Many teens today feel as though they have limited opportunities to prove to society that they can make positive and meaningful contributions to their communities. They are presented with few opportunities to make important choices and decisions regarding their lives and communities and often have no mechanisms in their everyday lives to help them engage in meaningful ways in their communities (Youniss, Christmas-Best, Diversi, et al., 2002). In this article, we explore how Arts-UP, a summer art education program for urban teens, fosters self and social transformation by helping youth engage in their local community. Results demonstrate that Arts-UP participants see themselves as part of a larger community of artists, and also as active participants in their communities. We argue that programs like Arts-UP are imperative in creating not only future artists, but also future activists who will be critical thinkers and active, democratic citizens.


OREIGN exchange markets during 1980 were dominated by ac~iivityin domestic financial markets throughout the world. Dramatic changes in the direction of international capital flows during the year reflected the relatively volatile interest rate movements in the United States. While these interest rate movements appeared to be the major force affecting exchange rates during the period, however, rising rates of inflation and inflationary expectations, as well as midyear recessions in most industrial countries, also influenced exchange rate movements.


A series of 1, 3-diaryl-2-propene-1-ones have been synthesized by using Claisen-Schmidt condensation method in alkaline solution. The structures of the products were confirmed by spectral analysis (IR, 1H NMR and Mass). All the newly synthesized compounds were screened for their antibacterial and antifungal activity.


Factorial moments are convenient tools in nuclear physics to characterize the multiplicity distributions when phase-space resolution ($\Delta$) becomes small. For uncorrelated particle production within $\Delta$, Gaussian statistics holds and factorial moments $F_q$ are equal to unity for all orders $q$. Correlations between particles lead to a broadening of the multiplicity distribution and to dynamical fluctuations. In this case, the factorial moments increase above 1 with decreasing $\Delta$. This corresponds to what can be called intermittency. In this letter, we show that a similar analysis can be developed on financial price series, with an adequate definition of factorial moments. An intermittent behavior can be extracted using moments of order 2 ($F_2$), illustrating a sensitivity to non-Gaussian fluctuations within time resolution below 4 hours. This confirms that correlations between price returns start to play a role when the time resolution is below this threshold.


Facial myokymia are subtle involuntary undulating or vermicular muscular contractions that spread throughout the striated muscles supplied by the facial nerve [1]. Simultaneous or sequential triggers activate one or multiple motor units, and usually manifest as spontaneous muscular activity with brief repetitive discharges of action potentials that repeat rhythmically or semi-rhythmically. Short intervals of irregular electrical silence between 100 and 200 milliseconds (and up to 3 seconds) occur before the next myokymia discharge [2].


Gupta and Kumar (2000) introduced a random model to study throughput scaling in a wireless network with static nodes, and showed that the throughput per source-destination pair is Θ (1/√n log n). G...


Sporadic inclusion body myositis (sIBM) is the most common acquired myopathy in patients older than 50 years of age. sIBM is hardly responds to any immunosuppressing theraphies, and its pathophysiology remains elusive. This study aims to explore pathogenic pathways underlying sIBM and identify novel therapeutic targets using metabolomic and transcriptomic analyses.


The study of the complement system was for a long time, not without some justification, looked upon as one of the more esoteric immunological pastimes and it is only in recent years that investigations of complement function have found a substantial place in clinical practice. From such studies has come the recognition, on the one hand, that complement component levels can be useful in the diagnosis and management of many 'immunological' diseases; and on the other hand, that there are to be found individuals with genetic deficiencies of various complement components, the study of whom can help to clarify the in vivo role of the complement system. In the field of dermatology perhaps the best example of this interaction concerns hereditary angiooedema (HAE). Although this disease has been recognized since the middle of the nineteenth century (Quincke, 1882; Osier, 1888) it was not until 1963 that Donaldson & Evans demonstrated that it was associated with a deficiency of the Ci-inhibitor. This serum protein, also described as a2 neuraminoglycoprotein, inhibits a number of serine histidine esterases found in blood plasma. These include, besides Ci itself, plasmin, kallikrein, activated Hageman factor (Xlla) and activated plasma thromboplastin antecedent (XIa). HAE is a dominantly transmitted disease and affected subjects are heterozygotes having low levels of inhibitor rather than none. The characteristic episodes of angio-oedema appear to be precipitated by local exhaustion of the reduced amount of inhibitor allowing apparently autocatalytic activation of Ci. This in turn leads to the wholesale activation of C4 and C2 with the generation of a kinin-like substance which appears to be the principal mediator of the disease. It is not clearly known what initiates the attack. The only certain predisposing factor is trauma. However, it seems likely that the activation of any of the enzyme systems that can consume the inhibitor can give rise to local exhaustion and spark off an attack. What brings an attack to a close 48-72 h later is also not understood but it is known that administration of inhibitor systemically can rapidly bring attacks to an end (Pickering et al., 1969). The inhibitor is usually administered in the form of fresh frozen plasma but since this contains further substrates for activated Ci it would be preferable to give purified inhibitor and a source of this is likely to become available in the near future. Furthermore, prophylactic treatment of HAE is possible using epsilon amino caproic acid, or its analogue tranexamic acid, which inhibits the activation of the whole spectrum of plasma enzymes with which the Ci inhibitor reacts. An increasing number of trials with this treatment have been made since it was first introduced by Lundh et al. (1968) and there seems little doubt that for most patients it is effective. This is therefore a disease where both prophylactic and therapeutic treatment have been developed as a direct result of an increased imderstanding of pathogenesis. Since there is now treatment available the diagnosis of HAE is no longer only of academic interest. In most cases, dermatologists make the diagnosis clinically without laboratory help but levels of Ci inhibitor can readily be measured by esterolytic techniques and this allows the diagnosis to be confirmed. Other primary deficiencies of complement may also be associated with diseases with skin manifestations. Moncada et al. (1972) have described a family with a deficiency of Cir where the affected members suffer from repeated infection or from a disease resembling systemic lupus erythematosus accompanied by somewhat unusual skin lesions but without the characteristic serological abnormalities of SLE.


