This article contains examples of offensive and abusive language as a necessary part of illustrating its research findings. In this article, we address a setting where a conversation agent, also known as a chatbot, cannot be modified and its training data cannot be accessed, and yet a neutral party wants to assess and communicate its trustworthiness to a user in a way that is tailored to the user's priorities over the various trust issues (such as bias, abusive language, information leakage, or inappropriate communication complexity). Such a rating can help users choose among alternative chatbots, developers test their systems, business leaders price their offerings, and regulators set policies. We describe a chatbot rating methodology that relies on separate rating modules for each trust issue, and on users' priority orderings among the relevant trust issues, to generate an aggregate personalized rating for the trustworthiness of a chatbot. The method is independent of the specific trust issues and is parametric to the aggregation procedure, thereby allowing for seamless generalization. We illustrate its general use, integrate it with a live chatbot, and evaluate it on four dialog datasets and representative user profiles, validated with a user survey.


The essays in this collection focus on the need for a radical rethink of current economic policy in Northern Ireland. They cover regional economic development, North/South co-operation, labour market discrimination, and policies for both small firms and multinationals. The authors argue, however, that to create such a framework, and so the conditions for modern regional development, Northern Ireland needs new structures of governance, based on a further disconnection from the mainland.


This study aims to discuss Toni Morrison's postcolonial-ecological perspectives on the Carib's colonial history and nature in Tar Baby. Morrison opens the novel with a Caribbean island as its setting which has been governed and exploited by Western colonists and capitalists. In this island, Valerian Street is an imperialistic-capitalistic exploiter of the Caribbean nature and natives because his candy factory uses sugar and cocoa, products of the Caribbean and of the slave system, as Western colonists and capitalists usually did. He is also a symbol of patriarchy, unsympathetic to the feelings of his wife, son, and servants. However, no family member resists the colonial, patriarchal and anti-ecological imperialist-capitalist. Therefore, Morrison first criticizes the wife's and the two slaves' paralyzed identities more sharply than their masters' imperialism and capitalism. And then she shows that her ideal end is a mutually coordinated fulfillment of decolonialization and ecological values, through her hero's retreating to the eco-black descendants of slaves who were marooned on the island.


Strategic health authority chief nurses are looking at ways of implementing recommendations from the prime minister's commission on the future of nursing and midwifery.


The aims of the present study to investigates the opportunities and barriers that visually impaired students face in higher education at Aligarh Muslim University (A.M.U.). For this study, 20 students, including 15 (75%) males and 5 (25%) females, were interviewed based on the availability of visually impaired students. The result of this study reveals that the visually impaired students experienced three major types of barriers in the university, i.e., barriers in infrastructural accessibilities, barriers in accessing study materials, and in classroom learning.

Received: 17 October 2022 / Accepted: 30 December 2022 / Published: 5 January 2023


A theory for obtaining the conductivity of a uniform plasma as a function of frequency and temperature is presented and compared with a number of recent treatments.


This chapter explores the role of planning's publics within the emergent technocratic landscapes of planning. It does so by drawing on ongoing research into the localism agenda in England and in particular on neighbourhood planning. Neighbourhood planning was introduced in 2011 as a 'community right' to draw up a statutory land-use plan. The chapter explores the extent to which technical and 'expert' knowledge and the power of public and private planners is being challenged or displaced by the knowledge, emotions, and actions of citizen planners. As such, the chapter shows that technocratisation is a more varied and complex process than previously thought and that these seeming spaces of de-regulation are not immune to forms of re-regulation which seek to re-create local knowledge to align with technocratic language and purposes.


This paper describes the evaluation of a communication system called 'Mogic' that aims at stimulating social interaction. The system was designed for empty nesters and their children. A context mapping study revealed that there is a need to share emotions and feelings with each other. An overview of the related work on affective systems and the theoretical models behind them is provided. Several experiments were conducted to evaluate whether there is a consistency in colours and movements that people naturally choose for expressing different emotions. The experiment shows there are variations between participants, but that some elements are consistent. The results of the empirical study with the system suggest that participants find it more difficult to express emotions than to perceive emotions. The paper concludes with suggestions for possible improvements to the system and suggestions for further user studies.


Dear Editor-in-ChiefThe term malpractice is used nowadays mostly as if it is synonymous with mistakes made in medical procedures, but in Latin it means bad, wrong implementation of any kind. In Law dictionary it is applied to situations where a member of a profession causes damage to a person at the receiving end of a professional service because of the neglect of standards demanded by that profession from its practitioners of average competence and standing, as a result of their not practising their profession with due care and competence (1). The term medical malpractice is used for cases of wrong procedures by members of the medical profession (2). Some data are available indicating that medical errors have increased in recent years. However, different factors play a role in this increase. For example, with advances in technology physicians are at times led to undertake medical procedures which they have not previously attempted, and such procedures can carry high risk factors. There is also increasing pressure on physicians from the rising cost of medical services. On the other hand there is also some confusion between on the one hand the right to obtain attainable and available medical provision and on the other the right to be healthy which cannot be guaranteed. In addition to these the media do not always show the medical profession in a positive light (3). For any medical procedure to comply with legal requirements it must be undertaken by persons authorized to do so by law, it should be carried out on the basis of medical science data and in accordance with the objectives prescribed in law, and it should be performed with the full knowledge and consent of the patient (4). Financial solutions to the provision of health care differ from country to country. There are different systems in place for compensation arising from the provision of medical services in different countries. In the USA, Germany and Italy there are systems that are based on culpability whereas in Britain, Sweden and New Zealand that is not the case. France and Australia have developed systems which are a combination of the two. Research on this area has revealed that half of the money within the insurance system is used for legal expenses instead of patients, that it take on average 3 to 5 years for a legal case to be finalised and that of 14 patients who have suffered major damage only 1 has been fully recompensated (5-7). With allegations of medical malpractice on the increase daily, it is very difficult for physicians to put a distance between themselves and thoughts of malpractice. This research, conducted with the participation of 222 physicians working at Gu- lhane Military Medical Academy, sought to evaluate views of military physicians on malpractice, compulsory professional liability insurance and compensation issues. The survey is in five parts: the first consists of four questions covering sociodemographics, the second has seven questions under the heading "Views on medical malpractice"; the third part consists of two questions regarding solutions provided and/or suggested, the fourth part has four questions on professional liability insurance and the last part has ten questions on views on compensation. There are 27 questions in all. Data from the questionnaire have been analysed using the SPSS 15.0 programme.The findings of our study also indicate that the main reason for medical malpractice is insufficient numbers of medical personnel, and the main reason for the increase in the number of complaints and legal cases is heightened awareness of patients' seeking to obtain their rights. The reason why medical malpractice is topical is the attitude of the media. Violence against physicians was associated to malpraktice . …


In this paper an approach will be presented which uses data from Business Process Management Systems (BPMS) to determine the communication context of individuals in corporations. It is intended to contribute to a closer alignment of the disciplines Business Process Management (BPM) and communication technology. Therefore, we provide a conceptual integration model for BPM and communication technology by deducing the potentials of BPMS to serve as data source for the identification of a business-related communication context. This is complemented by the system architecture and the prototype of a communication-integrated BPMS which has been implemented during a recently finished consortium research project.


The process of elections is an ever-evolving democratic process in India. One debate revolves around the introduction of the right to negative voting. In this paper, I look at the recent Supreme Court of India judgment that affirms this right through the option of "None of the Above" on the voting machine. Through this judgment and the rules in this regard, I analyse the arguments in favour of and against this right, how under the cloak of a fundamental right this rule has evolved and what this means for India's democracy today.


Because the N‐ and C‐terminal amino acids of the catalytic (c) polypeptide chains of Escherichia coli aspartate transcarbamoylase (ATCase) are in close proximity to each other, it has been possible to form in vivo five different active ATCase variants in which the terminal regions of the wild‐type c chains are linked in a continuous polypeptide chain and new termini are introduced elsewhere in either of the two structural domains of the c chain. These circularly permuted (cp) chains were produced by constructing tandem pyrB genes, which encode the c chain of ATCase, followed by application of PCR. Chains expressed in this way assemble efficiently in vivo to form active, stable ATCase variants. Three such variants have been purified and shown to have the kinetic and physical properties characteristic of wild‐type ATCase composed of two catalytic (C) trimers and three regulatory (R) dimers. The values of Vmax for cpATCase122, cpATCase222, and cpATCase281 ranged from 16‐21 μmol carbamoylaspartate per μg per h, compared with 15 for wild‐type ATCase, and the values for K0.5 for the variants were 4‐17 mM aspartate, whereas wild‐type ATCase exhibited a value of 6 mM. Hill coefficients for the three variants varied from 1.8 to 2.1, compared with 1.4 for the wild‐type enzyme. As observed with wild‐type ATCase, ATP activated the variants containing the circularly permuted chains, as shown by the lowering of K0.5 for aspartate and a decrease in the Hill coefficient (nH). In contrast, CTP caused both an increase in K0.5 and nH for the variants, just as observed with wild‐type ATCase. Thus, the enzyme containing the permuted chains with widely diverse N‐ and C‐termini exhibited the homotropic and heterotopic effects characteristic of wild‐type ATCase. The decrease in the sedimentation coefficient of the variants caused by the binding of the bisubstrate ligand N‐(phosphonacetyl)‐L‐aspartate (PALA) was also virtually identical to that obtained with wild‐type ATCase, thereby indicating that these altered ATCase molecules undergo the analogous ligand‐promoted allosteric transition from the taut (T) state to the relaxed (R) conformation. These ATCase molecules with new N‐ and C‐termini widely dispersed throughout the c chains are valuable models for studying in vivo and in vitro folding of polypeptide chains.


