Objective To construct a lentiviral targeting SATB1 gene and provide the basis for further experiments in vivo and in vitro.Methods SATB1 gene targeting short hairpin RNA(shRNA) was cloned into lentiviral expression vector pGCSIL-GFP.The recombined vector pGCSIL-GFP-shSATB1 confirmed by PCR and sequencing was cotransfected with the pGCSIL-GFP-shSATB1 packaging plasmids mixture into 293T cells by Lipofectamine2000.Virus in the supernatant was collected and the virustiter was measured.Results PCR and DNA sequencing demonstrated that the inserted sequences were correct.The titer of virus was 2×107 pfu/ml.Conclusion The lentivirus RNAi vector targeting SATB1 has been successfully constructed.


Motherwort exhibits a curative effect on kidney damage and its component, ajugol, also might improve kidney damage. Therefore, this study assesses the mechanism whereby ajugol alleviates renal injury in multiple myeloma. After establishment of animal model of multiple myeloma (n
 = 30), mice received treatment with low-dose and high-dose ajugol (n = 10, each group). And 10 healthy mice were taken as control group and 10 modeled mice were untreated (model group). Following treatment, the serum and spinal cord samples of the mice were collected, in which the levels
 of Cys-C, RBP, Cr, UN, CD4+, CD8+, and CD25+ were examined and the expression of LILRB4 and PFKFB3 proteins in myeloma tissue were detected. Compared with model group, the levels of serum Cys-c, RBP, Cr and UN in low-dose and high-dose groups decreased, but
 were still higher than those in control group (P <0.05). Of ajugol groups, the levels in high-dose group were lower (P <0.05). Importantly, the treatment of ajugol greatly alleviated lesions of myeloma tissue and reduced infiltration of inflammatory cells via lowering the
 levels of serum CD4+, CD8+, and CD25+. Besides, ajugol dose-dependently decreased LILRB4 and PFKFB3 expression in myeloma tissue samples. Ajugol, a bioactive component of motherwort, blocked the LILRB4 signaling and reduced PFKFB3 expression to inhibit the
 activity of immune cells and thereby alleviating renal injury in multiple myeloma. This is related to significant inhibition of multiple myeloma cell glycolysis and reduction of intracellular energy metabolism, indicating the anti-cancer potential of ajugol.


Design and create functional applications that interact with remote data sources. You get a thorough introduction to the latest Flash Builder tools learning how you can use the built-in wizards, MXML or pure ActionScript 3 to build information-rich applications for the browser or AIR applications. Hand's on tutorials guide you through each iteration including building user interaction, charting, incorporating audio and video, customizing the UI; and a code repository provides re-usable code that you can modify and deploy in your own applications. *Hand's on approach with projects and code provided *Color illustrations, tips and tricks deliver nuanced interface solutions *Code repository provided for re-use in personal projects


a sharply demarcated lesion characterized by hyperkeratosis with broad low papillomatosis and acanthosis, overlying laminated hyperkeratosis, and slight increase in basal melanin pigment (Fig. 1c). A diagnosis of segmental seborrheic keratosis-like keratinocyte epidermal nevus (SSKKEN) was made. Both epidermal nevi (EN) and ordinary seborrheic keratosis (SK) can present in linear or segmental distribution. Segmental SKs should be distinguished from linear SKs, with the latter characterized by multiple linear, spindleor leaf-shaped eruptions that distribute linearly or radially in the direction of skin cleavage lines. SK following Blaschko's lines were reported by Mabuchi et al., who suggested that this phenomenon can reflect a genetic mosaicism. The occurrence of SSKKEN has been previously rarely described. Akasaka et al first described similar cases of agminate keratinocyte EN arranged on Blaschko's lines resembling multiple segmented SK. According to the authors, segmental SK may be a possible variant of keratinocyte EN developed after birth along the Blaschko's lines, since in both type of lesions, the same genetic mutation may be present (in particular, of FGFR3 and PIK3CA). The most important differential diagnosis of SSKKEN is with nevus agminatus, which clinically may resemble the keratinocyte epidermal nevus, but dermoscopic findings show the typical melanocytic pattern, absent in EN and in SK. The recognition of these lesions is important also for a most appropriate therapeutic management since a laser therapy may be a good option for treatment rather than surgical management.


The ten articles in this issue represent emergent areas of scholarship as well as fascinating new approaches to familiar subjects of study. They explore contemporary and historical dynamics in diverse national contexts, including Mozambique, Zambia, Zimbabwe and South Africa, with some studies traversing transnational boundaries through innovative lenses trained on regional peace-building efforts, natural resource sharing and water governance, international migrant labour and the production and consumption of news media. The articles in this issue also represent, in true JSAS fashion, a wide array of scholarly disciplines, covering history, anthropology, urban planning, politics, media and development studies, while also introducing innovative and sometimes interdisciplinary methodological approaches. The studies cluster around four thematic areas. The first theme explores the character of upwardly mobile expressions of post-colonial urbanisms in southern Africa and the socio-political developments underpinning them. The second considers new theoretical and methodological approaches to struggle historiography. The articles in the third thematic cluster offer critical analyses of the labour market and the processes and consequences of extractive labour recruitment and employment in three paradigmatic sectors – the mining industry, public health and domestic service. The final theme concerns the transboundary mechanisms involved in, and regional stakeholders' perceptions of, powerand resource-sharing processes. Julie Archambault's rich ethnographic study of the global 'fitness revolution' in Maputo begins the first thematic cluster. Her account explores the rise in recent years of sites and temporal 'regimes' of fitness, which have physically reconfigured the urban landscape and reflect potentially new forms of self-fashioning at work in this post-colonial city. These spatialised 'enclaves' of fitness offer the opportunity for (mostly young) Mozambicans not only to mould their bodies through a disciplined and communally sanctioned repertoire of exercises but also to participate in a highly aspirational project of self-improvement. Although the ways in which fitness enthusiasts discursively framed their hoped-for transformation suggest the influence of recent globalised and neo-liberal markers of progress, as Archambault convincingly argues, the present-day valorisation of particular forms and expressions of 'body work' needs to be historically situated in Mozambique's colonial and socialist past. For example, the project of socialist modernisation embarked on by the ruling Frelimo party entailed the adoption of particular forms of body work and the evocation of a specific ethical 'register' predicated on discipline, self-criticism and an explicitly ever-continuing struggle. Archambault sees the persistence of this socialist register in the future-embracing discursive orientation of her informants and in the timescales and rhythms created through the everyday practice of fitness in Maputo. The following article, by Vanessa Melo and Paul Jenkins, retains the readers' gaze on aspirational politics in contemporary Maputo while providing a valuable and differently spatialised urban planning perspective. Their study examines urban development in the


Abstract This article explores the reflections of Caribbean culture found in mid-century calypso album cover art. Calypso cover art offers important documentations of Caribbean folk life and cultural identity pre-independence, but at the same time, facilitate the exportation of colonial fantasies about local life to attract tourists. The images examined invariably construct Caribbean islands as "places to play" (Sheller, 2003) and its people as carefree and even childish natives. We use semiotics and critical visual analysis to analyze mid-century record album cover characterizations of the primordial rhythm of folk life and caricatures of native culture, as well as the ways touristic esthetics adapted Calypso, including the figure of the Coconut Woman, as a soundtrack for colonial fantasies and fuel for the colonial gaze. This article reveals how minor, even peripheral, objects such as Calypso records promoted as fun and festive consumer goods reveal powerful, yet relatively unnoticed, insights into visual communication.


Southwest Indian Ocean (SWIO) represents a noteworthy region to study green turtle Chelonia mydas spatial ecology. Indeed, spatial complexity of the region and presence of numerous nesting sites (mostly islands) as well as vast nesting areas (mostly East-Africa and Madagascar) is a unique opportunity to understand the role of space in turtle ecology. For more than twenty years now, a number of effective studies have been conducted locally in major areas. Due to recent progress in wildlife tracking, movements of marine turtles between those sites are starting to be well-documented. Here, we propose an original approach to integrate this knowledge using a spatially explicit individual-based model.


Summary Cytogenetic studies were carried out on Rhamdella microcephala collected from the headwaters of the Machado river, a tributary of the Sapucai river, Minas Gerais, Brazil. Sixteen specimens exhibited 2n556 chromosomes, with 18 metacentrics, 30 submetacentrics and 8 subtelocentric-acrocentrics (FN584). The nucleolar organizing regions (NORs) were identified in the interstitial position on the long arm of a submetacentric pair (pair 12). Chromomycin A3 staining evidenced only the NOR-bearing segments. Positive C-band segments were identified in a pericentromeric position in most of the chromosomes and the NOR-bearing segments were also C-band positive. Some aspects related to the chromosomal characteristics of Rhamdella microcephala are discussed.


The presence of acute kidney injury in the setting of acute heart failure (AHF) or acute decompensated heart failure (ADHF) is very common occurrence and was termed cardiorenal syndrome 1 (CRS1). Neutrophil gelatinase-associated lipocalin (NGAL) in the blood and urine is one of the earliest biomarkers of acute kidney injury due to ischemia or renal toxicity. Cystatin C is early marker of renal dysfunction. NT-proBNP is valuable in the diagnosis, prognosis and treatment of acute and chronic heart failure. This study was aimed to evaluate the diagnostic efficacy of the combination of plasma NGAL, Cystatin C and NT-proBNP in diagnosis of CRS1.

 There were 139 patients with AHF or ADHF in the department of Cardiovascular resuscitation and Interventional cardiology at Ho Chi Minh City 115 People Hospital from November 2018 to May 2019. This was a prospective cohort study.

