MnO 2-Doped Polyaniline/Poly (Vinyl alcohol) thin films were prepared chemical oxidative polymerization, us ing microwave oven technique on glass substrate. These thin films prep ared by using Analytical Reagent grade solutions of Polyaniline, Poly (Vinyl alcohol), MnO 2, primary dopant hydrochloric acid are mixed in stoic hiometric proportion. The solutions were kept in mi crowave for 10 sec then oxides with ammonium peroxydisulphate o xidant, then after kept in water bath to obtain the uniform thin films. Films were dries it in air medium for an hour. The electrical and gas sensing properties of these films were inve stigated. MnO 2, Doped Polyaniline/Poly(Vinyl alcohol) thin films showed better ammonia and trimethyl ammine vapour respons e as compared to undoped Polyaniline / Poly (Vinyl alcohol) thin films. The gas response was observed to be increased with the ir stoichiometric composition of films.


Abstract : Agenda: *Introduction *Tools that Focus on Doing Things Right -Lean Thinking -Just-In-Time Planning -Six Sigma *Tools that Focus on Doing the Right Things -Engineering Design Process Thinking -Just-In-Case Planning -Simulation *A Yin-Yang Approach to Better *Conclusions


Background: Lumbar disc herniation presents a common compliant with numerous procedure being carry out in patients with interactable pain or neurological deficits. Conventional lumbar microdiscectomy involves substantial excision of disc material form the intervertebral disc space to prevent herniation. However, in many cases recurrence disc herniation is unavoidable. Sequesterectomy in cases of herniated lumbar discs has been reported as an alternative to standard microdiscectomy. Materials and Methods: In this study the clinical records and the main questionnaires of 107 patients were analyzed and compared with literature. Results: Preliminary results of a prospective randomized study in patients with lumbar disc herniation indicated equal recurrence disc rates and lesser reherniation in which patients are selected according to well defined criteria, which is largely depended on the competence of the annulus or posterior longitudinal ligament. Conclusion: There is tendency to superior clinical outcome in patients undergoing sequesterectomy. Microscopic sequesterectomy is more successful with lesser operating time with fewer intraoperative complications. Normal 0 false false false EN-US X-NONE AR-SA


Coal dust harness is an important research subject for coal handling port, so it is urgent to develop prevent frostbite water-supply and sprinkle system for winter dust-removing. The solution of moving trough + GPS positioning + automatic control water supply has been put forward by Qinhuangdao Port. The plan design, main implementing contain and system composition are introduced. This water-supply system has been implemented overall for stocker of Qinhuangdao Port Coal Phase 4, which has got good effect.


After searching the secondary generation FLX454 latex transcriptome database,the full length cDNA of a Hevea RAN GTPase(named as HbRAN1,GenBank accession: KC577150) was cloned.The full-length cDNA of HbRAN1 was first obtained from latex of H.brasiliensis,which is 969 bp long,encodes a protein of 25.11 ku(221aa) and contains the typical domains of Ran GTPases.At the amino-acid sequence level,HbRAN1 exhibits high homology to RcRAN1,NtRAN1,OsRAN1,TaRAN1 and AtRAN1.By Real-time RT-PCR analysis,the transcription level of HbRAN1 was regulated by tapping treatment,wounding,high temperature,chilling,drought stresses and ethylene.In addition,HbRAN1 showed obviously higher expression level in TPD(Tapping Panel Dryness) trees than that in healthy rubber trees.However,its expression did not affect by other hormones(SA、 GA、 JA、 ABA、 CTK and 2,4-D).The results suggested the HbRAN1 was one typical RAN member of small GTPase superfamily,and was implicated in stress-responses in Hevea tree,which may serve as a target gene for Hevea molecular breeding.


Thomas Ross (bap. 1620-75) was the first to translate Silius Italicus' epic poem Punica into English. The first edition of The Second Punick War Between Hannibal, and the Romanes: The whole Seventeen Books, Englished from the Latine of Silius Italicus: With A Continuation from the Triumph of Scipio, To the Death of Hannibal appeared in 1661. A second and slightly altered edition was issued in 1672. Ross, an active participant in the intrigues plotted to restore the monarchy, was part of Charles's entourage when the latter established his court in Bruges in 1656. His translation is amongst other things a royalist response to the English Civil Wars. Ross's choice of source text, his dedicatory epistle to Charles II written in Bruges in the fall of 1657, his prefatory poem 'To the King' as well as his collaboration with the Antwerp graphic artist Jozef Lamorlet (1626-c.1681), mark this long-neglected epic as a product of the English involvement in intellectual life on the continent in the mid-seventeenth century. With each of its numerous 'dramatic' engravings dedicated to distinguished supporters of the royal cause, The Second Punick War moreover illustrates how word and image were made to serve monarchic ideology.


Each part variety of steam turbine thermal system can cause different infections on unit's economic. This paper took the 350MW unit as a example, equivalent enthalpy drop was adopted for analyzing unit's economic when part changes took place in makeup water system、plant using steam、system of deoxygenizer standby steam fountainhead、exclude dirt and its use system and recycle system. This work may provide evidences for composing heat system with exactitude and reasonable as well as guiding operation of heat system.


The author, a Frenchman confesses about his obsession with the Russian writer Gorky, and how he influenced not his work but his life. The greatness of Gorky which made him exceptional is highlighted.


The telecommunications revolution has increased the options and capabilities available for communications-based protection of transmission lines. To improve tripping speeds on long and short lines, protection engineers can select from a host of media, protocols, and logic schemes. The question to address is what communications scheme is best for which circumstances. This paper begins by establishing performance baselines of protection scheme operating times measured in event reports for a variety of in-service lines. It includes various successful systems and takes into account all of the elements that must be addressed when engineering a protection scheme, such as relay pickup time, communications interface and latency, coordinating time delays, and sequential tripping times. These in-service schemes are compared with laboratory tests of new systems, using radio and fiber-optic communications with serial and Ethernet protocols. Methods of optimizing different systems are tested and evaluated; the final results are tabulated and compared. No single scheme is best for all circumstances. With comparison data, the protection engineer can select the best options to improve the overall power system performance. Recognizing the strengths and weaknesses of different schemes assists the engineer in addressing new situations. Comparing laboratory tests and in-service performance provides a tool for evaluating a transition to new technologies.


Fast magnetization precession is observed in L10-FePt alloy epitaxial thin films excited and detected by all-optical means. The precession frequency varies from 45 to 65 GHz depending on the applied magnetic field strength and direction, which can be explained by a uniform precession model taking account of first- and second-order uniaxial magnetic anisotropy. The lowest effective Gilbert damping constant has a minimum value of 0.055, which is about half that in Co/Pt multilayers and is comparable to Ni/Co multilayers with perpendicular magnetic anisotropy.


Benefiting from good solubility of metal halide perovskites, low-temperature solution processes (including one- and two-step spin-coating) have become the most common approach for perovskite solar cells (PSCs). However, one confusing issue is that what are specifically effective strategies for the one-step process may not be applicable for the two-step process, and vice versa. Herein, the PSCs with the same perovskite composition and device configuration were prepared by one- and two-step processes, respectively. The results indicated that high performance PSCs with comparable power conversion efficiency over 22% were achieved by both methods, while the detailed photovoltaic parameters varied greatly depending on the one- or two-step process. Compared to the one-step counterpart, the two-step processed PSCs exhibit lower open-circuit voltage and fill factor, but superior short-circuit current, which was in-depth interpreted in terms of the crystalline growth mode, optical properties, defect types, and carrier transport mechanisms related to a perovskite film surface (including a top and a bottom surface). Understanding the root cause for such differences would be central toward identifying what is really crucial for further producing high performance PSCs.


A new common Geo-data format known as the Geography Markup Language (GML) has been specified by OGC (Open Geospatial Consortium, Inc.) through a unique marriage of the W3C's (World Wide Web Consortium's) Extensible Markup Language (XML). GML maintains a strong separation between presentation and content. To make a map with GML data, GML geographical content must be styled into a suitable graphical presentation that can be interpreted in a Web browser. A suite of new technologies such as XML, SVG, and DOM create a new perspective for it. The Scalable Vector Graphics (SVG) is a new XML-based graphic format for defining 2D graphics, including vector and raster format, for the web and other applications. This paper shows how the Geo-data to be stored and transferred in GML and visualized in SVG, as well as converting from GML to SVG via Extensible Stylesheet Language Transformations (XSLT) and how to make the SVG graphic dynamic with Hypertext Markup Language (HTML) and Document Object Model (DOM). KeywordsGML; SVG; XSLT; DOM; Internet


Through the comparison of different synthesis process routes of telmisartan(TMST),the work had determined a process route of synthesizing telmisartan by three steps of condensation,hydrolysis and refinement,which had the starting material of intermediate 2-n-propyl-4-methyl-6-(1-methylbenzimidazole-2-yl)-benzimidazole (i.e.the bis-benzoimidazole) and 4'-bromoethybiphenyl-2-cyano.The total yield of the three step was 70.2%.The intermediate in this process route was stable and the after processing was simple and convenient.Moreover,the other main material 4'-bromoethybiphenyl-2-cyano was cheap,less adjuvant material assisted,high yield and more environmentally friendly.Thus,it was more suitable for industrialized production.Additionally,the process had been applied into practical production in Yichang Tianren Pharmaceutical Corporation Limited.


shown in LAD (Video 1). Troponin I levels increased significantly and the transthoracic echocardiography showed wall motion abnormalities in anterior, apical and septal segments of left ventricle. Myocardial bridges consist of muscle fiber bundles lining an epicardial coronary artery for a variable distance. They are found in 10% of all coronary angiography procedures. The vessel wall underneath the muscular bridge is usually thin and free from degenerative atherosclerotic changes. A coronary stenosis caused by a short muscular bridge is considered critical when greater than 75%. Bridging of the epicardial coronary arteries has been described only in association with the left ventricular myocardium and most commonly with the LAD. Especially myocardial bridges in both LAD and diagonal branches are very rare. In our case, the patient has myocardial bridges in both LAD and its diagonal branch. Although myocardial bridges are usually associated with a benign prognosis, being in many cases asymptomatic and only found by chance, their presence has also been considered a cause of angina, malignant arrhythmia, myocardial infarction and sudden death. Therefore when patients has not any atherosclerotic risk factors and applied with acute coronary syndromes, percutaneous intervention may be prefer as reperfusion strategy as we did. We evaluated that the reasons of the myocardial infarction were the insufficient blood flow through the bridging arteries and the micro-thromboembolism from narrowing vessel segments. Other mechanisms such as neurohumoral or metabolic, may be played role in this case. Further studies need in this subject.


