Objective To study traditional Chinese medicine syndromes of the patients with senile dementia in the community.Methods The 143 patients with senile dementia in the community health service center and community station were given questionnaires and the data were analyzed by descriptive analysis. Results Among the 143 patients with senile dementia,the most basic traditional Chinese medicine syndromes were kidney deficient and encephala reduction,followed by heart and liver deficiency,sputum turbid blocking aperture,heart-spleen deficiency,qi-stagnancy and blood stasis,of which 77 cases were totally deficiency syndromes,17 cases were totally excessive syndromes and 49 cases were deficiency-excess complications. There were 70 cases of single syndrome,and the types were ordered from more to less as follows: kidney deficient and encephala reduction,sputum turbid blocking aperture,heart and liver deficiency,heartspleen deficiency,qi-stagnancy and blood stasis. There were 73 cases of composite syndromes,and the types were ordered from more to less as follows: kidney deficient and encephala reduction,heart and liver deficiency,sputum turbid blocking aperture,heart-spleen deficiency,qi-stagnancy and blood stasis. Conclusion The mechanism of senile dementia was complex and was induced by the interplay of many pathological factors. It was rare to be induced by a single mechanism. The basic mechanism of senile dementia was deficiency in origin and enrichment in symptom. For deficiency in origin,kidney deficient and encephala reduction were the most outstanding; for enrichment in symptom,sputum turbid blocking aperture played an important part.


Typical structural editor provides for syntax correctness of an edited text. In this paper some problems are discussed that arise when the semantic analysis is to be included in the tasks of a structural editor. The solution to these problems, already implemented in Modelang editor, is presented. It is based on the concept of multistage editing operations and application of default values. Several examples are given to show how the editor should deal with basic Pascal constructs in order to preserve full semantic accuracy. Additionally, two solutions are proposed to the problem of name maintenance within the structural editor. Structural editing versus conditional compilation is also considered.


A resonant optical excitation creates an excited state population and also induces an optical polarization. Dynamics of this optical excitation is characterized by relaxation of the population as well as decay of the induced optical polarization. In lower dimensional semiconductors, electronic confinement leads to qualitative changes in population relaxation, including spontaneous emission and exciton-phonon scattering, as shown in extensive recent studies [1]. These population relaxation processes are expected to contribute to dephasing with a dephasing rate given by half the population decay rate. Pure dephasing processes that do not involve population or energy relaxation of excitons can also contribute to dephasing. Pure dephasing, which is a well-established concept for atomic systems, remains yet to be investigated in lower-dimensional semiconductors due to a lack of direct comparison between dephasing and population relaxation and between theory and experiment. Studies of pure dephasing processes in lower-dimensional semiconductors will renew and deepen our understanding of dephasing of collective excitations in solids, although several seminal studies were done on the exciton dephasing in quantum well (QW) structures [2–6].


The interaction of a four-level atomic system with two electromagnetic radiations has been studied. The two intermediate levels are closely spaced such that a single radiation frequency can induce transitions from the ground state to both of them. In a cascade-type double resonance, the pump electric-field amplitude is much stronger than the amplitude of the signal field, which can induce transitions from both of the intermediate levels to the upper state. The 15 optical Bloch equations obtained from the Liouville equations are solved analytically to obtain the Doppler-free signal line shape. The computed signals, exhibiting two Lorentzian line profiles, are presented for different pump frequencies. In addition to these one-photon transitions, we obtain a weak two-photon resonance peak


The path of a CO2 laser beam through a plasma is photographed by an image converter camera in conjunction with an interference filter. The filter was used to isolate a silicon impurity line the intensity of which was very sensitive to changes in plasma temperature produced by the absorption of the laser energy.


Although the systems architecture for intelligent vehicle highway systems (IVHS) is still being developed, it is certain that tetherless radio frequency (RF) communications will play a major role in the program. The portion of the RF spectrum suitable for mobile systems is very congested. New demands for use of these mobile bands are expected as promising technologies and services mature for commercial deployment. The authors describe strategies to identify suitable frequencies, to muster needed support from various communities, and to take appropriate actions for obtaining a spectrum for IVHS. In addition to the acquisition of frequencies for exclusive, nationwide use by IVHS, the authors evaluate existing and planned communications media that may be suitable for capacity sharing to yield still further communications capacity for some IVHS functions.<<ETX>>


In this paper, two approximate inertial manifolds for the nonlinear Schrdinger equation iet+~2ex~2+g(|e|~2)e+iαe+h=0 are constructed. The orders of approximations of the manifolds to the global attractor are derived.


N o matter how meticulous the cosmetic surgeon is when implanting silicone-gel or saline implants, different types of complications occur just due to the fact that a foreign object is placed within the body. Many times there are ways to reduce these problems but not to eliminate them. The surgeon must explain before surgery the risks and possible complications, especially those which may require further surgery for correction. It is incumbent on the surgeon to understand the causes of complications, how to limit the occurrences, and how to treat the problems. The implantation of silicone-gel prostheses is presently limited to the research study being run by Mentor HIS. Silicone-saline implants are still available with a smooth shell or a textured shell. Saline implants tend to be slightly firmer than the silicone-gel counterpart but saline implants also result in an increased projection ofthe breast. Some patients who have had gel implants replaced with saline prostheses appreciate the added breast projection. Since saline implants are filled to a point where the shell is smooth without folds, the prosthesis becomes rounded with sharper fall-off of the edges, which may give a more obvious appearance of the presence of a breast implant.


: Krishnappa, Kishore Kothapalli and Venkaiah [2009] analyzed (1)Kn, n odd, admits a vertex magic total labeling; (2) There is a vertex magic total labeling for K n , for all n ≡ 2 (mod 4); (3) There is a vertex magic total labeling for K n , for all n ≡ 4 (mod 8); (4) There is a vertex magic total labeling for K n , for all n ≡ 0 (mod 8). Subbiaha, and Pandimadevi [2014] found (1)eEvery 2rregular graph has a 2kfactor for every integer k,0 < k < r; (2) An even regular graph G of odd order is not 2-factor E-super magic decomposable, when the number of factors h is even;(3) An even regular graph G of odd order is 2factorEsuper magic decomposable if and only if h is odd, where h is the number of 2factors of G. Selvaraju, Balaganesan, Renuka [2013] made the contributions (1)D 2 (P n ) is an even sequential harmonious graph; (2) D 2 (K 1,n )is an even sequential harmonious graph; Spl(P n )is an even sequential graph;(4) The Spl(K 1,n )is an even sequential harmonious graph; (5) Spl(P n )is odd graceful graph; (6) D 2 (K 1,n )is felicitous graph. The aim of the paper is to find graceful labeling for the graphs P n *2nP 6 , P n *2nP 7 , and P n *2nP 8 .Keywords: Magic graph, super magic graph


Here the presented shape work are scalable, autonomous, robust and have absolutely job processing capability within a distributed environments, this framework are utilized in load controlling purpose in distributed systems, this devices is heterogeneous distributed system, and this system contain a centralized manager, this coordinator accustomed to manage the overall distributed system, and this also coordinator also examine the free processing nodes, and well as load of the available computing machine. The computing equipment are inter linked with high speed community or message driving bus, by the assistance of the bus data could be migrated from one computing machine to another computing machine, communication occur because of the high speed community.. The load controlling, fault tolerance along with failover recovery are meant into the system via a mechanism of wellness check facility and also a queue based load balancing. The basic element assigning a concern and processing according to priority is built into the framework. The most crucial aspect of the particular framework is who's avoids the dependence on job migration by computing the prospective processors good current load along with the various cost components. The framework will are capable to scale horizontally as well as vertically to effectuate the demand compliance, thus effectively minimizing the entire cost of title Keywords-Job Processing, Load equalization, loads Monitoring, Distributed and Scalable.


1. Introductory. 'If we regard language activity, in its formal aspect, as the repeated selection of one from among a number of possible events-or, so as to formulate it more simply, of items from sets of items which are "at risk" under certain conditions, the total selection situation (items and conditions) varies along a cline. At one end of the scale, there are a very large number of sets, in very complex interrelations, but with very few items in each: this is grammar. At the other end, there are few sets, in simple relations, but with large inventories of items making them up: this is lexis. There is no sharp line between them, though the extremes are clearly distinct. Since patterning of the first type lends itself to much greater abstraction, we can make the theory of grammar much more powerful than the theory of lexis. So the linguist tries to bring as much as possible of linguistic form into his grammatical statements-though there is a theory of lexis too, which has a part in the total description.'1 Thus, of the two demi-levels at the level of form, grammar can be supplied with a theory which is more compact and more intricately structured than any possible theory of lexis. And so a fully descriptive theory of grammar must be fairly complex. For this reason the methods and procedures of symbolic and other types of logic can be usefully employed in the statement of such a theory. In this way a statement can be made which is concise, complete and, most important, fully explicit. The nature of such a statement precludes any possible ambiguities which might be present in the reader's interpretation of a more discursive statement. This paper,2 then, presents a logical statement of the General Theory of Grammar which is described in M. A. K. Halliday's 'Categories of the theory of grammar', Word 17.241-92 (1961); sections 3 to 7 of that paper contain the nucleus of the theory and correspond to the present statement. Thus this statement is merely a rephrasing of the theory. Both Halliday's paper and the present one are concerned with the identical theory of grammar; it is only the methods of description which differ. The two statements will in fact complement each


As offshore wind energy is a new area for operations research , O&M cost modelling software tools are developed to support activities in this field. Lack of real data means there are limited options for verification of these models A step towards verification and increased model credibility is codeto-code comparison where model results are compared with those from other models [1-3]. • Develop and provide reference cases for model developers • Run reference cases with four models and present results • Identify and understand important modelling assumptions for estimating performance of the four O&M models and logistics strategies.


