To the Editor: In a comprehensive and elegant review on long-acting injectable antipsychotics (LAIs) published in a recent supplement to the Journal, Correll et al reported that "education about the potential benefits of LAIs should be provided to clinicians and the health care team."1(p17) My colleagues and I agree with the authors that LAIs have been shown to reduce relapse compared to oral antipsychotics, but their prescribing patterns are not well known. A recent study conducted in Canada by my colleagues and I investigated prescribing determinants of LAIs among physicians treating schizophrenia using the Quebec drug plan (Régie de l'assurance maladie du Québec [RAMQ]) database. The RAMQ database also includes information on the insured person, such as age, gender, and region, and information on the physicians, such as the period of graduation. Patients with schizophrenia who were incident users of an LAI between January 2008 and March 2012 were selected. Schizophrenia diagnoses were considered confirmed if the last diagnosis related to psychiatric diseases (ICD-9 codes 290.0–311.9) recorded in the database was one of schizophrenia (ICD-9 code 295.x). In this study, 8,230 patients received at least 1 prescription for an LAI. Of these patients, 4,974 did not receive a prescription for an LAI in the year preceding index date (incident users). A total of 3,957 of them were covered by the RAMQ drug insurance for at least 1 year before and 1 year after index date. Finally, 1,996 patients were selected as patients with schizophrenia using an LAI. The general population consisted of a random sample of patients (N = 117,621) enrolled in the RAMQ database. Physician characteristics related to the prescription of the first LAI in the schizophrenia population and prescribing in the general population were compared using the χ2 test and with a base index of 100, where > 100 indicates an overrepresentation and < 100 indicates an underrepresentation in users with schizophrenia. Prescribers of LAIs for schizophrenia were more likely to graduate in 1990–1999 (index = 153, P > .001) compared to 1970– 1979 (index = 63, P < .001), more likely to practice in MontréalCentre than in other areas of Quebec (index = 147, P > .001), and more likely to work in both inpatient and outpatient settings (index = 338 and index = 391, respectively, P > .001) compared to prescribers for the general population. Data also showed that the use of atypical LAIs compared to typical LAIs was significantly higher (P < .001) among younger prescribers (graduation = 1990), in contrast with a significantly higher (P < .001) use of typical LAIs among older prescribers (graduation = 1979). The degree of prescribing LAIs appeared to be heterogeneous across the province of Quebec. In summary, LAI use was more common among recently graduated physicians and those in urban areas and working in both inpatient and outpatient settings.


A method, comprising: receiving (302) an input signal in a user equipment, the input signal comprising a desired signal and an interfering signal where the desired signal defines symbols using constellations; obtaining (304) information identifying a wireless channel used by the interfering signal and a modulation type used to modulate data in the interference signal; and retrieve (305) the symbols of the desired signal using the information; the method being characterized in that: obtaining information comprises: obtaining information using a precoding matrix indicator PMI, predefined sequence or a predefined reference signal demodulation DMRS; or obtaining the information through a control channel, a power level in the control channel set to a known value or a value within a known range.


ABSTRACT To determine if the GAD-7 provides incremental value, predicting a final diagnosis of an anxiety disorder after traumatic brain injury (TBI). Retrospective analysis of archival data of 100 patients with TBI, who underwent neuropsychological evaluation 1–12 months after injury. Receiver Operating Characteristic analysis determined the optimal cutoff point for clinically significant symptoms on the GAD−7. Hierarchical logistic regression analyses determined the relative contributions of premorbid psychiatric history, injury severity, and GAD−7 results in predicting a final diagnosis of anxiety disorder. GAD−7 cutoff point of ≥7 yielded the best combination of sensitivity and specificity regarding a final diagnosis of anxiety disorder. Within hierarchical logistic regression models, injury severity did not statistically significantly add to prior psychiatric history in predicting a final diagnosis of anxiety disorder. When GAD-7 was added, it made a statistically significant contribution in accounting for such a diagnosis and increased sensitivity from 71% to 91%. The GAD−7 holds diagnostic utility as a screening measure for anxiety disorders in patients with TBI. It should not be used in isolation but as part of a more comprehensive interview and history. The GAD−7 can benefit clinicians in assisting with timelier identification and treatment of symptoms of anxiety.


Features pertain to determining, at a client device, to send a query to a network access node. The query may be associated with a plurality of serving networks, each serving network identified with a serving network identifier. A first serving network identifier may be selected to associate with the query. The query may be sent to the network access node. The query may include the first serving network identifier, and in some aspects, a second serving network identifier. Additional features pertain to receiving, at a network node, a query including a first serving network identifier. The network node may be associated with a plurality of serving networks. A first server to which to forward the query may be determined at the network node. The first serving network identifier identifies the first server. The query may be sent to the first server.


Provides an historically based analysis of Afghanistan's current socio-economic situation and the implications of this for reconstruction and employment creation.


Simple Summary Decisions on cancer treatment for older patients take into account not only comorbidities but also physical and cognitive resources. Comprehensive geriatric assessment (CGA) in older patients assesses geriatric frailties but does not include standardized biological tests. The B12/CRP index (BCI) was first intended as a prognosis tool to predict 90-day mortality after advanced cancer diagnosis. This study shows the prognostic link between BCI value and overall cancer survival time in older people, and the association between BCI value and geriatric frailty before cancer treatment in this population. Abstract Background: While comprehensive geriatric assessment (CGA) in older patients treated for cancer assesses several related domains, it does not include standardized biological tests. The present study aimed to: (1) assess the prognosis value of the B12/CRP index (BCI) in a population of systemically treatable older patients with cancer and (2) analyze the association between BCI value and pre-existing geriatric frailty. Method: We conducted a retrospective observational study between January 2016 and June 2020 at Marseille University Hospital. All consecutive cancer patients aged 70 years and over before initiating systemic therapy were included. Results: Of the 863 patients included, 60.5% were men and 42.5% had metastatic stage cancer. Mean age was 81 years. The low-BCI group (≤10,000) had a significantly longer survival time than the mid-BCI (10,000 < BCI ≤ 40,000) and high-BCI (BCI > 40,000) groups (HR = 0.327, CI95% [0.26–0.42], p-value = 0.0001). Mid- and high-BCI (BCI > 40,000) values were associated with impaired functional status and malnutrition. Conclusion: A BCI > 10,000 would appear to be a good biological prognostic factor for poor survival times and pre-existing geriatric impairment in older cancer patients before they initiate systemic treatment.


The most significant technical solutions should be optimized using a technical and economic analysis, which reduces the cost of their implementation. Due to the fact that the diameter and height of the chimney depends on the gas velocity in the chimney, this parameter is decisive when carrying out a feasibility study. However, the existing methods and regulations in the Russian Federation concerning the construction and design of chimneys do not take into account all the necessary characteristics and parameters, for example, the economic component of determining the optimal gas velocity. PURPOSE of this article is to review foreign sources, in which consider similar issues and problems to take into account foreign experience in the development of a new methodology. METHODOLOGY. For the review, regulatory documents and scientific papers published in the most technically advanced countries were selected. RESULTS. In the course of analyzing the methodology for modeling the dispersion of impurities and calculating the height of the stack, it was concluded that, despite the large number of calculation models, the most accurate models are dispersion in air, based on meteorological data specific to a particular region. However, none of the considered methods for choosing the main dimensions of the stack is based on determining the optimal gas outlet rate based on the technical and economic analysis. The choice of the gas outlet rate is of a recommendatory nature and is mainly associated with the conditions for the formation of the initial section of the smoke plume and is not associated with the cost of the stack. The technique being developed in Russia makes it possible to take into account a wider range of chimney operating conditions, incl. and for the transitional phase to Green Energy, when the composition of combustion products will change depending on the proportion of hydrogen in the boiler fuel.


Emotions are present in practically every activity that we carry out. In religious discourse emotions, affections and feelings constitute ways of binding communities and providing ways of communicating and remaining united. In this article we discuss how emotions are mobilized in a religious radio program with a specific characteristic: the offer to the public of an emotional experience through the acquisition of a product.


T. Mersmann, A. Khoukaz,* M. Büscher, D. Chiladze, S. Dymov, M. Hartmann, V. Hejny, A. Kacharava, I. Keshelashvili, P. Kulessa, Y. Maeda, M. Mielke, S. Mikirtychiants, H. Ohm, M. Papenbrock, D. Prasuhn, F. Rathmann, T. Rausmann, R. Schleichert, V. Serdyuk, H.-J. Stein, H. Ströher, A. Täschner, Yu. Valdau, C. Wilkin, and A. Wrońska Institut für Kernphysik, Universität Münster, 48149 Münster, Germany Institut für Kernphysik, Forschungszentrum Jülich, 52425 Jülich, Germany High Energy Physics Institute, Tbilisi State University, 0186 Tbilisi, Georgia Laboratory of Nuclear Problems, JINR, 141980 Dubna, Russia Physikalisches Institut II, Universität Erlangen-Nürnberg, 91058 Erlangen, Germany H. Niewodniczanski Institute of Nuclear Physics PAN, 31342 Cracow, Poland Research Center for Nuclear Physics, Osaka University, Ibaraki, Osaka 567-0047, Japan High Energy Physics Department, Petersburg Nuclear Physics Institute, 188350 Gatchina, Russia Physics and Astronomy Department, UCL, Gower Street, London WC1E 6BT, United Kingdom Institute of Physics, Jagiellonian University, 30059 Cracow, Poland (Received 29 January 2007; revised manuscript received 12 April 2007; published 13 June 2007) The differential and total cross sections for the dp! 3He reaction have been measured in a high precision high statistics COSY-ANKE experiment near threshold using a continuous beam energy ramp up to an excess energy Q of 11.3 MeV with essentially 100% acceptance. The kinematics allowed the mean value of Q to be determined to about 9 keV. Evidence is found for the effects of higher partial waves for Q * 4 MeV. The very rapid rise of the total cross section to its maximum value within 0.5 MeV of threshold implies a very large 3He scattering length and hence the presence of a quasibound state extremely close to threshold.