463 Background: Cancer patients are frequent users of the emergency department (ED); preventing such visits is important for improving the quality of cancer care and decreasing health care system burden. This study describes oncology ED visits at a single institution, and seeks to define a novel definition of potentially preventable ED visits (PPEDs), particularly considering novel cancer therapies. It also uses machine learning (ML) to create early models to predict patients at highest risk of PPEDs. Methods: A retrospective study of ED visits by oncology patients between April 1st, 2019 and April 1st, 2021 at a single academic institution was completed. PPEDs were defined as ED visits resulting in discharge from the ED or an admission of less than 48 hours. PPEDs versus non-PPEDs were evaluated using descriptive statistics, logistic regression, and machine learning (ML) modelling. Results: 17% of cancer patients (n=6,689) had 13,415 ED visits during the study period. PPEDs differed in characteristics from non-PPEDs. Stage 1-3 patients with breast cancer, and those on IV systemic therapy were more likely to have PPEDs.Logistic regression models of pre-ED visit variables showed that stage, distance, and neoadjuvant systemic therapy were associated with PPEDs. Logistic regression of ED visit-related variables revealed that genitourinary, eye, or skin-related diagnoses were associated with PPEDs. The highest-performing ML model scored an AUC of 0.819, and combined pre-ED visit and ED visit related variables; stage 1-3 breast cancer patients, all IV chemotherapy patients, and stage 4 patients living within 15km of the ED, or with GI, oral or female gynecologic cancers were associated with PPEDs. ED diagnoses of "cancer" and MSK issues were associated with PPEDs. For those patients on IV systemic therapy specifically, having breast cancer, having a palliative consult within 60 days of the ED visit, or presenting with ED diagnoses of toxicities from therapy or blood disorders, pain, or rash were associated with PPEDs. Conclusions: Our novel definition of PPEDs versus non-PPEDs appears reasonable, and using machine learning has helped to describe groups of patients at highest likelihood of such visits at our institution. Future work to validate and advance these models into clinical prediction tools and algorithms could help proactively target high risk patients, and ideally decrease preventable ED visits in oncology.


Due to a rapidly globalizing world, there has been a recent resurgence in the demand for university graduates entering the workforce who understand and utilize spoken English rhetorical strategies and techniques. These rhetorical skills are necessary in a wide range of fields (e.g., advertising, communication, international relations, politics, psychology, etc.), yet rhetoric rarely features in EFL or ESL curriculums. With the Ministry of Education, Culture, Sports, Science and Technology (MEXT) in Japan emphasizing the need for English education to specifically foster the development of oral communication skills through the Global Human Resources (GHR) project (2018), there is a definite need for integrating instruction on English rhetorical strategies and techniques into the curricula of higher education. However, explicit rhetorical instruction in EFL and ESL curriculums in Japan almost exclusively focuses on written genres, such as essay writing. The core research question framing this exploratory study is: How prominent is instruction on rhetoric in Japanese university English oral communication courses? This qualitative study firstly examines if rhetoric-based instruction is addressed in a sample of English language oral communication textbooks, before documenting the language learning experiences of ten Japanese university students. An amalgamation of the data reveals a dearth of explicit rhetoric-based instruction in Japanese university English language oral communication courses. The implications of this finding are discussed, and suggestions are then proffered on how to better equip Japanese university graduates with practical English language rhetorical tools so that they may play a more active role in the globalizing world.


Allium cepa is used as a condiment and reduction of yield due to infectious diseases is a major economical constraint. The present study was aimed at isolation and identification of fungal pathogens associated with damping-off disease of onion in Sri Lanka. Trichoderma spp. present in the soil of the same onion fields were isolated with a view to evaluating them as possible biocontrol agents of damping-off pathogen(s). The diseased seedlings were collected from fifty-five onion fields in Matale and Anuradhapura districts during the yala season. Soil collected from the same onion fields and soil fungi isolated using the Warcup method. Fusarium sp. isolated from diseased seedlings was confirmed to be the causative agent of damping-off disease of big onions by following Koch's postulates. The pathogenic Fusarium sp. was identified as Fusarium solani based on the similarity matches of the Internal Transcribed Spacer region using Basic Local Alignment Search Tool. Two Trichoderma spp. showing significantly high (p ≤0.05) reduction of growth of F. solani in dual culture assay, higher sporulation capacity and growth rates were identified as T. asperellum (Tr.3) and T. virens (Tr.1). Polymerase Chain Reaction (PCR) using two primer pairs i.e. ITS 1 and ITS 4, FR 1 and NS 1 were used to characterize the seven Trichoderma spp. while ITS 1 and ITS 4 were used to characterize Fusarium spp. Although a lesser degree of polymorphism was detected using these primers, the random amplified polymorphic DNA analysis had the ability to differentiate T. asperellum, T. virens and F. solani. The capability of two Trichoderma spp. to suppress F. solani is through formation of loops and coils and attachment of hyphal tips. They also had the ability to produce Chitinase and volatile metabolites that controlled the growth of F. solani.


This paper provides a brief summary of the literature on foreign direct investment and gender equity as well as an empirical study based on the Moroccan case. The review of empirical literature on the impact of foreign direct investment on gender equity is rather mixed. Foreign direct investment certainly contributes to the feminization of work in developing countries,mainly by expanding labour-intensive, largely export-oriented industries. However, evidence exists that shows women losing their jobs to more qualified men as industries upgrade. While empirical studies indicate a positive impact of foreign direct investment on women's wages, it seems less likely that this will result in a closing of the gender wage gap. Our case study consists of the analysis of the impact of foreign direct investment on female employment in two important sectors:manufacturing and services (call centers specifically). The following results emerge: – Although Morocco has become more attractive, its capacity to draw more foreign direct investment is still insufficient, due mainly to its small market, the lack of human resources, and persistent governance problems. Foreign direct investment has certainly contributed to the feminization of employment, especially through the expansion of export-oriented industries such as electronics, automotive components and garment. However, female employment is limited to assembly tasks and women are confined to low level positions into industrial hierarchy. Due to their higher productivity and their organizational know-how, multinational subsidiaries tend to distribute high salaries in comparison with their local counterparts. Given the wage gap within foreign firms and the confinement of women in low positions, it is less likely that these better salaries benefit to them. – It is clear that the expansion of call centers in Morocco open up new opportunities and better pay for women.Information technology enabled services seem to have given women confidence and social empowerment. However? Some areas of concern emerge : – the repetitive nature of most of these jobs which may lead to the "burnout syndrome" ; – cases of stress and anxiety that some women face from pressure of having to be constantly controlled by supervisors assisted with information technology and sophisticated management practices ; – reflecting the gendered composition of the industry, women are concentrated in low routinized, clerical related jobs ; – work in call centers reinforces stereotypical perceptions of skill and feminity because of the presumed communication and social abilities of women ; – most call center jobs are "footloose" in nature and there is growing competition from other countries in the Mediterranean and from Africa to attract these jobs.


We examine the inverse cascade of kinetic energy to large scales in rotating stratified turbulence as occurs in the oceans and in the atmosphere, while varying the relative frequency of gravity to inertial waves, N/f. Using direct numerical simulations with grid resolutions up to 10243 points, we find that the transfer of energy from three-dimensional to two-dimensional modes is most efficient in the range 1/2 ⩽ N/f ⩽ 2, in which resonances disappear. In this range, the cascade is faster than in the purely rotating case, and thus the interplay between rotation and stratification helps creating large-scale structures. The ensuing inverse cascade follows a −5/3 spectral law with an approximately constant flux. This inverse cascade becomes negligible when stratification is dominant.


We study tensor products of a $C_0 (X)$-algebra $A$ and a $C_0 (Y)$-algebra $B$, and analyse the structure of their minimal tensor product $A \otimes B$ as a $C_0 (X \times Y)$-algebra. We show that when $A$ and $B$ define continuous C$^{\ast}$-bundles, that continuity of the bundle arising from the $C_0 (X \times Y)$-algebra $A \otimes B$ is a strictly weaker property than continuity of the `fibrewise tensor products' studied by Kirchberg and Wassermann. For a fixed quasi-standard C$^{\ast}$-algebra $A$, we show that $A \otimes B$ is quasi-standard for all quasi-standard $B$ precisely when $A$ is exact, and exhibit some related equivalences.


This report summarises the results of a two year project funded by the Ministry of Justice, evaluating the impact of regulatory and training regimes on the front line experiences of solicitors and advice agency staff involved in the delivery of publicly funded legal advice. The findings shed light on the impact of contractual regulation on the organization and objectives of private firms and voluntary organizations, and rpovide insight into the nature of work-based learning.


Beam driven stable equilibria for a conceptual reactor, Demo-CREST, which was designed for early demonstration of electric power generation, has been investigated. Considering current profiles driven by neutral beams, the attainable normalized beta βN with a stabilization wall is about 3.4 with a normal shear (NS). With reversed shear (RS), a higher βN is attainable. The stable equilibria up to 4.0 can be sustained by a couple of On-and Off-axis beams. In the range of 1.9 20 keV is allowable.


An analytical method was developed to study the wave diffraction effects on arc-shaped floating porous breakwaters.The breakwater was assumed to be rigid,thin,vertical,immovable and located in water of constant depth.The fluid domain was divided into two regions by imaginary interface.The velocity potential in each region was expanded by eigenfunctions.By satisfying the continuity of pressure and normal velocity across the imaginary fluid interface,a set of linear algebraic equations could be obtained to determine the unknown coefficients for eigenfunctions.Numerical results,in the form of contour maps of the relative wave amplitude around the breakwater,were presented for a range of wave and breakwater parameters.Results show that the sheltering effects on the arc-shaped floating porous breakwater are closely relative to the incident wavelength,the draft and the porosity of the breakwater.