Background and Motivation Current requirements for future helicopters as outlined by the Future Vertical Lift, Joint Multirole and DARPA X-plane competitions all call for helicopters to fly at significantly higher speeds than they can currently achieve while maintaining exceptional hovering performance. The Sikorsky X2 has flown faster than 250 kts, demonstrating that the rigid coaxial compound is a viable candidate for future helicopter configurations. In addition to the performance benefits, the rigid coaxial compound provides significant freedom in trim allowing for hover and flight in a variety of pitch attitudes as well as the use of lift offsets in the rotor. This paper presents work that has developed a comprehensive analysis technique for analyzing coaxial rotors and is used to study the impact of coaxial configuration on performance and loads.


The cutoff frequencies of the rectangular waveguides are calculated using the technique of the Lagrange Multipliers. The application of the technique of analytical integration is made with the integrals written in the homogeneous coordinates of the finite element. The final system is badly conditioned, symmetrical and is not defined positive. We present a form to turn it out to be defined positive.


Objective: We have previously reported the characterization and regulation of interleukin-1 (IL-1) receptors utilizing [125I]IL-1 binding assay in male C57BL/6 mice and the mouse AtT-20 pituitary tumor cells. In the present study, we examine IL-1 receptors using an immunoblotting method to further characterize the mechanisms regulating the interactions of IL-1 receptors with endotoxin, lipopolysaccharide (LPS). Methods: We established Western blotting for IL-1 receptors using AtT-20 mouse pituitary tumor cells. Results: Several bands were seen; however, only the 105-kD band was neutralized with a 5-fold excess of IL-1 receptor- blocking peptides, suggesting that this band is specific for IL-1 receptors. Next, we investigated the effect of LPS and IL-1β on IL-1 receptors. Treatment of AtT-20 cells with 0.01 µg/ml of LPS did not affect IL-1 receptors. In contrast, 1 µg/ml of LPS significantly increased IL-1 receptors in AtT-20 cells compared with the control group. In addition, [125I]IL-1β binding was markedly increased followed by 1 µg/ml of LPS. In contrast, 1 nM recombinant human IL-1β significantly decreased IL-1 receptors in AtT-20 cells compared with the control group although treatment of AtT-20 cells with 0.01 nM IL-1β did not affect IL-1 receptors. LPS (0.1 and 1 µg/ml) did not affect IL-1β concentrations in the medium of AtT-20 cell culture. IL-1β concentrations in the homogenates from AtT-20 cells were significantly decreased after 1 µg/ml of LPS treatment but not after 0.01 µg/ml LPS. Conclusions: These data demonstrate that LPS and IL-1β differentially modulate IL-1 receptors in AtT-20 cells and LPS-induced modulation of IL-1 receptors may provide a novel mechanism for the actions of LPS to alter pituitary function during endotoxemia. Additional in vivo studies are necessary to determine the physiological relevance of this in vitro phenomenon.


In the fault diagnosis of modern industrial equipment, domain adaptation is widely utilized to address the challenge of data distribution changes. However, the traditional domain adaptation method only learns single-domain knowledge and experiences difficulty in coping with scenarios wherein working conditions change drastically. Accordingly, learning knowledge from multiple different source domains can effectively improve the generalization ability of the model and the reliability of the diagnosis results. Simultaneously, aligning marginal and conditional distributions can weaken data distribution differences caused by drastic changes in operating conditions, enabling more accurate knowledge transfer between source and target domains, and improving the performance of model cross-domain fault diagnosis. Furthermore, when the data comes from multiple different domains, completely aligning all source domains is arduous and impractical, and thus, selectively synthesizing different source domain migration diagnostic results is necessary. To address the aforementioned issues, this study proposes a multibranch weight-adaptive adversarial fault diagnosis method. This method uses multiple branch networks to match each source–target domain pair independently, aligns them as much as possible with two domain confusion networks, and calculates the alignment degree to assign the source domain weight coefficient. The final fault diagnosis result is obtained by synthesizing the domain classifier results that correspond to the weighted coefficient domain. Experiments verify the reliability and stability of this method under various working conditions, such as high span speed and variable speed.


Invasive species can have major disruptions on native food webs, yet the impact of species introductions and whether they will become invasive appears to be context-dependent. Rainbow smelt and alewife co-exist as invasive species in the Laurentian Great Lakes and as native species on the Atlantic coast of North America, but in Lake Champlain rainbow smelt is the dominant native forage fish and alewife are invasive. Alewife became abundant by 2007, providing an opportunity to explore the dynamics of these two species in a system where only one is invasive. We used data from a 31-year forage fish survey to compare demographics of rainbow smelt populations in three basins of Lake Champlain with different pelagic volumes, nutrient levels, and predator abundances. Rainbow smelt catch-per-unit-effort (CPUE) remained constant in the large, deep Main Lake before and after alewife invaded, but decreased in the two smaller basins. Declines were primarily a result of increased age-0 and age-1 mortality. Predation by top piscivores, system productivity, and resource competition alone could not explain the patterns in CPUE across the basins. The mechanisms that allow alewife and rainbow smelt to co-exist could be related to system volume and oxythermal habitat availability, and may explain why the two species do not negatively affect each other in other systems. Summer hypoxia in the smaller basins could force individuals into smaller habitat volumes with higher densities of competitors and cannibalistic adult smelt. Our findings suggest that habitat size mediates the impact of invasive alewife on native rainbow smelt.


This edition is a considerable addition to the lute repertory that is easily accessible to scholars without full understanding of tablature notation; it will also be welcomed by players of the lute, as modern tablature is provided for the entire contents (including one fantasia that survives uniquely in staff notation). Collected here are 26 pieces, mostly fantasias, of unquestionably Neapolitan origin, composed in the second half of the 16th century; a further five pieces are appended which are attributed to Fabrizio Dentice in a late source, but had been published earlier (1566) by Melchior Neusidler without any suggestion they were not his own work. Each lutenist featured in this volume had a high reputation in his own time; they were all named and praised in a list of famous Neapolitan lutenists in Scipione Cerreto's Della practica musica (Naples, 1601). The two principal composers, Fabrizio Dentice and Giulio Severino, however, were not just lutenists, but skilled composers of contrapuntal vocal music, as is evident in their works for lute. When playing through their finely-wrought fantasias, one frequently has the impression of taking part in a performance of vocal music whose words have been lost. Indeed, this may be the key to their correct interpretation, for they are not showy works of instrumental display, although they demand a good deal of technical skill. By nomeans are these pieces for beginners on the instrument. This volume shows the importance of Naples within the history of the lute and its repertory. As is well known, there were strong political and cultural connections between Naples and Spain in the 16th century. One musical consequence of these connections was that the viola da mano (the instrument the Spanish called the vihuela) co-existed with the lute in Naples throughout the period. Francesco da Milano's work was published in Naples in editions explicitly designated for viola from as early as 1536 (two books, possibly his first music to appear in print); his most important student, Perino Fiorentino, worked there during the 1530s, and undoubtedly helped to foster the high standard of lute playing that is amply documented in this new collection. Furthermore, the earliest Italian treatise on playing the lute and arranging music for the instrument, Lieto's Dialogo quarto, was published in Naples in 1559. And in the extensive Neapolitan archives there is no shortage of documentary records of performances on and teaching of the viola and lute. The most interesting figure featured in this volume is Fabrizio Dentice (c.1530–1581). As an aristocrat he had no need to earn a living by performing or teaching, which may explain the general lack of sources of his music from his lifetime. (A generation later, Carlo Gesualdo, Prince of Venosa, who was well known as a lutenist, left posterity no works for the instrument at all.) His father, Luigi Dentice (c.1510–1566), who served the powerful Sanseverino family, had a great reputation as a singer and lutenist, and as a consequence the biographies of father and son are hard to disentangle. In 1540 Luigi turned down a request to serve Henry VIII of England for 1,000 crowns a year. In 1552, some years after Luigi had spoken out in support of an attempted coup against the Spanish viceroy, Pedro de Toledo, the Dentices fled to Rome, where they rapidly established themselves in aristocratic and artistic circles and helped to import a novel vocal genre that soon became highly fashionable, the villanella alla napolitana. After Pedro de Toledo's death in 1553, the Dentices were pardoned and Fabrizio probably visited Spain, performing daily at the royal court. Contact with the new king of Naples led to a move to Milan (where the king was governor) in or shortly before 1562. Then followed several more visits to Rome and Spain, where in 1564 the Englishman Thomas Chaloner wrote to Sir Robert Dudley, the English envoy, about Fabrizio: 'The young man Fabricio, a gentleman Neapolitan of a seemly personage was with me in my lodging. I heard him both play and sing; his play for clean handling and deep music and parts withal and excellent fingering in time and place, is incomparable of any that ever I heard.


This paper describes a timing-skew calibration technique which equalizes the phase spacings among multiphase clocks. The scheme uses simple sample-and-hold circuits controlled by the multiphase clocks to sample a common reference input. Phase spacing is measured by counting the number of zero crossings between two adjacent sampling sequences. A zero-crossing detection scheme is proposed. It has better immunity against the offsets of the comparators used in the detector. A digital calibration processor is also proposed. It examines the outputs from the zero-crossing detectors, and then adjusts the delays of clock buffers in order to minimize timing skews. The proposed calibration scheme does not demand stringent requirement for the reference input. Its application to a eight-channel 6-b time-interleaved analog-to-digital converter is demonstrated.


Solutions of the stationary semilinear Cahn--Hilliard equation
-\Delta^2 u - u -\Delta(|u|^{p-1}u)=0 in R^N, with p>1, which are exponentially decaying at infinity, are studied. Using the Mounting Pass Lemma allows us the determination of two different solutions. On the other hand, the application of Lusternik--Schnirel'man (L--S) Category Theory shows the existence of, at least, a countable family of solutions.
However, through numerical methods it is shown that the whole set of solutions, even in 1D, is much wider. This suggests that, actually, there exists, at least, a countable set of countable families of solutions, in which only the first one can be obtained by the L--S min-max approach.


The present work is focused on the kinetic study of hydromagnesite thermal decomposition carried out by constant rate thermal analysis technique at 5 hPa partial pressure. The apparent activation energies were measured experimentally all along the decomposition without any assumption about the rate law of the determining step. Under these conditions the decomposition of hydromagnesite occurs in two steps. The first step is a dehydration which occurs with apparent activation energy of 60 kJ.mol -1 and D4 kinetic model. The second step is essentially decarbonatation, which occurs according to an F1 kinetic model and activation energy equal to 95 kJ.mol -1 .


