Correction for 'Highly efficient dual-state emission and two-photon absorption of novel naphthalimide functionalized cyanostilbene derivatives with finely tuned terminal alkoxyl groups' by Yingyong Ni et al., Mater. Chem. Front., 2022, 6, 3522–3530, https://doi.org/10.1039/D2QM00937D.


Scanning transmission electron microscopy (STEM) has found great opportunities in studying transformation heterogeneity at the nanoscale in energy storage materials, such as the chemical phase separation [1, 2], cation ordering and internal structures in electrode particles [4]. For example, our previous studies show that reduced particle size (< 100 nm) can effectively suppress the compositional heterogeneity in cathode particles during multivalent ion insertion [5]. Selected-area electron diffraction was employed to unravel the solid-solution phase formed in the cathode nanoparticles during phase transformation. Energy dispersive spectroscopy was used to visualize the composition non-uniformity in the cathode materials after electrochemical ion insertion, which is dependent on the particle size. Here, we build upon this earlier effort of ours to further apply scanning electron nanodiffraction, also known as four-dimensional (4D)-STEM, to study transformation heterogeneity in cathode nanoparticles While our previous studies focus on the composition non-uniformity in the cathode materials, in this work we study the structural heterogeneity, exemplified by the phase orientation and strain, in cathode nanoparticles. To map phase orientations in a transformation system, the conventional methods of template matching and correlation mapping [6] have limitations, as they are either designed for a single-phase system or consider multiple factors beyond phase orientation. To solve this problem, we define a parameter of "tetragonality" to describe the local distortion on the cathode structure induced by


Purpose – The main goal of this paper is to create a methodology for estimating public research and development (R&D) expenditures on Information and Communication Technologies (ICT) in the European Union (EU). The study further applies this methodology on business expenditures on R&D (BERD) data across all sectors and estimate ICT BERD within each of them. Then the study assesses the evolution of these expenditures in the context of the Digital Agenda for Europe (DAE) and its specific target to double them by 2020. Design/methodology/approach – The study assumes that the share of public ICT R&D expenditures in total public R&D expenditures is similar to the share of ICT R&D labour costs. The study bases its estimation on government budget appropriations or outlays on R&D (GBAORD). Findings – EU public ICT R&D expenditures grew steadily over the period 2004-2010 and in 2010 reached 5.9 billion. The study also estimates that the total EU ICT BERD in 2010 amounted to 15.8 billion. Regarding the DAE target a...


Most transport models for short-term strategic planning are required to be calibrated with current planning parameters and updated traffic data. There are basically two steps involved in transport model calibration, namely, trip matrix updating and network calibration. These two steps are carried out iteratively in the conventional approach and may not achieve a stable solution. This paper proposes a bilevel programming model that integrates the two steps of trip matrix updating and network calibration into one stage. A solution algorithm is developed on the basis of genetic algorithms. Numerical examples are presented to illustrate the performance of the proposed model and solution algorithm under various conditions where different source data are available.


In this paper, we devise a special $1$-error-correcting code that enables us to embed the graph product of an $N/\log N$-node hypercube and a $\log N$-node complete graph into in an $N$-node hypercube with constant load, dilation, and congestion. We apply the result to construct improved embeddings of trees and other structures in a hypercube, and to design more efficient and robust algorithms for reconfiguring a hypercube around random or worst-case faults. The result has also been used subsequently by others to show that the $N$-node hypercube can emulate all $N$-node planar graphs with constant slowdown.


The I/O access patterns of many parallel applications consist of accesses to a large number of small, noncontiguous pieces of data. If an application's I/O needs are met by making many small, distinct I/O requests, however, the I/O performance degrades drastically. To avoid this problem, MPI-IO allows users to access noncontiguous data with a single I/O function call, unlike in Unix I/O. In this paper, we explain how critical this feature of MPI-IO is for high performance and how it enables implementations to perform optimizations. An application can be written in many diierent ways with MPI-IO. We classify the diierent ways of expressing an application's I/O access pattern in MPI-IO into four levels, called level 0 through level 3. We demonstrate that, for applications with noncontiguous access patterns, the I/O performance improves signiicantly if users write the application such that it makes level-3 MPI-IO requests (noncontiguous, collective) rather than level-0 requests (Unix style). We describe how our MPI-IO implementation, ROMIO, delivers high performance for noncontiguous requests. We explain in detail the two key optimizations ROMIO performs: data sieving for noncontiguous requests from one process and collective I/O for noncontiguous requests from multiple processes. We describe how one can implement these optimizations portably on multiple machines and le systems, control their memory requirements, and also achieve high performance. We demonstrate the performance and portability with performance results for three applications|an astrophysics-application template (DIST3D), the NAS BTIO benchmark, and an un-structured code (UNSTRUC)|on ve diierent parallel machines: HP Exemplar, IBM SP, Intel Paragon, NEC SX-4, and SGI Origin2000. Preliminary versions of portions of this work were published in two conference papers 36, 37].


The kidneys carry out fundamental life-sustaining functions by removing waste substances, controlling salt and water balance, retaining substances vital to the body such as glucose and proteins, and maintaining blood pH balance [...].


Symmetry-breaking phenomena that often affect calculation of potentials for the linear ABA species along the antisymmetric-stretching coordinate are examined for the case of the ground state of the N3 radical using various coupled-cluster methods and molecular orbitals. The difficulties that are encountered when employing UHF-type approaches are found to be particularly striking. It is shown that the inconsistencies that arise when relying on a numerical differentiation can be overcome by exploiting the computed potentials in the Schrodinger equation for the nuclear motion. This approach yields reliable values for the vibrational levels even in the presence of singularities that plague the UHF-based potentials. The variety of the symmetry-breaking phenomena that occur for these systems, including the notoriously intricate BNB radical, are briefly discussed. © 2008 Wiley Periodicals, Inc. Int J Quantum Chem, 2008


Decision-making about innovative change in high-risk networks is exceptionally difficult because system failure may result in catastrophe. We adopt a historical method to compare the US and Soviet choices in their nuclear attack submarine programs between 1970 and 1996 and to surface their complex political, technological, and operational relations. One program achieved high reliability in the face of innovation while the other did not. Actor network theory (ANT) helps illuminate the interactions and resulting innovation paths and dependencies. We study how (i) open communication and power dispersion across high-risk networks influence system reliability, (ii) individuals spanning multiple groups within the network generate dominant coalitions, and (iii) strong safety advocates impact the network.


: 1203 Predictors of treatment and survival in hepatocellular carcinoma patients: A Bayesian parametric survival analysis Belaynew Taye, Paul Clark, Gunter Hartel, Elizabeth Powell, Patricia Valery The University Of Queensland, Brisbane, Australia, QIMR Berghofer Medical Research Institute, Brisbane, Australia, Mater Research Institute–University of Queensland, Brisbane, Australia, Department of Gastroenterology and Hepatology, Mater Hospitals Brisbane, Brisbane, Australia, Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Australia Background: Culturally and linguistically diverse communities face several challenges to receiving screening and curative treatment of hepatocellular carcinoma (HCC). We reported the predictors of receipt of treatment and survival in a cohort of patients diagnosed with HCC in Southeast Queensland. Methods: Data from 1651 HCC patients (147 migrants) followed between January 1, 2007, and December 31, 2016 were analyzed using chi-square statistic to test for the association between socioeconomic variables and receipt of treatment. Bayesian Weibull Accelerated Failure Time regression was used to identify predictors of time to death, and we reported time ratios. Results: Receipt of surgical resection for HCC was associated with non-metropolitan residence (P1⁄40.02), non-English language (P<0.001), country of origin (P<0.001), and hepatitis B virus etiology (P<0.001). The median survival time after HCC diagnosis was 9.0 months (interquartile range 2.0–24.0). The strongest predictors of survival were undifferentiated tumor at presentation (time ratio (TR)1⁄40.30, 95% credible interval (CrI) 0.23–0.39), age 70 years (TR1⁄40.42, 95%CrI 0.34–0.53), living in a remote area (TR1⁄40.67, 95%CrI 0.55–0.80), and presence of 1 comorbidity (TR1⁄40.69 95%CrI 0.54–0.90). Conclusions: Improving access to HCC surveillance and uptake of timely curative treatment for persons living in remote areas and having socioeconomic disadvantage may help patients present to clinic with early stage tumor and provide better survival. Key messages: Remoteness of residence is associated with late presentation, low rate of receipt of treatment and predicts survival of patients with HCC. the incidence of HBV infection, liver cirrhosis, hepatocellular carcinoma, and HBV-related mortality in four groups of people according to their country of birth. Results: The number of chronic HBV cases will remain similar, and HBV-related morbidity and mortality will increase if the baseline approach is followed to 2030. Implementing an optimistic treatment scale-up could reduce the number of new cases of liver cirrhosis (30% in European-born, and 40% in Asia-Pacific-born) by 2030. Following the optimistic scale-up approach, the incidence of HCC decreased by 30% and a 15%-25% reduction in HCC-related mortality could be achieved in the four population subgroups by 2030. Conclusions: Following the current antiviral treatment coverage, HBV elimination targets in migrants may not be achieved. A rapid treatment scale-up approach reduces HBV incidence, liver cirrhosis and HCC. Key messages: Targeted antiviral treatment for migrants with HBV using rapid scale-up reduces HBV-related disease and mortality and contributes to achievement of national elimination targets.


Existing research on occupational qualification system has been centered on certification effects on labor market performances, or on the processes and consequences associated with the introduction of an individual professional certificate. However, how the occupational qualification system as a who...


