Malaysian firms have been reported involve in Asset Back Securities since 1986s where Cagamas is a pioneer. This research aims to examine the factor influencing primary market spread. Least square method and regression analysis are applied for the study period 2004–2012. The result shows one determinants in internal regression model and three determinants in external regression influence or contribute to the primary market spread and are statistically significant in developing the securitization in Malaysia. It can be concluded that transaction size significantly contribute to the determinant primary market spread in internal regression model while liquidity, transaction size and crisis is significant in both regression model. From five hypotheses, three hypotheses support that the determinants have a relationship with primary market spread.


The invention discloses a hand-held box type computer which comprises a handle device and a computer case, wherein the computer case comprises an interface region, a heat dissipation region and a display region. The handle device is movably connected with the computer case. The handle device comprises a handle portion, connecting portions and locking knobs, wherein the connecting portions are arranged at two ends of the handle portion and the locking knobs are used for locking the connecting portions. Each connecting portion comprises a fixed hole. Each locking knob penetrates one fixed hole and is connected with the computer case. Due to the fact that the hand-held box type computer is fully made of a whole metal strip, the hand-held box type computer has the advantages of being large in intensity, firm and reliable due to the fact that the hand-held box type computer is connected with the main body of the computer case through the manual knob, and compact and practical in structure due to the fact that the overlong U-shaped handle portion is capable of evenly bearing the weight of the whole computer case.


With the rapid development of convolutional neural networks (CNN) in the field of deep learning, there has been a great process in brain-computer interaction (BCI) in the past few years due to its efficient processing of images. The review aims to discuss the application of CNN in the BCI design module, especially the data processing module, and analyses the problems and corresponding solutions in the researchers process. The author first briefly describes the application of the CNN architecture in BCI design modules and reviews various research in recent years on regarding improving the accuracy of CNN in BCI data processing modules and maintain high performance, including research on models that tries to solve the problem of commands, changes in feature extraction methods, computational methods, and changing the dimensions of the CNN architecture to attain better computation, etc. By analyzing the problems caused by some researchers using CNN architecture in BCI deep learning applications and related solutions, the author summarizes some of the shortcomings of CNN in BCI research and proposes possible research directions.


We have identified a novel cDNA encoding a protein (named TX) with > 50% overall sequence identity with the interleukin‐1 beta converting enzyme (ICE) and approximately 30% sequence identity with the ICE homologs NEDD‐2/ICH‐1L and CED‐3. A computer homology model of TX was constructed based on the X‐ray coordinates of the ICE crystal recently published. This model suggests that TX is a cysteine protease, with the P1 aspartic acid substrate specificity retained. Transfection experiments demonstrate that TX is a protease which is able to cleave itself and the p30 ICE precursor, but not to generate mature IL‐1 beta from pro‐IL‐1 beta. In addition, this protein induces apoptosis in transfected COS cells. TX therefore delineates a new member of the growing Ice/ced‐3 gene family coding for proteases with cytokine processing activity or involved in programmed cell death.


Abstract In present global reality, companies from the 'developed' countries have out-sourced much of the basic production to countries with lower payroll costs. This has negative consequences for the education of, say, European designers. Their education will eventually loose vital knowledge and close contact with materials and production methodologies. ´ We´are losing our craft. We can, however, empower 'them' by engaging designers with local crafts. This is not unlike the division between craft, workmanship and design but it spans today over cultural and linguistic barriers to a much greater extent than before. Earlier the designer was a practitioner who could perform and advise the production but today only few designers have a background in crafts, and design education has increasingly focused on theoretical skills and downsized workshop competences. A group of furniturestudents started out in Denmark builing models and then traveled to Indonesia to have a conversation with craftsmen through material.


The purpose of this study was to examine the effect of smokeless tobacco (ST) on gingival inflammation as assessed clinically and biochemically by gingival crevicular fluid (GCF) levels of PGE2, IL-1α, and IL-1β. These parameters were compared in ST users (n = 12) and control, non-tobacco using subjects (n = 8) matched for plaque and probing depth levels: Both GI and GCF PGE2 concentration were significantly (P <0.05) elevated at ST placement sites compared to sites in control subjects. A short-term longitudinal trial spanning 7 days also was undertaken within ST users (n = 18) to study the dynamics of gingival inflammation when ST is moved to a new site. At day 0 habitual ST placement sites exhibited a significantly (P <0.05) higher GI compared to nontobacco placement sites. Following transfer of ST to a new placement site, 48 hour GI scores were increased (P <0.05) at this region. Although GCF parameters were not significantly altered, over 80% of the subjects developed dramatic inflammatory reactions i...


This paper focuses on the multi-source remote image management system based on ARCGIS Server, which is based on the exponential growth of remote image volume brought by the rapid development of aerospace industry. Firstly, the framework of multi-source remote image management system is designed, including the application framework and method framework based on B / S architecture. Then, for the analysis of multi-source remote image, the correlation of multi-source remote image, The application-oriented target database is described in detail. Finally, multi-source remote image management system is realized.


A high precision quadrupole mass filter has been developed using the zero-method control circuit. With this method, peak values of a control voltage are compared with a high-precision reference voltage and detected by a diode and signal-producing resistance connected in series. The dc component of the signal is selectively amplified and fed back to a module in the amplifying system of the rf voltage so as to minimize the voltage in excess of the reference voltage. An instrument has been constructed and the doublet of 4He+–D2+ has been successfully separated.


The study is an attempt to examine the rhetorical development realization
of reading texts of the Senior High School (SHS) English textbooks. Based on the
research problem, this study is aimed at finding out the various genres available in
the textbooks for SHS students, describing how those texts achieve their
respective social purposes, explaining how their respective rhetorical
developments serve to achieve their respective social purposes, describing how
the linguistic features serve to accomplish their respective social purposes,
explaining how compatible those texts are with the 2006 English Curriculum
(2006 EC).
The method of the study is discourse analysis, and the approach is
qualitative, however a simple quantification of the evidence in the form of
percentage was done to support the finding. The data are all the reading texts
provided in the six English textbooks published by six different publishers. They
are the six out of fourteen publishers which are recommended by the Indonesian
government to be used to teach English in the SHS. Two of the textbooks are for
the tenth grade; two for the eleventh; and two for the twelfth. They are all a
hundred and fifteen reading texts. The units of analysis consist of two kinds; a text
and a clause. The former is for knowing the genre; it was done by segmenting the
reading text into elements. The latter was done to find out how the elements of the
text are realized based on the three strands of meanings that a clause can encode,
the ones suggested by Halliday (1994). Those three meanings are: the
interpersonal, textual, and the experiential meanings; however in this study the
last meaning, the meaning of the text as representation is the priority since the
texts analyzed were written ones.
The results reveal that there are thirteen genres available in the textbooks
analyzed; two of them, anecdote and commentary, are not required by 2006 EC.
The distribution proportion among the genres is not balanced. Narrations
are very dominant (20 %) and Procedures contribute the least constituent (1.7 %).
Eleven out of a hundred and fifteen reading texts are problematic. This
indicates that most of them have good rhetorical developments and realizations,
therefore they achieve their respective social purposes and can be used as model
texts. Three of the texts are problematic since the kinds of text suggested by the
writer are incorrect. Their rhetorical development analyses prove that they should
have been classified into other genres.
In terms of the rhetorical development realization, ten out of eleven
reading texts are problematic. Therefore they fail to achieve their social purposes.
The following are the reasons : the clauses do not have MOOD for they have no
subjects; some others use inappropriate time circumstances; the clauses do not
make use of the thematization organization for the text to provide cohesion; the
inappropriate use of minor clause is available in the text; and some clauses use
inappropriate modals.
The final conclusion is that most of the reading texts (90.43 %) are
compatible with the 2006 EC
There are four suggestions offered. First, the quantity of narratives in the
textbook should be reduced and given to other genres that have less contribution,
such as procedural texts, recounts, discussions. Second, the users of textbook
should check the reading text that will be used as model texts for the students to
work with, in terms of their rhetorical developments and realizations. Third, the
textbook writer's suggestion on the kind of text should not be taken for granted;
some of them were proved to be incorrect. Fourth, the use of authentic texts
should be done through a careful selection, especially on their quality


High soil pH coupled with low available soil phosphorus (P) and poor utilization efficiency of added P is a significant constraint limiting the productivity of irrigated crops in semi-arid regions. The aim of this three-years field study was to investigate the interactive effect of mycorrhiza (Glomus mosseae) inoculation and phosphorus application on the growth, nutrient uptake and yield components of red pepper (Capsicum annuum L.). The experiment was consisted of four treatments: i) control, ii) mineral-P fertilizer application, iii) mycorrhiza inoculation, and iv) mineral P + mycorrhizal inoculation. The lowest mean fresh fruit yield was measured in 2013, and the highest mean yield was obtained in 2014. Overall, the results indicated that mycorrhizal inoculation and mycorrhiza + phosphorus applications increased yield by up to 25% compared to the control treatment specifically in productive years. The number of spores in soil and pepper yield had a significant positive correlation. Moreover, mycorrhiza inoculation clearly increased plant Zn contents (only significant in 2014). Overall, the study suggest that inoculation of mycorrhiza may increase nutrient (P and Zn) uptake and fruit yield in P supplied pepper planted soils, however, the environmental factors seems to play an important role in controlling their interaction.


