug addict


Objective To explore the clinical value of the level of granzyme B and perforin mRNA in urine for the diagnosis of renal transplantation patients with delayed graft function (DGF). Methods Twenty-four cases of renal transplantation patients with DGF were included in this study. Seventy-three u-rine specimens were obtained from these patients who received graft biopsies. Among the 24 cases, ureteral obstruction occurred in 2 cases, vascular thrombosis in 1 case, acute CsA intoxication in 3 cases, acute tubu-lar necrosis (ATN) in 7 cases, ATN complicating borderline change in 2 cases, ATN complicating acute re-jection (AR) in 3 cases, AR in 6 cases. Total RNA was isolated from the urinary cells. Messenger RNA (mRNA) encoding the cytotoxic proteins perforin and granzyme B gene were measured with the quantitative polymerase-chain-reaction assay-(RT-PCR). SPSS13.0 software was used for data analysis. Levels of mRNA were log-transformed before analysis. Results The levels of perforin and granzyme B mRNA in u-rine among the ureteral obstruction group, vascular thrombosis group, acute CsA intoxication group and ATN group were very low. There was no significant difference among these groups (P>0.05). However,among the ATN complicating borderline change group 1.22, 0. 97 fg/μg, ATN complicating AR group (1.20±0.39), (1.07±0.30)fg/μg, and AR group(11.13±0. 33), (1.01±0.19)fg/μg, the levels were increased significantly(P<0.001). Conclusion Measurement of mRNA encoding the cytotoxic proteins perforin and granzyme B gene in urinary cells in renal transplantation patients with DGF could be helpful to etiological diagnosis of DGF, and might be used as an index for the appropriate management of the borderline change.

Key words:
Kidney transplantation;  Delayed graft function;  Perforin;  Granzyme B


Information security is important in proportion to an organization's dependence on information technology. When an organization's information is exposed to risk, the use of information security technology is obviously appropriate. Current information security technology, however, deals with only a small fraction of the problem of information risk. In fact, the evidence increasingly suggests that information security technology does not reduce information risk very effectively.This paper argues that we must reconsider our approach to information security from the ground up if we are to deal effectively with the problem of information risk, and proposes a new model inspired by the history of medicine.


The University of North Florida Mechanical Engineering Department currently uses a low speed suction type wind tunnel for pedagogical and research experiments. Wind tunnel experiments range from airfoil and coefficient of drag analysis to convection studies. The wind tunnel was designed and assembled by mechanical engineering students in the spring of 2003 and originally outfitted with a 2-horsepower blower. With this configuration, the wind tunnel achieved test section Mach numbers of 0.15. Due to the demand for higher Mach number testing, the wind tunnel was upgraded to attain test section Mach numbers of 0.30. In addition to a larger blower, considerable flow transitions were added to improve flow quality and reduce losses within the wind tunnel. WIND TUNNEL DESCRIPTION The wind tunnel at the University of North Florida was designed and built by mechanical engineering students in the spring of 2003. The suction type wind tunnel is approximately 18-ft long with an 8-in square test section. The wind tunnel was constructed from 16-gauge sheet metal and built on two moveable wooden frames. Figure 1. Wind tunnel schematic. The wind tunnel can be divided into five distinct sections as seen in Figure 1. The first section is the bell-mouth where the air is drawn into the wind tunnel. The second section is a straight section with a 16-in width where the air is conditioned using tube flow straighteners. The third section is the converging section where the inner width of the wind tunnel is brought from 16in to 8-in. After passing through section three, the air passes through the test section and then through the diffuser at section four. The diffuser is for pressure recovery, the velocity is decreased in order to recover some of the velocity head into pressure head. After passing through the diffuser at section four, the air passes through another straight section at section five before entering the blower. From here on in, the paper will reference each of these sections as their designated section number. The wind tunnel was originally outfitted with a 2-horsepower electric blower from American Coolair as seen in Figure 2. This blower assembly recovered 1.7-in of water at maximum output and enabled the wind tunnel to produce test section Mach numbers of 0.15. During experiments where the blower was operating at maximum design speed, the flow quality would suffer. At high operating speeds the test section velocity would fluctuate as much as 10%. This surging effect would occur because the blower motor could not maintain a constant speed when operating under full load conditions. This decreased the repeatability of data that was recorded in the test section when running lab experiments at maximum speed.