ABSTRACT Academic burnout and engagement are critical factors in student success, school attendance and dropout. It is important to determine the variables associated with burnout and engagement to develop university students and their competencies. Therefore, the current study aims to elucidate the association of morningness-eveningness preferences, average sleep length (ASL) and social jetlag (SJL) with burnout and engagement in university students. The sample was composed of 270 university students. The composite scale of morningness (CSM), the Maslach burnout inventory-student scale, student engagement scale and a questionnaire were utilized. CSM total score was found to correlate with both burnout and engagement sub-domains significantly. In addition, CSM total score was a significant predictor in all burnout and engagement models. ASL was a significant predictor of exhaustion and cynicism while SJL was significant predictor of efficacy. Both ASL and SJL were significant predictors of silent in-class behaviours sub-domain of engagement. In sum, CSM total score was found to be the most significant predictor of both burnout and engagement compared to other study variables. Considering the relationships of CSM total score with burnout and engagement sub-dimensions, eveningness can be treated as an important risk factor for burnout and engagement in the context of university students.


In this paper, we have introduced the notions of strong and weak convergences in 2-probabilistic normed spaces (2-PN spaces) and established some of its properties. Later, we have de ned the strong and weak boundedness of a linear map between two 2-PN spaces and proved a necessary and su cient condition for the linear map between two 2-PN spaces to be strongly and weakly bounded.


In this short analysis of Catholic representations of St. Mary throughout the centuries as a breastfeeding mother, we see that this very popular image in early Christianity and the Middle Ages is banned after 1593 and replaced by a childlike virgin. Thereby the power attributed to Mary's milk, as the embodied transmission of the Holy Word in early Christianity, slowly dissipates. What once was holy is now abject, and this is linked to the more general sexualisation of the female body, and the ambivalence about feeding breasts in wider society.


Daniel Morris: Your Blackwell Manifesto is called Living with Theory (2008). A cunning title. It could mean a grudging acceptance, as in "OK, I'm an old school literature guy, but, I give in, I'll learn to apply bits and pieces of theory in my survey of canonical masters." Or, it could be a kind of virus, an affliction: "Darn, I've got this theory bug, but I'm learning to live with it." Or, and this is what I assume to be the Leitch approach: knowing theory has somehow changed or enabled or informed your daily life. Could you reflect on how you "live" with theory? Can you ever turn the "theory head" off and, to commercialize this conversation, "Just Do It"? You mention in your book how even your decision to wear a suit and tie to class is a meaningful, a theoretical, gesture, one that allows you to go undercover as a subversive "dangerous professor." What is it like for you "living with theory"? It must inform the way you read the paper in the morning, the food you eat, the way you watch TV, the car you drive, your interpersonal relations. I guess it could be described as a bit of a viral disease, this living with theory!


This paper presents an animation system that generates an animation from natural language texts such as movie scripts or stories. We also propose the framework of a motion database that stores many motion clips for various characters. When an input text is given, the system searches for an appropriate motion clip from the database for each verb in the input text. Temporal constraints between verbs are also extracted from the input text. The searched motion clips are scheduled based on these temporal constraints. In addition, when necessary, some automatic motions such as locomotion, taking an instrument, changing posture, and cooperative motions are searched from the database. An animation is then generated using an external motion synthesis system. Using our system, users can make use of existing motion clips. Moreover, because it takes natural language text as input, even novice users can use our system.


specimens from a bay near the town of Pocone, in thePantanal of Mato Grosso, Brazil. The observed diploid number was 2n = 34 chromosomes for both sexes and three distinctkatyotypic formulae were found, namely cytotype A (20m, 8sm, 6st, Fundamental Number/FN = 68; 6 males and 11 females),cytotype B (19m, 8sm, 6st, 1a, FN = 67; 8 males and 4 females) and cytotype C (18m, 8sm, 6st, 2a, FN = 66; a single male). NORs 'sanalyses showed that these regions were located in distinct sites on the NOR-bearing chromosome pair, according to cytotypes.Thus, in cytotype A, NORs were located in the terminal region of the short arm of the second metacentric chromosome pair; incytotype B, they were detected in the short arm of the metacentric chromosome and interstitially on the acrocentric chromosomeand, in cytotype C, NORs were observed in the interstitial region of the acrocentric chromosome pair. C-positive heterochromati cbands were adjacent to the rDNA sites in the corresponding chromosomes. Thus, the chromosomal polymorphism of


Photo-reduction of p-benzoquinone, 1,4-naphthoquinone, and their methyl- or chloro-derivatives has been investigated by means of CIDNP technique. Strongly polarized PMR signals due to unstable reaction intermediates, p-quinones, and hydroquinones were observed during the course of reaction. Structures of the unstable reaction intermediates, none of which accumulated as reaction products, were determined, their polarized PMR signals being compared with those of the unstable reaction intermediates resulting from the deuterated substrates. From these results, a reaction scheme for these photo-reduction was proposed.


Aim To observe effects of Sodium tanshinoneⅡA sulfonate(STS) on angiotensionⅡ(AngⅡ)-induced cardiomyocyte hypertrophy and the expression of phosphorylated extracellular signal-regulated kinase1/2 (p-ERK1/2). Methods In the primary culture of neonatal rat cardiomyocytes, as indexes of cardiomyocyte hypertrophy, the total protein was determined by coomassie brilliant blue and protein synthesis rate was measured by [3H]-Leucine incorporation. The expression of p-ERK1/2 was assessed using Western blot and fluorescence microscope. Results ① The total protein and protein synthesis rate stimulated by Ang Ⅱ(1 μmol·L-1)in the cardiomyocytes increased significantly in contrast to that of control; STS could effectively decrease the increased total protein level induced by Ang Ⅱand markedly inhibit synthesis of protein. ② AngⅡ(1 μmol·L-1) had the effect of promoting activation of ERK1/2 and then appeared in nucleus rapidly. The translocation process of ERK1/2 induced by AngⅡ was blocked distinctly by STS. ③ Cardiomyocyte pretreated with Ang Ⅱ(1 μmol·L-1)for 5 min, the p-ERK1/2 protein expression began to increase ,the peak effect was at 10 min. While pretreatment with STS(2, 10, 50 μmol·L-1) ,Ang Ⅱ-induced increase in p-ERK1/2 were inhibited evidently. ④ In pretreatment of cardiomyocyte with STS in different doses for 30 min, STS was found to be able to inhibit the expression of p-ERK1/2 stimulated by AngⅡ in a dose-dependent manner. Conclusions The results suggested that activation of ERK1/2 might play an important role in cardiomyocytes hypertrophy induced by Ang Ⅱ,and the anti-hypertrophic effect of STS on cardiomyocyte hypertrophy induced by AngⅡ might be associated to its inhibitory effect on ERK signaling pathway.


The distribution of charge states of ions of F19, Cl35, and Br79 emerging from thin carbon foils at energies of 10 to 40 Mev have been measured. Atomic charges of 7, 9, and 11 electron units for the three elements respectively are produced at 10 Mev with an intensity of greater than 15% of the incident beam. These results show that a tandem accelerator with 10 Mv on the terminal can deliver good ion beams at the following energies (the values in parentheses require two-stage stripping resulting in a further reduction in beam intensity by a factor of 5 to 10): 80 Mev (95 Mev) F19 ions, 100 Mev (125 Mev) Cl35 ions, and 120 Mev (160 Mev) Br79 ions. The measurements show that heavy ions from a tandem accelerator can be injected into a cyclotron and stripped to give appropriate magnetic rigidity for acceleration to very high energies; for example, a 90-in. diameter magnet with a field of 14 kilogauss will yield Cl or Br ions.


The structural and electronic properties of inclusion or interconnection between NT and PVC were studied by quantum semiepirical approximation method using (PM3) self-consistent ?eld molecular orbital method. The total structural energy, HOMO level energy, LUMO level energy, band gap?(E?_g ?=E?_HOMO-E_LUMO), and dipole moment of the compounds were calculated. Increasing the distance between NT and PVC led to decline the total energy difference which led to better interconnection between NT and PVC and vice versa when the distant is decreased. Therefore the more stable compound is f. The best electronic energies were obtained at the structures 3c and 3b in the first distance respectively. The dipole moments for all structures have the following trend: b> d > c > e > f > a> g.


This book assesses the magnitude of the effects of trade liberalisation on welfare and the environment in the context of a small open economy, and the degree to which these effects are influenced by environmental policy. It is expected that the results of this study will provide some direction for trade and environmental policies, and will help to fill part of the empirical vacuum in this field. These results will be widely applicable to open-market-based economies and to countries embarking on major liberalisation programs.


Anti-testosterone and anti-5 alpha-dihydrotestosterone antisera have been produced by pretreatment of mice with a cross-reacting steroid coupled to a copolymer of D-glutamic acid and D-lysine to inhibit production of cross-reacting antibodies before immunization with the specific steroid conjugated to a protein. 15 beta-Carboxyethylmercapto derivatives were used as haptens. The cross-reactivities of the anti-testosterone and anti-5 alpha-dihydrotestosterone antisera with 5 alpha-dihydrotestosterone and with testosterone were 0.49 and 13.5%, respectively.


Telomeres, the repetitive DNA elements at chromosome ends, are pivotal for maintenance of genome integrity. Previous studies from our group and others have highlighted the translational potential of tissue-based telomere length measurements to address the clinical challenge of improving diagnosis, individualized risk stratification, and accurate prognostication of different diseases. Here, we describe a high-throughput method that quantitates cell type-specific telomere lengths at a single cell level in archival tissues from patient cohorts for research on prognosis. This approach is based on telomere-specific fluorescence in situ hybridization (FISH) combined with multiplex immunostaining for cell type-specific antibodies, followed by semi-automated slide scanning and multi-channel acquisition of fluorescent images using the TissueFAXS Plus microscopy workstation and TissueQuest software (TissueGnostics). Here, we demonstrate that this method is sufficiently robust and reproducible to detect biologically significant differences in telomere lengths in archived tissues either on whole slides or sampled across tissue microarrays, which is essential when assessing prognosis in large patient cohorts.


Purpose – Information and communication technologies (ICTs) usage is one of the key elements in the competitive struggle and achieving a competitive advantage in the hotel industry. The main goal of this paper is to empirically analyse the existence of readiness to implement ICTs in a sight of the potential challenges which hotels face due to the lack of such technology in their business. Methodology – This article, through researching the attitudes of managers at the top, middle and operational management levels, analyses the readiness of the organizations in hotel industry to implement ICTs as well as the main opportunities and advantages of their application. The data were analysed by acting the methods of descriptive and inferential statistics in order to test the significance of the examination attitudes obtained from respondent. Findings – The obtained results indicate the importance of the readiness for companies in the hotel industry to apply ICT and the inclination for digital transformation of business. There is exigency to provide an insight into the state of readiness for the implementation of digital technologies in the hotel industry, as well as a proposal for the values that these actions result. Contribution – The main contributions of this paper are fulfilling the literature gap towards the mentioned research issue for the implementation of ICT in the hotel industry at the regional level and providing insight from the viewpoints of managers rather than from technology experts.


