Introduction Most cardiac surgery patients, with or without diabetes, develop perioperative hyperglycaemia, for which intravenous insulin is the only therapeutic option. This is labour-intensive and carries a risk of hypoglycaemia. We hypothesised that preoperative administration of the glucagon-like peptide-1 receptor agonist liraglutide reduces the number of patients requiring insulin for glycaemic control during cardiac surgery. Methods In this randomised, blinded, placebo-controlled, parallel-group, balanced (1:1), multicentre randomised, superiority trial, adult patients undergoing cardiac surgery in four Dutch tertiary hospitals were randomised to receive 0·6 mg subcutaneous liraglutide on the evening before surgery and 1·2 mg after induction of anaesthesia or matching placebo. Blood glucose was measured hourly and controlled using an insulin-bolus-algorithm. The primary outcome was insulin administration for blood glucose above 8·0 mmol/L in the operating theatre. Research pharmacists used centralised, stratified, variable-block, randomisation software. Patients, care providers, and study personnel were blinded to treatment allocation. Results Between June 2017 and August 2018, 278 patients were randomised to liraglutide (139) or placebo (139). All patients receiving at least one study drug injection were included in the intention-to-treat analyses (129 in the liraglutide group, 132 in the placebo group). In the liraglutide group 55 (43%) patients required additional insulin compared to 80 (61%) patients in the placebo group, absolute difference: 18% (95% CI 5·9–30·0, p = 0·003). Dose and number of insulin injections and mean blood glucose were all significantly lower in the liraglutide group, see figure. We observed no difference in the incidence of hypoglycaemia, nausea and vomiting, mortality, or postoperative complications. Discussion Preoperative liraglutide, compared to placebo, reduces insulin requirements while improving peri-operative glycaemic control during cardiac surgery.


This paper presents an AM receiver implemented in a flexible a-IGZO TFT technology. The circuit consists of a four-stage cascode amplifier at the RF input, a detector based on a source follower, and a common-source circuit for the baseband amplification. The measured conversion gain is very flat against frequency and exceeds 15 dB for carrier frequencies ranging from 2 to 20 MHz, which covers a relevant portion of the shortwave radio band. The 3 dB-bandwidth of the baseband signal ranges from 400 Hz to 10 kHz: this is comparable to the so-called voice band and is suitable to low-rate data communications. Additionally, the AM receiver is tested in combination with two textile antennas. The flexible a-IGZO receiver successfully detected the baseband signal through the textile antennas, demonstrating for the first time wireless transmission for this class of technologies.


In order to investigate immunological activity of radix dichroa extractive and febrifugine,proliferation of mouse spleen T lymphocyte and B lymphocyte was determined by MTT assay in vitro.The results showed that proliferation of mouse spleen lymphocytes were significantly inhibited by radix dichroa extractive when its concentration was up to 200mg/L(P0.05);ConA-induced T lymphocyte proliferation was significantly promoted by radix dichroa extractive at 10mg/L concentration(P0.05);LPS-induced B lymphocyte proliferation was also prometed when its concentration ranged from 10mg/L to 200mg/L(P0.05).Proliferation of mouse spleen lymphocyte was significantly inhibited by febrifugine when its concentration reached 0.1mg/L(P0.05);ConA-induced T lymphocyte proliferation was prometed when its concentration ranged from 0.001mg/L to 0.01mg/L(P0.05)and were significantly prometed at 0.000 1mg/L concentration(P0.05);LPS-induced B lymphocyte proliferation was prometed by febrifugine when its concentration ranged from 0.000 1mg/L to 0.005mg/L(P0.05).The results suggested that radix dichroa extractive and febrifugine have better immune-enhancing activity.


An experiment was carried out to investigate the morphological response of mechanically stimulated myoblasts that were cultured on a collagen-coated silicone ribbon and were subjected to tension for 6 hours. Images of the cells were taken by a CCD camera and input into a computer every 10 minutes for 8 hours. Both morphological change represented by a shape index (SI) and cumulative migration of the cells were measured every hour. An increase of the SI and decrease of the migration velocity were observed during tensile loading. Considering the cell structure, it is considered that hydrodynamic force of the cytosol would act on cytoskeletons due to the deformation of the cell. The fluid-structure interaction analysis was carried out to estimate the stress of the filament, where the actin filament and cytosol were modeled as an elastic cylinder and viscous fluid, respectively. The results of the calculation suggested that the rounding of the cell might not be caused by the break of the filament due to the hydrodynamic force.


It is well known that cosmic ray (CR) fluxes which are observed near the Earth are subject to the influence of solar activity (SA). Usually, the sunspot number Rz is used as an indicator of such influence. The high correlation exists between long-term sets of data on cosmic ray fluxes and Rz: the correlation coefficient r 0.85. However, the physical mechanism of CR modulation includes the scattering of charged cosmic ray particles on magnetic irregularities of interplanetary magnetic field (IMF) which solar wind carries out from the Sun to space. Now there are long-term sets of data on CR fluxes and parameters of interplanetary space responsible for cosmic ray modulation. Here we consider the relationship of CR fluxes measured in the atmosphere in our balloon experiments with strength B of IMF. If the relation of CR fluxes and IMF strength is found one can evaluate the unmodulated CR flux in the interstellar medium taking B = 0. This unmodulated CR flux could be compared with the flux of CRs observed by spacecraft Voyager-1 at the distance d 115 a.u.


Status of the agricultural land use under the Polissya, Zhytomyr region conditions has been analyzed. Common approaches to the efficient land resources use have been characterized. Global trends in organic production development have been investigated. The facilities of growing the organic produce in Polissya have been considered. Suggestions toward the sustainable land use implementation in the context of globalization have been developed


FIELD: manufacturing processes in machine engineering, working large planar surfaces. SUBSTANCE: method comprises steps of imparting blank cross and longitudinal feed motions and imparting rotation to tool. In order to enlarge manufacturing possibilities, to enhance working efficiency due to combining finish and rough working processes, to improve roughness of worked surface and to increase useful life period of needle milling cutters, to simplify their mounting-dismounting along periphery of drive disc in diametrically opposite places, at least four needle milling cutter with individual drives are used. Speed of longitudinal motion feed of blank is determined according to given formula depending upon diameter of needle milling cutter, their number and revolution number of drive disc. EFFECT: enlarged manufacturing possibilities, enhanced efficiency of method, improved roughness of worked surface, increased useful life period of needle milling cutters, their simplified mounting-dismounting operations. 2 dwg


This article focuses on one aspect of the European Community's ("EC's") proposed Investment Services Directive ("ISD"): the potential impact of the ISD on the automation of the European securities markets.' The ISD will not only create a single European market for investment services, but will also play a part in determining how the European markets will operate, who will be permitted to participate in them, and how technology will affect their operation. Monitoring technology developments is particularly relevant as computers are rapidly making traditional methods of trading securities and of clearing and settling transactions obsolete. Once the ISD comes into effect, it will reduce the regulatory burden on a national of any member state of the European Community that establishes an investment business and provides investment services throughout the Community. The ISD will give an investment firm access to membership in the stock exchanges and other organized securities markets located throughout the EC. Thus, an investment firm domiciled in one member state ("home state") may set up a branch or subsidiary in another state ("host state"), and will have the right to become a member of a stock exchange in the host state. Alternatively, the investment firm may acquire an existing member firm in the host state.2


The Baltic States are of geopolitical interest to Ukraine in the development of Baltic-Black Sea cooperation and in the pursuit of their own political and economic goals. Ukraine is constantly improving its foreign economic relations with Latvia, Lithuania and Estonia. Latvian-Ukrainian economic cooperation has good potential for development. Today, there are all prerequisites for the further development of bilateral economic cooperation, especially given Ukraine's progress towards EU integration. The global Covid-19 pandemic has significantly affected trade relations between Ukraine and these countries, so it is important to assess the negative effect of the pandemic on the balance of goods and services, as well as the dynamics and volume of foreign direct investment between selected countries. Table 1 presents data on trade relations between Ukraine and the Baltic States for January-September 2019–2020. It should be noted that in 2020, due to the pandemic, the volume of Ukrainian exports decreased compared to the same period in 2019. Ukrainian exports to Latvia and Estonia decreased by almost 30%, but to Estonia by less than 1% Imports also suffered from the current situation, however, if imports from Latvia and Lithuania to Ukraine decreased by 10.7% and 26.9% respectively, Estonia, on the contrary, exported goods to Ukraine in 2020 by 34% more than in 2019. Ukraine shows a positive trade balance with Latvia, as Ukrainian exports exceed Latvian imports to Ukraine. Ukraine's trade relations with Lithuania have always recorded a negative balance. The Ukrainian balance of goods


A simulation method to estimate counting efficiencies for 222 Rn and 220 Rn collected in a scintillation flask has been studied. The concept of this Monte Carlo calculation was based on a relationship between a residual range of an alpha particle colliding with a scintillator and an output-pulse-height distribution. The relationships were investigated using collimated beams of 241 Am because the pulse-height distributions differed not only with residual ranges but with distances between the collision point and the window of the flask. Using the distributions, counting probabilities for various alpha energies were estimated. The simulation for the counting efficiency was carried out using the following procedure: (1) a radiating point is determined by two random functions; (2) a radiating direction of an alpha particle is determined by other two random functions; (3) a counting probability for the alpha particle is calculated by the pulse-height distributions determined by the residual range at the collision point; and (4) the calculating cycle from (1) to (3) is repeated 100,000 times. The method was verified against experimental values for a standard 222 Rn gas and then adapted to 220 Rn. This method is very useful and effective because counting efficiencies of various scintillation flasks for various alpha particles can be estimated.


