The first woman to lead the U.S. National Institutes of Health was tenacious about eliminating gender discrimination in the sciences. I met Bernadine Healy in 1991 when I served on the Director's Council of the U.S. National Institutes of Health (NIH). She was a kind and thoughtful friend. But most people, particularly women, who never knew the only woman to lead the NIH continue to benefit from her remarkable life, which sadly ended 6 August after a 12-year battle with brain cancer.


When exciting a ferromagnetic film with a femtosecond optical laser pulse, then there is a partial demagnetization within a few hundred fs. This means that the angular momentum of the electronic system is transferred to the lattice. This transfer is calculated by describing the lattice degrees of freedom as spin-phonon eigenmodes which have a sharp angular momentum. Possible other lattice degrees of freedom are mentioned but not considered explicitly. For Ni and Fe the calculated amount of transfer of angular momentum to the spin-phonon eigenmodes is rather small.


Background: Several markers of systemic inflammation seem to play an active role in the pathophysiology of acute coronary syndrome and its evolution. High mobility group box-1 (HMGB-1), a ubiquitous nuclear protein constitutively expressed in quiescent cells, was recently recognized as a newer critical mediator of inflammatory diseases. The present study aimed to evaluate the possible association between HMGB-1 levels and structural and functional indices of cardiovascular performance such as cardiopulmonary and Doppler-echocardiography indices in patients after acute myocardial infarction (MI). Methods and Results: Fifty-four consecutive patients (mean age 58.3 years, 83% males) recovering from acute MI were included in the study protocol. All patients underwent Doppler-echocardiography, cardiopulmonary exercise, and HMGB-1 assay. HMGB-1 levels in acute MI patients were significantly higher compared with age- and body mass indexematched controls (14.8 6 6.8 vs. 2.3 6 1.0 ng/mL, P ! .0001, respectively). Postinfarction patients showed oxygen consumption at peak exercise (VO2peak) 5 14.4 6 4.2 mL$kg$min and a slope of increase in ventilation over carbon dioxide output (VE/VCO2slope) 5 32.1 6 6.2, whereas Doppler-echocardiography values were: left ventricular end-diastolic volume (LVEDV) 5 53.4 6 8.2 mL/m 2 ; left ventricular ejection fraction (LVEF) 5 41.7 6 7.0%. Multiple linear regression analysis (stepwise method) showed that VO2peak (b 5 e0.276, P 5 .012), VE/VCO2slope (b 5 0.244, P 5 .005), LVEDV (b 5 0.267, P 5 .018), peak creatine kinase-MB (b 5 0.339, P 5 .004), peak Troponin I (b 5 0.244, P 5 .002), and LVEF (b 5 e0.312, P 5 .021) were significantly associated with HMGB-1 levels. Conclusions: The present study demonstrated that in postinfarction patients, HMGB-1 levels were significantly higher compared with controls, and significantly correlated with cardiopulmonary and Dopplerechocardiography parameters. (J Cardiac Fail 2009;15:362e367)


The main objective of the current work was to develop a study to determine the feasibility of implementing a company dedicated to the production and commercialization of dehydrated jackfruit in Huaquillas canton, at Oro Province, which will serve as a guide to generate a new business project that provides consumers with products that are healthy, natural and contribute to enrich the daily diet of the general population.
For which the application of deductive, statistical and analytical methods was determined. In addition, data collection techniques such as survey and direct observation were designed.
To determine the feasibility of the project, it began with the market study with a sample of 374 families, it was determined that the effective demand is 198,584 potential customers, as for the offer is 91,930 people who buy dehydrated fruit. Regarding unmet demand there are 106,654 potential customers.
Through the technical study it was determined that the installed capacity of the project will be 147,825 annual production in pounds, while the used capacity will be 35,100 annual production in pounds, the company will be located in the downtown of Huaquillas canton, on Esmeraldas and Hualtaco avenues.
In the productive process, it demands the use of adequate machines and equipment, physical distribution, the process diagrams, the establishment of the company and other items that make up the start-up of the business were established.
In the financial study it was established that the project reaches an initial investment of
5
$ 47.562,92 dollars, fixed assets with a total of $ 32.306,00; deferred assets $ 1.858,00 dollars and a working capital of $ 13,398.92. the financing will be 58% of the capital from the partners and 42% financed by BanEcuador.
Finally, the financial evaluation determined that the Net Present Value (NPV) which obtained a positive result at $ 61.229,78 the Internal Rate of Return (IRR) is 50.50%, the Cost Benefit Ratio (CBR) was obtained for each invested dollar you get 0.24 cents of return, the Period of Recovery of Capital (PRC) was determined that the investment is recovered in 1 year 11 months and 16 days, finally the Sensitivity Analysis with increase in costs is of 11.03% and a decrease in income of 8.98%, which indicates that it is feasible to start the project, which conclusions and recommendations determine it.


This article presents data on the legal restrictions to the replacement of striking workers in 28 OECD countries. Our main result is that some form of replacement is allowed in most countries. In particular, some form of replacement is allowed in 17 countries. On the other hand, four countries explicitly forbid any form of replacement during strikes. In those countries that allow replacement, five countries place no restrictions on the hiring of external workers to replace striking workers, while four allow it as long as those workers are not hired through a temporary employment agency.


We have investigated sound wave propagation in helium and argon gases at low gas pressure. At pressure around 50 mtorr for argon and 30 mtorr for helium and sound source frequency of 40 kHz, the phase velocity of sound wave increases with a decrease in pressure, which agrees well with the theoretical prediction based on Navier‐Stokes equation. At a very low pressure ( 5 mtorr ) of helium gas, the wave propagation shows pseudo wave property that the phase velocity is increasing as distance from sound source increases.


A trial installation of a wingtip parachute has been made on a De Havilland Venom N.F.3 aircraft to check its safety and performance before use on the Fairey Delta 2. The opportunity was also taken to measure the rudder power and the directional stability derivative nv, of the Venom. The arrangements for streaming and jettisoning the parachute proved safe and satisfactory. The values of the directional stability derivative measured by the parachute method agreed well with values from Dutch roll tests, also made on this aircraft.


In this paper, a miniaturized circularly polarized filter feed horn working in V-band is proposed. It consists of a third-order Chebyshev bandpass filter (BPF) with multi-layer gap waveguide (GW) structure and a circularly polarized horn antenna. Among them, the horn antenna is designed with an open slotted end structure, and the BPF is designed with a three-layer stacking structure based on GW to achieve circular polarization and miniaturization, respectively. The simulated results show that the filter feed horn has a working frequency of 59 - 64 GHz, a fractional bandwidth of 8.95 %, a gain of 10.5 ± 0.5 dBic, an axial ratio of less than 1 dB, which has a good electrical performance.


FIELD: medicine. SUBSTANCE: implant device for blood vessels of humans and animals has the form of flexible cylindrical mesh shell with inner radius R, which contains at least four reinforcement rods made from a material with residual deformation, which are attached to the inner surface thereof along a helical path of one turn with the ability to twist this design to the radius R1<R, sufficient for a passage in the vessel, by means of strips of flexible adhesive tape. EFFECT: application of an implant device for human and animal blood vessels simplifies the design, reduces the operation time and improves its efficiency by creating helical movement of blood in its cavities. 3 cl, 3 dwg


Objective: Propose a post-surgical rehabilitation program identifying the steps necessary for a progressive recovery of the joint function in compliance with the surgical needs. Material & method: In the anterior and posterior glenohumeral instability, the presence of bone defects, especially at the glenoid side requires surgery and the use of the bone block, associated with the repair of the soft tissues (capsuloplasty). The arthroscopic technique, compared to open surgery, allows respecting the periarticular anatomical structures, essential for optimal functional recovery. Results: The post-surgical rehabilitation program follows a progressive recovery timing, divided into 3 phases: phase 1 pain control and joint mobility recovery, phase 2 the recovery of strength and specific sport movements and finally phase 3 the return to sports activities. The rehabilitation progress must achieve two objectives: ROM recovery without disturbing the bone graft area, to achieve its integration. Conclusion: the rehabilitation program is ultimately guided by the surgeon considering the strategy adopted in the operating room, the use of the bone-block technique and above all the sealing of the grafts. The physiotherapist following the proposed steps will optimize the final functional result.


Background and Objective: Alzheimer's disease (AD) is a neurodegenerative disorder which is associated with extracellular accumulation of amyloid beta (Aβ) plaques. AD is accompanied by mitochondrial dysfunction and energy metabolism reduction. Fibroblast growth factor 21 (FGF21) is an endogenous polypeptide which its beneficial effects have been demonstrated on mitochondrial function, energy metabolism regulation and neuroprotection. Materials and Methods: The present study was performed to investigate the effect of pretreatment with different concentrations of FGF21 [100,200 and 400 nM] on SH-SY5Y cells as a cellular model of AD induced by Ab(1-42). For induction of cellular model of AD. Ab(1-42) [20 µM] was added to SH-SY5Y cell medium. Cell viability (MTT assay) and mitochondrial membrane potential changes (Rhodamine 123 fluorescence intensity) were measured using microplate reader. Results: The results of this study showed that Ab(1-42) enhances cell damage (p Conclusion: Taken together, the results of this study suggest that FGF21 prevents cell death induced by Ab(1-42) in SH-SY5Y cells. It seems that the beneficial effects of FGF21 are mediated through mitochondrial membrane potential maintenance.


Polyoxyl hydrogenated castor oil document, Jun. 1999, p. 1.* International Preliminary Report on Patentability issued May 21, 2010, in PCT International Application No. PCT/JP2010/058676. International Search Report for PCT/JP2010/058676, mailed on Jun. 22, 2010. P. Ratanabanangkoon et al., "A high-throughput approach towards a novel formulation offenofibrate in omega-3 oil". European Journal of Pharmaceutical Sciences, vol. 33, 2008, pp. 351-360.


