To the Editor: —A number of ear and throat specialists have found advantage in using trifocal lenses—a distance lens, the requisite presbyopic segment, and another segment cemented at the upper part of the distance lens to give the proper correction when looking through the perforation of the head mirror. Every person whose accommodative power has considerably declined finds that his vision beyond the near point for which his reading glass gives good vision, and inside the distance of 20 feet, is measurably dimmed. This is especially true of persons past 60 years of age. In experimenting with my own eyes, I found that my vision of objects around the office and of persons across the dinner table was much improved by making my distance correction half or three quarters of a diopter stronger than the normal. I then found that street car signs a block away as well as the


Karma-Yoga (Spirit at Work) originated from Srimad Bhagavad Gita, which is considered as the most important sacred text of Hinduism. It means to do something without regard for the result (Nishkama Karma). Karma Yoga molds the fundamental premise of Indian work esteem & departs from Protestant work esteem in terms of practitioner's goal (Karta), i.e., Indians believe work as a duty, a commitment for others that one owes to them in a past life, thus playing out one's obligation lacking longing for common additions will yield higher (supernatural) assistance like freedom (Mukti) from the birth pattern, passing & resurrection (samsara). Though in Modern culture, work is viewed as a way to achieve materialistic increases furthermore, in this manner, Westerners exhaust exertion to have a pleasurable existence (Aisharvya Jeevan). Karma Yoga implies acquiring otherworldly brightening by accomplishing charitable work. This is the highest ideal for work. Not with standing, most of us, who are battling to break free from the iron chains of childishness, track down this ideal exceptionally high, maybe unreachable, from our current degree of being the place where we are joined to numerous things. Karma-yoga is a way that causes redemption through action. Salvation is a permanent condition of the mind. Work has always been the focal point and distinguishing feature of normality. It could be of intrinsic or influential value or both. Instrumental esteem involves, among other things, incentive, pride, & power, which is the expected work result.


TO THE EDITOR: Portal vein thrombosis is an important cause of prehepatic portal hypertension. Clinical diagnosis can be difficult, and the fresh thrombus may be easily missed by conventional ultrasound (1, 2). Nowadays acute portal vein thrombosis (APVT) is increasingly recognized at an acute stage because of the use of Doppler sonography (3). Because the natural course of APVT is unpredictable, its treatment is controversial, ranging from prospective management to surgical intervention (2). We herein report the case of a 29-yr-old woman with APVT due to anticardiolipin antibody syndrome successfully managed with low molecular weight heparin (LMWH) and oral anticoagulation. The patient presented to our emergency room with diffuse abdominal pain. Her medical history was notable for nephrotic syndrome due to focal sclerosing glomerulonephritis. Physical examination revealed tenderness of the upper abdomen on palpation, moderate ascites, and leg edemas. Blood chemistry was remarkable for urea, 75 mg/dl (10–45); uric acid, 7.9 mg/dl (2.4–5.7); -glutamyltranspeptidase, 62 U/L ( 19); leukocytes, 18.77 g/L (4.40–11.30); neutrophils, 12.7 g/L (1.8–7.7); fibrinogen, 441 mg/dl (170–400); total protein, 5.3 g/dl (6.8–8.3); albumin, 1.9 g/dl (3.5–5.3); cholesterol, 493 mg/dl ( 200); and triglycerides, 160 mg/dl ( 150). The remaining blood chemistries, including hepatitis markers, were unremarkable. Paracentesis was performed and yielded 2 L of transudate. Initial abdominal ultrasound workup revealed no evidence for liver cirrhosis on portal hypertension and perfusion of the portal vein, and the hepatic veins were shown to be normal on color-coded Doppler sonography. Ascites was attributed to hypoalbuminemia as a result of nephrotic syndrome, and thrombosis prophylaxis with the LMWH certeparin (0.3 mg s.c. daily) was started. Five days after admission, color-coded Doppler sonography was repeated because of deterioration of the clinical state and revealed a floating fresh thrombus of the portal vein extending into the superior mesenteric vein (SMV). Magnetic resonance (MR) angiography confirmed the diagnosis of portal vein thrombosis extending into the intrahepatic branches and into the SMV and the splenic vein (Fig. 1A). Workup for risk factors favoring portal vein thrombosis revealed high titers of activated antiphospholipid antibodies, whereas protein C, protein S, and antithrombin III were within normal ranges, and screening for factor V Leiden mutation revealed no pathological findings. Therapy with LMWH dalteparin (15,000 IU s.c. once daily) was started. Ascites and symptoms improved rapidly under this treatment, and color-coded Doppler ultrasound showed complete resolution of portal vein thrombosis. Fourteen days after diagnosis the patient was placed on dalteparin (5,000 IU s.c. daily), followed by oral anticoagulation with phenprocoumon. Control MR angiography performed 2 months after remission confirmed complete recanalization and free perfusion of the portal vein, SMV, and splenic vein (Fig. 1B). No further thrombotic events have occurred during 2.5 yr of follow-up. Previous case reports have demonstrated resolution of APVT using different invasive therapeutic options, such as surgical thrombectomy combined with regional thrombolysis (4), selective portal venography with thrombolytic agents (5, 6), or emergency transjugular intrahepatic stent shunt placement combined with fibrinolysis (7). However, the lack of sufficient data does not permit an overall assessment of benefit/risk ratios of these invasive procedures. Complete or extensive repermeation can be achieved with early anticoagulant therapy in more than 80% of patients (1). The best established strategy is intravenous heparinization (2), but we decided to perform full heparinization with LMWH dalteparin. Although the efficacy of LMVH may be comparable to unfractionated heparin based on studies in cardiology and


To determine if the COVID‐19 pandemic has further exacerbated racial disparities in late‐stage presentation of breast, colorectal, lung, and prostate cancers.


Solar cells with multi-junction structures employing various band gap layers are nowadays issue to achieve higher efficiency. We have prepared neutral beam assisted CVD (NBaCVD) deposited a-Si:H which has different oxygen contents as reflector bias and termination capacitor. The oxygen supplied by sputtering of quartz tube(shied for internal ICP antenna) as control of self bias. To control self sputtering of quartz we attached optimized valued capacitor between ends of antenna and ground. As increase of reflector bias directly related the energy of hydrogen, which is reflected from reflector, is increase then the oxygen contents reduced and transform the film structure as amorphous to nano-crystalline. The FTIR, XPS, optical band gap show the changes of oxygen and a-Si:H state as effect of energetic hydrogen reaction with oxygen and Six-Hy bond.


The technical characteristics of XML itself has the advantage in data exchange and sharing,by extending the XML document query language model based on the analysis of retrieval methods,and the use of context information of its technical characteristics and XML tag brings,improve the efficiency of retrieval,meet the basic needs of users' retrieval of information.


The released laser-guided bomb flies along a zero-guidance command programmed trajectory. Once the target reflected laser-energy is received,the bomb will be guided towards the target until impact. During the zero-guidance command flight phase,the direction of the wind-head is along the direction of the velocity vector. And the direction of the gyro-stabilized seeker is along the direction of the body axis. The difference between these two directions is an angle. The value of this angle is α(if wind doesn't exist) or α W(if wind exists). Based on the analysis of the variation characteristics of α,α Wand target acquisition conditions,a comparison of target acquisition probability between these two seekers is studied with equivalent view-angle method. By Monte-Carlo simulation,it is concluded that the target acquisition probability of these two seekers is the same.


Measurement of the second‐order nonlinear optical susceptibility of trigonal selenium yielded d11 = (9.7 ± 2.5) × 10−11 m/V. This value was obtained by cw SHG with a 10.6‐μm CO2 laser at a phase‐matching angle of 5.5° ± 0.3° to the optic axis. Factors affecting this measurement are discussed along with data on absorption, optical activity, and birefringence.


The three articles I was invited to read (Yuen & Grieshaber, Millei & Imre, and Ruffolo in this issue of Contemporary Issues in Early Childhood) describe and respond to the changing ECE policy landscape in Australia, Canada, and Hong Kong. All remnants of the British Empire, these nations, scattered across three different continents, have their own distinct histories and contemporary cultures. They also each have strong representation in the re-conceptualist movement in early childhood education. So I was not surprised that these authors, rather than applauding the increase in services for children and families, take issue with their governments' heightened roles. I learned a lot from their critiques and I was also provoked. Specifically, I pondered the role of academic critique in improving the day-to-day experiences and life chances of children wherever they happen to be in this world.


This paper presents the mathematical development and flight test results of an angle of attack estimation system based on inertial navigation system inputs. The estimator uses these inputs to determine the coefficient of lift required at any instant inflight. Angle of attack is then modeled through a regression analysis based on coefficient of lift, altitude and Mach. Overall correlation of the estimator as tested was generally within 0.5 degrees through 17 degrees angle of attack on an F-15A aircraft. A robustness analysis indicates that the system can be used adequately in maneuvering flight.


The objective of this study was to retrospectively analyse the clinical features about 204 cases of old women with breast cancer who received surgical treatment. The data indicated that 204 cases which were devided into TMN stages Ⅰ 23 (11.3%),Ⅱ 92 (45.1%),Ⅲ 79 (38.7%) and Ⅳ 10 (4.9%), had received surgical treatment with a complication rate of 28.9%. The 3-year and 5-year survival rats were 80.4% and 71.0% in the old women. The data indicated that if correct operations were prformed,the results were satisfied. The age was not a key factor that influenced the prognosis of breast cancer.