Since its recognition as a social problem in the 1980s, homelessness has not abated. A signature feature of contemporary homelessness is a life in public. Sociological research on the relationship between "sheltered" and "street" homeless populations emphasize their overlapping nature. Yet many homeless people who create "makeshift" housing solutions actively resist shelterization and contest the view that they are in fact homeless. Examining the resources and risks associated with makeshift housing suggests that it provides increased social and structural opportunities yet comes with risks that threaten community longevity. Vehicles are a type of makeshift housing that offer the potential for privacy, ownership, and mobility, unique resources among makeshifts. Using the case of otherwise homeless people living in their vehicles in Santa Barbara, California, this article examines how they acquire and maintain their vehicles and explores the conditions that provide for or threaten their status as a semipermanent housing solution.


ogy, progress with pediatric studies and labeling has been delayed. Following publication of data which might support a labeling change, it should be acknowledged that only the sponsor can request labeling changes, or special consideration for labeling changes can be considered at the initiative of the FDA. We are delighted to hear of the success of the correspondents in their preparation of the current trials by having contacted the FDA and used an Investigational New Drug application to support the current studies. This route should be considered for any new pharmaceutical that investigators believe will have significant impact in pediatric care but does not have the support of the sponsor. We are pleased to have had initial communications with the manufacturer of dexmedetomidine, Hospira, Inc., in initiating sponsor-funded pediatric trials. A Gordian Knot may not easily be untied, but one historical anecdote states that Alexander the Great "cut through it with a sword." As Dr. Su and colleagues suggest, maybe the solution is not so complex if interested parties decide it is a priority. We appreciate the opportunity to focus attention on the easily disregarded needs of children's health in anesthesia and other fields of medicine.


The invention discloses a method for synchronizing nodes. This method for synchronizing at least two nodes in communication with at least one terminal in a wireless network, each node transmitting synchronization sub-frames, each synchronization sub-frame being aligned to an actual synchronization time is characterized in that it comprises a preliminary step of defining, for each node a virtual synchronization time, and in that the method further comprises the steps, carried for each node, of: determining (46) the virtual synchronization time of the at least another node; computing (50) an update of the virtual synchronization time of said node using the virtual synchronization time of the at least another node; and changing the actual synchronization time of said node according to its updated virtual synchronization time.


Background—Multiple clinical trials have shown that neoadjuvant systemic therapy has a benefit in women who are borderline lumpectomy candidates and in those with locally-advanced breast cancers by reducing the mastectomy rate and making inoperable tumors operable. The study aim was to examine the patterns of neoadjuvant chemotherapy and endocrine therapy use among younger women in the US treated at different types of cancer centers. Study Design—Data from the National Cancer Data Base for 118,086 women younger than 65 with clinical stage IIA (T2N0 only) to IIIC breast cancer. Following the National Comprehensive Please send communications and reprint requests to: Ronald C. Chen, MD, MPH, Department of Radiation Oncology, University of North Carolina Hospitals, CB #7512, Chapel Hill, NC 27599-7512, Tel: 984-974-0400 Fax: 984-974-8607, email@example.com. Financial Disclosures: We have no disclosures to report and no conflicts of interest. Disclaimer: This study used the National Cancer Data Base. The interpretation and reporting of these data are the sole responsibility of the authors. Author Contributions: Dr. Chen had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: All authors Analysis and interpretation of data: All authors Drafting of the manuscript: Mohiuddin, Chen Critical revision of the manuscript for important intellectual content: All authors Statistical analysis: Deal Study supervision: Chen HHS Public Access Author manuscript J Am Coll Surg. Author manuscript; available in PMC 2018 July 25. Published in final edited form as: J Am Coll Surg. 2016 November ; 223(5): 717–728.e4. doi:10.1016/j.jamcollsurg.2016.08.541. A uhor M anscript


The poverty happens widely in China rural area, and the outflow of rural fund deteriorates the anti-poverty problem. Civilian credit rises from the rural economy, and takes place in high frequency, on a large scale, with a huge number of users and a good repaying record, which has become the main financing source for rural economical bodies and shown its active role in the growth of rural economy and relief of rural poverty. Based on the static grey-relevancy and forward-moving dynamic grey-relevancy matrix, the results indicate that civilian credit can relieve rural poverty effectively. At the same time, in order to promote the anti-poverty effectiveness, not only the civilian finance market but also the normal finance market should be improved, and the rural economical structure should be optimized.


Sprays were applied to single-tree plots in a randomized block design consisting of 3 replicates of 'York Imperial' and 3 replicates of 'Golden Delicious'. Treatments were applied with a Friend Airmaster 393 sprayer at 25 gpa/alternate side spray driven at 2 mph. Rates of treatments are listed as amounts/acre/alternate side. Spray dates for treatments were: May 19 nd 26; Jun 4, 12, 22 and 30; Jul 8, 16, 24 and 31; Aug 10, 19 and 28; Sep 4. Fungicides applied during the season were: Cyprex, Polyram, sulfur, captan, zineb and calcium chloride. Average temperatures were: May 59.9°F, Jun 9.9°F, Jul 73.2°F, Aug 70.0°F and Sep 62.6°F. Rainfall in inches averaged: May 3.17, Jun 4.11, Jul 2.79, Aug 4.08 and Sep 3.02. Effectiveness on the apple aphid was evaluated by counting the number of aphid infested leaves/10 top terminals, and the number of aphids/most infested leaf/infested terminal. The effect of the sprays on the white apple leafhopper was evaluated by counting the number of nymphs/25 leaves/tree.


Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disease that affects the body's ability to turn food into energy. Normally, after eating, sugar in the form of glucose from the food enters the bloodstream. The hormone Insulin, released from the pancreas in response to the rising levels of glucose in the bloodstream, is responsible for transporting the glucose into the body's cells, to be used as fuel. In Type 2 Diabetes, the body does not respond well to insulin. As a result, the cells cannot absorb the glucose properly and it remains and builds up in the bloodstream and damages the inner lining of the small blood vessels. Uncontrolled diabetes may lead to blindness, limb amputation, kidney failure, and nerve damage. Diabetes is also a prominent factor in accelerating the hardening and narrowing of the arteries (atherosclerosis), leading to stroke, heart disease, and other small blood vessel disorders. The objective of this study was to investigate the "Prevalence of type 2 diabetes patience of J.P.N. Apex Trauma Center (JPNATC) AIIMS New Delhi". This study has been carried out in different parameters age groups, educational status, and socio-economic status. Therefore a cross-sectional survey was conducted among age group (18-72 years) in various wards of J.P.N Apex Trauma center viz. TC-1, TC-4, TC-5, TC-6 and TC-7. The survey revealed 90 males and 26 females. The study showed the prevalence was highest TC-7 and lowest in TC-1. This study also showed that the prevalence of type 2 diabetes mellitus more in urban area compare to rural area(J.P.N.A AIIMS).


Recently, a parametric average-value model (PAVM) has been presented for diode rectifiers with internal faults, which considers their asymmetrical operation by including the ac-side harmonics in both positive and negative sequences. In this letter, the PAVM methodology is extended and generalized for thyristor-controlled rectifiers with faults. The presented PAVM considers the firing angle of thyristors in its formulation. Using extensive computer studies, the proposed PAVM is verified to reconstruct the detailed model results even under dynamics of thyristor firing angle control under faulty conditions, while providing faster and more efficient simulations compared with the detailed model.


Abstract The opinion might easily be formed from glancing at the title of this paper that I intended to convey information relating to the pure economic side of the experience I have gathered during my last few years of practicing the science of poultry husbandry along settlement lines. If this opinion is formed I must here state that such is not my intention. This side of the Soldier Settlement Board in Canada or of the poultry work done under the same in my territory is too large a factor to discourse on in the short time I have at my disposal but information relating to this work could probably be obtained from Ottawa. By many the opinion might be formed that such a subject is hardly worth consideration. I might have chosen other titles but I considered that this one gave more scope for a short paper. Working along lines where . . .


PURPOSE: An indoor unit of an air conditioner is provided to have a filter efficiently removing pollutant introduced together with air through an inlet, and easily attached to and separated from the inlet. CONSTITUTION: An inlet(12) has a suction grill(31) hingedly coupled to one side of the inlet, and rotated to open and close the inlet; and a filter(40) detachably installed to an inside of the suction grill to cover the inlet. The suction grill is rotated and opened to allow the filter to be attached and separated. The inlets are formed on both sides of a cabinet(10), respectively. The suction grills and the filters are paired to be installed on the inlets formed on both of the sides of the cabinet, respectively. A tubular suction channel(30) is formed on the inlet. The filter is formed correspondingly with the suction channel to separate pollutant from air passing the suction channel. Guide grooves are formed on an upper side and a lower side of the suction channel to support an upper end and a lower end of the filter so that the filter is installed on the suction channel. A plurality of supporting bars(32) have both ends installed on both sides of the suction channel, respectively, to support an inside of the filter. Fixing hook is protrusively formed on the suction channel to be fixed to an end of the filter to support the end of the filter.


There are, no doubt, a variety of reasons, good and bad, why anyone might want to treat a worker's labour, and most people, consciously or unconsciously do, as a commodity.