We're used to saying that works of art are the mirror of History. In this paper, we explore the historical and artistic context in Compostela between the nineteenth and twentieth century, a vibrant epoch often forgotten in the studies, throughout a series of pieces of silversmithing by the artist Ricardo Martinez. Being the sumptuary arts a key element, quite ignored by the historiography of the art from Compostela, this text aims to demonstrate how artistic fields like silversmithing and other artistic Arts-and-Crafts from Santiago can contribute to build its historiographical state of art.


Abstract : Retinal Derived Growth Factor (a heparin binding growth factor that is identical to aFGF (acidic Fibroblast Growth Factor)) stimulates neurite outgrowth in vitro. We have established a model system that will allow us to determine if a gradient of FGF can cause nerve regeneration in vivo and that this regeneration is predominantly due to increased neurite outgrowth by sensory nerves. (kt)


The article describes I. A. Tikhomirov, a famous scientist and organizer of popular schooling in the Ural, in the period of his studies at St. Petersburg Imperial Historical-philological Institute in the context of historical reconstruction of his life.


Abstract The effect of carbon black on nanoclay filled polychloroprene (CR) composites has been investigated. The nanoclay loading is fixed at 5 part per hundred rubbers (phr), and carbon black loading varied from 5 to 20 phr in rubber compounds. The rubber nanocomposites are prepared in laboratory by mixing in two-roll mill. The addition of nanoclay enhances mechanical properties especially tear strength and decreases water absorption without change in electrical properties compared to gum rubber vulcanisates. Wide angle X-ray diffraction and transmission electron microscopy are used to study the microstructure of CR nanocomposites. The addition of 5 parts of nanoclay to 15 phr carbon black filled samples shows synergistic effect between the fillers and suggests that the reinforcement is due to a more developed filler network formation in hybrid filler system than that in single phase filler. Significant improvement in mechanical, electrical and low water absorption properties has been obtained with these nanoclay and carbon black filled rubber nanocomposites. The paper concludes that nanocomposites containing a mixture of organoclay and carbon black in right proportion can be a substitute for rubber components used in underwater cable and device encapsulation applications.


Objective The aim of this study was to investigate outcomes in uterine cancer patients undergoing pulmonary metastasectomy and prognostic factors associated with survival after the procedure. Methods A retrospective study was performed in 29 uterine cancer patients who underwent surgical resection of pulmonary metastatic lesions at Samsung Medical Center between June 1995 and December 2011. Results Histopathology showed carcinoma in 17 patients (58.6%) and sarcoma in 12 patients (41.4%). Of the 29 patients, 17 (58.6%) had less than three pulmonary metastatic lesions. Eight (27.6%) had symptoms related to lung metastasis. The 5-year survival rate after pulmonary metastasectomy for the entire cohort was 48.2%. On univariate and multivariate analysis, the presence of pulmonary symptoms and more than three lesions of metastasis were associated with poor survival after pulmonary metastasectomy. Conclusion Pulmonary metastasectomy for uterine cancer is an acceptable treatment in selected patients. Patients with more than three pulmonary metastatic lesions and pulmonary symptoms related to lung metastasis could expect to have worse prognosis after pulmonary metastasectomy.


Preface Abbreviations Introduction 1. Perfective and imperfective 2. Aspect and inherent meaning 3. Perfect 4. Aspect and tense 5. Formal expression of aspectual oppositions 6. Markedness Appendices References Index.


Cross-cultural skills are one of 21 century student outcomes. According to cultural competence of nursing profession, it is very importance to challenge for nursing education. This article prosented defini-tion of culture and cultural competence. The authors indicated 3 practice guidelines for improve nursing education: (1) integrating cultural concept in to nursing curriculum, (2) adding course of cultural compe-tence into the curriculum, and (3) research and development for enhancement culturally competence of nursing instructors, nursing students, organization, and interdisciplinary education. Key words: culture, cultural competence, nursing education, nursing instructors


The transmural fluxes of L-Leucine and L-Tyrosine were measured by in the intestinal gut,using the in vitro perfusion technique. The transmural rates of L-Leucine are 0.026,0.062 and 0.038(μmol/g/min)when the concentrations of the perfusion Leucine are 1.0,5.0 and 10.0mmol/L at the 10 min respectively. The transmural rates of L-Tyrosine are 0.006,0.024 and 0.039(μmol/g/min)when the concentrations of the perfusion L-Tyrosine are 0.5,1.5 and 2.5mmol/L the 10min respectively.The total absorption ratios of the L-Leucine are 12.83%,18.85%and 16.45% when the concentrations of the perfusion L-Leucine are 1.0,5.0 and 10.0mmol/L for 40 minutes respectively. The total absorption ratios of the L-Tyrosine are 22.18%,23.68% and 27.49% when the concentrations of the perfusion L-Tyrosine are 0.5,1.5 and 2.5mmol/L for 40 minutes respectively. The percentage of the transmural fluxes through the intestinal gut,the free in intestine,that in new synthesized protein and the remainders in intestine to the total absorbed amino acid were calculated respectively. When the concentration of the perfusion L-Leucine are changed from 1.0mmol/L to 5.0mmol/L and 10.0mmol/L,the transmural ratio are 83%,66% and 35% respectively. The free in intestine are 9%,28% and 49% respectively. That in protein are 2%,5% and 13%. The remainders are 6%,1% and 3% respectively. When the concentration of the perfusion L-Tyrosine are changed from 0.5mmol/L to 1.5mmol/L and 2.5mmol/L,the transmural ratio are 52%,55% and 55% respectively. The free in intestine are 7%,10% and 16% respectively. That in protein are 17%,15% and 16%. The remainders are 24%,20% and 13% respectively.


The increasing interest in the use of a wide range of colours in buildings, especially dark colours, may lead to the early degradation of the façades, compromising their aesthetic and thermal performance. On the other hand, the incorporation of nanopigments with high reflectance properties can contribute to reducing the absorption of solar radiation. The nanoparticles contribute to increasing the solar reflectance of coatings, decreasing the surface temperature and improving the coating performance. This work evaluates the natural degradation of the colour of finishing coat with nanopigments in ETICS. The colour parameters were evaluated in different ETICS specimens, considering the colour black and red with and without incorporated nanopigments, under natural ageing. The colour measurement was performed according to ISO 1164-4, using a portable spectrophotometer. The results confirmed that the use of nanopigments improved the colour durability, promoting the maintenance of the colours parameters. The total colour difference was lower than the perceptible by the human eyes, even as the lower variation on chroma and hue parameters of the colours with nanopigments. In summary, the incorporation of nanoparticles in finishing coat of ETICS can contribute to increasing their durability and improve their thermal performance without compromising the aesthetic characteristics.


PART 1: CONTEXT. Chapter 1: Background and influences. Part 2: HELPING OLDER INDIVIDUALS. Chapter 2: Older individuals and mental health. Chapter 3: Normal physiological ageing. Chapter 4: Values underpinning help, support and care. Chapter 5: Approaches to help, support and care. Chapter 6: Legal and ethical frameworks for mental health nursing. Chapter 7: Dilemmas in mental health nursing. Chapter 8: Assessing older people with mental health issues. PART 3: NEGLECTED ASPECTS. Chapter 9: Culture, religion and spirituality. Chapter 10: Intimacy, sex and sexuality. Chapter 11: Nutrition. Chapter 12: Palliative and end-of-life care. PART 4: MENTAL HEALTH ISSUES FOR OLDER PEOPLE. Chapter 13: Acute mental health issues. Chapter 14: Delirium. Chapter 15: Enduring mental health issues. Chapter 16: Depression in later life. Chapter 17: Dementia in later life. PART 5: FUTURE DIRECTIONS. Chapter 18: Mental health and well-being for older people in the future: the nursing contribution


TPS3103Background: No approved standard-of-care treatment options exist for patients with unresectable HCC who progress on, are intolerant to, or have refused sorafenib therapy. The PD-1/PD-L1 pathway is an important immune checkpoint used by tumor cells to block antitumor responses. Durvalumab is a selective, high-affinity human IgG1 monoclonal antibody that blocks PD-L1 binding to PD-1 (IC50 0.1 nM) and CD80 (B7.1; IC50 0.04 nM). Tremelimumab is an IgG2 monoclonal antibody that inhibits CTLA-4. Tremelimumab monotherapy can induce objective tumor remission with a favorable safety profile in patients with HCC.1Targeting both PD-L1 and CTLA-4 pathways provides nonredundant pathway blockade of critical immune checkpoints. Methods: This phase 1/2, multicenter, open-label, randomized study evaluates the safety, tolerability, and antitumor activity of durvalumab and tremelimumab each as monotherapy (20 and 10 mg/kg Q4W, respectively) and in combination (20 and 1 mg/kg Q4W, respectively) in patients with unrese...


Abstract Objective  A nationwide measles–rubella (MR) vaccination campaign was executed in Pakistan in November 2021. Despite that, there was a persistence of new measles cases. Thus, we designed this study to determine the measles vaccination status in patients with measles and to determine the reasons of missed vaccination during the campaign. Methods  We reviewed medical records of measles patients >1 month to 12 years of age, presenting to the pediatric emergency of a tertiary care hospital of Karachi, Pakistan, during January to June 2022. We recorded patients' demographics and vaccination status. Measles patients who were hospitalized were reviewed to see if the child has or has not received vaccination during the MR campaign and what were the reasons for missed vaccination. Results  A total of 1,058 children presented with measles out of which 52.9% were male. The mean age of the patients was 2.2 years. Excluding 24.3% of the patients because of age <9 months, 800 (75.6%) patients were eligible for measles vaccine. Out of these, 80% received the vaccine (94.6% had one dose and only 5.3% had two doses). Among the 98 admitted patients, 68 (69.3%) were eligible for vaccination during the MR campaign, out of which 88.2% did not get the vaccine. Common reasons of missed vaccination were: lack of knowledge of the campaign (36.6%), impossibility to find vaccination facility (23.3%), and lack of trust in vaccines (15%). Conclusion  Most of the hospitalized measles patients had missed the vaccine during the MR campaign, mostly because of lack of knowledge of the campaign. This calls for devising strategies to improve coverage of vaccination services.