Every disorder is embedded within multiple sociocultural aspects, and in mental disorders they acquire paramount significance. Nonetheless and despite the cultural diversity of ancient and modern societies, the consistency of psychiatric reactions to combat stress throughout history is remarkable. The situation in ancient Greece was quite different from the contemporary one. Hippocratic physicians turned a blind eye to a series of worrying conditions they could neither explicate nor treat, but enlightened laypeople noticed mental disorders disregarded by physicians and even looked for ways to assuage them. In ancient Greece, fear, panic, and ensuing short-term psychological consequences were well-known to military men who tried to prevent them by some methods that are considered to be efficient even today. Nonetheless, long-term mental disorders following exposure to battle were almost entirely ignored. The 5th century BC sophist Gorgias seems to be the only author who discussed their nature. Combat-related mental disorders existed more than 2000 years ago, as they do today, and the idea that they could be prevented by means of social conditioning proved to be false. The fact that some modern therapeutic approaches appear to have been used in Greece is reassuring: it suggests that modern Western attitudes to psychological treatment of trauma are not entirely culturally dependent, but rely on universal human processes and may therefore be applied to the treatment of trauma with patients from different cultural traditions. Awareness of the persistence of combat psychological trauma in history may provide insights to different professionals: historians may identify and comprehend allusions to combat trauma in their sources, while mental health professionals may use ancient history to broaden their understanding of the effects of trauma and related treatment. (Less)


In this paper we propose a new type of system explicitly aimed at influencing immediate behavior in an informal, non goal-oriented co-located small group. The state of the group dynamics is automatically assessed in order for the system to continuously plan and deploy minimalist strategies using evocative means to influence behavior, rather than explicit recommendations. A key aspect of our approach is that the main "interaction channel" is left for direct human-to-human interaction, while no large conscious elaboration effort nor actions are meant by the user toward the interface. We present here the concept and a working implementation of a prototype system targeted to a museum scenario. The system has the form of a table in the museum café, and is aimed at inducing a group of friends to talk about the content of their visit to the museum.


During the last hundred years, the Nordic countries have achieved an international reputation for attending to the child as an individual with rights of its own. The purpose of this article is to explore the relationship between left-wing children's literature and the concept of children and children's rights in Sweden around '68. This is of course a rather vast subject and my analysis will therefore focus on two key questions: in what way did the New Left make use of discourses on human rights and children's rights in order to articulate their radical vision of future societies? And how did the New Left mediate and perform their utopian vision of children and children's rights through children's literature? My main focus here is on two influential and interconnected books that imagine what a child is or should be, both of which were published in Swedish in 1969: the radical childcare book Handbok i barnindoktrinering ('Manual of Child Indoctrination') by Frances Vestin (b. 1949) and Nar barnen tog makten ('When The Kids Seized Power'), written and illustrated by the radical Swedish couple Gunnar Ohrlander (1939–2010) and Helena Henschen (1940–2011). Gunnar Ohrlander was a satirical columnist in Aftonbladet, one of the larger daily newspapers in the Nordic Countries. He also wrote for different radical socialist newspapers with close ties to the Communist League Marxists-Leninist fraction, formed at the 1967 communist party congress. His wife Helena Henschen was a graphic designer who successfully illustrated several children's books and was one of the co-founders of the famous anti-capitalistic Swedish design company Mah-Jong in 1966. The ideology of the company's design relied among other things on the idea that soft, colourful clothes would change people in the right direction.


scholars' work into three major periods: 1915–1926, 1922–1941, and 1942–1956. In addition to an introduction as well as a brief epilogue, Making Black History is subdivided into three distinct parts with two interconnected chapters per section. In the opening chapter, the author overviews Woodson's early scholarly life and work as well as the formative years of the ASNLH. The most original argument here is that Woodson's presence at the Lincoln Jubilee in Chicago in 1915 "was one of the first efforts to promote black history to a wider audience" (33). In chapter two, he describes the association as being an advocate of social history and underscores the importance of Woodson's The Negro in Our History (1922). In part two, Snyder maintains that black history was a vital component of the New Negro renaissance and pinpoints the significance of black history pageants to Negro History Week celebrations and black history consciousness building. In part three, the author unpacks the association's discourse surrounding race while also delving into how Woodson viewed World War II and how the association responded to the monumental Brown decision in 1954. The author's most significant contributions include his discussions of Woodson's attendance at the Lincoln Jubilee, the association's influence on the New Negro movement, and black history pageants. He also draws from a host of revealing primary sources. I, for instance, did not know that Woodson called historically-conscious African Americans "wide-awake Negroes" (104). Several points that he raises do deserve further elaboration and theorization. Scholarship by Woodson scholars challenges his belief that "the cause of the proletariat was effectively absent from the association's purview" (8) and that the organization was apolitical. Throughout the book, Snyder also refers to "the association" as if the organization was a monolithic group and that most of the association members whom he profiles in depth were published scholars. Nonetheless, this readable book can serve as a thought-provoking take on the early black history movement for those without expertise in the subject.


The effects of cooling rate and reheating conditions after solid solution treatment on mechanical properties, especially low temperature embrittlement, have been investigated by using Fe-32Mn-7Cr-(0.3-0.4)N, Fe-33Mn, Fe-33Mn-0.3C, Fe-44Mn, Fe-44Mn-0.3C, Fe-58Mn, and Fe-32Mn-7Cr-0.3N-(0.002-0.02)P-(0.0002-0.001)B steels melted in vacuum furnaces. It was found that intergranular fracture was suppressed and toughness increased in all these steels through cooling at an intermediate rate from solid solution treatment temperature or through reheating at around 723-773 K. After such toughening heat treatments no change in microstructures was revealed under an electron microscope and the decrease in tensile strength was very small if any. Autoradiography using α particle fission tracks showed that the grain boundary segregation of boron corresponded to the toughening. The reason for the high susceptibility to low temperature intergranular embrittlement of high Mn non-magnetic steels was also discussed together with the mechanism for the toughening resulting from the heat treatments.


Tracking a portfolio's emissions profile over time is a key requirement for any type of climate-aware investment strategy. The challenge in tracking those profiles is that climate metrics are influenced by not only the emissions of companies in the portfolio but also portfolio managers' decisions, as well as other financial variables such as weights in the portfolio or companies' enterprise values. In this article, the authors develop an attribution framework that allows investors to disentangle these effects. They focus on financed emissions, which aggregate greenhouse gas emissions "owned" by a portfolio's holdings, and financed-emissions intensity, which adjusts financed emissions by dividing it by portfolio value. Their approach is to first calculate contributions by looking at changes in a specific input variable while keeping all other input variables constant. Next, they account for effects of simultaneous changes. The results are organized in an attribution tree that allows for a systematic drill-down into the different effects.


Rogozhin, one of the main characters of Dostoevsky's The Idiot, appears infrequently in the novel, and the author does not give him the philosophical depth of his other great criminal characters. His relationships with Prince Myshkin and Nastasia are nonetheless among the main themes and driving forces of the plot. Driven by jealousy, he eventually murders Nastasia and drives the Prince back to insanity. Rogozhin is presented and given depth by visual imagery, including his gloomy house, the Holbein painting in it, and the knife with which he eventually kills Nastasia. His Old Believer family is also important in defi ning him. The article addresses this visual imagery and Rogozhin's Old Believer roots.


EDITOR—McKinney et al highlight an important issue—namely, the difficulty of obtaining truly informed consent.1 This is a process that most surgeons engage in every day. The current requirement for informed consent is backed by a written record of the consent process in the form of a standard consent form that has …


A random fractal model for the crack propagation of free-machining steelsduring impacting transversely was proposed. The random fractal dimension for impact fracture surface was then calculated. And self-similar fractal dimension was also analysed. Experimental measurement is fair agreement with that of random fractal model proposed.


We report the properties of erbium oxide films grown on Si(100) by low-pressure metalorganic chemical vapour deposition (MOCVD) using a β-dιketonate complex of erbium as precursor. We describe the evolution of the morphology, structure, and electrical characteristics with respect to growth parameters and post-deposition annealing process. Films grown at lower temperatures (∼525°c) are poorly crystalline and those grown at higher temperature (∼ 600°C) are polycrystalline in nature. The effective dielectric constant is in the range of 9-14, while the fixed charge density is in the range - 1x10 11 to -1.93 x 10 10 qC/cm 2 , and flat band voltage in the range of 3-0.1 V. Leakage behaviour was strongly dependent on CVD processing parameters, which have been discussed. The presence of heteroatoms (such as carbon) and their effect on the electrical properties of erbium oxide are discussed.


Schools of Business are diverse in their approach to meeting the Association to Advance Collegiate Schools of Business (AACSB) standards for assurance of learning. Developing a comprehensive assessment plan that includes a process for managing, collecting, analyzing, and reporting student-level assessment data is a daunting task. Assuring the process is faculty driven is even more difficult. Through the creation and evolution of a relatively simple Microsoft Access database, this University was able to develop, implement and manage an assessment plan that meets the AACSB assurance of learning standards, engages the majority of faculty, facilitates the data collection process, generates real-time student-outcome data and trends curriculum improvements over time.


Electrocardiograph (ECG) triggered or gated magnetic resonance methods are used in many imaging applications. Therefore, a reliable trigger signal derived from to the R‐wave of the ECG is essential, especially in cardiac imaging. However, currently available methods often fail mainly due to the artifacts in the ECG generated by the MR scanner itself, such as the magnetohydrodynamic effect and gradient switching noise. The purpose this study was to characterize the accuracy of selected R‐wave detection algorithms in an MR environment, and to develop novel approaches to eliminate imprecise triggering. Vectorcardiograms (VCG) in 12 healthy volunteers exposed to 1.5 T magnetic field were digitized and used as a reference data set including manually corrected onsets of R‐waves. To define the magnetohydrodynamic effect, the VCGs were characterized in time, frequency, and spatial domains. The selected real‐time R‐wave detection algorithms, and a new "target‐distance" VCG‐based algorithm were applied either to standard surface leads calculated from the recorded VCG or to the VCG directly. The flow related artifact was higher in amplitude than the R‐wave in 28% of the investigated VCGs which yielded up to 9–16%false positive detected QRS complexes for traditional algorithms. The "target‐distance" R‐wave detection algorithm yielded a score of 100% for detection with 0.2% false positives and was superior to all the other selected methods. Thus, the VCG of subjects exposed to a strong magnetic field can be use to separate the magnetohydrodynamic artifact and the actual R‐wave, and markedly improves the trigger accuracy in gated magnetic resonance scans. Magn Reson Med 42:361–370, 1999. © 1999 Wiley‐Liss, Inc.


