Since the 21st century,reform in China has kept going on.How to realize the goal "Building a well-off society in an all-round way" proposed at the 16th National Congress of Communist Party of China(16th NCCPC),and how to explore the potential of economy have become one of the most difficult issues for the government of China.In recent years,the central government has taken measures to support the rural area,to develop agriculture,and to raise the income of the farmers.Meanwhile,some experts come up with the idea of reforming the rural land system to realize land marketization and agricultural scale management."Land Circulation" is also on the schedule.The writer of the present paper analyzes the possibility of land circulation and suggests that the process of land circulation should refer to the successful experience on land reform from other countries,to make sure that the policy of land circulation goes on successfully.


We study the large‐time behaviour of the fundamental solution of parabolic equations with an elliptic part being non‐local convolution‐type operator. We assume that this operator is a generator of a Markov jump process, and that its convolution kernel decays at least exponentially at infinity. The fundamental solution shows rather different asymptotic behaviour depending on whether |x|≲t , or t≪|x|≪t , or |x|∼t , or |x|≫t . In each of these regions we obtain sharp pointwise estimates for the fundamental solution.


The citizen participation is the process through which the preoccupations, needs and values of the citizens are incorporated in the decisional process of local public administration. There are two directions of communication (between citizens and administration), with the general purpose of making better decisions (local public administration) sustained by the citizens, on the basis of the attributes their satisfaction develops on. Both Upson 763 and Schachter plead for the implication of the citizens in the act of governing. The problem they notice is given by the difficulty of implication of the citizens in public affair problems. After Schachter, the indirect benefits associated with the involvement of citizens in the administrative act are: economical development, community reviving, perception of safeness, low mobility of the citizens with low salaries. Stone 764 fights Schachter's ideas through the prism of plural wishes, expectations and opinions of citizens which mainly cannot be transform into efficient results for the governing act. Even though, Schachter himself admits the fact that the same project can be efficient or not, depending on what that community has been waiting for. In conclusion, it is difficult for the leaders of a community to decide which project should be implemented, because the results can be labelled as efficient or not depending on the subjective criteria each individual has. With such a big emphasis on the conformity of the administration's results to the citizens' expectations, Schachter misses the fact that the citizens' expectations can be unrealistic in what efficiency is concerned 765 . Ebdon and Franklin 766 claim that the instruction of citizens with respect to fiscal aspects with which they operate in public system, helps them to separate the feasible projects from the unfeasible one. When Upson talks about the implication of citizens in problems of efficiency he distinguishes between "how" and "what" the public administration does. Upson argues that because this two situations interact with each other, the civil servants have to pay attention to


The performance of a solar cell is affected by pinhole formation during the deposition of the very thin cadmium sulfide (CdS) film. Insertion of a zinc oxide (ZnO) buffer layer between the top tran...


ABSTRACT To satisfy the resilient requirements, a novel dual-self-centering variable friction damper (DSC-VFD) brace with self-centering variable friction damper systems and basalt fiber-reinforced polymer tendons, is proposed. The working mechanism of the DSC-VFD brace was first investigated. Then, four DSC-VFD and SC-VFD braces with different groove angles were designed, and quasi-static experiments were conducted. Finally, finite element models of the DSC-VFD braced frame were created and the seismic responses of the frames were analyzed. The results show that the DSC-VFD brace presents a novel flag shape with large post-yield stiffness and enhanced energy dissipation which can effectively control the structural responses.


Infarct core assessment on presentation is important to evaluate salvageable tissue to select patients for thrombectomy. Our study aims to evaluate the correlation between infarct core volume measured by computed tomography (CT) perfusion (CTP) and magnetic resonance diffusion‐weighted imaging (MR‐DWI) in patients with acute large‐vessel occlusion.


This paper describes an experimental search for large streamwise vortices in a turbulent wall jet flowing over a convex surface. The existence of these vortices resulting from a centrifugal instability was suspected but never previously observed in this flow. They eluded detection because they meander across the span, as they become larger, with increasing distance from the nozzle. A particle image velocimeter, used in air, enabled the mapping of these vortices establishing their circulation and their evolution in the direction of streaming. Although the longitudinal structures educed do not contribute to mean spanwise distortion of the flow, they are strong enough to augment the Reynolds stresses that increase the rate of spread of the jet and its turbulent intensities. Since the temporal resolution of the instrument is not yet adequate to track the motion of large vortices, the turbulent characteristics surrounding a pair of educed counter-rotating vortices were observed in a frame of reference that is ...


Upheaval buckling of pipelines caused by thermal- and pressure-induced loading is an important issue in pipeline design. The uplift capacity of pipelines is determined by the pipe–soil interaction during pipeline upheaval in soil. Pipelines to be installed in soft clay are usually placed into trenches and then backfilled. In this paper, a set of test devices were developed and a series of full-scale model tests were carried out on a pipe segment buried in lumpy soft clay backfill, including backfilling tests, load-controlled uplift tests, and a displacement-controlled test. Eight total pressure transducers were embedded in the wall of the pipe segment to measure soil pressures on the pipe segment, and five linear variable differential displacement transducers (LVDTs) were arranged to record the vertical displacement of the pipe segment and the surface of the soft clay ground. The stabilizing force keeping the pipe segment in place during the backfilling process was found to fit a nearly linear relationshi...


Type of funding sources: None.

 Orthotopic heart transplantation (OHT) is a standard treatment option for end-stage heart failure (HF). Although post-transplant diabetes (PTDM) is a main complication due to immunosuppressive corticosteroid treatment, its impact on left ventricular (LV) function following OHT has not been described.

 The purpose of this study was to analyse the possible effect of PTDM on LV function in OHT patients using conventional and speckle tracking echocardiography. Furthermore, this study aimed to compare echocardiographic LV function parameters to clinical parameters, including heart rate, blood pressure, and Hemoglobin A1C (HbA1c) in OHT recipients with or without PTDM.

 We performed a retrospective study including 77 (59 males) OHT patients (PTDM n = 29) using data from the routine 3-year follow-up. The mean age of the study population was 52 ± 14 years. All patients were examined using 2-dimensional transthoracic echocardiography with an ultrasound system equipped with a S5-1 transducer. Systolic-, diastolic blood pressure, heart rate, and HbA1c levels were recorded in conjunction with the TTE examination for each participant.

 Participants with PTDM had impaired LV function measured by global longitudinal strain (LVGLS), increased septum diameter, and a lower diastolic EA-ratio compared to the non- PTDM patients. Additionally, a significant correlation between high HbA1c levels and poor LVGLS was detected.

 We found that subtle LV dysfunction, including remodeling of the heart (i.e., increased wall thickness), reduced longitudinal contractile function, and altered diastolic function, was present in OHT patients with PTDM. Our findings suggest that sub-clinical myocardial dysfunction in OHT patients with PTDM is progressive and may evolve to clinical LV dysfunction and HF. Hence, analyzing secondary cardiac effects of PTDM in OHT patients have a therapeutic and prognostic value and may influence long-term patient survival. Abstract Figure.


In order to strengthen the effectiveness of building materials experimental teaching, this paper based on the teaching content, teaching methods, evaluation system of these three levels of experimental teaching reform, and then summed up a more practical experimental teaching mode. Based on the trend of less class hours and more course content of building materials experiment course, two experimental teaching contents, including design and experiment, are integrated to improve and perfect the old teaching methods, so as to stimulate students' learning enthusiasm, improve students' practical skills, operation skills, innovation skills and the innovation ability to solve similar problems in the


Spatial and temporal variations in the intensity of subsurface denitrification in the water-column of the eastem Arabian Sea have been investigated using chemical and isotopic proxies. The data show a steady increase in the denitrification intensity from ∼10 ka to ∼2 ka BP, probably caused by changes in surface productivity fuelled by strengthening of upwelling (monsoonal intensity). In addition, changes in redox conditions and detrital material input are assessed using abundances of a suite of major and trace elements. The temporal variations in some of the monsoonal proxies are characterized by periodicities of ∼1400 and ∼700 years, similar to those reported in the South Asian (Chinese) monsoon and high-latitude climate (north Atlantic region).


Practical teaching is an important part of the whole teaching system of Non-destructive Testing Specialty in Vocational education, and the cultivation of practical ability is an important part of Vocational education. This paper analyses the characteristics of practical teaching of Non-destructive Testing Specialty in Vocational education. On the basis of constructing the content system of practical teaching, it puts forward the concrete methods of implementing the practical teaching system. Keywords-vocational education non-destructive testing


The Ethiopian government is implementing mega projects to achieve a five years transformation and growth plan and Commercial Bank of Ethiopia is expected to mobilize a huge amount of deposit and foreign currency for the projects. However, in Ethiopia, banks mobilized small amount of deposit, 11.6%. This initiated for an assessment of determinants of mobilization of deposits in CBE. The study used a cross-sectional design by collecting financial data of the years 19812012 on the independent variables (Income, expense, asset, liability, reserve, loans and advances and consumer price index). Descriptive and econometric analyses are done by using E-views 5and Excel 2007. The study identified that CBE's main source of capital is deposit; demand deposit remained to be dominant; the bank's total deposit is related positively with income, its asset, liability, its loans and advances granted and Consumer Price Index. However, the bank's deposit is negatively related to its reserve requirement and its expense. Also, almost by 25% all the endogenous variables will affect a one year lag in the short run to reach the equilibriums position in the long run. Then, it is recommended that there is a need to remove obstacles on the depositing road by awareness creation efforts tailored to its employees, stakeholders and customers; improving bank service accessibility and consumption.