A great amount of research has focused on nutritional genomics in order to personalize dietary interventions based upon genetic premises. The aim of nutritional genomics research is to use this information as a preventive tool in primary care, through personalized dietary advice to populations or to individuals. Increasing the understanding of genetic traits on the part of dieticians and other healthcare professionals can complement the data that is required to create personalized recommendations for dietary intervention. A to establish a healthcare system that supports and rewards these approaches and promotes their application.


West Nile Fever is a zoonotic disease caused by the West Nile virus, which belongs to the family . The transmission happens due to the bite of mosquitoes Culex spp . and it was first recorded in West Africa, but time by time the virus spread to others continents. Equines have quite a predisposition for this pathology and birds are the main reservoir. Once within the organism, the pathogen starts to replicate until it gets to the central nervous system, which is when it triggers encephalitis, and the neurological symptoms begin. Histologically, it can present inflammation of the neuronal tissue, variable degrees of necrosis and gliosis, and in the necropsy no lesions could be found. The diagnose is made with the physical examination, serological analysis and PCR test. The treatment is supportive for infected patients.


ABSTRACT By hydrothermal liquefaction (HTL) of organic matter, hydrochars are produced which may be applied to soil for carbon sequestration. From substrates of wild seaweed and organic waste digestate, we measured the distribution of solids (hydrochars) and liquids after HTL at 150 and 200°C, 50 bar for 1 h. The output of liquids and solids was recorded. Elemental analysis was conducted for essential plant nutrients, potentially toxic elements (PTEs) and silicon in the hydrochars. Sequential extraction of phosphorous (P) was conducted to assess the P availability for plants. About 20% of the initial dry matter dissolved during HTL of digestate, and 55% for seaweed. More dry matter was dissolved by increased temperature. Except from arsenic in seaweed chars, the concentrations of PTEs were below quality compost thresholds. About 85% of P was recovered in chars for digestate. For seaweed, the recovery was 97% at 150°C, decreasing to 84% at 200°C. The solubility of P in chars decreased by HTL, and more with higher temperature. Reduced P availability, especially by higher temperature, is negative for the immediate fertilization effect. However, for soil sequestration of carbon, reduced P availability in hydrochars may expand the area where application may occur without negative environmental effects of eutrophication of water bodies.


Nave Bayesian Classifier is a simple and powerful method for text classification.Our improved method uses synonyms to filtrate the features of text,loosing the independent condition required by Bayesian method.We apply two different feature extraction methods in the iteration process,enhancing the representative ability of feature collection effectively.The experimental results show that our advanced method has obviously improved the performance of Nave Bayesian Classifier.


The Guanshan Biota from the Cambrian Stage 4 Wulongqing Formation is a typical Burgess‐shale type Lagerstätte that had witnessed the Cambrian explosion. Here we report two new localities of the Guanshan Biota, which is located at Baimei village, south of Kunming and Xinglong village, Wuding County, Yunnan Province respectively. Both localities produce soft‐body fossils and several new taxa, e.g. a new species of palaeoscolecidans (Palaeoscolex xinglongensis sp. nov.) reported herein. The comparative study of the new species with similar form not only indicates that there is a diversification of palaeoscolecid species in Guanshan Biota, but also strengthens the ties between the older Chengjiang Biota and the younger Kaili Biota (and also the coeval Burgess Shale community). Three paleoecological features, including high diversity, little disparity and richness of palaeoscolecid worms, are summarized as a case study to represent the differences between Guanshan and Chengjiang Biota.


Here presents a kind of electronic soft starting controller based on Intel196MC. The control function of the soft starter can be more accuracy through use of this MCU. The paper gives the main working principle and the main circuit of the soft starter, analyzed the production of the triggering signal and the design of the software. Then experimental results obtained from a prototype confirm the validity and feasibility of the proposed method.


The aim of this work is to analyze the role of Social Movements and Non - Governmental Organizations (NGOs) in the face of the agribusiness advance that remains fixed in the western state of Para, in the Lower Amazon region, in the context of agrarian geography. This theme has been much debated and faced by Social Movements and NGOs in western of Para. The methodology used occurred by mean of the theoretical conceptual revision and the fieldwork, using the technique of semi-structured interviews with members representing Social Movements and NGOs, as well as image records were made of the investigated area. It is noted that from the territorialization of capitalist and hegemonic agriculture, there were changes of the landscapes in the region and metamorphosed the socio-spatial and socio-territorial relations. In this perspective the implementation of logistic systems (ports, waterways and highways) in the western part of the Amazon region of the Para state, corroborates the aggravation and materialization of land grabbing, agrarian and territorial conflicts, maintenance of private property and land concentration.


The data-driven framework is one of the most demanded managements of cloud computing (CC). This study was focused on optimization and deep learning (DL) for the CC framework. It requires different types of frameworks' data or resources for executing various services on the cloud framework. We propose a model-based data-driven framework that explores data-driven management in terms of CC. This research is an optimal selection of CC recovery when the uncertainty of cloud networks can be based on time constraints and objective functions. We consider the emergence of CC data centers such as Amazon Web Services (AWS) and Wikipedia. These data centers can bring a considerable risk to the uncertainty of the data quality in real-time demand from organizational CC. In the present pandemic situation, data centers perform various degradation of the quality of data because the allocation of resources has increased the input of data size, especially in cloud workload. So, we use an Artificial Neural Network (ANN) model to perform a time allocation and elasticity for managing the CC workload and their management. Real-time workload resilience, trace troubleshooting, probability, and availability are implemented to analyze the data quality for better performance, which leads to overhead on the cloud platform performance.