 There were 48 cases (rate 34.5%) with CRS1, mean age 66.12±15.77, men accounted for 50.4%. There were no significant differences of vital signs on admission, diagnosis, type of heart failure between CRS1 and Non-CRS1 groups. The urea, creatinin on first day (creatininD1) and third day (creatininD3), NT-proBNP, Cystatin C, NGAL levels were higher in the group with CRS1 than Non-CRS1, the difference was statistically significant p<0.05. The optimal cut-off NGAL for diagnosing CRS1 was >353.23 ng/ml, Area Under Curve (AUC) was 0.732 (95% CI 0.65–0.80, p<0.001), sensitivity 74.47%, specificity 68.48%, positive predictive value 54.7%, negative predictive value 84%. The optimal cut-off Cystatin C for diagnosing CRS1 was >1.81 mg/dl, AUC was 0.787 (95% CI 0.71–0.85, p<0.001), sensitivity 75%, specificity 83.52%, positive predictive value 70.6%, negative predictive value 86.4%. The optimal cut-off NT-proBNP for diagnosing CRS1 was 17681 pg/ml, AUC was 0.683 (95% CI 0.59 – 0.76, p<0.001), sensitivity 53.19%, specificity 77.17%, positive predictive value 54.3%, negative predictive value 76.3%. Combined three biomarker plasma NGAL, Cystatin C and NTproBNP, the specificity of the diagnosis was the highest 95.6%, the positive predictive value was the highest 84.62% in diagnosing CRS1.

 The combined plasma NGAL, Cystatin C and NT-proBNP is high value in the diagnosis of CRS1 in patients with AHF or ADHF.

 Type of funding sources: None.


This paper begins with a review of 'Gibbard's paradox' for rights and Gibbard's proposal for avoiding the paradox. This is followed by a theorem that identifies the pairs where rights are directly relevant (at some profile) when Gibbard's proposal is adopted. As the next step, the paper reviews 'Sen's paradox' and the 'private Pareto principle'-which has recently been proposed by Hammond as a replacement for the traditional Pareto principle, with the argument that this will make rights and Paretian comparisons compatible. The remainder of the paper is devoted to an analysis of the nature of the social pairwise comparisons that the private Pareto principle recommends for the pairs of alternatives where rights are directly relevant (at some profile). This analysis reveals that, on these pairs, the private Pareto principle makes two important concessions to rights.


Talent is the "first resource" for state-owned enterprises to achieve high-quality development. Only by following the law of market economy can we realize the optimal allocation of talent elements and play the maximum value. The government has repeatedly stressed that it should not only introduce local talents from regions, but also seek all development talents, use good talents without sticking to one pattern, and gather talents from all over the world. The construction of market-oriented selection and employment mechanism is an important measure to implement the reform of state-owned enterprises. It is of great significance to improving the market-oriented operation mechanism of SOEs, stimulating the development vitality and endogenous impetus of SOEs, and promoting the high-quality development of SOEs. From the perspective of internal and external reform and development situation, this paper analyses the new requirements and challenges of the reform of state-owned enterprises and the market-oriented selection and employment of power grid business, and further clarifies the direction and policy requirements of the construction of the market-oriented selection and employment mechanism. The importance and necessity to promote market-oriented selection and employment mechanism are comprehensively and systematically expounded.


The optimization of the epitaxial quality and ordering of coaxial GaN/InGaN/GaN nanoheterostructures is the main focus of this study. Two approaches for the realization of upright ZnO nanipillars, used as templates for the epitaxially grown GaN layers, with their respective degrees of pattern arrangement are introduced. Consequently, the growth of coaxial GaN/InGaN/GaN quantum wells (for three different samples) along with the corresponding structural and optical properties is investigated. By comparing the optimized InGaN quantum well growth conditions in two different MOCVD reactors, we could reduce the FWHM of an intense room temperature photoluminescence peak of the InGaN quantum well at 3 eV from 300meV to 190meV. Cathodoluminescence mapping along the nanotubes revealed two main peaks that are emerging from the sides and top facets of the tubes backing an argument for different respective In incorporation.


In this paper laser-induced modification of photosensitive glass-ceramic materials under YAG:Nd second harmonic picosecond pulses is observed. The method for such modification based on laser processing and subsequent heat treatment is developed. The comparison for infrared femtosecond modification is introduced.


Our field and subsurface studies of glacial strata from construction sites and borings indicate that the glacial history of the New York City area is complex. The Ronkonkoma and Harbor Hill terminal moraines are evidence that the area has experienced more than one glacial advance. There is more to the story, however, than simply ice advance, retreat, repeat. Many locations in New York City display seemingly simple stratigraphy, such as thick layers of till over bedrock or 100' of outwash sands. Most sites aren't as obviously complex as one offering multiple tills intercalated with outwash and varved strata. When characteristics other than soil type are taken into consideration, however, stratigraphic differences sometimes appear. A change in color or mineralogy, for instance, might indicate ice coming from another direction. A change in engineering properties can also contribute to the art of unraveling glacial history.


The subject of the research is the category of transcendental consciousness in N.A. Berdyaev's philosophy, which appears as an alternative to the classically oriented epistemological consciousness. Comparing the concept of mind, developed by the Russian philosopher, with the phenomenological approach to the issue in the Western European tradition, the author examines the reasons for which Berdyaev considers it necessary to construct such a consciousness in a subject, and comes to the conclusion that the values of transcendental consciousness are freedom, self-consciousness and the subject-subjective communication.


The present work deals with the development of a model that optimizes a supply chain of bioethanol and bio-power. The growing concern about environmental issues has led the society to seek for solutions in order to replace fossil fuels. Part of this research is focused in the transport sector since it is a major contributor to the high emission levels of greenhouse gases. To reverse the situation two hypotheses are proposed: integrate a new the type of fuel consumed in the existent vehicles or introduce new type of vehicles in the market. Regarding the first hypothesis, bioethanol is currently the most exploited proposal and it has the greatest potential for expansion. The other solution involves the development of the market for electric cars. Considering the two presented solutions, a linear programming model was implemented, based on the works of Zamboni et al. [2] and Giarola et al. [3]. The referred model is built to understand what the best economical solution to produce energy from bio-products is: production of bioethanol or bio-power generation. Bioethanol production is performed by the Dry Grain Process (DGP) technology and bio-power is generated using the gasification and combustion. Taking into account the different technologies, results are promising regarding the implementation of a biomass combustion system. In a situation to encourage clean energy production, the production of electricity using combustion is the most profitable situation, followed by the production of bioethanol by DGP and finally by gasification. Analyzing a situation of selling the electricity produced without tax benefits, indications favor the production of bioethanol.


The cellular slime mold, Polysphondylium pallidum, has two EDTA-resistant types of cell-cell adhesion. The major component of them has been identified as a glycoprotein with a molecular mass of 64 kDa on SDS-PAGE (refer-red to as gp64). We found that a substantial amount of the gp64 run as dimer, when gp64 was dissolved in SDS-sample buffer without 2-mercaptoethanol and then subjected to electrophoresis. The occurrence of a homophilic dimer was demonstrated by analyzing the dimer-like band on a gel for its amino acid sequence and amino acid composition. The dimer-like band also was analyzed by three sorts of monoclonal antibodies, two of which recognize respectively a conformational epitope and a denatured epitope of the protein moiety of gp64. The data indicate that the native conformation of gp64 is necessary for dimer formation.


Droplet impinging phenomena frequently happens in many fields such as spray cooling, coating and inkjet technology and it became origin of single droplets impingement and spray process to modify. Droplet behavior after collision is relative to droplet velocity, droplet size and other parameters. Simulation of contact angle between wall and droplet in wetting phenomena, in particular, accounts for inertia force, viscous force, gravity and surface tension. While static contact angle which is material property has influent to analyze phase interaction between gas and liquid phases, dynamic contact angle is necessary to calculate for dynamic interaction. Dynamic contact angle has various values according to capillary numbers in term of droplet velocity, viscous force and surface tension. The aim of this study is that numerical result considering dynamic contact angle is compared with the numerical data when using static contact angle and experimental data. The numerical result predicted well the deformation of droplet spreading radius and height. The numerical results considering dynamic contact angle have smaller spreading radius and higher height than the data considering static contact angle. Furthermore, the numerical result shows good agreement with experimental data in spreading diameter, height and contact angle change as time elapsed.


A new means for modeling blast effects of all types of reactants including vapor cloud explosions has been developed and verified against empirical data. Methods such as the TNT‐equivalency model are still being widely used to simulate vapor cloud explosions and blast effects. However, many limitations exist in the accuracy of those models. Use of such flawed models could potentially provide for deleterious results from an explosion such as loss of property and/or life as well as the ramifications of liability. This should be of extreme interest to not only the chemical process industry, but also to insurerers who must understand the nature of the risk that is being under written, government safety compliance organizations and the legal profession which must either defend or litigate liability cases resulting from explosions.


Abstract Hexamethylene bis(N-methylimidazolium) bis(dichloroiodate) (HMBMIBDCI), an ionic liquid iodinating reagent, have been prepared and characterized. Its ability to perform iodination reactions with a variety of substrates has been explored. In general, iodination reactions of aromatic and heteroaromatic amines proceed with good yields in the absence of solvent. Reactions of terminal alkynes in the presence of 1,8-diazabicyclo [5.4.O] undec-7-ene and tetrahydrofuran have been investigated as well. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications® for the following free supplemental resource: Full experimental and spectral details.] GRAPHICAL ABSTRACT


