Abstract 2590 Poster Board II-566 Chronic myelogenous leukemia (CML) is caused by a consistent genetic abnormality, termed the Philadelphia chromosome (Ph). It results in the production of BCR-ABL fusion protein, a constitutively active tyrosine kinase. Imatinib mesylate (IM, Gleevec®), the first generation tyrosine kinase inhibitor (TKI), has revolutionized therapy for CML patients. However, resistance for IM develops in a significant proportion of cases, and is predominantly mediated by single point mutations within the BCR-ABL kinase domain. Second generation TKIs such as dasatinib (Sprycel®) and nilotinib (Tasigna®) represent viable alternatives for IM-resistant or intolerant CML patients. Each mutated BCR-ABL has different sensitivity to those TKIs. Thus, it is significantly important to detect early the existence of BCR-ABL mutations and their specificities in treating Ph+ leukemias. We have developed a novel automated method that has high sensitivity to detect a few copies of mutation sequences that are mixed in many copies of normal sequences. This method consists of PCR amplification step and Tm (melting temperature) analysis step that uses a quenching probe. And we have already shown that this system has clinical efficacy in JAK2V617F mutation that is one of the genetic hallmarks of chronic myeloproliferative diseases. (Tanaka R, et al. Leuk Res, 2008). When a whole blood sample or a purified DNA sample reacts with reagents, PCR and Tm analysis automatically processed in the same tube, and whole procedure finishes in approximately 1 hour. The detection of mutation is extremely accurate because the quenching probe is designed perfectly matched for mutated sequence. As Tm value of mutation sequence is higher than that of normal one, it is easy to detect the existence of mutation from the Tm analysis data. We have constructed the probes for 14 mutations concerned for IM-resistance (M244V, G250E, Q252H, Y253F, Y253H, E255V, E255K, T315I, T315A, F317L, M351T, E355G, F359V, and H396R). Considering the clinical significance of T315I mutation, which renders resistance to all currently available TKIs, we refined this method to higher sensitivity for detecting T315I mutation. First, we analyzed the sensitivity of this system on BCR-ABL. In dilution assays using wt and mutated plasmid, the system reliably quantified the mutation in a population containing as few as 3.0% mutant. Moreover, for T315I setting, we successfully detected as few as 0.3% (30 copies from 10,000 copies) mutations by a higher-sensitive assay. Next, we examined the clinical samples. Each sample was also examined by direct sequencing in comparison to our method. Kinase domain mutations were identified in 24 of the 50 (48%) patients. Our automated analysis was enabled to detect mutations in 19 patients, including p-loop mutations (G250E: n=3; E255K: n= 5), IM-binding domain mutations (T315I: n=10), and an activation-loop mutation (H396R: n=1). And all the positive cases (19 of 19) showed a concordance with the result of direct sequencing. On the other hand, 5 cases were detected just by direct sequencing, but all that cases were out of our setting mutations (Q252E, V379I, S417F, E459K). Impressively, in one case, only higher-sensitivity assay could reveal T315I mutation, although it was detected as a wild type both by direct sequence and our usual method. It suggests that the higher-sensitive system could detect low amount of T315I mutation in the earlier stage of disease. In conclusion, sensitivity of our system (3%) is significantly greater than that of direct sequencing (15 – 25%), and results can be obtained within one hour. By the serial monitoring, it is demonstrated the availability of the higher-sensitive analysis (0.3%) to detect T315I mutation. This rapid and accurate detection of clinically significant mutations enables us to contribute to better clinical practice in treating Ph+ leukemia patients, such as in selecting alternative strategies of IM dose escalation, second generation TKIs, or allogeneic stem cell transplantation. Disclosures: No relevant conflicts of interest to declare.


As educators our primary focus is to scaffold knowledge and concepts so that students are prepared for the future and ultimately the workforce. Due to the rapidly changing digital technological advances there has been debate in education on how we provide the skills and knowledge for students so that they become productive and valued members of society. When our current students are entering the work force many of the jobs that may be available have not yet been developed and this is why the platform of the curriculum area of Digital technology plays such a profound role in preparing our students for the future. The focus of the curriculum is to develop processes that enable students to enhance their problem solving skills and to work collaboratively. This skill based approach is in contrast to a purely knowledge based curriculum. At Rangeville State School I have developed a programme that lays the foundation for prep students to start developing those skills that are emphasised in the curriculum. The intent is then to build on those skills and process and to provide a whole school based programme that will help to enhance opportunities for our older students.


Nine lines, 3 testers and 27 F1 crosses of basmati rice (Oryza sativa L.) mated through Line × Tester mating Design to decipher the extent and nature of correlation between yield and yield contributing characters moreover quality traits were also included in the study. At the end of the experiment and subsequent statistical analysis it was deciphered that grain yield per plant has positive significant correlation with number of effective tillers per plant and hulling recovery which pointed that the number of effective tillers is an important trait that can be targeted as a selection criteria in yield improvement programmes in breeding of Basmati rice moreover quality traits like hulling recovery and milling recovery should also be emphasized specially in long-grained rice.


Fecal samples from 277 goats on eleven
farms in Florida
were examined to determine the prevalence and intensity of the multiple species
of Eimeria that infect goats in this
region. The number of oocysts per gram of feces (OPG) was determined by the
modified McMaster technique. Species identification was done following
sporulation. Eimeria oocysts were
found in 97% of the fecal samples. Goats less than one year of age shed
significantly more oocysts than goats greater than one year of age (P Eimeria spp. were identified. Eimeria arloingi (91%), E. ninakohlyakimovae (82%)
and E. alijevi (79%) were the most prevalent species. Other
species present were E. caprina (60%), E. christenseni (60%), E.
hirci (46%), E. caprovina (29%), E. aspheronica (15%), and E. jolchijevi (9%).


Purpose of the study: The relevance of the study is conditioned by the fact that first-year students find themselves in a completely new and unusual for them social conditions, and very often, the process of adaptation to them is unconstructive. It is important for teachers and psychologists not only to create conditions for the effective development of the adaptive potential of the student's personality, but also the conditions for changing the negative personal characteristics that can cause students dis-adaptation and hinder the effective process of their professionalization and socialization in the future. The article aims to study the features of reflection, selfactualization and creativity of first-year students associated with their socio-psychological maladjustment. Methodology: The leading theoretical method for the study of this problem is the content analysis of scientific works related to the problem of research, allowing a comprehensive analysis of the factors associated with the problem of socio-psychological maladjustment of first-year students. Empirical methods were the study conducting using valid diagnostic techniques corresponding to the purpose of the study, statistical analysis and generalization of the results. Results: The article presents the results of an empirical study of the features of reflection, self-actualization and creativity in socially and psychologically dis-adaptive first year students at the University. It is established that the socio-psychological maladjustment of first-year students can be caused by various factors at the physiological, social and psychological level. Applications of this study: The materials of the article are of practical value for the development of psychological and pedagogical programs aimed at increasing the adaptive potential of students in the process of studying at the University. Novelty/Originality of this study: One of the main factors contributing to the appearance of the socio-psychological maladjustment is the lack of constructive systemic reflection, values, skills and aspirations of the self-actualizing personality, as well as personal and social creativity, motivation for self-improvement, self-realization and self-development, skills of setting and achieving goals, understanding life prospects and the ability to adequately and creatively behave in a situation of uncertainty in social interaction.


In 1957, Mukerjee and his associates isolated a phage specifically lytic for all strains of Vibrio cholerae (Mukerjee et al., 1957). A test based on the use of this group IV cholera-typing phage was subsequently found to provide the most sensitive method of differentiating between the two types of O group I vibrios (Mukerjee, 1963a). In the course of their studies on the phage typing of Vibrio cholerae, biotype El Tor, Basu & Mukerjee (1968) isolated a phage, + H74/64, designated group Vin their phage-typing scheme. It was found to be specifically lytic for all pathogenic El Tor strains; nonpathogenic El Tor strains as well as classical V. cholerae strains were insensitive. This paper presents the results of further detailed studies on the group V El Tor-typing phage.


The work of ancient Greek philosophers is, to say the least, timeless, multifarious and continues to be cited all over the world. Among all issues they highlighted the significance of management and the way in which the State as well as private affairs were organized. This proves that the prevailing view arguing that Management Science is the result of the industrial revolution and especially in Anglo-Saxon countries is not consistent with reality.
In ancient Greece the structure of city-states has proven that an effective management function had been established, and by extension its application to all aspects of public life as well. Xenophon is considered by many the father of Management Science. The Oeconomicus by Xenophon refers to the art of household management, while the definition of management is introduced as well. The Nicomachean Ethics by Aristotle is widely considered a classical work which could be taught today in the Faculties of Management and Economics and particularly emphasizes on ethics, leadership and education. Aristotle laid the foundations of the scientific method and introduced the definition of Science.
Through the Socratic method (maieutics), Socrates is considered the philosopher who established the concept of guidance, and regards management as a special skill, distinct from experience and knowledge.  Plato referred to leadership and general culture as well as issues of ethics.
Many political and military leaders (such as Cleisthenes, Miltiades, Thucydides, Solon and many others) engaged in state affairs management or took the lead in the military sector.
The aim of the proposal under evaluation is to present the classical theories and the way they are incorporated into the modern management of both public and private sector in the era of globalization, multi-culturalism, diversity, electronic government and digital transformation.
The proposal under evaluation has adopted the qualitative research method and specifically the tool of literature review. The aim is the holistic approach and analysis of the subject under research. Through the survey of literature, the researchers wish to present the timeless views on Management Science, as well as form new and modern ideas. For this reason, secondary publications relevant to the subject have been selected, such as the works of ancient Greek philosophers, studies, articles, reports, electronic books, texts from websites, etc.
The conclusions of the proposal under evaluation are particularly significant and, whatever their utilization may be, can substantially contribute to the upgrading of Management Science in Greece. Ideally, these classical works could be taught in University Faculties at both undergraduate and postgraduate level.

