An optimized formulation of a sustained release tablet of Gliclazide was
developed. The use of Doptimal design with a polynomial statistical model to
analyze dissolution data reduced the number of laboratory tests required to
obtain an optimal dosage form. The final formulation contained 22 mg of Methocel&regE15LV,
16.5 mg Methocel&regE15 and 10.0 mg of Dibasic Calcium Phosphate per 30
mg Gliclazide sustained release tablet. Dissolution studies performed on
tablets from 5000 tablet test batches released greater than 90 percent of
loaded drug in eight hours. Drug release from the optimized tablets followed a
pattern more closely similar to zero-order than other mechanisms of drug
release tested. Storage of tablets in accelerated and ambient conditions for 6
and 12 months respectively did not alter any of the physico-chemical properties,
drug release or the drug release rate compared to initial observations and
dissolution data of the prepared tablets. The addition of potassium phosphate
and monosodium phosphate to the tablet reduced the effect pH has on Gliclazide
dissolution compared to the commercially available product.


The invention belongs to the field of chemical analysis and particularly relates to a method of detecting astaxanthin content in a prescribed preparation. The method provided herein includes the following steps: a), mixing a prescribed preparation sample to be detected, butylated hydroxyanisole and ethyl acetate, and filtering to obtain filtrate; b), detecting astaxanthin content in the filtrate by chromatography to obtain the astaxanthin content in the filtrate; c), acquiring astaxanthin content in the prescribed preparation sample to be detected, according to the astaxanthin content in the filtrate. By using the butylated hydroxyanisole and ethyl acetate as extracting liquids, the efficient of the extracting liquids in extracting astaxanthin in the prescribed preparation is improved, and detection accuracy for astaxanthin content is improved accordingly. Experimental results show that detection of the astaxanthin content in the prescribed preparation using the method provided herein has high specificity, and RSD values of repeatability, stability and recovery are all within 2%.


We previously conducted a preliminary analysis of the tasks performed by operators of hydraulic excavators, where the excavator is stationary and the implement is controlled by joysticks operated with the left and right hands. In the present paper, we put forward a detailed comparative analysis of the tasks for a hydraulic excavator and those for a wheel loader, of which operation of the latter requires simultaneous coordination of vehicular driving and implement operation whereas operation of the former does not. These analyses, based on Hierarchical Task Analysis (HTA), illustrate the complexity of equipment operation and distinguish the skills to be acquired for each machine. By employing HTA to decompose complex tasks into a hierarchy of goals and sub-goals, a better direction may be devised for how trainees spend their practice time for both the simulator and real equipment training phases. Future phases of this research will include input from experienced operators and trainers and extension of the HTA analysis to finer levels of description, including cognitive tasks.


At the 67th CFA Institute Annual Conference, held 4–7 May 2014 in Seattle, Robert Litterman interviewed William F. Sharpe to elicit his perspective on a number of investment issues, including the capital asset pricing model, asset allocation, behavioral finance, and retirement income. At the 67th CFA Institute Annual Conference, held 4–7 May 2014 in Seattle, Robert Litterman, executive editor of the Financial Analysts Journal, interviewed William F. Sharpe to elicit his perspective on a number of investment issues, including the capital asset pricing model, asset allocation, behavioral finance, and retirement income. Sharpe discusses the early days of his career, current investment topics, and his views on the future.


The workshop on Methodologies and Evaluation of Lexical Cohesion Techniques in Real-World Applications (ELECTRA 2005) was held in Salvador, Brazil on August 19 in conjunction with the 28th ACM Annual International Conference on Research and Development in Information Retrieval (SIGIR 2005). The aim of the workshop was to bring together researchers in NLP and IR to discuss the use of lexical cohesion in text applications, such as document and passage retrieval, question answering, topic segmentation and text summarization. There were a number of related workshops in the past: MEMURA 2004 Workshop on Methodologies and Evaluation of Multiword Units in Real-World Applications in association with the 4th International Conference on Language Resources (LREC 2004) [1], Multiword Expressions: Integrating Processing Workshop in association with the 42nd Annual Meeting of the Association for Computational Linguistics (ACL 2004) [2], and Multiword Expressions: Analysis, Acquisition and Treatment Workshop in association with the 41st Annual Meeting of the Association for Computational Linguistics (ACL 2003) [3]. The goal of this workshop was to address a wider range of lexical cohesion phenomena in text, not only multiword units, but also relations between words on the sentence, passage and document level, and how they can be useful for information retrieval applications.


This book offers engineers, contractors, and administrators a wide range of vital information and data on all aspects of highway design--particularly timely due to the current increase in highway construction and repair. It provides important information in a form that's easy to use, this guide--selected from Woods' Highway Engineering Handbook--covers not only construction procedures, materials, and maintenance, but also traffic patterns, contracts, administration and finance and landscaping.


hosted gold deposits that have been commonly interpreted as an orogenic or a Carlin-like gold system. One of the prolonged debates on the genesis of these deposits is the source of the ore fluids and other components in the fluids, with two contrasting models advocating its magmatic and metamorphic derivation. For most deposits, the evidence for the fluid source was ambiguous and less definitive. The Xiahe-Hezuo (XH) district in the western portion of the Western Qinling orogen provides an ideal opportunity to understand this issue. In terms of stratigraphic components and magmatic rocks, the XH district can be divided into the northern and southern parts separated by the NW-oriented Xiahe-Hezuo Fault that has a strike length of more than 300 km. The northern part is marked by Carboniferous cabonates and Permian clastic and carbonate rocks that are intruded by several major stocks or batholiths in the time period of 252 to 230 Ma. Geochemical and Sr-Nd-Hf isotopic constraints indicate that these rocks formed as a mixture or mantleand crustal derived melts in a continental arc setting related to the northward subduction of the Anyemaqen ocean, part of the Paleo-Tethys Ocean. The Southern part is stratigraphically dominated by Triassic clastic sequences that are intruded by numerous dikes of intermediate to felsic compositions. Geochronological and geochemical constrains on most dikes have been rare, but recent zircon U-Pb geochronology indicates that the dikes within and around the Zaozigou gold mines formed in the 249-221 Ma interval, consistent with the timing of granitoid intrusions in the northern part. A few tens of gold deposits and prospects have been demonstrated in the XH district, although most of them are poorly explored and studied. In the southern part of the district, they are mostly hosted in the Triassic clastic rocks and, less significantly, in the granitoid dikes. The Zaozigou gold deposits is the best representative with a proven reserve of ca. 80 t gold at an average grade of 6-10 g/t. It is hosted in the early Triassic calcareous and silty sandstones and granitoid to dioritic dikes that intrude the Triassic strata. Mineralization consists of disseminated gold-bearing arsenian pyrite and arsenopyrite in hydrothermally altered host rocks, with minor amounts of auriferous sulfide-bearing quartz-ankerite veinlets and stibnite-quartz-ankerite veins typically overprinting the disseminated ores. Gold is present mainly as invisible gold in arsenian pyrite (≤323 ppm Au) and arsenopyrite (≤1954 ppm), with some visible gold grains (1 to 5 μm) in paragenetically late stibnite and quartz from the auriferous veins. Ore-related sericite separates yield Ar/Ar plateau ages ranging from 230 ± 2.3 to 219 ± 1.1 Ma (1σ), whereas zircon grains both from mineralized and barren dikes have U-Pb ages of 248.9 ± 1.4 to 215.5±2.1 Ma (2σ). Analysis of sericite grains from the ore-related alteration assemblage yielded δDSMOW of -56 to -76 ‰ and δOSMOW 12.4 to 10.1 ‰ for the ore fluids assuming a mineralizing temperature of 250 oC. Fluid inclusion waters extracted from vein quartz have δDSMOW of -85.1 to -99.2 ‰ , whereas the calculated δOSMOW values for the equilibrated fluids range from -0.1 to 8.0 ‰. The isotope data thus indicate a magmatic derivation of the ore fluids, with additional meteoric components in late mineralizing stage. This view is partly confirmed by the geochronological constraints and consistent with carbon isotopes (δCV-PDB = -6.45 to -3.65%) of ankerite in the orebodies. Primary inclusions of magmatic sulfide (pyrrhotite, chalcopyrite, pyrite) and ilmenite with rounded to elongated shapes are present in the amphibole and plagioclase phenocrysts in porphyritic diorite or quartz diorite dikes that may or may not be mineralized. This observation is interpreted in terms of sulfur saturation and sulfide melt exsolution, likely caused by incursion of mafic magmas into an already existing, more evolved LI Jianwei, SUI Jixiang, JIN Xiaoye, WEN Guang and CHANG Jia, 2014. A Magmatic Related Gold System in the Xiahe-Hezuo District, Western Qinling Orogen, China. Acta Geologica Sinica (English Edition), 88(supp. 2): 751-752.


Aim: To evaluate the effectiveness of delayed implant placement in mandibular first molar by follow-up of patients for 6 months followed by implant placement. Materials and methods: Eight patients (five men and three women) aged 19 to 35 years were included in this study. Each patient had edentulous space in mandibular first molar for 3 months postextraction. After implant placement surgery the second stage surgical procedure was performed 3 months after the first procedure. The following parameters were evaluated at the time of implant placement and at second stage surgery: Implant mobility and soft tissue dehiscence clinically, peri-implant radiolucency and marginal bone loss evaluated radiographically.Results: The postsurgical healing period was uneventful for all patients. At second stage surgery, no peri-implant defects or implant mobility were observed (except in one patient).Conclusion: Successful osseointegration was observed in all patients. The soft tissue healing was satisfactory. Additional mucogingival surgery was not required before definitiveprosthetic rehabilitation.