By focussing on a colonial commission of inquiry into the administration of justice in East Africa, this article outlines the major themes that dominated East Africa's legal "world" during the interwar period. The most important of these was the doctrine of indirect rule, which was the prevailing administrative policy during the period. Ultimately, there were two opposing views during this period. The traditional view, held by the judiciary, was that Africans must be "civilised" and integrated into a system of British courts. The opposing view, advocated by administrative officers, held that Africans must be protected against the harmful consequences of any contact with foreign law. One of the central tenets of the doctrine was placing customary courts under the supervision of administrative officers rather than under judges. Directly linked to the resulting legal problems were disagreements between the two sides as to the applicability of English law and customary law. More widely, this detailed study of the Bushe Commission provides an opportunity to view the administration of justice from the perspective of the Colonial Office as well as the colonial state.


The Executive Session on Domestic Preparedness (ESDP) is a standing task force of leading practitioners and academic specialists concerned with terrorism and emergency management. Sponsored by the John F. Kennedy School of Government, Harvard University, and the U.S. Department of Justice, the ESDP brings together experts with operational experience in diverse professional fields that are essential to domestic preparedness -emergency management, law enforcement, fire protection, public health, emergency medicine, national security and defense, and elected office.


In this paper, we analyze the bit error rate (BER) and the throughput of decode-and-forward (DF) relaying with imperfect channel estimation and in the presence of a jammer in the network. We consider a single DF relay scenario with orthogonal cooperative protocols and an active jammer during all the transmission phases attacking the relay and destination nodes in the network. In our analysis, we assume that the complex fading channel coefficients are estimated at the relay and destination levels with errors. We derive the error performance and the throughput of the network then we quantify the impact of channel estimation and the jamming power through the derivation of analytical performance expressions. Our simulation results confirm the accuracy of our analytical BER expression and quantify the performance degradation due to channel estimation and jamming signals. Also, simulation results show the performance of the throughput of the proposed system.


A cloud model evaluation method was proposed according to the characteristics of fuzziness and randomness in road traffic safety evaluation. The evaluation indexes and standards were determined by analyzing the factors effected road traffic safety. The cloud model of each factor on each level was generated by each factor's cloud digital characters. The road traffic safety levels were determined by the weighted average value of the maximum membership. Data measured in the second ring road of Xi'an were evaluated. The results showed that road traffic safety was relatively safe in East Second Ring,South Second Ring and North Second Ring,and the membership of U( Ⅱ) were 0. 404 8,0. 609 8 and 0. 497 6respectively. Road traffic safety was basically safe in West Second Ring,and the membership of U( Ⅲ)was 0. 621 2. The results were compared with Grey evaluation method and Fuzzy Mathematics method.Not only the evaluation method based on the cloud model can determine road traffic safety,but also can determine the membership more accurately.


Wormhole is a kind of attack in Wireless Sensor Network (WSN) that needs not to crack encryption key, which has great harm. Aiming at characteristics of Wormhole attack, the paper presented a kind of wormhole attack defense strategy of WSN based on neighbor nodes verification. Under this strategy, when each normal node received control packet, it will monitor the packet to determine whether it comes from its normal neighbor nodes to avoid Wormhole attack effectively. Modeling and simulation of WSN based on OMNeT++ shows that the AODV added neighbor nodes verification successfully implement effective defense.


Recently, magnetic gears have drawn wide attention due to their inherit merits, such as high torque density and overload protection. In this paper, an analytical calculation based on MMF -permeance theory is adopted to analyze the modulation effect in magnetic gear. After that, an automatic drawing procedure is built to rapidly analyze the parameters. The effects of some key parameters on magnetic gear performance are investigated, including air slot opening to pole pitch ratio Co, magnet-arc to PM pole pitch ratio α and PM thickness hm• In particular, three types of steel pole-pieces are considered, which are radial slots, parallel teeth and parallel slots. At last, a global optimization design is carried out by using differential evolution algorithm, and some useful suggestions are given for the design and optimization of coaxial magnetic gear.