Abstract Background C. difficile recurs when dormant spores germinate in the dysbiotic gut, facilitated by an increase of 1° vs. 2° bile acids. SER-109, an ecology of bacterial spores purified from stool of healthy donors, is an investigational first-in-class microbiome therapeutic intended to facilitate microbiome restoration and reduce risk of recurrent C. difficile (rCDI). Rapid engraftment of spore-forming species is associated with (i) higher doses of SER-109 in our dose-ranging Phase 1b study (Ph1b) and (ii) reduced rCDI in our Phase 2 trial (Ph2). We explored whether higher doses of SER-109 were associated with an increase in 2° bile acids. Methods Whole metagenomic shotgun (WMS) data were generated from stool, and species were identified using a proprietary build of MetaPhlAn. Evaluation of spore-forming species richness and bile acid concentrations identified effects of SER-109 treatment. A triple stage bioreactor model of the human gut and rCDI was used to evaluate the impact of microbial therapeutics. Results Ph1b subjects who received a higher dose (>1.5 × 108 SporQ) had significantly higher spore-forming species richness than subjects who received a low dose (<1.5 × 108 SporQ) at Week 1 post-treatment (P = 0.017, Figure 1). Spore-forming species richness in patients receiving a low dose in Ph1b was comparable to that observed in non-recurrent patients in Ph2, who received the same mean dose (Figure 1). Ph1b subjects in the high dose group had a significantly higher concentration of 2° bile acids as compared with Ph1b low dose subjects and non-recurrent Ph2 subjects (P = 0.036, P < 0.001, respectively, Figure 2). A higher dose (3 × 108 SporQ × 3 days) suppressed recurrence in a gut model of rCDI; a single dose did not. Conclusion Higher doses of SER-109 are significantly associated with (i) higher spore-forming species richness, (ii) concentrations of secondary bile acids, and (iii) prevention of recurrence in an gut model of CDI. These results suggest that SER-109 in the Phase 2 trial was biologically active and catalyzed a functional change in the microbiome of a subset of subjects; a dose increase may optimize efficacy across a broad population. Seres has initiated a Phase 3 study of SER-109 to reduce rCDI, which includes an increase in dose titer and frequency. Figure 1: Figure 2: Disclosures M. Henn, Seres Therapeutics, Inc.: Employee and Shareholder, Salary. C. Ford, Seres Therapeutics, Inc.: Employee and Shareholder, Salary. E. O'Brien, Seres: Employee and Shareholder, Salary. J. Wortman, Seres Therapeutics, Inc.: Employee and Shareholder, Salary. L. Diao, Seres Therapeutics, Inc.: Employee and Shareholder, Salary. C. Desjardins, Seres Therapeutics, Inc.: Employee and Shareholder, Salary. A. Tomlinson, Seres Therapeutics, Inc.: Employee and Shareholder, Salary. K. Litcofsky, Seres Therapeutics, Inc.: Employee and Shareholder, Salary. M. Wilcox, Seres Therapeutics, Inc.: Consultant, Research Contractor, Scientific Advisor and Shareholder, Research support. A. Buckley, Seres Therapeutics, Inc.: Research Contractor, Research support. P. Bernardo, Seres Therapeutics, Inc.: Employee and Shareholder, Salary. B. McGovern, Seres Therapeutics, Inc.: Employee and Shareholder, Salary. J. G. Aunins, Seres Therapeutics, Inc.: Employee and Shareholder, Salary. D. N. Cook, Seres Therapeutics, Inc.: Employee and Shareholder, Salary. M. Trucksis, Seres Therapeutics, Inc.: Employee and Shareholder, Salary.


One of the main ideas of agile development is to perform continuous integration, in order to detect and resolve conflicts among several modular units of a system as soon as possible. Whereas this feature is well catered for at the level of programming source code, the support available in formal specification environments is still rather unsatisfactory: it is possible to analyze the composition of several modular units automatically, but no assistance is given to help modify them in case of problems. Instead, the stakeholders who build the specifications are forced to attempt manual changes until reaching the desired functionality, in a process that is far from being intuitive. In response to that, this paper presents procedures and algorithms that automate the whole process of doing integration analyses and generating revisions to solve the diagnosed problems. These mechanisms serve to complete an agile specification environment presented in a previous paper, which was designed around the principle of facilitating the creative efforts of the stakeholders.


To study the effects of different protein resources on protein and energy deposition,one hundred and eighty 14-day old broilers were randomly divided into three groups with 6 replications.Three kinds of purified diets of which protein were FAA,oligopeptide and casein respectively were fed.The results showed that 1) the energy deposition of feather,carcass and whole body were 0.083 MJ/kg,0.075 MJ/kg and 0.095 MJ/kg(P0.05);0.55 MJ/kg,0.71 MJ/kg and 0.94 MJ/kg(P0.05);0.65 MJ/kg,0.78 MJ/kg and 1.03 MJ/kg(P0.05),respectively;2) the protein deposition of feather,carcass and whole body were 2.75 g,2.87 g and 4.08 g(P0.05);15.01 g, 18.25 g and 20.08 g(P0.05);17.75 g,21.12 g and 24.16 g(P0.05),respectively;3) compared with FAA group,the ALT and AST level in serum of oligopeptide and casein group increased while the UA content decreased(P0.05).


A textbook of bacteriology: the application of bacteriology... , A textbook of bacteriology: the application of bacteriology... , مرکز فناوری اطلاعات و اطلاع رسانی کشاورزی


The established mechanism for infection of most cells with adenovirus serotype 5 (Ad5) involves fiber capsid protein binding to coxsackievirus-adenovirus receptor (CAR) at the cell surface, followed by penton base capsid protein binding to (cid:1) v integrins, which triggers clathrin-mediated endocytosis of the virus. Here we determined the identity of the capsid proteins responsible for mediating Ad5 entry into the acinar epithelial cells of the lacrimal gland. Ad5 transduction of primary rabbit lacrimal acinar cells was inhibited by excess Ad5 fiber or knob (terminal region of the fiber) but not excess penton base. Investigation of the interactions of recombinant Ad5 penton base, fiber, and knob with lacrimal acini revealed that the penton base capsid protein remained surface associated, while the knob domain of the fiber capsid protein was rapidly internalized. Introduction of rabbit CAR-specific small interfering RNA (siRNA) into lacrimal acini under conditions that reduced intra- cellular CAR mRNA significantly inhibited Ad5 transduction, in contrast to a control (nonspecific) siRNA. Preincubation of Ad5 with excess heparin or pretreatment of acini with a heparinase cocktail each inhibited Ad5 transduction by a separate and apparently additive mechanism. Functional and imaging studies revealed that Ad5, fiber, and knob, but not penton base, stimulated macropinocytosis in acini and that inhibition of macropinocytosis significantly reduced Ad5 transduction of acini. However, inhibition of macropinocytosis did not reduce Ad5 uptake. We propose that internalization of Ad5 into lacrimal acini is through a novel fiber-dependent mechanism that includes CAR and heparan sulfate glycosaminoglycans and that the subse-quent intracellular trafficking of Ad5 is enhanced by fiber-induced macropinocytosis. (cid:6) g/ml) 0.2 mg/ml trypsin-EDTA at 4°C for 1 h (23). The were lysed in radioimmunoprecipitation (RIPA) buffer by 15 passages through a 23-gauge syringe needle followed by two freeze-thaw cycles. The lysate was centrifuged for 5 min at 3,000 rpm in an Eppendorf 5415C centrifuge at 4°C, and the supernatant was collected. The cell lysates (150 (cid:6) g) were blotted with appropriate primary antibodies (rabbit polyclonal anti-Ad5 antibody for penton detection and mouse monoclonal anti-GFP antibody for GFP-knob detection) and IRDye 800-conjugated secondary antibodies. A similar protocol was used to evaluate Ad5 uptake (15 PFU/cell) in LGAC pretreated with either 500 (cid:6) M EIPA or 10 (cid:6) M Lat B at 37°C for 1 h relative to that for LGAC pretreated with vehicle (DMSO); fiber protein internalization in cell lysates was tracked using the mouse monoclonal anti-fiber protein antibody for fiber detection in combination with an appropriate IRDye 800-conjugated secondary antibody. Cell infection assays. Relative transduction efficiencies for rabbit LGAC, Caco-2, and HeLa cells were determined by adding Ad-GFP at an MOI of 5 or 10 PFU/cell, incubating the cells fo r 1 h at 4°Cbefore washing them, and then incubating the cells for 10 to 12 h at 37°C. GFP positivity was deter- mined by flow cytometry as previously described (50). To compare the abilities of individual viral components to block Ad5 transduction of LGAC and HeLa cells, the cells were preincubated with various doses of recombinant penton, fiber, knob, or the penton-blocking peptides RGD and LDV in binding buffer for 2 h at 4°C.


The RNPLS&T's www-site ecological section (since 2003) is oriented toward library users and partner libraries working for ecological education and ecological awareness building. It provides access to bibliographic annotated database "Ecology: Science and Technology", e-library in ecology, publishes monthly bibliographies of new acquisitions and videos of thematic webinars. All these resources are used to inform user and partners on publications in ecology and sustainable development and on RNPLS&T activities in ecological education and awareness building. The section popularity and traffic rate enables to conclude on its relevance and effectiveness. The authors offer the results of the bibliometrical analysis of the ecological section materials and analyze statistical metrics such as number of accesses, views, scroll reach, access duration, key phrases of search queries when moving to the RNPLS&T www-site within the period from January 1, 2011, to December 31, 2917. Based on the data obtained, the vectors of the site section improvement are defined. The study makes the first stage of bibliometrical studies of RNPLS&T's www-site ecological section.


When attaining puberty, I tried to hide that I was an Ainu by removing the hair on my hands and feet—'hairiness' is a feature said to be representative of the Ainu. I often heard negative ideas about the Ainu: the Ainu language has no written form; the Ainu have no sense of propriety; the Ainu are inferior to the ethnic Japanese. I am of mixed Japanese and Ainu background, but I had been troubled by my blood relationship with the Ainu for a long time. One day, I realised that the Ainu have inhabited this land, which is called Hokkaidō at present, since time immemorial, and that our ancestors handed down their wisdom for living in harsh winters, for example, how to make their houses, instruments of everyday life and clothing. This realisation connected me later with my job at the Hokkaidō Center for Ainu People. The Ainu Association of Hokkaidō is entrusted with the management of the centre by the Hokkaidō Government, and provides information on the history and culture of Ainu people for visitors. Before describing how I have revitalised Ainu embroidery (see Figure 11), I want to record some memories of my family.