13 3 Abstract: Authors have developed the research methodology for surveying the status and future considerations of the North Caucasus Federal District regions, identified constraining and motivating factors, produced definition of typology of the macro regional subjects in accordance with the results of the multidimensional bloc-based (economic, social, resource and industry-specific) approach in evaluation of generalizing static and dynamic indicators. This allowed authors to qualitatively describe the current level (highly-developed, moderately developed, developing and low-developed) and the rate (strong, moderate and noticeable) of socio-economic development of the regions for both Russian Federation (RF), as a whole and the North Caucasus Federal District (NCFD), in particular.


Selection Rhinometrv and open-mouth posture in young children. Gross, A. M., Kellum, G. D., Morris, T., Franz, D., Michas, C , Foster, M. L., Walker, M. E., Bishop, F. W. Department of Psychology, University of Mississippi, University 38677. American Journal of Orthodontics and Dento-Facial Orthopedics (1993) June, Vol. 103 (6), pp. 526-9. A biracial sample of 348 elementary school children who were in the first grade were assessed for open-mouth posture (OMP) in the natural environment. In addition, rhinometry was performed on 296 of the children. Means were computed for percent OMP and crosssectional nasal airway. Results indicated that, in general, these children exhibited relatively high rates of OMP. Boys displayed significantly greater OMP than girls, and black children showed significantly larger cross-sectional nasal areas than white children. A significant correlation between OMP and nasal area only was evident for children exhibiting OMP during more than 80 per cent of the observation intervals. The implications of the findings were discussed. Author. Head and neck reconstruction using the platysma myocutaneous flap. Ruark, D. S., McClairen, W. C. Jr., Schlehaider, U. K., Abdel-Misih, R. Z. Department of Surgery, Medical Centre of Delaware, Wilmington. American Journal of Surgery (1993) June, Vol. 165 (6), pp. 713-8; discussion 718-9. A retrospective analysis of our experience with 41 patients who received a platysma myocutaneous flap for reconstruction of intraoral and pharyngeal defects is presented. All patients had epiderr moid carcinoma of the head and neck region, with tumour size ranging from Tl to T4. The primary sites of malignancy were the oral cavity (61 per cent), the oropharynx (32 per cent), and the hypopharynx (7 per cent). Either radical or modified radical neck dissection requiring routine ligation of the facial artery was performed in all 41 patients. Adjuvant therapy included preoperative or postoperative radiotherapy (39 per cent) and preoperative chemotherapy (73 per cent). The mean hospital stay was 13 days. Flap-related complications occurred in eight patients (19 per cent) only. These included partial flap necrosis involving the epithelium alone, skin necrosis of the neck suture line, and fistula formation. Most complications resolved with local care only. Minor surgical intervention was required in three patients. There were no perioperative deaths. These results indicate that the platysma myocutaneous flap is a viable alternative in head and neck reconstruction. Author. Nasal lymphomas in Peru. High incidence of T-cell immunophenotype and Epstein-Barr virus infection. Arber, D. A., Weiss, L. M., Albujar, P. F, Chen, Y. Y., Jaffe, E. S. Division of Pathology, City of Hope National Medical Centre, Duarte, California 91010. American Journal of Surgical Pathology (1993) Apr, Vol. 17 (4), pp. 392-9." ' The incidence of non-Hodgkin's lymphoma of the nasal region is much higher in Peru than in the United States and is similar to the incidence of sinonasal lymphomas in Asian countries. To characterize these lymphomas, we evaluated the clinical, morphologic, and immunohistochemical features of 14 cases and also analyzed the cases for Epstein-Barr virus (EBV) RNA using a sensitive and specific in situ hybridization method. Morphologically, the cases consisted of nine large cell immunoblastic lymphomas, one diffuse mixed cell lymphoma, and two cases unclassifiable in the Working Formulation. Eleven cases demonstrated evidence of T lineage, two were of B lineage and one of indeterminate immunophenotype. In 13 of the lymphoma cases including all of the T-cell lymphomas, EBV RNA was detected in a high percentage of cells. Double-labelling immunohistochemical and in situ hybridization studies identified CD43 positivity in the cells labelling for EBV RNA. Much smaller amounts of EBV RNA were detectable in six of eight control benign nasopharyngeal biopsy specimens, and two were completely negative. These findings are similar to the prevalence of EBV-positive T-cell lymphomas in Asian countries and differ from the findings of the more common EBV-negative B-cell nasal lymphomas in the United States. These findings suggest that EBV plays a role in the development of nasal T-cell lymphomas and that the incidence of EBV infection may explain the reported 'East-West' difference in the incidence of nasal T-cell lymphomas. Author. Pure squamous cell carcinoma of the larynx with cervical nodal metastasis showing rhabdomyosarcomatous differentiation. Clinical, pathologic, and immunohistochemical study of a unique example of divergent differentiation. Goldman, R. L., Weidner, N. Department of Pathology, Mount Zion Hospital of University of California, San Francisco 94115. American Journal of Surgical Pathology (1993) Apr, Vol. 17 (4), pp. 415-21. We describe a unique case of pure squamous carcinoma of the larynx that developed a cervical lymph node metastasis showing rhabdomyosarcoma admixed with squamous carcinoma (that is, carcinosarcoma). The rhabdomyosarcoma showed foci immunoreactive to multiple cytokeratin monoclonal antibodies, as well as to markers for striated muscle, thus indicating true divergent epithelial and rhabdomyosarcomatous differentiation. Although the morphogenesis of carcinosarcomas remains controversial, the sequence of events for the current case favours sarcomatous transformation of the original carcinoma (that is, sarcomatous neometaplasia of the primary carcinoma clone). The possible contributory role of radiation therapy in this case in inducing such a change is noted. Author. Amygdaloid sclerosis in temporal lobe epilepsy. Hudson, L. P., Munoz, D. G., Miller, L., McLachlan, R. S., Girvin, J. P., Blume, W. T. Department of Pathology (Neuropathology), University of Western Ontario, London, Canada. Annals of Neurology (1993) Jun, Vol. 33(6), pp. 622-31. Hippocampal sclerosis is the sole abnormality found in approximately 65 per cent of all temporal lobe specimens resected for intractable temporal lobe epilepsy. Up to 27 per cent of en bloc temporal lobectomy specimens, however, show no definitive pathological changes. The lateral amygdaloid nucleus from eight consecutive patients who underwent temporal lobectomy in whom no definitive hippocampal pathology was present and corresponding tissue from eight consecutive patients with hippocampal sclerosis were subjected to quantitative estimation of neuronal density and astrogliosis. As compared to amygdaloid tissue from autopsy control subjects with no history of neurological disease, both the patient group with and that without hippocampal sclerosis consistently exhibited severe neuronal loss and gliosis with no quantitative differences between the two groups. Blinded clinical review of both groups of patients revealed that the development of hippocampal sclerosis was associated with a history of early brain insult; this history was absent in patients with isolated amygdaloid sclerosis. Neuropsychological testing prior to surgery demonstrated that patients with hippocampal sclerosis displayed a greater degree of memory impairment than did those without hippocampal sclerosis. We conclude that amygdaloid sclerosis occurs in the absence of hippocampal sclerosis, and that these patients form a distinct group with no history of early brain insult and milder memory impairment than that seen in patients afflicted with hippocampal sclerosis. Author. X-linked ataxia, weakness, deafness, and loss of vision in early childhood with a fatal course. Arts, W. F , Loonen, M. C , Sengers, R. C , Slooff, J. L. Department of Neurology, Westeinde Hospital, The Hague, The Netherlands. Annals of Neurology (1993) May, Vol. 33 (5), pp. 535-9. An X-linked recessive disease with, in almost all patients, a fatal course in early childhood, occurring in a five-generation family is described. The 12 affected boys had early-onset floppiness, ataxia,


The minimum Sr/sup 90/ content found in milk was 1.0 strontium units in January 1957 and September 1959 and the maximus value was 12.0 strontium units in December 1958. The Sr/sup 90/ content in dairy milk was somewhat higher in the autumn of 1957 when several nuclear tests took place. A considerable increase was registered in the winter of 1958 ard 1959 after a larger series of nuclear tests during 1958. Since the autumn of 1959, fall-out activiyy has decreased rapidly. In February 1960 about 0.5% as much activity as was measured in the second half of 1958 was found. This decrease is due to the temprary suspension of nuclear tests which began in November 1959. The systematic long-term study of decay curves of fall-out samples with high acitvity showed that in Europe highly active fallout represents an almost isolated set of fission products. Background due to previous tests was practically negligible. Sr/sup 90/ and Y/sup 90/ ccntant do not exceed 1% of fall-out activity at present. (auth)


Schwann cells (SC) do not express major histocompatibility complex (MHC) class II antigens under normal culture conditions. SC can, however, be induced in vitro to express MHC class II molecules by exposure to high concentrations of interferon‐gamma (IFN‐γ) and can present antigens to antigen‐specific T cell lines. In the present study immunohistochemical labeling showed that most SC (>90%) prepared from rat neonatal sciatic nerves expressed MHC class II molecules when cultured together with mycobacterial antigen and T cells, and as a consequence were able to function as antigen‐presenting cells in lymphoproliferation assays, without requiring pretreatment with IFN‐γ. Antigen or T cells alone were ineffective in stimulating MHC class II expression and induction of class II molecules was MHC restricted, requiring the presence of syngeneic T cells. Addition of monoclonal antibody DB1, directed against IFN‐γ to co‐cultures of SC and T lymphocytes stimulated with antigen, prevented the induction of MHC class II antigen on SC. When SC were incubated with recombinant (r)IFN‐γ alone, up to 50% of SC showed positive labeling for MHC class II antigen. This level of expression was enhanced to > 80% when recombinant tumor necrosis factor (rTNF) was also added. rTNF alone had no effect, and addition of DB1 antibody inhibited the synergistic effects of rTNF on MHC class II expression. The effects of rIL4 were also investigated but neither rIL4 alone nor rIL4 in combination with rIFN‐γ induced MHC class II expression by SC. These results show that in the presence of sensitized T lymphocytes and antigen, SC do not require pretreatment with exogenous rIFN‐γ to express MHC class II antigens and function as antigen‐presenting cells. T cell‐derived TNF and IFN‐γ appear to act as mediators of the T cell‐induced expression of MHC class II by SC.


