OBJECTIVE
To screen antitumor active compounds, drug-like or leading compounds from Chinese traditional and herbal drugs.

METHODS
Eleven coumarin compounds isolated from the Chinese traditional and herbal drugs were studied for their antitumor activities in vitro by determining the inhibition rates against growth of human bladder carcinoma cell line E-J.

RESULTS
It showed that umbelliferone, scoparone, demethylfuropinarine, isopimpinellin, forbesoside, columbianadin, decursin and glycycoumarin inhibited the growth of human bladder carcinoma cell line E-J in vitro and their activities showed a concentration-effect relationship. The inhibitory effects of forbesoside, columbianadin, decursin and umbelliferone, with IC50 values of 7.50x10(-7), 2.30x10(-6), 6.00x10(-6) and 1.30x10(-6) mol/L, respectively, were stronger than those of the other tested compounds. However, xanthotoxin, esculin and sphondin did not inhibit the growth of human bladder carcinoma cell line E-J in this assay condition.

CONCLUSION
These findings indicate that forbesoside, columbianadin, esculin, decursin and umbelliferone would be effective or regarded as potent drug-like or leading compounds against human bladder carcinoma.


iv CHAPTER 1. GENERAL INTRODUCTION 1 CHAPTER 2. A CONSERVED MOTIF IN THE INTEGRASE C-TERMINI OF 18 TY1/COPIA RETROTRANSPOSONS IS NECESSARY FOR STABILITY OF INTEGRASE AND REVERSE TRANSCRIPTASE Abstract 18 Introduction 19 Results 20 Discussion 28 Experimental Procedures 32 References 35 CHAPTER 3. PHOSPHORYLATION REGULATES INTEGRATION OF THE 40 YEAST TY5 RETROTRANSPOSON INTO HETEROCHROMATIN Abstract 40 Introduction 41 Results 42 Discussion 52 Experimental Procedures 56 References 59 CHAPTER 4. RETROTRANSPOSON TARGET SITE SELECTION BY 63 IMITATION OF A CELLULAR PROTEIN Abstract 63 Introduction 64 Results 66


The purpose of the study was to identify the relationship between learning styles and entrepreneurial competencies among students in a Malaysian university. This is a descriptive study which used a self-administrated
questionnaire. The sample was 270 students who enrolled in
Entrepreneurship Course as a compulsory course in their respective programme of studies in Universiti Putra Malaysia (UPM). Overall, both Processing strategies (mean=3.16) and Regulation Strategies (mean=3.08)
indicated a moderate level. Concrete Processing strategies (mean=3.30;SD=0.68) was found to be the most preferred learning style. Lack of Regulation learning style (mean = 2.98; SD= 0.64) was the least preferred. Literature Programme, Technical programme and Science programme
students rated Concrete Processing as their most preferred learning style. The overall students obtained a high level of mean score for management competencies (mean=3.73; standard deviation=.0.58). Marketing competencies (mean=3.67; standard deviation=0.62) and financial competencies (mean=3.46; standard deviation=0.64) are at a moderate level. Overall, the students rated themselves as having a moderate level of entrepreneurial competencies (mean=3.62; standard deviation=0.61).
All the subscale of cognitive processing domain: deep processing, stepwise processing and concrete processing were significantly related to management, marketing and financial competencies at a moderate level. The
findings showed significant relationships between the different components of learning style and entrepreneurial competencies. The only component of learning styles that had insignificantly negative and negligible relationships
with management (r=-.036; p=.372), financial (r= -.110; p=.345), and marketing competencies (r= -.126; p=.606) was Lack of Regulation. It can be concluded that the relationship between learning styles and entrepreneurial
competencies among university students are significant. Findings had contributed to improve teaching and learning entrepreneurial competencies at university level.


The Contemporary Music Project and the MENC National Commission on Instruction endorse the Advanced Placement program in music as a significant means of improving the quality of music teaching and learning. By encouraging the development of advanced courses and more comprehensive experiences in music for high school students, this program seeks to meet the needs of a segment of the student population that can benefit from a special challenge. The objectives of AP music are consistent with those of both the CMP and the NCI.


107 Yunus Kaya, Adolescents' self-perception, parental attitudes and attachment / dx.doi.org/10.14744/phd.2020.74429 important to them and lay significant foundations for their adult personalities within their families.[11–13] Several factors play significant roles in the development of children and adolescents within families. The most important of them is parental attitudes. The changes that occur in adolescence are challenging and stressful, which is why parental attitudes are so important. However, dysfunctional families, incorrect parenting techniques and poor parental attitudes cause the difficulties and stress of adolescence to turn into problematic behaviors, which make it a difficult period for some adolescents.[13–16] Sometimes, parents can be over-monitoring, permissive or negligent in their support of the development of adolescents. Dysfunctional parental attitudes can increase the challenges of adolescence.[12,13,16] Baumrind studying on parental attitudes defined four types of parental attitudes: democratic, authoritarian, permissive and neglectful.[17–19] Democratic parents fulfill their children's basic needs for love, closeness, belonging, support and care, and they act responsibly. Authoritarian parents always monitor, control and manage their children's behaviors, but they are not responsive to their children's needs for love, care and closeness. Authoritarian parents create environments with rules they want their children to obey, and carefully monitor their children's obedience. Permissive parents fulfill and are responsive to their children's needs for attention, love, care and closeness, but they do not control, monitor and guide their children's behavior. Neglectful parents do not fulfill their children's emotional and psychological needs, nor do they control or monitor their children's behavior. Neglectful parents do not support or guide their children. Neglectful parents constantly criticize their children and neglect their needs.[17–19] Baumrind's ideal parental attitude involves supporting adolescents' autonomy and positive self-development, fulfilling their basic emotional and psychological needs and guiding them without making too many rules.[11,20] If adolescents are not given adequate love and support, are constantly criticized or punished for their behaviors, significant problems in their self-development can occur. Adolescents who grow up with democratic parental attitudes and strong attachments to their parents are more individualistic, healthier psychologically and assertive. They are also independent individuals who have better social competence and are able to manage their thoughts.[14,15,21] Attachment is the tendency for establishing strong bonds with others who are important to a person. Bowlby[22,23] suggests that the relationship babies establish with their primary caregivers form the basis for their attachment behavior with others in subsequent periods. Attachment patterns are shaped by mothers' reactions and greeting sensitivity to the physiological, emotional, psychological and security needs of newborns. Caregivers' fulfilling babies' basic emotional, psychological and security needs is the foundation of secure attachment.[22–25] Infants' secure attachments with caregivers are the basis for their subsequent relationships with others in adolescence and adulthood. Secure attachments are important for adolescents' development, socialization, individualization and autonomy.[23,24] Adolescents who have secure bonds with their parents are more trusting and satisfied and have better social skills and communication skills in their relationships with their peers than those who do not.[5,9,26,27] Adolescents who do not have secure bonds may completely drift apart from their parents and become depressed, anxious and lonely people who cannot establish close relationships or trust other people. They also try to cope with their problems on their own. This causes them to feel helpless and to have emotional difficulties, problems and dissatisfaction in their close relationships.[8,27–30] Adolescents who have secure attachments with their parents have higher social and emotional efficacy, and can ask for help and support, which supports their self-development in a positive way by affecting their physiological, emotional and physical health.[26,31–33] Adolescents try to adapt to the physical, psychological, social and cognitive changes that occur during adolescence and to be autonomous, to establish strong attachments, to discover themselves and to form healthy identities. Caregivers' fulfilling basic emotional and psychological needs, relationships based on trust and parental attitudes during early childhood are important factors in healthy adolescent development. Adolescence is difficult both for adolescents and their parents. Previous studies suggest that both adolescents and parents need guidance during adolescence.[34,35] Preventive mental health counseling for adolescents in developmental crisis and their parents will help them get through adolescence.[36,37] Parental support programs should be developed and implemented to help parents develop effective parental attitudes and reduce dysfunctional attitudes. Preventive mental health practices that improve adolescents' adaptation to development, strengthen their self-perception should also be planned for at-risk groups.[38–40] Psychiatric nurses should improve adolescents' adaptation to development by making therapeutic interventions to help them with issues What is known on this subject? • Relationships with parents and peers during adolescence lead to the establishment of secure attachments and the fulfillment of basic emotional and mental needs. They also contribute positively to self-development. What is the contribution of this paper? • Parental attitudes and secure attachment have a significant effect on the self-development of adolescents. This study's structural equation model found that secure attachment directly predicts self-perception, and that parental attitudes indirectly predict self-perception through attachment. What is its contribution to the practice? • Effective parenting skills help adolescents to fulfill the basic emotional and mental needs of their development, to have secure attachments in adolescence and adult life and to develop positive personalities. They also reduce psychological problems. 108 Psikiyatri Hemşireliği Dergisi Journal of Psychiatric Nursing such as knowing oneself, knowing and managing emotions, problem-solving and being assertive.[34,35] This study evaluates the roles of perceived parental attitudes and attachment styles in the self-perception of adolescents. Here are its research questions: 1) Is there a relationship between attachment styles (peer attachment or parent attachment) and the self-perception of adolescents? 2) Is there a relationship between the perceived parental attitudes and self-perception of adolescents? 3) Is there a relationship between the perceived parental attitudes and attachment styles of adolescents? 4) What are the roles of attachment styles and perceived parental attitudes in the self-perception of adolescents? Materials and Method


Oral squamous cell carcinoma (OSCC) is a very aggressive malignancy, and 50% of patients who receive curative treatment die from the disease or related complications within 5 years. Epigallocatechin‐3‐gallate (EGCG) is the most abundant bioactive ingredient of tea polyphenols in green tea and has anticancer properties. Here, we evaluated the preclinical efficacy of EGCG combined with vincristine sulfate (VCR) on the growth, angiogenic activity and vascular endothelial growth factor (VEGF) expression in xenograft nude mice inoculated with KBV200 cells. Compared with VCR alone, the combined use of EGCG and VCR strongly inhibited tumour growth and angiogenesis (P < 0.01). VEGF mRNA and protein levels were lower in the KBV200 xenograft group treated with the combined regime (P < 0.01) than those in the VCR alone group. EGCG sensitises multidrug‐resistant OSCC to VCR, and this may occur through the inhibition of angiogenesis via VEGF down‐regulation.


