Digitization and automation have engulfed every scope and sphere of life. Internet of Things (IoT) has been the main enabler of the revolution. There still exist challenges in IoT that need to be addressed such as the limited address space for the increasing number of devices when using IPv4 and IPv6 as well as key security issues such as vulnerable access control mechanisms. Blockchain is a distributed ledger technology that has immense benefits such as enhanced security and traceability. Thus, blockchain can serve as a good foundation for applications based on transaction and interactions. IoT implementations and applications are by definition distributed. This means blockchain can help to solve most of the security vulnerabilities and traceability concerns of IoTs by using blockchain as a ledger that can keep track of how devices interact, in which state they are and how they transact with other IoT devices. IoT applications have been mainly implemented with technologies such as cloud and fog computing, and AI to help address some of its key challenges. The key implementation challenges and technical choices to consider in making a successful blockchain IoT (BIoT) project are clearly outlined in this paper. The security and privacy aspect of BIoT applications are also analyzed, and several relevant solutions to improve the scalability and throughput of such applications are proposed. The paper also reviews integration schemes and monitoring frameworks for BIoT applications. A hybrid blockchain IoT integration architecture that makes use of containerization is proposed.


The rising profile of poverty in Nigeria is assuming an alarming dimension. It is amazing to note that various poverty alleviation programs has been launched by the government, but the impact of such initiatives leaves much to be desired. The paper highlights on the concepts of Technical Vocational Education (TVE), poverty and the level of poverty in Nigeria. Various poverty alleviation initiative programs and best practices of TVE in the world were discussed. Conclusions were drawn and recommendations made amongst which are: that the government should provide power and other infrastructural facilities so as to encourage the growth and development of small and medium scale enterprises who more often than not are the employer of graduates of TVE institutions thereby creating jobs and reducing poverty in the society and the graduates of the programs should be encouraged to be self-employed by assisting them with soft loans and/or micro credit, in order to achieve the expected outcome of employment creation and poverty eradication in Nigeria.


In this letter, a salty water antenna with beam-steering characteristics is proposed. The antenna combines the idea of the electronically steerable parasitic array radiator (ESPAR) antenna and the water antenna to realize a 360° beam steering. The unique features of water antennas, such as transparency, reconfigurability, and liquidity, are fully utilized. Both the computer simulations and measurements are conducted to validate the performance. The proposed design has a frequency range from 334 to 488 MHz (S11 < −10 dB), high radiation efficiency (>60%), 13 different working states, and a maximum gain of 5.8 dB. Compared with existing pattern-reconfigurable liquid antennas, this new antenna has a wider bandwidth, more working states, and better invisible ability. It is, therefore, a promising candidate for a range of very high-frequency or ultrahigh-frequency applications, such as Internet of Things and maritime applications.


Based on the review of the hydropower development in the watershed,the type,source and pollution characteristics of the solid waste are analyzed.The main problems of its solid waste treatment and disposal are pointed out and the management measures are proposed.


A low cost method for reducing the dispersion in the trajectory of an unguided, spinstabilized, sounding rocket is developed and presented. The method is particularly suited to scramjet flight experimentation because the approach increases the likelihood of meeting Mach number and dynamic pressure objectives. The paper discusses the design and model of the scramjet payload, and two-stage launch vehicle, and the nominal trajectory, as well as a Monte Carlo analysis to quantify the likelihood of a successful scramjet test. Using the results of this analysis, a method is presented for reducing the dispersion in freestream conditions during the scramjet test window. The dispersion reduction is accomplished by modifying the time delay between the burnout of the first stage booster and the ignition of the second stage based on the vehicle state measured during the interstage coast. This method increases the likelihood of a successful test from 71% to 99% without adversely affecting range safety. Since the design and implementation of a vehicle guided control system is not required, this method is relatively inexpensive, making its use highly desirable for low cost scramjet flight experimentation.


The demonstrative multi-media CAI courseware is frequently used and seen in nowadays teaching practice. But some problems such as design at random, overload of information and unnecessary use of it still exist and cause bad effect on teaching practice. This article puts forward some useful opinions through analysis of principles of the application and design of demonstrative multi-media CAI courseware.


A review on the role of physical exercise and sports in the rehabilitation and general management of HIV seropositive individuals and AIDS sufferers is presented. Studies have proven that a carefully directed physical exercise can increase neuromuscular strength and cardiorespiratory fitness. It can also improve the cellular immune system as well as the psychological situations in HIV-infected patients. Furthermore aerobic exercise training results in potentially beneficial increase in both cellular and humoral immunity. However strenuous physical activity leads to immunosuppression; hence aggravating AIDS manifestations. It is encouraged that asymptomatic HIV positive individuals and AIDS patients perform well-prescribed exercises. Strenuous physical exercises and sports competition should; however be avoided as these would result to complications in their health. Physical education and sports specialists should lead in designing and supervising such exercise programs.


Clusters of He atoms formed in a supersonic free jet expansion have been studied by electron-bombardment ionization and mass spectrometry. Distinct magic-number enhancements of ion intensity are observed for clusters of 7, 10, 14, and 30 atoms for both helium isotopes, and for 23 atoms of $^{4}\mathrm{He}$. Dramatic differences in the onset of cluster formation between the two isotopes may be related to the stability of $^{4}\mathrm{He}$ dimers.


Radiation dose on patient has become a major concern today for Computed Tomography (CT) imaging in clinical practice. Various hardware and algorithm solutions have been designed to reduce dose. Among them, iterative reconstruction (IR) has been widely expected to be an effective dose reduction approach for CT. However, there is no clear understanding on the exact amount of dose saving an IR approach can offer for various clinical applications. We know that quantitative image quality assessment should be task-based. This work applied mathematical model observers to study detectability performance of CT scan data reconstructed using an advanced IR approach as well as the conventional filtered back-projection (FBP) approach. The purpose of this work is to establish a practical and robust approach for CT IR detectability image quality evaluation and to assess the dose saving capability of the IR method under study. Low contrast (LC) objects imbedded in head size and body size phantoms were imaged multiple times with different dose levels. Independent signal present and absent pairs were generated for model observer study training and testing. Receiver Operating Characteristic (ROC) curves for location known exact and location ROC (LROC) curves for location unknown as well as their corresponding the area under the curve (AUC) values were calculated. Results showed approximately 3 times dose reduction has been achieved using the IR method under study.


The Author presents how to realize IlasⅡ Integrated Library Automation System Automatic Backup by using cron of Sco UNIX 5.06 and Serv U and Script file written by myself.It fits for middle-little library lack of outlay to adopt.


The UN Sustainable Development Goals establish the need for the development of micro, small and medium-sized enterprises. In world practice, it has been proven that there is a direct relationship between the digitalization of a business and its profitability. According to the McKinsey Global Institute, data-driven business models significantly increase productivity in digitalized industries. Unfortunately, in terms of business digitalization, the Russian Federation and other EAEU countries still lag behind technologically leading countries. To move more dynamically along the path of digital transformation, entrepreneurs need institutional support. This conclusion was drawn based on the results of the research "Institutional regulation of the digital transformation of small and medium-sized businesses" under an internal grant at the Siberian Institute of Management, a branch of the RANEPA under the President of the Russian Federation in 2022. The study uses a multidisciplinary approach. A survey was conducted among representatives of small businesses in the Novosibirsk Region, the Chelyabinsk Region and the Republic of Kabardino-Balkaria. Expert interviews were received from heads of business associations, representatives of the scientific community, and government authorities. On the basis of Russian and foreign best practices of institutional support for digital transformation, the program "Accelerator of Digital Transformation of Small Business" was proposed, which should be implemented at the level of regions and municipalities. The introduction of the developed recommendations into the practice of institutional regulation in the EAEU countries will contribute to the digital transformation of small businesses. Ultimately, this will improve countries' entrepreneurial ecosystems.


Methods: The aim of our study was to investigate the effect of Lactobacillus plantarum BiocenolTM LP96 and Lactobacillus fermentum -BiocenolTM LF99 in combination with flaxseed as a source of n-3 PUFAs on fatty acid profile and enzymatic activity of conventional piglets in problem breed. The experiment was carried out on 36 piglets at the age of 28 days of Slovak white×Landrace cross-breed divided into control (C) and experimental (E) group. The experimental piglets in group E were supplied probiotic cheeses at a dose of 4 g/animal/day for each cheese and in the same period the feed of group E was supplemented with whole crushed flax-seed. Piglets in group C were supplied control cheese at a dose of 8 g/animal/day. Plasma fatty acids were determined using GC-FID. Results were elevated by Tukey test and Anova one way.


The present invention provides a design of a fast switchover Industrial Ethernet ring network redundancy implementation. Forming multiple switches in the ring network, in which network a predetermined master station, a plurality of slaves, a network in a normal state, the master device periodically transmitting packets TEST, and detection packet, the entire network topology maintenance form a logical breakpoint in the master station. When a node on the network interruption, the state of the ring port of the node adjacent to the break are detected and forwarded to the master and the other nodes on the network device main battle open ports originally blocked, all on the network nodes simultaneously refresh the MAC address table, changes the routing data in the network, and reached a steady state, this process is completed within 100ms.


We present a Markov Chain Monte Carlo (MCMC)-based parameter estimation package, CosmoReionMC, to jointly constrain cosmological parameters of the Lambda cold dark matter (ΛCDM) model and the astrophysical parameters related to hydrogen reionization. The package is based on a previously developed physically motivated semi-analytical model for reionization, a similar semi-analytical model for computing the global 21 cm signal during the cosmic dawn and using an appropriately modified version of the publicly available camb for computing the CMB anisotropies. These calculations are then coupled to an MCMC ensemble sampler emcee to compute the posterior distributions of the model parameter. The model has 12 free parameters in total: five cosmological and seven related to the stellar populations. We constrain the parameters by matching the theoretical predictions with CMB data from Planck, observations related to the quasar absorption spectra, and, for the first time, the global 21 cm signal from EDGES. We find that incorporating the quasar spectra data in the analysis tightens the bounds on the electron scattering optical depth τ and consequently the normalization As of the primordial matter power spectrum (or equivalently σ8). Furthermore, when we include the EDGES data in the analysis, we find that an early population of metal-free stars with efficient radio emission is necessary to match the absorption amplitude. The CosmoReionMC package should have interesting future applications, e.g. probing non-standard extensions to the ΛCDM model.


