The use of intelligent machine health monitoring schemes is increasing in critical applications as traction tasks in the transport sector. The high diagnosis capability and reliability required in these systems are being supported by intelligent classification algorithms. These classifiers use calculated features from the system to perform the diagnosis. In this context, different features calculation methods can be applied to characterize the system condition obtaining different classification results. The aim of this work is based on diagnosis capabilities evaluation of the main features calculation methods: statistical features from time, statistical features from frequency, time-frequency distributions and signal decomposition techniques. The features capabilities are quantitatively evaluated by two parameters: the classification accuracy and the discriminant coefficient. Experimental results are obtained from an electromechanical actuator under different diagnosis requirements: from single fault to combined faults detection under stationary and non-stationary speed and torque conditions.


The proper counterexamples can help the students to understand and grasp the mathematic concepts and the theories.In this paper,the typical questions about matrices,polynomial and linear transformation in the advanced algebra were researched.Some counterexamples were constructed by changing the conditions and conclusions,and special matrices and their connections,polynomial divisibility were further studied.The research about the counterexamples has a better significance for higher algebra teaching.


The main focus of the paper is the development of technological route of the production of complex 3D microstructure, from designing it by the method of computer generated holography till its physical 3D patterning by exploiting the process of electron beam lithography and thermal replication which is used for biomedical application. A phase data of a complex 3D microstructure was generated by using Gerchberg-Saxton algorithm which later was used to produce a computer generated hologram. Physical implementation of microstructure was done using a single layer polymethyl methacrylate (PMMA) as a basis for 3D microstructure, which was exposed using e-beam lithography system e-Line and replicated, using high frequency vibration. Manufactured 3D microstructure is used for designing micro sensor for biomedical applications.


Diuretics have been the standard treatment for heart failure for several decades. The primary action is renal in promoting diuresis, but diuretics also alter vascular conductance and this may enhance their efficacy in heart failure.' The syndrome of chronic heart failure is associated with changes in vascular conductance peripherally and it is appropriate to summarise those changes before reviewing the vascular effects of diuretics.2' Patients with chronic heart failure, who are stabilised on treatment, are encouraged to exercise as part of modern management.4 Training improves exercise capacity. Exercise has been shown to alter vascular reactivity favourably both in normal people and patients with heart failure.5 6 In chronic heart failure the resting cardiac output initially remains normal but is reduced during exercise. Also the normal physiological redistribution of blood flow to exercising muscles during exercise is decreased. This redistribution is achieved by muscular vasodilatation and splanchnic vasoconstriction. As the severity of heart failure increases both the resting and exercise cardiac output decrease and the redistribution is less, so that regional blood flow to exercising muscles and elsewhere is reduced.7 Vascular compliance is altered in heart failure. Both arterial and venoconstriction occur, and the muscular arteriolar bed becomes less able to vasodilate than normal. This is a


How did human language arise, and what accounts for its present structure? Over the past decade, there has been great interest -- and impressive progress -- in using evolutionary theory to address to these and related questions. In particular, a number of studies have shown that several key features of language could plausibly arise and be maintained by natural selection when individuals have coicident interests. However, these models have largely ignored a vital strategic component of the social context in which language is employed: individuals in real societies, both past and present, do not have fully coincident interests. Simultaneously, theoretical models of animal communication have confronted these strategic issues head-on, but they have largely focused on costly (Zahavian) signals. We approach this problem directly, asking the following question: Can language evolve and be maintained under common biological scenarios of non-coincident interest? Using a trio of examples -- the peacock, the sparrow, and human language -- we show that an explicit connection can be drawn between "costly signalling theory" as developed for the study of animal communication, and the "cheap" signals employed in human language. We argue that coincident interests are not a prerequisite for linguistic communication, and explore the structural features to be expected of languages employed in societies with non-coincident interests. We find that many of the results derived previously by assuming coincident interests will also be expected under less restrictive models of society.


The outcomes of flood management are uncertain since climate change and urban densification are expected to result in higher amounts of surface runoff, and both these changes are subject to uncertainty. When uncertainty is deep, there is a need for strategies to treat uncertainty, e.g. taking the limitations of quantification by probabilities into account, and to guide decisions to be robust to uncertainty. In this masters thesis, a multi-criteria decision analysis (MCDA) is derived for comparing flood management measures, including their robustness to uncertainty. Performances of management measures are assessed based on five decision criteria evaluated under six scenarios, representing different states of urban densification and climate change, and six decision rules, testing the sensitivity to how uncertainty is taken into account. The resulting robust decision analysis was applied as a case study on an urban area in the municipality of Lund, Sweden. (Less)


ABSTRACT Harmonic currents and voltages appearing on a building's AC 7 power distribution system are a form of power quality (PQ) problems. In some cases these problems may be so slight as to be non-existent from a practical standpoint and so may be dismissed. Remember, just because modem test equipment such as a harmonic analyzer or power line analyzer (PLA) can detect and report on the harmonic currents and voltages for the circuit being examined, the presence of these conditions does not automatically mean trouble. Other common forms of power quality problems involve wiring system design, load-power source impedance interactions, switched on-off loads, and the unwanted effects of magnetic fields due to current flow in conductors of all types. This article briefly describes the above problems and provides some time-tested methods for dealing with their most common forms.


Light field capture and display technologies have been rapidly emerging in the past decade. The high dimensional design space of light field systems, however, imposes new challenges for end to end system design and evaluation. We discuss design principles for task specific light field camera systems and outline how such principles can be applied to or need to be modified for the design of personal light field displays.


Finite Temperature Hartree Fock (FTHF) calculations have been performed in 4He in a quasiparticle basis which contains nucleons as well as Δ(1232) isobars. For temperatures less than 10 MeV, the isobar admixture probabilities are negligibly small.


Insomnia is a common sleep disorder in clinic. Compared with western medicine treatment, acupuncture and moxibustion are two operations, which are noninvasive, convenient, safe, and effective, without side effect. Insomnia has its unique advantages. This article aims to improve understanding of acupuncture treatment of insomnia. Methods: It analyzes the acupuncture treatment of insomnia on the etiology and pathogenesis, principle of choosing acupuncture point, treatment method, retrieving for nearly 10 years of relevant literature, counting the frequency of acupuncture points.


International Criminal Court is the first permanent international criminal tribunal in human history. Its establishment has been hailed as a milestone in the developing history of international criminal law. However, it remains to be proved in practice whether International Criminal Court can effectively punish and prevent the crimes within its jurisdiction. From the perspective of the principle of double criminality and relevant international instruments, the effectiveness of extradition appeal of International Criminal Court is discussed in this paper. It is held that if the Court wants to punish a criminal under its jurisdiction, extradition would be the first barrier for it to overcome. .


: The tendency for sedentary lifestyle and avoidance of physical exercise is observed in all age groups, even in scho- olchildren. The effect is a growing number of people with overweight or obesity among the population of children and adolescents who complain about back pains and deteriorating quality of body posture. Material and Method: the study covered a group of 90 children aged seven, including 45 girls and 45 boys. The measurements of body weight and height as well as thickness of abdominal skin-muscle fold have been performed. As many as 180 plantocontour- grammes with the Clarke angle were drafted. The longitudinal axis of the lower limb was assessed by means of mea-suring of genu valgum and varus degree using linear calliper. Results: no significant statistical differences between girls and boys were found as far as body weight, height and fatness are concerned. In 45% of the studied girls and 65% of the studied boys a lowering of a longitudinal arch was observed. Genu valgum was found in 31% of girls and 15.5% of boys. Varus position of the lower limbs was noticed only in 2% of the surveyed girls. This deformity did not occur among the studied boys. Applying the Spearman rank correlation coefficient (p < 0.05) revealed a strong relation bet- ween body weight and the thickness of skin-muscle fold, and the knee position. The Pearson's coefficient designation for the relation between the thickness of the skin-muscle fold and the BMI value, and the foot longitudinal arch indi- cates a lack of strong correlation. Conclusion: fixed pes planus is a condition frequently occurring in 7-year-olds, es-pecially boys. Fatness, as well as the positioning of the lower limbs, do not influence, in a significant manner, the degree of feet arching. Excess quantity of fat tissue demonstrated in an increased body weight and the thickness of the abdominal skin-muscle fold raise the probability of valgum position of the knees in children of both sexes.


It is shown that by truncating the impulse response of an ideal 2D low-pass filter, the same impulse response can be realised by 2D finite impulse response (FIR) filters. However, the contours of the frequency response have to be taken into account while doing so. Two specific contours, namely rectangular and circular boundaries, are discussed in detail.<<ETX>>


It discusses the influence of cattle raising activity in the deforestation of the State of Rondonia, in the Brazilian Amazon, due to its late, rudimentary and without planning deployment, and if there was a social and economic contribution to the State. It is a bibliographical and qualitative research, in which, were raised information about the cattle breeding in the State, during the last five decades, in which they gave the occupation of Rondonia. It has the objective of showing the configuration of the activity in the regional development. It extracted that only, from the 1970s, was that the cattle breeding became important for the regional economic, but there was a lack of public ordering policies and a planning of the occupied territory, becoming in a competitive activity. Here, the low technologies provoked the replacement of the forest by the extensive creation, and, it is known that the cattle exploitation made in a right way, causes just a few damages in its operation area or little damage occur in their area.


