Winter is turning to Spring and a lot is going on in the world of general practice. A feast to digest: The NHS Long Term Plan, the RCGP Future vision of general practice, the Premises review and the Partnership review. I want to look at how we can thrive during this period of upheaval, but first a committee update. Your AiT Committee brings together fellow trainees from all four nations of the United Kingdom. Committee members represent your interests within the RCGP and with outside organisations. All committee members give their time on a voluntary basis and our core mission is to maintain the highest standards of training to prepare us for general practice. Your committee is dedicated to improving your training experience. For example, we are working closely with interested parties to improve GP trainee inductions, to hit the ground running and feel connected with the wider GP community; we are working with stakeholders to overhaul the trainee ePortfolio and make it work for us; we are closely involved in the Future vision of general practice campaign to conceptualise where we want the profession to be in 2030 and then formulate how to get there. On behalf of the committee, I must thank all trainees who have engaged and generously given time to the focus groups and surveys linked to these projects. The fruits of these labours will be visible later this year. And a quick plug – it is not too early to be thinking about the RCGP annual conference in October 2019. It is returning to the Liverpool Docks after 2 years. Take this opportunity to see the excellence in primary care and be inspired. Present your work and connect with the wider GP community. There will be AiT/ First5 themed events running throughout, including socials. Most faculties have bursaries for AiTs. I hope to see you there. Now back to thriving during training. Our training should not be about just surviving until qualification. We should all be thriving, not just during training, but afterwards too. However, something is not right when 5 years after qualifying around 40% of GPs no longer work substantively in the NHS. Work is ongoing both within the college and the wider NHS to address this under the 'wellbeing' umbrella. Personally, I think we should care for ourselves better, so we can care better for others, and the systems we work in should help us achieve this. We will not last long in this profession if we limit our aspiration to just coping. That's no way to live and leads to burn out. Limited aspirations impact on us, but also on those we care about most and our patients. I strongly encourage all trainees to engage and be part of the conversation about this and other matters. If you want to get involved contact your local AiT representative and local faculty. Looking further ahead, if you would like to be a representative and you can commit the time, put yourself forward at the elections when they open later this year. The landscape of general practice is changing. Through all the uncertainty, there will be opportunity and the future will always be ours to make. To leave you with a final thought from Confucius – 'Those who think they can and those who think they can't, are both usually right'.


The paper mainly concerns: first, the US understanding of India and its benefits in South Asia after the Second World War; second, the development of US-India relations from India's independence in 1947 to 1960s. In obedience to the US global strategy, the US India policy changed with its immediate interests and international situation. The result was that the US India policy inevitably took intervention and withdrawal by turns, and both of them were short-sighted.


The zero-temperature magnetoconductivity of just-metallic Si:P scales with magnetic field {ital H} and dopant concentration {ital n} lying on a single universal curve: {sigma}(n,H)/{sigma}(n,0)=G[H{sup {minus}{delta}}{Delta}n] with a magnetic-field crossover exponent {delta}{approx}2. We note that Si:P, Si:B, and Si:As all have unusually large crossover exponents near 2, and suggest that this anomalously weak response to a magnetic field, {Delta}n{sub c}{proportional_to}H{sup {delta}}, is a common feature of uncompensated doped semiconductors. {copyright} {ital 1998} {ital The American Physical Society}


AbstractThe large-strain consolidation behavior of a uranium tailings storage facility was investigated by analyzing survey data (bathymetric and topographic) from 1996 to 2008, laboratory testing of the mill tailings using a consolidation test system, and history matching of the deposited tailings using numerical modeling. The average cumulative consolidated height in the Deilmann Tailings Management Facility (DTMF) can be divided into four distinct stages: (1) rapid increase of 13  m/year from 1996 to 1999, (2) steady height increase of 2.5  m/year over the next 3 years, (3) relatively large height increase of approximately 7  m/year from 2002 to 2005, and (4) a steady height increase of 3  m/year over the next 3 years. During the large-strain consolidation test of the investigated mill tailings (σ′ of 0.3–8 kPa), the void ratio decreased from 5.8 to 3.3 and the solids content increased from 32 to 46%. The vertical hydraulic conductivity was found to range from 6×10−7 to 1×10−7  m/s. The numerical model...


Objective:To observe the protective action of cordyceps polysaccharides on immunological liver injury in mice model and its mechanism.Methods:An immunological liver injury in mice model was induced by administration of lipopolysaaccharide following injection of BCG vaccine into mice for 12 days.ALT,AST levels in serum,the activity of SOD and the concentration of MDA in liver homogenates were examined,TNF-α and IL-1 were assayed by ELISA and the liver pathology was observed.Results:The experiment showed that the cordyceps polysaccharides(125,250,500 mg/kg,ig)could reduce the rising ALT,AST levels in serum of mice with immunological liver injury induced by BCG+LPS,inhabit the rising MDA and enhance the activity of SOD,decrease obviously TNF-α,IL-1 in liver homogenates and the pathology cut section also showed significantly protective effect.Conclusion:Cordyceps polysaccharides has protective effect on immunological liver injury in mice.Its mechanism is possibly related to decrease TNF-α,IL-1 in liver homogenates and its equilibrium on cytokine production.


Abstract : Complex disorder associated with significant co-morbidity, disability, and impairment of daily living following exposure to a traumatic event Diagnosis includes: (1) Event; (2) Reaction; (3) Symptoms; (4) Impairment; (5) Time course Symptoms fall into three clusters: Intrusive recollection of event in some way Avoidance of reminders of the event or numbing Hyper-aroused state.


The theoretical finding of composite disk structures around compact objects (e.g. black holes) and recent experimental observations indicate that highly coherent and dynamically important magnetic field configurations exist in the core of these plasma structures. Coherent configurations involving closed magnetic surfaces provide a means to resolve the 'accretion paradox' for a magnetized disk while the formation of jets emitted in the close vicinity of the compact object is related to these configurations. The absence of vigorous accretion activity in the presence of black holes in old galaxies can be attributed to the loss of the surrounding coherent magnetic configurations during their history. The relevant dynamics include axisymmetric (ballooning) modes as well as tridimensional spirals which can be excited from disks with a 'seed' magnetic field, under the effects of differential rotation and of the vertical plasma pressure gradient. The properties of these spirals are strongly dependent on their vertical structure. Axisymmetric modes can produce vertical flows of thermal energy and particles in opposing directions that can be connected to the winds emanating from disks in active galactic nuclei (AGNs). A similarity to the effects of temperature gradient driven modes in magnetically confined laboratory plasmas is pointed out. Spiral modes that are oscillatory in time and in the radial direction can produce transport of angular momentum toward the outer region of the disk structure, a necessary process for the occurrence of accretion. The excitation of radially localized density spirals co-rotating with the plasma, at a distance related to the Schwartzchild radius RS = 2GM*/c2, is proposed as the explanation for high frequency quasiperiodic oscillations (HFQPOs) of non-thermal x-ray emission from compact objects.


Respiratory syncytial virus (RSV) is an increasingly common cause of respiratory illness in adult non‐immunocompromised patients. Oral ribavirin was reported to improve outcomes of RSV infection in immunocompromised patients. This study aimed to determine the outcomes of non‐immunocompromised patients hospitalized with RSV‐associated acute respiratory illnesses (RSV‐ARI), the factors independently associated with the outcomes and the effect of oral ribavirin treatment.


The austenitic high-nitrogen (AHNS) and high-interstitial steels (AHIS) with more than 0.6 weight-% N allow for a yield strength above 1.1 GPa and a tensile strength above 1.5 GPa by maintaining an elongation to fracture markedly above 30%. These steels gain their prominent mechanical properties from the fact that at the chosen sum of C+N and C/N-ratios, the concentration of free electrons is higher compared to that of other steels. Thus, the capacity to dissipate plastic work under monotonic tensile loading is unique. Now, the fatigue limit of austenitic steels in general is mainly governed by the sum of interstitials and should be further improved by cold working. Unfortunately, this is not the case for the AHNS and AHIS and is in contrast to the classical CrNiC- or CrMnC-steels. Thus, tensile and fatigue tests of cold-worked samples were conducted and analyzed by scanning- and transmission-electron microscopy. This paper tries to elucidate the metallurgical reasons, as well as the material engineering aspects, of such peculiar behavior of AHNS and AHIS.


Embodiment of the present invention provides a method and apparatus for event handling tasks. The method includes establishing a function key event for the task, and the task is added to the function keys corresponding to the event status items in the status bar; when the monitored operation of the function keys, function keys corresponding to functions performed in the status item. Event task processing method and apparatus according to an embodiment of the present invention, the task of improving process efficiency and the event viewer.


Hybrid moulding (HM) is one of the recent advancements in the mould-making process, especially for preparing replicas of plastic components with tailor-made properties. This study highlights the development of a mathematical model (based upon dimensionless analysis) for obtaining the desired surface finish (SF)/Ra of a chip-set case prepared by HM. The input process parameters of HM, namely, de-mould temperature, harder: softener mixing ratio, and type of material have been judiciously selected for understanding the mechanism of Ra in HM. This study highlights the main effects of these input process parameters on SF/Ra as mathematical models.


Chapter 1.The Case Study Approach. Chapter 2. Inclusive School Governance and Special Education. Chapter 3. Identification and Placement Issues in Special Education. Chapter 4. Conflict in Special Education. Chapter 5. Program Evaluation in Special Education. Chapter 6. Fiscal Issues in Special Education. Chapter 7. Personnel Issues in Special Education. Chapter 8. Transportation Issues in Special Education. Chapter 9. School Reform in Special Education. Chapter 10. Discipline in Special Education. Appendix A. Questions and Reflections. Appendix B. Matrix of Primary and Secondary Issues for Case Studies. References.