The Thelma Field is the most southerly of three fields located in Block 16/17 of the UK sector of the South Viking Graben, and is operated by CNR International (U.K.) Ltd. The Thelma Field comprises two submarine fans, the northern Thelma Fan and the southern Southeast Thelma (SET) Fan, revealed by subsurface mapping. The two fans consist of both Upper Jurassic Brae (Upper Oxfordian - Lower Volgian) and Sand-Shale (Middle Volgian) Members of the Kimmeridge Clay Formation. The two fan depocentres are separated by a low net: gross Central Region High, which was overtopped or diverted around by turbidity currents that formed the younger Sand-Shale Member. The Brae Member contains conglomerates, pebbly sandstones, sandstones and thin-bedded turbidites of deep water association. Seismic data are generally poor in this area, and conceptual and reservoir geological modelling are primarily based on oilfield core, wireline logs and dynamic reservoir data. Three conceptual models were created to propose geological scenarios for field development: Concept A has the SET Fan fed independently from the southwest; Concept B has the SET Fan fed as an extension of the Thelma Fan from the north; and Concept C has an SET Fan fed by bypass across the Central Region High. Each concept has different implications for fan connectivity. Using detailed core description from the Thelma Field, state-of-the-art deep-water facies analysis, a new facies scheme, known deep-water facies associations on the modern sea floor and outcrop analogues, we test the conceptual models to validate the geology. The large scale organisation of the architectural elements of the Brae and Sand-Shale Members are not well understood. By reviewing coarse-grained deep-water processes and the rock fabrics that they produce as a framework for rock property distribution in coarse-grained deep-water systems, we aim to investigate their architectural style. We recognise a series of facies associations from detailed facies descriptions of the cored intervals, and by distilling these sedimentological trends, ascribe the associations to uncored intervals and use these as a basis for correlation and reservoir modelling in the Thelma-SET area. The model is built from cored sedimentary facies, and facies associations recognisable on core-calibrated well logs, and then matched with dynamic well data, to test conceptual models. By combining the conceptual geological models with dynamic well testing of reservoir behaviour, we have a more robust understanding of the two fields. Thelma is a higher energy system, with strong aquifer support facilitated by channelised reservoir architecture and poor lateral shale continuity, whereas SET is a lower energy system with poor aquifer support due to persistent lateral continuity of shale caps on sandstone lobes, and with no deep channelling recognised.


The invention discloses a fancy yarn and a spinning method of the fancy yarn. The fancy yarn is a cotton/viscoce blended yarn, and comprises a base yarn and first nubs, the longitudinal line density of the fancy yarn is regularly changed in a segment of the one-rotor circumference, at least two sections of first nubs uniformly exist, a section of second nub with the length and the diameter both being respectively smaller than those of the first nubs is arranged in the middle position of the two adjacent sections of the first nubs, the first nubs and the second nub are fluffier than a yarn body of the base yarn and have smaller twist degree, the fancy yarn is spun through continuously applying external force in a certain length on the path from the entering point of a single-fiber flow into a rotor before merging and agglomeration, and the external force applying mode refers to positive-pressure or negative-pressure additional airflow exertion at a seam part of the rotor. The fancy yarn provided by the invention has the advantages that the styles are unique, the types of rotor spinning products are enriched, and higher practicability and higher economic values are realized.


This article aims at exposing about the risks which might occur when the high concentration of ownership and control combines with elements such as oligarchic tendencies, informal networks, the most often invisible, between oligarchs, politicians and/or former nomenklatura, lack of effective implementation of regulations in the competition field, and, last, but not least, the size of the market and its recent political and economic developments. In the vision of scholars, views adopted by the European Commission in its recent 'Media Pluralism Monitor' (2009), the 'structural pluralism' (pluralism of ownership and control) plays a role in shaping the whole concept of pluralism, along with other identified forms of pluralism: media types and genres, political viewpoints, cultural expression and local and regional interests. Written form a risk perspective, the article aims at analyzing some of the factors which might be relevant, in relation to structural pluralism, based on case studies which are generously offered by the recent developments in the country: the political affiliation of media owners, the judicial investigations some of them have been subject of, the increasing dominance of certain players, the openness of the market versus the state monopoly in certain fields (e.g. the nationwide terrestrial TV licences). The emergence of different factors and the different ways how they interact might transform an apparently 'beneficent' consolidation of the media (from the liberal perspective) into a danger for democracy.


Recently there is an increasing interest in the use of artificial intelligence for on-board processing as indicated by the latest space missions, which cannot be satisfied by existing low-performance space-qualified processors. Although COTS AI accelerators can provide the required performance, they are not designed to meet space requirements. In this work, we co-design a low-cost SIMD micro-architecture integrated in a space qualified processor, which can significantly increase its performance. Our solution has no impact on the processor's 100 MHz frequency and consumes minimal area thanks to its innovative design compared to conventional vector micro-architectures. For the minimum configuration of our baseline space processor, our results indicate a performance boost of up to 9.3× for commonly used AI-related and image processing algorithms and 5.5× faster for a complex, space-relevant inference application with just 30% area increase.


Over the 1990s hedge funds have emerged as major players in financial markets. These funds have taken very large positions in particular markets, with some funds apparently being prepared to use high leverage to do so. This has led to concerns that hedge funds are contributing to financial instability and impairing the efficient operation of markets, although, on the other hand, there are also those who point to the greater depth of markets that has resulted from the higher turnover that hedge funds generate. Criticisms of the undue influence that hedge funds can have on markets have been around for some time, but the recent event which brought the issue to centre stage was the threatened collapse of Long-Term Capital Management. This incident not only seemingly led the US Federal Reserve to widen the "too important to fail" test to include a hedge fund, but brought home to the authorities the risks that some funds posed to the stability of the financial system.


As part of the business globalization phenomena, executives are called upon, more frequently than before, to consider regionally-focused organizational structures, such as regional headquarters, and to determine their location. However, academic literature, as of now, has not placed much emphasis on the subject of regional headquarters and their study has only recently become an emerging area of interest in the field of international business. This paper presents a taxonomy and analysis of literature regarding regional headquarters of multinational corporations, with the purpose of identifying limitations of current literature, as a basis for future research.


STREAMS offers a set of driver development and functional framework based on layered modules. Its programming interface is based on message, which makes it convenient to buffer management, flow control, and priority based message schedule strategy. It supports varied kind of service, from complete network protocol to single device driver. Since document on STREAMS prdctical development is scarce, based on the faundation to have developed several this kind of drivors, This article introduces its core data structures and associated routines, and further give some development recommend summarized from practical project.


This article draws on a major research project en- titled "Passing through Universidad Distrital Francisco Jose de Caldas (UDFJC): Agreements and disagree- ments. A look at the daily life of students: Those who stay and those who leave". This project was developed by the Institute of Educational Studies and Research (IESR). The study's main purpose is to describe and comprehend sociocultural situations associated to university students' academic difficulties and dropout rates at UDFJC. This was achieved by analyzing univer - sity life. The study contributes with critical and reflex - ive elements aimed at establishing coherent, participative and articulated actions to promote the integral human development of the academic community. This research study was conducted by an interdisci- plinary faculty team. Students' difficulties and ruptures that occur in university life affecting dropout rates were obtained via students' own voices and narratives.


We studied the magnetic and optical properties of antiferromagnetic zinc blende MnS layers with thicknesses of 1.8 nm and 8.3 nm, which were grown between ZnSe cladding layers by molecular beam epitaxy on a (100)-GaAs substrate. The paramagnetic to antiferromagnetic phase transition has been studied by optical and SQUID-measurements. The yellow emission band of the internal manganese 3d-states undergoes a significant blue shift below the magnetic phase transition, which is caused by the total spin orientation in this magnetic phase. It was found that the phase transition itself can be influenced by an external magnetic field in case of the 1.8 nm sample but remains unchanged for the 8.3 nm sample. SQUID-measurements confirm the results of the optical techniques and reveal moreover the occurrence of a field induced ferromagnetic phase transition in case of the thinner sample. (© 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)


The international publication Datapro has revealed that competition appears to be thriving in New Zealand. There are few areas where consumers do not have choice and the benefits are quite obvious to consumers.


An overview of the compositional approaches taken during the construction of my PhD Visual music portfolio. Examines links between sound and image and creative technological approaches influenced by visual media and music.


In this article we prove two results concerning the motivic Milnor fibres Sǫ(f) of symbol ǫ ∈ {±1, <,>} associated to a map germ f : (Rn, 0) → (R, 0), as defined by G. Comte and G. Fichou in [5]. Firstly, we prove that if f, g : (R, 0) → (R, 0) are arc-analytically equivalent germs of Nash functions ([4, Definition 7.1]) then the virtual Poincaré polynomial of the motivic Milnor fibres Sǫ(f) and Sǫ(g) are equal. This extends and provides a new proof of the result [7, Theorem 4.9]. Secondly, let T ⊂ Rm be a real algebraic set and f : T × (Rn, 0) → R a polynomial function of polynomial map germs such that f(t, 0) = 0 for any t ∈ T . Then we prove that there exists a locally finite real analytic stratification S of T such that if S ∈ S is a stratum then ft ∼a ft′ are arc-analytically equivalent, for any t, t′ ∈ S. Furthermore, if T is compact then the stratification S can be taken to be finite. These two results imply in particular that the virtual Poincaré polynomials of the respective zeta functions are equal i.e β(Sǫ(ft)) = β(S ǫ(ft′)). Classification: 14-XX


This paper investigates the sliding mode control (SMC) problem for discrete-time networked control systems (NCSs) subject to time delay and data packet loss. Firstly, a sliding surface is constructed and the sliding mode controller is developed for the considered NCSs, which is designed later based on the constant rate reaching law approach such that the state trajectory of the system can be driven onto the pre-designed sliding mode surface and maintain there for subsequent time. Next, the networked predictive control (NPC) scheme is introduced and proved to be feasible in the active compensation for the network-induced time delay and data packet loss. Finally, an example is given to demonstrate the effectiveness of the proposed networked predictive SMC strategy for the considered NCSs.