Thermal carbonization of porous silicon (PS) at 820 °C under acetylene atmosphere is an appropriate method for humidity sensing purposes. It produces stable and hydrophilic surface still maintaining originally large specific surface area of PS. We report the temperature dependence of various electrical param‐ eters measured for the thermally‐carbonized PS humidity sensor. Capacitance of the sensor in dry air (6 RH%) is almost constant at various temperatures, whereas in higher relative humidity values, the temperature dependence becomes evident. The resistance variation of the sensor is less dependent on RH as the temperature increases. While the capacitance showed linear behavior as a function of temperature, the resistance had a clear non‐linear temperature dependence. In order to get information about the effects of frequency on capacitance values, we measured a phase angle and admittance of the sensor as a function of frequency at three different temperatures in low and high humidity. According to these results, it is preferable to operate this sensor construction using low frequency (<1 kHz). (© 2005 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)


Entity relation classification is a foundational natural language processing task, which plays an important role in text analysis. At present, most of the methods for Chinese entity relation classification have the problem of segmentation errors, which will cause the accumulation and propagation of errors in the subsequent steps. For this problem, we propose a deep learning framework that integrates word-lever information and character-lever information, which utilizes the efficient fusion of multi-granularity features and gated recurrent mechanism (FGGRM) to dynamically learn semantic information with less effect of segmentation errors. Through the comparison of multiple methods on two datasets, our model shows excellent performance and ability to learn features.


Due to the relationship between stroke volume (SV) and pulse pressure (PP) during lower body negative pressure (LBNP), we hypothesized that PP reflects SV during hemorrhage (HEM). After a 5‐minute baseline, 6 men were exposed to LBNP at ‐15, ‐30, and ‐45 mmHg for 5 minutes at each pressure. After 45 minutes of recovery, three progressive 333‐ml stages of HEM (1 L total) were performed. SV was assessed using a CCNexfin and PP was calculated using an arterial catheter. SV (111 ± 2.1 vs. 77 ± 6.7 mL; p= 0.04) and PP (58±2.7 vs. 41 ± 4.3 mm Hg; p = 0.03) decreased from baseline to ‐45 mmHg LBNP. SV (118 ± 4.4 to 99 ± 6.8 mL; p = 0.06) and PP decreased (58 ± 2.9 to 48 ± 4.9 mmHg; p = 0.06) from baseline to ‐1 L of HEM. PP correlated with SV during HEM (amalgamated r2= 0.98) and LBNP (amalgamated r2= 0.99). There was limited inter‐subject variability in PP vs. SV during LBNP (r2 range 0.57 to 0.99, 5/6 had an r2 >; 0.90), but substantial inter‐subject variability during HEM (r2range 0.21 to 0.99, 2/6 had an r2 >; 0.90). Reductions in PP induced by LBNP or HEM are strongly correlated with SV. However large inter‐individual differences in this correlation during HEM, which may indicate a significantly variable compensatory response in human arterial distensibility, may limit the use of PP as a surrogate for SV during clinical blood loss. Funded by U.S. Army MRMC Combat Casualty Care Research Program Grant # W81XWH‐11–1‐0823.


The enforcement of the gender binary is a root cause of gender-based violence (GBV) for trans people. Disrupting GBV requires that we ensure that 'gender' is not presumed synonymous with White cisgender womanhood. Transfeminists suggest that attaining gender equity requires confronting all forms of oppression that police people and their bodies, including White supremacy, colonialism and capitalism (Silva and Ornat, 2016; Simpkins, 2016). Part of this project, we argue, includes confronting the structures of GBV embedded within digital technologies that are increasingly part of our everyday lives. Informed by transfeminist theory (Koyama, 2003; Stryker and Bettcher, 2016; Simpkins, 2016; Weerawardhana, 2018), we interrogate the ways in which digital technologies naturalise and reinforce GBV against bodies marked as divergent. We examine the subtler ways that digital technology can fortify binary gender as a mechanism of power and control. We highlight how gendered forms of data violence cannot be disentangled from digital technologies that surveil, police or punish on the basis of race, nationhood and citizenship, particularly in relation to predictive policing practices. We conclude with recommendations to guide technological development to reduce the violence enacted upon trans people and those whose gender presentations transgress society's normative criteria for what constitutes a compliant (read: appropriately gendered) citizen.Key messagesViolence against trans people is inherently gender-based.A root cause of gender-based violence against trans people is the strict reinforcement of the gender binary.Digital technology and predictive policing can fortify binary gender as a mechanism of power and control.Designers of digital technologies and the policymakers regulating surveillance capitalism must interrogate the ways in which their work upholds the gender binary and gender-based violence against trans people.


The vitality and dynamic energy which are central to G. M. Hopkins` poetry are expressed with the skillful use of poetic language and rhythm. In this article I have studied the poetic vitality of his nature poems in particular. Lifeless things, animals, human beings--all these are full of vitality and move energetically in his nature poems. In Hopkins` early nature poems Keats` influence is apparent. There are rich expressions of color in "Vision of Mermaids" and "Pied Beauty". This praise of color is soon changed into movement. In "Spring" we can see all kind of creatures moving delightfully and energetically. Even the lifeless things such as clouds or water are moving vitally in Hopkins` nature poems. The cloud in "That Nature is Heraclitean Fire" is walking through the air like a marching army. And the bird in "The Windhover" flies in well controlled movements like that of a skater. All creatures in the world are moving delightfully under the grace of God. Human beings in his poems are naive and strong rather than refined and handsome. The blacksmith in "Felix Randal", the farmer in "Harry Ploughman" and the laborers in "Tom`s Garland" are all men of simplicity from the lower class and full of vitality. In his nature poems, all creatures, lifeless things, human beings are full of energy. This is related to `inscape`, his unique term and it most vividly appeares in movement. This movement is also well expressed by his distinguished rhythm and imagery. In reading his poems, we can feel the movement of the poem itself. Al poetic devices (dixon, rhythm, syntax and imagery) were used to achieve this effect. Hopkins` poems are all successful in their poetic inscape.


Data of the negative effect of high concentrations of aldosterone in the blood for cardiovascular disease, which served as the theoretical basis for wider use in clinical practice of the drugs belonging to the class of aldosterone receptor blockers is presented. Evidence-based data on efficacy and safety of aldosterone receptor blockers, which were obtained in the course of several randomized clinical trials is performed. Particular attention is paid to aspects of the clinical use of selective aldosterone receptor blocker eplerenone, including current data, which makes reasonable extension of indications for its use in treating patients with chronic heart failure. Data on indications of eplerenone use in patients with hypertension, especially in the case of associated target organ damage is presented.


This study aims to detect the probable effects of the modernization of the European Union (EU) Turkey Customs Union upon the international road transportation sector. Izmir region has been selected as a research area. Izmir is located in the Aegean region, which is the third biggest city and second biggest port of Turkey. With its developed industry due to the region's raw material resources, qualified labor force, and wide range of transportation opportunities, Izmir is one of the important trade centers, ranking second after the Marmara Region in terms of industry. Closeness to the landlocked centers with high processing capacities such as Manisa, Denizli, Aydin, Mugla, Bursa, Usak, Kutahya, and the presence of around 1,700 companies with international capital makes Izmir more critical for the logistics sector. Thus, it is considered an acceptable sample area for the research. A semistructured interview technique has been used in the investigation. According to the results of interviews with 19 international road transporters in Izmir, the modernization of the Customs Union will increase Turkey's competitiveness of trading in goods and services with the EU countries. Removing the obstacles like visa problems, limitations on the free movement of drivers and transportation services, transit tolls that the Turkish road transport companies face in the EU member states, the modernization of the Customs Union will benefit both Turkish road transporters and exporters, as well as increase trade volume between the sides.


INTRODUCTION: The purpose of our study was to evaluate the predictive value of uterine content ultrasound measurements in predicting medical management failure of early pregnancy loss. METHODS: We conducted a retrospective cohort study in a single university-affiliated hospital center on all women discharged from the emergency department with a diagnosis of early pregnancy failure who were managed with misoprostol. Only women with ultrasonographic data available for review between 2011 and 2013 were included. Exposure of interest consisted of uterine cavity measurements including: anteroposterior distance, longitudinal distance, transverse distance, and uterine cavity volume. Outcome was defined as need for dilatation and curettage (D&C) or unplanned return to the emergency department. Logistic regression was used to identify ultrasonographic measurements independently associated with failed medical management. RESULTS: Among 823 women presenting to the emergency department with first-trimester bleeding, 226 met inclusion criteria. Of all measurements evaluated, anteroposterior distance was found to be independently associated with D&C and unplanned return to the emergency department. When using an anteroposterior distance cutoff of 15 mm, women were more likely to require D&C, 2.58 (1.27–5.24; P=.01) and to have an unplanned return to the emergency department, 2.63 (1.41–4.88; P=.002). In women with an anteroposterior distance below 15 mm, 87.7% had successful medical management of early pregnancy loss and 80.0% did not require an unplanned return to the emergency department. CONCLUSION: Although there is a need for further validation, using an anteroposterior distance cutoff of 15 mm in a hospital-based population of women with early pregnancy failure may be helpful in selecting patients who can safely be managed medically.


Traffic engineering manuals contain the standards, warrants and procedures for implementation of the traffic engineering aspects of a highway program. Because it has the most direct impact on the driver, traffic engineering suffers the most scrutiny when plaintiffs try to build a case against a highway department. This paper examines the California experience with tort cases involving mandatory duty to follow traffic engineering manuals resulting in negligence per se and those where the plaintiff contends that although a mandatory duty is not established, the traffic engineering manual provision is nevertheless relevant on the issue of standard of care.


