MTJ-based cache memory is expected to reduce processor power significantly. However, write energy increases rapidly for high speed operation and considered not suited for lower level cache memory. In this work, we have developed L2 and L3 cache memory based on thermal stability factor engineered pMTJ with 2T-2MTJ and 1T-1MTJ memory cell and novel error handling scheme. These techniques reduce 75% energy with 2% performance overhead compared to SRAM-based l2 and L3 cache memory.


ABSTRACT This paper proposes a dynamic output feedback robust model predictive control for system with polytopic model uncertainty. Earlier researches on this topic utilise iterative methods to solve the non-convex optimisation problem which are computationally demanding. In order to reduce the computational burden, we explore a new approach in this paper, where, by utilising some proper matrix transformations, a computationally more efficient but conservative convex optimisation problem is formulated which can be solved in terms of linear matrix inequalities. Furthermore, we try to reduce the conservativeness by introducing a nonsingular matrix as a degree of freedom. The recursive feasibility and the convergence of the augmented state to the equilibrium point are guaranteed. The effectiveness of the proposed approach is illustrated by two numerical examples.


The partial fiber breaking in the warp yarn of three-dimensional (3D) woven fabrics needs to be urgently reduced considering the large shedding displacement and repeated yarn frictions in the fabricating process. A kinematical model of the heald frame was established in order to analyze the impact and wear of the warp yarn in the shedding process of 3D weaving. The variation tendency of the friction force between the yarn and heddle eye was obtained and the variable acceleration trajectory of the heald frame based on minimizing the friction and impact load on the yarn was derived. The experimental results showed that the fiber breakage rate in one warp yarn using the derived curve trajectory reduced drastically. The research results are beneficial to the theoretical design of the shedding system of weaving machines for 3D woven fabric.


Abstract: Primary cultures of meningeal cells from embryonic rat cerebra secrete neurite growth‐inducing components into serum‐free culture medium. This conditioned medium (CM) was analyzed by FPLC and immunochemical and enzymatic treatments and tested for neurite promoting activity (NPA) in a quantitative bioassay using hippocampal neurons from embryonic rat. By immunoprecipitation or specific adsorption we identified laminin (LN)‐proteoglycan complexes and fibronectin (FN), respectively, as the major neurite promoting components within meningeal cell CM. The LN‐proteoglycan complexes and their NPA were sensitive to chondroitinase (chondroitin ABC lyase, EC 184.108.40.206) and to a smaller extent to heparitinase (heparitin sulfate lyase, EC 220.127.116.11). Minor fractions of the total NPA in CM correlated with free LN and a putative but not yet characterized FN‐proteoglycan complex.


The core of the navigation program for the Oak Ridge CESAR (Center for Engineering Systems Advanced Research) robots is a production system developed on the expert system shell CLIPS, which runs on an NCUBE hypercube aboard the robot. The production system can call on C-compiled navigation procedures. The production rules can read the sensor data and address the robot's effectors. This architecture was found to be efficient and flexible when used for the development and testing of the navigation algorithms. However, to process unexpected emergencies intelligently, it was necessary to control the production system through externally generated asynchronous data. This led to the design of an asynchronous production system, APS, which is being developed on the robot. Some of the navigation algorithms developed and tested at CESAR are reviewed, and the need for APS, and how it is being integrated into the robot architecture, are discussed.<<ETX>>


Dengue virus is a member of flavivirus group. Diseases caused by flaviviruses have been a scourge of mankind for long history of human kind; with yellow fever at the top, followed by dengue fever, Japanese encephalitis (JE) and Russian spring-summerencephalitis (RSSE). Due to the dvevelopment of a safe and efficacious live-attenuated vaccine against yellow fever as a first laboratory-designed virus vaccine, this disease is no longer a threat in countries where adequate vaccination is practiced. Similarly, safe and efficacious inactivated vaccines against JE and tick-borne encephalitis (TBE) have also been developed, resulting in dramatical reduction in the disease incidences. In spite of these successes, the development of vaccines against other pathogenic flaviviruses, such as dengue fever and RSSE have not been successful. Control of dengue virus became rather urgent because of the emergence of newsyndrome, dengue hemorrhagic fever (DHF), which causes high mortality amonginfants. The present review attempts to summarize the characteristics of dengue fever and DHF, commonfeatures of flavivirus infections as the basis vaccine development and recent advances and problems encountered in dengue vaccine research. 1. Diseases Caused by Flaviviruses. Diseases caused by flaviviruses have been recognized as severe public health problems in various parts of the world for centuries. Yellow fever was first identified in 1667 in Barbados and continued to be a major threat to public health in the Americas throughout the nineteenth and the early part of the twentieth century. In Africa, yellow fever has still been causing periodic epidemics with the most recent occurring in Gambia and Ghana in 1978. Dengue fever has been recognized since 1780 and has since been described in every continent including Europe and Americas. Dengue fever continues to be a serious threat with outbreaks occurring almost annually in south-east Asia, causing several hundred deaths, particularly of young children. A severe, occasionally fatal form of the disease was reconized in Asia in 1957. This new type of dengue infection, called DHF, has since been recognized in Caribbean during the 1970's, and in 1981, a large outbreak occurred in Cuba. There is a hypothesis that DHF has an immunopathological basis and occurrs in individuals previously sensitized by infection with a heterologous dengue serotype1'. JE became a serious public problem in the mid 1930 in Japan and recently finding further dissemination among south and south-east Asian countries like India and Thailand.


In this paper, a patch antenna with a slot and a tuning stub, or called a modified E-shaped patch (MESP), has been studied. Simulation has shown that the tuning stub has introduced a new resonant frequency, resulting in a bandwidth of 380 MHz, or 6.8% relative to the central frequency of 5.58 GHz. The experimental result shows 400 MHz, or 7.2%. While the bandwidth of a common rectangular patch of the same size on the same substrate, which is 220 MHz, or 3.96%, by simulation, and 254 MHz, or 4.6% by experiment.


Abstract Flumetsulam (N-[2,6-difluorophenyl]-5-methyl(1,2,4)-triazolo[1,5-a]pyrimidine-2-sulfonamide) was metabolized by similar hydroxylation and glucose conjugation pathways in tolerant corn, wheat, and barley seedlings. Two primary monohydroxylated metabolites, N-[2,6-difluoro-4-hydroxyphenyl]-5-methyl(1,2,4)-triazolo[1,5-a]pyrimidine-2-sulfonamide (M 1) and N-[2,6-difluorophenyl]-5-hydroxymethyl(1,2,4)-triazolo[1,5-a]pyrimidine-2-sulfonamide (M 2) and a dihydroxylated metabolite N-[2,6-difluoro-4-hydroxyphenyl]-5-hydroxymethyl(1,2,4)-triazolo[1,5-a]pyrimidine-2-sulfonamide (M 3) were isolated and identified by negative FAB/MS and proton NMR spectroscopy. Isolated secondary O-glucosides of metabolites M 1, M 2 and M 3 were tentatively identified by negative FAB/MS and/or β-glucosidase hydrolysis. Microsomal cytochrome P450-dependent monooxygenases responsible for flumetsulam hydroxylation were isolated from naphthalic anhydride- and ethanol-induced shoot tissues of etiolated corn, wheat, and barley seedlings. Enzyme activity required NADPH and molecular oxygen and was inhibited by carbon monoxide in the dark and by other cytochrome P450 inhibitors. Inhibition by carbon monoxide was reversed by light. Enzyme kinetic and inhibition studies suggested that different cytochrome P450 forms may be involved in flumetsulam hydroxylation at the 4-position on the 2,6-difluorophenyl ring (M 1) and the methyl group on the substituted pyrimidine moiety (M 2).


This research deals with the frameworks of political analysis of the issue of the demonstrations in the news bulletins of the Iraqi satellite channels represented by Al-Iraqiya, Dijla and Al-Atija channels, which were selected according to an exploratory study conducted by him. Iraqi Ministry of Foreign Affairs. The researcher concluded to a sample of the public that these channels are the most followed, and the orientations of these three channels differ, where Al-Iraqiya TV represents the official view of the state, while Dijla TV represents a partisan viewpoint opposing the government's policy. While the channel represents the Islamic line and then one of the channels of the Union of Islamic Radios and Channels in Iraq, the research problem was represented in the main question "What are the frameworks for political analysis of the issue of demonstrations in Iraq. Iraqi satellite news releases? This research is descriptive research, and the researcher used the survey method and the content analysis tool, where he analyzed the eight pm news bulletins for the chosen period and mentioned in the time domain of the research, so the analysis was done in a comprehensive inventory method: (an interview represented by (55) interviews on the trend channel, and (50) interviews on Al-Iraqiya channel, and (40) interviews. Interviews on Dijla channel, the researcher reached a number of results, the most important of which are: 1. The frameworks for the proposed solutions to the issue of the demonstrations came first within the frameworks mentioned in the political analysis, due to the interest of political analysts in resolving the issue before it is too late and the situation recedes. Al-Iraqiya channel topped this framework and tried to find solutions and avoid a collision between the government and the demonstrators and sought calm.2. The warning framework came in second place among the frameworks, and the warning frameworks launched by political analysts varied, including warnings to the government in dealing with the demonstrations and not suppressing them, as presented by the Dijla satellite channel, and from there to the demonstrators. Themselves. . Fear of calm exit, according to what was reported by Al-Ittijah and Al-Iraqiya channel. 3.Dijla channel topped the conflict frameworks that were presented with a political analysis and focused on the Iranian-American conflict inside Iraq and the conflict between the demonstrators and the government, and since the first day of the political demonstrations, Dijla channel adopted its support. To the demonstrators and win the audience in all ways. 4. The political analysis focused on the keywords, and the designations differed from one channel to another. Political analysts in Dijla TV stressed the designation of "militias" and pointed out that there are entities affiliated with Iran that are killing protesters. As for the political analysis in the direction, it confirmed the Joker gangs, which accuse them of working for the United States.5. Political analysts highlighted the active forces with different roles, between negative and positive. Dijla channel described Iran's role as an active force with a negative role and a channel that describes the United States as a subversive role in Iraq. As for the religious authority in Najaf as an active force, everyone agreed. Political analysts talk about the paternalistic role it plays in solving the country's problems.