Colposcopy may be defined as stereo scopic examination of the cervix under direct illumination. The usual magnifica tion is about X 10 although enlargement to X 270 (colpomicroscopy) has been de scribed. The ectocervix has received most attention by colposcopy, but the lower third of the endocervix, the vaginal epi thelium, and the vulva, have also been studied by this method. The findings of colposcopy depend in the main upon three characteristics of the cervicalportio:epithelial configuration and architecture, epithelial thickness, and blood-vessel arrangement. The prime aim of colposcopy is to detect not only the preulcerative and preproliferative stages of invasive cancer but also the early atyp ical changes that may progress to car cinoma. The instrumentis binocularwith a built-in light source. The headpiece is on an adjustable stand with a transformer in the base. Our own instrument, made by Moeller of Hamburg-Wedel, is similar to the one used by Hinselmann today. It magnifies ten or twenty times, The dis tance from the terminal lens to the object inspected is 22 cm. A built-in Leica at tachment facilitates taking 35-mm. color


While the Community Treaties provided the institutional framework for the European Community, much of what now makes up the constitution of the European Union was not provided for in those Treaties, but evolved within that framework. This is certainly true of the role of national parliaments. There is nothing about the role of national parliaments in any of the Treaties concluded prior to the Maastricht Treaty, and even then the references appear not in the body of the Treaty, but only in two Declarations annexed to it, one on the role of national parliaments in the European Union and the other on the Conference of the Parliaments. While the former states that it is important to encourage greater involvement of national parliaments in the activities of the European Union, it gives no indication of what that involvement should be. The Treaty of Amsterdam goes a step further. It includes a protocol on the role of national parliaments. This is important in that, for the first time, it gives substantive treaty recognition to their involvement in European Union activities. But, while it is markedly more supportive than the Maastricht Declarations, it does not confer any specific powers on national parliaments, nor does it attempt to define their functions.


In this demonstration, paper is burned in a closed container containing sufficient oxygen to consume all the paper by the reaction (C6H10O5)n + 6nO2 ---> 6nCO2 + 5nH2O.Paradoxically, the flame expires while half of the paper remains. This demonstrates that thermodynamics or stoichiometry is insufficient to explain everyday chemical processes, and that kinetics is often necessary. The gases in the container are analyzed by GC before and after combustion, and the results are examined in detail.


Four-hundred-and seventy-three Hansen's disease patients who had no disabilities when diagnosed were re-evaluated in an attempt to determine the incidence of disabilities, during the first few years of chemotherapy. The World Health Organization classification of disabilities in Hansen's disease patients using five grades was our standard. Our physiotherapist carefully examined each patient for motor and for sensory dysfunction of the eyes, hands and feet at the time of diagnosis and at the time of re-evaluation. Three patients were found to have developed disabilities developed within two months after chemotherapy was started. One of these two had neuritis at the time of diagnosis and the commencement of chemotherapy. The third patient developed disabilities after five years of irregular chemotherapy. It was concluded that disability occurs very infrequently (in less than 1 percent of patients) in Hansen's disease after the commencement of chemotherapy (AU)


Since Carbon Nanotubes (CNT) were discovered in the early 90's a whole new research field have evolved. CNTs have many properties that make them desirable for nano-scale electronics. One area that is receiving increasing attention is the nano-scale thin films. Recently, graphene has been suggested as a thin film candidate for nano-electronics. Our work is focusing on other techniques to realize thin films of CNTs using bacteria. In this work we describe a technique to purify and segregate CNTs from the iron impurities to use the CNTs for thin films. After much research into a proper and repeatable cleaning process we have developed a new method of using bacteria to remove impurities from CNT's. Our methods specifically apply to CNTs obtained by the use of HiPCo method of manufacturing the CNTs. However, we think the method can be extended to other cases. We expect this approach will lead to finding novel conductors, structures and thin films for future nano-engineered devices that could be investigated further for use in nano-scale electronics, implants and bio-materials.


While several studies have found that prescribing practices do not conform to chronic obstructive pulmonary disease (COPD) treatment guidelines, none have examined longitudinal patterns of use of long‐acting beta2‐agonist (LABA) and long‐acting muscarinic antagonist (LAMA) therapy across an entire country. We undertook a nationwide follow‐up study to describe treatment patterns in new users of long‐acting bronchodilators.


One of the key concepts in studying the changing nature of the roles of parents, governors and teachers is that of involvement (Everard and Morris, 1985). It is the changing levels of involvement of these three groups, one with another, in pursuit ofa more effective and responsive school, that causes the traditional roles to be brought . into question and to change. This gradual, incremental change is often imperceptible, particularly to people closely involved with a school, yet some landmarks exist for all three groups as they have striven to respond to the changing educational circum-


Introduction: Research has linked an altered gut microbiome to symptoms of irritable bowel syndrome (IBS). In constipation-predominant IBS (IBS-C), methane production appears important as methane levels on breath are proportional to the degree of constipation, and antibiotic elimination of methane signifi cantly improves constipation. Th e predominant methane-producing organism in humans is Methanobrevibacter smithii. Recent data suggests certain HMG-CoA reductase inhibitors (statins) may reduce methane production by inhibiting methanogenesis. Th is study examined the eff ects of various statins on methane production in fresh human stool homogenates. Methods: Five female subjects recruited based on high breath methane production (average=69.6ppm) provided a total of 8 fresh stool samples each. Samples were homogenized in 1XPBS (2g stool/3ml PBS) in an anaerobic chamber at 37°C and divided into 5 stoppered fl asks. To assess statin eff ects, head gas withdrawn through a stopcock was collected at baseline, then every 30min for a total of 270min, and analyzed on a Quintron Model SC gas chromatograph for methane levels. Nine statins were initially assessed for methane inhibition at a concentration of 5mg/g stool: lovastatin lactone and hydroxyacid, pravastatin lactone and hydroxyacid, simvastatin lactone, mevastatin lactone, rosuvastatin lactone, and atorvastatin lactone and hydroxyacid. Once the ideal statin was determined, the eff ects of concentrations of 0.04, 0.12, 0.48, 1, 5, and 10mg/g stool were tested by sampling head gas every 90min aft er statin addition, up to 720min.Further assessments were then performed comparing three forms of lovastatin (lactone, diol and hydroxyacid). Results: Lovastatin lactone was identifi ed as the only eff ective methane inhibitor (Figure 1), signifi cantly inhibiting methane levels by -65% of the control stool. Lovastatin lactone at 5mg/g produced the maximum inhibiting eff ect resulting in an average methane level of 3% of the control over time (Figure 2). In a fi nal validation comparison of 3 forms of lovastatin (5mg/g), both the lactone and diol forms proved to be eff ective. In all assessments, hydroxyacid forms were least able to inhibit methane production in fresh stool samples. Conclusion: Lovastatin lactone and lovastatin diol at concentrations of 5mg/g stool signifi cantly reduce methane production in human stool homogenates. Future studies are needed to assess the eff ect of this statin on methane production and IBS-C symptoms in humans. 1772


This article will analyze Ethiopia's multi-faceted relations with the countries and ideologies which constitute her main regional-strategic context. These are the countries of the Red Sea, the Nile basin and the worlds beyond them. Ethiopian attitudes toward Islam and toward modern Arab nationalism is an important subject because of its profound importance for both an understanding of crucial past developments as well as for preparing for future eventualities. So too are basic Middle Eastern attitudes toward Ethiopia: What do the Muslims of the Middle East fundamentalists, radicals, moderates think of Ethiopia? How do Arab (or pan-Arab) nationalists conceive her? What are the approaches to Ethiopia stemming from the values of modern territorial-Egyptian nationalism? What are the deeper considerations behind the policies of other Middle Eastern states, movements and organizations? Are these all monolithic? And do different Middle-Eastern identities predetermine diverse basic concepts of that so-closely relevant yet somewhat mysterious neighbor Ethiopia. In studying these questions I followed 20th century Arabic literature and printed journalism that refer to and discuss Ethiopia. Dozens of books and thousands of articles and editorials were written on this sub-


Mesoscopic Materials: Mesoscopic Particles Embedded in Matrix and some Porous Materials Reaction and Coated Materials * Clusters: Properties in Vacuum Properties Held on Surfaces.


This study surveys the literature regarding the motivations that are behind lying behavior, mo rality of lying behavior, and identifies two different types of lying behavior. This literature review also observeslie detections that can be used to identify destructive and typical dishonesty. Lying behavior is categorized into two groups: those who lie to benefit themselves (pro-self), and those who lie to benefit others (pro-social). This study will analyze each category and distinguish the differences between them in regards to identification, mot ivations, and detections. In addition, this study will also cover the morality of ly ing behavior as recognized through previous research.


economies with G F majorized correspondences are established under noncompact setting of G convex spaces. These theorems improve, unify and generalize many important known results in recent literature.


A long-standing problem in avalanche science is to model the formation and propagation of ice- dust clouds that accompany fast moving dry snow flowing avalanches. Since the winter of 2002/2003 photo- grammetric measurements of snow avalanche clouds have been performed at the Vallee de la Sionne test site. Synchronized images acquired from two different viewing angles allow the construction of three-dimensional powder cloud surface models. Between 2003 and 2006 seven avalanches with initiation volumes over 50'000 m 3 were recorded. Plume heights reached over 100 m and the avalanches entrained up to 10 million m 3 of air. Using high resolution laser scans of the terrain it was possible to investigate the formation and development of the pow- der clouds as a function of terrain and avalanche speed, thereby gaining valuable information concerning the flow dynamics. The plumes form continuously at the avalanche front and then diffuse slowly. Using isolated plumes as markers, we calculate the travel distance between the point of initiation and the final suspension height. The up- ward velocity appears to be divided into a high-velocity, forced expulsion stage and a slower diffusion stage. Seg- regation effects are also visible as packets of extruded mass are thrown upwards and then descend, leaving an ice-dust suspension hanging in the air. Lateral spreading speeds are significantly slower than the front propaga- tion. Furthermore, there is also definite terrain influence as plume formation appears to be concentrated at gullies and extreme changes in slope angle.


So far, theoretical efficiency limits for the intermediate band solar cell have been calculated under the assumption that the absorptivity of the solar cell is 1 for all photon energies larger than the smallest subband gap. In the present work, efficiency limits have been calculated under the assumption that the cell is covered by spectrally selective reflectors. The efficiency limit for the 1 sun 6000 K black body spectrum is found to increase from 46.8% to 48.5% and the limit for the AM1.5G spectrum (as defined by ASTM G173–03) is found to increase from 49.4% to 52.0%.