In this paper, we consider to seek vulnerabilities and we conduct possible attacks on the crucial and essential parts of Android OSs architecture including the framework and the Android kernel layers. As a regard, we explain the Binder component of Android OS from security point of view. Then, we demonstrate how to penetrate into the Binder and control data exchange mechanism in Android OS by proposing a kernel level attack model based on the hooking method. As a result, by implementing the attack model, it is illustrated that the Android processes are detectable and the data can be extracted from any process and system calls.


The arrangement of mortgage execution through Parate Executie in the Mortgage Act aims to provide convenience to creditors in the fulfillment of their receivables when the debtor is defaulted, i.e. the creditor can sell the object of mortgage right on his own power without having to go through the judiciary. However, the ease with which the creditors are in fact cannot be utilized due to differences in the interpretation of the regulation on execution parate in the Mortgage Act (Law No. 4 of 1996), the difference is increasingly tapered by the decision of the Supreme Court of the Republic of Indonesia Number 3210/K/Pdt/1984 which eliminates Bandung High Court Decision related to the case of Auction of Mortgage Objects through the absence of fiat from the Chairman of local District Court which also becomes a jurisprudence in the execution of mortgage objects. Based on this background, then the issues of discussion are about (1) what is the ratio decidendi of the Decree of MARI Number 3210/K/Pdt/1984 dated on 30 January 1986 which becomes the jurisprudence in the implementation of p arate e xecutie ? (2) what are the legal implications that may arise from the mortgage execution through p arate e xecutie with the availability of fiat courts, (3) how to arrange mortgage execution through the p arate executie in the near future? Beginning from the problems, they are further analyzed deeply by undertaking legal research. The approach used is legislation approach, concept approach, and both history and case approaches. The results of the research indicate that the ratio decidendi of the Decision of MARI Number 3210/K/Pdt/1984 dated on 30 January 1986 which becomes the jurisprudence in the execution of parate executie is the procedure of mortgage execution as the basis of mortgage execution. This does not mean that the procedure of this mortgage execution could be applied to all mortgage executions, including execution under Article 6 of Liability Law. This applies specifically for execution on execution title contained in the Certificate of Mortgage as referred to in Article 14 paragraph (2) of Liability Law. Legal implications may arise from the execution of mortality rights through parate execution with fiat courts if it does not undergo through the District Court and the debtor is not willing to empty the object of auction. Thus, the Head of District Court is not justified to execute the emptying and to declare execution parate directly to the office Auction without going through the fiat of the Head of the District Court. This is considered an unlawful act. The opinion of judges in this matter raises the legal uncertainty so that the author gives an alternative concept related to the arrangement of mortgage execution through parate executie. In the future, this Circular Letter of the Supreme Court must be declared null and void as opposed to the Mortgage Act based on the principle of lex superiori derogat lex inferiori . Besides, to provide protection for the parties, especially the debtor, creditor and third party (winning bidder), it is necessary to make a regulation concerning the law of a fair and lawful auction. Keywords: Mortgage, Mortgage Act, Liability Law


: Keraton Kanoman Cirebon has preserved a lot of priceless authentic cultural assets that are displayed in public area and Ruang Ndalem Keraton. One of the artefacts is a mythological figure called Paksi Naga Liman represents the great value of the teachings and wisdom which are respected and inherited by all the members of Keraton Kanoman Cirebon and its people. This mythological figure is chosen due to uniqueness and the fact that it can only be found in Keraton Kanoman. Besides, it represents an artwork having the hybridity of the acculturation of Islam, China, and Hindu (through the figures of the bird/ paksi / burok , a dragon, and an elephant respectively). This research aims to describe (1) the visualization concept, (2) the spiritual value, and (3) the implementation on contemporary arts and designs. The research method used is descriptive qualitative and the data are collected through library research, historical review, observation, and interviews. The results show that the visual concept of Paksi Naga Liman is the expression of guide spirituality to human relationships horizontally (immanent) and vertically (transcendental) through space and time. The spiritual value is shown by the cultural wealth appreciation which continuously inspires contemporary arts and designs to this day.


In this paper, we analyze the point spread function of optical scanning holography (OSH) system based on random phase encoding (RPE-OSH) with restricted pupils and compare the lateral resolution of RPE-OSH system with the one of conventional OSH system by the definition of Rayleigh criterion. The results show that the main lobe width of RPE-OSH system is much narrower than that of the conventional OSH system under the same conditions; thus, the reconstructed image in RPE-OSH system has a higher lateral resolution and reserves more detailed information. This conclusion is verified by numerical simulations of the Cymbella cymbiformis image reconstruction.


Using non-alkoxide V_2O_5 as precursors, benzyl alcohol and iso-butanol as solvents, V_2O_5 thin films were prepared by the sol-gel technique. In this paper, the thermal decomposition and crystallization process of V_2O_5 gel powders has been characterized with DTA-TG analysis. The structural properties of V_2O_5 thin films were analysed by using X-ray diffraction (XRD), Fourier transformation infrared spectrum (FT-IR). The transmittance spectrum, resistance vs. working temperature (R-T) relation, Voltage-current (V-I) relation and gas sensing properties concerning about V_2O_5 thin films have been also studied. Experimental results illustrated that the transmittance of V_2O_5 thin film increases with the increase of annealing temperature. V_2O_5 thin film has good sensitivity toward NO_x gas at room temperature.


Simple Summary This first systematic review and meta-analysis on the prevalence of nasopharyngeal carcinoma in patients suffering dermatomyositis was necessitated by the absence of a true and reliable prevalence estimate necessary to adequately inform medical preparedness and decisions. Following a careful review of literature and data analyses, a prevalence of 3.3% was found. It is hoped that a clear knowledge of the actual prevalence of nasopharyngeal carcinoma in dermatomyositis patients would not only help sensitize clinicians and patients about the frequency of these disease conditions but would also enhance the adoption of precautions essential to mitigate their co-occurrence in patients. Abstract For more than 50 years, nasopharyngeal carcinoma (NPC) has been associated with dermatomyositis (DM), a rare idiopathic inflammatory disorder that mainly affects the skin and muscles. Although the association between these rare diseases is well-documented, the actual prevalence of NPC in DM patients remains unknown. Here, a systematic review and meta-analysis of published data was conducted in accordance with the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). Electronic databases including PubMed, Scopus, ScienceDirect, and Google Scholar were searched without year or language restrictions for studies reporting the occurrence of NPC in DM patients. The study protocol was lodged with PROSPERO (CRD42021225335). A total of 95 studies covering 303 cases of NPC among 16,010 DM patients was included. Summary estimates were calculated using the random-effects model. The pooled prevalence of NPC in DM was 3.3% (95% CI, 2.5–4.3). When stratified according to study location, higher prevalence estimates were obtained for Hong Kong (36.5%), Malaysia (27.7%), and Singapore (11.9%). There was a predominance of cases among male DM patients compared with females, and most patients were aged 40 and above. Many of the NPC cases were found to be diagnosed after the diagnosis of DM. It is therefore pertinent to screen for NPC in DM patients, especially among older DM patients in the Asian region.


A novel method is proposed to address the issue of low-observability in Distribution System State Estimation (DSSE). We first use the historical data at the unobservable locations to construct and train proper Generative Adversarial Network (GAN) models to compensate for lack of direct real-time measurements. We then integrate the trained GAN models, together with the direct synchronized measurements at the observable locations, into the formulation of the DSSE problem. In this regard, we simultaneously take advantage of the forecasting capabilities of the GAN models, the available real-time synchronized measurements, and the DSSE formulations based on physical laws in the power system. As a result, on one hand we conduct a physics-conditioned estimation of the unknown power injections at the unobservable locations; and on the other hand, we also achieve a complete DSSE solution for the understudy low-observable active power distribution system.


Using hybrid Monte Carlo as well as molecular dynamics simulation, we study the nucleation and growth of nanoparticles from a supercooled liquid of Au at ambient pressure. We simulate the nucleation step using an umbrella sampling scheme in the course of hybrid Monte Carlo simulations. We then monitor the subsequent growth of the critical nuclei so obtained. In particular, we carefully determine the growth kinetics as well as the molecular mechanisms underlying the growth step. Our results establish the following crystallization pathway. In the early stages of the nucleation process, the structure of the nucleus is dominated by the stable face-centered cubic polymorph. Then, when the size of the Au nucleus is close to the critical size, the metastable hexagonal close-packed polymorph nucleates heterogeneously (or cross-nucleates) on the surface of the nucleus. The growth of the crystallite proceeds through successive cross-nucleations between the two polymorphs. A detailed analysis of the kinetics of grow...


An experiment was conducted to test the effects of biased versus unbiased peer input on the revised judgments of others. After completing a set of knowledge items and assessing their confidence in each answer, subjects were: (a) given written input (in the form of answers and confidence assessments) from a peer who had completed the same set of items, and (b) allowed to revise their earlier answers and confidence assessments. Peer input was either overconfident, underconfident, or appropriately confident. Relative to appropriately confident input, both overconfident and underconfident input caused subjects' accuracy in judgment to suffer. Overconfident input was particularly harmful because it led to more extreme overconfidence without any increase in accuracy. Practical implications of these results are discussed.