The utility model discloses an elastic bar hold that is convenient to forcibly detach a bit, comprising a spring pocket, a milling cutter, a back screw cap, a clamp and a strengthening cap. A gasket is arranged on the male cone of the spring pocket. With the back screw cap unscrewed, the strengthening cap is driven to make the gasket forcibly pull the spring pocket out of the clamp. After the strengthening cap is retracted, the milling cutter can be removed and replaced. The utility model, which is easy to be operated, has simple structure and high accuracy, thus preventing the damage of a knife tool resulting form the removal of the milling cutter, which requires an operator to strike the clamp. So the utility model illustrates a good prospect of application and extension.


We report for the first time an extended series of correlated origin independent calculations of nuclear magnetic shieldingtensors using the approach of continuous transformation of the origin of the current density to annihilate its diamagnetic contribution. A systematic study was undertaken to develop optimal basis sets for H, C, N, O, F correlated nuclear magnetic shieldings, looking for the best compromise between accuracy and size. Beyond Hartree–Fock calculations were carried out at two levels of accuracy, the multiconfigurational self-consistent field based on the complete active space scheme, and the second-order polarization propagator approximation (SOPPA). In addition we present the first shielding calculations employing the second-order polarization propagator approximation with coupled cluster singles and doubles amplitudes SOPPA (CCSD).


DOI: 10.21276/sjbms.2018.3.6.8 Abstract: This study aims to analyze financial performance of PT. Bank Bukopin Tbk, before and after conducting "Laku Pandai" (branchless banking), while the long-term goal is modeling the assessment of financial performance strategy of branchless banking in Indonesia. The method used in this research is RGEC (Risk Profile, Good Corporate Governance, Earning, Capital). The assessment financial performance of PT. Bank Bukopin Tbk before and after the application of branchless banking is not difference and not significant, but is not fixed value


Introduction: Angrite constitutes one of the oldest basaltic achondrite groups and shows ususual mineral assemblages due to depletion in alkaline elements and enrichment in refractory elements [1]. Angrites lack shock metamorphism except for NWA 1670 and NWA 7203, and are therefore widely employed as useful time anchors [2]. In our previous study we reported shock metamorphism in NWA 7203 and suggested the importance of this sample to understand the evolution of the angrite parent body [3]. NWA 7203 shows a quenched texture and its grain size exhibits large variations, but the formation process of this texture is unclear [4]. In this study, we performed detailed mineralogy of NWA 7203 in order to clarify the crystallization history of this interesting angrite. Results: NWA 7203 is mainly composed of dendrites consisting of intergrowth of olivine and anorthite, and pyroxene fills in between the dendrites. Grain size varies from fine grains (~1 μm) to coarse grains (>100 μm) (Fig. 1). The fine-grained areas show radial textures that grew into coarse-grained areas. We estimated bulk compositions of both fine-grained and coarse-grained areas by EPMA grid analyses of each area. The bulk composition of the finegrained area is slightly more Fe-rich (SiO2=41, Al2O3=14, FeO=23, MgO=7, and CaO=15) than that of the coarsegrained area (SiO2=41, Al2O3=15, FeO=21, MgO=7, and CaO=15) (all in wt%). Olivines (except xenocrysts) in the fine-grained area are Fo54-4, while those in the coarse-grained areas are Fo59-0, which is consistent with more magnesian bulk composition of the coarse-grained area. On the other hand, pyroxenes in the fine-grained area are Mg#=0.50-0.22, while those in the coarse-grained area are Mg#=0.44-0, which is different from the olivine result. We found rare Mg-rich olivine grains (Fo64, size: ~0.1 mm) in the fine-grained area. One such a grain shows a blade shape (~1 mm long, ~20 m wide) intergrown with anorthite with the core of Mg-rich olivine (Fo64) (Fig. 1). Discussion and Conclusion: The texture of NWA 7203 (e.g., large variation of grain sizes) is unusual and could not be formed by simple fractional crystallization because coarse-grained areas are more Mg-rich than fine-grained areas. It is texturally evident that fine-rained areas first crystallized and coarse-grained areas subsequently formed as shown by the radial texture in the fine-grained areas. This is contrary to what is observed for olivine compositions since olivine is more Mg-rich in coarse-grained areas than fine-grained areas. Another important observation is the presence of Mg-rich olivine grains in the fine-grained areas. We interpret that they are xenocrysts as found in other quenched angrites. However, the texture of NWA 7203 olivine xenocrysts are different from other samples and Cr2O3 is not so high (up to 0.1 wt%) unlike other angrites' xenocrysts (e.g., Asuka 881371: mm-sized large grains and >0.3 wt% Cr2O3) [5]. We consider the crystallization history of NWA 7203 as follows (Fig. 2). First, finegrained areas rapidly crystallized with Mg-rich olivine xenocrysts as crystallization seeds, and then coarse-grained areas were subsequently formed. However, it is required to consider some process to change the melt composition of the coarse-grained areas into more Mg-rich than that of the fine-grained areas. One explanation is the incorporation of Mg-rich melt (e.g., magma mixing) because coarse-grained areas have more Mg-rich bulk composition.


Tropical Storms Irene and Lee in 2011. Superstorm Sandy in 2012. The frigid, snowy winter of 2013-2014. While it is tempting to blame individual events on climate change — or lack of it — direct cause and effect cannot be established for specific events. What can be said is that the trend toward more extreme weather fits with the predictions of climate scientists, and that longterm data display abundant evidence of a warming Hudson Valley.


It has become a sort of fashion, among those who write about the therapeutic value of heat, to trace it back to the Romans and the Greeks. What a tremendous burden of responsibility has been thrown on the Romans and the Greeks for so many things sacred or profane! During the height of the Roman Empire there were, in Rome proper, a large number of public bathing establishments, some of which were enormous and imposing institutions, such as the baths of Caracalla and those of Diocletian. The baths of Caracalla, for instance, occupied a building almost 1,200 feet square. In this mammoth structure were a series of pools, in each of which the water was kept at a different temperature from hot to cool; in each pool the temperature of the water was maintained by special heating arrangements. Besides these pools there were rooms for epilation, for massage and for


In order to ascertain prediction index critical value of working faces in Gaocheng mine,using experience formula of gas desorption index and gas stress fix Δh2 critical value,with the experiment method and analyzed the critical value′s reliability,through Δh2 and gas content relation curve,which was tested on the spot.The practice proved that Δh2 critical value which was fixed by experiment method can not only insure safety of working place but also bring back good economic benefits.


This study aims to determine the regional financial performance of Badung Regency in the implementation of regional autonomy. The study used secondary data obtained from the Regional Government Financial Reports of Badung Regency. Researchers conducted an analysis of financial performance with indicators of regional financial independence, efficiency and effectiveness in the 2015-2019 period. The results of the study found that 1) The level of financial independence of the Badung Regency area was classified as very good with a ratio value of 489.8 percent. 2) The level of the financial efficiency ratio of the Badung Regency Government is in the very effective criteria with an efficiency ratio value of 3.59 percent. During a period of five years the financial efficiency of the Badung Regency Government has increased in terms of the percentage ratio, although in 2019 it decreased by 1.62%, but based on the financial efficiency criteria, the Badung Regency Government is still in the very efficient criteria; and 3) The level of financial effectiveness of Badung Regency is in the effective criteria with an effectiveness ratio of 95 percent.


This paper presents the ongoing research at the Swiss Federal Institute of Technology (ETH), Zurich, related to the design and implementation of an IDSS (integrated decision support system) dedicated to integrated risk assessment and safety management with application to the transportation of hazardous substances. One of the goals is to construct advanced models to estimate (a) the optimal routing for transportation of hazardous substances and (b) optimise plans for emergency preparedness and management in case of potential (severe) accidents. As an output of this activity one aims at designing tools to represent risk to the public by using a GIS calculation platform, generically applicable to Switzerland. Though a database of some 700 chemicals is available, epichlorohydrin is the hazardous substance targeted in the first phase.


The Nuclear Data Team has released a multitemperature transport library, MT71x, based upon ENDF/B-VII.1 with a few modifications as well as additional evaluations for a total of 427 isotope tables. The library was processed using NJOY2012.39 into 23 temperatures. MT71x consists of two sub-libraries; MT71xMG for multigroup energy representation data and MT71xCE for continuous energy representation data. These sub-libraries are suitable for deterministic transport and Monte Carlo transport applications, respectively. The SZAs used are the same for the two sub-libraries; that is, the same SZA can be used for both libraries. This makes comparisons between the two libraries and between deterministic and Monte Carlo codes straightforward. Both the multigroup energy and continuous energy libraries were verified and validated with our checking codes checkmg and checkace (multigroup and continuous energy, respectively) Then an expanded suite of tests was used for additional verification and, finally, verified using an extensive suite of critical benchmark models. We feel that this library is suitable for all calculations and is particularly useful for calculations sensitive to temperature effects.