Photo‐numeric scales could lack precision and objectivity on evaluating the improvements on wrinkles after a treatment with botulinum toxin type A. The authors suggest a new digital evaluation method to analyze its effectiveness.


There is the design of isolation and detection of influenza
viruses ODN in this study. Usage of conjugated MPs and
QDs-based hybridization target molecule and their application
for the detection of the avian influenza virus (H5N1) is
presented. For analysis of oligonucleotide labelled with Cd QDs
two electrochemical methods were applied. For cadmium (Cd peak)
differential pulse voltammetry was used, for oligonucleotide
(CA peak) square wave voltammetry (SWV) was applied.


This review mainly evaluates the conception of impaired fasting glucose about its necessity and rationality,significance,current status,distribution and the relationship with the definition of impaired glucose tolerance;investigate its significance and its relations with other diseases or risk factors and then analysis the interference method to impaired fasting glucose such as lifestyle and drugs.


The study of species-area relationships in protected natural areas (PNAs) is an effective tool for designing nature reserves and managing biological diversity. Ten North Central Texas PNAs were studied to understand how plant species richness is related to PNA size. The species-area model was applied to total plant species, native plant species, selected native speciose plant families and invasive plant species. Results indicate that area is a significant predictor of species richness (r2 = 0.60) for both total species and native species in North Central Texas PNAs. Habitat diversity as measured by topographic relief and topographic abruptness is also shown to be a significant predictor of plant species richness in North Central Texas PNAs. Introduced species richness could not be predicted from area alone but was explained by perimeter and perimeter/area ratio and one proxy measure of habitat diversity. The estimates of z values range from 0.15 to 0.30, while c ranges from 0.60 to 1.42 for species-area relationships, both of which fall within the range of values estimated by previous research. Such estimates allowed us to evaluate effective management schemes for North Central Texas PNAs plant diversity. The results of this research permit us to examine the invasion of exotic flora in Texas PNAs and to predict how such invasions will reduce native species richness if conservation management practices are not implemented.


Abstract A common approach for lower emission of NOx from diesel engines is to use exhaust gas recirculation (EGR) coolers where part of the exhaust gas is returned to the cylinder to reduce the combustion temperature. Nonetheless, the deposition of various species, i.e. soot particles, on surfaces deteriorates the thermal efficiency of EGR coolers. This study investigated the impact of surface treatment on particulate fouling of a rectangular EGR cooler. An experimental setup was assembled through which the uncoated and coated plates were exposed to the flow of exhaust flue gases. The cooler surfaces were coated by ceramic-based materials with resistance to high temperatures by spraying. The results showed that surface modification abated soot deposition to some extent and the deposit layer was easily flaked off with a force of 0.8 N when it was scratched with a nano-intender. Contrariwise, the deposit formed on the uncoated surface did not result in similar propensity and instead it required a larger force of 2.25 N. This implies weaker stickiness of soot deposit on the investigated coatings compared to baseline stainless steel surface. It was also found that the electron donor component of surface energy would determine the tendency of a surface to foul or not.


. The hydrodynamic calculations of nonlinear self-excited radial pulsations were done for the models of W Vir stars with mass 0.6 M 0 and luminosities from 794L© to 3981L 0 . The periods of the models are longer than 10 days. The pulsations are shown to be accompanied by periodic shocks that change the density distribution in the pulsating stellar atmosphere. At radii less than 5 R ph , where R"h is the radius of the photosphere, the mean dynamic scale height is nearly five times the static scale height. In this region of the atmosphere the mean radii of outer mass zones do not change perceptably. On the other hand, at radii larger than 5 R ph the scale height is of the order of R P h so that the outermost layers ultimately expand with a velocity exceeding the local escape velocity. The mass flux in the atmosphere increases with decreasing mass to radius ratio and mass loss ratein W Vir type variables is in the range from 2 X 10" 6 M e -yr 1 to 10 5 M e -yr 1 .


This study titled Organizational Performance Public Service / Government of Yogyakarta. This study aims to understand / know the Organizational Performance Public Service / Government. This research was conducted in a one-stop service office of Yogyakarta and data collection is done by using observation and interview. Performance Public Service Organization is closely associated with penyelenggaraaan good governance (good governance) and for anyone who is dealing with the bureaucracy. The importance of looking at performance organization Public Service because the bureaucracy is still fine tune the public not as a customer in the delivery of services, but rather as an object of services that can be treated arbitrarily, bureaucratic apparatus does not understand people's needs and technological progress even tend to be responsive, innovative and apathetic in organizing public services. Key words : Performance, Public Organizations


: Image scrambling methods are necessary for original image processes in applications of quantum image processing like quantum image encryption, which increases the strength of the encryption process, and the resulting image is di ffi cult to identify and detect its details. As well as obtain a high entropy value and a histogram with a uniform peak for the encrypted image. Most researches focus on scrambling the position only or the value only; however, the quantum image scrambling researches focused on scrambling both position and value together is few. The idea of the study is developing a genetic algorithm to generate di ff erent schemes of scrambling based on the fast and elementary schemes with changing the quantum logical gate (NOT / C-Not) to get the best scheme that meets the requirements such as the cost, the complexity or the type of the image. One of the essential benefits of the proposed work is developing a general framework for the automatic generation of a suitable scrambling scheme based on image type, method, and logical circuit. The tests are simulated using MATLAB. The result confirms that hybrid value / position schemes with a C-Not gate have an entropy value close to 8 and a flat histogram. It is implicated that this framework will benefit many researchers in selecting the most appropriate scrambling method for their works.


This chapter discusses that the curious fact that a concept of hierarchical ranking or seniority has been prominent in most of the more than thousand years of the history of the Russian state. The extraordinary prolificity of the house of Rurik in subsequent centuries aggravated the inherent defects of the original system of succession in more than one way. The most common treaties between Russian princes in the Middle Ages were those which established or reaffirmed seniority of one of the signatories, by recognizing his status as elder brother. The operation of mestnichestvo is known in considerable detail, on account of the relative abundance of the surviving materials. The Table of Ranks was one of the best prepared legislative innovations of the Petrine era. The practice in a number of West European countries had been studied.Keywords: house of Rurik; mestnichestvo; Russian state; Table of Ranks


The mental health and wellbeing of university students has become a more prominent issue in recent decades. Various factors contribute to student mental health challenges, such as developmental transitions, belonging to equity groups, and specific fields of study. As universities prioritise student mental health and wellbeing, there is a need for resources and training to enhance the ability of professional and academic staff to provide appropriate support. To build staff capacity and confidence in recognising and responding to students experiencing psychological distress, a regional Australian university developed a health and wellbeing toolkit. The toolkit provides information and resources on various topics, including identifying warning signs, managing mental health conditions, responding to disclosures of harassment or assault, and implementing inclusive learning environments. The toolkit will continue to evolve based on staff and student feedback and usage. It is fostering a shared understanding of the role all staff can play in supporting student mental health and wellbeing, as part of a broader university strategy to maintain mentally healthy campuses. By providing a comprehensive yet easy to use resource, the toolkit is a significant advancement in the University's efforts to equip all staff to support the mental health and wellbeing of students.


The formation of the deep northern Valles Marineris troughs is conjectural [e.g., 1]. We report on a dyke swarm exposed on the floor of Ophir Chasma, one of the northern Valles Marineris troughs. Dyke thickness is commonly tens of meters, similar to dykes exposed in continental shields on Earth, and suggest erosion of kilometers of rocks above them. Glacial erosion is the most likely erosional process.


The study of decision-making is an intellectual discipline; mathematics, sociology, psychology, economics, political science, artificial intelligence, neuroscience and physics. Conventional decision theory tells us what choice of behavior should be made if we follow certain axioms. Scientific curiosity instructs us to reconsider beyond any area in which we have defined ourselves. We design the intertwining of brain, genetics, phylogenetics, and artificial and neural networks in financial trading to find the best combinations of parameter values in financial trading, incorporating them into ANN models for stock selection and trader identification. The purpose and goal of the paper is to make financial decisions in the intertwining of the brain, genetics, phylogenetics and artificial neural networks, focusing on opening new foundations, giving insights into the foundation rock that lies beneath that soil. Science seeks basic natural laws. Mathematics seeks new theorems to build on old ones. Engineering builds systems to address human needs. The three disciplines are interdependent, but different and yet Claude Shannon simultaneously makes a central contribution to all three disciplines, this was the guiding idea of our work (finance, neuroscience, artificial intelligence).


Double-shelled NiFe PBAs nanocages with abundant CN vacancies have been fabricated through an ion-exchange reaction based on a nanoscale Kirkendall effect followed by mild thermal activation, which have an impressive OER activity with low overpotential and long-term stability.


In March 2021 the Tri-Agency released its Research Data Management Policy, including its three pillar requirements. This article reviews some key points from the Alliance RDM (Portage Network) workshop "Putting the Tri-Agency Policy into Practice: Workshopping Your Institutional Research Data Management Strategy."


Heavy metal pollution is a worldwide problem. This study was conducted in a turquoise mine in Nyshabour (Iran) to find accumulator plant(s). Concentrations of metals were determined both in the soil and the plants growing in the mine. Concentrations of total K, Ca, Na, Mg, Mn, Zn, Fe and Cu in the mine area were higher than the control soil. The results showed that four dominant vegetations namely Vincetoxicum scandens Sommier et Levier., Stachys lavandulifolia Vahl., Phlomis anisodonta Boiss. and Onosma bulbotrichum Dc.prod accumulated heavy metals. Based on the results, it was concluded that Stachys lavandulifolia Vahl. is the best accumulator for Fe , but the best Cu accumulator is Onosma bulbotrichum Dc.prod.