The study was conducted to know and compare the antibacterial activity of the ethanolic extracts of P h logacanthus thyrsifloru s (EEPT) , Hottuynia cordata (EEHC) , Curcuma caesia (EECC) and Syzygium jumbos (EESJ) on Staphylococ cus aureus, Escherichia coli and Pseudomonas aeruginosa by disc diffusion method. The ethanolic plant extracts were prepared from the bark of Syzygium jumbos and leaves of Phlogacanthus thyrsiflorus, Hottuynia cordata and Curcuma caesia by percolation method. Clinical isolates of Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa were obtained from the Department of Microbiology, Assam Medical College & Hospital. Disc diffusion method for antimicrobial susceptibility testing was performed acc ording to the standard Kirby Ba u e r method. The whatmann - 1 filter paper discs of 6mm sizes impregnated with the plant extracts were placed on Mueller - Hinton agar plates seeded with bacterial cultures of 0.5 Mc Farland standards. Ciprofloxacin (5μg/disc) was used as positive control. The antibacterial activities were assessed by the presence or absence of inhibition zones after incubating the plates at 37 0 c for 24 hours. The ethanolic extracts of Phlogacanthus thyrsiflorus (EEPT) and Hottuynia cordata (EEHC) showed significant anti - bacterial activity against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. Ethanolic extracts of Syzygium jumbos (EESJ) showed significant activity against Staphylococcus aureus and Escherichia coli while ethanolic extracts of Curcuma caesia (EECC) showed signifi cant anti - bacterial activity aga inst Staphylococcus aureus . Maximum zones of inhibition to Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa were exhibited by Phlogacanthus thyrsiflorus , Syzygium jumbos and Phlogacanthus thyrsiflorus respectively .


Abstract : The Air Force is intensifying its reliance upon flight simulators to provide initial and proficiency training for various aircrew members. The effectiveness of these simulators depends heavily upon the Defense Mapping Agency's digital cartographic data, which is used as source data to generate simulator data bases for visual, radar, and sensor simulations. Unfortunately, the source data occasionally displays certain characteristics which disrupt the highly automated processes used to generate these simulator data bases, or which lead to improper or visually distracting effects in the resulting simulations. This paper describes the development of a software package designed to detect these problems in the source data. The capability is also provided to interactively, or in some cases automatically, correct the problems, thus producing slightly modified data that is free of these disruptive characteristics. This software streamlines the simulator data base generation process and ultimately results in a higher fidelity simulator data base. (Author)


DISCLAIMER This report was prepared under an interagency agreement between the Minerals Management Service (MMS) and the National Marine Fisheries Service. This report has been technically reviewed by the MMS, and it has been approved for publication. Approval does not signify that the contents necessarily reflect the views and policies of the MMS, nor does mention of trade names or commercial products constitute endorsement or recommendation for use. It is, however, exempt from review and compliance with the MMS editorial standards. ACKNOWLEDGMENTS Thanks are extended to and the crew of the R/V Delaware who were essential to the collection and integration of these data. The National Marine Fisheries Service (NMFS) is required to produce stock assessments for all marine mammal stocks within the U.S. Exclusive Economic Zone. The Minerals Management Service (MMS) is evaluating potential environmental impacts of offshore oil and gas activities on marine mammals. Both agencies have a need for similar information on sperm whales and this is the basis for the cooperative research outlined here. This study, conducted in July 2003, has started a baseline of line-transect, photo-identification, oceanographic and genetic data for the Atlantic sperm whale. Compared with the Delta region in the Gulf of Mexico, parts of the Atlantic Ocean may serve as a control population of sperm whales with little exposure to sounds of oil and gas related activities. A total of 12 sperm whales were tagged during the four-week, July 2003 cruise yielding a substantial data set spanning both deep foraging and socializing from 9 of the 12 tagged animals. These tag recordings represent the first acquisition of sound and movement data from sperm whales in the North Atlantic. Visual and acoustic surveys were performed whenever weather permitted throughout the cruise and visual focal follows were made when tags were deployed. Complimentary data products included physical oceanographic measurements and skin and fecal samples from tagged and neighboring whales. The tag data set from the cruise has been examined using techniques developed on the Sperm Whale Seismic Study (SWSS) program to parameterize foraging and social behaviors. The data set has also been integrated into a combined data set covering the Gulf of Mexico, North Atlantic and Mediterranean seas to enable comparative analyses. We found that the North Atlantic whales follow a foraging and socializing cycle similar to the Gulf of Mexico whales but dive significantly deeper to forage. Foraging largely occurs at 500-1,100 m …


The main objective of this research is to investigate the triadic relationship among celebrity worship, self-brand connection and brand equity. Specifically, it aims to investigate the role of self-brand connections as a mediating variable in the relationship between celebrity worship and brand equity. The results of the conditional process analysis revealed that celebrity worship influences brand equity through direct as well as indirect pathways. It reveals that there is a direct and positive influence of celebrity worship on brand equity. It also finds that the consumer self-brand connection mediated the effect of celebrity worship on brand equity, extending support for the indirect influence on brand equity enrichment. The findings of the study offer key insights for academicians and marketing practitioners. It is one of the pioneering studies in the field of celebrity worship which helps academicians decipher the impact of celebrity as idols on the endorsed brand equity. Brand managers can use the findings for targeting niche consumer segments who are celebrity worshippers as they are more likely to remain loyal to the brand. They can also benefit from developing relationships with consumers as these may transform into long-lasting benefits for the brand.


JULY 2023 | VOL. 66 | NO. 7 | COMMUNICATIONS OF THE ACM 77 I M A G E B Y C K A /S H U T T E R S T O C K high throughput, and high availability. Hence, it is necessary to transform these scripts into performance-optimized code (for example, using C++) that can be developed by an engineering team with system and production knowledge. This transformation process is time-consuming and requires significant development, deployment, and double system maintenance efforts. Moreover, the big gap in the software stacks, personnel domain knowledge, and performance concerns may cause the challenging feature inconsistency problem; for example, different interpretations of window boundary (that is, inclusive or exclusive), variations in handling empty values, or diverse operator definitions. As an example, consider fraud detection where the features include "account balance" and its lenges, new design methodologies and systems are necessary to eliminate the added cost of consistency verification and ensure low latency in on-demand feature computing. In this article, we discuss the design principles and practices of tackling the challenges of realtime feature computing. Basically, we propose that such a feature computing platform should consist of three major components— a batch engine for offline training; a real-time engine for online serving; and a unified execution plan generator—to bridge those two engines to inherently guarstandard deviation (std). During offline training, the model may use yesterday's account balance while in online serving, the model is provided with the current account balance.1 Moreover, the std logic may also differ, as shown in the figure. These variations in data definition and computing can result in significant differences in prediction outcomes (that is, training-serving skew). Consequently, data scientists and engineers must invest significant effort in iterative development and cooperative consistency verification to align the results. To resolve these chalR EAL-TIME FEATURE


Mycobacteria from the Mycobacterium avium complex (MAC) cause a variety of diseases in‐ cluding tuberculosis-like disease in humans and birds, disseminated infections in AIDS pa‐ tients and otherwise immunocompromised patients, lymphadenitis in humans and mammals and paratuberculosis in ruminants. M. avium subsp. paratuberculosis (Map) is the etiologic agent of Johne ́s disease in cattle and it has been identified in human patients with Crohn's disease. The MAC comprises slow growing mycobacteria that are ubiquitous in the environment (soil and water), and have a wide source range, causing disease in various do‐ mestic and wild mammals and birds [1].


We prove that, on a smooth threefold, pseudoeffective divisors with closed and one-dimensional diminished base locus have birationally a Fujita-Zariski decomposition.


Factors such as post-develop hydrophobicity, polymer aggregation and acid diffusion length are driving forces in the formation of micro bridging defects. In this report, solutions for each possible cause are proposed and tested. It is proven that micro-bridging levels can be significantly reduced through a multi-tiered approach.


The appointment of 30 new peers to our unreformed House of Lords was announced this week. In the 2012 audit of UK democracy, Stuart Wilks-Heeg, Andrew Blick, and Stephen Crone discussed the composition and role of the upper chamber. They highlighted how the UK is almost unique among established democracies in possessing a parliamentary chamber that is mainly unelected, and set out particular concerns about the lack of accountability of government ministers sitting in the Lords.


With the development of electronic technology,the frequency of product quality as an important basis,which allows us to the requirements of crystal growing.If we only by the frequency of high-frequency oscillator sources can be very easy to get rich frequency.Frequence divider digital system is one of the basic design of the circuit,the paper introduced by Quartus development platform,using Verilog HDL design to achieve a duty cycle of arbitrary,and so even the frequency,duty cycle,such as arbitrary odd-frequency And the arbitrary duty cycle ranging from a half-integer frequency of the more common crossover,and through QuartusII a functional simulation.


H ISTORIANS have repeatedly stressed the importance of the additional army as a key political issue during the presidency of John Adams. John Quincy Adams first emphasized the army controversy as the most significant issue in the President's split with his cabinet and the eventual split in the Federalist party. More recently, historians such as Manning Dauer, Stephen Kurtz, and Alexander DeConde echoed this claim, varying only in detail. They all portrayed Adams as a moderate who supported a strong navy but had little desire for an enlarged army. In contrast, they depicted Alexander Hamilton and the high Federalists as dangerous extremists who desired a standing army, not only to oppose French aggression, but also to subdue the Jeffersonians. Kurtz placed the most emphasis on this matter, arguing that the army issue was of greater significance than the well-known Alien and Sedition Acts. Both Kurtz and Dauer also believed that Henry Adams correctly asserted that the extreme Federalists had every intention of using an enlarged army to crush democracy by force.I While historians have attempted to explore the issue, they have faltered on a more basic level. It is paradoxical that in spite of several analyses of the army as an issue, few historians have adequately defined and described the actual military forces of the Quasi-War. In particular, they have used the terms "additional army" and "provisional army" incorrectly. Part of the problem can be traced to the confusing use of the


In ordo. to establish cataloging procedures for non-book materials(NBM), library has In make policy decisions which will apply to all materials. This study explores problem areas in bibliographic control and descriptive cataloging for NBM and issues to be decided in cataloging policy for NBM are presented. Recently proposed KORMARC Rules for Descriptive Cataloging, NBM is looked into and compared with AACR2R and some problems to be considered for revising are suggested. Principle and tools needed for subject analysis of NBM are discussed and special issues of subject analysis for NBM are presented.