Oral premalignant lesions (OPLs) that affect approximately 4.5% of the world's population usually precede the occurrence of Oral squamous cell
carcinoma. These lesions are now included in oral potentially malignant disorders (OPMD). Majority of OPLs regress, yet, up to 30% of them
ultimately progress through increasingly grades of dysplasia &culminate as oral cancer. Therefore, OPLs represent an intermediate phase during
the evolution of normal mucosa into malignant tumor, owing to their acquisition of a subset of the genomic alterations from those necessary to
develop into Oral Squamous cell Carcinoma(OSCC).(1) In India OSCC is responsible for more than 20% of new malignancies diagnosed every
year, being the most prevalent malignancy in the nation. There are several prognostic factors which help to evaluate the risk associated with the
OSCC and serve as subsequent treatment guidelines. Increasing evidence has, so far, suggested that inammation may be linked to pathogenesis of
oral cancer. Also, the tumor microenvironment is considered a crucial component in the understanding of the biologic behavior of a neoplasm.
Leukocytosis is common in patients with progressive oral squamous cell carcinoma, is related with T-classication, lympho-vascular permeation,
and recurrence or metastasis, &, therefore could decrease survival. Tumor-related leukocytosis results from hematopoietic colony-stimulating
factors and inammatory cytokines from solid tumors. (2,4) One of the new most promising histopathological factor in prognostic evaluation of
OSCC is, the density of tumour inltrating lymphocytes (TILs). Different subsets of lymphocytes have different or even opposing functions in
the tumor microenvironment. (2,6,7) Neutrophils contribute to cancer progression or regression via multiple mechanisms, including the
suppression of cytotoxic as well as helper Tcell responses and the stimulation of tumor angiogenesis.(8) B cells also act as antigen-presenting cells,
promote differentiation of Th1 cells and Tcyt cells, and directly kill cancer cells through release of Granzyme B, thus, having a tumor suppressive
role. (9) Inltrating eosinophils in the tumor microenvironment (TME), supply direct and indirect mitogenic growth mediators that stimulate
proliferation of neoplastic cells, as well as educate other stromal cell types to induce paracrine and juxtacrine mitogenic signaling molecules to
support neoplastic growth which also appears true for oral squamous cell carcinomas (OSCCs). (10) The plasmacytoid dendritic cells (pDC), are
specically important in cancer immunity as, these cells have been identied in many solid malignant tumors, including those of head and neck &
may play a key role in tumor occurrence and development.(9,12) Mast cells have a long life and form a heterogeneous population of cells that seem
to have both a positive and negative regulatory effect on the immune system. MCs accumulate into tumor microenvironment by the help of tumor
cell-released chemoattractants such as SCF or CCL15 and actively recruit cells of the innate immune system mainly neutrophils, macrophages, and
eosinophils and cells of the acquired immune system (B and T cells) to orchestrate antitumor immune responses (13) In cancer tissues, the
inltration of macrophages is signicantly increased. Macrophages are recruited to this edge by tumor-derived chemotactic agents and are a major
inltrating cell type in the leading edge of a carcinoma.(16) OSCC are highly immunogenic tumors that are often characterized by abundant
inltration of immune cells, however, their function & prognostic value vary. (19, 20)


The invention discloses a bactericide composition containing difenoconazole and levorotatory alpha-terpineol. The bactericide composition is characterized by comprising effective components of 1% to 50% by weight of difenoconazole and 1% to 50% by weight of levorotatory alpha-terpineol, and is mainly used for preventing and treating sigatoka. The invention has the advantages of obvious synergy function after formulation, obvious reduction of the usage amount and the usage frequency of the bactericide, lower cost and drug resistance of plant disease deferment. Meanwhile, the levorotatory terpineol as monoterpene alcohols prepared by compounding natural renewable resources can be degraded easily in environment, and meets environment friendly requirement. Moreover, micro-emulsion and aqueous emulsion relevant to the invention replace organic solvent with water portion, and environment pollution is reduced as well.


[Abstract]Over the past 15 years, significant sectors of the mining industry have undertaken the Global Mining Initiative. This was followed by an extensive program called the Mining, Minerals and Sustainable Development Project. These self regulatory mechanisms require 'beyond compliance' environmental behaviour, whether companies are operating in the developed or the developing world. Reviewing case studies of gold mines operated by the 'top tier' transnational mining companies in Queensland, Papua New Guinea and Tanzania, this thesis addresses whether these and other self regulatory mechanisms are more important than formal legislation in motivating compliance with environmental laws for these mining companies.


We describe how the theory of complex multiplication can be used to construct elliptic curves over a finite field with a given number of rational points and illustrate how this method can be applied to primality testing.


It is widely supposed-in the author views correctly-that the five romantic Greek novels, by Xenophon, Chariton, Longus, Achilles Tatius, and Heliodorus, are more or less cut from a similar piece of cloth. Sophie Lalanne has recently stated: "Tous les romans grecs racontent la meme histoire d'amour et d'aventures, avec des variants qui, bien que nombreuses, ne modifient pas la structure d'ensemble". Two such tales concerns us, both datable to the fifth century: the Acts of Xanthippe and Polyxena , and more particularly the latter part centering on Polyxena, which is closer in structure to the Greek romantic novels; and the Acts of Philip. The author have traced the theme of evil returned for evil to indicate how, over the course of his travels, Philip learns the deeper meaning of Christian mercy and the obligation to requite harm with good. Keywords: Achilles Tatius; Chariton; Christian Acts; Greek Novels; Heliodorus; Longus; Philip; Xenophon


BACKGROUND
Li-Fraumeni syndrome (LFS) genetic testing is performed using blood specimens from patients selected based on phenotype-dependent guidelines. This approach is problematic for understanding LFS clinical spectrum, because patients with non-classical presentations are missed, clonal hematopoiesis (CH)-related somatic blood mutations cannot be distinguished from germline variants, and unrelated tumors cannot be differentiated from those driven by germline TP53 defects.

METHODS
To provide insights into LFS-related cancer spectrum, we analyzed paired tumor-blood DNA sequencing results in 17,922 cancer patients, and distinguished CH-related, mosaic, and germline TP53 variants. Loss-of-heterozygosity (LOH) and TP53 mutational status were assessed in tumors, followed by immunohistochemistry for p53 expression on a subset to identify those lacking biallelic TP53 inactivation.

RESULTS
Pathogenic/likely pathogenic TP53 variants were identified in 50 patients, 12 (24.0%) of which were CH-related and four (8.0%) were mosaic. Twelve (35.3%) of 34 patients with germline TP53 variants did not meet LFS testing criteria. LOH of germline TP53 variant was observed in 96.0% (95% CI = 79.7-99.9%) of core LFS-spectrum type tumors versus 45.5% (95% CI = 16.8-76.6%) of other tumors, and 91.3% (95% CI = 72.0-98.9%) of tumors from patients who met LFS testing criteria versus 61.5% (95% CI = 31.6-86.1%) of tumors from patients who did not. Tumors retaining wild-type TP53 allele exhibited wild-type p53 expression.

CONCLUSIONS
Our results indicate that some TP53 variants identified in blood-only sequencing are not germline and a substantial proportion of LFS patients are missed by current testing guidelines. Additionally, a subset of tumors from LFS patients do not have biallelic TP53 inactivation and may represent cancers unrelated to their germline TP53 defect.


In this contribution we present investigations about the use of computational intelligence for quantitative structure-activity relationships, in particular for the prediction of aquatic toxicity of pesticides. Different molecular descriptors quantify structural aspects of molecules, especially their toxic activity. Hence the correlation behavior of the different descriptors in the descriptor space is studied for the prediction of toxicity. In a first step 164 pesticides are considered and 175 descriptors are taken into account; moreover, subclasses of the whole set of data are investigated. From these data sets results using genetically optimized multi-layer perceptrons, B-spline networks and a method to function approximation by a neuro-fuzzy model are compared.


For eight years (1872‒1880), S.P. Botkin served as the private physician of Empress Maria Alexandrovna who suffered from pulmonary tuberculosis. The particular details of this clinical case were defined by its unique deontological aspects: a doctor, a famous professor, a recognized expert Europe-wide, was also a subject of the royal patient – his prescriptions were dependent on her wishes. Medical recommendations were often met with resistance, since due to her deep religiosity, the empress had no motivation to seek treatment. The long-term illness and the particular circumstances of the family background (the existence of the emperor's second family) contributed to the fact that the relationship between the physician-in-ordinary and the empress was not confined to his official duties. Botkin sympathized with Maria Alexandrovna and understood that her spouse(cid:25)s behavior was causing her distress; he was grateful for his participation in family affairs. The foundation of the empress(cid:25) attitude to Botkin lay in her Slavophile sentiment. It was significant that the authority of the court physician convinced society of the opinion that the royal couple(cid:25)s separation was due to the state of the empress(cid:25) health. His professional enthusiasm, ability to influence the psyche and non-conformism – unusual for a royal household member – generated goodwill in the uncompliant patient, which largely ensured successful treatment. Botkin(cid:25)s presence let the patient realize her need for care.


Lung infection is common after near drowning, especially if brackish water has been aspirated. Embolism of infected material from the lungs to the arterial tree may result in brain abscesses or death from systemic aspergillosis. Blood should be cultured from all patients who have aspirated water. Leptospirosis has been reported after immersion in lakes or reservoirs, possibly due to ingestion of water contaminated with rats' urine. Outpatient follow up with a chest radiography after two weeks is advisable for all patients who have been immersed in water, irrespective of their clinical state on admission.


Of the several criteria by which Americans are stratified, none bears greater significance than skin color. The rigidity of norms separating blacks and whites still approaches that of a caste system. One obvious reason for the significance of skin color as a basis of social stratification is the ease with which it may be applied. Where color has been used extensively as a basis of discrimination, it becomes an appropriate surrogate for other, more functional criteria of stratification such as education, occupation, and income. A number of empirical sociological studies have demonstrated the fact that within both groups created by application of the color criterion is further social stratification. As is true for the white population, so within the black population there has developed a system of stratification based on such criteria as family, occupation, income, and education. Drake and Cayton (1962), among others, describe distinctly different life styles within these segments of the black population. Frazier (1932), Duncan and Duncan (1957), Schnore (1965), and Edwards (1970) are among those who have provided empirical evidence of residential


Aquificales are metabolically versatile chemolithoautotrophic thermophilic bacteria. This group is widespread in both deep-sea and terrestrial hydrothermal systems. In Yellowstone National Park, they were first described in early descriptions of the biology of the park, and later captured the attention of many microbiologists including Brock, Stahl, Pace, and others. There are four genera currently described from Yellowstone: Thermocrinis, Sulfurihydrogenibium, Hydrogenobacter and the only acidophilic genus, Hydrogenobaculum. Aquificales appear to fix CO2 using the reductive TCA cycle, although several species can also obtain carbon from organic sources such as acetate and formate. Hydrogen and sulfur appear to be the preferred electron donors. Furthermore, many of these filamentous bacteria are associated with visible iron and sulfur mineral precipitation, which points to their overall importance in biogeochemical cycling in hot spring ecosystems.