Pakistan appeared on the map of the earth on August 14, 1947 as the British left the Indian subcontinent. The World Bank (1992) classifies Pakistan as a low income country on the basis of its per capita GNP. It is the ninth most populous and perhaps one of the fastest growing nations of the world. Unfortunately, Pakistan has also been one of the most illiterate countries of the world. Statistics collected four years after independence show that 86 percent people at that time could not read or write in any language. Taking note of this disturbing situation, almost all the relevant government documents ranging from the reports of various commissions formed to reform education to policy documents like five year plans emphasise eradication of mass illiteracy and provision of universal primary education as an objective of public policy. Free education for all has been traditionally advocated as a policy which would sooner or later achieve these goals. This policy has also been considered desirable from the view point of equity and social justice. At the time of independence, almost all the schools in the rural areas were public schools which charged only nominal tuition. In the urban areas a few private schools usually run by religious or community organisations could also be found. In October 1972, all the private schools were nationalised and education up to tenth grade was made free. Opening of private schools was again allowed in 1979. With this began an era of expensive private schools, particularly in the urban areas, existing side by side with low quality free public schools.


The authors report amplified spontaneous emission (ASE) behaviour from methylammonium lead iodide (CH
 3
NH
 3
PbI
 3
) perovskite films of different thicknesses. The ASE threshold carrier density noticeably decreased with thickness, indicating the existence of different traps with perovskite films of smaller thicknesses. We attribute this behaviour to the presence of surface states, whose origin can result from different practical fabrication steps with samples of small thicknesses. The ASE threshold carrier density increased from 3.29 × 10
 18
 cm
 -3
 at a film thickness of 650 nm to 7.73 × 10
 18
 cm
 -3
 at a film thickness of 80 nm. This work warns that while decreasing the film thickness is of practical importance to reduce the ASE threshold pump current, e.g. in electrically driven light-emitting diodes, the solution processing of perovskites, newly re-discovered for their potential photonic and photovoltaic applications, can be a restraining factor. Band gap renormalisation (BGR) is also observed in the prepared films as a redshift in the ASE peak with increasing the pump power, and the BGR coefficient is estimated to be ~ 6.3 × 10
 -8
 eV cm.


Spectroscopic diagnostics, using intensified high speed CCD camera, was applied to study the arc dynamics in low voltage circuit breakers, in vacuum and in air. Time-resolved emission spectroscopy of the vacuum arc plasma, generated during electrode separation, provided information about the interruption process. The investigations were focused on the partial unsuccessful interruption around current zero. Absorption spectroscopy, in a peculiar setup, was used in order to determine the metallic atoms densities in the interelectrode space of a low voltage circuit breaker, working in ambient air.


Spray droplet size is the main factor affecting the deposition uniformity on a target crop. Studying the influence of multiple factors on the droplet size distribution as well as the evaluation method is of great significance for improving the utilization of pesticides. In this paper, volume median diameter (VMD) and relative span (RS) were selected to evaluate the droplet size distribution under different hollow cone nozzles, flow rates and spatial positions, and the quantitative models of VMD and RS were established based on machine learning methods. The results showed that support vector regression (SVR) had excellent results for VMD (Rc = 0.9974, Rp = 0.9929), while multi-layer perceptron (MLP) had the best effect for RS (Rc = 0.9504, Rp = 0.9537). The correlation coefficient of the prediction set is higher than 0.95, showing the excellent ability of machine learning on predicting the droplet size distribution. In addition, the visualization images of the droplet size distribution were obtained based on the optimal models, which provided intuitive guidance for realizing the uniform distribution of pesticide deposition. In conclusion, this study provides a novel and feasible method for quantitative evaluation of droplet size distribution and offers a theoretical basis for further determining appropriate operation parameters according to the optimal droplet size.


A fundamental aspect of many multiplayer online games is the ability to trade items between players. This might take the form of items that were found in the virtual environment or of purchased assets, but in either case, any multiplayer game that supports trading or exchanging items in the game must do so in a secure manner. We have developed a protocol to solve the problem of secure, peer-to-peer trading in games in which the primary concern is that items are exchanged fairly, and additionally that items are not duplicated. Our protocol enables one-way and two-way trades and can be extended to multi-item trades. We show that our protocol addresses the security threats which it might encounter, and then provide an analysis to demonstrate the scalability of our protocol.


Objective. To explore the effects of silicone gel nanoparticles modified with octacalcium phosphate on the surface (silica/OCP) polymer drugs on the proliferation of osteoblasts and autophagy. Method. Silica/OCP was prepared in vitro, and the quality of the sample preparation was tested through characterization experiments. The osteoblast cell line (hFOB1.19) was treated with silica/OCP, autophagy inhibitor (3-methyladenine (3-MA)), and silica/OCP+3-MA, respectively. The proliferation of hFOB1.19 cells was detected through the methylthiazolyldiphenyl-tetrazolium bromide (MTT) kit. Flow cytometry was used to detect the cell apoptosis. The change in protein beclin1 and P62 expression in hFOB1.19 cells was observed in Western blot. An ROS detection kit was used to detect the content of reactive oxygen species in hFOB1.19 cells. Results. Silica/OCP was a sphere with a particle size of 50 nm to 130 nm and had an OCP phase in electron projection microscopy and X-ray diffraction techniques. The results indicated that OCP successfully modified silica and the material was successfully prepared. An MTT kit and flow cytometry test showed that the cell viability of the cells treated with silica/OCP increased significantly (

 P
 <
 0.05

 ), and the intracellular apoptosis phenomenon was significantly decreased (

 P
 <
 0.05

 ) compared to the control group. Moreover, the inhibition of cell viability and promotion of apoptosis caused by the autophagy inhibitor 3-MA can be rescued. Western blotting demonstrated that the protein level of beclin1 in osteoblasts reached the highest after six hours of treatment with silica/OCP, and the protein level of p62, the substrate protein of autophagy, reached the lowest. At the same time, treatment of cells with the autophagy inhibitor 3-MA and silica/OCP+3-MA found that the protein levels of beclin1 and p62 in the silica/OCP+3-MA group were adjusted back compared to the 3-MA group. After adding the autophagy inhibitor, the reactive oxygen content in the cell was significantly increased (

 P
 <
 0.05

 ) in the silica/OCP group. In the presence of intracellular reactive oxygen inhibitors catalase and silica/OCP, the cell viability of osteoblasts was significantly lower than that of the silica/OCP group but significantly higher than that of the silica/OCP+3-MA group. The apoptosis level of the silica/OCP+catalase group was also significantly lower than that of the silica/OCP+3-MA group (

 P
 <
 0.05

 ) but was significantly higher than that of the silica/OCP group (

 P
 <
 0.05

 ). Conclusion. Silica/OCP nanoparticles can upregulate the level of autophagy in osteoblasts and promote the proliferation of osteoblasts.


This project undertakes research has been done on the Establishment of Educational unit First Basic Education "Mixed School Republic of Argentina" with the theme Development of puppets to stimulate socio-affective development in children of 5-6 years is from this it begins with data collection on the history, origin of the puppets in the world and in our country; also its importance in education; thus being able to implement it as a teaching resource active in educational planning, a study of a means of processing and handling of puppets made, was adapted to the use and environment of each child, allowing participation according to their abilities and creativity; educators were prepared and updated in the proper use of puppets making methodological guide for each topic to be addressed in his teaching puppet enrichment is the key protagonist of a good children's learning. The intention perform is implemented using the puppet as a teaching resource to be present in the classroom, the belief that the puppets are only used for the middle of the show as a mere object of distraction for children with no objective deletion namely, that allows a process of teaching.


The concept of amicitia has long been recognized, but not fully understood, as a determining factor in Rome's rise to supremacy in the Mediterranean world. Burton's monograph, which is based on a PhD thesis written in the 1990s, conclusively shows that this 'ultimate non-institutionalized institution' (357), by virtue of its informal and adaptable nature, perfectly lent itself to the changing requirements of Roman foreign policy during the initial stages of overseas expansion. Following a recent trend in the study of ancient diplomacy, the book is embedded in the broader debates of International Relations theory. In particular, B. uses the tools and concepts of Constructivism to bring out the signicance of language, norms, and ideas, thus providing a valuable antidote to the traditional prevalence of Realism with its focus on power and security. Interestingly, this implies that his perspective sharply diverges from the avowedly Realist position adopted by his PhD supervisor Arthur Eckstein. The main object of the book's attacks is not Eckstein's Realism, however, but the hierarchical clientela model of Roman foreign relations as put forward by Ernst Badian more than a half-century ago. Thus, B. rejects the proposition that status inequality is a distinctive feature of patronage and instead accommodates disparities and uctuations in power within a broadly conceived amicitia paradigm. Drawing on both ancient and modern denitions of friendship, he forcefully argues that a processual model of exchange dynamics is the most appropriate way of understanding the increasingly asymmetrical relationships between Rome and her foreign amici. This interpretive framework is applied in a very substantial body of case studies that focus on the various stages of friendship formation, its subsequent evolution, and eventual dissolution. As regards the rst phase, B. highlights the uncertainties of an initial 'reconnaissance dance' and provides an insightful discussion of deditio, which he views as a ritual regulated by habitus. Given that deditio could be contested if its consequences were manifestly unjust, he contends that the practice was by no means entirely arbitrary but rather opened up discursive space and ultimately encouraged moral restraint. The processual character of friendship emerges very clearly from the ensuing analysis of the longue durée of amicitia and the manifold obligations it involved. Building on this, B. concludes that Rome's friends enjoyed considerable freedom of action within a certain 'arc of political possibility', not only before but also after the city's rise to undisputed hegemony. While this may be true in principle, it should not obscure the fact that his catalogue of typical duties of amici, such as the provision of troops and supplies, is quite different from that of the services performed by Rome herself, which includes items like responding to calls for protection, phrasing demands as requests, and — rather controversially — intervening in internal conicts. Regarding friendship breakdown and dissolution, the issue of trust betrayal is duly highlighted as the foremost concern of the ancient sources, though it is clear that opportunistic motives or, as B. prefers to put it, the 'salience of Roman power' played a crucial rôle as well. On an abstract level, the failure of amicitia is thus reasonably explained in terms of conicting expectations, perceptions, and interpretations by the parties involved. What is striking, however, is the author's reluctance to engage critically with the exercise of Roman power, which he generally considers to be 'hard but fair'. For instance, he argues that, after the Battle of Pydna, Roman harshness towards the Rhodians and Eumenes II of Pergamum was ultimately due to the latter's failure to understand the implications of the growing asymmetry between themselves and the hegemonic superpower (278–99). Overall, Roman violations of des are played down as 'perhaps not exceptional' (300) and tend to be blamed on individuals, culminating in the astonishing claim that there were 'few exceptional cases where the Romans were unable to punish bad faith in their own representatives' (332). Undoubtedly, the chief merit of B.'s book is its consistent concern to approach amicitia relations from the perspective of the sources. Thus, the study convincingly argues for the signicance of moral