JEL Classifications: M00, N01
Key words: Quality Management, Administrative Science, Ethics, Management, Education


Fatwa prohibits surrogacy agreements for the Muslims in Malaysia. The legal stand for non-Muslims is left in silence, whereas surrogacy raises issues concerning women and children that necessitate legal attention. Regulative measures are imminent to regulate issues arising in a surrogate arrangement. Malaysia has yet to report of any surrogacy cases. Thus, this article analyses decided cases from other countries that have gained international attention to synthesize issues arising in surrogacy arrangements. Based on the case study analysis, this article discourses areas that regulation should encroach specifically to safeguard the welfare and safety of women and children.
 Keywords: Surrogacy, Conundrum, Welfare, Fatwa.
eISSN: 2398-4287© 2020. The Authors. Published for AMER ABRA cE-Bsby e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v5iSI3.2569


The movement of 3D avatar is essential in virtual reality game in order to perform natural or emotional movement. Numerous researchers generally focus on movements from input such as: joystick, mouse, and keyboard. Other movement's concepts come from artificial intelligence as part of improving interactivity. This chapter intends to offer a different method of controlling the virtual human characters movement that involves human emotion and haptic sensation known as human haptic emotion. The scheme engages human haptic emotion to control object life movements as a way to enhance simulation closer to reality and be more immersive. The movement of 3D avatar is a feature in virtual reality game which is usually controlled by mouse or keyboard, but recently it is controlled by artificial intelligence built from particular rule (Mocholi et al. 2006).


Web log is the fourth network exchange way following Email, BBS and MSN. Most bloggers began to write blogs with great interest, over time their interest gradually achieves a balance. In order to describe the phenomenon that people's interest in something gradually decays and achieves the balance, we first propose a model and give a rigorous analysis on it. This model describes interested in attenuation, and it reflects that people's interest in something is getting more stable after a long period of time. Our analysis indicates that the arrival-time interval distribution of the model is a mixed distribution with exponential and power-law feature. Secondly, we collect blogs in ScienceNet.cn and present an empirical study of blog arrival-time interval distribution. These empirical results verify the model, providing evidence for a new class of phenomena in human dynamics. The empirical results agree with the analytical result well, obeying an approximately mixed form. In human dynamics there are other distributions, not just power-law distributions. These findings show the variety of human behavior dynamics.


Summary form only given, as follows. Plasma immersion ion implantation (PIII) has a number of advantages over conventional beam-line ion implantation techniques. One of them is the ability to implant "interior" surfaces that are not line-of-sight accessible. The inner surfaces of many industrial components, such as dies, bushings, pipes, and so on are difficult to process and inner surface modification using PIII is both interesting scientifically and commercially. We have proposed a method to improve the impact energy of ions implanted into the interior sidewalls of cylindrical specimens by using an auxiliary electrode having a zero potential. The ion-matrix sheath and the temporal evolution of the plasma sheath in a small cylindrical bore with an auxiliary electrode have been calculated for an auxiliary electrode of a regular radius. In this paper, the effects of the auxiliary electrode radius are discussed. We compute the critical radius of the cylindrical bore when the ion-matrix sheath just overlaps as well as the number of implanted ions. The ion density, flux, dose, energy, energy distribution, and average impact energy are also determined for different radii of the auxiliary electrode by solving Poisson's equation and the equations of ion continuity and motion numerically. Our results provide the theoretical background for the implementation of an auxiliary electrode in a PIII instrument.


This research was conducted at Deli Serdang  from March to June 2015. This study aimed to determine the utilization of Gabus Pasir waste fish meal what can increase the profits of farmers in local ducks laying maintenance business. This survey was conducted at Deli Serdang  from March to June 2015. The method used was survey method with consideration of local ducks laying maintenance studies using Gabus Pasir waste fish meal as substitution of fish meal with farm people in the Desa Lama, Hamparan Perak subdistrict Deli Serdang, with the division of business scale. Methods of data collection is by direct observation and interviews to research utilization of Gabus Pasir waste fish meal with the treatments consisting of: commercial fish meal P 0 (0% : 10%); P 1 (5% : 5%); P 2 (10% : 0%), and farmers consisting of 15 farmers. Respondents were categorised into three scales, scale I (100 up to 300 ducks) consists of 13 farmers, scale II (301 up to 501 ducks) consists of 1 farmer and scale III (502 up to 702 ducks) consists of 2 farmers. The results showed that R / C Ratio in research the utilization of Gabus Pasir waste fish meal with treatment P0 (0%: 10%) were 1,19; P1 (5%: 5%) were 1,22; P2 (10%: 0%) were 1,24, while assuming the utilization of 10% Gabus Pasir waste fish meal with crude protein 16% and a  production capacity of 60% is not feasible. The conclusion is that the utilization of 10% of Gabus Pasir waste fish meal with crude protein 18% more feasible than the crude protein 16% to increase the income of farmers. Keywords : Business Analysis, Gabus Pasir Waste Fish Meal.


The molecular size of type A botulinum toxin affects the response in a time-to-death assay. Definitive statements of specific activity should be based on quantal assay.


The characterization of the water vapor continuum remains an important problem concerning infrared propagation in the atmosphere. Radiometric imaging within the atmosphere in the 8 to 12 micrometers and 3 - 5 micrometers regions, and eye safe lidar in the 2 micrometers and 1.6 micrometers window regions require accurate knowledge of the water vapor continuum. Although the physical nature of the continuum is a complex problem, the observed frequency, pressure and temperature dependence can be represented reasonably well by simple mathematical functions consistent with far wing theories. This approach is the basis for current models used in LOWTRAN/MODTRAN and for the models listed in the SPIE/ERIM EO/IR Systems Handbook (Volume 2 Chapter 1). However, these models are based solely on a limited, but high quality, data set collected by a spectrometer and White cell. Additional information on oxygen broadening and temperature dependence is available from numerous laser measurements of the water vapor continuum. A survey of relevant experimental data is made to determine the best available measurements of the water vapor continuum in various atmospheric window regions. Then the data are fit to an empirical model over the entire window region. A good fit is obtained for typical atmospheric conditions covering the 8 to 12 micrometers and 3 to 5 micrometers regions. No experimental data, covering atmospheric conditions, exist in the 2 micrometers and 1.6 micrometers regions. However, models can be proposed based on far wing extrapolations of the bordering vibrational water vapor bands.


The method of comprehensive study in The Literary Mind and Carving of Dragons is a way to study novels with comprehensive means.It requires the comprehensive awareness to criticize works and the objective and impartial attitude.


Abstract Polycrystalline Pb(Zr0.5Ti0.5)O3 thin films with good ferroelectric properties have been prepared by metallo-organic decomposition (MOD) process, using acetate-based precursors, and followed by two different kinds of annealing process, independently, including oven annealing and rapid thermal annealing (RTA). The experimental procedures were described for the films deposited on Pt-coated silicon substrates. There were distinct differences between oven annealing and RTA process, in terms of structures, morphologies, and electrical properties of the films. The films with RTA process showed denser and smoother surface, finer grain sizes, and much higher dielectric constant (1200–1400), remnant polarization of 30–35 μC/cm2 and lower coercive field of 65–85 kv/cm in the entire annealing temperature range of this study. At an annealing temperature of 550°C, RTA processed films showed identical XRD patterns of perovskite phase and clear ferroelectricity; however, it was not possible to realize the perov...


In this paper, near real-time GPU implementations of two efficient SAR change detection methods using closed-form Kullback-Leibler divergence between generalized Gamma distributions (KL-GGD) and two densities approximated by Edgeworth series (KL-EW) are investigated and compared in terms of both accuracy and speed. The near real-time implementations of the proposed methods using Compute Unified Device Architecture (CUDA) on Graphics Processing Units (GPUs) are described and evaluated. The computation time of the parallel implementation on GPU is compared with the C/C++ implementation on Central Processing Unit (CPU). Our experimental results show that the GPU implementation is at least twenty times faster than the CPU implementation.


This paper describes the various techniques used to reduce the vampire power consumed by electronic devices for domestic applications. A review highlighting the importance of vampire power along with merits and demerits of various techniques used to mitigate the vampire power is dealt in this paper.


The article describes the studies of the level of ethnic tolerance among the students of PFUR. There is a brief description of the applied research instruments on the basis of Bogardus' scale and the index of national distance status. The authors also analyze the data according to the level of ethnic tolerance to various ethnic groups and the changes in the students' tolerance levels in the past four years.


Almost every day of our working lives we become involved in a shopping activity of some kind or another. Going shopping, like cooking and catching buses, has become a habit, and like any habit the sense of deliberateness or selectivity has worn off. Now and again a shopping task takes on an air of urgency, becomes for a few hours something special: that present for a special person or for a special event such as Christmas. A sudden wealth, a sudden craving to indulge in an extravagance, serve for a moment to create an awareness of the problems of making a right judgment. It is on these occasions that we do pause awhile: our eyes cease their flickering appraisal of the mass of merchandise and we see.