We present the fullO(α) electroweak radiative corrections to the process e+e− → tt̄γ at the International Linear Collider (ILC). The computation is performed with the help of the GRACE-Loop system. We present the total cross-section and the top quark forward-backward asymmetry (AFB) as a function of the center-of-mass energy and compare them with the process e+e− → tt̄. We find that the value of AFB in tt̄γ production is larger than AFB in tt̄ production. It is an important result for the measurement of the top quark forward-backward asymmetry at the ILC. Applying a structure function method, we also subtract the QED correction to gain the genuine weak correction in both the α scheme and the Gμ scheme (δ Gμ W ). We obtain numerical values for δ Gμ W which are changing from 2% to −24% when we vary the center-of-mass energy from 360 GeV to 1 TeV.


Summary — Polyamide nanocomposites with different octakis(dimethylsiloxy, 3-glycidoxypropyl)octasilsesquioxanes (POSS) contents (0.5, 2, 4 wt. %) were obtained during melt blending. SEM results showed that POSS are uniformly dispersed in polyamide 6 matrix (Fig. 1). FT-IR and DSC analysis indicated that the addition of POSS promotes modifications of the polyamide crystal structure, which consist of the progressive development of crystals and significant increase in the glass transition temperature, crystallization temperature and the crystallization rate of the polyamide 6 (Figs. 2 and 3, Tab. 1). Tensile tests, performed on dried samples, revealed that strength and elongation at break were appreciably modified by the presence of POSS (Fig. 4, Tab. 2). Compared with the neat polyamide 6, the impact strength of PA 6/POSS composites is enhanced (Tab. 2). Dynamic mechanical thermal analysis (DMTA) demonstrated that both the storage modulus (G') and relaxation temperatures (T, T and T), especially glass transition temperature (T )o f the PA6/POSS composites significantly increased (Fig. 5, Tab. 3).


Abstract Background and Purpose  Altered levels of consciousness resulting from a vascular insult to the brain can vary from confusion to coma. A disruption in the function of the brain stem reticular activating system in the brain stem or both cerebral hemispheres and thalami causes coma. This study is aimed at finding the effect of transcranial direct current stimulation (tDCS) on motor recovery in altered conscious patients after traumatic brain injury and cerebrovascular accident. Materials and Methods  A total of 100 patients admitted to the neurology and neurosurgery unit of the university hospital were screened and 40 subjects who satisfied inclusion criteria were recruited and randomly divided into two groups, group A (experimental) ( n  = 20) and group B (control)(n = 20), by computerized randomization. Written informed consent was taken from all the caregivers before recruitment. After taking the preliminary assessment, anodal tDCS is given to the motor area (C3/C4 ipsilesional), sensory area (P3/P4 ipsilesional), and left dorsolateral prefrontal cortex (F3) according to the 10/20 electroencephalogram montage for two sessions of 20 min/day for 7 consecutive days. Routine physiotherapy was also given the same as group B. Results  At baseline, there were no significant group differences in the baseline characteristics. The groups passed the normality test. The results were tested for statistical significance between the groups by Mann–Whitney U test and by one-way analysis of variance and Tukey Honest Significant Difference for post-hoc comparison; the results were statistically different with p -value less than 0.05 with a large effect size. Conclusion  We conclude, based on the results of this study, that tDCS can be effective in motor recovery in altered consciousness patients. It is noninvasive, cost-effective with minimal contraindications, and does not interfere with other modalities in the intensive care unit. Hence, it can be administered safely under the supervision of a qualified therapist.


Many anomalous features of the diffusion of penetrants into polymers, around and below the glass transition, such as the occurrence of history-dependent diffusion coefficients, sigmoid and "two-stage" sorption, and time-dependent boundary conditions, can be shown by non-equilibrium thermodynamics to be consequences of a simple model of a glasslike transition. Below the transition temperature the system is viewed as undergoing a generalized relaxation with respect to certain characteristic internal variables of even tensorial rank, while above the transition temperature the system is viewed to be in internal equilibrium with respect to these variables. It is pointed out that the mechanism of Fickian diffusion above the glass transition may depend on the distribution of sizes of cavities, particularly the mean cavity volume, as well as the total free volume of the system.


Post-quantum cryptography (PQC) has drawn significant attention from various communities recently and one of the recent advances is the hardware acceleration of PQC algorithms. While Hamming Quasi-Cyclic (HQC) is one of the recently announced National Institute of Standards and Technology (NIST) fourth-round PQC standardization candidates, very few related hardware implementation works have been reported, particularly lacking solid works on important components such as the sampler. As a fixed-weight sparse vector sampler with constant-time operation is critical to the hardware HQC accelerator, in this paper, we present a novel hardware-implemented LOw-latency and ConStant-timing fixed-weight sampler (LOCS). In total, we have proposed three stages of efforts. First of all, a new algorithm for efficient realization of the fixed-weight sparse vector generation based on Fisher-Yates shuffle algorithm is proposed. Then, we have innovatively designed the algorithm into a new hardware sampler: LOCS. Finally, we have conducted a thorough comparison to showcase the efficiency of the proposed sampler, e.g., the proposed LOCS involves 66.7% less latency time than the state-of-the-art design $(n=17,669)$ while remaining constant-time operation. To the authors' best knowledge, this is the first hardware-implemented pure constant-time (no failure probability) fixed-weight sampler for HQC.


Asri Busana store in the procurement of goods based on consumer interest. Procurement can ' t run properly because the information obtained was limited to recapitulation the bill of sale, to determine consumer interest so far only based on the results recapitulation of the bill of sale to see the total units sold of each item. Resulting piled of inventory. From the problems, with the sales turnover of information systems that can be detailed by type of goods, name of goods, brand and size by using the sell-through method can help existing problems. The process of calculating the value of sales turnover of goods is by dividing the sales units with units of Goods Available for Sale . Reporting from the system are reported sales turnover of goods that can be detailed by type of goods, name of goods, brand and size. With a sales turnover information system, can help Asri Busana Stores in planning the purchase of goods.


In utero electroporation (IUE) is commonly used to study cortical development of cerebrum by downregulating or overexpressing genes of interest in neural progenitor cells (NPCs) of small mammals. However, exogenous plasmids are lost or diluted over time. Furthermore, gene knockdown based on short‐hairpin RNAs may exert nonspecific effects that lead to aberrant neuronal migration. Genomic engineering by the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR‐associated 9 (Cas9) system has great research and therapeutic potentials. Here we integrate the CRISPR/Cas9 components into the piggyBac (PB) transposon system (the CRISPR/Cas9‐PB toolkit) for cortical IUEs. The mouse Sry‐related HMG box‐2 (Sox2) gene was selected as the target for its application. Most transduced cortical NPCs were depleted of SOX2 protein as early as 3 days post‐IUE, whereas expressions of SOX1 and PAX6 remained intact. Furthermore, both the WT Cas9 and the D10A nickase mutant Cas9n showed comparable knockout efficiency. Transduced cortical cells were purified with fluorescence‐activated cell sorting, and effective gene editing at the Sox2 loci was confirmed. Thus, application of the CRISPR/Cas9‐PB toolkit in IUE is a promising strategy to study gene functions in cortical NPCs and their progeny. © 2016 Wiley Periodicals, Inc.


This study explores the political cause of social polarization and inequality increased dramatically in South Korea since the IMF crisis in 1997. It is conventionally argued that the economic recession accompanied by rising rates of unemployment and a slow down in economic growth has largely caused the growing social polarization and inequality. Contending the conventional economic explanation, this study provides an alternative explanation to emphasize a political aspect of social polarization and inequality from a theoretical view of democracy as the political condition for social integration and equality. The main point of this study is that the growing social polarization and inequality is a direct outcome of the political failure of the Korean government, not just the result of the downturn of an economic cycle. This study thus argues that the government should play its active role for solving the problem of social polarization and inequality by the expansion of the social welfare system and the reform of the big?business centered economic structure, redirecting its present economic policy priority of promoting economic liberalization towards the institutionalization of the substantial democracy.


Abstract The aim of the study is to present the link between organic farming and sustainable consumption in the light of the European Green Deal strategy (EGD). The article discusses whether the increase in the supply of organic food and the solutions proposed in the strategy will contribute to the spread of sustainable consumption. The article was prepared based on a critical analysis of the literature based on available statistical data, strategic documents, and scientific studies. The paper uses desk research and secondary data from Eurostat, FAOStat, and IFOAM for European Union countries (EU) between 2014 and 2020. It has been found that the implementation of the principles of sustainable consumption through organic farming requires action to increase consumers' confidence in organic food products. The credibility of organic farming must be built at every stage of the supply chain. From the perspective of achieving the principles of sustainable consumption and production through the development of organic farming, it is important to ensure a reliable certification system at every stage of the supply chain and labeling that takes into account detailed information about the product. Public procurement, which could generate sustainable demand for organic food products, is the development opportunity for organic farming. The analysis showed that the actions and tools identified in the European Green Deal strategy, within the framework of the three main priorities, appear to be legitimate and crucial for the development of organic agriculture and market for organic food products.

http://www.zer.waw.pl/pdf-170889-94672?filename=ORGANIC FARMING IN THE.pdf


Due to the fall in levels of rainfall as well as scarcity of water year by year in Tamil Nadu, our main aim is to reduce the natural water required for the growth of vegetable crops, using the treated sewage water. This process is done using natural materials like Tamarind Seed, Ash of the Rice Husk, Charcoal, Moringa Oleifera Seed (Drumstick Seed) and Fine Sand. For this project we have collected Sewage Water from our College Sewage Treatment Plant and we have done filtration. The filtration process is done by aeration method using fish tank motor for 20 minutes. After filtration, the water is allowed to settle down for another 20 minutes and then the water is transferred to the next filter. The same process is continued up to the last filter. In the last filter there is fine sand in the top layer and charcoal in the bottom layer. In this filter the filtration process is done by gravitational force. The natural materials were selected by studying each of their properties. The chemical properties of the treated water were analyzed for pH, Turbidity, COD and BOD. These values were compared with the values of the raw sewage water. The volumetric efficiency of the filter was also checked based on the water obtained after the treatment process. On analyzing these properties and from various studies we have found that this treated water can be used for agricultural purposes such as growing vegetable crops, nutrition crops etc. Based on our studies we have found that this water can be used for spinach, flat beans, ridged gourd, broccoli etc. Key WordsSewage Water, Vegetable Crop, Rice Husk, Charcoal, Moringa Oleifera Seed Powder, Tamarind Seed Powder INTRODUCTION: India faces major environmental challenges associated with waste generation and inadequate waste collection, transport, treatment, and disposal. Current systems in India cannot cope-up with the volumes of waste generated by an increasing urban population, this impacts on the environment and public health. The challenges and barriers are significant, but so are the opportunities. The priority is to move from reliance on waste dumps that offer no environmental protection, to waste management systems that retain useful resources within the economy. Waste segregation at source and use of specialized waste processing facilities to separate recyclable materials that plays a vital role. Based on various studies the treated water is good for vegetation purposes. The treated water is used for growing nutrition crops and vegetable crops such as flat beans, spinach, ridged gourd, peas, broccoli, and eggplant. Using the treated wastewater not only reduces the water and land pollution but also reduces the water required for growing crops up to 60%. This method of agriculture can be used when there is drought in an area as well as during summer seasons. This method can also be used for roof farming and for gardening purposes.