BackgroundPrevious studies have reported conflicting results concerning the influence of age and gender on the pharmacokinetics and pharmacodynamics of fentanyl, alfentanil, and sufentanil. The aim of this study was to determine the influence of age and gender on the pharmacokinetics and pharmacodyn


Ensuring security and privacy within the Grid computing environment is a fundamental and key requirement for users in order to adopt and use secure and trusted Grids. In light of this fact, the majority of grids, nowadays, provide security services by relying on the de facto standard GSI framework which makes use of Public key End Entity Certificates (EEC) and Proxy Certificates as its foundation. But, due to the huge burden in managing, distributing and revoking compromised EEC, Public Key Certificates are becoming an impediment to the wide adoption and use of Grids at scale. Thus, many research efforts stressed how compelling is the adoption of Identity-Based cryptography and Certificateless Public Key Cryptography within the Grid-Computing environment, which could alleviate the burden of using PKI certificates while, still, providing the intended secure, flexible and easy use of the Grid to both non expert users and Grid's administrators.
 In this paper, we propose a new Certificateless Identity-Based Proxy Signature scheme, for the grid environment, in order to enable attribute-based authorization, fine-grained delegation and enhanced delegation chain establishment and validation, all without relying on any kind of PKI Certificates or proxy certificates.


The title compound, C7H10N2O3, is planar and the structure is stabilized by an intramolecular N-H...O hydrogen bond. The molecules form dimers through N-H...O hydrogen bonds that are linked by N-H...N hydrogen bonds along the c axis.


During the mid to late 19th century, the New Zealand Legislative Council played an integral role in New Zealand's constitutional framework. One of the Council's most productive periods was during the 1860s. This paper analyses the Legislative Council by looking closely at the actions of one councillor, James Prendergast. The role of Attorney-General Prendergast in the Council during the 1860s provides insights into many of the important issues of the time including the New Zealand wars, Maori representation in Parliament, the debate over the provinces and the regulation of the legal profession. Studying Prendergast also highlights the fierce political rivalries of the time. Prendergast was an able councillor at a time when the Council provided a check on the power of the House of Representatives and acted as an influential forum for the discussion of major national issues.


The efficiency and loss maps represent an important tool to evaluate an electrical motor drive. The efficiency maps are usually computed using finite element analysis or equivalent circuits that take into account the motor losses. However, these methods need to be compared with efficiency maps that must be experimentally obtained using calibrated instruments. The main problem is how to implement an automated procedure that must obtain the motor or drive efficiency for all operating points. This paper describes an efficiency and loss mapping procedure that has been applied for a 5.3 kW three-phase internal permanent magnet machine prototype for traction applications, but it can be used for any AC machine with inverter supply. All measurements have been performed with an advanced data recorder instrument. The efficiency and loss maps are calculated after the test with a post-processing procedure that can provide all information regarding the motor exploitation, including current, voltage and flux vector trajectories in (d, q) rotor frame.


Due to the lack of natural occurring plasmids in higher eukaryotes, most vectors currently used for the modification of mammalian cells and organisms are based on modified viruses. But the use of these virus-based vectors still has severe safety risks and therefore considerable efforts are made to design alternative vector systems, whose function are based on chromosomal elements and which behave as an autonomous unit in the cell. The construction of episomal vectors was hindered by our limited knowledge of the epigenetic regulation of replication in higher eukaryotes. However, in the late 1990, a prototype non-viral episomal vector was constructed which replicates autonomously in all mammalian cells and is mitotically stable in the absence of selection. Its function relies on an expression unit linked to a scaffold/matrix-attached region (S/MAR). In this short review, we describe the rational of its construction and functioning. The prototype vector was improved within the past years with respect to establishment and expression efficiency and has now been tested for various preclinical applications. Eventually, S/MAR-based vectors will be improved to such a stage that they can provide a safe alternative to viral vectors to be used in gene therapy.


We report nonlinear conical diffraction in the superhoneycomb lattice, which is an edge-centered honeycomb lattice, induced in a photorefractive crystal. This system is of special interest, as it represents a hybrid fermionic – bosonic physical system. When nonlinearity is imposed, conical diffraction from a fermionic Dirac cone will change from circular diffraction rings, formed by small hexagons, into a triangular arrangement of hexagons. But from the bosonic Dirac cone, conical diffraction changes into elliptic diffraction rings of different inner symmetries, with the outer ring intensity damped.


The present study attempts with the objective to provide the current status of the bryophyte genus Bryum Hedw., in Rajasthan. A total of 15 taxa of Bryum belonging to Bryophyta have been investigated from various localities of Rajasthan, among these B. pseudotriquetrum var. subrotundum and B. thomsonii are new additions to the bryoflora of this state. It is observed that terricolous and saxicolous forms are the most dominant in the area.


The influence of the most toxic of methyl derivatives of tin thrimethyltin chloride (СH3)3SnCl on hemin catalase activity, was studied. Hemin is a catalytic centre of important hemproteids. It is established that the addition of this toxicant decreases the efficiency of hemin catalysis of hydrogen peroxide decomposition reaction in the alkaline media. Thereby, the toxic action of thrimethyltin chloride on hemproteids of antioxidative protection of fermentative section can be caused by their action on unprotein part of these important proteins, and it promotes the development of antioxidative stress in a living organism.


Starting from a random-matrix model, we construct the low-energy effective-field theory for the noninteracting gas of quasiparticles of a disordered superconductor in the mixed state. The theory is a nonlinear s model, with the order-parameter field being a supermatrix whose form is determined solely on symmetry grounds. The weak-localization correction to the field-axis thermal conductivity is computed for a dilute array of s-wave vortices near the lower critical field Hc1 . We propose that weak-localization effects, cut off at low temperatures by the Zeeman splitting, are responsible for the field dependence of the thermal conductivity seen in recent high-Tc experiments by Aubin et al. @S0163-1829~99!08205-3#


ABSTRACT In this article, I investigate how Shadi Angelina Bazeghi writes about the Iran-Iraq War in her poetry collection Flowmatic (2020). Bazeghi assembles several different kinds of texts in Flowmatic, and one of these texts is a testimony by an Iranian soldier-engineer who worked as a programmer setting up at system to identify the bodies and body parts of fallen Iranian soldiers. Both the words of the soldier's testimony and the act of programming and data processing have found their way into the poem; as appropriated text and as the poem's overarching aesthetic mode. Using the soldier's witness account as a prism, I will look at three aspects of the poetry collection: 1) how the testimony is appropriated, 2) how Bazeghi is witnessing though appropriation, and 3) how she writes about war from a feminine point of view. I argue that Bazeghi through the evasive aesthetics and the heightened appropriation in Flowmatic challenges how women can witness and write about war.


New scientific knowledge is no longer merely the key to unlocking the secrets of nature and society. It now represents the "becoming" of a new world. Scientific developments affect the ways in which we conduct our affairs, as well as how we comprehend the changes underway as the result of novel technical artefacts and scientific knowledge. The practical fruits of biotechnology are a case in point; they have grasped our imaginations, and generated worldwide debate and concern. Debates on biotechnology shift between images of utopia and dystopia. The social sciences deserve a voice in the debate, and can do so through sober examination of the economic, social, and cultural implications of biotechnology. Some economists even predict that the importance of biotechnology as the technology of the future will far exceed that of the information technologies, in particular the Internet. The contributors to this volume are drawn from a broad spectrum of the social sciences, and include Nico Stehr, Gene Rosa, Steve Fuller, Steve Best and Douglas Kellner, Nikolas Rose, Fred Buttel, Javier Lezaun, Anne Kerr, Susanna Hornig Priest and Toby Ten Eyck, Martin Schulte, Alexander Somek, Steven P. Vallas, Daniel Lee Kleinman, Abby Kinchy and Raul Necochea, Herbert Gottweis, J. Rogers Hollingsworth, Gisli Palsson, Elizabeth Ettore, Richard Hindmarch and Reiner Grundmann. The impact of science on society is destined to be a fundamental concern in the new century. This volume illustrates the contributions anthropology, law, political science, and sociology can make to the ongoing discussions about the role of biotechnology in modern societies.


The title of this paper proclaims its central interest—the relationship which holds between the concept of integrity and the concept of the identity of the self, or, for short, self-identity. Unreflective speech often suggests a close relationship between the two, but in the latter half of this century, notwithstanding one or two notable exceptions, they have been discussed with minimum cross-reference as if they belonged to two rather different philosophical menus which tended not to be available at the same restaurant on the same night. My intention is to argue that our account of the one carried implications for the other and that this relationship is reflexive. My argument will proceed by stating and criticizing a common account of the relationship between each of these concepts which tends to offer mutual support for the implied account of each. Thereafter an alternative account will be outlined.