Ash power from electrical plant was smashed to microm grade. It was incorporated into EPDM rubber and then smelted. This smelted rubber was blended with PP at high temperature in the twin screw extruder. The resultant modified PP was injected into standard bars. The impact strength and tensile strength were measured. It was found that the impact strength of modified PP was improved greatly, at the same time the addition of ash power could contribute to the tensile strength. The rheological property and the processing character kept almost no changed.


We surveyed a pool of 433 students at the University of Banja Luka in Bosnia and Herzegovina during April 2010, examining users' perceptions about mobile phones security. The main research hypothesis validated was that users are unaware of the necessary measures to avoid a possible unauthorized access and/or sensitive data retrieval from their phones and that they lack proper security education. Most of the results proved to be non-country specific, revealing that users feel mobile phone communication is not secure. We further present the results about users' security practices regarding mobile phone usage.


In ICID, 15th International Congress on Irrigation and Drainage, The Hague, The Netherlands, 1993: Water management in the next century. Transactions: Vol.1-A, Question 44, RI-R35: Planning and design of irrigation and drainage systems


The functionalized process refers to a new concept, which aims to modify the physical and chemical properties of the original surface for specific purposes. Hence, the functional surfaces will introduce the desired properties that can not be found in the original material. The various applications might be named liquid repellent, anti-icing, anti-reflection, water harvesting, anti-biofouling, etc. This study proposes a simple and fast fabrication method based on etching incorporated with low surface energy chemical compound coating to functionalize the Iron (Fe) surface for omniphobic and anti-icing characteristics. After being functionalized, the surface reveals an omniphobic state with various liquids and extremely low adhesion to ice bulk. The research might suggest solutions for manufacturing functional surfaces oriented to outdoor applications such as windshields, rearview mirrors, anti-fouling surfaces, etc


Claims demanding money or additional services due to damages allegedly caused by negligent performance of professional services are a fact of life in the engineering consulting business. But how your firm manages these claims can impact its profitability, in terms of the indirect, unreimbursed expenses incurred when responding to a claim; the critical time lost in managing the professional practice and strategic direction of the firm; and the emotional trauma experienced by everyone involved. Effective claims management requires little more than common sense, good business judgment and the resolve to stay involved in the process. This article briefly outlines the steps a firm should take in the immediate aftermath of a claim and what it should avoid doing (e.g., admitting any liability or responsibility for the alleged damages, attempting to identify who is responsible, or attending meetings arranged specifically to discuss the claim). The article then offers guidelines on how to establish effective internal claims management procedures. One point person within the firm should have overall responsibility for managing claims and must be able to create a budget that details how much dealing with the claim will cost and interact closely with counsel on a defense strategy.


The Sidama their neighbors call them Sidamo are one of the most populous tribes of southern Ethiopia. Their number amounts at least to three quarters of a million. Up to now very little has been published about them. Therefore this article by S. Stanley and D. Karsten, who are both professors of economics at the University of Addis Ababa is of importance. It is at the same time a welcome supplementation of a monograph on the Sidama which is at present in preparation at the Frobenius Institut and which is being written by Ad. E. Jensen and Helmut Straube. E. H.


This study investigated students' conceptual and procedural understanding of calculus within the context of an engineering mechanics course. Four traditional calculus students were compared with three students from one of the calculus reform projects, Calculus & Mathematica. Task-based interviews were conducted with each participant throughout the course of the 10-week quarter. Results from interviews show a distinct difference in approaches to solving engineering mechanics problems that involve calculus. Calculus & Mathematica stydents, who learned calculus with a conceptual emphasis, were found to be more likely to solve problems from a conceptual viewpoint than were the traditional students, who were mcre likely to focus on procedures. (Author) *********************************************************************** Reproductions supplied by EDRS are the best that can be made from the original document. *********************************************************************** How Students Use Their Knowledge of Calculus in an Engineering Mechanics Course Cheryl Stitt Roddick A Paper Presented at the Seventeenth Annual Meeting for the Psychology of Mathematics Education (North American Chapter)


Background: Carvacrol (CAR), a monoterpenic phenol that occurs in many essential oils of the family Labiatae including Origanum , Satureja , Thymbra , Thymus , and Corydothymus species, possess a wide variety of pharmacological properties including antioxidant and anti-inflammatory potential. This present study was designed to investigate the cardiac protective effect of CAR on diabetic cardiomyopathy in STZ-induced type 1 diabetic mice and explore its potential molecular mechanism. Methods: Type 1 diabetes was induced by the intraperitoneal injection of streptozocin (STZ) to male mice at dose of 45 mg/kg body weight (BW). The diabetic animals were divided into three groups containing eight in each: Group I diabetes, Group II and II injected with CAR at 10 and 20 mg/kg BW respectively once daily for 6 weeks. Age matched male C57 mice were used as normal controls. The plasma concentrations of glucose, total cholesterol (TC) and triglycerides (TG) levels were enzymatically determined using commercial kits. The cardiac function was measured by echocardiography. Protein levels of p-PDK1/t-PDK1, p-AKT/t-AKT, p-GSKα/β/t-GSKα/β were detected by Western blotting. Results: STZ-induced C57BL/6J diabetic mice showed an elevation in serum glucose, TG and TC level. Compared to diabetic mice, administration of CAR resulted in significant decrease ( P Conclusion: Carvacrol has antidiabetic property and can be potentially used to prevent hyperglycemia and diabetic cardiomyopathy.


Abstract : A rotating-beam fatigue machine was modified to study the thermal fatigue resistance of high temperature alloys used for turbine blades. Changes in the gas temperature of an operating turbine for a 60 min period are given; the test was designed to simulate the temperature and stress conditions as closely as possible. Schematic diagrams show the operating portions of the machine and the electric circuitry for regulating temperature and stress during the test. (Author)


The purpose of the study was to research clinical features and level of suicide risk among persons who had suicide attempts through poisoning. There were 102 patients who participated in a study. The control group consisted of 35 patients who had injured themselves with a sharp objects. As a separate group, 43 patients were examined by the Columbia-Suicide Severity Rating Scale (C-SSRS) and by the Screening Questionnaire of Moscow Research Institute of Psychiatry. Among patients who attempted suicide through poisoning were often diagnosed with an adjustment disorder (49.0%) and mental disorders due to alcohol use (37.2%). There was a smaller proportion of patients with paranoid schizophrenia (7,8%) and depressive disorders (5,9%). Retrospective study of period before suicide revealed that among 43 patients examined by the Screening Questionnaire of Moscow Research Institute of Psychiatry, there were found symptoms of affective spectrum disorders which occurred at least once during a month before suicide attempt through poisoning. With the help of the Columbia-Suicide Severity Rating Scale (C-SSRS), it was possible to assess the severity of suicide and determine the level of suicide risk.


PURPOSE: A method of cleaning a chamber equipment for fabricating a semiconductor device is to prevent a particle such as a polymer of alumina from falling and attaching on a semiconductor substrate. CONSTITUTION: A method of cleaning a chamber equipment for fabricating a semiconductor device comprises the steps of introducing a semiconductor substrate into a processing chamber and coupling a ceramic dome to the processing chamber and then performing an etching process, depositing a polymer produced in the etching process, and cleaning the polymer from a surface of the dome. In the method, the cleaning process comprises steps of separating the dome from the processing chamber, and removing the deposited polymer from the surface of the dome using a chemical polishing technology. The chemical polishing technology comprises a step of removing the polymer using a polishing solution including an acid solution.


Kinetic and equilibrium measurements were carried out for the complexation reaction of nickel(II) malonate and nickel(II) tartronate in an aqueous solution at 20 °C and at pressures up to 100 MPa. The reaction volume, ΔV0, and the activation volume, ΔVf*, for the complex formation were estimated from the pressure dependence of the stability constant and the rate constant. The results are as follows: ΔV0=13.5±1.0 cm3 mol−1 and ΔVf*=14.7±0.5 cm3 mol−1 for nickel(II) malonate, and ΔV0=13.3±0.7 cm3 mol−1 and ΔVf*=15.2±0.5 cm3 mol−1 for nickel(II) tartronate. The larger ΔV0 value compared with those obtained for dicarboxylate ligands which form a monodentate complex coincides with that malonate and tartronate form a chelate complex with nickel(II) in an aqueous solution. By appropriately estimating the volume changes associated with the outer-sphere complex formation and first-bond formation, the overall volume profile for the complexation reaction was obtained. A Similar feature regarding the volume profile f...


The problem of the consolidation of an aerated fine powder under gravity is considered. The industrial relevance of the problem is discussed and a mathematical model is introduced. The mathematical structure is that of a coupled system for three unknowns, pressure, stress, and height of the powder in the (axisymmetric) bunker containing it. The system itself consists of a parabolic PDE, an ODE, and an integral equation determining a free boundary corresponding to the height of the powder. Existence and uniqueness of a solution is established. A numerical method based on a formulation of the semidiscretized problem as an index 1 DAE is proposed and implemented. The feasibility of the approach is illustrated by computational results.