PURPOSE: A device and a method for tracing a location are provided to easily trace the location of an object in a limited space such as home or an office by using a portable terminal which includes a RFID(Radio Frequency Identification) reader. CONSTITUTION: A positioning device comprises a RFID reader(110), a distance calculator(130), and a display unit(150). The reader receives a response signal from a RFID tag after sending an recognition signal to the RFID tag. The recognition signal and the response signal are radio frequency signals. The reader measures the strength of a response signal received from the RFID tag. The distance calculator generates information on the distance between the positioning device and the RFID tag based on the strength of the signal. The display unit displays the distance information generated by the distance calculator.


This paper proposed that a more flexible approach to the development of teaching groups, accompanied by the necessary changes in staff and facility utilization, would help solve problems arising from declining enrollment in elementary schools. Such problems, presently occur in many elemenlary schools in Western Canada. The problems of educational planners in dealing with declininOenrol,tmentsare examined in terms of school organization, staff utilization and the utilization of facilities. Traditional bases for classroom grouping in elementary schools include age, ability, program and handicap. There is no evidence that any of these groupings promotes achievement. Recent research on the teachable group has confirmed that the "fit" between a group of students and the teachers is an important basis fo: grouping. It did not improve student achievement but did improve student grades as well as studenr and teacher satisfaction with class sessions. Proposals especially appropriate for elementary schools with less than 150 students in 8 grades are illustrated in four models for classroom grouping. Two Models assume that teachers can develop teachable groups and a variety of activities; that students can benefit from extensive individualization of curricula and changeable groupings; and that school faci4ities can be modified so as to allow a variety of groupings. Two other Models are more traditional and suitable for schools whose physical structures are not easily changed. Changes in staff utilization would necessarily follow innovations in grouping and would include a greater emphasis on professional activities, with clerical duties being delegated to teacher aides. There would also be a greater emphasis on cooperation in planning instruction, including team teaching. Studies have shown that team teaching in open-space schools offers advantages for both students and teachers. The four models suggested would allow for a more economic pupil-teacher ratio, thereby controlling costs to some degree. Changes in facilities would be relatively minor, making use of present buildings by removing partition walls. In addition, well-equipped libraries with special emphasis on resource centers and audio-visual aids are essential to the high level of individualization of instruction involved in this type of classroom -grouping. Implementation of these proposals might improve the quality of education in areas of declining enrollment, while keeping costs down. Declining enrollments present problems to planners at the school J,vision level which can be considered in three categories: school organization; staff utilization; and the utilization of facilities. A brief examination of The general problem precedes detailed treatment of each category. Declining enrollments in the elementary school characterize the whole of Canada at present, with the exception of the Yukon End the Northwest Territories. Between 1970-1971 and 1974-1975 enrollments in kindergarten and elementary classes are expected to fall by 8.68%. (Statistics Canada, 1972) The problem seems particularly acute in Manitoba and Saskatchewan, where elementary school enrollments are declining somewhat more rapidly than for Canada as a whole, and unevenly across the provinces. In Manitoba, there is some evidence that enrollments in the metropolitan Winnipeg area are stable; hence the decline will be felt primarily in rural divisions, which enroll about half of Manitoba's elementary school students. For these divisions, the decline will be nearer 16% per year then. In Saskatchewan the trend seems similar. (Scharf, 1972) These declining enrollments come to the attention of school administrators and school boards in several ways: sparse populations spread over a wide area result in heavy transportation costs per student; age-ranges in classes become larger as several grade-levels are amalgamated into a single classroom; teacher workloads rise with increasing heterogeneity of classes, and consequently pupilteacher ratios tend to fall; the provision of special programs becomes more and more difficult and costly; finally, it may become difficult or impossible to keep some small schools open at all. The aeneral solution to these problems has been to close small schools aria redistribute their populations so as to improve the viability of the remaining schools. However, this increases the transportation problem, and there is clearly a limilation to the amount of time elementary school students can spend on school


MOCVD grown Al1-xInxN/AlN/GaN heterostructures have been characterized by atomic force microscopy(AFM) in semi-contact and conductive mode. The surface of In-related alloys consist of grain-like structures indicating step flow and 3D-growth with TDs of density equal to ∼108/cm2, the origin of which is mostly attributed to lattice mismatch between GaN and sapphire. These TDs with screw or mixed components terminate at the surface of overgrown layers as V-defects, which are six-facetted inverted pyramidal structures. Strain relaxation mechanism, formation of cracks and its propagation to the surface of the samples have been also investigated. With phase-imaging (in semi-contact AFM), we have traced sites of indium segregation in the V-defects, surface-relaxation and crack propagation in In-related alloys. These sites in V-defects and cracks were found to be highly conductive by current-AFM either due to the presence of In-segregation or due to lowering of potential barrier as a consequence of strain-relaxation. They may be the possible dominant cause of leakage current in Schottky diodes. (© 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)


Soils contain a large amount of
carbon (C) that is a critical regulator of the global C budget.
Already small changes in the processes governing soil C cycling
have the potential to release considerable amounts of CO2, a
greenhouse gas (GHG), adding additional radiative forcing to the
atmosphere and hence to changing climate. Increased temperatures
will probably create a feedback, causing soils to release more
GHGs. Furthermore changes in soil C balance impact soil fertility
and soil quality, potentially degrading soils and reducing soils
function as important resource. Consequently the assessment of soil
C dynamics under present, recent past and future environmental
conditions is not only of scientific interest and requires an
integrated consideration of main factors and processes governing
soil C dynamics. To perform this assessment an eco-hydrological
modelling tool was used and extended by a process-based description
of coupled soil carbon and nitrogen turnover. The extended model
aims at delivering sound information on soil C storage changes
beside changes in water quality, quantity and vegetation growth
under global change impacts in meso- to macro-scale river basins,
exemplary demonstrated for a Central European river basin (the
Elbe). As a result this study: ▪ Provides information on joint
effects of land-use (land cover and land management) and climate
changes on croplands soil C balance in the Elbe river basin
(Central Europe) presently and in the future. ▪ Evaluates which
processes, and at what level of process detail, have to be
considered to perform an integrated simulation of soil C dynamics
at the meso- to macro-scale and demonstrates the model's capability
to simulate these processes compared to observations. ▪ Proposes a
process description relating soil C pools and turnover properties
to readily measurable quantities. This reduces the number of model
parameters, enhances the comparability of model results to
observations, and delivers same performance simulating long-term
soil C dynamics as other models. ▪ Presents an extensive assessment
of the parameter and input data uncertainty and their importance
both temporally and spatially on modelling soil C dynamics. For the
basin scale assessments it is estimated that croplands in the Elbe
basin currently act as a net source of carbon (net annual C flux of
11 g C m-2 yr-1, 1.57 106 tons CO2 yr-1 entire croplands on
average). Although this highly depends on the amount of harvest
by-products remaining on the field. Future anticipated climate
change and observed climate change in the basin already accelerates
soil C loss and increases source strengths (additional 3.2 g C m-2
yr-1, 0.48 106 tons CO2 yr-1 entire croplands). But anticipated
changes of agro-economic conditions, translating to altered crop
share distributions, display stronger effects on soil C storage
than climate change. Depending on future use of land expected to
fall out of agricultural use in the future (~ 30 % of croplands
area as "surplus" land), the basin either considerably looses soil…


Current wireless power transmission techniques, in combination with the large integration in silicon devices and ultra-low power integrated circuits have enabled the use of RFID tags as sensors. Because RFID tags can be used as a communication interface for data transmission, but also as energy harvesters, it becomes attractive for wireless and battery free applications. Taking advantage of that, a prototype for temperature monitoring in connecting rod bearings RFID tag was developed based on a commercial device. The tag is integrated with a microcontroller and a signal conditioner, which is connected to thermocouples that measure the temperature of the bearings. The tag moves with the connecting rod, while performing the measurements and reporting them to the reader. However, as the tag moves away from the reader, during the crankshaft revolution cycle, their communication is interrupted. To address this problem, a redesign of the reader coil is proposed in this work. To minimize operating condition changes at the reader circuit, the geometric variables of the coil were recalculated while keeping its electrical parameters constant. However, the interaction of the RFID interface with the metallic parts inside the machine deteriorates its performance, causing a strong reduction in the expected communication range. Therefore, an experimental evaluation was performed, to measure the effects of the coil interaction with the environment inside the machine. To compensate these effects and extend the communication range, a tuning procedure of the reader circuit was carried out and the power emitted by the reader had to be increased. As result, the communication range was extended to the required value, guaranteeing the link between the reader and the tag throughout the entire revolution cycle of the crankshaft.


On the foundation of analyzing the manner of increase by the government's investment and the export,the article probes the manner of increasing consumption, suggesting that the raising consumption level can not only develop national economy,but also build harmonious society,and realize socialist production objective.


Wendeng milk goat is a crossbreed which had come from Shaneng milk goat of formal Northwest Agricultural University and local goat since. 1979 after directive breeding, formed the new breed of Shandong domestic animal. It has the special evolution quality in biology, ecology and milk production. But there is no special topic in the text books. This essay shows us its introduction, directive breeding plan, breed characteristics and its productive capability.\;


This paper seeks to theoretically explore the role of emotion in designing products that consumers will love and use for long. The new insights on value of product and visual perception are drawn from interdisciplinary scholarship: 1) product value consists of "utilitarian and hedonic values", 2) product personality consists of "semantic and symbolic personalities", and 3) product form consists of "shape and surface". These perspectives have been developed into patterns of consumer purchase and possession that are defined by the degrees of utility and emotional attachment that the product offers to consumers. Subsequently, a possible way of managing a consumer's psychological process towards a decision of "desired purchase" will be illustrated. Finally, these discussions of emotionally attractive products will be integrated with the emergent research area of artificial intelligence for consideration of future production.