Objective: The interaction of CD40-CD40 ligand (CD40L; CD154) plays a central role in inflammatory disease. However, there are conflicting reports about its contribution to atherogenesis. Some of this controversy may arise from cell type-specific signaling initiated by CD40 ligation. To further clarify the cell-specific roles of CD40-associated inflammation in the context of atherosclerosis, we generated tamoxifen-inducible smooth muscle cell (SMC)-specific CD40 (Smmc-Cre + CD40 fl/fl ) and endothelial cell (EC)-specific CD40 deficient mice (Bmx-Cre + CD40 fl/fl ) on an ApoE-deficient background (iSMC-CD40 -/- /Apoe -/- and iEC-CD40 -/- /Apoe -/- , respectively). Methods & Results: All mice (including CD40 fl/fl /Apoe -/- controls) received tamoxifen at 9 weeks and consumed chow diet for additional 20 weeks to induce slow progression of atherosclerosis. Although less leukocytes adhered to the endothelium in iEC-CD40 -/- /ApoE -/- mice as assessed by intravital microscopy, the size of atherosclerotic plaques did not differ compared with respective controls. In contrast, iSMC-CD40 -/- /ApoE -/- mice exhibited decreased atherosclerotic plaque size in the aortic root. iSMC-CD40 -/- /ApoE -/- mice showed a significant increase of circulating granulocytes and monocytes and a shift to more Ly6C low monocytes and regulatory T cells. Notably, iSMC-CD40 -/- /ApoE -/- mice displayed substantial splenomegaly. CD11b + leukocytes in the peritoneum were decreased suggesting impaired capacity of monocytes and granulocytes to migrate. Conclusion: We studied the role of CD40 in non-hematopoietic vascular cells on atherosclerosis: Whereas EC-specific CD40 deficiency does not affect atherogenesis, SMC-specific deletion of CD40 attenuates atherogenesis, likely by impaired infiltration into the arterial wall. However, further mechanistic studies are ongoing to elucidate the SMC-specific role of CD40 on inflammation and atherosclerosis.


The research presents a fuzzy control method for DC servomotor control system, which is two inputs and one output fuzzy control model. In the model, the output is motor velocity or motor move position, and the two inputs are error and error change for velocity or position. The control system hardware architecture is consists of PWM module, encoder module, DC motor drive module, and DSP control module. The control module for DC motor is embedded system by DSP, and the velocity control and position control are work by DSP program with fuzzy logical control. The DC servomotor move control is realized by the DSP embedded system with the research fuzzy logical control method.


In 2011, the World Bank commenced the process of a comprehensive review  and reform of Bank procurement policies and procedures, the first of its kind in the history of the Bank. The significance of the proposed reforms cannot be understated and they evince a step-change in the way the Bank has conceptualized and conducted procurement since its inception. The purpose of the reforms are to ensure that the Bank's procurement is fit for its purpose, is flexible, is in line with the modern practice of public procurement and can assist Borrowers to deliver on their developmental objectives. This paper examines the salient features of the reform agenda and highlights the implications of the reforms for African borrowers. It will be seen that the Bank desires to undertake a central leadership role in global public procurement and that it is putting sustainability at the heart of its reforms. It will also be seen that the Bank intends to provide more assistance to building the procurement capacity in its Borrowers to partly address the moral hazard that arises in Bank projects.


This document defines the scope and set of requirements for the
Security Automation and Continuous Monitoring (SACM) architecture,
data model, and transfer protocols. The requirements and scope are
based on the agreed-upon use cases described in RFC 7632.


Discusses the progress and the evolution of the development of range sensing techniques at the NRC laboratories. Essentially a 3D imaging project at the beginning, it has evolved to a new media project which requires the development of new tools for 3D modeling, editing, database searching and visualization. Generic applications related to documentation, inspection, target tracking and visual communication will be discussed.


This paper reports the application of the Hilbert-Huang Transform (HHT) to the dynamic characterization of rail vibration induced by surface pits. A different acceleration signal of rail induced by surface pits is adaptively decomposed into Intrinsic Mode Functions (IMFs) through the use of Empirical Mode Decomposition (EMD) methods. Based on the EMD, the associated time-frequency-energy distribution, i.e., the Hilbert spectrum is obtained for the analysis of the rail vibration signal and subsequent identification of its corresponding energy characteristics. In order to assess the effectiveness of the approach, the results obtained using the HHT are compared with those from wavelet based methods. It is found that the extracted energy characteristics give a good indication of the dynamic state of raU high frequency vibration and thus can be used for rail pits recognition. The proposed method is a useful tool for the in depth understanding and subsequent quantitative characterization of rail high frequency vibration.


The aerodynamic characteristics of an advanced lifting ejector system incorporated into a full-scale, powered, fighter aircraft model were measured at statically and at transition airspeeds in the 40- by 80- and 80- by 120-Foot Wind Tunnels at NASA-Ames. The ejector system was installed in an ejector-lift/vectored thrust STOVL (Short Take-Off Vertical Landing) fighter aircraft configuration. Ejector thrust augmentation ratios approaching 1.6 were demonstrated during static testing. Changes in the internal aerodynamics and exit flow conditions of the ejector ducts are presented for a variety of wind-off and forward-flight test conditions. Wind-on test results indicate a small decrease in ejector performance and increase in exit flow nonuniformity with forward speed. Simulated ejector start-up at high speed, nose-up attitudes caused only small effects on overall vehicle forces and moments despite the fact that the ejector inlet flow was found to induce large regions of negative pressure on the upper surface of the wing apex adjacent to the inlets.


Drawing upon the framework of Sectoral Innovation Systems, this study explores the patterns of technological innovation among small and medium-sized wooden furniture manufacturers in Malaysia from two perspectives viz., sources of knowledge and technology and capability of forming linkages. The empirical evidence for the study was derived from 70 survey respondents. The wooden furniture industry in Malaysia warrants an in-depth analysis as it is among the very few full-fledged home-grown industry that has successfully penetrated the global market. The study reveals that the majority of the innovative enterprises are mainly young home grown SMEs. They are centred on business-driven activities. Clients, customers and suppliers are the key partners for co-operation in innovation, as well as sources of technology and knowledge.


Listeners can make consistent judgments regarding the tallness of speakers [Rendall etal., J. Exp. Psych: Human Percep. Perform. 33, 1208 (2007)]. These judgments are informed by the f0 and formant frequencies (FFs) of a speaker's voice. However, FFs are also cues to vowel identity, such that a small speaker producing an /u/ might have lower average FFs than a larger speaker producing an /ae/. Do listeners use absolute FFs to judge speaker tallness, or do they "correct" for phonetic identity and consider the FFs of a vowel relative to those expected for that category? To test this, a series of synthetic vowels (/i ae u/) with different FF scalings and different numbers of formants (2–5) were created. These scalings were intended to replicate speakers of different vocal tract lengths (i.e., sizes). Participants were presented with pairs of vowels and asked to indicate which vowel sounded like it had been produced by a taller speaker. Results indicate that listeners consider both absolute and phonetically "co...


Using tools from Lorentzian geometry (arising from the presence of the Fefferman metric) we prove a Takahashi type theorem (for a class of pseudohermitian immersions covered by connection-preserving equivariant immersions among the total spaces of the canonical circle bundles) thus relating the geometry of a pseudohermitian immersion from a strictly pseudoconvex CR manifold M into an odd dimensional sphere, to the spectrum of the sublaplacian on M .


Through elaborating the cross-disciplined connotation and its practical signification on research,this paper analyzes the necessity and importance in the cultivation of cross-disciplined postgraduate students' innovative ability,which will provide theoretical research fundamentals for the pattern of cross-disciplined postgraduate students' cultivation so as to discuss how to construct the system of united cross-disciplined cultivation.


Copper oxide nanoparticle-doped silver phosphate glasses were prepared by the melt quench technique. X-ray powder diffraction, Fourier transform infrared spectroscopy and scanning electron microsco...


The globalization era has made business competition becomes more competitive, it forces the company to increase their innovation to the business management and competition strategy. Pharmaceutical and cosmetics sector manufacturing companies are selected since this sector has a wide scope so many capitals are involved including intellectual capital primarily in Human Capital, Structural Capital, and Customer Capital. This research is meant to prove empirically the influence of VAIC, Leverage, and Size to the disclosure of intellectual capital. The independent variables which have been applied in this research is performance of intellectual capital which is measured by using Value Added Intellectual Coefficient (VAIC), size, and leverage method. The dependent variable of this research is disclosure of intellectual capital (ICD). The analysis method has been carried out by using panel data. Based on the result of the test which is the performance of intellectual capital (VAIC) does not have any influence to the variable of intellectual capital. The leverage variable does not have any influence to the variable of disclosure of intellectual capital. The Size variable has an influence to the variable of intellectual capital. Keywords: Intellectual capital, Leverage, Size, Disclosure of Intellectual Capital.


A solitary malignant schwannoma with glandular differentiation occurred in the forearm of a 54‐year‐old man. The patient displayed no stigmata of von Recklinghausen's neurofibromatosis. He did well after conservative surgery and there are no signs of recurrence 5 years after operation. The rarity of the tumour and the unusually long survival are points of interest. The histogenesis of the glandular component is discussed.


A simple, accurate, precise, economical and reproducible UV spectrophotometric method has been developed and validated for the simultaneous determination of benzil impurity in phenytoin in synthetic mixture without their prior separation. The method employs formation and solving of simultaneous equation using 221 nm and 264 nm as the two analytical wavelengths. Validation studies are statistically significant as all statistical parameters are within the acceptance range (% COV < 2.0 and SD < 2.0).