This study aims to determine the role of education on employee career development at the Aceh Manpower and Population Mobility Service. population of employees at the Aceh Manpower and Mobility Department as respondents. The data analyzed in this study is primary data in the form of questionnaire circulation. The data is then processed through multiple linear regression analysis with the help of SPSS. The objects in this study are the facilities, individual abilities, and efforts of the independent variables. performance. The results of this study identify that simultaneously, the variables of Education and Training on the Career Development of Employees at the Aceh Manpower and Population Mobility t-test. The results of the study on the education and training variable (X) obtained tcount = 34,356 while ttable 2,086, the results of this calculation indicate that tcount > ttable with a significance level of 0.000 or the probability is far below = 5%. Thus, the results of statistical calculations show that partially the education and training variables play a significant role in increasing the career development of employees at the Aceh Manpower and Population Mobility Service. Aceh Manpower and Population Mobility Service.


The aim of this paper is to increase knowledge and understanding on how the implementation of language content through specialized software, such as the "Integrated Intelligent Learning Environment for Reading and Writing-iLearnRW", can enhance learning during intervention procedures to enhance reading skills for children with dyslexia.The iLearnRW software is a newly designed tool that makes use of innovative technology and provides individualized intervention through games that incorporate learning activities, addressing those language areas that are most challenging for children with dyslexia in a highly entertaining and motivating way. Individualized intervention is provided through an underlying user profile, which incorporates these language features and is constantly updated as the child uses the software playing games, presenting language material selected based on his difficulties and recording his progress. A group of 78 students (52 male, 26 female) diagnosed with dyslexia, aged between 9 and 11 years old, was assessed for phonological, morphological and vocabulary skills. The students logged in the iLearnRW software on a mean of 14.18 days over a six-month intervention. After the 6-month intervention, the students were assessed once again on the same skills so as to establish the tool's effectiveness.The results' analysis revealed the following: (i) there was a strong constructional linkage between the profile entries of the sample, the language content of the tasks of the screening test as well of the games and its effectiveness in the students' performance; (ii) the students who received specific guidance by their teachers, obtained higher success rates in most of the games than the students without any guidance, and (iii) the quantity of the language content and the time playing were not correlated with the students' performance in the software's games. Keywords: Digital technology, assistive computer software, dyslexia, learning environment


AIntroduction With the prevailing complex emergency that many developing countries are witnessing, it is significant to understand the different actors in wars and reconstruction, since players in the war arena when compared to those during the WWII, new actors are being discovered in the field, making the situation complicated and challenging to relief and development organization, especially in the context of post war reconstruction. With the new situation one wonders; what is the relationship between relief and development in post conflict reconstruction? Therefore, there is a need to highlight the vital relationship among relief and development, explaining barriers that face the integration of both from the literature perspective, questioning whether the literature was adequate when related to this field or not.


Surgical Techniques. Indications and Outcomes of Filtration Surgery. Surgical Anatomy. Modern Anesthetic Techniques. Modern Anti-Fibroblastic Therapy. How to do a Trabeculectomy. How to do Non-penetrating Surgery. How to insert a Seton. Seton Surgery: Management and Complications. How to Insert a Pars Plana Seton. How to do Full Thickness Surgery/Subscleral Scheie. How to do a Surgical Peripheral Iridectomy. How to do Combined Cataract/Trabeculectomy. The UBM in Glaucoma Surgery. Management of Complications. Overview: How to Think about and Manage Complications. Massage: Techniques and Complications. Suture Lysis: Techniques and Complications. Releasable/Adjustable Sutures. The Failing Bleb: Risk Factors and Diagnosis. Encapsulated Bleb: Diagnosis and Management. The Flat Bleb: Flap Needling and Management. Suprachoroidal Hemorrhage: Diagnosis and Management. Malignant Glaucoma: Diagnosis and Management. Management of the Leaking Bleb. Management of Large Over Filtering and Corneal Blebs. Flat Chamber with Choroidal Effusion: Diagnosis and Management. Prevention and Management of Hypotonous Maculopathy. Blebiis and Endophthalmitis: Diagnosis and Management Post-Trabeculectomy


Two thousand one hundred and nineteen bovines belonging to 156 dairy herds distributed among 22 counties in Passo Fundo, RS, were tested for bovine tuberculosis (BT) and bovine brucellosis (BB). The prevalence of antibodies to bovine viral diarrhea virus (BVDV), enzootic bovine leukemia virus (BLV) and bovine herpesvirus (BHV-1) was estimated by random sampling in 28 properties; considering a prevalence of infection of at least 30% and a confidence interval of 90%, 204 serum samples were tested. Among de 2119 bovines, 32 (1.51%) were positive for TB and 26 (1.22%) were positive for BB. The serological tests of the animals belonging to the 28 herds indicated the presence of antibodies to BHV-1, BVDV and BLV in 22 (92.35%), 19 (67.35%) and 17 (60.71%) herds, respectively; 11 (39.28%) properties had animals positive to BHV-1, BVDV and BLV, and in only 1 (3.57%) herd all animals tested were negative to these infections.


The present invention relates to passenger guidance system. The system includes a means for transmitting and means for generating call data (8), the call data of the one or more elevator column group control system (7) and (8). The above-mentioned group control system, the group call data to process the call data; to generate a (8 8b), the group call data; to deliver the (8 8b) to the elevator column of the elevator control means (3). This guidance system includes a display device (1), this device, group call data for one or more of the group control system; used to display the (8 8b).


The editor notes that when he accepted the position of Editor of the GAP Newsletter he had little or no concept of what the job entailed. In fact he had no idea of what place the Newsletter had in our professional Lives. A note from his predecessor Wolf Kummer indicated that the purpose of the Newsletter is to disseminate information of non-archival value to members of the group. While the editor deems this a worthwhile purpose he would like the Newsletter to be something more, something better.


Effective insect pest monitoring is a vital component of Integrated Pest Management (IPM) strategies. It helps to support crop productivity while minimising the need for plant protection products. In recent years, many researchers have considered the integration of intelligence into such systems in the context of the Smart Agriculture research agenda. This paper describes the development of a smart pest monitoring system, developed in accordance with specific requirements associated with the agricultural sector. The proposed system is a low-cost smart insect trap, for use in orchards, that detects specific insect species that are detrimental to fruit quality. The system helps to identify the invasive insect, Brown Marmorated Stink Bug (BMSB) or Halyomorpha halys (HH) using a Microcontroller Unit-based edge device comprising of an Internet of Things enabled, resource-constrained image acquisition and processing system. It is used to execute our proposed lightweight image analysis algorithm and Convolutional Neural Network (CNN) model for insect detection and classification, respectively. The prototype device is currently deployed in an orchard in Italy. The preliminary experimental results show over 70 percent of accuracy in BMSB classification on our custom-built dataset, demonstrating the proposed system feasibility and effectiveness in monitoring this invasive insect species.


The frequency of expression of the mylohyoid bridge was studied in the skeletal remains of 122 Pre-Columbian Peruvians. The incidence in this population was found to be 17.6% as compared to an incidence of 15.4% found in a similar size sample population of American Negroes and a 16.1% incidence in a population of American Whites from the Terry Collection. No significant differences as to the incidence of the mylohyoid bridge were found as to the side of occurrence or between deformed and undeformed crania. A mylohyoid bridge was found in a younger individual (6 years) than had previously been reported. Females showed a significantly higher incidence of this trait in all three populations studied. A similar incidence of the mylohyoid bridge in Pre-Columbian and Mongoloid peoples adds support to the theory of a Mongoloid origin of these people. The mylohyoid bridge is considered to be a significant genetic marker which along with other such markers could be of value in population studies.


Ubiquitous computing technologies enable capturing large amounts of human behavioral data. The digital footprints computed from these datasets provide information for the st udy of social dynamics, including social networks and mobility patterns, key elements for the effective modeling of virus spreading. Traditional epidemiologic models do not consider individual information and hence have limited ability to capture the inherent complexity of the disease spreading process. In this paper w e propose an agent-based system that uses social interaction s and individual mobility patterns extracted from call detail re cords to accurately model virus spreading. The proposed approachis applied to study the 2009 H1N1 outbreak in Mexico.


—As we go further into this century, the questions surrounding data and privacy are going to get more prominent and harder to answer. There has already been substantial outcry regarding misuse of private data by corporations around the world. This has exacerbated the need for machine learning methods which ensure data privacy. One of the major cause of such concerns are the small devices that many individuals use in their everyday lives. These devices can range from a virtual assistant like Amazon's Alexa to a self-driving car. There are long-standing concerns around corporations listening to your conversations and monetizing them, all done in the name of improving their products. In this paper, we introduce FLADS , a tool which combines Federated Learning concepts with an Asynchronous Distributed System to create a network of node which don't communicate with any centralized server. Rather, they facilitate learning by sharing their data among themselves. FLADS is novel in that it proposes a trade-off between accuracy and training throughput by allowing for stale gradients. It also combines the modules of federated learning and distributed systems in a plug-and-play way; any of the algorithms can be independently changed and plugged to our implementation provided they follow the interface. We also run experiments to quantify how well FLADS performs and the trade-offs it offers. From the experiments, we conclude that allowing for stale gradients can improve overall model training throughput with only marginal impacts to accuracy, and may even improve accuracy in a very skewed data distribution.


The expression form,style,and basic features of Maya painting art are analyzed,and its cultural tokens are deeply researched,in order to enable people to learn more about the art's characteristics and its deep historic connotation.


Abstract : The implications of Segletes' recent equation of state are examined, when idealized to the condition defined as quasi-harmonicity. Results indicate that at large volumetric strains, a proportionality no longer holds, in general, between the volumetric and vibrational stiffnesses. The governing relation between these two stiffnesses is presented and is a function of the characteristic frequency of the lattice, alternately expressed in terms of the lattice spacing. It is further shown that the quasi-harmonic idealization of Segletes' equation will approach the harmonic approximation in the limit.