Ten years old female child presented with clumsy gait, drooling of saliva, difficulty in speech, and behavioral changes. Patient also had poor performance in school. Ocular examination showed positive KayserFleischer ring (K.F.ring) with torch, which was confirmed by slit lamp examination of cornea. Her biochemical and radiological parameters supported the diagnosis of Wilson Disease. Medical line of treatment was started and regular follow up advised to evaluate the outcome.


The aim of this paper is to show the influence of contemporary globalization and its elements on the performance of banks. Key factors of globalization, such as deregulation and financial liberalization led to growth in economies around the world, including countries in transition. In such an environment, a temporary economic growth is a result of the inflow of foreign capital, which attracts investors, with the aim of rapidly increasing capital. In such an environment, with the support of liberalization and deregulation, banks seeking a greater profit, grant more loans. The minimization of risk is a key factor that has feedback. Inadequate control lending escalated the collapse of the finance market, which inevitably spilled over to real sector. This mechanism of communicating vessels destroys itself. In regard to the settlement of the new situation, it is necessary to better supervision and monitoring of financial institutions, especially banks. Keywords—Banks, capital adequacy, liquidity, economic crisis, financial performance, globalization. The beginning of the XXI century has definitely confirmed the affirmation of a new paradigm in modern banking, determined the development of the globalization process. Uncontrolled power of global markets and unrestricted mobility of transnational companies are the most important force in the global economy do not tolerate territorial restrictions and cannot be subject to effective management, which the national oriented states are becoming "virtual" or less relevant to the implementation and organization of economic activity [1]. There is no universally accepted definition of globalization. There are a lot of definitions which more or less used, which more or less made concrete, but there is no generalized view of the concept of globalization. The reason for this is the complexity of the concept and different ways of observing this phenomenon. From an economic point of view, the process took on three dimensions: the globalization of modern financial markets, globalization of banking products and services and the globalization of modern banking [2]. At the present time, exist a big changes in the world. The world stands at the center of the national economy and the national state, so it almost from scratch. To express all these major changes and developments, we come to the concept of globalization, the force that creates a new world; a new dictate terms, and affects all of humanity. Changes in the global environment have led to increased freedom by tightening global banking, but also changed the conditions for achieving competitiveness. Expressed skepticism about the possibility of monitoring global economic trends by nation-states, is transferred to the sphere of international management structures of financial sector of developing countries [3]. We are witnesses of growing interdependence between countries around the world, while activities Globalization and its Impact on Contemporary Banking in Transition Countries RANKA MITROVIC, MARIJANA LJUBIC Faculty of Business Studies Megatrend University Goce Delceva 8, Belgrade SERBIA email@example.com email@example.com www.megatrend.edu.rs/fps


To create an effective network and the successful implementation of logistics activities necessary to conduct a careful design of building logistics systems in the industry. Strategic logistics, based on long-term goals of the company, can significantly change the whole system of the enterprise organization. Any logistic transformation involving significant costs, and therefore requires the implementation of a consistent and deployed in space and time of a program of activities that are both complex of socio-economic, organizational, technical, informational, legal, personnel and other prerequisites for the creation of full-fledged logistics software existing structures. As a relatively new tool management, logistics is a synthesis of many techniques and principles such traditional areas as marketing, production, finance, transportation. Using logistic concepts allows for tight integration of production, logistics, transport and transfer of information on the movement of goods in a single system.


Harmonious society of Socialism possesses rich connotation. It will take quite hard efforts to build up harmonious society from every aspect of politics, economics, law and society. The author deems that respecting and safeguarding human rights is the "Archimedes Fulcrum" of building up harmonious society. The article respectively proves this viewpoint from the following three accounts: respecting and safeguarding human rights is the cornerstone of building up harmonious society; is the important theme of building up harmonious society; is the basic value orientation of building up harmonious society.


Reaction of the Sb(III) dimer [Me2NSb(μ-NCy)]2 with LiNH2 (1 ∶ 2 equivalents, respectively) gives [{Sb(μ-NCy)}2N]3(Li·THF)3(LiNNH)·0.25(dioxane) 4, in which four Li+ cations are coordinated within the trimeric cavity of the macrocyclic trianion [{Sb(μ-NCy)}2N]33−.


For the many categories of EFL teachers throughout the world, this book examines the main principles which concern them. By drawing upon their experience the authors have indicated a modern and practical approach.


The major pathway of bioactivation of procarcinogenic heterocyclic aromatic amines (HCAs) is cytochrome P450 1A2 (CYP1A2)–catalyzed N‐hydroxylation and subsequent esterification by O‐acetyltransferase (O‐AT). We have previously reported that an umu tester strain, Salmonella typhimurium OY1001/1A2, endogenously coexpressing human CYP1A2 and NADPH‐P450 reductase (reductase), is able to detect the genotoxicity of some aromatic amines [Aryal et al., 1999, Mutat Res 442:113–120]. To further enhance the sensitivity of the strain toward HCAs, we developed S. typhimurium OY1002/1A2 by introducing pCW″/1A2:hNPR (a bicistronic construct coexpressing human P450 1A2 and the reductase) and pOA102 (constructed by subcloning the Salmonella O‐AT gene in the pOA101‐expressing umuC″lacZ gene) in S. typhimurium TA1535. In addition, as an O‐AT–deficient strain, we developed the OY1003/1A2 strain by introducing pCW″/1A2:hNPR and pOA101 into O‐AT–deficient S. typhimurium TA1535/1,8‐DNP. Strains OY1001/1A2, OY1002/1A2, and OY1003/1A2 expressed, respectively, about 150, 120, and 140 nmol CYP1A2/l culture (in whole cells), and respective cytosolic preparations acetylated 15, 125, and ≧0 nmol isoniazid/min/mg protein as the O‐AT activities of cytosolic preparations, respectively. We compared the induction of umuC gene expression as a measure of genotoxicity and observed that the OY1002/1A2 strain was more sensitive than OY1001/1A2 strain toward the genotoxicity of 2‐amino‐1,4‐dimethylimidazo[4,5‐f]quinoline (MeIQ), 2‐amino‐3‐methylimidazo[4,5‐f]quinoline (IQ), 2‐amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline (MeIQx), 2‐aminoanthracene, 2‐amino‐6‐methyldipyrido[1,2‐a::3,2′‐d]imidazole, 3‐amino‐1,4‐dimethyl‐5H‐pyrido[4,3‐b]indole, and 3‐amino‐1‐methyl‐5H‐pyrido[4,3‐a]indole. However, the genotoxicity of MeIQ, IQ, and MeIQx was not detected with the OY1003/1A2 strain. These results indicate that the newly developed strain OY1002/1A2 can be employed in detecting potential genotoxic aromatic amines requiring bioactivation by CYP1A2 and O‐acetyltransferase. Environ. Mol. Mutagen. 36:121–126, 2000. © 2000 Wiley‐Liss, Inc.


This paper presented 6 medical records about the early sign,emergency,sequel,Bi-syndrome and depletion syndrome of stroke and analyzed the differentiation,treatment and experience of stroke;it is viewed that differentiating and treating stroke from deficiency of primordial qi is one of the most important aspect,and deserves to be used in clinic.


At first glance, the Congressman from Kentucky and the Congressman from Missouri don't seem to have much in common. The Kentuckian, Henry Clay lived in the beginnings of the industrial age. He struggled to foster compromise among America's competing political and economic interests. The Missourian, Richard Gephardt, lived on the cusp of the information age. Both men were fascinated by trade policy. Henry Clay saw tariffs as a tool for economic development; they could nurture American industry and could fund a national system of roads and bridges. In this way, northern producers could secure the southern and fledgling western market for their manufactures and commodities. National harmony and economic prosperity would be the result. Clay thought that the right approach to trade policy would help Americans achieve a wide range of important policy goals [Eckes, 1995, pp. 19-25]. Congressman Richard Gephardt, in contrast, feared that trade policies thwarted the achievement of other important policy goals such as protecting the environment. He believed "the terms of trade are also an implicit statement of moral values."1 Thus, trade agreements must be designed to make global markets more equitable as well as more efficient. "We must not negotiate away our jobs and our living standard based on outdated theories.. .about trade and international economics." In his view, future trade agreements must be made more comprehensive and include internationally accepted rules covering the envi ronment, human rights, labor rights, and food safety [Gephardt, 2/26/1997, p. 2]. Although the two men had different views of what trade policy should achieve, historians, economists, trade policy analysts, and other observers have described both men as "protectionists." After all, both Gephardt and Clay believed that unencumbered trade was not always in the interest of the


With the rapid development of society,to some extent,the emergence of peasant workers promote so-cial development,it has also impacted on the values,ethics and moralities of traditional society.It is no doubt that intensifying the ethical research and response for the problems of peasant-workers would be of great social reality significance.


Synchrotron radiation is a very important emission process in quasars and AGN, due to its very broad band spectrum (extending over many decades of frequency) and its strong polarisation. It is the dominant process at radio frequencies in relativistic jets seen in radio galaxies and quasars, and in some jets (Chapter 2) this synchrotron emission is observed to extend to optical frequencies. Under unified models of AGN, such optical synchrotron jets are expected to exist in core-dominated quasars (such as those found in the PHFS), and this forms the basis for the modelling in this thesis. A key observation that results from optical synchrotron jets is that the spectral index at optical frequencies is steeper than the average spectral index from the radio to the optical. This indicates that the synchrotron emission is turning over in the optical region – a feature that results from a cutoff or break in the energy distribution of the radiating electrons. This observation is supported by our modelling (see point › below). From the analytical theory of synchrotron emission, discussed in Chapter 3, we found that synchrotron emission from a highly ordered magnetic field will exhibit a strong dependence on the viewing angle. This dependence is of the form L ∝ (sin φ) 2.5 , where φ is the angle between the line of sight and the direction of the magnetic field. This finding is significant because it acts in the opposite sense to Doppler boosting. If plasma is moving with some relativistic bulk velocity in a direction close to the line of sight, then the observed flux will be strongly boosted. The amount of boosting will


Abstract The private gardens designed by Lawrence Halprin responded to evolving social circumstances within the United States after World War II. Along with contemporaries such as Garrett Eckbo, Robert Royston, Douglas Baylis and the more firmly established Thomas Church, Halprin sought to provide outdoor living environments that fulfilled the needs of a new middle-class. Though each of these designers experimented with similar aesthetic devices, such as interpenetrating planes borrowed from Cubism and De Stijl, biomorphic forms associated with surrealism, as well as ubiquitous curves and zig-zags, the program was fundamentally social.