Recent years witnessed the general usages of smart mobile devices together with the globalization of mobile messenger market. The important of glocalization is emphasized for the critical factor for the overseas markets. This study reviewed cases Line in the markets of Japan, Spain and Indonesia and analyzed the globalization efforts and the degree of localization by comparing to the main competitors. The results show that emergent approach and balancing between globalization and localization made Line successful in overseas markets. Findings of this study enable mobile-based firms to establish glocalization strategy by providing the implication related to the importance of appropriate localization and in time response to dynamic and differentiated requirements of each country.


Quasi-periodic oscillations, often present in the power density spectrum of accretion disk around black holes, are useful probes for the understanding of gravitational interaction in the near-horizon regime of black holes. Since the presence of an extra spatial dimension modifies the near horizon geometry of black holes, it is expected that the study of these quasi-periodic oscillations may shed some light on the possible existence of these extra dimensions. Intriguingly, most of the extra dimensional models, which are of significant interest to the scientific community, predicts the existence of a tidal charge parameter in black hole spacetimes. This tidal charge parameter can have an overall negative sign and is a distinctive signature of the extra dimensions. Motivated by this, we have studied the quasi-periodic oscillations for a rotating braneworld black hole using the available theoretical models. Subsequently, we have used the observations of the quasi-periodic oscillations from available black hole sources, e.g., GRO J1655-40, XTE J1550-564, GRS 1915 + 105, H 1743 + 322 and Sgr A* and have compared them with the predictions from the relevant theoretical models, in order to estimate the tidal charge parameter. It turns out that among the 11 theoretical models considered here, 8 of them predict a negative value for the tidal charge parameter, while for the others negative values of the tidal charge parameter are also well within the 1-σ confidence interval.


At the very beginning of Feeling Global, Bruce Robbins remarks that "it is not a surprise or scandal that any given version of internationalism turns out to be local and conjunctural rather than universal" (7). Not a surprise, because it's axiomatic for recent thinking about culture that every attempt to transcend the limits of a "local" standpoint is doomed from the outset. Not a scandal, because Robbins thinks he can fashion a version of left-wing internationalism that has moral force in spite of this. It's a difficult task, and Robbins not only refuses to cut corners, he insists on describing each corner in detail before carefully navigating his way around it. Had he been a sailor on Odysseus's ship, he would have thrown the Sirens megaphones before attempting to sail past their island.


On 2 April 2017 Louisiana saw one of its largest tornado outbreaks since 1950. The day saw a total of 21 tornadoes, six of which were classified as significant (EF2+). This extreme event resulted in an estimated 4.2 million dollars in damage and two fatalities. A climatology of Louisiana individual tornado days dating back to 1950 ranked this event second for total number of tornadoes (21) in a day and second for number of significant (EF2+) tornadoes (6) in a day. To assess the overall impact of this outbreak, the Destruction Potential Index (DPI) was used to compare both the overall number and strength of tornadoes to previous events. The 2 April 2017 event had the highest DPI for the state of Louisiana since 1950. Comparisons made to tornado days in nearby states in the region also highlight the significance of this event. The synoptic conditions of 2 April 2017 were compared to a 25-member synoptic scale composite of past Louisiana tornado days with six or more tornadoes. The composite highlighted anomalies in synoptic ingredients that contribute to tornado outbreak environments. Most notably, the synoptic structure consisted of a more meridional flow pattern, which allowed for stronger moisture transport, low level shear, deep layer shear, and increased thermal advection. This produced an optimal mesoscale environment with high instability and storm-relative environmental helicity. The meteorological significance of this event with respect to Louisiana stems from the uncommon combination of a high shear/high CAPE near-storm environment in a southern tornado outbreak. The high shear/high CAPE environment largely responsible for the 2 April 2017 Louisiana tornado outbreak is more commonly observed in Great Plains tornado outbreaks.


In this paper, the typical fault estimation and dynamic analysis are presented for a leader-follower unmanned aerial vehicle (UAV) formation system with external disturbances. Firstly, a dynamic model with proportional navigation guidance (PNG) control of the UAV formation is built. Then, an intermediate observer design method is adopted to estimate the system states and faults simultaneously. Based on the graph theory, the topology relationship between each node in the UAV formation has been also analyzed. The estimator and the system error have been created. Moreover, the typical faults, including the components failure, airframe damage, communication failure, formation collision, and environmental impact, are also discussed for the UAV system. Based on the fault-tolerant strategy, five familiar fault models are proposed from the perspectives of fault estimation, dynamical disturbances, and formation cooperative control. With an analysis of the results of states and faults estimation, the actuator faults can be estimated precisely with component failure and wind disturbances. Furthermore, the basic dynamic characteristics of the UAV formation are discussed. Besides, a comparison of two cases related to the wind disturbance has been accomplished to verify the performance of the fault estimator and controller. The results illustrate the credibility and applicability of the fault estimation and dynamic control strategies for the UAV system which are proposed in this paper. Finally, an extension about the UAV formation prognostic health management system is expounded from the point of view of the fault-tolerant control, dynamic modeling, and multifault estimation.


Three main genetic diversity hotspots were identified in a survey of the genetic variability of the populations of the candy barrel cactus Echinocactus platyacanthus, a protected and highly sought-after cacti for ornamental, culinary and livestock water source in the Chihuahuan Desert Region, Mexico. This study identified one southern, one central, and one northern population in the Chihuahuan Desert Region as first priorities for conservation based on the analysis of a matrix of 4 ISSRs for 183 individuals from 10 localities along the 900 × 300 air km polygon of the geographic distribution of the species. The genetic structure of the 183 individuals from the 10 populations studied, showed a high degree of genetic differentiation for each of the localities with low gene flow, making each of these populations important for conservation actions. The isolation by distance analysis showed that other factors apart from the geographic distance could be playing an important role in the differentiation of the genetic structure of the populations. The UPGMA tree derived from the genetic distance matrix showed that the central and the southern populations conform a mega genetic population clearly separated from the northern populations, each with its own genetic signature.


Currently, there are three undergraduate majors in College of Culture and Media of Sichuan University of Arts and Sciences, namely, cultural industry management, broadcasting and hosting, and radio and television director. Those three majors are all applied ones, which require the improvement of practical teaching in the process of major construction and student cultivation. Practical teaching system is under construction in College of Culture and Media, which mainly consists of course practice, project practice, industry practice, social practice and competition practice.


The article is devoted to studying the peculiarities of reflexivity of children of senior preschool age with different experience in solving «problems of meaning». Solving «problems of meaning» with the help of adults is a tool for the development of reflexivity of children of senior preschool age. The children who had an experience of solving «problems of meaning» discover the ability to see different situations in a more complex way and use constructive methods for solving problems. They show processional behavior that is based on careful attitude to other people.


This paper proposes a new method for enhancing the contrast as well as brightness of color images, based on orthogonal D4 Wavelet transform human visual system and also considers distinction between the background and foreground of the images. The RGB (Red, Green, and Blue) values of each pixel in a color image are converted to HSI (Hue, Saturation, and Intensity) value. On the S components of the color image, the orthogonal D4 Wavelet transform is applied in the appropriate blocks. It can be detected by suitable edge detector. The orthogonal D4 Wavelet transform decomposes the S component into detail and approximate components. Then the contrast as well as brightness enhancement on the approximate component based on the human visual system is applied. For I component histogram equalization is applied. IWT is applied on the detail and modified approximate component for the selected block. The old H, modified S and modified I, are then converted into the RGB color space. The effectiveness of the proposed method is demonstrated experimentally.


Abstract Background Prediction error is the mismatch between expected and obtained outcome, and psychosis has been linked to aberrant striatal prediction error signal. Several lines of evidence indicate alterations of the glutamatergic system to be involved in the pathophysiology of schizophrenia. We have previously reported abnormal thalamic glutamate levels at illness onset in schizophrenia patients driven by increased levels in non-responding patients, and that glutamatergic levels in the thalamus in twins dis- or concordant for psychosis were heritable and associated with the illness. Glutamatergic abnormalities may affect processing of prediction error; however, it remains unresolved if prediction error is affected by antipsychotic treatment, and to which extend treatment effect on prediction error is predicted by glutamatergic levels in patients characterized as responders or non-responders. Here, we explore treatment effects of aripiprazole on striatal prediction error signal in initially antipsychotic-naïve patients characterized as responders and non-responders and relate the findings to thalamic glutamate levels. We hypothesize a different treatment response in prediction error signal in responders and non-responders, and an association to baseline glutamate levels. Methods Thirty-three patients (age 22 ± 4 years) and 33 healthy controls (HC) matched on age and gender underwent functional Magnetic Resonance imaging (fMRI) and magnetic resonance spectroscopy (1H-MRS) (3T) at baseline and after 6 weeks of treatment with aripiprazole. Prediction error related brain activity was examined using a Monetary Incentive Delay Task. Glutamate levels were estimated in the left thalamus and analyzed using LCModel. In patients, symptom severity was assessed with the Positive and Negative Syndrome Scale. The Andreasen criteria defined responders (N=10) and non- responders (N=23). Repeated measures analysis of variance was used to test the effect of time in prediction error signal with group (responders vs non-responders vs HC) as between subject factor and time as within factor. Analysis of variance, two sample t-test and paired sample t-test evaluated group differences at baseline and follow up. In a multiple regression analyses we investigated the influence of baseline glutamate levels, symptom severity and p-aripiprazole on changes in prediction error signal in both responders and non-responders. Results Repeated measures analysis of prediction error showed an effect of group (p=0.007) and no effect of time (p=0.29) or interaction (p=0.29). The effect of group was explained by an abnormal increased prediction error signal in responders (p=0.047) and non-responders (p=0.011) compared to HC at baseline, which was normalized at follow up in responders (p=0.94) but not in non-responders (p=0.02) compared to HC. Changes in prediction error signal following treatment were predicted by glutamate levels in non-responders (p=0.03) but not in responders (p=0.85) whereas p-aripiprazole and symptom severity did not predict changes in prediction error signal (all p>0.05). Discussion The findings suggest that treatment with a partial dopamine agonist normalizes prediction error signal in patients characterized as responders. Thalamic glutamate seems to play a role in the neural coding of prediction error in patients characterized as non-responders, where increased levels of glutamate in the thalamus seems to predict a less pronounced changes in prediction error signal.