As one of the important documents which often consulted by people while studying the military system of the Ming Dynasty,the value of Zhang Tingyu`s Bing Zhi of Ming Shi can't be ignored.With regards to its practical value,it has kept important information of various fields of the military system of Ming Dynasty comprehensively and systematically.It is not only a commonly most used special "Zhi" and one of main documents specially easiest to obtain in the books market that moderns understand and study the military system of Ming Dynasty,but also a window of understanding of the scientific and technological development state in the Ming Dynasty.In respect to its compiling value,it has some advantages,including complete style,widely collection,detailed test precisely cut out,succinct language.As regards its historical data value,because it includes a large number of memorial to the throne that " Ming Shi Lu " and "Ming Hui Dian " didn`t record,it has unique historical data value.


pair, or a certain proportion of the brood, could not possibly be "protected. " Rabaud concludes "from the point of view of offense as well as that of defense, the mantid does not gain any evident advantage from its coloration. One should not forget that the term 'green' or the term 'brown' designate only the most divergent phases of color, . . . that the clear green mantid lives at a season when concolorous foliage is not plentiful, and the opportunity of playing the role of homochromy is seldom realized. The chances of realization are not more frequent for the brown mantids and for the same reason: the homochromy of Mantis religiosa pertains to the realm of legend" (p. 15). This is quite a different way of referring to the worth of protective coloration in Mantis religiosa from the "proved to the hilt" assertion of the text-book, but one, if we must choose between extremes, that according to the evidence presented is perhaps the more acceptable. Some one has said that the theories of to-day are the text-book facts of to-morrow, but that dictum fails in the very necessary admission that many theories never attain the status of facts. In so stating we have in mind the popular use of the term "fact," for dependable information. There is a meaning with dictionary sanction, however, that may be more consoling to the makers of text-books and that is-anything alleged. W. L. MCATEE BIOLOGICAL SURVEY, WASHINGTON, D. C.


As a result of economic reform commencing in 1978 in China, cultural beliefs of the Chinese business owners are changing. While much has been published concerning large and multinational businesses, there is a gap in knowledge of cultural beliefs of small and medium sized enterprises. To provide new knowledge, a survey on these smaller sized enterprises located throughout China was conducted in the summer of 2006. Respondents were selected from urban and rural areas, coastal and inland provinces and various industries to provide information on their opinions on how some of their cultural beliefs have changed from 1990 to present. Specific beliefs questioned include: Use of fengshui, Traditional Forbidden Activities, Company Naming Responsibility, Company Name Basis, Use of Numbers, Use of Physiognomy, and Prediction of a Company's Future. The importance of fengshui has risen over in the last sixteen years and certain traditional forbidden activities such as not turning over the fish while eating has remained important as a cultural belief Naming a company is important and the desirability of a good name is based on various factors. Use of numbers, physiognomy, and non-scientific methods for predicting the future success of companies are of lesser use. These aspects of culture are reviewed in consideration of the change from a planned economy to a market-based economy.


Excerpt] On behalf of the AFL-CIO, I am writing to urge you to support the inclusion of five important sourcing reforms in the FY 2012 Financial Sendees appropriations bill when conferees convene on this important issue.


The A–X fluorescence excitation spectrum of HCN has been recorded using 4‐wave mixing in Sr vapor as a tunable vacuum ultraviolet source. The excitation spectra are notable for the high signal to noise ratio, resolution (FWHM ∼0.3 cm−1) of nearly all previously blended lines, and accuracy of wavelength calibration (±0.03 cm−1). Measured lifetimes for the first three bending levels of the A state [τ(000)1=13±7 ns, τ(010)1=130±24 ns, and τ(020)1<2 ns] qualitatively confirm the results of Hsu, Smith, and Wallace [Chem. Phys. Lett. 111, 219 (1984)]. Stern–Volmer fluorescence quenching studies reported here yield a best fit quenching constant for the A(000)1 rotational levels of Kq =73/μs⋅Torr, which is similar to the quenching constant of the A(010)1 level (Kq =24.3±0.4/μs⋅Torr).


The application of braking systems with the lo-cation of the executive mechanism directly upon a bogie is a promising trend in domestic brake production and freight car manufacturing on the whole. In the paper a common circuit of a braking rod leverage with the location of cylinders 670V on the bogie of two-axle type 2 and type 3 (RSS 9246-2013) is considered. The investigation carried out in the work is a continuation of works connected with the updating of a braking system developed earlier.
 The aim of the work consists in the definition of cylinder rod outlet limits taking into account elastic deformation of all elements of leverage in accordance with the procedure developed and appraised earlier and also the definition of maximum possible thickness of a brake pad used for this circuit in operation. The rod outlet limits obtained will be standard as system transmission ratio is unified, and an elastic constituent will have minimum deviations from the value obtained and depend upon a specific execution of elements.
In this investigation there is used a 3D brake system model developed thoroughly that allows obtaining an elastic deformation value precise enough. Furthermore, data obtained allow defining a maximum operation outlet of rod of the braking cylinder 670V in the system analyzed during car motion on a long steep slope.
On the basis of the investigations carried out there are defined the limits of rod outlet (35…47mm) for the developed common brake system with cylinders 670V that allows using brake pads of maximum width (65+5mm) used in railway freight rolling-stock of the RF. The maximum operation value of rod outlet is obtained during car motion on a steep long slope (63mm) which does not exceed a working stroke of a cylinder (100mm).


Aging was normal process of human living. Hypophysial fossa as a protector of hypophysial gland, in aging process hypophysial gland was atrophy. For this phenomena happened in older age, what will happen through the hypophysial fossa?. Collaborative research had done between anatomy laboratory Medical Faculty of Airlangga University and anatomy laboratory Medical Faculty of Wijaya Kusuma Surabaya University, subject of research was cadavers from both medical faculty. The cadavers were majority javanese and from lower class of social community, such as beggar, poor, and unidentified person which donated to medical faculty for studying of anatomy desection. The cadavers age was exactly unknown, so to identify the age of cadavers by using an anthropologist method of age determinate. In this research, the anthropologist method to determinate age was observation of cadaver's calvaria suture and surface molar teeth damage as a support method. The depth of hypophysial fossa was measured by digital caliper which depth measuring face located at horisontally line bethween tuberculum sellae and dorsum sellae, therefore depth measuring blade of digital caliper can reach bottom of hypophysial fossa accuratelly. The result of research showed that depth of human hypophysial fossa due to aging process was positive correlation, significant at 0.01 level of two-tailed. That condition were happens as a reflection of aging process in human during alive, in which paralel to aging the increase of the aging the so that the impact begins clear, particularly the severity of atheroscelerotic process there were that of to the blood vessels of the vascularisation to hypophysial fossa. This research as a foundation to next research which explore causes of changing the hypophysial fossa depth, which could be early sign of aging process so human can reach optimum quality of aging.


Enzymes Immobilization onto different types of substrate could be helpful in various applications of biomedical devices and biosensors. Enzyme activity and stability could be affected by support and method of immobilization. In this study, the silver metal foam was successfully synthesized by soft-shell method and then was coated with silica. Then, glucose oxidase (GOx) was immobilized on non-coated and silica-coated silver metal foam and removal of malachite green was investigated. Fourier Transform Infrared Spectroscopy (FT-IR) and scanning electron microscopy (SEM) results confirmed that the enzyme was attached to support surface. The maximum immobilized enzyme activity was about 118.980 U/grSupport at 40ᵒC. The removal of malachite green showed the indirect relation with dye concentration confirmed by decolorization assay. The increasing activity, thermal stability, and reusability of immobilized glucose oxidase onto the silver metal foam in comparison to free enzyme introduce the capability of the biological system for removal of malachite green in the industry.


Next Generation Networks demand quick access of data from all around the globe, thus populating backbone network with heavy data traffic. All-optical network is capable to handle such ever increasing load with reduced complexity. In this scheme the processing is done completely in optical domain employing pure optical devices. The optical packet includes the control information (header) and data bits (payload). Semiconductor Optical Amplifier and optical couplers are employed for header extraction. Header and routing table information is converted in pulse Position format for ease of processing. This provides high speed processing of optical packet with less optical complexity and reduced routing table. Then it concentrate on the packet forwarding technique, which includes the optical pulse matching logic, and then followed by the simulation part, which shows the implementation in MATLAB Simulink. Finally, concludes the topic with future scope for optical processing in high speed world.


Based on the latest archaeological materials,the paper shows that the rock painting in Qinghai about yaks richly reflected the district features for its special natural environment,and the painting also showed the feature that the painting about animals and other rock paintings around influenced and integrated with each other.


Simple Summary The alternative splicing (AS) process is highly relevant, affecting most of the hallmarks of cancer, such as proliferation, angiogenesis, and metastasis. Our study evaluated alterations in 304 splicing-related genes and their prognosis value in breast cancer patients. Amplifications in CLNS1A, LSM1, and ILF2 genes in luminal patients were significantly associated with poor outcome. Downregulation of these genes in luminal cell lines showed an antiproliferative effect. Pharmacological modulation of transcription and RNA regulation is key for the optimal development of therapeutic strategies against key proteins. Administration of a BET inhibitor and BET-PROTAC reduced the expression of these identified genes and displayed a significant antiproliferative effect on these cell models. In conclusion, we describe novel splicing genes amplified in luminal breast tumors that are associated with detrimental prognosis and can be modulated pharmacologically. It opens the door for further studies confirming the effect of these genes in patients treated with BET inhibitors. Abstract Alternative splicing is an essential biological process, which increases the diversity and complexity of the human transcriptome. In our study, 304 splicing pathway-related genes were evaluated in tumors from breast cancer patients (TCGA dataset). A high number of alterations were detected, including mutations and copy number alterations (CNAs), although mutations were less frequently present compared with CNAs. In the four molecular subtypes, 14 common splice genes showed high level amplification in >5% of patients. Certain genes were only amplified in specific breast cancer subtypes. Most altered genes in each molecular subtype clustered to a few chromosomal regions. In the Luminal subtype, amplifications of LSM1, CLNS1A, and ILF2 showed a strong significant association with prognosis. An even more robust association with OS and RFS was observed when expression of these three genes was combined. Inhibition of LSM1, CLNS1A, and ILF2, using siRNA in MCF7 and T47D cells, showed a decrease in cell proliferation. The mRNA expression of these genes was reduced by treatment with BET inhibitors, a family of epigenetic modulators. We map the presence of splicing-related genes in breast cancer, describing three novel genes, LSM1, CLNS1A, and ILF2, that have an oncogenic role and can be modulated with BET inhibitors.