CO2 is the most important greenhouse gas involved in climate change; it has been a concern for many years and will remain as such in the years to come. CO2 adsorption and CO2 utilization have been studied as methods to mitigate the concentration of the gas in the atmosphere by sequestering and transforming it into a value-added product, capable of being commercialized. With those aims in mind, CO2 reduction into 3D graphene was studied using a Zn–Mg mixture. The results show that Mg is the only reducing agent, and Zn acted as a porogen during graphene formation as the energy released by the reaction between CO2 and Mg is enough to evaporate Zn. Thus, Zn vapor increases graphene porosity and increases the contact of CO2 with Mg, yielding larger masses of graphene. A relationship between the Zn–Mg ratio and the reaction yield was found.


The ORF99 of Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus(HaSNPV)(Ha99) is one of the 20 genes that are unique to HaSNPV.Computer-assisted analysis revealed that open reading frame of Ha99 was 354 bp long in size encoded 118 amino acid residues with predicted 13 kDa molecular weight.SDS-PAGE and Western blot results suggested that Ha99 protein was expressed by using Bac-to-Bac system.The molecular weight of expressed protein is 13 kDa,consisting of the predicted molecular weight.The subcellular location was studied using EGFP-Ha99,which suggested that the Ha99 protein is primarily localized in the cytoplasm.The Ha99 was also detected at 6 h.p.i and remained detectable until 122 h.p.i.by RT-PCR,suggesting that Ha99 is a late expression gene.


Excerpt To the editor: It is important to be reminded (Ann Intern Med84:286-289, 1976) that dietary milk in its various forms does not suppress or inhibit gastric-acid secretion. However, the data ...


The auricle or pinna is subject to a large number of diseases. Those where surgery is the treatment of choice or those with an appearance mimicking a surgically amendable condition will be the focus of this article. Acquired problems only will be considered. Congenital conditions are not within our scope. Acquired surgically responsive lesions of the auricle can be divided into sun-induced and traumatic, with the bulk being neoplastic lesions initiated by ultraviolet radiation. The epidermis and dermis are thin with a variably thick, generally thin, subcutaneous layer separating the dermis from the perichondrium. Lymphatic drainage of the pinnal is made to the superficial parotid, retroauricular, and superficial cervical lymph nodes. The thinness of the skin backed by the relatively tumor-resistant elastic cartilage can affect both the clinical presentation and clinical behavior of some of the malignant neoplasms. but changes significantly in the organ transplant population (2.43 in kidney, 1.1:l in heart).4 Ultraviolet B radiation is the principal etiologic agent for both BCC and SCC, with the fairest skin being at the greatest risk.5


Since 1970s, the development of high technology especially the information technology has great impact on the progress of social economy. The utilizing and developing information technique midwifery the informatization. Logistics informatization is the spirit of modern logistics. Informatization has both positive and negative influence on the control of logistics cost. Only realizing these impacts can we impel the development of the logistics industry faster and healthier.


The need for this conference was established at the 4th All Ireland Conference on the Teaching of Computing held in Dublin in August 1996, where a workshop session on the use of Java as a first language proved to be the most popular event at the conference. The evaluation forms from the workshop indicated that a significant number of attendees were planning, or considering, using Java within their courses; and that many of the attendees were very unsure about the Java language and about the role which it could play within the curriculum.


Laser Research announces on a semimonthly basis the current worldwide information on all aspects of laser research and development, excluding applications. (MOW)


A muliti-channel nuclear data acquisition system composed of many detecting channels is introduced, with which radiation from the 4 MeV electrostatic accelerator can be monitored in time. Every channel adopts AVR chip microprocessor ATmega128 as host controller and transfers data through USB interface based on CH375. With great acquisition speed, short dead time and high counting rate, this system can detect and analyze many kinds of ra- diation, such as γ, X, fast-neutrons and so on. If some detecting sensors are changed and some parameters are adjusted, the system can be applied to radiation monitoring for facilities other than accelerators.


Based on various practical non-ideal factors in analog and mixed signal circuit design,a set of SIMULINK models are used to perform time-domain behavioral simulations of different Σ-Δ modulators.Simulation doesn't only include classical cascade structure,but also contains Multi-stage Noise Shaping one.By simulation and transfer functions calculation,this paper can analyze the influences of different non-ideal factors for different structures.


The modulated structure in solid solution Bi_2+ x Sr_2− x Cu_1+ y O_6+δ (0.1 < x < 0.6, y ∼ x /4) has been investigated by means of powder x-ray diffraction, electron diffraction, and transmission electron microscopy. The [010] component of the modulation vector decreases almost linearly with increasing x , from 5.2b ( x = 0.1) to 4.2b ( x = 0.5), where b is the unit length of the average structure along the [010] direction, and is little sensitive to excess oxygen content δ. A structure model of the modulation based on a periodic substitution of Sr for Bi and formation of Bi blocks whose size varies with x is proposed. Relations among various modulations appearing in other related phases such as the Pb-substituted 105 K T _ c phase are discussed.


This paper presents the architecture of the non-contact sensor for measuring the rope swinging angle in two planes. The sensor were dedicated to the all kind of the crane device, especially to overhead travelling crane. The main objective of this statement applies a solution for improving early developed and described non-contact vision swinging sensor. In the article, the author main attention has been focused on issues related to the possibility of using a "smart camera" device as a full functional contactless two-dimensional sway sensor. All tests and considerations were conducted on the scaled physical model of overhead travelling crane with hosting capability 150kg.


The large rise in permittivity experienced by transducer ceramics when subjected to stress parallel to the polar axis can reduce the utility of these materials. Measurements are described on PZT‐4 and PZT‐8, representative of ceramics useful for high‐power high‐stress applications, for which a stabilizing heat treatment has reduced the change in permittivity. It is shown that the stabilizing effect is permanent. Several stress cycles to 10 or 20 kpsi also stabilize these ceramics. It is shown that the stabilization with stress for stress cycles to 10 kpsi is not permanent. Measurements were made over an aging range from one day to six months.


Objective:To investigate the effects of ROCKⅠ and ROCKⅡ on the expression and activity of matrix metallopr-oteinases 2(MMP-2) of vascular smooth muscle cells(VSMC) induced by PDGF-BB.Methods:ROCKⅠ and ROCKⅡ genes were down-regulated by siRNA transfection.The expression levels of ROCKI/II and MMP-2 were detected by western blot,and the activity of MMP-2 was assessed by Gelatin Zymognaphy.Results:By siRNA transfection,the protein expressions of ROCKⅠ and ROCKⅡ were down regulated by 79.8% and 70.1% respectively;The expression and activity of MMP-2 were inhibited by the down-regulated ROCKⅠ and ROCK Ⅱ,whereas the effect of ROCK Ⅱ was more marked.Conclusion:Both ROCK Ⅰ and ROCK Ⅱ siRNA decreased the expression and activity of MMP-2.


We can perform the geometric argument of general relativity principle on (unstable) Riemann space-time just inspired by nonlinear representation of supersymmetry(NLSUSY), whose tangent space is specified by Grassmann degrees of freedom y for SL(2,C) besides the ordinary Minkowski one x a for SO(1,3) and obtain straightforwardly new Einstein-Hilbert(EH)-type action with global NLSUSY invariance (NLSUSYGR)) equipped with the cosmological term. Due to the NLSUSY nature of space-time NLSUSYGR would breaks down(Big Collapse) spontaneously to ordinary E-H action of graviton, NLSUSY action of Nambu-Goldstone fermion y and their gravitational interaction. Simultaneously the universal attractive gravitational force would constitute the NG fermion-composites corresponding to the eigenstates of liner-SUSY(LSUSY) super-Poincare space-time symmetry, which gives a new paradigm for the unification of space-time and matter. By linearizing NLSUSY we show that the standard model(SM) of the low energy particle physics can emerge in the true vacuum of NLSUSYGR as the NG fermion-composite massless eigenstates of LSUSY super-Poincare algebra of space-time symmetry, which can be understood as the ignition of the Big Bang and continues naturally to the standard Big Bang model of the universe. NLSUSYGR can bridge naturally the cosmology and the low energy particle physics and provides new insights into unsolved problems of cosmology, SM and mysterious relations between them, e.g. the space-time dimension four, the origin of SUSY breaking, the dark energy and dark matter, the dark energy density (cid:24) ( neutrino mass ) 4 , the tiny neutrino mass, the three-generations structure of quarks and leptons, the rapid expansion of space-time, the magnitude of bare gauge coupling constant, etc


The purpose of this research is to see the effect of motivation on taxpayer compliance in the payment of Personal Income Tax in the industrial Entrepreneur beads Plumbon Gambang village. Inferential data processing analysis tool that uses two confirmatory factor analysis to determine the contribution of each indicator of motivation, compliance and simple linear regression analysis to determine the effect of motivation on adherence to pay taxes. The results showed extrinsic factors contribute most strongly to the motivation, the accuracy of the filling factor contributing the most powerful SPT to pay tax compliance, test results obtained statistically significant positive effect on adherence motivation to pay taxes, but the effect is still weak is only about 47.1%. Keywords: Motivation Taxpayer, Taxpayer Compliance Rate


The LASSO is a widely used shrinkage and selection method for linear regression. We propose a generalization of the LASSO in which the $l_1$ penalty is applied on a linear transformation of the regression parameters, allowing to input prior information on the structure of the problem and to improve interpretability of the results. We also study time varying system with an $l_1$-penalty on the variations of the state, leading to estimates that exhibit few ``jumps''. We propose a homotopy algorithm that updates the solution as additional measurements are available. The algorithm takes advantage of the sparsity of the solution for computational efficiency and is promising for mining large datasets. The algorithm is implemented on three experimental data sets representing applications to traffic estimation from sparsely sampled probe vehicles, flow estimation in tidal channels and text analysis of on-line news.