A field experiment was conducted to investigate the effects of different fertilization patterns on late rice nutrient uptake and distribution under rice-wheat rotation system in Nanhu district of Jiaxing city.The results showed that nitrogen was the main factor in rice production.Fertilization could promote plant for N,P,K absorption;N and P were mainly in grain,while K(86.51%~91.69%) was mainly in stalk.N distribution in the grain reduced with fertilizer application,but P and K would increase.The N and K utilization efficiency were 52.3% and 51.7%,thus the P utilization efficiency was only 6.2% in the NPK fertilizer treatment.Meanwhile,the amount of N,P and K that every 100 kg grain need were 1.67~2.31 kg,0.39~0.48 kg and 1.58~2.19 kg.


Rapid fluctuations in the amplitude and phase of radio waves propagating through the ionosphere may be caused by small-scale plasma density irregularities. Ionospheric scintillation events have been observed on signals from GPS satellites during successive phases of October 2003 storm. Those observations have been made by means of a commercial single frequency GPS receiver, suitably operated in order to carry out the measurements of those fluctuations caused by small-scale electron density irregularities. The relationship between scintillation and TEC fluctuations is also investigated by means of dual frequency data from a close geodetic receiver. Structures of enhanced electron density have been observed during occurrence of scintillation and high TEC fluctuations events. Phase scintillation is characterized by means of a recently new proposed estimator, which provides a more robust information than classical phase scintillation index against data detrending effects.


The effect of adding sodium tetraphenylborate (NaBPh 4 ) on a LCST type phase separation of a mixture of D 2 O and 3-methylpyridine is investigated by visual observation and small-angle neutron scattering (SANS). In the case that the amount of salt is smaller than 50 mM, the mixture colors below the phase separation temperature. When the amount of salt is increased, the phase separation disappears and a single peak profile is observed at finite- Q by SANS. These results indicate that a periodic structure is induced in one phase region by the addition of NaBPh 4 .


Psychology and psychiatry have grown up in relative isolation from each other. Medicine, "the mother of the sciences," was less intimately connected with the birth and early life of psychology than with the origin of most of the other sciences. The study of the mind was first undertaken in systematic form by the philosophers, and this association remained for many centuries a controlling one in the history of psychology. Even at the present day, the question whether psychology should more properly affiliate with philosophy or with the natural sciences is regarded as a fit subject for discussion, and opposing views on it are expressed by eminent psychologists. Students of other sciences are sometimes inclined to deny the right of psychology to call itself a natural science, and for two reasons. On the side of method, there is still much that is current in psychological books and discussions that appears to the student of empirical science quite strange and foreign in tone. And on the side of results, doubt is expressed whether psychology really has anything to teach, which common sense and common observation have not sufficiently acquainted us with. Psychology seems sometimes to be engaged in an "elaboration of the obvious," in stating familiar facts in obscure phraseology, or at the best in putting together familiar facts into systematic shape, without adding to the store of facts. Whatever may be the proper abstract definition of a science, in the concrete we demand that a science which we are to study shall do more than classify and label facts that we already know; we require it to teach us something new; and on the practical side we wish it to guide our action where common sense is inadequate to meet the situation. These requirements are abundantly met by the physical, the natural, and the medical sciences; in comparison with these, psychology, the


'Is this boom of [museum] construction (with the creation of new facilities, renovation and refurbishment) synonymous with architectural merit? Has quantity been accompanied by quality and more importantly, by meaning? Nothing is less certain.' This issue, according to Yves Nacher, lies at the heart of any debate on the question 'Whither museums?' The author is an architect and head of mission at the French Architectural Institute; he is chairman of the French section of the International Forum of Young Architects (IFYA).


In higher education student affairs are complicated but important.Therefore,it is currently urgent to enhance the actual effect of handling student affairs.This paper holds that handling student affairs effectively shall keep pace with the new times.Furthermore,by defining group counseling,the paper analyses the feasibility of its entrance to student affairs as a new model in the new times.


Excavators unearthed the Black Venus near the Czech village of Dolní Vestonice in 1924, on a hillside among charred, fractured mam moth bones and stone tools. (Despite its nickname, the Black Venus is actually reddish—it owes its name to the ash that covered it when it was found.) Since the mid-nineteenth century , researchers had discovered more than a dozen similar statuettes in caves and open-air sites from France to Russia. All were cradled in layers of earth littered with stone and bone weaponry , ivory jewelry, and the remains of extinct Ice Age animals. All were depicted naked or nearly so. Collectively , they came to be known as Venus figurines, after another ancient bare-breasted statue, the V nus de Milo. Guided at least in part by prevailing sexual stereotypes, experts interpreted the meaning of the figurines freely. The Ice Age camps that spawned this art, they concluded, were once the domain of hardworking male hunters and secluded, pampered women who spent their days in idleness like the harem slaves so popular in nineteenth-century art.


This article examines how New Zealand Maori have been drawn into an emerging comparative genocide debate, one where historically marginalized groups have used the Jewish Holocaust, its imagery and vocabulary as a means of articulating their own experiences of victimization, in the quest for some form of justice, restitution, and healing. I will argue that Maori activists have been strongly influenced in the recent past by North American indigenous activists (such as David Stannard and Ward Churchill), whose arguments and style have been borrowed to advance Maori interests. This follows a pattern of incorporating the protest styles and images of other marginalized groups, from North America and elsewhere. While the widespread use of "holocaust" and accusations of "holocaust" denial arguably have a role to play in the United States— where there are proven cases of genocide—the operationalization of such terminology in New Zealand (where such claims are unproven) is certainly fraught with controversy.


Respiratory distress syndrome (RDS) is a major cause of neonatal morbidity and mortality. It is primarily a disease of premature neonates. The aim of this study was to evaluate the impact of maternal betamethasone administration on the fetal pulmonary arteries (PAs) and umbilical arteries (UAs) and the correlation between RDS development and PA Doppler results.


Background:
 Approximately 3 million Americans have ill managed lipidemia due to statin intolerance (SI) or statin-associated myopathy (SAM). Atorvastatin and simvastatin are the most prescribed statins which are transported into the liver by SLCO1B1 and metabolized by cytochrome P450 (CYP) 3A4 and 3A5. CYP3A4*22 and CYP3A5*3 are two polymorphisms known to decrease their activity; thus, increasing the systemic daily exposure (AUC) and serum concentration (C
 max
 ) of unmetabolized statin. In Caucasian (CAU) populations the prevalence [5-7% CYP3A4*22 and 90% CYP3A5*3] and effect of these polymorphisms is well characterized but not in African American (AA) populations. We hypothesize that the prevalence of SI and SAM are correlated with CYP3A4/5 polymorphisms in AA populations.

 Methods:
 After IRB approval, saliva samples were collected from patients currently prescribed atorvastatin or simvastatin at The Ohio State University Medical for genotyping. SLCO1B1 status was assessed to control for its confounding effect. Participants with polymorphic results were contacted to complete 8 blood draws over 13hrs for pharmacokinetic analysis. Electronic medical records were utilized to collect demographic information, medical histories, risk factors, and concomitant medications.

 Results:
 Preliminary analysis of 502 participants (395 AA, 104 CAU, and 3 others) shows racially different polymorphic prevalence. Reduced activity of CYP3A4 was present in 5.8% CAU vs 0.51% AA. Notably, CYP3A5*3 is inactive in 73% and reduced in 20.3% of CAU compared to 41.7% and 40.7% respectively in AA. A statistically significant increase in SI in AA women vs CAU women (p=0.0032) was observed. In combined analysis, atorvastatin has reduced odds of intolerance compared to simvastatin (OR=0.463; p <0.05). However, the odds of SAM is higher in patients with no history of cardiovascular disease (OR=6.137; p <0.01) and those with chronic kidney disease (OR=1.269; p <0.05).

 Clinical significance:
 Considering, the CYP3A5 is fully active in 18.5% of the AA population compared to 6.8% CAU, the characterization of this metabolic enzyme is of clinical significance in minority populations to better manage lipidemia, assess the safety profile of current therapeutic doses, and reduce SAM.


There are often special terms which are not easily understood by everyone in a civil dispute that lawsuit is submitted to a district court. This research is interdisciplinary research conducted to contribute to law and linguistics. The data was from the lawsuit, answer, replicate, and duplicate discourse, as well as a verdict on the civil dispute in the District Court in Indonesia. The results of the legal register analysis' study on the discourse of civil dispute are; the register forms on the discourse of civil dispute are 30 registers, Language aspects that are utilized in civil dispute can be seen in the use of long sentences and the use of words derived from Dutch. The structure that is characteristic of civil dispute consists of the structure of lawsuit, answers, exceptions, replications, duplicates, and verdict.