It took using aerial photograph existence quality blemish to produce scale 1∶10000 digital orthophoto mapping as an example,the methods for fiducial mark lack definition,aerial photograph not been well flattened,image middle tone differ more big and image contrast and clear not enough been studied in the article. The author wishes that those can help other who have or will face the same problem.


We determined if all‐night exposure to 60 Hz magnetic fields at an intensity well within the upper range of occupational exposures (resultant intensity=127.3 microTesla [μT]) resulted in suppression of melatonin or its major metabolite 6‐hydroxymelatonin‐sulfate (6‐OHMS) in the first‐void morning urine of 24 healthy male volunteers. Measures collected after continuous and intermittent magnetic field exposure test conditions were compared to similar measures collected after an equivalent no‐exposure control condition. Urinary concentrations of melatonin and 6‐OHMS did not differ as a function of type of magnetic field exposure, nor did they differ between field exposure and control conditions. These results demonstrate that the nocturnal secretion and metabolism of melatonin are not altered in humans by field exposure at an intensity over 600 times higher than that typically encountered in the home.


The 1970s were an exciting time for the development and attention given to estimating human health risk for environmental and occupational exposures. In the 1960s much attention and concern was given to the epidemiological studies by Richard Doll on cigarette smoking and lung cancer, Irving Selikoff's studies of asbestos workers, Rachel Carson's book Silent Spring, and the adverse health effects of ionizing radiation observed by the Atomic Bomb Causality Commission in Hiroshima. This all helped lead to the creation of the Environmental Protection Agency (EPA) as well as the National Institute of Environmental Health Sciences (NIEHS) in 1966 and its National Toxicology Program (NTP) in 1976. Also at the international level, the International Agency for Research on Cancer (IARC) of the World Health Organization began their monograph series of the evaluation of cancer risks to humans in 1972. There have been over 100 of these important monographs that include for each topic evaluations of sources of the material under study along with evaluations of the toxicology, epidemiology, and mechanistic evaluations. The monographs, however, do not attempt to quantify the cancer risk. The EPA's Integrated Risk Information System (IRIS) reports do provide quantitative estimates of risk. There are now over 900 substances listed in the IRIS directory of reports. There are now about 600 NTP reports from NIEHS. These reports are the result of rodent tests of various chemicals. The typical study consists of 300 animals (150 mice, 150 rats) exposed to a maximum tolerated dose (MTD), 1/2 the MTD, and a control group exposed for 2 years with thus 50 animals per dose group. What was of particular importance is how one analyzes the rodent data and how to translate any positive rodent effects to human risk particularly to low doses for setting environmental and occupational exposure limits. The major risk assessment challenges in the 1970s were highto low-dose extrapolation and "mouse to man" extrapolation. The primary focus was on cancer effects since they were of greatest concern from a public health viewpoint. Back in the 1950s the idea of a safety factor approach to set acceptable limits on exposures was developed. This was especially of importance for food additive policies. The use of a factor of 100 applied to the highest "no effect level" in a study was used. A factor of 500 was applied if instead one used the "lowest positive effect level." The use of 100 was based on the idea that a factor of 10 when extrapolating from animals to humans and incorporated another factor of 10 to account for differential sensitivities within the human population. Weil proposed using a factor of 5000 from the lowest positive effect dose because of uncertainties in animal to man extrapolation. Instead of a simple safety factor approach, the log-probit method of Mantel and Bryan in 1961 attempted to fit a function (the probit) to the observed dose–response data and then to estimate effects at given low doses. This seemed appropriate for cancer since it was not accepted that thresholds exist for carcinogen exposures. This helped to set off a lot of varied activity in selecting appropriate dose–response functions for the purpose of estimating low-dose cancer effects for regulatory exposure limits. The logit function has provided similar fits; however, the choice of dose–response function can make a considerable difference at very low doses. For extrapolation purposes, carcinogenesis data consisted of 2 types. The usual form gives lifetime incidences at various doses for estimation of a dose incidence curve and its associated error probabilities (eg, probit, logit, one-hit). The second type of dose–response modeling is time-to-occurrence as a function of exposed dose. The time-to-occurrence would typically be time of death due to the cancer of interest or time of first appearance of the particular tumor of interest. This brought forward competing distributions. Albert and Altshuler considered the lognormal distribution. The other popular choice was the Weibull distribution (Pike and Peto et al).


National assets are publicly owned assets from property rights.The management on national assets is very weak in our country, it exists a series of problems,which root in the weakness of the management mode on national assets.therefore, it is necessary to learn the advanced management methods on national assets of western countries. Then we can find the new management mode which is suit to our country.


The report presents the main results of a major empirical analysis of the correlation between two of the most popular value parameters – economic value added (EVA) and the market value added (MVA), reviewed as convenient appraisal models of the fundamental and market company value, respectively. The study comprises 168 Bulgarian companies, listed on the Bulgarian Stock Exchange for the period from 2005 to 2008.


Based on Law Number 24 of 2011, a state program was established to provide social protection and welfare for everyone, one of which is health insurance by the Social Insurance Administration Organization (BPJS). In its implementation, several important evaluations are needed. One that requires accurate evaluation is claim frequency and claim severity in determining premiums and reserved funds. This thesis provides one form of a method for selecting the distribution of claim frequency and claim severity. The data used in this study was taken from BPJS Health in the City of Tangerang in 2017. The distribution of opportunities chosen had been adjusted to the participant's claim data and parameter estimated using the Maximum Likelihood Estimation method. The chi-square test was used to check the goodness of fit for claim frequency distributions whereas the Anderson Darling tests were applied to claim severity distributions. The results of the chi-square test and the Anderson-Darling test showed that the model that matched the claim frequency distribution was the Z12M–NBGE distribution while the model that matched the claim severity was lognormal. The Z12M–NBGE distribution and the lognormal formed the aggregate loss distribution using the Monte Carlo method. Furthermore, the simulation results were obtained to the measurement of the Value in Risk (VaR) and Shortfall Expectations (ES). So, the Monte Carlo method is simple to implement the aggregate loss distributions and can easily handle various risks with dependency.


and postcardiac rhythm strips; and advanced cardiovascular life support–certified surgical personnel. Although MMS resulted in no adverse effects, our patient was not pacemaker dependent. Approximately 5% to 10% of patients with implanted cardiac pacemakers are dependent on their devices for maintaining adequate heart rhythm. Electromagnetic interference in a pacemaker-dependent patient is potentially life threatening, whereas in a nondependent patient, it is likely that pacemaker malfunction would result in less-acute consequences.


THE PALM VALLEY structure is located about 75 miles southwest of Alice Springs, Northern Territory, and is a large gentle structure located in the north central part of the Amadeus Basin. It was discovered gas productive by the drilling of the Palm Valley No. 1 well completed May 20, 1965. The No. 1 well was drilled to a total depth of 6,658 feet and produced gas from the lower Stairway, Horn Valley and upper Pacoota formations of Ordovician Age. Since completion of the No. 1 well, two additional wells have penetrated the Palm Valley structure. Because the producing characteristics of the three wells vary considerably, an extensive pressure transient testing program has been carried out in order to estimate reservoir characteristics and to estimate the range of the potential reserve for this structure. The transient pressure tests when analyzed by the most modern techniques accepted by industry indicate widely varying storage capabilities and in some instances yield results which are not easily correlated with geological interpretations. The purpose of this paper is to present the theory and the results of the transient tests performed to date and to discuss the possible meaning of the pressure behavior.


The development of country tourism has been rising promptly since 2000.Although many country tourism projects have been constructed in different areas,the current development mode of country tourism can not meet the needs in new era.Therefore,from the view of industrial chain and the analysis on dynamic mechanism of the sustainable development,we are proposing a new development mode——multi-industry linkage development mode of country tourism.The new mode is based on the analysis of existing tourism resource and market in Shuiji town,and the integration and optimization of industrial elements in and between different areas,aiming to consolidate the foundation of country tourism development and to promote the further economic development of country tourism in Shuiji town.


The patient presented in this case report had an incomplete abortion after dilatation, curettage and tubal fulguration, despite postoperative radiologic evidence of tubal occlusion. The pregnancy evidently either survived the fulguration to abort later or was intrauterine and missed by the curettage.


The excavation of two of the famous playhouses of Tudor London, the Rose and the Globe, provided the first concrete evidence for the size, layout and development of these playhouses, now presented in detail for the first time in 400 years. The remains of the Rose playhouse were revealed 20 years ago and aroused great interest throughout the world, far beyond the normal confines of archaeological discovery. To the scholarly world the Rose was famous through the survival of day-to-day accounts written by its owner Phillip Henslowe, and to the theatre world as the stage where many of Marlowe's plays were first performed; the investigations brought this history to life. The excavation of a smaller part of the Globe, the home of many of Shakespeare's plays, revealed less detail but was an important emotional, as well as archaeological discovery. This archaeological report will appeal to a wider audience of those interested in the history and development of the theatre. The hundreds of individual elements found in the excavations, together with newly researched documentary sources, have been fully integrated into a narrative description and thematic discussions on every aspect of the playhouses, the plays and the audiences. The volume is lavishly illustrated with contemporary views, reconstructions and detailed drawings and photographs of structures and finds from the excavations.