The publication of an epidemiological analysis in British physicians 1954 taught us that smoking is the main cause of lung cancer.1 It was a long way to get this message really in the public and to reduce smoking behavior. Now-a-days in many parts of the world, including the United States, programs for preventing the beginning of smoking, as well as for the cessation of smoking, have been established. These programs lead to increased awareness to the fact that about 10–15% of lung cancer cases (e.g. in the U.S.) arise in life-long never-smokers.2 That means approximately 17,000–26,000 never-smokers in the U.S. develop lung cancer annually.3 If we are looking at death rates, then in both smoking and never-smoking men and women, the death rates of lung cancer are increasing similarly with age.4 Therefore, the proportion of older and elderly patients is also in lung cancer in never-smokers the most prominent one. Possible etiologies of lung cancer in never-smokers are exposure to environmental tobacco smoke,5 occupational or environmental exposure to other carcinogens (radon, cooking fumes, etc.), infection with human papilloma virus 16/18, and an inherited susceptibility (germline mutations of EGFR, polymorphisms of drug metabolizing enzymes). There seems to be a different biological basis of carcinogenesis: never-smokers have a higher rate of EGFR-mutations in exons 19 and 21.6 On the other side K-ras mutations are rare in tumors of never-smokers and the mutations in p53 differ. This leads to the hypothesis that there seems to be a smokingindependent and a smoking-dependent carcinogenesis. There have been reports that the outcome for never-smokers is better than that of smokers.7,8 The retrospective analysis of Subramanian and colleagues9 of 254 life-long never-smokers in this issue of the Journal confirms the preponderance of women (71.6%) in this kind of lung cancer. The median age of the population in the study is 70 years; the stage distribution is comparable between never-smokers and smokers. Regarding the distribution of various histologies, they also find—as in previous studies—the survival rates in the histological subtypes are 60.8% of adenocarcinoma and 13.6% of bronchioalveolar carcinoma, respectively. However, they do not find a better survival in the group of patients with lung cancer in never-smokers. They matched 221 of these patients for gender, histology, tumor stage, and years of diagnosis with smoking patients at the same institution, then used a second control group and still found no statistically significant difference in survival rates. The 5-year survival rate was 27.2% in never-smokers and 31.3% in smokers, respectively. Overall this study demonstrates that with valid statistical analysis, the survival rate in never-smokers is not statistically different than that of smokers. This is in contrast to earlier findings and reminds us that we need the correct statistical design and hypothesis to get the correct answer. Of course confirmation of this result is desirable, but also important is how to explain this result. In summary, the simple question about the smoking status of lung-cancer patients has helped us to detect the causal relationship between smoking and lung cancer and at the least, stimulates the search for the biology of lung cancer in never-smokers. Cell and


One of the most important aspects of an entity is, without doubt, how to finance it, this being an ongoing concern of managers, particularly seeking the cost reduction of the borrowed capital and the increase of the financial profitability instalment. Accessing irredeemable funds is a reality of the recent years. Increasingly more companies are looking to these funds to achieve some development objectives. A thorough analysis of the financing possibilities (subsidy) is important for any entity, but the choice has to be made based on the recommendation of the domain specialists. No price is too high if it ensures you business continuity.


Introduction The absorption of near infrared light by materials provides information about the chemistry and structure of those materials by probing their molecular vibrations. The infrared spectra of biological macromolecules have distinct absorbances that allow Fourier Transform InfraRed (FTIR) spectroscopy to monitor macromolecular changes. FTIR can be carried out in aqueous solution, organic solvents, thin films, deposits, flow cells and membrane environments using μg quantities. Moreover, protein secondary structure can be determined, individual bonds in an enzyme can be monitored and processed on time scales of μs or a few ns with rapid scanor step scan-based instruments. Lipid polymorph structure and lipid phase transitions can be studied along with the physical states and conformational transitions of nucleic acids. Carbohydrates and glyco-conjugates and the interactions between these molecules and proteins or lipids can also be monitored. Membranes can be studied as model systems, as isolated membranes, in cells or as subcellular fractions. The macromolecular structure and composition of tissue, whole cells and bacteria can be used to follow disease. Until the 1980s, infrared spectroscopy was generally carried out using dispersive instruments and the time taken to record spectra of adequate sensitivity precluded easy investigation of biological systems. With the advent of fast computing, the Fast Fourier Transform, new detectors and the earlier development of the helium/neon laser for calibration, commercial FTIR spectroscopy became available. With a sensitivity some three orders of magnitude greater than dispersive instruments, FTIR rapidly became the instrument of choice. This increased sensitivity led to an upsurge in techniques that were previously marginal. The techniques that arose with particular relevance to biological and biochemical systems include reflectance methods, attenuated total (internal) reflectance (ATR), microscopy, difference spectroscopy, time-resolved spectroscopy and surface-based techniques. For a recent review of the techniques involved and their detailed applications see the Handbook of Vibrational Spectroscopy (1).


The taxonomic identification of Eymnoidiniales is the basis for its physiological ecology and red tide research.Based on water and net phytoplankton samples collected from Chinese offshore investigation by The First Institute of Oceanography,SOA in recent years,the identification of gymnoids and systemic taxonomy work were carried out with the purpose to improve the taxonomic system of gymnoids in China and provide basic information for identification of gymnoids in coasts of China.25species of Gymnodiniales were preliminarily identified,6of them were recorded for the first time in China.These 25species belong to 15genera of 5families according to our research here,descriptions and photos of each species are presented in this paper.


The purpose of this research is to analyze the physical condition of the Petanque athletes in Semarang City. The research method used is survey method. The data analysis technique in this study is descriptive quantitative. The population in this study were petanque athletes in Semarang City, totaling 78 athletes. The sampling technique in this study was purposive sampling. The sample in this study amounted to 10 athletes. The instrument used in this test is the test guidelines and measurements of KONI Semarang City athletes. The results of this study are that the average physical condition of the petanque athletes in Semarang City is in the very poor category and the average physical condition of female athletes in Semarang City is in the unfavorable category. The conclusion in this study is that all the physical conditions of the male and female petanque athletes in Semarang City are in the unfavorable category. Suggestions based on this research are for petanque coaches in Semarang City to immediately create a physical training program for petanque athletes in Semarang City so that they can support athlete performance when competing.


Generating representations as dialogue: knowledge acquisition between perception and conception. Knowledge and experiences shaping the normal course of life and its conscious content come in the shape of representations; they encompass elements oriented at ideas as well as at perceptions. The rigid, inflexible nature of representations may be overcome using phantasy, or fictional (imaginative) representations, guided either by directly perceived objects or by the actualisation of concepts and structures. Such flexible or animated representations are the means by which one can enter into a dialogue, an interlocution, with the world of sense experiences on the one side and the realm of concepts or ideas on the other side. Entering into variations of perspectives, attitudes and points of view by one's own inner activity, these two worlds present themselves as distinct yet as unique and particular; they have their own foundation and disposition respectively. Within this dialogue fruitful encounters happen, not only monologues or illusionary congresses.
Such animated fictional representations enhance and facilitate not only encounters with sensual and conceptual realitities, they are fundamental abilities for knowledge acquisition as well. With this perspective, one can delve deeply into the processes of abstraction and concretion, or concentration, and their relation to the theory of universals. Finally, it has to be taken into account that fictional representation with their ligthfulness and their ability to fire one's imagination also have a dark side with its illusional aspects and its mental mechanisms.


Primary biliary cirrhosis (PBC) is often considered to be a dry gland disease caused by frequent involvement of salivary and lacrimal glands. Although high titers of antimitochondrial autoantibodies (AMA) have long been recognized in PBC, little is known about the presence of mitochondrial autoantigens in mucosal compartments such as saliva. We investIgAted saliva and sera in PBC patients and controls for the presence of AMA and mitochondrial antigens. In PBC saliva, AMA were detected in 45 of 49 (92%), with specificity directed against pyruvate dehydrogenase complex (PDC‐E2) alone in 22 of 49 (45%), against PDC‐E2 and branched‐chain 2‐oxo‐acid dehydrogenase complex E2 (BCOADC‐E2) in 4 of 49 (8%), to PDC‐E2 and 2‐oxoglutarate dehydrogenase complex E2 (OGDC‐E2) in 9 of 49 (18%), and to the 3 antigens together in 10 of 49 (20%). Isotyping of the saliva AMA showed that 80% of the patients had immunoglobulin A (IgA) against PDC‐E2, 18% had IgM‐specific PDC‐E2, and 35% had IgG specific PDC‐E2. Similar to serum and bile anti–PDC‐E2 IgA antibodies, the saliva autoantibodies localized their reactivity to the inner lipoyl domain of PDC‐E2. Furthermore, saliva from patients with PBC but not controls inhibited pyruvate dehydrogenase enzyme activityin vitro. In addition, and of particular interest, we detected a molecule with a molecular weight corresponding to PDC‐E2 (74 kd) in PBC but not control saliva. These findings make several important points: first, there appears to be localized mucosal immunity in the secretory system of PBC; second, AMA are readily detected in PBC saliva; and third, PDC‐E2 may be present in the saliva of PBC.