It DESCRIBES A METHOD FOR PRODUCING CEMENT, THROUGH THE WARMING OF POWDER CRUDE in a preheater CYCLONE, calcining the raw powder PREHEATED, BAKING POWDER CRUDE calcined a baking oven ROTATING cooled cement clinker FORMED IN THE OVEN ROTATING BAKING AND GRINDING OF CEMENT cLINKER. The process is characterized in that a part FUELS HIGH QUALITY USED FOR THE PRODUCTION OF CEMENT, is replaced by low-quality fuels, AMENDING THE low-quality fuels are gasified in a fluidised bed, AND GAS IS DIVIDED INTO THREE pARTIAL FLOWS OF WHICH THE FIRST IS dRIVEN TO ROTATING BAKING OVENS, THE SECOND TO EXHAUST GAS OVEN COOKING GIRATORIO, and the third to the calciner.


MASON, JENNIFER E. Optimal Timing of Statin Initiation for Patients with Type 2 Diabetes. (Under the direction of Dr. Brian Denton). HMG Co-A reductase inhibitors (statins) are an important part of the treatment plan for patients with type 2 diabetes. However, the optimal time to initiate treatment is influenced by many factors. We investigate two such factors in this thesis: (1) the decision maker's criteria for optimal treatment initiation and (2) the patient's long-term adherence to treatment. Statins are effective in reducing cholesterol, a primary risk factor for cardiovascular disease in patients with diabetes. However, patients who are prescribed statins often stop taking the drug altogether or take less than the prescribed amount. This imperfect adherence can lessen the drug's benefit. We propose a Markov decision process (MDP) model to optimize the treatment decision for hypercholesterolemia in patients with type 2 diabetes while considering issues of adherence to statins. Our model incorporates a discrete time Markov process for adherence states of the patients. We found that in the long run approximately 25% of patients remain highly adherent, taking 80 to 100% of their medication. We also found, based on the optimization model, that patients with imperfect adherence should start statins 5 to 7 years later than their perfectly adherent counterparts. Although adherence levels greatly affect the optimal start time for statins, we found that starting statins later in life did not significantly increase the expected quality adjusted life years for patients with imperfect adherence. We conclude that it is more important for patients to improve their adherence than to adjust the timing of initiation to help compensate for imperfect adherence. We also consider three different decision making criteria with our model: society, patient, and third-party payer. Decision makers with these different perspectives have different objectives in mind. We have assumed that the patient is concerned with his or her quality of life, the third-party payer is concerned with minimizing expected costs, and society is concerned with maximizing expected rewards minus costs. These decision maker objectives are reflected in different reward functions in our MDP model. We find that it is optimal for patients to initiate statins early in the decision horizon under the patient perspective while the earliest optimal start times under the society and third-party payer perspectives are generally 4 and 15 years later, respectively. Finally, we formulate an inverse optimization model to estimate the implied societal willingness to pay. We use our MDP model and U.S. guidelines for initiating statins to estimate the implied reward for a year of quality life. Our estimates indicate a societal willingness to pay between $120,000 and $160,000 per quality adjusted life year. Optimal Timing of Statin Initiation for Patients with Type 2 Diabetes by Jennifer E. Mason A thesis submitted to the Graduate Faculty of North Carolina State University in partial fulfillment of the requirements for the Degree of Master of Science


tend a rookery, or join the fungus-eaters-nay, you may grow auriculas and carnations in a box even in the back street of a town, and their silent dainty ways and lovely faces will make you forget to write that sharp letter you intended for your medical brother. You will go instead to read a chapter of the adventures of Uncle Toby and Corporal Trim, of their gentle souls and of their hobby-horse, and so grow into peace with all men. My lear friends, my very dear colleagues with whom I have marched for nearly a quarter of a century, my less dear but most welcome younger friends, with whom I join hands first to-day, I have wandered with you for this hour, bestowing upon you much that is trivial, and forgetting much that it would have been better for you to hear. These occasions are scarcely fit for scientific lectures, which are not human enough for hours when we meet to welcome and fortify each other for the days that must come-days laden with many trials, laden with many hardships, laden with many griefs. You and I will need for our future work all the cheer and all the strength we can give each other. Our work lies day by day, in the darker chambers of human life. The wife or father will see the loved eyes grow silent, the loved cheek grow cold, in spite of all our skill, and we must too often close the door on a bereaved home with sinking heart. Yes, gentlemen, you may get, and I hope you will get, a certain use in these things; but you are not men if your hearts do not feel them. And so you may forget that after all there is more gladness than pain on the earth, more beauty of life springing from her bosom than death falling back to her. As you are young, you will rejoice in the life, you will have vision for life only; as you grow older you will be touched rather with the mystery of evildas Etend des IJcbns-with a sense of the weary and unintelligible weight which darkens the lot of so many beings made for happiness. The waning face is pressed close to the ruddy and bright cheekthe yearning mother cleaving to the child whose looks are so strangely far away; you will thrill within you as you see joy and anguish, life and death together, and fears will begin to cry in you, asking loudly, Have 1, by any deed of mine, by any want of forbearance of mine, by any heedless neglect, or by any lack of my help or sympathy, have 1, added to the sorrows or lessened the joys of the least of these? I do not wish for you the surly heart which will not hear these voices; if you hear them without remorse, God will indeed have given you his blessing.


8 Solcia E, Capella C, Sessa F, et al. Gastric carcinoids and related endocrine growths. Digestion 1986; 35: suppl 1: 3-22. 9 Borch K, Renvall H, Liedberg G, Andersson BN. Relations between circulating gastrin and endocrine cell proliferation in the atrophic gastric fundic mucosa. Scand J Gastroenterol 1986; 21: 357-63. 10 Poynter D, Pick CR, Harcourt RA, et al. Association of long lasting unsurmountable histamine H,-blockade and gastric carcinoid tumours in the rat. Gut 1985; 26: 1284-95. 11 Streett CS, Cimprich RE, Robertson JL. Pathologic findings in the stomachs of rats treated with the H-receptor antagonist tiotidine. ScantdJ Gastroeniterol 1984; 19: suppl 101: 109-17. 12 Carlsson E, Larsson H, Mattsson H, et al. Pharmacology and toxicology of omeprazole with special reference to the effects on the gastric mucosa. Scand J Gastroenterol 1986; suppl 118: 31-8. 13 Betton GR, Salmon GK. Pathology of the forestomach in rats treated for 1 year with a new histamine H,-receptor antagonist, SK&F 93479 trihydrochloride. Scand J Gastroenterol 1984; 19: suppl 10 1: 103-8. 14 Schafer LW, Larson DE, Melton LJ, et al. Risk of development of gastric carcinoma in patients with pernicious anemia: a population-based study in Rochester, Minnesota. Mayo Clin Proc 1985; 60: 444-8. 15 Svensden JH, Dahl C, Svendsen B, Christiansen PM. Gastric cancer risk in achlorhydric patients. Scand J Gastroenterol 1986; 21: 16-20. 16 Colin-Jones DG, Langman MJ, Lawson DH, Vessey MP. Postmarketing surveillance of the safety of cimetidine: 12 months mortality report. Br MedJ 1983; 286: 1713-6.


Two tests of divergent thinking ability, and three tests of convergent thinking ability were administered to 354 eighth graders, categorized as to race (black vs white) and socioeconomic status (high vs low). Consistent with previous studies, and with Rohwer's (1971) theory, neither ethnic nor social-class differences were obtained for the divergent thinking tests; both ethnicity and social class constituted significant sources of variance for the convergent thinking measures, with white and high-status youngsters performing significantly better than black and low-status youngsters on all three convergent thinking measures.


Soil nutrients are the necessary nutrients which the soil provides for plants growth.Some research showed that the soil nutriment has high spatial variability which affected by natural and human factors such as soil parent materials,regional climate,terrain,cropping system,fertilization and so on.The characteristic of soil spatial variability can be found not only in the regional scale but also in the field scale.In recent years,for aiming at minimizing fertilization and optimizing management of precision agricultural,many methods which improved continuously from fisher statistics to geostatistics,and then the new methods of neural network,geographical information technology and high accuracy surface model have been applied on measuring the spatial variability and distribution of the soil nutrients in different scales.Taking the geostatisics applied on the research on the spatial variability of soil nutrients as the starting point,the status of geostatistics-based research on the spatial variability of soil nutriments has been reviewed,which include using geostatistics to determine the reasonable soil sampling scheme,quantitative study and scale effect of the spatial variability of soil nutrients.On this basis,the recent research progress of methods and technologies of soil nutrients spatial variability were briefly described,which includes neural network technology,3S technology and high accuracy surface model.At the last,it comparatively analyzed shortages of all methods in researching the spatial variability of soil nutrients.Geostatistics method is concerned with detecting,estimating and mapping the spatial variability of soil nutrients,however it usually with intensive subjectivity and based on to much assumed conditions,moreover,the smoothing effect was existed in Kriging interpolation.The neural network technology and high accuracy surface model can improved the accuracy of interpolation and eliminate the smoothing effect,but the parameters of neural network can not be determined easily and the data operand and computer memory capacitance of high accuracy surface model are extremely heavy.The prediction of soil nutrients spatial variability by using geographical information technology has some uncertainty.At the same time some research directions of spatial variability of soil nutrients in the future are discussed.More scientific efforts should be focused on research in the spatial variability of soil nutrients in the different periods of crop growth,evolution mechanism of soil in four dimensional spaces and the uncertainty of environmental information.