We examined relations between cumulative levels of forest harvesting and density of road networks on the occurrence and abundance of bull trout (Salvelinus confluentus) in the Kakwa River Basin, Alberta. Logistic regression models showed that bull trout occurrence was positively related to stream wetted width but negatively related to percent fines, percent cobbles, reach slope, and the cumulative area of the subbasin harvested and road density. Results from zero-inflated Poisson regression models typically showed that bull trout abundance was positively related to elevation and negatively related to stream width, percent fines, percent cobble, slope, and levels of forest harvesting. Using the negative relation between bull trout occurrence and percentage of subbasins harvested derived from the most parsimonious logistic regression model, we forecasted that forest harvesting over the next 20 years is projected to result in the local extirpation of bull trout from 24% to 43% of stream reaches that currentl...


In this work we study a generalized nonlocal thermistor problem with fractional-order Riemann–Liouville derivative. Making use of fixed-point theory, we obtain existence and uniqueness of a positive solution. Mathematics Subject Classification 2010: 26A33, 35B09, 45M20.


This paper of mine rescue team members the principles of physical training,characteristics,content and methods of related issues such as study,based on the combination of North China Institute of Technology Center for Safety and technical training specific situation,mine rescue team members to develop compliance standards for physical training.


The dissolution behavior in vitro of naproxen sustained release tablets prepared with hydroxypropyl methylcellulose as the main excipient was investigated.The result suggested that the drug release fitted oneorder kinetic mechanism (Kr=0.0903,r=0.9968) and was effected by the pH of dissolution media,dissolution method and rotation speed.


A Regardless thickness of the film, and to provide a cutting auxiliary line forming method of the auxiliary cutting line that is cleavable at a predetermined line can be formed on the film. A configuration and comprising a film of packaging material or the packaging material A for packaging food, in a state sandwiched between the horn and the receiving member ultrasound is applied, the films by applying ultrasonic waves to the horn dissolve an auxiliary cutting line forming method for forming a groove-shaped auxiliary cutting line on the film, the receiving member, at least one direction of the width of the tip portion sandwiching the film with a horn is formed narrower toward the distal end the ultrasound was applied to the horn while applying a tension in a direction perpendicular to the width direction of the distal end portion of the receiving member relative to the sandwiched film and the horn and the receiving material, the width of the tip portion of the receiving member on the film forming an auxiliary cutting line extending in a direction perpendicular to the direction. .FIELD 1


This application note describes the sampling and analysis of a challenging range of trace-level volatile and semivolatile vapors of perfluorinated and polyfluorinated alkyl substances (PFAS) in air. The analytical system used combines the Agilent 8890 gas chromatography (GC) system with the Agilent 5977B Series gas chromatograph/mass selective detector (GC/MSD), and the TD100-xr automated thermal desorption (TD) system from Markes International, which operates without a liquid cryogen coolant and complies fully with relevant international standard methods. 1–5 Excellent method performance (linearity, repeatability, and storage stability) was demonstrated across the range of compounds tested, including low- or sub-parts per trillion (ppt) detection limits for all compounds. The study also demonstrates the benefits of using quantitative TD sample re-collection for validation of analyte recovery through the entire analytical TD process. Quantitative TD sample re-collection is a relatively recent TD innovation. It overcomes the one-shot limitation of traditional TD technology, and allows samples or standards to be rerun for data confirmation and/or repeat analysis using different conditions, such as split flows, GC columns, detectors, and so on. The study analyzed 18 representative PFAS spanning several classes, and method performance was evaluated, including blanks, linearity, limits of detection (LODs), and precision. Finally, real ambient air samples were also analyzed.


The resistance to abrasive wear of composite materials obtained using electrodepositing in nickel and copper matrix was studied. The samples containing composite layers of graphite in copper matrix, titan dioxide and zirconium dioxide in nickel matrix were subjected to the wear process using a pin-disc type testing machine.


Due to the huge system in the field of constitution, the content of cases is complicated, and the number of documents related to constitutional cases is huge. It is incredibly tough to find the information that suits your demands in such a large volume of constitutional documents. The artificial neural network-based deep learning method has made significant progress. Deep learning has been used in the disciplines of computer image and video processing, as well as natural language processing, and has outperformed typical machine learning methods. To that purpose, the content-based recommendation algorithm in this work is improved using deep learning approaches. This paper primarily covers the following topics: (1) the current research status of deep learning technology in recommender systems is reviewed, and the theoretical knowledge of deep neural networks is introduced. (2) A text classification model OCCNN based on character-level convolutional neural network is proposed to solve the problem of document classification of massive cases. A semantic similarity calculation model TF-W2V based on word frequency and word vector is also proposed to solve the problem of semantic similarity calculation of cases. (3) The two methods are tested, and the experimental results show that the accuracy is much higher than that of the conventional method. The model can recommend cases that meet the needs of users according to the requirements put forward by users in the process of handling cases.


Oral cancer is a major public health concern in Asian countries, with India alone contributing 34% of the global incidence. Oral squamous cell carcinoma (SCC) is the most common. Carcinogenesis is a complex process in the development and progression of cancer. Delay in oral cancer diagnosis remains one of the major causes of high morbidity and mortality. Non-invasive methods such as liquid biopsy are being explored as biomarkers in the body fluid of individuals affected by oral cancer. Small non-coding RNAs called microRNAs (miRNAs) regulate gene expression, which plays an important role in the pathogenesis of cancer. This short communication further enlightens the knowledge of miRNA and its implications for oral cancer.


Forests around the world are under stress. Due to increased global warming, they must adapt ever more rapidly to climatic fluctuations and accompanying extreme events. This leads to tree dieback and reduced growth, leading to less carbon absorption. In concert with increasing emissions, these factors help drive climate change. Furthermore, ecosystem services such as climate regulation, water storage and the provision of materials, e.g., for building, also decline.


where 52 is an open subset of some real Banach space V, the unknown function U: r(2 + R is to be continuous, Du(x) denotes the Frechet derivative of u at XE Q (and thus takes its values in the dual V* of V), while the nonlinear function F is a continuous mapping from Q x R x V* into R (i.e., FE C(Q x R x V*)). In Part I [9], we showed that general uniqueness results hold for Hamilton-Jacobi equations in infinite dimensional spaces for the same type of generalized solutions, the so-called viscosity solutions, for which uniqueness was proved in the "classical case" V= RN in [7] (see also Crandall, Evans, and Lions [S]). Corresponding existence results were proved in Part II [lo] under essentially the same assumptions on the equation and V as used for uniqueness. Various counterexamples showing the necessity of the assumptions on the equation were also given in [9, lo]. A basic assumption made in Parts I and II was that I/ has the


The need for high-resolution and high-speed detection of line scale graduations is a result of increasing throughput requirements of precision scale calibration systems. These new demanding requirements can be met by exploiting the advantages of the dynamic mode of calibration. The state-of-the-art platform-based approach to improving calibration systems performance will allow both functional extension to already deployed systems and the design of new ones, capable of adapting to different application patterns and user profiles. An interferometer-controlled comparator setup has been designed to measure the performance of the dynamic calibration process. A novel 3D finite element model has been developed in order to both investigate thermo-mechanical processes in the comparator structure and evaluate possible temperature influence on geometrical dimensions of the line scale. A series of measurements has been conducted at PTB and MIKES length calibration laboratories in order to evaluate the capabilities of the dynamic calibration of graduated line scales.


FLOODsite is an Integrated Project under the EC 6th Framework Programme and comprises over €14M of research work being undertaken by 36 partners, drawn from 13 different countries. Management and implementation of the project is particularly driven by the complexity and volume of work, the number and distribution of partners and the variety of target/stakeholder groups. Use of the web as a management and implementation tool seemed the most effective approach. From the outset, three core objectives of the website were to facilitate research dissemination, team building and project management. A range of web tools have been developed and applied during the past 2 years – some successful, some not so effective. Fundamental to their effectiveness is their functionality and usability. This paper provides an overview of the web based work within FLOODsite, highlighting the concepts applied and giving examples of approaches and tools that have worked well and some that have not worked so well. The se findings should be of value to any project manager considering how to make effective use of the web for facilitating large technical projects.


Adenoids and hypertrophy of the tonsils occur in all kinds of people and give rise to numerous symptoms. The first group of these comprise oral breathing and its injurious consequences, nasal breathing being hampered. Since the adenoids mostly close only the upper part of the choanae, it is possible for the air to circulate through the small opening which remains free on the inferior part. But if there is an accumulation of mucus, or if the inflamed adenoid tissues are swollen, the obstruction may temporarily become complete. The disturbances in expiration usually begin earlier, since the adenoids are pressed into the opening of the choanae by the circulating air and set up a valvelike obstruction. The patients breath through the mouth, and when they lie horizontally the tongue slips back, so that even oral breathing is obstructed under such circumstances. The disturbances are even more serious if the tonsils are enlarged, and besides this, sometimes hypertrophy of the tonsilla lingualis increases the dif...