Biotechnology is generally considered one of the key technologies of the 21st century, with a potentially wide range of applications in e.g. healthcare, agriculture, and industrial production processes. However, this notion has not yet been substantiated, as the diversity of sectors in which biotechnology is applied makes it difficult to investigate its actual degree of diffusion. Against this background and following a request from the European Parliament, the European Commission initiated the Biotechnology for Europe Study (Bio4EU Study). The study's objectives are to assess the contributions of modern biotechnology to the achievement of major European policy goals, and to increase public awareness and understanding of modern biotechnology. This report presents an analysis of the collected data with a view to assessing the contributions of modern biotechnology to major EU policy goals such as economic growth and job creation (Lisbon Agenda), and environmental sustainability and public health (Sustainable Development Strategy). As such, the study can be considered a background document of the Bio4EU synthesis report, which sets out the main findings of the study. How to obtain EU publications Our priced publications are available from EU Bookshop (http://bookshop.europa.eu), where you can place an order with the sales agent of your choice. The Publications Office has a worldwide network of sales agents. You can obtain their contact details by sending a fax to (352) 29 29-42758. The mission of the JRC is to provide customer-driven scientific and technical support for the conception, development, implementation and monitoring of EU policies. As a service of the European Commission, the JRC functions as a reference centre of science and technology for the Union. Close to the policy-making process, it serves the common interest of the Member States, while being independent of special interests, whether private or national. LF-N A -2313-EN -C


This study applied Analytical Hierachical Process (AHP), a mathematical model for resolving complex systems,  to solve the incessant Boko Haram Crisis in Nigeria. At the core of conflict resolution is the need to assess the benefits and costs of the proposed solutions. AHP which is a model for conflict resolution was used to build a real life model of the Boko Haram Crisis. The model relies soely on the hierarchical structure of AHP which was the basis for the software designed for this work. The most critical point in this work is the determination of the relative priority of the criteria, objectives and alternatives used during the decission making. This research  concludes that for a lasting solution to the incessant Boko Haram Crisis, violent demonstration should be in the direction of dialogue. Dialogue should be centered on Imposition of Sharia Rule and Security as these two objectives have the highest priority with respect to Boko Harm Sect and Federal Government Respectively. Keywords : Analytical Hierarchical Process, Boko Haram, Conflict resolution, Dialogue


Perceptual cognition has been a basic and important factor in human life, in fact for all life in general. It may be regarded as pivotal to mental functions and physical behaviour of human beings and its central and pervasive role needs no special mention. The claim of primacy and significance of perception as a foundational mode of knowing can hardly be a matter of dispute and disagreement as all other modes of knowing like inference seem to originate in perception and find their ultimate validation in perception. It cannot be denied that all cognitive processes in the empirical sphere begin with perception but there may be difference of opinion whether they end up in perception. There can again be no unanimity in regarding empirical perception as the sole variety of perception. In spiritual, mystical, religious and some schools of moral thinking, there has been an acceptance of trans-empirical perception. In fact, there have been claims that this alone is genuine and truly veracious perception. However, as a worldly being, our main concern is with empirical perception, which may be the subject matter of our deliberations, though some references to the trans-empirical may not be ruled out. Without denying the validity of trans-empirical perceptions that are intuitive realizations of a higher type available only to realized souls , it must be pointed out that they are beyond the ken of our thought and language. They are to be experienced and not to be analysed or deliberated upon. The role of perception in cognizing the reality has always been regarded as inevitable and valuable. Through perception alone the reality is said to be directly apprehended.


A satisfactory classification of patients with organic heart disease based on their ability to carry on physical activity would be of great value to every clinician. It is our purpose in this article to show that the consideration of the vital capacity of patients with heart disease, together with their respiratory frequency, pulse rate and systolic blood pressure, after climbing 30 feet of stairs in forty seconds divides them into three main groups. The form of exercise test used in this study differs entirely from that type of test in which the individual is exercised until dyspnea first appears, in that a definite time and weight lifting task is accomplished. In this study the reaction of the individual to a definite task is noted instead of only the amount of work that may be done to bring about dyspnea in the individual. It is hardly necessary to state that the


The National Assessment of Evaluation Progress(NAEP) is currently the only national continuing assessment program which periodically evaluates primary and secondary students' academic achievement in various subject areas in the United States.In recent years,to encourage the students with disabilities to participate in it,NAEP has made some relevant policies and implemented them through providing accommodations and making special decisions,in which it has made good achievements.


A novel control algorithm for an active power conditioner (APC) is proposed. The operation of this APC can be divided into two modes: active power filter mode and back-up power mode. When the mains are normal, the proposed APC operates in the active power filter mode that provides the functions of active power filter and battery charger. Once the mains have failed, the proposed APC operates in the back-up power mode to supply power to the demands. In this circuit design, the control circuit is suitable for both operation modes except in the arrangement of feedback signals. Hence, the design cost can be reduced; also, no load current sensor is used in the circuit. The practicality of the method is, therefore, further enhanced.


Recent technological advances have enabled to use genomic data in livestock evaluation. Single nucleotide polymorphism (SNP) are one of the most widely used genetic markers because they are widely spread along the genome and also could be associated with traits of economic interest. High-throughput panels are becoming interesting for the producers as the cost of genotyping reduces. The objectives of this study were to evaluate the extent of linkage disequilibrium (LD) and the phase of linkage disequilibrium (PLD) between Canchim animals and MA genetic group; and to apply the "Generalized Quasi-Likelihood Score" method to perform a genome wide association study with birth weight (BW), weaning weight (WW), yearling weight (YW), scrotal circumference at weaning (SCW), scrotal circumference at yearling (SCY), age at first calving (AFC), and age at second calving (ASC). Analyses considered 285 Canchim animals (Charolais-Zebu proportion of 62.5% 37.5%) and 114 animals of the MA genetic group (Charolais-Zebu proportion of 65.6% 34.4%) genotyped with the BovineHD Illumina Bead® chip (777k). Two marker densities were used for the LD and PLD analyses; one considered the 777k panel while the other considered a reduced panel which was resulted from a combined information of the high-throughput panel and the BovineSNP50 chip bead v2 map from Illumina®. These analyses were carried out for Canchim, MA, and Canchim + MA animals. PLD conservation was high in both panels, but only the 777k panel had higher mean r (LD measure) equal to 0.38, 0.34, and 0.31 at distances from 0.00 to 0.0025 Mb, 0.0025 to 0.0050 Mb, and 0.0050 to 0.0075 Mb in the Canchim + MA analysis. After this step, genome wide associations were carried out using the Generalized Quasi-Likelihood Score method (GQLS), which considers the logistic regression to associate phenotypic information (treated as a covariate) with the genotype (treated as the response variable). Associations were observed for BW in chromosomes 4 and 9; WW in chromosomes 4, 6, and 11; YW in chromosomes 7, 22, 25, and 27; SCW in chromosomes 20 and 28; SCY in chromosomes 5, 9, 13, 14, 18, and 21; AFC in chromosomes 4 and 27; and ASC in chromosomes 10, 11, and 15. A total of 4, 12, 10, 12, 435, 6, and 4 SNPs were associated with BW, WW, YW, SCW, SCY, AFC, and ASC, respectively. There were observed potential candidate genes for BW and WW (DPP6 dipeptidyl-peptidase 6) and YW (CLEC3B C-type lectin domain family member 3 B). These genes act in the central nervous system development and bone mineralization, respectively. For reproduction traits, there was observed possible candidate genes associated with SCW (SRD5A1 Steroid-5alpha-reductase, alpha polypeptide 1 and NSUN2 NOP2/Sun domain family, member 2) and SCY (TRHR thyrotropin-releasing hormone receptor; PEX2 peroxisomal biogenesis factor 2; and MED30 Mediator complex subunit 30) all involved in hormonal processes. The remaining genes appear to be related to the cellular activity maintenance, ion transport and energy production. After studying the LD and PLD we concluded that high-throughput panels could be used in future studies in order to apply a multi-breed genomic selection in this population to promote advances in the breeding program of Canchim breed. The GQLS method was able to identify chromosomal regions associated with reproduction and growth traits. Our findings suggest that the identified regions could assist the selection process applied by the Canchim's genetic evaluation program.


We present a new integrated tool, DERMA, which allows to measure and assess the time evolution of chronic wounds. A laser triangulation 3D scanner is used to acquire the wound geometry with high precision and to capture an RGB image aligned to the geometry. DERMA provides a single and uniform interface to: manage patient data, 3D scanning of the lesion region, and to perform different kinds of measurements and comparisons: geometric (on the 3D model) and colorimetric (on the image). All acquired data (3D geometries and images) as well as the measures calculated are stored in a database for monitoring the evolution of the skin lesion over time. The tool, developed in collaboration with dermatologists, is now under field evaluation in two dermatological clinics monitoring the evolution of wounds due to different types of skin diseases.


The sections in this article are

Introduction: Application of Nanoparticles for Noncancer Applications
Physiological and Uptake of Particles
Routes of Tissue and Cellular Uptake of Particles
Uptake by Macrophages and Lymphoid Tissues
Mucosal-associated Lymphoid Tissues (MALT)

Routes of Delivery
Oral
Nasal
Pulmonary
Transdermal/Subcutaneous

Drug Delivery
Ocular Delivery
Anatomy of the Eye
Pathology
Drug Delivery
Tolerability
Future Prospects for Nanoparticles in Ocular Delivery

Macrophage-related Diseases
Leishmaniasis
Other Parasitic Infections

Antifungal
Treatment
Drug Delivery Systems

Tuberculosis
Physiology and Pathology
Treatment
Future Prospects

AIDS
Pathology
Treatment
Nanoparticle Delivery Systems
Vaccines and AIDS

Vaccines
Delivery Route

Diabetes
Treatment
Delivery Routes

Conclusions


ABSTRACT A picosecond modulation of interband (IB) resonant light (- 800 nm) by intersubband (ISB) resonant light (-. 7 tm) in n-doped GaAs/A1GaAs quantum wells is demonstrated. Two-color pump-probe measurements are carried out by usingultrashort (— 120 fs) ISB (pump) and lB (probe) light pulses at room temperature. Ultrafast modulation (FWFIM 1.3 ps) ofthe lB light is clearly observed with a low pump pulse energy of about 4 f3/im2. The observed modulation depth is - 8.5% which corresponds to the absorption coefficient change of as large as 1000 cm1. The modulation depth decreases whenthe pump pulse wavelength is detuned from the ISB absorption peak. The modulation dependence on the ISB light pulseenergy is also measured. The carrier relaxation mechanism in high and low excitation conditions is discussed by employinga numerical simulation of the relaxation process of electron—longitudinal optical (LO) phonon system. The results indicatethat the utilization of the intersubband transition is promising for the ultrafast all-optical modulation and switching.Keywords: intersubband transition, ultrafast, all-optical modulation, electron—LO phonon interaction, relaxation process


Honey is valued in Nigeria both as a food and as a folk medicine. However there are growing fears from the consumers about the hygienic quality of honey being purchased from local retail outlets. Regrettably however there is a dearth of information on the microbiological status of such marketed honey in southwestern Nigeria. An attempt to fill this gap is the rationale behind the present study. Microbiological composition of samples of honey marketed in the six states of southwestern Nigeria was assessed. Seven species of heterotrophic fungi and four species of bacteria were isolated. The bacteria species were Klebsiella edwardsii, K. pnuemoniae, Pseudomonas aeruginosa and Staphylococcus aureus. The identified fungi were Cladosporium wernecki, C. herbarum, Cephalosporium sp; Mucor mucedo, Rhizopus rubrum, Trichophyton rubrum, and Scopulariopsis brevicaulis. Two species of pathogenic bacteria were isolated from honey samples: S. aureus in Ogun State and K. pneumoniae in Ekiti State. One pathogenic fungus, Trichophyton rubrum was isolated from Ondo State honey samples. This was the first record of pathogenic micro-organisms in Nigerian honey. This implies that the microbiological quality of honey in retail outlets should be properly monitored as it is an indicator of the hygienic conditions under which the product was processed, handled and stored.