Abstract The pretrial detention decision has critical implications for a defendant's employment opportunities, family ties, likelihood of conviction, and length of prison sentence. While prior researchers have assessed the disparities that exist in the bail decision based on defendant and case characteristics, little systematic empirical attention has been paid to the effects of the pretrial detention judge on decisions at this stage of criminal case proceedings. Here, we focus specifically on judge race and sex, exploring not only the unconditional effects of judge sex and race but also whether the effects of these judge characteristics at the bail decision are conditioned on the sex and race of the defendant. Using newly collected pretrial detention data from 22 federal district courts from 2003 to 2013, we empirically examine the effects of judge and defendant race and sex on whether defendants are released on their own recognizance before trial or, instead, are given a more punitive pretrial outcome. Our results indicate important judge and defendant-based differences in bail setting leniency provided to defendants including that Black judges are more likely to grant pretrial release without hefty conditions to white defendants than are white judges. We also find that female judges are more likely to detain or require monetary bail for male defendants and less likely to do so for female defendants relative to male judges.


Abstract Simulations of glacier evolution are needed to assess future changes in the runoff regime of mountain catchments. A simplified parameterized model is applied here to simulate future thickness changes and glacier retreat of Mer de Glace, French Alps. A normalized thickness change function describing the spatial distribution of surface-elevation changes as a function of elevation has been determined. The model reveals that under present climatic conditions Mer de Glace will continue to shrink dramatically in the coming decades, retreating by 1200 m between now and 2040. The method has certain limitations related to the uncertainties of the normalized function based on thickness change data. An error of 10% in the normalized function leads to uncertainties of 46%, 30% and 18% in Mer de Glace front, surface area and glacier-wide mass-balance changes respectively in 2040. Because the difference of the normalized function largely exceeds 10% from one glacier to another, even within a given glacier size class and elevation range, it would be very risky to extrapolate the normalized function to unmeasured glaciers. Consequently, the method is applicable only on glaciers where past surface elevation changes are well constrained.


Asynchronous pipelines offer advantages of flexibility and modularity over synchronous pipelines. In this work, the AES-128 encryption algorithm was implemented using the MOUSETRAP asynchronous pipelining technique. MOUSETRAP allows easy integration with existing standard-cell based design methodologies. Combinational logic blocks were implemented using automatic synthesis tools, while sequential elements of the pipeline were designed by hand. This work was able to achieve a maximum throughput of 312.5 million operations/sec, a latency of 14.374 ns, and average power of 91.38 mW at maximum throughput using 65-nm standard-cell CMOS technology.


Background Tisotumab vedotin (TV) is an investigational antibody-drug conjugate composed of a tissue factor (TF)-directed human monoclonal antibody covalently linked to the microtubule-disrupting agent monomethyl auristatin E (MMAE) via a protease-cleavable linker. TV demonstrated single agent activity (24% objective response rate [ORR]) in previously treated recurrent or metastatic cervical cancer (NCT03438396) where currently, there is no standard of care and ORRs are typically less than 15% and often of limited duration.1–8 TV is currently being evaluated in combination with pembrolizumab (PD-1 inhibitor), bevacizumab, or carboplatin in cervical cancer (NCT03786081), or as a monotherapy in multiple other solid tumors (NCT03913741, NCT03485209, NCT03657043). The anti-tumor activity of TV may be multimodal as TV can induce tumor cell death through several mechanisms, including direct and bystander MMAE-mediated cytotoxicity, as well as antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), and immunogenic cell death (ICD)].9 10 To better characterize immune-mediated tumor cell killing by TV and further the rationale for combination with pembrolizumab, we set out to refine our understanding of TV-mediated ICD and subsequent immunomodulatory effects. Methods We evaluated the ability of TV to mediate activation of immune cells in vitro using co-cultures of TF-expressing tumor cells and human peripheral blood mononuclear cells (PBMCs). We also assessed the ability of TV to induce recruitment of innate immune cells to tumors in vivo using a TF-expressing xenograft tumor model. Results In vitro, tumor cells treated with TV showed several hallmarks of immunogenic cell death, including markers of endoplasmic reticulum (ER) stress and release of ATP and high mobility group protein B1 (HMGB1). Co-culture of TV-killed tumor cells with allogeneic human PBMCs led to innate immune cell activation (measured by upregulation of the costimulatory molecule CD86) and T cell proliferation. Combination with PD-1 blockade further amplified the immune response, leading to enhanced T cell proliferation and cytokine production. Moreover, in vivo studies demonstrated that TV treatment led to recruitment of F4/80+ and CD11c+ innate immune cells to xenograft tumors. Conclusions These data show that, in preclinical models, TV induces immunogenic tumor cell death, which can promote activation and recruitment of immune cells to the tumor. The totality of in vitro and in vivo data provides evidence for the immunomodulatory effects of TV and bolsters rationale for combining TV with immune checkpoint agents. Ongoing analyses aim at further characterizing the immune response induced by TV in preclinical models and patients. Acknowledgements We would like to thank Kristen Gahnberg for embedding and sectioning tissues for these studies and Anthony Cao for his early work identifying hallmarks of ICD in response to TV treatment in vitro.9 Ethics Approval Animals studies were approved by and conducted in accordance with Seattle Genetics Institutional Care and Use Committee protocol #SGE-029. Consent N/A References Van den berg YW, Osanto S, Reitsma PH, Versteeg HH. The relationship between tissue factor and cancer progression: insights from bench and bedside. Blood 2012;119(4):924–932. Miller DS, Blessing JA, Bodurka DC, Bonebrake AJ, Schorge JO. Evaluation of pemetrexed (Alimta, LY231514) as second line chemotherapy in persistent or recurrent carcinoma of the cervix: a phase II study of the Gynecologic Oncology Group. Gynecol Oncol 2008;110(1):65–70. Bookman MA, Blessing JA, Hanjani P, Herzog TJ, Andersen WA. Topotecan in squamous cell carcinoma of the cervix: A Phase II study of the gynecologic oncology group. Gynecol Oncol 2000;77(3):446–449. Garcia AA, Blessing JA, Vaccarello L, Roman LD. Phase II clinical trial of docetaxel in refractory squamous cell carcinoma of the cervix: a Gynecologic Oncology Group Study. Am J Clin Oncol 2007;30(4):428–431. Monk BJ, Sill MW, Burger RA, Gray HJ, Buekers TE, Roman LD. Phase II trial of bevacizumab in the treatment of persistent or recurrent squamous cell carcinoma of the cervix: a gynecologic oncology group study. J Clin Oncol 2009;27(7):1069–1074. Santin AD, Sill MW, Mcmeekin DS, et al. Phase II trial of cetuximab in the treatment of persistent or recurrent squamous or non-squamous cell carcinoma of the cervix: a gynecologic oncology group study. Gynecol Oncol 2011;122(3):495–500. Schilder RJ, Blessing J, Cohn DE. Evaluation of gemcitabine in previously treated patients with non-squamous cell carcinoma of the cervix: a phase II study of the Gynecologic Oncology Group. Gynecol Oncol 2005;96(1):103–107. Chung HC, Ros W, Delord JP, et al. Efficacy and safety of pembrolizumab in previously treated advanced cervical cancer: results from the phase II KEYNOTE-158 study. J Clin Oncol 2019;37(17):1470–1478. Alley SC, Harris JR, Cao A, et al. Tisotumab vedotin induces antitumor activity through MMAE-Mediated, Fc-Mediated, and Fab-Mediated Effector Functions In Vitro [abstract]. Cancer Res. 2019;79(13 Suppl):Abstract 221. Breij E, de Goeij B, Verploegen S, et al. An antibody-drug conjugate that targets tissue factor exhibits potent therapeutic activity against a broad range of solid tumors. Cancer Res 2014 ;74(4):1214–1226.


At this time of year, when Agag is on Holiday, it has become Traditional to Intercept a Letter from Aunt Mabel to her O.T. Niece in Australia.


A vanishing theorem for numerically connected divisors, first given by Bombieri for surfaces, is established in any dimension. A definition of k-connected divisors is proposed, then such divisors on threefolds are studied.


Prologue: In the fast-paced world of journalism, science writers are a special breed: well-trained, conversant in a wide range of health and medical subjects, and prepared at a moment's notice to translate for readers the meaning of the latest technological breakthrough. In the last year, their calls to action have been Barney Clark, Baby Fae, and, most recently, Bill Schroeder. At the same time, though, they often are viewed within their profession as the backbenchers of big-time journalism, experts in the scientific arcane whose subject matter only occasionally merits page-one attention or prime-time television coverage. What drives these journalists? What pressures are they subjected to as they strive to unravel the mysteries of science for an interested public and advance their own careers? In a landmark study, Jay Winsten, director of the Office of Health Policy Information at the Harvard School of Public Health, set out three years ago to answer these questions in an examination of how news judgment...


Starting from a yeast phenotypic screening performed on 21 chemically different substances we described the discovery of two small molecules as GCN5 inhibitors. The 2-methyl-3carbethoxyquinoline 9 and its 2-desmethyl analogue 18 were able to significantly reduce the yeast cell growth, thus miming the effect of GCN5 deletion mutant. Tested to evaluate their effect on GCN5-dependent transcription of the HIS3 gene, 9 and 18 showed high inhibitory activity of gene transcription, more evident in activated conditions. Compound 9 was also able to reduce the acetylation levels of H3 and, to a lesser extent, H4 in yeast at 0.6 mM. In human leukemia U937 cells, at 1 mM concentration 9 showed 27% apoptosis induction, while 18 had just a little effect in the same conditions. Further studies on 9 and 18 will be performed to deepen their effects on GCN5-related phenomena.