For the purposes of this project the Latrobe Valley region is defined as the three local government areas (LGAs) of Latrobe City, Baw Baw and Wellington. The estimated population of this region in 2010 was 162,700 people (KPMG, 2011) up from 146,567 in 2006. Utilising existing data from key reports and research, this briefing report provides a contextual overview for this study by answering the following questions: 1. What has been said about economic diversification in the Latrobe Valley Region (Baw Baw, Latrobe City and Wellington)? 2. Where are the job opportunities (current and projected) in the Latrobe Valley Region and wider Gippsland? 3. What are the conditions for realising these opportunities? Seeks to identify the roles and the skills of workers in industries likely to be impacted by a transition to a low carbon economy.This Briefing Paper aims to answer the following questions with currently available data from key reports and research: Key findings 1. There is a lack of consistency in available reports as to where growth areas are located. 2. There are different understandings about the generation of jobs in the region. 3. There are likely to be very different outcomes depending on whether there is active government intervention or not. 4. The choice of policy approach appears to be either one that is comprehensive and integrated or a series of ad hoc interventions; the outcomes are likely to be different. Implications 1. Policy must be very clear about the approach that is advocated to generate jobs. 2. Decisions should be taken about the focus of intervention. 3. Consideration will need to be given to how the different levels of government and all relevant interest groups are involved in the process of transition. 4. Attention should be given to encouraging an agreed approach for the Latrobe Valley region, involving a range of social actors (e.g. employers, unions, local government, community organisations) across the three LGAs.


Oz Purpose: We aimed to evaluate retrospectively the results of treatment of patients with chronic hepatitis C in our clinic. Material and Methods: We evaluated the treatment results of 109 patients who treated with the diagnosis of chronic hepatitis C between the years of 2003-2015 in our clinic. Results: The 52.3% of the patients were male, the mean age was 52.3, mean ALT value 58.3 IU/ml and average HCV-RNA levels was 3,7x106 IU/ml. Previous treatment history in 47 patients (43%) was available. Eigthy-one patients (74.3%) received treatment of pegylated interferon and ribavirin and 28 patients(25.7%) received combination of pegylated interferon, ribavirin and telaprevir. Early virologic response were obtained in 99(90.8%) of 109 patients. Sustained virologic response was more higher in patients who achieved early virologic response. Sustained viralogic response in group of PegIFN/R was %74.1 and in group of PegIFN/R/T was 76.9%. At least one of complaints as rash, itching, taste disorder and anorectal pain were observed in PegIFN/R/T group. All patients had anemia as the most common hematologic side-effect. Depressive symptoms were observed in 19% of patients. Conclusion: With available treatment options in our country, patients who can not be achieved to SVR rates are available. There is a need for new antiviral drugs that used in the world for the patients infected with genotype 1 who had unsuccessful treatment. Amac: Klinigimizde kronik hepatit C nedeni ile izlenen


This paper presents a novel method for facial feature extraction from video. Face recognition from video has been extensively studied in recent years. Intuitively, video provides more information than a single image. When a face is partially occluded, handling the occluded part of the face is an especially challenging task. The present research work proposes the method to recognize a face from video based on face patches. First, face patches are cropped from the video frame by frame [4]. Then, face patches are to be matched to an overall face model and stitched together. By accumulating the patches, a reconstructed face is to be built which is used in recognition. Then testing has to be done in two parts. In the first part, a still face database is to be used by randomly occluding parts of the face and using the remaining face patches in recognition. In the second part, the image is to be tested on video sequences. Related Work Automated face recognition is a relatively new concept. Developed in the 1960's[1], the first semi-automated system for face recognition required the administrator to locate features(such as eyes, ears, nose, and mouth) on the photographs before it calculated distances and ratios to a common reference point, which were then compared to a reference data[2].


Four new species are assigned to Vogelgnathus Norby and Rexroad because of the close similarity of their Pb and ramiform elements to those of the type species, V. campbelli (Rexroad). Recognition of the four new species requires that the generic diagnosis, based almost exclusively on the morphology of V. campbelli, be modified, chiefly to accommodate greater variation in Pa element morphology. Vogelgnathus dhindsai n. sp., V. gladiolus n. sp., V. kyphus n. sp., and V. pesaquidi n. sp. all possess abbreviated, carminiscaphate Pa elements. Spathognathodus postcampbelli Austin and Husri is reassigned to the genus. The origins of Vogelgnathus are uncertain but V. gladiolus first appeared in the early Viséan and gave rise to V. pesaquidi. The latter species appears to represent the rootstock from which V. kyphus, V. campbelli, and V. dhindsai evolved. Vogelgnathus postcampbelli evolved from V. campbelli during the late Viséan. Vogelgnathus campbelli and, to a lesser extent, V. postcampbelli have a wide geographic distribution; the four new species, however, are currently known only from Atlantic Canada, northern England, and southwest Scotland.


Providing a secondary frictional material between a primary frictional material and a backing plate for use in a clutch or brake system having a reaction member which operates in an oil bath, whereupon the consumption of the primary frictional material through contact with the reaction member allows contact between the secondary frictional material and the reaction member. The secondary frictional material is of a composition such that upon motion contact with a reaction member an audible sound is produced.


The multiple fracture, apparently without warning, of the crankshaft of one of a pair of medium-speed propulsion engines in a modern cargo ship in mid-Atlantic led to a programme of tests, involving many alignment measurements, chiefly on a sister ship. The damage to the engine is reviewed and an account is given of the investigation into the cause of failure. The measured values of alignment are recorded, together with changes of alignment due to temperature variations of the machinery, the lubricating oil, and the cooling water, and to cargo loading and distribution. Conclusions are stated and a set of rules, which have been supported by subsequent experience, are postulated.


Through the transformation of basic equipment, this paper realizes the control of the stable resin content of prepreg yarn while fully maintaining the impregnation. Through the research on the resin curing process, resin content, and aging degree of the resin system during the prepreg manufacturing process, the resin content and aging process of the prepreg corresponding to the optimal tensile performance of the NOL ring were determined, and a high-tension winding method was obtained. The prepreg yarn MP01/HF30F/28 prepreg yarn. During the manufacturing process of wound gas cylinders, through the research on the curing system and layup design, the burst strength of dry wound gas cylinders reached 68.5MPa, and the corresponding fiber performance conversion rate was 81.2%, which exceeded that of wet-sprayed wet-spun fibers. The blasting performance conversion rate of wound gas cylinders is 19.8%. Thus opening up a new application method of wet-jet wet-spun carbon fiber in the field of winding.


Address given by Edward White before the Texas Surgical Society as its president, about his experiences in the field of medicine as well as some advice to young professionals.


Membership Duration Aware-ALM (MDA-ALM) protocol was suggested to decrease node rejoin ratio in application-level multicast networks, it depends on the announcement of the expected membership duration for each new user in order to build a stable and efficient tree. Although the performance of (MDA-ALM) protocol is good, but it is based on membership duration parameter and this makes it more sensitive for cheating and non-cooperative nodes. The main goal for the cheating nodes is to improve their position in the tree by trying to get the nearest position to the source node and to avoid having any children in order to relieve its load by manipulating the membership duration information. Our research aims to find the best solution to detect the cheating nodes. The simulation results prove that the proposed scheme detects effectively the cheating nodes. Furthermore, we simulate two schemes that we proposed to cancel cheating in order to choose the best between them.


The Feature of center manifolds is discussed.The method of the solution the approximate center manifolds is declared,and when the problem of bifurcations is discussed the method of reduced order of differential equation is declared by the feature of stability of structure of equilibrum point's neighbourhood.


Matrices coming from elliptic Partial Differential Equations have been shown to have a low4 rank property: well defined off-diagonal blocks of their Schur complements can be approximated by low-rank 5 products and this property can be efficiently exploited in multifrontal solvers to provide a substantial reduction 6 of their complexity. Among the possible low-rank formats, the Block Low-Rank format (BLR) is easy to use 7 in a general purpose multifrontal solver and has been shown to provide significant gains compared to full-rank 8 on practical applications. However, unlike hierarchical formats, such as H and HSS, its theoretical complexity 9 was unknown. In this paper, we extend the theoretical work done on hierarchical matrices in order to compute 10 the theoretical complexity of the BLR multifrontal factorization. We then present several variants of the BLR 11 multifrontal factorization, depending on the strategies used to perform the updates in the frontal matrices and 12 on the constraints on how numerical pivoting is handled. We show how these variants can further reduce the 13 complexity of the factorization. In the best case (3D, constant ranks), we obtain a complexity of the order of 14 O(n4/3). We provide an experimental study with numerical results to support our complexity bounds. 15


This article aims to interrogate law's ambivalent relationship with urban space. It deals with the paradoxical relation between law and the city, visibility and invisibility, materiality and abstraction, and polis and metropolis. It builds on previous work on the lawscape, namely the priority of invitation by law or the city to be conditioned by the other, and expands this line of thought towards a more tangible understanding of visibility and its mutual constitution with invisibility. We believe that spatialisation is a relevant avenue for law's (re)conceptualisation because it moves away from a description of humanism based on the universality of subjectivity, and paves the way for a particularised and material description of law's multiplicity that specifically addresses law's social positioning. This inevitably leads to a dematerialisation of space and the reinstatement of circularity between concreteness and abstraction. Inspired by some of the themes addressed by the contributors in this issue, we begin constructing a vocabulary of lawscaping, where law and urban space are brought together in an epistemological embrace that targets and eventually questions the solipsistic way in which the two of them have been conceptualised so far.