Nanotemplates with high-qualities play an important role in preparing well-aligned functional nanomaterials.However,it is difficult to evaluate the quality of nanotemplates quantitatively at present.In this paper,a computer program based on the general software MATLAB was proposed to extract quantitatively the geometric feature parameters from the morphology images of the nanotemplates.The proposed program can not only calculate the size parameters of the pores of the nanotemplates such as the porosity,the diameters and their variance by mathematical morphological operations,but also obtain the angle parameter of the pores arrangement by analyzing the morphology images with 2-dimensional fast Fourier transforms(FFT) and 1-dimensional FFT successively.After the accuracy and reliability of the proposed program was confirmed by processing a standard image,several scanning electron microscope(SEM) images of anodic aluminum oxide(AAO) templates,one of the most important nanotemplates,were analyzed.A reliable conclusion about the quality of the templates can be drawn based on both the size and angle parameters extracted with the proposed program.The application of the program will be helpful to optimize the templates preparation conditions and prepare functional nanomaterials in the future.


Objective To investigate the value of speed control midwifery fetal head protection for maternal perineal laceration. Methods From January 2012 to October 2014,one hundrad and twenty patients with vaginal delivery were selected as the research objects,and they were randomly divided into control group and study group with 60 cases in each group. The control group was given the midwifery of routine vaginal maternal protection,and the study group was given the midwifery of controlling the speed of fetal head. The incidence of perineal laceration,the degree of laceration,the second delivery process,the postpartum blood loss and the length of hospital stay were compared between the two groups. Results The incidence of perineal laceration and degree Ⅱ laceration rate of the observation group were 18. 33% and 3. 33% respectively,and 40. 00% and 24. 33% in the control group,the differences had statistically significant between the two groups( P 0. 05). In addition,the postpartum blood loss and the length of hospital stay of the observation group respectively were( 127. 60 ± 47. 28) ml and( 2. 40 ± 0. 33) d,the postpartum blood loss and the length of hospital stay of the control group respectively were( 179. 52 ± 89. 35) ml and( 3. 43 ±0. 62) d,and the differences had statistically significant between the two groups( P 0. 05). Conclusion The midwifery of controlling the speed of fetal head can reduce the incidence of maternal perineal laceration,and alleviate the degree of laceration and shorten the hospital stay,so it is worthy of clinical promoted application.


The Pseudo-Chrysostomian homily De compunctione et continentia (CPG 5062) is here edited for the first time, with a French translation, after a manuscript of the 14th century, the Oxoniensis Bodleianus Auctarium T. 3 12. The sermon, which is partly a patchwork quilt, would rather fit the corpus of the 'Greek Ephrem', as full of uncertainties as this ascription may be. Delivered in a monastic milieu, the preaching reflects a demanding ascetic spirituality, while exonerating the body of any responsibility for the passions of the soul.


16 children with various pulmonary symptoms were presented. Gastrooesophageal reflux was diagnosed as a cause of that. The causal correlation between gastrooesophageal reflux and respiratory symptoms was established on the ground of 24-hour monitoring of oesophageal pH, radioisotopic examination of the stomach and oesophagus, evaluation of the bronchial reactivity to the acidification of the oesophagus and of the allergic tests. Eventually surgical treatment was performed in all children which resulted in the complete remission of the symptoms or marked subjective improvement. It has been shown that gastrooesophageal reflux is an important cause of acute or chronic lung disease. The close collaboration should be established between pediatricians and pediatric surgeons in the treatment of gastrooesophageal reflux.


(57) Abstract: The present invention is a mammal (e.g., human) attached to a portion of the CC- chemokine receptor (2) (CCR2) or receptor, an antibody or functional blocks binding of a ligand to the receptor on the fragments. The present invention further relates to the use of antibodies and fragments in a method for inhibiting the interaction of cells producing mammalian CCR2 and its ligand, as well as prophylaxis and diagnosis methods.


This qualitative case study explores types of work-related information that novice teachers seek out and learn that is related to their daily work tasks. Eighteen experienced K-6 teachers offer their reflections about the dynamics of seeking and interpreting work-related information during their initial years of teaching. In-depth interviews were used to ask participants to reflect on their pathways of finding and using work-related information when they were novice teachers. The participants described nuances of their school settings that provided catalysts and barriers to gaining and using work-related information.


With self-designed equipment,the static relationship between the deformation of a NiMnGa alloy sample and the magnetic field is studied.The dynamic characteristics of this alloy sample under temperature,stress,magnetic field and strain are measured.As a result,a novel differential NiMnGa alloy actuator is proposed,which has fast response frequency and great output strain.The working principle of the designed actuator is explained.Experimental result shows the proposed system is feasible.


The power phenomenon has always called the attention of the human being, but with the same force with which power seduces, attracts and clouds the judgment those who come to hold it, it also generates in others eagerly the need to find the basis and the reason for that power and, especially, to put a limit on it, to control it, to justify its opposite: the right of resistance and civil disobedience. As we know, since ancient times, in Classical Greece with Sophocles and his work Antigone, or Aeschylus and his myth of Prometheus chained, the humankind has debated the limit of obedience to the law, to the ruler, to power, and when, under certain circumstances, disobedience or resistance is justified or "protected by the gods".


Disability discrimination also occurs when a covered employer or other entity treats an applicant or employee less favorably because she has a history of a disability (such as cancer that is controlled or in remission) or because she is believed to have a physical or mental impairment that is not transitory (lasting or expected to last six months or less) and minor (even if she does not have such an impairment).


In this paper, Particle Swarm Optimization (PSO) based technique for the optimal placement & setting of fuel cell in wind integrated power system is developed. By means of fuel cell optimal placement, it is intended to maximize the system loadability while observing the system stability margins viz., small signal stability, voltage stability, and line stability. The impact of optimal integration using PSO algorithm has been analyzed by studying different system parameters like voltage profile, line flows and real power generation. The objective function to maximize is the load power increase at various buses with respect to the base case load. The active power outputs from the distributed generators are adjusted from their base case power outputs in order to supply the additional load and to minimize the disturbance on the conventional generators due to the fluctuating outputs from wind turbine generators. The application of the scheme is illustrated on Central Travancore Practical Grid System. Newton Raphson power flow method and modal analysis are used to quantify the benefits of the proposed methodology. Results present the maximum system loadability in percentage, optimal location and setting of distributed energy resources, maximum safe bus loading beyond which system becomes unstable.


The parameters of legal visitation rights for grandparents in both biological and adoptive parenting situations are explored. Laws in each of the 50 states and the District of Columbia are summarized. Suggestions for improvement in the current system are included.


The continued exploration of a series of 3-(arylmethyl)-1H-indole-5-carboxamides by the introduction of fluorinated amide substituents has resulted in the discovery of 4-[[5-[((2R)-2-methyl-4,4,4-trifluorobutyl)carbamoyl]-1-methylindol-3-yl]methyl]-3-methoxy-N- [(2-methylphenyl)sulfonyl]benzamide (38p, ZENECA ZD 3523), which has been chosen for clinical evaluation. This compound exhibited a K i of 0.42 nM for displacement of [ 3 H]LTD 4 on guinea pig lung membranes, a pK B of 10.13±0.14 versus LTE 4 on guinea pig trachea, and an oral ED 50 of 1.14 μmol/kg opposite LTD 4 -induced bronchoconstriction in guinea pigs. The R enantiomer was found to be modestly more potent than the S enantiomer 38o. Modification of the amide substituent to afford achiral compounds was unsuccessful in achieving compoarable levels of activity. Profiling of 38p opposite a variety of functional assays has demonstrated the selectivity of this compound as a leulotriene receptor antagonist. The enantioselective synthesis of 38p, which employed a diastereoselective alkylation of (4R,5S)-3-oxo-4,4,4-trifluorobutyl)-4-methyl-5-phenyl-2-oxazolidinone (27) as the key step to establish the chirality of the amide substituent, provided an efficient route for generating 38p in >99% enantiomeric purity


The synthesis and characterization of substituted (trifluoromethoxy, thiomethyl, and methoxy) phenyl quinolines is described. Dichlorobis(triphenylphosphine)palladium(II)-catalyzed Suzuki–Miyaura cross-coupling of 6-bromo- and 6,8-dibromo-1,2,3,4-tetrahydroquinolines, 5-bromo-8-methoxyquinoline, and 5,7-dibromo-8-methoxyquinoline with substituted phenylboronic acids affords the corresponding 6-aryl- (13a–d), 6,8-diaryl- (14a–c), 5-aryl- (15), and 5,7-diaryl- (16b, c) tetrahydroquinolines and quinolines in high yields (68%–82%). The structures of all the products are characterized by 1H NMR, 13C NMR,19F NMR, and Fourier transform infrared spectroscopy and by elemental analysis.


PURPOSE: A process of preparing the titled sauce by passing through a series of processes to produce an aged product and then storing the aged product in a cold state is provided which can increase its taste while maintaining a flavor peculiar to a barbecued product and fried chicken. CONSTITUTION: A mixture of 15 to 30% by weight of high fructose corn syrup, 10 to 25% by weight of isomalto-oligosaccharide, 5 to 15% by weight of fermented soybean paste, 2 to 15% by weight of rice jelly(a kind of taffy), 2 to 15% by weight of soy sauce, 13 to 15% by weight of roasting sauce mix, 2 to 10% by weight of condensed milk, 1 to 8% by weight of acetyl adipate of starch, 1 to 8% by weight of purified sugar, 1 to 8% by weight of onion, 1 to 8% by weight of peanut butter, 0.5 to 3% by weight of garlic, 0.1 to 1% by weight of liquid caramel, and 5 to 20% by weight of purified water is heated at 80 to 100deg.C, added with 1 to 8% by weight of refined rice wine, and quickly cooled to -10 to -30deg.C after sterilizing. The cooled product is aged at 0 to 10deg.C for 12 to 36 hours and then stored at 0 to 10deg.C.


