E ffective peer review of scientific manuscripts is essential because publications are a central component of advancing science and an individual author's academic career. The importance of this process is underscored by the presence of the International Congress on Peer Review in Biomedical Publication and the devotion of an entire issue of the Journal of the American Medical Association to the peer review process [I]. Because a manuscript reviewer may have an unconscious or overt bias against an individual or his or her institution, it seems intuitive that withholding the author's identity could provide less biased reviews [21. In addition, blinding the reviewers to the author's identity may result in improved quality of reviews [3]. The purpose of this editorial is to demonstrate how authors may inadvertently unmask themselves, thereby precluding a true blinded review. First, use of the first person. The term "we have shown that. . ." should not be used. Instead, it should be changed to "Jones et al. have shown that Second, excessive citations from a single author or institution. Citations that support critical issues are important and should be referenced. However, using more than three or four references from the same individual is rarely necessary. When the bibliography reads like a curriculum vitae, it becomes painfully obvious to the reviewer who the author is. A little bit of humility goes a long way. Third, citations that are in press. Because the reviewer has no way of reading a manuscript that has not yet been published, quoting references that are in press is rarely justified and almost always reflects work by the same author or the same institution. Fourth, inappropriate citations of abstracts. Because abstracts are not subjected to rigorous peer review, they should be referenced only when peer-reviewed publications on the same topic do not exist. It is unnecessary to cite an abstract that represents the paper that is submitted because this will clearly reveal the author's identity. Fifth, use of the author's initials in the manuscript. For example, "Three observers (SLK, GMR, and WSB) retrospectively evaluated These initials can be inserted after the manuscript is accepted. (Note: AiR style precludes the use of initials for observers or patients. This fifth point is included for the benefit of contributors to journals other than the AiR.) Sixth, acknowledgments. Although it is important to acknowledge those individuals who have helped prepare a manuscript, the acknowledgment.s can be written after an article is accepted. Over time, journal readers have come to learn the names of the secretaries, assistant,s, and photographers of many prolific authors. Seventh, failure to remove names of institutions from images and drawings. This point is self-explanatory: Institutional names should not be included. Eighth, use of figures from previous publications. Although most journals require original (not previously published) figures, some authors use the same figures in different publications, which clearly reveals the author's identity. In conclusion, by following these simple guidelines and avoiding the examples described, authors will minimize the potential of having their manuscripts evaluated by "unblinded" reviewers.


During the conflicts in Afghanistan and Iraq, the media have called attention to post-traumatic stress syndrome, concussive injuries, and the development of improved prosthetic devices, but PTJ 's special issue on military rehabilitation broadens our perspective to consider such topics as depression, sleep deprivation, transition back to community, and occupation. This issue also sheds light on the important role that physical therapists in the military play in diagnosing and treating a variety of musculoskeletal conditions.

Although this issue focuses on the armed services in North America, the guest co-editors, Lt Col John Childs and Dr Alice Aiken, and I believe that the findings are relevant to military personnel around the world—and to civilians as well. Several models of health care delivery presented in this issue may serve as models for effective accountable care organizations and medical homes and merit investigation. I thank Lt Col Childs and Dr Aiken for "joining forces" to create this issue. The idea began with a discussion with Dr Aiken at the World Confederation for Physical Therapy conference in June 2011; when you read their editorials, you will understand their passion and the timeliness of the topics.

In his editorial, Lt Col Childs remarks, " Regardless of your political leanings, war is the closest thing to hell on Earth …." This is a perfect opening for us to contemplate the life of someone who chose an alternate path to the military for his public service. As a Quaker, John "Jack" …


The paper "Assimilation of sea surface salinities from SMOS in an Arctic coupled ocean and sea ice reanalysis" looks at the effect of assimilating the latest version (V3.1) of SMOS surface salinity data into the Arctic region. It does this by comparing the results to model runs which either did not assimilate SMOS data, or used an earlier version (V2.0) of the data. Validation was done against a variety of in-situ sources. The broad conclusion is that the V3.1 data does bring some benefits.


Understanding possible interactions of drugs and the factors that command such interactions could be helpful to control their disadvantageous effects upon human health. In this study, volumetric properties for the solution of diclofenac potassium (DP), a non-steroidal anti-inflammatory drug (NSAID), were investigated for the first time to look into its molecular interactions at four different temperatures varying from 298.15 K to 313.15 K at 5 K intervals in water as well as aqueous hydrotropic agent urea (1M) solutions. Experimental density data obtained using a pycnometer have been taken to estimate apparent molar properties, i.e., limiting apparent molar volume (〖V_ɸ〗^0), apparent molar volume (V_ɸ), limiting apparent molar expansibility (〖E_ɸ〗^0) and apparent molar expansibility (E_ɸ). The results obtained were discussed in terms of solute-solvent and solute-solute interactions in the studied systems. The obtained results from volumetric data were explored in terms of the existence of solute-solvent interactions in aqueous systems of drug solutions.