The global terrestrial carbon cycle plays a pivotal role in regulating the atmospheric composition of greenhouse gases. Currently it is responsible for removing 25-30% of our emissions every year, an important ecosystem service that may not persist in the long term. Global warming tends to decrease the CO2 sink capacity of the world's oceans and ecosystems leading to a larger fraction of our emissions remaining in the atmosphere contributing to further warming, which in turn further decreases the sink capacity.
Here past, present and future variations and drivers of terrestrial ecosystem fluxes are analysed and projected. Uncertainties and robustness as well as their origin are assessed. It is shown that short term variations such as droughts significantly influence global fluxes even though occurring in limited regions. Additionally, seasonal changes may alter the present balance between uptake and release of carbon by stimulating the process of release of carbon through respiration dominating in the winter more than the photosynthesis and net uptake of carbon in the growing season. These variations may be more important for the carbon cycle than long term trends.
Ecosystem models represents powerful tools to further our understanding of the functioning of terrestrial ecosystems as well as allowing for projections of the potential future evolution of the carbon cycle. It is demonstrated that ecosystem models generally capture the main global spatial and temporal distributions of carbon fluxes. However, future projections are accompanied by large uncertainties, a result of a combination of uncertainties in climate predictions by climate models and uncertainties in the response of ecosystems to changes in the drivers. It is shown that uncertainties arising from differences in climate projections in terms of seasonal changes and short term variability dominate uncertainties arising from different scenarios of future atmospheric CO2 concentrations. Additionally, representation of sea surface temperature variations and especially variations associated with El Nino-Southern Oscillation in climate models stands out as particularly important for accurate predictions of future carbon fluxes.
Human activity contributes with a significant perturbation of the carbon-cycle and the climate system. Climate-economy models have the potential to supply direct policy-relevant estimates for climate mitigation. Here it is demonstrated that correct representation of the climate system and the carbon cycle in climate-economy models is important for making accurate estimates of future economy.


The modeling of the heart rate variability (HRV) found in the literature is most commonly based on the analysis of the interbeat time intervals in fre- quency domain or at discrete-time modeling. These approaches may fail if one is interested in generating the timing of the heartbeats. An alternative approach to model the HRV is the integral pulse frequency modula- tion (IPFM). The aim of this work was to evaluate a model of RSA based on IPFM, and a method to fit its parameters to experimental data. The transfer function H(s) between airflow and m(t), the modulating signal that represents the autonomic influences on the sino- atrial node, was modeled as a first order low-pass filter with DC gain G. The results showed that the model was able to recover the power spectral density partially at the frequency band of interest, and only part of HRV could be explained by the respiratory signal. Further studies are necessary to improve the model.


It is generally known that the phase center of a GNSS antenna is not a stable point. For any given GNSS antenna, the phase centers will change with the changing direction of the signal from a satellite. The problem is particularly important when different antennae are used in measurements. Ignoring these phase center variations in measurements can lead to serious vertical errors. The way to avoid these errors is by applying antenna phase center variation models in processing. Three major methods are presently available to determine mean antenna phase center offsets as well as variations of the phase center with elevation and azimuth for GNSS receiver antennas. Because of this and because of some problems in introducing of absolute models at present we can speak of three models of receiver antennas PCV (relative, absolute converted and absolute) and two of satellites antennas (standard and absolute). Additionally, processing simultaneously observations from different positioning systems e.g. GPS and GLONASS, we can expect a further complication resulting from different structure of signals and differences in satellites constellations. The aim of this paper is to study the height differences in short static GPS/GLONASS observations processing when different calibration models are used. The analysis was done using 24 hour GNSS data divided by one hour observation sessions. The results show that switching between different PCV models may have a visible effect on height determination, particularly in high accuracy applications.


(*) Notice: Subject to any disclaimer, the term of this patent is extended or adjusted under 35 U.S.C. 154(b) by 494 days. This patent is subject to a terminal dis-claimer. ABSTRACT A method, system computer program product recorded on a computer readable medium, for fast incremental backup of a storage device includes selecting an area of the data storage device for backup; creating the bitmap of data storage device; reading the selected area of the data storage device; converting data read from the data storage device into a usable format for the comparison of descriptors; reading descriptors oflogi-cal storage units of the selected area; discarding selected data access attributes of the descriptors; generating hash values for the descriptors; comparing the hash values of the descriptors of the logical storage units of the selected area with the hash values of the descriptors of previously archived logical storage units; for physical storage units related to logical storage units of the selected area whose hash values of the descriptors are identical to the hash values of the descriptors of the archived logical storage units, checking if these physical storage units need to be backed up; updating the bitmap of data storage device; and backing up contents of the physical storage units marked in the backup. The logical storage units can be files. The descriptors can be compared on a physical storage unit basis.


We always assume that our algebras are finite dimensional connected algebras over a field K. We furthermore assume that all algebras are non-semisimple, if nothing is stated otherwise. In this thesis we prove several new results about finite dimensional algebras and their dominant dimensions and related concepts. In the second chapter we start with the preliminaries. In [Abr], Abrar asked whether the dominant dimension of a non-selfinjective Nakayama algebra with n ≥ 3 simple modules is bounded by 2n− 3. In chapter three we show that 2n− 2 instead of 2n− 3 is the correct bound and generalize the statement to a much more general class of algebras, giving a proof of a conjecture of Yamagata for this class of algebras. We furthermore give formulas to compute the dominant and Gorenstein dimensions of Nakayama algebras that are Morita algebras in the sense of [KerYam]. In the fourth chapter we give a new characterisation of gendosymmetric algebras, which are algebras isomorphic to endomorphism rings of generators over symmetric algebras as first introduced in [FanKoe]. We show that an algebra is gendo-symmetric iff (A,D(A)) is a bocs. Further results include a description of the bocs module category and some new results about gendo-symmetric algebras using the theory of bocses. Chapter five gives a new method to construct gendo-symmetric (nonselfinjective) Gorenstein algebras from symmetric algebras. We give the general construction, including explicit values for the dominant and Gorenstein dimensions, and then specialize to symmetric Nakayama algebras for examples. Chapter 6 gives a new construction of an infinite series of algebras with dominant dimension at least two from any given finite dimensional algebra. We look at this construction in detail for gendo-symmetric algebras and give partial results about homological dimensions, which leads to a conjecture. We furthermore generalise the classical formulas τ ∼= Ω2 and τ−1 ∼= Ω−2 from the class of symmetric algebras to the more general class of gendo-symmetric algebras. The last chapter is about a conjecture of Hongxing Chen and Changchang Xi in [CX] stated there as conjecture 2. We give a counterexample to this conjecture.


The meagre input of scientists into the UK political process is often bemoaned. This lowers the level of debate on issues where special expertise is relevant – energy policy, global climatic change, and many other areas. When defence issues are involved, the pervasive secrecy is an extra impediment, but US experience shows that this need not prevent valuable debate.


Background Using antibody/aptamer-drug conjugates can be a promising method for decreasing toxicity, while increasing the efficiency of chemotherapy. Methodology/Principal Findings In this study, the antitumor agent Doxorubicin (Dox) was incorporated into the modified DNA aptamer TLS11a-GC, which specifically targets LH86, a human hepatocellular carcinoma cell line. Cell viability tests demonstrated that the TLS11a-GC-Dox conjugates exhibited both potency and target specificity. Importantly, intercalating Dox into the modified aptamer inhibited nonspecific uptake of membrane-permeable Dox to the non-target cell line. Since the conjugates are selective for cells that express higher amounts of target proteins, both criteria noted above are met, making TLS11a-GC-Dox conjugates potential candidates for targeted delivery to liver cancer cells. Conclusions/Significance Considering the large number of available aptamers that have specific targets for a wide variety of cancer cells, this novel aptamer-drug intercalation method will have promising implications for chemotherapeutics in general.


Introduction: Complete dentures are used for replacing the entire set of lost teeth in the dental arch. Regular oral and denture hygiene procedures play a major role in the maintenance of oral health and the long-term success of removable prosthodontic treatment. Aim: The aim of this study was to analyze the hygiene habits of complete denture patients in the local population of Indore. Materials and Methods: A descriptive, cross-sectional survey was conducted using a self-administered questionnaire involving the complete denture patients, and 459 denture subjects were assessed. Descriptive analysis was performed. Results: A total of 287 subjects cleaned their denture twice a day. Majority of the subjects used only water and toothbrush to clean their dentures. About 280 subjects do not have any reflex sensation while wearing the denture. Since the complete denture provides extensive support to the patient and withstands the masticatory force very effectively, a vast number of subjects do not take out their denture while eating. Conclusion: Several educational and motivational camps should be conducted to increase the awareness about denture cleanliness among the older subjects. Dentists should educate that microbial deposition on the tooth surface is harmful and instructs them to clean their dentures regularly.


Purpose: To describe the imaging features, the anatomic distribution and the surgical, and pathologic (histologic and immunoreactivity) findings of gastrointestinal stromal tumors (GISTs). Material and methods: Thirty nine patients with a diagnosis of GISTs (30 men and 9 women; mean age: 62.5 years old) were studied; they underwent US, CT and MRI studies. All patients were operated on and histologic and immunomarcation examinations were performed. Twenty patients were treated with tyrosine kinase inhibitor (TKI). Follow-up was done in 25 cases. Results: The tumor location in order of frequency was: stomach 26 cases (66.6%), small bowel 9 cases (23.1%) and rectum 4 cases (10.3%). The mean size of the tumors was 12.8 cm, 7 cm and 2.5 cm, respectively. US showed isoechoic solid lesions with a hypoechoic central area in relationship to necrosis or bleeding. The CAT revealed that the peripheral portion (solid) was contrast material enhanced while the central region was not enhanced (hypodense). With the MRI the solid tissue was hypointense in SET1, mild or moderately hyperintense in FSET2, while the central region was notably hyperintense in FSET2. After the contrast material injection the solid region showed a clear enhancement. Tumoral necrosis was observed in 74.5% of all tumors, 12.8% had air in its interior due to fistula, 12.8% was homogeneously solid (4 rectum tumors and one gastric tumor). Only 7/39 cases (17.9%) had metastases. In 19/20 patients (95%) treated with TKI after surgery diagnostic imaging studies showed no local relapse or distant metastases. Conclusion: Diagnostic imaging exams (US, CT, MRI) showed no GIST's pathognomonic patterns. The immunohistochemical study is required to achieve a final accurate diagnosis which enables a specific treatment.