Based on the consciousness,habits and consumption behavior of college students' physical exercise,this paper analyzes their consumption characteristics,rules and influencing factors,in order to provide the theoretical basis and reference for promoting the college sports development and sports industry.


Negative susceptance is experimentally measured in the low resistance state of TiN/Ti/HfO2/W resistive RAM memories. A meminductive-like behavior appears along with the memristive effects. A detailed study of small-signal parameters measured at 0 V after applying positive and negative voltage pulses is presented. A simple model for the conductive filaments consisting in a resistance in series with an inductance is used. In the equivalent circuit, both elements are in parallel with the geometrical capacitance of the structure. Both resistance and inductance show two clearly differentiate states. Positive voltages switch the device to the ON state, in which the resistance value is low and the inductance value is high. By applying appropriate negative voltages, the device switches to the OFF state, in which resistance value is high and inductance becomes negligible. The negative susceptance could be related to lags between current and electric field due to transport mechanisms occurring in the ON state.


A large seismic experiment CELEBRATION 2000 targeted the deep structure in the Central Europe, between the Phanerozoic and Proterozoic European crustal domains. Detailed system of seismic measurements along 1400 km long profile CEL05 permitted to determine details of the crustal structure of the East European Craton, TESZ including Holy Cross Mnts. and Malopolska block, Carpathians and Pannonian basin. The crustal thickness beneath profile CEL05 is changing from about 43-47 km beneath East European Craton to about 3040 km beneath Palaeozoic Platform and Carpathians, and 24-28 km only beneath Pannonian basin. Depth of the consolidated basement with velocity Vp>6.0 km/s is changing from 1-3 km beneath East European Craton to about 5-8 km beneath Pannonian basin, reaching up to 10-18 km in TESZ and Carpathians. East European Craton has a typical thick, three-layer crystalline crust structure (with velocities 6.1-6.4, 6.5-6.6 and 6.8-6.9 km/s, respectively), while in the Carpathian-Pannonian area thin crust is characterized by relatively low Vp velocities (6.1-6.4 km/s in the upper crust and 6.4-6.6 km/s in the lower crust). The velocity in the uppermost mantle is 8.1-8.25 km/s beneath East European Craton and 7.8-8.0 km/s beneath Carpathian-Pannonian area. These results are discussed with other seismic profiles from the area (EUROBRIDGE, P3, P4, TTZ and others).


Porous organic materials are potentially useful for many applications, including catalytic systems, separation processes, and gas storage. Although these framework-like structures vary greatly, they have one thing in common: their components are connected through covalent bonds. Porous organic salts, on the other hand, are a new class of materials with components held together by ionic bonds, the attractive forces between positive and negatively charged ions. They are challenging to produce because their pores usually collapse; the ionic bonds of previously known organic salts are not strong enough to stabilize a porous structure.


Generating large omics datasets has become routine practice to gain insights into cellular processes, yet deciphering such massive datasets and determining intracellular metabolic states remains challenging. Kinetic models of metabolism play a critical role in integrating omics data, as they provide explicit connections between metabolite concentrations, metabolic fluxes, and enzyme levels. However, the difficulties in determining kinetic parameters that govern cellular physiology hinder the broader adoption of these models by the research community. Here we present RENAISSANCE (REconstruction of dyNAmIc models through Stratified Sampling using Artificial Neural networks and Concepts of Evolution strategies), a generative machine learning framework for efficiently parameterizing large-scale kinetic models with dynamic properties matching experimental observations. Through seamless integration and consolidation of diverse omics data and other relevant information, like extracellular medium composition, physicochemical data, and expertise of domain specialists, we show that the proposed framework accurately characterizes unknown intracellular metabolic states, including metabolic fluxes and metabolite concentrations, in E. coli's metabolic network. Moreover, we show that RENAISSANCE successfully estimates missing kinetic parameters and reconciles them with sparse and noisy experimental data, resulting in a substantial reduction in parameter uncertainty and a notable improvement in the accuracy and reliability of the parameter estimates. The proposed framework will be invaluable for researchers who seek to analyze metabolic variations involving changes in metabolite and enzyme levels and enzyme activity in health and biotechnological studies.


Ordered mesoporous carbon supported molybdenum oxides were synthesized via ultrasound-assisted assembly method. Heattreatment was conducted subsequently to obtain molybdenum composites with various oxidation states. The supercapacitive performance of the composites was significantly improved compared to that of virgin mesoporous carbon matrix. The results have shown that different oxidation states of molybdenum influenced the overall electrochemical property of the material significantly. Particularly, composite sample treated at 350 ◦ C containing α-MoO3 exhibited the highest specific supercapacitance, 667.8 F g −1 in 1m ol L −1 KNO3 electrolyte.


Purpose – The purpose of this paper is to analyse consumer behavior during the purchase of floral products in the Greek region and to reveal the socio‐economic characteristics that affect consumers' considerations concerning the selection of both cut flowers and pot plants.Design/methodology/approach – The study is based on cross‐sectional data collected through a questionnaire survey with personal interviews. Respondents' reasons for purchasing floral products are examined. A principal component analysis with varimax rotation was applied in order to provide a more manageable set of variables relating to purchasing. The socio‐economic factors of these reasons were used for estimating the significant relation that exists between them.Findings – People purchase cut flowers and pot plants as part of quality of life, as a convenient gift to other people, for religious and social occasions. Significant differences were revealed only in terms of gender and education level of the respondents with a proportion of...


. Data in the contemporary world has penetrated into every industry and is increasingly becoming a necessity in enterprises, simultaneously it has also become an important factor of production. Maritime transport is one of the most vital transport systems and maritime big data is attracting increase interest from both the industry and academia. In this paper, we present a case study using hierarchical clustering on a dataset about a vessel's behavior during operations. We have also produced visually appealing graphs and charts to assist the data analysis.


A few years ago, the relations between the climate and trade communities were marked by mutual ignorance at best, and more often by deep hostility. The climate community did not want to be hindered by trade constraints. The trade community was so afraid of the damage that climate policies could do to the multilateral trade regime that it was adamantly opposed to any consideration of such concerns. Mutual destruction looked inevitable. Now things are changing. The trade community is realizing that climate change concerns will be high on the political agenda for a long time to come. The climate community is realizing that climate policies will face fierce opposition from four-fifths of human kind if it costs too much in terms of growth and of trade, its main channel.


Based on generalizing the influential factors of passenger train departure time range, the relationship between the passenger train departure time range and the needful number of passenger train stocks has been deeply analyzed. Then, the quantitative description method of passenger traveling convenience degree is put forward, and the multi-objective programming model is established. Finally, the heuristic solving algorithm is designed. The model considers the requirements on departure time range of passenger train grade and traveling section, so that not only the maximum of passenger traveling convenience can be met, but also the needing


One can only praise the elegant presentation of the development of the human nephron, found in this folio. The result of long-continued winnowing of the subject by Dr. Oliver is apparent in the concise and logical portrayal; this clarity becomes blurred only when extensive German passages are quoted; the author is more of a linguist than many of his readers. The study will be most appreciated by the serious student of "kidneys and nephrons." However, if the author's views are accepted, other texts pertaining to renal embryology, both abbreviated and extensive, will require complete revision. The incredible microdissections are most convincing, and as a consequence, one is forced to discard the time-honored concept of two structures within the kidney growing towards each other and uniting. Appreciation must be expressed to the Commonwealth Fund for its support; otherwise the tome might not have been issued in such a generous form. One


Calcium ions (Ca2+) function as universal second messengers in most if not all eukaryotic cells, including the cells of the immunesystem. Ca2+ signals are required for the proper activation of lymphocytes, such as T-lymphocytes, their proliferation, differentiation and effector functions. In lymphocytes store-operated calcium entry (SOCE) through calcium release activated calcium (CRAC) channels in the plasma membrane is the major mechanism to increase cytosolic Ca2+ concentrations and is essential for the activation of T and B cells as well as induction of their cytokine gene production. How exactly store operated calcium entry operates in T cells has remained unclear. While one model, based on results obtained using a variety of F-actin-modulating drugs, involves the cortical actin cytoskeleton, the function of F-actin in SOCE has remained controversial during the last decade, since independent studies have found no effects of the same drugs on SOCE in other model systems such as the rat basophile leukemia (RBL) cell line. The first part of this thesis aims at defining the role of the actin cytoskeleton during SOCE in human T cells.
The data presented in this thesis clearly demonstrate that the F-actin cytoskeleton in human T cells has no role in SOCE. These results therefore contribute to our understanding of calcium signaling in cells of the immunesystem.

The second part of this thesis focuses on coronin 1, a member of the conserved WD repeat containing protein family which is encoded in mice (and human) by the gene coro1a. Coronin 1, which is specifically expressed in leukocytes, was originally identified as a protein that is maintained around phagosomes containing live mycobacteria, thereby preventing the fusion of the mycobacterial phagosome with lysosomes and mycobacterial destruction.
The aim of this part of the thesis was to define the function of coronin 1 in immune cells by characterizing coronin 1 deficient mice with a special focus on T cell development, T cell receptor signaling, migration and survival as well as the proposed regulatory role of coronin 1 in F-actin dependent processes. We found, in contrast to the long held dogma of coronin 1 being a major regulator of the F-actin cytoskeleton, that coronin 1 regulates cellular signaling rather that F-actin modulation.
Coronin 1 was shown to interact with phospholipase C γ1 (PLC γ1) thereby being an important regulator of inositol-1,4,5-trisphosphate (IP3) generation from phosphatidylinositol-4,5-bisphosphate (PIP2). The absence of coronin 1, although not affecting T cell development, resulted in a profound defect in Ca2+ mobilization, interleukin-2 (IL-2) production, T cell proliferation and T cell survival in naive T-cells.
Finally in the last part of this thesis we provide data showing that coronin 1 maintains the balance between survival and apoptosis in naive T cells independent of F-Actin via a calcium/calcineurin dependent pathway.
The data presented in part two and three of this thesis establish the leukocyte specific protein coronin 1 as an essential regulator of T cell receptor signaling as well as naive T cell homeostasis and survival. This work refutes the proposed role of coronin 1 in the regulation of the F-actin cytoskeleton, instead providing evidence for coronin 1 being a central regulator of Ca2+-dependent signaling in T cells. The work described here further offers new possibilities for the development of compounds for the treatment of T cell mediated disorders of the immunesystem.