Abstract Background Rapid initiation of antiretroviral therapy (ART), i.e. within 72 hours of diagnosis, in people living with HIV (PLWH) has shown improved viral suppression, medication adherence, and retention in care, compared to deferral until initial labs have resulted. More real-world experience with rapid ART programs is needed, however, particularly among clinics in resource-limited settings that serve a complex and largely uninsured or underinsured population, such as the HIV clinic at SUNY Downstate Medical Center. In 2017, the clinic implemented rapid ART in select PLWH. Methods This was a single-center retrospective chart review of patients seen at our HIV clinic between January 2015 and June 2021. Patients were included if they were ART-naïve or off ART for > 3 months. Exclusion criteria included baseline undetectable viral load (VL) and perinatal HIV infection. Patients were assigned to standard or rapid start groups based on time from intake to initiation of ART. The primary outcome was proportion of patients with VL < 50 copies/mL at week 52. Secondary outcomes were proportion of patients with VL < 200 copies/mL, retention in care, and mean weight change from baseline, all at week 52; time from intake to ART; and time to viral suppression. Results As shown in Table 1, of the 190 patients that were included, 133 were rapid start while 77 were standard start. 103 patients had baseline resistance data; only 1 had integrase stand inhibitor resistance. Median time to ART was 0 days and 2.5 weeks in the rapid and standard groups, respectively. The most common initial regimen was BIC/FTC/TAF in both groups (49.6%, 31.2%). As described in Tables 2 and 3, 62.1% and 73.7% of patients had VL < 50 and < 200 copies/mL at week 52, respectively. Nearly 73% of patients remained in care at week 52, with similar rates between groups. Time from ART to viral suppression was similar between groups. Conclusion Rapid ART was well-tolerated but resulted in similar viral suppression and retention in care at week 52 compared to standard ART. However, rapid ART resulted in quicker viral suppression, although further evaluation of the clinical impact of this finding is needed. This study highlights the need for a multifaceted approach to engaging patients with HIV throughout the care continuum to ensure retention in care. Disclosures All Authors: No reported disclosures.


The U.S. Preventive Services Task Force updated its recommendation on medications to reduce breast cancer risk. The Task Force recommends that clinicians engage in shared, informed decision making ...


Breast cancer remains the second leading cause of cancer-related death in women, in large part due to distant metastasis to organs such as bone, lung, liver, and brain. Our laboratory has demonstrated that the IL-6-family cytokine oncostatin M (OSM) increases circulating tumor cell (CTC) numbers and metastases to lung in vivo, and that OSM stays active when bound to proteins in the extracellular matrix, thus "bioaccumulating" in the tumor microenvironment. These published findings are supported by our results demonstrating that OSM strongly promotes expression and secretion of IL-6 from breast cancer cells. Interestingly, the increased production of IL-6 by OSM occurs only in estrogen receptor-negative (ER-) cells. It is well known that patients with ER- breast cancer, specifically triple negative breast cancer (TNBC; ER- PR- HER2-), have limited therapeutic options. However, the divergent role OSM plays in ER+ and ER- breast cancer and the mechanism by which this occurs has yet to be fully understood. Thus, we aimed to fully elucidate the difference between OSM in ER+ versus ER- breast cancer. First, we performed RNA-Seq analysis on OSM-treated human ER+ T47D cells and ER- TNBC MDA-MB-231 cells and discovered significant differences in gene expression between both cell lines upon treatment with OSM, including alteration in DNA-replication and cell cycle pathway genes. Next, to better understand the mechanism by which OSM-mediated IL-6 secretion is repressed, we utilized a computational modeling approach and evaluated the direct inhibition of STAT3 and ER to identify theoretical dimerization complex for future studies. This research aims to elucidate the unique role OSM plays in ER+ and ER- breast cancer and will provide a molecular understanding of how this occurs and will provide detailed information on which patients will benefit most from anti-OSM therapeutics.
 Citation Format: Cody L. Wolf, Ken Tawara, Cheryl L. Jorcyk. Examining the differential roles of OSM and IL-6 in varying subtypes of breast cancer for novel therapeutic treatment [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 1244.


Ernst Doblhofer's Zeichen und Wunder; die Entzifferung verschollener Schriften und Sprachen (Vienna: Paul Neff Verlag, 1957) is the history of the decipherment of ancient scripts; and it ranges from the Rosetta Stone to the yet undeciphered Etruscan, Indus, and Easter Island inscriptions. Well illustrated and fully documented with references to the basic monographs and articles in scholarly journals, Doblhofer's text is nevertheless in a light, almost journalistic style. He deals not only with the language of peoples who developed a high level of culture, but also with the languages and scripts of more primitive civilizations. As a text for courses in the history of books and writing, Zeichen und Wunder deserves a high place on the reading lists. At the same time, however, the rapid advances being made in many fields covered by this book suggest the need for frequent revision of this book.