—The growing availability of mobile devices, such as smartphones, fitness trackers, and smart watches, induce an increased interest in personal health monitoring. These devices are equipped with the necessary sensor hardware, such as accelerometer and heart rate sensor, for measuring physical activ- ities and heartbeat. However, the accuracy of these measurements is still unclear. In this paper, we evaluate heart rate monitoring with four different device types: a specialized device with a chest strap, a fitness tracker, a smart watch, and a smartphone using plethysmography. The results show similar measurements for the four devices in a state of rest. In contrast, during physical activities the fitness tracker, smart watch, and smartphone may register sudden variations in heart rate with a delay, due to physical movements of the wrist or hand. The specialized device with chest strap shows the most accurate heart rate, highly correlated with measurements obtained with a blood pressure monitor that is approved for medical purposes. These results are important for developers who use data of heart rate for mobile applications and services.


We present a theoretical model allowing to calculate the field back-scattered by a rough surface illuminated by a low divergence Gaussian beam, as well as first experimental results obtained in this configuration using a coherent detection scheme.


Branch-and-bound methods (also called implicit enumeration methods when the branching is done on binary variables) have proved to perform well on many combinatorial optimization problems, provided good bounding functions are known. Quite surprisingly, as emphasized in [3], they have not been studied widely in a multi-objective setting, i.e. when each solution s in the set S of feasible solutions is evaluated by p objective functions f(x) = (f1(x), . . . , fp(x)) to minimize (without loss of generality). Actually, the few existing papers on this topic concern mainly multi-objective integer linear programming [1, 6, 8, 9].


NdBR was applied to the all steel radial truck tire sidewall compound in laboratory and work shop production and compared with widely used NiBR.The results showed that the comprehensive physical properties of NdBR compound were much better than those of NiBR compound,particularly the fatigue and tear properties of compound before and after aging;and the NdBR compound possessed smoother extrudate surface,smaller die swell and higher dimensional stability.The endurance of 10 00R20 test tire with NdBR sidewall was increased by 50% when compared to that with NiBR sidewall.


In this paper, a novel nonlinear oscillator design methodology is proposed to obtain an improved microstrip oscillator performance. It combines the advantages of both quasilinear and nonlinear design approaches. It uses an accurate implemented nonlinear MESFET model, based on multi-bias measurements, and the enhanced harmonic balance nonlinear analysis technique of the HP-MDS. Finally, an 8.5 GHz oscillator is fabricated and an excellent agreement between the theoretical and experimental results is obtained,.


Development of supramolecular adhesives with strong tolerance to extreme conditions has emerged as an important research area. In this study, by balancing supramolecular interactions such as hydrogen bonding interactions, electrostatic interactions, π-π stacking interactions, and cation-π interactions, we designed and prepared a series of two-component supramolecular adhesives derived from small organic molecules. Highly efficient interfacial adhesion with maximum adhesion strength of ~10.0 MPa was realized on various surfaces in air, organic solvents, or liquid nitrogen. Owing to balanced supramolecular interactions, water participation prolonged and increased the tolerance of the adhesives in extreme environments. We demonstrate that the combination of imidazole-based ionic liquids and phenols can be applied for various interfacial adhesions, thereby aiding the development of next-generation adhesives capable of adapting to various extreme conditions in a controlled manner.


combined with practical work the reasons caused the large-area hollow cracking of cement sand plaster on frame column and floor are analyzed;at the same time corresponding treatment measures and quality control methods are proposed as well as some suggestions in order to ensure construction quality.


The purpose of this article is to trace the historic reasons for the conflict between the law of prior appropriation and the protection of flow maintenance and to examine current legislative and administrative methods for the recognition of instream uses. The article also concentrates on a limited number of technical issues which may arise in connection with flow maintenance programs in the appropriation states. The increasing tension between state flow maintenance programs and federally constructed or licensed projects will also be discussed.


Pancreatic cancer (PanC) is one of the deadliest malignancies worldwide and frontline treatment with gemcitabine becomes eventually ineffective due to increasing PanC resistance, suggesting additional approaches are needed to manage PanC. Recently, we have shown the efficacy of bitter melon juice (BMJ) against PanC cells, including those resistant to gemcitabine. As cancer stem cells (CSCs) are actively involved in PanC initiation, progression, relapse and drug‐resistance, here we assessed BMJ ability in targeting pancreatic cancer‐associated cancer stem cells (PanC‐CSCs). We found BMJ efficacy against CD44+/CD24+/EpCAMhigh enriched PanC‐CSCs in spheroid assays; BMJ also increased the sensitivity of gemcitabine‐resistant PanC‐CSCs. Exogenous addition of BMJ to PanC‐CSC generated spheroids (not pre‐exposed to BMJ) also significantly reduced spheroid number and size. Mechanistically, BMJ effects were associated with a decrease in the expression of genes and proteins involved in PanC‐CSC renewal and proliferation. Specifically, immunofluorescence staining showed that BMJ decreases protein expression/nuclear localization of CSC‐associated transcription factors SOX2, OCT4 and NANOG, and CSC marker CD44. Immunohistochemical analysis of MiaPaCa2 xenografts from BMJ treated animals also showed a significant decrease in the levels of CSC‐associated transcription factors. Together, these results show BMJ potential in targeting PanC‐CSC pool and associated regulatory pathways, suggesting the need for further investigation of its efficacy against PanC growth and progression including gemcitabine‐resistant PanC.


DVB-H (Digital Video Broadcasting for Handheld terminals) is a digital transmission standard developed by the international DVB-Project. It was standardized in 2004 and enables small battery powered handheld devices to receive IP data services such as low definition TV services. The DVB-H standard is derived from the DVB-T standard which is used to broadcast TV services in Europe. The convolution code is used as error correction code. In this paper, we have implemented physical layer of DVB-H for 4K mode system. Here we had transmitted a JPEG format of frame of movie through AWGN channel and observed the image quality for different code rates used for convolution coding. The code rates used are 1/2, 2/3, 3/4, 5/6 and 7/8.


A newly developed static apparatus, capable of measuring the vapor pressure in the temperature range 273–368 K and in the pressure range 0.1–1333 Pa, is presented. The apparatus was calibrated by measuring the vapor pressure of recommended reference materials, naphthalene, n-decane, and ferrocene, and thoroughly tested. Subsequently, new vapor pressure data for benzophenone were measured in the temperature range 293–365 K with the aim to establish revised thermophysical data for this compound. Although benzophenone is another material recommended as the reference material for sublimation pressure and enthalpy measurements, the published sublimation thermodynamic data show a significant spread, and the recommendation was made with reservations which involved a reported metastable crystalline phase. We clarify this point based on reviewing the literature reporting the phase behavior and crystallographic studies and an extensive study on the polymorphic behavior of benzophenone performed in the present work....


The robust exponential stability problem for a class of uncertain impulsive stochastic neural networks of neutral-type with Markovian parameters and mixed time-varying delays is investigated. By constructing a proper exponential-type Lyapunov-Krasovskii functional and employing Jensen integral inequality, free-weight matrix method, some novel delay-dependent stability criteria that ensure the robust exponential stability in mean square of the trivial solution of the considered networks are established in the form of linear matrix inequalities (LMIs). The proposed results do not require the derivatives of discrete and distributed time-varying delays to be 0 or smaller than 1. Moreover, the main contribution of the proposed approach compared with related methods lies in the use of three types of impulses. Finally, two numerical examples are worked out to verify the effectiveness and less conservativeness of our theoretical results over existing literature.