Includes instruction on how to save searches and set automatic alerts in PubMed, Ovid Databases, Web of Science, CINAHL and EMBASE. Create a My NCBI account to saves searches and set up email alerts. You will also be able to store items to a collection and customize PubMed's results page.


Ethology applied to the management of behavioural disorders is naturally based on fundamental ethology.
 The scientific bases are essential to avoid being misled into unfounded and non-validated models.
 In the particular case of dogs, a species which evolved in close proximity to man, has been domesticated
 for a very long time, and has been subject to many selections, the main focus for the ethologist
 should be the study of the interactions between humans and dogs. Research applied to pets should
 therefore lead to a better understanding of their welfare, specific ethological needs, and individual
 coping skills in an environment defined by and for humans. The clinician must use objective ethological
 data to identify the causes of poor welfare and maladaptation, in order to offer owners a rational
 path to solve behavioural problems.


Objective To investigate the IGF-2 imprinting status in tissues of gastric cancerpatients and its relationship with the other clinical / pathological parameters in gastric cancer. Methods IGF-2 imprinting status was determined by PCR and RT-PCR, followed by restrictive endonuclease (Apa I) digestion in 90 patients with gastric adenocarcinoma. The loss of imprinting (LOI) of IGF-2, and its relationship with the other clinicopathologic parameters was studied in a group of prospectively recruited patients. Results LOI was positive in 16 of 33 cases(48.5%) of gastric cancer tissue; 7 of 33(21.2%) in adjacent neighboring mucosa; and 4 of 33(12.1%)) in distant neighboring mucosa. The prevalence of IGF-2 LOI in cancer was significantly higher in patients with positive lymph node metastasis (60.7%) and in cases belonging to advanced stages (TNM: Ⅲ/Ⅳ) (93.7%), as compare to those with negative lymph-nodes (20.0%) (P0.05), and those belonging to early stages (TNM: Ⅰ/Ⅱ) (12.5%)(P0.05), respectively. Conclusions IGF-2 LOI has been confirmed to be associated with the initiation and development of gastric cancer, which was related with clinical staging; pathological staging and prognosis.


This study aimed to validate the prognostic value of baseline whole-body metabolic active tumor and PET/CT) in a large cohort of chemorefractory metastatic colorectal cancer (mCRC) patients treated with multikinase inhibitors (MKI). The secondary objective of this study was to compare WB-MATV and WB-TLG respective prognostic values to commonly used clinical prognostic factors. from investigating The were retrospectively to and a validation WB-MATV and WB-TLG optimal cutoffs for prediction of overall (OS) were determined by and O'Quigley's method. Univariate analyses were performed to assess the prognostic values of WB-MATV and WB-TLG. Multivariate analyses were performed for WB-MATV and WB-TLG along with clinical factors to identify the independent prognostic factors of OS. The prognostic weight for each parameter was obtained from the Cox's model. negative prognostic parameters for OS, with the highest prognostic weight among the well-known clinical prognostic factors (HR: 2.46 and 2.23, respectively, P < 0.001). Baseline WB-MATV and WB-TLG parameters were validated as strong prognosticators of outcome in a large cohort of chemorefractory mCRC patients treated with MKI. These parameters were identified as independent prognostic imaging biomarkers with the highest prognostic values among the commonly used clinical factors. These biomarkers should therefore be used to support the optimal therapeutic strategy.


In hyperlordosis of the lumbar spine, the abdominal aorta becomes well palpable and behaves like a pulsating tumor in the lower abdomen. This normal finding often cannot be differentiated from pathologic changes by clinical investigation alone. Sonography offers a simple method, without risk, for the definitive diagnosis of the abdominal aorta.


The objectives of this paper are to quantify the enhancement of the mass transfer performance in NH₃/H₂O absorption and to study the combined effect of nanofluid and surfactants on the absorption characteristic. In order to apply nanofluid to the absorption system, binary nanofluid which means binary mixture with nano-sized particles is tested in this study. The concentration of NH₃ in the base fluid, that of nanoparticles in the nanofluid, and that of surfactants in the nanofluid are considered as the key parameters. The results show that the addition of surfactants enhances the absorption rate up to 4.8 times with 2-Ethyl-1-Hexanol 700 ppm in 18.7% NH₃ solution, and nanofluids increase the absorption rate up to 3.2 times with 0.1 mass fraction of Cu particles. It is also found that the absorption performance enhanced up to 5.3 times in the NH₃/H₂O by the combined surfactant(2-Ethyl-1-Hexanol 700 ppm) and nanoparticles(Cu nanoparticle 0.1 mass fraction). It can be concluded that the addition of surfactants and the application of binary nanofluid enhance significantly the mass transfer performance during the NH₃ bubble absorption process.


The changes of the YBa2Cu3O6.5+δ properties and composition caused by dc and ac treatments at 77 K have been studied. Considerable changes of the cations and oxygen concentrations due to dc effect have been observed for the first time. Elements have been found to migrate both along the sample length according to the electrode polarity and between the sample bulk and the surface. Small impurities such as S, Si, K and Cl have been observed to migrate along the sample length as well. The composition variations are accompanied by changes of magnetic properties and intragrain critical current density. Some aspects of HTSC degradation under these conditions are discussed.


This study observes the literary role of the language of "resurrection" in developing the message of 1 Peter.  The term itself goes mainly unexplained, and must be understood as part of the "retranslation" process in which the author is engaged--a process by which a dominant Roman political ideology is challenged as believers are encouraged to "rewrite" their lives in terms of experiencing the sufferings as a "normal" dimension of Christian existence.


Background: currently, stem cell therapy is increasingly dominated, as part of the new scientific advances, however its use in the oral cavity is insufficient, which is very propitious for biotechnological procedures of regenerative therapy. Objective: to analyze current knowledge about stem cells and their applications in dentistry. Methods: a bibliographic review was made where 47 references obtained from databases such as Hinary, SciELO and Pubmed in Spanish and English were consulted, of which 37 articles fulfilled the research requirements. The historical logical method was used for the introduction and development of the work and the analysis and synthesis method to draw conclusions. Development: stem cells are cells that have the ability to divide themselves and differentiate into various types of specialized cells. The use of stem cells in the dentistry field and in Cuba is not currently recognized, and nevertheless constitutes a promise of regenerative therapy. Conclusions: regenerative cell therapy with stem cells is a new method with great therapeutic potential and proves to be a good alternative for the treatment of alterations in teeth and other oral structures. DeCS: STEMCELLS; CELL- AND TISSUE-BASED THERAPY; REGENERATIVE ENDODONTICS; TOOTH INJURIES; ORAL HEALTH.


Katsumi Ida National Institute for Fusion Science E-mail: firstname.lastname@example.com Professor Kenro Miyamoto, a member of the Nuclear Fusion Editorial Board from 1972 to 1988, passed away on 4 April 2022, at the age of 90. Dr Miyamoto graduated from the Department of Physics at the University of Tokyo in 1955 and spent a few years at the Nippon Kogaku Kogyo company (now Nikon). He studied at the Institute of Optics at the University of Rochester, USA. Under the guidance of E Wolf, he was awarded a PhD degree from the university in 1959. He became an associate professor at the Plasma Research Laboratory, Nagoya University, and then a professor at the same institute from 1979 to 1992. He designed and built the JIPP-1 stellarator and led the JIPP-II project, which boosted fusion research in Japan. Then he moved to the University of Tokyo and built the REPUTE-1 reversed field pinch device, in collaboration with the Department of Atomic Energy, Faculty of Engineering, and devoted himself to education and research. After retirement, he worked as a professor at the Faculty of Engineering, Seikei University, and was engaged in research at the Japan Atomic Energy Research Institute (now National Institutes for Quantum Science and Technology). For the younger generation, he is known as the author of the textbook Plasma Physics for Fusion (Iwanami Shoten Publishers, MIT Press, etc), which is the most comprehensive textbook in this field and is still referred to occasionally. The fusion research community has lost one of its prominent figures. Kenro Miyamoto will be missed for his scientific knowledge and achievements.


A method for finished wire guiding grooved cylinder of synthetic plastics material source in the textile industry for producing a winding machine; finished wire guiding grooved cylinder of synthetic material. a) housed within the casting mold RTV (room temperature vulcanizing) silicone rubber molding cavity; b) filled with 70% aluminum hydroxide catalyzed by injection casting polyurethane resin, in a mold to centrifugation and subsequent catalytic guidance slot die barrel, is provided to cover the wire guiding grooved cylinder insert molding; c) release; D) applying a nickel electro-forming the hard and abrasion-resistant coatings of hard chrome plated coating.