59-year-old, gravida 3, para 3, postmenopausal woman was admitted for transabdominal hysterectomy and bilateral salpingo-oophorectomy because of the finding of a huge (20-week) uterus that was discovered during a physical examination following 1 episode of postmenopausal bleeding. Fractional curettage demonstrated a benign endometrial polyp. The past medical history of this woman included non‐insulin-dependent diabetes mellitus, mild hypertension, and psoriasis balanced and stabilized by medication for the last 2 years. Pelvic ultrasound demonstrated a uterus measuring 10.9 3 12.2 3 11.6 cm and containing a large mass 10.2 3 9.8 3 10.1 cm. Ten months later the uterine size had enlarged further, to 16.4 3 15.2 3 16.7 cm, and its entire cavity was occupied by a tumor with mixed echographic pictures. The patient underwent transabdominal hysterectomy and bilateral salpingo-oophorectomy by lower transverse abdominal incision. The uterus was enlarged, adnexae were normal, and no ascitic fluid was found. The postoperative course was normal, and the woman was discharged on postoperative day 5 in good health.


We establish the asymptotics of blowup for nonlinear heat equations with superlinear power nonlinearities in arbitrary dimensions and we estimate the remainders.


It is common to apply spherical symbols for the map of a study of geography. This molhod is very useful especially when the values to have manifest have a wide range, for it is possible to have developed on a paper having not too great size and by this method we can avoid any adhesion or lying one upon another. But it coines to a question here …… that is a difficulty of reading correctly such a map as using these symbols. It may generally be said that we are liable to estimate spherical symbols smaller than their actual size. To remove this defect of this method is the object of this paper. We are only rely on a solid sensation to estimate each spherical symbol, moreover for ordinary men it is very unfamiliar with such a spherical symbol as having only one white spot. The author deviced a new method to give weight sensation to these spherical symbols. As illustrated in the Fig. 1, we lay some spherical symbols on parallel dot lines and bend down these dot lines on which every symbol stands in proportion to their weight, viz. to their volume. Thus we can read correctly the size of each symbol by the aid of the numbers of these dot lines which warped down. For example A: B: C: D=8: 4: 2: 1 and the numbers of down warping dot lines are 4: 2: 1: 0.5. The author drew a distribution map which manifest the population of cities lying in the Northern Kyusyu, by the method useing spherical symbol having both sansations of weight and solid. (Fig. 2) Then the author deviced some reading tests for this map. He took two groups of men and women; group A, with 28 students of Senior High School; group B, with 22 men and women who are composed of 16 draughtsmen and women and of 6 ordinary men. And two sheets of examination paper were prepared; the A is a map of Fig. 2, and the B is a map that was removed the dot lines from the Fig. 2. The test was performed as below. Let the subjects read both maps of A and B respectively taking a city as the standard of comparison from 22 cities in each map. In these two diagrams the black lines and black dots denote the actual values of population according to the population order of the 22 cities, broken lines and cross points estimation values from the Fig. 3 (the map A, viz. New method) and dot lines and small circles from the map after old method. All these points are arreaged in the ordered population. The largest city is Fukuoka, the second Yawata (the largest city with steel industry in Japan). These two diagrams (Fig. 3 & Fig. 4) tell us many things. (1) Above all the broken line generally goes through passing every point between black point and small circle. This means clearly that the new method is more suitable for the expression of geographical facts and phenomena than the old method. (2) Both subjects (group A and B) have the same tendency of estimation, namely they read the smaller cities some larger than their actual size, whereas they recognized the larger cities smaller. There are a slight diff erence between the group A and B; the parting point of larger and smaller estimation than actural size is higher in the case of group B than the group A. (3) The estimation of group A is a little correcter than group B. This means that the investigation of the students is superior to the adult people.


The bachelor thesis deals with print promotion tools of two selected retail chains on the DIY market. The target shall uncover, which kind of tools are being used, how they are distinguished from each other and how they have changed in the past four years. In the theoretical part, the basic concepts are defined, along with the recourses related to the interpersonal communication and marketing communication in the context with the retail chains. Analytical part is composed of information that covers the evolution of the DIY market together with basic marketing data about a selected portfolio of companies. The analysis of print tools considers the extent and purpose of the research of all of the print tools in the selected retail chains and the evolution of distributed print promotion tools in the past four years. The closing part is composed of suggestions and recommendations, which could ease the way to the target customer.