Review(s) of: Beyond the veil: The adventures of an American doctor in Saudi Arabia, by Seymour Gray, M.D., Harper and Row.


A major drawback to accurate diagnosis and treatment of inflammation-driven prostate cancer (PCa) progression is our limited understanding of the molecular mechanisms underlying aberrant inflammation signaling in PCa patients. Since asymptomatic chronic inflammation is hard to diagnose, we do not have adequate knowledge of how specific genes within the inflammatory cascade drive PCa aggressiveness. Hence, an integrative genomic approach may provide us with effective prognostic and diagnostic tools to manage inflammation-driven PCa progression. The aim of this study was to characterize inflammation-associated hub genes as predictors of PCa progression and investigate the effect of aberrant signaling of interleukin-1 receptor-associated kinases (IRAKs) on prostate tumorigenesis. WES and RNA-seq datasets from a total of 726 PCa patients, stratified into subtypes: primary PCa (PPC; n=493), metastatic PCa (MPC; n=150) and the castration-resistant PCa (CRPC; n=52) and neuroendocrine PCa (NEPC; n=30) from 3 cohort studies were acquired from cBioPortal. A bioinformatics pipeline was designed to analyze the datasets. Weighted gene co-expression network analysis (WGCNA) was used to construct gene co-expression networks and identify inflammation hub genes associated with PCa progression. The top inflammation hub genes, such as ILR1, TLRs, IRAK1-4, and NF-kB were validated. IRAK1-4 hub genes were found to be differentially expressed and genetically altered in NEPC and CRPC (>40%) compared to PPC and MPC ( Citation Format: Saheed Oluwasina Oseni, Mirjana Pavlovic, James Hartmann, James Kumi-Diaka. Integrative genomic characterization and CRISPR-mediated gene editing studies identify IRAKs as novel therapeutic targets for inflammation-driven prostate tumorigenesis [abstract]. In: Proceedings of the Annual Meeting of the American Association for Cancer Research 2020; 2020 Apr 27-28 and Jun 22-24. Philadelphia (PA): AACR; Cancer Res 2020;80(16 Suppl):Abstract nr 995.


Abstract These joints are used when the designer and contractor anticipate difficulties during the construction of overlap joints. They were not included in the PN EN 1993-1-8 in full scale. Resistance assessment of such joints is presented in accordance with standard rules. The results were compared with the experimental studies carried out at the "Mostostal" Centre; while the former research activities and the legitimacy of the proposed method of assessing the resistance of these joints was confirmed. This is an example of an overlap joint calculation.


The article analyses the features of planning of the special physical training of the young football players aged 11-12 years old taking into account their game role. The indicators characterizing the special physical fitness of the footballers of educational and training groups are presented.


The laminar—turbulent transition of the Taylor—Görtler (TG) vortex flow in the clearance between two concentric spheres with only the inner sphere rotating (spherical Couette flow) is investigated by velocity measurement and simultaneous spectral and flow-visualization measurements by measuring the intensity of light scattered by the aluminium flakes used in flow visualization in the case of a relatively small ratio of the clearance to inner-sphere radius (clearance ratio β = 0.14). An azimuthal velocity component has been measured by a constant-temperature hotwire anemometer at two different colatitudes (meridian angles) θ; θ = 80° and 90° (the equator). A critical Reynolds number, some transition Reynolds numbers, flow regimes and flow states are obtained by the simultaneous spectral and flow-visualization measurements. The flow state is expressed by the number of toroidal TG vortex cells N, that of spiral TG vortex pairs Sp, the wavenumber of the travelling azimuthal waves on the toroidal TG vortices m and the wavenumber of shear waves SH. The mean velocity distribution and the characteristic values of the fluctuating velocity, such as autocorrelation coefficient, power spectrum and turbulence intensity (r.m.s. value), are considered over a great range of Reynolds number Re. Three kinds of fundamental frequencies of the velocity fluctuation are discovered and their characteristics are clarified by means of the velocity measurement and the simultaneous spectral and flow-visualization measurements. The three kinds of fundamental frequencies expressed by fS, fW and fH correspond to the spiral TG vortices, the travelling azimuthal waves and the shear waves, respectively. These fundamental frequencies are independent of both θ and wall distances from the inner sphere, but depend strongly on Re. Although the rotation frequency of the travelling azimuthal waves (or wave speed) in the circular Couette flow decreases monotonically with increasing Reynolds number until it reaches a plateau, the values of the rotation frequencies of the spiral TG vortices, the travelling azimuthal waves and the shear waves in the spherical Couette flow, fS/SP, fW/m and fH/SH, are nearly constant as the Reynolds number is increased, and differ slightly from one another.


The combustion of chloroethane is modeled as a stirred reactor so that we can study critical emission characteristics of the reactor as a function of residence time. We examine important operating conditions such as pressure, temperature, and equivalence ratio and their influence on destructive efficiency of chloroethane. The model uses a detailed chemical kinetic mechanism that we have developed previously for C{sub 3} hydrocarbons. We have added to this mechanism the chemical kinetic mechanism for C{sub 2} chlorinated hydrocarbons developed by Senkan and coworkers. In the modeling calculations, sensitivity coefficients are determined to find which reaction-rate constants have the largest effect on destructive efficiency. 24 refs., 6 figs., 1 tab.


Australia has a rich history of immigration. Historically, immigrants have often met with negativity and distrust (for example, Greek, Italian and Vietnamese immigrants). Evidence is now accumulating that many Australians also are critical of the latest 'wave' of asylum seekers. In the present study, we were interested in the effect of the wider society on the social inclusion (or not) of asylum seekers using an ecological framework and in particular focusing on the 'macrosystem' and 'location'. To do this, we examined negative attitudes toward asylum seekers as well as their correlates collected from 649 members of the West Australian community. Our results indicate that participants who reported more negative views about asylum seekers were also significantly more likely to report a fear of terrorism. Additionally, there were significant location differences in the strength of this relationship. Together with past research, our results indicate that context can greatly impact on the well-being of new Australians.


Background: Laparoscopic resection is considered the gold-standard approach for both benign and malignant neoplasms that arise in left hepatic lobe. Laparoscopic left lateral segmentectomy (LLLS) by means of an intrahepatic approach has emerged as an interesting alternative because it is fast and easy to perform and is associated with infrequent intraoperative bleeding. Aim: To report on a series of six patients who underwent LLLS by means of an intrahepatic Glissonian approach (IHGA) performed by a single surgical team at Santa Lucia Hospital, Brasilia, Federal District, Brazil. Patients and Methods: Six patients underwent LLLS between January 2009 and June 2011. The median age was 41 (range: 21 to 53 years). There were four women and two men. The etiologies of the lesions were: focal nodular hyperplasia (n=2), giant hemangioma (n=1) and metastasis (n=3). The mean lesion diameter was 4.6 cm (range 1.8 12 cm). Results: The mean duration of the procedure was 140 minutes (range 100-200 minutes). Mean intraoperative blood loss was 150 ml (range 50-600 ml). There was no mortality and the morbidity rate was 15%. The median hospital stay was three days (range 2-7 days). The median length of time taken to return to day-to-day activities was 12 days (range 7-30 days). Conclusion : LLLS by means of an intrahepatic Glissonian approach (IHGA) should be considered to be a good option for treating hepatic tumors located in the left hepatic lobe. This approach provides a safe and fast option that avoids large blood loss.


Abstract A rather consistent Wnding in studies of perceived (imagined) compared to actual movement in a reaching paradigm is the ten-dency to overestimate at midline. Explanations of such behavior have focused primarily on perceptions of postural constraints andthe notion that individuals calibrate reachability in reference to multiple degrees of freedom, also known as the whole-body ex plana-tion. The present study examined the role of visual information in the form of binocular and monocular cues in perceived reachabil-ity. Right-handed participants judged the reachability of visual targets at midline with both eyes open, dominant eye occluded, andthe non-dominant eye covered. Results indicated that participants were relatively accurate with condition responses not being s igniW-cantly diVerent in regard to total error. Analysis of the direction of error (mean bias) revealed eVective accuracy across conditionswith only a marginal distinction between monocular and binocular conditions. Therefore, within the task conditions of this experi-ment, it appears that binocular and monocular cues provide su Ycient visual information for e Vective judgments of perceived reach atmidline. 2005 Elsevier Inc. All rights reserved.


An imaging apparatus for imaging a subject image pickup element having, according to one embodiment of the present invention, when the instructions for removing foreign matter adhering to the vicinity of the imaging element and performing a cleaning mode and the cleaning mode, by detecting the voltage supplying circuit detects the battery remaining amount of battery power to the imaging apparatus, in the case where the battery remaining amount is less than a first predetermined amount, an alarm lamp or by sounding body. Further, when the battery remaining amount of battery is a first predetermined amount or less, to prohibit movement of the cleaning mode. Further, when the cleaning mode is executed, when the remaining battery level is lower than the first predetermined amount of the second predetermined value or less, the mirror drops can not be cleaned.