We study the problem of the most economical representation of entangled states in the classical simulations. The idea is to reduce the general form of entanglement to the bipartite entanglement which has the short representation through Schmidt expansion. The problem of such reduction is stated exactly and discussed. The example is given which shows that if we allow the linear transformation (not only unitary), the general form of entanglement cannot be described in terms of bipartite entanglement. We also study the entanglement dynamics of 2 and 3 level atoms interacting randomly and find interesting dependence of the number of its excited levels.


Analgesia and sedation are essential for the care of children in the pediatric intensive care unit (PICU); however, when prolonged, they may be associated with iatrogenic withdrawal syndrome (IWS) and delirium. We sought to evaluate current practices on IWS and delirium assessment and management (including non‐pharmacologic strategies as early mobilization) and to investigate associations between the presence of an analgosedation protocol and IWS and delirium monitoring, analgosedation weaning, and early mobilization.


The closing months of 2008 saw the end of a chapter and the opening of a new one in the Western Sahara conflict. Over the past three years, the peace process in Western Sahara, what the United Nations considers Africa's last colony, was under the guidance of former Dutch diplomat Peter Van Walsum, who lost his position as UN Secretary General Personal Envoy at the end of August. Taking up where Van Walsum left off, the United States put forward the nomination of Ambassador Christopher Ross – one the US's leading Middle East diplomats – to mediate the three decades old dispute between the occupying power, Morocco, and the Sahrawi pro-independence movement, the Polisario Front. The change of leadership in the Western Sahara peace process in autumn 2008 came shortly before the election of Barak Obama to the US presidency. Since 2001, theGeorgeW.Bush administration had taken a decidedly pro-Moroccan stance on the issue of Western Sahara, one that grew more explicit approaching the end of his second term. Though Obama won the election on a pledge to revise the Bush administration's foreign policies, especially in the Middle East, it was still unclear – at the time ofwriting – whether the new administration in theWhiteHousewould also revise the US position on Western Sahara. As one of the most important Western powers with an interest in Western Sahara, next to France and Spain, yet with the power either to leverage or augment the stances of Paris and Rabat, the United States remains the linchpin to the (ir)resolution of the Western Sahara conflict.


The paper comprehensively interprets two novels by one of the most acclaimed Russian authors, Eugene Vodolazkin, which were published in Hungarian as well. The author of the article – as the Hungarian translator of the two texts – interprets Vodolazkin's works as the particular meeting place of various cultural codes. Including some of the aspects of postcolonialist literary criticism he concludes that the latent imperial point of view in the novels – due to the diversity of cultural codes – cannot be transferred into the translation.


Abstract The international response to the Taliban's sudden assumption of power in Kabul will make a critical difference for future developments in the country. Among the range of choices, a strong case can be made for engagement, dialogue and assistance. Immediate humanitarian need and widespread extreme poverty warrant substantial aid, including funds to maintain basic programmes established over the past two decades in health and education. The experience of international organisations working in Afghanistan during Taliban rule in the late 1990s constitutes a constructive precedent. Cooperation over aid is also an opening for a dialogue in which wider concerns can be aired. As in the late 1990s, sanctions and international isolation are likely to prove counterproductive by harming the Afghan people and strengthening the hardline factions of the Taliban.


2-Hydroxy cinnamaldehydes and acyclic N-sulfonyl ketimines were used as multisite substrates in an iminium catalysis triggered sequential process, leading to diverse chiral bridged polycyclic aminals in a highly regio- and stereoselective manner.


A DiscoveryI spent much of last spring researching the life of African American baseball player Bud Fowler, while preparing a paper about him for the annual Frederick Ivor-Campbell 19th Century Base Ball Conference, held in Cooperstown, N.Y., April 19-20, 2013. I was attracted to him for many reasons. He is credited with being the first African Amer- ican professional baseball player, whose career with otherwise mostly white baseball teams began in 1878 with a minor league in Massachusetts. He is the only baseball player of note to have grown up in Cooperstown. And his 30-year career in professional baseball was marked with unusual determination in the face of enormous racial discrimination. It was only after presenting my paper that I discovered that Bud Fowler had in 1912 also written, and copyrighted, a play entitled The Retired Black Planter, also published-for the first time-in this volume. This is the story of that discovery, and of that very amateur but sometimes fascinating play.Bud Fowler-A Black Barber Who Loved BaseballBud Fowler (1858-1913) was born as John W. Jackson in the Mohawk Valley town of Fort Plain, New York, and was brought as a baby to the almost exclusively white com- munity of Cooperstown, some fifty miles away on Lake Otsego, at the head of the Susquehanna River. His father, as well as his mother's father, were black barbers, members of a unique and almost forgotten group of African Americans that flourished during the 19th century. It was, indeed, as a black barber that Bud Fowler often earned his real livelihood in a day when even professional baseball rarely paid a living wage.Throughout most of the 1800s the craft of shaving and cutting the hair of white customers in America was dominated by African Americans-first often as slaves, and later as free men with a specialized trade that raised them into the tiny African American middle class. White men of means welcomed being shaved by polite and deferential blacks, the "knights of the razor" as they came to be called-despite the sharp, open razors with which they plied their trade. And the African Americans who shaved them learned to be polite-even when insulted; calm-even when angered; persistent-even when life grew difficult; and above all apparently subservient-even when they felt them- selves superior to those they served. These were lessons that Bud Fowler learned, and which served him well both as a baseball player and a barber.Black-owned and operated barber shops became scattered throughout American cities and large towns, where they served only white customers, often in surroundings of greater luxury than they could find at home. African Americans were either too poor to pay for barbering services, or were excluded by racial prejudice and segregation. And since each barber shop must serve a large number of customers, black barbers worked and often lived in otherwise white neighborhoods or communities. Their dominance in big cities gradually diminished after the Civil War, as Italian and German barbers brought their crafts with them from Europe, and as racial prejudice increased in America. They were forced to shift to serving the growing African American populations in big cities, or move for a time to smaller, white, interior communities like Cooperstown and towns in New York's Mohawk Valley. Between 1850 and 1900, the number of black barbers in New York's rural Otsego County rose from zero to 11, and then declined back to zero.Thus it was with Bud Fowler, who grew up and attended public school in the vir- tually all-white Village of Cooperstown, where his parents had moved about 1859, and where he learned the barbering trade from his father. He also learned to play, and to love, the baseball he played with his young white companions. Then in his late teens, under circumstances we still don't know, he left Cooperstown and made his way to Chelsea, Massachusetts, outside Boston, where by 1877 he was playing the baseball he loved with the amateur Chelsea Franklins team. …


The paper introduces the general methods for improving the transmitter-receiver isolation of velocity-measuring radar,and analyzes the problems existing in the metal-baffle method and the wave-absorbing materials method.A high impedance surface(HIS) of X band is designed to be applied to the velocity-measuring radar.Experimental results show that the HIS can remarkably decrease the transmitter-receiver mutual coupling up to 15 dB.


The article considers the calculation and spatial models of buildings with cylindrical-slab-guy covering and various constructive arrangement of the guy: radial, fan, parallel-transverse, parallel-longitudinal and longitudinal-transverse (cross). The calculations have been performed using the FEMAP / NX NASTRAN software package (PC), taking into account the geometric nonlinearity of the deformation.
The novelty of the research is a combined design of cylindrical-slab-guy covering. This is a complex of different types of coverings, overlapping large spans of buildings: the cylindrical shell of zero Gaussian curvature and the flat slab are located in the middle part; symmetric guy coverings are located at the edges.
The aim of the study is to assess the effect of guy system with various arrangement of guys on the stress-strain condition of cylindrical-slab-guy covering. The objective of the study is to provide a comparative analysis of the stress-strain condition of complex design of cylindrical-slab-guy covering and to select the optimal structural solution of the guy system under the same conditions (geometric parameters of the building, external loads and boundary fixings)


This brief summarizes findings on community ownership and control of lands in 13 countries in Latin America. These countries were included in RRI's global baseline of formally recognized indigenous and community land rights.


: We revisit the numerical computation of the baryon asymmetry from Cold Electroweak Baryogenesis given the physical Higgs mass. We investigate the dependence of the asymmetry on the speed at which electroweak symmetry breaking takes place. The maximum asymmetry does not occur for arbitrarily fast quenches, but at quench times of about (cid:28) q ' 16 m (cid:0) 1 H , with no asymmetry created for quenches slower than (cid:28) q > 30 m (cid:0) 1 H . Curiously, we also (cid:12)nd that the overall sign of the asymmetry depends on the quench time.