The final chapter emphasizes that numismatics may be one of the oldest fields of humanistic inquiry, but it is still evolving in step with other, more modern disciplines. Researchers today want to know more about the non-elites of history, the nameless masses whose lives made possible the celebrated deeds of kings, queens, and emperors. Coins may seem particularly unsuited to this task since they are state-sponsored ego-facts bearing the names, faces, and boasts of the rich and famous. Cognitive numismatics, however, provides a new way of seeing in coins the common people—how they worked, what they thought, when they had a bad day. This approach brings the reader back to meme theory within the busy confines of an ancient mint. It completes the life cycle of a coin by examining its removal from circulation as an economic instrument, perhaps ending its journey as some other artifact of everyday experience.


Abstract In Rosenthal's Centipede Game, if at the start of play it is commonly known that the players will choose rationally at vertices that are actually reached, then the backward induction outcome results; that is, the first player "goes out" at the first move.Journal of Economic LiteratureClassification Numbers: C72, C73, D82.


The oil cells and mucilage cells in the leaves of 13 species in 5 genera (Lauraceae) were comparatively studied with the methods of tissue clearing, paraffin sectioning and semi-thick sectioning. The results are obtained as follows:Oil cells distribute in the leaves of 11 species in 5 genera. Their shape is spherical and diameter is about 30~40μm. Mucilage cells distribute in the leaves of 8 species in 4 genera. The shape of most mucilage cells is ellipsoid and the length of long axis is about 60~100μm. From the observation on clearing leaf,the distributive density of oil cells is different from each other. As for the transverse section of leaf,oil cells distribute in all mesophyll in some species, in the spongy parenchyma between palisade and spongy parenchyma in some species, and only in palisade parenchyma in some other species. Mucilage cells distribute in all mesophyll in some species and only in palisade parenchyma in some other species. Above all,there are some obvious differences among species in distributive density of oil cells, in distribution places of oil cells and mucilage cells and in their sizes. Those structural characteristics are significant for the classification of Lauraceae.


: People have been fascinated with humanoid robots for over two decades. They are expected to assist and collaborate with humans in the future. However, due to the limitations and complications of bipedal humanoids' walking mechanisms, this goal is still a long way off. In this paper, we have presented a walking mechanism algorithm using gait analysis to mimic the human walking pattern and applied that knowledge to enable the 17-DoF bipedal humanoid robot to walk in a constraint environment. The basic sequence of stance and swing phases of human locomotion is studied and used to control servo motors to perform the walking action of the robot. These robots can be useful for social interaction and collaborative tasks in the near future.


PURPOSE
To use Control Point Analysis (Sun Nuclear Corporation, Melbourne, Florida, USA) to analyze and compare delivered VMAT plans for three different treatment planning complexity levels.

METHODS
Nineteen patients were chosen and fully anonymized for the purpose of this study. Ten SBRT, six H&N, one breast and two prostate VMAT plans were generated on Pinnacle3 and delivered on a Varian LINAC. The delivered dose was measured using ArcCHECK™. Each plan was analyzed using SNC Patient 6 and Control Point Analysis. Gamma passing percentage was used to assess the differences between the measured and planned dose distributions and to assess the role of various control point binning scenarios.

RESULTS
The prostate cases reported the highest gamma passing percentages for SNC Patient 6 (99.3%-99.5%,3%/3mm) and Control Point Analysis (99.1--99.3%,3%/3mm). The mean percentage of passing control point sectors for the prostate cases increased from 48.9±3.1% for individual control points to 69.5 ± 3.9% for 5 control points binned together to 100±0% for 10 control points binned together. Over all, there was a trend in the percentage of sectors passing gamma analysis increasing with the increase of the number of control points binned together in one sector for both passing criteria considered (48.9±3.1% for individual control points to 69.5±3.9% for 5 control points binned together in one sector to 100±0% for 10 control points binned together in one sector for the prostate).

CONCLUSION
The delivery accuracy per control point depends on the MU/control point (SBRT) and the plan degree of modulation (H&N).


Foreword Preface Beginnings School The Anglo-Chinese School, Ipoh Boarding School Lessons School Activities Raffles College 1938-1941 Raffles College Teaching Staff College Life War in Europe The Japanese Invasion The Fall of Singapore Homeward Bound Glossary


We provide sufficiently large sets of eigenvalues that determine the potential of a Schrodinger operator on the unit interval [0, 1] partially known on [a, 1] and belonging to W k, p in a neighborhood of a (k ∈ ℕ ∪{0}, p ∈ [1, +∞]). The number of these given eigenvalues depends on (a, k, p).


Karst rocky desertification is a special kind of land desertification developed under violent human impacts on the vulnerable eco-geo-environment of karst ecosystem. The process of karst rocky desertification results in simultaneous and complex variations of many interrelated soil, rock and vegetation biogeophysical parameters, rendering it difficult to develop simple and robust remote sensing mapping and monitoring approaches. In this study, we aimed to use Earth Observing 1 (EO-1) Hyperion hyperspectral data to extract the karst rocky desertification information. A spectral unmixing model based on Monte Carlo approach, was employed to quantify the fractional cover of photosynthetic vegetation (PV), non-photosynthetic vegetation (NPV) and bare substrates. The results showed that SWIR (1.9-2.35μm) portions of the spectrum were significantly different in PV, NPV and bare rock spectral properties. It has limitations in using full optical range or only SWIR (1.9-2.35μm) region of Hyperion to decompose image into PV, NPV and bare substrates covers. However, when use the tied-SWIR, the sub-pixel fractional covers of PV, NPV and bare substrates were accurately estimated. Our study indicates that the "tied-spectrum" method effectively accentuate the spectral characteristics of materials, while the spectral unmixing model based on Monte Carlo approach is a useful tool to automatically extract mixed ground objects in karst ecosystem. Karst rocky desertification information can be accurately extracted with EO-1 Hyperion. Imaging spectroscopy can provide a powerful methodology toward understanding the extent and spatial pattern of land degradation in karst ecosystem.


Although details of its actions remaining completely understood, it is well established that amyloid β-peptide (Aβ) plays a role in the pathology of Alzheimer's disease. As a result of this, Aβ has become the target of a number of lines of research, all aimed at preventing the production or deposition of Aβ or clearing Aβ deposits once they have been formed. One novel approach, anti-Aβ vaccination, evoked considerable interest not only within the scientific world but also in the lay community following observations in animal models of Alzheimer's disease that vaccination could prevent formation of amyloid plaques or even dissolve them. Enthusiasm turned to pessimism, however, when a small number of patients developed inflammation of the brain, apparently as a complication of the vaccination, in phase II trials. Three recent reports may help to resolve the controversy. A hint that the vaccination approach may not be dead comes from two articles recently published in Nature Medicine. McLaurin and others (2002) studied the humoral and cellular immune responses evoked by vaccinating transgenic mice that provide a model for Alzheimer's, with protofibrillar/oligomeric assemblies of Aβ42. They report that therapeutically active immunization, which reduces cerebral Aβ deposits and partially ameliorates cognitive impairment in these mice, can be achieved by induction of immunoglobulin G2B subclass antibodies against residues 4-10 of Aβ. Notably, they observed that these antibodies can inhibit Aβ fibril assembly and toxicity in the absence of activation of microglial or other cellular inflammatory responses. If confirmed and extended to humans, these findings might provide a basis for improved immunization antigens. The authors also note that these results might provide a novel target for treating Alzheimer's disease with small-molecule approaches that could circumvent problems associated with immunotherapy. Hock and others (2002), in an article published in the same issue, used immunohistochemistry to study the brains of transgenic mice and human patients with Aβ pathology to characterize antibodies produced in humans in response to vaccination with Aβ42. Collecting sera from patients with Alzheimer's disease who had received two injections of preaggregated Aβ42, they found that antibodies within immune sera can recognize Aβ plaque and diffuse Aβ deposits, but they do not cross-react with native full-length amyloid precursor protein or its physiological derivatives. They interpret their findings as suggesting that vaccination of Alzheimer's disease patients with Aβ42 may induce antibodies that have a high degree of selectivity for target structures that play a pathogenic role in Alzheimer's disease. A third report by Pfeifer and others (2002) in Science raises questions, however. These authors immunized APP23 mice against human Aβ. Five months later, stereological analysis revealed a significant reduction in cerebral amyloid load compared to controls. The authors noted, however, that immunized mice displayed a twofold increase in the frequency of cerebral hemorrhage. Most of the hemorrhages occurred in areas affected by amyloid angiopathy and could clearly be attributed to amyloid-laden vessels. The authors interpret their findings as suggesting that Aβ immunization can increase the risk of cerebral hemorrhage by weakening of amyloidotic vessel walls, perhaps by antibody binding to vascular amyloid, which triggers an inflammatory reaction. Each of these studies will undoubtedly trigger substantial interest and follow-up by other research groups. It will be interesting to see what further studies of vaccination strategies for Alzheimer's disease teach us.


The construction of pebble bed downdraft gasifier is proposed. The realization of technology advantages such as higher calorific value of gas, higher carbon conversion efficiency and good economic benefit is explained from the influence factor on gasification process.