In this paper, we propose the Cold-start Resistant and Extensible Recommender (CoRE), a novel recommender system that was developed as part of collaborative research with Ryanair, the world's most visited airline website. CoRE is an algorithmic approach to the recommendation of hotel rooms that can function in extreme cold-start situations. It is a hybrid recommender that blends elements of naïve collaborative filtering, content-based recommendation and contextual suggestion to address the various shortcomings which exist in the underlying user and product data. We evaluated the performance of CoRE in a number of scenarios in order to assess different aspects of the algorithm: personalization, multi-model and the resistance to the extreme cold-start situations. Experimental results on an authentic, real-world dataset show that CoRE effectively overcomes the different problems associated with the underlying data in these scenarios.


Introduction: Optimal CB unit selection guidelines recommend consideration of CD34+ cell dose & 8-allele donor-recipient HLA-match. How graft characteristics for these parameters vary by patient (pt) race/ ethnicity, however, is not known.
 Methods: We analyzed the infused graft & back-up unit cryopreserved total nucleated cell (TNC) x 107 & CD34+ x 105 cell content, the cell dose (incorporating pt weight), & 4-6/6 & 8-allele HLA-match by pt ancestry in CB transplant (CBT) recipients transplanted 1/2014-6/2018. Units were chosen based on banking practices (e.g. RBC depleted, standard cryo volumes), TNC & CD34+ dose & 4-6/6 & 8-allele HLA-match with dose usually taking priority over match given pt size at our center. The analysis included transplanted units (considered the best choice) & the next best high resolution typed back-up units (reserved but not shipped). Pt racial/ ethnic origins were prospectively obtained by detailed family history & grouped as previously described (Barker J. et al. BBMT 2010).
 Results: The characteristics of 513 units chosen for 136 CBT recipients by pt ancestry are shown (Table 1). Pts had highly diverse origins including 70 (51%) non-Europeans. The 513 units included 270 units infused as the graft (134 doubles & 2 singles) & 243 back-up units (109 pts had 2 back-ups, 25 pts had one & 2 had none). Thus, 4 best units were analyzed in 109 pts (all double unit recipients), 3 best in 25 pts (all doubles), & 1 unit in 2 pts (both singles). The median weight of the 136 pts was 81 kg. Asian pts (median 68 kg) had a lower weight than other groups. The median TNC content of units for the 66 European pts was higher than that for the 70 Non-Europeans (218 vs 196, p = 0.004). Units chosen for Northwestern (NW) Europeans had the highest median TNC content (235) with lower TNC content in units for Southern Europeans (202), Asian (193), African (191) & White Hispanic (189) pts. Units chosen for European pts also had a higher median CD34+ cell content (162) than Non-Europeans (138), p = 0.004. NW Europeans had units with a higher median CD34+ content (198) & the lowest CD34+ content were those for African (124) & Middle Eastern pts (124). When patient weight was considered, median TNC/kg dose per unit was similar in European and Non-European pts (2.7 vs 2.6, p = NS). Units for NW Europeans had the highest median TNC dose (3.0) whereas those for African pts had the lowest TNC dose (2.4). Units for Europeans had a higher median CD34+ dose (2.0) than Non-Europeans (1.7) although this difference was not significant (p = 0.15). Additionally, similar to TNC dose, median CD34+ dose was highest in units for NW European pts (2.2) & lowest in units chosen for African pts (1.5). 89% of chosen units were 4/6 HLA-matched with no differences between Europeans & non-Europeans. Furthermore, the median 8 allele HLA-match was 5/8 (range 2-8/8) with no overall differences between units for Europeans and Non-Europeans (p = NS).
 When only transplanted units were analyzed (Table 2), the median TNC & CD34+ contents were significantly lower in non-Europeans than Europeans (238 vs 216, p = 0.01 & 184 vs 160, p = 0.016). Overall, however, units received by Europeans vs non-European pts had similar TNC & CD34+ doses (p = NS). However, differences in the CD34+ content combined with differences in pt weights resulted in disparities in CD34+ doses by ancestry sub-group. NW Europeans (high weight, high CD34+ content) received the best CD34+ doses; lower CD34+ content in Asian pts was compensated for by their lower weight. African pts (high weight, low CD34+ content) received the lowest CD34+ doses. The median 8 allele HLA-match for all was 5/8 (range 3-8/8) with the exception of African pts [median 4/8 (range 3-7/8)]. Moreover, while 108 (40%) of transplanted units were 3-4/8 HLA-matched overall, there were marked differences between pt sub-groups with only 23% of units for NW Europeans being 3-4/8 vs 42% for southern Europeans, 46% for white Hispanics & 53% for Africans.
 Conclusions: While CB significantly extends transplant access to racial & ethnic minorities, differences in cellular content translates to many minority pts receiving lower dosed units. There are also marked racial/ ethnic differences in HLA-match grade with African pts the most likely to receive highly mismatched units. This data supports ongoing funding of public CB banks to further increase the inventory of high dosed & better matched units for all but especially racial & ethnic minority pts.

 Shah: Janssen: Research Funding; Amgen: Research Funding. Kernan:National Cancer Institute: Research Funding.


This paper overviews the most common malicious software types. The motivationof writing this paper was a real wordcase studythat had to be investigated. Acomputer was suspected to have had an unwanted remote desktop connection attack. This paper presents how to investigatethe event log artifacts. For the unfortunate case when such an attack is proved to have happened, the second part of the article describes a method that allows the system administrator to detect brute force attacks through the remote desktop connection. When such an attack was revealed, the attacker's IP address can be blacklisted.


Today's trend of the market requires innovative thoughts and further development of additive manufacturing processes such as beam melting. Especially with regard to the increasing diversity of different product versions with decreasing batch sizes at the same time the additive manufacturing itself becomes more and more important. In general, the additive manufacturing differs from conventional technologies by its layer wise and additive joining together material to a physical part instead of removing material. Because the trend of beam melting moves from prototype production to rapid manufacturing (production of end products with series characteristics), the identification and management of beam-melted parts can be achieved by using RFID technology. In this paper, feasibility studies for producing smart parts by the direct integration of RFID tags into beam-melted parts underneath the surface are investigated. It can be demonstrated that signals from RFID tags can be transmitted through dense metal material. This individual labeling of beam-melted parts leads to new possibilities, especially with regard to the quality management for rapid manufacturing purposes.


BACKGROUND
Contrast induced nephropathy (CIN) is a common complication seen after primary percutaneous coronary intervention (PCI) which can contribute to increased morbidity and mortality in patients of acute ST elevation myocardial infarction (STEMI). Aim of this study was to validate the TIMI Risk Index (TRI) for the risk stratification of CIN in patients undergone primary PCI.

METHODS
Consecutive patients of STEMI undergone primary PCI at a tertiary care cardiac center were included for this study. Patients in Killip class IV at presentation, patients with history of any PCI and chronic kidney diseases were excluded from this study. TRI was calculated using the formula " " and post-procedure serum creatinine level increase of either 25% or 0.5 mg/dL was taken as CIN.

RESULTS
A total of 507 patients were included in this study out of which 82.2% were males and 17.8% were females. In total 8.7% (44) patients developed CIN. In the receiver operating characteristic (ROC) curve analysis, area under the curve (AUC) for TRI was found to be 0.717, [0.649-0.758] for the prediction of CIN. Sensitive, specificity, positive predictive value and negative predictive value of TRI >22.8 to predict the development of CIN were 59.09%, 76.69%, 19.55% and 95.19% respectively.

CONCLUSIONS
TIMI risk index is and easy to calculate and readily accessible score which has good predictive value to evaluate the risk of CIN in primary PCI setting.


The integration of renewable energy sources (RES), energy storage systems (ESS), and electric mobility into smart grids requires the use of dc-dc back-end power converters for adjusting voltage levels. Although a dc-dc converter applied for RES only operates in unidirectional mode, when applied to ESS or EM, the bidirectional mode is a fundamental requisite for exchanging power with the electrical power grid. In this context, this paper presents an experimental validation of a proposed bidirectional three-level dc-dc converter considering its application for smart grids. Traditionally, the dc-dc power converters of such applications are two-level converters. However, by employing a three-level topology, it is possible to improve the quality of the variables controlled by the power converter. Moreover, since the proposed dc-dc converter is controlled to produce a controlled current, the proposed current control and modulation strategies are introduced and described. A complete analysis of the operation principle of the proposed bidirectional three-level dc-dc power converter is presented, supported by experimental validation, employing a laboratory prototype.


The ridesharing problem is to share personal vehicles by individuals (participants) with similar itineraries. A trip in the ridesharing problem is a participant and his/her itinerary. To realize a trip is to deliver the participant to his/her destination by a vehicle satisfying the itinerary requirement. In this thesis, we focus on two optimization goals: minimize the number of vehicles and minimize the total travel distance of vehicles to realize all trips. The minimization problems are complex and NP-hard because of many parameters. We simplify the problems by considering only some of the parameters. We prove that some simplified minimization problems are NP-hard while a further simplified variant is polynomial time solvable. These suggest a boundary between the NP-hard and polynomial time solvable cases. We also propose a novel approach for finding a maximum matching in hypergraphs with special properties, extending the well-known maximum matching theorem in graphs to hypergraphs.


BACKGROUND
A ternary system containing horseradish peroxidase (HRP), glucose oxidase, and D-glucose using one- or two-step treatment was evident able to cross-link proteins via dityrosine formation, and thus was assessed for its possible impact on several properties of a protein ingredient caseinate.