The last decade witnessed drastic increase of excavations of prehistoric sites, to the extent which new data accumulated by the excavations can seriously modify previous explanation about prehistoric culture of North and South Chungcheong Provinces. This paper firstly attempts to overview what the newly accumulated data are like and how they are represented in national history. Analyzing high school history textbook and a couple of popular introductory history books reveals that some prehistoric sites of Chungcheong Provinces seem to be unnecessarily overemphasized on the one hand, and some are not cited despite of their importance, on the other hand. The portion of prehistory in presenting local history of Chungcheong Provinces is a little higher than in national history. However, it is relatively quite low in comparison to Baekje Kingdom's that has been mainly focused in explaining Chungcheong Provinces' past. Considering educating and/or publicizing local history has been developed by support of local self-governments emphasizing their regions' own characteristics, it is necessary to increase the space given to prehistory for overcome limitation of capital-oriented perspectives. Thus, it is expected that the part of prehistory will be enriched in educating and publicizing Chungcheng Provinces' history Enriching education and publication of prehistory will be successful seems to need overcoming three-supremacist's approach in which only something first, oldest, and best is highlighted, and regionalism, and also developing new agenda for explaining prehistoric society and culture.


The writer attempts to present the problems existing in experimental teaching and learning of costume design in order to work out feasible experimental instruction.In accordance with characteristics of the costume design specialty,five forms of opening experiments are designed to foster students' practical skills,with specific steps for management,contents and faculty arrangement.


The Device-to-Device (D2D) communication gaining a lot of attention from researchers for next-generation networks (5G). The main challenge of D2D communication is interference management. In this paper, we investigate the power allocation problem of D2D communication for mitigating the interference. We propose a power allocation scheme for mitigating the interference along with enhancing the overall cell capacity. This scheme is based on the BAT optimization (BA) algorithm. The main aim of the proposed scheme is to allocate the optimal transmit power to the Cellular users (CUs) and D2D users to minimize the interference along with maximizing the channel capacity as well. We have compared our proposed scheme with random based and particle swarm optimization (PSO) based power allocation schemes. The simulation result portrays that our proposed scheme performs better in terms of enhancing the throughput of the cell along with the mitigation of interference.


Xin Jiang Xian, a historical and cultural city, has rich tourism resources and a long history. It is necessary to analyze its tourism resources to make full use of it to develop tourism. The paper uses the SWOT qualitative analysis and the AHP quantitative analysis to evaluate the tourism resources in Xin Jiang Xian,realizing the combination of qualitative and quantitative. Xin Jiang Xian should take the development of pioneering strategies. Based on the analysis, it puts forward suggestions to develop tourism in Xin Jiang Xian: use the government dominant function, exploit and utilize the resources reasonably, increase the investment in tourism, make full use of media propaganda, construct related facilities and create a special tourism brand.


Neuroblastoma is a strongly heterogeneous cancer with very diverse clinical courses that may vary from spontaneous regression to fatal progression; an accurate patient's risk estimation at diagnosis is essential to design appropriate tumor treatment strategies. Neuroblastoma is a paradigm disease where different diagnostic and prognostic endpoints should be predicted from common molecular and clinical information, with increasing complexity, as shown in the FDA MAQC-II study. Here we introduce the novel multiobjective deep learning architecture CDRP (Concatenated Diagnostic Relapse Prognostic) composed by 8 layers to obtain a combined diagnostic and prognostic prediction from high-throughput transcriptomics data. Two distinct loss functions are optimized for the Event Free Survival (EFS) and Overall Survival (OS) prognosis, respectively. We use the High-Risk (HR) diagnostic information as an additional input generated by an autoencoder embedding. The latter is used as network regulariser, based on a clinical algorithm commonly adopted for stratifying patients from cancer stage, age at insurgence of disease, and MYCN, the specific molecular marker. The architecture was applied to Illumina HiSeq2000 RNA-Seq for 498 neuroblastoma patients (176 at high risk) from the Sequencing Quality Control (SEQC) study, obtaining state-of-art on the diagnostic endpoint and improving prediction of prognosis over the HR cohort.


Graded readers are a much misunderstood breed. Most teachers understand that graded readers are simplified books written at varying levels of difficulty for second language learners. They also know that graded readers cover a huge range of genres ranging from adaptations of classic works of literature to original stories, to factual materials such as biographies, reports and so on. Teachers are also aware that graded readers are written for many different audiences, ages and difficulty levels. However, not all teachers have a clear idea of their function and how they fit the curriculum and misinformation abounds. This article is in two parts. The first part discusses what graded readers are and provides many reasons why they are important in learning foreign languages. This section also reviews many of the issues and controversies that surround the use of graded readers and suggests that graded readers are an essential part of any curriculum. The second part of this article discusses many of the points that need to be considered when writing a graded reader.


Objective To investigate the changes of circulaling progenitor cells and endothelial progenitor cells(EPCs)in non-septic and septic shock patients using flow cytometry.Method A total of 27 sepsis patients hospitalized in emergency department of Zhongshan hospital during August 2007 to February 2008 were enrolled in this study.The patients were dividedinto septic shock group(n=12)and non-septic shock group(n=15).Ten healthy individuals and ten non-sepsis ICU patients were collected as controls.Peripheral blood mononuclear cells(PBMCs) were isolated by Ficoll density gradient centrifugation,and EPCs labelled with antibodies against CDl33,CD34 and VEGFR-2 were identified and isolated by three-color fluorescence flow cytometry.Differences within the groups were analyzed using One way ANOVA.Results The percentages ofprogenitor cells and EPCs in the PBMC fraction in healthy controls were(0.25%4-0.14%),(0.09%-I-0.02%),respectively,and those in ICU controls were(O.38%.4-0.29%),(0.12%.4-0.02%).The percentages of progenitor cells and EPCs were significantly higher in栅sel如c shock patients(0.57%±0.12%),(0.22%.4-0.10%)than in heathy and non-sepsis ICU controls(P<0.05).However.the percentages of progenitor cells and EPC8 in septic shock pa.tienta(O.20%±0.12%,0.04%-t-O.01%)was obviousely lower than those in healthy,ICU controls and ilionseptic shock patients(P<0.05).Sptic shock survivors had significantly higher numbers of cEPCs than nonsur.vivors(P<0.05).Conclusions The level of progenitor cells and EPC8 in peipheral blood of sepsis patients might be the valuable markers to as.se88 the severity and outcome ofthese ptienS.

Key words:
Sepsis; Sepsis shock progenitor cell; Endothelial progenitor cell; Peripher blood


rd based learning is not offered for 2 year and only 3% for 3 year in the curriculum .The other teaching strategies are falling in between lectures and PBL. In terms of students learning needs a substantial gap was found between learning styles' and the teaching strategies offered. CONCLUSION: It is the need in time to bring reform in teaching strategies with a student centered approach in the light of new trends worldwide. This would embrace our students to learn how to learn and be self directed life long learners.


After the aplication of the PRECAVES XXI survey, we checked that the future granadan Spanish teachers show a grade of identification of the varieties that oscillate between the good identification (varieties from Rio de la Plata, Castilian and Andalucian), medium identification (Canarian, Caribean, Mexican and Andean) and bad identification (Chilean). We verified the tendency to establish hierarchies between varieties, in this case in favor of the Castillian. Additionally, the direct valuations point us that the Castillian variety has a special treatment than the others, because it has a better cognitive consideration (is considered urban and clear), but it has the worst afective consideration because it is considered distant, ugly and boring. The indirect valuations of the Andalucian varieties show a strong grade of stigmatisation, specially in the socieconomic valuation. There is also an American variety badly valued: the Andean. We suppose that a discriminatory reaction towards the immigrant communities from that origin is reflexed.


This research aimed to evaluate the antimicrobial effectiveness of a disinfectant (Lysol) for dental use in the spittoons of the dental units of the school of Dentistry of Universidad Nacional de Chimborazo. A sample of 20 spittoons was taken for microbiological analysis, these ones were obtained with sterile swabs both before and after applying the disinfectant, they remained in incubation for 48 hours at 37 ° C for the development of microorganisms. The first planting was performed by sowing the same sample in bipetri boxes containing blood agar and nutritive agar in order to determine the contamination of them. After planting the boxes remained in incubation at the same time and at the same temperature as the samples, giving as result of 100% growth of microorganisms in the samples taken before the application of the disinfectant and 25% growth of microorganisms after applying the disinfectant, it meant a reduction of 75% of microorganisms after the effect of the disinfectant. S. aureus was identified as the most frequent microorganism with presence in 40% of the total sample. Finally, it was concluded under the biological indicator that Lysol is a medium effectiveness disinfectant, which significantly reduces the contamination existing in spittoons, but it does not eliminate all microorganisms completely.