Amino sugars are essential for the biosynthesis of the bacterial cell wall and of lipopolysaccharides. The enzyme glucosamine-6-phosphate synthase (GlmS) catalyzes the formation of glucosamine-6-phosohate (GlcN6P) from fructose-6-phosphate and glutamine, which is the first committed step in the biosynthesis of amino sugars. In Escherichia coli, GlmS is encoded together with enzyme GlmU in the bi-cistronic glmUS operon. While the enzymatic activity of GlmU is needed all the time, GlmS is only required, when no external amino sugars are available. Due to the fact that both genes are cotranscribed, it always was a mystery how differential expression of glmU and glmS could be achieved. This work solves this mystery. Following transcription, the glmUS co-transcript is cleaved within the stop-codon of glmU by RNase E, yielding a monocistronic glmS transcript. The amount of the glmS-transcript is regulated by a feedback mechanism in response to an intracellular limitation of GlcN6P. This regulation relies on the two small RNAs GlmY and GlmZ. GlmY and GlmZ are homologous sRNAs, both in sequence and in secondary structure, and act in a cascade to activate glmS expression. When the GlcN6P level decreases, GlmY accumulates and subsequently counteracts processing of GlmZ by RNase E. Only the unprocessed form of GlmZ is able to basepair with the glmS transcript. GlmZ basepairs with the left half-site of a stem-loop structure assisted by Hfq. This prevents access of ribosomes to the Shine-Dalgarno sequence. This interaction destroys the inhibitory stem-loop, thereby allowing efficient translation of glmS. In addition, the data indicate that the protein YhbJ might might play a role in this process. In a ΔyhbJ mutant, processing of GlmZ is abrogated and glmS expression is strongly induced. Therefore, it appears feasible that YhbJ is an intermediary factor in the GlmY/GlmZ cascade, which acts between GlmY and GlmZ and regulates GlmZ p rocessing in a GlmY-dependent manner. Both expression and abundance of GlmY, which acts at the top of this regulatory cascade, is extensively regulated. GlmY is continuously targeted for polynucleotide phosphorylase dependent degradation by poly(A)polymarase dependent polyadenylation. This removes active GlmY species from the cell and keeps the cascade sensitive to the GlcN6P signal. Gene glmY is expressed from two overlapping σ70- and σ54-dependent promoters. Both promoters initiate transcription at the same nucleotide. Therefore, identical GlmY species are generated from both promoters. The σ70-dependent promoter is active mainly during the exponential growth phase, while activity of the σ54-dependent promoter increased during transition to stationary phase. The σ70-dependent promoter appears to be constitutively active. In contrast, the σ54-dependent promoter subject to regulation by the GlrR/GlrK two component system and YhbJ. GlrR is a σ54-dependent activator protein and is shown to bind to three specific binding sites of the consensus sequence TGTCN10GACA, which are present upstream of the glmY promoter region. The activity of the σ54-dependent promoter depends on the presence of GlrR. The activity of this promoter is also reduced in a ΔyhbJ mutant. This effect is independent from GlmY and GlmZ, but the mechanism of YhbJ-dependent modulation of glmY σ54-promoter activity is unknown. Activity of the glmY-promoters is not altered in response to GlcN6P limitation. Therefore, the GlcN6P signal must be sensed post transcription of glmY. In summary, this work shows how differential expression of the bi-cistronic glmUS operon is achieved by post-transcriptional regulation of glmS expression by two homologous sRNAs, GlmY and GlmZ. These sRNAs act in a cascade and are the first example for hierarchicall y acting sRNAs. In addition, this work presents the first example of overlapping σ70- and σ54-dependent promoters that initiate transcription at the same nucleotide.


The project here presented aims to discuss the context of emergency and development of the Production Engineering in academic environments in Brazil and South Korea. The comparison makes sense taking into account that both countries started their Science and Technology policies from similar points, back in the 1960s and 1970s decades. However, the way these trajectories differ can be understood by the way each country invested in Applied Science training, such as Industrial Engineering. Starting by the comparison of undergraduate programs from both countries, using multivariate statistics, it is possible to discuss how the Industrial Engineering is thought and developed, the main issues related to curriculum innovation and how each environment differ in terms of engineering profession.


The objective of this study was to evaluate the effect of natural and synthetic complexing agents on Cd²⁺ adsorption characteristics of metal hydroxides and silicate clay minerals. The solution pH at which 50% of the initial solution Cd²⁺ was adsorbed was 5.40, 7.00, 7.80, and 8.30 for Al(OH)₃, Fe(OH)₃, montmorillonite, and kaolinite, respectively. The presence of citrate (C₆H₅O₇³⁻) depressed Cd adsorption on Al(OH)₃, by approximately 25% in acidic solutions. The addition of EDTA (C₁₀H₁₆O₈N₂) depressed the Cd adsorption on both Al and Fe hydroxides, montmorillonite, and kaolinite in acidic and alkaline solutions. The water-soluble organic fraction from sewage sludge enhanced Cd adsorption by both kaolinite and montmorillonite in alkaline solutions. The water-soluble organic fraction from an organic soil (Terra Ceia muck) increased Cd adsorption by Fe(OH)₃ only under acidic conditions. Preliminary results indicated that considerations of Cd retention by soil constituents should include not only the aqueous chemistry of Cd and the surface chemistry of the adsorbent, but also the chemistry of natural and synthetic complexing agents. The interaction of Cd and various complexing agents can play an important part in determining the fate of this metal in the soil-water-plant environment.


Moving to more electric aircraft, a redundant configuration provide us an opportunity to introduce electro hydrostatic actuators into primary flight control system. Redundant mechanism produce a problem called force fighting (force difference b/w two actuators) that can damage aircraft control surface. This paper presents a model reference adaptive controller. Parameters of controller have been found with help of Lyapunov's stability theorem. Stability of controller is checked by using lyapunov's theory. Reference model is designed on the dynamics characteristics (rise time, settling time etc.) of hydraulic actuator. To assist the adaptive controller to improve synchronization and load rejection performance, a PID controller is used that takes force fighting as an input signal. This input signal is a measure of coupling effect. It is observed that adaptive controller not only completely removes initial force fighting but also it improves load rejection performance significantly. The whole design and experimental results have been done in MATLAB/Simulink.


Automatic meter reading (AMR) technologies play an important role for smart grid. The architectures of physical layer and baseband circuits are proposed for a wireless AMR enterprise standard the most significant features of which are its coverage distance and power consumption potentially. All-digital baseband circuits for the wireless AMR application are designed and implemented in this paper. A novel Gaussian frequency-shift keying (GFSK) demodulator converting frequency offset in received signals to a DC component which is easy to be cancelled is also presented. The circuits are synthesized in UMC 1.8 V 0.18 μm process, and the results show that the chip consumes 82.97 μW of power and occupies 2.303 mm2 of silicon area. This baseband circuits meet the wireless AMR enterprise standard specifications, and would be integrated in a wireless AMR SoC in the future.


General comments: we agree with the reviewer, and in the revised version of the manuscript will restructure the discussion section in order to provide further insights on model performance. The model domain, which includes a majority of un-forested areas and displays a strong seasonality in precipitation, provides unique opportunities for assessing sources of error in isolation, including conceptual model and input data errors.


BACKGROUND
Heightened distress at the time of a loved one's lung cancer diagnosis may motivate relatives to quit smoking or could undermine cessation.

METHODS
Relatives of new lung cancer patients at Duke were surveyed by telephone to assess diagnosis-related depression, distress, and motivation for smoking cessation.

RESULTS
Relatives who reported above average avoidant and intrusive thinking patterns, depressive symptoms or worry were more likely to report that the patient's diagnosis increased their intentions to quit than the less distressed.

CONCLUSIONS
Interventions are needed that encourage smoking cessation as a strategy for adaptively coping with a loved ones' lung cancer diagnosis.


On November 14, 2016 an earthquake struck the rural districts of Kaikōura and Hurunui on New Zealand's South Island. The region—characterized by small dispersed communities, a local economy based on tourism and agriculture, and limited transportation connections—was
 severely impacted. Following the quake, road and rail networks essential to maintaining steady flows of goods, visitors, and services were extensively damaged, leaving agrifood producers with significant logistical challenges, resulting in reduced productivity and problematic market access.
 Regional tourism destinations also suffered with changes to the number, characteristics, and travel patterns of visitors. As the region recovers, there is renewed interest in the development and promotion of agrifood tourism and trails as a pathway for enhancing rural resilience, and a growing
 awareness of the importance of local networks. Drawing on empirical evidence and insights from a range of affected stakeholders, including food producers, tourism operators, and local government, we explore the significance of emerging agrifood tourism initiatives for fostering diversity,
 enhancing connectivity, and building resilience in the context of rural recovery. We highlight the motivation to diversify distribution channels for agrifood producers, and strengthen the region's tourism place identity. Enhancing product offerings and establishing better links between different
 destinations within the region are seen as essential. While such trends are common in rural regions globally, we suggest that stakeholders' shared experience with the earthquake and its aftermath has opened up new opportunities for regeneration and reimagination, and has influenced current
 agrifood tourism trajectories. In particular, additional funding for tourism recovery marketing and product development after the earthquake, and an emphasis on greater connectivity between the residents and communities through strengthening rural networks and building social capital within
 and between regions, is enabling more resilient and sustainable futures.


Introduction: Slice Encoding for Metal Artifact Correction (SEMAC) [1] fully corrects metal-induced artifacts in MR images by employing additional z-phase encoding to resolve distorted excitation profiles. The spins displaced due to metal-induced susceptibility are repositioned to their actual locations, and the signals from all excited slices are combined to reconstruct the 3D volume. There are two main problems of SEMAC technique (or another similar MAVRIC technique [2]), namely long scan times associated with the additional z-phase encoding and low signal-tonoise ratio (SNR) due to the inclusion of noise in the combination of SEMAC-encoded slices [1]. Acceleration techniques such as parallel imaging reduce the scan times of SEMAC at the cost of further loss in SNR [3]. In this work, we address the two problems of SEMAC with an alternate sampling and reconstruction procedure to exploit the correlation and sparsity in SEMAC-encoded slices.


cases. IapillomntouwbZsl-uption.: ? Cond(6gylom ae (Dr. I AG E).-A sinigle wvomnan, aged 33, lady's maid, about eighteen months ago, liad a " boil" near tlse left armpit. Now, this l)ait, and the left breast, and part of the flanik, are covered wvitlh reid aised warty growvths ; the extending edges are nearly an inich above the skin. There are similar growtths about the vulva and thighs, strongly suggestive of coid(lylomata. The lips are similarly affected. The tongue is fissured. The patient's fatlher died of cancer ; her mother of plitlhisis. There is nio hiistory consonant with syphilitic in-fectioni. Onie surgeoni considers the rashl due to iodide of potassium. The case seems to be unique; but there is a curiously analogotis one, in some respects, in a patient of Dr. Pye-Smith's, now lying in aln opposite bed, and evideently syphilitic. Pnzeumiionia of Apex v. P/it/iisis (Dr. FAGGE).-Dr. Fagge lhas often been rightly guided in diagnosis on this point, by nioting the suddenness of inivasion in the pneumonic cases. A lad, lying semi-delirious, with dulniess at the left apex, tubular breathinig, anid crepitus, was taken ill with rigor, etc., on Wednesday last, havinig been well before. Tlle probabilities are of pneumonic consolidationi.