The invention discloses pomegranate rind nature dye preparation and an application of a pomegranate rind nature dye in a fabric. The preparation comprises: cleaning pomegranate rind, carrying out air drying, carrying out mechanical crushing, adding to 10 times of an aqueous solution to soak, adding sodium carbonate after the pomegranate rind is completely moistened, adjusting the pH value of the solution to 9, heating to a temperature of 95-100 DEG C, carrying out thermal insulation for 60 min, and filtering; extracting the filter residue by using a sodium carbonate-containing solution with a pH value of 9, filtering, and mixing the two extraction solutions to obtain a nature dye raw liquid; and carrying out concentration, curing and crushing to obtain the powder nature dye. According to the present invention, the pomegranate rind nature dye adopts a post-mordanting dyeing method, and provides good dyeing effects for polyamide fiber fabrics and silk fabrics; the nature dye is extracted from the waste pomegranate rind, such that characteristics of rich resources, simple preparation process and no environmental pollution are provided; the dyed fabric wears safe, and unsafe reactions caused by the synthesized dye during the use process can be not induced; and the fabric has natural fragrance, good compatibility with the ecology environment is provided, and broad market prospects are provided.


Abstract : Studies were carried out to investigate the radiation response of neural precursor cells in vitro and in vivo, to determine the role of reactive oxygen species (ROS) in the reactions of those cells, and to determine if antioxidant treatment could modify those responses. Our data show that proliferating precursor cells and their progeny are extremely sensitive to low/moderate x-ray doses (2-10 Gy), and that ROS play a major role in the sensitivity on these cells and may act in concert with p53 and cell cycledependent processes. In addition, conditions of reduced cell density, such as that seen after radiation exposure of the dentate subgranular zone, are associated with increased ROS, which may stimulate proliferation in surviving cells. Modulating ROS using antioxidant compounds may provide a means to control proliferation in damaged cells allowing for repair and recovery after radiation injury. We have begun to address specific mechanistic factors that are not only associated with oxidative processes, but that may provide additional targets for interventional treatment. The ability to ameliorate the radiation effects on neural precursor cells may provide a potential protective strategy for individuals exposed to unplanned exposure to low/moderate doses of irradiation.


The American Board of Pediatrics (ABP) has approved the Academy as a "portfolio sponsor" for Parts 2 and 4 activities of the Maintenance of Certification (MOC) program. As an AAP member benefit, no fee will be charged for the application process to obtain MOC credit.

MOC Part 2 relates to


In this paper, the frequency distribution of DBH and DBH of masson pine and oak trees in mixed forest was simulated by using normal distribution, and the relationship between DBH and tree height was fitted by 11 common curve models. The power model can well simulate the relationship between DBH and tree height.


We calculate the harmonic-gauge even l=1 mode of the linear metric perturbation (MP) produced by a particle in a weak-field circular orbit around a Schwarzschild black hole (BH). We focus on the Newtonian limit, i.e. the limit in which the mass M of the central BH approaches zero (while fixing the orbital radius and the small-object mass), and obtain explicit expressions for the MP in this limit. We find that the MP are anomalous in this limit, namely, they do not approach their standard, Coulomb-like, flat-space values. Instead, the MP grows on approaching the BH, and this growth becomes worse as M decreases. This anomalous behavior leads to some pathologies which we briefly discuss. We also derive here the next-order correction (in the orbital frequency $\Omega $) to the MP.


The significance of methodological individualism (MI) in social science is one of the most classical issues in the philosophy of social science and. Nowadays it is customary to set in opposition to methodological holism, although this expression (introduced by Watkins, 1957 is much less common than "holism," which might be much more appropriate. This has replaced the notion of "collectivism," which was sometimes used in the middle of the twentieth century (O'Neill, 1973); but this notion was still much more misleading. Not only did it carry a possible political meaning but also because political concerns were really core elements of certain viewpoints (notably Hayek, 1988; Popper, 1945), despite there being no logical link between the epistemological and the political issues. I shall, however, leave aside here this political dimension. I claim that what is at stake, generally speaking, when one speaks of "holism" is a complex and confused intuition that might not still have been completely exhausted by advocates of analytic methods, more than a specific methodology, but such that its specificity is constantly reduced as analytic methods are becoming more and more integrative.Certain important issues are currently tackled without specific reference to the notion of holism (a fortiori collectivism), such as many debates on collective behavior, collective action, collective agency, collective intentionality, etc. However the main issues are basically the same: to what extent is collective action proper understood not only (that means: is not reducible to) a mere sum of individual actions? And how can collective action properly understood result or emerge from these individual actions? In this specific context, discussions are focused just on action and the dynamic aspects of social life more than discussions about holism are (those notably include an analysis of collective beliefs not specifically oriented towards action). In other words, the question is to know whether there is an ontological specificity of a certain kind of collective action compared to individual action, such that its account would require a proper concept: the concept of collective agency


During cold rolled production of steel,each change of rolls causes a halt in production and affects the roll's grinding maintenance and consumption. Consequently,rolls are very critical to the costs of steel production.Besides the rolling accidents,surface quality problems,including inhomogeneous wear and a decrease of the surface roughness of the rolls are other main reasons for outage and a change of the rolls. Therefore,safe rolls,with superior wear resistance and roughness retentivity will be a future trend in the cold rolling steel industry. In this study,the property characteristics and in-service performance of high-speed steel( HSS) cold rolling work rolls at Baosteel are discussed. The results of this study indicate that in-service performance of HSS cold work rolls has an improvement over conventional rolls. Implementation of HSS work rolls will prolong the rolling campaign and improve the rolling stability,thus,the cost of cold rolling production can be better controlled.


1. Preface 2. About the editor and contributors 3. 1. Introduction: The language of memory (by Amberber, Mengistu) 4. 2. Is "remember" a universal human concept? "Memory" and culture (by Wierzbicka, Anna) 5. 3. Language, memory, and concepts of memory: Semantic diversity and scientific psychology (by Sutton, John) 6. 4. Standing up your mind: Remembering in Dalabon (by Evans, Nicholas) 7. 5. The conceptualisation of remembering and forgetting in Russian (by Zalizniak, Anna A.) 8. 6. A "lexicographic portrait" of forgetting (by Goddard, Cliff) 9. 7. 'Memorisation', learning and cultural cognition: The notion of bei ('auditory memorisation') in the written Chinese tradition (by Ye, Zhengdao) 10. 8. A corpus-based analysis of German (sich) erinnern (by Schalley, Andrea C.) 11. 9. "Do you remember where you put the key?": The Korean model of remembering (by Yoon, Kyung-Joo) 12. 10. The language of memory in East Cree (by Junker, Marie-Odile) 13. 11. Remember, remind, and forget in Amharic (by Amberber, Mengistu) 14. Author index 15. Language index 16. Subject index


Human pose and shape recovery is an important task in computer vision and real-world understanding. Current works are tackled due to the lack of 3D annotations for whole body shapes. We find that part segmentation is a very efficient 2D annotation in 3D human body recovery. It not only indicates the location of each part but also contains 3D information through occlusions from the shape of parts, as indicated in Figure 1. To better utilize 3D information contained in part segmentation, we propose a part-level differentiable renderer which model occlusion between parts explicitly. It enhances the performance in both learning-based and optimization-based methods. To further improve the efficiency of the task, we propose a light-weight body model called EllipBody, which uses ellipsoids to indicate each body part. Together with SMPL, the relationship between forward time, performance and number of faces in body models are analyzed. A small number of faces is chosen for achieving good performance and efficiency at the same time. Extensive experiments show that our methods achieve the state-of-the-art results on Human3.6M and LSP dataset for 3D pose estimation and part segmentation.


Nursing home administrators must be concerned with energy costs when facing the problem of rising health care costs and the desire for cost containment. Administrators should establish energy management programs to help decrease health costs and optimize energy resources.


Background and purpose: Presence of heavy metals in the environment could constitute a hazard to food security and public health. These can be accumulated in aquatic animals such as fish, therefore, this study was conducted to investigate the As, Hg, Zn, Pb, Cd and Cu concentrations in muscle tissue of Cyprinus carpio in Taham Dam Lake in 2013. Material and Methods: Twenty five fish samples were randomly collected from Taham Dam Lake. After acid digestion, As, Zn, Pb, Cd and Cu concentrations were determined by ICP-OES and Hg concentration was determined by direct mercury analyzer. Data was analyzed using SPSS. Results: The results showed that mean concentrations of As, Hg, Zn, Pb, Cd and Cu in muscle tissue samples were 17.0±5.0, 26.0±4.0, 42.0±6.0, 5.0±1.0, 8.0±2.0, and 4.0±1.0 ng/g (wet weight), respectively. The mean concentrations of metals were significantly lower than permissible limits recommended by FAO/WHO (P<0.05). Conclusion: Although concentrations of studied heavy metals is lower than standard levels but mismanagement of water resources of the Taham Dam Lake could pollute the environment and increase the heavy metals accumulation in fish tissue, thereby endangering the health of consumers.


In this paper, alternative descriptions of functions are demonstrated with the use of a computer. If we understand functions as mono-unary algebraic functions or functional graphs, it is possible, even at the school level, to suitably present many of their characteristics. First, we describe cyclic graphs of constant and linear functions, which are a part of the upper-secondary level educational curriculum. Students are usually surprised by the unexpected characteristics of such simple functions which cannot be revealed using the traditional Cartesian graphing. The next part of the paper deals with the characteristics of functional graphs of quadratic functions, which play an important role in school mathematics and in applications, for instance, in the description of non-linear processes. We show that their description is much more complicated. In contrast to functional graphs of linear functions, it is necessary to use computers. Students can find space for their own individual exploration to reveal lines of interesting characteristics of quadratic functions, which give students a new view on this part of school mathematics.