Background Oxidative damage is a major cause of age-related cataracts,and the ubiquitinproteasome system is involved in lens differentiation and development.Ubiquitin carboxy-terminal hydrolase L1 (UCHL1),one of key enzymes of ubiquitin-proteasome system,was discovered to participate in the age related diseases and oxidative stress damage. Objective This study was to investigate the effects of UCHL1 on the formation and development of age-related cataract. Methods Lens capsule were collected from 24 patients with age-related cataract(including 12 cases of cortical cataract and 12 cases of nuclear cataract) during the surgery.Five normal lens capsule membranes were obtained from eye bank of Tongji University.Human lens epithelial cells (LECs) line (SRA01/04) was also collected in this study.Expression of UCHL1 in the lens epithelial layer of different samples was assayed using immunofluorescence technology.UCHL1 eukaryotic expressing vector was constructed and transfected into cultured SRA01/04 by liposome,and green fluorescent protein (GFP) eukaryotic expressing vector was transfected at the same method as the control group.UCHL1 over-expressing cells were then exposed to different concentrations (0.2,0.3,0.4 and 0.5 mol/L) of tert-butyl hydroperoxide (TBHP) for 24 hours and subsequently monitored for cell viability evaluation by MTT assay. Results Immunofluorescence showed that UCHL1 was expressed in human lens epithelial layer,but significantly different expressing levels were seen among normal lens capsular membrane,cortical cataract and nuclear cataract ( F =13.411,P =0.000),and UCHL1 expressing levels were lower in cortical cataract and nuclear cataract than the normal lens (P =0.000,P =0.000).No significant difference was found in UCHL1 expressing level between cortical cataract and nuclear cataract ( P =0.164).Western blot analysis verified that UCHL1 exhibited a stranger expression in the UCHL1 transfected group compared with the GFP transfected group,illuminating a successful transfection of UCHL1 in SRA01/04 cells.MMT assay revealed that the A570/630 value in UCHL1 transfected cells was significantly elevated in comparison with GFP transfected cells following the treatment of 0.3 mol/L TBHP. Conclusions UCHL1 has an antioxidative ability,and it might plays an important role in the progress of age-related cataract.

Key words:
Ubiqutin carboxyl-terminal hydrolase L1;  Ubiqutin;  Cataract;  Oxidative stress;  Eukaryotic expressing vector


Practice and Procedure: Procedure before the European Court of Human Rights Admissibility Checklist Convention Principles and Approach Sources of case law and information. Problem Areas: Fair Trial Guarantees Others. Just Satisfaction: General Principles Pecuniary Loss Non-pecuniary Loss Legal costs and Expenses Default Interest. Appendices.


The African continent in general, and South Africa in particular, have not been immune to the challenges faced by the global economy. These include a gradual but sustained slowdown, since the start of the decade, in real global demand for South African exports, in particular from China, as well as a major downward adjustment in the prices of our major commodity exports. These developments have eroded real export growth, incomes, and to some extent also corporate profitability in some sectors of the economy.


: In this work we propose a facile method of preparing cost-e ff ective clay-metaloxide / metal (CuO / Ag and ZnO / Ag) composite pellets for an e ffi cient water purification technique. Clay, with intrinsic antibacterial activity, served as a membrane support for di ff erent metaloxide / Ag nanoparticles (NPs) concentrations (2.5, 5 and 10 wt.%), as the active fillers. The e ff ect of time (24 and 48 h) on the bactericidal activity of these pellets was also monitored. The clay–nanocomposite pellets were characterized using: X-ray di ff raction, X-ray fluorescence, scanning electron microscopy, transmission electron microscopy, ultraviolet–visible (UV–Vis) spectrophotometry and nitrogen desorption analysis. The antibacterial activity performance was tested using E. coli and S. aureus strains of ATCC25922 and ATCC25923, respectively, in two aqueous media (nutrient broth and nutrient-free) by the colony-forming unit method. The results showed that the clay-CuO / Ag composite with a bandgap (1.24 eV) exhibited overall best performance under all conditions and time factors of ~100% e ffi ciency in nutrient-free medium for all concentrations and times and 20–40% e ffi ciency in nutrient broth for 24 h. The clay-ZnO / Ag with a bandgap of 2.88 eV showed no bactericidal activity in both media, except for that with 10 wt.% ZnO / Ag which showed 100% e ffi ciency in nutrient-free medium after 24 h. All the synthesized composites showed 100% bactericidal e ffi ciency in nutrient free medium after 48 h. These results indicate that, the clay / metaloxide / Ag could serve as e ffi cient water purification technique, with a potential for large-scale commercialization. These were then characterized and separately tested on clinical strain gram negative and gram positive bacterial species of E. coli (ATCC 25922) and S. aureus (ATCC 25923) respectively in a nutrient rich broth aqueous medium for 24 h and nutrient-free sterile aqueous medium for 24 and also 48 h using the colony forming unit (CFU) method for their antibacterial performance. The study aims to produce a cost-e ff ective and e ffi cient clay–nanocomposite for water purification at the point of water use. The isotherms provide qualitative information on the porosity of clay / CuO / Ag samples. According to the Type IV isotherms obtained, which are characteristic of pore sizes between 1.5 and 100 nm, these are classical signs of mesopores. The micropores were filled at very low relative pressure followed by the formation of a monolayer at the knee of the curve also at low relative pressure. At a moderate pressure, a multilayer of nitrogen gas molecules is formed and then as the pressure approaches a peak value there is condensation of nitrogen gas molecules in the pores (capillary condensation). The isotherm depicts H3 hysteresis type which is an indication that the pores have a slit shape. Gas adsorption is continuous at high P / P 0 which confirms the agglomeration of particles observed in the SEM analysis. micropores were filled at very low relative pressure followed by the formation of a monolayer at the knee of the curve also at low relative pressure. At a moderate pressure, a multilayer of nitrogen gas molecules is formed and then as the pressure approaches a peak value there is condensation of nitrogen gas molecules in the pores (capillary condensation). The isotherm depicts H3 hysteresis type which is an indication that the pores have a slit shape. Gas adsorption is continuous at high P/P 0 which confirms the agglomeration of particles observed in the SEM analysis.


In an attempt to make dried noodles with composite flours utilizing rice and wheat flours, noodle-making characteristics were improved by the addition of popped rice and wheat flours to rice flour. Their quality was studied in terms of physical properties, noodle-making characteristics, cooking quality test and sensory evaluation. Dried noodle of the composite flour was produced by the conventional method. The results are summerized as follows; 1. In comparing the composite flours, the rice flour containing 30% popped rice flour had a lower maximum viscosity than that with 40% popped rice flour by method of amylograph. The composite flour(20% rice+30% popped rice+50% wheat flour) with added 2% xanthan gum showed the viscosity characteristics which was similar to that of wheat flour. 2. Addition of xanthan gum and wheat flour to rice and popped rice flour mixture helped to improve the noodle making properties and the cooking quality, and the noodle making properties and the cooking quality of the mixed flour were almost the same as those of wheat flour alone. 3. The composite flour (rice+popped rice+wheat flour) with xanthan gum showed a higher score in sensory evaluation than that without xanthan gum. The general acceptability scores obtained with the noodle products made of the composite flours with 30% popped rice flour was not significantly different from that of noodle products made of wheat flour alone. However, the noodle products made of the composite flours showed rather higher scores in odor and palatability than the products made of wheat flour alone.