Cell migration plays an essential role in many of physiological and pathological processes, including morphogenesis, inflammation, wound healing, and tumor metastasis. It is a complex process that involves multi-scale interactions between the cell and the extracellular matrix (ECM). Cells migrate through stromal ECM with native and cell-derived curvature at micron-meter scale are context-specific. How does the curvature of ECM mechanically change cell morphology and motility? Can the diverse migration behaviors from genetically identical cells be predictively using cell migrating data? We address these questions using an integrated computational and experimental approach: we developed three-dimensional biomechanical cell model and measured and analyzed a large number of cell migration images over time. Our findings suggest that 1. substrate curvature determines cell shape through contact and regulating protrusion dynamics; 2. effective cell migration is characterized with long cellular persistence time, low speed variation, spatial-temporally coordinated protrusion and contraction; 3. the cell shape variation space is low dimensional; and 4. migration behavior can be determined by a single image projected in the low dimensional cell shape variation space. INDEX WORDS: Cell migration, Cancer invasion, Substrate curvature, Morphological dynamics, Cell-extracellular matrix interaction, Spatial-temporal interaction, Cell motility, Persistent random walk INTEGRATED MATHEMATICAL AND EXPERIMENTAL STUDY OF CELL MIGRATION AND SHAPE


Abstract This work describes the synthesis and characterization of a highly reactive cationic borole. Halide abstraction with Li{Al[OC(CF3)3]4} from the NHC‐chloroborole adduct yields the first stable NHC‐supported 1‐(MeNHC)‐2,5‐(SiMe3)2‐3,4‐(Ph*)2‐borole cation. Electronically, it features both a five‐membered cyclic conjugated 4 π‐electron system and a cationic charge and thus resembles the yet elusive cyclopentadienyl cation. The borole cation was characterized crystallographically, spectroscopically (NMR, UV/Vis), by cyclovoltammetry, microanalysis and mass‐spectrometry and its electronic structure was probed computationally. The cation reacts with tolane and reversibly binds carbon monoxide. Direct comparison with the structurally related, yet neutral, 1‐mesityl borole reveals strong Lewis acidity, reduced HOMO–LUMO gaps, and increased anti‐aromatic character.


Targeted protein depletion using a conditional degron is a powerful method to probe the role of proteins in living cells because of the speed with which depletion can be induced and its reversibility. The auxin‐inducible degron (AID) is one of the most common degron‐based technologies used in cell biology. We recently established an improved system, called AID2, which involves expressing a mutant E3 ligase subunit, OsTIR1(F74G), and fusing a protein of interest to the mini‐AID (mAID) tag, and that employs a new and more potent ligand, 5‐phenyl‐indole‐3‐acetic acid (5‐Ph‐IAA). The AID2 system overcomes some of the drawbacks associated with the original AID system, i.e., leaky degradation without auxin and the requirement of high auxin doses. With AID2 it is, therefore, now possible to control a degron‐fused protein more precisely, enabling target proteins to be degraded with a half‐life of 10 to 45 min via the addition of a low dose of 5‐Ph‐IAA. Importantly, in AID2, it is not necessary to control the expression of OsTIR1(F74G) for suppressing leaky degradation and a parental cell line constitutively expressing OsTIR1(F74G) can be used for the generation of multiple mAID‐tagged proteins. Here, we describe a protocol for the tagging of endogenous proteins with mAID in diploid HCT116 cells. Our protocol can be applied to other mammalian cell lines and will enhance the utility of AID2 for studying protein functions in living cells. © 2021 Wiley Periodicals LLC.


Background Background Increasing prevalence of Increasing prevalence of recreational cannabis use among the recreational cannabis use among the young population has stimulated debate young population has stimulated debate on the possible effects of acute and long-on the possible effects of acute and long-term use. term use.


Combined with the characteristics of highway industry,the paper puts forward the index system of performance evaluation in the public highway enterprises.Based upon the principle of dynamic comprehensive evaluation, a new method of performance comprehensive evaluation with time series of public highway enterprises is proposed, which is composed of combination weighting method and ideal point method.Finally as an example the method is given to evaruate public highway companies.In the dynamic comprehensive evaluation model,the paper adopts the order relation analytic method and the entropy method to determine the index combinational weight,considering the virtue of the subjective weight and the objective one.It can improve the accuracy of the evaluation.


Genu varus is one of the malalignment of the lower limbs, the failure to correct it leads to secondary abnormalities in adulthood. The purpose of this study was to investigate the effects of a corrective exercise program on ground reaction forces, loading rates, impulses and free moment during stance phase of walking. 17 children with genu varus were volunteered to participate in this study (Age:11.71±1.68 years, Height:1.40±0.09 meter, Weight:35.14±11.47 Kg, and BMI:17.49±3.61Kg/M). Ground reaction forces were recorded with two Kisler force plates during pre and post-test. At the dominant limb, the amount of time to peak in the mediolateral ground reaction force component during heel contact decreased by of 61.90% (P=0.011). Also, the time to peak of the vertical ground reaction force component during mid-stance tend to increase significantly by 11.47% during the post-test compared to the pre-test (P=0.063). The values of peak ground reaction force components, loading rate, impulse and free moment did not show any significant differences between pre and post-test. The findings showed that the corrective exercise trainings used in the present study had the most effect on the time to peak components of the GRF, but there were no significant effects on the loading rate, impulses, and free moment components. The corrective exercises used in the present study have had the most effect on the time to peak of ground reaction forces and improve them. On the other hand, these exercises did not have any significant effect on the vertical loading rate, impact and free moment values.


Once believed to be the great equalizer—a space in which racial, gender, and other social inequalities would be replaced by a discourse of democracy and freedom for all (Rheingold, 1993)—the Internet has instead become both a novel medium and a new site through which various social inequalities are produced, reproduced, and upheld. Hence, understanding the ways in which racial, ethnic, gender, age, and sexual identities are taken up on line is central to understanding how individuals make sense of self and community. First, no object, event, or social identity exists prior to social interaction; rather, meaning is created and reproduced through interaction and interpretation. Thus, the meanings of social identities, such as "Black," "White," "boy," "girl," ABSTRACT


We study the sensitivity of the collective transverse in-plane flow to the symmetry energy and its density dependence at Fermi energies and higher incident energies. We find that collective transverse in-plane flow is sensitive to the symmetry energy and its density dependence at Fermi energies whereas it shows insensitivity at higher incident energies.


Provided is a method for synthesizing pyrroloquinoline quinine in vitro by utilizing bacteria cell disruption supernatant and adding a pyrroloquinoline quinine synthesis precursor-artificially synthesized polypeptide. The method comprises: inoculating producing bacteria of pyrroloquinoline quinine into a fermentation medium according to a proportion of 5%, and culturing for 3d in a shaking way at 28°C to obtain bacterial suspension; carrying out high speed centrifugation on the bacterial suspension to obtain thalli; using a buffer solution to suspend the thalli; after that, crushing by using an ultrasonic method, carrying out high speed centrifugation, and taking supernatant; and adding an artificially synthesized precursor into the supernatant, and carrying out a reaction for 12-26h at the constant temperature of 35-50°C.


Field and greenhouse experiments were conducted to study the epidemiology of rust ( Uromyces appendiculatus ) on beans ( Phaseolus vulgaris L.) in Ethiopia. The experiments were conducted under low input conditions reflecting the traditional bean production practices. Surveys identified five major diseases. Bean rust, bacterial blight and anthracnose were widely distributed. Angular and floury leaf spots were prominent in the humid west. Disease severities depended on regions, cropping practices and seasons. Strong associations between sowing date and rust severity and between bacterial blight and weediness or plant density were found. Artificial differences in rust epidemics produced large differences in crop growth, yield and yield loss. Multiple regression models were developed to estimate yield and yield loss. Yield and yield loss were best estimated by leaf area index and rust severity during flowering and late pod setting stages. Differences were found in the velocity of focus expansion (3 to 16 cm day -1 ) when susceptible and resistant bean cultivars were mixed at different proportions. The velocity of focus expansion increased linearly with the logarithm of the fraction of susceptible in the mixture. Five components of partial resistance were evaluated in a bean rust pathosystem. Differences between cultivars were largest for infection efficiency and sporulation capacity. Correlations existed between latency period and infection efficiency, infection efficiency and pustule size, and sporulation capacity and pustule size. Latency period, infection efficiency and pustule size can be used in screening for partial resistance.


This study aims to identify the differences between depression and life stress in exercise behavior change stage of some female college students. For the purpose, the study selected 250 female college students through convenience sampling and interviewed them with an self-administered questionnaire. A total of 192 copies of the questionnaire were used for the final analysis except 58 ones whose responses were insincere. As a result, there was a significant difference in depression according to grades, economic status, drinking state, smoking and changes of exercise, and there was a significant difference in life stress according to grades, residental state, perceived health and exercise behavior change stage. Based on the results above, it was suggested that to decrease depression and life stress of female college students, their health behaviors should be encouraged. Especially, to lead them to have regular and continuous exercise, differentiated and individualized exercise and educational programs should be developed in each step of exercise.


Desiccated coconut waste sorbent (DCWS), a byproduct of coconut milk processing, was studied as a sorbent for Hg(II) sorption. Energy dispersive X-ray analysis indicated that the DCWS mainly contained C, N, and O, while the Fourier transform infrared measurements confirmed the existence of hydroxyl, carboxyl, and amine groups on the DCWS surface. The point of zero charge (pHpzc) and cation-exchange capacity (CEC) values were 6.05 and 2.02 meq/100g, respectively. The batch equilibrium data were fitted well by the Langmuir isotherm model with a maximum sorption capacity, qmax of 500 mg/g, while the kinetic sorption data were found to follow a pseudo-second-order kinetic model. A column sorption study showed that the sorption capacity increased and the breakthrough time decreased with the increase in the initial Hg(II) concentrations. The regeneration studies revealed that the DCWS could be regenerated and reused.