Abstract
It had been investigated the swelling dynamics of monodomain mai!1 chain liquid crystal elastomers (MCLCE) in anisotropic solvent, liquid crystal molecule 4-cyano-4-n-pentylbiphenyl (5CB). Two condition samples groups were prepared to investigate irifluencing of volume and cross linking concentration on swelling dynamics of MCLCE. The first sample group was prepared in three different volumes and the second group was prepared in three types of different cross linking concentration. We obtained that the time constant of swelling dynamics depend on the si::e and cross linking concentration of MCLCE. We Observed that increasing volume of MCLCE and cross linker concentration resulted short time constant. We also obtained an anomaly data in 6 % cross linker concentration of MCLCE which tends to critical concentration of MCLCE.


Something about the idea of acting from duty seems cold and uncaring. When taking on a moral point of view, such as forcing ourselves to act from duty, we must divorce ourselves from our subjective feelings and our emotions. In this sense, taking a moral point of view alienates people from themselves, others, and their moral theory. In " Alienation, Consequentialism, and the Demands of Morality, " Peter Railton discusses these problems in the context of conventional morality and uses them to expose significant shortcomings in both consequentialism and Kantian morality. Similarly, in " Passions: An Oblique Offering, " Jacques Derrida attacks the concept of acting from duty and points out an underlying 'secret' behind language and human interaction. In this paper, I will show that Derrida's secret is precisely what Kantianism and consequentialism fail to acknowledge in their ethical formulas. To further my argument, I will discuss the moral implications in the context of drug use and relate my discussion to Derrida's " The Rhetoric of Drugs. " From this analysis, I will show that Derrida's concept of the secret flushes out deficiencies in consequentialism and Kantian morality that tend to alienate people from their emotions and prevent them from forming fulfilling relationships with others. To begin exploring the alienating problems with conventional morality, we should first look at Peter Railton's account of them. According to Railton: " Living up to the demands of morality may bring with it alienation – from one's personal commitments, from one's feelings or


The article presents the example of application of a Zaliznyak morphological dictionary to increase the quality of recognizing the handwritten texts. The results of the carried out work are given.


In this study, an attempt was made to develop oral sustained delivery formulations based on ionotropic gelation of sodium alginate using calcium chloride as the cross-linking agent. Tramadol hydrochloride was either incorporated into preformed calcium alginate gel beads (Method-1) or simultaneously incorporated during the gelation of sodium alginate by calcium chloride (Method-II). The beads prepared by the method I resulted in higher drug loading when compared to those prepared by the method II. The morphology of the beads was studied by means of scanning electron microscopy (SEM) and the physical state of the drug in formulations was characterized using X-ray powder diffraction analysis (X-RD) and differential scanning calorimetry (DSC). The results indicated that the drug was present in an amorphous state in the case of beads prepared by method I. The drug - polymer interactions were evaluated using FTIR and no interaction between the drug and polymer was observed. The in-vitro drug release was studied using USP XXIII (type II) dissolution test apparatus with distilled water as the medium. Further, the release data was analyzed to understand the mechanism of drug release and it was found to follow diffusion model. From this present study, it can be concluded that tramadol hydrochloride loaded calcium alginate beads prepared by ionotropic gelation method with calcium chloride as the cross-linking agent can be utilized for the development of a sustained release drug delivery system for tramadol hydrochloride. Corresponding author Tel +919666499784


Increasing integration of renewable energy resources emphasizes the importance of the grid-forming virtual synchronous generator (VSG)-based converters. An important issue in the control structure of these converters is the fault ride-through (FRT) capability under fault operating condition. In this paper a model predictive-based FRT control strategy is proposed to limit the converter current while ensures high power quality during fault situation. The proposed control method provides a fast dynamic response, high power quality, improved performance, and a simpler control structure. The effective performance of the proposed control method, as well as its superior performance in comparison with the conventional PI-based control and a model predictive-based control method, are validated through simulation results in MATLAB/Simulink.


Several commercially-available biological control agents were applied in a replicated single tree trial in Upper Lake, Lake County, California. Treatments included the biological control agents Pseudomonas fluorescens A506, sold as Bight Ban A506 ® (Nufarm Americas, Burr Ridge, Illinois), Bloomtime Biological ® FD Biopesticide "Strain E325" (Northwest Agricultural Projects, Pasco, Washington), biological yeast BCY-B, sold as Blossom Protect ® (Westbridge, Vista, California), and (new in 2012) the plant extract of giant knot-weed Reynoutia sachalinensis, sold as Regalia ® (Marrone Bio Innovations, Inc., Davis, California). Biologicals were compared to the grower standard tank mix of the antibiotics streptomycin and terramycin, and to the copper hydroxide plus copper oxychloride product, Badge X2 (Isagro-USA, Morrisville, North Carolina). Treatments were applied variously from April 14 to May 8 from 10% to "rattail" bloom. Fire blight infection potential reached treatable levels on April 19 and continued through June, well beyond the final treatment date. There were very few blight strikes (average 0.4 per week or 2.0 cumulative across treatments). Differences among treatments were insignificant, though there was a trend (p=.10). However, untreated controls harbored the lowest average weekly count (p=.4). thus block differences and treatment x block interactions (each p=.001) likely overwhelmed any treatment effects. Only A506 applied weekly at half rate resulted in greater than 5% of the fruit with noticeable russet (rating >7) perhaps due to diminished viability under warm conditions in late April and early May. BlossomProtect ® at 20-30% bloom had the least russet while the 80-90% bloom and full season applications had some russet. There were no significant differences in frost damage.


The extension of the MSC language with more advanced data concepts is one of the current topics of discussion in the MSC standardization community. We discuss some problems and possibilities. By means of two case studies we study the practical consequences of our proposed approach.


In this paper we consider the slightly L2-supercritical gKdV equations ∂tu+(uxx+u|u|p−1)x=0, with the nonlinearity 5<p<5+ε and 0<ε≪1. In the previous work of the author, we know that there exists a stable self-similar blow-up dynamics for slightly L2-supercritical gKdV equations. Such solutions can be viewed as solutions with a single blow-up point. In this paper we will prove the existence of solutions with multiple blow-up points, and give a description of the formation of the singularity near the blow-up time.


[1] On the basis that oxygen triple-isotope fractionation resulting from water vapor diffusion in air should differ in magnitude from that associated with equilibrium evaporation and condensation, and with very low sensitivity to temperature, Angert et al. [2004] postulated that the regression line of ln(1 + dO) versus ln(1 + dO) for meteoric waters may be displaced by very small, positive shifts from the corresponding data points for oceanic waters. In turn, the magnitude of this 'O-excess' in meteoric waters should be controlled primarily by the relative humidity of the vapor source region. Barkan and Luz [2007] discussed this concept further and defined the magnitude of the offset as:


We give the first systematic investigation of the design space of worm defense system strategies. We accomplish this by providing a taxonomy of defense strategies by abstracting away implementation-dependent and approach-specific details and concentrating on the fundamental properties of each defense category. Our taxonomy and analysis reveals the key parameters for each strategy that determine its effectiveness. We provide a theoretical foundation for understanding how these parameters interact, as well as simulation-based analysis of how these strategies compare as worm defense systems. Finally, we offer recommendations based upon our taxonomy and analysis on which worm defense strategies are most likely to succeed. In particular, we show that a hybrid approach combining Proactive Protection and Reactive Antibody Defense is the most promising approach and can be effective even against the fastest worms such as hitlist worms. Thus, we are the first to demonstrate with theoretic and empirical models which defense strategies will work against the fastest worms such as hitlist worms.


and A risk-based approach to evaluating northeast US fish community vulnerability to climate change. 71: 2323–2342. Risk assessment methods are used worldwide to evaluate threats posed by fisheries and other impacts on living marine resources, and to prioritize management of these threats. We derive a simplified risk analysis for aggregate fish communities as a preliminary tool to identify priorities for further detailed assessment. Because some of the largest observed rates of sea surface temperature increase are on the northeast US continental shelf, we focused on climate change-driven risks to marine communities in this region. We evaluated climate vulnerability for six communities across two ecosystems: both commercial and non-commercial demersal fish, pelagic fish, and benthic invertebrates in the Gulf of Maine (GOM) and Mid-Atlantic bight (MAB). Wefirstevaluatedthe probability thatanticipated climate changes(e.g. warming water,decreased salinity, increased acidity, altered boundary currents) would occur in these regions, and rated the potential severity of change over the next10 years. Then, we evaluated the sensitivity of each biological community in each region using 12 attributes (e.g. habitat and prey specificity, temperature and acidity sensitivity, larval dispersal, adult mobility, population productivity, etc.). Exposure to the key climate risks was related to community sensitivity in each region for an overall assessment of climate vulnerability. Climate risks from increased surface water temperature, sea level rise, and earlierspringwereratedmoderatetohighinbothregions,withadditionalmoderatetohighrisksintheGOMfromincreasedbottomtemperature,stratification,andriverinputs.Benthicinvertebrateswereratedmostsensitive,withdemersalsintermediateandpelagicslowest.TwoMABcom-munitieswereratedmoresensitivethancorrespondingGOMcommunities,butgreatershort-termclimaterisksintheGOMindicatedincreased exposure for GOM communities. Overall, this simple analysis may help prioritize short-term regional climate risk management action, thus addressing key conditions related to fishery fluctuations beyond fishing itself.


In given article the question on prevalence of neoplastic diseases among decorative animals and birds is considered. According to authors a skin new growth occupy a leading place among other kinds oncology.


This paper presents the results of a study developing expert system to support stress recognition based on Artificial Neural Network (ANN). Developed ANN is trained using data from Physionet database and collected data from other researchers. The implemented system for stress recognition uses drivers ECG signal, Galvanic Skin Response and Respiration Rate as parameters. Developed neural network was validated with 77 samples. Samples are obtained from subjects using Pasco sensors in 7D cinemas. Out of 77 samples, in 71% of subjects higher level of stress is recognized, while 29% of subjects are classified as subjects with normal vital functions. An accuracy of 99% and specificity of 98% is obtained.


The spatial distribution of resting spores of Synchytrium endobioticum was studied in three extents in two fields. The extents were sampled with a device that removed blocks of soil. Two extents were divided into three sections, 6 m apart, and one extent retained as a single block. The extents were divided into grains that measured either 20 cm 2 x 5 cm or 5 cm 2 x 5 cm, and the spore population of each grain estimated. The data were mapped, and subjected to analysis using Lloyd's Index of Patchiness. There were differing levels of spore aggregation across the grains. No particular pattern of aggregation emerged; the aggregates assumed random patterns of distribution. Biological, edaphic, and cultural dispersal mechanisms were considered, and it was concluded that the pattern of distribution likely followed gall production (biological dispersal).