Table of Contents: PART I: COMPARATIVE POLITICS: THEMES AND APPROACHES. 1. The Comparative Study of Politics. PART II: ECONOMIC, CULTURAL, AND IDENTITY STRUCTURES. 2. Economic Class, Development, Systems, and Globalization. 3. Ideas as Structure: Political Culture and Ideology. 4. Identity Structure. PART III: POLITICAL STRUCTURES. 5. Political Systems and Their Rules. 6. Legislatures and Executives. 7. Unelected Components of Government. PART IV: ELITES, MASSES, AND POLITICAL DECISION MAKING. 8. Political Participation and Approaches to Linking Masses and Elites. 9. Political Parties and Electoral Systems. 10. Leadership and the Importance of Individuals in the Political Process. PART V: USING STRUCTURES AND CHOICES TO UNDERSTAND POLITICAL OUTCOMES. 11. Regime Transitions. 12. Public Policy. Epilogue Structured Choices and the Comparative Study of Politics.


Environmental reasons like the greenhouse effect, caused by artificial refrigerants, have risen several items to discuss. The forgotten natural gas R 744 is now in the spotlight again. His thermodynamic properties, multiple purposes and functional range allow the use in different fields of application. This report will reflect the above mentioned items as well as the activities at TWK which include further education in the field of R 744.


Zygmunt Bauman reviews the relationship between modernity and the rationalism in the perspective of Archaeology of Knowledge.He emphasizes on different performances and features of rationalism during different developmental stages of modernity,reveals the affinity relationship between the developmental process of modernity and the evolutive history of rationalism,and demonstrates that the rationalism is the primary factor and driving force during the development of modernity as well as the main reason of modernity as an unfinished project.


: In the present paper, the 1 L twin-blade planetary mixer is selected as the research object, utilizing the CFD method to systematically research the effecting relation of the blade's geometric parameters (blade-blade clearance, helical angle) of the twin-blade planetary mixer on the mixing torque and the power consumption when mixing the Newtonian fluid(corn syrup). The simulation model of the twin-blade planetary mixer is made comparison validation to experimental data, which in turn make sure the results are reliable. The research results show that decreasing the clearance or increasing the helical angle can increase the mixing torque and power consumption of blades. Increasing the helical angle can increase the kneading time, and decreasing the clearance or increasing the helical angle can enhance the kneading strength of blades. Within certain limits, when the clearance c 1 =3.0 mm and the helical angle β k =35°, the average torque of hollow blade reaches the minimum value 0.046 93 N·m; when the clearance c 1 =1.0 mm and the helical angle β k =55°, the average torque of hollow blade reaches the maximum value 0.068 73 N·m. When the twin-blade planetary mixer stirs the Newtonian fluid, the Power number N pM and the Reynolds number R eM show the linear relation, and the effect of clearance on the power characteristic of twin-blade planetary mixer is more notable than the helical angle.


The perfecting in the last years of augmentation lenses and that of the microscopes, as well as the development of samples preparation techniques, provided excellent tools in the several science areas. The evaluations at the microscope, electron or optical, of edible products utilized for ruminants, has helped in the cause/effect relationship understanding in animal performance. Of paramount importance are the advances obtained in the action mode of rumen microorganisms in the substrates knowledge, mainly of the particle-associated bacteria. Advances were also achieved in the knowledge of factors that affect the forage dry matter degradability, especially of the C 3 species, but these advances also contribute to the knowledge of the C 4 . These studies results allowed the establishment of several research lines, creating the possibility of discrimination in the early stages of grasses and legumes selection, those which present the greatest qualitative potential. There is especial merit also in the studies to increase the corn and alfalfa stalk degradability, as well as those to identify how the agricultural byproducts treatment can increase its quality, and to verify the effect of inoculants, such as exogenous enzymes, in the dry matter degradability rate. Besides the verification of the tannin effect, especially in legumes, into the digestibility, which may in the future to foster the utilization of additives that can minimize or prevent their harmful effects on forage consumption. With relation to cereal grains, it may be verified the genotype influence on degradability. The results achieved up to now, give the base for the genetic manipulation of feed stuff utilized by ruminants, which probably will be object of research in the next decades.


This paper shows that in the philosophy of Sanchez Vazquez the basis for creative praxis is not innovation but the activity of practical consciousness, to which that Marxist philosopher describes as dialectical unity of the subjective and the objective. Furthermore, the paper argues that, in the sense of such unity and mutatis mutandi, creation has a place in non-practical human activity.


Accurate and precise measurement of serum creatinine is very important for assessment of kidney function. However, false estimates of serum creatinine have been found due to interference by both exogenous and endogenous substances which have been attributed to factors such as decreased or inhibited tubular secretion of creatinine, interference with serum creatinine assays and increased production of creatinine. Several drugs cause positive and negative interference through these mechanisms resulting in false positive and negative estimates of serum creatinine which may affect glomerular filtration rate (GFR) calculation also. Endogenous substances also affect the creatinine assay systems resulting in false estimate of serum creatinine concentration. Therefore, the awareness about the drug-induced or endogenous substance-induced false estimates of serum creatinine and preanalytical errors in blood sampling is important. Some remedial measures to avoid these interferences are: (i) avoiding blood draws from indwelling catheter, (ii) giving preference to fasting blood specimen and (iii) selecting the suitable analytical method for creatinine estimation (based on the information about the drugs being given to the concerned patient).


Background: Cholelithiasis is 7 times more frequent in North India, with an overall incidence of about 2–29%. The number and different morphology of gallstones can cause alterations in the gallbladder (GB) mucosa. GB mucosal change depends on the duration of cholelithiasis, size, number, type of stone, and the gender of the patient. The coexistence of gallstones with cholecystitis, hyperplasia, intestinal metaplasia, and carcinoma is well known in the literature. Incidental gallbladder (GB) carcinoma is revealed in 1% of all cholecystectomies done for benign conditions. The pathological stage of the disease decides the prognosis of the disease.
Aims and Objectives: Gallstones are known to produce various histopathological changes in the GB. We aim to correlate gallstone characteristics such as (number and morphological type) with the type of mucosal response in the GB (inflammation, hyperplasia, metaplasia, and carcinoma).
Materials and Methods: A study of gallstones was done in 184 cases of open cholecystectomies based on the histological changes. One hundred and sixty-five (89.95%) were associated with gallstones, and the rest 19 cases (10.05%) were of acalculous cholecystitis. The changes in the mucosa of the calculous GB (165 cases) were studied, and the correlation between the mucosal changes and the number and type of stones was evaluated. Tissue sections for histopathological studies were taken from the fundus, body, neck, and abnormal-looking areas of the GB.
Results: A gender study revealed a higher incidence of inflammatory changes in males, while GB hyperplasia, intestinal metaplasia, and cancer were found only in females.
Conclusion: Correlation of mucosal changes with a number, duration of disease, and morphological type of stones has suggested that there could be an association with the various GB mucosal changes such as inflammation, hyperplasia, metaplasia, and carcinoma of the GB.


The policy of restricting oral intake during labour is well established in many maternity units. However, researchers are now questioning the wisdom of this practice. Midwives who are based within labour suites are becoming increasingly aware of the implications of restricting intake during the intrapartum period.


A multi-layered information recording medium including a plurality of recording layers, the multi-layered information recording medium comprising: a user data area for recording user data; and a plurality of spare areas including at least one replacement region, wherein when the user data area includes at least one defect region, the at least one replacement region may be used in place of the at least one defect region, wherein a first spare area of the plurality of spare areas is positioned so as to be contiguous to a first user data area of a first recording layer, a second spare area of the plurality of spare areas is positioned so as to be contiguous to a second user data area of a second recording layer, and the first spare area and the second spare area are positioned approximately at the same radial position on the multi-layered information recording medium.


With global economic integration, transnational trade plays an important role, and maritime transportation is one of the important means of freight transportation. It is of great significance to build a secure and efficient maritime transportation system (MTS). The introduction of Internet of things technology makes MTS more perfect. The IoT-enabled MTS is composed of marine terminals and on-board sensors, land-based data centers and base stations, as well as satellite networks. Many researchers have carried out significant work to aggregate data in MTS. However, because the terrestrial base stations cannot cover most of the sea area, the isolated maritime terminals, those who drive to the area without base station coverage, need the assistance of satellite networks to complete the contact with the data center. In this paper, we propose an attribute based secure data aggregation scheme for isolated IoT-enabled MTS. In the novel scheme, the constant attributes of a maritime terminal are utilized to generate its certification. In addition, on-board sensors are introduced in the system to help aggregate the status and surrounding environment of the maritime terminal. These monitoring data are encrypted by the sensors and transmitted to the data center for the trustworthiness evaluation of the isolated maritime terminal. Besides, the zero-knowledge proof is utilized to confirm the legitimacy of participating users. What's more, the security analysis and the simulation results show that the novel scheme is secure and efficient for IoT-enabled MTS.


Excellent tracking index as well as flame-resistant properties are achieved with other desirable characteristics of LCPs in a resin composition consisting essentially of: a) a wholly aromatic polyester which is melt processible and which displays anisotropy in the molten state; b) a non-conductive filler material having a diameter of less than about 3 nm, with said non-conductive filler material being present in an amount sufficient to increase the comparative tracking index (CTI) rating of said composition to above 220 volts and render the composition non-burning. Optionally, an extraordinarily small amount of non-volatile fluorescent brightener can be added to the resin composition. In combination with the non-conductive filler, the fluorescent brightener is found to surprisingly and significantly improve the flame-retardant property of the resin.