Objective To observe the clinical effect of overall care of mental state and childbirth in early maternal.Methods 190 cases of primipara were randomly divided into intervention group and control group,each of 95 cases.Control group received conventional therapy and intervention group was given with the overall care measures.Compared the self-rating anxiety scale(SAS) and depression scales(SDS) score and outcome of pregnancy of two groups.Results After treatment,SAS and SDS scores in intervention group were lower than pre-treatment and control group(P0.05).The rate of cesarean delivery,neonatal asphyxia incidence in intervention group were lower than control group(P0.05).Conclusion The overall care can improve the psychological state and pregnancy outcomes of the early maternal.


Introduction:
 Previous studies have shown that women have poorer neurological outcomes than men following out-of-hospital cardiac arrest (OHCA). However, those studies focused on survival, a measure that may be confounded by withdrawal of life-sustaining therapy (WLST) decisions. We sought to assess sex differences in severe cerebral edema development following cardiac arrest.

 Methods:
 Data from adult OHCA patients presenting between 2007-2019 were retrospectively analyzed. Patients with multiple concomitant acute neurologic dysfunctions were excluded. Severe cerebral edema was classified as herniation or more than minimal ventricular effacement in MRI or CT radiology reports. Arrest types were categorized as shockable (VT/VF) or non-shockable (PEA, asystole). Poor outcomes were defined as Cerebral Performance Category > 3 at discharge. Multivariable backward stepwise logistic regression was performed.

 Results:
 359 patients met our inclusion criteria. Demographics, imaging and clinical outcomes are summarized in Table 1. Women were more likely than men to have a non-shockable initial rhythm (P=0.003) and develop severe cerebral edema (P=0.005). Backwards stepwise logistic regression of an initial model including age, sex, rhythm, witnessed arrest and TTM-treatment, produced a final model that showed younger age (P<0.001), female sex (P=0.01), and non-shockable rhythm (P<0.001) as significant predictors of severe cerebral edema development. Patients with severe cerebral edema had worse outcomes (89/91 vs 176/268, P<0.001), and greater in-hospital mortality (82/91 vs 166/268, P<0.001), with a higher proportion of deaths due to brain death (15/82 vs 3/166 P<0.001).

 Conclusion:
 For OHCA patients who are initially comatose, women are more likely than men to have non-shockable rhythms and severe cerebral brain edema. These differences may be responsible for the poorer discharge outcomes that have been observed by other studies.


1 Scoville SA, Buskirk TD. Traditional and virtual microscopy compared experimentally in a classroom setting. Clin Anat 2007;20:565–70. 2 Ludmerer KM. Time to Heal. American Medical Education from the Turn of the Century to the Era of Managed Care. Oxford: Oxford University Press 1999. 3 Bloodgood RA, Ogilvie RW. Trends in histology laboratory teaching in United States medical schools. Anat Rec B New Anat 2006;289B:169–75.


In view of the problem of inaccurately measuring the gross calorific value of coal, this paper analyzed the relationship between industry analysis data and calorific value of fire coal into the furnace, and five kinds of industrial analysis components were selected as the original independent variables, which were moisture, ash, volatile matter, sulphur content and fixed carbon in fire coal. In the process of modelling, the latent variable factors were extracted by the partial least square regression method, and the latent variables were selected as the input vectors and coal-fired calorific value as the output vector, then the power plant coal calorific value forecasting model was built based on support vector machine regression algorithm. The predicted results showed that, the accuracy of the coupled model was higher than that of the single model and the forecasting deviations met engineering requirements. Therefore, the model proposed here has practical engineering application value. At the same time, in the process of modelling, the five-point method was used to determine the optimal combination of penalty coefficient and kernel coefficient in the process of modelling. The method could quickly and accurately determine the optimal combination and avoid the blindness of the traditional method in the process of determining the optimal combination of penalty coefficient and kernel coefficient.


On behalf of my co-authors, we thank you very much for giving us an opportunity to revise our manuscript, we appreciate editor and reviewers very much for their positive and constructive comments and suggestions on our manuscript entitled "Non-alcoholic Wernicke encephalopathy in an esophageal cancer patient receiving radiotherapy: A case report and literature review". (ID: 73666). We have studied reviewer's comments carefully and have made revision which marked in red in the paper. Attached please find the revised version, which we would like to submit for your kind consideration. We would like to express our great appreciation to you and reviewers for comments on our paper. Looking forward to hearing from you. Thank you and best regards. Yours sincerely,


This paper addresses a novel slip-ratio-based torque distribution strategy for electric vehicles (EVs) to avoid slippage when driving over a split friction surface. With the combination to an upper and middle controller, the desired driving force and yaw moment can be distributed to four driving wheels by utilizing the proposed lower controller. Stability analysis by using Lyapunov theorem is presented to show that the distribution method can equalize the slip ratios for the wheels on the same side of EVs. In addition, we also propose two torque distribution parameters for driving force Kf and moment Km so that it is more flexible and easier to design a lower controller for EVs. This distribution method is able to equalize the slip ratios for wheels on the same side of EVs, so that the slipping motion can be avoided. Simulation results by using CarSim and MATLAB/Simulink are presented to show the performance of the proposed methods.


Our country's prison production plays an important role in promoting criminals reform,maintaining social stability and propelling prison cause forward.With the establishment and perfection of our country's socialist market-oriented economy system,it is imperative to reconstruct prison production's ideal model and research on its development.Combining with the existing problems of our country's prison production system,this article discusses the main ways and methods of reconstructing our country's prison production system.


This paper presents a hybrid passive wireless resonant electrical and mechanical sensor for enhanced sensitivity and specificity. Mechanical resonance measures the viscosity and electrical resonance measures the dielectric properties of liquid samples. The sensor is composed of two magnetoelastic (amorphous ferromagnetic ribbons) strips placed in parallel that are separated with a dielectric spacer forming a capacitor. An inductive coil is attached in parallel to this capacitor leading to an electrical resonant inductive-capacitive (L-C) tank. Both mechanical and electrical resonance frequencies are wirelessly measured using a single pickup coil hooked to an impedance analyzer. Several liquid samples, including food items, having different viscosity and dielectric properties are measured and key advantages of this sensor are demonstrated. This sensor can be used in food quality monitoring and can be integrated with passive RFIDs.


Accurate electricity demand forecasting for daily peak load is essential for management and planning at electrical facilities. In this paper, we first, introduce the several time series models that forecast daily peak load and compare the forecasting performance of the models based on Mean Absolute Percentage Error(MAPE). The results show that the Reg-AR-GARCH model outperforms other competing models that consider Cooling Degree Day(CDD) and Heating Degree Day(HDD) as well as seasonal components.


This project of designing and building a prototype of a teh tarik machine is
divided in two parts. First part of the project is about proposal and the second part is
about producing the prototype of the machine. This report fully describes about the
combination of both part, which contains six chapters starting from introduction,
literature review, methodology, results, discussion and conclusion respectively. The
main objective of the project is to design and build a prototype of a machine. The
conceptual design has been done through sketching by using free hand. After that,
the design of the machine was being created by using software such as AutoCAD or
CATIA. The process of manufacturing has been done after completing the assembly
design in software. This machine has been done by using stainless steel for the body
part. Meanwhile, there was also electrical circuit that has been inserted in the
machine. This electrical circuit consist of heater element and blender function. The
both of the part has been combined together and used to produce the "teh tarik"
beverage.


Introduction: Knowledge regarding the effects of laparoscopic adjustable gastric banding (LAGB) on resting metabolic rate (RMR) and the hormonal milieu is limited. Our study aimed to determine how LAGB impacts RMR and hormonal response to a meal. Methods: Twenty-five patients were enrolled. Patients were seen before and two months after surgery. At each visit, RMR was measured and blood was collected fasting and after drinking Ensure to measure hormonal levels including glucagon-like peptide 1, gastric inhibitory polypeptide, peptide YY, ghrelin, pancreatic polypeptide, leptin, insulin and amylin. Results: Of the 25 patients, 17 completed the study, 1 completed RMR only, and 7 dropped out. Mean weight loss was 12.3 kg ± 4.9 and mean percentage of excess BMI loss was 22.6% ± 9.9. Median RMR before and after LAGB decreased significantly. Decrease in RMR correlated with amount of weight loss. Median fasting leptin and ghrelin levels decreased pre- and post-LAGB, but ghrelin did not reach significance. No differences were seen in hormonal response to a meal. Conclusion: Weight loss after LAGB resulted in decreased RMR, fasting leptin levels and possibly lowered ghrelin. Further studies are needed to delineate the long-term effects of LAGB on metabolic rate and the hormonal milieu.


UDP‐xylose (UDPX) is the substrate used for xylosylation in most organisms. Xylosyl residues are components of vital molecules in the cell walls of plants and bacteria and in the extracellular matrices of animals. Despite the proliferation of xylosylated compounds, UDPX is a markedly expensive chemical which limits research potential into these areas. It is known that the pair of enzymes UDP‐glucose dehydrogenase (UGD) and UDPX synthase (UXS) can catalyze the set of reactions leading from UDP‐glucose, a much cheaper chemical, to UDPX. This project optimized the enzyme assay of both UGD and UXS to improve the efficiency and rate of UDPX synthesis in order to develop an economical means of producing UDPX. Additionally, the kinetics of the previously uncharacterized UGD and UXS isoforms used in the assay were investigated.


Image fusion in remote sensing is an issue to fuse the texture information of panchromatic (PAN) channel and the spectral information of multispectral (MS) channels with lower spatial resolution (LR). In this paper, a method named SPCA is proposed to deal with image fusion from the perspective of sparse representation and PCA, in which the correlations both within and between channels are effectively modeled. First, the sparse representation theory is applied to remote sensing images. Second, the dictionaries of PAN and MS images are joint-learned, and a thought of PCA is applied to construct dictionaries of MS images of high spatial resolution (HR). Then the fusion images can be calculated with constructed dictionaries and sharing coefficient. Finally, the residual produced by sparse representation is interpolated as compensation. Compared with four methods in four evaluation indexes, SPCA method gives competitive or even better results on LandSat8 and QuickBird.