Plantar pressure images carry crucial information about plantar diseases and deformations and allow inferring about postural issues. It is important to simplify and maximize the information acquired in plantar pressure measurements in order to help the study of plantar pressure related pathologies. Aiming to achieve such need, the alignment, i.e. the registration, of plantar pressure images has been studied. The alignment of two images can be described as the process of transforming one image in order to correspondent areas or features are optimally overlapped with the ones in a second image. In this work, sequences of images acquired during steps of individuals were aligned both in space and time. The spatial alignment is performed between peak pressure representative images of each sequence. Thus, a "moving" image is mapped into the "fixed" image by a rigid geometric transformation. The principal axes of both images are found and then the angle between them is calculated. The translation is determined by the differences between image centroids after rotation. An optimization algorithm is used in order to improve the estimated values. After the spatial alignment, the sampling frequency of the sequences is increased by interpolation of intermediate images in order to obtain more continuous data. Considering the "expanded" sequences, a cost matrix is built containing the mean standard errors (representing the individual matching cost) between all possible image pairs from both sequences to align. Images with the same index from different sequences may not correspond in time because the same person has different pressure patterns between steps. Consequently, a matching algorithm based on dynamic programming is used to establish the matching of minimum global cost. A polynomial relationship between both sequences is established using polynomial degrees up to 10 degree. The polynomial coefficients are found by the least squares technique. The accuracy of the solution developed was accessed through the mean standard error (MSE) calculation between the aligned and the template sequences. Additionally, control deformations were applied in order to find the residual errors between the original and re-aligned sequences. The spatio-temporal solution developed obtained high accuracy in the intra-subject spatiotemporal alignment when using high degree polynomials (p<0.001) up to 10th degree. Such finding is confirmed both by the mean MSE values and the residual errors. In addition, the temporal alignment algorithm presented fast computational speed. Another finding points to the fact that only a small increase in the sampling frequency influences the accuracy of the spatio-temporal alignment.


Objective To evaluate the effectiveness of health training for family health-care assistants for patients with diabetes mellitus in community health control.Methods The prospective self-control study was conducted in 220 diabetes mellitus patients accepted the family health-care assistants' health training for themselves or their attendants.The ability of self-management,degree of mastering diabetes-related knowledge,and results of some biomedical measures were compared between the before and 6 months after implementation of the health training.The effectiveness of health training for family health-care assistants for patients with diabetes mellitus in community health control was evaluated.Results After the implementation the health training,we divided the two groups based on the effect of health training.The patients' abilities of self-management and the level of mastering diabetes-related knowledge was improved(P 0.05).In the positive effect group,HbA1c level was decreased(P 0.05) by comparing the before and the after health training(P 0.05);However,the body mass index had no significant changes(P 0.05).Conclusion The family health-care assistants' health training plays an important role in patients with diabetes mellitus in community health control,and we should pay more attention to completing these programs.


The records of 944 children who had been examined by one pediatrician for alleged sexual abuse were analyzed. Sixty-four percent of the females and 34 percent of the males had positive findings suggestive of ano-genital injury. The data indicated that in girls with no evidence of injury, the hymenal opening diameter varied directly with age, but in those with evidence of injury, the opening size could not be correlated with age.


Up to the present, a viscous liquid like as Tororo-aoi are used for manufacture of hand-made paper, and many studies and presentation appeared on this problem as to the purpose of the liquid. It was generally considered that this liquid is mainly required in the process of manufacturing and it has no influence to the quality of the product. However, from my study, it was cleared that this liquid give a bad effect to papers materials remarkably.


The bimolecular decay of the hydroxymethylperoxyl radical in aqueous solution (k = 2.1 x 109 M-1s-1) leads mainly (80%) to one molecule of hydrogen peroxid and to two molecules of formic acid. 2 HOCH2OO· → H2O2 + 2 HCOOH Deuterium kinetic isotope effects show that the decay occurs at room temperature via a short lived (τ < 10-4 s) tetroxid.


Although the presence of the electrocardiographic (ECG) strain pattern has been associated with an increased risk of developing heart failure (HF), the relationship of regression vs. persistence vs. development of new ECG strain to subsequent HF is unclear.


An overview of the water-soluble fractions of biomass and biomass ash (BA) and their significance for solid biofuel application was conducted based on reference peer-reviewed data plus our own inve...


Correction for 'Studies on the crystal structure and arrangement of water in sitagliptin L-tartrate hydrates' by Eszter Tieger et al., CrystEngComm, 2016, 18, 3819–3831.


Reproductive records from 1072 Large White sows (3589 litters) were used to examine the effect of backfat depth (Ed) and live weight (Lw) at selection on first litter and lifetime reproductive performance. The variables investigated included mating age, total piglets born, total bent alive, piglet birth weight, number weaned weaned, piglet weaning weight, weaning to remating period and number of litters produced. Using backfat depth, sows were categorized into three groups: L, 9 to 13 mm; M, 14 to 16 mm; and F, greater than or equal to 17 mm. Ed had no significant effect (P > 0.05) on the measured traits for the sows grouped by fat at first parity. When lifetime reproductive data were analysed, the L group had fewer litters (P < 0.05), and weaned fewer pigs (P < 0.01) than either rite M or F group. The birth weight for piglets from L sows were significantly higher (P < 0.05) than for piglets from the other groups. The data suggest that the reproductive performance of L souls is not as good as that of M or F sows.


In this paper, we start by introducing a novel disk rational Bézier based on parallel projection, whose properties are also discussed. Then applying weighted least squares, multiobjective optimization techniques and constrained quadratic programming, we achieve multi-degree reduction of this kind of disk rational Bézier curve. The paper also gives error estimation and shows some numerical examples to illustrate the validity of theoretical reasoning.


In 1973 I wrote a paper called The topsy-turvy world of "sight" words' (Groff, 1974). I was hopeful at that time that my negatively critical comments about sight words, when published, would be helpful in reforming the thinking of those who believe in this supposed phenomenon.


This article surveys findings on the lasting effects of child sexual abuse on individuals and on the family, child care, education, social service, health care, and legal systems. Child sexual abuse clearly has immediate identifiable effects, consistent symptom patterns, and adverse long-term effects on both boys and girls. It is suspected as the underlying ideology of a number of mental health disorders that have been resistent to treatment, including borderline and multiple personalities. There are, however, difficulties in establishing a linear relationship between sexual abuse in childhood and a specific outcome in adulthood. More work is needed to develop one conceptual model adequate to describe sexual abuse. Since 1976, the incidents of reported child sexual abuse has risen an estimated 27%. The role of reconstituted families in the increased incidents, and the effect of increased awareness of sexual abuse on teachers and other child care providers are discussed. It is recommended that effort be directed to locating the underlying causes of child sexual abuse, so social policy for prevention of child sexual abuse can take accurate aim at the source of the problem. It is necessary that prevention programs directed to children not prevent development of crucial trust. Specific recommendations for future research are made.


With its large, inhomogeneously broadened optical transitions porous silicon offers new, interesting fluorescence line narrowing effects. Cathodic current transfer at lightly doped n‐type porous layers in contact with an aqueous solution exhibits reversible, highly contrasted voltage‐selective quenching of the photoluminescence (QPL) for a voltage variation of only about 500 mV. A spectral blue shift along with a narrowing of the linewidth accompanies the observed strong QPL. It is explained either by a selective saturation or by a selective Auger effect, both due to carrier injection at energies determined by the applied voltage. The electroluminescence (EL) of porous silicon in aqueous persulfate solutions shows a tuning as large as 270 nm for an external bias variation of 0.6 V. The study of the EL behavior as a function of the external voltage and the persulfate ion concentration proves that while the amplitude of the EL is proportional to the intensity of the exchanged current, the spectral position is only determined by the applied voltage. It is explained by the double selectivity of electron and hole injection.


. This article summarizes the arguments and counterarguments within the scientific discussion on the issue of the analytical evaluation of the conflict management efficiency under the conditions of the PJSC AMKR. The main purpose of the research was to develop ways of preventing conflicts in the administrative management. The systematization of the literature sources and approaches to resolving the problem of conflicts in the administrative management has shown that this issue is widely dealt with by both Ukrainian and foreign scientists. The relevance of solving this scientific problem lies in the fact that diagnosing conflicts will make it possible to develop more specific measures to eliminate existing conflicts and prevent new ones from occurring. The methodological basis of the research was general scientific and special methods of cognition. The methods of theoretical generalization, grouping and comparison have been used in the paper. The bibliometric and bibliographic methods were used in identifying problematic issues related to the evaluation of the conflict management efficiency. The methods of concretization, analysis, synthesis, abstraction, and the dialectical method formed the basis for improving the system of conflict handling in the administrative management. The graphical method was used for the visual representation of statistical data. The years 2012 until 2019 were selected as the research period. PJSC ArcelorMittal Kryvyi Rih was selected as the object of the research. The results of the research lie in the fact that the recommendations developed for resolving conflict situations can be used in the practical activities of the company under research. In order to enhance the company's profitability and operational efficiency, the managers of PJSC ArcelorMittal Kryvyi Rih need to demonstrate their professionalism in anticipating, analysing and handling conflicts. The level of relevant knowledge, creative approach, strategic thinking and analysis of the situation by the company's managerial staff are the key components of successful conflict resolution and managerial decision-making. The scientific novelty of the results obtained lies in the development of efficient methodological tools for diagnosing conflicts, which will make it possible to develop more specific measures to eliminate existing conflicts and prevent new ones from occurring.


Presents a technique, named ARON (adaptive region of nonlinearity), that accelerates learning processes through a dynamic adaptation of the error surface. The procedure implements a generalization of the basic McCulloch-Pitts type of neuron which gives to each unit the ability to automatically adapt its operational region according to the requirements of the problem.<<ETX>>


The 2016 Austroads Congestion and Reliability Review (AP-R534-16) measured the levels of congestion across major cities in Australia and New Zealand, assessed the key causes of congestion, and proposed an approach to identifying and assessing congestion interventions and ultimately developing a congestion mitigation roadmap. This report extends on the previous research by capturing key strategies and initiatives Australian and New Zealand road agencies have implemented or are implementing. Specific case studies are detailed in this report to support the knowledge transfer and sharing across the member organisations.