The specific binding of L‐[3H]‐glutamic acid (GLU) was examined in membrance preparations derived from heads of Drosophila melanogaster. L‐[3H]‐GLU bound to the membrane preparation with biphasic in a reversible and saturable way. The specific binding was inhibited by Cl− and Ca2+ ions. Saturation analysis of the data fit a model of two independent binding sites with dissociation constants (KD) of 29 nM and 249 nM and corresponding binding site densities (Bmax) of 5.7 and 24.6 pmol/mg protein. A series of excitatory amino acid receptor agonists and antagonists were tested as inhibitors of L‐[3H]‐GLU specific binding. Some compounds almost totally abolished the specific binding, whereas others reduced the binding to 45% over the concentration range used. Among the first type of inhibitors, L‐GLU was the most potent, D‐aspartate (D‐ASP) and D‐GLU were 10 times less effective than L‐GLU, whereas quisqualic acid had the lowest potency. Among the second type of inhibitors, glutamate diethyl ester, D‐α‐amino adipate, and N‐methyl‐D‐aspartate showed the highest potency, and DL‐2‐amino‐4‐phosphonobutyrate was the less effective. Kainic acid and γ‐amino butyric acid were not able to modify at any concentration used the specific binding of L‐[3H]‐GLU. These data suggest the presence of putative GLU receptors in the brain of Drosophila.


The concept of next generation Internet was introduced at first, and the characteristic of next generation internet was mainly expounded. Finally, it was showed that studying and developing next generation internet has momentous current significance and far-reaching historical significance.


We present a new algorithm to analyse spatiotemporal signals emerging from nonlinear systems which are close to instability. The algorithm aims at a recognition of spatial modes, both order parameters and enslaved modes, and equations describing the dynamics of the amplitudes by order parameter equations and center manifolds. We demonstrate the method by a simulated example from the field of hydrodynamics (Benard instability) and discuss results of the method applied to spatiotemporal EEG-data of epileptic seizures.


The characteristic of algae groups of city soil, subject to recreational weights is considered. The comparative analyses of systematic and taxonomic structures are carried out. Result of research is definition of reaction of soil algae flora on recreational loading.


Introduction Civil Engineering students at Rose-Hulman Institute of Technology (R-HIT) begin to learn openended, project-based design in a first year civil engineering design course where groups of 3-5 students work for outside clients on a simple civil engineering project. In their Junior year, students participate in a three-course structural engineering sequence (1) where they design a proposed 2 to 3-story campus structure, beginning with design of foundations and preparation of a geotechnical report, and followed by a concrete frame design and steel frame alternative in two subsequent courses. As seniors, civil engineering students work in teams of 3-5 students on a year-long design project for an outside client that produces a quality "real world" engineering work. In other junior and senior year classes, students also complete projects of varying complexity. However, formal design of an engineered system has not been a part of any of the required courses for civil engineers in the sophomore year. Rose-Hulman's academic year uses the quarter system and pushes students to begin engineering course work by the end of their freshman year. By the Winter Quarter of their sophomore year, civil engineering students are enrolled in Mechanics of Materials, having already completed course work in Engineering Statics and Engineering Dynamics. Thus, by the middle of their sophomore year, they have acquired most of the tools necessary for some simple quantitative engineering system design.


Through the methods of document research,statistical figures and comparative analysis,this paper compares and statistically analyzes male and female sports scores,rankings,number of medals,the total score rate and male and female score rate. The paper analyzes the results curve and its trend in the track and field program for secondary school students in Baotou and puts forward many reform proposals.


The narrative found in popular media regarding terrorism invariably tends to portray 'terrorists as crazy extremists who commit indiscriminate acts of violence, without any larger goal beyond revenge or a desire to produce fear in an enemy population.'[1] This perception of terrorism has been bolstered by the so called advent of the age of 'new terrorism', characterised by mass casualty suicide attacks conducted by religious fanatics, primarily of Islamic faith, for whom 'lethality is their aim and not their means.'[2] This fundamentally misinterprets terrorism as nihilistic violence that is an end in itself and contributes to the common misperception that terrorism 'exists beyond the realms of rational activity.'[3] Terrorism is rational, however, when correctly understood as a set of tactics employed by rational actors within a wider strategy of coercive political communication, where violence is used in 'the deliberate creation of a sense of fear... to influence the political behaviour of a given target group.'[4]


We present a study of the phase diagram for a hard sphere interaction site model of benzene using Monte Carlo computer simulation. The investigation considered the fluid phase and three types of solid phases. Two of these are similar to experimentally determined structures of benzene and the third is a structure which allows the system to reach a high packing density at high pressure through a columnar-like arrangement of the molecules. Extensive calculations of the solid and fluid thermodynamic properties were made. The results show that, for the solid phase, the structure which enables the closest packing of molecules is the most stable one. The solid structures similar to those of benzene, while apparently mechanically stable, were found to be thermodynamically metastable for this purely hard core system. The simulation results have been used to test the accuracy of the cell theory for the solid phase and an equation of state for the fluid phase due to Boublik, as well as phase diagram predictions obta...


Abstract : Intersection cuts represent a new type of cutting planes for integer programming. Given an integer program, the basic idea of these cuts is to intersect the boundary of some convex set circumscribing the unit cube that contains a basic feasible, but noninteger, solution x bar to the associated linear program, with the n halflines originating at x bar and defined by the problem constraints that are tight for x bar. The n intersection points then define a valid cut. (Author)


A time reversal transformation transforms a process into its inverse, and is stated mathematically by the transformation of time t→t′=−t. The velocity potential Φ(r,t) and its Fourier transform φ(r,ω) are transformed into Φ′(r,t′)=−φ(r,−t) and φ′(r,ω)=−φ*(r,ω), respectively. It is proved that the time reversal of a source is a receiver and vise versa. The signal received by a receiver at r2 in the field φ(r,r1;ω) produced by a source at r1 is defined by φ(r2,r1;ω)=Fds⋅φ(r,r,ω)∇φ′(r, r2ω), where the surface integral is taken around the receiver. Here, φ is proportional to the power absorbed by the receiver. This theory leads to an important assertion that for a reducible transducer, if the frequency spectrum is f(ω) and the directional factor is D(θ,φ) when it is used as a source, then the frequency response and directional factor when it is used as a receiver must be f*(ω) and D*(θ,φ), respectively. The theory is applied to a cross borehole prospect. The radiation pattern produced by a source borehole a...


This study assesses changes in mobility behaviour in the City of Barcelona due the COVID‐19pandemic and its impact on air pollution and GHG emissions. Urban transport is an important sourceof global greenhouse gas (GHG) emissions. Improving urban mobility patterns is therefore crucial formitigating climate change. This study combines quantitative survey data and official governmentdata with in‐depth interviews with public administration officials of the City. Data illustrates thatBarcelona has experienced an unprecedented reduction in mobility during the lockdown (a 90%drop) and mobility remained at comparatively low levels throughout the year 2020. Most remarkableis the decrease in the use of public transport in 2020 compared to pre‐pandemic levels, whereas roadtraffic has decreased to a lesser extent and cycling surged at times to levels up to 60% higher thanpre‐pandemic levels. These changes in mobility have led to a radical and historic reduction in airpollution, with NO2 and PM10 concentration complying with WHO guidelines in 2020. Reductions inGHG emissions for Barcelona's transport sector are estimated at almost 250.000 t CO2eq in 2020 (7%of the City's overall annual emissions). The study derives policy implications aimed at achieving along‐term shift towards climate‐friendlier, low‐emission transport in Barcelona, namely how torecover lost demand in public transport and seize the opportunity that the crisis brings for reform byfurther reducing road traffic and establishing a 'cycling culture' in Barcelona, as already achieved inother European cities.


this paper propose the necessity of carrying out user information literacy using the library website in knowledge economy age. And it analysis of the status and the reason about the user information literacy education based on the library website. Then it propose the content、methods、and development proposals about the user information literacy education based on the library website.


Purpose
The purpose of this paper is to analyze and optimize the roller burnishing process parameters using the design of experiments and grey relational analysis (GRA).

Design/methodology/approach
In this experimental work, the carbide burnishing tool has been selected for the machining of AISI-1040 high carbon steel to get better product quality and satisfactory machining characteristics. The material surface condition while machining, burnishing tool speed, feed rate, depth of penetration and No. of passes have been selected as process constraints to conduct experimental trials.

Findings
The surface roughness (SR) and surface hardness were considered as output responses. The experimental outcomes optimized by multi-parametric optimization showed considerable improvement in the process. The roller speed and number of passes are the most significant parameters for surface hardness, whereas the surface condition and roller penetration depth have the most significance on SR.

Research limitations/implications
The GRA method shows the 0.03376 improvement in grey relational grade between the experimental values and the predicted values.

Practical implications
The experimental outcomes optimized by multi-parametric optimization showed the considerable improvement in the process and will facilitate steel industries to enhance and improve productivity while burnishing high carbon steel (AISI-1040).

Originality/value
This research represents valid work, and the authors have no conflict of interests.


Abstract Positive periodic solutions of the equation ẍ + x = g(t)xp-1 are considered with continuous and T-periodic g. Some existence results of solutions are obtained by variational method.


Transfer faults (Gibbs, 1984), are often interpreted as accommodating differential extension in sedimentary basins. Frequently the definition of such .features is contentious as they can be difficult to map using seismic data. Aeromagnetic data however can provide excellent mappings, of transfer faults in situations where extensive magnetic markers exist in the area undergoing extension prior to the extension. In such cases the extension will fracture and/or dislocate the magnetic markers and the transfer faults and the relative movements will be indicated by present day geometries of the magnetic sheets which can be deduced from aeromagnetic data. These conditions occur in the Bonaparte Basin of northwestern Australia and in the 0tway and Bass Basins of southe astern Australia.