The fundamental figure of merit that specifies the ultimate performance of cellular systems is the per-cell spectral efficiency. The underlying tacit assumption in previous spectral efficiency analyses is that all active users are (reliably) decoded, regardless of their received powers. Unfortunately, in practice, this assumption may not hold and we consider an alternative approach. Assuming single cell-site processing, four types of multiuser detection strategies are considered: (1) the "conventional" matched-filter detector; (2) the linear MMSE detector; (3) a detector that "optimally" decodes the transmissions of the maximum decodable subset of intra-cell users, referred to as the "single-cell optimum (SCO) detector"; (4) an "optimum" detector referred to as the "single cell-site processing optimum (SCPO) detector". The strategies are analyzed and compared in terms of their outage constrained capacities, analytically derived as functions of the fraction of undecodable users (FUU), equivalent to the outage probability.


Early prediction of clinical deterioration to reduce recurrent hospitalizations for acute heart failure (HF) and keep at home the outpatient with chronic HF is top-ranking in the agenda of health care systems. Indeed, hospitalizations account for the majority of HF expenses with about a 35% mortality and readmission rate at 1 year after discharge in Europe.1,2 Several strategies have been developed for remote monitoring of the outpatient with the aim of interrupting the progression from excessive fluid accumulation, decompensation, and hospitalization. They included monitoring of body mass, symptoms, ECG, blood pressure, heart rate, impedance, or atrial arrhythmia.3 Most of these have failed to demonstrate a reduction of readmission rate or death, while implantation of a pulmonary artery pressure monitor showed some benefits.4,5 This issue of the Journal features a report by McDonald and colleagues who designed a clinical trial aimed at evaluating whether daily remote monitoring of circulating natriuretic peptide concentrations integrated into a home health monitoring programme could improve outcome in the outpatient setting.6 The HOME HF study was conceived by the group that designed one of the most original studies on natriuretic peptides in chronic HF, the STOP-HF trial.7 The trial showed that patients identified by an elevated concentration of NT-proBNP could benefit from intensified cardiac therapy. Monitoring natriuretic peptides is being used in several contexts: general practice, internal medicine, and cardiology. A particularly sound setting for natriuretic peptide monitoring is its use at home: here is HOME HF, a randomized clinical study turned into observational due to an unexpectedly low rate of enrolment of patients. A pilot study in the US had already demonstrated that home BNP testing was feasible with a finger-stick test in high-risk HF outpatients.8 The present HOME HF study was originally conceived as a prospective, multicentre, three-arm randomized


Nanostructured Ni/WC-Co composite coatings free of cracks and pores have been prepared by laser cladding on 45 carbon steel.The microstructures and phase in the clad coatings were analyzed by XRD,SEM,EDS and AFM analysis methods,other than,the fracture toughness was firstly characterized by the indentation method.The results indicate that the coatings are mainly composed of carbides such as W2C、Fe3W3C and(Cr,Fe)23C6 which dispersedly distribute in the γ(Fe-Ni) substrate.The carbides with network structure among which other fine carbides dispersedly distribute can be obtained under sound process parameters.Under this condition,fracture toughness Kc of nanostructured Ni/WC-Co composite coatings improved about 1.2 times,compared with Ni/WC-Co composite coatings prepared by the traditional spray method,which demonstrates that nanometer phases can serve the anti-cracking function.


Though Dickens is best known for his unique characters, he is also associated with unforgettable descriptions of London. These memorable cityscapes will be used here as a springboard to conduct
an in-depth analysis of Dickensian landscapes in general. In the wake of Malcolm Andrews's study of Landscape and Western Art, the word landscape is understood here as a twofold process in which land is not just perceived as landscape but actually built into art; in other words landscape is defined here as land "aesthetically processed" (Andrews 1, 7), or to paraphrase Simon Schama in Landscape and Memory, as a way of elaborating on land as raw matter (10).1 It is this complex construction of landscapes—which in this instance are made of words—that the following collection of articles brings to light. They consider how Dickens combined what he saw with imaginary constructions, to build the unique cityscapes we all know so well. They show that Dickens's landscapes were informed by other artistic landscapes as well as by actual views of Victorian scenery. Unravelling the cultural influences, myths and memories that influenced his writing in the building of such landscapes, they tackle the question of mental landscapes. Mindscapes feature in fact prominently in this selection of articles.
These papers show how Dickens framed the scenery that he chose to depict and how his landscapes provide a setting for other views. Far from being mere backdrops, however, these landscapes always complement what they frame or foreground in subtle and complex ways. Some of them even seem to exist in their own right and not as mere frameworks for other subjects. This collection of essays examines the very nature of Dickens's response to his surroundings. The reader's experience of Dickensian landscapes is scrutinised and their sensory, personal but also spiritual and aesthetic dimensions are explored in detail. Following a pictorial model, the very composition of these landscapes is also taken into account—that is to say their subject matter, framing, foreground, middle ground and background. The feeling of unity that each landscape does or does not convey is also considered.
The articles further highlight how Dickens contributed, through his writing of landscapes, to making their surroundings more intelligible to readers. Dickens thus shed new light on Victorian scenery. His literary representation of contemporary landscapes recomposed reality and produced aesthetic emotions that made it possible for his readers to take a step back, to apprehend and appreciate their environment differently. Victorian urban or industrial areas must indeed have seemed disconcerting, baffling, inhospitable and even hostile. In this respect, such areas could be compared to a "new wilderness" (Andrews 18). Through his writing, Dickens endeavoured to make sense of this modern wilderness.
Last but not least, the contributions to this collection examine the opposition between cityscapes and landscapes and its implications. They show that this opposition dissolves, in the last analysis, into a set of complex issues that both polarise the dichotomy between urban and rural areas, and paradoxically enough connect them even more narrowly. This involves what the geographer Denis Cosgrove has defined as the insider/outsider opposition, in which insiders experience the landscape without seeing it as such, while outsiders admire it without noticing the experience of its inhabitants.


A major problem with Brain Computer Interface (BCI) technology is the variability of performance when applied to multiple users. We introduce a user-specific training scheme that builds a signal template specific to each user based on EEG recordings. As a feature we use the slow cortical change associated with a movement known as the Bereitschaftspotential (BP) measured using one bi-polar channel placed between C3 and A1 in the 10-20 standard electrode scheme. Signal processing techniques such as embedding, median and exponential weighting filters as well as normalisation of data and simulated annealing are implemented to make the template as robust as possible. Results still indicate a large variability in performance with accuracies from 59% up to 86%. It is expected that the results of this classification will be most useful in a multi-feature classification scheme. The simplicity of the training protocol and the number of electrodes used for detection are useful when considering clinical application of BCIs.


A thesis presented to the University of Science and Technology in fulfilment of the requirements for the Award of the Degree of Doctor of Philosophy (Mining Engineering),1993.


Unmanned aerial vehicles (UAVs) play an essential role in scenarios such as smart grid data collection and power line inspection for their maneuverability and low cost. However, the most obvious defect of UAVs is still the energy problem. The battery life of UAVs is too short of completing long-term tasks. Therefore, this paper proposes a distributed cooperative and continuous coverage strategy for UAVs. When the UAV is short of power, we select the path through the relay algorithm and send backhaul information such as the remaining power to the macro base station (mBS). mBS will send auxiliary UAVs to replace UAVs with weak power to complete the task of UAV replacement. We jointly optimize the relay information transmission path and UAV trajectory to achieve the goal of minimizing the total energy consumption of the system. The simulation results show that the optimization algorithm can significantly reduce the energy consumption of UAVs.


The government as the provider of public services often creates dissatisfaction for the community, this shows that there is still a lack of implementation of good governance, which can lead to maladministration and harm the community. The purpose of this study was to describe the conditions of the implementation of Good Governance on the process of public services and the quality of public services provided by the District government to the community. The research method used is descriptive qualitative in order to explore the problems and modes of public service delivery in sub-district units. Based on the research findings, it shows that overall the implementation of public services observed from 9 aspects or elements in the four sub-districts in Pekalongan City can be said to be relatively good enough and even good in its implementation. In general, the problems that are obtained from the results of all observed aspects that occur in the four (4) districts are related to the 6th point of implementing competence, the 8th point of complaint handling, and the 9th point of infrastructure. The results of this study indicate that descriptively, the implementation of Good Governance which is observed from the aspects of transparency and accountability has generally been applied in the organization of the four sub-districts in Pekalongan City but has not been fully implemented properly. Meanwhile, inferentiallly the implementation of Good Governance has a positive and significant effect on public services in the four districts with different levels of influence in each District Office.


OBJECTIVE: To assess pulmonary function in children and adolescents subjected to correction of rheumatic valve disease in order to quantify changes caused by factors inherent to surgery and rheumatic heart disease METHODS: This was a longitudinal and quantitative intervention study, undertaken at a children's hospital that is a center of excellence for the state of Pernambuco (Instituto Materno Infantil de Pernambuco), between December 2004 and May 2005. Eighteen children suffering from rheumatic fever and indicated for surgery to repair or replace the mitral valve were assessed preoperatively and again on the first and fifth postoperative days. The parameters recorded were minute volume, rapid shallow breathing index, peak expiratory flow, forced vital capacity and inspiratory capacity RESULTS: All patients were aged 8 to 17 years (mean 12.4±2.1), they had a mean body mass index of 16.1±2.2, and were weaned off invasive mechanical ventilation during the first 10 postoperative hours. All parameters had undergone significant deterioration on the first day (statistically significant, p 0.01), without returning to baseline levels. CONCLUSION: We observed that the pulmonary dysfunction that results from this type of heart surgery is maintained until at least the fifth postoperative day. It appears that this dysfunction is influenced by the pain and mechanical alterations caused by sternotomy and reduced pulmonary compliance post surgery.