Last year brought important criticisms of the use of rational model-building: from staff-members of the WA Department of Transport, two laments which may be construed as being about how hard it is to embody public preferences in transport policy; and from a firm of consultants, a denunciation of the use of cost-benefit analysis, at least in complex situations such as that of the third runway at Sydney airport. This paper argues that, on the contrary, rational economic modelling is essential for successful handling of the problems to which the critics refer. In particular, such modelling helps in addressing distributional consequences, that is, who gains and who loses, and by how much. The paper concludes with some 'modest' suggestions on how to attend to the interests of the losers.


Abstract. Land subsidence caused by large-scale engineering
construction may damage the surrounding infrastructures and cause huge
economic losses in inner-city environments. In this study, we used PS-InSAR
technology on 68 TerraSAR-X images to acquire deformation in the Beijing
Plain between February 2010 and December 2018. Then, we calculated the
additional stress derived from building loads using the method proposed by
Boussinesq in the Central Business District (CBD). We found that the depth
of influence of additional stresses induced by building loads was 80 m and
that spatial distribution pattern of the land subsidence rate agreed well
with the additional stress. We found that the influence range of ground
subsidence caused by metro construction is 200 m at Ciqikou station by
analyzing the subsidence rate profile perpendicular to subway line No. 7 and
that the maximum land subsidence rate is 23.2 mm yr −1 . Time series
analysis of PS around Ciqikou station shows that land subsidence caused by
excavation activities mainly occurs in the period of metro construction.
Ground deformation rate decreases gradually after 372 d of subway
operation. The results of both cases show that large-scale engineering
construction will lead to significant land subsidence which should be
considered in future urbanization.


The potential for using cost-benefit analysis in air quality management is assessed. Definitions and concepts used in cost-benefit analysis are explained, and the steps required to derive a quantitative estimate of the costs and benefits of a particular management strategy are described. Difficulties in the use of such analysis are discussed. Problems of translating biological, chemical, physiological, and physical effects into monetary terms are explored. (2 diagrams, 1 photo)


A realistic reduced model involving a large poloidal spectrum of microtearing modes is used to probe the existence of some stochasticity of magnetic field lines. Stochasticity is shown to occur even for the low values of the magnetic perturbation δB/B devoted to magnetic turbulence that have been experimentally measured. Because the diffusion coefficient may strongly depend on the radial (or magnetic-flux) coordinate, being very low near some resonant surfaces, and because its evaluation implicitly makes a normal diffusion hypothesis, one turns to another indicator appropriate to diagnose the confinement: the mean residence time of magnetic field lines. Their computation in the microturbulence frame points to the existence of a disruption limit, namely of a critical order of magnitude of δB/B above which stochasticity is no longer benign yet leads to a macroscopic loss of confinement in some tens to hundred of electron toroidal excursions. Since the level of magnetic turbulence δB/B has been measured to grow with the plasma electron density this would also be a density limit.


Tuberculosis has been one of the most important infectious diseases in human history, which causes deaths of 2 million people around the world annually (1). Inhalation of 1 3 bacillus Mycobacterium tuberculosis is sufficient for infection with this bacterium. According to the existing reports, almost one-third of the world's population is infected with M. tuberculosis, although they may not show any symptoms of this disease (2, 3). Due to the spread of HIV epidemics in the world, and emergence of the drug-resistant strains of Mycobacterium tuberculosis (DR-TB), eradication of tuberculosis is impossible (1).


1. In analysing the ecological conditions of an animal population we have above all to focus our attention upon the most sensitive stages within the life cycle of the animal, that is, the period of breeding and larval development.


The purpose of this paper is to present the lessons learned during implementation of the Mechanistic-Empirical Pavement Design Guide (MEPDG) and to provide a detailed framework on how to validate the design guide using level 3 inputs. The performance models in the MEPDG were calibrated using Long Term Pavement Performance (LTPP) data from highway sections all over the United States. Therefore, the design guide with level 3 inputs must be validated for soil, environmental and traffic conditions typically observed in a specific region. In this study, accurate input and performance data from seven LTPP sections in the state of New Jersey were obtained. To ensure accurate data were used in the design guide, the data were collected from multiple sources, such as the as-built plans and NJDOT databases. A case-by-case comparison was conducted between predicted and measured performance data for every section and each distress, such as rutting, fatigue cracking, longitudinal cracking, transverse, cracking and roughness. The analysis determined the conditions where the level 3 inputs may not be appropriate. This step is critical before any state agency starts implementing the design guide. This paper provides the state agency with the tools and the knowledge needed to successfully implement the design guide. The framework will also serve as practical guide to state agencies and research institutions as the pavement community begins to adopt the new design guide.


The invention provides a pavement crack detection system based on image, which comprises a control module, an image acquisition module and a data processing module, wherein the control module can be used for generating a trigger signal according to the received GPS location information and outputting the trigger signal into the image acquisition module; the image acquisition module is used for acquiring image of road surface and road signs according to the received trigger signal so as to acquire the image of the road surface and the road signs, and outputting the image of the road surface and the road signs into the data processing module; and the data processing module is used for mosaicking first digital image to obtain continuous digital image of the road surface, utilizing an image identification method for indentifying the crack in the continuous digital image of the road surface to obtain first digital image containing the crack, the GPS location information and second digital image, and determining the position information of the pavement crack according to the GPS location information and the second digital image for outputting. The invention also provided a pavement crack detection method based on the image. Therefore, the system and the method can improve the accuracy and the efficiency of detection.


- The focus of this paper is to theoretically investigate about different organisational capabilities. Understanding about the organisational capability can support organisation to draft strategies and invest directly to the capabilities which has better outcome in terms of business performance. This study focuses on organizational capabilities such as innovation, supply chain management, manufacturingR&D,and marketing and their effect on organizational performance with strategic implications.Organisational capabilities show their presence through organisational processes and are source of competitive advantage. The focus of research is to investigate about marketing capability and associate its relevance in B2B setup.The model of organizational capability and market share as business performance outcome proposed in the paper is one of the useful platform to understand dynamic capability and implementation of capability to solve business bottlenecks. Paper focuses on theoretically conceptualizing and creating platform for research scholars for further extension of this research in the form of empirical study. It would also be useful for managers to benchmark their marketing strategies.


Clustering engineering students in the residence halls has proven to be a successful strategy for student retention at the University of Wyoming (UW). This model is based on the highly successful theme floors offered by many housing departments on campuses across the nation. Since the first students that were selected to live on the Engineering Floor during the Fall 1995 semester, an ever-increasing number of students are choosing this arrangement, an indicator of the success of this living arrangement. A survey, conducted to ascertain student attitudes about the living environment and the perceived benefits of the program, is discussed in this paper. Students are very positive about the innovative living environment. Improved retention and academic performance statistics are reported, thereby demonstrating that the Engineering Floor is an effective method of improving student success in engineering programs.


This study attempts to analyze the current performance management system of a restaurant to present a solution in the form of the new performance management system. A PMS and performance appraisal form have been made with an effort to provide a solution in Urdu that is best suited to the requirements of all the branches of the restaurant across Pakistan. It further deals with explaining the responsibilities of the selected groups of employees. These groups of employees included the back end and the front-end staff of the employees. This study gave the basis for analyzing the presently practised performance appraisal in the restaurant which helped to identify the pitfalls and the gaps prevalent in their appraisal system of the performance of the employees. Several visits were made to the various branches of the restaurant, interviews were conducted, and data was gathered that helped in analyzing the prevalent system. The study formulates a hypothesis based on relevant literature about using the present system of appraisal and the criticality of its ineffectiveness. The study of the whole system being practised.


The arƟcle reveals the role of employee moƟvaƟon of agricultural enterprises in terms of innovaƟve development. In modern condiƟons of innovaƟon development there is an insufficient level of employee moƟvaƟon of agricultural enterprises to intensify innovaƟon acƟvity. There is a problem in understanding the essence of moƟvaƟon, due to the mulƟplicity of approaches and methods of its study. The interpretaƟon of the concept of "moƟvaƟon" by Ukrainian and foreign scienƟsts is given. In modern condiƟons to ensure, the effecƟve funcƟoning of agricultural enterprises there is a need for innovaƟve acƟvity of employee. ScienƟsts' interpretaƟon of the concept of "innovaƟon" is presented. Based on the generalizaƟon of different views of scienƟsts, it is established that there is no single posiƟon on the definiƟon of "innovaƟon". In modern economics, the quesƟon remains: is innovaƟon the result of innovaƟon or is it a process of implemenƟng a new idea? Employees must form effecƟve management of agricultural enterprises based on the percepƟon of innovaƟons. The mechanism of employee moƟvaƟon of agricultural enterprises in the condiƟons of innovaƟve development is offered, which provides response to innovaƟve, economic, social, ecological changes, where the emphasis is made on increase of business acƟvity of workers, on their encouragement to introducƟon and fast percepƟon of innovaƟons. In modern condiƟons, the development of innovaƟve acƟviƟes of agricultural enterprises is on the verge of synthesis of scienƟfic knowledge and tangible assets. The modern management system of an economic enƟty should be based on the principle of development of its staff and the development of a mechanism for moƟvaƟng employees of agricultural enterprises to intensify innovaƟon. It was found that the percepƟon of innovaƟons by employees of the enterprise is their ability to implement innovaƟons, which is characterized by the Ɵme of implementaƟon. It is established that a well-built mechanism of staff moƟvaƟon contributes to the formaƟon of appropriate incenƟves and working condiƟons under which employees will work to achieve the goals of the enterprise. PosiƟve results of moƟvaƟonal measures to intensify innovaƟon in the agricultural enterprise will be achieved by encouraging employees to self-development to ensure their professional growth.