This article reviews the recent literature on directed systemic tumor therapy based on antagonists of gonadotropin-releasing hormone (GnRH) and growth hormone-releasing hormone (GHRH) as well as analogs of GnRH as carriers for chemotherapeutic agents. Human breast cancer is known to express receptors for GnRH and GHRH in 50% and 35% of the cases, respectively. The expression and the growth-stimulating effect of GnRH and GHRH ligands have been previously described for breast cancer. Thus, targeted therapy with antagonistic analogs of these peptide hormones is a promising option in this tumor entity. Alternatively, GnRH receptors on breast cancer cells can be used as target structures for cytotoxic hybrid molecules comprising an agonistic analog of GnRH and a cytotoxic radical. This therapeutic approach aims at achieving a higher concentration of the cytotoxic radical in the vicinity of the tumor, thus maximizing antitumor effects and minimizing unwanted side effects. The recent preclinical and clinical data on this subject are reviewed.


This article summarizes details of an instrumentation system for continuous measurement of environmental
parameters in poultry and swine facilities. The system simultaneously measures temperatures, relative humidity, ammonia,
carbon monoxide, oxygen, and hydrogen sulfide levels in two buildings. It also measures the operating status of ventilation
fans for each building. Other measurements include: carbon dioxide in one building, solar radiation, outside temperature,
and outside relative humidity. The components described and the experiences gained over a six–year period of monitoring
in commercial animal facilities may be helpful to others considering continuous environmental monitoring.


BACKGROUND
In the last decade, application of the high-definition exoscope to different neurosurgical procedures has been reported in the literature. We describe the first experience with the VITOM®-3D for the surgical treatment of intradural extra-medullary tumors.

METHODS
Five neurosurgical procedures for the removal of intradural extra-medullary tumors were performed with the VITOM®-3D. Patients' population, feasibility of surgery under the exoscope visualization, VITOM®-3D's technical and optical characteristics, and surgical outcome were analyzed.

RESULTS
All surgeries were performed following the common steps of spinal neurosurgical intradural procedures. The exoscope offered excellent, magnified and brilliantly illuminated high definition images of the surgical field in all the described cases. All the reported surgical operations were successfully completed under exoscope magnification from both the technical as well as the clinical points of view. No complications potentially related to the use of the exoscope occurred. Working environment ergonomics and trainees learning experience were the most relevant benefits associated with the use of exoscope.

CONCLUSIONS
VITOM®-3D may represent a valid visualization tool in spinal procedure for intradural extra-medullary tumors. Our preliminary experience can be useful in better define the role of VITOM®-3D in neurosurgery.


Most of previous researches investigated the use of Letterland method in teaching English. However, only few researches concern with the Letterland book that have many differences with local story books in Indonesia. This research was aimed to find out how the quality of Letterland book refers to listening, reading, and vocabulary skills, language content (topic, subject content and social and culture values) and the effectiveness of Letterland book. Content analysis method was applied in this research. There were two instruments which are used in this reseach, they are : document and interview that involved teachers in Star Kiddy Preschool and Learning Center. This research used Cunningsworth theory as guidance to analyse the quality of Letterland book. The findings showed that listening, reading, vocabulary skills in Letterland book are categorized as good book. The language contents of Letterland book is qualified as good EFL book criteria. Teachers in Star Kiddy Preschool Star Kiddy Preschool and Learning Center stated that Letterland book is effective to learn English for children. However, there were problems in the implementation of Letterland book such as: limited time, new teachers that had not expert on Letterland book. Therefore, this research was expected to be the an overview of teachers that learnt English by using Letterland book for children.


L t ' Observations are given relating to the. biology, post-embryonic ^development and reproductive behaviour of 'Antrocephalus hakonensis (Ashmead),. a pupal parasi toid of Opisina arenosella Walker, the black-headed caterpilliar pest of coconut.' The adult, before its escape from the host pupa emerges from its own pupal covering. In the laboratory, adult females," when fed; on 50%: honey, lived for a maximum of 90 days while the males survived only for 46 days.: o Copulation was preceded by specific courtship displays. For oviposition,' the. females accepted both naked .pupae as well as those within the cocoon, inside the galleries, .of the host; younger pupae however were "preferred by the parasite. A female lays only one' egg at each act of oviposition, with an average of three eggs per day.


In previous work we showed that programed cell death (PCD) in thymocytes is mediated by a sustained increase in cytosolic Ca2+ concentration, resulting in the activation of an endogenous endonuclease, DNA fragmentation, and cell death. In this study we investigated the roles of Ca2+ and DNA fragmentation in target cell killing by natural killer (NK) cells. The effector cells induced a rapid, sustained increase in cytosolic Ca2+ concentration in Jurkat target cells. Buffering the target cell cytosolic Ca2+ with the Ca2+‐selective dye, quin‐2, prevented target cell killing. Extensive DNA fragmentation was associated with killing in every target tested, and this response was also blocked by quin‐2. The endonuclease inhibitor, aurintricarboxylic acid, inhibited both DNA fragmentation and killing without influencing the Ca2+ increase in target cells. Thus, it is concluded that NK cell killing depends on a Ca2+ increase and appears to involve endogenous endonuclease activation in target cells.— McConkev. D. J.; Chow, S. C.; Orrenius, S.; Jondal, M. NK cell‐induced cytotoxicity is dependent on a Ca2+ increase in the target. FASEB J. 4: 2661‐2664; 1990.


The phosphoramidites 6b and 9 as well as the phosphonate 6a derived from 7-(hex-1-ynyl)- and 7-[5-(trifluoroacetamido)pent-1-ynyl]-substituted 7-deaza-2′-deoxyguanosines 1 and 10, respectively, were prepared (Scheme 1). They were employed in solid-phase oligodeoxynucleotide synthesis of the alternating octamers d(hxy7c7G-C)4 (12), d(C-hxy7c7G)4 (13), and d(npey 7c7G-C)4 (15) as well as of other oligonucleotides (see 22–25; Table 2; hxy = hex-1-ynyl, npey = 5-aminopent-1-ynyl). The Tm values and the thermodynamic data of duplex formation were determined and correlated with the major-groove modification of the DNA fragments. A hexynyl side chain introduced into the 7-position of a 7-deazaguanine residue (see 1) was found to fit into the major groove without any protrusion. The incorporation of the (5-aminopent-1-ynyl)-modified 7-deaza-2′-deoxyguanosine 2 into single-stranded oligomers of the type 24 and 25 did not lead to change in duplex stability compared to the parent oligonucleotides. The self-complementary oligomer 15 with alternating npey7c7Gd (2) and dC units did not lead to a cooperative melting, either due to orientational disorder or interaction of the 5-aminopent-1-ynyl moiety with a base or with phosphate residues nearby or on the opposite strand.


turns the very idea of man. No longer an academic debate, the pro and con of this argument mark the division between the two worlds locked in life-and-death struggle. In the Soviet Union, for the first time in history, the proposition that there is no God, no human soul, no Creation, no moral order, has constituted itself into an official dogma. The denial of God is the premise of public law, public policy, and publicly approved personal conduct. What de Vries, among others, proves is that the Western concepts of man, mind, soul, truth, rationality, development, together with the entire structure of public institutions based on them, are inescapably anchored in the assumption of a divine ground and divine end of being.


An efficient method is presented for optimum design of plate structures where the design variables can be continuous or discrete. The design variables are sizing variables as well as shape variables. A penalty function is used to achieve the discrete solution. Analytical relations are derived for the initial penalty multipliers. The discrete variable optimization is carried out after the completion of the continuous solution. In both the continuous and discrete optimizations all the structural responses such as forces and displacements are approximated as functions of some intermediate variables. Thus the number of structural analyses is reduced during the optimization process. A number of examples are offered to demonstrate the efficiency of the proposed technique.


This book is divided into two parts. The first part is about non-redundant clustering and feature selection for high dimensional data. The second part is on applying learning techniques to lung tumor image-guided radiotherapy. In the first part, a new clustering paradigm is investigated for exploratory data analysis: find all non-redundant clustering views of the data. Also a feature selection method is developed based on the popular transformation approach: principal component analysis (PCA). In the second part, machine learning algorithms are designed to aid lung tumor image-guided radiotherapy (IGRT). Specifically, intensive studies are preformed for gating and for directly tracking the tumor. For gating, two methods are developed: (1) an ensemble of templates where the representative templates are selected by Gaussian mixture clustering, and (2) a support vector machine (SVM) classifier with radial basis kernels. For the tracking problem, a multiple- template matching method is explored to capture the varying tumor appearance throughout the different phases of the breathing cycle.


There are three temporal cycles which have been partially relaxed in urban entities, namely days/nights, weekdays/weekends and winter/summer. They may be examined in light of three pairs of terms: timing/spacing; temporality/spatiality; and temporalization/spatialization. The blurring of the three cycles is differentially related to technological innovations, social change and to the capitalist system. The daily cycle has initially changed by lighting which permitted working, consuming, and transit at night. Weekends, which have emerged as of the late nineteenth century as leisure time units, make more people work through them. Seasonal differences have little impact on modem cities, given the use of air-conditioning and heating. The introduction of zoning permitted continuous time use in selected areas in cities, so that spatial change as a result of temporal ones is limited to selected sites and areas within cities. Private transportation permits an easy move over space from one time mode to another. Time use and space use are interrelated despite the growing decycling of time and the reorganization of urban space.