Objective To investigate the breathing pattern of ribcage and abdomen on rest breathing in patients with moderate and severe chronic obstructive pulmonary disease(COPD).Methods 23 COPD patients subdivided into 13 in severe group(SG) and 10 in moderate group(MG),and 11 health persons as control group(CG),received pulmonary function tests and respiratory inductive plethysmography(RIP).Results Compared to CG,the breathing pattern in MG has no significant differences,however,Ti,Ti/Ttot,TPTEF/TE were significant different in SG,TPTEF/TE has an independent regressional relationship with FEV_(1.0)/FVC、FEV_(1.0)%.Conclusion The breathing pattern of ribcage and abdomen on rest breathing,especially TPTEF/TE,can evaluate the airflow limitation of severe COPD.


Red rust often occurs in mulberry plants in Guangxi and its regularity of outbreak was comparatively defi-nite,while mulberry rust was first observed in Guangxi.The present paper described the symptoms,pathogens,distribution and spreading of mulberry red rust and mulberry rust in Guangxi.A few control measures for the disease management have been suggested which include selection of resistant varieties,rational planting density,extirpation and burning of affected buds and leaves,unified pruning and timely spray of fungicides.


[Abstract] Hepatocellular carcinoma (HCC), as a global malignant tumor with high morbidity and mortality, has seriously endangered human health. In the treatment of HCC, chemotherapy resistance is the knotty problem. Long non-coding RNA (lncRNA), as a new multifunctional molecule with complex mechanisms, plays a role in the biological processes of HCC, such as development, progression, invasion and migration, and participates in the complex mechanism of drug resistance through abnormal regulation of gene expression. In this paper, to seek for the new method for solving the chemotherapeutic resistance of HCC based on the research of lncRNA, the effect and mechanism of lncRNA on chemotherapeutic resistance of HCC were summarized.


Abstract Drawing from a social constructionist perspective to written scholarly communication, this paper argues that training in academic writing for students in higher education especially in second language contexts should go beyond emphasis on grammatical correctness and paragraphing strategies, and also focus on the rhetorical character of academic discourse together with the mastery of its communicative protocols. Using the University of Ghana as a reference point, the paper reviews a selection of Ghanaian graduate students' awareness of the protocols that govern academic discourses in scholarly writing, and in consideration of their unique educational and socio-cultural circumstances, the paper proposes strategies, from the pedagogical and institutional standpoints, aimed at increasing students' awareness of the relevant communicative practices that engender credibility and accountability.


Abstract An 8- to 13-μm spectrum of comet Mueller 1993a, a dynamically new comet, was acquired when the comet was at R = 2 AU. Strong, structured silicate emission is present, closely resembling that seen in Comet P/Halley at smaller R. For the first time in a new comet, the 11.2-μm peak of crystalline olivine was detected, demonstrating that crystalline olivine particles were widespread in the solar nebula. Crystalline olivine particles could have formed in the inner protosolar nebula at temperatures greater than 1200 K; extensive radial mixing would have been required to transport these grains to the region of comet formation. Either there was more radial mixing in the solar nebula than some current theories predict or the olivine grains have a presolar origin.


Polypores are a group of diverse macrofungi that belong to phylum Basidiomycota (Basidiomycetes). The ability of polypores to produce enzymes has attracted the attention of scientists. These enzymes are increasingly being used for many industrial purposes, e.g. textile, pulp and paper, food, detergents and animal feeds. However, their expensive of production is the main hindrance to their use. Fortunately, most polypores can decompose cellulose, hemicellulose, and lignin in the plant cell walls. Solid state fermentation is a good method to degrade lignocellulose and to produce enzymes at low cost since residual agro-industrial waste can be used as the substrate for microorganism growth. Every day large amounts of residues and waste materials are lodged into the environment by industry, agriculture, and other ways leading to environmental problems. The present paper explores the isolation of polypore fungi and their production of lignocellulolytic enzymes, taking full advantage of various agro-industrial wastes as substrate.


Production wastes and residues generated in particular in the chemical and pulp & paper industries are currently incinerated or recycled. A stricter environmental legislation and the general prohibition imposed on waste incineration in some countries suggest to open new ways of waste disposal and resource recovery. This work describes how residual and waste materials can not only be disposed of but also converted into a raw gas which can be further processed to obtain valuable materials and synthesis gas in strict compliance with environmental standards by using various modifications of an entrained-flow gasification technology.


Purine receptors, G.Burnstock purification and reconstitution of the A1 adenosine receptor, J.Linden and R.Munshi monoclonal auto-anti-idiotypic antibodies to andenosine receptors, H.H.Ku et al modualtion of 3HDPCPX binding to membrane bound and solubilized A1 andenosine receptors by guanine nucleotides, K.N.Klotz et al molecular probes for andenosine receptors, J.W.Daly and K.A.Jacobson allosteric enhancers of andenosine A1 receptor binding and function, R.F.Burns and J.H.Fergus andenosine receptor ligands as therapeutic entities - molecular specificity in relation to functional and therapeutic activity, M.Williams et al characterization of the adenosine receptor that mediates inhibition of transmitter release at the frog neuromuscular junction, J.A.Ribeiro and A.M.Sebastiao function and structure of presynaptic andenosine receptors in peripheral adrenergic and cholinergic neurons, D.M.Paton magnesium-dependency of presynaptic inhibition by andenosine, T.W.Stone and J.T.Bartrup sensitivity to Mg++ of ligand binding to A1 adenosine receptors in ray brain and adipocytes, M.Reddington et al regulatory properties of andenosine A1 receptors in the CNS and peripheral tissues, D.M.F.Cooper and C.L.Boyajian pertussis toxin-sensitive G proteins and adenosine receptors in the central nervous system, J.W.Phillis mechanisms of inhibition of transmitter release by adenosine receptor activation, B.B.Fredholm et al on the transducing mechanism operated by the adenosine receptor mediating inhibition of transmitter release at the neuromuscular junction, A.M.Sebastiao calcium-dependent acetylcholine secretion - influence of adenosine, E.M.Silinsky et al inhibition of neuronal calcium currents by adenosine - role of G-proteins, R.H.Scott and A.C.Dolphin functional correlates of synaptic and extrasynaptic adenosine receptors in the hippocampus, P.Schubert and R.Mager exogenous and endogenous adenosine actions in the hippocampus, H.L.Haas and R.W.Greene potassium currents coupled to an A1 receptor by a G-protein in cultured central neurons, L.O.Trussell and M.B.Jackson.


COMPARISON OF CAUDAL BLOCK AND DEEP PENILE NERVE BLOCK FOR POSTOPERATIVE PAIN RELIEF IN PAEDIATRIC DAY-CASE CIRCUMCISION. 1, 2 1 1 3 ADAMU SA , PANDA US , SAMBO YT , SANI A . treat pain in the paediatric patients. Adudu et 1 al, reported a lagging behind trend in intraoperative pain relief for paediatric surgical patients. They found that the use of old modalities of pain relief with opioid drugs was up to 87.9% in their study while caudal block was only 7.1%. Day-case analgesia needs to be devoid of sedation, nausea and vomiting and this can be achieved by nerve blocks and neuroaxial blocks like caudal block which are safer but unfortunately are not often used in


The utility model relates to a tail pipe hanger running tool assembly in tail pipe well completion, mainly including a running rod (5), a running rod joint (6), a pressure block (8), a wheel ball bearing fixed seat ring (10), a slip back-off wheel (13), a key shaft (14), a back-off joint (15), a double public short-circuit (16), an upper main body of sleeve pipe packer (17), a rotary joint (24), a lower main body of sleeve pipe packer (26). The running rod (5) and the running rod joint (6), the running rod joint (6) and the key shaft (14) are connected by a T-shaped button. The slip back-off wheel (13) is connected with the back-off joint (15) by a T-shaped button. The double public short-circuit is connected with the back-off shaft (15) and the upper main body of the sleeve pipe packer (17) by screw thread. The rotary joint (24) is connected with the upper main body of the sleeve pipe packer (17) and the upper main body of the sleeve pipe packer (26) by a T-shaped button. The running tool could pressurize the packer directly through the pressure block and facilitate the base sealing of the packer.


PURPOSE: Glycogen synthase kinase (GSK) 3beta is an emerging and attractive therapeutic target against glioblastoma (GBM). Here, we investigated the efficacy of existing approved drugs inhibiting GSK3beta activity in vitro and in vivo on the basis of drug repositioning. METHOD: The effects of GSK3beta inhibiting drugs, cimetidine, lithium carbonate, olanzapine, and valproic acid, on the invasive ability of glioma cells (U87, T98G, U251) were evaluated using migration and invasion assays. GSK3beta activity after adding GSK3b inhibiting drugs was evaluated by detecting phosphorylation of glycogen synthase (GS) that is the primary substrate for GSK3beta. Expression and activity of matrix metalloproteinase (MMP)-2 were examined with gelatin zymography. These drugs were administered orally to GBM mouse model at therapeutic doses once daily for 2 weeks. Tissue sections were stained by standard hematoxylin and eosin technique, and satellite lesions that did not connect tumor bulk were counted. Immunohistochemistry was performed to detect the phosphorylated GS and nestin. RESULTS: Inhibition of GSK3beta activity by each drug was confirmed in GBM cells in vitro and GBM mouse model. Each drug attenuated GBM cell migration and invasion in dose-dependent manner. Combination of all 4 drugs remarkably decreased MMP-2 expression and activity. All drugs reduced satellite lesions and nestin-positive cells in vivo. No adverse effect was observed in mice. CONCLUSION: GSK3beta-targeted therapy for GBM patients with approved 4 drugs showed promising effect to attenuate glioma invasion, possibly via suppression of stemness.


This paper presents a comparative study of the performance of distance relays for transmission line high voltage (HV) 400 kV in Eastern Algerian transmission networks at Group Sonelgaz compensated by two different series Flexible AC Transmission System (FACTS) i.e. GTO Controlled Series Capacitor (GCSC) and Thyristor Controlled Series Capacitor (TCSC) connected at midpoint of an electrical transmission line. The facts are used for controlling transmission voltage, power flow, reactive power, and damping of power system oscillations in high power transfer levels. This paper studies the effects of GCSC and TCSC insertion on the total impedance of a transmission line protected by MHO distance relay .The modified setting zone protection in capacitive and inductive boost mode for three forward zones (Z1, Z2 and Z3) and reverse zone (Z4) have been investigated in order to prevent circuit breaker nuisance tripping to improve the performances of distance relay protection. The simulation results are performed in MATLAB software.