The present invention relates to a gas generator for converting a fuel into an oxygen-depleted gas and/or hydrogen-enriched gas. The gas generator, which may be used in any process requiring oxygen-depleted gas and/or hydrogen-enriched gas, is preferably used for generating protection gas or reducing gas for start up, shut down or emergency shut down of a SOFC or SOEC. The present invention further relates to processes for the conversion of fuels into an oxygen-depleted gas and/or a hydrogen-enriched gas.


The goal of toxicological risk assessment of human space flight is to identify and quantify significant risks to astronaut health from air pollution inside the vehicle or habitat, and to develop a strategy for control of those risks. The approach to completing a toxicological risk assessment involves data and experience on the frequency and severity of toxicological incidents that have occurred during space flight. Control of these incidents depends on being able to understand their cause from in-flight and ground-based analysis of air samples, crew reports of air quality, and known failures in containment of toxic chemicals. Toxicological risk assessment in exploration missions must be based on an evaluation of the unique toxic hazards presented by the habitat location. For example, lunar and Martian dust must be toxicologically evaluated to determine the appropriate control measures for exploration missions. Experience with near-earth flights has shown that the toxic products from fires present the highest risk to crew health from air pollution. Systems and payload leaks also present a significant hazard. The health risk from toxicity associated with materials offgassing or accumulation of human metabolites is generally well controlled. Early tests of lunar and Martian dust simulants have shown that each posses the potential to cause fibrosis in the lung in a murine model. Toxicological risks from air pollutants in space habitats originate from many sources. A number of risks have been identified through near-earth operations; however, the evaluation of additional new risks present during exploration missions will be a challenge.


Two full-scale test pavements (RTM1 and RTM2) and one rehabilitated, overlaid variant of the second test pavement (RTM3) have been tested in the Danish Road Testing Machine. These test pavements were instrumented to enable measurements of the strains and stresses in the pavement layers, and the resilient and permanent strains in the subgrade at specific loading repetitions. This report describes the RTM3 freeze-thaw study conducted during 1999. The temperatures and soil suctions in the pavement layers were measured during the freeze-thaw period. The development of pavement response and pavement performance under a constant 60 kN dual wheel load was very closely monitored during the early, critical stages of the thawing period. As a result of the RTM3 freeze-thaw study, a new subgrade permanent strain model has been developed from the research data from the RTM1, RTM2 and RTM3 test pavements, which were constructed, instrumented and load tested in the Danish Road Testing Machine between 1995 and 1999. The new model predicts the permanent strains in the subgrade. The coefficients and powers in the new stress-strain model were derived using measured data from the first two test pavement structures.


A retrospective survey was undertaken from three hospitals of 119 cases of breast carcinoma in women aged between 35 and 45 years, who presented to the hospitals over a 10–year period. It was found that the relative incidence of carcinoma of the breast in this age group does not differ greatly from that in other centres. The site, type and extent of carcinoma at presentation did not differ significantly from that in women or other age groups.


The BeiDou Navigation Satellite System (BDS) features a heterogeneous constellation so that it is difficult to mitigate the multipath in the coordinate-domain. Therefore, mitigating the multipath in the observation-domain becomes more important. Sidereal filtering is commonly used for multipath mitigation, which needs to calculate the orbit repeat time of each satellite. However, that poses a computational challenge and damages the integrity at the end of the multipath model. Therefore, this paper proposes a single-difference model based on the multipath hemispherical map (SD-MHM) to mitigate the BDS-2/BDS-3 multipath in a short baseline. The proposed method is converted from double-difference residuals to single-difference residuals, which is not restricted by the pivot satellite transformation. Moreover, it takes the elevation and the azimuth angles of the satellite as the independent variables of the multipath model. The SD-MHM overcomes the unequal observation time of some satellites and does not require specific hardware. The experimental results show that the SD-MHM reduces the root mean square of the positioning errors by 56.4%, 63.9%, and 67.4% in the east, north, and vertical directions; moreover, it contributes to an increase in the baseline accuracy from 1.97 to 0.84 mm. The proposed SD-MHM has significant advantages in multipath mitigation compared with the advanced sidereal filtering method. Besides, the SD-MHM also features an excellent multipath correction capability for observation data with a period of more than seven days. Therefore, the SD-MHM provides a universal strategy for BDS multipath mitigation.


Top Serviced Apartments in London for Construction workers. Discounted rates. Fully furnished flats. Free WiFi, kitchens and cleaning. Perfect for Short stays or Corporate accommodation.


From existing research evidence on the positive relationship between mindfulness and self-well-being, I predict that mindfulness has positive effects on interpersonal relationships. This research is focused on providing solid evidence of the positive relationships between mindful opinions and acceptance. The data is based on Bilibili (a website known as the Chinese version of Youtube), including 22,000 comments that are drawn from 11 types of videos, adding up to nearly 270,000 Chinese characters. All of those comments are analyzed one by one through a judging system created by myself. Using the judging system, the research first aims to verify the correction of the hypothesis and then demonstrate detailed connections between mindful opinions and acceptance. ("Main comments" in this paper refer to the comments directly below the video; "comments "in this paper refers to the comments of main comments).


The reactions of the Escherichia coli D-galactosebinding protein with the ligands D-galactose and Dglucose have been examined by stopped flow rapid mixing techniques. The change in tryptophan fluorescence that occurs with galactose binding is described by a rapid, second order process; no additional phases of fluorescence change were observed. The resultant time courses were fitted to a simple equilibrium model and the rate constants for galactose binding were calculated to be k,, = 3.3 x lo' M" s-l and koa = 4.6 s-l in 10 nm Tris-HC1, pH 7.4 at 20°C. In addition, the dissociation rate constants for glucose (1.4 s-') and galactose (4.5 s-') were determined directly from displacement reactions at high concentrations of the complimentary sugar. In both cases, the time courses were exponential in form and consistent with the first order release of sugar from a single binding site. We have also utilized a novel kinetic approach to determine the association rate constant for glucose binding (3 to 4 % lo7 M-' s-'). For all of these experiments, the data are consistent with a simple mechanism of sugar binding to a single site on the galactose-binding protein. We have also established that purified galactose-binding protein contains an approximately stoichiometric amount of bound glucose which can be readily removed by dialysis against 2 M guanidine HC1. The presence of bound glucose may account for the heterogeneous galactose equilibrium binding curves which have been reported in the past by other investigators.


Funk music, which emerged in the late 1960s and early 1970s as a distinct genre, sonically emphasizes rhythm and timbral heterogeneity. Politically and culturally, it addresses issues of equality and racial identity. However, because of the emphasis on rhythm and the kinetic movement of dancing bodies that funk inspires, it is frequently considered secular and sexualized, placing it in opposition to 'sacred' music. In this paper, I argue that funk offers an alternative framework that I call the spirituality of sensuality that bypasses the sacred/secular dichotomy. Funk does so by participating in the Afrodiasporic traditions where the concept of spirituality is embedded in and articulated through musical performance. Thus, rather than the either/or polarity that the sacred/secular divide creates, this paper demonstrates how funk expresses spirituality through the sensuousness of the sonic material.


This study aimed to investigate the appropriate carbon sources combined with molasses in a biofloc system for tilapia culture. Three carbon sources including rice bran, ground bread crumb and corn meal were selected to induce a biofloc system. This experiment was conducted in the concrete tank size 1 × 1 × 1 m3 with high aeration to achieve the dissolved oxygen at least 4 mg/L. The stocking density was 30 tilapia fingerlings/m3. Fish were fed with pellet feed followed tilapia feeding program and this experiment was run for six months. The water quality parameters were monitored twice a day. The results showed that there were no significant differences (P > 0.05) in weight gain, survival rate, average daily weight gain and specific growth rate among treatments while using molasses with ground bread crumb gave the highest feed conversion ratio and total suspended solid (P < 0.05). In summary, molasses combined with ground bread crumb was the best carbon source for biofloc production in tilapia culture.


The preparation and the structure of a copper(II) complex, [Cu(4ML)Cl] (1) (H4ML = 2-acetylpyridine-4-methylthiosemicarbazone), are described. Complex 1 crystallizes in a monoclinic P21/c space group with a = 7.977(2) Å, b = 15.824(5) Å, c = 9.126(2) Å, α = γ = 90°, β = 91.974(2)°, V = 1151.26(5) Å3, Z = 4, F(0 0 0) = 620. According to X-ray crystallographic studies, each Cu(II) ion lies in a square planar coordination geometry based on the 4ML− and Cl− ligands. The complex displayed excellent inhibitory activity against various tumor cells (HeLa, HepG-2 and SGC-7901), offering lower IC50 value of 3.2 ± 0.7 μM than cisplatin (10 ± 2 μM) on HeLa cells at 48 h. Complex 1 could significantly suppress HeLa cell viability in a dose-dependent manner. Flow cytometric analysis showed that 1 induced HeLa cell apoptosis, which might be associated with cell cycle arrests at S and G2 phases. Consistent with results of DNA cleavage experiments, comet assay indicated that 1 caused severe DNA fragmentation. The production of ROS was elevated with increasing concentration of 1, suggesting that 1 was capable of promoting HeLa cell apoptosis through an oxidative DNA damage pathway. Thiosemicarbazone Cu(II) complex exhibited great growth inhibition and induction of apoptosis in HeLa cells via oxidative DNA damage pathway which can act as a potential anticancer agent.