By presenting useful references to develop the study of teachers' associativism from the socio-historical point of view, the article addresses questions that have become central to the development of our research. It is divided into seven topics. The first topic underlines the contributions of Social History and the second brings attention to the contribution of theories of social movements and it's traditions of research. The third topic focuses on the contributions of political science and the next topic addresses sociological studies of the labor movement. The fifth topic presents some results of the research that bases the present article, while the sixth comments two articles that analyze the production on the subject. The seventh and last topic emphasizes the issue of teacher identities. We conclude by reaffirming the potential of interdisciplinary dialogue to study the theme.


This article explores some of the issues associated with referring patients to a psychologist and outlines new MBS items for psychological treatments.


This paper describes fast, efficient and global optimization method called wind driven optimization (WDO) algorithm for nulling pattern synthesis of uniformly spaced linear array having maximum side lobe level (SLL) suppression, restricted dynamic range ratio (DRR), beam width and null control by controlling the array elements amplitude-only. A broad null is placed in the direction of maximum interference by undesired signals while receiving signal from the desired direction. The WDO is a new nature-inspired evolutionary algorithm derived from to the point movement of the air parcel in the earth's atmosphere. It uses a new learning strategy to update the velocity and position of air packets based on their current pressure values to accelerate the convergence. The pressure (objective) function is based on an exact penalty method. The results are compared with those obtained by other evolutionary algorithm such as bacterial foraging optimization (BFO), plant growth simulation algorithm (PGSA) and bee algorithm. The simulation study demonstrates that the WDO outperforms the three algorithms particularly in terms of minimum SLL, beam width control, DRR, null control and the rate of convergence.


An efficient three-dimensional transient finite element method for calculating the lift, thrust and lateral forces created when a magnetic rotor is both translationally moved and rotated above an aluminum sheet guideway is presented. The rotor field is calculated from an equivalent fictitious magnetic charge sheet formula. The rotor field's effect on the guideway is accounted for by incorporating the field terms into the guideway boundary conditions. This model is validated by comparing it with steady-state experimental and finite element calculations.


Server virtualization is an emerging technology that provides efficient resource utilization and cost-saving benefits. It consolidates many physical servers into a single physical server saving the hardware resources, physical space, power-consumption, air conditioning capacity and man power to manage the servers. Thus virtualization assists "Green Technology". Live migration is an essential feature of virtualization that allows transition of a running virtual machine from one system to another without halting the virtual machine. Live migration extends the list of benefits server virtualization provides. Almost all virtualization softwares now include support for live migration of virtual machine. Live migration is in its infant stage where security of live migration is yet to be analyzed. The usages of live migration and security exploits over it have both increased over time. The security concern of live migration is a major factor for its adoption by the IT industry. In this paper we discuss the attack model on the virtualization system and design and implement a security framework for secure live migration of virtual machines. The framework is an integrated security solution that addresses role based access policy, network intrusion, firewall protection and encryption for secure live migration process.


Liu et al. (1) conclude that Chinese households were a major and underappreciated ambient pollution source and the elimination of residential emissions in Beijing alone decreased PM2.5 concentrations in the city by 22 ± 6%; we accept this idea; however, the residential emissions in Beijing contributed more than 50% during heavy air pollution episodes (Fig. 1). The peaks of hourly PM2.5 and CO concentrations increase significantly and have been transported from south to north at four sites in Beijing, and there is an explosive growth of PM …

[↵][1]1To whom correspondence should be addressed. Email: 15001195306{at}163.com.

 [1]: #xref-corresp-1-1


The "Intelligent Container" is a sensor network used for the management of logistic processes, especially for perishable goods such as fruit and vegetables. The system measures relevant parameters such as temperature and humidity. The concept of "cognitive systems" provides an adequate description of the complex supervision tasks and sensor data handling. The cognitive system can make use of several algorithms in order to estimate temperature related quality losses, detect malfunctioning sensors, and to control the sensor density and measurement intervals. Based on sensor data, knowledge about the goods, their history and the context, decentralized decision making is realized by decision support tools. The amount of communication between the container and the headquarters of the logistic company is reduced, while at the same time the quality of the process control is enhanced. The system is also capable of self-evaluation using plausibility checking of the sensor data.