Objective To elucidate general characteristics of HIV/AIDS patients seeking care at Changsha Infectious Disease Hospital in an attempt to guide early diagnosis and treatment. Methods A retrospective analysis of 48 HIV/AIDS cases from April 2003 to June 2006 was completed by using SPSS statistical analysis. Results Among these patients, most of them were infected by sexually transmission route (75.0%). They were peasants, jobless and casual laborers, came from various districts of Hunan Province. The most common symptoms were fever (75.0%), weight loss (64.6%), cough(52.1%) skin rashes(43.8%), chronic diarrhea(37.5%), and lymphadenhypertrophia (37.5%); 14.6% cases had breathlessness and dyspneic respiration, 45.8% cases' white blood cells were lower than normal, 62.5% cases' chest X-ray were abnormal, 78.2% cases' CD4+ T lymphocytes were lower than 200/μl, and 85.4% cases had opportunistic infections(OIs). The most common OIs were thrush (52.1%), pulmonary infection (54.2%), fungal infected diarrhoea(14.6%), herpes(18.6%), and 16.7% patients were co-infected with pulmonary and extrapulmonary tuberculosis. Conclusion The majority of cases was general population and they had contracted HIV/AIDS sexually. Fever is the first presenting sign; weight loss, cough and diarrhea are the most common symptoms. Thrush and pulmonary infection are the most frequent OIs. Most cases' chest X-ray are abnormal and might been misdiagnosed as pulmonary infection. The most common pathogens of OIs are bacteria, fungus and virus. OIs are multi-organs effected and complicated.


A new list of localities of plant species found especially in old countryseats ("stinsen") in the Netherlands province of Friesland.


Fermentation of worts with high concentrations of fermentable sugars has become common practice in large clear beer breweries that use high gravity worts containing 16-18% (w/v) dissolved solids to obtain high alcohol contents. Normal and high gravity worts, ranging from 12 to 20% (w/v) initial dissolved solid contents were used in industrial opaque beer brewing and the biochemical characteristics of the brews were determined. Characteristics of the beers varied according to wort gravity. Decreases in dissolved solids and maltose contents were recorded during fermentation for all the brews. Higher residual dissolved solids, ranging from 6.5 to 11% (w/v), were recorded for the high gravity brews as compared to the normal brews, which had 3.5% (w/v) residual dissolved solids. An increase in ethanol levels was recorded during alcoholic fermentation for all the brews and the maximum ethanol levels, recorded after 72 h of fermentation for all the brews, were 3.5 and 6.0% (v/v) for the normal and high gravity beers, respectively. The optimal wort dissolved solids content recorded with regard to ethanol productivity was 18% (w/v). Increases in lactic acid and acetic acid levels were recorded for the brews, reaching maximum levels of 2.25 and 0.48 g/L, respectively, after 96 h of fermentation. No propionic acid was detected in any of the brews. Considering the quality of the beer, there was no settling observed for all the beers at 48 h of aging. Viscosity values, ranging from 100 to 190 mPa.s were higher than the expected levels for the industrial opaque beer (60-80 mPa.s) and values recorded for head were within the expected range for the industrial opaque beer (3 to 4).

 Key words: High gravity, opaque beer, dissolved solids, ethanol.


This paper describes the mechanisms through which parental occupational radiation exposure could affect children's health. It then goes on to review briefly some of the early work on this issue, studies based not on occupational exposures but on the Japanese atomic bomb survivors and on intrauterine x-ray exposure. Most of the discussion focuses on recent studies that have examined risks of childhood cancers and congenital malformations in the offspring of exposed workers, particularly some of the controversy engendered by recent cancer studies.


The aerometric results indicate significant differences between the annual means for SO2 and NO2 with the Seiberling school having the higher values. The questionnaire results indicate that the Seiberling children reported more wheezing in the chest, and shortness of breath than the Betty Jane children. Daily symptoms reported by the students indicate that the Seiberling children reported twice as many incidences of upper respiratory symptoms including rhinitis, cough, and sore throat. Baseline asymptomatic lung function testing did show that the ratio FEV1/FVC was significantly lower at the Seiberling school. For both schools there was a decrease in lung function during the symptomatic phase of an acute respiratory illness (AR!), and the tests further indicate that the ARIs in the Seiberling school were more severe and/or involved the small airways more so than the ARIs at the Betty Jane school. Recovery from the ARIs were not complete after nine days with the Seiberling children showing slower recovery than the Betty Jane children. On the basis of available aerometric information it is suggested that SO2 in combination with NO2 is primarily responsible for the reduction in lung function tests and the exacerbations seen in the children at the Seiberling school.


In the same way that the child shapes the adult, childhood literature stays with and affects the adult relationship with literature throughout a lifetime. Children's literature is as aesthetically and culturally important as adult literature, projecting patterns of language, narrative, and graphic imagery that are playfully simple and often rhythmic or repetitive—even musical— at the earliest stage. These patterns progress in sophistication through folkloric conventions to complex forms of literature and art, and I would like to suggest for this spectrum a theory of literary development that explains why literature precedes literacy in an aesthetic and emotional as well as a cognitive sense. Literacy is the experience of culture in literary forms; illiteracy is a deprivation of culture. That was not always the case. In most preliterate societies, culture was enjoyed and maintained by the oral tradition of storytelling, as well as by ritual art, dance, song, and ceremony. The material was made memorable by story elements and storytelling techniques. But the oral tradition was not unaffected by the literary. The story of "Beauty and the Beast," for instance, is an ancient folk narrative that was adapted as part of the Mahabharata and Jataka tales, returned from there to the oral tradition, rewritten as "Cupid and Psyche" by Aurelius in the second century, returned to the oral tradition, written down as a didactic fairy tale by French aristocratic women of the eighteenth century, returned again to the oral tradition, and broadly disseminated, most recently, in film and children's literature (Hearne, Beauty and the Beast 5). The interchange between oral and art forms is continuous, and the perpetually shifting versions of old stories in new editions resemble, in many ways, the patterns of oral variants. Since the nineteenth century, children's literature has passed on myth, folklore, fairy tales, and cultural motifs through a relatively new art form that bears some resemblance to the oral tradition in both content and


After the second place in RoboCup Rescue 2004, a new version of the mobile robot Kurt3D was developed in our groups during the last year [1]. The key innovation of this system lies in the capability for autonomous or operator-assisted 6D SLAM (simultaneous localization and mapping) and 3D map generation of natural scenes. Hence, Kurt3D already meets the basic requirement regarding urban search and rescue. For the rescue robot league competition, it is additionally configured with dedicated state-of-the-art equipment e.g. infrared camera and CO2–sensor. The robot and the operator station are rather compact and easy to set up. The operator uses a joystick as a remote control for the robot and can watch a live video of the scene where the robot drives. Data are transmitted via wireless LAN. A 3D laser scanner, which is mounted on an outdoor variant of Kurt3D, is used as the main sensor for map generation as well as for navigation and localization. The whole system has been used with a proven record of success for different tasks of map building, so that we are confident of managing the rescue robot league competition, too. R o b o C u p 2 0 0 5 R e s c u e R o b o t L e a g u e C o m p e t i t i o n O s a k a , J a p a n J u l y 1 3 – 1 9 , 2 0 0 5 w w w . r o b o c u p 2 0 0 5 . o r g


Sting nematode ( Belonolaimus longicaudatus ) is an important nematode pest of turfgrasses in the southeastern United States.  Three pesticides, including an insecticide (abamectin) and two fungicides (thiophanate-methyl and iprodione), were evaluated for efficacy against sting nematode in greenhouse and field trials.  In the greenhouse, maximum labeled rates of the three experimental pesticides were evaluated for nematicidal effects on sting nematode on creeping bentgrass and were compared to untreated control and the industry standard nematicide fenamiphos treatments.  In the greenhouse, all the pesticides demonstrated activity against sting nematode. A 2-yr field trial was conducted on a 'Jones Dwarf' bermudagrass putting green infested with sting nematode.  This trial evaluated treatment regimes that included the three experimental pesticides singly, in combination, and in rotation.  Regimes that included abamectin and/or thiophanate-methyl decreased numbers of sting nematode and improved root lengths compared to the untreated control in the second year.  Regimes that included abamectin had the greatest impact on turf percent green cover, increasing green cover compared to the untreated control on most evaluation dates in both years.


A rotating double-side sprinkle emission model is proposed to describe mechanism for the spiral arm formation of galaxies and various types of spiral patterns. The spiral galaxy can be treated as an ideal fluid system with a universal flat rotation curve; a rotating black hole is located at the center of the galaxy with rotating axis perpendicular to the galactic disc. Inside the black hole, the matter is transformed into new type of matter with anti-gravitational property and emitted by the black hole through two opposite directions in the galactic rotating plane similar to the lighthouse beams, it is then converted to non-gravitational matter. The new matter moves in straightly confined route for certain distance, and then it moves freely with its momentum combining the fluid rotation of the galaxy. The new matter will be transformed to hydrogens on its way of motion, increases the local hydrogen density, refuels the local stars and promotes young star formation, the luminosity of the area is temporarily enhanced, brighter than other areas, such enhanced luminosity area is what seen as the galactic bar and spiral arms. New formulas with one parameter and one variable are derived in three different cases. Different categories of theoretical spiral patterns have been produced and various real images of the spiral galaxies have been precisely simulated by the new formulas. This model seems a universal model and can be applied to most (if not all) spiral galaxies. Galaxies with special spiral patterns like Hoag's object and arms not meeting the end of galactic bars can be naturally explained by this model. This model is the first attempt to think the spiral arm formation with the hydrogen originated from inside of the galactic center to outside. The proposed mechanism of the hydrogen production seems highly speculative, but the result of the simulations is very satisfactory, this indicates that the idea for the hydrogens originated from inside the bar is a promising approach, may lead us to re-think about the property of the black holes and hope to serve as a trigger to promote the future research in this direction.