The problem of computing the closed loop transfer function of a linear system represented by its block diagram or by its flow graph is of importance in CAD programs designed for the analysis of linear systems. Mason's rule (1953) is one of the available techniques to perform such calculations, but it requires searching into the graph for different paths and loops and becomes slow as system complexity increases. In this paper, a method is developed to efficiently compute the closed loop transfer function and intermediate transfer functions of a linear system. >


Repeated point contact loading has been used to investigate the deformation and fracture of single-crystal magnesium oxide subjected to cyclic loading by softer metallic cones at room temperature. The results of the investigation clearly indicate that MgO is susceptible to cyclic fatigue. An explanation for the mechanical cyclic fatigue effect is proposed.


This Paper presents effective AI calculations and procedures utilized in removing illness and therapy related sentences from short content distributed in clinical papers. The fundamental target of this work is to show what Natural Language Processing (NLP) and AI procedures utilized for critical of data and what characterization calculations are reasonable for recognizing and grouping pertinent clinical data in short content. In this paper additionally presents medical services that seek therapy and avoidance to avoid infection, disease, injury in humans. This has made the space familiar with some of the undertakings of medical services data, clinical administration, patient wellbeing data, and further proposed processes can be organized on a better clinical option by coordinating with any clinical administration framework and bio can be mined naturally in medical data. Ongoing years have seen broad selection of AI (ML)/deep learning (DL) strategies because of their predominant exhibition for an assortment of medical services applications going from the expectation of heart failure from heart signs to PC supported determination utilizing multiple-era clinical pictures. Despite the amazing presentation of machine learning, there are as yet waiting questions in regards to the vigor of machine learning in medical services settings (which is customarily considered very testing because of the bunch security and protection issues included), particularly considering ongoing outcomes that have shown that machine learning are helpless against ill-disposed assaults. The paper indicate that an outline of different application regions in medical services that influence such strategies from security and protection perspective and present related difficulties. What's more, we present likely strategies to guarantee secure and protection saving ML for medical care applications. At last, we give knowledge into the ebb and flow research difficulties and promising bearings for future examination. AI assumes a fundamental part in medical services field and is by and large progressively applied to medical services, including clinical picture division, picture enrollment, multimodal picture combination, PC supported analysis, picture guided treatment, picture comment, and picture information base recovery, where disappointment could be deadly. The motivation behind this extraordinary issue is to progress logical exploration in the expansive field of AI in medical care, with centers around hypothesis, applications, late difficulties, and bleeding edge methods. Acquiring information and noteworthy experiences from perplexing, high-dimensional and heterogeneous biomedical information stays a vital test in changing medical care. Different sorts of information have been arising in present day biomedical examination, including electronic wellbeing records, imaging,-omics, sensor information and text, which are mind boggling, heterogeneous, ineffectively clarified and by and large unstructured. Conventional information mining and factual learning approaches normally need to initially perform highlight designing to acquire successful and more powerful highlights from those information, and afterward construct expectation or bunching models on top of them. There are loads of difficulties on the two stages in a situation of muddled information and lacking of adequate space information.


Performance targets are widely used in the public sector to align the goals of public managers and employees with policies passed by elected ocials. In a number of countries, especially in Western Europe and among the English-speaking parliamentary democracies around the world, governments have moved the bulk of their operations into executive agencies that are led by chief executives on performance contracts. Often, the performance targets under which the chief executives of these agencies operate are negotiated between them and their overseeing minister. We outline a theoretical argument based on chief executive background and goals to suggest that insiders - in this case, chief executives with a civil service background - will be more likely than civil service outsiders to choose more easily achievable targets, i.e. targets within the control of their agency. We test this hypothesis using data on most British executive agencies from 1992/93 to 2010/11. We operationalize target diculty by coding each


David Hicks is an Associate Professor with the Institute for Electronic Systems at Aalborg University. Previously he has served as Department Head for the Department of Computer Science and Engineering at Aalborg University's Esbjerg campus. He has also held positions in international research labs in the US as well as Europe, and spent time as a senior researcher in the software industry. He has served in a variety of capacities in the hypertext community including Vice Chair for SIGWEB.


THE Michigan Department of Administration, a central management agency which is responsible for most of the "housekeeping" activities of the state government, was created and began to function in 1948. In commentaries on similar central management agencies and their work, references to the political environment of state government have been rare. The advocates of agencies like the Michigan department, together with the commentators on those which have been created, have seemed to assume that such agencies function in a "pure" administrative atmosphere, uncontaminated by political or policy considerations. This assumption is certainly not justified in the case of the Michigan department. Although it is generally conceded, even by its severest critics, that the department has made considerable advances in the technical management aspects of state housekeeping activities, the department has been inextricably enmeshed in the complexities of "politics" in Michigan. Political forces presided over the birth of the department and have influenced it continuously since. Its future may well depend on its acceptability to dominant political groups, and their decision may not necessarily be based on an objective evaluation of its technical record. Consequently, its "political" life has perhaps


Thermo-electropulsing rolling (TER) process, which combined the electropulsing treatment with the conventional warm rolling process (WR), was applied to manufacture AZ31 magnesium alloy strips in the current study. Influences of TER process and WR process on microstructure and mechanical properties of AZ31 Mg alloy were studied. TER process was found to induce and accelerate the dynamic recrystallization (DRX) behavior of the samples at a relatively low temperature within a short time. Besides, TER process could obtain samples with better mechanical properties than that of WR process.


Frequency analysis is a useful tool for flood risk assessment,but the definition and calculation of return periods and design values in a multivariate framework are difficult tasks. In this paper,by constructing the joint distribution of flood duration,peak discharge and volume,we introduced the definitions of multivariate"OR","AND"and secondary return periods and discuss their differences in identifying the safe and dangerous regions in a critical level. The rationality and reliability of information provided from them in flood risk management and engineering design were then analyzed,respectively. The traditional"OR-AND"approach in multivariate return periods definition is limited in the identification of safe and dangerous regions,while the secondary return period based on the Kendall measure would be more rational. Consequently,mistakes in the recognition of safe and dangerous event can be avoided by the use of second return period,which,obviously,is better for the flood risk management. For a given second return period,the combination of flood duration,peak discharge and volume design values calculated from the most-likely approach,may have an advantage to meet the requirement that with low cost to bear greater risks in engineering design. Furthermore,the information provided from multivariate design values would be more considerate and reliable than the univariate ones.


The reaction of S-(phenyl benzothiazolyl-2)phosphorodichloridothioate/phosphorodichloridodithioate with 2 mol of phenol/4-chlorophenol/4-nitrophenol in the presence of stoichiometric amounts of triethylamine in dry THF/CH2Cl2 has afforded a series of the corresponding organophosphate phenoxy derivatives (1a, 1b, 2a, 2b, and 3a, 3b). Plausible structures have been proposed on the basis of elemental analysis, IR, 1H NMR, 31P NMR, and mass spectral studies. The antibacterial activity of these organophosphate phenoxy derivatives has been evaluated against pathogenic bacteria Staphylococcus aureus (+ve) and Escherichia coli (−ve). The antifungal activity of these organophosphate phenoxy derivatives has been evaluated against pathogenic fungi Aspergillus niger and Fusarium oxysporium. The results indicate that organophosphate phenoxy derivatives are found more active than the parent compounds. © 2010 Wiley Periodicals, Inc. Heteroatom Chem 21:84–88, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20582


Food insecurity combined with chronic disease conditions is a risk factor for Emergency Department (ED) utilization, an indicator of poor quality of care. However, such an association is not certain among school‐age children with chronic conditions. Therefore, we aim to determine the association of food insecurity, chronic conditions, and ED utilization among school‐age children in the United States.


Previous research has demonstrated that musicians show superior neural sound discrimination when compared to non‐musicians, and that these changes emerge with accumulation of training. Our aim was to investigate whether individual differences in executive functions predict training‐related changes in neural sound discrimination. We measured event‐related potentials induced by sound changes coupled with tests for executive functions in musically trained and non‐trained children aged 9–11 years and 13–15 years. High performance in a set‐shifting task, indexing cognitive flexibility, was linked to enhanced maturation of neural sound discrimination in both musically trained and non‐trained children. Specifically, well‐performing musically trained children already showed large mismatch negativity (MMN) responses at a young age as well as at an older age, indicating accurate sound discrimination. In contrast, the musically trained low‐performing children still showed an increase in MMN amplitude with age, suggesting that they were behind their high‐performing peers in the development of sound discrimination. In the non‐trained group, in turn, only the high‐performing children showed evidence of an age‐related increase in MMN amplitude, and the low‐performing children showed a small MMN with no age‐related change. These latter results suggest an advantage in MMN development also for high‐performing non‐trained individuals. For the P3a amplitude, there was an age‐related increase only in the children who performed well in the set‐shifting task, irrespective of music training, indicating enhanced attention‐related processes in these children. Thus, the current study provides the first evidence that, in children, cognitive flexibility may influence age‐related and training‐related plasticity of neural sound discrimination.


As the foods and household manufacturing technology is developed, the packaging method of products is being changed from single to multi materials and layers. This study were focused on EPR carton packaging, economic and environmental expected effects were predicted by the improvements of packaging materials and structures to reduce effective packaging waste. Especially expected effects were predicted when improving the structure and material of aluminum laminated material was difficult to recycle. Thus, it was assumed the aseptic carton packaging laminated aluminum were replaced with silica laminated films. In conclusion, analysis of economic expected effects were undervalued in this study because of the limitation of assumptions, though this study has significance about a new approach by calculating the data different from the past that the conventional methods like predictive value of government's guidelines or goals.