Real-time monitoring is necessary for saving endangered wildlife. The camera-trapping technology is used to monitor wild animals like tigers, lions, bears etc. in forests. Due to changes in the forest echo system and the expansion of human civilization near the forest, tigers often enter the villages. As a consequence, the Tiger-Human conflict occurs more frequently. Typically, cloud computing technologies are used for storing and processing the image data generated from trap cameras. A wildlife monitoring system is a time-sensitive application, and processing and decision-making using cloud computing are relatively slow. Timeliness and quick response are essential for these types of applications. Highlighting this issue, this article focuses on the design and development of a fog-assisted tiger alarming framework that detects tigers in the corridor. The application also delivers systematic alerts to the villagers. Therefore, the conflict between humans and tigers will reduce. For comparison, we have deployed the same model in a cloud computing environment. The proposed framework is simulated in the iFogSim simulator. The outcome exhibits that the proposed fog-based model successfully reduces latency and network usage compared to the traditional cloud-based model. The comparative analysis also indicates a significant improvement in the execution time over the cloud system.


The invention discloses a method for synthesizing dimethyl oxalate and by-producing dimethyl carbonate, which adopts industrial grade CO and O2 with a purity of more than 98 percent and industrial grade methanol with a purity higher than 99.5 percent as raw materials and NO as auxiliary material, so as to prepare dimethyl oxalate and by-produce dimethyl carbonate through nitrosation, oxidative carbonylation, and extraction and rectification circulation. The invention comprises four circulation loops: an NO/CH3ONO circulation loop consisting of an oxidative carbonylation reactor and a nitrosation reactor, a methanol circulation loop 1 consisting of a nitrosation reactor and a water separation tower, a water/ steam circulation loop consisting of an oxidative carbonylation reactor and a nitrosation reactor, and a methanol circulation loop consisting of a methanol cleaning tower and a methanol circulation tower. The invention provides a method used for synthesizing dimethyl oxalate and by-producing dimethyl carbonate from the CO with industrialized development value.


ABSTRACT Nuclear shape and size are cell-type specific. Change in nuclear shape is seen during cell division, development and pathology. The nucleus of Saccharomyces cerevisiae is spherical in interphase and becomes dumbbell shaped during mitotic division to facilitate the transfer of one nucleus to the daughter cell. Because yeast cells undergo closed mitosis, the nuclear envelope remains intact throughout the cell cycle. The pathways that regulate nuclear shape are not well characterized. The nucleus is organized into various subcompartments, with the nucleolus being the most prominent. We have conducted a candidate-based genetic screen for nuclear shape abnormalities in S. cerevisiae to ask whether the nucleolus influences nuclear shape. We find that increasing nucleolar volume triggers a non-isometric nuclear envelope expansion resulting in an abnormal nuclear envelope shape. We further show that the tethering of rDNA to the nuclear envelope is required for the appearance of these extensions. Summary: Nucleolar size influences nuclear shape in yeast. Nucleolar expansion triggers phospholipid biosynthesis leading to nuclear envelope shape abnormalities.


THE GOVERNMENTAL PROBLEM IT may seem unnecessary to go back to the essentials of United States government in order to set the stage properly for an examination of criminal prosecution in the United States. But much of our inefficiency in administering the criminal law comes from the successive layers of government which are superimposed upon the citizens of our country. And many of our present day troubles in matters of personnel seem to have their source in the retention of the " ideals " of local democracy fostered by political leaders of a century ago. The preservation of a complex system of local selfgovernment with an elected officialdom has made the thorough reform of our methods of criminal prosecution impossible. European students of law enforcement are inclined to condemn conditions in the United States without making allowances for the peculiar difficulties which our citizens face. The thesis of this paper is simple: certain conditions, peculiar to the United States, especially the problems of a federated government, should be considered before any attempt is made to evaluate law enforcement in our country. 1. The National Layer.-Our Federal government administers criminal justice as it relates to crimes against the United States. It must be remembered that the powers of the Federal government" are made up of concessions from the several states. Whatever is not expressly given to the


Research background: Globalization processes bring many advantages and disadvantages within the economic, political, social as well as ecological environment. The economic advantages come mainly from the possibility of finding cheaper production inputs, which results in better competitiveness of companies and the supply of goods at lower prices.
Purpose of the article: In order to obtain a comprehensive view of the company's development, it is appropriate to use a model of six levels of company development, which allows for a good structuring of general and specific conditions of company development.
Methods: The paper deals with the analysis of individual levels of business development, which are described in more detail in the introduction, which was carried out through a questionnaire, observation, personal interviews, etc. It also contains suggestions for improvements where industrial engineering methods are used. The benefits of the following study may include the analysis of individual levels in practice, the design of the use of a six-level model at various levels of business development, increasing the abilities and skills of individual operators by introducing a substitution matrix that will include individual operators in the cells.
Findings & Value added: Another benefit is an increase in motivation for employees, which will affect the work performance and quality of finished products using a new incentive system with various rewards. The information obtained about customers through the implementation of the CRM system provides all the information from the beginning of communication with the customers themselves and improved the clarity of the activities of individual employees.


This paper uses the MESANGE model to estimate the strength of automatic stabilizers. Following a demand shock, the
attenuation of GDP volatility is moderate (10%) in the first year, but greater (20%) in the second year. The items with the
greatest stabilizing influence are VAT, taxes on production, and unemployment benefits. The stabilizing effect also
depends on the dynamic profile of the disturbance, and can vary by a factor of two depending on the profile. For supply
shocks, the results depend on the implications for potential GDP. Public finances contribute to adjustment after a positive
productivity shift, but appear to have increased GDPvolatility by 10 percent due to oil-price variations between 1990 and
2000.


Previous preemptive real-time (m,k)-firm schedulers all try a best effort policy to dispatch k-m executions when m out of k consecutive task executions have met their deadlines. These additional executions can only bring value to the system if no firm deadline is missed. In this paper we present a framework whereby an on-line feasibility test is carried out on these k-m executions before dispatching them. With our scheme, all dispatched tasks are guaranteed to meet their deadlines.


Abstract Previous molecular phylogenetic studies have focused on either the relationship between isopteran families or among species within a given genus, but there are presently few studies focusing on individual families and no known molecular studies for Rhinotermitidae. We examined 38 rhinotermitid species representing 10 genera, relative to representatives of four other isopteran families. Sequencing of a 667-base pair region of the mitochondrial DNA cytochrome oxidase II gene revealed 343 polymorphic sites within the family. Tajima-Nei genetic distances ranged from 11 to 23% among rhinotermitid genera. Maximum parsimony and maximum likelihood analysis of DNA sequences support existing hypotheses that Mastotermitidae is the basal lineage among extant termites, and the family Rhinotermitidae is polyphyletic given the current familial status of Serritermitidae. DNA sequence data suggest that Serritermitidae should be relegated to the subfamily Serritermitinae, as proposed by Emerson in 1965.


The Tuzo Wilson Volcanic Field (TWVF) consists of Quaternary alkaline volcanics erupted at the complex, diffuse triple junction between the Explorer, Pacific, and North American plates. It occurs in a region of distributed strain that lies between right-lateral, strike-slip faulting at the Queen Charlotte fault, seafloor spreading at the Explorer Ridge, and subduction at the Cascadia subduction zone. The TWVF is contained within a poorly defined graben structure and consists of two 500- to 700-m-high composite seamount volcanoes surrounded by numerous smaller vents, with a total edifice volume of about 12 km3. The erupted volcanics are large ion lithophile elements (LILE) and light rare earth element (LREE) enriched alkali basalts, hawaiites, mugearites, and benmoreiites. These volcanics also differ from mid-ocean ridge basalts by lacking Fe enrichment and Al depletion trends and by having low relative Fe, Sc, and Cr and high relative Al for a given MgO content, reflecting significant high-pressure pyroxene fractionation. They are petrologically similar to other alkaline volcanics found capping near-ridge seamounts in the east Pacific. Petrogenetic modeling combined with analysis of Sr, Nd, and Pb isotopic data shows that TWVF volcanism is ephemeral in nature and that the TWVF lavas were derived by small amounts of melting (≤3%) of an amphibole-bearing, LREE- and LILE-enriched heterogenous mantle similar to that underlying the adjacent Explorer spreading ridge. The new volcanological, petrological, and geochemical data presented constrain both the petrogenetic origin of TWVF lavas and the tectonic processes occurring in the triple junction region. Current wisdom states that the TWVF represents either a site of seafloor spreading or a hotspot/mantle plume. Our new data are incompatible with these models and instead are consistent with other geophysical data in suggesting that the TWVF represents minor volcanism associated with pull-apart structures developing between parallel strike-slip faults in a region of distributed strain. In short, the TWVF represents "leaky transform" volcanism in an oceanic setting.