Even in highly developed western regions, huge riveraine floods are a great challenge for flood response management. The cooperation of different response authorities and organizations under time critical conditions in a highly dynamic environment require support with modern IT methods and systems. Present Flood Information Systems still do not sufficiently focus on supporting the workflow of planning and carrying out flood response actions. This paper introduces a new process centric approach, which improves the coordination and information workflows of Emergency Operation Centers (EOC) and involved services. Formal process models as core of a process driven emergency management platform provide the responsible agent with appropriate data and analyses along defined emergency processes. The platform guides the EOC officers and involved parties through the organizational steps of flood response actions. Coordinated information flow and automatic multi-channel notifications are ensured throughout the process. The developed approach is successfully validated using flood scenarios with real-world data. The results show that the approach improves information flow in the EOC and to external organizations and enhances coordinated work-sharing of EOC team members during flood response.


When characterizing semiconductor components to determine their ESD robustness using a transmission line pulse test system, there is no universally accepted standard procedure for performing the test available at present. In this paper, we address this issue whereby we study the impact of the following TLP characterization related variables: failure criterion, influence of stress step-size and cumulative stress effects. We show that the failure criterion, `any increase in leakage', yields the most reproducible and reliable results in the devices tested.


Cost functions that involve complex simulations are becoming more common for engineering design problems. Such cost functions are very CPU intensive and their optimization by exact algorithms need complex computations. There are some approaches in the literature to decrease the overall computational time. It needs some experience to know the suitable evaluation algorithm for a defined problem. However, finding the optimum point in a short search time needs an intelligent search algorithm. In this article, a new solution approach is proposed to achieve near global optimal point in a reasonable time for complex cost functions. The proposed approach has been implemented for some test functions. The results show that this approach has better performance comparing to other existing solution algorithms such as Genetic Algorithm, Differential Evolution, Evolution Strategy, and Particle Swarm Optimization.


The mechanism of therapeutic action of antidepressant drugs has been related to their effects on metabolism and release and reuptake of catecholamines and serotonin. Some atypical antidepressants, however, do not have such pharmacological effects. Recently it has been reported that most of the antidepressant drugs cause down regulation of beta adrenergic receptors in rat brain after chronic treatment. In order to examine if this is a common and specific pharmacologic property of all antidepressant drugs, we have studied the effects of treatment with some atypical antidepressant drugs on beta adrenergic receptor binding in rat cortex using 3H‐dihydroalprenolol (DHA) as the radiolabeled ligand. Our results indicate that chronic treatment with almost all antidepressants studied causes down regulation of beta adrenergic receptors. However, such effects are not observed after treatment with neuroleptics such as haloperidol or chlorpromazine or psychomotor stimulants such as cocaine. This approach thus provides a useful method of screening potential antidepressant drugs.


Good habit is everything, say health experts. You can't stay healthy unless you intend to, and, follow good habits. From morning to night, you ...


MATSUMOTO, J., MURATA, T., SATO, S., ICHIHARA, T., HARUYAMA, T., URUGA, K. and KANEDA, H. Echocardiographic Diagnosis, Classification, and Dialysis Treatment of Uremic Pericardial Effusion. Tohoku J. exp. Med., 1980, 130 (3), 265-272 Uremic pericardial effusion (UPE) was found by echocardiography in 61 (47%) out of 131 uremic patients. According to the echocardiographic findings, accompanying diseases and the response of UPE to the dialysis treatment, we tried to classify UPE into three main groups; uremia alone (40 patients-66%), uremia with infection (14 patients-23%), and uremia with other diseases (7 patients-11%). 1) UPE was recognized in 25 uremie patients (35%) among 65 subjects without dialysis treatment but having the serum creatinine levels higher than 5.0 mg/100 ml. The incidence of UPE was progressively increased with the elevation of serum creatinine levels (53% of patients with the serum creatinine levels higher than 10.0 mg/100 ml). 2) Uremia with infection group had some infectious signs; fever, leukocytosis, elevated erythrocyte sedimentation rate and sometimes pleuritis. 3) Uremia with other diseases group was those patients whose underlying diseases were other than chronic glomerulonephritis, such as hepatorenal syndrome, lupus nephritis, diabetic nephropathy and Alpert's syn drome. The echocardiographic detection of UPE proved to be convenient for early diagnosis of it and should be performed routinely in regularly dialysed patients. -.. diagnosis and classification of uremic pericardial effusion; echo cardiography; dialysis treatment


This article is a library research which aims to reveal the interconnectivity of hadith with science, with the hadith about flies as a case in point. At least, there are 4 patterns of relationship between religion and science, namely conflict, independence, dialogue, or integration. Without reflecting on these 4 patterns, the principle of understanding religion will not be possible to do perfectly, because it is separate from the reality of human life. By using thematic methods and historical-sociological approaches to these hadiths, this article arrives at the findings that most of the microorganisms such as germs, viruses and microbes that are present in the body of flies can cause a number of diseases, but the micro development of living things on the fluids they inhabit can neutralized by submerging it. This proves that the discovery of science is in harmony and synergy with the hadith of the Prophet.


Coal-fired power plants are undergoing ultra-low emission retrofits. When the flue structure of the SCR denitrification system of the existing unit is fixed, the internal baffles and static mixers need to be optimized to ensure the flow field uniformity, thus ensuring the denitrification efficiency and controlling the ammonia escape rate. For a 660 MW SCR system, numerical simulation of flue gas flow uniformity and cold state test of physical model were carried out. The results show that the uniformity of the flow field distribution and the mixing effect of ammonia and gas in the SCR denitrification system are effectively improved by adding deflectors and optimizing the static mixers. The research in this paper provides reference for similar engineering design and construction in the future.


BSI Quality Assurance is the certification business of the British Standards Institution. They believe that they are the largest and most active third-party certification body in the world. The author describes the role of BSI QA in software quality assurance and in the TickIT software certification scheme. He also examines the involvement of BSI QA in the establishment of accreditation criteria for certification of software developers.


In this study, we applied constructive approach to education supplemented with the innovation cycle approach. The main goal is to develop the innovative ideas from a clear start up to the implementation phase. Since multiple ideas tackle multidisciplinary problems, to properly present all needed concepts we used teachers from different fields of science. This was implemented through a pilot project and all results were assessed using a quasi experimental approach and constructive qualitative methodology to show the increase of interest with students in the areas of innovation, constructivism, and multidisciplinary on the cognitive, behavioral, and the affective level.


The invention discloses a data verification backup, writing and reading method for a triangle type memory device. The triangle type memory device comprises a ferroelectric memory, a first flash memory and a second flash memory. The data memory backup method comprises the steps of reading data in the ferroelectric memory; verifying the data; backing up to the first flash memory and the second flash memory after successfully verifying. The data writing method comprises the steps of reading bad block areas of the first flash memory and the second flash memory from the ferroelectric memory; respectively writing real-time data into block areas outside the bad block areas of the first flash memory and the second flash memory. The data reading method comprises the steps of reading real-time data of the first flash memory; verifying; returning after failing in verification; continuously reading and verifying until the failure times reach the preset times; reading the real-time data stored in the second flash memory. With the adoption of the data verification backup, writing and reading method for the triangle type memory device, the safety and accuracy of the data can be improved.


Applying GTAP model,this paper does a computable general equilibrium analysis on the impact of China- India FTA's construction on both sides and the world economy from aspect of trade scale,trade structure, GDP and the social welfare.The result indicates that,the inter-industrial and intra-industrial trades be- tween both sides enlarge significantly,industrial gradient transfers acceleratedly;services are the inferior industries for China and suffer great negative impact;India's agricultural products are not affected sub- stantially,its manufactures benefit evidently and its industrial structure tends to relative balance;China's terms of trade,GDP and the national welfare improve,while India deteriorate correspondingly;as a whole,the FTA still display great benefit spillover effect,the world total welfare improves markedly.


Hazardous material transportation is a significant issue in relation to both environment and humanity. In recent years, studies and attempts to minimize the risks of hazardous material transportation or selection of transportation mode to reduce potential hazards have increased. This study aims to evaluate the hazards arising from each stage of hazardous material transport modes and the risks arising from these hazards with an integrated approach simultaneously. Fault tree analysis (FTA) is used to evaluate hazardous material transportation modes with their stage components; probabilities of potential hazards are calculated for the risks arising from those hazards and evaluated with The Decision Making Trial and Evaluation Laboratory (DEMATEL) approach. Last, to determine the critical levels of transportation modes, calculated risk scores and parameters that affect those transportation modes, such as speed, cost, and capacity, are assessed with Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) and DEMATEL approach. Ultimately, critical levels of transportation modes are ranked as highway, marine and inland, airway, and railway.


BACKGROUND
Anemia is a common complication of advancing chronic kidney disease, yet little is known about the consistency of anemia treatment before end-stage renal disease (ESRD) and mortality on dialysis therapy.

METHODS
We studied 89,193 incident Medicare patients with ESRD in 1995 to 1997 aged 67 plus years with claims 2 years before their dialysis therapy initiation. Patients were classified as follows: no epoetin, 25% or less (least consistent), greater than 25% to 50%, greater than 50% to 75%, and greater than 75% (most consistent) epoetin treatment in the available months from the first pre-ESRD epoetin dose to the first ESRD service date. Cox regression modeled the risk for 1-year death in the post-ESRD period, adjusting for age, sex, race, diabetic status, albumin level, and incidence year.

RESULTS
Sixty percent of patients had hematocrits less than 30% at ESRD initiation, yet only 15.6% (N = 13,877) had epoetin claims before ESRD. The most consistent epoetin treatment group had hematocrits increase from 27.5% to 30.8% (P < 0.0001) by month 4 of treatment. Patients with the most consistent epoetin treatment had a greater mean hematocrit (29.2% +/- 0.11%; P < 0.0001) and albumin level (3.31 +/- 0.01 g/dL [33.1 g/L]) at initiation than those with the least consistent treatment (28.1% +/- 0.10% and 3.21 +/- 0.01 g/dL [32.1 g/L], respectively). The relative risk for death in patients with the least consistent versus the most consistent (the reference) epoetin treatment was 1.460 (95% CI, 1.245 to 1.713; P < 0.0001) 1 year after the first ESRD service date.

CONCLUSION
Elderly patients with consistent pre-ESRD epoetin treatment had lower risks for death in the first year of dialysis therapy after ESRD initiation.