Objective To explore the efficacy and tolerability of treatment with aripiprozole or aripiprozole combined with perphenazine following a switch from prior antipsychotics in inpatients with acute schizophrenia.Methods Patients enrolled this study began to take aripiprozole and their prior antipsychotics were tapered off.After two weeks treatment, all patients stop taking prior antipsychotics and randomly allocated to receive aripiprozole combined with placebo ( single group) or perphenazine combined with perphenazine ( combined group) for the treatment of 8 weeks.Positive and Negative Symptom Scale ( PANSS) and Clinical Global Impression Severity ( CGI-S) were used to assess the efficacy.Personal and Social Performance ( PSP) for social function,Simpson-Angus Rating Scale ( SAS) ,the Barnes Akathisia Scale ( BARS) ,and the Abnormal Involuntary Movement Scale ( AIMS) for tolerability and safety,Drug Attitude Inven-tory ( DAI-10) for attitude to taking drug.Results The patients of the two groups showed significant improvement in total scores,positive and negative symptoms scores,and PANSS scores of CGT-S after treatment (P0.05) .There were no significant differences in PANSS total score and CGI-S score between the two groups after 8 weeks treatment.Patients in single group had significantly higher scores in PSP and DAI than that in combined group (P0.05) .Conclusion Aripiprozole would have better efficacy and tolerability in the treatment of schizophrenia,and could improve the patients' social function and attitude to taking drug.


Continuous porous TiO2 fibers were synthesized by a sol-gel method using butyltitanate as a precursor.The as-synthesized products were characterized by scanning electron microscope,transmission electron microscope,X-ray diffractometer,Fourier trans-form infrared spectroscopy and specific surface area analyzers.The results show that the continuous TiO2 fibers calcined at 500 ℃ are radial ordered aggregates of the dense small grains,and the products are co-crystals of anatase and rutile phases.The fibers have the length of several meters and the diameter of 20-30 ?m.The continuous TiO2 fibers exhibit a layered structure.It is indicated that the continuous TiO2 fibers with the porous structure has the specific surface area of 26.66 m2/g,the most probable pore diameter of 0.94 nm and a wide pore size distribution.


A planar low‐profile 4 × 4 beam reconfigurable array antenna using electronically controllable method at X‐band is presented. A novel switchable slot‐coupled microstrip feed structure (SMFS) is employed in the design of the antenna, which can provide a 180° phase difference in a wide frequency band. The antenna element is composed of an SMFS, a 2 × 2 parasitic square metal patch array, and a DC bias circuit. By switching the p‐i‐n diodes on the SMFS for all antenna elements, four radiation patterns of the designed array antenna can be reconfigured. The measurement results indicate that the designed antenna has achieved good impedance matching over a wide overlapped relative bandwidth of 24%. Benefiting from the advantages of wideband operation in four dynamical reconfigurable beams, the proposed array antenna is quite suitable for intelligent spatial perception, multi‐beam, and anti‐interference wireless communication systems.


he paper presents a procedure for studying the stability of modeling an artificial neural network as applied to the thermal characteristics of machine tools. The topicality of this procedure is dictated by the ambiguity of the results generated by the neural network when constructing the predicted thermal characteristics of machine tools. Therefore, to select one of the possible solutions generated by the neural network, it was proposed to use two criteria. The effectiveness of their use is confirmed by the presented machine experiments. The methodology proposed in this work has made it possible to form a generalized concept for studying the effectiveness of the use of neural network technologies in thermal modeling of machine tools. This concept defines a typical set of variable modeling parameters, a basic mathematical model based on a modal approach, and an architecture of a typical software tool that can be developed to study the effectiveness of artificial neural network modeling. For each variant of the input data of the network, the following parameters were varied: the number of neurons in the hidden layer; the size of the input and output vectors; input vectors error; the size of the training, validation and test sample; functional features of thermal characteristics supplied to the network input or their multimodality; the presence and absence of normalization of the input vector. The paper presents experimental thermal characteristics for two spindle speeds of a vertical CNC machine. The results of the machine experiment are presented for six variants of the variable parameters of the mathematical model. The software tool used to carry out the machine experiment was developed in Matlab.


Objective
To evaluate the value of S-Detect technology of ultrasonography in the diagnosis of thyroid tumors.

Methods
Ninety-three thyroid tumors in 93 patients were enrolled in the group. A varied image features of the thyroid masses in gray-scale ultrasonography were analyzed by S-Detect technology and experienced doctor separately. The results were compared and the diagnostic ability were also compared between the two methods.

Results
There were 44 malignant tumors and 49 benign tumors in these thyroid nodules. The sensitivity of S-Detect technology in the diagnosis of thyroid malignant tumors was higher, up to 88.7%. In the five image features of the thyroid tumors in gray-scale ultrasonography, the result of composition of the mass obtained by S-Detect was the most consistent with that of the doctors and Kappa value was 0.89.

Conclusions
S-Detect is a kind of computer-aided diagnosis system, which is suitable for the ultrasound beginners in the diagnosis of thyroid tumors.

Key words:
Ultrasonography; Thyroid neoplasms; S-Detect technology


The method of synthesis for calculating the reliability of a complex network was developed by Woodcock. However, he experienced some difficulty in properly incorporating s-dependency, and this often necessitated considerable manipulation of the network beforehand. This difficulty is overcome in the present method by working with algebraic expressions involving component failure probabilities, and combining these expressions according to a simple set of rules. Experimental results are encouraging.


1. INTORODUCTION The National Institute of Environmental Studies Japan proposed a concept of floating wind power plant [1], which has no mooring system but moves with sails and struts. The mobility of the structure is the key of this concept, since if the structure moves, it could maximize the generated power to take an appropriate route and it could evacuate from high seas. The structure composed of slender beams and lower-hulls so that the structure is constructed in lightweight possible for its propulsive performance. The sizes of the structure are 1,880m length, 70.2m width and 20m draught. Eleven 5MW class wind turbines are supported by two lower-hulls. The structure is advanced with sails, and it is navigated so that wind turbines are in service at beam wind. Many vertical struts are equipped on lower-hulls, which induce a lateral lift force to counter the wind drag force. We call this structure VLMOS (Very Large Mobile Offshore Structure). To find the optimum routine to maximize the generated energy is very important to increase the energy profitable ratio which is defined as the ratio of net-output energy to total input energy through the lifetime of structure. Thus, we aim at building logic for finding optimum route with consideration of stormy weather and the rate of wind power in this project. The target figure of the rate of wind power is more than 40% of the maximum, in another word more than 40% of the capacity factor. Another important issue is the structural strength. The structure is designed to have enough strength in 6m significant wave height, but she should evacuate if the significant wave height exceeds 6m. This design concept is different from that of the conventional ships or the conventional offshore structures. Thus, they are anxious to use a conventional methodology for estimate of fatigue damage in which an averaged long term sea condition is used. In this study, we use the result of a navigation simulation for estimate of the fatigue damage to improve the methodology more realistic one than conventional one.


This is the second time that I've been presented an opportunity to interact with you through the pages of this magazine & before going any further I would like to congratulate everyone of you for the inauguration of Asian Clinic at Greater Kailash in Delhi. The clinic which can be described as a luxury healthcare experience brings a completely new perspective to healthcare. As you walk through the reception you are not greeted by the familiar stench of antiseptic but instead by beautiful hostesses with their warm and welcoming smiles, a waft of fresh cut flowers and the faith that you are among the best medical professionals in the country.


Tunneling metal–insulator–metal (MIM) junctions can exhibit an open-circuit photovoltage (OCPV) response under illumination that may be useful for photodetection. One mechanism for photovoltage generation is hot carrier tunneling, in which photoexcited carriers generate a net photocurrent that must be balanced by a drift current in the open-circuit configuration. We present experiments in electromigrated planar MIM structures, designed with asymmetric plasmonic properties using Au and Pt electrodes. Decay of optically excited local plasmonic modes preferentially creates hot carriers on the Au side of the junction, leading to a clear preferred directionality of the hot electron photocurrent and hence a preferred polarity of the resulting OCPV. In contrast, in an ensemble of symmetric devices constructed from only Au, polarity of the OCPV has no preferred direction.


Deep learning is a sub-set of machine learning practice employing models based on various learning network architectures and algorithms in the field of artificial intelligence. Businesses planning to adopt a deep learning solution should comprehend a set of complex choices in hardware, software, configuration and optimizations to setup a functional deep learning solution. This paper will describe the reference architecture built on Intel Knights Landing processor and omni-path interconnection. We provide a simplified guide to deploy, configure and optimize deep learning solutions based on an array of compute, storage, networking and software components offered by Quanta Cloud Technology. The performance data is presented and it shows good scaling and accuracy on processing the data from IMAGENET.


A projecting piece, which, when a slider butts against a top end stop, presses the top end stop against a tape face and reinforces a projecting portion formed on a main body of the top end stop and the main body, is provided to improve the longitudinal pulling strength of the top end stop. A top end stop (1) is provided to adjoin a fastener element row (5), and a projecting portion (13) is formedon an inner side face (12) of a main body (10) such that the projecting portion projects sideway, so as to form a concave portion (14) in which a flange (27) of a slider (3) invades. A projecting piece (15) thinner than the projecting portion (13) is located in the concave portion (14) such that the projecting piece extends from a contact face (16) of the projecting portion (13) to the inner sideface (12) of the main body (10) in a triangular shape while its front end is inclined. Consequently, the flange (27) presses the top end stop (1) against a tape face by sliding of the slider (3), thetop end stop (1) itself is reinforced, the longitudinal pulling strength is improved, and a step between the main body (10) and the projecting portion (13) is smoothed, whereby a top end stop favorably tactile to the skin is produced.