The invention relates to a method for manufacturing vacuum heat-insulating plates by the utilization of coal ash and rice hull ash, and belongs to the technical field of manufacturing of the vacuum heat-insulating plates. The method for manufacturing the vacuum heat-insulating plates by the utilization of the coal ash and the rice hull ash is simple in production technology and low in cost, and the produced vacuum heat-insulating plates are reliable in performance. According to the technical scheme, the method is performed according to the following steps that a, the rice hull ash and the coal ash are taken to be mixed and stirred to be even, b, the mixed powder is conveyed to a forming machine in a pneumatic mode and is dried in the conveying process, c, the dried powder is extruded in a rolling mode, and core material powder is obtained after compression; the compressed core material powder is filled in a high-resistance film bag and is extruded again in a vibrating mode to form products to be sealed; the products to be sealed are placed into a vacuum box to be vacuumized, meanwhile, the products to be sealed are extruded and sealed in a hot-melting mode, and the vacuum heat-insulating plates are obtained. The method is mainly used for manufacturing the vacuum heat-insulating plates.


1. Beka F. T. The distal offshore Niger Delta: frontier prospects of a mature petroleum province /
F. T. Beka and M. N. Oti, G. Postma eds. Geology of
Deltas: Rotterdam, A. A. Balkema, 1995. —
Р. 237–241.
2. Demaison G. and Huizinga B. Genetic classification of petroleum systems using three factors:
charge, migration, and entrapment, Magoon L. B. and
Dow W.G. eds. The Petroleum System–From Source
to Trap, AAPG Memoir 60: Tulsa, American Association of Petroleum Geologists, 1994. — P. 73–89.
3. Ekweozor C. M. and Daukoru E. Northern delta
depobelt portion of the Akata-Agbada petroleum system, Niger Delta, Nigeria, Magoon L. B. and
Dow W. G. eds. The Petroleum System–From Source
to Trap, AAPG Memoir 60: Tulsa, American Association of Petroleum Geologists, 1994. — P. 599–614.
4. Energy Information Administration, 1998a,

5. Energy Information Administration, 1998b,

6. Frost B. R. A Cretaceous Niger Delta Petroleum
System, Extended Abstracts, AAPG/ABGP Hedberg
Research Symposium, Petroleum Systems of the South
Atlantic Margin, November 16–19, 1997, Rio de Janeiro, Brazil.
7. GeoMark Research, Inc., 1998, OILS: Oil Information Library System, version 1.0: Houston, Texas /
GeoMark Research, Inc., [database available from
GeoMark Research, Inc., 9748 Whithorn Drive, Houston, TX 77095].


Three coaxial quantized vortex rings in a Bose-Einstein condensate exhibit aperiodic leapfrogging dynamics. It is found that such circular vortex rings are dynamically unstable against deformation breaking axial rotational symmetry. The dynamics of the system are analyzed using the Gross-Pitaevskii and vortex-filament models. The dependence of the instability on the initial arrangement of the vortex rings is investigated. The system is found to be significantly unstable for a specific configuration of the three vortex rings.


Figure 2: example of volume (left) and filling rate (right) during a cardiac cycle using from retrospective triggered data for various numbers of reconstructed cardiac frames: 20(■), 50(∗), 70(▲), 90 (●). Figure 3: diastolic function parameters over time for non-diabetic (open bars) and diabetic (filled bars) mice. # P = 0.091 vs. db/+. ## P = 0.06 vs. db/+. * P < 0.05 vs. db/+. High spatio-temporal resolution retrospectively triggered CINE imaging for measuring diastolic function in mice Bram F Coolen, Desiree Abdurrachim, Abdallah GA Motaal, Klaas Nicolay, Gustav J Strijkers, and Jeanine J Prompers Biomedical NMR, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands


The clone of legal user's IP and MAC address has threatened the authentication, accounting and security, so it is necessary to quickly discover this illegal behavior in campus network. This paper first,analyzes the basic principle and the feasibility of cloning the IP and Mac address based on TCP/IP protocol. Then it presents a quick method for detecting the clone of IP and MAC address by using the principle of Gratuitous ARP, and gives some key codes realized by WinPcap and VC++6.0. Finally, it puts forward an idea on how to forbid the clone user to access the Internet.


Urbanization is the inevitable course of modernization in China,and peasant laborers,a special group in the shift of the rural labor force into the city,are sure to appear in our society in which the political reform lags behind the economic restructuring.With the acceleration of urbanization,they will be caught in a dilemma,so the present policy and system to solve this problem.


Electrical conductivity experiments on NiS 2−x Se x (x = 0.45) subjected to moderate pressure in the 30 – 800 mK range permit the investigation of quantum critical phenomena in this system. Detailed data are presented in the context of standard theories of correlation effects in the vicinity of a critical point. The critical exponents pertaining to these effects have been evaluated; the significance of these findings require further study.


In order to market a new medicine in the EU, 'medicine developers' (mainly pharmaceutical companies) must first submit a 'marketing authorisation application' to the European Medicines Agency (EMA). EMA evaluates the medicine and adopts an opinion on whether it should be authorised. Prior to submitting an application, medicine developers may seek and receive scientific advice from EMA. These 'pre-submission activities' may have some positive consequences for public health. However, it is important to avoid even the perception that the eventual opinions of EMA on medicines were influenced by these earlier interactions.


FDI in agriculture in developing countries is very small. It is not among priorities of most developing countries as regards FDI promotion and attraction. It is also not facilitated by often unresolved regulatory issues concerning access of investors to arable land. In addition, there a fewer candidates for foreign investment than there were several decades ago, as TNCs ― food processing and retailing TNCs as well as trading intermediaries ― withdrew from agricultural production and focus instead on downstream activities, including processing, trading and marketing of food. To secure agricultural inputs, TNCs as well as domestic players, establish local and cross-border supply chains, which they control, using for this purpose contracts with local farmers or buy inputs through spot market transactions. Therefore TNCs affect agriculture of most developing countries indirectly, through contracts, rather than directly, as producers of agricultural products. The paper examines implications of TNC activities for developing countries in the area of financing, investment and exports. TNCs can be instrumental in providing financing and other forms of assistance to farmers as well as in stimulating exports. They can, however, crowd out farmers, unable to meet stringent requirements of TNCs concerning quality, product safety or logistics. In addition, excessive concentration of market power of international trading companies in some international markets reduces benefits of developing countries from exports of agricultural products. In an exception from an overall pattern of small FDI in agriculture, some countries such as China and Viet Nam attracted considerable FDI into their agriculture.


In the 2020s, the Korean Peninsula seems to have further alienated its desire for peaceful reunification due to the North Korean nuclear threat that has continued for the past 20 years.
However, clues can be found to solve this crisis in the history of the last democratization movements, which have always pursued a unification movement with the change of dictatorship. This paper examines the nationalist ideal that has always accompanied Korea's democratization efforts, identifies the connection between the democratization movement and the unification movement, and presents contemporarily significant points based on the results. For the purpose of this study, the researcher introduces the traditional security view that has relied on military power by considering the South Korean people's sense of unification in the midst of the North Korean nuclear crisis in the 2020s and the realist opinion that leads the cause and feasibility of unification on economical terms. In addition, this research examines the pattern of the post-Cold War nationalist integration spirit that appeared in the unification movement process after the democratization movement, and highlights the connection point of the two major movements and their value of the time. This study has found that students and citizens who participated in the pro-democracy movement argued for nationalistic ideals against foreign intervention while resisting the authoritarian government's suppression of the pro-democracy movement in the name of the US-backed anti-communist line. This research is significant in that it emphasizes that continuous democracy practice is a key element of security in addition to military power by linking the two major movements ideologically.


The pathogenesis of periodontal lesions in the Mongolian gerbil (meriones ungiculatus) was studied in sixty-one animals varying in age from two months to five years. Both gross morphologic and histological techniques were employed. The results of this investigation indicate a slowly progressing, insidious form of inflammatory periodontal breakdown in this animal apparently related to the accumulation of plaque and calculus-like accretions. Because of the many morphologic similarities of the periodontal lesion in the gerbil to those of the human periodontal problem, it is felt that this animal is ideally suited for periodontal research.


Abstract 1541

Understanding the nature of renal erythropoietin-producing cells (REPs) remains a central challenge for understanding the mechanisms involved in hypoxia/anemia-induced erythropoietin (Epo) production in adult mammals. Previous studies have shown that REPs are renal peritubular cells, but further details are lacking. Here, we describe our approach used to isolate and characterize REPs. We bred mice bearing Epo/GFP combined with Epo-3'-enhancer deletion. These mice exhibit perinatal anemia (average Hct = 18% at P4–6). This enabled identification and purification of REPs based on GFP expression in the kidney. Light and confocal microscopy revealed that GFP immunostaining was confined to fibroblasts residing in the peritubular interstitium, which is consistent with our previous observation from the 180-Kb Epo/GFP reporter assay. Flow cytometry revealed that the GFP fraction constituted approximately 0.2% of the whole kidney cells; with most (63%) cells co-expressing CD73, a well-known marker for Epo-expressing cells. qRT-PCR confirmed that Epo expression was increased by approximately 100-fold in the purified REP population compared with that of the unsorted cells or CD73 fraction. Gene expression profiling showed Hif2α and Hif3α enrichment in the purified GFP/REP population. Moreover, in mouse hypoxia experiments, Epo expression was approximately 2.5-fold higher in Hif3α–/– kidney cells than in wild-type cells. The molecular strategy described here provides a means to isolate a pure population of REPs, allowing the analysis of gene expression profile of a defined population of cells essential for Epo production in the kidney. Our findings have led to a novel hypothesis that positive regulation by HIF2α and negative regulation by HIF3α might be necessary for correct renal Epo induction.

Disclosures: Yamamoto: Chugai Pharmaceutical, Co., Ltd.: Research Funding.