This article chronicles the treatment of same-sex couples in England and the Republic of Ireland in recent years in order to ascertain (i) the impact that incorporation of the European Convention into the domestic law of each State has had on the rights of same-sex couples, (ii) what the introduction of civil partnership legislation might mean for the future of the same-sex marriage debate, (iii) the position of prospective same-sex adoptive parents in each jurisdiction, and (iv) what the law is proposing for those couples who do not formalise their relationship, whether same-sex or opposite-sex. Through a comparative analysis of the many recent developments that have taken place in each jurisdiction, the article concludes (i) that when interpreted correctly by the national courts the European Convention has been of little benefit to same-sex couples since its incorporation, (ii) that civil partnership may sound the death knell for same-sex marriage, (iii) that the Irish stance on adoption by same-sex couples may be illogical in light of a recent decision handed down in Strasbourg, and (iv) that significant progress has been made as regards those opposite-sex and same-sex couples who do not marry or register their partnership, with a redress scheme for such couples at the legislative stage in the Republic of Ireland.


The rapid increase in technological developments worldwide has provided the impetus for change in engineering training and education. To meet these transformations, it is crucial that engineering education programs generate graduates with technical and professional skills to become easily accustomed to working environment. Educational institutions contribute to this agenda by outlining the attributes that are central in producing graduates with satisfactory levels of knowledge, skills and attitudes. This paper investigates how these knowledge and skills could be acquired through laboratory works and laboratory reports. Laboratory experiments are practical activities used to integrate theory with practice, and are significant in enabling the students to make the connections between theory and practice. Which types of laboratory skills are commonly practised during laboratory sessions in an engineering course? Is the current laboratory assessment valid? This paper will examine these issues further and recommend several measures to enhance the practice of laboratory experiments in Malaysian universities.


In bivariate normal population,  ; i = 1, 2, . . . N, with mean vector and varkov matrix   , , c : variation coefficient. Estimate of m 1 , m 2 , dan r, must be with rekursive linear methods, because equations system is not linear. Significance test carry out with hypothesis 1.     H 01 : r = 0  vs  H 11 : r > 0, or r m 2 , or m 1 < m 2 , or m 1 ¹ m 2 .  (change one, just take with problems) Test statistik is  ~ t (n-2) . s evaluate with formula  , c : joint variation coefficient. If H 01 reject, must be significance test of correlation r, with test statistic X 2 = -2 ln p 1 – 2 ln p 2 ~ c 2 2 . p 1 and p 2 , is probability of X and Y greates than observations under H 02 . In practice, values of p 1 and p 2 , evaluate with distribution t n for fixed signficance coefficient. Keywords: variation coefficient, rekursive linear methods, relative efficient, significance test


16. Abstract In response to petitions by the golf cart industry the National Highway Traffic Safety Administration reviewed its position on low speed vehicles and has taken steps to define a new class of low speed vehicle (LSV) which is exempt from the federal motor vehicle safety standards (FMVSS) that apply to motor vehicles. A new safety standard, FMVSS 100, has been proposed to regulate this new class of vehicle.


Despite being an activity present in the daily life of Brazilians since 1960, dubbing is a subject rarely studied in academic environment. Over a little more than a decade, the period analyzed by this study (2002 to 2014), it was found a small number of academic papers on the subject (theses, dissertations or monographs). Most of the research does not focus on how the translator does the translation for the dubbing, but how the dubbing process occurs. In this context, the present study aims to give a brief overview of these researches, showing the most significant: a little about dubbing in the world, some details about dubbing in Brazil, as well as aspects like the criticisms related to dubbing, dubbing types, among other topics addressed by the research. A comparative table was made from the works found, in order to facilitate the identification of the topics most covered in the researches.


Complex systems are often a derivative of the current trend that dictates increased functionality and performance. Mobile phones that provide internet access and music player, fighter aircraft with fly-by-wire for flight control, and energy grid that also monitors usage and recommends corrective actions are few of the examples of emerging complex systems. There are a large number of causes that could lead to increased complexity of a system, such as (1) increase in number of parts, (2) increase in number of interactions, and (3) integration of multiple technologies. Increase in complexity makes these systems significantly challenging in terms of design and optimization, resulting in large time and resource investment. Therefore, it is typical for complex systems to use non-mature technologies that are expected to mature along the way. However, such infusion introduces significant levels of uncertainty, which historically have led to explosion in development cost. In this paper, we assess the impact of uncertainty on a complex system. Through numerical simulations, we demonstrate that increasing complexity does not necessarily result in vulnerability of a system to uncertainties. These results challenge the conviction held by complex system design community, which assumes complexity and uncertainty have a direct correlation. Our results indicate that selection of system architecture is critical for system robustness. This should provide motivation for further research in the complex system arena.


DENI APRIYANTO. Analysis the Determinants of Jakarta Composite Index (JCI) Return on Indonesia: ARDL Model Approach. Supervised by IMAN SUGEMA. The stock market has a strategic roles in one country's economic improvement in the era of modernization. The stock market rapid development especially in developing set a historical record in the financial sector such as Indonesia. The purpose of this study is to determine Jakarta Composite Index (JCI) stock return development as well as analyze the relationship between economics variables such as oil prices, gold prices, export, import, and exchange rate to stock returns. The data used in this paper are monthly time series data from January 1998 until May 2015 with ARDL method. ARDL method can estimate linear regression model to analyze long-term relationship involving cointegration test between variables time series. Variables the results indicate that gold price significantly and positively whereas import significantly and negatively have impact to stock return on the long-term. Oil price significantly and positively while import and exchange rate significantly and negatively have impact to stock return on the short-term.


A girl with polydactyly has had respiratory tract problems, including atelectasis, since birth. She has a high arched palate, a tongue hamartoma and dysmorphic face. Electron microscopy of nasal and bronchial brush biopsies repeatedly revealed centriole/basal body disarray and extreme sparseness of cilia. At the age of 2 years and 11 months, she displayed retardation of both motor and mental skills.


Based on illustrating building engineering safety production management system,scheme,system and safety assort design facility,the safety production management software and hardware management standard were generalized,the field management planning of four large damages in building engineering safety production were proposed correspondingly so as to reduce loss and decrease human casualty.


To study the influence of the magnetic field on the normal low-pressure glow discharge, an electrode coaxial system with a meshy tubular cathode and an internal anode was used. A current was passed through the anode to obtain the azimuthal magnetic field crossed with electric field. Oscillography of the signals from the electric probe and photodiode, together with video recording, made it possible to establish the movement of the discharge luminous region along the electrodes. When AC current with a frequency of 50 Hz was passed through the anode, the discharge movement was oscillatory – from one end of the system to another.


DEVELOPMENT OF SEDIMENTATION OF THE ZECHSTEIN DEPOSITS IN THE REGION LUBIN LEGNICKI –SIEROSZOWICE The author analyses the Zechstein lithology and the spacious relations of individual lithologic-stratigraphical horizons in the region Lubin Legnicki-Sieroszowice. On this basis have been determined the palaeogeography and the sedimentary conditions of these deposits. The deposits of the Werra (Z1) cyclothem were formed under the conditions of deep shelf. The greatest thickness of carbonates was in the shallow regions, that of sulphates in the·deeper parts of slopes, and that of chlorites in the central portions of the remaining depressions (Fig. 1). The carbonates, the Lower Werra anhydrite and the oldest rock salt have filled up the primary cavings forming here, like as in the other parts of the Fore-Sudetic monocline, the meridionally stretching bays. The Upper Werra anhydrite was already laid down, as a product of new -cycle of chemical sedimentation, in a basin of flat and even bottom.


Previous research has highlighted that, in addition to being operationally opaque, the concept of state capacity has been confined to national and cross-national analysis, with inadequate attention paid to variations at the regional and sub-national levels of the state. Our current research seeks to help remedy this lacuna. Inspired by the growing consensus that state capacity is not monolithic, but instead comprises capabilities distributed in distinct ways across sectors and institutions, we have developed a parsimonious approach to understanding the concept so as to increase its utility. Specifically, we explore variations in the provision of government services across sectors, wealth, geography, and urbanity in three countries: India, Peru, and Ukraine—representing Southeast Asia, Latin America, and Eastern Europe. Importantly, we offer an analysis of state capacity as a function of variation as measured by standard deviation.


Objective To investigate the impact of childbirth on the sexual health of primiparous women in China and the prevalence of womens postpartum sexual problems. Method In this cross-sectional study obstetric records of 460 primiparous women delivering a live-birth at the First Affiliated Hospital of Chongqing University of Medical Sciences between November 1 2000 and July 31 2001 were analyzed together with the data collected from questionnaire survey conducted six months after delivery. Results Totally 460 women participated in the questionnaire survey. Though 94.74% of the subjects had resumed sexual activity within six months after birth most of them had experienced postpartum sexual problems among which dyspareunia was the most common type. There was no significant association between delivery types and womens sexual health status in six months after birth including their satisfactory degree of sexual intercourse sexual desire sex active rate the incidence of dyspareunia and pubococcygeal muscle strength (P>0.05). Only 20.80% of women had knowledge of sexual health and 8.02% of them had consulted for sexual problems. Conclusions Womens postpartum sexual health problems were very common they deserve more attention. There was no significant association between delivery types and womens postpartum sexual problems at the 6th month after delivery. (authors)


Many scientists work on the research of various aspects of the rural tourism functioning, but despite this, in the scientif ic f ield still remains the problem of uncertainty and ambiguous interpretation of the definitions in rural tourism, which is primarily due to the multidimensional nature of this type of activity and the lack of understanding of its essence. Therefore, the objective of this article is to study and generalize the terms and concepts that occur in the conceptual f ield of rural tourism. Different approaches are applied to determining the essence of rural tourism not only in Ukraine but also abroad. The most common of them is the definition of rural tourism as one being implemented within rural areas. But, in our opinion, this approach is controversial and cannot claim to be the most objective, as in the practices of different countries there is diversity not only in the types and forms of rural tourism, but also in relation to the territorial size of rural administrative units, their definition by population etc. And the peculiarity of rural tourism is not only in its implementation in the countryside, but also in the specifics of tourist services that are provided. The article analyzes the definition of the "rural tourism" concept proposed by different authors, specifies the use of the terms "rural tourism" and "rural green tourism" in the scientif ic f ield, describes the foreign approaches to the definition of rural tourism. The relationship between the concepts of "rural tourism", "agro-tourism" and "ecotourism", which is often debatable, is also defined. It can be argued that rural, agroand ecotourism have different contents and imply different goals of activity. But in the field of science there is a commonplace approach to understand rural tourism as a kind of synthesis of three varieties eco-tourism (green), agro-tourism (farmer) and rural tourism. At the same time, the concept of "rural tourism" in its contents is much broader than the concept of "agro-tourism", which acts as one of its most common organizational forms, and to a certain level correlates with the notion of "ecological tourism", although they are not identical. The article proposes a generalization of the essence, specific features and functions of rural tourism, based on modern research in this direction and the assertion that the main service of rural tourism is not just providing tourists with temporary residence in the country farmstead, but provision of a comprehensive service for tourists, as well as taking into account its role as an instrument for ensuring sustainable socio-economic development of rural areas.