The present invention provides foams for continuously supplying foams for coating or filling a foaming agent within a molten metal to be able to prepare a continuous foam metal, an apparatus for preparing foams, and a method and an apparatus for preparing a foam metal using the foams. The foams for continuously supplying a foaming agent to a molten metal, comprises: a strip or rod-shaped base material which is made substantially of the same metal as the molten metal to form a foam metal, and foams which are filled in a filling portion formed in a longitudinal direction of the base material. The present invention can prepare a high quality foam metal by supplying foams while a base material is molten through supply of foaming agent to molten metal.


The invention relates to the use of fragments and heparin fractions activity Antithrombin, which is less than 50 U / MG for the preparation of a medicament that inhibits the reproduction of human immunodeficiency virus HIV.


MicroRNA (miR)-628-5p serves as an antitumor gene in a variety of cancers; however, the role of miR-628-5p in colorectal cancer remains largely unclear. The purpose of this study was to investigate the role and mechanism of miR-628-5p in colorectal cancer. Reverse transcription-quantitative PCR (RT-qPCR), colony formation assays and flow cytometric analysis were used to determine the expression levels of miR-628-5p in colorectal cancer tissues and cell lines, and the proliferative ability of colorectal cancer cells. TargetScan version 7.2 and dual-luciferase reporter assay were performed to predict and confirm miR-628-5p target genes. The expression levels of cyclin D1 (CCND1) and related genes were determined using RT-qPCR or/and western blotting analysis. miR-628-5p mimics and CCND1 plasmids were used to overexpress miR-628-5p and CCND1; it was demonstrated that the expression levels of miR-628-5p were significantly downregulated in colorectal cancer tissues and cell lines. miR-628-5p mimic-transfected cells inhibited the proliferation and induced apoptosis of HT-29 cells. CCND1, a downstream effector of miR-628-5p, promoted the proliferation and suppressed apoptosis of HT-29 cells, and the effects were reversed by miR-628-5p mimics. In conclusion, the present study suggested that colorectal cancer progression may be regulated through the miR-628-5p/CCND1 axis, and miR-628-5p could be used as a potential diagnostic and prognostic biomarker for colorectal cancer.


Due to various recent improvements in cellular technology, communication networks now offer information flows with a wide range of transmission speed and service quality characteristics. These characteristics are more highly noticeable in intelligent networks, particularly when IoT technology is used. Regulation and high-quality transmission of such massive volumes of data present severe issues among virtual operators engaged in the communications sector and utilizing cellular network infrastructure to provide video surveillance services for its consumers. Unfortunately, no single approach exists that enables the execution of high-quality incoming traffic flow maintenance and the allocation of information transmission resources in diverse networks. One of the methods to address these issues is mathematical modelling, which takes into consideration the unique characteristics of traffic flows that emerge and are approved for servicing. Our work addresses this problem by designing a resource allocation strategy for an isolated LTE network cell with heterogeneous traffic flows while sharing its radio resources. Traffic sources considered are operator surveillance system's video cameras that use cellular network infrastructure to deliver data to analytical centers. A mathematical model is used to study the process of sharing a resource, which takes into consideration the priority of real-time traffic, the elasticity property during file transfer, and the access restriction for all threads, based on the quantity of resource held by each thread. When sharing the resources of an isolated LTE network cell with heterogeneous traffic flows. Traffic sources are surveillance system operators' video cameras that use cellular network infrastructure to deliver data to analysis centers. Algorithms for evaluating the characteristics of the service of applications are constructed and the dependence of the characteristics on the restriction of access is investigated. Using the developed model, a scenario of dynamic distribution of the access node resource between incoming sessions has been developed, which allows creating conditions for differentiated servicing of heterogeneous traffic flows based on access restrictions and resource loading by each of the considered flows.


In applying principal components for reducing the dimension of the data before clustering, it has ordinarily been the practice to use components with the largest eigenvalues. We prove, by means of a mixture of two multivariate normal distributions, that this practice is not justified in general. A relationship between the distance of the two sub populations and any subset of principal components is derived, showing that the components with the larger eigenvalues do not necessarily contain more information (distance). This result is further demonstrated through hypothetical as well as real situations which use actual data. The effect of scaling the variables on the distribution of the information to different components is investigated. An application to a mixture of two normal distributions is illustrated by utilizing a set of generated data in which the information is concentrated in the components with the largest and the smallest eigenvalues.


MD Ibanez, PR del Rio, EM Lasa. Ann Allergy Asthma Immunol. 2018;121(2):235–244.e3

To determine the efficacy of available diagnostic tools in penicillin allergy relative to the results of drug provocation tests (DPTs). The tools used for comparison were clinical history, skin testing (skin prick and ID), and specific immunoglobulin E (sIgE) to penicillin and its determinants.

Included were 732 consecutive children ≤14 years of age who presented to 1 of multiple allergy departments and reported an adverse drug reaction to penicillin G, penicillin V, Amoxicillin Clavulanate, or Cloxacillin.

Twenty-three allergy centers participated. A uniform protocol was used at all centers and included a clinical history (after which the clinical researcher was asked, in their expert opinion if this as a clear-positive, doubtful, or clear-negative case of allergy), skin prick …


ABSTRACT High pressure native polyacrylamide gel electrophoresis has been designed to visualize the dissociation/association process of protein complexes. This paper reports this methodology in more quantitative way by inspecting pressure dissociation of pig heart lactate dehydrogenase, a tetrameric protein, which was extensively investigated in spectroscopic methods. We observed the change of electrophoresis pattern with pressure up to 150 MPa. By optimizing the buffer system and careful image analysis of the stained gels, we quantified all the dissociates in the process of pressurization. We discussed the characteristics of our methodology by comparing the result with the previously reported.


As politicians and pollsters are well aware, it is easy enough to get different answers to the same question by adjusting the details of the question posed. So I clarify at the outset that I am not considering depression in the broadest sense of any depression occurring in any older person. It seems self-evident that differences are present when defined this way; that is, this includes people with depression in dementia, post-stroke depression, depression in the context of other chronic illnesses and so any assessment of clinical or biological factors would yield differences (in cognition, physical symptoms, and so on) compared to a similar sample of depression in all younger adults. Rather I focus the question on unipolar major depressive disorder (MDD). This is because if there are no differences in late-life MDD compared with younger adults, then it seems unlikely that such differences are present in broader constructs of unipolar disorder (minor depression and dysthymia) and pragmatically because this more tightly defined group has been better assessed. A problem in addressing this question is that relatively few studies have directly compared aspects of depression in older and younger people. Thus, the answer will necessarily be limited and subject to a potential "absence of evidence" error. Here, three key areas of evidence where such comparisons have been made will be examined.


The $q$-Heun equation and its variants arise as degenerations of Ruijsenaars-van Diejen operators with one particle. We investigate local properties of these equations. In particular we characterize the variants of the $q$-Heun equation by using analysis of regular singularities. We also consider the quasi-exact solvability of the $q$-Heun equation and its variants. Namely we investigate finite-dimensional subspaces which are invariant under the action of the $q$-Heun operator or variants of the $q$-Heun operator.


Poster: "ECR 2015 / C-0463 / Correlation study between MR quantitative cardiac iron accumulated and left ventricular function in patients with β-thalassemia major" by: "P. Peng, Z. Ling, Y. Guangxin, L. Liling, H. Zhongkui; Nanning/CN"


Despite the economic importance of the muscoid flies as a group, very few quantitative data are available on the effect of temperature on the duration of the incubation period. Wardle ( 11 ) presented valuable data on the incubation period of eggs of Lucilia sericata Meig. at a series of constant temperatures. Notes on the incubation period of Stomoxys calcitrans L. by Melvin ( 5 ) and of Haematobia irritans L. by Melvin and Beck ( 6 ) are available.


Short and long fiber reinforced thermoplastics are a feasible alternative to develop lightweight materials for semi-structural and structural applications, respectively. These composites present a layered structure showing a complex tridimensional structure along the molding, created during the forming stage. The details of short fiber orientation in a center-gated disk with diameter of 1.38 mm were obtained in several regions including the gate and advancing front. Several modifications were introduced in the method of ellipses to obtain unambiguous orientation of 30 % short glass-fiber PBT. The unambiguous Arθ component was successfully obtained with the modified method. The results also showed an asymmetric distribution of fiber orientation that gradually washout as the flow progress. In addition, the initial orientation measured at the gate presented a fiber distribution different from the random orientation that is assumed in literature for a center-gated disk. Additionally, the initial results of this modified method to assess the complex structure of a 30 % long glass-fiber PP end-gated plaque are shown.


Fieldwork carried out in 2010 at the Iberian oppidum of La Bastida de les Alcusses has revealed the existence, under the floor of the main gate, of a layer with abundant wood-charcoal and metal objects. Both the typology of the objects and their stratigraphic-spatial layout suggest that this is a ritual deposition related to the foundation of the site. Among the timber remains two species have been identified (Aleppo pine and holm oak) and they might be interpreted as lumber pieces or wooden objects that were consciously burnt before being deposited, although we do not rule out the possibility that it was wood harvested specifically for this purpose.


Leptin is a protein hormone produced by adipocytes. It is secreted into the blood stream and plays a key role in regulating body energy homeostasis by inhibiting feeding behavior followed by weight loss. Because protein stability and bioefficacy are major problems in the biotechnology and biopharmaceutical industries, if leptin can be used for the therapeutic proteins, the stability and bioefficacy are needed to be improved. In this study, we mutanted the surface residues of leptin in a systematic way by displaying 3D structure of leptin on pymol program. We compared the biological activities of leptin and mutant leptin ex vivo using MCF7 breast cancer cell line and in vivo using a male C57Bl mouse model. Mutant leptin treated MCF7 cells displayed better cell proliferation than wild type leptin. The biological activities of leptin and mutant leptin were also tested in a semi‐quantitative STAT3 and ERK phosphorylation bioassay. A representative experiment showed at least 2‐fold higher activity in mutant leptin treated group. To assess the in vivo activity, each group of mice was treated with saline, leptin, and mutant leptin for 20 days and the differences in body weight, food intake, abdominal fat contents, and TG concentration were measured. Mutant leptin appeared to decrease the body weight and food intake in male C57Bl mice more significantly than wild type leptin. As a consequence of decreased body weight, the mutant leptin treated mouse group showed decreased abdominal fat contents and low triglyceride (TG) concentration. These results indicate that the mutant leptin is more effective than wild type leptin.