Transcription fromall early adenovirus pro- moters isstimulated bya289aminoacidphosphoprotein en- coded inthepre-early transcription unit EIA.Todetermine if this protein could actonanonviral geneplaced ontheviral chromosome, adenovirus recombinants wereconstructed in which theratpreproinsulin Igene, including its promoter re- gion, wassubstituted inbothorientations forEIA.Preproin- sulin mRNA synthesis fromthese recombinants wasgreatly stimulated after infection ofline 293cells, which constitutively express ElAprotein, compared toHeLacells, whichdonot. Expression ofthepreproinsulin genewasalso greatly stimulat- edwhenHeLacells werecoinfected withtherecombinants and wild-type adenovirus oramutant defective inasecond ElA protein, butmuchless sobycoinfection withamutant defec- tive inthe289aminoacidphosphoprotein. MuchoftheEIA- induced preproinsulin mRNAhada5'endatthesameposition asthepreproinsulin mRNA isolated frominsulinoma cells, but aconsiderable fraction had5'endsmapping heterogeneously within several hundred nucleotides ofthis site. Preproinsulin mRNA wasalsodetected in293cells butnotHeLaorHEK cells after transfection ofaplasmid containing thepreproinsu- lingenewithnoadenovirus sequence. Thisindicates that there isnocis-acting adenovirus sequence required forElAprotein stimulation ofpreproinsulin transcription. Infection ofrat cells withadenovirus didnotinduce detectable mRNA synthe- sisfromtheendogenous preproinsulin Igene. Theseresults demonstrate thattheElAprotein caninduce expression ofa nonviral genewhenitisnewlyintroduced intomammalian cells byviral infection ortransfection, butitdoesnotinduce theendogenous cellular gene.


Chromosomes are exceedingly long topologically-constrained polymers compacted in a cell nucleus. We recently suggested that chromosomes are organized into loops by an active process of loop extrusion. Yet loops remain elusive to direct observations in living cells; detection and characterization of myriads of such loops is a major challenge. The lack of a tractable physical model of a polymer folded into loops limits our ability to interpret experimental data and detect loops. Here, we introduce a new physical model – a polymer folded into a sequence of loops, and solve it analytically. Our model and a simple geometrical argument show how loops affect statistics of contacts in a polymer across different scales, explaining universally observed shapes of the contact probability. Moreover, we reveal that folding into loops reduces the density of topological entanglements, a novel phenomenon we refer as "the dilution of entanglements". Supported by simulations this finding suggests that up to ∼ 1 − 2Mb chromosomes with loops are not topologically constrained, yet become crumpled at larger scales. Our theoretical framework allows inference of loop characteristics, draws a new picture of chromosome organization, and shows how folding into loops affects topological properties of crumpled polymers.


Based on the data of sandstorms and precipitation,a study of sandstorms in the Loess Plateau and the neighboring areas has been made.Through analysis of relationship between mean annual number of sandstorms and mean annual precipitation,an original sandstorm zone and a secondary high-frequency zone of sandstorms have been found.The latter was formed as a result of human activities such as vegetation destruction and waste-land cultivation.The secondary sandstorm zone is 350 km to 500 km away from the original sandstorm zone,reflecting that the sandstorm zone in the Loess Plateau area has been shifted 350 km to 500 km to the southeast,as response to human impacts.Some abrupt change has been found around the belt of mean annual precipitation of 300 mm,where the original sandstorm zone suddenly shifts to the secondary high-frequency zone of sandstorms.Hence,this transition area can be regarded as an abnormally unstable area.


The modular crash cushion is an arrangement of 55-gal tight-head barrels positioned to protect motorists from inadvertently driving into rigid obstacles. A crash cushion should be capable of stopping a moving vehicle over a distance sufficient to allow a relatively low deceleration rate. The modular crash cushion has been subjected to 6 full-scale vehicle crash tests. Three of these tests were headon impacts, 2 were at an impact angle of 30 deg, and 1 was at an impact angle of 20 deg. The photographs and data reported in this paper show that the modular crash cushion was highly effective in stopping vehicles with acceptable levels of deceleration. As a result of these tests, modular crash cushions have been installed at 4 locations in Houston and 2 locations in Dallas; contracts are being let for additional installations in Texas and other states. Since the cushions were installed in Houston, 5 vehicles have collided with them with very minor damage to the vehicles. Only 1 of the 5 drivers received even minor injuries.


A comparative study of Malaysian and Australian managers used the Carson and Bedeian multidimensional career commitment measure and the individualism-collectivism scale developed by Singelis et al . (1995) in a survey to test the hypothesis that career commitment is likely to be higher in individualistic than in collectivistic cultures. Malaysian managers were more collectivistic but also more vertically individualistic than Australian managers, and the two groups differed only in their levels of career resilience commitment and were not significantly different in career identity and career planning commitment. These results may reflect a shift from collectivism towards individualism with Malaysia's economic development, but collectivism may also be adapting to economic development and social change and the findings add weight to recent criticism of accepted conceptualizations of cultures.


Argon, used as pressure medium in high-pressure experiments, crystallizes in a hexagonal close-packed structure when the argon is loaded cryogenically in the diamond anvil cell. The behaviour under pressure reveals elastic properties comparable to that of f.c.c.- argon (f.c.c. = face-centred cubic). The bulk modulus is 6.5 (1.3) GPa. The initially good quality of the individual crystals suffers strongly under pressure increase. Heating the cell to 393 K at 8.5 GPa recreates the crystal structure, accompanied by a pressure decrease of more than 1 GPa.


The luminescent properties of Gd2SiO5 powder crystals doped with Eu3+ were investigated using synchrotron radiation and a VUV laser (157.6 nm) as excitation sources. The excitation spectra in the range of 160–330 nm monitoring the red emission from Eu3+ ions reveal bands corresponding to intraconfigurational 4f–4f transitions of Gd3+ and charge transfer states (CTS) of Eu3+–O2−, as well as interband transitions of the Gd2SiO5 host, indicating an efficient energy transfer process from the host or directly from Gd3+ to Eu3+ ions. The inspection of emission lines from Eu3+ ions suggests that there are three inequivalent sites for Eu3+ in this host. The excitation band around 215 nm and the unique emission features associated with this excitation band were attributed to one of the inequivalent Eu3+ sites, which exhibits an unusually weak coupling with host lattice. The energy levels of Eu3+ in the Gd2SiO5 host were tentatively assigned according to the laser excited emission spectra.


10 This research focuses on damage to coral reefs from three anthropogenic stresses: the dropping of anchors and their chains, 11 human contact, and emission of copper from antifouling paints. Forecasting models are described that quantify degradation in 12 terms of percentage of coral cover damaged/year or increasing levels of water toxicity/year. The models utilize a Monte Carlo sim13 ulation that applies a range of values or a probability distribution to each of the numerous uncertain variables. This model has the 14 flexibility to adapt, and become more accurate, when users input assumptions specific to their diving sites. Given our specific 15 assumptions for a frequently visited site, anchors and their chains forecast a distribution of coral reef cover damage with a mean 16 of 7.11% ± 4.77%, diver contact forecast a distribution of coral reef cover damage with a mean of 0.67% ± 0.38%, and antifouling 17 paint forecast a distribution of copper level increase in the water with a mean of 0.037 ± 0.014 ppb. The results support recommen18 dations for the implementation and sustained use of several specific marine recreation practices. 19 � 2005 Published by Elsevier Ltd. 20 Keywords: Coral reefs; Marine recreation; Tourism; Diver damage; Anchors; Antifouling paint 21


Purpose – This paper sets out to evaluate the potential of financial performance benchmarking as an expenditure control tool for a national pathology service comprising both public and private service providers.Design/methodology/approach – Primary data were provided by direct consultation with a wide range of stakeholders, whose experience and perspectives were sought primarily through informal face‐to‐face interviews. The authors analyse these informant contributions alongside official reports and the published literature on dual public‐private health service provision.Findings – Informants identified potential advantages and pitfalls in comparative pathology benchmarking for expenditure control. They also identified some significant negative implications for health service quality and suggested related compromises. Often misunderstood cost benchmarking issues are clarified in the paper.Research limitations/implications – Several areas of importance for further investigation are suggested.Practical impl...


China exists geographically and conceptually at the centre of an ever-widening series of concentric borderlands. For most of the imperial and modern periods, China's cultural centre rested along the course of the Yellow River. Today, China's relations with the borderlands of the "Inner Periphery" reflect a combination of cultural superiority and deep-seated unease, standing against the context of the policy imperatives of national integration. From Beijing's perspective, the "Outer Periphery," comprising Hong Kong, Macao, and Taiwan, reflects historical influences of imperialism and internationalization that have drawn these mainly Chinese societies into greater integration with the world political economy. In both the Inner and the Outer Peripheries, relations with China proper and the central government are conflicted by differences of expectation about autonomy; by differences in perspectives of place that construct the peripheries alternatively as homelands or as border zones of key strategic importance to China; and by differences in ethnicity, language, and culture that affect dynamics of development and organization. Comparison both within and between the Inner and Outer Peripheries can yield important insights not only into China's relations with these areas -- an issue important in its own right -- but also into China's sense of itself. Such comparisons can reveal the ways in which pursuit of national integration in China remains contingent up on central and local conditions, interests and explanations.


Derksen extends the discussion of brain determination in significant ways. He rightfully challenges my criterion of "Could I do otherwise?" as a way of gauging the force of brain determination, and discussion fruitfully shifts to the negotiated spaces between self and embodiment. Derksen also recharges my use of the term "instrument" by linking it with technology studies. I do, however, find problematic his emphasis on techno-agency as a means of linking brain to cultural life, and conclude with a recommendation for exploring the various discursive communities currently shaping our constructions of the brain.


.- Spiny lobstersPamt li'l"uS 'ma:rginatu,s from the Hawaiian Archipelago have undergone heavy fishing pressure since 1980 and have experienced increases in asymptotic length and decreases in mean length at onset of egg production. Prior to the expansion of the fishery, aBo zyme variation was surveyed, and populations were found to be poly morphic at seven loci. In 1987 we col lected spiny lobsters from two of the previously sampled locations (Necker Island and Maro Reef) to test for sig nificant changes in population struc ture or level of genetic variability. No significant changes through time were found at five of the seven loci. Significant differences were detected at Est3 and EstD; however, frequen cies at esterase loci have been pre viously shown to fluctuate through time. Observed number of allelic classes and observed heterozygosi ties have remained unchanged. The data suggest that no change in the amount of variability has occwTed in spiny lobster since the expansion of the fishery.