From an empirical point of view, it is increasingly clear that some standard assumptions in economic theory are unnecessarily restrictive to study the evolution and the changing structure of highly-dynamic industries (Dosi et al. (2016, 2017)). Thus, assuming full intertemporal rationality of representative agents, perfect (or even probabilistic) access to endogenously changing knowledge, or addressing the study of changing industries from the perspective of static equilibrium models is far from satisfactory. In this respect, a number of well-known theorists -during the last two decades- have been asking for a new approach to industrial dynamics which might consider the perspective of evolutionary models (Weibull (1995), Vega-Redondo (1996) y Sandholm (2010) and others). In this dissertation, we begin by presenting crucial concepts and results from the classical theory of games, and we connect them with very recent advances in evolutionary game theory. Afterwards, we show how this evolutionary approach allows us to propose an original model in which we incorporate boundedly-rational heterogeneous firms, which compete and learn in an oligopoly with imperfect information, and which fix prices according to routines, to capture market share. The demand-side of the market consists of consumers who are also asymmetrically informed, boundedly rational, and capable of learning and gradually adapting to the changing market options. We consider alternative pricing routines in the evolutionary model and we obtain formal results which we interpret and compare at the light of alternative results obtained from a standard non-cooperative game. This standard game (which we also analyse) involves full rationality of agents and perfect information. Somehow surprisingly, we find that in the fully rational standard setting, firms, either end up lowering prices and mutually destroying their extra-profits (a la Bertrand), or they may try to cooperate in a high-prices collusive equilibrium which, apart from being unstable, erodes consumer welfare. On the contrary, in the evolutionary (boundedly-rational setting) with imperfect information, firms get profits and co-exist by fixing moderate prices. This result suggests the possibility that, instead of being "market failures", such features as market power, heterogeneity facing radical uncertainty, and asymmetric information may be essential traits of markets,


Different cyclization products are formed with different Lewis acids in the ene cyclization of 5-hexenals (see scheme on the right; a: methylaluminum bisphenoxide, b: Me2 AlCl, c: Sc(OSO2 CF3 )3 ). This is not surprising, but it is gratifying that these result can be rationalized with an internally consistent model.


Objective To conduct epidemiological survey of unexpected injuries and deaths in children in Haikou City, Hainan Province and identify the risk factors for making preventing measures. Methods A prospective survey was conducted on severe unexpected injuries in 20 000 children aged 0~14 years from Jan.1, 1997 to Dec.31,1999 in Haikou City .The unexpected injuries and deaths were identified by using the ICD-10 coding classification system. Results The annual rate of severe unexpected injury was 210/100 000 children aged 0-14 years old and the morality rate was 20/100 000. Disability rate was 30/100 000. The unexpected death was the leading cause of death in the children (accounted for 40% of the total mortality) in this city. The major causes of deaths was traffic accidents,falling,drowning, poisoning. The major causes of severe unexpected injuries in children were in the order of falling, cutting injury, traffic accidents, drowning, burned/corroded, poisoning, The risks factors associated with severe unexpected injuries in children were sex (males), age (between the age of 7 to 14 years), environment (without awareness of traffic safety and precautionary measures. Conclusion Unexpected injury is a major health problem in children in Haikou City. Thus effective measures be taken for preventing unexpected injuries from occurrence to children.


The present invention relates to a device for measuring the activity of vertebrate spinal cord. The apparatus is formed so as to be fixed to the spinous processes of the vertebrae, comprising at least one of the main probe. The main probe includes at least one emitter emitting a spinal capable of interacting waves, receiving the waves interact with the spinal cord, and generates a signal indicating the spinal cord activity, and at least one associated receiver, vertebral characterized in that it is formed so as to hold the respective position of the side facing each other in. .The


A communication control method of a first terminal device, by which the first terminal device and a second terminal device located in the proximity of the first terminal device establish a direct communication path, the method being provided with: a step for monitoring a signal which the second terminal device transmits in order to cause proximal terminal devices to detect the second terminal device; a step for receiving the signal and detecting that the second terminal device is located in the proximity thereof; a step for acquiring coverage information indicating whether or not the second terminal device included in the signal is located within the range of an LTE base station; and a step for, on the basis of the coverage information, detecting whether or not the second terminal device is located in the range thereof.


The organizational device of constructing a unified model of active galactic nuclei is used to summarize recent work on a wide variety of relevant physical mechanisms. It is pointed out that only the grossest characteristics can be accommodated within the scheme. The suggestion is made that the primary properties of active galactic nuclei are basically controlled by three parameters, which can be chosen to be the black hole mass, the accretion rate, and the viewing angle. The radio galaxies are associated with holes which are accreting at levels far below the Eddington rate. The black holes powering radio galaxies are more massive than those in QSOs. The taxonomy of active galactic nuclei is considered along with the enery production by black holes. Emission mechanisms are discussed, taking into account radio sources, the power-law continuum, ultraviolet radiation, X-rays, and gamma rays. Attention is given to arguments in favor of relativistic beaming. 83 references.


The growth of CuGaSe2 films on a GaAs(100) substrate using cyclopentadienylcoppertriethylphosphine (CpCuTEP) as a Cu source in metalorganic molecular beam epitaxy (MOMBE) has been studied. Epitaxial CuGaSe2 films have been grown at 500°C with the c-axis normal to the substrate plane. Films were characterized by scanning electron microscopy, X-ray diffraction, photoluminescence and photoreflectance techniques.


Cobalt nanoparticles were synthesized using reduction of 60 Co gamma source with dose range 10-50 kGy in the presence of polyvinyl alcohol (PVA) polymer as a capping agent. Radiation synthesis has the advantages of without the use of reducing agent and catalyst and the cobalt nanoparticles aggregated immediately upon irradiation. The Ultraviolet-visible spectrophotometer and Nanophox measurement revealed the formation of cobalt nanoparticles by exhibiting surface plasmon absorption maxima at 500 nm. The size distribution of the cobalt nanoparticles was influenced by the concentration of CoCl2 and absorbed dose of gamma rays irradiation .


The article analyzes the monograph Essays on the History of Hydrochemistry in Ukraine (author Valentyn Khilchevskyi – professor at Taras Shevchenko National University of Kyiv), published in 2020.This is the first such monographic study. The monograph is devoted to the history of hydrochemical studies of surface waters in Ukraine. In the introductory part, an excursion on this issue was carried out in the XVIII-XIX centuries. The first part of the book is devoted to a review of hydrochemical studies of surface waters and their quality, which were carried out by Ukrainian scientists of the institutes of the National Academy of Sciences of Ukraine, industry institutions and institutions of higher education (1920-2020). As the author of the monograph notes, today scientific hydrochemical schools have been preserved at the Institute of Hydrobiology of the NAS of Ukraine (Kyiv), the Ukrainian Hydrometeorological Institute of the State Emergency Service of Ukraine and the NAS of Ukraine (Kyiv). They are engaged in hydrochemistry at the Ukrainian Institute of Environmental Problems (Kharkov). Among the higher educational institutions, it is worth noting the scientific hydrochemical school of the Taras Shevchenko National University of Kyiv, which has a prominent place in the development of the educational and methodological base, the creation of the first basic textbooks on hydrochemistry in Ukraine. They deal with individual issues of hydrochemistry at Odessa State Ecological University, Oles Honchar Dnipro National University, Yuriy Fedkovich Chernivtsi National University, Lesya Ukrainka Eastern European National University (Lutsk), National University of Water Management and Nature Management (Rivne).
The second part describes the formation and history of the scientific hydrochemical school of the Taras Shevchenko National University of Kyiv (1970-2020), to which the author himself belongs.
The information and facts presented in the monograph will be of extreme value from the standpoint of studying the history of hydrochemistry by young scientists, since today there is a reform in science and education, new concepts and terms are being introduced. For example, the nomenclature of the names of specialties is changing. So, the recruitment of graduate students of hydrologists-hydrochemists since 2016 is already carried out in specialty 103 "Earth Sciences" to the educational and scientific program "Hydrology". And from 2021, it is planned to completely switch to a new form of defense of dissertations (in particular, the degree of candidate of sciences will be replaced by the degree of Doctor of Philosophy).
The book will be useful to scientists and practitioners dealing with issues of hydrochemistry and water quality, teachers and students studying hydrochemical and hydroecological disciplines.


The fight against medicine counterfeiting is a current focus of the pharmaceutical world. Reliable analytical tools are needed to pursue the counterfeiters. Handheld devices present the advantage of providing quick results, with analyses possibly performed on the field. A large number of solid-dosage form medicines have been analyzed with a handheld Raman spectrometer. 33 out of 39 product families could be successfully analysed. The methods were validated with 100% of correct identification. Each product was additionally tested by the methods of the other products and successfully rejected. A second validation was performed using counterfeits, placebos, and generics. All the counterfeits were rejected, with values close to zero. Some generics presented a similar formulation to the brand products and were then identified as such. One placebo was positively identified, showing that low dosage products are difficult to analyze with Raman. Robustness tests were carried out, showing, for instance, that the operator has no influence on the results and that the analyses might be performed through transparent packaging. The discovery mode was also investigated, which proposes the chemical composition of the samples. The results demonstrated that the Raman handheld device is a reliable tool for the field analysis of counterfeits.