Today's digital world necessitates the adoption of encryption techniques to ensure secure peer-to-peer communication. The sole purpose of this paper is to conglomerate the fundamentals of Blockchain, AI (Artificial Intelligence) and DNA (Deoxyribonucleic Acid) encryption into one proposed scheme, KryptosChain, which is capable of providing a secure information exchange between a sender and his intended receiver. The scheme firstly suggests a DNA-based Huffman coding scheme, which alternatively allocates purines—Adenine (A) and Guanine (G), and pyrimidines—Thymine (T) and Cytosine (C) values, while following the complementary rule to higher and lower branches of the resultant Huffman tree. Inculcation of DNA concepts makes the Huffman coding scheme eight times stronger than the traditional counterpart based on binary—0 and 1 values. After the ciphertext is obtained, the proposed methodology next provides a Blockchain-inspired message exchange scheme that achieves all the principles of security and proves to be immune to common cryptographic attacks even without the deployment of any smart contract, or possessing any cryptocurrency or arriving at any consensus. Lastly, different classifiers were engaged to check the intrusion detection capability of KryptosChain on the NSL-KDD dataset and AI fundamentals. The detailed analysis of the proposed KryptosChain validates its capacity to fulfill its security goals and stands immune to cryptographic attacks. The intrusion possibility curbing concludes that the J84 classifier provides the highest accuracy of 95.84% among several others as discussed in the paper.


The purpose of this study is to describe the application of good corporate governance in optimizing service governance in the perum damri branch of the City of Surabaya. This research method uses a descriptive type of qualitative research with data collection techniques carried out through observation techniques, interviews, documentation, and previous research. The results showed that the Perum damri Branch of Surabaya City has not fully applied the principles of good corporate governance as a whole from the 5 principles of achieving goals, there is still 1 principle that is well implemented, namely the principle of independency. Transparency has not been carried out due to the absence of operational information services, accountability has not been fully implemented, there is still no guarantee of employee competence and the company governance system has not run optimally, responsibility has not been fully relaxed due to the absence of social impact programs for the community in the company environment,  fairness has not been fully implemented because the community complaint box facility is still not available and there are still many fleets for rejuvenation and fleets are carried out for people with disabilities.


We have systematically studied the structural and physical properties of the superconducting hydrated Lix(H2O)yTaS2 (0.22 ≤ x ≤ 0.58, y ≈ 0.86). The powder X-ray diffraction patterns suggest that all...


In this article we explore the possibility that if music theory, to acquire deeper insight into musical problems, has borrowed theoretical and methodological tools offered by linguistic science, then an approach in the contrary direction might be useful in elucidating linguistic problems, particularly those of prosody and poetic rhythm.


The magnetic order in the diluted magnetic semiconductor barrier of double AlAs/GaAs:Mn quantum well structures is investigated by Monte Carlo simulations. A confinement adapted RKKY mechanism is implemented for indirect exchange between Mn ions mediated by holes. It is shown that, depending on the barrier width and the hole concentration, a ferromagnetic or a spin-glass order can be established.


The present work numerically evaluates a Liquid Resin Infusion (LRI) process for different configurations of empty Y-shaped channels, inserted in a rectangular plate with porous medium. The LRI consists of the injection of a polymeric resin in a closed mold composed of


495 Background: B is a small molecule proteasome inhibitor that affects multiple signaling pathways. S is an orally active multikinase inhibitor with known activity in renal cell cancer. In vitro data has shown that S and B interact synergistically in a number of neoplastic cell lines to cause apoptosis. A phase 1 trial of S and B demonstrated no unexpected toxicities. We now report the results of this phase 2 efficacy trial. Methods: Eligibility included cytologically confirmed clear cell cancer with no prior chemotherapy, PS 0-1, Cr < 1.5 mg/dl, normal LFTs. Regimen: S 200 mg PO BID and B 1mg/m2 IV days 1,4,8, & 11 every 21 days. Patients were treated until disease progression or unacceptable toxicity. The primary objective of the study was to achieve a PFS of 70 weeks. Results: Seventeen patients were enrolled between April of 2011 and January of 2013. Median age was 62y (range 44-75). Four of 17 patients had known brain metastasis on entry to the trial. Median number of cycles = 4 (range 1-45+). Respo...


Large extrusion bending parts are the main frame par ts of aero craft and extrusion stretch- bending is an considerably important form ing process in aeronautics and astronautics industry. In recent years, the incre asing attention paid on the air pollution speeds up the process of vehicles ligh ting and spreads the use of the aluminium extrusions in automotive production. T his paper presents a summarization of the research works emphasizing close-sect ion extrusions stretch-bending forming from four aspects, i.e. material propert ies, cross section deformation, wrinkle and spring back. We propose the current basic research emphases and forecast the tendency of the stretch-bending formin g works.


The paper presents an analytical solution for the dispersion of a solute of two immiscible viscous fluids in the presence of an irreversible first-order chemical reaction. The effects of both homogeneous and heterogeneous reactions on the dispersion are studied. The results are presented graphically and in tabular form for various values of viscosity ratio and pressure gradients on the volumetric flow rate and effective Taylor dispersion coefficient. It is found that for homogeneous chemical reaction, the effective Taylor dispersion coefficient decreases as reaction rate parameter increases. The validity of the results obtained from an analytical method for two fluid models is verified by comparison with the available one fluid model results, and good agreement is found.


Peer-to-Peeroverlay networks have gained in popularity as they present an effective alternative to resource-sharing. Users' anon ymity though, has allowed peers to also share malicious artifacts that may be wro ngly perceived as popular resources. A number of proposed reputation schem es attempt to address this problem by recording the requestor's satisfac ion at the end of each operation. In such schemes, a node that has no evidence o n quality of a sought resource may consult with recommending peers befor e a download operation commences. Existing reputation mechanisms are p rone to attacks that exploit the formation of groups of colluding peers. The latter collectively attempt to either raise or lower one's reputation value. We p ropose aReputation Monitoring Mechanism (RMM) that restricts the extend of those attacks by continually monitoring the reputation level of each peer over a number of consecutive time periods or epochs. ShouldRMM observe rapid changes in the reputation value of a node, it smooths out these variatio ns; thus, it provides resistance to attacks by colluding peers. RMM actions depend on both peer reputation value and variations during several pochsin recent past.


The diet of the Cape clawless otter Aonyx capensis was investigated at the Dwessa Nature Re serve and Mkambati Nature Reserve on the Wild Coast, Eastern Cape Province, South Africa. Their diet was more varied at Mkambati (15 prey species) than Dwessa (7 species). In terms of percentage relative frequency of occurrence, the spiny lobster Panulirus homarus was found to be the most common prey item at both Mkambati (37.93%) and at Dwessa (35.21%), followed by fish (31.03% and 36.62%, respectively), crab (22.41% and 19.72%) and molluscs (3.11% and 4.23%). No significant differences were found in spraint dry masses between sites (15.10 g vs 17.95 g) or between masses of the diet categories for the two regions, but, when converted to 'fresh' mass, mean spraint mass was significantly lower at Mkambati than Dwessa (108.08 g and 135.73 g, respectively). When diet categories were compared using ANOVA, only fish were found to be significantly different when expressed as fresh mass. Spiny lobster mandibles collected from spraints were used to estimate otter prey size preferences by comparing with wild caught lobster dimensions (ANCOVA, paired t tests, correlation and regression). Otters ate spiny lobsters with carapace lengths between 39.5 and 72.0 mm CL. Differences in diet were compared with published data from elsewhere. Lobster and fish are relatively abundant within these reserves, suggesting prey availability rather than selective feeding influenced diet.


Uplift rate and rainfall intensity are the main factors controlling the development of experimental erosion landform. However, characteristics of sand mound to be eroded (mainly permeability) are also an important factor determining the way of experimental landform development. This time I would like to discuss the development of experimental landform with uplift and rainfall erosion from the view point of effects of permeability of sand mound, especially based on the results of runs with the same uplift rate (0.36mm/h), runs 26, 27, 32 and 38.


Free vibration analysis is carried out on axially inhomogeneous beams resting on Winkler-Pasternak elastic foundation. The material properties of the beam like Young's modulus, modulus of rigidity and material density are considered to be varying along the length direction following constant, linear and exponential material models. The beam is subjected to different combinations of clamped and simply supported boundary conditions. The formulation is based on Timoshenko beam theory and energy method along with Hamilton's principle is used to derive the governing equations. The effect of material gradation and the 2 parameters of elastic foundation on the natural frequencies are studied in detail. The present results are validated by comparing them with established ones and satisfactory matching is observed.
HIGHLIGHTS

Free vibration behavior of axially functionally graded beams in investigated
Three different material models and three boundary conditions are considered
Effect of two parameter elastic foundation is considered
Timoshenko beam theory and Rayleigh Ritz method are employed
It is found that the stiffness of elastic foundation significantly affects the natural frequency of the beam

GRAPHICAL ABSTRACT


Congestion control algorithm in Vehicular Networks (VANETs) has been extensively studied. However, most of congestion control algorithms are not directly applicable for event-driven safety messages. The event-driven safety messages have stringent requirement on delay and reliability. A single delayed or lost of event-driven safety messages could result in loss of life. In dense network, a large number of vehicles broadcast a beacon messages at a high number of frequencies, the Control Channel (CCH) will easily congested. It's very important to keep the CCH channel free from congestion. Hence, this study takes a closer look at existing congestion control algorithms to solve congestion problem because it affects the performance of event-driven safety messages. In this paper, we propose the congestion control algorithm for event-driven safety messages. The effectiveness of the proposed congestion control algorithm is evaluated through the simulations.