Australia's social, economic and political order continues to undergo fundamental change. Since the 1980s, the benefits of globalisation and associated micro-economic reforms have dominated the public agenda and continue to generate contentious debate.! In particular, the deregulation of Australia's product and labour markets, alongside the increased emphasis on competition and the dismantling of the welfare state, are subject to critical analysis. Within the labour market the increasing wage and income inequality, the growth in relative poverty, the increased use of flexible employment contracts (part-time, temporary, casual and selfemployment) and the persistently high levels of unemployment have been noted as particularly alarming.2 Concerns have also been raised in relation to the restrictions placed upon people's access to government-provided income support through social security, particularly within a labour market characterised by job insecurity and irregular income} While such changes have had profound implications for both women and men, this paper argues that the patriarchal context within which globalisation, labour market deregulation and welfare reforms occur exacerbates the economic, social and political vulnerability of many women. Given this predicament, the case for further deregulation of the labour market is far from compelling, in fact from a feminist perspective, the argument in favour of competitive labour markets is virtually non-existent. Using feminist economic and social framings, this paper explores the consequences of deregulation as they affect women's participation in the Australian labour market and the parallel relationship with women's access to social security. Beginning with a brief overview of


metal-oxide-silicon tunneling diodes on Si Eih-Zhe Liang, IVir-Ping Hirang, and TingWien Sir Gradirate Instititte of Electro-Optical Engineering Hsing-Hug Hsieh, and Ching-Fuh Lin' Grndiiate Institute of Electronics Engineering * also with Departn~ent ofElectrical Engineering and Gradirate Institirte ofElectro-Optical Engineering National Taiuzan University Taipei 106. Taiwan ROC Tel: 886-2-23635251 ext. 339/Far: 886-2-23638247 Email: cflinCOcc.cc.nhi.edu.tw Si is the most important material for electronics. Due to the mature fabrication-technology based on Si; it is also highly desired to use Si for optoelectronics. In addition, using Si for light sources could provide optical interconnect between 1Cs for fast data transfer [ l ] and support photonic circuihy for direct optical signal processing, based on Si. [2] However, Si is an indirect bandgap material, so light emission from Si is very difficult. In this work, we report the methods to overcome the indirect-bandgap difficulty. Very efficient electroluminescence (EL) at Si bandgap energy is achieved from metal-oxide-silicon (MOS) tunneling diodes on n-type Si. The external quantum efficiency could be 1.5 x IOJ at the injection current of 20 mA. Also, nearly lasing phenomena are even observed. Due to the indirect-bandgap nature of Si, electrons and holes cannot directly recombine. As a result, both phonon and exciton (or electron-hole pair) are involved in the radiative recombination. [3] In addition, the nonradiative recombination ( l i e Sbocklep Rea& Hall (SHR) recombination) usually dominates over radiative recombination. They all need to be taken care for efficient EL om MOS tunneling diode on Si. . To enhance phonon and exciton involvement, confmement of electrons and holes in nano-structures is of great help. This is achieved by replacing the traditional oxide layer by S i 6 nanoparticles (diameter 12 nm), which give a nonuniform oxide layer. Then hole tunnel through the thin region of oxide more easily than the thick region. In addition, band bending toward the SiiSiO, interface causes three-dimensional confinement of electron accumulation. As a result, electrons and holes are confined spatially within a nano-structure. Therefore excitons or electron-hole pairs are more easily formed than the bulk Si. This makes the phonon involvement much simpler because the process is like twoparticle collision instead of three-particle collision. Experiments show that the nano-shuctures in the oxide layer could enhance radiative recombination rate to close to SRH recombination rate, confirmed by carrier lifetime measurement. The carrier lifetime could be reduced from 60 us to 20 us as radiative recombination occurs. On the other hand, the SRH recombination lifetime is still around IO us to 60 us, depending on the quality of the Si wafer or Si surface. Because the Si wafer grown by the float-zone technique could have the carrier lifetime near Ims inside the material, the nonradiative recombination rate could be possibly reduced to about IO'kecond. This gives the opportunity of enhancing radiative recombination to much larger than nonradiative recombination. We use KOH solution to improve the surface quality of Si. Experiments show that the KOH etching (45% weight solution at 50°C) on Si wafer for 20 seconds could increase the EL intensity for more than IO times. The L-1 curve shows that the EL quantum efficiency rapidly increases and reaches 1.5 x IOJ for operation current between 20 mA to 30 mA, then slightly drops to IOJ due to heating effect. EL power could he I O uW at the injection cunent of 100 mA (equal to current density 12.7A/cm?). This power is measured only from the periphery of the Ag-paint pad. If total EL is included, the EL quantum efficiency might exceed IO". Nearly lasing phenomena like threshold behavior and resonance modes are also observed. The operation lifetime test shows that the EL intensity increases for the first few days and then decreases. Because those devices do not have thermally grown oxide, native oxide gradually forms. However, no matter if those devices were exposed to the air or in vacuum, similar EL behaviors were observed. The possible reason is that those SiO, nanoparticles have SiOH bonding on the surface, which assists the formation of SiO, on Si surface. In the first few days after the devices were made, interface states were reduced, so SRH recombination was .reduced. However, oxide formed in such a way is not strong. After long operation, this oxide breaks down and leads to the direct contact of metal and the Si. Then there is no electron accumulation and carrier confinement is eliminated for those regions, so the total EL is reduced. The measured 1-V curves show that the reverse-biased current could increase for ten times after several days, indicating the degradation of the oxide. Well passivation of the Si surface should increase the EL intensity and the operation lifetime. The possibility of efficient EL from MOS tunneling diodes gives the great promise of optical interconnect among ULSl chips based fnlly on the CMOS technology.


The purpose of this study the first is to find out about the current English reading learning. Second, knowing the pattern of learning to read English through metacognitive strategies in the industrial era 4.0. The method used in this study is descriptive qualitative method. Data analysis uses Miles and Huberman theory, namely data reduction, data presentation, and conclusion . The results of this study are, first, learning to read English at this time requires appropriate strategies and appropriate to the needs or the world of work, one of them is the use of metacognitive strategies. Secondly, in the digital era and experiencing acceleration now the learning pattern of reading English texts needs to be done continuously because in the digital era requires good and appropriate reading skills in accordance with the understanding of text content, metacognitive strategies are one solution to overcome reading problems in the industrial era.


The aim of experiment was to investigate the effects of Zhuangjin XuGu decoction (ZJXG decoction) on growth hormone (GH) serum and GH receptor (GHR) expression in callus. The femur fracture animal models were generated in 72 Wistar rats by cutting femur transversely at the middle point. The rats models were administered orally ZJXG decoction for 28 days. Anatomy, X-ray and hematoxylin- eosin (HE) staining were used to observe the healing process in rats. The expression of growth hormone receptor (GHR) in fibroblasts and osteoblasts in callus was evaluated by immunohistochemical assay (IHC). The serum level of GH was passed by enzyme linked immunosorbent assay (ELISA). Anatomy, X-ray and H-E staining indicated that the fibrous callus at the fracture-end increased and the fibrous granular tissue changed gradually to fibrous, cartilaginous and osseous callus. IHC and ELISA showed that after 28 days of ZJXG Decoction treatment, that GH in the fibroblasts and osteoblasts of callus and their serum level increased significantly. These results suggested that ZJXG decoction could enhance the fracture healing by enhancing GH activity and promoting the expression of GHR in the fibroblasts and osteoblasts of callus in rats.


Digital remediation increasingly plays a pivotal role in delivering political messages. This study examines postings of corporeally mediated tattoos in a China-based blog, focusing on in what sense blogs can provide a breathing or even emancipating space for Chinese tattoo wearers and enthusiasts to control the viewer's perceptions of tattooing and negotiate long-standing stigmatized associations of tattoos there. The study analyzes 305 postings collected from the blog covering a period between 24 April 2020 and 3 May 2021, taking a quantitative approach. Methodologically, it first analyses the distribution of the signs across body parts as displayed. By applying multimodal perspectives, this study also investigates photographic techniques such as distance, angle, gaze, and modality harnessed and exploited for visual manipulation during digital remediation of turning body narratives into digital narratives. Findings of the study suggest that digital remediation facilitates personal expression of tattoo wearers and photographic techniques play a critical role in introducing ready alignment of the viewer with the postings. The study thus adds quantitative inquiries to existing, mostly qualitative, studies of tattoos which usually rest on interviews with tattoo wearers, enthusiasts, and artists for an account of tattoo narratives in connection to personal expression and self-definition. Its findings would be inspiring to socially stigmatized and marginalized groups to circumvent social, cultural, and political barriers to communicate and make their stories heard to more people.


High curvature carbon-supported isolated NiN4 sites with ideal CO2 reduction reaction performance were obtained through a top-down strategy. The charge polarization induced by the axial asymmetry of the carbon substrate can enhance the adsorption of COOH* and reduce the free energy barrier of the rate-determining step.


In this paper we introduce the notion of pseudo-ternary semiring. Furthermore, we will introduce pseudo-ternary subsemiring and ideals in pseudo-ternary semiring. Finally, ideals in pseudo-ternary semiring will be used for constructing pseudo-ternary factor semiring.


The drying kinetics of thyme was analyzed by considering different conditions: air temperature of between 40 ℃ and 70 ℃, and air velocity of 1 m/s. A theoretical diffusion model and eight different empirical models were fitted to the experimental data. From the theoretical model application, the effective diffusivity per unit area of the thyme was estimated (between 3.68 × 10−5 and 2.12 × 10 −4 s−1). The temperature dependence of the effective diffusivity was described by the Arrhenius relationship with activation energy of 49.42 kJ/mol. Eight different empirical models were fitted to the experimental data. Additionally, the dependence of the parameters of each model on the drying temperature was determined, obtaining equations that allow estimating the evolution of the moisture content at any temperature in the established range. Furthermore, artificial neural networks were developed and compared with the theoretical and empirical models using the percentage of the relative errors and the explained variance. The artificial neural networks were found to be more accurate predictors of moisture evolution with VAR ≥ 99.3% and ER ≤ 8.7%.