A lthough intraoperative autotransfusion (IAT) became commercially available in the late 1960s, the technology did not gain clinical popularity until the mid-1970s, a time when the risk of viral transmission from allogeneic blood transfusion was of major concern. The value of IAT was quickly recognized in the early to mid 1980s, when 2% of all HIV/ AIDS cases in the United States resulted from blood transfusion, and the risk of viral hepatitis from transfusion was as high as 3% to 10%. The utility of IAT was initially described in patients undergoing cardiac, vascular, and transplant surgery. For these procedures, several early studies demonstrated a 50% reduction in allogeneic blood requirements, with overall cost savings demonstrated when more than 2 or 3 units of transfused blood was required or when surgical blood loss exceeded 700 mL. Not only were costs reduced with IAT, but safety and efficacy were also demonstrated, and the conservation of a scarce supply of blood became possible. IAT was clearly beneficial for patients with rare blood types, those with red blood cell (RBC) alloantibodies, and those who refused allogeneic transfusions for religious reasons. In this issue of TRANSFUSION, Waters and colleagues present the largest series of IAT cases to date, with nearly 20,000 cases performed in a network of 12 hospitals over a 5-year period. By setting a measurement criteria of at least 1 unit equivalent of RBCs returned to the patient in more than half of the patients undergoing a given surgical procedure, the authors have defined which procedures are most appropriate for utilizing IAT. It is no surprise that the greatest yield of return for salvaged blood was seen in patients who were undergoing cardiac, major vascular, and transplant procedures. However, at the other extreme, there were a large number of procedures in which returned blood was typically less than 1 blood unit equivalent. Overall, almost half of the procedures studied (46.5%) failed to meet the criteria for IAT utility ( 1 RBC unit equivalent returned). Although the authors calculated more than $2 million in cost savings from the use of IAT over the 5-year period for the 12 hospitals combined, they concluded that using IAT more selectively would improve overall efficiency. What is novel in the current study is how the high-yield IAT surgical procedures compare to other procedures with a lower yield.The most frequently performed surgeries that did not show clear benefit from IAT were orthopedic (total hip replacement), lumbar spine, and prostate surgeries. In fact, removing these three surgical procedures from the total case mix (from Table 2 of the article) would eliminate 82% (7594 of 9244) of the patients who received less than 1 unit equivalent of returned RBCs. When these three surgical procedures are further analyzed by averaging the ratios of patients receiving 1 unit or more to those receiving less than 1 unit, the resulting ratio is 0.21, indicating that only one out of five of these patients received 1 unit equivalent or more of returned RBCs. The authors appropriately explain that their findings are likely to be institution specific and that other centers should examine their own cases to define which patients would most benefit from IAT. Of course it is sometimes difficult or impossible to predict which patient undergoing a given procedure is going to experience significant intraoperative blood loss, thus making the decision to use IAT sometimes difficult. Certain procedures, such as lumbar spine cases, can represent a wide spectrum of surgical invasiveness and corresponding blood loss. It is somewhat surprising that the study reports using IAT in the "minor" spine cases, such as laminectomy and spinal decompression surgeries, where expected blood loss is relatively small compared to the larger multilevel spine fusions with instrumentation. It was also interesting that even the lumbar spine cases with fusion did not show a consistent benefit from IAT. Depending on the type of spinal fusion, the ratios in the authors' Table 2 demonstrate that only 16% to 46% of these patients received 1 blood unit equivalent or more in returned RBCs. This somewhat low IAT yield may be explained by advanced surgical technique (or skill) that could be specific to the authors' institution, since blood loss can often be dramatic in these cases, depending on the number of spinal disk spaces that are fused and other surgical variables. The authors should be commended for gathering such a large series of cases to define the utility of IAT for the purpose of optimizing case selection. Perhaps the picture would be more complete, however, if additional information was given, such as estimated intraoperative blood loss, or postoperative hemoglobin levels. Of equal importance would be the percentage of patients undergoing a given procedure who were spared from receiving any allogeneic blood component as a result of IAT. This additional information would allow others to better TRANSFUSION 2011;51:2058-2060.


Financial statements describes the performance of corporate management in managing the resources entrusted. In an effort to refine those statements was born the concept of conservatism. The concept of conservatism that will affect the quality of the resulting company's earnings, which can increase or decrease the quality of earnings. Besides that the influence of corporate governance (independent commissioners, institutional ownership, managerial ownership, quality audit) may also affect the quality of a company's earnings. This research aims to examine and analyze the differences in the quality of corporate earnings in the conservative and less conservative, and the influence of corporate governance on the quality of corporate earnings. The data used in the form of annual financial statement data of manufacturing companies listed on the Indonesia Stock Exchange (BEI) in the period 2008-2010. Sources of data in this research is secondary data from the manufacturing company's financial statements published by the BEI in http://www.idx.co.id/ site and also share data on the Indonesian Capital Market Directory (ICMD). The results showed that there is a difference between the quality of earnings (which diproksikan coefficient ERC) and non-corporate conservatism conservatism. Independent Commissioner (KI), Institutional Ownership (Kinst), Managerial Ownership (KM), and Quality Audit (KA) significantly influence the coefficient of ERC.


According to SOLAS 1974,Office Excel was used to program the calculation and verification of the bulk grain vessel's stability.The program has functions of automatic chart searching,interpolation,and simple logical judgment.It is able to determine whether a data item had been processed and to give directly conclusions through the calculation and judgment according to a given conditions.For example,the cargo stowage plan can be changed and adjusted and decision can be made instantly to know if a requirement is met.


Teamwork is an acceptable and structured process used by academics to assess progress in academic modules. Team leaders are usually elected to coordinate team activities required for the successful completion of projects. In the process of teamwork, team members and team leaders alike gain valuable skills that will prepare them for life and the world of work. In addition, management and teamwork are also an engineering programme requirement of the engineering accreditation body. This study reports on team leader interviews conducted on completion of a major project executed in an engineering module in an engineering programme. The research was conducted to investigate the effectiveness of team projects in terms of team member commitment, project execution and the associated skills practised. The research can contribute to the structuring of project teams, measures of fair assessment and improving the quality of team project experience.


Virtual reality technology is a new type of interactive technology by using computer to generate simulation environment.Starting from the concept of virtual reality technology,this article explains the advantages of virtual reality technology and discusses the application of virtual reality technology in practical teaching with an example of multimedia computer virtual labs.


Abstract Referring to medieval conceptions of history modern medievalists currently employ the terms ,,Heilsgeschichte," ,,salvation history," ,,history of salvation," ,,histoire du Salut", or similar ones, whereas the seemingly corresponding term
 historia salutis is extremely rare in the medieval texts: among the Latin Christian authors up to 1200 only two, Petrus Damiani and Rupert of Deutz use it – not often ‐ in their writings. My contribution explores the meaning these authors attach to the term, and takes a
 look at its patristic precedents. Different from the modern concept, the medieval historia salutis does not associate salvation with history as a general process, but with the life and deeds – the history ‐ of Jesus Christ as a person.


This panel was convened at 10:45 a.m., Thursday, March 26, by its moderator, Douglas Guilfoyle of University College London, who introduced the panelists: Alfred Rubin of the Fletcher School, Tufts University; Malvina Halberstam of Cardozo School of Law, Yeshiva University; Ashley Roach, formerly with the U.S. Department of State; Katharine Shepherd of the U.K. Foreign and Commonwealth Office; and Robert Beckman of the National University of Singapore. INTRODUCTORY REMARKS BY DOUGLAS GUILFOYLE * Welcome to today's panel, "Piracy off Somalia: the Challenges for International Law." I am delighted to introduce a panel bringing together expertise from both academia and government practice. Today's format is a round-table discussion. I will make some brief introductory remarks to frame our discussion before putting specific questions to our panelists. Our panelists today are: * Alfred Rubin, Distinguished Professor Emeritus of International Law, The Fletcher School, Tufts University, and author of the definitive text, The Law of Piracy; * Malvina Halberstam, Professor at Cardozo Law School, Yeshiva University, who headed the U.S. delegation in the negotiations on the Convention for the Suppression of Unlawful Acts Against the Safety of Maritime Navigation, adopted in Rome in 1988 ("SUA Convention"); * Robert C. Beckman, Associate Professor and Director of the Centre for International Law at the National University of Singapore, a prolific writer on law of the sea ("LOS") issues, including maritime security and piracy; We are also very fortunate to have with us two highly informed serving and former government practitioners who have been deeply involved in these issues at the front lines: * J. Ashley Roach, recently retired from the U.S. State Department, and previously of the U.S. Navy JAGC, also a widely published author on LOS issues; and * Katharine Shepherd of the U.K. Foreign Office, a law of the sea specialist who has recently spent a lot of time in Africa working on these issues. We are all familiar with the headlines concerning pirate attacks in the Gulf of Aden and off Somalia's east coast, particularly following the spectacular hijacking 500 nautical miles (rim) off the coast of Kenya of the Sirius Star in November 2009. Even following the organization of the Internationally Recognized Transit Corridor, administered since 1 February 2009 by the European Union Naval Force and patrolled by the naval assets of seventeen countries, attacks have continued. On some industry estimates, the ratio of successful hijackings per attack have dropped from one in four to one in seven following the implementation of the Corridor. (1) The most recent reported hijacking occurred on Thursday last week and over forty attempted hijackings off Somalia have been reported so far this year. The 1982 UN Law of the Sea Convention ("UNCLOS") defines piracy as: (2) (1) an act of violence, detention or depredation; (2) committed for private ends; (3) on the high seas or in a place outside the jurisdiction of any State; and (4) committed by the crew or passengers of a private craft, against another vessel or persons or property aboard. In such cases, the warship of any state has powers to board and inspect suspected pirate vessels and UNCLOS further provides that "every State may seize a pirate ship . . . and arrest the persons and seize the property on board. The courts of the State which carried out the seizure may decide upon the penalties to be imposed...." (3) Customary international law also permits any state subsequently finding a pirate within its territory to prosecute him or her as an exercise of universal jurisdiction. These general rules are expressly incorporated into the chain of Security Council resolutions and regional non-binding agreements aimed at Somali piracy. UN Security Council Resolutions 1816, 1838, 1846, and 1851 are--despite granting the talismanic authority of Chapter VII to use "all necessary means" to combat piracy--at first glance seemingly superfluous and peculiar. …


In this paper we present the Double Weighted Inverse Weibull DWIW, taking one type of weighted function, , and using the Inverse Weibull distribution as original distribution, then we derive the pdf, cdf with some other useful staistical properties.