The application of radial probe endobronchial ultrasound (R‐EBUS) and virtual bronchoscopic navigation has improved the diagnostic outcome of bronchoscopy for peripheral pulmonary lesions (PPLs). Nonetheless, while existing navigation systems are very useful for selecting the bronchus containing the target lesion, the associated introductory costs are high. Therefore, we focused on virtual bronchoscopy (VB) using the workstation, ziostation that was already available in many countries as an adjunct modality.


Abstract To achieve long-term impact in the arena of gender equality, museums need to go beyond thematic educational activities and exhibitions. Museums need to become permanent spaces dedicated to problems of gender equality, advocate for changes that promote gender equality internally and externally and become acknowledged on local and national level as trusted organisations that bring together stakeholders and advocate for a more gender inclusive society. They need to serve as permanent places where questions around gender and science, technology, engineering and mathematics (STEM) are addressed on different levels. To this end, 14 science centres and museums in Europe and Israel worked together for three years as part of a common, European-funded project (Hypatia) in order to become Hubs for gender equality in their communities. Together, they created synergies, working with schools, industry and research centres as agents of change. At the end of the project, they listed a series of recommendations for the long-term implementation of Gender inclusion in STEM communication. They based these recommendations on the findings of the Horizon 2020 funded project 'Hypatia' in which they collaborated from 2015 until 2018, on their own experiences, and shared learning. Participating museums selected four places and sectors in which they planned to implement changes, thereby ensuring their actions would be sustainable: their own museum/science centre/network of science centres; research and industry institutions; schools; and within other informal science education organisations. Using tools developed by the project, including a Theoretical Framework for gender inclusion, a Toolkit of ready-to-use, hands-on activities for teenagers that address gender, national 'Hub' models, and input from young people, the Hypatia Project offers now insight and information on how the museum community can address gender inclusion in local and national communities. The lessons learned demonstrate how museums can act as tools to promote equitable STEM educational programming, preparing the next gender inclusive STEM-ready workforce.


The mass of the W boson is one of the most important parameters in the Standard Model. A precise measurement of the W boson mass, together with a precise measurement of the top quark mass, can constrain the mass of the undiscovered Higgs boson within the Standard Model framework or give a hint for physics beyond the Standard Model. This dissertation describes a measurement of the W boson mass through its decay into a muon and a neutrino using ~ 2.2 fb-1 of √ s = 1.96 TeV p$$\bar{p}$$ data taken with the CDF II detector at Fermilab. We measure the W boson mass to be (80.374 ± 0.015stat. ± 0.016syst.) GeV/c2. This result, when combined with the W mass measurement in the electron channel, leads to the single most precise mW value and greatly constrains the possible mass range of the undiscovered Higgs boson. iv


One of the solutions to reduce the sway oscillation motion of crane' cables is to use a passive damper. The application of this method is simple but limited in the insufficient flexibility to prevent adverse movements and to amplify the favorable ones. This paper proposes an on-off damping controller of semi-active damper to improve the passive damper. The aim of the on-off damping control is to amplify the radial motion of damper to increase the energy dissipated, then reduce the sway motion. The effectiveness of proposed controller are verified by numerical simulations of a 2D crane.


CV. Kasih dan Sayang is a Makalate chocolate manufacturer based in Makassar. The company has never measured the extent to which its marketing activities have an impact on sales and are considered effective in attracting consumers. The purpose of this research was to know and analyze the effectiveness of marketing of makalate chocolate product through SMS broadcast with Customer Response Index (CRI) and Return On Marketing Investment (ROMI) approaches. The methods used in this research were CRI and ROMI. Both methods are to measure the effectiveness of an advertising/marketing program in terms of audience response and use of marketing investment. The results showed that based on CRI calculations, the advertisement of makalate chocolate through SMS broadcast was effective until the intention stage (intention to buy), but it was not effective for the stage of buying makalate chocolate products. ROMI calculation also showed that the advertisement of makalate chocolate through SMS broadcast was not effective in terms of marketing investment because the value of Hurdle Rate was greater than ROMI calculation.


We study an antiferromagnetic order in the ground state of the half-filled Hubbard model on the Penrose lattice and investigate the effects of quasiperiodic lattice structure. In the limit of infinitesimal Coulomb repulsion $U \rightarrow +0$, the staggered magnetizations persist to be finite, and their values are determined by confined states, which are strictly localized with thermodynamics degeneracy. The magnetizations exhibit an exotic spatial pattern, and have the same sign in each of cluster regions, the size of which ranges from 31 sites to infinity. With increasing $U$, they continuously evolve to those of the corresponding spin model in the $U=\infty$ limit. In both limits of $U$, local magnetizations exhibit a fairly intricate spatial pattern that reflects the quasiperiodic structure, but the pattern differs between the two limits. We have analyzed this pattern change by a mode analysis by the singular value decomposition method for the fractal-like magnetization pattern projected into the perpendicular space.


Mesoproterozoic mafic dyke swarms are extensively developed in the Western Shandong,the east of the North China Craton,which intruded the Early Precambrian crystal basement.The dorminant orientation of these mafic dykes is nearly N-S trending.The mafic dyke swarms in the Western Shandong belong to LREE enrichment magmatic rocks,and are formed in a continental rift environment according to petrology and geochemistry of these mafic dykes.The flow structures and geometry evidences of the dykes indicate that the magma source of these dykes intruded the pre-existing tensional rupture.The dyke swarms in the Western Shandong intruded from North to South.Angles between the long axis orientations of magnetic fabric textures and the middle line of dykes suggest that the flow direction of these dykes is from North to South.Further it indicate that the dykes intruded from North to South.These flow structures,geochemistry and magnetic fabric textures suggest that magma come from enriched mantle magma source beneath the Yanliao-Zhongtiao aulacogens based on space-time relationship between the mafic dyke swarms and Yanliao-Zhongtiao aulacogens.