Objective To investigate the methods and efficiency of treatmemt for recurrent epithelial ablasion.Methods 12 cases(12 eyes)were divided into three groups by degree and treatmemt efficacy,according to the analysis of them.They were treated by drugtherapy,mechanical denuding of the loose corneal epithelium and wearing therapeutic soft contact lenses.Results 1 case was cured by drugtherapy.8 cases were cured by drugtherapy and mechanical denuding of the loose corneal epithelium,and 3 cases were cured by drugtherapy,mechanical denuding of the loose corneal epithelium and wearing therapeutic soft contact lenses.Conclusion Diagnosis and appropriate therapy of recurrent epithelial ablasion were the keys to prevent recurrent.

Key words:
Epithelial ablasion, recurrent; Treatmemt; Contact lenses, soft


We investigate a way of mapping bose-fermi systems within the framework of the fermion SU(3) model, using sdg-bosons with intrinsic spin and isospin. Consequences of the formalism chosen are discussed, particularly with respect to a choice of single particle transfer operator for supersymmetry models.


The overseas metallurgical construction projects usually have a greater risk.A set of index system of risk was established,take the case of the NTS500 000 t procject in Thailand.And then have a quantitative research of the projects in the whole risks in the method of AHP.


Double Hung windows are in vogue these days but that doesn't mean you have to just go out and buy them. You need to know about them first so that you ...


Objective. To assess a susceptibility to antibiotic combinations in nosocomial carbapenemaseproducing Klebsiella pneumoniae , Pseudomonas aeruginosa and Acinetobacter baumannii isolates using a modified method of multiple combination bactericidal testing (MCBT). Materials and мethods. A total of 178 isolates (63 K. pneumoniae isolates, 31 P. aeruginosa isolates, 84 A. baumannii isolates) obtained in the 20132017 from hospitalized patients in 28 public health organizations in 4 Belarus regions were included in the study. All isolates were producers of the different carbapenemases (OXA48, KPC, NDM, VIM, OXA23, and OXA40). The susceptibility to antimicrobial agents was determined by an automated method and a broth microdilution method. A modified MCBT method was used for determination of susceptibility to antibiotic combinations. Antibiotic concentrations corresponding to the threshold pharmacokinetic/pharmacodynamics (PK/PD) concentrations for standard doses of antimicrobial agents were used for testing antibiotic combinations. A total of 11 primary and 11 additional antibiotic combinations were tested. Results. The meropenem MIC values were 4 or more times higher than the threshold PK/PD concentrations for most isolates studied. A total of 42.9% of K. pneumoniae strains, 51.6% of P. aeruginosa strains and 2.4% of A. baumannii strains were nonsusceptible to colistin. Using the modified MCBT method, antibiotic combinations with bactericidal activity were detected for 177 (99.4%) isolates; 3 or more antibiotic combinations were bactericidal for 155 isolates (87.1%). The colistincontaining combinations were the most active, including against isolates with colistin MIC values above the threshold PK/PD concentration. The bactericidal activity of meropenem + amikacin and amikacin + levofloxacin combinations against 51.9% of K. pneumoniae colistinresistant isolates was determined. The meropenem + colistin (85.7%) and imipenem + colistin (84.1%) combinations were the most active against P. aeruginosa . All the colistin containing combinations were bactericidal against nearly 100% of A. baumannii isolates. Conclusions. Specieslevel and strainlevel specificity of bactericidal activity for the different antibiotic combinations was found.


Analyses of free amino acids in the juices of an extensive variety of common vegetables is summarized and new data for selected herbs and vegetables is presented. The twenty amino acids needed for protein synthesis are found in amounts significant for vegetarian diets and relevant to the historical development of human beings and our food system. The results provide a nutritionally diverse and significant set of criteria for the selection of crop plant cultivars. The development of mixtures of fruits, vegetables and seeds to achieve a balanced "all 20" presages a transformative cuisine. It is based on the old crops and the new combinations implied by the amino acid analyses and the Genetic Code.


This paper presents a method for users to control their home and office appliances remotely using a mobile phone. This is borne out of the desire to minimise accidents and prevent damage to electrical appliances as a result of not switching off electrical appliances such as pressing iron, electric heater, etc, which can result in fire incidence and damage. The system provides the ease of turning on/off electrical appliances with its attendant safety. The access control is achieved by sending a DTMF code from the user mobile phone to the device mobile phone receiver. The received DTMF code is then decoded by the DTMF decoder which interfaces with a PIC Microcontroller to process the signal and control the appliance with the aid of a relay. The switching system presented in this paper will enable the switching of electrical appliances with AC load of 220V±5% supply from a mobile phone by simply issuing a command through the phone's keypad to the system. This saves time used in switching ON or OFF the electrical appliances manually since the electrical appliance can be controlled from this remote system.


One of the deficiencies of SQL is the lack of support for analytic calculations like moving averages, cumulative sums, ranking, percentile and lead and lag which are critical for OLAP applications. These functions work on ordered sets of data. Expressing these functions in current SQL is not elegant, requires self-joins and is difficult to optimize. To address this issue, Oracle has introduced SQL extensions called Analytic functions in Oracle8 i Release 2. In this paper we discuss the motivation behind these functions, their structure and semantics, their usage for answering reasonably complex business questions and various algorithms for their optimization and execution in the RDBMS server. Several implementation techniques are discussed in the paper. It presents heuristic algorithms used in the optimizer for reducing the number of sorts required by multiple Analytic functions. It also covers specialized processing of Top-N Rank queries to reduce buffer usage in the iterator model and to improve communication costs for parallel execution. The scope of OLAP support afforded by these new functions far exceeds existing SQL functionality. Oracle and IBM have proposed these SQL extensions to ANSI to be included in the SQL-99 standard.


The Chicano Movement was flourishing throughout the southwestern part of the USA during the late 1960s. The movement was made up of a myriad of non-student and student activist groups in communities, colleges and universities. Its main goal was the economic, political and educational advancement of the Mexican community. Despite initial developments, by the late 1970s, some factions had declined primarily due to repression and violence from the state, patriarchal domination, and from internal ideological conflicts. This study examines the decline of a faction of the movement formerly known as the East Los Angeles Brown Berets between 1967 and 1973. The study focuses on the state and its intersections with 'mutually constructing systems' of oppression — racism, sexism, and class — that contributed to the demise of the Brown Berets.


Overreliance on mono-method approaches in research is an issue that compromises increases to measurement validity, confining the utility of our instruments (Bornstein, 2015a; Natoli, in press a). Multimethod approaches, however, often yield more comprehensive and precise data (Ganellen, 2007). Accordingly, multimethod research designs must be utilized when developing and refining measures of personality to make certain that these instruments are truly psychometrically sound. The Level of Personality Functioning Scale (LPFS; APA, 2013) was introduced in DSM-5 and offered to clinicians as a tool to assist in personality disorder diagnosis and to serve as a general tool for measuring personality functioning on a broad continuum. Since its introduction, myriad studies have evaluated the LPFS's psychometric properties. But at what frequency were mono-method research designs used in studies that purportedly contribute to, or document, this instrument's psychometric properties? This systematic review demonstrates the lack of multimethod research designs used to evaluate the LPFS's construct validity. Findings are discussed with regard to the need for multimethod research assessing the psychometric properties of the LPFS and other measures of personality; future directions for doing so are proposed and the unique opportunity offered by the LPFS to initiate a shift in the common practice of instrument validation is acknowledged.


8th October. Professor Droop reports on the nature of the work as follows:—Four more trenches were cut in the Vicarage Field. One was parallel to and close to Vicarage Lane. This being the part furthest from the ditches, it was thought that here was the only chance of hitting the wall of some building. The trench, however, found only virgin clay (' marl') under a thin gravel layer and in one place cobbles, which however from the associated pottery appeared to be modern rather than Roman. The other three trenches were cut more or less radially down the hill in the western part of the field with a view to confirming last year's results. The first trench, continuing that unfinished last year, found close to the Churchyard wall two ditches. The next further east found a third ditch paved and revetted with stone, between the first two. And the third trench containing one cut in 1928 which had already discovered the innermost ditch, revealed two ditches between it and the outermost ditch. This runs beneath what is the obvious rampart before excavation. There was evidence that after the beginning of the fourth century the outer line had been remodelled, the wall that revetted the rampart had been pulled down, the rampart carried forward with clay on to the berm, and a parapet wall built on the top. This series of ditches seems to have been intended to flank the roadway discovered in 1927 and 1928 further to the east. Five coins of the third and fourth centuries were found. There was little pottery; the coarse ware being mainly late, and the Samian mainly second century. The tip of a scabbard, a stud, and a small section of chain were the only small finds. A hole was also dug east of the church in the hope of picking up the continuation of a wall believed to be Roman, which was discovered when the chancel was remodelled in 1911, running east and west. This, however, was not found. The hole contained a mixed deposit of medieval and Roman pottery in which the latter predominated.


– Workers are a fundamental part in the development and growth of organizations since their operation and productivity depend on them. Therefore, one of the factors to consider is the job performance and staff turnover of a company for better growth. The objective of the research was to determine the relationship between staff turnover and job performance of janitors and cleaning workers in a SME (Small and Medium-Sized Enterprise). The methodology had a quantitative approach, with a non-experimental design, cross-sectional and correlational level. The sample consisted of 120 workers, including janitors and cleaning workers; to whom a survey was applied to collect information. The results obtained showed a value p<0.05; therefore, the null hypothesis is rejected; in addition, a moderate positive correlation (r = 0.359) was determined between staff turnover and job performance; likewise, a moderate positive correlation (r = 0.380) between voluntary turnover and job performance; finally, a moderate positive correlation (r = 0.352) between involuntary turnover and job performance. It was concluded that there is a relationship between staff turnover and job performance of janitors and cleaning workers in the SME company.


Acne vulgaris has been treated usually with antibiotics. Propionibacterium acnes (P. acnes) play a crucial role in its pathogenesis, however, P. acnes has been described to develop antibiotic resistance.