Fuzzy-Mean(FCM) clustering algorithm is one of the widely applied algorithms in the fuzzy clustering,in which two important parameters: fuzzy weighting exponent and the number of clustering must be given appropriate assignment before the clustering analysis.Otherwise,the result of clustering by FCM will be affected.We will discuss the method of determining the two parameters in this paper.


When developing new deep-water fields in locations such as the Gulf of Mexico (GoM), understanding the aquifer's size and its connectivity are two important variables that dictate the presence or absence of any future water injection project. Because of the substantial scale of thelarge size of investment associated with developing fields in deep offshore environments, it is important to identify the key factorsdrivers drivingthat would help with decisions onaround optimizing the development optimization, and thus, preventing the operators from incurring unnecessary expenses. The first such factordriver is the assessment of the aquifer's potential size and connectivity of the aquifer. The second factordriver is the understanding of the aquifer's strength. TWe do not feel that this second parameter has not been sufficientadequately assessquantified in the literature, so we propose a new aAquifer iInflux iIndex (AII) in order to address this gapfor that purpose.
 Prior to any petroleum field startup of any petroleum field, it is important to plan for waterflooding, especially if there is uncertainty around the aquifer's strength is uncertain. We use data from several GoM fields in GoM as examples, as well as their corresponding AII, so as to provide guidance on designing an effective conceptual water injection project prior to startup.


Massive MIMO involves the use of large scale antenna arrays for high-gain adaptive beamforming and high-order spatial multiplexing. An important design challenge in Massive MIMO systems is the acquisition of channel state information at the transmit array, where accurate channel knowledge is critical for obtaining the best performance with Multi-User MIMO transmission on the downlink. In this paper, we explore the use of a product codebook feedback methodology for two-dimensional antenna arrays where the codebook feedback strategy is decomposed into two separate feedback processes, one for azimuth and one for elevation. We specifically address the case where the transmit array consists of cross-polarized antennas and show how two separate codebook feedback processes can reduce reference signal overhead and simplify the mobile complexity while providing significant gains in performance over existing LTE configurations.


Twenty-five student nurses staged an all-night 'sleep out' in the grounds of York District Hospital last week in protest at the proposed tripling of their rents.


Teaching reform of moral education in vocational colleges should go toward the direction of practice and subjectivity.Practice emphasizes the sustainable development of the formation of students ' moral and continuous improvement of the moral life,stresses the importance of students ' needs and interests for moral cultivation,emphasizes the close connection between students ' moral education life and social life.The teaching of subjectivity moral education should combine teacher's subjectivity and student's subjectivity to abandon the disadvantages of killing students' subjectivity in traditional moral education teaching.Practice and subjectivity are complementary and mutually reinforcing in the teaching of moral education.Only setting up the flag of practice and subjectivity can the teaching reform of moral education find a valid new road.


The materials for this paper were obtained from three sources: (a) the examination, on successive occasions during the period December 1939–April 1940, of volunteer subjects, mainly from common lodging houses in east London, prior to their treatment with pediculicides, (b) the examination, during April 1940, of large numbers of men from common lodging houses, Salvation Army hostels, night refuges and other sources, in a search for further suitable subjects for control experiments, and (c) the study of the process of infestation of shirts issued to selected volunteers and worn continuously over a period of 10 days. The material from the first source is largely selective, since infested volunteers were specifically invited; that from the second source is more representative of the population of cheap hostels, since no emphasis was laid on the presence of lice, the men being induced to submit to examination by the offer of payment. It is, however, obviously not a random sample since it represents volunteers, and neither it nor the source (a) material should be used as a measure of the frequency or degree of infestation normal to the corresponding group of the city population.


In this paper a mathematical model for prediction of phosphorus removal with total phosphorus (TP) as the check index in horizontal subsurface flow constructed wetlands was developed. The model considered the water flow and transportation, diffusion, dispersion and biochemical reaction of phosphorus. The physical and biochemical parameters of the model were calibrated by one set of the experimental data. Then the model was valided by another set of the experimental data. The predicted effluent TP concentrations were well agreed with the actual effluent TP concentrations. The model can be used to simulate the phosphorus removal effect in horizontal subsurface flow constructed wetlands. The average removal rate of TP for domestic sewage in planted and unplanted constructed wetland with high concentration of influent were 88.22% and 85.06% respectively, while their removal rates were 94.23% and 90.77% respectively with low concentration of influent. So vegetation had improvement effect on TP removal.


Safety device to prevent damage of a device for transmitting torque from a manual or motorized drive means of a drive shaft to a pivoted member which is rotated by a certain angular measure in at least one direction of rotation, which security device comprises two rotatable relative to one another, nested elements ( 1, 10), wherein the one element (1) are fixed to the rotatably mounted component and the second element (10) on the drive shaft and a member (1 or 10) to the other (10 or 1) via at least one with exceeding of a specific torque that can be disengaged coupling element (15) is coupled, and the drive by disengaging the second element (10) at least over the remaining angular continues to rotate relatively with respect to the first (1) and the at least one coupling element (15) is a radially acting spring-loaded latching element with the direction of rotation of element e (1, 10) bent round or hemispherical shape or a wedge shape (26) and at the one element (10 or ...


The Chinese economy is at a crucial turning point of high-quality development and transformation. The advancement of the economic structure and the promotion of green economic development will be accelerated with the establishment of a new development model with green technological innovation at its core. Innovation in green technology has always been strongly influenced by financial development. There are now several advantages that digital financial services offers over traditional finance, opening up new avenues for the advancement of green technology. As a critical factor affecting the technological development in green innovation, investment and funding status of businesses is essential, directly affecting the operation of the financial system in the whole area of green innovation and determining the speed and quality of the advancement of Chinas green technology. In order to discuss digital finances specific role in alleviating financial constraints and promoting green investment, this article principally examines, from the viewpoints of investment and financing, the impacts of China's digital finance growth ongreen technologies.


We consider here some peculiarities in ranging with a space- based lidar 'Balkan-1' of the ocean surface for two modes of the space station 'Mir' orientation used during lidar measurement sessions. To demonstrate the peculiarities we have analyzed regular and random fluctuations of the lidar optical axis position in space that occurred in the measured sessions conducted. Analysis made allows us to discuss possible causes of the systematic difference between the ballistic calculated data on range and the values of slant range measured with the lidar in both modes of the station orientation.


The preparation of a pyrrolo[9,10]phenanthrene nucleus is described. The utility of the template as a potential DNA intercalating drug delivery system is demonstrated by synthesis of a derived bis chloroethylamine alkylating system


72 This is the magnetic resonance image (MRI) of the brain of a 23-year-old female with a 20-month history of headache, progressive blurring of vision, somnolence, constipation, cold intolerance and amenorrhea. Physical examination showed bitemporal hemianopsia and decreased muscle stretch reflexes for all extremities. She had normal serum sodium and urine specific gravity, modest elevation of prolactin level, low thyroxine level with inappropriately normal thyrotropin (secondary hypothyroidism), and markedly decreased 8 AM serum cortisol. The MRI of the head with gadolinium showed a moderate-sized peripherally enhancing sellar and suprasellar cystic mass measuring 3.3 x 3.6 x 4.0 centimeters which is partly hemorrhagic or containing proteinaceous material, that causes marked compression of the overlying optic apparatus. Imaging findings are most compatible with a craniopharyngioma. Normal 0 false false false EN-US X-NONE AR-SA /* Style Definitions */
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 Figure 1. Sellar mass exhibiting pre-existing internal T1 hyperintensity and evidence of sedimentation leveling. Figure 2. The sellar mass is asymmetric towards the left, extending to the left cavernous sinus region. It causes mild to moderate expansion of the floor of the sella. This is the magnetic resonance image (MRI) of the brain of a 23-year-old female with a 20-month history of headache, progressive blurring of vision, somnolence, constipation, cold intolerance and amenorrhea. Physical examination showed bitemporal hemianopsia and decreased muscle stretch reflexes for all extremities. She had normal serum sodium and urine specific gravity, modest elevation of prolactin level, low thyroxine level with inappropriately normal thyrotropin (secondary hypothyroidism), and markedly decreased 8 AM serum cortisol. The MRI of the head with gadolinium showed a moderate-sized peripherally enhancing sellar and suprasellar cystic mass measuring 3.3 x 3.6 x 4.0 centimeters which is partly hemorrhagic or containing proteinaceous material, that causes marked compression of the overlying optic apparatus. Imaging findings are most compatible with a craniopharyngioma. 72 Normal 0 false false false false EN-US X-NONE AR-SA /* Style Definitions */
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The ability to accurately characterize the thermal efficiency of turbine stages with cooled components is essential to advance turbine technologies. There are many methods for calculating aerodynamic efficiency of turbomachinery components, with most encompassing either single point or simple integrated values at the inlet and exit locations. For cooled turbine stages, there is an added complexity of how to incorporate cooling flow streams. Although these techniques may include multiple cooling flows, a fully-mixed assumption is often invoked without directly accounting for distributions of cooling flow in the annulus. However, the distribution of cooling flows in turbine stages may vary significantly depending on the location and nature of injection. This study addresses how calculated efficiency may vary depending upon how cooling flows are injected and the manner in which these cooling flows are accounted. The analyses utilize experimentally measured cooling flow concentration profiles to motivate a new approach for calculating cooled turbine efficiency with weighted cooling flow distributions. Validation data for a one-stage high-pressure turbine geometry from the Energy Efficient Engine (E3) program are assessed to determine the range of influence for cooling flow distributions. Results show that cooling flows injected at similar axial positions can have unequal influences on integrated stage efficiency based on known distributions of cooling flow and other properties at the turbine stage exit plane. In some cases, deviations approaching half a point of efficiency can be observed relative to traditional equations, and the magnitude of influence is shown to increase as stage total pressure ratio decreases.