As the use of smartphones and social media spreads, the market size of online video advertising is expanding rapidly. In the United States, the Internet advertising market in 2017 exceeded the television advertising market. In Japan, the size of the video advertising market in 2017 was 137.4 billion JPY, which is 163% of the value the previous year, and it is expected to increase in the future. Video content is becoming more accepted in communication between companies and users. However, advertisers are struggling to measure the degree to which user emotions have been successfully triggered. The purpose of video advertising is to make the target market aware of goods and services (awareness), to consider purchasing (consideration), and finally to achieve sales (action). Important criteria for measuring the attainment of these goals are ad liking and purchase intent. Recently, research has been conducted to predict advertisement effectiveness from viewers' facial expressions and physiological responses 1)~4). Facial expressions have been shown to predict ad liking, which is a relatively simple emotion, but purchase intent, which is relatively vague, cannot be accurately predicted. To improve the prediction accuracy of purchasing intent, it is useful to analyze physiological responses, such as heart rate (which can estimate ambiguous emotions), as well as consumer personality and to use multimodal features combined with facial expressions. In addition, because Japanese people have brief facial expressions5), it is more difficult to estimate emotions in Japanese from expression alone than in viewers from other countries. Traditionally, consumer testing of video ads, whether self-reported, facial, or physiological, has been performed in a laboratory setting. Research in a laboratory environment has many advantages, including the ability to measure facial expressions and physiological responses with high accuracy. However, subjects can be influenced by factors unrelated to the stimulus being studied, such as the presence of the experimenter and the comfort of the experiment environment. Because it is difficult to quantify these effects, it is necessary to measure the degree of emotional inducement in a real environment that does not cause discomfort to the subject. Furthermore, computer-based machine learning and pattern analysis rely heavily on the number of training samples. In this paper, we use crowdsourcing and the nonAbstract The market size of online video advertising is expanding rapidly along with the spread of smartphones and social media. In this study, we estimate advertising effectiveness in the natural environment using online data collection and the remote measurement of webcam facial expressions and physiological responses. We collected 4, 108 videos of the faces of 411 Japanese people who were watching the video advertisement in their natural environment via the Internet. Facial expression and physiological responses such as heart rate and gaze were remotely measured by analyzing facial videos. We found that the accuracies of ad liking and purchase intent prediction are better when various acquired features are combined and machine learning is used than when only single-mode features are used. In addition, we aim to improve prediction accuracy by clustering the personality of the subjects and designing an estimation model for each personality.


Nutritional, rheological, and sensory evaluation for Tere (Rokak) bread supplemented with 0, 2.5, 5, 7.5, and 10% of inulin or wheat bran were studied. The chemical composition of bread was slightly affected by these treatments, while energy values were reduced from 354.24 to 315.76 calories/100g. The results showed that Farinograph water absorption decreased from 70.2 to 50.3% and Mixing Tolerance Index from 34 to 0.00 BU with an increase in development time from 9.3 to 20 min, stability time from11-14.9 min, and quality number from 138-200 by increasing of inulin addition. The most pronounced effect of bran addition was on Farinograph stability and quality number which decreased from 9.3min and138 to 6.9min and 117 respectively. On the other hand, inulin decreased the Amylograph viscosity peak at heating from 840 t0 610 BU and the final viscosity at cooling from 1250 to 990 BU. Inulin addition significantly reduced the amount of required water to make Tere bread from 66% to 54% compared to control and bran. Inulin reduced about 3cm of bread diameter, while 7.5% of bran addition increased 3cm of Tere diameter. Also, the sensory evaluation showed that inulin and bran addition up to 10% had a slight effect on Tere bread compared to control , and their total acceptability was 70%-80%. No mold growth was observed on stored bread for three months which emphasized their resistance to any visible growth.


plasma membrane potential dependence. Circulation 1990; 82: 1826–38. 4 Gimelli A, Rossi G, Landi P, Marzullo P, Iervasi G, L'Abbate A et al. Stress/rest myocardial perfusion abnormalities by gated SPECT: still the best predictor of cardiac events in stable ischaemic heart disease. J Nucl Med 2009; 50: 546–3. 5 Cantoni V, Green R, Acampa W, Petretta M, Bonaduce D, Salvatore M et al. Long-term prognostic value of stress myocardial perfusion imaging and coronary computed tomography angiography: a meta-analysis. J Nucl Cardiol 2016; 23: 185–97. 6 Naya M, Tamarki N. Stress MPI, coronary CTA, and multimodality for subsequent risk analysis. J Nucl Cardiol 2016; 23: 198–201.


The seeds and seedlings of pepper were handled by the various concentrations of cinnamaldehyde. The effects of cinnamaldehyde on the seed germination,the growth,the chlorophyll content,root activity and the change of antioxidant enzymes in pepper were studied in this paper. The results showed that the change of germination energy was no significant difference in the 50 mg / L cinnamaldehyde concentration,whereas it markedly decreased with the rising of the cinnamaldehyde concentration. When the cinnamaldehyde concentration was less than 300 mg / L,the germination percentage was no significant difference compared with the control,whereas the germination index and the vigor index markedly decreased with the rising of the cinnamaldehyde concentration. The shoot height was no significant difference in the 50 mg / L cinnamaldehyde concentration,whereas it markedly decreased with the rising of the cinnamaldehyde concentration. The root length, fresh weight and dry weight had the same trend as the shoot height. When the cinnamaldehyde concentration was less than 150 mg / L,the chlorophyll content significantly increased compared with the control. When the cinnamaldehyde concentration was more than 150 mg / L,the chlorophyll content had some extent decrease. However,it had no significant difference compared with the control. Under the treatment of cinnamaldehyde soaked seeds the root activity showed the trend of increase-decrease with the increase of cinnamaldehyde concentration, whereas the antioxidant enzymes activities of SOD,POD and CAT gradually decreased. But SOD and POD activities were no significant difference compared with the control in the 50 mg / L treatment. All the results showed that the seeds of pepper could be deal with the lower concentration cinnamaldehyde to inhibit and control Phytophthora blight.


AbstractThe taxi–passenger problem is more and more prominent in terminal stations; passengers usually wait in a long queue for taking a taxi in rush hour, and otherwise taxis wait in a queue for p...


Since completion of the Luhun reservoir spillway tunnel in 1965, the lining concrete quality deteriorated gradually, having resulted in very serious damage of concrete cracks. According to the analysis on the basis of spillway tunnel quality test and evaluation, such factors as excessive external load, temperature stress and plastic shrinkage of concrete are the reasons of occurring and development of spillway tunnel cracks. The cracks were treated with TH-1 polyurethane grouting material with the features of low viscosity, good grouting property and higher binding strength. The compressive and tensile strength of the solidified grouting compound are higher and remedy result is quite satisfactory and construction is easier. The higher efficiency and fast construction speed are especially favorable for ensuring the grouting quality.


GeoDCAT-AP is a metadata profile aiming to provide an RDF-based representation of geospatial metadata compliant with the DCAT application profile for European data portals (DCATAP), specifically designed to enable the sharing of geospatial metadata, in particular those available via the INSPIRE infrastructure. In this paper, we provide an overview of GeoDCAT-AP, and we outline the lessons learnt, in particular with respect to the issues concerning the cross-domain integration of the geospatial platform with other data infrastructures. Disclaimer: The views expressed are purely those of the author and may not in any circumstances be regarded as stating an official position of the European Commission.


The research has produced a system of tasks which allows to develop junior pupil`s consciousness. In the future it will give the society adults with original consciousness able to solve non-standard puzzles.


In this paper, I don't use the word of "geomancy" but use "feng-shui", as meaning a set of method and concept for an assessment for environmental impact against human life. Environmental impact assessment, connected with the feng-shui theory of later eras, first began with xiang-zhai (house and community observation), which appeared in the Zhou Period (770~256 BC.), Spring and Autumn/Warring States Periods(770~221 BC.) in China. Now I recognize the meanings of feng-shui are indicated two kinds. One meaning is a kind of scientific thought through the ancient environmental impact assessment, and another meaning is a method of divination through judgments fortune-telling items. So I will mention about the Japanese history of feng-shui divided into two kinds of histories. A number of scholars have pointed out the transmission of feng-shui knowledge to Japan, as recorded in the section of the Nihon Shoki (the Book of the ancient Japanese record) which reads: "In 601 AD, a buddhist monk named Kanroku arrived from Paekche (one of the country, ancient Korea) to Japan. As tribute, they brought books of astronomy and geography (same meaning of feng-shui)...". After this record, terms synonymous with feng-shui can be sporadically seen in the records of ancient Japan. Continuing, in the Book of Ryo-no-gige (chapter of staff instructions) of the 9th century in Japan, it states that 6 yin-yang practitioners of the yin-yang Bureau (Ministry of astronomical and geographical observations) "shall be in charge of divination sticks and souchi (feng-shui)". Thus, one of the duties of the yin-yang practitioners was souchi. This was a form of divination and observation topography which was a predecessor of the feng-shui theory. Much later in time, we arrive at the Edo Period (1603~1868 AD.). In Wakan-sansai-zue, or Sino-Japanese encyclopaedia from this Period written by Terashima Ryoan, the compass (which


AT the base of the flanks of a desert mountain, conditions are propitious for deposition by streams coming from the highlands. There is usually a decrease in gradient at canyon mouths, and all streams undergo a reduction of velocity and transporting power at these sites. Velocity loss is due both to lessened gradient and to decrease in volume by seepage into loose, permeable materials. Deposition is the natural result, and alluvial fans are the landforms produced. Alluvial fans built by concentration and movement of debris in trunk canyons accumulate at the foot of the mountain mass. Their upper portions are separated by interfan depressions, but their lower surfaces coalesce to form piedmont alluvial plains, or bajadas. This study is a contribution toward an understanding of depositional processes and the landforms produced by them in the southwestern United States. The evidence comes from the White Mountains of California and Nevada, a high-standing desert range at the western margin of the Great Basin. Particular attention was given to the western flank of the mountains, but the larger fans and associated drainage basins on the east side were also investigated. Conclusions reached about alluvial fan formation are thus based upon study of depositional features of diverse morphology and size.