The experimental results of the search for the Standard Model Higgs boson with the ATLAS detector at the Large Hadron Collider are reported, based on a dataset of pp collision data with an integrated luminosity of up to 4.9 fb^-1 at sqrt{s}=7 TeV. The search combines several Higgs boson decay channels in a wide range of Higgs boson masses from 110 GeV to 600 GeV. A Standard Model Higgs boson is excluded at the 95% confidence level in the mass ranges from 110.0 GeV to 117.5 GeV, 118.5 GeV to 122.5 GeV, and 129 GeV to 539 GeV, while the range from 120 GeV to 555 GeV is expected to be excluded in the absence of a signal. The most significant excess of events is observed around 126 GeV with a local significance of 2.5sigma. The global probability for such an excess to occur in the full searched mass range is approximately 30%.


Scientific classifications must be based on good research and generate useful hypotheses. The one offered here may not measure up to this ideal, but it is based on accumulated and precious knowledge, and it should be recognized as a good foundation for psychiatry. I felt encouraged by the fact that, when systematized, such early classifications showed a clear pattern. In an earlier chapter, I have dealt with major diseases as if they were independent entities. Now, I should like to analyse their components in detail.


Abstract Climacium is a small but morphologically distinctive genus ("tree mosses") with four species distributed primarily in the Northern Hemisphere. Climacium dendroides occurs around the globe at northern latitudes with disjunct populations in Mexico and New Zealand, whereas C. americanum and C. kindbergii are endemic to eastern North America and C. japonicum is limited to eastern Asia. Using nucleotide sequence data from five plastid loci plus the nuclear ribosomal ITS region we assessed evidence for monophyly of taxonomic species and tested the hypothesis that C. americanum and C. kindbergii from eastern North America have a sister group relationship with C. japonicum from eastern Asia. Climacium japonicum is resolved as sister to a clade containing the circumboreal C. dendroides, C. americanum, and C. kindbergii. Climacium americanum and C. kindbergii were not resolved as monophyletic based on sequence data but together they composed the sister lineage to C. dendroides. Geographically disjunct populations of C. dendroides in Asia, Mexico, the United States, and Canada vary at only a few polymorphic nucleotide sites across the three loci. The disjunctive New Zealand plants of C. dendroides are related to Asian accessions.


Objectives This research intends to explore the virulence of Beauveria bassiana to Culex pipiens pallens and to provide a theoretical basis for dealing with mosquito resistance to chemical insecticides and allowing greater biological control of mosquitoes.Methods A spore suspension of B.bassiana was used to treat eggs and larvae of Cx.pipiens pallens in different instars.The survival rate of larvae and the hatching rate of eggs were recorded and the impact of larval density on the strain's virulence was determined.Results The earlier the instar of the Cx.pipiens pallens larvae,the greater the sensitivity to the strain.After the 10 d of treatment with B.bassiana,the mortality of 1st instar and 2nd instar larvae reached 100%.The strain's weakest virulence was among 4th instar larvae.With an increased concentration of the spore suspension,the strain's inhibition of the hatching of eggs of Cx.pipiens pallens improved.When the concentration of the spore suspension reached 1×107 spores/ml,only 25% of the eggs hatched.The virulence of the strain is influenced by larvae density.The higher the density of larvae,the better the pathogenic effect is.Conclusion Under laboratory conditions,B.bassiana provided efficient control of Cx.pipiens pallens and could be used in the biological control of mosquitoes.


Dorsal anterior cingulate cortex (dACC) is related to cognitive function and seems to have an important role in decision-making. After training, rhesus macaques can serve as a good model to study choice behaviour. During decision, a lot of factors are considered but will focus on the values of presented offers and their probabilities. The aim of this project is to find a model that would accurately describe variables which guide the animal behaviour during a gambling task and to test if these variables are encoded in dACC. To achieve these objectives, an analysis of behavioral data was performed, making a comparison between models of expected and subjective offers' value. The model of expected value was done considering each offer as the sum of the two values (gain and loss) multiply by the correspondent probability. Then, extending this concept, the model of subjective value was defined according to the prospect theory. Also, an analysis of the electrophysiological data was done, looking for neural correlates of model variables. The results have shown that the animals learnt the task and made their decisions considering the relevant task parameters. In addition, we found that the model based on prospect theory better explains animal behavior than the expected value model. Moreover, an overweight of the parameters related to gains and an underweight of the ones related to losses was observed. Analysis of the firing rates of dACC neurons revealed encoding of offer values in correspondence with the behavioral models. In addition, there was a clear distinction in neuronal activity between gains and losses. These results confirm the relation with dACC and decision making, and the fact that the different parameters are weighted before being analyzed when a decision has to be made. In this case, wins were more relevant than losses. The natural extension of this work for the future would be to model transformation of probabilities apart from offer values in order to understand better the decision process. Also, making similar studies in other brain areas could help to answer which areas contribute in the process and how the information is linked among them. These types of studies can help us to understand the decision mechanisms in a better way.


Participation of opioidergic mechanisms in implementation of inhibitory effects of the brain "punishment areas" upon nociceptive afferentation, was studied. The antinociceptive effect of electrical stimulation of the "areas" was either enhanced or reduced by naloxone depending on the current strength. The role of the opioids was shown to diminish with age. The results suggest that the opioids are more significant in the realization of the antinociceptive influences woned by stimulation of the "brain rewarding" than the "brain punishment areas".


The invention relates to a wind farm reactive comprehensive optimization control method. The method comprises the following steps of: inputting signals into a wind farm reactive comprehensive optimization control system; switching plant or wind farm grid combining point capacitors and reactors, controlling a static var compensator (SVC) and controlling wind farm units by using the wind farm reactive comprehensive optimization control system. Through the scheme, the automatic control level of wind farm scheduling, the utilization ratio of reactive configuration equipment and the voltage stabilization level of a power grid can be improved, and reactive power comprehensive optimization coordination control over wind farms is realized.