Background: Social media-based interventions are commonly used mode of delivery for physical activity promotion interventions. Instagram is an understudied social media platform and our purpose was to describe a detailed study protocol and report the feasibility of an Instagram-based physical activity promotion intervention. Method: Participants (n = 45) were recruited and randomized to follow one of three Instagram accounts for 3 months. The groups included a control, a popular fitness account, and two intervention groups. Participants were asked to complete weekly surveys for four weeks, at a 2-month follow up, and at a 3-month follow up. Participants were incentivized by being entered into a drawing for a free wearable activity monitor. Results: The intervention rate was 40% while the retention rate after four weeks was 33.3% and 22.2% after three months. Participants in the intervention groups reported higher education from the study account, enjoyment, and satisfaction. Conclusion: Although the study was well-received, more research is needed to determine how to increase retention within an Instagram-based intervention. Researchers should consider methods for participant identification, variations of interactive content, and extending the intervention period when designing their own study.


An important aspect of tristeza control in Brazil is the isolation and testing of new mild strains of Citrus tristeza virus (CTV) for use in preimmunization, since the protection this affords can sometimes break down. To evaluate the stability of the mild isolate obtained from Pera IAC sweet orange (PIAC isolate), this was graft-inoculated to different species and varieties of citrus. After 4 yr, the plants were evaluated by single strand conformation polymorphism (SSCP) of the coat protein gene. The SSCP profile remained unchanged only in Pera IAC and Mexican lime. To test the protection given by the isolate, plants that had maintained the original SSCP profile were challenged by cross-inoculation using the severe isolate Barão B. After 45 days, 6 mo and 1 yr, samples were again analyzed by SSCP, and the plants still showed the original profile, and had only mild symptoms. When exposed to natural aphid inoculation in the field, the Pera IAC plants retained the original SSCP profile even after 1 yr, and after 2 yr these trees showed no symptoms. We conclude that the PIAC isolate was stable and that it had protected the trees from severe field strains of CTV. Index words. SSCP, cross-protection. Brazil is the main world producer of sweet orange, accounting for 36% of global production (13). Citrus tristeza virus (CTV) became a major threat to Brazilian citriculture in the 1940s, when it attacked all combinations using sour orange as rootstock. Since finding that certain combinations of rootstock and sweet orange scion, as well as preimmunized clones, are more tolerant to this virus, the Brazilian citrus industry has lived with the disease, although today all trees are infected with CTV to differing degrees. In Brazil preimmunization with mild isolates has been used for many years for controlling stem-pitting isolates of CTV on sweet orange. The mild isolate used must have desirable characteristics such as stability in the host and no influence on plant development (5). Recently stem-pitting has occurred on preimmunized plants, and the SSCP profile of the CTV coat protein gene obtained from these plants was different from that of the mild isolate used for preimmunization, suggesting breakdown of cross-protection (10, 11). These results underline the need to find new isolates suitable for use in preimmunization. Most CTV isolates are actually a population of genetically related variants (4), and several approaches have been tested for the evaluation of such isolates. Single strand conformation polymorphism (SSCP) analysis provides rapid discrimination of DNA fragments of the same size but with variations in sequence, since small changes in sequence may alter the conformation of ssDNA and consequently its electrophoretic mobility. SSCP analysis using different genomic regions has been used to differentiate CTV isolates and monitor cross-protection between mild and severe isolates (1, 4, 6, 7, 8, 10, 11). We report here experiments with a mild CTV isolate obtained from Pera IAC sweet orange. We used SSCP to assess the stability of the isolate in different citrus hosts, and examined its ability to cross-protect against challenge by severe strains of CTV. MATERIALS AND METHODS Plant material and CTV isolates. The mild CTV isolate 'PIAC' was selected from an outstanding Pera IAC sweet orange/Rangpur 132 Fifteenth IOCV Conference, 2002—Citrus Tristeza Virus lime combination in a variety trial at the Centro APTA Citros Sylvio Moreira, Cordeirópolis, SP, Brazil (12). The Barão B CTV isolate was collected from a Barão sweet orange/ Caipira sweet orange combination; this isolate has previously been used as a severe CTV control (8, 14). Buds of shoot-tip grafted (virus free) sweet orange (cvs. Pera, Baia and Hamlin), Mexican lime, and Ponkan mandarin, were grafted on Rangpur lime rootstock. When the plants were 30 cm tall, two buds infected with PIAC were grafted into five virus-free plants of each species/variety. The plants were kept in a greenhouse at the Centro APTA Citros Sylvio Moreira. Four years later, samples of young bark were collected for CTV dsRNA purification. The Pera sweet orange and Mexican lime plants were challengeinoculated by grafting with buds containing isolate Barão B. Samples were collected 45 days, 6 mo and 1 yr later. Symptoms (average of three different plants) were scored on a 05 scale (0 = none, 5 = very intense) after 1 yr. Eight Pera IAC plants containing isolate PIAC were taken to the field; four to the orchard at the Centro APTA Citros Sylvio Moreira and four to the Capão Bonito experimental station, southern region of São Paulo, with the highest incidence of the severe Capão Bonito CTV complex. Samples collected after 1 yr were re-analyzed by SSCP and re-evaluated for symptoms. First-strand cDNA synthesis and coat protein gene amplification. Double-stranded RNA was isolated according to the procedure of Valverde et al. (15). This RNA was used as template for first-strand cDNA synthesis using random primers. The dsRNA was denatured at 75°C for 10 min and chilled on ice. The cDNA reaction was carried out at 37°C for 60 min, using M-MLV reverse transcriptase (GIBCO) (9). About 1/10 of the cDNA product was used for the polymerase chain reaction (PCR) to amplify the entire CP gene (p25 region) using specific primers (forward 5'ATGGACGACGAAACAAAG 3' and reverse 5'TCAACGTGTGTTGAATTT3') (3). Amplification was performed in 35 cycles of denaturation for 2 min at 94°C, annealing for 2 min at 55°C, and synthesis for 2 min at 72°C, followed by single chain extension for 10 min at 72°C. The products were analyzed on 1% agarose gels (electrophoresed at 100 volts for 30 min, stained with ethidium bromide and observed under UV light). SSCP analysis. This was done on the CP gene PCR product obtained. Usually 1-3 μl of the PCR reaction were mixed with an equal volume of denaturing solution (95% formamide, 20 mM EDTA, 0.05% xylene-cyanole and 0.05% bromophenol blue), heated for 10 min at 95°C, and chilled on ice. The denatured DNA was separated by electrophoresis using non-denaturing 8% polyacrylamide gels (16 × 20 cm × 0.75 mm BIO-RAD Protean 11 A) and 0.5 × TBE (10) as eletrophoresis buffer. A constant 200 volts was applied for 7 h, at 25°C. The gels were stained with silver nitrate (2).


"Art is the combination of objective real beauty and subjective creative beauty" is the basic theory of Chinese paintings.On the premise of insisting on "the mix of objective observing and spiritual apperceiving",the quality of flower and bird painting and artists' creativity can be enhanced through the lessons from the western character and method of field painting.If we insist upon the painting in our affection and spirit,we will experience the successful enjoyment of artistic creation.


The present invention relates to a liquid crystal display device and its driving method as well as reducing the integration driving the power consumption on the substrate. A pixel electrode connected to the liquid crystal display device according to the invention is formed for each zone is provided an intersection of the gate lines and data lines on the substrate and the thin film transistor, the thin film transistor connected in zigzag form on the basis of each of the gate lines, the pixel electrode and is connected to the common electrode, the common electrode forms a horizontal electric field to the liquid crystal panel having a common line are formed side by side along said gate lines; And a gate driver for supplying a scan pulse to the gate lines of the liquid crystal panel; And a data driver for supplying a pixel voltage to the data signal lines of said liquid crystal panel; It includes a common driver for supplying a common voltage signal of the alternating current form to the common line of the liquid crystal panel; The gate driver and the common driver is characterized by the integration on the substrate.


Cattle diet, marbling and wet aging can affect eating quality and consumer preference of beef. The objective of this study was to assess the relationship of cooked volatile compounds and consumer sensory traits of New Zealand grass-fed strip loin steaks in comparison to US grain-fed strip loin steaks from five different USDA quality grades, wet-aged for 7, 21 and 42 days. Beef strip loins (n = 200; 20 per USDA quality grade/fed cattle type) representing five USDA quality grades (USDA Prime, Top Choice, Low Choice, Select and Standard) and two fed cattle types (New Zealand grass-finished and US grain-finished) were used. Steaks were cooked to a target internal temperature of 71°C and served to consumer panelists (n = 600; 120 per five different cities in the US). Volatile analysis (n = 600) was performed on cooked samples, and quantitation was conducted by an internal standard calibration with authentic standards. Statistical analyses were conducted using the FACTOR procedure of SAS. A principle component analysis (PCA) showed relationships of volatile compounds, treatments, and consumer ratings. PC1 explained 17.17% of the variation and PC2 explained 10.96% of the variation. Consumer flavor liking was most closely associated with ethanol and treatments grass and grain Prime aged 42d. The majority of the alcohols and n-aldehydes were associated with the 7d grain treatments including grain Top Choice, Low Choice and Select. The Maillard derived compounds were grouped together and most associated with grass Top Choice 42d and the consumer attributes. Methional was closest to many grass treatments including grass Top Choice 7d, Low Choice 7d, Standard 7d, Prime 7d and Standard 21d. Although associations were evident between volatile compounds and consumer sensory attributes, they were not strongly related.