Acetylcholine (ACh)- and high KCl-stimulated 45Ca uptake into rat uterine segments was inhibited by 3-deazaadenosine (3-DAA) plus homocysteine thiolactone (HCTL), and this inhibitory effect was attenuated by L-methionine (L-Met). Ca-depleted Ringer solution in which uterine muscle had been incubated with L-Met did not enhance the contractile response of another uterine segment to ACh and high KCl in the presence of 3-DAA plus HCTL. These findings together with previous results suggest that the enhancing effect of L-Met on the contractile responses to ACh and high KCl is mainly due to an increase in Ca2+ uptake into the uterine muscle.


The effect of NaCl stress on germination of ten barley cultivars seeds were studied in this paper.The results showed that with NaCl stress content increasing,the inhibitive effect on seed germination obviously increased.These ten barely cultivars have different levels of salt endurance,that is,Dabo30 and ND4994 ·16 were salt tolerant,Dabo37 and Stirling were not salt tolerant and the other cultivars were moderately salt tolerant.


The present invention relates to a method for forming a semiconductor device, in order to prevent a short channel effect that occurs at the gate of the semiconductor element (Short Channel Effect), by recessing the device isolation film protrudes through the active region to form pin (Fin) and this by forming a word line on the semiconductor substrate comprising, by increasing the active area and the contact area of the word line is effective description of the method for forming a semiconductor device that can improve the operating current capability of the transistor.


Approach for measuring intensity distribution in optical field records pattern with vidicon and then displays it on oscilloscope, using vertical sweep as trigger. Single horizontal lines in field can be isolated by using sweep delay feature of oscilloscope.


With increasingly changing climates, measuring the weather on remote, off-grid locations has become more important in order to accurately track emerging weather patterns. Cheap and easy access to meteorological information allows communities and individuals to better manage agricultural development, track localised extreme weather events, and expand knowledge of ground-true weather conditions for remote or hard to access locations. Nowadays, with the growth of modern technology and the rise of the Internet-of-Things, it has become possible to design a long range, low maintenance, affordable, continuously operating autonomous wireless weather station powered off-grid by renewable resources. This thesis explores the feasibility of such a self-supporting wireless station, and attempts to construct a prototype to support the findings. A multitude of solutions are discussed to tackle the different subsystems and their functions, culminating in a proposal for a weather station design. Low maintenance sensors are used to acquire weather data and LoRaWAN is used to send that data over long ranges with a low power draw. The station uses solar energy and li-ion batteries to sustain the system, which are scaled to prevent loss of power. A simple microcontroller unit manages the power and data flows of the system. Long term simulations of the design show the proposed system would be able to operate continuously throughout the year, while measuring every minute. The report also discusses the apparent strengths and shortcomings of the system, and suggests potential improvements that could help the system achieve a better long-term performance.


'Look! Hands off!' : the performance of female exhibitionism in Angela Carter's The Infernal Desire Machines of Doctor Hoffman and Nights at the Circus


A chitin oligomer of formula (I) (where n= 2, 3 or 4) is prepd. by mixing finely ground chitin with conc. hydrohalogenic acid (contg. 1.5-6 mole hydrogen halide por 100g chitin) under ultrasonic irradiation and stirring. As chitin oligomer eg. tetra-N- acetylchitotetraose where n is 2, penta-N- acetylchitopentaose where n is 3, or hexa-N-acetylchitohexaose where n is 4 is pref. Pref. the halogenic acid is of 10-12N concn., the reaction temp. is pref. 35-40≰C and the frequency of the ultrasonic radiation is pref. 10-200 KHz. The chitin oligomer is useful as immunopotentiators, antitumour, antibacterial and antifungal agents.


Stress hyperglycemia occurs frequently in critical care patients and many of the harmful repercussions may be mitigated by maintaining glucose within a ``healthy'' zone. While the exact range of the zone varies, glucose below 80 $mg/dl$ or above 130 $mg/dl$ increases risk of mortality. Zone glucose control (ZGC) is accomplished primarily using insulin administration to reduce hyperglycemia. Alternatively, we propose also allowing glucose administration to be used to raise blood glucose and avoid hypoglycemia.

 While there have been attempts to create improved paradigms for treatment of stress hyperglycemia, inconsistencies in glycemic control protocols as well as variation in outcomes for different ICU subpopulations has contributed to the mixed success of glucose control in critical care and subsequent disagreement regarding treatment protocols. Therefore, a more accurate, personalized treatment that is tailored to an individual may significantly improve patient outcome. The most promising method to achieve better control using a personalized strategy is through the use of a model-based decision support system (DSS), wherein a mathematical patient model is coupled with a controller and user interface that provides for semi-automatic control under the supervision of a clinician.