In this study ,increasing the aflatoxin B1 more than 30 ug/L in the medium decreased the count of the lexamined strains especially Lactobacillus casido which decreased from 9.4x10 to 8.4x10 cell/ml at concentration 225ug/L. Although the amount of bound toxin increased from 25.2 to 57.75 ug/L , the percent of bounding decreased from 84% to 77%. Almost the same trend was observed in case of Lactobacillus acidophilus and Bifidobacterium .On other hand increasing the bacterial count from 10 to 10 cell/ml increased the percentage of binding toxin from 55,32, and 54 to 81,60 and 90% for Lactobacillus acidophilus and Bifidobacterium Bifidum respectively. The percentage of. Binding remaining almost the same by increasing the incubation time more than 30 min . At initial pH 4 and 7 the count of the tested bacteria slightly decreased after 3 hours of incubation while at initial pH 9 decreased to about 5 after the incubation time the results indicated that the initial pH between 2 to 4 slightly affected the bacterial count and the pH of the media after 24 hours of incubation while pH 5 or more till 9 sharply increased the count of the tested lactic acid bacteria while the final pH decreased to about 4 after the end of the incubation time . The results also revealed the increasing the initial pH more than 5 aِffected the percentage of binding aflatoxin B1 while the percentage of media decreased at pH less than 5. H. A. HUSSIEN / J. Rad. Res. Appl. Sci., Vol. 1, No. 2 (2008) 350


What lessons can we draw from the refuse-to-energy industry's past. And how can these be applied toward further development. Two distinct periods of development are examined in this article to help one industry's progress and understand what lies ahead. During the mid- to late-Seventies, a great deal of activity took place, resulting in many false starts. These years were marked by early design and development failures caused by consultants and vendors who couldn't necessarily deliver all they promised. The second period, from 1982 - 1987, was critical in terms of both acquiring technical expertise and implementing successful projects. Today, the industry has reached a certain level of maturity resulting, in part, from the development of sophisticated environmental controls and the integration of these controls with a totally automated combustion process. Within the next 10 years, substantial progress will be made in treating products from the ash residue and further improving the design and operation of air quality controls.


A national survey to obtain information about the Quality Assurance (QA) procedures and methods being followed at Indian radiotherapy centers for intensity modulated radiation therapy (IMRT) was conducted. A questionnaire containing parameters relevant to IMRT QA was evolved to collect the information pertaining to the QA of IMRT delivery system, QA of IMRT treatment planning system, and patient specific IMRT QA. The questionnaire was circulated to 40 hospitals in the country and responses of 31 centers were received. Survey results showed that 71% centers are having adequate machine specifi c IMRT QA programme, 19% centers have inadequate machine specific IMRT QA programme and 9% centers have irrelevant machine specific IMRT QA programme. No specific answer for question of QA tests of TPS specific to IMRT were received from the user. Almost all the centers have programme of setup verification of the patient by means of EPID/DRR/OBI. However, 91% of centers could not provide any information about the QA methodology of the devices used for setup verification. For patient specific dosimetric QA, almost all the hospitals have the program of pre-treatment dose verification using calibrated ionization chambers of sensitive volumes in the range of 0.01 to 0.65 cc. Dosimetric verification is performed by combining dose from all gantry angles to a single gantry angle. Two dimensional (2D) dosimetry systems such as radiographic and radiochromic films, 2D array of ionization chambers/ semiconductor diodes and EPID are also used in patient specific dosimetry verifications. Majority of the centers (about 48%) accept the plan with 3% dose difference and 3 mm dose to distance agreement criteria with gamma index less than unity. However, a number of other acceptance criteria specific to institution and tumor site are being also followed. This survey reveals that a variety of IMRT QA program is being followed at the Indian hospitals. This study has brought into focus the need to evolve a national protocol for IMRT QA so that treatment outcomes of all the IMRT centers of country can be compared.


Loess is an important soil type that is widespread in the Loess Plateau of northwest China. However, mining exploitation, beneficiation, and metallurgy have led to inorganic contamination of soils that threatens the health of residents. The regular absorption peak shift of near-infrared (NIR) spectra in loessal soils represents a new method of soil environmental assessment based on field reflectance spectroscopy and hyperspectral remote sensing. Specifically, the NIR features of loessal soil will shift in response to changes in the soil composition and microstructure induced by heavy metal pollution. This study collected 27 samples from notable regions in the study area. Mid-infrared (MIR) spectral analysis, NIR spectral analysis, modified seven-step Tessier sequential extraction, and X-ray diffraction were used to analyze the band shift phenomenon of MIR and NIR features. The alignment of NIR bands was determined via the correlation between NIR and MIR bands associated with the vibration variations of the hydroxyl group. The correlations established by NIR band positions and exchangeable Cd cations were also analyzed. The results were then discussed according to the mineralogical characteristics of the heavy metal cations adsorbed on the surface and interlayer sites of clay minerals. These results can be used as a reference for the application of NIR technology to detecting heavy metal contamination in the soil of mining regions.


Contact: Decio Hall, Box "D" University of Notre Dame, Notre Dame, Indiana 46556. Tel. 574-631-5681 http://www.nd.edu/~apsacp Michael Coppedge University of Notre Dame email@example.com John S. Saden Professor of Political Science at Yale University, Director of the Yale Program on Democracy, and current Chair of the Department of Political Science. Her research interests include democratic theory and how democracy functions in developing societies, with a regional focus on Latin America.


Summary Passive seismic interferometry is a relatively new image method and has been applied for many engineering and exploration geophysical investigations. It includes two major methods which are cross-correlation and autocorrelation. The cross-correlation of ambient noise record between two receivers will generate a virtual shot at one receiver location. Autocorrelation of a passive seismic data trace can be considered to yield a conventional zero-offset trace. The autocorrelation of all traces in the passive seismic gather can be considered as a zero-offset section. Both methods could be used in the passive seismic data imaging. In this study, we apply both methods to a passive data set acquired at a well-known geological storage site, Ketzin. We processed the passive data sets by autocorrelation and cross-correlation. We compared the stack sections obtain by autocorrelation, processing of shot gathers got by cross-correlation and active survey. The autocorrelation sections surprisingly have a very good agreement with the active stacked section. The stack sections obtain by processing virtual shot gathers obtained by cross-correlation show some similar features compared with the active stacked section but much worse than the autocorrelation section.


The protection of plant genetic resources aims at growing and maintenance of live plants out of their natural environment, in the form of whole plants, seeds, pollen, tissues or cell cultures. Botanical gardens are very important for maintaining species and genetic diversity. They play an important role in raising public awareness of biodiversity conservation and plant genetic resources. The Botanical garden of the Institute of Plant Genetic Resources (IPGR) in Sadovo was established in 2002 under the Plant genetic resources program in the frameowrk of the National Strategy for Biodiversity Conservation (1994) and National Action Plan (2000). It contributes to the conservation and wise use of plant genetic resources. The purpose of this article is to describe and promote some of the rare and endemic species grown in the Botanical garden of IPGR - Sadovo.


Methane is an important greenhouse gas with high warming potential,most of methane emit from various wetlands.Some studies on methane emission in wetlands were done,however,few studies were reported in China,especially on tidal marsh.Production of methane is the basis of methane emission,and is also the first step of methane emission influencing greatly the emission process.Hence,research on the fields is necessary. The Minjiang River Estuary wetland was one of the tidal wetlands,which is situated on the southeast seashore of China influenced by tide,the concentrations of soil water content,salinity and electron acceptors were changed,and the effects of variation of soil physiochemical properties on methane production were unknown. Phragmites australis was one of the main species in Minjiang River Estuary wetland,distributed on the intertidal belt,so our study took Phragmites australis marsh which is typical and representative as the study areas. The methane production potential from the Phragmites australis marsh soil of the Minjing River Estuary after the import of electron acceptors and salt was determined using an anaerobic incubation technique.The range of methane production potential in different soil layers was 0.0202-0.0871μg·g-1·d-1,the average value was 0.0378 μg·g-1·d-1,and the highest methane production potential occurred in the surface soil,differing significantly from other soil depths(P0.05).Methane production potential was inhibited by electron receptors import.When the concentrations of three kinds of electron acceptors increased from 4 to 12 mmol/L,methane production potential all dropped gradually.The methane production potential after adding nitrate and ferric was significantly different from that of controlling soils(P0.05),but there was no significant difference when adding sulfate.There was no significant difference when the different concentration levels of the three types 08 electron receptors were applied(P0.05).The inhibited effect of the three electron receptors on methane production potential was nitrateferricsulfate;and methane production potential was partly inhibited by salt.The methane production potential dropped when the concentration increased from 4 to 12 mmol/L.The difference was not significant between the methane production potential after adding salt and controlling soil,and also the three concentration levels salt import(P0.05).


We propose Multidimensional Random Slice-based Sparse Fourier Transform (MARS-SFT), a sparse Fourier transform for multidimensional, frequency-domain sparse signals, inspired by the idea of the Fourier projection-slice theorem. MARS-SFT identifies frequencies by operating on one-dimensional slices of the discrete-time domain data, taken along specially designed lines; these lines are parametrized by slopes that are randomly generated from a set at runtime. The discrete Fourier transforms (DFTs) of data slices represent DFT projections onto the lines along which the slices were taken. On designing the line lengths and slopes so that they allow for orthogonal and uniform projections of the sparse frequencies, frequency collisions are avoided with high probability, and the multidimensional frequencies can be recovered from their projections with low sample and computational complexity. We show analytically that the large number of degrees of freedom of frequency projections allows for the recovery of less sparse signals. Although the theoretical results are obtained for uniformly distributed frequencies, empirical evidence suggests that MARS-SFT is also effective in recovering clustered frequencies. We also propose an extension of MARS-SFT to address noisy signals that contain off-grid frequencies and demonstrate its performance in digital beamforming automotive radar signal processing. In that context, the robust MARS-SFT is used to identify range, velocity, and angular parameters of targets with low sample and computational complexity.