There is a long history of approaches for predicting the need for hospital beds at specific locations. Past methods have tended to regard as key variables the ser vice area population, hospital use rate per population unit, average length of stay, and occupancy rates. The usual client for a bed-need study is an individual hos pital. There is no constraint on the forecasting meth odology to ensure that if the approach used for one hospital were to be applied to many hospitals, the sum mation of the forecasts for a region would yield re sults that are consistent with macro-regional forecasts of bed need. The methods used in this study are de signed to produce such consistent system-wide forecasts when aggregated from individual-level forecasts. That is, a system of allocations of patients to hospitals in individual places is made with a sufficient accounting of flows of patients from each area to all hospitals that hospital-use rates for individual areas prevail irrespective of the particular hospitals patronized. Such a system-wide simulation model corrects for the major flaw in most existing procedures in which the system-wide effects of adapting


The fact that rainfall data are usually more abundant and more readily regionalized than streamflow data has motivated hydrologists to conceive methods that incorporate the hydrometeorological information into flood frequency analysis. Some of them, particularly those derived from the French GRADEX method, involve assumptions on the relationship between extreme rainfall and flood volumes and on their probability distributions. In particular, for rainfall probability distributions exhibiting exponential-like upper tails, it is possible to derive the shape and scale of the probability distribution of flood volumes by hypothesizing the basic properties of such a relationship. This paper focuses on a parametric mathematical model for the relationship between rare and extreme rainfall and flood volumes under exponentially-tailed distributions. The model was fitted to rare and extreme events as derived from the hydrological simulation of long stochastically-generated synthetic series of rainfall and evaporation for the Indaia river basin, located in south-central Brazil. In addition, the paper provides a sensitivity analysis of the model parameters. Analysis of the results provides grounds to draw conclusions regarding the relative positions of the upper tails of the probability distributions of rainfall and flood volumes


Consensus Edge Computing and Its Applications in Energy Internet WANG Tonghe, HUA Haochen, CAO Junwei (1. Tsinghua University, 100084, Beijing; 2. Hohai University, 210098, Nanjing, Jiangsu; 3. Beijing National Research Center for Information Science and Technology, 100084, Beijing) ABSTRACT: Edge computing and consensus are two important research topics in the field of distributed computing. Edge computing delegates some resources to the edge near terminal devices improve the efficiency and quality of computing, while consensus provides security for distributed systems by achieving the consistency among the states of distributed individuals. Based on a brief review of related literature, this paper summarizes and analyzes the reciprocity between edge computing and consensus: the edge computing architecture provides innovation for the theoretical model of consensus study, and consensus provides desirable security for edge computing systems. In this paper, edge computing and consensus algorithm are combined organically, and the concept of "consensus edge computing" is established. The application of this combination is prospectively analyzed under the background of Energy Internet, and then possible development directions are enumerated.


In order to solve the problem that the mechanical properties of epoxy resin( EP) will deteriorate after adding the common brucite flame retardant,a newflame retardant was prepared through the modification and synergizing of brucite. The surface morphologies of both brucite powders and fracture surfaces of flame retardant EP were observed with scanning electron microscope( SEM). The mechanical properties of flame retardant EP were studied with the bending strength test,and the flame retardancy was investigated with the oxygen index test. The results showthat the properties of flame retardant EP with the brucite content of30% are the best. When the brucite is modified with silane coupling agent I and Z6173,the bending strength and oxygen index of flame retardant EP are 5. 21 M Pa,28. 9% and 4. 82 M Pa,29. 1%,respectively.When the composite flame retardant is prepared with 6 phr zinc borate and the brucite is modified with silane coupling agent I,the bending strength and oxygen index of prepared flame retardant EP are 4. 85 M Pa and29. 3%,respectively.


In this contribution we evaluate pilot-based carrier frequency offset (CFO) estimation and its correction in a filter bank based multicarrier (FBMC) system. We show that by applying certain pilots designed specifically for filter banks, the CFO can be accurately estimated. The performance evaluation is done in a hypothetical WiMAX scenario in which an FBMC system would substitute OFDM maintaining as much physical layer compatibility as possible.


The purpose of the proposed intervention is to revive the use of heritage through accessibility and sustainability strategies. The innovative approach of the proposal is to propose reversible and ecological actions that provide access to the San Fernando Castle in Alicante through mechanical access from a new Interpretation Center in which the bastion is placed in value with the rest of the defensive system from the city. The intervention generates an accessible public space following ecological criteria, without considering the natural and the urban as two spheres confronted but in symbiosis. To complete the access, a panoramic elevator and a mechanical ramp are proposed which, through integration strategies in the environment, facilitate access to the fort. The proposed bioclimatic strategies such as the vegetation cover, the water sheet or the covered square make possible the interaction between the urban and the natural in a delicate ecosystem equilibrium, while respecting the integration with the historical environment.


Whilst we cannot refrain from congratulating I/ieut.-Col. J. W. D. Megaw, v.h.s., c.i.S., on his recent promotion last February from the post of Director of the Calcutta School of Tropical Medicine to that of Inspector-General of Civil Hospitals, Punjab, yet we most sincerely deplore his. loss to the Calcutta School Tropical Medicine, and his relinquishing the post of editor of this journal. The Indian Medical Gazette has had many distinguished editors, but never one who was more suited


Interventions using prebiotic inulin‐type fructans (ITFs) are widely prescribed to modulate the gut microbiota composition and activity to promote health. However, the impacts of ITFs on post‐antibiotic reconstitution of the gut microbiome remain incompletely understood. The aim of the present study was to investigate the effects of ITFs supplementation on intestinal inflammation, the composition of the intestinal microbiota and the colonic transcriptome after antibiotic treatment.


Rutile pigment with preadsorbed monomers of acrylamide (AM) or acrylic acid (AA) has been treated in air corona discharges at various input power levels for times from 30–120 s. Inverse gas chromatographic data showed that the treatments reduced dispersive surface energies and significantly altered the acid/base interaction potential of the surfaces. Inferred is the corona-activated synthesis of oligomeric or polymeric structures anchored to the pigment surface. XPS analyses report modifications in the chemical structure of pigment surfaces, which are consistent with the suggested consequence of corona treatment. When incorporated into LLDPE and PVC host polymers, compounds with the corona-modified rutiles have better mechanical properties than analogues with untreated pigment, notable being improved elastic moduli, yield stresses, and stress/strain relationships at break. AM-modified rutiles were preferable to AA-modified versions in this regard. The addition of treated pigments to immiscible LLDPE/PVC (75/25) blends resulted in similar benefits to mechanical properties, AM pretreatment again being preferred. Stronger acid-base interaction at contacts between corona-modified rutiles and the PVC component is an apparent reason for improved mechanical properties. Speculatively also, AM pretreatments lead to attached chains of sufficient length to entangle with the LLDPE, further strengthening the interphase and relevant bulk properties. © 1998 John Wiley & Sons, Inc. J Appl Polym Sci 70: 1597–1604, 1998


T HE balance of international payments of the United States consists of the payments made, within a stated period of time, between residents of the United States and residents of all foreign countries. In addition to merchandise, and gold and silver exports and imports, the international business of the United States includes the purchase and sale of various kinds of "invisible" services such as shipping, travel accommodations, banking and insurance serv-


This paper analyzes the existence of global attractor of dynamical system in Banach space by flattening property, using measure of noncompactness. The global attractor is a nonempty, compact, and invariant set which attracts every bounded subset of the space which the system defined. The initial stage we prove the existence of global attractor by concept ω-limit compact with measure of noncompactness methods in a metric space complete. Then we indicate that concept ω-limit compact equivalent with the flattening property in Banach space. If the flattening property is hold and there exist an absorbing set on the system, hence the existence of global attractor in that system is proven to be exist.


One kind of novel free porphyrin o-(L-Tyr)C2O-TPP and o-(L-Tyr)C2O-ZnTPP modified with L-Tyr by nucleophilic substitution were designed,synthesized and characterized by means of elementary analysis,UV-vis,1H NMR,CD spectra,IR and fluorescence spectra.


RPBT by measuring Ev2 has been used mostly in construction field of high-speed railway in Korea in order to verify degree of compaction of the trackbed foundation materials. Recently LFWD and LWDT have been used widely in foreign countries including Germany and China because those methods are easy to measure stiffness of the track foundation comparing to RPBT. In this study, RPBT, LFWD and LWDT are adapted to measure stiffness of the track foundation in Honam high-speed rail construction field. The measured values of Ev2, ELFWD and Evd are compared each other to get correlation among them so that a possible way of adapting LWDT is proposed based on the reliability from the correlation analysis.


Wireless body area network (WBAN) has made a significant contributions in health monitoring. However, due to the limited energy supply, sensor nodes must achieve physiological measurements with minimum energy consumption in order to maintain long-term monitoring. In this article, we design a kinetic energy harvestion device to provide energy for sensor nodes and propose a energy level classification routing protocol (ELC) to simultaneously optimize network lifetime, transmission reliability and energy efficiency. The protocol comprehensively considers several WBAN parameters such as residual energy, transmission distance and link reliability of the sensor node as the factors of the multi-objective optimal function, and adjusts the weights of these factors based on the entropy method according to the actual measured data. After extensive simulation comparisons with other existing routing protocols the results show significant improvement in network lifetime, transmission reliability and energy efficiency.


Strategic Noise Maps in Europe are supported mainly by Directive 2002/49/EC and by Good Practice Guide for the preparation of Strategic Noise Maps. These documents address mainly four types of noise sources: Roads, Railways, Airports and Industries and was therefore not included Recreational Activities. This article seeks to justify the need for inclusion of Recreational Activities in Strategic Noise Maps, present some examples, and the main difficulties associated with, and present the main methods that can be used for characterization and modeling of this special type of noise source.


The invention relates to a non-cutting produced from a steel sheet lever-like cam follower (1) for a valve drive of an internal combustion engine for applying at least one gas exchange valve. This lever-like cam follower (1) is characterized in that it is made of a cold-formable, fully hardenable heat-treated steel.