Variation of body color was investigated quantitatively among Japanese macaques (Macaca fuscata) and compared with other species of the genus Macaca, using a digital color meter. Color is expressed by three values: lightness, red-green, and yellow-blue. The most prominent variation of body color in Japanese macaques is well defined by geography, and the lightness correlates well with the winter temperature. However, the geographical body color cline can be also explained as cryptic function. On the other hand, groups of the Japanese macaques living in peripheral parts of Japan tend to show the varied body color. This pattern of appearance is similar to those of other morphological characters, such as skull, and it may be related to the genetic drift. The hypothesis that the cryptic coloring is the primary function for the body color in macaques, is supported also by the analysis of body color of other species of macaques, taking ecological settings of their living places into consideration.


Microreactors have become an efficient tool for many enzymatic reactions because the laminar fluid flow within the microchannel enables precise process control, rapid mixing, and short residence time. This paper provides a systematic overview of the application of reaction kinetics and the mathematical modeling of enzymatic processes in microreactors. Rapid heat and mass transfer and a high surface-to-volume ratio are usually the reasons why reactions in microchannels proceed faster and with higher yields and productivity compared to conventional macroreactors. Since there are no radial diffusion limitations, microreactors are also an effective tool for determining the kinetic parameters of enzyme-catalyzed reactions. By eliminating the mass transfer effect on the reaction rate, the kinetics estimated in the microreactor are closer to the intrinsic kinetics of the reaction. In this review, the advantages and disadvantages of using microreactors are highlighted and the potential of their application is discussed. Advances in microreactors result in process intensification and more efficient biocatalytic processes in line with the advantages offered by the application of microreactors, such as (i) higher yields, (ii) a cleaner and improved product profile, (iii) scale-independent synthesis, (iv) increased safety, and (v) the constant quality of the output product through (vi) accelerated process development. Furthermore, microreactors are an excellent tool for kinetic studies under specified mass transfer conditions, enhancing the capabilities of other methods.


Though little known today, David Fordyce was one of the leading figures of the outburst of intellectual activity that culminated in the Scottish Enlightenment. His Elements of Moral Philosophy was one of the most widely circulated texts in moral philosophy in the second half of the eighteenth century. Apart from a very expensive facsimile edition, there has never been a modern edition of The Elements of Moral Philosophy. Moreover, the lectures in A Brief Account have never before been published. The significance of The Elements is evidenced by the fact that it was the principal work in the curriculum in moral philosophy throughout the second half of the eighteenth century. It was also included practically verbatim in the first edition of the Encyclopaedia Britannica.


The Seto Inland Sea Area may be divided into two parts, east and west, by a line connecting Onomichi and the Takanawa Promontry. The eastern part is better fitted for salt-making industry. Formeroly this industry was active at Arai and Matogata, but since the middle of the 17th century, the salt fields in such localities as Ako, Ajino, Sakaide and Muya have made a rapid progress, and at the present time they still keep the representative position in this area. Among these, the development of the Ako salt field has been the most remarkable.Studying the process of the development of the Ako salt field since the 17th century, we can find 6 epochs:(1) Expansion of the salt field on a large scale in 1646-1653.(2) Adjustment of the salt transaction business in 1661-1703.(3) Use of coal for fuel in 1823.(4) Enforcement of the monopnly-system in 1905.(5) Modernization of the salt-making factory in 1938.(6) Reconstruction of the salt field since 1952.The investigation of the procss of the development of the salt-making industry at Ako brings us to a conclusion concerning the regional progress of this line of industry.The chief causes of rhe development of the salt-making industry in the eastern part of the Seto Inland Sea, especially at Ako, are; that the climate is suited to it, that the feudal lords protected it during the Edo Era, that the facilities of communication made it convenient to send salt to the various places in Japan.


This study presents a method to predict a day-ahead solar irradiation curve, under extreme meteorological phenomena (Fohn, north and south winds), existing in the province of San Juan, Argentina. The proposed method is based on an artificial neuronal network (ANN) which is trained with a data set filtered by the environmental variables that characterise the mentioned phenomena. A previously calculated ideal solar irradiation curve is modified from the forecasts generated by the ANN. The proposed methodology merges statistical learning methods and numerical weather prediction (NWP) methods, typically used to improve upon the raw forecast of a NWP model. A reduction of the uncertainty in the power production of photovoltaic plants in San Juan can be achieved with the results of the proposed forecasting method.


This report, undertaken by the World Bank Institute's (WBI) evaluation unit, is a strategic evaluation of WBI's programs for parliamentarians. In this regard, it will examine programs which were exclusively planned for parliamentarians (MPs) and ones in which MPs was not the primary focus, but were still in attendance. The report will also analyze the importance of WBI's work with parliamentarians and examine how effective that approach has been for the programs WBI has implemented over the past five years from 1994 through 1998. This study is primarily arranged according to the central issues which surround programs for parliamentarians. These include: key strategies/best practices and pedagogy; logic of the programs; strategic importance of the programs; and utilization and impacts. In this report, part two briefly analyzes and summarizes WBI's work with parliamentarians and its implications, including its importance to WBI. The evaluation design, methodology, and limitations are summarized in part three. Part four, explores the major findings of this report through interviews with parliamentarians, task managers, and other resource persons. Part five, an assessment of WBI's work with parliamentarians that is greater in depth than part two. Finally, the conclusions and recommendations from this study are listed in part six.


Friedreich's ataxia is still a rarity, and the opportunity to examine the spinal cord in an early stage of the disease does not often present itself. The following case is of interest because it occurred in a boy, aged 11 years, who died of an acute intercurrent disease. He had a younger brother who also had this familial affection. The fact that they were negroes perhaps lends additional interest, for Friedreich's ataxia is probably even more rare in the negro than in the white race. The problem which the disease presents is not so much the distribution of the lesions as the causation and exact nature of the affection. As is well known, the disease process is not confined to the posterior columns; it is more diffused, and is evidently a degeneration with neurogliar proliferation, but the causation is obscure and has given rise to a variety of theories, none


Abstract : In Phase I the effects of cold air (c), water (w), fatigue (f), and exercise (e) on physiological and psychological performance, and the effectiveness of several techniques for the suppression of shivering were investigated in 15 male subjects. Cold exposure was determined to be the most significant factor in reducing performance, causing significant reductions (p < or = 0.05) in skin and rectal temperatures, temperature perceptions, shooting performance, grip strength, and dexterity both alone or when combined with any or all other factors. Cognitive performance, however was highest in the c/w/e/f, control, and c conditions, with the overall scores in the c/w, c/w/f and c/w/e conditions significantly lower than control and c/w/e/f. Shivering gradually increased throughout exposure in cold conditions but was delayed in conditions which included exercise. Rectal temperatures increased during exercise, but later fell to the same level as in the non-exercise conditions. After 2+ hours of exposure 4 shiver-suppression techniques were applied: voluntary relaxation (R), breath holding (B), mental arithmetic (M), and warm water ingestion (W). Shivering was significantly suppressed by R, B, and M.In Phase II analysis of evoked potentials and reaction times during central and peripheral cooling indicated that cooling methods have differing effects on physiological and physical function.


Distributional properties of the order statistics, upper and lower record statistics have been utilized to characterize distributions of interest. Further, one sided random dilation and contraction are utilized to obtain the distribution of non-adjacent ordered statistics and also their important deductions are discussed.


The radial dependence of line intensities in an impulsive Ne glow discharge was investigated with particular attention being paid to the initial temporal changes of emissive line intensities. Two kinds of discharge tube, a cylindrical hollow cathode (C.H.C.) tube and a plane disk cathode (P.D.C.) tube, were used. The empirical formulae for the radial dependence of the temporal line intensities before reaching the stationary state are presented, with the experimental confirmation that the well-known simple Bessel function type formula is obtained in the C.H.C. at low pressure in the stationary state.


This article is devoted to investment attractiveness evaluation of various art objects. The paper substantiates the use of a matrix of strategic positioning techniques of the art facilities to identify their competitive status in order to reduce market risks for potential investors. The proposed method is demonstrated by the author on the specific example of Russian painting. The article also reveals the impact on the competitive status of the art object brand strength of the auction house, which represents the analyses product.


The network control system for power-(distributed) diesel hydraulic pendulum motor train unit (designed) for Sanmao Railway is described in terms of the configuration,fuctions and display strategy of the system.The combined regulation in laboratory and on train as well as the electromagnetic compatibility test of the system has been compleled.The results show that the system has good (performances) and meets the technical requirements.


A detailed study of the problem of ignition of the intended indirectly driven ''point design target'' [J. Lindl, Phys. Plasmas 2, 3933 (1995)] for the U.S. National Ignition Facility is presented. First a multistep pressure pulse which ignites the target (without its ablator) is found and the effect of changing the timing of the different shocks on the target yield is analysed in detail. A radiation drive which nearly reproduces such a pressure pulse at the ablator/fuel interface is then constructed. The resulting radiation drive is similar to the one used by the U.S. workers but has a 3 percent higher peak value. An operating window of about 35 eV width is found around the optimum maximum drive temperature. Below this window the target fails because adequate implosion velocities are not achieved, while above it the main fuel is raised to high entropies resulting in low compressions, despite high implosion velocities. These calculations represent the first independent confirmation, outside the weapons lab...


We study the effect of the interfacial transparency on the Josephson current in a diffusive ferromagnetic contact between two superconductors. In contrast to the cases of the fully transparent and the low-transparency interfaces, the current-phase relation is shown to be nonsinusoidal for a finite transparency. It is demonstrated that even for the nearly fully transparent interfaces the small corrections due to weak interfacial disorders contribute a small second-harmonic component in the current-phase relation. For a certain thicknesses of the ferromagnetic contact and the exchange field this can lead to a tiny minimum supercurrent at the crossover between 0 and $\pi$ states of the junction. Our theory has a satisfactory agreement with the recent experiments in which a finite supercurrent was observed at the transition temperature. We further explain the possibility for observation of a large residual supercurrent if the interfaces have an intermediate transparency.