Spirogyra neglecta (Hassall) Kützing is an edible freshwater macroalga. It is available and consumed as local food in Thailand, especially in the northern and northeastern parts. To ascertain its good benefit for health and safe for consumption, this study was, therefore carried out to determine the phytochemical compositions, nutritional contents, cytotoxicity, and anti-inflammatory activity of the different extracts from S. neglecta. The extracts were prepared by using different solvents, such as propylene glycol, methanol, and ethanol solutions. GC-MS analysis revealed the presence of 30, 39 and 36 phytochemical compounds in propylene glycol, methanol, and ethanol extracts, respectively. Phytol, which has been reported to have anti-inflammatory activity, was one of the predominant compositions in the extracts. The extracts contained high nutritional contents of protein, lipid, fiber, ash, moisture, and carbohydrate up to 21.68 ± 4.52, 3.53 ± 0.23, 14.77 ± 0.89, 10.73 ± 0.47, 9.79 ± 0.11 and 47.36 ± 3.89 %, respectively. The highest total protein was found in propylene glycol extract. The highest total lipid was in ethanol extract. Meanwhile, the highest fiber, ash and total carbohydrate were in methanol extract. In addition, all the extracts possess relatively low cytotoxicity, with IC50 values greater than 1,000 µg/mL. The extracts 1,000 µg/mL exhibited anti-inflammatory activity via inhibition Nitric oxide (NO) production by 29.87 ± 1.56 to 55.17 ± 1.91 %. The propylene glycol extracts from S. neglecta showed the highest inhibitory activity on NO production compared to others.
The overall results indicating the propylene glycol is the solvent that produces the best extraction performance.  The extracts from S. neglecta exhibit anti-inflammatory activity by inhibiting NO production.  The phytochemical compositions are partly responsible for anti-inflammatory activity of the extracts. The high nutritional contents complement relatively low toxic. Thus, S. neglecta can be used as benefit natural sources for food products, supplements, and medicinal plants.
HIGHLIGHTS

Using GC-MS analysis, there are 30, 39 and 36 phytochemical compounds in propylene glycol, methanol and ethanol extracts from Spirogyra neglecta, respectively
The extracts from neglecta possess high nutritional contents of protein, lipid, fiber, ash, moisture, and carbohydrate
The extracts from neglecta show relatively low toxic to the RAW 246.7 cells with LC50 >1,000 µg/mL, by MTT assay
The extracts from neglecta exhibit anti-inflammatory activity by inhibition of NO production. The propylene glycol extract displays the highest activity compared to others
The anti-inflammatory activity of the extracts is partially from Phytol

GRAPHICAL ABSTRACT


IN 2007 ALEX ROSS, the music critic for The New Yorker magazine, published an appreciative article on the Finnish composer Jean Sibelius, titled "Apparition in the Woods." Sibelius was one of the regional composers—along with Grieg, Dvořak, and Nielsen—who came from Europe's smaller nations. In one passage, Ross sought to indicate something of the remoteness of Sibelius's origins when he wrote that "Finns are strangers to the European family. Descendants of an errant Mongolian tribe, they speak a language unrelated to the Indo-European linguistic group." However, when that article reappeared as a chapter in The Rest Is Noise: Listening to the Twentieth Century, the passage was recast to read, "In a certain sense, Finns are strangers in the European family. Belonging to the Finno-Ugrian category, they speak a language largely unrelated to the Indo-European group." In this reworking of the passage, the idea that Finns stand apart from European culture is qualified twice, for now they are strangers only in "a certain sense" and the Finnish language is "largely unrelated" to the IndoEuropean languages, which implies that in some respects it is or at least might be related. Meanwhile, the "errant Mongolian tribe" has disappeared entirely. The reason that these editorial changes were made will not concern us here. Instead, we move back exactly one century earlier to a short-lived episode in a small mining community in northern Minnesota that has received attention in Finnish American historiography as well as in whiteness studies, particularly in David Roediger's Working toward Whiteness. On September 9, 1907, John Svan, a miner living and working in Eveleth, Minnesota, applied to become a naturalized citizen of the United States. Svan was born in Noormarkku, Finland, in 1874, and he had immigrated to


The pressure survey data in bottom hole were analyzed,and a computing method for annular cuttings effecting pressure increment in bottom hole was proposed.The responding calculation software was worked out.The analysis indicates that the actual annular cuttings in bottom hole have a great influence on the negative pressure at bottom.For deep wells of 40005000 meters in depth,when drilling rate is up to 10 meters per hour,the pressure increment in bottom hole resulted from annular cuttings is up to(34MPa) and even higher.In order to control the negative pressure,the influence of annular cuttings should be considered.For different situations,the different control methods should be adopted.This methodology was applied to under-balanced calculation and negative pressure control in bottom hole in Daqing Oilfield.The negative-pressure control for under-balanced drilling in Daqing Oilfield was improved.


The design of physical security measures is a specialized technical area that does not fall in the normal skill record and resume of commanders, architects, engineers, and project managers. This document provides guidance to those parties tasked with implementing existing and emerging physical protection system requirements: -    Creation of a single-source reference for the design and construction of physical security measures for high-risk personnel (HRP). -    Promulgation of multi-service standard recommendations and considerations. -    Potential increase of productivity of HRP and reduced temporary housing costs through clarification of considerations, guidance on planning, and provision of design solutions. -    Reduction of facility project costs. -    Better performance of modernized facilities, in terms of force protection, than original facilities. Throughout this process you must ensure: confidentiality, appropriate Public Relations, sustainability, compliance with all industrial guidelines and legal and regulatory requirement, constant review and revision to accommodate new circumstances or threats. Introduction Physical security is an extremely broad topic. It encompasses access control devices such as smart cards, air filtration and fireproofing. It is also heavily reliant on infrastructure. This means that many of the ideal physical security measures may not be economically or physically feasible for existing sites. Many businesses do not have the option of building their own facility from the ground up; thus physical security often must be integrated into an existing structure. This limits the overall set of security measures that can be installed. There is an aspect of physical security that is often overlooked; the humans that interact with it. Humans commit crime for a number of reasons. The document focuses on two building types: the HRP office and the HRP residence. HRP are personnel who are likely to be terrorist or criminal targets based on their grade, assignment, symbolic value, criticality, and threat and vulnerability assessment. Levels of protection The recommendations contained in this criterion are intended to minimize the possibility of HRP casualties in buildings or portions of buildings in which they work and live. These recommendations provide appropriate and implementable measures to establish a level of protection against terrorist attacks where no known threat of terrorist activity currently exists. While complete protection against all potential threats is cost prohibitive, the intent of these recommendations can be achieved through prudent master planning, real estate acquisition, and design and construction practices. Tag number The tag number at the beginning of each physical security measure (recommendation) is unique and is intended to be a communication aid when linking the requirement (recommendation) to the supporting text or commentary. The three-character tag number uses the following legend. Tag Number First Character -The first character is an abbreviation for the defense zone layer that is most applicable for the countermeasure. "S" is used to represent site or external zone issues. "P" is used to represent the perimeter zone. "G" is used to represent issues relative to the property grounds. "E" is used to represent issues associated with the building exterior of the HRP office or residence. "I" is used to represent issues associated with the building interior. "H" is used to represent issues associated with the safe room or safe haven. Tag Number Second Character - The second character is a sequential number for countermeasures in a given zone - a requirement or a recommendation. This number ensures a unique tag number. Tag Number Third Character- The third character indicates whether the countermeasure is applicable to offices, residences, or both (common). "O" indicates a requirement or recommendation unique to offices. "R" represents a requirement or recommendation to residences. "C" represents a common requirement or recommendation applicable to offices and residences. Alternate and equivalent means or methods While listed physical security measures may be very specific, the intent is to achieve a certain level of protection for the HRP. If a requirement can be met by alternate and equivalent means or methods, then that variance should be accepted when proven to provide the equivalent level of protection. Common recommendations The recommendations in this section apply to both HRP offices and residences - S-1C: Final Approach Routes, S-2C: HRP Vehicle Parking, S-3C: Response Forces, S-4C: DoD Compound, P-1C: Subterranean Openings, E-1C: Number of Levels, E-2C: Window Locks, E-3C: Minimize Number of Exterior Doors, E-4C: Exterior Door Material, E-5C: Door Swing, E-6C: Exterior Door Hinges, E-7C: Exterior Door Jambs, I-1C: Skylights, I-2C: Furniture Layout, H-1C: Safe Room/Haven. Office recommendations In addition to the common recommendations for HRP buildings, the following additional physical protection measures are recommended for HRP offices - S-5O: Minimum Standards, I-3O: Internal Controlled Access Area, I-4O: Primary Access Door, I-5O: Other Access Doors, I-6O: HRP Office Door Frame Construction, I-7O: Office Construction, I-8O: CCTV. Residence recommendations In addition to the common recommendations for both HRP buildings, additional physical protection measures are recommended for HRP residences. Many of the recommendations are based on the assumption that the HRP residence is not located on a military installation- S-6R: Neighborhood, S-7R: Building Appearance, S-8R: Commute Route, S-9R: Emergency Services, S-10R: Crime Area, S-11R: Vehicular Approaches, P-2R: Perimeter Boundary, P-3R: Egress Route Viewing, P-4R: Vehicle Access Points, P-5R: Perimeter CCTV, P-6R: Perimeter IDS, G-1R: Standoff Distance, G-2R: Vantage Points, G-3R: HRP POV Parking, G-4R: Security Lighting: Provide security lighting around the residential exterior, G-5R: Unobstructed Space, G-6R: Access Control Point, G-7R: Visitor Parking, E-8R: Exterior Door Locks, E-9R: Windows, E-10R: Under-building Access Control, E-11R: Roof Access, E-12R: Residential Mailbox Guidelines, E-13R: Trash Receptacles, I-9R: Fire Protection System, I-10R: Intrusion Detection System (IDS). Conclusion The challenge is twofold. The first challenge is to reach an agreement that something needs to be done. This involves altering mindsets, building consensus and getting senior management support. The second challenge is in developing and implementing an effective and tailor-made integrated physical security plan. This plan consists of three mutually supporting elements – physical security measures, operational procedures and policies. Physical security covers all the devices, technologies and specialist materials for perimeter, external and internal protection. This covers everything from sensors and closed-circuit television to barriers, lighting and access controls for HRP offices and residences. The following crucial elements must be taken into account – deterrence, detection, delay and response and then recovery and re-assessment. All are mitigation measures. These are the foundations on which any integrated physical security plan must be built.


The review is prepared on K. S. Bezik's school appliance «Contract Law». The importance of the chosen subject is explaind, many positive moments of author's made work are underlined, the conclusion, that this school appliance will be useful for students all forms of education in the programmes «Bachelor» and «Magistor» as well as during the studying such diciplines as «The Civil Law», «The Contract Law», «The problems of Contractt Law's conducting» is made. There is the conclusion of the recommendation of the book to it's publication.