Some of the previous research showed that there was a significant effect between the Fama and French three factors model with the return. Some even found that there was no significant between the factors and the return. The objective of this research is to analyze the influence of Fama and French Three factors Model to the return of sharia mutual fund in Indonesia. The method of analysis used Autoregressive Distributed Lag (ARDL) to look the relation between the factors with the sharia mutual fund return in Indonesia in the long term and short term. The result showed that risk premium was significantly positive affect to the sharia mutual fund return in long term and short term. Size and book to market equity was not significant to the sharia mutual fund return in the long term and short term.


: In double porosity media, fluid could flow through the distributed micro-fractures at a larger scale as well as through the nanopores of the organic matrix at a smaller scale, while fluid mass could be transferred between them. Besides, the solid deformation acts as an important coupling term and leads to the two-way coupled process. However, these processes are not well presented in previous studies. In this work, a new coupled modeling approach was proposed for saturated double porosity media with strong permeability contrast. Specifically, the transversely isotropic equivalent fracture permeability is considered for the preferentially oriented micro-fractures at the micro-scale or meso-scale; while at the nano-scale, the non-Darcy flow and mass transfer equations are employed to consider the interaction between fluid particles and the solid pore wall. Finally, the stabilized finite element method is developed to investigate the settlement and pressure dissipation behaviors of the strip load problem.


ANOTHER academic year is nearly over. Looking back you can see how your class has progressed, how much they, and you, have achieved. There is still so much to be done before you can relax, and breathe! But stop, take a moment reflect on why it has been worthwhile, for good and bad: The year began with new children and fresh beginnings, getting to know one another, the year group assembly or show - which was a fantastic success, trips, an exhausting sport's day, parent's evening, reports, target setting, SATs… the list is endless.


Zika virus (ZIKV) is a re-emergent flavivirus that triggered a global health emergency from 2015 to 2017. ZIKV and other impactful flaviviruses, including dengue virus, lack the antiviral treatments and vaccines needed to diminish their threat to communities world-wide. This is in part due to gaps in our understanding of the flavivirus lifecycle; despite numerous investigations into flavivirus non-structural (NS) protein function. I hope to forge a deeper understanding of crucial NS protein functions and interactions throughout the ZIKV replication cycle. I will use alpaca-derived variable heavy-chain-only (VHH) antibody fragments, isolated from an alpaca immunized with ZIKV NS proteins, to perturb the replication cycle and therefore identify key NS protein epitopes used during replication. I individually purified NS1, NS2b, NS3, NS4b, NS5 for use in alpaca immunization, phage display panning, and enzyme-linked immunosorbent assays (ELISAs). From the alpaca peripheral blood I isolated RNA and amplified VHH genes, enriched for NS-protein binders with iterative phage display, and screened potential high binders via ELISA. I have isolated VHH sequences that interact with the ZIKV helicase, NS3, and the RNA-dependent RNA polymerase, NS5. I plan to purify each VHH and express them in ZIKA-permissive A549 cells as stable lines. Using purified VHH, I will analyze their binding ability in-vitro by ELISA and bio layer interferometry, and quantify in-vitro inhibition of NS3 protease and helicase activity for NS3 binders, and NS5 polymerase and methyltransferase activity. With the stable cells lines I will investigate each VHHs ability to impede ZIKV virus production and formation of replication complexes in infected cell lines.
 Support from training grant "Interactions at the Microbe-Host Interface" T32AI007472


Highway basic section serving level is an important content to analyze highway transit capacity.In this paper a maiden adoption of the grey clustering theories is introduced to analyze highway basic section serving level,and a multiple-objective model on analyzing the highway basic section serving level is set up based on grey clustering.Based on constructing whiteness matrix and whiteness functions the clustering weight coefficients and the clustering coefficients are calculated,and the comprehensive analysis result of the highway basic section serving level is obtained by the clustering coefficients.Finally a case study is carried out to verify the validity,objectivity and applicability of this model through calculated and analyzed practical data.The characteristics and applied scope of this model are also given which shows that the model mentioned above has the value to be referenced for analyzing the highway basic section serving level.


Objective:Understanding the resistance to drugs and phage typing of staphylococcus aureus(SA) isolated from the public places articles.Offering reference for public health surveillance.Methods:28 strains SA isolated from 1997 through 1998 in Chengdu public place articles were tested for antibiotic susceplibility(K-B method) and phage typing(commended by internation commission on staphylococcus phage typing).Results:The drug sensitivity results showed that the 28 strains SA were highly resistant rate to ampicillin(85 7%) and penicillin G(82 1%),and sensitive to oxacillin and ciprofloxacin,et al.Phage typing is most of Ⅰ groups.Conclusion:It is very important for public health surveillance department to pay more attention to drugs resistant strains of SA isolated from public place articles.


The introduction of tea, coffee, and chocolate into the western European diet during the mid 17th century revolutionized drinking habits. Chocolate and its fellow stimulating beverages gradually replaced traditional ale, beer, and hard cider as the breakfast beverages of choice in early America. Chocolate was fi rst introduced into colonial regions of northeastern North America in the late 17th century; having been introduced earlier in southeastern Spanish Florida (see Chapter 33 ). Chocolate often was used as an exotic and expensive medicine to nourish the sick, cure hangovers, or aid digestion. According to John Worlidge:


The purpose of this study is to analyze the characteristics of conflicts among the participants of housing reconstruction in Seoul Metropolitan Area. This study mainly relies on the content analysis of the articles of "The Reconstruction Weekly News". The results are as follows ; First, 370 samples are extracted from articles and classified into 22 categories with 74 items. Second, both categories and items are grouped by standardized frequency and intensity. Third, both the frequency and intensity of the City of Seoul significantly differ from Gyeonggi-do and the City of Incheon. Finally, the relationship between "Gu" of the City of Seoul, the municipal unit, and conflicts is examined with correspondence analysis. It is significant that this paper prepared a basis for further research, by introducing content analysis, thereby providing research methodology for a new analysis framework, and by creating a database with real case study data.


Salacia oblonga Wall, a medicinally important plant, belonging to the family Celastraceae, is a large woody climber distributed in southern India and Sri Lanka. In the present investigation, ethanol extracts of S. oblonga were prepared from aerial and root parts of the plant in the presence and absence of HCl and antibacterial activity was tested. Both aerial and root extracts exhibited pronounced activity against human pathogens. The MIC and MBC values ranged from 0.078-1.25 mg/ml and 0.156 -2.50 mg/ml, respectively. GC-MS profile of aerial and root extracts displayed the presence of 11 and 6 compounds. The present investigation demonstrated that ethanolic extracts of S. oblonga have potential antibacterial activity against human pathogens and could serve as a source for the development of new age antimicrobials.


Planting experiments during the past 7 years on the Dilldown Unit of the Delaware-Lehigh Experimental Forest in Pennsylvania and elsewhere in the scrub oak type have been aimed at finding methods for converting the scrub cover to more valuable timber types at least cost. Some sort of site preparation has been recognized from the beginning as essential to successful planting on much of the scrub oak land.


ABSTRACT In its resolution 1975 (2011), the United Nations security council opened the way for the provision of decisive support to the forces close to Alassane Ouattara to win the Ivorian power struggle. The deployed peacekeepers had a mandate "to protect civilians under imminent threat of physical violence." A second reason frequently given was the necessary enforcement of the popular will expressed during the presidential elections in 2010. Ever since a low-intensity civil war broke out in September 2002, the different military engagements by various international players were justified by (1) protection concerns and/or (2) the preservation of democratic achievements. In the end, the justification of intervention by the "protection of civilians" argument received a larger consensus than the democratic norm. This article compares changing justifications for intervention with real achievements.


It is our pleasure to introduce the new open access journal: Universal Journal of Civil Engineering. It publishes original research papers, review articles, communications, etc. Topics of publications in UJCE include, but are not limited to the following: structural engineering; construction engineering; transportation engineering; geotechnical engineering; earthquake engineering; coastal, harbour and offshore engineering; hydraulic engineering; environmental engineering; construction materials engineering; survey and geo-spatial engineering; municipal and urban engineering; solid mechanics.


Financial distress is a condition that occurs before a company goes bankrupt, so before that happens, the company needs to take actions such as good corporate governance practices. The purpose of this research is to determine the effect of the audit committee, ownership structure, and CEO on financial distress in trading, service, and investment companies listed on the Indonesia Stock Exchange for the period 2015-2018. The analysis technique used is logistic regression analysis. This type of research is quantitative by using a sample of 25 companies determined through a purposive sampling technique. The results showed that the frequency of audit committee meetings had a significant and positive impact on financial distress, and institutional ownership had a significant and negative impact on financial distress. While the other variables include: audit committee size, audit committee competence, audit committee independence, managerial ownership, family ownership, government ownership, foreign ownership, block holder ownership, and CEO's gender do not have a significant impact on financial distress. Implications of the results in this study are considering the frequency of audit committee meetings and the percentage of institutional ownership in predicting financial distress that can be used by companies and potential investors.