Context: The V600E mutation accounts for the vast majority of thyroid carcinoma-associated BRAF mutations. Objective: The aim was to study the effects of the two BRAF V600E ATP-competitive kinase inhibitors, PLX4032 and PLX4720, in thyroid carcinoma cell lines. Experimental Design: We examined the activity of PLX4032 and PLX4720 in thyroid carcinoma cell lines harboring BRAF V600E (8505C, BCPAP, SW1736, BHT101), NRAS Q61R (HTH7), KRAS G12R (CAL62), HRAS G13R (C643), or RET/PTC1 (TPC-1) oncogenes. Normal thyrocytes (PC Cl 3) were used as control. Results: Both compounds inhibited the proliferation of BRAF mutant cell lines, but not normal thyrocytes, with a half maximal effective concentration (EC50) ranging from 78-113 nM for PLX4720 and from 29-97 nM for PLX4032. Doses equal to or higher than 500 nM were required to achieve a similar effect in BRAF wild-type cancer cells. Phosphorylation of ERK 1/2 and MAPK kinase (MEK) 1/2 decreased upon PLX4032 and PLX4720 treatment in BRAF mutant thyroid carcinoma cells but not in normal thyroid cells or in cell lines harboring mutations of RAS or RET/PTC1 rearrangements. PLX4032 and PLX4720 treatment induced a G1 block and altered expression of genes involved in the control of G1-S cell-cycle transition. 8505C cell tumor xenografts were smaller in nude mice treated with PLX4032 than in control mice. This inhibition was associated with reduction of phospho-ERK and phospho-MEK levels. Conclusions: This study provides additional evidence of the promising nature of mutant BRAF as a molecular target for thyroid carcinoma cells. The Glucocorticoid-Induced Leucine Zipper Gene (GILZ) Expression Decreases after Successful Treatment of Patients with Endogenous Cushing's Syndrome and May Play a Role in Glucocorticoid-Induced Osteoporosis Tove Lekva, Jens Bollerslev, Cybéle Kristo, Ole Krisoffer Olstad, Thor Ueland, and Rune Jemtland (J Clin Endocrinol Metab, published October 29, 2009, 10.1210/jc.2009-0595) ABSTRACT Context: Glucocorticoid-induced bone loss is a serious complication in patients with endogenous Cushing's syndrome. However, the mechanism(s) by which excess glucocorticoids influence bone metabolism is not completely understood. Objective: The aim of the study was to investigate the functional role of glucocorticoid-induced leucine zipper (GILZ) in bone remodeling with special focus on glucocorticoid-induced osteoporosis (GIO). Patients: Nine patients with endogenous Cushing's syndrome participated in the study. Research Design and Methods: We analyzed bone biopsies from Cushing's patients before and after treatment to screen for expressional candidate genes with putative roles in GIO. Microarray analysis combined with real-time RT-PCR revealed that the gene encoding GILZ ranked among the topmost regulated genes and was selected for functional characterization in vitro. Results: GILZ mRNA was expressed by human fetal osteoblasts (hFOB), human mesenchymal stem cells (hMSC), osteoblasts differentiated from hMSC, and osteoclasts. GILZ was increased by dexamethasone in a timeand dose-dependent manner in hFOB. Inhibition of GILZ in hFOB cells by small interfering RNA decreased typical osteoblast-related genes, suggesting a physiological role in promoting osteoblast maturation. Our data further support a functional role for GILZ in normal bone remodeling by modulating expression of TNF-(ligand) receptor superfamily/osteoprotegerin in favor of increased ratio in hFOB. Finally, osteoclasts exposed to conditioned media from GILZ-silenced hFOB indicated effects on osteoclast activity. Conclusion: Taken together, these results implicate the transcription factor GILZ in the pathophysiology of GIO by regulating osteoblast maturation and bone turnover. 932 Abstracts Translational Highlights from JCEM Endocrine Reviews, December 2009, 30(7):926–934Context: Glucocorticoid-induced bone loss is a serious complication in patients with endogenous Cushing's syndrome. However, the mechanism(s) by which excess glucocorticoids influence bone metabolism is not completely understood. Objective: The aim of the study was to investigate the functional role of glucocorticoid-induced leucine zipper (GILZ) in bone remodeling with special focus on glucocorticoid-induced osteoporosis (GIO). Patients: Nine patients with endogenous Cushing's syndrome participated in the study. Research Design and Methods: We analyzed bone biopsies from Cushing's patients before and after treatment to screen for expressional candidate genes with putative roles in GIO. Microarray analysis combined with real-time RT-PCR revealed that the gene encoding GILZ ranked among the topmost regulated genes and was selected for functional characterization in vitro. Results: GILZ mRNA was expressed by human fetal osteoblasts (hFOB), human mesenchymal stem cells (hMSC), osteoblasts differentiated from hMSC, and osteoclasts. GILZ was increased by dexamethasone in a timeand dose-dependent manner in hFOB. Inhibition of GILZ in hFOB cells by small interfering RNA decreased typical osteoblast-related genes, suggesting a physiological role in promoting osteoblast maturation. Our data further support a functional role for GILZ in normal bone remodeling by modulating expression of TNF-(ligand) receptor superfamily/osteoprotegerin in favor of increased ratio in hFOB. Finally, osteoclasts exposed to conditioned media from GILZ-silenced hFOB indicated effects on osteoclast activity. Conclusion: Taken together, these results implicate the transcription factor GILZ in the pathophysiology of GIO by regulating osteoblast maturation and bone turnover. 932 Abstracts Translational Highlights from JCEM Endocrine Reviews, December 2009, 30(7):926–934 Downloaded from https://academic.oup.com/edrv/article-abstract/30/7/932/2355128 by guest on 07 March 2018


Investigated is the influence of temperature on oxygen consumption in the Baikal grayling, Thymallus arcticus baicalensis, at rest and at different speeds of swimming. The grayling, a stenothermal species, living at comparatively low temperatures, is adapted to active swimming at high speeds.


Chloroplast transformation technology has emerged as an alternative platform offering many advantages over nuclear transformation. SAG1 is the main surface antigen of the intracellular parasite Toxoplasma gondii and a promising candidate to produce an anti-T. gondii vaccine. The aim of this study was to investigate the expression of SAG1 using chloroplast transformation technology in tobacco plants. In order to improve expression in transplastomic plants, we also expressed the 90-kDa heat shock protein of Leishmania infantum (LiHsp83) as a carrier for the SAG1 antigen. SAG1 protein accumulation in transplastomic plants was approximately 0.1-0.2 μg per gram of fresh weight (FW). Fusion of SAG1 to LiHsp83 significantly increased the level of SAG1 accumulation in tobacco chloroplasts (by up to 500-fold). We also evaluated the functionality of the chLiHsp83-SAG1. Three human seropositive samples reacted with SAG1 expressed in transplastomic chLiHsp83-SAG1 plants. Oral immunization with chLiHsp83-SAG1 elicited a significant reduction of the cyst burden that correlated with an increase of SAG1-specific antibodies. We propose the fusion of foreign proteins to LiHsp83 as a novel strategy to increase the expression level of the recombinant proteins using chloroplast transformation technology, thus addressing one of the current challenges for this approach in antigen protein production.


The main purpos 巴 ofthis paper is Lo provide an evaluation m 巴 thodassociat 巴 dwith th 巴 us 巴 of statistical in[er 巴 nc 巴 approachLo policy rul 巴 andiLs simulation analysis. Namely , in stabilization policy probl 巴 msdon 巴 inth 巴 past , stochasLic judg 巴 mcntis not d 巴 velop 巴 din the adjustm 巴 ntbetw 巴巴 ntarget and instrum 巴 ntv 巴 ctors.In addition to the newly design analysis , W 巴 criticallyr 巴 consid 巴 redmethods and r 巴 sultsof quantitativ 巴 stabilizationpolicy analysis in Lhe pr 巴 viousworks of combin 巴 dconLrol th 巴 oryand macro 巴 conomicpolicy probl 巴 ms. Bc[or 巴 doingLh 巴 abovediscussions , Lhis pap 巴 ralso pres 巴 ntsbri 巴f1 y 巴 xpositoryimplication and a conliguration o[ sLructural analysis and policy d 巴 sign. Furthermore , w 巴 introduc 巴 d th 巴 scbematicdiagram for discussing most aspects of econom 巴 Lricmodcls investigating and invesLigat 巴 dsom 巴 evaluationsof dynamic stabilization problems in lin 巴 arsLochasLic mod 巴 Is d 巴 V 巴 lop 巴 din th 巴巴 conometricand control 巴 ngm 巴巴 ringlit 巴 ratures.


Synchronous condenser is an important reactive resource of power system, the operation of which is significant. Its model has always been a major concern to researchers, because accurate and reasonable synchronous condenser parameter is the basis of analysis and calculation of system dynamic behavior. With the increasing of the safety and stability of power grid, it is more imperative to obtain modeling and parameter identification method. In this paper, generator and excitation system model and parameter identification of synchronous condenser are studied and summarized, in order to obtain its equivalent model which can in accord with or be close to practical operation state.


The main purpose of the article is to identify the key competencies of the management staff and employees of meetings industry enterprises during the COVID-19 pandemic, which made it possible to secure the functioning of these entities during the crisis. The results of this survey, conducted in 2020 and 2021 among employees of this industry in three countries—Poland, Ireland, and Hungary, are the basis for a discussion on the competency profiles and competency gaps of employees in the meetings industry. Further research in this area of MICE competencies and the preparation of recommendation packages are necessary in order to prepare the industries for future possible crises based on the knowledge gained during the COVID-19 pandemic.


Wave–particle interactions play important roles in local acceleration and pitch angle scattering loss of charged particle dynamics in astrophysics and space physics, and energy transfer between plasma waves and particles is a key problem in plasma physics. Using full relativistic test particle simulations, we quantitatively evaluate the magnetosonic wave-driven acceleration of Earth's ring current protons both inside and outside the plasmapause at L = 4.5. Analysis of resonance conditions indicates that the broadband magnetosonic waves can affect protons by multiple harmonic cyclotron resonances. With a representative amplitude ∼200 pT, magnetosonic waves can produce energy diffusion coefficients, obtained from test particle simulations, at rates of ∼10−4 s−1 for protons ∼1–3 keV inside the plasmapause and ∼3–30 keV outside the plasmapause, both at equatorial pitch angles ∼75°–90°. Compared with the quasilinear theory calculations, the test particle diffusion coefficients exhibit a difference due to the nonresonant transit time effect outside the plasmapause. Subsequent 2D Fokker–Planck simulations indicate that on a timescale of ∼2 days, magnetosonic waves can effectively enhance the phase space density of the ring current protons ∼10 keV inside the plasmapause and ∼100 keV outside the plasmapause at equatorial pitch angles ∼60°–90°, thereby leading to the evolvement of the ring current proton distribution from a Kappa-type to a 90°-peaked profile. Our results demonstrate that the local acceleration of the ring current protons by magnetosonic waves is an important process of energy transfer between different populations of magnetospheric protons and hence contributes to the dynamic evolution of Earth's ring current.