I present the discovery of a new stellar companion to GJ 1292 detected with the NN-EXPLORE Exoplanet and Stellar Speckle Imager at the 3.5 m WIYN Telescope. The companion was detected at an angular separation of 0.″1244, a position angle of 44°, and a delta magnitude of 0.97 at 832 nm. I also estimate a projected separation of 2.09 au, a mass ratio of 0.69, and component spectral types of M2.5 and M3.


Electromagnetic compatibility (EMC) is the scientific/engineering discipline of ensuring that electrical and/or electronic technologies do not emit levels of EM energies that cause excessive EMI. It is also concerned with ensuring that they do not suffer untoward EMI during operation. This article explains why the conventional approach to EMC – which is based solely on testing (usually in an EMC laboratory) – can never be sufficient to demonstrate that safety risks due to EMI are tolerable. It will introduce a recent IEC document on this issue, and the Institution of Engineering and Technology's very practical and detailed guide on how to do EMC for Functional Safety properly.


These two studies examine the usefulness of metaphor in reminiscence groups. The purpose of this research is to determine whether metaphor prompts the reminiscer to share more of his or her life @with a group and enhance the pleasurable experience of reminiscence for both reminiscer and listener. In Experiment 1, subjects in a group setting performed one of three tasks: (a) produced metaphorical sentences, (b) produced nonmetaphorical sentences, or (c) read and answered questions about a story. Subjects orally related an experience from his or her past. The number of propositions produced was measured. Subjects rated how much they enjoyed relating the experience, how comfortable they were, and how easy it was to do so. More propositions were produced in the metaphor condition. In Experiment 2, subjects listened to a tape of an elderly man reminiscing; One tape contained metaphors, one did not. Subjects rated how pleasurable the listening experience was, and their memory for details from the tape was asses...


White-collar offenders' characteristics are thought to mediate the way they experience criminal justice. This is the background for this chapter's exploration of their correctional experiences. It begins with discussion of offenders' special sensitivity to punishment, the extent to which white-collar offenders constitute a broadly similar group of offenders and how they may resist taking on a criminal identity. Explorations of their imprisonment emphasize the shock of the transition to prison for white-collar offenders, who cope by drawing upon previous experiences or making themselves useful within prison. This aside, they appear to face no special difficulty adjusting to prison. Less is known about their experience of community corrections, although a perception by both offenders and supervisors that these may offer little of use may mar their effectiveness. The chapter ends by giving consideration to the experiences of white-collar offenders in the wake of punishment, including processes of shaming as they relate to attempts to punish white-collar offenders and more general concerns around their desistance from crime.


The establishment of students' development theory stems from the practical needs of students' affairs management in university.Foreign students' development theory matures gradually.The work for students in our country should center around the goal of promoting their comprehensive development,form cooperative cohesion,run school by law,standardize system and perfect service system to strengthen the establishment of specialization and professionalization of ranks.


Transition-when the cervix dilates from about 7 cm. to 10 cm.-is generally considered the most difficult phase of labor and it is at this time that the couple who have learned a psychoprophylactic technique, such as the Lamaze method, face their most stringent test. Control can be precarious. When a couple know what to expect in transition, however, they are more likely to be able to remain in control of the labor. Because drowsiness is one of the


SUMMARY: The modified Rogosa media (acetate broth and acetate agar) developed by Mabbitt & Zielinska (1956) have been compared with tomato juice media for the growth of representative Lactobacillus species.

Most of the species tested grew markedly better in acetate broth than in tomato dextrose broth, but some cultures did not grow well in the acetate broth although they grew normally in tomato dextrose broth. The acetate agar was satisfactory for counting those lactobacilli cultured at 30° but was inferior to tomato dextrose agar for counting those grown at 37°.


This is a tutorial describing how the time-dependent diffusion coefficient D(t) of mobile molecules confined in pores or cells carries information about the confining geometry. At early times, D(t) = D0[1 − (4/9)(S/Vp)] gives, irrespective of details, the pore surface to volume ratio (S/Vp), which is a measure of microscopic length. Here D0 is the bulk unrestricted diffusion coefficient. At long times, D(t) reaches a limiting value D0/α at a rate that depends on macroscopic length scales characteristic of the medium. The geometrical parameter "tortuosity" α plays an important role in various transport processes in porous media, such as the electrical conductivity. Extensions of these concepts to permeable pore walls, fluid identification by combining diffusion with relaxation, restricted diffusion in inhomogeneous magnetic fields leading to edge enhancement, and fractal surfaces are briefly described. © 2004 Wiley Periodicals, Inc. Concepts Magn Reson Part A 23A: 1–21, 2004


The purpose of this paper is to demonstrate how a legal power can be executed not only through an action but also by omission. Taking as starting point the conception about power con- ferring rules of ATIENZA and RUIZ MANERO and a conception of omission taken from VON WRIGHT, the author argues, using some samples, how is possible to execute a facultative power conferring rule by omission. Finally, the paper analyses those cases in which the legal system, before cer- tain passive conducts of the agent concerning the execution of a power of obligatory exercise, establishes a purely constitutive norm that attributes a legal effect to that abstention, without being possible to consider that passive conduct an exercise of a power-conferring rule by omission.


Qulong porphyry copper(molybdenum) deposit, which is located in the arc-basin transform place between the magma arc of eastern Gangdise and Riduo basin, controlled by basin-controlled, rock-controlled structure in basin edge, and formed in instantaneous transition environment of transform from convergent to extension, is the most potential superlarge deposit in ore-finding and its finding is the important breakthrough in the exploration process of porphyry deposit in eastern belt of Gangdise Mountain. The ore fluid of Qulong porphyry copper(molybdenum) deposit is composed of saturation and supersaturation brine-steam boiling fluids; its distribution characteristics of wall rock alteration include centering by porphyry, surfacing, and annular zone; it has undergone mineralization of 3 periods including 5 phases. It is found that the copper mineralization correlates with anhydrition and sericitization. This paper also probes into some key science issues which call for further studies and attention.


An improved version of single-molecule force spectroscopy (SMFS) has enabled researchers to study the unfolding of a membrane protein with much higher time resolution and force precision than ever before, revealing a multitude of new details. Proteins must adopt specific three-dimensional shapes to work properly. If they don't, they can malfunction or cause protein-misfolding conditions such as Alzheimer's disease. Scientists would therefore like to better understand how proteins fold and unfold, including all the intermediate states they adopt along the way. One type of SMFS technique probes protein-folding intermediates by using an atomic force microscopy (AFM) cantilever to pull on a single protein molecule, unraveling it a little at a time. Most unfolding steps are reversible, so studying unfolding reveals a protein's folding behavior as well. In the past, SMFS studies found two intermediate states in the unfolding of two helices in the membrane protein bacteriorhodopsin. But molecular dynamics simula...


In this article we describe a computer‐controlled active feedback dielectrophoretic (DEP) levitator and its measurement capabilities for characterizing single particles and particle chains (20–500 μm in length). Edge detection using a linear array of photodiodes is employed and an adaptive controller updates the voltage required for stable levitation at a rate of 4.7 kHz. Rms voltage fluctuations are typically less than 0.2% of the levitation voltage. The most precise data to date for the effective dipole moment of conducting particle chains up to four in length are presented along with experimental measurements of the effective dipole moment of two particle chains of unequal size as tests of accuracy and precision of the apparatus.


Objective: To ascertain whether reducing bilirubin level by phototherapy can reverse the changs in the BAER. Methods: Nonhemolytic hyperbilirubinemia infants (without infections, trauma or cephalhematoma) as experimental group, healthy infants with comparable age and bilirubin levels140μmol/L as control group, BAER test was performed on infants received phototherapy at the times just before exposure, after 24 hours of exposure, at the termination of exposure and 24 hours after exposure. And parallel tests were carried out on control infants. Results: BAER in experimental group showed significantly prolonged latency V, interpeak Ⅲ-Ⅴ and Ⅰ-Ⅴ(P0 01,P0 05),and revealed significant difference of latency V values, interpeak lateucy Ⅰ-Ⅴ and interpeak latency Ⅲ-Ⅴ between the preexposure and postexposure. As the bilirubin levels declined in response to phototherapy, concomitant improvement occurred in the BAER. The correlation between bilirubin levels and BAER values during phototherapy was highly significant. Conclusions:Hyperbilirubinemia can result in abnormalities in BAER.Phototherapy is effective not only in reducing serum bilirubin values but in reversing the hazardous effects of bilirubin on BAER as well.


The conceptual approaches to definition of the purposes, principles and directions of the digital transformation of marketing activity of enterprises offering services according to technologies and methods of Marketing 4.0 have been proved on the basis of modern theories of service marketing. The inclusiveness and customer-focused of digital marketing services have been revealed. The omnichannel of marketing communications on the basis of integration and availability of online and offline channels of service enterprises and clients interaction, digitalization of client managerial experience has been substantiated.
The Object of Research: digital marketing of services in the context of the Marketing 4.0 concept.
Investigated Problem: the essence and directions of digital transformations of marketing activities in the field of services.
Main Scientific results: the inclusiveness and customer-focused of digital marketing communications based on cross-channel interaction and digital managerial models of customer experience have been revealed on the basis of the analysis of theoretical approaches to the characteristics of service marketing and determining the directions of its development in the digitalization of the economy and in accordance with the Marketing 4.0 concept.
Field of Practical Usage of Research Results: practical activity of service enterprises on application of digital marketing mix transformations and marketing communications channels.
Innovative Technological Product: the main principles and directions of marketing services digital transformation, that is inclusiveness and customer-focused of marketing communications, omnichannel as integration and availability of online and offline interaction channels as well as digitalization of customer experience management have been substantiated.
Field of Application of Innovative Technological Product: theoretical researches and practice of digitalization of marketing communications of the service enterprises.