Summary: : The effectiveness of a lytic enzyme preparation (Elase*–Parke‐Davis) plus natamycin (Pimafucin–Gist‐Brocades) was compared to natamycin therapy alone in a controlled clinical trial involving 120 patients suffering from monilial vulvo‐vaginitis. The results indicate that addition of Elase to a natamycin treatment regimen increases the effectiveness of therapy both with respect to alleviation of symptoms and to eradication of the organism as determined by vaginal culture in patients with acute infection and in those in whom infection is complicated by pregnancy or diabetes.


CVN acts by binding with high affinity to the viral envelope glycoprotein thus inhibiting viral invasion and fusion of the virus particle to the target cell. Through molecular design and optimization a 5-amino acids flexible peptide(GGGGS)was linked to the N-terminus of CVN. SUMO-L5-CVN was expressed in the cytoplasm of E. coli BL21 in a soluble form by SUMO fusion expression system. After the optimization of expression conditions SUMO-L5-CVN was highly expressed in E. coli BL21 under the induction of IPTG (20℃ 24 h 0.5 mmol/L) . The fusion protein was expressed up to 30% of the total protein. The recombinant L5-CVN was purified to homogeneity by 2 rounds of Ni-NTA affinity chromatography and one round of SUMO protease cleavage. Nanomolar concentration of L5-CVN have a high affinity with the viral envelope glycoprotein gp120.


Abstract During the 1960s and 197Os, the native peoples of Canada's northern territories took action in response to concerns they had about the effects of development on their lands. In the 1980s, it became clear that the nature of environmental impacts in the Canadian North was changing- pollutants produced in far away places were entering and remaining in the Arctic food chain. Today, native peoples are seeking international cooperation to confront this threat to their environment and way of life.


Abstract : Contents: Description of the Computer Model, Correlation of Computer Model and Instrumented CFA, Computer Modeling Studies of CFA Interaction, and Approaches to CFA Design Based on the Computer Modeling Studies.


A three-dimensional electrostatic numerical tool has been developed to analyze spacecraft and Hall thruster plume interactions to evaluate spacecraft reliability under operation of the thruster in its designing phase. In the tool, Particle-In-Cell method is adopted to solve trajectories of beam and charge exchange ions under electrostatic field self-consistently. Particle tracking method is also adopted to compute the direct interactions such as the impingements of the plume ions onto the surface of a spacecraft to reduce numerical cost. In this paper, as a first step of the development, specifications of the code are described, and the fundamental functions such as determination of the distribution of the plume, production of charge-exchange ions, and electrostatic potential are introduced. Application analysis of the tool for an actual large-scale satellite, the estimation of the generating torque toward the center of mass of the spacecraft by the impingement of the plume ions, is also shown.


The objective of this paper is to examine the impact of leadership styles and organizational capabilities on performance in digital era, considering the mediating role of dynamic capabilities, organizational learning capabilities, knowledge management capabilities, and organizational innovation capabilities. This study tested the research model using structural equation modelling (SEM). A structured 40 items questionnaire exploring the relationship between leadership styles and organizational capabilities on performance was developed. Total of 400 valid questionnaires were collected from private hospitals and clinics in Thailand. The results showed that there are indirect effects of transformational leadership and IT capabilities on performance mediated by dynamic capabilities, organizational learning capabilities, knowledge management capabilities, and organizational innovation capabilities. This study contributes to theoretical and practical usage of the resource-based view in the domain of private healthcare service provider organizations by integrating leadership styles and organizational capabilities that include dynamic capabilities. This research also advance the usage of resource based view (RBV) and dynamic capabilities (DC) lenses to understand the mechanism how leadership styles and organizational capabilities enhance performance in private healthcare service provider context.


The common belief that the lightest supersymmetric particle (LSP) might be a neutralino, providing also the main Dark Matter (DM) component, calls for maximal detail in the study of the neutralino properties. Motivated by this, we consider the direct production of a single neutralino ˜


Different from traditional age estimation methods under classification or regression frameworks, this paper proposes a novel person-specific age estimation method under ranking framework. The basic idea is to consider the aging process as a personal age-ranked image sequences and extract the relevant information from this sequences. The estimation of age for an unknown face image is determined by first utilizing face recognition to find the persons in template sets who looks similar to the unseen person, then estimating the ranking order of the unseen person in corresponding person-specific image sequences, lastly mapping and fusing the rank order to its real age. Under this framework, our proposed system not only can estimate the correct the age orders of pairs of faces naturally but also can estimate the real age accurately. The proposed method has shown encouraging performance in the comparative experiments either as an age ranker or as an accurate age estimator and the experiment also proved the validity of the above assumption.


The ground, excited, and ionized states of free-base porphin (FBP) are reinvestigated by the SAC (symmetry-adapted cluster)/SAC-CI (configuration interaction) method. In particular, the Rydberg excited states, the valence−Rydberg mixing, and the effect of polarization d-functions are studied. The lowest Rydberg excited state would exist at around 5.5 eV with a weak intensity, but the valence−Rydberg mixing is small. The effects of both the Rydberg and polarization d-functions are relatively small for the excitation energies of the main peaks, whereas the polarization d-functions affect considerably the ionization spectrum.


It is not easy to find learning materials of interest quickly in the vast amount of online learning materials. The purpose of this study is to find students' interests according to their learning behaviors in the network and to recommend related video learning materials. For the students who do not leave an evaluation record in the learning platform, the association rule algorithm in data mining is used to find out the videos that students are interested in and recommend them. For the students who have evaluation records in the platform, we use the collaborative filtering algorithm based on items in machine learning, and use the Pearson correlation coefficient method to find highly similar video materials, and then recommend the learning materials they are interested in. The two methods are used in different situations, and all students in the learning platform can get recommendation. Through the application, our methods can reduce the data search time, improve the stickiness of the platform, solve the problem of information overload, and meet the personalized needs of the learners.


The coronary angiograms showed a severe focal restenosis of the  resorbable magnesium stent previously implanted in the right coronary artery. Coronary intravascular ultrasound did not show any significant intraluminal proliferation but demonstrated an impressive late stent recoil.


The article is devoted to the role of the inter-regional resource centers in the process of modernizing contemporary education. The author points out main principles and tasks of the inter-regional center work as well as its development perspectives in the system of education.


This research full paper characterizes the literature on academic initiatives to foster computational thinking and programming (CT&P) in Brazilian K-12 education. Context: Mapping and analyzing the diversity of experiences and studies that address CT&P in K-12 education can bring valuable data to researchers. This work delimits such study to the Brazilian scenario to allow a more in-depth view, given the Brazilian context. Previous surveys and systematic mapping studies present recent publications in major Brazilian computing journals and conferences. Although they offer important contributions, they do not comprehensively cover the Brazilian literature on CT&P in K-12 education, since they focus the search in the Brazilian Computer Society publications alone. Objective: This work proposes to characterize the literature on CT&P in K-12 education in Brazil. Results: through a systematic mapping study, we collected information on year, venue, type, K-12 education stage and modality, methodological contexts, and used tools and programming languages from 338 selected primary studies from 2001 until 2016. Conclusions: there is a significant increase in the number of Brazilian studies in the latest years, showing a growing interest on this research area as well as several trends and gaps to be addressed by both researchers and practitioners.


near Charlemont, and Mother of several Children, in January 1738-9 took her Labour Pains; but could not be delivered of her Child by several Women who attempted it. She remained in this Condition twelve Days ; the Child was judged to be dea after the third Day. Mary Donally, an illiterate Woman, ut eminent among the common People for extracting dead Birt s, being then called, tried also to deliver her in the common ay .


Aims : This clinical study is aimed at evaluating the effectiveness of exercise therapy in patients with temporomandibular joint disorder and comparing them with patients who take medications . Materials and Methods : 44 patients with temporomandibular joint disorder were divided into 2 groups, 22 patients were instructed to perform jaw exercises and the other 22 patients were given a non-steroidal anti-inflammatory drug and muscle relaxant. Clinical examination of joints and muscles, including pain, spasm, interincisal distance


Data on flows between employment unemployment and not in the labor force states are unavailable for Finland but some insights may be gained by the indirect and more traditional methods used in this paper. As these methods are not substitutes for analyses of flow data the papers results should be interpreted as suggestive. The paper introduces and estimates a simple model of both employment and labor force participation behavior of different demographic groups. The focus is on differences between the groups in the simultaneous cyclical fluctuations in these 2 variables and the pattern of unemployment variation of age-sex groups which arises from differences in participation and employment is examined. The paper utilizes the same apparatus to scrutinize long-run changes in the levels of age-specific unemployment rates discussing the impact of the institutional change brought about by the 1972 Employment Law. This exercise indicates that taking into account both employment and labor force participation variations is essential in order to understand the short-run cyclical movements in unemployment in the Finnish labor market as well as secular changes in unemployment that have occurred during the last 2 decades. Groups with higher than average unemployment rates respond to an increase in available jobs by increasing their participation thereby giving rise to the impression that it is very difficult to reduce their unemployment rates. This is expecially the case with teenagers and the old. Prior to 1972 females of nearly all ages belonged to the category displaying substantial fluctuations in participation but this no longer holds true from 1972. This is consistent with a reduced discouragement of women when demand slackens. It appears that the extension of the unemployment assistance system of 1972 may have reinforced the tendency towards a higher degree of permanency in female labor force attachment and that the extension did not only contribute to an increase in unemployment but also to an even greater increase in participation and consequently to an increase in employment as well. Too little is known about the interaction of other factors to make strong claims about which is (are) the "causa causans" of the simultaneous increase in employment and unemployment. Yet this suggests that the unemployment figures between the period before and after 1972 are not directly comparable or stated differently that the remarkable increase in the overall unemployment rate during the 1970s is due in part to the fact that some of the earlier hidden unemployment has become measurable. Also it is necessary to recognize that the reduced cyclical variation in participation of adult females may reflect changes in the composition of the female labor force. They are more educated and hold jobs requiring more skilled labor and permanent attachment to the labor market.