We present a generalized definition of scrolling that unifies a wide range of existing interaction techniques, from conventional scrolling through pan and zoom systems and fish-eye views. Furthermore it suggests a useful class of new scrolling techniques in which objects do not move across the display. These "stationary scrolling" techniques do not exhibit either of two problems that plague spatial scrolling system: discontinuity in salience and the undermining of the user's spatial memory.


Abstract : As part of an existing DoD-MURI Center research is being conducted in the field of real time optical process monitoring and control involving a close collaboration between Physicists) Materials Scientists, Chemical Engineers and Mathematicians. In this effort students address specifically closed-loop control of pulsed chemical beam epitaxy (PCBE) of compound semiconductors utilizing a multiple set of optical sensor inputs. These real time techniques are in development under the existing DoD MURI funding, F49620-95-1-0447, entitled "Modeling and Control of Advanced Chemical Vapor Deposition Processes: the Control of Defects in Mixed III-V Compound Heterostructures," of which Prof. Dietz and Prof. Ito are Co-Investigators. These students have worked with Profs. Dietz and Ito on the acquisition of experimental input data for the real-time modeling of PCBE processes and on the development and implementation of control theory algorithms.


A new type of recurrent neural network is discussed, which provides the potential for modelling unknown nonlinear systems. The proposed network is a generalization of the network described by Elman, which has three layers including the input layer, the hidden layer and the output layer. The input layer is composed of two different groups of neurons, the group of external input neurons and the group of the internal context neurons. Since arbitrary connections can be allowed from the hidden layer to the context layer, the modified Elman network has more memory space to represent dynamic systems than the Elman network. In addition, it is proved that the proposed network with appropriate neurons in the context layer can approximate the trajectory of a given dynamical system for any fixed finite length of time. The dynamic backpropagation algorithm is used to estimate the weights of both the feedforward and feedback connections. The methods have been successfully applied to the modelling of nonlinear plants.


This chapter describes the statistical issues involved in analysing studies with more than one data point or observation per subject, such as when a series of measurements are made on each individual over time or when a group of subjects are analysed together, forming a cluster. For each of these situations, the statistical analysis needs to take account of the design of the study, and for most situations there are several possible approaches which may be used. The most common approaches are described in terms of when the methods are appropriate, how they work, and how the results are interpreted.


Observations presented here on floral vasculature in Alpinia hainanensis indicate that the labellum incorporates elements of five androecial members rather than two or three, as suggested by previous authors for Zngiberaceae flowers. The pedicel contains an outer ring and a central region of vascular bundles. Three carpellary dorsal bundles (CDs) and three alternatively arranged parietal bundles (PBs) separate from the central region successively. The remaining bundles of the central region run upwards and become the placental bundles to supply ovules. The placental bundles terminate between the top of the locular region and the base of the prolongation. The three PBs divides into about five strands respectively. Of which the outer strand enters into the petal being its midrib and the remaining strands move into the stamen adaxially being the vasculature of the functional stamen and the labellum abaxially being the lateral strands of the labellum. The three CDs divide into about five traces, of which the outer strand becomes the midrib of each sepal and the inner strand runs into the style. The remaining traces re-unite, re-divide again in the course up and the two adaxial sets of carpellary dorsals finally enter into the labellum being the marginal traces of it while the abaxial single strand enters into the labellum being its midrib. The two antero-lateral glands receive small traces without lignified tube elements from the vascular plexus, which fonn in prolongation from both PBs and CDs and a few small strands in the ovary wall. There are no subulate appendages differentiated in the flower of Alpinia hainanensis. Hereby, the median of the sepals, both the marginal portions and the median of labellum, and the style have the same origin in vasculature from the CDs and so do the stamen, the lateral portions of labellum and the median of the petals from PBs. The labellum is supposed to represent three members of the outer androecial whorl by its two marginal portions and the median and two members of the inner whorl by its two lateral parts except the median.


Rome Laboratory is determining the reliability and electromagnetic (EM) performance of multichip modules (MCM) using an integrated multi-disciplinary analysis and measurement methodology. Simulations and Measurements of EM Effects are used to evaluate the susceptibility of MCM technologies and to determine their vulnerability in their operational environments. EM effects are simulated using modern computational electromagnetic (CEM) analysis techniques to determine the fields within the package. Thermal effects in the MCM are simulated using the Intelligent MCM Analyzer which uses finite-element analysis within a object-oriented data base architecture to determine thermal heating effects. This paper will discuss the results of EM Effects measurements and simulations performed on MCM's to determine their conducted EM performance characteristics. This paper will also assess the feasibility of performing EM effects evaluations with less complex devices and models prior to full scale development. The MCM's evaluated include a MMIC Transmit/Receive (T/R) Module and a High Speed Random Assess Memory (RAM).


Measurements have been made, of lengths and of geometric properties of cross-sections, of the long bones of the legs of a young white rhinoceros of about 750 kg body mass. These are considered in conjunction with data from film of white rhinoceros trotting and galloping. The stresses developed in the bones in running are rather low, in comparison with other large mammals, suggesting that rhinoceros skeletons may be built to unusually high factors of safety. The long, relatively straight legs of elephants (whose bones experience higher stresses) are contrasted with the shorter, less straight legs of the other graviportal mammals.


The idea that specific genes or groups of genes are responsible for the induction or maintenance of cancer is by no means new. Recent research efforts to understand such genetic sequences have focu...


Objective: Recently, many articles reported increased incidence of urinary tract infection (UTI) due to Extended-Spectrum Beta-Lactamase (ESBL)-producing E. coli. No data are available to date regarding patients presenting with complicated upper ESBL-positive E. coli UTI and sepsis. We report the clinical presentation, management, and outcomes in seven cases. Materials and Methods: This prospective study was carried out between January 2008 and September 2011. Follow-ups varied in patients according to their disease presentation and clinical outcomes. All strains were cultured and identified by the Clinical Microbiology Laboratory and were recovered from blood and urine cultures. In-vitro presence of ESBL was confirmed with Clinical and Laboratory Standard Institute double disc method. Results: In the study period, 49 patients needed hospitalization for upper UTI. Overall, in 25 patients (51%), cultures were negative. In the remaining, seven patients (14.3%) presented positive blood and urine-culture for ESBL + E. coli. Of these, four were female and three were male. Their median age was 73 years (range 66-84). The median hospital stay of these patients was 23 days (range 13 to 45 days). Conclusions: The current situation of multiple bacterial antibiotic resistance has become a worrisome issue in UTI. Multi-drug-resistant E. coli can be readily encountered in hospital settings during daily clinical practice, and urologist should act timely. The management of such infections is extremely important for the future, with particular reference to prevention of new antibiotic resistance patterns.


Background and objectives: Colorectal cancer is the third most common cancer and a major cause of morbidity globally. Hepatocellular carcinoma is a leading cause of death in the world. About 80% of all anticancer drugs are somehow related to natural products. One of the most important of these natural compounds is curcumin, the main component of turmeric that has a wide range of pharmacological activities. Curcumin has been found to suppress cell proliferation and decrease cell viability in various types of cancer cells; however, owing to lack of aqueous solubility, curcumin has shown reduced bioavailability in studies. Recent studies have shown that new 400 th generation of dendrosome nanoparticle can increase bioavailability of curcumin and thus enhance the cytotoxic properties. The aim of this study was to determine effectiveness of curcumin alone and in combination with 400 th generation dendrosome nanoparticles (DNC) on cell viability rate in SW480 and Huh7 cells. Methods: SW480 and Huh7 cells were incubated with different concentrations of curcumin and DNC (0-50μM) for 24, 48 and 72 h. Then cytotoxicity was assessed by MTT assay and IC50 was determined. Results: The results suggested that the concentration-dependent inhibitory effect of DNC was stronger than curcumin on SW480 and Huh7 cells. Conclusion: The results suggest DNC as a more effective herbal anticancer agent for colorectal and hepatocellular tumors.


In resonant column testing (ASTM standard), the shear strain distribution along the height of a specimen is assumed linear and fixed at the base. To investigate these assumptions, specimens of dry sand, mine tailings, and cemented sand are tested at different confinement and shear strain levels. The measured mode shapes for dry sands and mine tailings are linear at low and high strain levels; however, for a stiff cemented-sand specimen the first mode shape presents slippage at the end platens. Resonant frequencies decrease up to 50 % while the damping ratios increase up to 200 % because of this slippage. The coupling between the specimen and end-platens is enhanced using three different agents: gypsum cement, portland cement, and epoxy resin. The epoxy resin produces the best coupling, whereas portland and gypsum cements are effective only at low confinements and strain levels. Even after eliminating the slippage at the end-platens, the shear wave velocity of aluminum and PVC probes decreases with the increase in specimen stiffness because of the lack of base fixidity. To correct this apparent reduction, a new model and calibration procedure based on a two-degree-of-freedom system are proposed.


In this research, 1D four-coordinate copper(I) coordination Polymer [Cu(Clba2-1,2-pn)(NCS)]n (1) with thiocyanate anion as bridging ligand, where Clba2-1,2-pn = N,Nʹ-bis(2,4-chlorobenzylidene)propane-1,2-diamine), was synthesized by slow evaporation of solvent at room temperature and characterized by elemental analysis (CHN) and single-crystal X-ray diffraction. Microparticles of 1 were prepared by an ultrasonic bath assisted synthesis and characterized by Scanning Electron Microscopy (SEM) and elemental analysis. Thermal stability of 1 was studied by ThermoGravimetry (TG) and Differential Thermal Analysis (DTA). The structure of 1 consists of 1D polymeric chain in which copper(I) ions are bridged by two thiocyanate groups in an end-to-end fashion, with Cu×××Cu separation 5.686(4) A.


We define a weak form of canonical colouring, based on that of P. Erdos and R. Rado (1950, J. London Math. Soc.25, 249?255). This yields a class of unordered canonical Ramsey numbers CR(s, t), again related to the canonical Ramsey numbers ER(2; s) of Erdos and Rado. We present upper and lower bounds (the latter via a construction) for CR(s, t) which are significantly tighter than the best-known corresponding bounds for ER(2; s).