OBJECTIVE The aim of this study was to evaluate the effects of gradual discontinuation of benzhexol on cognitive function in schizophrenia.METHODS 60 schizophrenic patients who had received a second-generation antipsychotic(SGA) with concomitant for at least 3months were assigned to reseach group(n=30) and control group(n=30).Study Group phased out benzhexol within 4 weeks,while control group remained unchanged.Before and 1month after discontinuation of benzhexol,were administered.Clinical evaluation also included the Positive and Negative Syndrome Scale(PANSS),Wisconsin card sorting test(WCST),Continuous performance test(CPT),Wechsle memory scale(WMS).RESULTS Benzhexol was discontinued safely in patients of reseach group,and no emergent extrapyramidal symptoms were observed.study group improved significantly in cognitive funcition.CONCLUSION Discontinuation of long-term benzhexol use may be warranted in patients with schizophrenia treated with SGAs,as it may improve cognitive function without significant adverse effects.


OBJECTIVE:
To identify if a difference exists between the frequencies of cerebrovascular accidents (CVAs) in the first 24 hours after a National Basketball Association (NBA) championship finals game (CFG) as compared to days, in which no CFG was played.
 BACKGROUND:
Competitiveness without physical exertion has been shown to increase cardiovascular demand. A previous study showed a higher risk of myocardial infarctions (MIs) during Federation Internationale de Football Association (FIFA) games in a hosting nation; whereas, nations not hosting these games show no increase in MIs. Only one study analyzed CVAs during FIFA games and showed no increased risk of CVAs. Here, we investigate if a difference exists between the incidence of CVAs in the 24 hours after a NBA CFG and no CFG.
 DESIGN/METHODS:
We performed a retrospective cohort study of patients admitted to Jackson Memorial Hospital, Miami, FL, for CVAs during the NBA CFGs, in which the Miami HeatTM participated consecutively from 2011 to 2014. Patients from 5/31/2011-6/12/2011, 6/12/2012-6/21/2012, 6/6/2013-6/20/2013, and 6/5/2014-6/15/2014 were sorted according to CVA admission within 24 hours after an actual CFG start (Game group) or hypothetical game start during a no game day (No Game group). CVAs were further subdivided into ischemic and hemorrhagic. These primary and secondary endpoints were analyzed by ANOVAs.
 RESULTS: Of the 122 patients admitted for CVA during the CFGs, the Game group had 56 patients (mean age= 60.45) and the No Game group had 66 patients (mean age=64.27). ANOVAs showed no difference between Game and No Game groups with respect to the frequency of total CVAs (p=0.84), ischemic CVAs (p=0.71), or hemorrhagic CVAs (p=0.36).
 CONCLUSIONS: No significant difference in CVA frequency was appreciated during the NBA CFGs. This may be attributed to patients who are at risk for CVAs are older than the general NBA audience. Disclosure: Dr. Weiss has nothing to disclose. Dr. Grubb has nothing to disclose. Dr. Shah has nothing to disclose.


The emergence of 5th generation (5G) wireless technology has triggered the need for low-cost, compact, highperformance, and multi-band antennas, especially for flexible and wearable applications. This paper is an effort in this direction, and presents a compact and flexible antenna which operates at 5.3 GHz, 5.6 GHz, and 5.8 GHz. These bands fall in sub-6 GHz band allocated by the Federal Communications Commission (FCC) for potential 5G applications. The flexible antenna is designed on 0.1 mm thick Polyethylene Terephthalate (PET) substrate with loss tangent of 0.002 and relative dielectric constant (Er) of 3. The antenna geometry consists of symmetrical slots based bus-shaped patch which is excited by microstrip line inset feed having an impedance of 50 O. The overall profile of the antenna is 44mm×70mm×0.1mm(LxWxH). Simulations using ANSYS High Frequency Structure Simulator (HFSS) show that the antenna has S11 values of −18.5 dB at 5.3 GHz, −26.76 dB at 5.6 GHz, and −12.79 dB at 5.8 GHz. It has a Voltage Wave Standing Ratio (VSWR) of 1.27 at 5.3 GHz, 1.096 at 5.6 GHz, and 1.59 at 5.8 GHz. The antenna demonstrates gain of 7.8 dB at 5.3 GHz, 5.9 dB at 5.6 GHz, and 4.39 dB at 5.8 GHz. The proposed antenna exhibits a very good radiation efficiency of 86.5%.


The prime assets of an oil and gas company are its reserves and resources; they are the most important information about a company, and are the basis on which capital is raised to carry out its activities. A reporting issuer is a company that sells securities on the open market, but not necessarily on an exchange. Canadian National Instrument 51-101 (NI 51-101) governs the disclosure that is required of a reporting issuer. It has been in force since September 2003 and mandates the disclosure of Proved and Probable reserves and allows the disclosure of other categories of resources by reporting issuers. This paper provides a background to the securities regulation and regulatory reporting regime of NI 51-101, including recent amendments. It is not a substitute for the expert advice that should be sought by anyone attempting to fulfill securities regulatory requirements. Some trends and issues on oil and gas reserves and resource estimation and disclosure in Canada and the international arena are also discussed.


Both PN and NP InP solar cells on Si wafers were made with AM0 one-sun efficiencies up to 11%. Cells were irradiated to an equivalent fluence of 4/spl times/10/sup 18/ 1 MeV electrons/cm/sup 2/ with alpha particles from an Am-241 source, losing only /spl sim/25% of their BOL output power. Although the BOL efficiency is about half that of GaAs/Ge cells, InP/Si cells have power outputs exceeding typical GaAs/Ge cells at very high fluences, and are intended for use in high radiation orbits where EOL power of GaAs/Ge cells is inadequate. SIMS data shows zinc diffusion from an InGaAs contact cap controls junction depth in PN InP/Si cells, while an epitaxial emitter layer controls the junction depth in NP cells. NP cells have much lower emitter sheet resistance, but require a tunnel junction near the InP/Si interface because of Si diffusing out from the wafer, doping the initial InP n-type.


This dissertation is focused on interaction patterns in interpersonal conflict within organizations. Starting point is the interpersonal theory (IPT; Kiesler, 1983; Leary, 1957) that distinghuishes two dimensions to describe interpersonal (conflict) behavior, namely dominance-submissiveness and friendliness-hostility. Furthermore, with respect to interaction patterns, which exist when two people influence each other's consecutive behaviors, IPT poses that dominance pulls submissiveness and vice versa (complementary interaction pattern), whereas friendliness leads to friendliness and hostility to hostility (symmetrical interaction pattern). Former research revealed insufficient evidence for complementary dominance-submissiveness, but amply sufficient evidence for symmetrical friendliness-hostility. Moreover, conflict behavior in organizations has never before been described and predicted with IPT. Therefore, the first goal of this dissertation was to test hypotheses about interaction patterns in interpersonal conflict within organizations. The second goal of this dissertation was to examine whether the micro phenomenon of conflict interaction is influenced by the macro phenomenon of organizational structure. Organizations can roughly be divided into bureaucratic systems, characterized by low decision participation and by relatively simple, standardized work, versus organic systems, characterized by high decision participation and by relatively complex work that is coordinated by means of mutual adjustment. Former research revealed communication differences between bureaucratic, non-participative systems and organic, participative systems. In organic systems, the communication climate is more open than in bureaucratic systems. Therefore, conflict handling is expected to be more open, assertive, and confrontative than in bureaucratic systems. However, ther are only a few studies of differences between bureaucratic and organic systems with respect to interaction patterns in interpersonal conflict. Another organization variable that probably influences conflict interaction is status difference. In accordance with findings from former research, it might be expected that high-status persons will show more dominant and more hostile conflict behavior than low-status persons. However, no specific predictions can be derived from former research about the influence of status difference upon interaction patterns in interpersonal conflict. The third goal of this dissertation was to gain insight into determinants of effective conflict management. On the basis of earlier research it can be stated that more dominant and more hostile conflict behavior is less effective. Once again, no direct indications can be derived from former research about the effectiveness of interaction patterns in interpersonal conflict.


During the report period we completed several studies and embarked on a new set of laboratory experiments. We also hired a new post-doctoral Research Associate, Momir Stepanovic, who has gradually assumed leadership in the laboratory work. The other person involved has been graduate student Brian Eichelberger, who will complete his Ph.D. based on this work by late spring of this year. We have also continued to collaborate with our previous postdoctoral Research Associate, Valery Le Page, through a consulting arrangement. In the following sections we summarize work that has been completed and either in print, in press, or in final stages of preparation for publication; current work being carried out in the laboratory; and plans for the coming year. Work completed in 2002: 1. Modeling the physical and chemical states of PAHs in the diffuse interstellar medium. 2. Hydrogenation and charge states of polycyclic aromatic hydrocarbons in diffuse clouds. 3. Laboratory studies of chemical reactions involving carbon chain anions.


The present invention provides novel sirtuin-modulating compounds and methods using the same. Sirtuin-modulating compounds may increase cell longevity and, for example, aging or stress related diseases or disorders, diabetes, obesity, neurodegenerative diseases, cardiovascular diseases, blood coagulation disorders, inflammation, cancer, and / or It can be used in the treatment and / or prevention of a wide variety of diseases and disorders, including flushing and diseases or disorders that would benefit from increased mitochondrial activity. Further provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.


It is pointed out that plasma turbulence may play a more major role during solar flares than acknowledged previously. One theoretical and two new observational (from YOHKOH) arguments are presented to support this view.


PROBLEM TO BE SOLVED: To provide a nonaqueous electrolyte solution capable of more improving cell characteristics of a lithium ion secondary cell and to provide a lithium ion secondary cell having excellent cell characteristics using such a nonaqueous electrolyte solution. SOLUTION: A nonaqueous electrolyte solution used for a lithium ion secondary cell further contains a compound of silicon fluoride such as 1,2-bis-(dimethylfluorosilyl)ethane together with a lithium salt having an oxalato complex as anion, or these two components and carbonate ester having halogen atoms. COPYRIGHT: (C)2011,JPO&INPIT