Objective To understand the main factors influencing activity of total superoxide dismutase(T-SOD)in erythrocyte membrane in workers occupationally exposed to quartz dust.Method Totally,179 workers occupationally exposed to quartz dust were studied by cluster sampling at a ceramics factory in Foshan city,Guangdong Province and two milliliters of venous blood were drawn from each of them with heparin as anticoagulant.Activity of T-SOD in erythrocyte membrane was measured with xanthine oxidase method introduced in a reagent kit,membrane protein was determined with Coomassie brilliant blue method and mean activity of T-SOD was calculated.Workers were interviewed with questionnaire foreight possibly related factors.Air concentration of quartz dust and level of noise at varied sites of the workplace were measured.All the data collected were fitted to a non-conditional logistic regression model with dichotomous activity of T-SOD(equal to or greater than and less than reference level)as dependent variable and other related factors as independent variables,to find main factors influencing it.Result Length of exposure to dust,air concentration of quartz dust at workplace,use of protective masks,tea drinking and cigarette smoking were eventually entered the regression equation at significance level of 0.05.Conclusion The main factors influencing the activity of T-SOD in erythrocyte membrane in workers occupationally exposed to quartz dust included length of exposure to dust,air concentration of quartz dust at workplace,wearing protective masks,tea drinking and cigarette smoking.


This chapter reviews litigation issues particular to human rights lawsuits from the initial development of a case through the filing and service of the complaint. It focuses on the common factors involved in preparing a case under any of the statutes, although the emphasis is on the Alien Tort Statute (ATS) and Torture Victim Protection Act (TVPA). Human rights claims are likely to be originated by human rights victims or their family members, or through investigations triggered by human rights activists or lawyers. The Federal Rules of Civil Procedure incorporate a flexible approach to complaint drafting, requiring only that a complaint give fair notice of the claims asserted against the defendant. As human rights cases wind their way slowly through the federal courts, individual defendants have ample time to move their assets out of the United States, to protect themselves against an eventual judgment. Keywords: Alien Tort Statute (ATS); federal courts; human rights victims; Torture Victim Protection Act (TVPA)


COVID-19 is co-existing in the contemporary World. During the 2.2-year period (2020-1-1 to 2021-3-3) when the COVID-19 comes into play, the World has recorded around 440,553,000 cases, averaging 557,662/day. Death toll so far is around 5,993,000, with a mortality rate of 1.36% (compared to 1.95% till end-Nov 2021 when the Omicron Variant came into play). Dr. Angelique Coetee (Head of S. Africa Medical Association) has voiced recently that the symptom of the new variant Omicron is mild and there is no need for patients to be hospitalized. Yet, due to its fast propagation speed resulted from the 32 mutations on the Spike Protein and the 10 mutations on the 'receptor binding domain' which gain entry to the human cells, it has attracted global attention, and many countries have closed their borders to relevant regions.

 This research paper is based on the impact of the consistent Sunspot cycle's 11-year variation on mankind. Riding on a similar paper published at the Oxford Business & Economic Conference in 2007 on a hypothesis of Sunspot on "Uni-Economic" which has been award the best paper at the time, the current paper is focusing on the impact of Sunspot, but on the front of human health as affected by the COVID-19 Pandemic. Dataset over 4 centuries and converging on the past 60 years have been collected to verify the hypothesis of Sunspot on Pandemic with confidence level above 95%.

 2019 experienced the lowest sunspot in the history of mankind at 281 days without any Sunspot. In other words, there is a subtle lack of "Energy" for mankind. It is well recognized that, in Tradition Chinese Medicine (TCM) theory, Energy (Chi) is the most important drive and defense line for our human body.

 Through literature review and critical analysis, most of the Pandemic in the human history occurs at the Sunspot Minima years when there were serious lacking of Chi for mankind. Nevertheless, it is expected that the Sunspot day-count will be almost daily in 2022, and hence its radiation on Earth will be approaching Maxima. Therefore, the COVID-19 will subside naturally, and the virus (including the weak Omicron, resulting in the Mortality rate dropping from 1.95% to 1.36% since encountered in Dec 2021) will become an Endemic. This has been proven by history.


We report a lattice dynamics study of relative stability of various phases of natural silicates MSiO4 (M=Zr, Hf, Th, U) as a function of pressure (P) and temperature (T), which is important in the context of their use in nuclear waste storage media. Extending our previous work on ZrSiO4, the Gibbs free energy has been calculated using a transferable interatomic potential in various phases over a range of P and T. Due to an interesting interplay between the vibrational entropy and atomic packing, the zircon (body centered tetragonal, I41/amd), scheelite (body centered tetragonal, I41/a) and huttonite (monoclinic, P21/n) phases occur at different P and T. It is shown that for ThSiO4 at high P, the huttonite and scheelite phases are favored at high and low T respectively. However, for both USiO4 and HfSiO4 the huttonite phase is dynamically unstable and the scheelite phase is stable as the high pressure phase. In fact, the calculations reveal that the stability of the huttonite phase is determined by the ionic size of the M-atom; this phase is unstable for the silicate with the smaller Hf and U ions and stable with the larger Th ion. The calculated phase diagrams are in fair agreement with the reported experimental observations. The calculated structures, phonon spectra, and various thermodynamic properties also fairly well reproduce the available experimental data. The low-energy phonons in the huttonite phase that contribute to its large vibrational entropy are found to involve librational motion of the silicate tetrahedral units.


The skull conductivity strongly influences the accuracy of EEG source localization methods. As the conductivity of the skull has strong inter-individual variability, conductivity estimation techniques are required. Typically, conductivity estimation is performed on data from a single event-related stimulation paradigm, which can be explained by one dipole source. A conductivity value for the skull can be estimated as the value for which the single dipole source provides the best goodness of fit to the data. This conductivity value is then used to analyse the actual data of interest. It is known that the optimal local skull conductivity when modelling the skull as one compartment depends on the amount of spongiosa present locally. The research question arising is: Is conductivity estimation based on data from a single paradigm meaningful without accounting for the internal skull structure?


Transfer theories, which are closely related to evaluation theory, have been developed from a holistic perspective, but most of empirical transfer research has not effectively utilized holistic models to investigate transfer of learning until the late 1990s. Additionally, little has been done in examining the relationship between situational variables, demographic variables, and transfer system characteristics. This study contributes to transfer research by examining the combined effects of situational and demographic variables on a holistic model of perceived organizational transfer systems. A key finding was that demographic variables make only a marginal contribution to predicting transfer system characteristics when compared to situational variables. It seems clear that the differences in transfer system characteristics depend on diverse situational influences, primarily due to types of training programs and types of organizational cultures. This finding does not support one-size-fits-all transfer interventions. Future research may focus on investigating benchmark transfer practices in certain types of organizations or industries to empirically identify the true leverage points of a diagnosing instrument of transfer—the Learning Transfer System Inventory—for interventions and change.


The article presents a generalized method for calculating the actual performance of low-speed longstroke air compressor stages of compression, based on determining the flow rate as a set of coefficients reflecting the influence of various factors on productivity losses. The method takes into account the design and operating features of low-speed long-stroke air compressor stages of compression and differs significantly from a similar method used to calculate high-speed stages of reciprocating compressors


PURPOSE:To provide a parallel operation control device which allows an allotted current to be balanced at a high speed in a power-supply system where a plurality of instantaneous control type AC output converters are connected in parallel and are operated in parallel for a common load. CONSTITUTION:Current DELTAI1 which flows between converters is detected by a current-detection circuit 406, ZXDELTAI1 is obtained by a virtual impedance circuit 405 for limiting cross current, and a signal V*(=VP*-ZXDELTAI1) which is obtained by subtracting this signal from a bus voltage command value V* by a subtractor 504 is used as a command value of an instantaneous voltage control circuit 403. On the other hand, a common oscillator 8 prevents a voltage phase difference of each converter from being generated, thus eliminating an effective content of the cross current.


This paper introduces several methods of massive data's importing to and exporting from MATLAB rapidly and accurately,and gives some cases.The methods resolve the many problems appearing in inputting directly origin data into'Command Window'of MATLAB in past,so they have important significance in assuring the accuracy of analysis results and in accelerating MATLAB'S application in statistical analysis.