Background: Nickel stannate nanocomposites could be useful for removing organic and toxic water pollutants, such as methyl orange (MO). Aim: The synthesis of a nickel oxide–tin oxide nanocomposite (NiO-SnO2 NC) via a facile and economically viable approach using a leaf extract from Ficus elastica for the photocatalytic degradation of MO. Methods: The phase composition, crystallinity, and purity were examined by X-ray diffraction (XRD). The particles' morphology was studied using scanning electron microscopy (SEM). The elemental analysis and colored mapping were carried out via energy dispersive X-ray (EDX). The functional groups were identified by Fourier transform infrared spectroscopy (FTIR). UV–visible diffuse reflectance spectroscopy (UV–vis DRS) was used to study the optical properties such as the absorption edges and energy band gap, an important feature of semiconductors to determine photocatalytic applications. The photocatalytic activity of the NiO-SnO2 NC was evaluated by monitoring the degradation of MO in aqueous solution under irradiation with full light spectrum. The effects of calcination temperature, pH, initial MO concentration, and catalyst dose were all assessed to understand and optimize the physicochemical and photocatalytic properties of NiO-SnO2 NC. Results: NiO-SnO2 NC was successfully synthesized via a biological route using F. elastica leaf extract. XRD showed rhombohedral NiO and tetragonal SnO2 nanostructures and the amorphous nature of NiO-SnO2 NC. Its degree of crystallinity, crystallite size, and stability increased with increased calcination temperature. SEM depicted significant morphological changes with elevating calcination temperatures, which are attributed to the phase conversion from amorphous to crystalline. The elemental analysis and colored mapping show the formation of highly pure NiO-SnO2 NC. FTIR revealed a decrease in OH, and the ratio of oxygen vacancies at the surface of the NC can be explained by a loss of its hydrophilicity at increased temperatures. All the NC samples displayed significant absorption in the visible region, and a blue shift is seen and the energy band gap decreases when increasing the calcination temperatures due to the dehydration and formation of compacted large particles. NiO-SnO2 NC degrades MO, and the photocatalytic performance decreased with increasing calcination temperature due to an increase in the crystallite size of the NC. The optimal conditions for the efficient NC-mediated photocatalysis of MO are 100 °C, 20 mg catalyst, 50 ppm MO, and pH 6. Conclusions: The auspicious performance of the NiO-SnO2 NCs may open a new avenue for the development of semiconducting p–n heterojunction catalysts as promising structures for removing undesirable organic pollutants from the environment.


Using the hard-core boson approach, we study the pump-probe spectrum of molecular assemblies carrying Frenkel excitons of arbitrary structure and dimension. We present a rigorous justification of the hard-core boson approach by using the Agranovich–Toshich transformation from paulions to bosons. The resulting two-exciton Green function is used to derive a general expression of the assembly's pump–probe spectrum. We show that this expression considerably simplifies for ordered systems occupying a lattice, where we allow for the occurrence of more than one equivalent molecule in the unit cell (Davydov components). Explicit semianalytical expressions are given for the pump–probe spectrum of linear chains with alternating dipoles, ring aggregates, chains with a herringbone structure, and monolayers. In the analysis of these expressions, we focus on the overall shape of the spectrum and on the effects of probe polarization. It is shown that relaxation during the pump–probe delay time may drastically affect the pump–probe spectrum.


As the economy is developing quickly in China, and the standard of living is improving, tourism becomes a hot topic. In the first " Golden Tourism Project" , tourists have pushed forward each key scenic spot in China. Facing the increasingly igneous holiday tourism, many experts are worried about the environmental protection of the scenic spots. Based on this background, this paper demonstrates the exploitation and protection of Tourism in Xiamen City, and then draws some conclusions .


The implementation of the INSPIRE Directive in Europe and similar efforts around the globe to develop spatial data infrastructures and global systems of systems have been focusing largely on the adoption of agreed technologies, standards, and specifications to meet the (systems) interoperability challenge. Addressing the key scientific challenges of humanity in the 21 century requires however a much increased multi-disciplinary effort, which in turn makes more complex demands on the type of systems and arrangements needed to support it. This paper analyses the challenges for multi-disciplinary interoperability using the experience of the EuroGEOSS research project (www.eurogeoss.eu). It argues that multi-disciplinarity requires mutual understanding of requirements, methods, theoretical underpinning and tacit knowledge. For this purpose it is necessary to move from a focus on data discovery and access, to one that puts emphasis on the way in which different disciplines frame a problem and use data and analytical models and processes to find one or more possible solutions. In other words, we need to elicit and document analytical models, and make reference to their theoretical bases, so that researchers from different disciplines can have a bridge to understand and collaborate meaningfully across the disciplinary divide. In the EuroGEOSS project we have implemented this extension to traditional SDIs in three ways: • Firstly by adding a new brokering layer in the Service Oriented Architecture of the infrastructure in order to mediate among the multiple standards and practices adopted by different communities of science (i.e. we build bridges to them, rather than asking them to adopt our standards and protocols). Currently supported protocols include OGC, THREDDS, OpenSearch, Degree, CDI, and GBIF discovery and access REST-Full services among others. • Secondly, we have added a Semantic Augmentation Component which links to multiple vocabularies organised in Simple Knowledge Organisation System (SKOS) through a dedicated vocabulary service. This work is in collaboration with colleagues at JRC working on the INSPIRE Themes Implementing Rules, and those working in the GENESIS research project and allows users to expand their searches with semantically related concepts either within the same discipline or from other disciplines. This is very important in the context of multi-disciplinarity as each discipline tends to use specialised vocabularies and classifications. • Thirdly, we have elicited the analytical models used in the three thematic areas addressed by the project (forestry, drought, biodiversity) and expressed them through a formal notation (Business Process Modelling Notation) with a view to arrive at executing these processes through services or chains of services. 1 European Commission Joint Research Centre 2 Italian National Research Council 3 Univesity Jaume I, Castellon EnviroInfo 2011: Innovations in Sharing Environmental Observations and Information Copyright 2011 Shaker Verlag Aachen, ISBN: 978-3-8440-0451-9


Magnetic susceptibility and proton nuclear magnetic resonance ( 1 H-NMR) measurements were performed for the quasi-two-dimensional π - d interacting system λ -(BEDT-STF) 2 FeCl 4 at ambient pressure. Magnetic susceptibility arising from the 3 d spins of the FeCl 4 anion show an anisotropy at low temperature and its temperature dependence for the external field parallel to the c axis is described as a broad peak structure at 8 K. A sharp peak in the temperature dependence of T − 1 1 associated with the antiferromagnetic (AF) transition is observed at T AF = 16 K, together with the drastic splitting of the NMR spectrum below T AF . The relation between the static susceptibility and the splitting of the NMR shift suggests the existence of the relatively strong d - d AF interaction. These results can be explained by the model considering the AF-coupled d -spin system in the AF long-range-ordered π -spin system. We find that the AF phases in λ -type salts can be universally explained by this model.


Background The chronic pain and functional limitations in osteoarthritis (OA) patients can increase risk of psychiatric disorders, e.g., major depression disorder (MDD), which may further aggravate the clinical symptoms of OA. Early detection of MDD is essential in the clinical practice of OA. Materials and methods Two hundred and fifteen participants with knee OA were recruited, including 134 MDD patients (i.e., MDD group) and 81 ones without MDD (i.e., control group). Among them, 81 OA participants in the control group received a 3-year follow-up and were divided into trans-MDD group (who transforming into MDD; N = 39) and non-MDD group (who keeping non-MDD; N = 42) at the end of the follow-up. The 17-item Hamilton Depression Scale (HAMD-17), Self-Rating Depression Scale (SDS), and Visual Analogue Scale (VAS) were performed. Furthermore, serum levels of brain-derived neurotrophic factor (BDNF), vascular endothelial growth factor (VEGF), S100B, and IGF-1 were detected. Results (1) Compared with OA participants without MDD, there were significant decrease in serum BDNF and significant increase in serum VEGF and S100B and VAS scores in OA participants with MDD. (2) A mediation of the association was found between the VAS scores and the HAMD-17 scores through the BDNF as mediator in OA participants with MDD. (3) Significantly lower baseline BDNF levels and higher baseline S100B levels were detected in OA participants who transforming to MDD after a 3-year follow-up when compared with those who keeping non-MDD. (4) In the trans-MDD group, significant associations of the change of serum BDNF levels with rate of change of HAMD-17 scores were found, and baseline serum S100B levels positively correlated with the HAMD-17 scores at the end of the follow-up. (5) In OA participants, the composite indicator of BDNF, VEGF, and S100B differentiated MDD patients from controls with the area under the curve (AUC) value of 0.806, and the combined indicator of baseline BDNF and S100B distinguished trans-MDD participants from non-MDD ones with an AUC value of 0.806. Conclusion Serum BDNF, VEGF, and S100B may be potential biomarkers to identify MDD in OA patients. Meanwhile, serum BDNF and S100B shows great potential to predict the risk of MDD for OA.


The paper studies "le" in Chinese from the angle of cognitive typology on the basis of the past studies.It holds that Chinese is a language which takes bounded change between the process and the result of the action as the core and a language which places emphasis on changing and unchanging.It is different between English and Japanese in which the process of the action is the core.


The present invention discloses a fault tolerant modular switching flux linear motor and a control method of a permanent magnet, wherein the motor comprises a primary and a secondary gear teeth, the teeth are made of primary and secondary structure of the salient poles of the primary teeth comprising a permanent magnet, an armature winding and a fault-tolerant "Ш" shaped magnetic module, "Ш" shaped magnetic module includes a fault-tolerant magnetic permeability and core teeth, placed side by side transverse magnetic permeability core, the core permeability fault-tolerant features teeth, a permanent magnet alternating tangential magnetizing a permanent magnet is embedded in each piece between two adjacent "Ш" shaped magnetic modules, each phase of the armature windings of the concentrated winding, each phase armature winding groove disposed "Ш" shaped magnetic modules and traversing the permanent magnets each phase armature winding is wound about the teeth and primary armature winding of each phase is provided between the fault tolerant spaced teeth. And proposed a fault-tolerant control strategy includes fault-tolerant control method and fault-tolerant topology. The present invention has a simple structure, high power, low cost and trouble-free operation with a strong ability.