A. INTRODUCTION (1) The Civilian inheritance (2) The maxims (3) The rationale (4) Other jurisdictions B. DEVELOPMENTS (1) Types of entitlements (2) Property affected (3) The parties benefited (a) Personality and capacity (b) Survivorship (i) Testate succession (ii) Statutory provision C. THE MAXIM PRO IAM NATO IN THE MODERN LAW (1) Third parties (2) Live birth (a) Interim protection (b) Practical problems D. THE OMITTED CHILD (1) Similarities between the conditio si testator sine liberis decesserit and the pro iam nato rule (a) Presumed intent of the testator (b) The option to revoke is personal to the child (c) The child must be born alive (2) Differences between the conditio si testator sine liberis decesserit and the pro iam nato rule E. MODERN TECHNOLOGY F. CONCLUSION


This research aims to study the effects of sympathy module and positive psychological capital on teacher's job satisfaction and happiness. The research was conducted to seek a way to improve quality of teacher's lives, precondition of education for teachers and students' happiness, with 249 teachers of public kindergartens, elementary schools, middle schools and high schools in Daejeon city. The data was collected based on questionnaires consisting of some scales such as sympathy module, psychological capital, job satisfaction and happiness. In statistical analysis, reliability and validity on that scale were conducted through internal consistency coefficient and factor analysis, the relationship among 4 scales was found through correlation analysis and the difference between their job satisfaction and happiness by sympathy module and psychological capitals was seen by performing the two-way analysis of variance (ANOVA). The research result shows that hypothesis Ⅰ'teacher group with affective sympathetic module has more job satisfaction than that group with reasonable sympathetic module' and hypothesis Ⅱ 'teacher group with higher levels of psychological capital has more job satisfaction than that group with lower levels of one' were supported. However, the result indicated that hypothesis Ⅲ 'teacher group with affective sympathetic module and higher levels of psychological capital has more job satisfaction than the other group was not supported. Furthermore, hypothesis Ⅳ'teacher group with affective sympathy module has higher level of happiness than that group with reasonable sympathetic module and hypothesis Ⅴ' teacher group with higher levels of psychological capital has more happiness than that group with lower one were supported. However, the result found that hypothesis Ⅵ 'teacher group with affective sympathetic module and higher levels of psychological capital has more happiness than the other group was not supported. The research result demonstrates that the more affective sympathetic module and improved psychological capital enables to increase teacher's job satisfaction and happiness in exchange and communication process. The result gives an opportunity to seek a variety of education and practical method for more effective sympathetic module and increased psy


In Spinoza, the passage from the state of nature to civil society is not represented in terms of a rupture or discontinuity. Socialization does not occur, as it does in Hobbes, by virtue of the intervention of a juridical order opposed to Nature and transcendent to the passional, conflicted field of presocial interests which it organizes. Thinking against the grain of seventeenth-century rationalism Spinoza avoids presenting man's passional nature as a difficulty to be overcome, regarding it instead as the very field of investigation upon which ethical and political theory must by founded. This naturalism is reflected in Spinoza's deviation from Hobbesian contractarianism: there is, for Spinoza, no mediation of a contract required to socialize 'anti-social' individuals, no total transfer of natural rights creating an obligation imposing itself as an external norm, no obligating force of command at the origin of social relations, and no rational break with the passional order of Nature: in short, there is in Spinoza very little evidence of Hobbes' 'antagonistic solution' to the problem of human sociability. This paper situates Spinoza's account of the transition to civil society within the framework of his conception of human nature and the role the affects and imagination play in shaping individuals and social relations. For Spinoza, this transition is a process continuous with the exercise and collective development of natural rights or powers, including the natural power of reason. Conceiving of civil society in this manner, Spinoza


The porous silicon tube structures, with a diameter of 20 μm, were formed by pulsed anodization process. A phenomenological mechanical model was used to explain the formation mechanism. The agreement between the experimental data and theoretical results indicated that the stresses in parallel and perpendicular directions of the nanocolumnar structure may cause the crack and curve of the porous silicon layer to form the tube structures.


Human–object interaction (HOI) is a human-centered object detection task that aims to identify the interactions between persons and objects in an image. Previous end-to-end methods have used the attention mechanism of a transformer to spontaneously identify the associations between persons and objects in an image, which effectively improved detection accuracy; however, a transformer can increase computational demands and slow down detection processes. In addition, the end-to-end method can result in asymmetry between foreground and background information. The foreground data may be significantly less than the background data, while the latter consumes more computational resources without significantly improving detection accuracy. Therefore, we proposed an input-controlled transformer, "ratio-transformer" to solve an HOI task, which could not only limit the amount of information in the input transformer by setting a sampling ratio, but also significantly reduced the computational demands while ensuring detection accuracy. The ratio-transformer consisted of a sampling module and a transformer network. The sampling module divided the input feature map into foreground versus background features. The irrelevant background features were a pooling sampler, which were then fused with the foreground features as input data for the transformer. As a result, the valid data input into the Transformer network remained constant, while irrelevant information was significantly reduced, which maintained the foreground and background information symmetry. The proposed network was able to learn the feature information of the target itself and the association features between persons and objects so it could query to obtain the complete HOI interaction triplet. The experiments on the VCOCO dataset showed that the proposed method reduced the computational demand of the transformer by 57% without any loss of accuracy, as compared to other current HOI methods.


The Computer Agents Teaching Helping Interactions Effectively (CATHIE) training system is a distance training environment for entry-level human service professionals. A brief discussion of the theoretical motivations behind the CATHIE system design is given. Seeing an animated pedagogical agent synchronized to recorded dialog, the trainee interaction resembles a face-to-face counseling session. The training exercise is defined by a structured script where each step includes agent dialog, a set of choices, and choice feedback. To support distance training, CATHIE is a web-based application and its implementation is described in detail. Furthermore, the script structure enabled the implementation of CATHIE in a generic fashion, independent of the script content. The system tracks user responses, time to respond with learning measured by comparing the differences between pre and posttest results.


This paper studies information structures in a fuzzy β-covering information system. We introduce the concepts of a fuzzy β-covering information system and homomorphism between them, and investigate related properties. The concept of information structure of a fuzzy β-covering information system is given. We discuss the relationships between information structures from the view of dependence and separation. Then granularity measures for a fuzzy β-covering information system are studied. Finally, we discuss invariance of fuzzy β-covering information systems under homomorphism and illustrate its application on data compression.


.This paper gives manimax value of generalized eigenvalue of real symmetric matrix with general-ized Rayleigh quotient,and extends the conclusion to Hermite-matrix,and gets region of existing maximum(mini-mum) value of Hermite-matrix.


Although internalized stigma is associated with negative outcomes among those with prolonged psychosis, surprisingly little work has focused on when in the course of one's illness stigma is internalized and the impact of internalization on symptoms or social functioning over the course of the illness. Therefore, this study investigated whether (1) internalized stigma is greater among those later in the course of psychosis and (2) whether internalized stigma has a stronger negative relationship with social functioning or symptoms among those with prolonged compared to early phase psychosis.


This article is part of a research masters about continuing education of math teachers who work in computer classrooms in public schools in the state of Mato Grosso do Sul. In this article we analyze the possibility of learning of a teacher in training, to interact with another people in a virtual learning environment, based on the training model adopted. The analyze of data was developed from the written records made by teachers in the virtual learning environment. The theoretical framework is guided by studies Valente, on the approaches to distance education, and studies of Scherer, about featuring subjects in virtual learning environment as inhabitants, visitors and passersby. The research showed that the training model chosen, the high degree of interaction between subjects in the approach of virtual togetherness, the inhabitant attitude of teachers in training, enables learning in Distance Education mode for the use of digital technologies.


This article outlines the Center for Research and Education in Technology (CRET), West Virginia University School of Dentistry, Dr. W. Robert Biddington Center for Dental Innovation. This article discusses what technology, materials, and equipment have been utilized at the Biddington Center for Dental Innovation at West Virginia University School of Dentistry and includes anonymous student comments about their experience within the center.


Bernhardson (1966) is to be commended for working O L I ~ the preliminary steps to establish the formula to correct for guessing when the Three-decision test is used. When the Three-decision Multiple-choice Test was devised, it was not contemplated that obtained scores would be compared directly with formally established passing grades, such as 50% or 70%. Conversion to percentile or standard deviation as expressions of relative position is standard testing practice; with subsequent translation to letter grades, when required, a judgmental matter. Since the original article (Willey, 1960) was published, the Three-decision Multiple-choice Test has been adapted to IBM Portapunch Card recording. The upper tier of 40 5-option spaces is used for recording the choice believed to be correct; the lower tier for recording two choices believed to be incorrect. The test-scoring machine, the Gradomat, counts 0, 1, or 2 errors per item. In this use, scores yield about twice the range obtained with conventional scoring, extending from 0 errors to 48, which is the chance score for these conditions. Decile groupings are used in interpretation of these error scores to students, and these are ultimately converted to letter grades without recourse to formal percentage passing grades at any stage. Bernhardson's comments do not appear to be relevant to such standard treatment of test scores.


Nowadays, Global Navigation Satellite Systems (GNSS) and complementary positioning technologies are expanding, offering new resources to the localization process. Software Defined Radio (SDR) is emerging as an alternative to developing flexible and multi-technology solutions in a dynamic environment. This work describes the main operational signals in GNSS systems that can be used in a multi-constellation, multi-frequency receiver. Also, it proposes the reception of GNSS signals using a modular architecture based on SDR. The SDR GNSS receiver is confronted with two platforms operating as Front-Ends: ADALM-PLUTO and Ettus USRP X310 - UBX160. The results, corresponding to the capture of GPS signals in the L1 band, show the impact of the platform's performances in the satellite acquisition signal process.