Preface I: WHOSE LAND IS IT ANYWAY? A New Town is Born A Mutiny, A Martyr and Some Myths Farmer, Farmer, Give Me Your Land The Murky Tales of Noida Extension Formula 1: Zipping through the Fields II: THE IMPACT OF ACQUISITION Poof! The Cash is Gone. Where's My Gun? The Cost of Building No Home for the Bristled Grassbird III: NEW OWNERS OF AN OLD LAND Isles of Urbania The Creation of an Education Bazaar IV: THE SCHIZOPHRENIA OF THE PERI-URBAN TOWN The Big, Fat Gujjar Wedding Urban Villager Art and the City Greater Noida Heavens V: GROWTH PANGS OF YOUNG TOWNS The Complexities of Adolescence Our Cities, Our Future Annexures Bibliography


In this paper, we present a simple image depth level estimation algorithm. From the dark channel prior theory, an estimate of the air transmittance in the image is calculated. In wild surveillance, the disparity in the image poses a huge challenge for smoke detection and other video analysis tasks. Appropriate depth level estimation provide significant prior knowledge for subsequent identification and detection. For landscape images, we can approximate the air transmittance to depth information for histogram analysis. The depth value is segmented by a multi-threshold segmentation algorithm, and the resulting image can be used for forest fireworks detection and the like. This method does not rely on samples and classifiers, and the algorithm does not require training. The final experimental results show that the depth level estimation of a single landscape image based on the dark channel prior can achieve good results.


The Chinese landscape painting started in the JIn Dynasty and developde to perfection in the Song Dynasty.Its development was a long and fruitful process in the history of Chinese painting.From the feature of ancient Chinese liferati's landscape paintings we understand the history and appreciate the paintings with unique characteristics such as the following:1.embodiment of thoughts and style in painting;2.unification of form and content,and 3.scholarliness in pqinting style and expressive power beyond paining.


This research was initiated from the Pamsimas program targets have not yet been achieved. The causes were limited water sources and raw water supply, sanitation and hygiene behavior, public awareness of the importance of healthy living behavior was low. This study was to describe and analyze the implementation of the Pamsimas program and the supporting/inhibiting factors of the Program. This study used a qualitative approach by selecting key-informants based on a purposive sample technique. The results showed that the the implementation of the Pamsimas Program in Blora Sub-district was not optimal in terms of the variables as a prerequisite for program implementation. These prerequisites tend to be rigid, making it difficult for program implementers in the field to make decisions that are not included in the standard operational procedures (SOP). On the other hand, the individual and community behavior and participatory to the program in supporting the provision of clean water to be positiveBesides that the factors of limited water sources and raw water supply, unsafe sanitation and drinking water remained unsolved. Recommendations of the conclusions of the study are the delegation of authority related to the bureaucratic structure, especially the standard operating procedures (SOP) and the absence / scarcity of raw water sources for clean watethat needs attention to program managers in the field.


ABSTRACT Sequence stratigraphy, which consists largely of old, well-established concepts recently given new validity by the advances made in seismic stratigraphic interpretation, involves grouping strata into genetically and chronostratigraphically constrained units. Peter R. Vail and his co-workers have demonstrated that these units (depositional sequences and systems tracts) comprise predictable depositional and lithologic facies. The Cockfield/Yegua Formations of southwestern Louisiana provide some very clear examples of features predicted by the Vail model. Thick turbidite sands from the downdip facies (the Arco Hoffpauir well, south central Calcasieu Parish, for example) can be assigned to the lowstand slope fan subdivision of Vail's lowstand depositional systems tract. Farther updip, the Cockfield of northernmost Calcasieu Parish and of Beauregard Parish represents the transgressive systems tract. In southern Beauregard Parish the sands are of distinctive open-shelf facies with geometries indicative of transport by retreating storm surge waters. In the central part of the parish, distributary mouth bar sands occur, and in the north log patterns indicate fluvial point bar sands. Above the Cockfield is a distinctive calcareous unit, the Moodys Branch Marl, which has already been identified (by Vail and Baum working with outcrops in Alabama) as a condensed section indicative of maximum sediment starvation corresponding to the approximate time of maximum transgression. It is particularly significant that a feature originally interpreted as a simple unconformity, but increasing in magnitude towards the basin, has been described at this horizon by the present authors. This feature is here reinterpreted to be a consequence of basinward sediment starvation affecting the uppermost zones of the Cockfield beneath the Moodys Branch. The overlying Jackson (Yazoo) shales, above the Moodys Branch, probably represent the downdip portion of the highstand systems tract, although no distinctive downlap patterns have yet been recognized. Sequence stratigraphy is shown to be applicable to the Gulf Coast subsurface and to have important predictive capabilities which represent a significant advance in our understanding of sedimentary basins.


In this paper a tunable multi-wavelength erbium doped fiber laser, based on a Mach–Zehnder interferometer, is presented. The interferometer is achieved by splicing a piece of photonic crystal fiber between two segments of a single-mode fiber. Here, by changing the curvature radius in the Mach–Zehnder interferometer, the single-, double- or triple-line emissions can be tuned from 1526 to 1550 nm. Finally it is shown, via experimental results, that the laser has high stability at room temperature.


The electrical treatment of fibroma which I originated has made great strides despite the railings of charlatans and incompetent persons; it is not necessary to refer to this subject again, because it is a child that will grow of itself, and is amply able to take care of itself. To-day I invite your attention to a subject of equal interest, I mean the treatment by electricity of salpingo-ovaritis, and I sincerely hope that it may have the same useful future, more restricted perhaps, because at present it is restricted to a certain number of cases, but in any case worthy of your consideration. Salpingo-ovaritis is a disease which has long been recognized, but under names which I have changed very often: Phlegmon, pelvic-peri-tonitis, lymphangitis, adeno-lymphangitis, cellulitis, peri-metritis, para-metritis, peri-uterine, phlegmasia, etc.; all of these titles being used to picture a disease originating in the lymphatics, in the cellular tissue, or


This paper presents a steady state approach to prevent voltage collapse in a power system. The power system operation close to stability boundaries is an important factor which may lead to voltage instability conditions. There are different ways to prevent voltage collapse in the power system; one of this is the correct coordination of the protection devices to avoid undesirable equipment disconnections.This paper proposes a new method to coordinate the back-up zone in the distance protection scheme. The methodology uses both Optimal Power Flow (OPF) and Continuation Power Flow (CPF) solutions to determine the impedance seen by the relay. These impedances are later compared to conclude which is the best option to set the parameter for the back-up zone in the relay. The methodology also considers the distance to Maximum Loading Point (MLP) and the corresponding Voltage Collapse Point (VCP). Therefore, undesirable disconnections can be avoided when the power system operates close to the stability boundaries. In order to demonstrate and validate the methodology, simulations are carried out on the IEEE 14-bus test system using MATLAB.


The number of new SNPs has grown rapidly, but most have low enrollment and enrollment growth has been slow, apart from one-time transitions from existing plans in 2005-2006 and early 2007.


With some assumptions and limitations, various methods have been developed in literature mainly for loss allocation in transmission network and afterwards extended for radial distribution network and some methods are specifically developed for radial distribution network. But, these methods are not suitable for microgrids which are integrated with conventional grid at sub-transmission and distribution levels depending on their geographical location. This paper presents a loss allocation method based on power flow results and relative position of buses for interconnected microgrid which is very effective in case of frequent change of generations due to intermittent nature of renewable resources. The implementation of the proposed method is very simple in microgrid with both meshed as well as radial topology without any computational complexity and requires only power flow solution and network data. The results are illustrated for different generating conditions of renewable sources in microgrid to demonstrate the efficiency of proposed loss allocation method.


This document is about malware analysis, with a particular focus on exploit-based Internet worms that spread from one host to another over the network by exploiting a software vulnerability in the new host being attacked. Based on our experiences analyzing real worms that use this method of worm propagation we develop a model that divides this attack into three stages: the exploit vector (e) where the machine being attacked is still running its vulnerable code, the bogus control data (γ) that is the part of the attack that is directly involved in control flow hijacking, and the payload (π) where the worm code is being executed instead of the code of the attacked system.
The Epsilon-Gamma-Pi model will be defined more formally in Chapter 3. In this document the particular focus will be on control data attacks, but the model generalizes to hijacking of control flow at any level of abstraction. What we will show in this dissertation is that malware analysis put into the context of the Epsilon-Gamma-Pi model can take advantage of various limitations placed on the worm at each of the stages. Researchers and malware analysis professionals can benefit greatly from an understanding of the differences between the stages in terms of the adversarial model, the polymorphic and metamorphic techniques to evade signature detection, and the amount of information about the threat that can be discovered in a particular stage. Three specific examples are described in detail: Minos, an architectural mechanism to catch control data attacks in the γ stage; DACODA, a tool to analyze attack invariants that limit polymorphism in the e stage; and Temporal Search, a method to analyze the π stage and discover timebomb attacks in a worm's payload.