RESULTS
HRP, glucose oxidase, and D-glucose were used at 200 U, 6 U, and 0.05 mmol/g protein to treat caseinate by one- and two-step methods, producing two cross-linked caseinates named CLCN-I and CLCN-II, respectively. In response to the conducted cross-linking, both CLCN-I and CLCN-II gained slightly reduced dispersibility at pH 5-10, enlarged hydrodynamic radius (particle size distribution, 266.37 and 258.33 versus 226.67 nm) and negative zeta-potential (-26.60 and - 22.27 versus - 14.30 mV) in dispersions, increased water-binding (3.70 and 3.09 versus 2.68 kg/kg protein), decreased oil-binding (1.75 and 2.74 versus 2.87 kg/kg protein) and emulsifying activity (76.2 and 82.3 versus 94.3 m2 /g protein), increased emulsion stability (84.3% and 82.5% versus 78.6%), and enhanced thermal stability with lower mass loss (58.5% and 59.6% versus 64.3%) or higher decomposition temperatures (331.2°C and 328.7°C versus 327.6°C) upon a heating of 105-450°C. In addition, CLCN-I and CLCN-II had decreased gelling temperatures and shortened gelling times when forming acid-induced gels, and endowed the gels with increased values in four textural indices and finer micro-structure. Moreover, CLCN-I with higher cross-linking extent showed much property change than CLCN-II.

CONCLUSION
This ternary system could be used in caseinate cross-linking to improve these properties like aggregation, emulsification, gelation, and thermal stability. This article is protected by copyright. All rights reserved.


[Objective]To investigate the cognitive status of occupational exposure to blood-borne pathogens among medical workers,analyze the influencing factors,and provide the basis for improving the protective consciousness of occupational exposure to blood-borne pathogens among medical workers,and carrying out the training of protection knowledge in future.[Methods]300 medical workers in a hospital of Changchun City were investigated by the questionnaire survey. The results were analyzed by ANOVA and t test to explore the influencing factors of occupational exposure. [Results]288 of 300 questionnaires were effective,with the effective rate of 96%. The cognitive level of occupational exposure to blood-borne pathogens among medical workers was not good,and the average scores were only 56.8. The awareness rates of concept of standard prevention,definition of occupational blood-borne exposure,proper use of protective equipment,and treatment after occupational exposure were not satisfactory,all of those were lower than 60%. The main factors influencing the cognitive level occupational exposure included occupation,education level,department and training status,and the differences were significant(P0.05). However,there were no significant differences in scores among different sex,length of service,professional title groups(P 0.05).[Conclusion]It is important to take the targeted training according to the weak links and influencing factors of occupational exposure to blood-borne pathogens among medical workers,and improve their protective level of occupational exposure,to ensure the safety of medical workers.


The characteristics of jobbing work are analyzed, and a systematic structure for design automation in jobbing work circumstance is present. Based on product module library and frame-structured design knowledge library, new product's scheme pattern configuration and parameters' calculation proceed to fulfill automated design process. Then, making use of the results of primary design, the optimized design satisfying customer requests is presented by validating and optimizing the product scheme pattern. At last, a demonstration of an industrial metal forming machine is illustrated.


The maximum, minimum, and mean values for six trace elements in four soil horizons are reported for 14 profiles of red-brown earths from South Australia, and the pattern of variation and distribution of these elements discussed. The elements studied could be arranged in a series of decreasing mobility in the soil, the order being cobalt > copper > gallium > vanadium > molybdenum > manganese. The most mobile elements had greater variations within profiles and, except for manganese, greater variations between profiles. Gallium, vanadium, and molybdenum contents were correlated with the amount of clay present in all surface soils, as well as in individual profiles, whereas cobalt and copper contents were correlated with clay only in individual profiles.


Adjacent Segment Diseases Following Expansive Cervical Laminoplasty: A Report of Five Cases
Expansive laminoplasty has become the gold standard for surgical treatment of cervical multilevel compressive myelopathy. The procedure preserves the motion segment, and it has been believed hitherto that adjacent segment disease would not occur following the procedure. We report the adjacent segment disease following expansive laminoplasty for compressive cervical myelopathy and postulate on the possible pathophysiologic mechanism of the disease.


The research activities at Sapienza University of Rome, with emphasis on leaky waves and periodic structures for antenna applications, are presented. Moreover, a description is given of a doctoral Course (now at the third edition) given in the framework of the European School of Antennas (ESoA)


Boron carbide undergoes an amorphization transition under high-velocity impacts, causing it to suffer a catastrophic loss in strength. The failure mechanism is not clear and this limits the ways to improve its resistance to impact. To help uncover the failure mechanism, we used ab initio methods to carry out large-scale uniaxial compression simulations on two polytypes of stoichiometric boron carbide (B{sub 4}C), B{sub 11}C-CBC, and B{sub 12}-CCC, where B{sub 11}C or B{sub 12} is the 12-atom icosahedron and CBC or CCC is the three-atom chain. The simulations were performed on large supercells of 180 atoms. Our results indicate that the B{sub 11}C-CBC (B{sub 12}-CCC) polytype becomes amorphous at a uniaxial strain s = 0.23 (0.22) and with a maximum stress of 168 (151) GPa. In both cases, the amorphous state is the consequence of structural collapse associated with the bending of the three-atom chain. Careful analysis of the structures after amorphization shows that the B{sub 11}C and B{sub 12} icosahedra are highly distorted but still identifiable. Calculations of the elastic coefficients (C{sub ij}) at different uniaxial strains indicate that both polytypes may collapse under a much smaller shear strain (stress) than the uniaxial strain (stress). On the other hand, separatemore » simulations of both models under hydrostatic compression up to a pressure of 180 GPa show no signs of amorphization, in agreement with experimental observation. The amorphized nature of both models is confirmed by detailed analysis of the evolution of the radial pair distribution function, total density of states, and distribution of effective charges on atoms. The electronic structure and bonding of the boron carbide structures before and after amorphization are calculated to further elucidate the mechanism of amorphization and to help form the proper rationalization of experimental observations.« less


Medical education has traditionally focused on clinical knowledge and skills. However, in recent years, medical humanities education has gained recognition as an essential component of medical training to improve medical students' understanding of medicine's social, cultural, and ethical aspects. With the advent of big data and artificial intelligence (AI), new opportunities have emerged to enhance the effectiveness of medical education. Thus, we propose a novel teaching model for medical humanities education that leverages AI and digital human technology to provide an interactive and engaging learning experience for medical students. In the context of educational practice, the primary purpose of this study is to build a digital simulator and virtual simulation experiment system based on big data and to explore the possibility of its application in the actual teaching process and the practical application results. In practice, a series of clinical teaching cases based on organ systems have been designed and applied to actual medical teaching through this technology. These teaching formats extend the depth and scope of medical teaching, enhance learning interest, and effectively achieve teaching objectives.


I sometimes ponder on the practical effect of the many words written on 'public health'. And then I wonder, perhaps uncharitably, how many are merely a re-hash of what has already been said. So when a new book had not one, but four, concepts in the title, I was tempted to think that there might be something new, perhaps at the intersection of the four. Or was it another re-working of current knowledge? We already know a lot about the rise of inequality over the past three decades, and about 'complexity science' and its applications to health care, public policy, public health and health disparities. This edited compendium serves as a capstone for the work of the multidisciplinary research programme of the Network on Inequality, Complexity and Health (NICH), originating at the turn of this decade at the University of Michigan. The members, all North American, came together in 2010 to bring complexity thinking into public health. They hoped it would permit them to think differently about recurring problems, and to propose new responses. It's well known now, as it was then, that concrete thinkers like to solve by direct means the types of problems in the authors' sights. People are hungry? Provide hot meals while they find a job. Too many obese citizens in a neighbourhood? Encourage them to cut calories and raise exercise levels. Lots of crime? Crack down on the gangs, drug-runners and even the petty criminals; 'three strikes and they're in gaol'. The economy's stagnant? Cut taxes for companies and watch the magical trickledown. If only things were that simple. When issues which look mono-dimensional have resisted easy answers, something different is needed. That's where the NICH came in. As part of a self-assigned mandate, they dug deep into complexity science to figure out new ways to address such 'wicked' problems. They had noticed something profound—most research is cross-sectional, focusing on a single aspect of the problem: a survey, for instance, or a trial. This ignores the ubiquitous properties of systems and communities in which problems are situated. In fact, it treats these as confounders or variables to be controlled, rather than as importantly influential characteristics in their own right—variables which can't be wished away, no matter how tempting that might be. Those characteristics need to be understood and factored into proposed solutions. As any theorist should know, systems and communities are more than the sum of their parts. Participants ('agents') spend time relationship building, networking and making sense of their surroundings. They do not behave in linear ways, and do not respond in a 1:1 fashion to interventions. People comprising systems and communities do more than interact—they selforganize, co-evolve and adapt, dynamically. Participants respond haphazardly to rules from above but also create, or already have perhaps culturally, their own. If perturbed or put under pressure, they are often resilient—and even impervious to imposed change. Big effects in complex systems and communities can come from seemingly small changes (e.g. having women control household resources in traditional, patriarchal societies), and disconcertingly small effects can result from large changes (restructuring health ministries or entire health systems, for example). In short, in complex structures, unpredictable things materialize. Things which have never happened before, happen often. There is always uncertainty and unknowability.


The letter by Spentzas (1) presents several interesting issues regarding severity of illness scores and their uses. Spentzas (1) comments that Pediatric Risk of Mortality (PRISM) "carries issues from the past structure of the PICU." Actually, the current series of investigations are designed to not only meet the evolutionary changes of the PICU but also stimulate future PICU assessments to keep up with the new focus of pediatric critical care and the prevention of morbidity and mortality. First, the National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network developed a measure of morbidity, the Functional Status Score, that is suitable for use in large-scale pediatric such as those required for quality studies (2). Second, the CPCCRN revised the time period for collecting the PRISM score to better separate the assessment of severity of illness (physiological instability) from the outcome (3). Third, the CPCCRN will construct predictors of both morbidity and mortality. This prospective dataset of over 10,000 patients is nearing completion.


A unified description of the tensile flow curve of metals has been presented by assigning a new role to the internal structure variable which is a fundamental variable in the random barrier theory. This description comprising intergranular hardening has provided satisfactory agreement with each experimental curve for stainless steel, nickel-chrome steel, brass and aluminum alloy with a wide range of strain. The various strain hardening behaviors can be systematically expressed with this formula by introducing the variations of the internal structure variable depending on the deformations.