Microservices are an architectural style for software which currently receives a lot of attention in both industry and academia. Several companies employ microservice architectures with great success, and there is a wealth of blog posts praising their advantages. Especially so-called Internet-scale systems use them to satisfy their enormous scalability requirements and to rapidly deliver new features to their users. But microservices are not only popular with large, Internet-scale systems. Many traditional companies are also considering whether microservices are a viable option for their applications. However, these companies may have other motivations to employ microservices, and see other barriers which could prevent them from adopting microservices. Furthermore, these drivers and barriers possibly differ among industry sectors. In this article, we present the results of a survey on drivers and barriers for microservice adoption among professionals in Germany. In addition to overall drivers and barriers, we particularly focus on the use of microservices to modernize existing software, with special emphasis on implications for runtime performance and transactionality. We observe interesting differences between early adopters who emphasize scalability of their Internet-scale systems, compared to traditional companies which emphasize maintainability of their IT systems.


Bacterioferritin (EcBFR) ofEscherichia coli is an iron-mineralizing hemoprotein composed of 24 identical subunits, each containing a dinuclear metal-binding site known as the "ferroxidase center." The chemistry of Fe(II) binding and oxidation and Fe(III) hydrolysis using H2O2 as oxidant was studied by electrode oximetry, pH-stat, UV-visible spectrophotometry, and electron paramagnetic resonance spin trapping experiments. Absorption spectroscopy data demonstrate the oxidation of two Fe(II) per H2O2 at the ferroxidase center, thus avoiding hydroxyl radical production via Fenton chemistry. The oxidation reaction with H2O2 corresponds to [Fe(II)2-P]Z + H2O2→ [Fe(III)2O-P]Z + H2O, where [Fe(II)2-P]Z represents a diferrous ferroxidase center complex of the protein P with net charge Z and [Fe(III)2O-P]Z a μ-oxo-bridged diferric ferroxidase complex. The mineralization reaction is given by 2Fe2+ + H2O2 + 2H2O → 2FeOOH(core) + 4H+, where two Fe(II) are again oxidized by one H2O2. Hydrogen peroxide is shown to be an intermediate product of dioxygen reduction when O2 is used as the oxidant in both the ferroxidation and mineralization reactions. Most of the H2O2produced from O2 is rapidly consumed in a subsequent ferroxidase reaction with Fe(II) to produce H2O. EPR spin trapping experiments show that the presence of EcBFR greatly attenuates the production of hydroxyl radical during Fe(II) oxidation by H2O2, consistent with the ability of the bacterioferritin to facilitate the pairwise oxidation of Fe(II) by H2O2, thus avoiding odd electron reduction products of oxygen and therefore oxidative damage to the protein and cellular components through oxygen radical chemistry.


The report is devoted to common principles of training opticians in optical design at the level of qualification promotion. Curriculum structure and the peculiarities of the training are represented. The main attention is paied to using the computers on every stage of this process.


For generalized Reed-Muller codes, whenqis large enough, we give the second codeword weight, that is, the weight which is just above the minimal distance, and we also list all the codewords which reach this weight. To do this we have to study the number of points of some hypersurfaces and some arrangements of hyperplanes. We also present some properties of the Mobius function of these arrangements.


AbstractTwo roads diverged in a wood, and I—I took the one less traveled by, And that has made all the difference.


Significance The heme-thiolate peroxygenase of Agrocybe aegerita is a remarkably capable biocatalyst and a mechanistic analog of cytochrome P450. The stability of this fungal protein has provided a rare opportunity to study P450-like C−H hydroxylation in a novel and unrelated enzyme. Both APO-I and APO-II have been generated, and their redox potentials have been determined. The ferryl species Cys−S−FeIV−OH (APO-II) has been generated cleanly via reduction of the corresponding APO-I and a basic pKa revealed for the Cys−S−FeIV−OH ⇄ Cys−S−FeIV=O equilibrium. Most significantly, APO-II displays surprisingly high reactivity toward benzylic C−H (bond-dissociation energy 80−86 kcal/mol) and phenolic substrates with rate constants orders of magnitude larger than those of typical peroxidases or model compounds due to the basic ferryl. A kinetic and spectroscopic characterization of the ferryl intermediate (APO-II) from APO, the heme-thiolate peroxygenase from Agrocybe aegerita, is described. APO-II was generated by reaction of the ferric enzyme with metachloroperoxybenzoic acid in the presence of nitroxyl radicals and detected with the use of rapid-mixing stopped-flow UV-visible (UV-vis) spectroscopy. The nitroxyl radicals served as selective reductants of APO-I, reacting only slowly with APO-II. APO-II displayed a split Soret UV-vis spectrum (370 nm and 428 nm) characteristic of thiolate ligation. Rapid-mixing, pH-jump spectrophotometry revealed a basic pKa of 10.0 for the FeIV−O−H of APO-II, indicating that APO-II is protonated under typical turnover conditions. Kinetic characterization showed that APO-II is unusually reactive toward a panel of benzylic C−H and phenolic substrates, with second-order rate constants for C−H and O−H bond scission in the range of 10–107 M−1⋅s−1. Our results demonstrate the important role of the axial cysteine ligand in increasing the proton affinity of the ferryl oxygen of APO intermediates, thus providing additional driving force for C−H and O−H bond scission.


Exploitation of local red resources can enhance the attraction and coherence in college socialistic core value education.In Fujian,for example,its red resource possesses the connotation of socialistic ideology and can become new carriers and crucial wealth of college's core value education.Using red resources in college students' core value education requires some policies,such as gathering red resources and exploiting the carriers of core value education,utilizing red resources to consummate education's resources,and driving social practice and establishing spreading platform for red resources.


The present invention relates to a sound absorbing and insulating material using polyurethane foam of a waste sheet, and more particularly, to manufacturing a sound absorbing and insulating material by laminating a thermoplastic polymer on a sound absorbing material containing a polyurethane foam of a waste sheet. It can improve mechanical rigidity and sound insulation as well as eco-friendliness and cost savings of parts, and it is a polyurethane foam of waste sheets that can be applied to automotive parts such as package trays, luggage covering, covering shelves, and isolation pads. It relates to a sound absorbing and insulating material using the same and a method of manufacturing the same.


The interplay between molecular self-organization and molecular recognition leads to the construction of functional supramolecular systems in which order and mobility are combined and whose function is based on their organization. These fascinating phenomena, for which the living cell is a perfect example, can be understood only if a wide range of scientific disciplines work together. For this purpose, synthetic supramolecular systems can be used to simulate natural biomembrane processes. One example of this is the specific recognition and interaction between membrane-bound ligands and receptor proteins. Thus, the specific interaction of vitamin H (biotin) with the tetrafunctional protein streptavidin in the monolayer leads to 2D crystallization of the protein. Structural analysis shows that the protein is attached to the lipid membrane by two biotin-binding sites, leaving two still free. The opportunity this allows for biotinylated molecules to dock to the protein leads to interesting possibilities for constructing protein-containing functional multilayers. Another example for the simulation of biomembrane processes is the function of enzymes which is coupled to the recognition process. In the interaction of phospholipase A2 with lecithin monolayers, specific recognition between enzyme and substrate is followed by an active phase of lipid cleavage and then by aggregation of the enzyme to give domains of regular morphology. Fluorescence microscopy can be used to follow this process directly: an enzyme caught in action. Der Witz ist der Finder und der Verstand der Beobachter. Georg Christoph Lichtenberg11


Trust and the concept of the brand are increasingly of interest in the study of business relationships on the Internet. Synthesising studies of trust from other disciplines such as accounting, sociology, psychology and biology can provide useful insights into the application of trust both specifically and generally, to Internet business relationships. While there is a plethora of models, those with potential application for Internet business relationship theory are described and analysed. The argument is extended to discuss the concept of the brand as a surrogate for trust, and hence as a reliable identifier of a certain cluster of values.


Characteristics of second generation electroslag remelting and liquid metal electroslag casting technology has been introduced in this paper.Several research focuses of developing second generation electroslag metallurgy technology of large scale ingot have been put forward.Pointed out: to develop second generation electroslag metallurgy technology of large scale ingot for promoting autonomation of large scale forgings and development of nuclear power industry significantly.Not only pay attention to further develop electroslag remelting technology,but also pay attention to second liquid metal electroslag casting technology for large scale ingots.


We study the spectral constrained design of Multiple-Input Multiple-Output (MIMO) radar beampattern in an effort to the coexistence with the communication systems. We develop an optimization model relying on the minimization of beampattern Integrate-Sidelobe-Level (ISL) along with spectral, mainlobe width, Peak-to-Average Ratio (PAR) and energy constraints. To cope with the resultant non-convex problem, we introduce a novel polynomial-time iterative procedure that requires solving a series of constrained convex problems that evolve with each iteration. In particular, the proposed algorithm ensures that the monotonic decrease of ISL and the convergent solution is a KarushKuhnTucker (KKT) point. Numerical results are provided to assess the proposed algorithm in terms of the beampattern and spectral compatibility.


Abstract : Many applications exist for specialized coatings which must never debond during their working life. Ceramic coatings on metals are particularly important for this special category, but the dissimilar properties of the two types of materials make most existing coating techniques unacceptable. Ion implantation is well-known to produce totally adherent depositions of atoms, because the high energy of the ion beam causes the atoms to come to rest inside the target material rather than lay upon it. Thus, there is no discrete surface for debonding. Unfortunately, it has rarely been possible to accumulate enough ion implanted atoms in one place to form a pure layer because the sputtering coefficient is usually greater than unity. This research has developed a technique of codepositing a sacrificial layer together with ion implantation in order to create an effective sputtering coefficient of zero. Implanted atoms can accumulate to arbitrarily thick layers which are physically merged to the substrate. A demonstration of the general techniques has been performed using Zirconium as the ion. The Zirconium has been converted to zirconia, ZrO2, by reaction with a low pressure background of oxygen in the process chamber. The zirconia coatings show extreme adhesion using scratch testing and by repeated 600 deg C fast thermal cycling. Many observed properties as well as Auger analysis confirm they are ZrO2. Coatings were tested as a base layer for conventional ZrO2 coating technologies, and deposition on both flat and curved surfaces was demonstrated. Coating, ZrO2, Ion implantation, Adhesion.