A critical assembly known as the detailed cell was constructed as part of the Light Water Breeder Reactor (LWBR) Development Program to provide basic experimental data and to confirm nuclear analysis methods. A unique feature of the critical mock-up is the capability to move the entire seed assembly remotely. Experiments were conducted with different seed and blanket configurations, and extensive three-dimensional power distribution measurements were performed. 20 references. (NSA 29: 34265)


Backgroud: Serum gamma-glutamyl transferase (GGT) enzyme activity found predominantly in diseases of the liver, biliary tract and pancreas. GGT level could act as predictor to liver fibrosis. Aims: To investigate the relationship between GGT levels and histopathological hepatic assessment in patients with chronic hepatitis C. Material and Methods: This study included 130 patients suffering from chronic hepatitis C (CHC) infection who referred to Hepatology and Gastroenterology outpatient clinic at Shebin El-Kom Teaching Hospital to be enrolled in the National Committee for Control of Viral Hepatitis (NCCVH) from March to November 2014 before starting antiviral therapy by with peg-interferon/ribavirin (peg-IFN/RBV). All patients were evaluated histopathologically by liver biopsy and GGT level was meased. Results: GGT is elevated in CHC patients (Mean ± SD 68.8±39.6) the upper limit of GGT (up to 30 U/L). While, there was no correlation between GGT levels and quantative PCR assay of HCV RNA. There was a positive correlation between body mass index (BMI) and degree of hepatic steatosis in the studied cases (p-value <0.001). Histopathological assessment of liver biopsy by Ishak and Metaver scoring systems revealed highly significant statistical difference between different stages of fibrosis and degrees of hepatic steatosis regarding GGT level (p-value <0.001) with positive correlation between GGT levels and staging of fibrosis, hepatitis activity index (HAI) and degree of steatosis (p-value <0.001). According to the area under the curve (0.944), GGT was a significant indicator to advanced fibrosis at a cutoff point 63.5U/L with sensitivity 91.9% & specificity 79.6% in indicating advanced liver fibrosis. Conclusion: GGT levels can be taken into consideration to predict stage of liver fibrosis and degree of hepatic steatosis.


ABSTRACT Series and parallel systems consisting of two dependent components are studied under bivariate shock models. The random variables N1 and N2 that represent respectively the number of shocks until failure of component 1 and component 2 are assumed to be dependent and phase-type. The times between successive shocks are assumed to follow a continuous phase-type distribution, and survival functions and mean time to failure values of series and parallel systems are obtained in matrix forms. An upper bound for the joint survival function of the components is also provided under the particular case when the times between shocks follow exponential distribution.


Application of direct radiation pattern estimation in finite difference time domain (FDTD) simulation environment as an alternative to cumbersome near-to-far field transformation is considered. With the proposed improvement, direct estimation of the radiation pattern from the field strength samples in FDTD method becomes significantly less sensitive to the antenna geometry and thus more applicable to practically relevant cases. The main idea is to use field samples taken at two different radii to account for antenna geometry. The samples are taken at radii that are as close as possible to the antenna but still not too close to spoil the correctness of the results. The introduced improvement, combined with multigrid simulation domain and higher order accuracy FDTD formulations, reduces the necessary size of the computational domain, which directly leads to reduced memory consumption and a smaller error due to numerical dispersion.


Deep transfer learning (DTL) techniques attempt to tackle the limitations of deep learning, the dependency on extensive training data and the training costs by reusing obtained knowledge from source data for target data. However, the current DTL techniques suffer from either catastrophic forgetting dilemma (losing the previously obtained knowledge) or overly biased pre-trained models (harder to adapt to target data) in fine-tuning pre-trained models or freezing a part of the pre-trained model, respectively. We propose a new continual/progressive learning approach for deep transfer learning to tackle these limitations. We extend the pre-trained model by expanding pre-trained layers (adding new nodes to each layer) in the model instead of only adding new layers. Hence the method is named EXPANSE. Our experimental results confirm that we can tackle distant source and target data using this technique. At the same time, the final model is still valid on the source data, achieving a promising deep continual learning approach. Moreover, we offer a new way of training deep learning models inspired by the human education system. We termed this two-step training: learning basics first, then adding complexities and uncertainties. The evaluation implies that the two-step training extracts more meaningful features and a finer basin on the error surface since it can achieve better accuracy compared to regular training.


PURPOSE: A solid state imaging device having a photodiode and a mosfet and method of manufacturing the same is provided to be capable of improving the performance of elements. CONSTITUTION: A readout gate electrode(13a) is selectively formed on a silicon substrate. An N-type drain region(14a) is formed at one end of the readout gate electrode(13a), and an N-type signal storage region(15) is formed at the other end thereof. A P(+)-type surface shield region(21a) is selectively epitaxial-grown on the signal storage region(15), and a silicide block layer(19) is formed on the surface shield region(21a) to cover at least part of the signal storage region(15). A Ti silicide film(33a) is selective epitaxial-grown on the drain region(14a).


Excessive salinity is the major problem facing the future development of our nation. It is a concern of professional engineers, economists, educationalists, accountants, as well as agriculturalists and politicians. Saline degradation affects our rural and regional areas and the infrastructure of towns and cities. There are many solutions to these problems, which need to be co-ordinated. A multidisciplinary approach is needed to implement those solutions, so that our nation may thrive. A programme of mobile antisalinity conferences is being organised to find, analyse and implement solutions to our salinity problems. It reviews remediation techniques overseas, as well as in Australia. This paper reviews the exposure of a wide spectrum of people to the scourge of rising water tables and resulting salinity and makes recommendations to find solutions. This programme of sustainability and thrivability is inaugurated in the wheatbelt of Western Australia and is being operated in other regions of our continent, including the Brigalow, the Coorong, the Murray-Darling, the Eyre, the Wimmera and the Mallee. The antisalinity solutions cover a wider range of technologies and are being disseminated internationally, for the benefit of our world.


Abstract A formula is derived for the heat of solution of a binary alloy in terms of the pseudopotentials of the components. Though existing pseudopotentials are inherently not accurate enough to permit the calculation of such heats for the alkalis directly, an indirect argument plausibly explains the widely varying solubilities in binary alkali systems.