Background: bacterial vaginosis is universally the commonest vaginal infection in
reproductively active females. It causes major consequences as preterm labor,
predisposing to sexually-transmitted infections and HIV infections. Although it is a
public health concern, no one knows exactly its pathogenesis when some say that it is
just disturbance in vaginal floral balance predisposing to clinical symptoms and signs,
where the predominant Lactobacilli in vagina become replaced by other facultative and
anaerobic bacteria. Objective: To evaluate different diagnostic tests, Amsel's criteria
and PCR and their ability to diagnose bacterial vaginosis in comparison to the gold
standard test, Nugent score in terms of sensitivity, specificity, NPV and PPV. Also test
for prevalence of BV among included females. Methodology: screening was done for all
females in presence or absence of Amsel's criteria. Wet mount along with Gram stained
films were examined in Microbiology lab and Nugent score was calculated for every
patient. Cervico-vaginal aspirate samples were collected for detection of G. vaginalis,
Lactobacilli and Sialidase enzyme by multiplex PCR. Results: Using Nugent score
patients were categorized into bacterial vaginosis (BV) group (32%), non-BV group
(51%) and 17 % were in intermediate group. Sensitivity, specificity, PPV and NPV of
whole Amsel's criteria (100, 80.4, 76.2 and 100 % respectively) were better than using
any criterion alone. Using multiplex PCR, detection of G. vaginalis (100%) and sialidase
gene (93.7%) were higher in BV group and Lactobacilli gene (100%) higher in non-BV
group with statistically high significant difference. Multiplex PCR detection of G.
vaginalis has sensitivity (100%), specificity (92.2%), PPV (88.9%) and NPV (100%) for
diagnosis of BV in relation to the gold standard test, Nugent score. Conclusion: using
Amsel's criteria as a whole is better than using individual criteria for diagnosing BV
with highest sensitivity, specificity, NPV and PPV. Combined PCR detection of G.
vaginalis and sialidase gene can predict occurrence of virulent BV infection. BV is
associated with significant loss of protective Lactobacilli.


Coral collections and qualitative observations were made on the Bazaruto coral reefs in the Parque Nacional do Bazaruto. A checklist of species found on the reefs is presented with descriptions of their nature. Both the Alcyonacea and Scleractinia are well-represented on the reefs and their biodiversity is discussed in a regional context. The reefs constitute a valuable resource for ecotourism and recommendations are made for their sustainable use. Keywords : Coral reefs, Alcyonacea Scleractinia, Mozambique West Indian Ocean Journal of Marine Science Vol. 4 (2) 2005: pp. 227-236


PURPOSE
To conduct a pilot survey to assess acceptance of mobile teledermoscopy (MTD) by primary care nurse practitioners (NPs) working in Arizona.

DATA SOURCES
Sixty-two participants recruited from NP and academic listservs in Arizona completed an online survey prefaced by a MTD definition, device photographs, and a practice case, followed by 33 items measuring Teledermatology Technology Acceptance Model (TeleTAM) constructs.

CONCLUSIONS
Participants were highly interested in using MTD to assess skin lesions. They perceived MTD utility to greatly improve diagnosis and positively impact their practice. Most participants had never used MTD, but had high mean scores for MTD attitude and moderate scores for MTD perceived ease of use, perceived use, and facilitators of MTD. They had moderate scores for intention to use MTD. The construct facilitators (organizational infrastructure) were most strongly associated with intention to use MTD. Cronbach alphas were 0.70 or higher for all subscales except compatibility and habit.

IMPLICATIONS FOR PRACTICE
Moderate acceptance of MTD may reflect NPs' knowledge of the technology, self-confidence for using it, or MTD financial constraints. Future research will address these factors to foster use of MTD by NPs, thereby improving patients' access to early skin lesion assessment and diagnosis.


Motion of the vortex-current filaments is examined via cutoff Biot-Savart numerical MHD simulations of single and double filaments. We have introduced a vortex-current filament by analogy with the vortex filament. The vortex-current filament consists of electric current density and vorticity which are parallel to the axis of the filament. Attention is needed to demonstrate the difference between vortex and vortex-current filaments. In this paper we present two numerical results of vortex-current filament motion, using cutoff Biot-Savart method. In the limit of no electric current, the two results are in good agreement with vortex filament systems. The first result is obtained for two circular ring filaments. Here we find there are some cases where the qualitative characteristics of the motion are unchanged by introducing electric current along the vorticity. On the other hand, the period of the mutual slipping motion of the filaments is changed. The second result is related to oscillation of an elliptic r...


A rapid method was devised specifically for the cytological identification of translocations in the male mouse at late prophase to metaphase of meiotic division I, but the method should be useful for less specific objectives requiring examination of mammalian testicular material. For the adult mouse, masses of tubules from a single testis, freed of the testicular tunic, are placed in 3 ml of 0.7% sodium citrate for 15-20 min, and subsequently fixed in 50% acetic acid by the addition of 3 ml of glacial acetic acid to the hypotonic citrate. To facilitate handling of individual tubules by preserving their visible structure, the addition of fixative is at a rate which is grossly adjusted so that 2 ml will have been added at the end of 30 sec and the remaining 1 ml by the end of a minute. A single fixed tubule 1-2 cm long is placed lengthwise on a slide and covered with a drop of lactic-acetic orcein made as follows: Add 2 gm of synthetic orcein (G. T. Gurr) to a mixture of 50.0 ml of glacial acetic acid, 42.5...


The software-defined (SD) and edge computing (EC) are emerging technologies that have been used to improve the network operation efficiency of wireless sensor networks (WSNs). Due to the advantages of the SD and EC technologies, the area of WSNs has achieved a new dimension and breakthrough. However, the limited energy allocation mechanism in edge-SD wireless sensor networks (ESDWSNs) makes the energy consumption of different nodes unbalanced. In this paper, we propose an energy allocation optimization (EAO) algorithm that solves the energy averaging and minimization (ECAM) problem in ESDWSNs by selecting appropriate relay nodes and de-duplicated data flows. Specifically, we first establish a novel three-layer network architecture based on the edge computing and software-defined technologies. Then we proposed the ECAM problem, which minimizes the energy consumption in ESDWSNs. Furthermore, we propose an adaptive Levenberg-Marquardt algorithm and derive the optimization value of energy cost function. The extensive simulation results based on the NS-2 simulator demonstrate the energy balance efficiency of the EAO algorithm in ESDWSNs.


A previously healthy woman age 73 reported diplopia, fatigue and headache for the past two weeks, together with mild thirst and polyuria. On direct questioning, she gave a story of increased skin pallor, distal parasthesiae and longstanding cold intolerance. Blood pressure was 120/ 80mmHg with no postural fall. Visual acuities were 6/6 bilaterally and Goldmann visual fields were full. Hess testing revealed a right sixth cranial nerve palsy. Secondary sexual characteristics were preserved and there was no expressible galactorrhoea. Haemoglobin was 8.6 g/dL with a normochromic, normocytic film and erythrocyte sedimentation rate was 100mm in the first hour. Serum sodium concentration was raised at 152mmol/L. Serum contained an IgG kappa paraprotein (8 g/L) with associated immunoparesis and there was a Bence-Jones kappa fraction in the urine. Lateral skull X-ray showed erosion of the dorsum sellae. Chest X-ray and skeletal survey were unremarkable, as were computed tomographic scans of the chest and abdomen. Endocrine investigation disclosed secondary hypothyroidism (T4 54 nmol/L; TSH <0.1 mU/L) and inappropriately low gonadotropins for a postmenopausal woman (LH 1660nmol/L). Prolactin was greatly increased at 5020mU/L with an impaired (39%) increment following intravenous domperidone 10 mg. Formal water deprivation test revealed partial cranial diabetes insipidus (mean urine flow rate 36mL/h, peak serum osmolality 320mosmol/kg; peak urine osmolality 361 mosmol/kg rising to 734mosmol/kg after desmopressin). Pituitary magnetic resonance imaging (MRI) demonstrated a soft tissue mass filling the sphenoid sinus on the right and contiguous with the pituitary gland. There was thickening of the pituitary stalk and an enhancing mass in the floor of the third ventricle. Hydrocortisone replacement unmasked more florid diabetes insipidus requiring oral desmospressin. Thyroxine was started a few days later. Transsphenoidal exploration revealed an invasive tumour which proved to be a low-grade non-Hodgkin lymphoma. Most cells stained with B-cell markers but many T cells were also present. Prolactin immunostaining was negative. Cellular immunophenotyping ofbone marrow aspirate showed no evidence ofmyeloma. She was treated with radical radiotherapy (4000 cGy in 20 fractions) to sphenoid sinus and pituitary regions. On reassessment after radiotherapy, there had been resolution of the sixth nerve palsy, serum prolactin had fallen to 2360 mU/L and repeat MRI scan showed pronounced tumour regression. At latest follow-up, 21 months after radiotherapy, serum prolactin was 131OmU/L.


Gluons at small x in high-energy nuclei overlap in the longitudinal direction, so the nucleus acts as a single source of gluons, like higher Fock components in a single nucleon, which contribute to inelastic collisions with a high multiplicity of produced hadrons. This similarity helps to make a link between nuclear effects in pA and high-multiplicity pp collisions. Such a relation is well confirmed by data for the J/Psi production rate in high-multiplicity pp events measured recently in the ALICE experiment. Broadening of J/Psi transverse momentum is predicted for high-multiplicity pp collisions.


Since the tragic events of September 11th, the structural safety against terroristic attacks has become a relevant issue for strategic structures and the threat of malevolent attacks against a transportation infrastructure is very realistic. Bridges are strategic infrastructures with well-known importance for the community. A bridge failure is an event that compromises the socio economic stability of a country, and for this reason studying how to design and verify bridges under malevolent explosions followed by fire is a tactic for the defense of the community from terroristic attack. In this paper the structural response of a bridge engaged by fire of vehicles ignited after an explosion provoked by a track bomb is carried out. A set of structural nonlinear transient analyses is carried out by means of a finite element code, taking into account both thermoplastic properties of elements and geometrical nonlinearities. © 2012 Taylor & Francis Group.