Product quality and process productivity are one of the major indicators to evaluate the performance of any manufacturing process. The quality of any product covers its appearance, geometric and dimensional accuracy, and surface finish and integrity that majorly include microstructure, micro-hardness type of parameters. Whereas, the productivity can be determined using material removal rate. Laser beam cutting is an important advanced machining process and has been scarcely explored for miniature gears. This paper reports, the effect of laser beam cutting parameters on one of the quality parameters i.e. dimensional deviation of miniature spur gears of stainless steel and material removal rate. Box Behnken design of experiments methodology has been adopted to conduct a total of twenty nine experiments where four important laser parameters i.e. power, cutting speed, focal position, and gas pressure have been varied at three levels each. The manufactured external spur gear of stainless steel consists of ten teeth, 0.750 module, 9.04 mm outside diameter, and 4.5 mm face width or thickness. The investigation found that cutting speed significantly affected material removal rate and laser power affected dimensional deviation. Individual effects of laser parameters on both material removal rate and dimensional deviation are discussed in detail in the chapter. The investigation identifies laser beam cutting as a viable substitute of conventional manufacturing processes for fabrication of quality miniature gears with high productivity.


Increased migration is, in many ways, the sine qua non of globalization. In this manuscript, we examine the single case of Chinese American immigration in the United States over a 150-year period to explore how race and interracial attitudes shape immigrant–host relations in very deep ways. We find remarkably little change in the valence of these conversations or even in the precise content of the depictions of Chinese Americans over time. A detailed analysis of depictions and conversations about Chinese Americans in a variety of contexts finds that European Americans in the United States often describe them as: (1) self-segregating, (2) lacking loyalty to the United States, and (3) hardworking and successful, but simultaneously lacking in "humanity." We highlight the way such depictions ignore any attention to basic facts; we use these data to discuss the ways that race and interracial interaction form the core of immigrant–host relations; and we use this case study to highlight how race shapes immigrant–host relations around the globe. A central aspect of globalization is increased movement and contact between people. Cheaper transportation, extreme economic disparities, and greater global consciousnesshaveallcontributedtoskyrocketinglevelsofmigration.Worldwide, the number of people living outside of their birth country has grown exponentially in the last several decades. The rate of growth of international migration is now 50% higher than it was in the early 1990s, and shows every sign of continuous increase (United Nations, 2009). A signature feature of globalization is a greater awareness of and contact between different peoples in the world—and increased levels of immigration are a core aspect of these processes. These increased levels


A dual‐view 3‐D display with multiple resolutions is proposed. The proposed 3‐D display consists of a 2‐D display panel and a parallax barrier. The parallax barrier can project the parallax image on the 2‐D display panel into views and form several viewing zones. By making viewing zones overlapping, the proposed 3‐D display can improve the resolution of the image in the overlapped area and provide multiple resolutions. Finally, the resolution is improved at the center area of a viewing zone, where there is high‐probability viewing position of the observers. A prototype is developed to verify the principle. The experimental results show that the proposed 3‐D display can improve resolution.


Two r X n matrices A and A' representing the same matroid M over GF(q), where q is a prime power, are projective equivalent representations of M if one can be obtained from the other by elementary row operations and column scaling. Bounds for projective inequivalence are difficult to obtain and are known for only a few special classes of matroids. In this paper we define two matrices A and A' to be geometric equivalent if, in addition to row operations and column scaling, column permutations are also allowed. We show that the number of geometric inequivalent representations is at most the number of projective inequivalent representions and we give a polynomial time algorithm for determining if two projective inequivalent representations are geometrically equivalent. Thus, from a computational perspective there is no additional cost to altering the definition of equivalence in this manner. The benefit is that it could lead to a new set of theorems for inequivalence with better bounds.


Changes in the rate of coronary venous flow through the affected area under the effect of intravenous jet injections of propranolol, 0.1 mg per 1 kg body weight, were assessed in 18 patients of the hyperkinetic central hemodynamic type during acute myocardial infarction. In the first group of patients, whose mean flow rate through the affected wall was 106.2 +/- 5.7 ml/min, the latter parameter decreased in proportion to the drop in double product. In the second group of patients, whose coronary venous flow rate was reduced (51.4 +/- 6.9 ml/min), propranolol-induced drop in the flow rate was less marked, as compared to the drop in double product. It was correlated with dramatically depressed pumping function of the heart.


Reciprocating air compressor is an important equipment of industries such as food packing plants, bottle manufacturing, glass manufacturing, and even non manufacturing systems etc. A sudden or unexpected failures of such significant components due to miscellaneous reasons affects the operating system leading to system seizure. The present article highlights the different failure modes of reciprocating compressor under varied operating conditions along with the appropriate maintenance strategies to diagnose and tackle the problems occurring very often. Condition monitoring technique is a vital step in maintaining the condition of working equipment at normalcy. It helps in detecting the premature and catastrophic failures leading to drastic productivity and system deterioration. This techniques gives sufficient time to develop a suitable maintenance program for each and every failure modes. In this work the maintenance program for reciprocating compressor has been developed keeping in view the failure modes of individual component.


ALEXANDER, Mell). Julie Dr. of direction the (Under Ages. Middle Late to Early the From Synagoga and Ecclesia of Evolution The Enemies: Mortal to Rivals Sibling CALL. MELISSA This thesis explores the evolution of Ecclesia and Synagoga from their philosophical origins in the fourth-century, up to their image as a wood-carving in the High Middle period. In doing so, its aim is to shed light on the reasons for the choice of women's bodies as symbols for Judaism and Christianity, to explore what this choice meant to Jews and Christians' views of each other, and to analyze the treatment of the pair in visual mediums. Up until now, scholars have overarchingly focused on the historical context surrounding the images, or their roles in increased hostility toward Jews on the part of Christians, from the eleventh-century onward. This has left a void in the study of the pair, as well as the study of Jewish-Christian relations. Scholarship has not been focused specifically on the usage of female forms, the characterization of the two as familial by Hildegard of Bingen in the twelfth-century, nor has it sufficiently illuminated why striking changes were made in the manner in which the two were portrayed, in a specific fifteenth-century example. Through an analysis of secondary literature and an examination of the images themselves, this thesis demonstrates that the choice of women's bodies directly reflected a Roman cultural influence on the Early Church; that ideals of motherhood, virginity, and sacred kinship held by Hildegard directly affected her vision of the pair; and transmutative gender seen in science and popular forms of entertainment in fifteenthcentury Erfurt, had a direct effect on the manner in which the Ecclesia and Synagoga were understood, evolved, characterized, and depicted. This examination of the two symbols suggests that they occupied a complex, didactic, evolving space in Christian culture throughout the Middle Ages, and that the gendering of the two played a notable role in how Jews and Christians viewed each other. Therefore, the complexities of the choice of women as representative, and the evolving nature of the images themselves, ought to be more carefully studied and dissected.


On the basis of the Overhauser (1971) and Axe (1980) treatment of Debye-Waller factors in incommensurate systems, a calculation allows the authors to determine the temperature range Delta T on which the phase is floating in modulated structures. Their estimations are in good agreement with experimental results obtained by Blinc et al. (1983) in Rb2ZnBr4 from NMR measurements ( Delta T approximately=10K) and by Emery et al. (1983) in ThBr4 from EPR measurements ( Delta T approximately=2.6K).


Scholars have often identified the Greek polis, and Athenian democracy in particular, as the first example of majority rule. This chapter reviews the evidence for Greek deliberative procedures and reassesses how much they conformed to majority rule, and how much they made use of consensus‐deliberation, understood through engagement with current work on deliberative democracy. It discusses the evidence of Hellenistic decrees from the Greek poleis for which we have voting figures, to show that what we find is for the most part unanimity or near‐unanimity. It then discusses the Athenian evidence to reassess whether the deliberative system in Athens practiced strict majority rule, or left space for considerable consensus seeking and even unanimity. It argues that consensus‐ based forms of deliberation were a key element of Greek decision making, which secured the cohesion of Greek communities as well as the synthesis of wide‐spread knowledge.


This short academic note explores media interpretations of a recent interim order of the National Green Tribunal in India, in light of legal rights of residents and prevailing doctrines of legitimate expectation and promissory estoppel. The note then concludes with suggestions for obtaining clarifications on the subject for maintaining harmony in interpretation of the Tribunal's interim orders with these extant legal rights and doctrinal assumptions.


Every industry has utilized machines of various types for many functions. The manufacturing industry has utilized machines since the industrial revolution for mass manufacturing. Operating machines continuously can lead to faults and require maintenance and repairs. As computing power increased and various technologies such as embedded systems, artificial intelligence, deep learning, cloud computing etc. were developed, new systems were implemented to perform diagnostics on machines. In this paper, A conceptual system architecture of a cloud based AI system to predict potential failure of a component by analyzing data collected from various sources and develop inspection and maintenance schedules is proposed. The application of technologies such as Artificial Intelligence, Cloud computing and process mining in the system is discussed in detail. The operation of the system in a real world condition is discussed by developing a system architecture for maintenance and failure prediction of aircraft fan blades of an aircraft engine. The future application of the system with potential increase in capability is discussed.


Objective: Rumen is rich source of  anaerobic microbes and these microbes has ability to produce  bacteriocin  like substances ,The present study was aimed at Partial Purification of bacteriocin like substance from Rumen Liquor obtained from the slaughtered cattle. Methods:  Rumen liquor samples were collected from slaughtered cattle   of fifteen samples collected the anti- microbial activity was seen only in those animals which were fed just before slaughter.  The samples were precipitated by 60percent ammonium sulphate saturation these precipitates were further purified using ion-exchange chromatography (SP-Sepharose) and eluted with 1.0 M sodium chloride as a single peak. The purity of protein was confirmed by SDS-PAGE analysis. Results: Antimicrobial activity was obsereved in at 60percent ammonium sulphate saturation and these The protein with anti-microbial activity was eluted with 1.0 M sodium chloride as a single peak using ion exchange chromatography, molecular size  of these protein was around 6.5kDa, . Further the purified protein was subjected for in gel tryptic digestion and nano LC-MS analysis of the peptides released followed by the identification of protein using MASCOT analysis which had shown similarity with the fimbrial protein of Pseudomonas aeruginosa ( SO4440 ) and oligopeptide ABC transporter, ATP binding protein ( B72300 ) ) [23] . Bacteriocin (BViA) falls within the superfamily of ABC transporters and ATP binding proteins demonstrate highest homology matches with the BViA. Conclusion: Thus the observations made in this study clearly demonstrate that the peptide purified from rumen liquor was indeed bacteriocin like substance.  KEY WORDS: Rumen liquor, anti-microbial activity, purification, protein analysis


Network processors(NP) has the advantage of reducing time-to-market and supporting design reuse,and also has the ability of dynamic adding new function or design.In order to improve the programmability of network processors,Network(processors) can be designed with soft-core processors,such as soft-core Nios Ⅱ in Altera FPGA.This paper firstly introduces the architecture of Nios Ⅱ and its custom instruction.And then it gives the architecture of forwarding software in Nios Ⅱ-based(network) processors.Finally,it shows a design method of IPv4 packet forwarding software for Nios Ⅱ-based network processors.