Michelangelo's The Last Judgment (1534), painted on the rear wall of the Sistine Chapel in the Vatican, is considered by many to be the artist's masterpiece and one of the most important works in the history of art. In this book, the newly cleaned and restored fresco is presented in all its powerful complexity. Richly illustrated with 150 magnificent full-color images- showing the painting both in its entirety and in many close-up details-the book offers an in-depth study of the work itself and of the restoration process. -- CCI=IC


Davidson thus describes the external characters of this species in his Sil. Suppl. pp. 101, 102. The description is practically the same as that which he previously gave in his Sil. Mon. "Marginally of a somewhat elongated, pentagonal shape, truncated, and slightly indented in front, broadest about the middle. Tapering posteriorly. Valves almost equally convex, with a slight median depression near the front in the ventral valve. Beak strongly incurved, and truncated by a minute oval foramen; surface smooth, marked by a few concentric lines of growth. Length 6, breadth 5 lines, but the generality of specimens are much smaller." Davidson refers to the spirals of this species both in his Sil. Mon. and in his Sil. Suppl. Sil. Mon. p. 115: "I had noticed the presence of spirals in 1847, and recorded the observation in the 'Bulletin Soc. Géol. France,' and Lindström has also detected them in a Gothland specimen."


Objective
To explore the clinical efficacy and safety of derotational shortening osteotomy at proximal 1/3 and middle 1/3 of the ulna and radius for the treatment of congenital proximal radio-ulnar synostosis, and to determine the optimal forearm position.

Methods
From February 2010 to April 2016, 36 cases (44 forearms) with congenital proximal radio-ulnar synostosis were treated by derotational shortening osteotomy at proximal 1/3 and middle 1/3 of the ulna and radius. The forearm was fixed at 30° to 110° of pronation before the operation. The forearm was placed in a certain supination position during the operation, and the osteotomy end was fixed with plate and screw. The forearm position was measured at the time of internal fixator removal and last follow-up, and the forearm rotation range after shoulder compensation was measured before and after operation.

Results
All the patients were follow-up for 18 to 72 months, with an average of 31 months. The forearm was fixed at -10° to 80° of supination, with an average of (33. 64±19. 66)° on the left side and (21. 36±14. 51)° on the right side. The degree of correction was 60° to 140°. The range of pronation after shoulder compensation was (188. 18±10. 44)° and (122. 58±20. 43)° before and after the operation respectively, while the range of supination was (-33. 64±33. 52)° and (60. 30±27. 07)°. The difference was statistically significant before and after operation (P 0. 05). The results from the right side were the same as those from the left side. The plate of radius was broken in 4 cases. No complications such as fracture of ulnar plate, nonunion of fracture, deformity recurrence, forearm ischemic contracture and neurovascular injury were observed in all patients.

Conclusion
The derotational shortening osteotomy at proximal 1/3 and middle 1/3 of the ulna and radius is safe and effective for the treatment of congenital proximal radio-ulnar synostosis. Placing forearm at 30° to 50° of supination is better for the function of forearm and hand.

Key words:
Osteotomy; Treatment outcome; Congenital proximal radio-ulnar synostosis; Deformity


Introduction: There are various descriptions regarding blood letting or Raktamoksha using leeches (Jaloukavacharana) in ayurvedic classics. Acharya Susruta considers Rakta as the fourth Dosha and mentions Raktamoksha as a Shodhana karma (purificatory therapy) and is indicated in many diseases with vitiation of Raktha. As a matter of time, leech therapy is becoming more popular due to its benefits but there is no known established reliable suppliers of leeches for medical needs especially for medal purpose, maintenance of leeches in adequate environment, reproduction of leeches and storage of leeches on a large scale. Materials and Methods: This study is based on analysis of classical ayurvedic texts, modern books and internet sources. Some help was also been taken from previous articles published on the same topic. All the relevant information are compiled here. Result: Parameters for successful leech farming are studied and application of these facts can improve leech farming and thus ensure increased availability of leeches for medical needs. Discussion: The increased demand of leeches and its lesser availability forms a challenge especially in extreme weather. Basically, leech farming is a research topic and also an innovative idea for ayurvedic scholars. Leech farming provides special knowledge regarding selection and breeding of leeches


: Coal–water slurry or coal–water mixture (CWS or CWM) is a complex solid–liquid dispersion. Several research works have been done concerning the production and use of CWSs being developed worldwide in several di ff erent governmental, industrial and academic facilities. In the present paper, studies on the developments achieved in the past three decades with regard to the field mentioned above are systematically reviewed, with particular regard to several di ff erent aspects during the combustion process. The structure and properties of the coal are highlighted, as are the di ff erent additives used and their adaptability with di ff erent types of coal, where the particle size distributions are of great importance in determining both the slurryability of coal and the rheological behavior of a produced CWS for its intended characteristics. At a time when there is much debate about the end of the age of coal as a primary source of thermal and electrical energy, alternative forms of use that can contribute to the reduction of pollutant emissions, as well as particles, in the atmosphere o ff er alternatives that may allow us to continue using coal, at least during this transition period until a viable alternative is found. In-depth knowledge of these coal slurries may allow, in the future, the development of similar products produced from fuels derived from biomass, such as charcoal or torrefied biomass.


Activation of voltage gated potassium channels is important for the repolarization of the action potential in a number of systems (for example, the squid giant axon: Hodgkin and Huxley, 1952b; and the frog node of Ran vier: Stampfli and Hille, 1976), though it may not be necessary in others (mammalian node of Ranvier: Chiu, Ritchie, Rogart and Stagg, 1979). Bar rett, Barrett and Crill (1980) reported the existence of both fast and slow voltage-activated outward currents in cat motor neuron es in vivo, and sug gested that the fast component may be involved in repolarization of the fast action potential. However, iontophoretic application of tetra-ethyl ammonium (TEA), sufficient to reduce the amplitude of this fast outward current, caused only a minor increase in the duration of the action poten tial (Schwindt and Crill, 1980; Schwindt and Crill, 1981). Detailed quantitative analysis of conductance systems in cells of the central nervous system is impeded by: 1) Difficulties in adequately con trolling the voltage over the whole cell surface in these geometrically complex cells (Rall and Segev, 1985). The dendritic tree of mammalian motor neurones may have as much as twenty to thirty times the surface area of the neuronal soma (Rall, 1959); 2) The problem of pharmacologically separating the several conductance pathways to characterize the current flow through a single channel type (Schwindt and Crill, 1980); and 3) Limitations in the bandwidth of both voltage recording and voltage control, caused by the necessarily high impedences of electrodes used to voltage clamp these cells. Application of the patch-clamp technique (Hamill, Marty, Neher, Sak mann and Sigworth, 1981) eliminates these problems. It allows investiga tion of a single channel type, under conditions that should permit almost perfect voltage control of the area of the membrane under study. This chapter describes some of the results of a patch clamp study of a fast activating outward potassium current in cultured mouse spinal cord neu rones. The electrical response of this culture system (Ransom and Holz, 1977; Heyer and MacDona1d, 1982; Biltucci, Mclver and Kimura, unpublished) resembles that reported for in vive cat motor neurones (Schwindt and Crill, 1982), and rat spinal cord slices (Murase and Randic, 1983). The aim of these experiments was to obtain aseries of descriptive equations with which to perform modelling of the electrical response of these ce1l types. The analysis has been performed with this in mind.


5G NR (new radio) introduces the concept of massive MIMO (multiple-input multiple-output) technology, in which a larger number of antenna arrays are installed on the transceiver. Due to the increased number of antenna elements allocated close to each other (approximately at a distance of half a wavelength), mutual coupling becomes a serious problem leading to performance degradation of the MIMO communication system. In this communication, two different configurations of closely spaced antenna array elements are studied. In order to reduce the mutual coupling, a combination of a metamaterial-based frequency-selective surface (FSS), a metallic strip, and a slot element in the ground plane is examined. It is found that the proposed technique significantly suppresses mutual coupling from −12 dB to −25 dB. Both designs are fabricated and experimentally validated. The simulation results are in good agreement with the measurements. The proposed mutual coupling reduction technique may be suitable for massive MIMO systems in fifth-generation (5G) new radio applications.


W/Cr codoped Bi4Ti3O12 ceramics, Bi4Ti3-xWxO12+x+0.2 wt%Cr2O3 (BITWC, x=0-0.15), were prepared using a solid-state reaction method. The crystallographic evolution and phase analysis were distinctly determined focusing on the X-ray diffraction peak changes in (020)/(200) and (220)/(1115) diffraction planes, by which the lattice parameters, a, b, and c can be refined. The thermal variations of permittivity, dielectric loss (tan delta), impedance, and electrical conductivity properties were characterized. A decrease in the values of Curie temperature from 675 degrees to 640 degrees C and an increase in the values of the dielectric constant due to an increase of W6+/Cr3+ content were observed. The highest piezoelectric constant, d(33) of 22 pC/N, was achieved with the composition of Bi4Ti2.975W0.025O12.025+0.2 wt% Cr2O3. Also, this composition had a lower electrical conductivity than the other investigated compositions.


A sensitive, accurate and easy indirect spectrophotometric method was developed for the determination of mesalazine in its pure form and in pharmaceutical preparations (tablets, capsules). The method was based on the oxidation of the mixture of the drug compound with the hydralazine reagent by using the oxidizing agent potassium periodate in an acidic medium and in the presence of the surfactant triton (x-100), absorption was measured at 380 nm for the drug compound, and the molar absorbance of mesalazine was 1147.5 liters. Mol-1. cm-1. With a recovery rate of 99.38, the method was developed to be simple, inexpensive and fast because it does not include any solvent extraction. The method has been successfully applied to pharmaceutical preparations.