THIS NOTE has as its major objective to establish that the main theme of Leach's paper "The Structural Implications of Matrilateral Cross Cousin Marriage"'2 is based on invalid arguments. My purpose is to dispel certain analytical confusions which impede lucid discussion fasymmetric cross cousin marriage systems, e pecially those of Australia and Melanesia. I present here a further development of ideas introduced lsewhere, primarily in two papers, "Structural Contrasts Between Symmetric and Asymmetric Marriage Systems: a Fallacy"3 and "Implicit Double Descent in Southeastern Australia nd the Northeastern New Hebrides,"' the latter written i collaboration with R. B. Lane. Since the first of these two papers has been criticized by Leach," the major portion of this note will deal with is criticisms. In his discussion fmy paper, Leach accuses me of indulging in fallacious reasoning and terminological ambiguity, of formulating i ept propositions, and of improper or implausible ethnographic reporting. His procedure is to misrepresent and distort both the substance and the argument of my paper; to insert inappropriate and unwarranted inferences of his own without indicating their origin, in order to later demolish these; and to gratuitously impute to me patently preposterous views. Leach's main contentions regarding my paper are (1) that I confuse 'prescriptive' with 'preferential,' (2) that I confuse reality with models, (3) that my point is not original, (4) that I ignore jural authority, (5) that here is no fallacy, and (6) that since prescriptive patrilateral cross cousin marriage does not exist, the second half of my paper need not be considered. He treats only my discussion f matrilateral cross cousin marriage. The first hree contentions are untrue and I shall illustrate his below. The fourth point concerns a fundamental flaw in Leach's method of analysis and I shall relate this also to his general theory of matrilateral cross cousin marriage. The fifth and sixth points are discussed last. Leach commences his critique by noting the analytical distinction between prescriptive and preferential marriage systems. I employ the concept "prescriptive"


This report describes experiments which compare conditions necessary to isolate mitochondria uncontaminated with nuclear chromatin using a KDL grinding mill.


Mammary hipertrophy in women can not only be an aesthetic, but also a functional defect, since it is a frequent cause of neck pain and it is also related to ...


Tsunami deposit is a direct evidence of inundation area of past tsunamis. A large number of publications have been written about the diagnostic signatures and identification criteria for past tsunamis, including sedimentological, micropalaeontological evidences. However their identification is still difficult because all criteria is neither necessary condition nor sufficient condition due to various origin, mechanism and temporal variation of tsunami deposits. Geochemical discrimination is now recognized as other useful proxy which dose not depend on the researcher's subjectivity, especially in the case that other proxies can not be used. Especially, geochemical indicator is suggested to be useful in identification beyond the limit of recognizable sand deposition. In this study, we established the criteria for geochemical discrimination of 2011 Tohoku-oki tsunami deposits and their background marine sediments using machine learning techniques. For 18 analyzed elements, several tens of elemental combinations show the discrimination rates higher than 99%. By applying the criteria to past tsunami deposits in the Sendai Plain, we discuss the validity and effectiveness of the method.


The results of modeling the processes of annealing cold-worked coils of extra-thin steel strip of high quality
in protective atmospheres of hydrogen and nitrogen in bell-type furnaces are presented. An algorithm for calculating
the optimal value of the heating time is given, taking into account the thermophysical properties of both processed
hard-worked coils of extra-thin steel strip and protective atmosphere gases. A technique for optimizing the modes
of annealing of hard-worked coils of extra-thin steel strip in a bell-type furnace in a pure nitrogen environment relative
to the basic mode in a pure hydrogen environment is presented.


OBJECTIVE:To compare neoadjuvant chemoradiotherapy and surgery(CRT+S) with surgery alone(S) for resectable esophageal squamous cell carcinoma.METHODS:PubMed databases was used to search randomized controlled trials(RCTs) comparing the CRT+S and S treatment for resectable esophageal squamous cell carcinoma.The RevMan 5.2 software was used for meta-analysis.RESULTS:This meta-analysis included 10 RCTs.There was no statistical significance in the 1-year survival rate between the CRT+S group and S group(RR=1.03,95%CI=0.96-1.10,P=0.37).The 3-and 5-year survival rates were significantly higher in the CRT+S group(RR=1.32,95%CI=1.17-1.50,P0.001;RR=1.24,95%CI=1.03-1.49,P=0.02).Compared to the S group,CRT+S group had lower surgery rate,higher postoperative complication incidence rate and mortality rate(RR=0.84,95%CI=0.72-0.99,P=0.04;RR=1.25,95%CI=1.02-1.53,P=0.03;RR=2.34,95%CI=1.37-3.99,P=0.002),while the R0 resection rate was significantly higher in CRT+S group(RR=1.18,95%CI=1.06-1.32,P=0.002).The postoperative local recurrence and distant metastasis rates were similar in two groups(RR=0.82,95%CI=0.31-2.16,P=0.68;RR=0.86,95%CI=0.60-1.22,P=0.39).CONCLUSION:CRT+S can significantly improve the long-time survival rate and R0 resection incidence of people with resectable esophageal carcinoma.


In critically ill patients it is imperative to resolve and treat the cause of haemodynamic shock as quickly as possible in order to save lives and minimize end-organ damage. Intensive Care doctors trained to perform echocardiography can rapidly diagnose and effect management changes in hypotensive patients. A goal-directed approach is required seeking to urgently identify and differentiate distinct clinical syndromes that may occur in this setting. Such an approach utilizes the primary transthoracic echocardiographic subcostal, parasternal, and apical windows and identifies the key issues that can be addressed in the available views. Key to the success of goal-directed echocardiography is the integration of clinical and echocardiographic data in each individual patient. Keeping an open mind regarding the coexistence of more than one cause of hypotension and the need for more comprehensive echocardiography testing is important. Specific situations such as papillary muscle rupture, localized tamponade following cardiac surgery and prosthetic valve malfunction are more reliably diagnosed using the transoesophageal approach. Some diagnoses, such as aortic dissection, acute mitral or aortic regurgitation and acute cardiomyopathy require a multidisciplinary approach and immediate consultation with Cardiology and cardiothoracic services will be required. The simultaneous interpretation of echocardiographic images and the institution of active management are what distinguish critical care echocardiography.


OBJECTIVE
To compare paroxetine with placebo and other antidepressants across multiple efficacy and tolerability outcomes.

DATA SOURCES
Searches were conducted in MEDLINE (1966-2004), EMBASE (1980-2004), CINAHL (1982-2004), all Evidence-Based Medicine Reviews (1991-2004), HealthSTAR (1975-2004), BIOSIS (1980-2004), and PsycINFO (1840-2004). Medical Subject Headings (MeSH) included "paroxetine" OR "Paxil" exploded. The searches were not restricted by language, publication type, or study design.

STUDY SELECTION
A study report was included if it described a randomized trial of paroxetine versus placebo or other antidepressants for patients with depressive disorders. Records were screened independently by 2 reviewers under the supervision of another reviewer.

DATA EXTRACTION
Three investigators abstracted data, including study design, trial characteristics, and psychiatric assessment tools, using a prespecified form. Two investigators assessed quality of reporting using Jadad's scale.

DATA SYNTHESIS
We included 62 unique randomized controlled trials. Paroxetine yielded consistently and significantly better remission (rate difference [RD]: 10% [95% CI = 6 to 14]), clinical response (RD: 17% [95% CI = 7 to 27]), and symptom reduction (effect size: 0.2 [95% CI = 0.1 to 0.3]) than placebo. Such consistency in the evidence base was not observed between paroxetine and other antidepressants. Pairwise comparisons of paroxetine and venlafaxine, mirtazapine, mianserin, or fluoxetine yielded inconsistent results across efficacy outcomes. Controlled-release paroxetine was the only antidepressant with significantly fewer dropouts due to adverse events than immediate-release paroxetine (RD: 5% [95% CI = 0.1 to 11]).

CONCLUSIONS
There were no significant and valid differences between paroxetine and other antidepressants to suggest that multiple modes of action improve clinical outcomes.


The phenomenon of coal cake collapse is often caused by the unstable operation of the elastic cam in a large coal cake tamper. Aiming at this problem, the mechanical characteristics of the composite rubber elements during cam rotation are studied. A rubber piecewise-function constitutive model is established based on phenomenological theory, and different rubber constitutive model coefficients are obtained according to rubber test data. A contact simulation model between the elastic cam and the tamping hammer friction plate is established to obtain the stress–strain law of the composite rubber elements and the pressure-displacement curve of the elastic cam. The stiffness test platform of the elastic cam is designed, and the differences in results between the test and the simulation are discussed. The results show that the stress–strain curve of rubber has a nonlinear increasing trend and the error between the proposed piecewise function and the test value is less than 2%. As the cam displacement increases from 1 mm to 10 mm, the cam pressure increases from 7715 N to 40,000 N. The simulation results of the rubber stress–strain relationship using the piecewise-function constitutive model are closer to the test data than the simulation results using the elastic modulus as a constant, and the error is less than 6.18%.


In contemporary design research and practice, food is often seen as a problem to be fixed. Designers in the corporate startup realm as well as in academic HFI (Human-Food Interaction) have proposed various techno-solutions to curb complex food system issues such as malnutrition and environmental unsustainability. Quantified diet trackers, 'smart' kitchenware, food sharing apps and similar digital food technologies present opportunities for efficient food practices but also challenges to human-food relationship and social food traditions. The Parlour of Futures project reflects on these contradictions and addresses the growing trend of food-technology innovation through the lens of Speculative and Critical Design (SCD). The project takes the form of a traditional Tarot parlour where participants explore possible food-tech futures as prophecies. Through a bespoke Food Tarot cards deck presenting speculative food practices such as Monsanta[n]ism, Gut Gardening, or Turing Foodism, the project provokes playful food-tech imaginaries and future food scenarios. We discuss the opportunities of SCD in nurturing reflective food design and research, and invite OzCHI attendees to contribute their future food ideas during the Parlour demo session.