The passage of colloidal particles across the endothelial wall of sinusoids and their accumulation in the marrow parenchyma have been studied, after an intravenous injection of a large amount of India-ink and saccharated iron oxide.
The injected colloidal particles are first deposited evenly on and in the sinusoidal endothelium within 30 minutes, and then beginn to enter into the marrow parenchyma, passing through the endothelial wall. Thereafter, the colloidal particles are rapidly taken up by the reticular cells in the parenchyma and accumulate in their cell bodies. In these processes of transportation of colloidal particles, the phagocytic activity of both the sinusoidal endothelium and the reticular cells in the marrow parenchyma seem to play a major role.
The chemically stable carbon particles are gradually brought together into large masses formed by coalescence of carbon-laden reticular cells and persist for a long time; whereas the colloidal particles of saccharated iron dioxibe phagocytized by reticular cslls disappear rather rapidly within a month or two, probably having been utilized in the iron metablism of the organism.


The radical copolymerization with propagation and depropagation is presented in order to estimate reactivity rate of monomers and K_(11)(the equilibrium constant for propagation and depropagation) in the copolymerization of α-methylstyrene-co-methylmethacrylate and α-methylstyrene-acrylonitrile. The value of α-methylstyrene and methylmethacrylate and K_(11) are found to be 0.48, 0.47 and 5.0 respectively. The value of α-methylstyrene and acrylonitrile and the K_(11) are found to be 0.1251, 0.0577 and 23.8 respectively. The treatment rate constant of α-methylstyrene-co-methylmethacrylate and α-methylstyrene-co-acrylonitrile in the copolymerization is estimated to be 2.5, 80.72 regardless of monomer feed composition.


The purpose of this article is to evaluate the benefits of legal harmonization within the framework of international trade law, with a particular focus on development and the effects on developing countries. It will begin with theoretical and normative claims for and against harmonization, and then turn to the Agreement on Sanitary and Phytosanitary Standards and the Agreement on Technical Barriers to Trade in order to explore these claims within a specific context. Overall, we will see that harmonization is largely an ineffective tool for dealing with development issues. While it is important to develop institutional capacity in developing countries to deal with health, safety and technical standards, across-the-board harmonization fails to recognize the need for countries to adapt laws and legal institutions to domestic conditions. My exposition of the impact that the international trade regime can have on developing countries through a relatively circumscribed policy area, SPS and TBT measures, points to the need for anticipating similar impacts in other areas in which the international trade regime promotes legal harmonization. Copyright 2004, Oxford University Press.


Although agricultural biodiversity was not originally included as a thematic area in the Convention on Biological Diversity when it was first drafted in the early 1990's, it was soon recommended to be included by scientific advisors and biodiversity practioners alike, in view of the fact that agricultural biodiversity has tremendous relevance for linking conservation to economic development. Interestingly, the convention did not restrict itself to the more common and well-known aspects of agricultural biodiversity, such as crop genetic resource conservation, but made a special effort to include functional groups which provide essential ecosystem services, such as pollinators, soil biota and natural pest control agents (Costanza et al 1997, Daily 1997, Pimentel et al 1997).


Simple Summary The hypothesis of this experiment proposes that it could be possible to identify pregnant goats through maximum progesterone milk levels at any time in the pregnancy, and that there is an optimal moment to apply a lactation inhibitor to dry off lactating goats. The maximum progesterone concentration in milk varied depending on the season of the year, and those concentrations were similar for pregnant and non-pregnant goats, but significantly higher in the case of gestating goats with four foetuses, for which it would be possible to distinguish the pregnancy. The milk yield of goats at mating does not affect fertility until a value of at least 3250 mL/day. If using lactation inhibitors, their application up to the 10th week post-mating would be optimal for drying off lactating goats. Abstract Two of the most important problems in high-yielding dairy goat farms are early and accurate pregnancy diagnosis and the appropriate dry off of lactating does before the next kidding. The hypothesis posits that it could be possible to identify pregnant does through maximum progesterone milk levels at any time during the pregnancy, and that there is an optimal time to apply a lactation inhibitor to help dry off lactating does. Therefore, 114 Murciano-Granadina breed goats were used, from which 74 goats were inseminated at week 20 of lactation and samples of milk from pregnant and non-pregnant goats were taken at two-week intervals. The average maximum progesterone milk levels were higher outside the natural breeding season (40° latitude) than in the breeding season (11.6 ± 1.13 vs. 8.6 ± 1.02 ng/mL), although the levels from pregnant and non-pregnant goats were similar (10.85 ± 1.3 vs. 9.74 ± 1.6 ng/mL), except in the case of pregnancy with four foetuses (12.5 ± 1.3 ng/mL). Milk yield at mating does not affect fertility until a value of at least 3250 mL/day. Pregnancy started to affect milk yield up to the +7th week and was 59.9% lower in the +10th week after mating, so the use of lactation inhibitors could be more effective from this latter week. In conclusion, the results show that it is not possible to detect gestation in goats reliably through the maximum concentration of progesterone in milk at any time during lactation, except in the case of goats gestating four foetuses, that the milk yield of goats at mating does not affect fertility until a value of at least 3250 mL/day, and that from the 10th week post-mating, the application of lactation inhibitors would be optimal.


The study aims to describe the implementation of teaching writing by using picture strip story to improve the students' writing skill at MTs Ma'hadul Muta'alimin Katerban Ngawi. This research is a Classroom Action Research (CAR). The writer took the first grade students of MTs Ma'hadul Muta'alimin Katerban Ngawi as the subject of
study. To collect the data, the writer conducted observation, document and test. The writer conducted Classroom Action Research (CAR) in three cycles in which each cycles consisted of four elements: planning, implementing, observing and reflecting. The problem found in the third meeting is that the students did not concentrate on their writing because they were not interested in the picture strip story and some of them were not active to study English. The writer used new picture strip story to influence students' attention, so that they focused on the material. The result of the research shows that 13 students increased their writing achievement and 2 students had static achievement. The students felt happy and were more active and enjoyed studying English. The research result of pre-test is 66.25 and post-test is 82.81, which means that the students' writing skill increases after they were taught using picture strip story.


In a respected Monitorskopea public opinion poll in 1984, Italians were a s k e d t o i d e n t i f y t h e mo s t important development in the country's history of the past fifty years. Thirty-six percent of those polled chose terrorism, sixteen percent fascism, thirteen percent for the country's post-World War II reconstruction, and twelve percent for liberation in 1945. No other event reached double figures in the poll. For the previous fifteen years, Italy had suffered from the highest inc idence of terror i sm among the developed countries of the Western world. As a result, the Monitorskopea poll reflected the traumatized mood of the nation f o l l ow i n g a s p r e e o f t e r r o r


In this article, the conjugate gradient method with adjoint problem is applied for the identification of the heat and mass transfer coefficients at the surface of drying capillary-porous bodies. The unknown functions are supposed to vary in time and along the surface open to the surrounding environment. The inverse problem is solved by considering either the heat or the mass transfer coefficients as unknown, as well as by considering simultaneously both functions as unknown. The effects of temperature and moisture content measurements on the inverse analysis are examined. A comparison of different versions of the conjugate gradient method is also presented as applied to the inverse problem under study.


Compressible granular materials are involved in many applications, some of them being related to energetic porous media. Gas permeation effects are important during their compaction stage, as well as their eventual chemical decomposition. Also, many situations involve porous media separated from pure fluids through two-phase interfaces. It is thus important to develop theoretical and numerical formulations to deal with granular materials in the presence of both two-phase interfaces and gas permeation effects. Similar topic was addressed for fluid mixtures and interfaces with the Discrete Equations Method (DEM) [R. Abgrall and R. Saurel, "Discrete equations for physical and numerical compressible multiphase mixtures," J. Comput. Phys. 186(2), 361-396 (2003)] but it seemed impossible to extend this approach to granular media as intergranular stress [K. K. Kuo, V. Yang, and B. B. Moore, "Intragranular stress, particle-wall friction and speed of sound in granular propellant beds," J. Ballist. 4(1), 697-730 (1980)] and associated configuration energy [J. B. Bdzil, R. Menikoff, S. F. Son, A. K. Kapila, and D. S. Stewart, "Two-phase modeling of deflagration-to-detonation transition in granular materials: A critical examination of modeling issues," Phys. Fluids 11, 378 (1999)] were present with significant effects. An approach to deal with fluid-porous media interfaces was derived in Saurel et al. ["Modelling dynamic and irreversible powder compaction," J. Fluid Mech. 664, 348-396 (2010)] but its validity was restricted to weak velocity disequilibrium only. Thanks to a deeper analysis, the DEM is successfully extended to granular media modelling in the present paper. It results in an enhanced version of the Baer and Nunziato ["A two-phase mixture theory for the deflagration-to-detonation transition (DDT) in reactive granular materials," Int. J. Multiphase Flow 12(6), 861-889 (1986)] model as symmetry of the formulation is now preserved. Several computational examples are shown to validate and illustrate method's capabilities.


This paper presents the development of a dual frequency printed planar reflector working in Ka-band, including the definition of the antenna structure required for the considered application, the design of performing dual frequency reflecting cells and of a complete antenna based on these cells.