In this paper, a novel global nonsingular fast terminal sliding mode control (GNFTSMC) method based on linear extended state observer (LESO) is proposed for Aerodynamic Heat Simulation Heating System (AHSHS). The global nonsingular fast terminal sliding mode surface (GNFTSMS), comprising constant reaching law and LESO, establishes a closed-loop control for the whole control process. Firstly, the designed GNFTSMS eliminates the reaching stage, so that the whole control process is confined on the sliding mode surface. The fast term and nonsingular term ensure convergence speed in the sliding phase, and eliminate the singularity and suppress the chattering phenomenon. Then, the constant reaching law can effectively solve the problem of convergence stagnation in the control process and further accelerate the convergence speed. Then, LESO can feed back the observation of input disturbances and external disturbances to the control system. Furthermore, Lyapunov stability theorem is utilized to prove the stability of the closed-loop system. Finally, the simulation results verify that the proposed GNFTSMC method based on LESO is superior.


We classify subsystem symmetry-protected topological (SSPT) phases in 3 + 1 dimensions (3 + 1D) protected by planar subsystem symmetries: short-range entangled phases which are dual to long-range entangled Abelian fracton topological orders via a generalized "gauging" duality. We distinguish between weak SSPTs, which can be constructed by stacking 2 + 1D SPTs, and strong SSPTs, which cannot. We identify signatures of strong phases, and show by explicit construction that such phases exist. A classification of strong phases is presented for an arbitrary finite Abelian group. Finally, we show that fracton orders realizable via p-string condensation are dual to weak SSPTs, while those dual to strong SSPTs exhibit statistical interactions prohibiting such a realization.


To achieve Anti-Jamming protection, DSSS Systems spread the baseband data signal over a broad bandwidth from the received signals with power below the noise floor. However, the existence of the near-far problem in multiple access DSSS Systems supports the notion that these signals can also be jammed though in normal case the detection of the DSSS Signals is difficult. The near-far problem is created by one signal (DSSS or otherwise) being significantly stronger than a DSSS signal within the same bandwidth so that the receiver is swamped by the first signal itself, which is similar to communication jamming phenomenon. In this paper performance of DSSS System are analyzed and the results are presented under different jamming conditions.


The concept of social and ethic aspects of marketing makes a strong case for introduction of social interests in making marketing decisions. As a major asset for engagement business structures into practices of sustainable behavior is their participation in socially significant marketing alliances with non-profit organizations for joint implementation of social projects. The authors of the article marked that within the alliances each of the partners achieves its own benefit within the framework of the win-win strategy. It is necessary to implement interdisciplinary approach to the study of socially significant marketing alliances. Authors propose to systemize the theory that form the theoretical and methodological basis of such alliances. It is underlined that at present it is possible to observe the wide spread of socially significant marketing alliances with the participation of the domestic banking sector. The practice of participation of Russian banks in socially significant marketing alliances is generalized and systematized. It is emphasized that it meets their economic interests, related to the diversification of business and the growth of customers' loyalty. In terms of practical implementation, calculations based on the author's methodology are presented, which allow assessing the economic effectiveness of the bank's participation in a socially significant marketing alliance on the example of a joint project of Sberbank of Russia and the charity fund "Gift of Life". In the conclusion, authors proved that the participation of banks in socially significant marketing alliances is an effective way of involving them in solving urgent social problems of society.


— Non-Destructive evaluation of in-service power transformer condition is necessary for avoiding catastrophic failures. Dissolved Gas Analysis (DGA) is one of the important methods. Traditional, statistical and intelligent DGA approaches have been adopted for accurate classification of incipient fault sources. Unfortunately, there are not often enough faulty patterns required for sufficient training of intelligent systems. By bootstrapping the shortcoming is expected to be alleviated and algorithms with better classification success rates to be obtained. In this paper the performance of an artificial neural network, K-Nearest Neighbour and support vector machine methods using bootstrapped data are detailed and shown that while the success rate of the ANN algorithms improves remarkably, the outcome of the others do not benefit so much from the provided enlarged data space. For assessment, two databases are employed: IEC TC10 and a dataset collected from reported data in papers. High average test success rate well exhibits the remarkable outcome.


This paper presents the largest In Situ Thermal Desorption (ISTD) project completed to date. The redevelopment of a former aerospace manufacturing facility adjacent to a commercial airport was the main driver, requiring relatively rapid reduction of several chlorinated volatile organic compounds (CVOC) in a 3.2‐acre source zone. The source zone was divided into four quadrants with differing treatment depths, heated simultaneously using a total of 907 thermal conduction heater wells. Five different depths were selected across the area, according to the depth of contaminant impact. Prior to implementation, a risk and optimization study led to placement of a vertical sheet‐pile wall around the treatment zone to minimize groundwater flow, and a pilot test of a novel direct‐drive method for installation of the heater casings. Because of a shallow water table, a layer of clean fill was placed over the treatment zone, and partial dewatering was necessary prior to heating. A network of vertical multiphase extraction wells and horizontal vapor extraction wells was used to establish hydraulic and pneumatic control and to capture the contaminants. The site was split into four decision units, each with a rigorous soil sampling program which included collecting a total of 270 confirmatory soil samples from locations with the highest pretreatment CVOC concentrations requiring reduction to below 1 mg/kg for each contaminant. Temperature monitoring and mass removal trends were used to trigger the sampling events. Eventually, a small area near the center of the site required the installation of four additional heaters before the soil goals were reached after 238 days of heating. The total energy usage for heating and treating the source area was 23 million kWh—slightly lower than the estimated 26.5 million kWh. Actual energy losses and the energy removal associated with the extracted steam were lower than anticipated. An estimated 13,400 kg (29,800 lbs) of CVOC mass was removed, and all soil goals were met. This paper presents the challenges associated with a project of this scale and describes the solutions to successfully complete the ISTD remedy.


The aim of this study is to analyse, by stadisctics and econometrics method, the existing relation between the gold and the gold bullion with more internacional prestige. In order to do a measure of relation and afterwards, we evaluate the influence level of the gold prices on the gold bullions prices analyzed.


Research into flow instability at both subcritical and supercritical pressures has attracted attention in recent years because of its potential of occurrence in industrial heat transfer systems. Flow instability has the potential to affect the safety of design and operation of heat transfer equipment. Flow instability is therefore undesirable and should be avoided in the design and operation of industrial equipment. Rahman et al. reviewed studies on supercritical water heat transfer with the aim of providing references for SCWR researchers. It was found out that most of the CFD studies and experimental studies were performed with single tube geometry due to the complexity of parallel channel geometry. Because studies performed with parallel channel geometry could provide detailed information to the design of the SCWR core, they called for more studies in parallel channel geometry at supercritical pressures in the future. In order to help understand how flow instability investigations are carried out and also highlight the need to understand flow instability phenomenon and equip the designers and operators of industrial heat transfer equipment with the needed knowledge on flow instability, this study carried out a review of flow instability in parallel channels with water at supercritical pressures.


For many years, the political and public discourse of developed countries has seen an increase in the focus on ethical and moral principles in operational and organizational activities. There are plenty of examples of public arguments concerning organizational undertakings that have bearings on unethical practices such as those of Arthur Anderson and Enron, Lincoln Savings and Loan Association, WorldCom, Ahold, Parmalat, and Bernard L. Madoff Securities LLC. Many believe the previous and other scandals provide evidence that shareholder theory has failed and that stakeholder theory has been victorious, alluding that it is the manager's role to create a balance between the financial interest of its shareholders and the interest of stakeholders even if it lessens shareholder returns (Smith, 2003a). However, in this context, current issues may have put additional pressures on organizations with added focus on matters such as the environment, taxation annulments, abuse of cheap labor in developing countries, the social role of organizations, integrity, and executive remunerations. On a global scale, many economic activities are under the control of large organizations, whereby, they call for a form of accountability in a democratic manner, but also in a manner that is in line with national governments (Mitchell & Sikka, 2005). Moreover, public opinion on policies plays an important part in democratic societies where the social role of organizations appears to directly affect how society is organized as well as the life prospects of individuals who largely depend on organizations for essential products and services.


Book Information Well-Being and Morality: Essays in Honour of James Griffin. Edited by Roger Crisp and Brad Hooker. Clarendon Press. Oxford. 2000. Pp. xii + 316. Hardback, £35.


By means of Monte Carlo computer simulations in the isothermal-isobaric ensemble, we investigated the interaction of a hydrophobic ligand with the hydrophobic surfaces of various curvatures (planar, convex and concave). A simple two-dimensional model of water, hydrophobic ligand and surface was used. Hydration/dehidration phenomena concerning water molecules confined close to the molecular surface were investigated. A notable dewetting of the hydrophobic surfaces was observed together with the reorientation of the water molecules close to the surface. The hydrogen bonding network was formed to accommodate cavities next to the surfaces as well as beyond the first hydration shell. The effects were most strongly pronounced in the case of concave surfaces having large curvature. This simplified model can be further used to evaluate the thermodynamic fingerprint of the docking of hydrophobic ligands.


Software product line (SPL) now faces major scalability problems because of technical advances of the past decades. However, using traditional approaches of software engineering to deal with this increasing scalability is not feasible. Therefore, new techniques must be provided in order to resolve scalability issues. For such a purpose, we propose through this paper a modularization approach according to two dimensions: In the first dimension we use Island algorithm in order to obtain structural modules. In the second dimension we decompose obtained modules according to features binding time so as to obtain dynamic sub-modules.


This paper presents an improved model of nonlinear actuator, as example of three-phase asynchronous motor, being an integral part of automatic mooring winch. For such technical objects, a mathematical model of auxiliary parametric sensitivity was developed, which becomes the real unifying factor that make it possible to analyze the nonlinear technical systems based on general theory of nonlinear differential equations combining into one algorithms all stages of analysis: calculation of transitive and steady-state processes, determination of static stability and parametric sensitivity.