Lambda DNA (λ-DNA) molecules were labeled with SYBR Gold nucleic acid stain using a PDMS-based programmable microfluidic chip (Automaton). Single DNA molecules were detected in a vertically integrated liquid-core waveguide chip.


The estimation of soil organic carbon storage is very important to the research of carbon cycle.The soil organic carbon density and storage of Chongqing karst area was estimated,using the data of 1412 soil profile from the second soil survey of China and formulating fertilization for soil conditions in 2007.Integrating the soil map,land use status quo map and district map of Chongqing karst area,the index of soil organic abundance were introduced and the characteristic of soil organic distribution in different soil and landscapes were analyzed.Results showed:the storage of soil organic carbon of Chongqing karst area to the depths of 20 cm and 100 cm were 1.43×1011 kg and 3.29×1011 kg,respectively.Carbon density of 20 cm soil was 1.26-7.20 kg m-2,and carbon density of 100 cm soil was 1.43-25.72 kg m-2.The amount of soil organic carbon varied significantly at different soils and landscapes,the index of soil organic abundance of soils and landscapes at 20 cm depth ranged from 0.73-1.74 and 0.39-1.20,and that at 100 cm depth changed between 0.32-3.00 and 0.46-1.70,respectively.The soil organic carbon storage of unit area at 20 cm depth was above the average level of China,but that at 100 cm depth was below the average level of China in Chongqing karst area.In a word,the soil organic carbon storage was relatively indigent in Chongqing karst area.


. Amphibians are harvested for various purposes around Mount Manengouba including food, international pet trade and cultural reasons. At least seven frog species are regularly collected and consumed: Conraua crassipes, C. goliath, C. robusta, Trichobatrachus robustus, Astylosternus spp., Xenopus amieti, Kassina decorata . Over-exploitation of C. robusta for food and T. robustus for the international pet trade, in addition to the harvest of tadpoles for human consumption, is currently increasing and expected to have negative eff ects on wild populations. Th e males of the Hairy Frog, T. robustus , locally known as "Ebod" are viewed upon by locals as being mystical. It is believed that these frogs fall from the sky, and that childless human couples can turn fertile aft er having eaten this frog. All interviewed locals declared to have once eaten a frog, while only 70% of them knew about the cultural signifi cance of the Hairy Frog. Collection of any frog species is undertaken all year round but peaks in the dry seasons (both for food and pet trade). Prices for two large or three medium-sized individuals of C. robusta are US 2 at the local food markets, while pairs of the Hairy Frogs are sold for US 8 to the international pet trade. We discuss the need to set up plans for the sustainable harvest to maintain viable populations of these species in the region.


In 2010, quantum anomalous Hall effect (QAHE) in graphene was proposed in the presence of Rashba spin-orbit coupling and ferromagnetic exchange field. After a decade's experimental exploration, the anomalous Hall conductance can only reach about 0.25 in the units of $2e^2/h$, which was attributed to the tiny Rashba spin-orbit coupling. Here, we theoretically show that Re-intercalation in graphene/CrI$_3$ heterostructure can not only induce sizeable Rashba spin-orbit coupling ($>$ 40~meV), but also open up large band gaps at valleys $K$ (22.2 meV) and $K' $ (30.3 meV), and a global band gap over 5.5 meV (19.5 meV with random Re distribution) hosting QAHE. A low-energy continuum model is constructed to explain the underlying physical mechanism. We find that Rashba spin-orbit coupling is robust against external stress whereas a tensile strain can increase the global bulk gap. Furthermore, we also show that Re-intercalated graphene with hexagonal boron-nitride can also realize QAHE with bulk gap over 40~meV, indicating the tunability of $5d$-intercalated graphene-based heterostructure. Our finding makes a great leap towards the experimental realization of graphene-based QAHE, and will definitely accelerate the practical application of graphene-based low-power electronics.


The wavelet packet energy spectrum analysis method of magnetic memory signals was proposed.On the theoretical basis of wavelet packet transform,by carrying out stretching experiments on specimens of 45 steel and aeronautical ferromagnetic material 18CrNi4A,magnetic memory signals under different loads on the surface of the specimens were acquired and analysed with wavelet packet energy spectrum.Thus the stress concentration area and its extent of the specimens could be judged effectively.


The present invention is a land (portion between the groove) for recording information and a groove (groove), the constituent conventional concentric tracks if the record or reproduce continuous data relates to an optical disk and an optical disk drive apparatus using this optical disk has a track the stop is 1, and the rotation required for each run a track jump also spiral track configuration, recording at the time of the jump, and to solve the problem that the recording rate is decreased rapidly as a result of this jump, the physical formed onto the surface of the disc groove and has the lands between the grooves, and the information recording track comprises a number of track sectors that form the information recording units, respectively, in the disk radial direction so as to display the rotation management information of the sector management information and the disc such as the address of each track sector Words and a groove wobbling, bridge so as not to overlap in the wobbling portion of the disk radial grooves adjacent to each other The at least one pair of the wobble ring, and unloading the wobble ring) were placed in a configuration of providing each one rotation. With this arrangement, it is not necessary to provide the address of the foot only can be improved even data and light efficiency, it is possible to increase the recording density by using both the lands and grooves.


As technology becomes more embedded in our daily lives, there is a great deal of hope about the use of information technology to achieve positive community outcomes like increasing access to local information, promoting civic engagement, and creating avenues for collaboration and communication. While these technologies provide opportunities for community groups to achieve their own goals, most community computing studies describe community members in fairly passive ways as users of existing systems rather than as meaningful contributors to the design process. The Civic Nexus project is a three year participatory design project that involves working with community groups to increase their capacity to solve local community problems through the use of leading edge computing tools. Our view of participatory design is one in which community members take control of the design process in terms of both directing what should be done and maintaining the technology infrastructure. In this paper, we describe our process of participatory design with three community groups and present associated challenges for designers engaging in participatory design in community computing contexts.


Hemoglobinopathies are the most common type of inherited disease in human. in India the most frequent and clinically significant hemoglobin structural variants are HbS, HbD and HbE. The HbS mutation, in which a glutamic acid at position 6 in the β chain is substituted for valine Sickle cell disease is a major health problem in some parts of India. 2 ml blood sample was collected from 350 anemia patient and PCR-RFLP method was used for hemoglobin S analysis. Out of 350 samples, in four individuals, HbS mutation was found in homozygous (β 6/β 6) condition. All four individuals are Sickle cell cases. In conclusion, the percentage of Sickle cell disease was observed as 1.14% in Eastern UP anemic patients.


This study examines the association between temporary employment incidence and wage inequality by focusing on the asymmetric distribution of temporary employment across different wage layers, speci...


Peoples sense on noise lies not only on the sound level but also on the frequencies of sound wave. It is significant to study the spectrum of impact noise and the relation between spectrum of impact noise and transient time length. The impact noise is analyzed in theory and a test in the paper, and an effective measure reducing the impact noise is proposed.


On the situation of the development of Shunde district,Foshan,it makes an analysis of the unharmonious things in the development of cities and villages of Shunde,puts forward the working keys at present,and points out that the fundamental strategy to solve the limited source problem is the urbanization development strategy of regional integration.


Characteristic charge-transfer absorption bands of some heterocyclic nitrones as electron donor with tetracyanoethylene, 2,3-dichloro-5,6-dicyanobenzoquinone and chloranil as electron acceptor have been measured in methylene chloride solution. The stoichiometry, apparent formation constants and transition energies of the charge-transfer complexes formed as well as the effect of solvent and the stability of these complexes are discussed.ZusammenfassungDie charakteristischen Charge-Transfer Absorptionen einiger heterocyclischer Nitrone als Elektron-Donor mit Tetracyanoethylen, 2,3-Dichlor-5,6-dicyanobenzochinon bzw. Chloranil als Elektron-Acceptor wurden in Methylenchlorid als Lösungsmittel gemessen. Stöchiometrie, effektive Bildungskonstanten und Einfluß des Lösungsmittels auf die Stabilität der Komplexe werden diskutiert.


This study examined a research model developed to understand work satisfaction and emotional and physical well-being of teachers. Data were collected from 833 school-based educators using questionnaires completed anonymously. Five groups of predictor variables identified in previous research were considered: individual demographic and situational variables, work stressors, role conflict, social support and components of psychological burnout. Some support for the model was found. Individual demographic characteristics, work stressors and components of psychological burnout were strong predictors of work attitudes and emotional and physical health. Social support had little effect on these dependent variables.


A review of recent studies of X‐ray scattering from films of semiconducting polymers is presented with an emphasis on materials used for thin film transistors. Common types of scattering experiments are described with a focus on synchrotron X‐ray sources. The basic molecular packing structure and microstructural features of polycrystalline thin films of polythiophenes and polyfluorenes are described. The influence of processing conditions, such as thermal annealing, on the microstructure of these materials is outlined and example studies on polythiophenes are presented in detail. The microstructures of blends of these polymers and their co‐polymers are also discussed