 Much of the error and subsequent failure to control blood glucose comes from the failure to resolve inter- and intrapatient variations in glucose dynamics following insulin administration. The observed variation arises from the many biologically pathways that affect insulin signaling for patients in the ICU. Mathematical modeling of the biological pathways of stress hyperglycemia can improve understanding and treatment.

 Trauma and infection lead to the development of systemic insulin resistance and elevated blood glucose levels associated with stress hyperglycemia. We develop mathematical models of the biological signaling pathways driving fluctuations in insulin sensitivity and resistance. Key metabolic mediators from the inflammatory response and counterregulatory response are mathematically represented acting on insulin-mediated effects causing increases or decreases in blood glucose concentration. Data from published human studies are used to calibrate a composite model of glucose and insulin dynamics augmented with biomarkers relevant to critical care. The resulting mathematical description of the underlying mechanisms of insulin resistance could be used in a model-based decision support system to estimate patient-specific metabolic status and provide more accurate insulin treatment and glucose control for critical care patients.


Proliferative diabetic retinopathy is characterised by the growth of neovascular tissue, which almost always occurs at the optic disc and/or near the major nasal and temporal vascular arcades, sparing the foveal area. Finkelstein et al. first described neovascular frond at the fovea arising from the perifoveal capillaries. A few other authors like Joondeph et al., Kurz et al., Rajagopal et al. and Seth et al. have also reported similar findings. We report a rare case of unilateral foveal neovascularisation (NVF) in a middle-aged (40 years) woman of Asian origin who presented to us with chief complaints of blurring of vision in both eyes (left more than right) over the past few weeks, which was sudden in onset and progressive in nature. The patient had type 2 diabetes mellitus and dyslipidaemia for the past nine years. Her HbA1c was 10.5 per cent. On examination, her best-corrected visual acuity was 6/12 in the right eye and 6/24 in the left eye. The anterior segment was within normal limits for her age. Meticulous examination of the iris did not reveal any sign of iris neovascularisation. Posterior segment examination revealed proliferative diabetic retinopathy changes in both eyes with vitreous haemorrhage in the left eye only. The right eye was noted to have a whitish tuft at the fovea on biomicroscopy which turned out to be vascular in nature with distorted foveal avascular zone (FAZ) in both multicolor (Figure 1) and reflectance (Figure 2) image. This was confirmed with fundus fluorescein angiography (confocal scanning laser ophthalmoscope-based; Figure 3) and spectral domain optical coherence tomography (Figure 4). Unlike previous reports, except for the recent report by Seth et al., this patient had non-insulin-dependent diabetes mellitus. It is possible that this type of diabetes mellitus is not a predictor of NVF, but rather compromised ocular blood flow and duration and control of diabetes are predictors as reported by Summanen et al. In concordance with Finkelstein et al., Joondeph et al. and Seth et al., we noted macular ischaemia in our case, whereas Kurz et al. and Rajagopal et al. reported cases with perfused macula. Our case had unilateral NVF as reported by Joondeph et al., Kurz et al. and Seth et al., whereas Finkelstein et al. and Kurz et al. reported bilateral cases. We report for the first time multimodal imaging of foveal neovascularisation in diabetic retinopathy. Limitations include a lack of early-phase fundus fluorescein angiography Figure 1. Multicolour image of right eye shows abnormal vessel at the fovea


In order to improve competition in the global economy, China needs the next generation to be more creative, risk taking and independent, which promoted the shift of Chinese Early Childhood Education (ECE) curriculum towards more children-centered, playful and less controlling and academic-oriented. Unlike China, in order to improve childrens' readiness which is considered as a key factors of future academic performance, the US government is striving to shift American ECE curriculum towards more academic-oriented.


To put the people at the core is the basic of a scientific development and the essential purpose of ideological and political education.But there are some disharmonious phenomena in the present education,thus violating the theory of putting the people at the core and weakening the education results.So,guided by the philosophy of Marxism,this essay analyzes the efficiency of ideological and political education,the reasons for these disharmonious problems and ways of achieving a harmony by putting the people at the core.