We present a multipartite hashing protocol for distilling CSS states by means of local Clifford operations, Pauli measurements and classical communication. It is shown that this hashing protocol outperforms previous versions where only CNOTs are applied as local Clifford operations. Using the information-theoretical concept strongly typical set, we calculate the exact asymptotic yield of the protocol as the solution of a linear programming problem.


This paper analyze Co-education as a pedagogic model which incorporate Equality as a transverse axis. In an explicit and implicit way, Co-education prevent chauvinist violences, such as gender-based violence and LGBTI-phobia. An education system that, instead of encourage to critical analyses, it reproduces a differential and inequality socialization of genders and it does not act against said inequalities. Opposite to the androcentric and hegemonic existing model, Co-education as a pedagogy regards equality between genders as well as affective-sexual and gender diversity in educational institutions. Co-educating is to create a better world based in equality, diversity and respect, to construct a world in which chauvinist violence do not exist.


AIM: To study the effect of the serum containing Migu-Dalaoer pill(MDP) on the activity of osteoblast(OB) and osteoclast(OC) in their co-culture system.METHODS: OB was isolated from the calvaria of fetal SD rats by means of modified sequential collagenase digestion and OC was from the thighbone and shinbone of 1-day-old SD rats.OB and OC co-culture system was built under the condition of preventing these 2 kinds of cells from contact with each other and keeping the medium exchange free.The serum containing MDP at high,mediate and low doses was used to treat the OB and OC in the co-culture system.The osteogenic activity of OB was evaluated by MTT assay and determination of alkaline phosphatase(ALP) activity.The resorption activity of OC was investigated by observing the activity of tartrate-resistant acid phosphatase(TRAP) and the number of OC bone absorption lacuna.RESULTS: Compared with normal group,high and mediate doses of MDP significantly increased the OB quantity and the ALP activity,and significantly decreased the number of OC bone absorption lacuna and the TRAP activity at 6 d and 7 d in OB and OC co-culture system.CONCLUSION: The serum containing MDP promotes OB proliferationm and bone formation,and inhibits OC bone resorption in OB and OC co-culture system.


The large spatial variability in monsoon rainfall over India demands for regional models for predicting the seasonal rainfall. Hence, models were developed for predicting seasonal (June-September) rainfall of three regions (north, middle and south) of Gujarat using multiple regression technique. The monthly weather data of 30 years of Anand (1980-2009), 22 years (1987-2009) of Navsari and 27 years (1983-2009) of SK Nagar were used. The models were validated with independent data set of four year (2006-2009). The best models were selected based on higher R2 and lower model error. Four models were obtained; 2 for Anand (middle Gujarat) and one each for SK Nagar (north Gujarat) and Navsari (south Gujarat). Different models explained 74 to 93% variability in seasonal rainfall with models error ranging between -2.5 to 5.1%. During the validation period the performance of model was quite satisfactory with model error rainging between -12.6 to 2.6%. All the models were used to predict the rainfall for 2010 season. Results suggested that the rainfall would be higher than the normal rainfall in all the three regions. Navsari (south Gujarat) is expected to receive 1529.0 mm (14.5% higher than the normal), Anand (middle Gujarat) is expected to get 1294.0 to 1363.0 mm (62-71% higher) and SK Nagar (north Gujarat) is expected to receive 770.0 mm (40% above normal) rainfall during June to September period of year 2010. A major portion of annual rainfall over India is received during the southwest monsoon season (June–September) which is more or less stable with the mean seasonal rainfall (based on 1941–1990 data) of 89 cm and CV % of 10 (Rajeevan et al., 2006). However, even small fluctuation in the seasonal rainfall can have devastating impacts on agricultural sector at regional level. Thus forecasting of seasonal mean rainfall is therefore in great demand by the country's policy makers. In the past, attempts were been made to predict the total summer monsoon rainfall using empirical techniques involving local and global antecedent parameters that correlate with the monsoon rainfall. In the beginning of this century, Walker (1924) introduced an object technique of corelation for long range forecast and identified a few predictors from different parts of the world. Subsequently several antecedent meteorological parameters were identified and used for prediction (Jagannathan, 1960; Thapliyal and Kulshreshtha, 1992). In all these attempts a limited number of parameters were used, utilizing multiple linear regression technique. The accuracy of models was not always very satisfactory. The 16-parameter power regression and parametric models developed by Gowariker et al., (1991) were introduced operationally by IMD in 1988. The year 2002 turned out to be an all-India drought year with an overall rainfall deficiency of 19%, while model had predicted a normal monsoon, resulting in a lot of attention being focused on IMD's prediction methodology. The long-range forecasts models were subsequently modified and now IMD follows a two-stage forecasting strategy for long range forecasting of the south-west monsoon rainfall. The first stage forecast is issued in April for the south-west monsoon season (June


We examine long-term demographic forecasts to determine whether increases in the senior population will be followed by a decrease once the baby-boom generation passes. Planners may therefore need to flexibly assign resources to allow for future repurposing of investments. Forecasts in the U.S. and Canada indicate that the number of seniors in the population will plateau by the year 2045 with levels roughly maintained until at least 2060; thus, repurposing may be unnecessary. Increases in life-expectancy, immigration age structures, and echoes of the baby-boom generation in later years are expected to help maintain this plateau. While there is no observable decrease in the senior population by 2060, there is uncertainty around the expected rate of decline in health of this generation. Depending on this trajectory, community-level social supports could play a large role in maintaining senior health and independence as long as possible.


Traditional pricing of a cellular network operator considers the bandwidth utilization for users and operational cost. In this paper, we re-examine this critical subject through a holistic engineering view taken energy efficiency into account. We treat this issue as a two-stage Stackelberg game between the operator and mobile users, where the operator determines the price of unit bandwidth, and accordingly the users choose the amount of requested bandwidth to maximize their payoff. To reach a general result, randomly deployed base stations in large scale have been taken into consideration. By stochastic geometry, we derive the operator's profit and the energy efficiency per unit area, while considering the actual bandwidth demand of users based on their acceptable price. Simulation results show that the operator's profit and the energy efficiency can be achieved their maximum at nearly the same price (i.e., optimal price), and the optimal pricing strategy varies with the deployment density of base stations.


Vapor-liquid equilibria of methanol + hexyl acetate and ethanol + hexyl acetate mixtures were determined at 101.32 kPa. The data were checked for thermodynamic consistency using Fredenslund's test, correlated using Wilson, NRTL, and UNIQUAC equations for the liquid phase activity coefficients, and compared with the predictions of the group contribution methods UNIFAC and ASOG.


Children will have the chance to take their entrepreneurial skills from the classroom to the boardroom thanks to a renewed £300,000 in funding for Scotland's Enterprising Schools, First Minister Nicola Sturgeon has confirmed.


Nature apparently does a lot of computation constantly. If we can harness some of that computation at an appropriate level, we can potentially perform certain type of computation (much) faster and more efficiently than we can do with a von Neumann computer. Indeed, many powerful algorithms are inspired by nature and are thus prime candidates for nature-based computation. One particular branch of this effort that has seen some recent rapid advances is Ising machines. Some Ising machines are already showing better performance and energy efficiency for optimization problems. Through design iterations and co-evolution between hardware and algorithm, we expect more benefits from nature-based computing systems. In this paper, we make a case for an augmented Ising machine suitable for both training and inference using an energy-based machine learning algorithm. We show that with a small change, the Ising substrate accelerate key parts of the algorithm and achieve non-trivial speedup and efficiency gain. With a more substantial change, we can turn the machine into a self-sufficient gradient follower to virtually complete training entirely in hardware. This can bring about 29x speedup and about 1000x reduction in energy compared to a Tensor Processing Unit (TPU) host.


Taking College English Test Band 4(CET-4) as example,this paper probes into the main causes of the negative impact of high-stakes language testing.It is believed that the ambiguous objective of language testing,the contradiction between test objective and teaching objective,and the inconsistency of test contents and practical language use contribute most to the negative impact of testing.Instead of shirking the responsibility and shifting the blame onto the school and society,test developers can do a lot to reduce the negative impact by explicating the aim and limitation of the test,developing various reliable and validating language tests in accordance with the requirements and students and society.Meanwhile,the government,society and school should be well aware of the complexity of testing impact,and make use of language testing as a lever with care and scientific mind.


Abstract The reaction between maleic anhydride and rubber has been studied in solution, by milling and by heating in the solid phase. However, as is most often the case with chemical derivatives of the rubber hydrocarbon, the operating conditions that were employed only yielded products exhibiting considerable impairment to the physical properties characteristic of rubber (especially its high elasticity) as a result of secondary reactions of scission, cyclization and crosslinking. It has subsequently been shown that it is possible, under certain conditions, to minimize these injurious effects, both in the case of the reaction in solution between natural rubber and maleic N-methylimide and in that of the reaction by milling between synthetic olefinic elastomers and maleic anhydride. Inspired by these studies, we have undertaken to re-examine, on more precise chemical bases, the reaction between the rubber hydrocarbon and maleic anhydride.


The incidence of hydrogen bonds on NLO properties was not considered as essential, in particular in Pyridine Hydrazone systems, yet we show in the present work that a control of...