The authors formulate the concept of constitutional law-making; generally the essence, the content and structure are revealed starting from the stage of needs in the legal settlement of underlying social relations up to the direct process of adoption of the Constitution and its amendments. In the course of research characteristics of the constitutional law-making of the Russian Federation are identified and analyzed at present stage. A number of disadvantages of the process, including some haste of the legislator in making legislative decisions and lack of awareness of the wider population about the grounds for adjustment of the Basic law of the country, is given.


The paper will review some of the latest developments in flash radiography. A series of multi anode tubes has been developed. These are tubes with several x-ray sources within the same vacuum enclosure. The x-ray sources are closely spaced, to come as close as possible to a single source. The x-ray sources are sequentially pulsed, at times that can be independently chosen. Tubes for voltages in the range 150 - 500 kV, with up to eight x-ray sources, will be described. Combining a multi anode tube with an intensified CCD camera, will make it possible to generate short "x-ray movies". A new flash x-ray control system has been developed. The system is operated from a PC or Laptop. All parameters of a multi channel flash x-ray system can be remotely set and monitored. The system will automatically store important operation parameters.


As part of the 1999 NC-140 Dwarf Apple Rootstock Trial, a planting of McIntosh on 11 rootstocks was established at the University of Massachusetts Cold Spring Orchard Research & Education Center in 1999. The planting included six replications in a randomized-complete-block design. This trial was planted in several locations throughout the United States and Canada, but only Massachusetts data are reported here. Means from 2005 (7th growing season) and cumulative means are included in Table 1 and Figure 1. Rootstocks in this trial include G.16N and G.16T. These are two forms (N liners were from normal stool beds and T liners were from tissue-culture-based stool beds) of G.16 from the Cornell-Geneva Apple Rootstock Breeding Program (a cooperative effort between Cornell University and the United States Department of Agriculture). The four CG rootstocks are as yet unnamed rootstocks from the same program. The Supporter rootstocks were released from the Institut fur Obstforschung Dresden-Pillnitz At the end of the 2005 season, largest trees were on CG.4013 and CG.5202, and the smallest were on M.9 NAKBT337, Supporter 1, and Supporter 2 (Table 1, Figure 1). Trees on G.16 and Supporter 3 were slightly, but not significantly smaller than those on M.26 EMLA, and trees on CG.3041 were similar in


Objectives: The social stigma associated with epilepsy can be a major cause of concealment of illness. This behavior is associated with many neuropsychiatric disorders. Sleep is an important factor affecting epilepsy and seizures. The aim of this study was to evaluate concealment of illness, sleep disorders, and related factors in epilepsy. Methods: A total of 95 primary epilepsy patients who were referred to the neurology outpatient clinic were included in the study. The demographic and clinical characteristics of the patients were recorded. Concealment of illness was measured using a scale consisting of 17 questions, and the Pittsburgh Sleep Quality Index (PSQI), consisting of 24 questions, was also administered to assess sleep disorders. Results: There were 44 (46.3%) female and 51 (53.7%) male epilepsy patients in the study. The mean concealment score was 57.09±8.96 and the mean PSQI score was 8.12±3.09. Sleep latency was significantly prolonged, and sleep efficiency and daytime functions were impaired. Indications of a sleep disorder were greater in young people (p<0.05; r=0.50). There was a negative correlation between age and concealment of illness (p<0.05; r=0.65) and a positive correlation between concealment of illness and a sleep disorder (p<0.05; r=0.54). Conclusion: The concealment of illness had a negative effects on sleep quality in patients with epilepsy. Concealment and sleep disorders increased as age decreased; therefore, it is especially important to evaluate young epilepsy patients carefully.


Buyer finance has been practiced by manufacturers/assemblers for years; however, few papers have investigated the efficacy of buyer finance in an assembly system with multiple suppliers. This paper fills the literature gap by comparing buyer finance with bank finance in a supply chain with one assembler and multiple heterogeneous capital-constrained component suppliers. We characterize the equilibrium solutions for different financing schemes (i.e., buyer finance, bank finance, and no finance). We show that in buyer finance the assembler should charge the suppliers the lowest possible interest rate, which may be even below its own unit capital opportunity cost, leading to losses in financing suppliers. However, the assembler can benefit more from enhanced inventory backup and lower component purchasing prices resulted from the low buyer finance interest rate. We further compare the different financing schemes from the perspectives of assembler, (borrowing and non-borrowing) suppliers, and the whole supply chain. Our analysis reveals that the assembler may offer buyer finance even if its own unit capital opportunity cost is higher than banks' risk-free interest rate. We also identify the conditions under which buyer finance is better than bank finance for each party as well as the whole supply chain, and demonstrate how the suppliers' initial capitals, production costs, and their heterogeneities affect the assembler's selection of the optimal financing scheme.


The invention discloses an information saving method and a terminal. The method comprises determining an operation system for processing information in a plurality of operation systems according to attributes of received information; determining whether the current operation system is the operation system; storing the information in a temporary storage region when the current operation system is not the operation system; selecting a storage position to save the information according to the information attributes when the current operation system is the operation system, wherein the storage position comprises the temporary storage region or a current operation system storage region. By means of the method and the terminal, the information can be saved in the temporary storage region out of the current operation system when users is inconvenient to process the received information or cannot process the received information timely, so that leakage of the information in the current operation system is prevented, the user privacy safety is improved greatly, and the user experience is improved.


Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal genetic disease that results in abnormal bone formation (heterotopic ossification) in areas of skeletal muscles and connective tissues. Genetic studies have identified the causative mutations in Activin-like kinase 2 (ALK2), a type I receptor of bone morphogenetic proteins (BMPs). Currently no effective treatments are available for FOP, and the disease is often misdiagnosed for less awareness. It is believed that China has the largest number of FOP patients in the world due to its population. However, most Chinese FOP studies were reported in mandarin, instead of English, the international language of science. In this article, I have identified 126 reported Chinese FOP cases by literature search and analyzed these cases from aspects of disease epidemiology, great toe clinical sign, causative mutations and onset ages. In addition, I summarize the most updated knowledge as well as current ongoing clinical trials in FOP field.


The abnormal results obtained as a result of prolonged dialysis of the amylase from Zea mais (Patwardhan, J. -Indian Inst. Sci., 1929, 12A, 185) interested the author to extend the investigation to similar enzymes from other seeds. The present investigation deals with the enzyme from ragi.


Nepali social work has Western liberal roots and traditions that impose cultural imperialism, professional sectarianism, and political colonization. There is a mismatch between what is taught in social work education programs in Nepal and Nepali culture. Further, this borrowed social work concept is out of step with the structural problems that Nepali people face on a daily basis, such as casteism, ethnocentrism, poverty, and exclusion. In this study, being inclined to critical pedagogy and decolonization discourse, I argue that Nepali social workers should emphasize and engage in decolonizing social work practice in Nepal. It must listen to the voice of the people at the grassroots and engage in 'people-centred development' to address structural problems perpetuating injustice and inequality in Nepal.


Abstract I have argued that careful thought needs to be given to the question of whether psychologists should try to monopolise psychological knowledge or participate actively in its dissemination (James, 1994). My purpose in putting this argument was to draw attention to changing conceptions of health and well-being, and the important implications that these changes have for the future role of professional and academic psychology.


Networks are a generic structure that allows representing a great diversity of systems. They are modeled by mathematical graphs, which have the capacity to contain a lot of information in their topology, but schematically they are only entities that somehow are connected to each other. This simplicity explains why there are many areas of application since connections are frequent in the real world. However, analyzing this architecture is not simple. Even if the presence of certain entities reveals information, it is very little related to what can be found if the relationships are considered. The presence of a subgraph in a network, and how often it appears, may be indicative of something extremely important. For this reason, the identification of patterns, and other characteristics, are relatively well explored areas in recent years and shows that it will be an area that will continue to grow. However, this problem of identification and counting of subgraphs, algorithmically speaking, is a hard obstacle without a known polynomial solution. This causes most of the works to fight the problem in its simplest form ignoring features that the networks present and that can and should start to be considered. Layers are a new aspect that is being added to the structure. Studying and gaining knowledge about networks with these special features is the main goal of this thesis, especially by detecting and counting of subgraphs. However, everything as we know it so far is different in this new context, even a simple subgraph that is the basis of this work. Therefore, the work done should be improved to follow this evolution of systems. After carefully studying the most diverse methods of network analysis this project defined its new approach by implementing some important mathematical concepts and adapting other methods. After going through and showing some techniques and ideas, which we consider necessary for this work, we describe in detail how we get our own results. First, we contribute to defining concepts in a novel area. An aggregation to identify subgraphs followed by a backtrack to make a reduction for identify isomorphic classes is the summary of our own approach. It allows us to obtain and discover patterns, which we show in our results section, created with a powerful visualization tool that we have developed. We also present our execution times and we evaluate our process in synthetic networks through classical models adapted to contain layers. Keywords— multiplex, networks, subgraphs, patterns, motifs


Marine transportation has an important role to support the national connectivity and economic growth, especially in Papua Province. Characteristics of geography on land and sea and an insufficiency of existing infrastructure in Papua encourage its development. An effort to improve Papua's connectivity and economic growth is believed to be able to overcome the complicated problems that exist today The aim of this study was to analyze the development of marine transportation in support of national connectivity and economic growth in Papua province. The contributions of marine transportation to the economy and the growth rate of marine transportation were analyzed using approaches of contribution sector and Typology Klassen, respectively. The problems and an overview of the steps in development of marine transportation in Papua and national were analyzed qualitatively using Miles and Huberman's method (1992). Efforts to increase the national transport connectivity were analyzed descriptively based on supporting documents. The results show thatthere has been an increase in the contribution of sub marine transport, transportation and communications in 2007-2013; The growth rate of marine transportation  increased in the period 2007-2012, then was corrected in 2013; the transport sector grows rapidly, however it is very difficult to optimalyzed related to several factors, both in the central and local government, infrastructure, local human resources, local community institutions, economic analysis up to external problems; the improvement of national transport connectivity can be realized by implementing strategies stipulated in national development planning documents concerning  Sislognas, Sistranas, RPJMN /RTRWN, ICT and Papua's planning documents.