Fifth Plenary Session of the Seventeenth and central economic work conference clear the low carbon economic development strategy.China's financial industry is surrounding social responsibility and the equator principle as the main line,The organization construction,the customer structure and the business model need to reform and the layout.This article from the responsibility of management system,the construction of the equator principle guiding principles,and Unifies Our country Financial industry Company to govern the mechanism the present situation,discusses the financial institution in the governance mechanism and business development,it is necessary to implement low carbon development idea,the enterprise market responsibility must be and environment,social responsibilities associated,establish adapt to climate change " Three committees and a management " management system,can promote China's financial industry transition and development.


Exaimnination of ultrathin sections of "undisturbed" marin1e sediments from the Gulf of Mexico indicates that they are chlaracterized by a loose, open, random arrangement of particles. The microstructures do not appear to conform entirely to either cardhouse or honeycomb structures.


1. Differential elongation of seedling roots of Artemisia absinthium in response to applied growth substances was used as the basis of a method for assay of growth substances. The use of only 0.1-ml. agar squares for testing the growth of ten roots and marked sensitivity of the roots render the method applicable for small quantities of growth substances. 2. The elongation of roots treated with four substances-3-indoleacetic acid (IAAcid), 1-naphthaleneacetic acid (NAAcid), 3-indole acetaldehyde (IAAld), and 1-naphthalene acetaldehyde (NAAld)-was expressed as a percentage of the elongation of untreated roots. 3. All four substances showed an inhibitory effect on root elongation over a certain range of concentrations (figs. 1, 2). In general, the aldehydes were one-tenth as effective in inhibiting root elongation as their corresponding acids. 1-Naphthalene acetaldehyde was one-tenth as effective as 3-indole acetaldehyde. 1-Naphthaleneacetic acid was less effective than 3-indoleacetic acid at highly inhibitory concentrations, more effective at slightly inhibitory concentrations. 4. For all four compounds, given concentrations were more inhibitory at 4 than at 24 hours. In no instance did elongation of treated roots exceed that of those untreated at the end of a 4-hour period of treatment. A 14% stimulation of root elongation after 24 hours of treatment with 3-indoleacetic acid at a concentration of 10-1 μgm/l and a 10% stimulation with 3-indole acetaldehyde at 10-3.2 μgm/l were statistically established. 5. Juice obtained from Artemisia roots had the capacity to convert 1-naphthalene acetaldehyde to 1-naphthaleneacetic acid. Concurrent with the conversion, however, some of the aldehyde was otherwise changed. 1-Naphthaleneacetic acid was stable in root juice. If the aldehyde has to be converted to acid in order to become active, the conversion must occur within 4 hours in the living root, since the inhibition of elongation observed with the aldehyde showed no increase from 4 to 24 hours. 6. All four substances at relatively high concentrations caused formative effects on roots. Root elongation was virtually stopped, subterminal swellings appeared, and root-hair production was greatly limited. At lesser concentrations, root growth was still strongly inhibited, and a thick fuzz of root hairs was observed, probably an effect caused by the occurrence of more epidermal cells, and therefore more root hairs, per unit root length.


Occurrence and damages of Danothrips trifasciatus (Thysanoptera: Thripidae) on Calophyllum brasiliense (Clusiaceae) in Brazil. Danothrips trifasciatus Sakimura, 1975 (Thysanoptera, Thripidae) is recorded for the first time in Brazil, in the municipality of Garca, Sao Paulo state. Individuals were collected in April 2011 damaging young leaves of guanandi, Calophyllum brasiliense Cambess. (Clusiaceae), forest species of increasing importance in Brazil. Future studies involving aspects on biology and population dynamics of the thrips in this plant species need to be carried out, in order to establish its potential economic importance to guanandi.


Organisations always want to cut cost and maximize profits and share handsome return to its various stake holders. Apart from affordability, the organizations look for cutting down store space which eventually reduces the overheads. Innovations are necessary to ride the inevitable tide of change. Most of enterprises are striving to reduce their computing cost through the means of virtualization. This demand of reducing the computing cost has led to the innovation of Cloud Computing. Cloud Computing offers better computing through improved utilization and reduced administration and infrastructure costs. Cloud Computing is the sum of Software as a Service (SaaS) and Utility Computing. Cloud Computing is still at its infant stage and a very new technology for the enterprises. Therefore, most of the enterprises are not very confident to adopt it. This research paper tackles this issue for enterprises in terms of cost and security. In this paper I discuss the benefits and drawbacks an enterprise can have while they adopt Cloud Computing in terms of Cost and Security. In the end, concluding that Cloud Computing is better for medium and small sized enterprises as compared to large enterprises in terms of both cost and data security.


Purpose To study the clinical value of electrophysiology of vision in traumatic hyphema. Methods According to visual disturbance degree,53 cases (53 eyes) of traumatic hyphema were divided into group A(V≥0.1) and B (V0.1), their fellow eyes working as control groups. Electroretinogram (F-ERG) and pattern visual evoked potential (P-VEP) were recorded respectively. The changes of the latency and amplitude of F-ERG a b-wave and P-VEP P100 were analyzed statistically. Results Compared with control groups, the amplitudes of ERG a, b-wave of injured eyes gropped ( P 0.005).The amplitude was lower in group B( P 0.05). In group B, the drop degree of a-wave( P = 0.003) was significantly lower than that of b-wave ( P = 0.021). The latency was delayed in group B, but no significant difference was found between group A and B ( P = 0.128) . Compared with the control group, the amplitude of P-VEP P100 dropped and the latency was delayed in group A and B ( P 0.05). Between group A and B, the amplitude( P = 0.023) and latency (P = 0.027) were significantly different. Conclusion Electrophysiology of vision can be used as one of objective methods to estimate the vision function of traumatic hyphema.


Objective To study the effects of fluoride on hepatocyte DNA damage and the effects of selenium and VC on hepatocyte DNA damage caused by fluoride in rats.Methods Four groups of male SD rats were provided with deionized drinking water containing 0, F(150 mg/L NaF), F+Se(150 mg/L NaF + 5 mg/L Na 2SeO 3), F+VC(150 mg/L NaF +1000 mg/L VC) respectiverly for 4 weeks. Single cell gel electrophoresis assay was used to test the DNA damage rate in rat liver cells.Results The DNA damage rate(44.80%) of fluoride exposed group was significantly higher than that of the control group(9.40%), the F+Se group(12.60%) as well as the F+VC group(14.60%). The DNA damage rate of the latter two groups were not significantly defferent from the control group.Conclusions The data indicated that high dose fluoride could induce hepatocyte DNA damage in rats, and the properly selenium and VC could antagonize the DNA damage caused by fluoride.


Nine boro rice genotypes were crossed in diallel mating design to study the inheritance of yield, yield related traits and amylose content over three seasons. Data from 36 F 1 and parents were analysed using Hayman's (1954) graphical approach. Majority of the traits studied revealed importance of over-dominance type of intra allelic interaction over the three seasons. The parents were scattered along the regression line indicating sufficient diversity among them for the traits.


To determine the seroprevalence of Oesophagostomum columbianum antibodies in goats in Kashmnir, a study was conducted in Srinagar and Ganderbal Districts, located in central parts of Kashmir valley. ELISA was standardized and evaluated to detect goat Oesophagostomosis in experimental and clinical cases using somatic whole adult antigen of Oesophagostomum columbianum. Plate ELISA was standardized using 5μg/well antigen concentration with 1:100 and 1:1000 of sera and conjugate dilution. Indirect plate ELISA was able to demonstrate the antibody titer at different weeks post infection in experimental goats. A comparison of plate ELISA on suspected field sera and faecal sample
examination by floatation method revealed that 68 (34.34%) samples were found to be positive using ELISA and twelve by faecal examination. The highest prevalence was found in lower age groups in both the seasons, with the increase in age, the infection level decreased. The prevalence was higher in wet season as compared to dry season. The results were stastically significant (P < 0.05). No sex predisposition was seen. Sensitivity and specificity of ELISA was 80.0%, and 21.42%, respectively. This test is therefore quite sensitive for clinical cases; an early diagnosis, however lacks specificity of faecal examination were 10.81% and 90.0%, respectively.


The purpose of this study was to examine the effects of a commercially available aromatase inhibitor (Novedex XT™, Gaspari Nutrition, Neptune, NJ) on serum steroid hormone levels and clinical safety markers. Seventeen resistance trained men (182 ± 6.8 cm, 91.5 ± 14.4kg, 26 ± 4.7yrs, 17 ± 6%) were assigned an 8‐wk supplementation protocol consisting of the oral ingestion of either 72 g/d of Novedex XT™ or 72 g/d of placebo. Body composition, blood, and urine samples were taken at baseline and after wks 4, 8, and 11. Using ELISA and EIA, serum samples were assayed for various levels of steroid hormones (total and free testosterone, DHT, estradiol, estrione, estrone, SHBG, LH, and FSH, and cortisol). Data were analyzed by 2‐way repeated measures ANOVA. Analyses showed no significant change in clinical safety markers through urine or serum. Significant differences were seen between groups for total testosterone (p = .00), free testosterone (p = .00), DHT (p = .00), and body composition (p = .05). However, no significant difference was seen in estriol (p = .33), estrone (p = .878), or estradiol (p = .08). The results of this study indicated that there was over a 300% increase it total testosterone and a 600% increase in free testosterone, without any associated increases in any of the three estrogen hormones over eight weeks. Therefore, Novedex XT™ appears to significantly elevate endogenous serum testosterone without increasing estrogen, thereby suggesting a plausible role for this nutritional supplement as an effective aromatase inhibitor.