This study was designed to develop an environmentally friendly wood stain derived from laurel (Laurus nobilis L.) and determine the color stability of this stain when exposed to UV light irradiation. Wood stains derived from L. nobilis were prepared from aqueous solution with alum and iron mordant mixtures. Scots pine (Pinus sylvestris L.) and Turkish oriental beech (Fagus orientalis Lipsky) wood specimens were used as staining substrates. After treatment with the stain, the wood panels were exposed to UV light irradiation for periods of 100, 200, and 300 hours. Results showed that wood stain derived from laurel (bay) extract provided some color stability after UV irradiation.


Recent observations of magnetic fluctuation activity in the Mega Ampere Spherical Tokamak (MAST) reveal the presence of plasmas with bands of both low and high frequency magnetic fluctuations. Such plasmas exhibit a spectrum of low frequency modes with adjacent toroidal mode numbers, for which the measured frequency is near the Doppler shifted rotation frequency of the plasma. These are thought to be tearing modes. Also present are a spectrum of high frequency modes (e.g. Alfvén, fishbone and/or ICE). The frequency and mode number of the tearing mode and its harmonics is identical to the frequency and mode number splitting of the high frequency MHD activity, strongly suggesting that the high frequency splitting is produced by modulation of the high and low frequency modes. We describe a strong modulation model, in which the nonlinear terms are fitted to produce the amplitude envelope profile of the tearing mode. A bispectral analysis proves that the low frequency modes are indeed in phase with the fundamental, while Fourier-SVD mode analysis confirms the mode numbers are toroidal harmonics. Employing this model, the sideband amplitude profile of the high frequency modes is predicted, and found to be in good agreement with experimental observations. Also, toroidal mode number splitting of the high frequency activity matches the mode number of the tearing mode. Weak evidence is found to indicate the Alfvénic sidebands are in phase with the Alfvén eigenmode fundamental. The findings support predictions of a strong modulation model, and suggest a need to further develop nonlinear MHD theory to predict the amplitude of coupled sidebands, and so corroborate the observed nonlinear plasma response.


Objective To observe the effects of asthmatic children treated by inhaled salmeterol xinafoate and fluticasone propi-onate powder. Methods One hundred and fourty cases of moderate and severe asthmatic children were treated in non- acute period aged from 4 to 14 years by inhaling salmeterol xinafoate and fluticasone propionate powder, compared with control group treated by flu-ticasone propionate in 106 cases, and the pulmonary function was monitored simultaneously. Results The total effective rate of the treatment group and control group were 99. 3 % , 99. 1 % , respectively.The pulmonary function indexes such as the first one second expiration volume(FEV1), flow velocity of 50 % expiration vital capacity(FEF50%), peak expiration velocity(PEF1) after being treated 4 months was improved significantly compared with those before treatment.The difference between them was statistically significant (P0.01).Conclusions It is significantly effective, safety,and convenient in inhalation with little side- effects in treatment of asth-matic children by inhaling salmeterol xinafoate and fluticasone propionate powder.


The invention relates on the one hand to prevent to a method for weaving wefsels on a weaving machine, warbij these fabrics include a plurality of warp thread systems, wherein at least two adjacent warp thread systems in each of these at least two adjacent kettinggarenstels at least two pile warp yarns having different properties, and wherein in each of said kettinggarenstels the pile warp yarns according to an alternating pattern in the tissue to be ligated figure-forming? and non-figure-formingly inwoven be or rafts along the fabric, in which a lower and an upper fabric (20), (10) are woven according to a face-, and said two adjacent warp thread systems, each having the same at least two pile warp yarns (17), ( 18), (21), (22), (23), (24), (25), (26), warbij when one pile warp yarn in the first warp thread system (17), (21), (23), ( 25) in case of non-body-shaping in the upper fabric (10), respectively, under the fabric (20) is smooth or is inwoven, the corresponding pile warp yarn from the other kettinggarenstels (17), (21), (23), (25)