Lucian's Hippias or The Bath, traditionally considered to be a straight-faced encomium of a historical architect and real-life bath-house of the Antonine period, is now often judged to be a work of satire, though what exactly is being satirized has remained elusive. This article argues that the architect 'Hippias' is closely modelled on Plato's caricature of the sophist Hippias of Elis in the Hippias Minor, and that his bath-house is a comic extrapolation from the sophist's home-made oil-flask and strigil. Lucian's Hippias should be read as a parody of contemporary prose encomia of public buildings.


An increase of B, Ba, Sr, SO4, and Cl concentrations in groundwater of the multi-aquifer system has been noted within the waste dump area of the former chemical works "Tarnowskie Góry". Very high boron concentrations in the Quaternary aquifer (up to 240 mg/dm) and in the Muschelkalk one (up to 116 mg/dm) have been observed. In order to assess current and perspective spreading of boron in the groundwater of the analysed multi-aquifer system, a groundwater flow model (four aquifers: two Quaternary and two Triassic ones, separated by three aquitards) and a solution-transport model were developed. The hydrogeochemical modelling has shown that the share of contaminated Muschelkalk water was equal to 12–22% of the total flow in the Roethian aquifer. A significant differentiation in the intensity of boron migration has been observed within the Quaternary and Triassic aquifers depending on water flow direction. Numerical model simulations have shown that groundwater of the Triassic aquifers, discharged by wells located about 2.5–3 km SW from the waste disposal sites, could be contaminated. The important, large water intakes, situated at a distance of about 5–9 km NW from the sites, are practically safe.


Purpose: Nypa fruticans Wurmb. is one of the underutilized fruit of Malaysia. Antioxidant capacity of immature and mature fruits was evaluated. Findings: Total phenolic and flavonoid content of immature fruits were higher (6.08±0.1 mg GAE/g and 3.3±0.5 RE/g respectively), than mature fruits. Also, immature fruit showed high DPPH radical scavenging activity of 75.7±1.1% and antioxidant capacity (A=1.3), even higher compared with BHT and mature fruits. Practical implications: Both immature and mature fruits exhibited excellent inhibition of RBC hemolysis and moderate hemoglobin oxidation. Value: Hence, this fruit has the potential to be promoted as a natural source of antioxidant.


What would datafication look like seen… 'upside down'? What questions would we ask? What concepts,theories, and methods would we embrace or have to devise? What do we miss if we stick to the mainstream, Western perspective(s)? This paper calls for exploring the question of 'Big Data from the South'. It acknowledges that, while many scholars of various disciplines have started to critically explore the implications of datafication across the social, cultural and political domains, much of this critical scholarship has emerged along a Western axis ideally connecting Silicon Valley, Cambridge, MA and Northern Europe. But how does datafication unfold in countries with fragile democracies, flimsy economies, and impending poverty? Is our conceptual and methodological toolbox able to capture and to understand the dark developments and the amazing creativity emerging at the periphery of the empire? Our South is not just a geographical area, it is primarily a place (and a metaphor) of resistance, subversion and creativity.


FDA HAS ANNOUNCED THAT it will shift the review of biotechnology drugs from its biologics division to its main drug division, the Center for Drug Evaluation & Research (CDER). Currently, CDER oversees traditional pharmaceuticals made using chemical processes. The purpose of the consolidation is to shorten review times for new biologics—drugs derived from living organisms—and to make the review of biologics and traditional chemical drugs consistent. "By carefully combining part of our present biologics review operations responsibilities with our drug review operation, FDA will be optimally positioned to uphold" its reputation for high-quality evaluations, says FDA Deputy Commissioner Lester M. Crawford. The Biotechnology Industry Organization praises FDA's decision. "We are pleased with the Bush Administration's efforts to bring lifesaving drugs to patients faster alongside greater consistency in the drug development and review process," BIO President Carl B. Feldbaum says. One catalyst for this consolidat...


Here we report on UV laser oscillation on colquiriite structure fluoride mixture crystals of Ce3+:LiCaAlF6 (Ce:LiCAF) and Ce3+:LiLuYF4 (Ce:LiLuYF) active media. We report on 800 ps pulse train lasing form Ce:LiCAF in composite cavity and single pulse lasing of 400 ps duration from Ce:LiLuYF in convenient Fabri-Perrot cavity and discuss conditions of pulse shortening in UV active medium by photodynamic processes.