The September 11 attacks have resulted in immense security concerns in the West, especially in the US. Since then, the US has been involved in the invasion of Afghanistan and Iraq. The terror acts in New York and Washington also shifted the focus of the West on Pakistan. There are concerns in the West on growing militancy in Pakistan, especially in its Federally Administered Tribal Areas (FATA). The West also believes that some extremist elements have infiltrated into Pakistani armed forces and there is a danger of nuclear theft despite having multi-layer protection. The paper discusses the fears in the West about Pakistani madressahs (religious seminaries) as some of them are believed to be churning out terrorists. The paper argues that while apprehensions by the West on a possibility of militants getting control over Pakistani nuclear weapons are unfounded, in fact highly-educated, radicalised terrorists based in the West are the real threat rather than students in Pakistani madressahs. Since America has been active in the Middle East as a major player for the last so many decades, the paper also discusses the follies of the Bush administration in that region. After invading Afghanistan following Sept 11 attacks in 2001 in search of Al Qaeda chief Osama bin Laden and toppling Taliban, US forces were sent to Iraq in search of Weapons of Mass Destruction. These actions increased rancour in the Muslim world, in general, and in the Middle East, in particular. America is a great proponent of democratisation of the Middle East. The US believes that despotic monarchies in the Middle East are a cause of rising terrorism and religious extremism. Although democratisation or bringing reforms in the Middle East cannot be opposed, considering democracy as a source of elimination of terrorism is a misperception. It is generally believed that the US is trying to 'impose' democracy in the Middle East. This 'imposition' of democracy by the US is counter-productive and could have negative fallout in the Muslim world. The crux of the issue is pro-Israel policies adopted by the US, but more serious matter of concern is the 'Israel lobby' in the US which is considered a major factor in shaping the US foreign policy which is mainly considered against the Muslim world. The Palestine and Kashmir issues and the US stand over them is yet another factor for radicalisation as it is causing alienation among the Muslims. The paper advises that for curbing terrorism and religious extremism, the US must have a balanced foreign policy based on sincerity not on deception and political intervention. There must be harmony, inter-faith dialogue and reconciliation between the West and the Muslim world. The so-called 'war on terror' has not produced results; therefore, the US has a greater role to play for a better and safer world.


Recent vehicle speed surveys provide greater detail and accuracy than previously, and suggest a dramatic increase in excessive speeds on UK roads. As vehicles travel faster, the energy required to overcome aerodynamic drag increases approximately exponentially, and becomes the dominant term in total fuel use. The ERR Transport Emissions Model was used to calculate the additional energy consumed, and the potential savings from enforcing or reducing speed limits. The results suggest that 3.1% of car CO2 emissions (0.6 Mt C) could be saved if current speed limits were enforced, or 7% (1.4 Mt C) if a maximum limit of 50 mph were imposed. (A)


commanding the destiny of the Empire.128 This was and is, of course, not just the failing of the Ottoman system but a danger quite common to all empires. Only the incredible richness, accessibility and relative ease of control over the resources which the Ottomans commanded in the Black Sea region and, in general, in its Balkan and Anatolian heartlands, made it possible for the Ottoman Empire to survive the very serious internal and external threats to its viability in the period between the end of the sixteenth century and the Treaty of Kuiguik Kaynarja in 1774. 128 See the standard study on these themes by T. W. Arnold, The Preaching of Islam (Lahore, 1956), especially pp. 1-44, 145-205, 440-46, and P. Wittek, The Rise of the Ottoman Empire (London, 1938), passim. As the Grand Vizier, Sokollu Mehemmed Pasha was reported to have said when faced with the demands of the war party for war against Persia, "Those who propose this project are those who do not know the fatigues of the Persian campaign, [and] who, leaving aside horses and pack animals, do not even ride oxen." Cf. Pegevi, Tarh, II, pp. 36-37.


A 63-year-old woman presented with a complaint of left buttock mass that had rapidly increased in size after a recent trauma. The patient was otherwise asymptomatic, denying any pain or constitutional symptoms. On physical exam, a well-defined, firm, freely mobile 20-cm mass with intact, non-erythematous overlying skin was palpated in the medial-lower quadrant of the left buttock, contiguous to the left perineal region. On digital rectal examination, the mass was palpable on left posterior aspect of the rectal wall, with smooth and intact overlying mucosa.


Nowadays, the development of the automotive industry in Indonesia is increasing followed by high number of motor vehicle theft. In order to reduce the motor vehicle theft case, a Global Positioning System (GPS) based instrument in motor vehicle is investigated to monitor the location of vehicles. This instrument will be run if there are a phone signal from provider and GPS signal from satellite. The method is that the owner sends a text to the destination number installed in the instrument. There are some codes needed to be paired to the instrument. If the code is matched, instrument will reply the text automatically based on the program installed in the instrument. This instrument has many advantages, such as could give the location accurately with an error less than 5 meters, could turn off the vehicle, could give an information if the vehicle is stolen, and also could record the conversations while the vehicles are in use. This instrument is also improved by installing the local language (Indonesian) and features which meet the owner requirements. Generally, it could be concluded that this instrument really helps the rider or owner from motor vehicle theft. Good response and accurate location given by the instrument verified by the finding of lost vehicle showed that this instrument could be applied and important if it is applied in the motor vehicles.


The intact methyl bromide molecule acts directly as an alkylating agent on amino acids and bioactive proteins that contain sulfhydryl groups, leading to a permanent cytotoxic effect. In contrast, bromide ions temporarily displace chlorine ions in neuronal cells that can lead to impaired neurotransmission. Furthermore, blood bromide levels cannot be correlated with severity of methyl bromide symptoms. Deaths have occurred with patients with blood bromide levels as low as 83 mg/L, whereas others suffered only dizziness at 125 mg/L. Comparing bromism with methyl bromide toxicity is therefore not valid and an alternate hypothesis must be considered to explain the anomaly between low bromide levels and reported neurological symptoms.


Sesbania grandiflora is important agro forestry species. These plant species threatened due to habitat destruction, urbanization, forest fire, environment changing and biotic factors. So now it is listed amongst threatened species in many states in the country. Hence, there is an urgent need for conservation of this species. The present study was carried out in Jwala Nagar district Meerut for the period March 2016 to June 2016. A total 100 seeds were sown in 5 cemented pots containing soil, manure 3: 1 ratio. The germination starts 5 days after sowing in the month of March. The total germination percentage were observed 100 % within 21 days during the of 15 March 2016 from date of sowing. Germination percentage, early growth status and root nodule formation period  were recorded at March to June 2016. Three months, (March to May  2016) old saplings were planted into the rural and urban areas  of  Meerut district. Final reading on plant growth status was recorded at 30 June 2016 in field areas of Meerut district. The results indicate that the status of germination, seedling growth and development root nodule period  of all stages fairly rapid. I had recorded March 2016 to June 2016 length and girth size status of S. grandiflora Mean 149.78 cm., 6.96 cm in Meerut areas. It is concluded that the aim of the present study is to spread awareness towards the conservation and established of the threatened tree species Sesbania grandiflora in Meerut district. The study will be benefited to soil improvement, forest management, farmers  and mankind in those areas, where the plant is not found.


The design of LC simulation type active RC filters is well known. The active RC filters using the LC simulation have an inherent low-sensitivity property of the LC ladder filter. Moreover, the circuit parameters of conventional LC ladder filters can be utilized. The LC simulation is realized by using the gyrator. This paper describes the three-port gyrator constructed by using new four-port current conveyors(CFCC II's) and the grounded resistances. The CFCC II is implemented by second-generation current conveyor(CC II) with a current follower. A new multi port gyrator which is obtained by an extension of the three-port gyrator is proposed. As an example, the fifth-order LC ladder low-pass filter(LPF) using the five-port gyrator was realized. The experiment results agree well with the theoretical value. In addition, the dynamic range and the amplitude sensitivity of the LPF were considered. The proposed circuit reduces the influence of the parasitic elements of the current conveyors because all passive elements are grounded.


We consider approximations to the solutions of differential Riccati equations in the context of linear quadratic regulator problems, where the state equation is governed by a multiscale operator. Similarly to elliptic and parabolic problems, standard finite element discretizations perform poorly in this setting unless the grid resolves the fine-scale features of the problem. This results in unfeasible amounts of computation and high memory requirements. In this paper, we demonstrate how the localized orthogonal decomposition method may be used to acquire accurate results also for coarse discretizations, at the low cost of solving a series of small, localized elliptic problems. We prove second-order convergence (except for a logarithmic factor) in the L2operator norm and first-order convergence in the corresponding energy norm. These results are both independent of the multiscale variations in the state equation. In addition, we provide a detailed derivation of the fully discrete matrix-valued equations and show how they can be handled in a low-rank setting for large-scale computations. In connection to this, we also show how to efficiently compute the relevant operator-norm errors. Finally, our theoretical results are validated by several numerical experiments.


The spread of the Corona virus or better known as Covid-19 cannot be estimated when it will end. This condition is very concerning, including Indonesia, which has the highest death toll in Southeast Asia. This virus has also spread in North Sumatra including Deli Serdang Regency. One of the biggest challenges in mitigating Covid-19 is building public awareness about the importance of following the Covid-19 protocol in carrying out daily activities. Unfortunately, this condition is exacerbated by the low level of public awareness by ignoring health protocols during the pandemic period. It is hoped that the role of universities in educating the public can help prevent the spread of Covid-19 and increase community participation in mitigating efforts to prevent its spread. One of them is through community service activities by utilizing traditional ingredients for health drinks which are held at the Villa Mutiara Johor II Complex and its surroundings, Kec. Namorame, Deli Serdang Regency.


Diane Ravitch's (2010) critique of the standardized achievement testing apparatus has not been refuted, but it has been criticized for failing to present an alternative. Likewise, proponents of standardized achievement testing, although conceding, "it has its flaws," respond "there is no better way." This commentary sketches a Plan B alternative that is supported by contemporary events and by Educational R&D resulting from the original Elementary and Secondary Education Act (ESEA) of 1965.