Forested wetlands provide ecosystem services and often support elevated levels of biodiversity and rare species. However, forested wetlands are understudied and face threats such as logging and land conversion. Epiphytic lichens are abundant in forested wetlands and may be useful to help delineate microhabitats across wetland–upland gradients. We investigated epiphytic macrolichen richness, diversity, and community composition in 15 sites in the Avalon Forest Ecoregion, Newfoundland, Canada. Within each site, we set up three parallel 40 m transects in (i) the forested wetland, (ii) the ecotone, and (iii) the upland forest. Along each transect, we selected five balsam fir (Abies balsamea (L.) Mill.) trees 10 m apart and surveyed for macrolichens on the lower bole. We collected data on tree height and tree diameter at breast height, which differed significantly among forest types. We also collected data on tree age and canopy cover, which did not differ significantly among forest types. Contrary to hypotheses suggesting that biodiversity is highest in ecotones, we found that mean macrolichen richness was significantly higher in wetlands, lower in the ecotones, and lowest in upland forests, and macrolichen diversity followed a similar pattern but with no significant difference among groups. Macrolichen community composition significantly differed among wetlands, ecotones, and upland forests. A lichen of conservation concern, Erioderma pedicellatum (Hue) P.M. Jørg., was detected primarily in forested wetlands, highlighting wetlands as key habitats for rare epiphytic macrolichens.


Microsimulation modelling of households is an area of research which has seen rapid advances in Australia over recent years, with these models being increasingly used for policy analysis and research in government and academic circles. A relativ ly underdeveloped aspect of this modelling work, however, is the matter of how best to establish linkages between microsimulation models of the household sector and macro economic forecasting/projection models. These linkages are important, not only for reasons of consistency, but also to take account of macro influences on household behaviour and, indeed, of micro influences on aggregate outcomes. This paper sets out possible forms of linkage between micro and macro models, before describing the recursive technique being implemented at NATSEM to link the labour market module of a dynamic microsimulation model with labour force aggregates.


Total-energy and electronic-structure calculations are presented for a recently proposed dodecahedral cluster of eight titanium and twelve carbon atoms. The calculations were done using density-functional theory and a cluster full-potential linear muffin-tin orbital method which is suited to arbitrary geometries and permits direct evaluation of the forces. As in the C 60 molecule, the atoms form a spherical graphitelike shell with a threefold coordination at all sites. The calculated C-C and Ti-C bond lengths are 2.63 and 3.76 bohrs; the binding energy is 6.6 eV per atom


Fractional radon retention is similar in rats, dogs, and man at equal times after radium injection. Fractional radon retention increases with time after radium deposition. This is attributed to increase in mineral density, increase in crystal size, and decrease in diffusion coefficient as bone crystals mature. Fractional radon retention is similar among whole bones in a given animal, but much lower in teeth. A mathematical theory expressing fractional radon retention in terms of mineral density, crystal size, and difiusion coefficient is discussed. (auth)


More than 25 years after its introduction, Model Based Predictive Control (MBPC) is still very much underutilized. It is still perceived by many as too difficult, too expensive, not suitable for non-linear processes etc. Furthermore, many of the installed applications suffer from low utilization, mainly due to over-complex designs and resulting poor operator understanding and acceptance. As a consequence, the industry is by far not exploiting the potential benefits. To help improve this situation is the overall intent of this paper. The first goal is to promote the use of MBPC by raising the awareness of its many benefits and opportunities, by pointing at typical application areas and by describing the mechanism why and how MBPC can deliver superior performance and how to estimate the associated economics. The second objective is to discuss the key factors for successful implementation and use.


Preface Introduction I: The Twofold Character of Machiavelli's Teaching II: Machiavelli's Intention: The Prince III: Machiavelli's Intention: The Discourses IV: Machiavelli's Teaching Notes Index


This Essay responds to thoughtful analyses from Ashley Rubin, Johann Koehler, Geoff Ward, and Fergus McNeill on our book Breaking the Pendulum: The Long Struggle Over Criminal Justice (2017). In particular, we revisit our claim that consensus within the penal field is illusory. Drawing inspiration from our interlocutors, we argue that while recognized actors constantly struggle over the character and scope of criminal justice, they agree (at least implicitly) that certain positions are "unthinkable" and certain actors must remain outside the field. This "conflictual consensus" limits radical transformations of criminal justice. Our revised perspective encourages scholars to analyze how marginal positions and actors become part of the field, as well as the effects they produce while trying to reshape its boundaries. We conclude by sketching out how scholars have extended and revised the agonistic perspective we advance in Breaking the Pendulum and where we might turn next.


In this paper, working in a Friedman-Lemaitre-Robertson-Walker (FLRW), first, in the flat case, we recover the generalized Friedman equation of Quantum Loop cosmology, and therefore the cosmological bounce, in the framework of modified teleparallel gravity $f(T)$-model, $T$ being the torsion scalar introduced in teleparallel gravity approach, without invoking unconventional exotic matter. Furthermore we study the associated perturbations again in a flat FLRW space-time. Then, we generalize the results to the curved FLRW space-time, where some issues related to the choice of tetrad exist, by using an appropriate formulation. In this context, the results of Born-Infeld model are also investigated.


Pelvic fractures are usually the result of high energy blunt trauma and are commonly associated with several other injuries, leaving patients with pelvic fractures at risk of significant complications and mortality.1, 2 In recent years, the incidence of pelvic trauma in female patients has been increasing, although the rate is still lower than that of male patients.1 It has been suggested that gender plays a significant role in survival and complications after trauma and sepsis.3 The reasons postulated for these observed differences between male and female patients are based on both the beneficial effects of the female hormone estrogen and the harmful effects of the male hormone testosterone.3, 4 Human clinical studies, however, have resulted in mixed and conflicting observations when compared with the findings of animal models and some have found better outcomes in male trauma patients.4 The aim of this study was to identify differences and/or similarities in outcome, major complications, and characteristics of pelvic trauma among both male and female patients. First, we wanted to compare several critical parameters between male and female patients with pelvic fracture treated at our American College of Surgeons Level I regional trauma center. Second, using a multivariate linear regression model, we wished to draw conclusions on gender's effect on the outcome of pelvic fracture. This Atlantic Health Institutional Review Board–approved retrospective cohort study included all trauma patients who were hospitalized between January 1, 2005, and June 30, 2006, for pelvic fracture. Data on age, mechanism of injury, Injury Severity Score (ISS), type of pelvic fracture, intensive care unit (ICU) length of stay, hospital length of stay (LOS), ventilator days, admission prothrombin time, transfusion of blood products, pneumonia, other infections, development of deep venous thrombosis, development of pulmonary embolism, solid organ injuries, thoracic injuries, other long bone fractures, operations, and death were collected. Pneumonia was defined by the presence of fever, leukocytosis (leukocyte count >12,000/mm), infiltrate on chest radiograph, and positive sputum cultures. Other infections included urinary tract infections (positive urinary cultures) and blood borne infections (characterized by positive blood cultures). Male and female subgroups of patients were compared using the odds ratio analysis, Mann-Whitney U test, chi-squared test, or unpaired t test. A value of P < 0.05 was considered significant. A total of 111 patients with pelvic fracture were identified at our hospital during the study's 1.5 year period. Of the 111 patients, 37 (33.3%) were women and 74 (67.7%) were men. Our analysis of hospital LOS revealed a significant difference, with male patients spending an average of 18.3 days in the hospital compared with only 8.1 days for women (Table 1). We also compared the number of days spent in the ICU between male and female patients. Among those who were admitted to the ICU (n 4 48; 43 per cent of patients) the median number of ICU days was found to be 4.7 for women and 11.3 for men, a difference found to be significant (Table 1). Table 1 demonstrates the results of comparisons between male and female patients based on a range of clinical factors, complications, and outcomes. A chi-squared analysis of patients receiving operations after pelvic fracture found a statistically significant difference between males and females. A significantly higher percentage of males (67.6%; 50 out of 74) required surgical intervention than females (43.2%; 16 out of 37), with a P value of 0.014. Since inflammation and, more specifically, pneumonia is a very serious complication after injury and trauma with a significant Presented as a poster at the ACS Clinical Congress September 30-October 4, 2012, Chicago, IL. Address correspondence and reprint requests to Zoltan H. Nemeth, M.D., Ph.D., Department of Surgery, Morristown Medical Center, 100 Madison Avenue, Box No. 88, Morristown, NJ 07962. E-mail: email@example.com.


The Medical Library Association Guide to Developing Consumer Health Collections provides an information resource for all librarians, though the focus is on the novice. It is written in a clear, well-organized style, using practical tips and copious examples to illustrate concepts.


Abstract: National projections indicate that the number of people over 60 years old is expected to increase, bringing with it an increase in the number of people affected by Parkinson's Disease (PD). This makes PD an important public health problem. Therefore, the development of effective approaches for intervention in people with Parkinson's disease needs to be more thoroughly investigated. End-to-end application will make exercising at home more convenient for patients. We can project prescribed exercises and determine whether the patient is completing them correctly. The Flutter app enables patients to register themselves, communicate with specialists over the app, and make virtual appointments. The pose detection library will help us detect angles of the exercises, and determine whether patients are performing them correctly


This paper reviews the factors and criteria for the design of new and the retrofitting of existing dry detention ponds to enhance removal of total suspended solids (TSS) from stormwater. Detention time is discussed as the most important factor affecting TSS removal. Two-stage facilities and multi-level outlet design are important means of enhancing TSS removal in dry ponds. Two dry ponds within the city of Edmonton were selected to evaluate their TSS removal. The level of expected TSS removal is low owing to the relatively short detention times for both ponds. Methods for retrofitting the dry ponds to enhance TSS removal are discussed.Key words: dry pond, stormwater, TSS removal, detention time, retrofitting.


Mediation Analysis of the Efficacy of a Training and Technical Assistance Implementation Strategy on Intention to Implement a Couple-based HIV/STI Prevention Intervention