Immunohistochemistry (IHC) has become an essential part of diagnosis and clinical research in lymphomas. There is considerable heterogeneity, however, in IHC findings regarding expression rate and positivity cut‐offs, which creates a degree of uncertainty that has prevented its incorporation for prognostic purposes. The purpose of the present study was to assess intra‐ and interobserver agreement in scoring bcl‐2 expression on IHC. The study materials were 81 diffuse large B‐cell lymphomas. Slides were processed in the same laboratory, and were analyzed independently and in a blinded manner by four pathologists twice, at least 1 month apart. The positivity rates ranged from 31% to 41% in the first evaluation, and from 30% to 43% in the second evaluation. The two analyses by the same pathologist gave concordant results in 88–93% of cases (κ = 0.71–0.83). Complete agreement among all observers varied from 72% to 79%. The experience of the observer did not influence intra‐observer concordance. Cooperative analysis of discordant slides led to consensus in all cases. The variation observed in scoring bcl‐2 expression is acceptable for use in lymphoma diagnosis and classification. The use of IHC stratification, however, for clinical decisions regarding treatment will require standardization and centralized consensus review, and must await the results of ongoing prospective trials.


We report here the results about the sulphur concentration in ancient stones and its removal after the application of UV laser action. A portable apparatus for energy-dispersive X-ray fluorescence (EDXRF) was utilised to measure the sulphur concentration before and after laser cleansing. After laser application the sulphur concentration decrased to 1.2% w/w whilst the initial value was 2.8% w/w. The laser energy density was about 1 J/cm2 and the efficient shot number was approximately 30 with a rate of 1Hz.


The earth stress distribution and influenced factors in Dina gas field in Xinjiang are analyzed.The parameters required for earth stress calculation are determined,such as the rock mechanics and the inherent rock strength using well log data and available results.Using well log data to analyze earth stress is not only to quickly get the stress profile spreading along the depth,but also to save high cost for measurement.Furthermore,the horizontal stress direction of the target zone in the gas field is determined by means of borehole breakout data,drilling-induced fracture and DSI Fast shear azimuth.


We report the detection of a broad dust ring in the X-ray-bright elliptical galaxy NGC 3607, the dominant member of a nearby group of galaxies. The inner radius of the ring is ~1.3 kpc from the nucleus and has a width of ~0.75 kpc. The maximum extinction corresponds to E(B-V)=0.12±0.023. We also confirm the existence of bright Hα nebulosity around the nuclear region of the galaxy, just inside the dust ring. The luminosity in Hα is ~1.5×10 40 ergs/s −1 . The estimated amount of neutral hydrogen in the galaxy is ~4×10 7 solar masses and ionized hydrogen ~1.1×10 5 solar masses. We rule out Hα emission due to cooling flow, heat conduction from hot gas to the cold gas, photoionization by post-Asymptotic Giant Branch (AGB) stars or an active nucleus, and suggest that photoionization by young stars is the most plausible cause. We also suggest that the dust and associated gas are acquired from an interacting neighbor NGC 3608. The results are based on CCD surface photometry of the galaxy carried out using the broad-band filters V and R and a narrow-band filter appropriate for the red-shifted Hα + [N II] emission.


For most industrial companies to become interested in a new technology, the answer to whether the technology has the potential to improve their businessmust be positive. The next question that needs to be answered is how the new technology would improve their business. Obviously, if the processing became cheaper and resulted in the same product, that would raise industrial interest. This might be possible if subsequent processes were made more efficient or faster, as in the case of dehydration of food. The same would apply if the new process reduced the loss of valuable materials; or in the case of harvesting ingredients from plant cells, if the yield increased; or in the preservation of foods, if the new process increased shelf life. Often, however, new technologies are not cheaper and although they may use the same raw materials and ingredients, they are unlikely to produce exactly the same product. New preservation technologies are investigated because of their expected potential to inactivate microorganisms with little harm to the product. New methods regrettably tend to require investments. For the food industry, it is important to know what the improvements would be in terms of quality as perceived by customers. Only if there is at least a fair chance that consumers buy the improved productwill industry consider investing in a new technology. That being the case, several other aspects become important, including product safety, regulatory acceptance, occupational safety, investment costs, and energy costs, to name a few.


Experiments and analysis were used to determine the number of resolvable cycles across an alphanumeric character required for readability. This has serious implications for the resolution needed for a surveillance camera to present a "readable" image to a human. Fourier analysis was used to predict the number of cycles required for readability. Using two-dimensional Fourier transforms, the set of 26 English letters and 10 Arabic numerals was analyzed and classified. This theory is supported by empirical data based on user identification of random English letters and Arabic numerals. The results strongly indicate that accurate readability (defined as 90% correctness or better) can be accomplished with approximately 2.8 cycles across a block letter. This appears to suggest a lower resolution requirement than that generally accepted for unknown target identification. The reason is the limited data set of only 36 alphanumeric characters, of which the observer possesses a priori knowledge. Moreover, the ability to read an alphanumeric is a steep function of the resolution between 2 and 3 cycles per character height. The probability of correct "Reading" can be expressed similarly to that of Detection, Recognition and Identification by using a postscript such as "Read90".


The invention relates to an instrument and method for rapidly detecting the polarity of a temperature-measuring thermal coupler and belongs to the technical field of detecting. The instrument comprises a thermal coupler socket, an access switching relay, a heating power supply, an SOC (ADUC834), a photoelectric coupler, a relay driving audion, a polarity indicating light-emitting tube, a sound alarming device, and a working power supply. The thermal coupler is connected with the access switching relay through the thermal coupler socket. The access switching relay is connected with the heating power supply. The access switching relay is connected with the SOC (ADUC834) which is connected with the photoelectric coupler which is connected with the relay driving audion which is connected with the access switching relay. The SOC (ADUC834) is connected with the polarity indicating light-emitting tube and connected with the sound alarming device. The instrument and method for rapidly detecting the polarity of the temperature-measuring thermal coupler has the advantages that the polarity of the thermal coupler product can be rapidly detected to judge whether the thermal coupler product is qualified or not; wasted products are prevented from flowing into the smelting and temperature measuring process and the efficiency of smelting production is improved.


This article demonstrates a technique for diagnosis of fault location on overhead transmission lines for single line to ground fault. The proposed method is based on discrete wavelet transform (DWT) and radial basis function neural network (RBFNN). A number of features have been extracted from faulty signal using DWT and are used for training of RBFNN for fault detection. It has been found that fault locator based on discrete wavelet transform and RBFNN neural network can accurately locate the fault with an average accuracy 2.31%. From the result it can be concluded that the proposed method for fault location estimation for a single line to ground fault (LG fault) is capable of giving results with acceptable accuracy.


In this paper, a nonconvex nonsmooth multiobjective programming problem is
 considered and two its higher-order duals are defined. Further, several
 duality results are established between the considered nonsmooth vector
 optimization problem and its dual models under assumptions that the involved
 functions are higher-order (??)-type I functions.


Music braille is made up of more systematic and various symbols compared with text braille. Therefore, the translation of braille music requires extensive knowledge of the music and the braille symbols. Because currently the computer program for the text braille has already developed, we don't need any help from the braille translator. However, the translation of music braille is hard without the help of a professional music braille translator, because the translation computer program is not perfect. The current situation is that the music braille translator reads the music score and translates it into the braille himself. In this paper, we designed and implemented the "Braille Music Converter", you can implement a person does not understand the braille translation into music braille well. It includes translation into text braille for the lyrics processing and rest, octave, key signature, time signature, tie, slur, repeat mark was confirmed that the successful conversion to the actual music score.


The relevance of the research topic is that the problem of reliable protection of components and parts from emerging overloads with the help of safety couplings is currently not solved. The problem of research - the definition of a rational layout of the drive. The purpose of the work is to establish a pattern of distribution and change of load in the drive of the machine containing a safety clutch. The method of research is to study the effect of increase rate of the overload on the working body of the machine and its distribution along the kinematic chain of the drive on the level of protection of the safety clutch. It is established that the safety clutch is not able to protect against overload components and parts of the drive, located between the working body and the clutch, if the propagation time of the shock wave is greater than the period of time during which there is an increase in overload on the working body from zero to the maximum value. Based on the study of the load distribution in the drive with a safety clutch when overload occurs on the working body of the machine, the conditions for the performance and failure of the safety clutch to protect the various parts of the drive are found.The relevance of the research topic is that the problem of reliable protection of components and parts from emerging overloads with the help of safety couplings is currently not solved. The problem of research - the definition of a rational layout of the drive. The purpose of the work is to establish a pattern of distribution and change of load in the drive of the machine containing a safety clutch. The method of research is to study the effect of increase rate of the overload on the working body of the machine and its distribution along the kinematic chain of the drive on the level of protection of the safety clutch. It is established that the safety clutch is not able to protect against overload components and parts of the drive, located between the working body and the clutch, if the propagation time of the shock wave is greater than the period of time during which there is an increase in overload on the working body from zero to the maximum value. Based on the study of the load distribution in the dri...


Brooches finger rings gemstones, amulets and cameos bracelets helmets shields and armour weapons and other military equipment iron tools bronze baldric- and belt-fittings votive objects and an amulet in gold votive objects in silver votive objects in bronze miscellaneous objects in bronze lead water pipes lead roundels lead sheets (except defixiones) miscellaneous lead objects stone roundels pottery roundels miscellaneous objects in bone, horn or ivory.


This chapter utilises data from previous research studies to investigate the extent to which resilient techniques are being employed in the repair of flood-damaged property in England and Wales. It discusses the wider implications of the effect of flooding on property values and seeks to offer some conclusions regarding the long-term benefits derived from adopting flood-resilient reinstatement techniques and methods.