A wireless device (UE1) transmits downlink interference-related information to a transmission point (TP1). The wireless device (UE1) generates this information by listening (604) to reference signals associated with a first reference signal resource (TP1) as well as with a second reference signal resource (TP2). The wireless device (UE1) uses these reference signals to estimate a first channel matrix relating to the first reference signal resource and a second channel matrix relating to the second reference signal resource. Using the estimated first and second channel matrices, the wireless device (UE1) derives (605) a pair of precoding matrices. Precoding matrix indicators representing the precoding matrix pair are sent (606) to the transmission point (TP1).


Abstract An audit of dental health education materials frequently used by community dental services in the North West of England is presented. It identified many improvements to be made in the resources and provided an enjoyable, useful and relevant training session for a variety of oral healthcare workers. This article describes how assessment techniques for dental health materials were applied in an Inter-Trust audit in the North West of England in February 1997. Holloway et al (1997) described such a method of appraising dental health education material. They summarised how resources were assessed for the second edition of the Catalogue of Dental Health Resources for England, Wales and Northern Ireland (Blinkhorn et al 1997).


Introduction This chapter examines a counselling psychology psychotherapy session and reports on how the therapist occasionally produces turns that correct, or more generally offer alternative words for, just-prior expressions produced by the client. These proposals may rephrase something that the client has said in a contrasting way or in a more explicit way. This chapter, in common with other contributions to this book, draws on conversation analysis (CA). Specifically, it draws on CA work on the organization of repair to show that, structurally, some of the corrections used are amongst the stronger forms of repair types that occur in talk. Although such choices might appear unexpected in psychotherapy, the analysis shows how these repair formats are in fact appropriate to certain tasks within the psychotherapeutic session; in particular encouraging the client to talk more explicitly and openly about her feelings (the client in the data I will present is female, and the therapist is male). Two dimensions can be identified in talk that recomposes just-prior talk: a dimension that corrects that prior talk and a dimension that shows an understanding of it. Both these dimensions may be present in the therapist's articulation of alternative ways of saying things: he displays that he is monitoring the client closely, but he also suggests that the client should express her feelings more explicitly. I compare and contrast the use of such proposals with talk that challenges or disagrees with things that the client says.


ABSTRACT Direct cinema's attempt to withhold itself from the world is ethically problematic. The helplessness of documentary subjects and audiences is underscored by this observational style. In Gimme Shelter—a concert film by Albert and David Maysles and Charlotte Zwerin about the Rolling Stones and the fatal violence at the Altamont Speedway Free Festival—social actors are forced to submit to a representational frame they cannot 'see', let alone access. Moreover, the audience's own distance from the pro-filmic events is doubly assured: the film-maker's policy of non-interference precludes and/or renders moot a viewer's impossible desire to intercede on the subjects' behalf.


Waveforms and power spectra of acoustic signals used to elicit the auditory brainstem response were analyzed with respect to electrical and acoustical differences. Signals were of alternating polarity and included a dc pulse, tone bursts of 0.5 and 4.0 kHz, a 4.0‐kHz tone pip, and a 2.0‐kHz logon. The earphone faithfully transduced the temporal dimension of the 5.0‐ms bursts and pips while the logon (450 μs) and the click (100 μs) durations were on the order of ten times greater than the electrical input. Earphone distortion included the loss of well‐defined energy peaks and a spread of energy to higher frequencies. Signal polarity was not maintained through the earphone.


In graph theory connectivity is stated, prevailingly, in terms of paths. While exploiting a proof assistant to check formal reasoning about graphs, we chose to work with an alternative characterization of connectivity: for, within the framework of the underlying set theory, it requires virtually no preparatory notions. We say that a graphs devoid of isolated vertices is connected if no subset of its set of edges, other than the empty set and the set of all edges, is vertex disjoint from its complementary set. Before we can work with this notion smoothly, we must prove that every connected graph has a non-cut vertex, i.e., a vertex whose removal does not disrupt connectivity. This paper presents such a proof in accurate formal terms and copes with hypergraphs to achieve greater generality.


By the visit to some American schools, the observation on science classrooms and a comparative study on the Chinese and American educational system, we find sone big differences in school science education between two the countries, that is the differences of ideas and system of science education, classroom teaching methods of science, science curriculum and teaching resources, science teaching materials and its usage. Knowing and understanding these differences will be helpful for the popularization and development of basic science education and the improvement of science teaching quality.


N2‐fixing bacteria belonging to the genus Raoultella of the family Enterobacteriaceae are widely associated with plants. Raoultella sp. strain L03 was isolated from surface‐sterilized sugarcane roots. In this study, we inoculated the strain L03 to microbe‐free micropropagated plantlets of the main sugarcane cultivar ROC22 grown in Guangxi, China and determined N2‐fixation and association between strain L03 and sugarcane plants. Inoculation of strain L03 increased plant biomass, total N, N concentration and chlorophyll, and relieved N‐deficiency symptoms of plants under an N‐limiting condition. An 15N isotope dilution assay revealed 15N isotope dilution in the inoculated sugarcane plants and incorporation of the fixed 14N from air into chlorophyll. Moreover, a gfp‐tagged and antibiotic‐resistant L03 strain was reisolated from surface‐sterilized sugarcane plants and was detected in plant tissues by fluorescent microscopy. This study for the first time demonstrates that a Raoultella bacterium is able to fix N2 in association with the plant host.


The dynamics of transient plasmas generated by high-fluence nanosecond laser ablation has been investigated by recording the ionic current with a Langmuir probe. Systematic measurements have been carried out on a plasma produced in vacuum by Nd:YAG laser irradiation of a copper target. The temporal evolution of the ionic current for different fluences was investigated, revealing the presence of some periodic oscillations. A theoretical model is proposed in order to describe the nonlinear behavior of the expanding plasma by assuming that the motion curves of the ablated particles are fractals. The behaviors predicted by the proposed theoretical model are in good agreement with the experimental findings.


This comparative historical analysis explores how and why family policies such as parental and maternity leave are made and what drives policymaking since the 1960s; a time of significant social and economic change both in regards to the dramatic increase in the number of women in the workforce, heightened awareness of civil rights issues, and growing strength of the women's movement. The United States and United Kingdom share much in the way of culture, history, politics, and demographics. Further, scholars of the welfare state classify both nations as liberal regimes that provide minimal protections to families for caregiving. But counter to expectations, the US and UK guarantee quite different levels of benefits for families. To explain the divergent trajectory of family policy, I examine the following explanatory factors: the activity and strength of civil society advocacy groups including labor unions and women's organizations; the evolution of gender norms over time; and access women have to governmental agencies and elected officials. Analysis draws on field research, interviews, archival sources, and data collection from governmental and nongovernmental organizations. Analysis suggests that changing gender norms and frameworks have a powerful impact not only on policymaking in this arena, but also on the other variables explored in the study.


1. Permeability of the term human placenta to inulin and mannitol was measured in six normal pregnancies. 2. Bolus and continuous infusion of inulin and mannitol to the mother for 1‐2 h before delivery by Caesarean section achieved steady‐state maternal serum concentrations. Net accumulation of inulin and mannitol in the fetus was measured by the subsequent neonatal urinary excretion. 3. Transplacental clearance was calculated by dividing the net flux by the time‐averaged transplacental concentration gradient. Clearance for inulin was 0.86 +/‐ 0.1 ml min‐1 (mean +/‐ S.E.M.) and for mannitol 7.3 +/‐ 0.8 ml min‐1 (n = 6 in both cases).


Abstract:Mouftah's article explores Egyptian anxieties about ignorance and how the January 2011 uprising brought new urgency to calls for managing it. In post-Mubarak Egypt, literacy activism became a major platform from which to "continue the revolution." Drawing on ethnographic research that observes a national literacy campaign among shipyard workers, Mouftah demonstrates how a particular strand of Islamic reformism makes modern education an indicator of morality, ultimately constraining the revolutionary potential of the literacy movement. Literacy activism offers a crucial lens to observe a major challenge for revolutionary action—the negotiation of recognition among social classes. Through attention to teacher-student interactions, she depicts how workers negotiated the power of the written word to gain respect in their early experiments with writing. This article contributes toward an anthropology of ignorance by revealing the political predicaments that arise out of an Islamic literacy activism that, Mouftah argues, is ultimately counterrevolutionary in its effects.


As part of the Common Agricultural Policy, the European Union offers a complex system of rural development interventions, an increased flexibility, allowing through the Rural Development Plan the design of financial envelope according to the national specificity, based on the principle of subsidiarity, The paper examines, using a comparative analysis based on national data, as well as the statistics provided by Eurostat, how Rural Development Plan and the National Plan for Local Development (funded by the national government) have effectively contributed to the sustainable development of rural areas from Romania, emphasizing some specific aspects of the implementation.


A wireless surface acoustic wave (SAW) transponder system was developed to monitor the temperature of rotating rollers of an electrolytic galvanizing plant. The exact knowledge of this temperature could be an important process parameter used for an in-line quality control of the galvanized sheets. The rollers as well as the transponders are exposed to hot sulfuric acid, and rotate with a maximum tangential velocity of 2 m/s.


According to the importance of hardware implementation of Turbo decoder in practice,an improved Log-MAP decoding algorithm suitable for parallel calculation is proposed. In the decoding process of Turbo codes,when calculating the intermediate parameters,this new algorithm replaces the n-input max* operation with the max operation and correlation function calculation,it is effective in reducing the area of storage,and turbo decoder hardware architectures can be implemented with very low-complexity. The improved algorithm is applied in the CCSDS standard and Wi-MAX standard,the simulation results show that the proposed algorithm reduces the decoding complexity and time-delay,and the BER performance is approximate to Log-MAP algorithm,so it has certain feasibility in the practical application.


We present results of a joint PP- and PS-wave AVO inversion from a multicomponent dataset acquired offshore West Africa. We compare these results with the output of the single, P-wave only, inversion. In both realistic synthetic examples and real data the joint inversion produces a better estimation of the shear impedance reflectivity and of the pseudo Poisson's ratio reflectivity compared with the single inversion.