This paper mainly studies process of dynamic routing in a multilevel perspective the mobile radio network based on the new generation of radio enhance the mobility a new and higher quality of service is required for different types of traffics,The Routing protocol in data networks will understand a formal set of rules and agreements on sharing network information between routers to determine the route of data transmission that satisfies a given quality of service requirements and provides a balanced load across the mobile radio network as a whole. including routing issues, devoted to the work of scientists, For modern computer networks of large dimension is typical multilevel routing in which in some way divided into a subnet routing domains, with at the most efficient protocol subnets group IGP, EGP group and protocols between networks. It is proposed to use a well-known proactive routing protocol OLSR multipoint handoff service packages as part of a hybrid protocol (HWMP). The description, the algorithm and the features of the implementation of the proactive protocol (OLSR).


Compared with the traditional strategy,green innovation strategy has transferred from the simple pursuit of economic benefit to the pursuit of economic,environmental and social benefit together.This change makes the knowledge that producing competitive advantage existing outside of the company,especially in the edge of the network of the company's stakeholders.But,existing theory and practice are still concerning about well known,prominent and influential actors.Recognizing this challenge,using the jute green strategy of Jiangsu Redbud Technology Co.Ltd.as a case,this paper developed the management method of edge strategy stakeholder of green innovation strategy: ① Outward expansion: based on action research,helping enterprises find a stakeholders group,small but representing different knowledge and value.② Inward deepening: creating value shared model of the enterprise and edge stakeholders,promoting the theory and practice development of tstakeholders.


Abstract : This is the final report for Classifying the Quantum Phases of Matter, FA8750-12-2-0308. Among other achievements, we made progress toward the following goals: (1) finding a classification of locally definable quantum states (those without symmetries or long - range entanglement), (2) elucidating the properties of three-dimensional quantum codes (in particular those which admit no string - like logical operators. (3) characterizing symmetry-protected fermionic phases, (4) proving the stability of topological phases of matter with respect to generic perturbation.


This research focused on the development of a rigorous process model of struvite crystallisation in order to address the issue of nutrient removal and recovery from wastewater. The model is based on a dynamic mass balance, coupled to a population balance, incorporating nucleation, crystal growth and aggregation rate mechanisms. These rate mechanisms were dependent on the thermodynamic driving force known as the saturation index. Non-ideal solution thermodynamics were employed to accurately describe the synthetic solutions employed in the experimental studies, enabling determination of the saturation index. Each rate mechanism had two uncertain parameters, namely the rate coefficient and the order of the power-law relationship. The model incorporated a discretised population balance that enabled the simultaneous coupling of nucleation, growth and aggregation mechanisms to the material balance.

The model equations were solved using gPROMS process simulation software.

A series of seeded, batch experiments covering a saturation index range of 0.75-0.25 was carried out to generate a data set that was used to regress the unknown kinetic rate parameters, thus completing the model description. The regressed parameters are presented below. Where, kᵢ is the rate coefficient for mechanism i and nᵢ is the order of the power-law relationship to saturation index. The parameters apply to atmospheric pressure and the temperature at which the experiments were conducted, being 29.3±0.6°C.

Aggregation: kᵢ = (3.72±0.014)×10⁻⁷ L/min; nᵢ = 5.26±0.004

Crystal Growth: kᵢ = 12.49±0.061 μm/min; nᵢ = 5.06±0.005

Nucleation: kᵢ = (8.50±0.076)×10⁷ 1/L.min; nᵢ = 1.68±0.014

A number of innovations and novel contributions resulted from this work.

Innovations:

• Application of rigorous process modelling to the issue of nutrient recovery, leading to;

•• embedded rigorous thermodynamics within a process modelling framework

•• improved understanding of the dynamic performance of nutrient recovery systems, based on struvite precipitation

•• a better understanding of the interplay of the mechanisms of nucleation, crystal growth and aggregation

•• performance assessment of nutrient recovery

• A framework is now in place to refine the model, through the addition of extra experimental data and/or to consider additional effects, such as hydrodynamics

Novelty:

• A hybridisation of the two-term and three-term discretised growth rate equation used in the DPB (Discretised Population Balance), leading to;

•• a solution method for a dynamic MSMPR (Mixed Suspension Mixed Product Removal) crystalliser that conserves particle volume without requiring an adjustable discretisation scheme

•• a description of the true nucleation rate, removing the need to guess a source function.

This research provides a modelling framework for designing struvite crystallisation systems from the position of understanding the kinetic mechanisms responsible for producing the crystal product. Using this approach will result in a better understanding of currently employed struvite crystallisers so that improvements can be made. More importantly, new designs can be tested and optimised through process modelling, instead of through the construction and operation of costly pilot plants.


The tribological properties of a custom-prepared and stable nano-lubricant that consists of CuO nanoparticles (9nm average diameter) suspended in mineral base oil using sodium oleate (SOA) as a surfactant are presented. Nano-lubricants with concentrations of 0.5, 1.0 and 2.0%wt were investigated using a disk-on-disk friction and wear test. It is observed that CuO/SOA nanoparticle additives reduce the friction between the lubricated surfaces in the absence of any other conventional additives. The effect of nanoparticles is more influential at higher loads and concentrations. Also, the steady state temperature of the lubricant is lower in the presence of nanoparticles. Measurements show that the viscosity of the nano-lubricants increases as more nanoparticles are introduced in the lubricant. The Stribeck curve is utilised to generalise the friction, temperature and the viscosity results into a single plot which can help to compare the performance of different nano-lubricants. Wear analysis based on profilometry results suggests that the wear increases with the nanoparticle concentration up to a 1.0%wt and then decreases for a 2.0%wt nano-lubricant. SEM/EDS results suggest that nanoparticles bond to the surface and form protective layers. Based on the results, different possible mechanisms for nanoparticles in the boundary lubrication regime were evaluated and the reduction in the real area of contact was suggested as the possible mechanism for reducing friction.


In this paper, rod drawing process of strain-hardening materials is investigated by analytical, numerical and experimental methods. The classic upper bound solution, based on the assumption of perfect plasticity, has been extended to consider the work-hardening of the material during the drawing process. For a given process conditions and mechanical properties of the rod material, the power terms and the required drawing force are determined and optimized with respect to the die angle. The results afforded by this solution agree with data from finite element simulation, using the finite element code DEFORM 2D, and some experiments performed by the authors. It is shown that the drawing force and the optimum die angle are affected primarily by the work-hardening exponent. The amount of drawing force increases as work-hardening of material considers in the analytical solution and by increasing the work-hardening exponent, the drawing force and the optimum die angle are decreased. It is also shown that by increasing the work-hardening exponent of the rod material, the maximum possible reduction in area is increased.


Summary 1. Neo-synephrine base is soluble in peanut oil containing oleic acid. 2. Neo-synephrine in oil injected subcutaneously or intramuscularly brings about a more sustained rise in blood pressure than does a similar injection of an equivalent amount of aqueous neo-synephrine HCl. 3. The threshold dose for both forms of neo-synephrine is about 0.05 mg/kg in the dog. Maximal responses are usually obtained with doses of 0.5 mg/kg by either subcutaneous or intramuscular injection. The latter dosage level is not well tolerated and is frequently followed by undesirable side reactions. 4. Neo-synephrine in oil is 28% less toxic than the aqueous neo-synephrine HCl equivalent. The slower rate of absorption from oil is the probable cause for the lower toxicity.


1105 Background: There is limited data on the long-term outcome of patients with microinvasive breast cancer. Moreover, predictors of lymph node involvement and the impact of multifocal microinvasion are not well understood. We examined the occurrence of nodal metastasis and the significance of multifocality on disease recurrence. Methods: Patients with T1mic breast cancer, defined as tumors ≤1mm, surgically managed at our institute between 1995-2010 were identified. Specimen slides were independently reviewed. Multivariable analysis (MVA) was used to predict lymph node involvement and disease recurrence. Results: Fifty-two patients with T1mic breast cancers were identified. Median patient age was 53 (range 30-92), median size of in-situ disease was 3cm (range 0.1-12cm). Ten patients (19.2%) had multiple foci of microinvasion (range 2-7). The majority of tumors were high-grade (76.9%). When the invasive tumor component was evaluated, 31 of 41 (73.8%) were ER positive, 40.5% were HER2+(15/37), and only one...


The development of audiovisual speech perception was examined in this experiment using the McGurk paradigm (McGurk and MacDonald, 1976), in which a visual recording of a person saying a particular syllable is synchronized with the auditory presentation of another syllable. Previous audiovisual speech studies have shown that adult perception is strongly influenced by the visual speech information whereas the perception of young children (5–8 years) shows a very weak influence of visual speech patterns and a strong bias favoring the auditory speech information. In this investigation 46 children in four age groups (5, 7, 9, and 11 year olds) and 15 adults were presented with conflicting audiovisual syllables in which an auditory /ba/ sequence was combined with visual /va/, /θa/, /da/, and /ga/ sequences, respectively. The results indicated that the influence of auditory information decreased with increasing age, while the influence of visual information and the integration of auditory and visual information ...


Purpose
This paper aims to contemplate the past development of backpacker tourism research and assess the future development of backpacker tourism research.

Design/methodology/approach
The authors evaluate the research on backpacker tourism in the past in the following three aspects, namely, research themes, research methods and geographical and cultural contexts of research.