A Type Ia supernova explosion likely begins as a nuclear runaway near the center of a carbon-oxygen white dwarf. The outward-propagating flame is unstable to the Landau-Darrieus, Rayleigh-Taylor, and Kelvin-Helmholtz instabilities, which serve to accelerate it to a large fraction of the speed of sound. We investigate the Rayleigh-Taylor unstable flame at the transition from the flamelet regime to the distributed burning regime, around densities of 107 g cm-3, through detailed, fully resolved simulations. A low Mach number, adaptive mesh hydrodynamics code is used to achieve the necessary resolution and long timescales. As the density is varied, we see a fundamental change in the character of the burning: at the low end of the density range, the Rayleigh-Taylor instability dominates the burning, whereas at the high end, the burning suppresses the instability. In all cases, significant acceleration of the flame is observed, limited only by the size of the domain we are able to study. We discuss the implications of these results on the potential for a deflagration to detonation transition.


This article describes the research and development with the international advanced level of the screw separator, mainly used for the cleaner tailings fiber and the wastewater recycling and the use of stand-alone concentrated effect, into the plasma concentration of more than 0.5%, themaximum slurry concentration up to 60%, the device uses a unique control mechanism, without the power consumption will be able to achieve the automatic control of the plasma concentration, can efficiently remove moisture, recycled fiber, conservation of resources. 1Overview In pulping process,it will produce a certain amount of waste residue, also known as tailings. The tailings contain a large number of moisture content and fiber. Now, stacked tailings of many enterprises are in the outdoor. Severe pollution caused by a lot of stacked tailings, which don't do process.Loss of water and fiber caused great waste to the enterprise. To draw lessons from foreign advanced technology, it will design and develop the screw separator with advanced level at home and abroad, mainly used for the cleaner tailings fiber and the wastewater recycling. The current domestic pulp manufacturers don't do process tailings, direct discharge away, which is no processing equipment. So the development of the screw separator will fill the domestic blank.


With the development of Internet, more and more importance is being laid to the threats in cyberspace, which may have a profound effect on sustainable development of cyberspace. This paper aims at establishing a new concept of sustainability in cyberspace. Firstly, traditional sustainability was reviewed. And in the case of cyberspace, a general analysis was given to its status quo as well as the threats in a worldwide perspective. Then the sustainability in cyberspace was defined on the basis of traditional sustainability and above-mentioned analysis. In particular, the conception of sustainability in cyberspace was systematically programmed.


Based on the strategic issues of the development of rock and hill districts Siak Kecil as Industrial Zone, Port and Agribusiness demand developments, improvements and fixtures public roads. Road equipment that is needed is a street lighting (PJU). PJU condition mounted in the district of Bukit Batu and Siak Kecil using AC lamps with high wattage power thus increasing the burden of payment of electricity accounts PJU. This study makes setting brightness lamp LED 60 watts using Programble Logic Control (PLC). Adjust the brightness level control (Illumenation) based on time. Hours 1830WIB - 2200 WIB illumenasi used 100% and hours 2200 WIB - 0600 WIB illumenation only 70%., Then to electrical energy efficiency but does not reduce the comfort of road users, forming an industrial area that is energy efficient. Keywords: illumination, LED, PLC


Despite
its unpopularity, the rectal route of paediatric drug administration remains of
interest especially in pre-school children as it can overcome some drug
delivery challenges with oral and parenteral routes. Few studies have been conducted on the use and acceptability of
traditional rectal dosage forms (i.e., suppositories, enemas and gels) in
different parts of the world. It showed that barrier to adoption could be
linked with poor knowledge, little information and understanding of this
administration modality. Reformulation for the rectal delivery of drugs
intended for oral and/or parenteral administration that do not reach their full
potential, was explored by a study at University College London. The top 3
candidates were Azithromycin, Amodiaquine and Raltegravir. Little rectal delivery innovation has occurred but topics such as
acceptability and use of rectal drug delivery; types of rectal dosage forms and
reformulation considerations are discussed presently in order to raise
awareness around the need to modernise rectal dosage forms this to achieve the full potential for
successful reformulation.


A numerical and experimental study of a nearly-confocal resonator with two spherical mirrors is presented in this paper. The geometry was chosen in order to have a large quality factor for the diffraction losses at 12 GHz, and thereby a weak coupling to parasitic external TE and TM modes, that can propagate in a beam pipe on which the resonator may be installed. Simulations were performed with the time domain solver of the CST Microwave Studio simulation package and the frequency domain solver of Ansoft HFSS respectively. A large number of propagating modes in the beam pipe were numerically analyzed. In order to verify the theoretical studies, a prototype consisting of a nearly-confocal resonator installed onto a 30 cm long beam pipe, with a 20 cm long standard M-band waveguide connected to the upper spherical mirror, was fabricated and measured. Experimental results show a very good agreement with the simulations.


This paper describes the construction of a system that recognizes handprinted digits, using a combination of classical techniques and neural-net methods. The system has been trained and tested on real-world data, derived from zip codes seen on actual U.S. Mail. The system rejects a small percentage of the examples as unclassifiable, and achieves a very low error rate on the remaining examples. The system compares favorably with other state-of-the art recognizers. While some of the methods are specific to this task, it is hoped that many of the techniques will be applicable to a wide range of recognition tasks.


This study surveyed 185 parents to determine whether their perceived risk of their child developing obesity and their implicit theories about the malleability of weight independently and/or interactively predict their child-feeding and pursuit of child-related obesity risk information. Higher risk perceptions were associated with healthier feeding intentions and more information seeking. More incremental (malleable) beliefs predicted healthier feeding intentions and greater pursuit of environmental, but not genetic, information. Contrary to hypotheses, the influence of implicit theories and risk perceptions were primarily independent; however, more incremental beliefs predicted less "junk food" feeding among only parents with lower perceived risk.


The following interview with Dr. Les Roberts, Director of Health Policy at The International Rescue Committee (IRC), was conducted in May 2002. Previously, Dr. Roberts worked for WHO during the Rwandan Civil War of 1994 and at the US Centers for Disease Control and Prevention in Atlanta, both in the Refugee Health Unit and at the National Center for Environmental Health.


Thank you for reading progress in chaotic dynamics essays in honor of joseph fords 60th birthday. As you may know, people have look hundreds times for their favorite books like this progress in chaotic dynamics essays in honor of joseph fords 60th birthday, but end up in harmful downloads. Rather than reading a good book with a cup of tea in the afternoon, instead they juggled with some infectious virus inside their laptop.


The creation and development of the circular economy have its profound background.It is the outcome of the social particular history stage of mankind.The mankind society is the subsystem of the ecosystem.Its development has to be built up the foundation of the sustainable resources supply,and coexists with the natural environment.Being the mankind's activity centers of social economic system needs to follow the material metabolism modeof"the resources-product-reborn resources",not the one-way metabolism mode of"the resources-product-waste".This is the core thought that the cir- culation economy intends to express.


Cangrelor (Figure 1) is a parenteral drug that reversibly inhibits the P2Y12 receptor; like ticagrelor, it does not require metabolic activation. It has a rather short half-life of 3 to 4minutes; and, with an infusion of 4mg/kg per minute, peak inhibition occurs after 15minutes. Cangrelor also has a rapid offset, with normal levels of platelet aggregation returning after 60minutes. Inhibitors of platelet activation and aggregation are substances that are useful during percutaneous coronary intervention and other catheterization techniques in order to reduce bleeding complications and in the treatment of acute coronary syndromes and clotting disorders in general. One class of antiplatelet agents includes the inhibitors of the P2Y12 receptor, a G-protein coupled purinergic receptor which is an important component of platelet activation. Cangrelor (trade name kengreal in the US and kengrexal in Europe) was approved by the United States Food and Drug Administration in 2015. In continuation of our ongoing research to improve the process and identify impurities we now report a novel, convenient, and readily scalable approach for the synthesis of the key intermediate of cangrelor. A detailed study has been undertaken to identify, synthesize and characterize the cangrelor intermediates using up-to-date spectral techniques (IR, NMR, and HRMS). The synthesis of cangrelor has been reported in the literature starting from 2mercaptoadenosine (Scheme 1). The synthesis involves seven stages and additional purifications to get cangrelor. During the synthesis, compound 5 serves as a key precursor. This material is highly expensive. The reported preparation of this compound involves four steps. However, the preparation suffers from certain drawbacks, most importantly the availability of the starting material as being difficult to access. A lot of purification procedures were involved in each stage, and these present difficulties in scale-up. Therefore, a synthetic route starting from more readily available and cheaper substrates was sought. The synthetic process reported in the literature shows that the


Let $E/\mathbb{Q}$ be an elliptic curve, and let $L(E/\mathbb{Q}, s)$ be its Hasse-Weil $L$-series. In this paper, working under certain simplifying assumptions, we sketch a proof of the following result: $L(E/\mathbb{Q}, 1)\not= 0 \Longrightarrow E(\mathbb{Q})$ finite.


To study the suitability and applicability of standpipe piezometer, the issue of selection between embedded consolidation apparatus and standpipe piezometer in the paper Opinions of two issues in seepage pressure monitoring was discussed here. The conclusion was gotten that the standpipe piezometer was suitable in the area of gradually varied seepage flow instead of rapidly var-ied seepage flow area. As well, it clearly defined the integrated time lag. It was suggested that embedded consolidation apparatus should be selected for seepage pressure monitoring in the soils with low permeability and area of rapidly varied seepage flow.


Five skill and practice development modules:

(1) High-Performance Strategic Account Teams
(2) Senior Management Engagement
(3) From Strategy to Practice - Building Customer Action Plans
(4) Leading Without Authority
(5) Strategic Account Management in Your Own Practice


The paper presents a new Cyber Physical Stream algorithm for selecting a predominant item from very large collections of data. The algorithm effectively works for frequencies of the predominant items starting from about 2%. The algorithm is focused on querying massive data in Software-Defined Storage combined with Fuzzy indexing method. Experiment results show that Cyber Physical Stream algorithm improves the accuracy and efficiency over previous efforts.