In this essay I craft a procedure for evaluating claims of moral personhood that would allow us to answer ethical questions raised by issues like abortion, animal rights, artificial intelligence, etc. I focus specifically on the abortion debate as a case study for applying my procedure. I argue that our moral instincts have evolved to promote group cohesion, a necessary prerequisite of which is reliable identification of other group members. These are "persons" in the moral sense of the word. However, while our moral intuitions may be good at picking out paradigmatic instances of moral persons, peripheral or putative instances of this category are a matter of intense debate. Further, I show that the attempt to clarify the boundaries of moral personhood by appealing to physical traits—what I characterize as the equation of moral personhood with ontological personhood—does not actually resolve the underlying ambiguity, nor does it answer the moral question why we ought to recognize moral rights in the first place. I argue instead for a three pronged inquiry that asks (1) whether the entity in question is capable of articulating its own entitlement to moral consideration; (2) if not, whether recognizing it as a moral person would facilitate the recognition of more paradigmatic instances of moral persons, or whether the failure so to recognize it would impede the recognition of more paradigmatic instances of moral persons; and (3) whether the entity's moral personhood can be recognized without cancelling or substantially burdening the moral rights of paradigmatic instances of moral persons. I argue that, applying this test, abortion is morally permissible, at least in the early stages of pregnancy when the vast majority of abortions occur anyway.


Having already paid tribute to a Nobel Prize in Economics in these columns, our European journal could not contain its delight when, on October 15th, 2012, the Norwegian Academy awarded the Nobel Peace Price to the European Union. Jean Monnet said that nothing is done without men, but nothing lasts without institutions. Whether one is for or against the European Union, whether one approves or disapproves of the options it announces, whether one is impatient with or becomes alarmed by the slow...


Iodine deficiency has been shown to lead to adverse pregnancy and birth outcomes. This study examined the effect of early introduction of iodized salt on pregnancy and birth outcomes in a moderately iodine deficient area. Sixty randomly selected districts across six zones in the Amhara region of Ethiopia were randomly assigned to receive the intervention (early access to iodized salt) or serve as the control (later access through normal market forces). One village each in twenty‐two of the intervention districts and 22 of the control districts was randomly selected for data collection. A total of 1220 pregnant women who conceived after the intervention began were assessed for their iodine and iron status, and their household salt was tested for iodine. Additional data were collected on their household socio‐demographic status and iodized salt, gestational history, adverse pregnancy and birth outcomes, and child nutritional status 2 to 13 months old after mothers gave birth. The mothers had an average age of 28 ± 6 y with low education (77% illiteracy), low household assets (42% scored <3 out of 10), and poor water and sanitation (61%). The median maternal urinary iodine concentration was adequate and significantly higher in the intervention communities than that of the controls (163 vs 121 μg/L, p<0.0001). Additionally, fewer pregnant women (28% vs 41%, p<0.05) and their children (13% vs 20%, p=0.06) had urinary iodine less than 50 μg/L in the intervention than control communities. After accounting for the effect of cluster and gestational history, the intervention did not significantly reduce miscarriages (OR (95% CI): 2.5 (0.9, 6.9)), stillbirths (OR (95% Cl): 1.0 (0.4, 2.8)), or infant mortality (OR (95%CI): 0.9 (0.5, 1.6)). Our inability to detect an effect of early access to iodized salt on birth outcomes may be due to (i) higher than expected access to iodized salt among the controls, (ii) lower than expected prevalence of poor birth outcomes, and (iii) inadequate sample size. The intervention improved pregnant women's iodine status and governments should pursue universal salt iodization program for the multiple known benefits.


A study was conducted to evaluate the organic carbon and dissolved oxygen (DO) conditions of surface sediments and water samples and their effects on species diversity of the littoral macrofauna around the Rumueme Creek in the upper Bonny Estuary. Sediment, water and benthic samples were collected from five sampling stations for four months (August – November). Mean sediment organic carbon ranged from 2.67 ± 0.58 – 16.00 ± 5.00% and was significantly higher at the site (STN 4) under the influence of an abattoir compared to all other sites. Mean DO of surface water fell in the range 3.50 ± 0.50 – 6.50 ± 0.42 mg/l. Differences in mean DO were not significant between study sites, but periods. Significantly higher mean DO value was obtained in August and September than the other two months. Species diversity of littoral benthos was characteristically low across study sites, and ranged from 0.10 – 1.74. Both organic carbon and DO concentration were not found to be linearly related to species diversity. It was concluded that rather than sediment organic carbon and DO conditions, there may be other underlying environmental factors responsible for the low species diversity recorded.


Purpose to investigate discourse in Alzheimer's disease (AD) using a picture narrative task; to examine possible difficulties in the expression of knowledge and the relationship between discourse and cognition. Methods the design of the study was transversal, using quantitative comparison of groups. The clinical sample consisted of eighteen subjects with AD, eight of them with moderate cognitive decline (GDS 4) and ten with moderate-severe cognitive decline (GDS 5); the control group consisted of sixteen subjects without neurological or psychiatric disorders. All were matched for gender, native language, age and education and subjects underwent cognitive assessments. The discourse task consisted of a picture narrative of the tale "Little Red Riding Hood." Results participants with AD had lower overall coherence scores and more difficulties in the expression of knowledge than subjects without AD. Discourse deficits correlated with performance on cognitive measures. The GDS 4 and GDS 5 groups differed in local coherence scores. Conclusion discourse of subjects with AD was characterized by failure in coherence and informativeness, which related strongly with their cognitive deficits.


For calculating the risk of failure of an electric system due to switching overvoltage stresses, rules are needed for simulating field-generated overvoltages with laboratory-produced impulses. The present study deals with switching overvoltages that present two successive peaks and provides guidelines for estimating the response of air insulating gaps to such overvoltages.


Law is a set of regulations and rules of norms which is made by the state and judicially enforceable. The rule of law ideally provides both justice and order to individual as well as social stability. This article is aimed to highlight some particular circumstances on how people tend to justify obedience or disobedience in society and of the nation. This article is written and analyzed by using normative legal research methods. A strong legal system should consist of legal rights and obligations as two inseparable parts. It also discusses about two aspects of legal relationships, namely: (a) power or authority of rights, (b) legal obligations. Practically, law has given legal consequences in people's lives in terms of right and obligation so that people will act obediently and appropriately by following the legal norms. The right to obey and disobey a law is inherent in people as legal subjects. This circumstances will give both benefits and consequences as defined on the purpose of the law itself.


The simulation and statistical modeling are conducted using Silvaco TCAD tools and L9 orthogonal array (OA) of Taguchi method respectively to design a proposed layout of 10 nm gate length (Lg) Bilayer Graphene Field Effect Transistor (Bi-GFET). The investigated process parameters are halo implant dose. halo implant energy, source/drain (S/D) implant dose and source/drain (S/D) implant energy, while the noise factors are halo implant tilt angle and source/drain (S/D) implant tilt angle. The process parameters and the noise factors are optimized using the L9 orthogonal array (OA) of Taguchi method to achieve the highest possible ION/IOFF ratio. Utilizing both signal-to-noise ratio (SNR) and analysis of variance (ANOVA), the most dominant process parameters uponION/IOFF ratio are identified as S/D 1 International Journal of Pure and Applied Mathematics Volume 118 No. 24 2018 ISSN: 1314-3395 (on-line version) url: http://www.acadpubl.eu/hub/ Special Issue http://www.acadpubl.eu/hub/


The invention relates to a processing method of position holding information of a security account and an apparatus thereof. The method comprises the following steps that: (1), a server collects security research report data of all clients; (2), the server transmits the security research report data to a security research base database server; (3), the server carries out deviation processing on the security research report data that have been input into the database; (4), the server transmits the security research report data that has been processed by the deviation processing to a security research consistence expectation database server; (5), the server collects client position holding data of clients; (6), the server carries out matching one by one between the position holding data and data in the security research consistence expectation database server, and latest research data is screened from the security research consistence expectation database server; and (7), the server displays an analysis content of the position holding data in a listing mode. Compared with the prior art, the technology employed in the invention enables a research content aiming at a certain stock by combining information of all authority research institutions to be provided, so that advantages of research information of all authority research institutions can be combined and thus the research content can be utilized by an investor.


PQM is a powerful method to measure PO2 in microvessels. However, its application to stationary tissue and fluids has never been substantiated. Multiple flash excitations applied in PQM to the same sampled volume produce AOD and distort the measured PO2. The magnitude of the AOD is determined by the radius of the excitation area R and rate of excitation light pulses F. We have analyzed the performance of two types of instruments in order to explain reported paradoxical PO2 results and optimize PQM design. The combination of a large R and high F reduces PO2 in perivascular tissue to 64 % of the actual value, creating a large transmural PO2 drop previously interpreted as the result of a large O2 consumption by the vessel wall. The AOD also occurs in the smallest vessels due to their low blood velocity V. An instrument with a large R and F has a high critical velocity Vcr. When V in a vessel is low (V/Vcr < 0.1), PO2 is strongly underestimated. This artifact is responsible in part for the reported longitudinal PO2 gradients in arterioles, PO2 rise in venules and low PO2's in lymphatic microvessels. The PQM technique combining a small R with a low F prevents the AOD in flowing blood and lymph. Artifact‐free PO2 measurements in stationary tissues and fluids were achieved with the scanning excitation principle that excludes multiple excitation of the same sampled volume. Support: AHA‐0655449U and NIH‐HL18292.


The utility model discloses an automatic testing apparatus for a battery protective plate, comprising an automatic pressing-down mechanism and a protective plate testing mechanism, wherein the automatic pressing-down mechanism comprises a horizontal bottom plate, a vertical plate, a cylinder, and a travel switch, the vertical plate is fixedly connected with the horizontal bottom plate, the cylinder is mounted on the vertical plate, the travel switch is fixedly connected with the horizontal bottom plate, and the position of the travel switch is adaptive to a detection position; and the protective plate testing mechanism comprises a probe, a probe support, a protective plate carrying seat and pressing blocks, the probe support is fixedly connected with the cylinder rod of the cylinder, the probe is mounted on the probe support, both sides of the protective plate carrying seat are respectively provided with one pressing block, the pressing blocks are fixedly connected with the protective plate carrying seat, and the protective plate carrying seat is fixed on the horizontal bottom plate through the pressing blocks. The automatic testing apparatus can rapidly and accurately test the performance of the battery protective plate, is high in stability, good in consistency, high in production efficiency, low in labor intensity, and low in unqualified rate, enables the production cost to be reduced, and is simple in structure and convenient in use, and is safe and reliable.