In this article, we treat the turning points of singularly-perturbed linear differential systems and reduce their parameter singularity's rank to its minimal integer value. Our approach is Moser-based, i.e. it is based on the reduction criterion introduced for singular linear differential systems by Moser [21]. Such algorithms have proved their utility in the symbolic resolution of the systems of linear functional equations [5, 6, 8], giving rise to the package ISOLDE [7], as well as in the perturbed algebraic eigenvalue problem [13]. In particular, we generalize the Moser-based algorithm described in [4]. Our algorithm, implemented in the computer algebra system Maple, paves the way for efficient symbolic resolution of singularly-perturbed linear differential systems as well as further applications of Moser-based reduction over bivariate (differential) fields [1].


It's well known that the spatial ±1 steganography on JPEG decompressed images is relatively easier to detect than those never compressed ones. Though some targeted methods that are special for JPEG decompressed carriers are designed, there are still some drawbacks among them. First, most methods are not perfect or even don't work for embedding rate as low as 0.0003 bits per pixel, or even lower. Second, few methods are able to estimate embedding rate for LSB matching. Finally, many methods require estimation of the JPEG quality factor, which makes the methods slow and not so robust for big JPEG quality factors. This paper revisited a color based method raised by Westfeld ten years ago, unearthed the reason why it's so reliable and also extended it to a practical non-parameter quantitative steganalyzer for JPEG decompressed carriers. Error rates of our new method was evaluated in this paper.


Multistate coherent system reliability analysis is a new problem of reliability theory. Its reliability logical models satisfy some coherent conditions,so this kind of systems are of some good properties , which are useful for system reliability analysis. Only the models satisfy the corresponding conditions ,can the multistate coherent system reliability analysis be developed conveniently.In this paper ,a method is studied on how to check the monotinicity and coherence of a given system.


Homodyne detection of scattered CO/sub 2/-laser light demonstrates a close relation between microturbulence level and energy confinement in the Wendelstein VII a stellarator during both Ohmic and neutral-beam heating experiments. With the onset of neutral injection an abrupt order of magnitude decrease in (deltan/n)/sup 2/ accompanied by a broadening of the fluctuation spectra is observed, indicating an almost immediate improvement of containment time.


Higher education has two basic uses,knowledge and education. The former means that higher education can help spread,create and be applied to practice by the courses such as teaching,study and professional training and so on. The latter means that the uses of higher education on morality and ethic. The two uses are important equally in the view of globalization. We mustn't emphasize the former and neglect the latter.


A simple, fast and accurate method is presented for the measurement of the power system frequency. The method is based upon counting the number of strips (or samples) between zero crossings during one complete cycle of the sinusoidal waveform. Since the number of strips is usually not an integer, an estimate is derived that is very close to the actual value. The frequency is directly calculated front the number of strips. The measurement can be performed in at most 25 ms for a 60-Hz frequency, and at most 30 ms for a 50-Hz frequency. If the sinusoidal signal is sampled at 8 kHz for the purpose of measurement, the proposed method achieves accuracy in measuring the frequency of about 0.0001-0.0004 Hz.


The invention relates to a method for conducting rapid genetic transformation of alfalfa. According to the method, alfalfa germinated seeds are directly transformed through an agrobacterium-mediated method, and no tissue culture process is needed. The method is characterized by including the following steps that the alfalfa germinated seeds are adopted to serve as transformation acceptors, and transformation is achieved through mediation of agrobacterium with exogenous genes and further including the specific steps that 1, sterile alfalfa mature seeds are germinated; 2, cultivation and injecting transformation are conducted on agrobacterium with foreign genes; 3, co-culturing and bacteria-elimination are conducted; 4, resistant plants are obtained; 5, transgenetic plants are obtained. The method is relatively simple in operation, and no expensive instrument and tool are needed; the germinated seeds are utilized to serve as the acceptors, limitation of the genotype is avoided, materials are obtained conveniently, and a strict tissue cultivation process is avoided; the transformation method is short in impregnation time, the transformation cycle is greatly shortened, and remarkable advantages are achieved compared with other alfalfa transformation methods mediated by the agrobacterium.


Santeria is a cultural religion that is a mixture of the Yoruba African religion and Catholicism. The formation of this religion was due to occurrence of The Atlantic Slave Trade and the stripping of beliefs of the enslaved people sometimes forcing them to convert to Catholicism. Over the years, Santeria has become one of the main religions in the Caribbean, where it is now most specifically practiced in Cuba. Santeria is a unique cultural religion in which there is worship of approximately 400 deities called Orishas. The worship of the Orishas are varied from each deity. The main focus of this research was to explore the various deities and the worship that many committed believers followed and continue to follow to this day. Mentor: Scooter Pegram, Department of Modern Languages and Department of Minority Studies, College of Arts and Sciences, Indiana University Northwest


Students learn through connections when understanding is enhanced by a more holistic view of the content. When mathematics is presented from diverse perspectives, students with diverse backgrounds, expectations, histories, and experiences benefit greatly. In this article the author addresses the need to teach mathematics with cultural competency that meets the needs of all diverse learners.


Slovakia's institutional system showed a sufficient degree of
stability. The country's economic development was stable too,
as GDP growth neared 6 percent, unemployment declined and the
annual inflation rate remained relatively low. The favorable
trend of foreign direct investments' inflow continued. Slovakia
successfully seized most opportunities ensuing from its
full-fledged EU membership. Although the center-right
administration of Mikulas Dzurinda did not control a majority
in parliament, it managed to put through most reform laws. The
government's determination to keep in the reform course could
not be shaken even by minor conflicts within the ruling
coalition. Opposition parties, for their part, did not manage
to railroad through parliament a constitutional bill seeking to
shorten the current electoral term and call early parliamentary
elections.


Summary: In the Netherlands the disintegration of processed strawberries, accompanied by unpleasant odour and flavour, is generally caused by the mould Byssochlamys nivea. Pectolytic enzymes produced during the growth of the mould are responsible for the disintegration. The organism is not killed by the heat treatment normally applied to strawberries.


With the intensifying challenges of global environmental change, sustainability, and biodiversity conservation, the monitoring of the world's remaining forests has become more important than ever. Today, Earth observation technologies, particularly remote sensing, are at the forefront of forest cover monitoring worldwide. Given the current conceptual understanding of what a forest is, canopy cover threshold values are used to map forest cover from remote sensing imagery and produce categorical data products such as forest/non-forest (F/NF) maps. However, multi-temporal categorical map products have important limitations because they inadequately represent the actual status of forest landscapes and the trajectories of forest cover changes as a result of the thresholding effect. Here, we examined the potential of using remotely sensed tree canopy cover (TCC) datasets, which are continuous data products, to complement F/NF maps for forest cover monitoring. We developed a conceptual analytical framework for forest cover monitoring using both types of data products and applied it to the forests of Southeast Asia. We conclude that TCC datasets and the statistics derived from them can be used to complement the information provided by categorical F/NF maps. TCC-based indicators (i.e. losses, gains, and net changes) can help in monitoring not only deforestation but also forest degradation and forest cover enhancement, all of which are highly relevant to the 2030 Agenda for Sustainable Development and other global forest cover monitoring-related initiatives. We recommend that future research should focus on the production, application, and evaluation of TCC datasets to advance the current understanding of how accurately these products can capture changes in forest landscapes across space and time.


We show how to use Schwinger's method to evaluate determinants of differential operators that appear quite often in ordinary quantum mechanics. Although this method was introduced by Schwinger in the early fifties to compute effective actions for quantum electrodynamics and was recently applied by him in the Casimir effect, it has never been used in nonrelativistic problems. As explicit examples we compute the partition functions for both the bosonic and the fermionic harmonic oscillator.


R ESEARCH performed over the past few years, in particular , has made it clear that, in addition to the liver, hepatocyte growth factor (HGF) 1 affects virtually every tissue in the body ranging from the nervous system to the immune and reticuloendothelial systems. Recent findings have also revealed that the biological responses of target cells to HGF are not confined to the induction of cell proliferation and motility per se but include a plethora of effects such as inhibition of cell growth, induction of morphogenesis, stimulation of T cell adhesion to endothelium and migration, enhancement of neuron survival, and regulation of erythroid differentiation. Furthermore , the discoveries of the HGF receptor as Met, of an HGF-related factor, called HGF-like protein, and of HGF-like's receptor as Ron, a transmembrane tyrosine ki-nase similar to the HGF receptor, have added yet more levels of complexity to the nature of HGF and its now growing family. Hepatocyte growth factor is a mesenchymally derived hep-arin-binding glycoprotein that is secreted as a single-chain (pro-HGF), biologically inert precursor. Under appropriate conditions such as tissue damage (21), pro-HGF is converted to its bioactive form by proteolytic digestion at a specific site within the molecule. This proteolytic digestion may be mediated by urokinase plasminogen activator (uPA) (27) or by a protease homologous to factor XII (21). Mature HGF is a heterodimer, consisting of a 60,000 Mr alpha and a 30,000 Mr beta chain held together by a single disulfide bond. The nucleotide sequences of human, rat, and mouse HGF cDNAs also predict that both chains of HGF are encoded by a single open reading frame resulting in a 728-amino acid polypeptide. The alpha chain of HGF contains a hairpin loop (of ~27 amino acids) at its amino terminus and four unique domains known as kringles, while its beta chain contains a serine protease-like structure (26). (For in depth review, see references 20 and 30.) The kringle motif, an 80-amino acid double-looped structure formed by three internal disulfide bridges, was first described for many of the enzymes involved in coagulation and fibrinolysis. Understandably, HGF resembles several coagulation/fibrinolytic related proteins such as plasmino-gen, but these proteins have no known growth potentiat-ing activity comparable to HGF. Conversely, HGF has no known protease activity, since the characteristic amino acids normally present in the catalytic site of serine pro-teases have been mutated in HGF, while the consensus sequences which normally surround them still …


Investigation showed that there exist identity and differences of youngsters sexual offenders in the eastern part in our country.Their common causes are unhealthy society tendencies and the impact of anomie and moral society in transition.Besides,more are from lack of sex education.Therefore the suppression and prevention of youngsters sexual crime must start from problems at its source,it is necessary to set up schools,families,society three-dimensional defense system and start youth self-immunization.