An easy synthesis of magnetic nanoparticles (Fe3O4) is described. Transmission electron microscopy (TEM), atomic force microscopy (AFM), dynamic light scattering (DLS) and X-ray diffraction (XRD) have been used to study the well dispersed and uniformly spherical nanoparticles. 5-Fluorouracil (5-FU) has been successfully loaded onto the nanoparticles and cytotoxicity studies were performed using a standard MTT assay. The results indicate that 5-fluorouracil-loaded iron nanoparticles are a more potent anticancer drugversus5-fluorouracil alone.


Designing applications for hybrid cloud has many features, including dynamic virtualization management and route switching. This makes it impossible to evaluate the query and hence the optimal distribution of data. In this paper, we formulate the main challenges of designing and simulation, offer installation for processing.


Thank you very much for reading sexual shakespeare forgery authorship portraiture. Maybe you have knowledge that, people have look hundreds times for their favorite readings like this sexual shakespeare forgery authorship portraiture, but end up in infectious downloads. Rather than enjoying a good book with a cup of coffee in the afternoon, instead they juggled with some harmful bugs inside their desktop computer.


We present a sparsity-based method for subwavelength coherent diffractive imaging: an algorithmic approach for reconstruction of subwavelength images from a single intensity measurement of their far-field diffraction pattern.


Electroencephalogram (EEG) neural activity recording has been widely used for diagnosing and monitoring epileptic patients. Ambulatory epileptic monitoring devices that can detect or even predict seizures play an important role for patients with intractable epilepsy. Though many EEG-based seizure detection algorithms have been proposed in the literature with high accuracy, their hardware implementations are constrained because of power consumption. Many commercial non-research EEG monitoring systems samples multiple electrodes at a relatively high rate and transmit the data either via a wire or wirelessly to an external signal processing unit. In this work, we studied how a reduced sampling precision affects the performance of our machine learning signal processing in seizure detection. To answer this question, we reduce the number of bits (precision) in an analog-to-digital converter (ADC) used in an EEG recorder. The outcome shows that the reduction of ADC precision down to 6-bit does not significantly reduce our convolutional neural network performance in detecting seizure onsets. As an indication of the performance, we achieved an area under the curve (AUC) more than 92% and above 96% on Freiburg Hospital and the Boston Children's Hospital-MIT seizure datasets, respectively. A possible reduction in ADC precision not only contribute to energy consumption reduction, particularly if the data has to be transmitted, but also offers an improved computational efficacy regarding memory requirement and circuit area.


One of the most significant sources of classical Turkish literature is poetry mecmua. The word "mecmua", which means "collected and assembled" in dictionaries, can be likened to today's


still rooted in fathering? What form does it take? How pervasive is it? Recent literature, working from within a framework of assumptions that allows for a critical dialogue between psychological and religious perspectives, has presented fresh insight into this problem. Bakan and Erikson, for example, converge upon a reexamination of the crucial importance of the father motif and suggest that several potent factors still reside in the father figure itself.' Alexander Mittscherlich, in an


ADIMEW (A ssessment of aged piping DI ssimilar ME tal W eld integrity) EC project aimed to quantify the accuracy of structural integrity procedures used in the European nuclear industry to ensure the safety of defect-containing dissimilar metal welds in aged PWR Class 1 piping. A 16 inch diameter DMW weld junction containing a large machined crack has been tested successfully under bending at 300°C to determine the actual behaviour of cracks close to the interface. The 16" Dissimilar Metal Weld mock-up (Pressurizer DMW type) has been manufactured according to nuclear industry specifications by FRAMATOME-ANP and the four point bending test has been performed by EDF. The fracture behaviour of the cracked pipe test is rather complex since the crack is not located where large yielding develops in the pipe, the crack surface is conical but its front is straight, the crack is loaded under mixed mode and is parallel to the interface between ferritic and austentic weld metal where strain concentration develops. Furthermore the welding process induces residual stresses only partially released by the post weld heat treatment. This paper presents ductile fracture analyses of the test and comparisons to experimental measurements. Framatome-ANP and ESI performed a J based analysis up to initiation and a ductile crack growth simulation using the Rice and Tracey criterion.Copyright © 2004 by ASME


The article examines the history of the creation of the Committee of Sea Excursions within the League of Renewal of Public Organizations. The role of the Committee of Sea Excursions among other Russian public military-patriotic associations formed after the defeat of the Russian Navy in the Russian-Japanese war of 1904-1905 is analyzed. It is noted that the promotion of naval knowledge among Russian students at the beginning of the twentieth century was one of the main tasks of the Committee of Sea Excursions. As a result of the active life position of representatives of the military and political elite after the Russian-Japanese war of 1904-1905 a domestic public organization appeared that helped to familiarize the population of the Russian Empire with the basics of domestic and foreign naval affairs.


The photorespiratory nitrogen cycle was initially thought to be a closed cyclic process. If this were true the loss of glutamate, glutamine, serine or glycine to other processes, such as protein synthesis or export from the leaves, would not be possible in a stoichiometric sense. However, recent studies with [15N]-labeled amino acids show that there are alternative sources of nitrogen for photorespiration, indicating that the nitrogen cycle is not a closed cyclic system. In addition recent work with 15NH4Cl and [15N]-glycine and a metabolically competent mitochondria system has shown that glutamate is synthesized in the mitochondria. Hence the glutamate dehydrogenase (GDH, EC 184.108.40.206) in mitochondria could also be active in the reassimilation of NH4. We would like to propose that one function of mitochondrial GDH is to synthesize glutamate from some of the NH4 released by photorespiration and that this glutamate represents a reserve for use in biosynthetic reactions.


In this study, aluminum alloy Al 6061-copper particulate metal matrix composites were prepared with three different volume fractions of reinforcement 75 im (1%, 2% and 3%) using stir casting route. The particles distribution, mechanical and physical properties are observed using SEM and XRD. Analysis is discussed on microstructure study and hardness; compression and density are explained in sight of mechanical and physical properties. Finally, it was observed from the results that the hardness, density and compression strength were increased by increasing in wt% of reinforcement.


With the development of electricity and electronic technology, micro-electronic technology and modern control theories, the frequency-modulation and speed-modulation technology have got extensive. application with its excellent characters. The article has deal with the specialties of the frequency-modulation and speed- modulation technology, selection of its devices and the application of the frequency-modulation and speed- modulation technology in building material industry.


This state-of-the-art handbook on intercultural communication, with its thirty-two chapters written by well-known figures, provide a comprehensive overview of the field to the audience. Surveyed topics include 1) deep association of important concepts, 2) related explanation of theoretical approaches, 3) overview of effective methods and methodologies, 4) recent research in different areas of implementation and application, and 5) note-worthy issues related to the assessment and evaluation of intercultural communication and competence. All in all, the handbook offers a thorough exploration of the relationship between intercultural communication and power as well as a contextual investigation of contrastive, imagological and ethical dimensions. The intended readership is wide and can include anyone with an interest in the field.


This article analyzes the implications of climate change on water resources. The point of departure is a previous research by the authors which takes into consideration the impacts of climate change on water resources and some scenarios, to offer a balance of national public policies in relation to integral water resources planning and management. To this end, official documents were analyzed, some events were attended, and experts were consulted to evaluate the degree of improvement the country has had in mitigation and adaptation of water resources sector to climate change. To achieve pertinent actions it is necessary to strengthen institutions and political will.


BACKGROUND: Glucagon-like Peptide-1 (GLP-1) is a naturally occurring peptide secreted by the L-cells of the small intestine. GLP-1 functions as an incretin and stimulates glucose-mediated insulin production by pancreatic β-cells. In this study, we demonstrate that Exendin-4/GLP-1 has a cognate receptor on human hepatocytes; and that Exendin-4 has a direct effect on the reduction of hepatic steatosis in the absence of insulin. RESULTS AND DISCUSSION: Both GLP-1R mRNA and protein were detected on primary human hepatocytes, and receptor was internalized in the presence of GLP-1. Exendin-4 increased the phosphorylation of PDK-1, AKT, and PKC-ζ, in HepG2 and HuH-7 cells. siRNA against GLP-1R abolished the effects on PDK-1 and PKC-ζ. Treatment with Exendin-4 quantitatively reduced triglyceride stores compared to controltreated cells. CONCLUSION: This is the first report that the G-protein coupled receptor (GPCR) GLP-1R is present on human hepatocytes. Furthermore, Exendin-4 appears to have in vitro, the same beneficial effects we have seen in our previously published in vivo study in ob/ob mice, directly reducing hepatocyte steatosis. Future use for human nonalcoholic fatty liver disease, either in combination with dietary manipulation or other pharmacotherapy, may be a significant advance in treatment of this common form of liver disease.


Objective To measure plasma atrial natriuretic peptide (ANP) in relation to maternal haemodynamics and body fluid balance in the early puerperium following uncomplicated pregnancy and pre‐eclampsia.