Michael addition and UV-initiated radical polymerization of vinyl monomers were used for a one-pot synthesis of polyester-based double-network (DN) gels by chemoselective cross-linking at room temperature. Unsaturated copolyesters containing itaconate and maleate units were prepared via ternary polycondensation of maleic anhydride and itaconic anhydride with 3-methyl-1,5-pentanediol under mild conditions. The addition of a diamine to a mixture of unsaturated copolyester, methyl methacrylate (MMA), and UV-initiator in toluene at room temperature yielded the first network via chemoselective cross-linking of maleate double bonds. This network, containing MMA, was next irradiated under UV-light for 3 h to obtain a polyester/poly(MMA) DN gel with high mechanical strength and shape recovery properties. A poly(ester-co-ether)/poly(acryl amide) DN hydrogel, which swelled with 70 wt% of water after immersion in water, was also synthesized by a similar procedure.


We report on magnetron deposition and superconducting properties of a novel superconducting material: rhenium-lutetium films on sapphire substrates. Different compositions of Re$_{x}$Lu binary are explored from $x\approx 3.8$ to close to pure Re stoichiometry. The highest critical temperature, up to $T_{c}\approx $ 6.95 K, is obtained for $x\approx 10.5$. Depending on the deposition conditions, polycrystalline or amorphous films are obtainable, both of which are interesting for practice. Crystalline structure of polycrystalline phase is identified using grazing incidence X-ray diffractometry as a non-centrosymmetric superconductor. Superconducting properties were characterized both resistively and magnetically. Demonstration of superconductivity in this material justifies the point of view that Lu plays a role of group 3 transition metal in period 6 of the Periodic table of elements. In analogy with Re$_{0.82}$Nb$_{0.18}$, Re$_{6}$Ti, Re$_{6}$Hf and Re$_{6}$Zr, one can expect that crystalline Re--Lu is also breaking the time-reversal symmetry (this still waits confirmation). Magnetoresistivity and AC/DC susceptibility measurements allowed us to determine H$_{c1}$ and H$_{c2}$ of these films, as well as estimate coherence length $\xi (0)$ and magnetic penetration depth $\lambda _{L}(0)$. We also provide information on surface morphology of these films.


Background Previous studies have demonstrated that heatshock treatment results in the induction of 72-kD heat-shock protein (HSP72) and a reduction of infarct size after subsequent ischemia and reperfusion. Methods and Results To test the hypothesis that the degree of protection from ischemic injury in heat-shocked rats correlates with the degree of prior HSP72 induction, rats pretreated with 40°C, 41°C, or 42°C of whole-body hyperthermia followed by 24 hours of recovery and control rats (n=6 in each group) were quantitatively assessed for the presence of myocardial HSP72 by optical densitometry of Western blots and a primary antibody that is specific for HSP72 and a tertiary antibody labeled with `I. Although rats heat-shocked to 40°C had no significant induction of myocardial HSP72, rats heat-shocked to 41°C and 42°C demonstrated progressively increased


The aggregative adsorption of a nonionic surfactant (C12E5) in the cylindrical pores of SBA-15 ordered mesoporous silica (pore diameter 8 nm) was studied by small-angle neutron scattering (SANS). Scattering profiles obtained at contrast-matching conditions between the aqueous solvent and the silica matrix can be represented quantitatively by an analytical scattering function for the diffuse small-angle scattering superimposed with Bragg reflections from the pore lattice. These two contributions provide complementary information about the self-assembly of the surfactant in the pores: diffuse scattering indicates the formation of surfactant aggregates at preferred distances from each other, and analysis of the Bragg peaks shows that a layer of surfactant is formed at the pore walls. These findings suggest that adsorption of the surfactant starts by formation of discrete surface aggregates, which increase in number and later merge to interconnected patches as the plateau of the adsorption isotherm is approached.


Purpose The molecular mechanism underlying the carcinogenesis and development of lung squamous cell carcinoma (LUSC) has not been sufficiently elucidated. This analysis was performed to find pivotal genes and explore their prognostic roles in LUSC. Methods A microarray dataset from GEO (GSE19188) and a TCGA-LUSC dataset were used to identify differentially co-expressed genes through Weighted Gene Co-expression Network Analysis (WGCNA) and differential gene expression analysis. We conducted functional enrichment analyses of differentially co-expressed genes and established a protein-protein interaction (PPI) network. Then, we identified the top 10 hub genes using the Maximal Clique Centrality (MCC) algorithm. We performed overall survival (OS) analysis of these hub genes among LUSC cases. GSEA analyses of survival-related hub genes were conducted. Ultimately, the GEO and The Human Protein Atlas (THPA) databases and immunohistochemistry (IHC) results from the real world were used to verify our findings. Results A list of 576 differentially co-expressed genes were selected. Functional enrichment analysis indicated that regulation of vasculature development, cell−cell junctions, actin binding and PPAR signaling pathways were mainly enriched. The top 10 hub genes were selected according to the ranking of MCC scores, and 5 genes were closely correlated with OS of LUSC. Additionally, GSEA analysis showed that spliceosome and cell adhesion molecules were associated with the expression of GNG11 and ADCY4, respectively. The GSE30219 and THPA databases and IHC results from the real world indicated that although GNG11 was not detected, ADCY4 was obviously downregulated in LUSC tissues at the mRNA and protein levels. Conclusions This analysis showed that survival-related hub genes are highly correlated to the tumorigenesis and development of LUSC. Additionally, ADCY4 is a candidate therapeutic and prognostic biomarker of LUSC.


In its native state, cellulose is characterized by a high degree of polymerization (DP) and, like most fibrous materials, good tensile properties. However, these characteristics are influenced by several chemical and physico-chemical processes. Some heterogenous degradation phenomena have been investigated in this study by evaluating the effect of light, temperature and acid hydrolysis on two cellulosic materials: flax and cotton. Both separate and combined effects were studied. The degradation reactions, which were evaluated by determining intrinsic viscosity values, develop in two steps at different rates. The possible relation between kinetics and yarn tensile properties were also investigated and are of importance in extrapolating useful indications on the future life time of the art object and on the use of consolidation which is an appropriate conservative intervention before lining becomes really necessary.


Although family life has an important impact on children's life chances, the mechanisms through which parents transmit advantages are imperfectly understood. An ethnographic data set of white children and black children approximately 10 years old shows the effects of social class on interactions inside the home. Middle-class parents engage in concerted cultivation by attempting to foster children's talents through organized leisure activities and extensive reasoning. Working-class and poor parents engage in the accomplishment of natural growth, providing the conditions under which children can grow but leaving leisure activities to children themselves. These parents also use directives rather than reasoning. Middle-class children, both white and black, gain an emerging sense of entitlement from their family life. Race had much less impact than social class. Also, differences in a cultural logic of childrearing gave parents and their children differential resources to draw on in their interactions with professionals and other adults outside the home. Middle-class children gained individually insignificant but cumulatively important advantages. Working-class and poor children did not display the same sense of entitlement or advantages. Some areas of family life appeared exempt from the effects of social class, however.


Abstract Corn (Zea mays L.) is a major source of nutrition for humans and animals. Chemical and physical properties of corn endosperm vary among hybrids, are influenced by genotype and environment, and may affect the crop's response to nitrogen (N) fertilization. The objective of the study was to measure the responses of grain yield and grain N, phosphorus (P), potassium (K), calcium (Ca), magnesium (Mg), manganese (Mn), iron (Fe), boron (B), zinc (Zn,) and copper (Cu) concentration of different endosperm types to N fertilization. The study was conducted at two Ohio locations in 1988, where six endosperm types and two N rates (34 and 200 kg N/ha) were combined in a split plot arrangement. Nitrogen rate (main plots) had little effect on yield at either location, and the soft endosperm hybrid was the only hybrid to respond to N fertilizer. Within fertilizer level, hybrids differed in grain yield with the waxy hybrid out yielding the normal endosperm hybrid, and the hard endosperm hybrid out yielding the sof...


This thesis explores the construction of queer feminine identities and desires in Amsterdam and Berlin in the two decades after 1918. Centralising textual narratives that focused on queer feminine women, this thesis attempts to redress the dearth of research on female-bodied femininities within queer historical narratives and shed new light on experiences that have traditionally been elided from discussions about the queer past. Framed by the thinking of queer philosophers and historians such as Michel Foucault, Eve Sedgwick, and Laura Doan, this thesis employs queer historical methods to adjust the gendered lens of analysis across multiple discursive sites.

Given the intensified interest in labelling desires at the end of the nineteenth century, the first section of this thesis plots the ways in which queer feminine women became available as objects of study in sexological writing about female same-sex desires. The chief focus of my analysis concerns the ways in which women in Berlin and Amsterdam became "present as subjects" through textual productions published for and about queer citizens in the German periodicals Die Freundin (1924-1933) and Frauenliebe (1926-1932) and the Dutch periodicals Wij (1932) and Levensrecht (1940-1947).

The second part of this analysis will concern the dialogues that existed between medico-social discourses and queer literature. Looking first at the feminine "object" in Eva Raedt-de Canter's Internaat (1930) and Christa Winsloe's Das Madchen Manuela (1933), this comparison will focus on the role of "mother-love" as well as protagonists' own constructions of identity and desire. The final comparison will consider the ways in which maternalism is positioned as a specifically erotic concept to explore love between women in Anna Elisabet Weirauch's trilogy Der Skorpion (1919-1931) and Josine Reuling's Terug naar het eiland (1937). Examining the ways that the feminine woman is positioned as desiring subject and desired object in their novels, this thesis suggests that these narratives carve a space for queer "non-lesbian" subjects.


This paper presents a new compression technique based on vector quantization. The proposed encoding algorithm uses a product codebook in which both component codebooks are tree-structured. This allows us to obtain low-complexity progressive encoding of large vectors. We propose a simple, greedy, procedure for the codebook design and assess its performance in the case of gray-scale images for gain-shape product VQ. Simulation results show that the proposed technique exhibits a significant performance gain at very low bit rates, while assuring a satisfactory image quality.