Thirty four patients with breast cancer underwent immediate breast reconstruction following modified radical mastectomy between April 1989 and jaunary 1991. Of the 34 patients, 30 were reconstructed with latissimus dorsi M-C flap (group A) and 4, with rectus abdominis M-C flap (group B). The average age of the patients was 44.5, ranging from 28 to 58 years. In our previous experience with 28 cases undergone modified radical mastectomy without reconstruction, an average time of operation and hospitalization were 152 minutes and 19.8 days respectively. Those data, similarly, were 288 minutes and 20.4 days in group A, and 325 minutes and 26.5 days in group B, respectively. Regarding the hospitalization, there was no significant difference between modified radical mastectomy only and immediate reconstruction following mastectomy with latissimus dorsi M-C flap. Although flap infection in 3 cases and flap necrosis in only one occurred, no sequellae were caused by the reconstruction. Local recurrence and bone metastasis in each one case were detected after 14 months or 12 months. However, the reconstructed breasts did not interfere with the detection or surgical treatment for local recurrence. A questionnaire survey was conducted in about 21 patients over 6 months after the operation. Twenty patients answered that results were satisfactory, and 16 of 20 patients felt that the additional immediate reconstruction was necessary. From these results, it is concluded that immediate reconstruction especially with latissimus dorsi M-C flap should be recommended.


This paper analyses the current situation and predicament of football club operation in China which are caused by the mal-management,high risk cost and unsatisfactory operation.


Journey Treatise of the Erzurum Mufti Osman Bektas Hodja-Verification of Prose, Interpretation and ReviewIn the science of fiqh, Nowadays, Journey Issue which is closely related toworship is to form the basis of discussions as a result of rapid development ofmeans of communication. Therefore Osman Bektas Hodja's Journey Treatiseaim to fill this gap. As well as, this treatise contribute to the discussion of thesubject in different scientific fields. Thus We want to share this treatise, itsinterpretation and reviews to gain new perspectives to solve currentjurisprudence issues and new studies


1 August 2017 When it comes to subsea chemical injection, accurate dosage delivery can make or break an operator's budget. Fast developing technology and methodology in chemical injection metering are making it possible to reliably address the many fl ow assurance challenges specifi c to deepwater production. Until now, traditional low-fl ow chemical injection metering valves (CIMVs) have experienced reliability and accuracy issues due to blockages caused by debris, costing operators millions of dollars in wasted inhibitor costs and nonproductive time (NPT). While injection of medium and high doses of inhibitors (typically for hydrate management) has recently benefi tted from the increased reliability and accuracy, injection of low-dose inhibitors (LDIs) typically for corrosion, scale, or wax can now also benefi t. A new low-fl ow CIMV using a microbore ultrasonic fl owmeter has been introduced by Cameron, a Schlumberger company, completing the PULSE* ultrasonic chemical injection metering valves product line.


Abstract. The purpose of this application, under Article 23.9.3 of the Code, is to conserve the generic name Glossina Wiedemann, 1830 (Diptera, glossinidae), which is a widely used name for a well-established and medically important genus of tsetse flies. It is threatened by its infrequently used senior subjective synonym, Nemorhina Robineau-Desvoidy, 1830. It is proposed that Glossina Wiedemann, 1830 be conserved by reversing the precedence relative to Nemorhina Robineau-Desvoidy, 1830 under the plenary power of the Commission, in the interest of nomenclatural stability.


Fluoro-terminated hyperbranched poly(ether ketone)s (FHBPEKs) with controlled degrees of branching and their linear analogous poly(ether ketone) (LPEK) whose chemical structure and molecular weights were similar to those of FHBPEKs were synthesized and characterized. Depending on the amount of the core molecules, degrees of branching of 0.49 (FHBPEK), 0.62 (FHBPEK−CM01), and 0.67 (FHBPEK−CM02) could be obtained with little variation in the number-average molecular weights of the three FHBPEKs. From the dynamic mechanical analyses, it was investigated that the crossover of the storage modulus G'(ω) and the loss modulus G' '(ω) started to disappear at a critical value (> 0.62−0.67) of the degree of branching, indicating a nearly Newtonian or little entanglement flow. The correlation time, τc, was determined from the shear relaxation moduli and the Cole−Davidson equation, which provided a unique means to evaluate the melt processability on the basis of the molecular mobility. Highly branched structure of FHB...