Characteristics, structure and function of the major interfaces within pratacultural system (grassland livestock production system) were illustrated. Three major interfaces were identified i.e. plant-site interface (A), grassland-animal interface (B) and grassland and livestock-management interface (C). The four production levels within the system are linked by the interfaces and a completed pratacultrual system is then formed. Open and heterogeneous are common features shared by the interfaces. The interfaces act as the boundaries between ecosystems and between ecosystems and non-ecosystems and as the linkage between ecosystems and their surroundings. The opening function of the interfaces results in system coupling, the advanced system is then formed. However, each of the major interfaces also has its own characters, for instance, Interface A is multi-dimensions, whereas Interfaces B and C are only a path with no dimension. The research on interfaces will provide a comprehensive understanding of process and mechanism of grassland ecosystem development, a theoretical basis and scientific strategy of recovery and reconstruction of degraded grasslands. Grassland research methodology will be developed during the process of interface research. Ultimately, the interface research will play a major role in the development pratacultural science and promotion of pratacultural production.


Models of spherical, self-gravitating stellar systems in which all the trajectories pass initially near the center are interesting to examine from different perspectives. Such models are compatible not only with the idea of explosive cosmogony, but also with the concept of formation of stars from a gaseous, spherical cloud, if they are not affected during formation by significant peculiar motions and thus "fall" into the center. Another question is whether such a system is capable of remaining stable for a long period of time. We will show that such a system is unstable with respect to regular forces and must be reconstructed during the course of one period of revolution of an individual star.


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This is to certify that the thesis entitled "EFFECT OF ORGANIC ZINC SUPPLEMENTATION IN THE RATION ON SEXUAL BEHAVIOUR AND SEMEN QUALITY OF GIR BULLS" submitted by CHAUDHARY JAGDISHKUMAR MAFABHAI in partial fulfillment of the requirements for the award of the degree of MASTER OF VETERINARY SCIENCE, in the subject of ANIMAL NUTRITION to Junagadh Agricultural University, is a record of bonafied research work carried out by him under my guidance and supervision and the thesis has not previously formed the basis for the award of any degree, diploma or other similar title. The candidate had fulfilled all prescribe requirements. The assistance and help received during the course of investigation have been fully acknowledged. He has successfully completed the comprehensive/preliminary examination held on February 4, 2017 as required under the regulation for post-graduate studies. He has submitted kachcha bound thesis on AUGUST 21, 2017.


It is shown that the stress tensor can be symmetrised by a proper redefinition of the (linear) momentum density, even if an intrinsic angular momentum is present. The difference between 'intrinsic' and 'external' angular momentum turns out to be a matter of definition. There is no independent hydrodynamic variable due to the angular momentum conservation law. Some expressions for the (linear) momentum density are discussed and the use of the symbol Cij for different quantities by various authors is clarified. The tensor Cij contains two independent parameters by Galilean invariance. Angular monentum conservation including the dipole-dipole interaction is discussed. The orbit wave spectrum shows a quadratic k dependence in the hydrodynamic region and different results are obtained only outside that region or by the use of non-hydrodynamic variables. In two appendices the mode spectrum (with unclamped normal fluid) is discussed and Graham's free energy is explicitly written down.


A competent patient has the right to refuse treatment necessary to sustain life. However, for many end-of-life decisions, we lack direct access to the wishes of a competent patient. Some treatment decisions near the end of life involve patients with severely diminished mental capacity (for example, Alzheimer's patients), some involve patients who are unable to communicate (for example, some stroke victims), and some involve patients who are simply unable or unwilling to participate in decisionmaking due to the nature or severity of their illness.


Relaxation in supercooled liquids above their glass transition and below the onset temperature of "slow" dynamics involves the correlated motion of neighboring particles. This correlated motion results in the appearance of spatially heterogeneous dynamics or "dynamical heterogeneity." Traditional two-point time-dependent density correlation functions, while providing information about the transient "caging" of particles on cooling, are unable to provide sufficiently detailed information about correlated motion and dynamical heterogeneity. Here, we study a four-point, time-dependent density correlation function g4(r,t) and corresponding "structure factor" S4(q,t) which measure the spatial correlations between the local liquid density at two points in space, each at two different times, and so are sensitive to dynamical heterogeneity. We study g4(r,t) and S4(q,t) via molecular dynamics simulations of a binary Lennard-Jones mixture approaching the mode coupling temperature from above. We find that the correl...


, Abstract Background— Concurrent sexual partnerships can increase sexually transmitted diseases (STD) transmission on a population level. However, different concurrency types may be associated with differential risk for transmission. To investigate this, we describe the prevalence and correlates of four specific concurrency types. Methods— Between 2001 and 2004, 1098 young adults attending 3 STD clinics were interviewed and tested for STDs. Characteristics associated with concurrency types were identified using logistic regression. Results— Approximately one-third of respondents reported reactive (34%), transitional (36%), compensatory (32%), and experimental (26%) concurrency. Among men, reactive concurrency was associated with not identifying as heterosexual, drug use, and having sex the same day as meeting a partner. Among women, reactive concurrency was associated with African American race and having >3 lifetime partners. Transitional concurrency was associated with >3 lifetime partners for men and women. Among men, compensatory was associated with African American race; whereas, among women there were no associations with compensatory concurrency. Among men, experimental concurrency was associated with >3 lifetime partners and having sex the same


Minimum vector variance (MVV) is one of the latest contributions in the study of multivariate robust estimators.MVV estimators possess three important properties of a good robust estimator, namely, high breakdown point, affine equivariance and computational efficiency.However, highly robust affine equivariant estimators with the best breakdown point commonly have to compensate with low statistical efficiency.In order to cater this drawback, a reweighted minimum vector variance (RMVV) which is capable of increasing the efficiency while retaining the highest breakdown point is proposed in this paper.A simulation study was conducted to investigate the asymptotic relative efficiency and finite-sample behavior of the estimators for several types of distributions. The numerical results revealed that the reweighed scheme is able to attain higher efficiency compared to MVV estimators.


compared by'haVing subjects learn'three 20-item seriallists. I'n Q. 'addition to the type of.mtemOnic training, listA.magery.was high rated 6-7) or medium (rated 4-5), and instructions Were either.. .progressive elaboiation (e.q.,'make a,single image for each list position across the three lists), imageiy,. or verbal mediatiOn Th't verbal mediation instructions resulted in equal performapce on'both high and medium lists: The, two imagery instructions rqs4lied in higher recall than the verbal:on'high'imagery lists and-lower recall than the verbal on medium imagery lists. Anmisende of serial., ,


The amino acid lysine can undergo methylation, acylation, sumoylation or ubiquitination, making it an extremely versatile protein residue. Its involvement in the modulation of protein biological functions through de/methylation on histones has been well studied but only recently has the focus shifted towards this post-translational modification in non-histone proteins particularly transcription factors. Lysine methylation has been found to act as a switch which can directly alter function or stability, as well as indirectly alter binding affinity to target DNA motifs and protein partners. Lysine methylation has been best-studied in the tumour suppressor p53, making it the ideal transcription factor to showcase how these different mechanisms act. Other transcription factors that undergo such a post-translational modification include NFkB, STAT3 and TFIID. More recently a new family of 10 lysine methyltransferases has been described and the interaction of one of them with the ubiquitous transcription factor E4TF1-60 opens a whole new field of transcription factor control. Lysine methylation is involved in a number of diseases and has also been shown to play a role in tumorigenesis. Targetting specificly modified over-active transcription factors is a potential form of anti-cancer therapy although it is a very delicate process, which still requires extensive research.


Forecasting the future prices of stock by analyzing the past and current price movements in determining the trend are always areas of interest of Chartists who believe in studying the action of the market itself rather than the past and current performances of the company. Stock price prediction has ignited the interest of researchers who strive to develop better predictive models with a fair degree of accuracy. The autoregressive integrated moving average (ARIMA)model introduced by Box and Jenkins in 1970has been in the limelight in econometrics literature for time series prediction, which has been at the core of explaining many economic and finance phenomena. ARIMA models in the research domain of finance and economics, especially stock markets, have shown an efficient capability to generate short-term forecasts and have hence been able to outperform complex structural models in short-term prediction. This paper presents a stock price predictive model using the ARIMA model to analyze the sensitivity of such models to different time horizons used in the estimation of trends and verifies the validity of such forecasts in terms of their degree of precision. Published historical stock data, on an actively traded public sector bank's share and historical movements in the banking sector index in which the selected bank is a constituent, obtained from National Stock Exchange(NSE), India and websites of Yahoo finance are used to build and develop stock price forecasts and index movement predictive models. The experiments with dynamic as well as static forecasting methods used revealed that the ARIMA model has a strong potential for short-term prediction and can offer better precision than from long term trend estimates. As a stock price prediction or index movement forecast tool, it can be relied extensively in deciding entry and exit to and from the volatile markets, notwithstanding the fact the risk the investor faces on account of noise or shocks still can be erroneous making the entire prediction irrespective of its degree of precision irrelevant.


A mixed-integer constrained extension of the RBF algorithm for computationally costly global optimization is presented. Implementation in TOMLAB (http://tomlab.biz) solver rbfSolve is discussed. The algorithm relies on MINLP sub solvers in TOMLAB, currently OQNLP or DIRECT (glcFast or glcSolve). Results for real-life and artificial test problems are presented.


Within the hype of cloud computing, Enterprise Resource Planning (ERP) systems delivered as Software as a Service (SaaS) is receiving more focus from ERP vendors. ERP vendors have for many years developed and sold ERP as 'standard software' that fits the needs of many firms, and now SaaS as a new approach to deliver software has emerged. In this study the value propositions of software as a service from an ERP vendor's perspective is explored. Using semi-structured exploratory interviews conducted amongst 20 Microsoft employees we aim at exploring which perceived benefits are realized by software as a service. Results show that the value propositions of ERP delivered thru SaaS model can be grouped into the following 10 factors: costs, security, availability, usability, implementation, ubiquity, flexibility, compatibility, analytics and best-practices. Been costs concerns, data security and system availability the most important factors.