America's Middle East policy has been a haphazard blend of hard-headed realism, idealism and dispensationalist theology. The result has not served US interests well.


It is well-known that a linear regression among the levels of independent highly persistent processes yields high values of the corresponding coefficient of determination along with divergent I-ratios and low values of the Durbin-Watson statistic. In fact, such a behaviour of the customary OLS statistics has become a sort of definition of the so-called spurious regressions in econometrics. In this paper, however, we show how these spurious stylized facts also arise among nonstationary (fractionally) cointegrated processes.


In a world of outstanding diversity, perhaps one unifying theme is the desire to solve societal issues through technology. The momentum for success hinges on deploying these solutions in a market-appropriate way.


The paper expounds the purpose and the importance of the test for power characteristics of infrared lamp,and analyzes the dynamic test results.The steady state power-electric current equation by test data fitting provides the basis to design controlling project of infrared simulator.


In this paper,the functions in motor design are repeatedly utilized with the dynamic link library (DLL) independent of programming environment.The repeatedly developing question of the same code under another programming environment is solved by means of DLL in motor design.


Having recently completed a placement as a student nurse in a busy teaching hospital, I spent several occasions in triage with my mentor.


In recent years, direct current (DC) power supply loads have become more prevalent in industrial and commercial applications. As a result, an ac/dc converting system will be placed at the system's front end to convert alternating current mains into direct current sources for system operation. Load-end characteristics of the system will increase the phase shift between the voltage and current of the input AC power source. This has a detrimental impact on the system's power quality indicators and causes instability. In an ac/dc converter that needs power quality improvement, a power factor corrector converter is required between the uncontrolled rectifier and the load. Different converter topologies have been investigated and compared in this paper. The self-PFC features of various converter topologies are examined.


Abstract Different granulometric fractions of surface sediment samples and dissected sediment cores taken from Matanzas Bay and from three inflowing rivers were investigated for the content of metals (Al, Cd, Co, Cr, Cu, Fe, Hg, Mn, Ni, Pb, Zn) and organic matter. the data on 'total' and easily extractable metal fractions were normalized and statistically treated with the aim of finding procedures applicable for assessment of the sources and levels of contamination. the results show clearly that the investigated area is not much contaminated with respect to those determinands. However, sewage effluents, urban runoff and industrial discharges from Matanzas City draining to the bay via two rivers cause elevated heavy metal levels in sediments of the rivers and of the adjacent coastal areas. in addition, a tannery discharge was revealed as a contamination 'hot spot' for chromium.


With the curriculum Lpfo98, and its revised version 2010, the demands for evaluation of the quality of the preschool have been emphasized. Accordingly, the activities need to be systematically docu ...


linear programming An optimization problem for designing of a non-uniformly spaced, linear phase FIR filter with coefficients consisting of minimum number of signed-power-of-two terms is formulated. The aim of this paper is first to reduce the region that contains the optimal solution in order to decrease the computation time and, then FIR filters are designed using mixed integer linear programming (MILP). In this paper we minimize the number of signed-power-of-two-terms per coefficients for defined range of stopband ripple and fixed passband ripple, subject to filter specification, filter order and number of coefficient bits. We optimize both coefficients representation and stopband ripple. In our method all possible coefficient values for given stopband ripple are calculated and compared and thus the one containing a minimum number of terms is selected. It is shown that our optimization procedure compares very favorably with other known methods.


Objective: Banding of the pulmonary artery might be required to prevent pulmonary vascular damage in patients with increased pulmonary artery flow and to retrain the left ventricle in preparation for an arterial switch operation in patients with congenitally corrected transposition of the great arteries. Readjustment of the pulmonary artery band might be required in the postoperative period. In this study we aimed to test the feasibility of a novel device for bidirectionally adjustable pulmonary artery constriction.


Far-ultraviolet spectra have been obtained of the eclipsing, hot subdwarf binary, BE UMa, with phase coverage in the 2.3-day orbital period concentrated near minimum light. No clearly phase-related spectral changes were found, but the UV continuum appeared to be in a highly variable state, with changes of a factor of two occurring on a time scale of hours. The hot star in this system may be one of the few known PG 1159-035 variables, which show nonradial pulsations. If so, this is the first such star known in a binary system and thus should be important for determining the physical properties of these stars.


The widespread use of thermal barrier coatings (TBC) in gas turbines stresses the importance of accurate life prediction models for TBCs. During service, the TBC may fail due to thermal fatigue or through the formation of thermally grown oxides (TGOs). The current paper presents a Thermo-Calc/Dictra-based approach to life prediction of isothermally oxidised atmospheric plasma sprayed (APS) TBCs. The β-phase depletion of the coating was predicted and compared to life prediction criteria based on TGO thickness and Al content in the coating. All tried life models underestimated the life of the coating where the β-depletion-based model was the most conservative.


New graft copolymers were synthesized by grafting methyl acrylate onto cutch, a vegetable tanning agent, in acetic acid medium with hydrogen peroxide as the initiator. The graft copolymers were characterized by infrared spectroscopy and thermogravimetric analysis. The dependence of the percentage of grafting, monomer conversion, efficiency of grafting and rate of grafting on the concentrations of initiator, acetic acid, and cutch were investigated. The optimum experimental conditions for grafting were obtained. A probable mechanism of grafting was also proposed.


This article describes an innovative teaching aid that is cost and time efficient as well as effective with students in a nursing program. A diagram with specific measurements and a supply list is included.


This article provides an economic interpretation of some alternative policies that could replace or augment the expiring ethanol blender's credit. Several alternatives have been proposed, which include eliminating the blender's credit and maintaining the mandate, implementing a producer's income or investment tax credit or creating a variable blender's credit. Eliminating the blender's credit only has market impacts when the mandate is not binding. An ethanol producer's income tax credit has market impacts that are indistinguishable from the current blender's credit. A producer's investment tax credit has the potential to reduce the risk of entry for biofuel products. A variable ethanol blender's tax credit can achieve significant cost savings over a fixed blender's tax credit while achieving the same objectives. These cost savings can then be used to reduce program costs to taxpayers or be used to achieve additional objectives.


The Kozai mechanism for exponentially exciting eccentricity of a Keplerian orbit by a distant perturber is extended to a general perturbing potential. In particular, the case of an axisymmetric potential is solved analytically. The analysis is applied to orbits around an oblate central object with a distant perturber. If the equatorial plane of the central object is aligned with the orbit of the distant perturber (axisymmetric potential), a single instability zone, in which eccentricity grows exponentially, is found between two critical inclinations; if misaligned (non-axisymmetric potential), a rich set of critical inclinations separating stable and unstable zones is obtained (Vashkoviak 1974). The analysis is also applied to a general quadratic potential. Similarly, for non-axisymmetric cases, multiple stability and instability zones are obtained. Here eccentricity can reach very high values in the instability zones even when the potential's deviation from axisymmetry is small.


Abstract— The preparation of analogues of fentanyl with N‐phenyl replaced with a heterocyclic aromatic ring, and with N‐alkyl/arylalkyl N‐acyl substituents is reported. Only those compounds carrying an N‐phenylethyl substituent were active in the rat tail‐withdrawal test. Fentanyl (1) is the prototype of the 4‐anilido‐piperidine class of opioid analgesics (Casy & Parfitt 1986). Several recent publications (Casy & Huckstep 1988; Bagley et al 1989) on this series have dealt with heterocyclic and aromatic modifications of the fentanyl molecule. Although the antinociceptive potency of most novel derivatives was greater than that of morphine, they had reduced activity when compared with fentanyl itself. To acquire further information on the structure‐reactivity relationships of the series, new heteroaryl derivatives have been prepared and tested for antinociceptive activity.


Randomly oriented short fiber mat reinforced polyester composite laminates immersed in natural seawater for various periods were tested in static and cyclic fatigue loading under three-point bending conditions. Water absorption increased the weight of the specimen while the extraction of soluble compounds induces a weak weight loss. Wohler curves carried out from repetitive fatigue tests were drawn for the different periods of immersion time. These curves, which are characterized by an important and a significant scatter in their lifetime, were modeled by straight lines. These glass-polyester laminates deteriorate in fatigue tests at a constant rate by cycle decade. This rate increases with increasing immersion time in seawater at a constant speed. A comparison between different mathematical models of endurance curves shows that Wohler's equation gives a good representation of the average part of the curve.


We study consumption behavior, retirement decisions, and endogenous growth within a dynamic equilibrium when individuals have present-biased preferences. Compared to individual with exponential preferences, individual with hyperbolic preferences will choose to retire early for present-biased preferences but to delay retirement for the initial time preference rate. We extend the benchmark equilibrium model to age-dependent survival law and solve numerically the equilibrium effects. It shows that, at the same age, the consumption-capital ratio may have slightly positive effect on increasing life expectancy before retirement but has a significantly positive effect on it after retirement.


Locus of control is an indicator that affects job satisfaction and performance. The aspects that are assessed on the performance of the Audit Board auditors cannot be separated from the locus of control, leadership style, and job satisfaction. All these aspects are assessed proportionally by giving a more dominant weight to work performance without neglecting the aspects of work behavior. The selection of Audit Board Representative of East Java Province auditors cannot be separated from the locus of control and leadership style to create auditor performance which is mediated by job satisfaction in East Java, both because of internal and external factors. The purpose of this study is to analyze the effect of locus of control on job satisfaction of auditors at Audit Board Representatives of East Java Province, analyze the effect of job satisfaction on auditor performance, analyze the effect of locus of control on auditor performance, analyze the effect of leadership style on auditor performance, analyze the effect of job satisfaction mediates locus of control on auditor performance and analyzes job satisfaction mediates leadership style on auditor performance. This research used quantitative methods, while the sampling technique is based on purposive sampling and data processing use Partial Least Square (PLS) analysis with SMART PLS software. The results show that each variable affects each of the other variables. This research contributes to Audit Board Representatives of East Java Province paying close attention to the locus of control of auditors and considering work management mechanisms that harmonize the relationship between superiors and auditors. Therefore, further research requires more diverse and in-depth interviews, as well as various respondents.