1 Past land use can have long‐term effects on plant species' distributional patterns if alterations in resources and environmental conditions have persistent effects on population demography (environmental change) and/or if plants are intrinsically limited in their colonization ability (historical factors).


This is the autobiography of Anna Michener, who suffered physical and emotional abuse behind closed doors at the hands of her parents and grandmother. She was made the scapegoat for her family's many problems and was institutionalized in mental hospitals more than once. At the age of 16 she found a new family and her own voice and wrote this text as an early step toward recovery. The account is of growing up under unspeakable conditions, not of mature reflection but rather an immediate account of unhealed wounds.


IgG4-related disease (IgG4-RD) is a rare condition characterized by an immune-mediated fibro-inflammation affecting various organs (liver, pancreas, heart, kidney, brain among others) with peculiar histopathologic feature. Few epidemiological data have been published so far, although a dramatic increase in the number of patients diagnosed with IgG4-RD has been recorded in the last years. The clinical manifestations of IgG4-RD involve frequently liver and pancreas. Specifically, a crucial challenge in differential diagnosis is IgG4-related sclerosing cholangitis which is frequently accompanied by pancreatic involvement. Inflammatory alterations of liver parenchyma have also been described, with a new nosology of IgG4-autoimmune hepatitis. Type 1 autoimmune pancreatitis is the pancreatic manifestation of the IgG4-RD. The first-ever epidemiological study to estimate the point prevalence of IgG4-related sclerosing cholangitis has been recently conducted in Japan. Moreover, several demographic studies on IgG4-RD involving liver and pancreas have been published in other countries, although the majority of them are cohort studies and data on incidence/prevalence are lacking. This review aims to update the recent epidemiological and clinical knowledge of IgG4-RD involving liver and pancreas, focusing also on the risk of malignancy.


Achieving sustainable urban development during rapid urbanization is one of the important issues worldwide. Eco⁃ economic regionalization (EER) is a complex regionalization method for dividing urban regions into different eco⁃economic functional zones by considering a wide range of local environmental (water⁃heat condition, biodiversity, vegetation coverage rate, etc.) and socio⁃economic ( gross domestic product ( GDP ), population density, human activity pressure, road network density, etc.) factors. Urban and regional planning based on EER might be beneficial for local environmental protection, as well as sustainable economic growth. Previous studies have investigated the principles, methods, and index system for EER application. However, improving the accuracy and dynamic adaptability of EER is essential in order to ensure its application to small urban regions. In this study, the EER approach was modified by simulating population density in urban areas of Zengcheng District, Guangzhou, and an adaptive regionalization model was developed using remote sensing (RS) and geographical information system (GIS) techniques. Improving the accuracy of raw input data for calculating the indices is important to ensure the accuracy of the EER results. Previously, population density was aggregated on an administrative regional basis, whereas, in this study, we estimated population density grid by grid within the built⁃up area of Zengcheng District by linear modeling of the gray value in each pixel from the Defense Meteorological Satellite Program / Operational Linescan System nighttime light data. According to the linear model, the total number aggregated from all these pixels was equal to the statistical population in each administrative region by assuming that nobody lives outside the built⁃up area. Further, an Adaptive Eco⁃economic Regionalization model (AEER) was developed for Zengcheng District in order to enhance the dynamic adaptability of the EER approach. In our AEER model, the study area was first divided into four


Wind design provisions have changed dramatically since the publication of the 1988 edition of ASCE 7: Minimum Design Loads for Buildings and Other Structures. This paper will compare the history of ASCE 7 wind design provisions from 1988 to 2010, and editions in between. Design examples will be utilized in order to show how changes in wind load provisions have altered the design of buildings in various areas of the United States. Civil and structural engineers should find this paper informative, and gain perspective on the history of ASCE 7.


Alkali metal-based batteries (e.g., lithium batteries) are considered the most effective energy storage candidate for portable electronics, power grids, and electric vehicles due to their considerable energy density, power density, cycle life, safety, and competitive prices. The Ni-rich Co-less ternary LiNi
 x
 Mn
 y
 Co1-x-y
 O2 (NMC) (Ni>80%) is one of the candidate materials due to its high discharge capacity (>200 mAh g-1) and high energy density (>750 Wh kg-1). However, the thermal stability of charged Ni-rich NMCs is inferior, following a general negative correlation between Ni content and stability. Such severer degradation in Ni-rich NMCs might lead to dysfunctionality, thermal runaway, and eventually catastrophic failure and explosion of batteries, raising enormous safety concerns. Therefore, it is critical to understand the thermal behavior of charged Ni-rich NMC cathode from different perspectives in order to conduct material design for better thermal stability.
 After literature survey of typical and widely used probes by this community (e.g., diffraction, spectroscopy, imaging), we found these approaches subject to compromise to some degree in the experimental design, resulting in an inadequate description of the thermal degradation mechanism. Here we offer two novel approaches, neutron total scattering and energy-resolved 3D nano-tomography, to probe the reaction and evolution of the charged NMCs under non-ambient conditions in real-time. Such in situ measurements were only accomplished by deliberate experimental design at beamlines and deep integrations of neutron or synchrotron facilities with battery science. In situ heating neutron scattering captures the transition of crystal structure in reciprocal space (by Rietveld refinements), as well as of the local atomic framework in real space (by pair distribution function analysis). Moreover, machine learning algorithms were applied to the 3D nano-tomography datasets to reveal the detailed microstructural and oxidation state progression inside the charged particles. Thereafter, we discussed the key factors which have previously been overlooked by the community and offer constructive suggestions on particle design for thermally stable cathodes from our unique perspective.
 The work was supported by the National Science Foundation under Grant no. DMR-1832613 (F.L.). The machine-learning assisted tomography analysis was partially supported from NASA under 80NSSC21M0333 and NSF under NSF-2119688 (X.-D.Z)


PURPOSE: Device and method for configuring a folder of an application program in an image display device are provided to easily search a necessary application program by modifying a configuration method of an application program folder according to folder configuration modification even information in the image display device. CONSTITUTION: When a configuration of an idle screen is determined, an image display device confirms a folder configuration method (301,303). The image display device configures an application program folder according to the confirmed folder configuration method (305). When a folder configuration modification even is generated, the image display device confirms a folder configuration method to be modified (307,309). The image display device modifies configuration of the application program according to the confirmed folder configuration method (311). [Reference numerals] (301) Is a waiting screen formed?; (303) Check the folder configuration method; (305) Set folders of the waiting screen based on the folder configuration method; (307) Is an event occurred for changing the folder configuration?; (309) Check the folder configuration to be changed; (311) Change the folder configuration method; (AA) Start; (BB,DD) No; (CC,EE) Yes; (FF) End


In April 2003, the University of Arizona Center for Middle Eastern Studies hosted the fifth multi-language conference, whose goal was to bring together teachers and researchers interested in less commonly taught languages such as Arabic, Hebrew, Persian and Turkish. This year's conference emphasized the importance of connecting practical classroom applications and second language acquisition theory. Organizer Kate Mackay (research social scientist at the Center for Middle Eastern Studies), continued the conference's tradition of creating a forum for the intersection of pedagogical theory and practice. Presenters and attendees came from Brigham Young University; Northern Arizona University at Yuma; Princeton University; University of Arizona, Tucson; University of California, Berkeley; University of California, Los Angeles; University of California, Santa Barbara; University of Texas at Austin; University of Utah; University of Washington; and University of Wisconsin, Madison. The following is a summary of featured presentations.


The completion of the Human Genome Project and the International HapMap Project, coupled with rapid advancement of high-throughput biotechnologies including next- generation sequencingNGS� , has facilitated the discovery of genetic and genomic variants linked to many human diseases. Massive amounts of data from genetic and genomic studies provide a great opportunity for researchers to investigate and propose novel statistical methods and algorithms that can effectively identify disease-associated or causal genetic/genomic markers while avoiding an abundance of false positive results. Despite many recent advances in statistical designs and methods for the analysis of genetic and genomic data on complex diseases, numerous challenges remain. For example, complex diseases including many cancers are heterogeneous in both disease phenotypes and disease etiology. The specification of disease phenotype and measurement of risk factors or environmental exposures are often subject to missing data, measurement errors, or over- simplification. Disease susceptibility is often affected by heterogeneous genetic or genomic factors including rare variants and further altered by various environmental exposures. Therefore, novel study designs and analysis methods are essential for proper adjustment of latent heterogeneity, and for robust inferences using data with possible misspecification of disease phenotypes, incompletely measured exposures, or other complexities. This special issue is devoted to original research articles as well as overview papers that propose and discuss innovative study designs, novel probabilistic and statistical models, and analysis methods and/or algorithms for genetic and genomic studies of complex diseases. In particular, genome-wide association studiesGWASprovide an important screening approach to identify single nucleotide polymorphismsSNPsand pathways that


Our aim in the present article is to introduce and study the relation between the deformation retract of the Reissner-Nordstrom spacetime N4 and the deformation retract of the tangent space Tp (N4). Also, this relation discussed after and before the isometric and topological folding of N4 into itself. New types of conditional folding are presented. Some commutative diagrams are obtained.


Two experiments are reported which demonstrate the means to stabilize the photoluminescence from an electrochemically etched (100) Si surface (porous silicon). The strong stabilizing influence of small quantities of water on a nonaqueous [2 mol/l HF in methylcyanide (MeCN)] etching process and the stabilizing effect of hydrochloric acid on a porous silicon surface photoluminescing in solution are described. Mechanisms consistent with these observations are considered as they are commensurate with a silicon oxyhydride emitting species.