In Japan, the area of marine forest has decreased by 40% in the last 30 years, due to environmental changes. To develop Low-carbon society, it is inevitable to restore and expand marine forests and promote the carbon sequestration by seaweed in the coastal zone. Especially, Hokkaido, which locates in the subarctic zone, has 200 000-ha marine forest which shares 20% of the domestic total. The restoration of marine forest in the coast al zone would also promote the development of industries in the area. In this project which is commissioned by Ministry of Economy, Trade and Industry, we made a unit which consists of companies, local residents, self-governing bodies and government. We conducted the experimental study to develop CO2-absorption system at marine forest which locates along the shore in subarctic zone area by using agriculture-and-manufacturing recyclable resources. The objects of this project are as follows. The first is to reduce CO2 emission by using iron and steel slag instead of concrete as the material of building blocks and stones, which compose part of marine forest. The second is to enhance CO2 absorption by supplying iron from the installed unit attached to the building blocks and stones which comprise marine forest, and promoting growth of seaweeds such as kombu. The last is to sequestrate carbon by manufacturing oil and resin, which could be used for industrial products, from the elements


Rough set and neural networks are both soft computing methods dealing with indefiniteness and incompleteness. They once played an important role in decision support, knowledge acquisition and so on. But there exist some limits when they are simply applied. On the other hand, because they are complementary, the integration of rough set and neural networks has become a hot topic in the domain of intelligent hybrid systems with great practical values and broad developing prospects for the designing of expert systems. The characteristics of rough set and neural networks are firstly analyzed in terms of epistemology and an overview of their integration and some comments are made in this paper. Furthermore, some problems concerning further research are presented.\;


Spectral reflectance properties of deciduous oak-hickory forests covering the eastern half of the Rolla Quadrangle were examined using Thematic Mapper (TM) data acquired in August and December, 1982 and Airborne Imaging Spectrometer (AIS) data acquired in August, 1985. For the TM data distinctly high relative reflectance values (greater than 0.3) in the near infrared (Band 4, 0.73 to 0.94 micrometers) correspond to regions characterized by xeric (dry) forests that overlie soils with low water retention capacities. These soils are derived primarily from rhyolites. More mesic forests characterized by lower TM band 4 relative reflectances are associated with soils of higher retention capacities derived predominately from non-cherty carbonates. The major factors affecting canopy reflectance appear to be the leaf area index (LAI) and leaf optical properties. The Suits canopy reflectance model predicts the relative reflectance values for the xeric canopies. The mesic canopy reflectance is less well matched and incorporation of canopy shadowing caused by the irregular nature of the mesic canopy may be necessary. Preliminary examination of high spectral resolution AIS data acquired in August of 1985 reveals no more information than found in the broad band TM data.


As autonomous vehicles loom as reality, and the vehicle communication starts to be enforced by law from 2020, protecting vulnerable road users (VRUs) using vehicle communication is receiving attention. The current vehicle-to-pedestrian (V2P) communication as stipulated by the standards such as SAE J2735 implies that it is the vehicles that take the responsibility for VRU protection. User devices are essentially beacons that transmit Personal Safety Messages (PSMs), and upon receiving PSMs, the drivers (or autonomous vehicles) take necessary measures to protect them. We, however, believe that the road users also need information about nearby vehicles to protect themselves from dangerous situations. Using other technologies than the standard Dedicated Short Range Communication (DSRC), there have been existing works for VRU protection. They use Wi-Fi or Wi-Fi Direct as replacements of DSRC. An automaker tested DSRC for VRU protection, but no technical detail has been presented. An important issue with the existing VRU protection proposals is that they are fraught with false alarms, which lowers the utility of the whole idea. Although one can come up with a highly precise collision prediction model, any such model will generate a huge number of false alarms, especially in urban environments. For example, if a pedestrian walks along a sidewalk well protected from the driveway, all passing vehicles will generate an alert to the pedestrian and vice versa. So our approach instead provides intuitive visual cues to the smartphone user looking at the screen, so that they can use their discretion to determine the level of danger for themselves.


There is an upsurge of crave for ethical practices and corporate social responsibility in both policy and actions of business organizations in recent times by society and social administrators globally. This is indicative of how crucial the subject is to the very existence of mankind and the universe as a whole and calls for a further assessment of the correlation between the concept and corporate bodies. Our write-up discusses the position of corporate social responsibility in relation to core business functions of companies and whether it has an influence on the growth of organizations. Social commentators and society unambiguously agree that the main causative factors for social problems like global warming, epidemics, wild fires, flooding and environmental degradation are the repercussions of organizational activities and therefore expect that organizations should be at the fore-front in the effort to combat these multifaceted issues. Companies have however maintained the view that corporate social responsibility is not relevant to their main mandate and only see it as a favor done to society. Our study debunks this misconception and demonstrate that the place of corporate social responsibility and ethical practices in business organizations is not just a philanthropic phenomenon but has relevance to core business functions and impacts on performance and growth. Our study also discovered that going beyond ethics in the operations of a company to engage in direct community development activities increases the effect of social responsibility on the fortunes of the company. Keywords: Corporate Social Responsibility; Growth; Corporate Responsiveness; Corporate Ethics; Philanthropic Phenomenon


An inverse emulsion radical reaction was adopted to prepare poly(vinyl alcohol) (PVA)-based microgels that contained titanium oxide (TiO2) or TiO2/Fe3O4, and the obtained microgels were applied to catalyze the degradation of methyl orange. First, well-defined PVA was used to synthesize a PVA-based macromonomer (PVAM) that contained carbon–carbon double bonds of tunable contents. Then, the composite microgels were prepared via the cross-linking reaction between PVAM and acrylic acid in the presence of TiO2 or TiO2/Fe3O4. Thermogravimetric analysis (TGA) and scanning electron microscope observation confirmed that the inorganic nanoparticles were well encapsulated within the microgels. TGA results showed that the loading efficiency of TiO2 was able to be controlled by varying the structure of PVAM. It was found that the microgels can efficiently catalyze the degradation of methyl orange. Moreover, the composite microgels possessed controllable and returnable catalysis ability. In addition, the separation of the composite microgels from aqueous solution could be quite easily accomplished by incorporating magnetic particles. POLYM. COMPOS., 2015. © 2015 Society of Plastics Engineers


Objective To observe the influence of comprehensive nursing intervention on coping style and life quality of COPD disease patients.Methods A total of 60 stable COPD patients were randomly divided into two groups, the control group was given conventional nursing, the observation group was given comprehensive nursing intervention including cognition intervention, behavior intervention and social support based on the control group, two groups were compared with uncertainty in illness, hope level and life quality.Results 3 month later, disease uncertainty score of unknown, lack of information, complexity in the observation group were lower than those in the control group, the reality and a positive attitude of the future, take positive action and hope were higher than those in the control group, life quality score in the body pain, social function mental health and so on were higher than those in the control group, with statistically significant (P〈0.05) .Conclusions The comprehensive nursing intervention can fully meet the needs of COPD patients, reduce the uncertainty in illness, and im-prove the hope level and life quality.