Since a majority of information in the real world is uncertain and vague which is difficult for UML,fuzzy UML has been presented.Similar to UML,fuzzy UML is semi-formed and lacks precise semantics.In order to solve this problem,an approach to formalize fuzzy UML class diagrams with fuzzy description logics was proposed.The fuzzy description logic f-SHOIN was extended with concrete fuzzy domain,and the formalization of elements in fuzzy UML class diagram was decribed.This approach was applied to a fuzzy UML data model to verify that it was available.


The minimum edge termination length for various trench structure is theoretically determined to obtain universal curve for efficient design under considering trade-off relation with trench fabrication difficulty, cost and limitation specially for thin wafer IGBTs and diodes. This study unveils for the first time clear relationship between trench depth and termination length. We present practical design for each trench depth based on design curve considering trench filler material.


One of the major aspects of postcolonial retrospection of the British Raj in India is the fictional representation of the Raj in novels written either during that period or later. The Raj appeals to the imagination of the writer partly because of its historical timing, beginning as it did subsequent to the decline of Muslim imperialism as well as the romance associated with the conquest of a vast, alien land by the British Empire. The contrasts of race and culture, never so pronounced during Muslim imperialism, became a glaring colonial dimension with the establishment of the East India Company. Within the larger colonial context of racial and cultural disparity between the English and the natives there arose the more sensitive disparities of gender in which the relations between Englishmen and Indian women gained considerable acceptability with Englishmen taking Indian women as mistresses or wives in the absence of their female compatriots. By the beginning of the nineteenth century "interracial marriage gradually came to an end, though the 'native' concubine or bibi continued to be kept and interracial sexual liaisons continued to be widely and openly practised" (Sen 43). The two other categories of women with whom Englishmen consorted were the courtesans and the prostitutes. 1 More and more Englishwomen coming to India added a new dimension to gender relations with the Englishwoman's position vis-a-vis the native male coming under sharp scrutiny. This dimension acquired a provocative focus that significantly defines the larger disparities of race and culture. According to Aruna Chakravarti, during the early days of the Raj, "the isolated condition of the Englishmen in India resulted in many of them taking to Indian ways and marrying Indian women" (8), but these interracial liaisons did not get much fictional representation. Chakravarti points out that "The attitude hardened ... with the arrival of Englishwomen in India


The article discusses the development and impact of the German Council of Economic Experts (GCEE). Firstly, the author studies the historical origins and the institutional setup of the GCEE. In the second step, an analyse of the impact of the annual reports of the German Council is given, along with the international comparison with other advisory boards. Finally, the paper discusses the current economic challenges and the need of modernization of the GCEE in special and political advisory boards in general.


The relation between personal and social identity is a central motif in much "resistance" literature, including that produced by writers of the Irish Renaissance, African-American writers, anti-colonial Indian writers, post-colonial African writers, feminist women writers, and so on. Writers from such disenfranchised groups often seek to root their work in the denigrated traditions--the collective identity--of their society or, conversely, to examine the rootlessness of individuals, their lack of identity, in a society ravaged by oppression. Some authors have further specified the latter theme, looking in particular at the ways in which the repression or destruction of social identity may lead individual men and women to madness, here understood as a virtually complete loss of personal identity. The most famous treatment of the relation between social repression and individual insanity is theoretical: Frantz Fanon's "The Negro and Psychopathology" (Chapter Six of Black Skin, White Masks). But the topic has been widely explored by novelists, poets and playwrights as well. For example, in Dream on Monkey Mountain, Derek Walcott sets out to illustrate Fanon's ideas through the madness of Makak, a black man who longs to return to an Africa about which he knows little and with which he has little genuine cultural connection. From a different perspective, V. S. Naipaul treats this theme in the nervous collapse of the homeless and cultureless Mr. Biswas in A House for Mr. Biswas. In Wide Sargasso Sea, Jean Rhys develops Antoinette's madness in relation to the English denial of her Creole culture and in relation to patriarchal suppression of women. In Surfacing, Margaret Atwood takes up these concerns in connection with patriarchy and modernism--or "America," as she puts it. Bessie Head's A Question of Power is one of the most intense examinations of this theme. Like the psyche of its main character, Elizabeth, the novel itself divides into two conflicting stories. One focuses on Elizabeth's dayworld: memories of her life in South Africa, her unhappy marriage, her passage to Botswana, and now the daily experience of mothering her young son and working in Motabeng village. The other story focuses on Elizabeth's nightworld: a place filled with terror and threat, haunted by chimeras, most importantly the ambivalent figures of Sello, Dan and Medusa. The two stories join when Elizabeth suffers mental collapse, then struggles to reconstruct her life and to resolve the traumas manifest in her nightly delusions. The political and social background of Elizabeth's madness is explicit in the novel. She is a woman without a country (she is a refugee in Botswana), a race (she is neither black nor white, but colored), a culture (she is neither African nor European). Her political situation has repeatedly denied her any social identity whatsoever. It is for this reason that her personal identity warps and cracks under the pressure. As one character explains, "A lot of refugees have nervous breakdowns" (52). The narrator observes shortly thereafter that "the evils overwhelming [Elizabeth] were beginning to sound like South Africa from which she had fled" (57). Unsurprisingly, the political and ethical aspects of the novel have been emphasized by critics. As Roger Berger notes, "The criticism of A Question of Power...suggests in main how the novel concerns, in the context of apartheid, the question of evil" (31). As Linda Beard has indicated, many critics who do not focus on racism and related national politics, focus on the "feminist ideology" of the novel (577; see, for example, Bazin). Paul Lorenz expresses a common, and no doubt correct view, when he writes that A Question of Power "is a novel that demonstrates and directly confronts on a personal level, the interrelationships which exist between racism, sexism, and economic and cultural colonization" (592). Yet, to discuss this novel purely in terms of political and ethical themes is to miss its psychological depth and to misunderstand the structure and meaning of the delusions which occupy much of the book. …


We suggest that a very significant reduction in the group velocity of light occurs in a laser induced barrier-hopping process, known as "Laser Catalysis." In this process a system is made to hop over a potential barrier via a virtual transition to an excited bound state. As in electromagnetically induced transparency (EIT), the light absorption is predicted to dip to zero at a certain frequency, thereby also changing the refractive index, inducing in turn the slowing down of the group velocity of the light. In contrast to EIT, a single pulse is predicted to induce its own transparency and in contrast to self-induced transparency the process is predicted to be insensitive to the pulse area (as long as the pulse is intense enough to meet the adiabaticity criterion). Thus, the medium becomes transparent to the light, as the laser induced barrier-hopping process brings about a fundamental change in the medium.


Collapse of concrete buildings has elicited various researches on the quality of construction materials. Fine aggregates such as sand used in concrete production may contain excessive silt and clayey contents as well as organic impurities that impact negatively on the quality of hardened concrete. The objective of this research was to establish level of silt and clay content and organic impurities in building sand and its effect on bond strength of concrete. This paper presents the findings on the quality of building sand as sourced from eight supply points in Nairobi City County and its environs and the effects of sand impurities on the bond strength of concrete through the pull out test method to assess contribution of these impurities to the frequent collapse of buildings occurring in Kenya. Sieve analysis, specific gravity test, testing for silt and clay content and organic impurities were carried out as detailed in BSS 882, IS and ASTM standards. In casting of concrete specimens, the quality of cement, course aggregates (crushed stones), water and reinforcement bar were held constant while sand with varying level impurities and varying sources. The results showed that 86.2% and 50% of tested samples exceeded the allowable limits for silt and clay content and organic content respectively. It was observed that bond strength between concrete and reinforcement bars decreased with increase in silt and clay content while it increased and then decreased with increase in organic impurities. Predictive regression equations and were generated showing development of bond strength with varying levels of silt and clay, and organic impurities of building sand respectively. It is concluded that presence of these impurities in sand decreases the bond strength between concrete and reinforcement bars hence play a role in lowering the structural integrity of buildings. The research established that particle sizes, shape, texture and workability play an important role in determination of compressive strength of concrete.


Field-scale trials conducted over a three-year period in the Coalinga area of Fresno County show geographic source of California grown barley planting seed of the same variety has no significant effect on yield, if the quality is otherwise equal. Certified planting stock grown each year at three different geographic locations-Davis, Coalinga, and El Centro-was obtained and planted annually in replicated trials and harvested during 1958, 1959 and 1960. Purpose of the trials was to determine whether planting seed grown at a more southern latitude held any yield advantage over seed of a more northern origin. Each year's trials were conducted on Panoche loam soils prepared by accepted tillage operations and pre-irrigated with an average of 15 acre-inches of water. Each planting followed at least two years of seed alfalfa. Each trial received a preplant injection of about 50 pounds of actual nitrogen per acre in the form of anhydrous ammonia, except in 1959 when the fertilizer was applied by means of basin irrigation. Spring irrigation was through sprinklers. All planting seed was graded to uniform size and fungicide treated. Seed used was of either the certified, registered, or foundation class of certified


A broadband methodology for measurement of uniaxial dielectric anisotropy is described. Previous work is improved with reduced measurement error, enhanced automation, and additional material testing. Additionally, permittivity variation with temperature is explored.