Predicted transmitting abilities for somatic cell counts (SCC) are available in the United Kingdom and there is a direct economic benefit attached to reducing SCC as the milk payment schemes include a penalty for high SCC levels in bulk tank samples and sometimes a premium for low SCC. The aim of the present study was to establish the economic importance of bulls' breeding values for SCC in relation to this payment scheme for SCC. To do this, an empirical method was developed using 645071 individual cow SCC and milk yield test-day records from 358 herds. The economic value was calculated by (i) decreasing all individual cow records by 0·01 and comparing the average penalty with the current average penalty, and (ii) taking the derivative of a Gompertz function describing the within-herd penalty per cow as a function of the average within-herd 3-month rolling geometric mean SCC. Mean milk test-day yield and average test-day SCC were 20·4 kg and 262 kcount per ml respectively with, on average, 83 cows tested each day. In the current situation the average penalty paid was 0·54, 0·18 and 3·2 pence per litre depending on whether an England and Wales, Scottish or future payment scheme was used, respectively. Across the population, the economic values per 0·01 decrease in SCC were £1·04, £0·54 and £6·03 per cow per year for these three payments schemes respectively. However these economic values depend strongly on the mean SCC. Herds have different means and as the future population mean is difficult to predict, it is suggested that for herds with the majority of their bulk tank samples in penalty bands 1, 2 or 3+ (average SCC of


Abstract: Radiotherapy plays a critical role in the nodal management of patients with head and neck cancer. The indications, dose fractionation schedules, and results of postoperative radiation therapy (PORT) and elec-tive nodal management (ENI) in various head and neck cancers are reviewed and summarized with common themes identified. Keywords: Elective irradiation, head and neck cancer, lymph nodes, postoperative irradiation, skin cancer. INTRODUCTION Cancers in the head and neck region commonly spread to regional cervical, retropharyngeal and parotid lymph nodes in a predictable pattern. Man-agement of nodal disease is dependent on primary tumor histology and location, extent of primary and nodal disease, surgical resectability of nodal disease and medical operability of the patient. In patients treated with upfront surgical resection of nodal disease, PORT is commonly utilized to re-duce the risk of regional recurrence. Elective nodal irradiation of draining nodal stations has been shown to reduce regional recurrence as well. For example, in mucosal squamous cell carcinomas of the head and neck large prospective, randomized trials have been conducted to define the role for postoperative nodal irradiation and chemotherapy [1,2] and data has existed supporting ENI for at least forty years [3]. The National Comprehensive Cancer Network (NCCN) provides updated con-sensus guidelines for PORT and ENI for common cancers of the head and neck region and these guidelines are a valuable resource for clinicians that provide a national standard for radiation treatment [4-7].


This study explored the relationship between mathematics performance and learning styles among Grade 8 students in the Philippines. The study used a descriptive correlation research design to achieve its objectives, which included determining the profile of Grade 8 students, identifying their learning styles, and examining the relationship between mathematics performance and age, gender, and learning styles. The data was collected through an adapted questionnaire from David Kolb's learning style inventory. The findings revealed no significant relationship between learning styles and academic performance in mathematics. However, it is worth noting that the lack of a significant relationship does not necessarily mean that there is no relationship at all. Motivation, teacher quality, and cultural background may also influence mathematics performance. The findings suggest that educators should consider students' different learning styles when developing effective teaching strategies to enhance mathematics performance among Grade 8 students. This study contributes to the literature on mathematics education and has practical implications for educators seeking to enhance their students' mathematics performance.


The demand for leaf wrapped tempe in Sub District Loa Kulu is influenced by several factors such as income, taste, number family member, expectation future and tempe price. The purposes of this research were to identify and analyze factors influencing the demand of household industry and to know the amount of elasticity of demand of leaf wrapped tempe in Sub District Loa Kulu, District Kutai Kartanegara.This research was conducted from Maret  to April  2017, at Sub District Loa Kulu.The subjects of this research were the exsisting market in Loa Kulu and that sale tempe leaf wrapped.             The data was taken used questionnaires and interviews. Samples taken as many 44 people from 51,453 population.Respondents were taken purposively, who had bought leaf wrapped. Factors demand in the analysis with calculation tool SPSS and the magnitude of elasticity is calculated using manual formula. The result of this showed that income, number family member had significant effect on I± = 0.05. While the taste factor, expectation future and price tempe has no significantly effect on I± = 0.05. against the demand for leaf wrapped tempe. value of 32.2% means the demand variable tempe leaf wrapped can be explained by income, taste, number family member, expectation future and tempe price, the rest is explained by other factors of 67.8%. And the magnitude of elasticity coefficient on demand of leaf wrapped tempe was 0.08. Demand for leaf wrapped tempe in Sub District Loa Kulu is influenced by several factors such as income, number family member. Magnitude the coefficien of elasticity of demand for leaf wrapped tempe is inelastic category.   Keywords: Demand, Leaf Wrapped Tempe, Sub District Loa Kulu


Background Being victimised by bullying is strongly associated with having an underlying chronic condition. The aim of this study was to determine whether primary and/or secondary healthcare utilisation (HCU) is increased in children who are bullied independent of having an underlying chronic illness or disability. Methods Cross-sectional survey of the first wave of the childhood (9-year-old) cohort of the Irish National Longitudinal Study of Children, encompassing 8,568 9-year-olds and their primary carers. Bully victimisation was assessed by a self-reported questionnaire completed by the child at home. The principal HCU outcomes obtained by interview-administered questionnaire with the primary caregiver at home were: visits to general practitioner (GP), Mental Health Practitioner (MHP) and nights spent in hospital in the previous 12 months. Results In logistic regression models, being victimised by bullying independently increased GP visits (OR = 1.13, 95% CI: 1.03–1.25, p = 0.02); MHP visits (OR = 1.31, 95% CI: 1.05–1.63, p = 0.02), though not nights in hospital (OR = 1.07 95% CI: 0.97–1.18, p = 0.18), irrespective of presence of chronic illness or disability. Gender stratified Poisson models demonstrated that victimised girls made increased GP visits (RR = 1.14, 95% CI: 1.06–1.23, p < 0.001) and spent nights in hospital (RR = 1.10, 95% CI: 1.04–1.15, p < 0.001); whereas victimised boys were more likely to contact MHPs (OR = 1.21, 95% CI: 1.02–1.44, p = 0.03). Conclusion 9-year-olds who are victims of bullying are more likely to utilise healthcare services. Different types of HCU patterns were observed by gender. Our study suggests health professionals need to be vigilant that medically unexplained symptoms and behavioural problems in children may be manifestations of bully victimisation, which may present differently in boys and girls. This has important implications for early detection of bullying and appropriate management of victimised children.


In the historical context of promoting our national cultural soft power,this paper discusses the cultivation of translation majors from the essence of sinological edification.Translation means not only interlingual communication and intercultural transplantation but also intralingual interpretation.To fulfill the grand mission of exchanging cultures,a translator should first of all have good command of interpreting tradition inherited from his/her own culture.Sinological edification means subtle absorption,preservation and creation of the superiority of the tradition as well as authority.The status of edification could present the essence of educational experience and produce all-round translators.


This project includes the implementation of ISO 9001:2008 to a private security company, named SEFIEM. Ltd. Co. The company's goal is to improve the performance of all business processes enabling directors manage it through the application of indicators. Through this project seeks showing how beneficial is the implementation of these standards within companies and how it helps an organization to grow due to continuous improvement in its processes. Standards create a good corporation image, the fidelity by customers and also the economic benefits. All these benefits will be reflected in a study based on current and potential market in order to obtain more precise information of the market and also in the financial study conducted by the team.


Rationale: Gaucher disease (GD) is a rare genetic lysosomal storage disorder inherited in an autosomal recessive pattern. GD is due to the deficiency of a lysosomal enzyme, acid beta-glucosidase (or glucocerebrosidase). Type 1 Gaucher disease (GD1) is characterized by thrombocytopenia, anemia, an enlarged spleen, and liver as well as bone complications (Erlenmeyer flask deformity, osteoporosis, lytic lesions, pathological and vertebral fractures, bone infarcts, and avascular necrosis leading to degenerative arthropathy). The diagnosis is usually made in first decades but is sometimes delayed. Parkinson disease, neoplasia, and immune system abnormalities may be associated with GD1. Patient concerns: A patient known for hepatosplenomegaly with hyperferritinemia, anemia, and thrombocytopenia was admitted for Lewy body dementia and bullous pemphigoid. Diagnoses: Type 1 Gaucher disease. Intervention: No specific treatment started. Outcomes: patient died ten months later due to pneumonia. Lessons: To the best of our knowledge, this is the first case of the association between GD1, bullous pemphigoid, and Lewy body dementia. We discuss the central role of alpha-synuclein in these pathologies.


Abstract:This article explores the ambivalent ways that care providers in a southern French hospital (the Center) thought about patient subjectivities and the power and role of language as they argued about how to orchestrate a "good" death in palliative care. By analyzing the case of Monsieur Rami, a 67-year-old Moroccan-born immigrant who died of metastatic cancer in the summer of 2017, I argue against the presumption that individual autonomy, rational choice, and linguistic transparency are hegemonic in Western Europe, particularly in biomedical domains. Instead, I use the disagreements and frustrations that surrounded Monsieur Rami's last weeks to trace out the variety of conflicting ways that care providers talked about his family entanglements, the role of cognitive knowledge and "choice" in end-of-life care, and the power of language itself. Care providers in the Center certainly sometimes characterized Monsieur Rami as a (potentially) autonomous, choosing individual who required transparent communication about his prognosis and diagnosis. But such characterizations served as ideological weapons in battles care providers were fighting amongst themselves over their own contradictory ethical commitments. And in palliative care, those competing ethical commitments were often grounded in assumptions about intersubjectivity and irrationality, as well as the performative power of words.


Urban construction land increase or decrease hooking was an effective way of improving construction land use efficiency and reducing land use pressure of the urban government.However,problems came out in the course of policy implementation such as regional gap,urban extensive land use,difficult conditions for rural traditional production and life style,decrease of farmland quality and villagers' benefit.The reason for these problems was that the government fully dominated the policy implementation course and farmers had no right of speaking.Therefore,the hook policy should be made on the base of keeping government neutral.