Great Union of 1918 strengthened and unified national market under the conditions in which the land offered an answer to the overall need to allot the peasant-soldiers. The land reform of 1921 in Romania was carried out within the democratic interwar context of some transformations which had as their result the national unitary state – geopolitically speaking –, the universal suffrage –socially speaking – the increase share of agriculture within the country's economy – economically speaking –. Land reform achieved by the importance of the legislation, both economically and socially the liquidation of large landowning, size decrease of large estates, the strengthening of the economic role of small peasant homestead, the intensification of capitalist economic development, the distribution change of landed property and distribution of forces change within the economic, social and political life of the country. Given the size of the expropriated area and number of allotted peasants, Romania ranked first in Europe.


The solution of partial differential equations has generally been one of the most-vital mathematical tools for describing physical phenomena in the different scientific disciplines. The previous studies performed with the classical derivative on this model cannot express the propagating behavior at heavy infinite tails. In order to address this problem, this study addressed the fractional regularized long-wave Burgers problem by using two different fractional operators, Beta and M-truncated, which are capable of predicting the behavior where the classical derivative is unable to show dynamical characteristics. This fractional equation is first transformed into an ordinary differential equation using the fractional traveling wave transformation. A new auxiliary equation approach was employed in order to discover new soliton solutions. As a result, bright, periodic, singular, mixed periodic, rational, combined dark–bright, and dark soliton solutions were found based on the constraint relation imposed on the auxiliary equation parameters. The graphical visualization of the obtained results is displayed by taking the suitable parametric values and predicting that the fractional order parameter is responsible for controlling the behavior of propagating solitary waves and also providing the comparison between fractional operators and the classical derivative. We are confident about the vital applications of this study in many scientific fields.


This article examines the relationship between 2 study away experiences—study abroad and service-learning—and the development of a global perspective. Three different studies are presented using cross-sectional and longitudinal designs and multi-institutional samples. The results specifically link involvement in study abroad and service-learning to the varying dimensions of the Global Perspective Inventory, demonstrating the influence such involvement has on student learning and development across cognitive, intrapersonal, and interpersonal domains. The article concludes with a discussion of the results and implications for administrators and practitioners interested in assessing global learning on their campuses.


Based on the comparative analysis of instructions for authors in 10 abroad medicine journals included in SCI and 11 Chinese medical journals,we found that the instructions for authors of journals abroad have complete information and elaborate description,while the instructions in Chinese journals are abridged and short.We should standardize the information of instructions for authors in our medical journals for improving the quality of manuscripts and the influence of our medical journals in the world.


To evaluate the impact of baseline left ventricular ejection fraction (LVEF) and its interaction with low‐gradient aortic stenosis (LGAS) on all‐cause mortality after transfemoral aortic valve implantation (TF‐TAVI).


Based on the bending theory of beams, combining with the constitutive relationship of shape memory alloy materials, the asymmetric bending of shape memory alloy beams under concentrated load was studied. Considering tension-compression asymmetry on both sides of the tension and compression in the process of bending, tension-compression asymmetry coefficient was introduced, by using the step-by-step method. The stress distribution, neutral axis displacement, curvature and phase boundary of the beam sections of the I-shaped cross-section shape memory alloy beam were analyzed. The results show that under the same load, the maximum offset of the neutral axis displacement increases with the increase of tension-compression asymmetry coefficient. Under the same tension-compression asymmetry coefficient, the displacement and curvature of the neutral axis increased with the increase of load; as tension-compression asymmetry coefficient increased, the proportion of mixed phase increased gradually, the proportion of martensite phase decreased, and the asymmetry of phase boundary became more obvious. Under the same conditions, the rectangular section is more suitable. The cross section of I shaped cross section was prone to occur phase transformation.


The present invention relates to a casting process of cast-steel gear. It includes cast-steel gear wheel hub and wheel rim, and it is characterized by removing technical padding of side surface of cast-steel gear wheel hub and wheel rim, and relatively reducing hot spot of wheel hub and wheel rim, making wheel rim hot spot modulus be 2.7 and making wheel hub hot spot modulus be 3.2.


Objective To explore the effects of vitrectomy combined with intraocular photocoagulation for vitreous hemorrhage.Methods 263 cases of vitreous hemorrhage from our hospital since 2008,who were carried out with vitrectomy and intraocular photocoagulation,were analysed.Results Visual function of 197 cases was improved,that of 66 patients unchanged.Followed up for 3~24 months,an average of 12 months,visual acuity in 197 eyes(75%) was significantly improved.Visual acuity after treatment was improved compared with that before treatment,the difference was significant(χ2=335.85;P=0.00).Iatrogenic retinal break was the main intraoperative complications after surgery.The major complications included anterior chamber inflammation,high intraocular pressure,vitreous bleeding and cataracts.Conclusion The treatment of vitrectomy combined with intraocular photocoagulation can improve visual acuity of patients and prevent the disease deteriorate effectively.


An organocatalytic azide-aldehyde [3+2] cycloaddition (organo-click) reaction of a variety of enolizable aldehydes is reported. The organo-click reaction is characterized by a high rate and regioselectivity, mild reaction conditions, easily available substrates with simple operation, and excellent yields with a broad spectrum of substrates. It constitutes an alternative to the previously known CuAAC, RuAAC, and IrAAC click reactions.


To the Editor: To improve the management of individuals with type 2 diabetes mellitus (DM) and chronic kidney disease (CKD), international guidelines recommend optimal control of various factors for the progression of kidney and cardiovascular disease. However, achievement of recommended objectives, a basic aspect of treatment and care, remains subject to many parameters, including healthcare costs and adherence to treatment. Socioeconomic level, age, and race considerably affect adherence to treatment. It has also been suggested that sex could influence adherence because women and men differ in their health beliefs and behaviors. The aim of this study was to determine the achievement of objectives recommended by the guidelines according to sex in a cohort of elderly adults with DM and CKD.


Two-dimensional Navier -Stokes and energy equations have been solved numerically for unsteady laminar flow in periodic wavy (sinusoidal and triangular) channels. The flow in the channels has been observed to be steady up to a critical Reynolds number. Beyond the critical Reynolds number the flow becomes selfsustained quasiperiodic oscillatory. This transition of flow occurs at lower Reynolds number for triangular channel relative to sinusoidal channel. The frequencies of oscillations, the friction factors and Nusselt numbers are reported.


Most of the high voltage insulation systems, such as the power cable joint having hetero interface, are composed of more than two different insulators to improve insulating performance. The partial discharge(PD) in these hetero interface is expected to affect the total insulation performance. Thus, it is important to study electrical properties on these interfaces. This study described the influence of copper and semiconductive substance defects on -q-n distribution between the interface of the model cable joints to classify PD source. PD was sequentially detected for 600 cycles of the applied voltage. The K-means cluster analysis has been analyzed to investigate the -q-n distribution. The skewness-kurtosis(Sk-Ku) plot from K-means clustering results was defined to quantify cluster distribution and classify distribution patterns. The Sk-Ku plot is composed of skewness and kurtosis along abscissa and ordinate which indicate the asymmetry and the sharpness of distribution. As a result of the Sk-Ku plot, it was confirmed that the data was distributed in 1st 2nd and 3rd quadrant at copper foreign substance defect, but in case of semiconductive foreign substance, the data was distributed in 2nd quadrant only.


A compact and inexpensive instrument (durometer) was tested for its ability to quickly estimate the specific gravity in the outerwood of 18-year-old Douglas-fir (Pseudotsugamenziesii (Mirb.) Franco...


The Centre of Achievement and Performance (CfAP) at the University of Northampton delivers a pre-enrolment module entitled "Study Skills for Academic Success". In early 2013 the course team embarked upon an intensive 2-day workshop to re-design the course for online delivery (and create OERs). We worked closely with the University's Professor of Learning and Teaching in Higher Education and a team of Learning Technologists to achieve this aim. The course will be piloted in April 2013 and rolled out from September 2013. This poster will disseminate our work more widely and hopefully encourage comment and suggestions from the learning development community which may help us develop our work.


Occupancy mapping has been widely utilized to represent the surroundings for autonomous robots to perform tasks such as navigation and manipulation. While occupancy mapping in 2-D environments has been well-studied, there have been few approaches suitable for 3-D dynamic occupancy mapping which is essential for aerial robots. This paper presents a novel 3-D dynamic occupancy mapping algorithm called DS-K3DOM. We first establish a Bayesian method to sequentially update occupancy maps for a stream of measurements based on the random finite set theory. Then, we approximate it with particles in the Dempster-Shafer domain to enable real-time computation. Moreover, the algorithm applies kernel-based inference with Dirichlet basic belief assignment to enable dense mapping from sparse measurements. The efficacy of the proposed algorithm is demonstrated through simulations and real experimentsiiThe code is available at: https://github.com/JuyeopHan/dsk3dom_public.


The synthesis of copper soap (laurate), and its complex with 2-amino 6-
methylbenzothiazole and their elemental and spectral analysis have been done for comparative studies
using IR, NMR, Mass and ESR spectra.

The fungicidal activities, with reference to Alternaria alternata and Aspergillus niger at
different concentrations by P.D.A. technique were also studied.

The present research work comprises detailed thermal analysis using
TGA technique to determine their kinetic and thermodynamic parameters by applying various
equations like Freeman Carroll, Coats-Redfern equation, Horowitz-Metzger equation, Broido
equation, Piloyan–Novikova equation.


Kaolinite (KGa-1b) and montmorillonite (STx-1b) reference samples were studied by infrared spectroscopy at various water contents. The spectral features reflecting the formation of water layers on the basal surfaces of individual minerals have been studied. Experimental studies were carried out by the Attenuated Total Reflection (ATR) Fourier Transform Infrared (FTIR) spectroscopy. The analysis of the composition of the wet samples was carried out by decomposing the experimental spectra into the spectrum of H2O and minerals in the air-dry condition. The obtained dependences of the participation coefficients of the basic spectra on humidity are compared with the results of measurements in the microwave range and make it possible to investigate the integral features of the formation of a water layer on mineral particles and to predict the plasticity of clays. The anomalous position of the maximum and the half-width of the stretching vibrational modes of water molecules at low water content have been established.