Nitrogen oxides are in the center of future EURO VI norm, the European anti-pollution norm namely for Diesel powered vehicles. NOx (NO, NO2,...) are very irritant pollutants for people and are considered as tropospherical ozone precursors. Their effect is observed when ozone peak pollution is noticed during rush hours. A promising post-treatment technology is to add a NOx trap in exhaust line to store NOx under nitrate form. An alternative to fuel-air ratio increase and catalytic tech-nologies purge is the use of non-thermal plasma. Plasma reforming of diesel fuel and exhaust gas mix-ture creates reducing chemical species like hydrogen and carbon monoxide, which are able to purge the NOx trap.


Learning Objectives: The methods for predicting extubation success in critically ill children vary among individuals and institutions. Extubation readiness is a subjective assessment based on clinical evaluation of vital signs, lab values, and perceived requirement of ventilatory support. This study defined extubation readiness based on the physiologic state associated with successful extubations and developed a Recurrent Neural Network (RNN) to predict these physiologic states in individual patients. Methods: A retrospective study was conducted using EMR from patients admitted to the PICU at Children's Hospital of Los Angeles (CHLA) from 2009-2017. 1985 episodes were selected where patients were intubated for at least 12 hours, extubated without reintubation within 24 hours, and survived their PICU episode. Each episode contained 365 charted vitals, labs, interventions, and drugs during their PICU episode. The physiologic state associated with successful extubation was defined as the mean heart rate, systolic blood pressure, diastolic blood pressure, respiratory rate, and serum bicarbonate in the 6 hour window prior to extubation. An RNN was trained on all available variables prior to extubation to predict this state up to 6 hours prior to extubation and compared to age-normal values. Results: The mean absolute error for RNN predictions were compared to age-normal values. Heart rate was 16.0 vs 20.0 bpm, systolic blood pressure was 9.3 vs 11.0 mmHg, diastolic blood pressure was 9.2 vs 10.6 mmHg, respiratory rate was 5.0 vs 7.1 bpm, serum bicarbonate was 3.2 vs 3.8 mg/dL. Conclusions: The RNN model better approximates patient-specific physiologic states for successful extubation. Such a model can improve current extubation practice by personalizing assessments for extubation readiness, reducing complications associated with unsuccessful extubations.


To investigate the predictive value of renal sonography for vesicoureteral reflux (VUR) and the efficacy of renal sonography, technetium Tc 99m–labeled dimercaptosuccinic acid (DMSA) scanning, and a combination of the two for VUR screening in children younger than 2 years with a first episode of febrile urinary tract infection.


Objectives The purpose of this study is to analyze the trends in foreign clinical trials for pediatric asthma in complementary and alternative medicine (CAM) Methods We reviewed 31 randomized controlled trials (RCT) for pediatric asthma treatment in CAM published from 2005 to 2015 in PubMed and analyzed their treatments, compounds of herbal medicines, acupoints, methods of assessment, and treatment results. The treatments used in the studies were herbal medicines, acupuncture, acupoint application, breathing training, supplement, normocaloric diet, yoga, massage therapy, and art therapy. The frequently used herbs were Asari Herba Cum Radix ( 細辛 ). Ephedrae Herba ( 麻黃 ), Astragali Radix ( 黃芪 ). The most common acupoints were Feishu ( 肺兪 , BL13). The methods of assessment in pediatric asthma were symptom scale, questionnaire of Quality of Life, lung function test, laboratory studies, and medication usage. In 28 out of 31 studies, treatment group gets better than non-treated group. This study shows that CAM is effective in treating pediatric asthma. More clinical studies using objective outcome measures are needed to prove its efficacy clearly.


Introduction: Sexual violence in Colombia has become a serious public health problem; this type of violence has been associated with multiple individual, familial and social risk factors and it has been related to physical and psychosocial sequelae in the short, medium and long term. Method: In this descriptive study, factors associated with mental disorders were evaluated in 55 sexual violence victims seen at the Institute of Health in Bucaramanga, Colombia. Results: 43.6% had been abused in several occasions and 66.7% of the victims knew the aggressor. As associated factors, 21.6% of the victims had a psychiatric history and in 41% some member of the family had a psychiatric history. 60% had a history of family abuse, 25% considered family relations to be conflictive and 60% stated that the neighborhood where they lived was violent. At the beginning of this study, 87% presented with some type of finding in the mental examination and it was possible to establish an Axis I diagnosis in 72.7% of the cases. Conclusions: A history of family violence and mental illness in the family's victim as well living in violent communities are risk factors associated with sexual violence in our population. Anxiety, depressive and behavior disorders are the most frequent mental sequelae in this population.


A growing number of astronomical resources and data or information services are made available through the Internet. However valuable information is frequently hidden in a deluge of non-pertinent or non up-to-date documents. At a rst level, compilations of astronomical resources provide help for selecting relevant sites. Combining yellow-page services and meta-databases of active pointers may be an ecient solution to the data retrieval problem. Responses generated by submission of queries to a set of heterogeneous resources are dicult to merge or cross-match, because dierent data providers generally use dierent data formats: new endeavors are under way to tackle this problem. We review the technical challenges involved in trying to provide general search and discovery tools, and to integrate them through upper level interfaces.


Background: Hypertension is a common health problem among the elderly. Approximately 50% have poor adherence to their prescribed medication, which leads to uncontrolled blood pressure. This study was aimed to understand causes of poor adherence and gain knowledge of patient's self-management in their home. Methods: In-depth interviews were conducted. Elderly hypertension patients with poor adherence to antihypertension medication and uncontrol blood pressure, between the ages of 60-79 were purposively selected to participate in this study. Home visits, including observation of patient's behavior in their home, were conducted. Content analysis was performed. Results: A total of thirty respondents were interviewed of which 17 were female and 13 were male. All understood that hypertension is a chronic health problem but most of them were unaware that nonadherence to their hypertension medication treatment would lead to negative consequence to their health. Most respondents had negative beliefs toward hypertension treatment. The reasons for poor adherence are: 1) personal beliefs or habits, which include forgetfulness and negative belief that the medication will not control blood pressure; 2) side effects of medication and 3) negative perceptions influenced by the community. Research results showed that most participants were not taking their prescribed dosage. Additionally, expired medication was commonly found in their medication inventory. High sodium diets and no regular exercise was commonly reported. Conclusion: Patients understood that hypertension is a lifelong condition but unaware of consequence of poor adherence. Personal reason and negative belief as well as wrong belief influenced by community. Forgetfulness and manage dosage of medication should be addressed when designing a strategy to improve medical adherence. Education on controlling hypertension and treatments should be addressed and incorporated into a holistic strategy to improve adherence to the patient's drug regimen.


We describe multi-dimensional imaging systems based on single-pixel photodetectors and compressive sensing techniques. The key element in all cases is a spatial light modulator which sequentially generates a set of intensity light patterns to sample the input object. The optical architectures use off-the-shelf detectors, such as beam polarimeters and fiber spectrometers, with no spatial structure. The developed optical systems are applied to polarimetric, multispectral, and spectropolarimetric imaging.


Amateur Content Creation as Compositional Practice: Viral Videos and Internet Memes in Online Participatory Culture. Barnaby Goodman , Goldsmiths, University of London


A speed estimation method is presented in this paper for a grid connected doubly-fed slip-ring induction motor drive. The proposed method is formulated with reactive power based model reference adaptive system (MRAS). The method does not require any estimation of flux and is also independent of stator and rotor resistance variation. Extensive simulation results are presented to validate the technique. The proposed method is also simulated for regenerative mode of operation and the results obtained are satisfactory.


This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. © 2022 The Authors. The Kaohsiung Journal of Medical Sciences published by John Wiley & Sons Australia on behalf of Kaohsiung Medical University.


In the past decades, different kinds of bio-inspired algorithms have been proposed to solve optimization problems. Although these algorithms have shown good optimization performance in solving lower dimensional problems (D<100), many of them could hardly achieve promising solutions with increasing of dimensions. In this paper, an improved differential evolution algorithm, namely IDE, is proposed to solve high dimensional continuous optimization problems. The proposed approach employs a new mutation operator, which makes a good balance between local and global search. Simulation studies on six benchmark problems provided by CEC 2008 Special Session on Large Scale Global Optimization with D=100, D=500 and D=1000 show that IDE obtains better performance when compared with other five algorithms.


The study aims to examine the mediating effect of third party assurance (TPA) and the moderating effect of financial leverage in corporate social responsibility (CSR) on the relationship between financial performance in the manufacturing industry in Indonesia. The research was conducted on manufacturing companies listed on the IDX in 2018-2020. The analytical method used is panel data regression analysis method and moderation regression model. The results of the study show that CSR has a positive effect on financial performance. TPA has a negative effect on financial performance and does not mediate the relationship between CSR and financial performance. Financial leverage is not significant with financial performance, but moderates the relationship between CSR and financial performance in pure moderation. Then, financial leverage is not significant with TPA, but it can moderate the relationship between CSR and TPA in pure moderation.


The electrochemical properties of La9.33Si6O26(LSO)–La0.8Sr0.2Ga0.8Mg0.2O2.55(LSGM) electrolyte composites have been evaluated over NiO and La0.1Ca0.9MnO3 (LCM) electrodes using symmetric and asymmetrical cells of NiO/LSO–LSGM/NiO and NiO/LSO–LSGM/LCM, respectively. The Nyquist plot obtained from this study suggested that the new electrolyte system exhibits excellent performance over the NiO and LCM electrodes and shows an ideal Randel cell electrical circuit characteristic in both NiO/LSO–LSGM/NiO and NiO/LSO–LSGM/LCM cells. The area-specific resistance (ASR) and, the activation energy (Ea) of NiO/LSO–LSGM/NiO from the Arrhenius plot are lower than the NiO/LSO–LSGM/LCM, which is 0.30 Ω cm−2 and of 0.74 eV vs 0.40 Ω cm−2 with Ea of 0.76 eV, respectively.