The author maintains that the absence of archaeological evidence is not enough to conclude about the crisis or disappearance of Byzantine settlements in mid-7 th – mid-9 th centuries. On certain occasions, these archaeological gaps are filled with the help of the time when important buildings were functioning. In works of M.Ya. Syuzyumov, it was stated that Byzantine provincial towns did undergo a crisis, but did not utterly disappear as a result thereof. The researcher's conclusions are proved by the finds from the closed archaeological sites of Chersonesus, made by Ural University since the beginning of expeditions in 1958 started by E.G. Surov.


introduces assumptions on accumulation, ice-sheet collapse, spatial correlation, mass-balance baseline and growth models, and uses prior distributions on modelling coefficients. Monte Carlo simulations then produce probabilistic predictions in a base case — where input parameters are set to their most probable value — with canonical variations exploring sensitivity to assumptions. Writing in


In view of the backward situation of Northeast old industrial base's economic development,this paper analyzes the chief causes and points out the feasibility of revitalizing the old Northeast industrial base.The paper puts forward the following countermeasures:deepening state-owned enterprises' reform,adjusting industrial structure and economic structure,strengthening regional economic integration,cultivating industry colony competitive advantages,revitalizing Northeast old industrial base to become China's fourth economic growth pole.


As the title implies, this thesis, following Bezanson and others, approaches Moby-Dick by way of the controlling consciousness of its narrator, Ishmael. And further, the thesis explores the implications of treating Ishmael as the 'creatort of the novel, both for the material he has added subsequent to the presumed events he is dealing with, and for the manipulation and magnification of those events which occurs in the retelling or re-creation of the story of Ahab and the White Whale. The thesis makes the assumption that Ishmael's survival is fortuitous, being the last and most catastrophic of the accidents he encounters. His narrative is, therefore, retrospective--a point which is emphasized for its importance to an understanding that Ishmael's narrative is produced in the light of his knowledge of the ultimate catastrophe. Ishmael, because of his fortuitous survival, conceives very tmetaphysicallyt of his situation which, in the years following his rescue by the Rachel, leads him to ponder the meaning of the events in which he was involved and to consider the fundamental problems of human existence which were presented to him so forcibly during his voyage on the


Our second concern is that depression was not measured. Although the exact mechanism has not been fully elucidated, PMDD is attributable to disturbed serotonergic neurotransmission [8], which is a key modulator in depression. Selective serotonin reuptake inhibitors are commonly used for PMDD [9], although detailed descriptions for the type of antidepressants were not presented in the article by Weise et al. [1]. On the other hand, the support-seeking behavior had a positive association with interference in everyday life and symptom intensity in that article. As shown in the study [10] cited by the authors, receiving social support is closely related to depression, particularly in women. We agree with the authors' suggestion that variations in the forms of support and personal variations might have a role in the results; however, it would have been better if depression had been put into the statistical model.


This article examines discourse about Internet addiction and video—game—related suicide in the People's Republic of China. Through an analysis of media reportage, interview transcripts, and chat rooms, a preliminary account of the origins of contemporary Chinese concerns with Internet addiction is provided. This approach differs from biomedical models, which see Internet suicide as a form of mental illness, similar to drug or gambling addiction. This approach draws on anthropological and sociological models of the cultural construction of social problems and argues that concerns with Internet addiction are part of a more general moral crisis faced by Chinese, in response to rapid consumerism, the medicalization of mental illness, and new forms of public and publicity.


Through analyzing the structure and function of airborne Infrared Search and Track System(IRST),a functional simulation model of the Airborne IRST was established based on hiberarchy.In this model,a state optimization method,which can be used in condition of information source interconnection,was presented and the IRST states operation process was researched.The scan process of the IRST was analyzed with Grid Method.The Target Detection process for the IRST system was analyzed though studying the minimum detectable radiant intensity.Experimental result shows the models' rationality and validity.


THE METHOD of payment to private phy¬ sicians supplying home and office care to welfare clients under the Baltimore City Medi¬ cal Care Program was changed January 1,1963, from a capitation system to payment of a fee for each service. For 2 years before the change and for a complete year since the change, monthly statistics have been kept on physician utilization rates and hospital-clinic utilization rates. Since the total care of each outpatient utilizes both the physician and the hospital clinic, the figures for both are somewhat inter¬ dependent, and any change in one may be re¬ flected in a change in the other. Experience for a complete year under the new system of payment to physicians can now be compared with the experience of previous years under the old capitation system of payment. The Baltimore City Medical Care Program, initiated in May 1947, became well established in 1948. The program began with two medical care clinics of the University and Johns Hop¬ kins Hospitals, and the directors of these clinics "secured the services of practicing physicians in the neighborhood to render the necessary home and office care" (1). The total eligible population in 1948 was recorded as 14,000 pub¬ lic assistance clients (1). Today the program encompasses services (physician, clinic, drug, dental^ and eyeglass) to more than 60,000 clients ranging in age from birth to 95 years. Seven


Introduction In January 2013 was received in our lab service a bone marrow sample for cytogenetic analysis. The 61 years old female patient presents an elevated white blood cell count (118,000 x10³/mm³) and clinical diagnosis as Chronic Myeloid Leukemia (CML). According the medical information the treatment began with hydroxyurea 3g daily and allopurinol 300mg daily. Methods We proceeded with cytogenetic examination of the patient's bone marrow aspirate by conventional G-banding analysis performed on unstimulated short-term cultures (24 hrs). FISH for BCR/ABL translocation was tested using a dual fusion dual color probe. Because of the sample stability we were unable to performed RT-PCR test. Results Chromosome analysis showed the translocation (9;22)(p24;q11.2) as a sole abnormality in 100% (20/20) of analyzed metaphases. Chronic myeloid leukemia presents as a specific chromosomal abnormality the Philadelphia chromosome, t(9;22)(q34;q11) which is different from the results obtained where the region of translocation of chromosome 9 was p24 instead of the classic q34. This result suggests it is BCR/JACK2 translocation. The FISH analysis showed the presence of a complex Ph chromosome: ABL con BCRx1 (one fusion) and BCRx2;ABLx2. Conclusion The patient took imatinib without answer. She is still in clinical monitoring with persistent hyperleucocytosis and the treatment is following with hydroxyurea 500mg daily and Interferon 5000 UI three times a week. Further molecular and cytogenetic tests will be performed in a second sample to contribute with evaluation of disease progression and monitoring treatment response. Disclosures: No relevant conflicts of interest to declare.


Introduction
A balanced diet will ensure the body gets the nutrients needed and help it to build a well immune system that prevents diseases and infections. On the contrary, an unbalanced diet can cause the body susceptible to many diseases such as high blood pressure, diabetes and allergies. Besides, someone will easily become obese if the food intake is not balanced, for example excess carbohydrate intake at every meal. Therefore, this project presents a development of a smart food container for balance diet intake that helps to calculate the total calories for each nutrient contained in the meal.
Methods
The smart food container consists of a food container with three compartments, three load cells, an Arduino microcontroller, a liquid crystal display (LCD) and a keypad. Each compartment is for different food with different nutrients content namely carbohydrate, protein and vegetables/fruits. A load cell is placed under each compartment to measure the weight of the food in gram. The weight measured is sent to the microcontroller to calculate the total calories. Each nutrient is given a specific coefficient to be multiplied with the weight to calculate the calories. The total calories will be displayed on the LCD together with the recommended calorie intake. The recommended calorie intake is based on the gender, age and the type of meal. The user can reduce or add the food to get the best total calories needed for each of meal time.
Results, and Discussion.
The total calories and the recommended calorie intake for each nutrient are displayed on the LCD of the smart food container. The total calories calculated can be used as an estimation of calorie intake and is not the real values of calorie intake. This is because when the food is cooked with different recipes, it will have different calories.


where M is nominal money, Y is income, and P and Pe are the price level and the expected rate of inflation respectively. B L consider two alternative representations of the unobservable expected rate of inflation. Their treatment of rational expectations has been discussed by Himarios (1983). This note argues that their treatment of adaptive expectations is in error. The problem can be illustrated using B L's equations (2), (4), and (7):


A study was undertaken to assess the nutrient status of turmeric (Curcuma longa L.) growing soils in relation to Root-knot Nematode of Nizamabad district, Telangana. Twenty eight representative villages were chosen and total twenty eight surface soil samples (0-15 cm) were collected and analysed for available N, P, K and micronutrient status. Results revealed that available nitrogen content ranged from 198 to 285 kg ha, available phosphorus content ranged from 14.0 to 34.0 kg ha and available potassium content ranged from and 232 to 393 kg ha. Soils are deficient to sufficient in Zn and sufficient in available Cu, Mn and Fe. The available DTPA Zn status varied from 0.07 to 6.18 mg kg, Cu status varied from 0.60 to 11.52 mg kg, Mn status of these soils varied from 5.75 to 24.40 mg kg and Fe content varied from 3.93 to 20.60 mg kg.


Abstract With an incidence of 350.000 new cases per year, cancer of the oral cavity ranks among the 10 most common solid organ cancers. Most of these cancers are squamous cell carcinomas. Five‐year survival is about 50%. It has been shown that clear resection margins (>5 mm healthy tissue surrounding the resected tumor) have a significant positive effect on locoregional control and survival. It is not uncommon that the resection margins of oral tumors are inadequate. However, when providing the surgeon with intraoperative feedback on the resection margin status, it is expected that obtaining adequate resection margins is improved. In this respect, it has been shown that specimen‐driven intraoperative assessment of resection margins is superior to defect‐driven intraoperative assessment of resection margins. In this concise report, it is described how a specimen‐driven approach can increase the rate of adequate resections of oral cavity squamous cell carcinoma as well as that it is discussed how intraoperative assessment can be further improved with regard to the surgical treatment of oral cavity squamous cell carcinoma.