From 2012 to 2015, I was the Principal Investigator on the AHRC-funded project 'Bass Culture in Scottish musical traditions'. One of its aims was to develop an understanding of what goes on underneath the top musical layer in early sources of Scottish music, both in the given basslines, and in the harmonic structures that they imply. Over eighteen months, Karen McAulay and I travelled to libraries to look at printed sources of fiddle music in Scotland, and examined over 300 substantial items. We took the decision not to attempt to examine manuscript sources, which give a more personalised picture both of musical practice and of music education, for mostly practical reasons; by concentrating on printed sources it was possible to survey and catalogue all of the available material in the time allocated. What had been conceived as rather arbitrary boundary dates of 1750 and 1850 made good sense when we found that the publication history of Robert Bremner's A Collection of Scots Reels began in 1757, and that this was the first book to make use of the simple, four-beat repetitive basses that predominate in the sources for over a hundred years. By the second half of the nineteenth century, many sources simply anthologised and adapted material that had already appeared, and indeed a fair number of post-1850 volumes, such as those of James Scott Skinner and James Kerr, remain in print today. We have compiled a database of all the sources seen, available at www.hms.scot, along with digitised images and metadata from a selection.1 This article describes the diversity of content and context that is to be found in the printed sources, before going on to analyse some of the musical transformations and interpretations that take place there. In particular, it discusses the effect of the printed basslines on the character of the tune 'Invercald's Rant' in early sources, and on the music in publications by Niel Gow and William Marshall.


We consider basic algebraic constructions associated with an abstract pre-operad, such as a ⌣-algebra, total composition •, pre-coboundary operator δ and tribrac {h, f, g}. A derivation deviation of the pre-coboundary operator over the tribraces is calculated in terms of the ⌣-multiplication and total composition.


Objective To investigate the value of cardic troponin T(cTnT) in the observation and prognosis estimation in patients with viral Myocarditis(VMC).Methods Serum cTnT was detected in 102 patients with acute viral myocarditis.102 patients were divided into cTnT positive group(n=46,group 1) and negative group(n=56,group 2).All patients were performed with echocardiography and electrocardiograph(ECG).Results There were significant differences in heart function between group 1 and group 2(CI,E/A,LVEDd,P0.05);The normal rate of ECG in group 1 was significantly lower than group 2(P0.05),but the overlapping abnormity rate was markedly higher(P0.005).The cure rate of group 1 was significantly lower than group 2 in 3 months(P0.005).Conclusion The heart function of positive group was lower than the negative group.Cadic damage in positive group were more severe than in negative group.cTnT plays an impotant role in observationg and prognosis estimation in patients with viral Myocarditis.


The changes in the biochemistry of different varieties of iced fish dming transportation in thermocole lined second hand teachests from Veraval to Bombay and Delhi are dis cussed. The moisture increased for all the varieties except for eel and hilsa at Bombay. TMAN and TVN increased in all cases. Maximum increase of TMAN and TVN was observed in seer fish.


The invention discloses a prefabricated assembled light steel fire-proof composite floor structure. A light concrete pavement is poured on an autoclaved aerated concrete slab layer which is formed by same autoclaved aerated concrete slabs in a splicing mode, and distributed steel bars are arranged at connection positions of the upper surface of the autoclaved aerated concrete slab layer; a cold formed steel joist layer is composed of cold formed steel joists arranged in parallel at intervals and vertically and fixedly connected with the autoclaved aerated concrete slab layer; a fire-proof suspended ceiling is fixedly arranged in the arrangement direction of the cold formed steel joists, comprises fire-proof suspended ceiling battens and fire-proof suspended ceiling plates and further comprises fire-proof and heat insulation cotton felts, and the fire-proof and heat insulation cotton felts are located on the two sides of the cold formed steel joists and fixedly connected with the fire-proof suspended ceiling. Except the light concrete pavement, all the other parts can be prefabricated in a factory, spliced on site and reliable in connection, construction speed is high, and a great deal of light energy-saving environmental-friendly material is adopted for the composite floor structure. The composite floor structure is light in self weight and small in steel consumption, has the advantages of heat preservation, sound insulation and fire resistance and is suitable for floor systems of multi-story buildings and high-rise buildings.


A variety of wave phenomena are analyzed and discussed for systems in which chemical reactions and transport take place. Certain families of wave solutions of reaction‐transport equations arise owing to the weak stability of a reference state to a class of perturbations. We consider both wave induction by heterogeneities and autonomous waves and seek perturbation solutions which provide the dispersion relation and the wave vector dependence of the amplitude for one‐parameter families of waves characterized by the wave vector. For the case of an arbitrary reaction mechanism possessing a homogeneous steady state we derive, by use of bifurcation theory and frequency renormalization, small amplitude autonomous plane waves and standing and rotating waves. We find solutions corresponding to long wavelength waves, static structures, and phenomena existing only at intermediate frequencies and wavelengths. The theory is found to have a nonuniformity in convergence in the core region of pacemaker and spiral‐like so...


Small interfering RNAs (siRNAs) have the potential to treat a broad range of diseases. siRNAs need to be extensively chemically modi fi ed to improve their bioavailability, safety, and stability in vivo . However, chemical modi fi cations variably impact target silencing for different siRNA sequences, making the activity of chemically modi fi ed siRNA dif fi cult to predict. Here, we systematically evaluated the impact of 3 0 terminal modi fi cations (2 0 - O -methyl versus 2 0 - fl uoro) on guide strands of different length and showed that 3 0 terminal 2 0 - O -methyl modi- fi cation negatively impacts activity for >60% of siRNA sequences tested but only in the context of 20- and not 19- or 21-nt-long guide strands. These results indicate that sequence, modi fi cation pattern, and structure may cooperatively affect target silencing. Interestingly, the introduction of an extra 2 0 - fl uoro modi fi cation in the seed region at guide strand position 5, but not 7, may partially compensate for the negative impact of 3 0 terminal 2 0 - O -methyl modi fi cation. Molecular modeling analysis suggests that 2 0 - O -methyl modi fi cation may impair guide strand interactions within the PAZ domain of argo-naute-2, which may affect target recognition and cleavage, speci fi cally when guide strands are 20-nt long. Our fi ndings emphasize the complex nature of modi fi and HTT_10150 by enhancing seed-based (i.e., guide strand positions 2 target recognition.


An automated, on-the-go, soil nitrate monitoring system (NMS) was built and tested, making use of a nitrate
ion selective electrode which offers a convenient and quick method for in-field soil nitrate measurement. The system
consists of a soil sampler which collects a representative soil sample at regular intervals, a soil metering and conveying
unit which meters a known amount of soil into an extraction unit, a nitrate extraction unit, which extracts the soil nitrate
using deionized water, and analyzes for nitrate using an Orion nitrate ion selective electrode(ISE), and an electronic
control unit that measures nitrate concentration and provides the control signals to operate the system. The overall
operation of the system was controlled using a Micromint BCC52 computer. A field calibration process was used to enable
prediction of soil nitrate levels within 10 s after soil sampling. Results from lab testing indicate that for a silty clay loam
soil, the actual, or final nitrate level could be predicted with 95% accuracy after 6 s of measurement.


Total knee arthroplasty is a major surgical procedure that can result in significant pain during recovery. Adequate analgesia is, therefore, the cornerstone in enabling good functional outcomes for the patient. Our study assessed retrospectively, the post-operative pain scores with continuous proximal adductor canal nerve block catheter with and without posterior capsular infiltration. Materials and Methods: All patients undergoing unilateral robotic total knee arthroplasty were randomized into two groups. One group received only a continuous adductor canal nerve block catheter. The other group was provided with a continuous adductor canal nerve block catheter with posterior capsular infiltration. The post-operative VAS (Visual Analogue Scale) score and the time of the first rescue analgesic were noted. Results: The group which received continuous adductor canal nerve block catheter with posterior capsular infiltration had better post-operative analgesia with delayed time of first rescue analgesia. Hence local anaesthetic infiltration in the posterior capsule provided superior recovery rates in terms of pain management. Conclusion: Our study concluded that patients receiving continuous adductor canal catheters and posterior capsular infiltration had better post-operative analgesia than those receiving only continuous adductor canal catheters. This aided in faster recovery and mobilization in robotic knee arthroplasty, contributing to fast-tracking.


The Turkey Energy Liberalization Project aims to improve supply security and reform state-owned energy generation business by rehabilitating the Afsin-Elbistan A Thermal Power Plant. This environmental assessment summary briefly identifies environmental risks connected with the project and discusses measures to mitigate them. Among the suggestions the following are offered. Minimize dust emissions from land clearing, drilling and blasting, ground excavation, cut and fill operations, facility construction, and from equipment traffic over temporary roads at the construction site by using the following methods: Cover stockpiled material with suitable sheet material; sprinkle water on access roads, limit vehicle speed, cover vehicles, and maintain equipment and machinery. Mix ash with gypsum and convey to mining disposal area. Treat wastewater from workers before discharge to river bodies, and monitor groundwater quality. Solid waste from the personnel, medical wastes, and oily wastes, hazardous wastes such as used batteries, bitumen, cables, copper, fire-fighting foam, adhesives, general chemicals, acids, oil rags and absorbents, solvents, contaminated soils, insulation, paint sludge, used oil and paint cans and drums etc. and package wastes will be collected at black bags separated from medical, hazardous, dangerous and package wastes. Separately collected domestic wastes will be transported to temporary waste storage center or container by special vehicles and stored separately. Store recyclable wastes in different closed containers. Segregate paper, cardboards, plastics and metal package wastes according to their type and collected by blue bags. Handle other, including hazardous and medical, waste according to regulation. To control noise, restrict hours of operation and ensure vehicle noise does not exceed stated levels. To minimize industrial accidents, train personnel in health and safety issues, have workers wear protective equipment, set up health center on site, and use fire prevention measures.