Introduction The basic function of the NAD (nicotinamide adenine dinucleotide) for human is to release energy from nutrients in our diet through conversion between NADH (reduced form) and NAD(oxidized form) in various redox reactions to form adenosine triphosphate (ATP) for supporting all cellular activities and functions. The intracellular NAD/NADH ratio, defined as the redox state, reflects the fundamental balance of the cellular oxidative-reductive reactions associated with the energy production [1]. In addition, NAD also involves in many important enzyme reactions, which mediates various biological processes including the metabolic signaling, calcium homeostasis, and aging or cell death [2-3]. Despite their important roles in cellular metabolism and regulation, it is unfortunate that there is no in vivo approach available for non-invasive assessment of NAD contents and redox states, in particular, in human brains. In this study, we exploited a novel P MRS approach recently developed in our lab to directly measure the NAD contents and the NAD/NADH redox ratio in healthy human brains at 7T. Methods Eleven healthy volunteers (Age: 21-64 years, 6M/5F) participated in this study. All MR measurements were conducted at 7 Tesla/90 cm bore human scanner (Siemens) with a surface coil probe placed over the visual cortex for data acquisition. This probe consists of a quadrature H coil for anatomic imaging and B0 shimming and a single loop P coil (Dia. ≈ 5cm) for collecting P MR spectroscopy data. The P spectra were obtained using pulse-acquire sequence, 300μs hard pulse for excitation with optimized pulse power and flip angle, 3s repetition time and 320 total scan number in all subjects. A novel quantification method capable of simulating and/or fitting the spectrum of all α-ATP, NAD and NADH resonance peaks at a given magnetic field strength was applied. The absolute concentrations of α-ATP, NADH and NAD in each subject were determined by comparing the integral of these resonances with that of α-ATP, in which its concentration was set to 2.8mM as an internal standard [4]. The ratio of NAD/NADH and the total NAD content ([NAD]total=[NAD ]+[NADH]) in the brain tissue were also be determined. Results Figure 1 displays a typical in vivo P spectrum of human visual cortex obtained in a representative subject. Excellent sensitivity and spectral quality achievable at 7T ensured the reliable detection and quantification of the NAD signals in vivo. The total signals of α-ATP, NAD and NADH determined by the model fitting matched well to the original P signals with very low residual, thus, the individual fitting components provided quantitative measures of the intracellular NAD contents and redox ratio with the values of [NAD]=0.30mM, [NADH]=0.08mM, [NAD]total=0.38mM and NAD /NADH redox state of 3.51 obtained in this subject. When the absolute concentrations of NAD, NADH and total NAD in different subjects were plotted against their ages as shown in Fig. 2, strong age-dependent relations were observed in individual subject data (open symbols) as well as in grouped data (filled symbols). We found that the NADH increases and NAD declines with the rise of the subject's age, thus, a profound reduction in the NAD/NADH redox state was clearly evident in the healthy human brains with normal aging. We also found that the total NAD level was slowly declined in older people's brain. Discussion and Conclusion The present study, for the first time, reported following intriguing findings: i) it is feasible to robustly measure and identify the in vivo P MRS signals of the NAD and NADH in human brain at 7T; ii) the knowledge regarding the NAD and its redox state in human brain, which is not available in the literature, can now be readily and non-destructively obtained; and iii) the intracellular NAD concentrations and NAD/NADH redox state are strongly age dependent in the healthy human brains. The agerelated NAD and redox changes observed in this study are likely the indications of deteriorating cellular metabolic activities and functions occur during the aging process. Further study is needed to underline their relations with the anticipated morphological, neurochemical or metabolic changes found in aging brains [5-6]. We conclude that the newly developed in vivo P MRS approach provides new opportunities for studying the central roles of the NAD and its redox in human health and diseases. The same approach can be readily extended to other organs beyond the brain.


As the concern for the environment is increasing day-by-day, a shift in consumption pattern can be witnessed among consumers. They are following sustainable consumption practice. The consumers are demanding the products which are pro-environmental in product production process, consumption process, communication process as well as disposable process. The manufacturers have also responded to the demands of consumers. The concept of the green marketing is evolving over a period of time in India and manufacturers are following green practices to make their product greener. The current study has focused on understanding the impact of demographic variables (gender, age, income, and education) on purchase of the green products among Indian consumers. The research methodology followed a survey method to collect data from 509 respondents from Delhi-NCR. Analysis of Variance (ANOVA) and Multianalysis of Variance (MANOVA) was conducted to test the hypotheses and results were interpreted. Limitation of the study was discussed and future research scope was discussed.


Particle swarm optimization(PSO) is generic heuristic algorithm based on swarm intelligence.It is applied to many practical continuous optimization problems.But it is not extended to solve discrete and combinatorial optimization problem effectively.For solving the problem,particle's position,velocity and their operation rules are redefined,at the same time,this inertial operator is put forward which has the self-adaptive ability.For the past discrete algorithm's shortcomings in damaging the path caused by adjusting the overall formation,this new algorithm adds a local adjustment strategy,then forming a local adjustment discrete PSO algorithm.Through the test on Ch31 and eil51,it proves new algorithm in solving TSP is feasible.


During the late 1930s and the early 1940s, a particularly productive period in his scientific life, Conrad Hal Waddington (1905–75) started to construct a new synthesis between genetics, embryology and evolution. In the 4 years between 1939 and 1943, before he became involved in military activity during the Second World War, he published two substantial books and several seminal papers, all of which were explicitly geared towards constructing of an integrated view of biology. 'The Epigenotype', 1 published in 1942 in the semi-popular science journal Endeavour, is one of these papers. In it, Waddington presented and developed some of the ideas that he had already discussed in his books, and also defined, albeit informally, a new domain of research, epigenetics—the study of the causal mechanisms intervening between the genotype and the phenotype. Today, epigenetics is a very broad field of study, covering many aspects of biology, including morphogenesis, cell heredity, transgenerational epigenetic inheritance, and the evo-devo approach to evolution that Waddington investigated though his genetic assimilation experiments. In this commentary, we briefly discuss one particular aspect of Waddington's epigenetic approach, the network-oriented view that he put forward in the 1942 Endeavour paper, 1 and the way in which this network view, Waddington's epigenotype, is conceived today.


After in-depth study on the HLS,it is found that HLS has the problem in the video streaming transmittedrepeatedly aspect of the index file in live streaming process. Specifically addressed the interaction process between theserver and the client,for using network monitoring software,video streaming index files are detected that there is a largeredundancy when the server transmits to the client in the interactive process,resulting in the increased network bandwidthoverhead. A viable improvement program is proposed,to add a #EXT-X-MEDIA-SEQUENCE-LAST tag in the.m3u8 file,making the label identified by the server and the client. Through comparative analysis,the occupancy rate of the networkbandwidth,the occupancy rate of the network bandwidth are significantly reduced in the improved program,verify thefeasibility of the improved program.


In this paper, we calculate the quantum anomaly for the longitudinal and the transverse Ward–Takahashi (WT) identities for vector and axial-vector currents in QED2 theory by means of the point-spli...


We determine the probability that a random polynomial of degree n$n$ over Zp${\mathbb {Z}}_p$ has exactly r$r$ roots in Qp${\mathbb {Q}}_p$ , and show that it is given by a rational function of p$p$ that is invariant under replacing p$p$ by 1/p$1/p$ .


Optimization over $l\times m\times n$ integer $3$-way tables with given line-sums is NP-hard already for fixed $l=3$, but is polynomial time solvable with both $l,m$ fixed. In the {\em huge} version of the problem, the variable dimension $n$ is encoded in {\em binary}, with $t$ {\em layer types}. It was recently shown that the huge problem can be solved in polynomial time for fixed $t$, and the complexity of the problem for variable $t$ was raised as an open problem. Here we solve this problem and show that the huge table problem can be solved in polynomial time even when the number $t$ of types is {\em variable}. The complexity of the problem over $4$-way tables with variable $t$ remains open. Our treatment goes through the more general class of {\em huge $n$-fold integer programming problems}. We show that huge integer programs over $n$-fold products of totally unimodular matrices can be solved in polynomial time even when the number $t$ of brick types is variable.


Punning is one of the most common rhetorical devices used in English headlines.Yet a pun's double meanings and special modes of expression make its translation a tough job.This paper studies the feasibility of translating puns based on Conceptual Blending Theory and,with explicit elaboration,concludes that such a cognitive theory can be extremely helpful during the course of translation.


An attempt has been made to explain to the scientific and technical establishment the fact that the fuzzy controllers with input/output parameters represented by set of precise terms automate control objects, whose operative algorithm is presented verbally as a unique experience of experts in the domain, in simpler way, with higher speed, slighter error and less costs as compared with the standard fuzzy controllers.