This report is a compilation of facts and information that summarizes the present state of knowledge related to wave attack on the flood side of earthen levees. Particular emphasis was placed on the need for providing flood-side armoring (beyond the protection afforded by grass) for the New Orleans Hurricane & Storm Damage Risk Reduction System (HSDRRS). The report includes: (1) a summary of observations from Hurricane Katrina; (2) an extensive overview of large-scale experiments conducted in Europe, (3) a critical examination of proposed methodologies for predicting wave-induced damage on flood-side grass and bare-clay slopes, (4) an analysis of wave-induced erosion expected to occur on the flood side during hypothetical storms approximating the 100-yr and the 500-year events, (5) and a comprehensive list of conclusions and associated caveats. The erosion estimation methodologies for wave-induced erosion discussed in this report were applied to three sets of hypothetical extreme storm parameters to assess the need for providing wave erosion protection (i.e., armoring) on grass-covered and bare-clay flood-side slopes.


The spread spectrum technology has been used widely in fields such as military and civil communications because of its strong anti-interference, excellent secrecy.Thus it is very difficult to detect DSSS and estimate its parameters.Noticing that the direct sequence spread signal and Gaussian noise are different in cyclostation based on spectrum theory, so this paper presents a method that makes use of cyclic spectrum correlation technology to detect DSSS and estimate its parameters.The simulation results show that the algorithm is effective.


A comprehensive filter is developed to practically remove errors on position estimation derived from inertial measurement unit (IMU) raw signals. The comprehensive filter is applied to a bicep-curl exercise where the initial and end positions of the host (the forearm of the subject) is known. The comprehensive filter benefits from an explicit complementary filter, a zero-rate updating algorithm, Kalman filter, and a kinematic constraint. The sequence of two Kalman filters provides a significant reduction in the velocity and position drift.


Recently microelectromechanical systems (MEMS) devices have become an important technology that is used in many applications. We describe post-processing steps of CMOS technology to implement a MEMS structure suitable for RF systems. We describe CMOS-based monolithic MEMS structures suitable for realizing passive RF components operating at frequencies of up to 60 GHz. Examples of RF MEMS components - inductors, switches and tunable capacitors, and coplanar transmission lines - realized in this technology are given.


In wireless body area networks (WBANs) it is necessary to devise an energy-efficient MAC scheduling mechanism which is capable of meeting strict QoS requirements. In this paper, special characteristics of WBAN channels, namely, the slow fading, the periodicity of fading, and the correlation among the channels have been exploited to formulate the sensor scheduling problem as a partially observable Markov decision problem (POMDP). Specific algorithms based on value iteration and pruning have been proposed in order to reduce the computational burden associated with the corresponding POMDP. The proposed scheduling mechanism is compared against a TDMA scheduling for a three-sensor network, and an average 22-32% improvement in energy consumption and slight improvement in reliability is reported.


The first of the new generation of Meteosat satellites, known as Meteosat Second Generation (MSG), was launched in August 2002. From its geostationary orbit, the satellite's radiometer, the spinning enhanced visible and infrared imager (SEVIRI), observes the full disk of the Earth with an unprecedented repeat cycle of 15 minutes in 12 spectral channels, having a sampling distance of three kilometres at nadir (1 km for the high resolution channel). For comparison, the first-generation Meteosat satellite covers only three spectral channels and has an imaging repeat cycle of 30 minutes, with a sampling distance between 2.5 and 5 km. MSG offers a wealth of new observational capabilities that could benefit weather forecasting and support severe weather warnings. Significant indirect benefits will come through improved weather forecasts that predict e.g. wind fields more accurately. With the beginning of MSG's operational phase on 29 January 2004, the satellite was renamed to Meteosat-8. The Meteosat-8 operational system also includes a suite of meteorological data which are extracted from the multi-channel image information, as e.g. winds, cloud analysis, atmospheric humidity and atmospheric instability over the entire field of view. This paper presents a general overview over the Meteosat-8 imagery and will especially focus on the meteorological parameters - including the underlying algorithms - that are extracted at EUMETSAT.


If S is a scheme of characteristic p, we define an F-zip over S to be a vector bundle with two filtrations plus a collection of semilinear isomorphisms between the graded pieces of the filtrations. For every smooth proper morphism X → S satisfying certain conditions, the de Rham bundles HdRn(X/S) have a natural structure of an F-zip. We givea complete classification of F-zips over an algebraically closed field by studying a semilinear variant of a variety that appears in recent work of Lusztig. For every F-zip over S, our methods give a scheme-theoretic stratification of S. If the F-zip is associated to an abelian scheme over S, the underlying topological stratification is the Ekedahl-Oort stratification. We conclude the paper with a discussion of several examples, such as good reductions of Shimura varieties of PEL type and K3 surfaces.


Early new deal diplomacy evolved largely around the debate over the collection of war debts, the question of an arms embargo, and the economic role of the United States in world affairs. In this atmosphere a debate on foreign policy began that revealed a decisive split in American attitudes. The sup porters of Franklin D. Roosevelt felt that a return to the Wilsonian concept of collective security would help to bring about a more stable international order. An opposing group of congressional isolationists, including Senator Hiram W. Johnson of California, argued that an active foreign policy would serve the nefarious interests of the business community. The two groups engaged in a debate that produced a drift toward isolationism. This drift was accelerated by the rising militarism in Europe and Asia, the failure of the Geneva Conference to promote worldwide disarmament, the inability to outlaw or control war, and the feeling that bankers and businessmen were leading the United States into an unwise foreign policy. Eager to avoid the mistakes of World War I the congres sional isolationists passed the Johnson Act of 1934. This legislation placed an embargo on lending to nations in default on war debts to the United States government, and it brought the forces of isolationism into the mainstream of American politics. As the first of a series of neutrality laws the Johnson Act began the process of establishing an isolationist foreign policy.1 In the debate over the position of the United States in international affairs, the role of California's Senator Hiram W. Johnson has been virtually ignored by diplomatic historians. The sensational munitions investigations of Senator Gerald Nye after World War I and the passage of more significant neutrality laws have overshadowed Johnson's contribution. As an influential member of the Senate Foreign Relations Committee and a man who had led progressive reform in Cali fornia as governor from 1910^1916 before becoming a senator, he played a significant role in the triumph of isolationist attitudes; his approach to foreign policy epitomizes the "isolationist impulse" of the 1930's.2 This article will examine Hiram Johnson's influence on the Senate Foreign Relations Committee from January, 1933, through the passage of the Johnson Act of April, 1934. This act was the culmination of the California senator's early crusade to isolate America from world problems. Examined with Johnson's


This study refers to the Y Generation's expectations of the job market. This generation is challenging for employers who want to attract good employees and retain them in an organization. Many public discussions touch this issue and talk about Generation Y's claims and exaggerated aspirations; employers complain about high expectations and lack of communication with older employees. This generation is the first which has grown up in the world of technology and computers and is totally absorbed by the Internet and virtual world. It represents different than previous generations' life priorities, different skills and needs. These particular factors that affect young people's attitude were included in this study.


On July 16th, 2020, the Canadian Association for Security and Intelligence Studies (CASIS) Vancouver hosted its third digital roundtable event of the year, COVID-19: China's Foreign Policy in the South China Sea. The presentation was conducted by guest speaker Mr. Brett Witthoeft, senior analyst in N39 International Engagement, at Maritime Forces Pacific (MARPAC) HQ at CFB Esquimalt, Canada's west coast naval formation. Mr. Witthoeft's presentation gave an overview of the South China Sea (SCS) and its importance as well as how this fits into the larger picture to the rest of the world. Subsequently, Mr. Witthoeft answered questions submitted by the audience, which focused on the ramifications of the SCS conflicts.
APA Citation
CASIS Vancouver. (2020). COVID-19: China's foreign policy in the South China Sea. The Journal of Intelligence, Conflict, and Warfare, 3(2), 54-60. https://journals.lib.sfu.ca/index.php/jicw/article/view/2408/1817.


Received: February 14, 2003; Revised: June 26, 2003A mathematical pultrusion model of a thermosetting matrix composite is presented. The en-ergy balance was solved by Finite Elements techniques using a program developed for this pur-pose. This model is applied to describe the temperature and resin conversion profiles along thedie. This study was developed considering different pulling velocity, die temperature, differentcomposite and different sections die. The model outcomes are verified through comparison withthe experimental results reported in the literature.


In this study, we consider the problem of actuator placement in the vibration control of flexible plates. Unlike earlier approaches based on enhanced controllability and/or improved performance measures, we consider the case of actuator placement based on robustness-with-respect to spatial variability of disturbances. As predicted from our extensive numerical investigation, when the spatial distribution of disturbances is known, then the resulting optimal location differs from the one predicted from controllability/LQR approaches. When the distribution is not known, then one may introduce an element of spatial robustness by considering the worst-case spatial distribution. Extensive numerical results are reported here which provide an insight on the judicious actuator placement when spatial distributions of disturbances are taken into consideration for actuator placement and controller design.


Dexamethasone induces thymic atrophy and thymocyte apoptosis. In the present study histological and ultrastructural changes which occur in the thymus of the mouse (BALB/c) following treatment with high (20 mg/kg) and low (8 mg/kg) doses of dexamethasone were investigated. In low dose treated mice, apoptotic cells were observed focally and localized mainly in thymic nurse cells (T.N.C.). A zone of intact thymocytes was formed in the medulla of animals receiving 20 mg/kg of dexamethasone as well as an increase in trans-endothelial vesicles and a decrease in the size of the vesicles in the cortical capillaries. The enveloped thymocytes within thymic nurse cells respond to dexamethasone through apoptosis, and these changes were seen to be more severe in mice treated with high doses of dexamethasone. The formation of apoptotic cells in the thymus caused by low dose dexamethasone mimics the physiological process of cell death. Differential effects of low dose and high dose dexamethasone may have pharmacological and immunological implications. MJIRI, Vol. 12, No.1, 65-69, 1998. Volume 12 Number 1 Spring 1377 May 1998