Key words:
COPD; Comprehensive nursing; COPD; Uncertainty in illness; Hope level


This study examined the nexus among oil price, exchange rate and stock market performance, using the VAR based technique. The Johansen cointegration test revealed the absence of long-run relationship among the variables. The Granger causality tests showed a unidirectional relationship running from crude oil price to shares and bidirectional relationship between crude oil price and exchange rate. Shocks to crude oil market had a positive impact on shares in the rst two periods, but very minimal beyond these periods. However, a one standard deviation innovation to exchange rate had negative impact on shares, implying that exchange rate instability may bring about uncertainty in the stock market. In most cases, each variable's own shocks are the major drivers of whatever movements observed in the respective trends in the variable. Findings from the estimations using the volatility series also mimic the results from the return series. The ndings imply that there are inherent structural or institutional rigidity in the transmission mechanism of oil price and exchange rate developments to the stock market.


For a long time,the 'self-sufficiency' has been the main theme in planning and designing the community living facilities,which leads to the neglecting of 'location'.Residential facilities based on the 'thousand people requirements' have their limitations in view of the construction.Through surveys of three communities of different locations,this paper analyzes the locational differences in the use of facilities.Based on the analysis,the paper proposes some coping tactics to create a dynamic 'self-sufficiency' in the planning of community facilities,to fully understand community location,and to incorporate the community facilities construction into the open urban systems.The study of the location of living facilities is of theoretical significance and practical value for the sustainable development of urban communities.


"But It Is Not So Among You": Echoes of Power in Mark 10:32-45, by Alberto de Mingo Kaminouchi. JSNTSup 249. London: TT 9:31; 10:33-34); the disciples fail to understand the prophecy (8:32; 9:32; 10:35-37); their failure prompts Jesus to teach about discipleship (8:34-9:1; 9:35; 10:41-45). Kaminouchi concludes by applying his findings to the ethics of the Roman Catholic Church's hierarchical structure of governance. This section, while interesting and relevant given the scandals that have beset that denomination, is the study's least satisfying piece. First, Kaminouchi's discussion of the issue is too brief to make an effective contribution to the dialogue about the appropriate delegation of authority within Roman Catholicism and seems out of place with the exegetical focus that is the book's raison d'etre. Second, his vision is parochial and contrary to his stated objective "to provide a critique of the misuse of the language of power and service in both academe and the church" (p. …


To determine the biological activity of Rhodiola rosea, the protein expression of iNOS and proinflammatory cytokines was measured after the activation of murine microglial BV2 cells by LPS under the exposure of constituents of Rhodiola rosea: crude extract, rosin, rosarin, and salidroside (each 1–50 μg/mL). The LPS-induced expression of iNOS and cytokines in BV2 cells was suppressed by the constituents of Rhodiola rosea in a concentration-dependent manner. Also the expression of the proinflammatory factors iNOS, IL-1β, and TNF-α in the kidney and prefrontal cortex of brain in mice was suppressed by the oral administration of Rhodiola rosea crude extract (500 mg/kg). To determine the neuroprotective effect of constituents of Rhodiola rosea, neuronal cells were activated by L-glutamate, and neurotoxicity was analyzed. The L-glutamate-induced neurotoxicity was suppressed by the treatment with rosin but not by rosarin. The level of phosphorylated MAPK, pJNK, and pp38 was increased by L-glutamate treatment but decreased by the treatment with rosin and salidroside. These results indicate that Rhodiola rosea may have therapeutic potential for the treatment of inflammation and neurodegenerative disease.


The purpose of this paper is to ask whether North Carolina public service lawyers and judges believe that their judicial districts perform with maximum efficiency or whether there could be functional improvement with leadership and management training for system leaders, and with the perceived need of such training, as articulated by these professionals, what a general training model might look like. A brief examination of the institutionally provided leadership and management training offered to system leaders shows sparse resources are expended to develop leaders and train them so that they have the skills to direct individual organizations and change the legal, institutional culture that exists in this justice system. Research shows that leadership and management training of justice system personnel would allow them to be adaptive to the needs of society and better able to effectively, efficiently use scarce resources allocated to the system by the North Carolina Legislature. * Resident Superior Court Judge, 14 Judicial District of North Carolina


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The most prominent recent attack on compatibilism about determinism and moral responsibility is the so-called manipulation argument, which presents an allegedly responsibility-undermining manipulation case and then points out that the relevant facts of that case are no different from the facts that obtain in an ordinary deterministic world. In a recent article in this journal, however, Matt King presents a dilemma for proponents of this argument, according to which the argument either leads to a dialectical stalemate or else is dialectically infelicitous. In this article I clarify the structure of the manipulation argument and construct a response to King's dilemma.


World Youth Day that will take place in Krakow in 2016 offers all of us challenges and opportunities. Opportunities for a spiritual awakening of the Church in Poland and a pastoral challenge that should unify everyone: bishops, priests, catechists, parishes, evangelicaland prayer communities throughout Poland and the world, and of course, young people. The World Youth Day is not a simple event, but rather an action of authentic and living faith. It began in 1984 by Saint Pope John Paul II when he presented to young peoplea challenge: a pilgrimage across cities and continents. And in joining that pilgrimage, young people, not only change themselves, but also contribute to a spiritual renewal in their local churches throughout the world. The core message of spiritual preparation for the WYDin Poland is the Beatitudes – the Eight Blessings – that Pope Francis proposed for us to reflect upon. The World Youth Day in 2016, and the preceding period of preparation, will be a huge spiritual retreat for all Poland. The expected fruit of this international encounter will be a new dynamism for Evangelisation.