Background: Despite the global efforts to control tuberculosis, it remains a common, life-threatening infectious disease. Tuberculosis can lead to hypercoagulability, increased venous stasis, and endothelial dysfunction, thus increasing the susceptibility to venous thromboembolism (VTE). However, few studies have assessed the epidemiology of the association between tuberculosis and VTE. We recently completed a study to address this coexistence. Methods: Medical records of hospitalized tuberculosis patients at the National Research Institute of Tuberculosis and Lung Disease (NRITLD) from January 2001 to December 2008 were reviewed. Patients with coexisting VTE were selected. Presenting signs and symptoms, and co-morbidities in these patients were studied. Results: 3293 tuberculosis patients were hospitalized, of whom 46 had coexisting symptomatic VTE (31 males, 15 females, mean age: 53.4 ± 19.6 years; DVT: 26, PE: 13, DVT+PE: 7). Of these 46, 29 had a primary diagnosis of tuberculosis, and symptomatic VTE evolved during hospitalization. None of the 29 patients had received VTE thromboprophylaxis. Of the remaining 17 patients with TB and VTE, 15 were tuberculosis patients undergoing outpatient treatment who were admitted to hospital with a primary diagnosis of VTE. Two other patients were initially hospitalized because of VTE, and coexisting tuberculosis was discovered during hospitalization. Mean hospitalization length was 28.6 ± 14.0 days. Four patients died during hospitalization. Median survival time of the patients was 407 days (95% CI: 269.7544.4 days). Conclusion: VTE is an important co-morbidity of tuberculosis patients. Most of our patients developed in-hospital VTE while they were not receiving thromboprophylaxis. Guidelines to institute VTE prophylaxis in TB patients should be considered. Follow-up for VTE signs and symptoms in TB patients is warranted. Tuberculosis (TB) is a serious potentially-treatable infectious disease. Even though the epidemiology and at risk population are not identical in the developed and developing countries, it is a major health problem in both settings. (1) In the early 1940s, it was thought that venous thromboembolism (VTE) is rare in TB patients. (2) However, they are predisposed to venous thromboembolism (VTE) due to several pathophysiologic mechanisms, affecting all three parts of the Virchow's Triad. Only a few studies have addressed this issue. Therefore, we recently investigated the coexisting venous thromboembolic events among the tuberculosis patients of the National Research Institute of Tuberculosis and Lung Disease (NRITLD), a WHO-collaborating university-affiliated teaching hospital that provides specialized care for TB patients in the Middle East. (6)


Since the discovery of the obese (ob) gene and its protein product leptin, there has been a great deal of interest in the relation between leptin


Mammalian cells are widely used for the production of therapeutic recombinant proteins, as these cells facilitate accurate folding and post‐translational modifications often essential for optimum activity. Targeted insertion of a plasmid harboring a gene of interest into the genome of mammalian cells for the expression of a desired protein is a key step in production of such biologics. Here we show that a site specific double strand break (DSB) generated both in the genome and the donor plasmid using the CRISPR‐Cas9 system can be efficiently used to target ∼5 kb plasmids into mammalian genomes via nonhomologous end joining (NHEJ). We were able to achieve efficiencies of up to 0.17% in HEK293 cells and 0.45% in CHO cells. This technique holds promise for quick and efficient insertion of a large foreign DNA sequence into a predetermined genomic site in mammalian cells. Biotechnol. Bioeng. 2015;112: 2154–2162. © 2015 Wiley Periodicals, Inc.


This study was conducted with fifth and sixth grade children. It had two main goals: to identify and develop modelling skills, and to change children's conceptions of the role of mathematics in analysing situations and solving problems. A specia l sequence of ten modelling tasks was designed with these two goals in mind. This article reports part of the findings, focusing on the effect of the tasks on children's conceptions with regard to the different uses of mathematics. Specifically, tasks that involve the construction of decision criteria promoted awareness of the freedom in making these choices, and the importance of available mathematic al models. Other tasks involving scientific phenomena facilitated understanding of the model fi tting process, and the predictive role of mathematics in situations of this type.


A modular multilevel converter (MMC), which provides output voltages with low harmonic contents, gives a simple structure without needing several isolated DC power supplies. However, an MMC suffers from sheer number of switches and associated electronic circuits because it requires the addition of two half-bridge submodules to one leg of the converter to add only one voltage level to the output voltage waveform. This paper proposes a granular multilevel converter (GMC) that provides required number of voltage levels with a reduced number of power switches and associated electronic circuits. In the proposed GMC, the addition of one submodule doubles the number of output voltage levels. For a specific number of submodules, the charge control algorithm of the capacitors and the switching table of the proposed converter are described. The proposed control algorithm ensures the voltage control of submodule capacitors using hysteresis controllers and the data from the transducers of the line current and capacitor voltages. The proposed converter structure, charge control algorithm, and switching table are validated by simulation case studies.


Indonesia, like many other countries in the Asia Pacific region, has always been interested in US political development. Indonesians collectively felt proud as they watched Barack Obama become President. Discusses the four years Obama spent in his childhood in Jakarta. He did not go to an international school but to local primary schools. The impact in Indonesia of the election of Barack Obama is discussed, in the light of the Indonesian reaction to the terror attacks in September 2001 and American reaction to the threat posed by Muslim extremists. Indonesian hardliners used this as an excuse to justify their stance against democracy.


In order to achieve the goal of a safe,economical and simplicity during the construction in the deep excavation design,this paper discusses several improper designs of the supporting structure connection details.The optimized connections are proposed based on the structural analysis.The improved connection not only reduces the complexity as well as the potential risks in the construction but also result in a cost saving in the materials.


With rapid developments in big data and artificial intelligence technologies, materials informatics has become a new paradigm of materials science and engineering. In this review, the progress of modeling studies of phase stability in alloys is presented, with particular attention given to the development of the paradigm from traditional computational materials science (CMS) to materials informatics. The features of CMS models for phase stability studies are compared with those of data-driven approaches. The advantages of data-driven modeling in the framework of materials informatics are revealed. The approaches for developing interpretable machine learning, which has been mainly integrated with the developed CMS models and material science theories, are also discussed. Finally, the prospects for data-driven materials design based on the stability control of the dominant phases with regards to performance are proposed.


For the trust region method based on the new conic model to solve unconstrained optimi-zation problems,a new horizon vector of the conic model is proposed.The numerical results show that the above method is more improved.


The purpose of this paper was to develop a radio-frequency identification (RFID)-based autoscoring system for the Progressive Aerobic Cardiovascular Endurance Run (PACER) and 6-min walk tests, which are two popular aerobic fitness tests. RFID is a commonly used technology for tracking and tracing, and is replacing the barcode in various industries. However, its measurement advantages have not yet been taken up in the field of physical fitness testing, in which human errors often occur due to the difficulty in tracking and scoring test takers simultaneously. An RFID-based automatic scoring system can eliminate errors by automatic tracking and scoring. A preliminary system was developed for the PACER and 6-min walk test scoring, and it was evaluated during pilot testing. The RFID-based system is a successful example of the application of RFID technology to the field of physical fitness testing, showing great potential in physical fitness and activity tracking and scoring. The proposed system enables the mass testing of many students or examinees accurately, and it could significantly reduce the burden of test administers. This system also has great potential to extend into the physical activity monitoring and promotion area.


THE attitude of the n~n-handi~apped toward the handicapped m society, in the writer's opinion, places the latter in a minority status not greatly different from the status of more commonly identified minority groups. Although great efforts have been made to improve the social position as well as the physical and psychological conditions of the handicapped, it would appear that further gains might be achieved through the application of sound sociological procedures.


Although the excellent properties of borides have attracted the attention of the industry, their limitedpreparation process and difficult-to-remove impurities have prevented them from exerting their fulleffectiveness. However, it is very difficult to separate AlB12 and Al2O3 prepared by self-propagating hightemperature synthesis. This study is the first time to separate the two by electrolysis process and observetheir electrolytic behavior. The results show that Al2O3 is converted into micron-sized aluminum during theelectrolysis process, while AlB12 still exists intact. This result provides a novel idea for the future purificationof borides containing Al2O3 impurities


Objective To compare the effects of surgical versus non-surgical treatment for deep vein thrombosis(DVT) of lower extremities.Methods One hundred and twenty-seven proximal or proximal and distal combined DVT patients were divided into surgical treatment group(67 patients) and non-surgical treatment group(60 patients).The circumference of lower limb involving DVT in all patients were 2cm more than that of the other limb.The courses were from 8 hours to 90 days.The patients in the surgical group received thrombectomy,balloon venoplasty,and stent placement after placement of inferior vena cava filters.Two groups received anticoagulation and thrombolysis via limbs involving DVT.Color Doppler sonography and the edema fadeaway were used to evaluate the treatment effects.Results The effect of surgical treatment was superior to non-surgical treatment.The effects of acute and subacute patients in surgical group had no statistical difference,but that of acute and subacute versus chronic patients had statistical difference.The effects of acute patients in two groups had no statistical difference,but surgical treatment was superior to non-surgical treatment for subacute patients.Conclusions Non-surgical treatment may be proper for acute DVT of lower extremities.Surgical treatment is superior to non-surgical treatment for subacute proximal or proximal and distal combined DVT patients who received non-regularizing treatment in acute stage.


Aim of the present investigation is to carry out the macroscopic , anatomical, powder microscopic and phytochemical study of the leaves of Syzygium caryophyllatum. Microscopic study revealed the presence of palisade cells, parenchyma cells with tumor, vascular strands, paracytic stomata. Preliminary phytochemical screening showed presence of flavonoids, phenolic compounds, alkaloids and saponins. Pentacyclic triterpenoid saponins were absent.


Describes the development of a microcomputer-based intelligent system for motion control. The system, utilizing intelligent software is capable of implementing several real-time controls such as speed, acceleration, position and others. The system can control three axes movement and provides five modes of motion such as jogging, independent axis positioning, point-to-point positioning, linear interpolation, and linear and 2-D coordinated motion. This system has been tested successfully on various applications including fan and stepper motor control.


The main goal of each company is to optimize the company's profit because it will have an impact on business continuity and the most important element in achieving this goal is the existence of inventory in the form of goods. Then a good company is a company that has a good and neat system in terms of collecting data on the production of goods and their inventory. This study aims to determine the inventory of goods available in Company X and improve the data input system at the company.