Findings
Backpackers and backpacker tourism have been evolving in the past 75 years, just as other groups of travelers and forms of travel have. With the rapid pace of globalization in our time, backpacker tourism and its kinship forms will remain an important international tourism phenomenon, with root reasons in different types of economies and societies. As such, it will remain to be a significant research subject for tourism researchers in the future.

Originality/value
This paper contemplates the past development and assesses the future development of backpacker tourism research.


Mathematical modeling of non-pharmaceutical interventions (NPIs) of COVID-19 in Kenya is presented. An SEIR compartment model is considered with additional compartments of hospitalized population whose condition is severe or critical and also the fatalities compartment. The basic reproduction number (R_0) is computed by next generation matrix approach and later expressed as a time-dependent function so as to incorporate the NPIs into the model. The resulting system of ordinary differential equations (ODEs) are solved using fourth-order and fifth-order Runge-Kutta methods. Different intervention scenarios are considered and results show that, implementation of closure of education insitutions, curfew and partial lockdown yield predicted delayed peaks of the overall infections, severe cases and fatalities and subsequently containement of the pandemic in the country.


In the case of CVT (Continuously Variable Transmission), employing 3 K-type planetary gears, being manufactured, the speed of the output shaft of the CVT can be changed continuously from zero up to high speed. In this report, the construction of automatic transmission (RX-AT) has been designed incorporating this CVT, and the normal force has been set to make RX-AT transmit the power without slippage. After the equation of the rating life was determined by the experiments, the size of the RX-AT was determined by this equation and the normal force. Furthermore, from the result of manufacturing the experimental model RX-AT, a RX-AT more compact than conventional automatic transmission has been realized.


The roles of c‐erbB‐3 gene and protein in the pathogenesis, progression, and outcome of oral carcinoma remain unknown. To determine whether c‐erbB‐3 expression could serve as an indicator of progression from premalignant to malignant transformation and of prognoses in patients with oral carcinoma, the authors examined the relation between the expression of c‐erbB‐3 protein and cell proliferation activity during the development of oral verrucous carcinoma (VC).


Synchronization problem of a financial chaos system is investigated. Three linear control schemes are given to synchronize a chaotic financial system. We only use simpler controllers to realize global asymptotical synchronization. Therefore this can be viewed as an improvement to the existing results. In the first scheme,the sufficient condition for achieving synchronization of two financial system using linear feedback control is derived by using Lyapunov stability theorem. In the last two schemes,the synchronization conditions are obtained by numerical method. Numerical simulation results show the method given in this paper is effective.


Background: Stroke remains the leading cause of death and disability worldwide. This fact highlights the need to search for potential drug agents that can reduce stroke-related brain damage. Rifampicin is an antibacterial agent that is widely used in tuberculosis and leprosy therapy. Recent studies have found that rifampicin has neuroprotective properties in neurodegenerative diseases. In this study, we investigate the effect of rifampicin on spatial memory deficits, neuronal damage and also evaluate mitochondrial changes caused by ischemia/reperfusion (I/R) in rats.


The paper concerns lattice triangulations, i.e., triangulations of the integer points in a polygon in R2 whose vertices are also integer points. Lattice triangulations have been studied extensively both as geometric objects in their own right and by virtue of applications in algebraic geometry. Our focus is on random triangulations in which a triangulation σ has weight λ|σ|, where λ is a positive real parameter and |σ| is the total length of the edges in σ. Empirically, this model exhibits a "phase transition" at λ=1 (corresponding to the uniform distribution): for λ<1 distant edges behave essentially independently, while for λ>1 very large regions of aligned edges appear. We substantiate this picture as follows. For λ<1 sufficiently small, we show that correlations between edges decay exponentially with distance (suitably defined), and also that the Glauber dynamics (a local Markov chain based on flipping edges) is rapidly mixing (in time polynomial in the number of edges). This dynamics has been proposed by several authors as an algorithm for generating random triangulations. By contrast, for λ>1 we show that the mixing time is exponential. These are apparently the first rigorous quantitative results on spatial mixing properties and dynamics of random lattice triangulations.


Transverse spatial degrees of freedom of photons are mapped onto a spin ½ system. This task can be accomplished by dividing the transverse space into two semi-planes, and using fractional Fourier transform operations as rotations.


Let $\mathbb{N}_0$ be a class of natural numbers whose binary expansions contain even numbers of ones. Waring problem in numbers of class $\mathbb{N}_0$ is solved.


The utility model discloses a combined double preheating heat-storage type burner, comprising a furnace body. Both sides of the furnace body are provided with a heat storage type air burner nozzle and a heat storage type gas burner nozzle. The heat storage type gas burner nozzle and the heat storage type air burner nozzle are respectively communicated with a furnace chamber. The inner cavities of the heat storage type air burner nozzle and the heat storage type gas burner nozzle are respectively filled with a heat accumulator. The heat storage type air burner nozzle and the heat storage type gas burner nozzle are in parallel arranged. An electronic ignition gun is arranged between the heat storage type air burner nozzle and the heat storage type gas burner nozzle on both sides and is extended to the furnace chamber. The utility model can achieve high-temperature air combustion. Compared with other heat engineering equipment of the same dimension, the utility model increases mean temperature in the furnace and production, and reduces fabrication cost of the equipment. The emission of the nitrogen oxide and the carbon dioxide is reduced greatly through the poor oxygen combustion organized, so that the air pollution can be reduced.


-------------------------------------------------------------------ABSTRACT-------------------------------------------------------------In Today's, Security are a big and challenging issues, for where the information has been transmitted. There are lots of techniques come in existence, but most of them are struggle against hackers and unauthorized users from last many decades. There are two most popular and reliable techniques has been used for security, these are Cryptography and Steganography, but now a days hackers are become more advanced and they have a lot of tools to break it. Therefore we have the requirement for more advance and trusted techniques, that have more strength compare to Cryptography as well as Steganography. This paper is based on a model for performance enhancement of Steganography techniques through new advance technique Dynamic key Cryptography.


ObjectiveTo investigate the regulation of Chinese herbs and nitric oxide (NO) on the peritoneal lymphatic stomata and elucidate the mechanism of Chinese herbs on the treatment of ascites.Methods Scanning electron microscope and computer image processing were used to detect the diameter, area and open density of the stomata, and sodium ion concentration in urine was measured. Results (1) The diameter, area and open density of the stomata was increased, and the output of sodium ion from urine were obviously enhanced in Chinese herbs group (P0.01); (2) In NO donor (sodium nitropusside) group, the diameter, area and open density of the stomata were markedly increased (P0.01or P0.05); (3) Based on the effects of Chinese medicinal herb, NO inhibitor (L-nitroarginnine) was given to mice. The diameter, area and open density of the stomata were obviously decreased (P0.01).Conclusion This Chinese medical herb can regulate the stomata and enhance the output of ascites, and the results showed that Chinese herbs can probably rise the concentration of internal-derived NO and make the stomata open so as to make the drainage of ascites from the peritoneal cavity.


Catalysts and catalyst carriers, as granules having a shape GEOMETRIC DEFINED characterized by porosity values such that at least 70% of the volume of pores having a radius corresponding to the values MAXIMUM CURVE porosity distribution . Catalysts and shaping them CARRIERS ARE OBTAINED BY COMPRESSION, IN WHICH THE EMPLOYEE LUBE APPLY TO SURFACE molding chamber (LUBRICACION EXTERNAL).


A new polariser composed of two pieces of substrates coated on one surface with split-ring resonators to realise a 90° polarisation rotator is presented. Based on the accurate design of material parameters, high conversion efficiency and 20% frequency bandwidth are achieved. Microwave experiments were performed to successfully realise these ideas and results are in excellent agreement with numerical simulations.


Three out of four patients with prostate cancer with an 18F-choline positron emission tomography/computed tomography–detected recurrence were potentially salvageable with local therapy or metastasis-directed therapy (MDT), according to results of the screening phase of the phase II STOMP randomized trial.


This paper presents a 10-bit 120MS/s SAR ADC. A novel reference ripple cancellation technique is proposed to address the reference settling issue during high-speed DAC switching. Instead of consuming power/area to ensure a fast recovery or small ripple, it provides a feed-forward path for the reference ripple and performs cancellation at the comparator input, thus guaranteeing a ripple-free signal. A 5-bit dedicated DAC is configured to emulate the ripple transfer function of the main DAC. A 40nm CMOS prototype achieves a Walden FoM of 15fJ/c-s while requiring only 3pF decoupling capacitor.


The flexible job shop scheduling is the problem that found in the manufacturing industry and challenge for many researchers interested in this field. This paper proposed new algorithm for solving the flexible job shop scheduling problem (FJSP). The proposed algorithm is based on the flower pollination algorithm with a new concept called disparity count process. The performance of the proposed algorithm is compared with the other state-of-the-art metaheuristic algorithm. The results are evaluated in terms of the average percentage deviation from the lower bound. The experimental shown that the proposed algorithm found the number of best answer more than others algorithm.


Objective: To study the effect of the water extract of Fagopyrum dibotrys on COPD model of rats with pulmonary fibrosis. Methods: Rats were randomly divided into normal group,model group, and Fagopyrum dibotrys water-extraction low and high dose groups. Pathological morphological changes of lung and bronchus were observed. The expressions of MMP-9 and TIMP-1 were detected by immunohistochemistry method. The expressions of TGF-β and PⅢ were detected in serum supernatant by radioimmunoassay method. Results: Compared with normal group,Fagopyrum dibotrys water extract had significant improvement effect on the lung and bronchus pathomorphism changes of rats,especially in high dose group and inhibited excessive expressions of MMP-9/ TIMP-1,increased the expression of MMP-9/TIMP-1,and decreased the expression of TGF-β and PⅢ in serum. Conclusion: Fagopyrum dibotrys water extract can improve the COPD model of rats with pulmonary fibrosis.