Objectives: To assess the alcohol consumption, tobacco addiction and psychoactive substance use (PSU) of people living with HIV (PLHIV). Design: Cross-sectional study in an HIV outpatient unit. Methods: Autoquestionnaire systematically proposed to all patients during their usual clinical care visit during a 6-months period, for alcohol (AUDIT test), tobacco (Short Fagerstrom Test) and PSU (ASSIST V3.0 test). Results: Of 1334 distributed questionnaires, 1018 PLHIV responded: 76.8% were men [528 patients were MSM), and the median age was 49 years (interquartile range: 42–46). A prevalence of excessive alcohol drinking was found in 22% [95% confidence interval (CI) 19.5–24.7%] and 44.6% (CI 41.5–47.7%) were current smokers, with high dependence in 29.1% (CI 24.9–33.7%). The prevalence of PSU was 37.8% (CI 34.8–41%) in the past 3 months: cannabis 27.7%, poppers 16.4%, cocaine 8.9%, psychotropic medications 7.1%, gamma-hydroxybutyrate/gamma-butyrolactone (GHB/GBL) 4.7%, stimulants 3.1%, synthetic cathinones 2.7%, hallucinogens 1.5%. In the past 3 months, PSU was more prevalent in MSM than in non-MSM patients (46 versus 30%, P < 0.001). MSM consumed significantly more inhaled solvents (poppers) 31.0 versus 1.1%, GHB/GBL 7.8 versus 0.8%, stimulants 5.0 versus 1.1%, synthetic cathinones 4.9 versus 0.3%, and hallucinogens 2.3 versus 0.5%. Conclusion: Given the high prevalence of PSU and other addictions (alcohol and smoking) among PLHIV, and particularly among MSM, a systematic screening of PSU and other addictions should be part of routine clinical care.


A new approach based on the Partial Least Squares (PLS) and Wavelet Transform is presented for the industrial process monitoring. A different scheme for applying PLS for multiple faults diagnosis is used in this approach. Because of multi-scale nature of the variable measurements in the most of industrial processes the Discrete Wavelet Transform (DWT) is applied to extract the multi-scale features of these measurements. Comparison of the ability of this MultiScale PLS (MSPLS) algorithm with the PLS to diagnosis the multiple faults in the Tennessee Eastman process (TEP) benchmark, demonstrates the efficiency of the proposed approach and indicates that this MSPLS algorithm can be useful for process monitoring and detection and diagnosis multiple faults.


The basic law of this country, the common law, has dealt very little with the complex issues of human rights presented by randomization. The fundamental legal approach to this subject would start w...


The Dulong Sn-Zn polymetallic deposit,Yunnan Province,is one of the largest cassiterite-sulfide deposits in China.Being lack of the accurate and reliable geochronological data,the genesis of this deposit is controversial greatly,so that it is very serious to restrict the further development of the geological prospecting. This paper has reported the U-Pb isotope dating of cassiterite by the method of in-situ LA-MC-ICP-MS from the Manjiazhai section of the Dulong ore-field. The result showed that the206Pb /207Pb-238U /207Pb isochron ages of cassiterite samples DL12-716,DL12-722 and DL12-740 were 89. 2 ± 4. 1Ma( N = 22,MSWD = 4. 5),88. 0 ± 1. 6Ma( N = 24,MSWD = 2. 3) and 87. 2 ± 3. 9Ma( N = 31,MSWD = 14) respectively,and the207Pb /206Pb-238U /206Pb concordia ages of the corresponding cassiterite samples were 96. 6 ± 3. 5Ma( MSWD = 8. 1),93. 6 ± 1. 6Ma( MSWD = 5. 8) and 82. 0± 2. 5Ma( MSWD = 11) separately. Combining with geology and previous petrogenetic-minerlization geochronology,indicated that the tin minealization of this deposit might mainly be in the Late Cretaceous,which related closely to the later Yanshanian magmatic hydrothermal events. Meanwhile,the basis of the geological facts revealed that the later Yanshanian magmatic hydrothermal events were the key factor of the W-Sn polymetallic deposit mineralization in the Laojunshan area. Moreover,regional geology and geochronology further suggested that there were Late Cretaceous larger-scale granitic magmatism and relative tin mineralization events in the southeastern Yunnan.


In the determination of SiO_2 in furnace water,the reductant of silicon-molybdenum blue colorimetric method, 1-2-4 sulfonic acid was replaced by ascorbic acid. The optimum conditions has been obtained and the results was satisfactory.


In this paper,the brief development history of basin simulation systems at home and abroad is introduced systematically.On this basis,the present developing situation of both geological and mathematical models for basin simulation is analyzed,especially that of geohistory,thermal history,hydrocarbon generation history,hydrocarbon expulsion history and hydrocarbon mingration and accumulation history "five histories" models for hydrocarbon accumulation dynamics.It is suggested that five difficult problems remain to be solved about basin simulation technology,that is,the organic unity of basin dynamic models and hydrocarbon accumulation dynamic models,the setablishment of dynamic balance models and corresponding mathematical models for 3 D geologic bodies,the correct modeling of the paleohydrodynamic process of basins,the full three dimensionation of each models for hydrocarbon accumulation dynamics and the solution of partial differential equations for variable meshes.It is considered that the developing trends of basin simulation technology in the next decade are as follows: 1) the full 3 D hydrocarbon basin dynamic simulation system based on basin dynamic evolution will be ste up and perfected gradually; 2) the basin dynamic simulation system supported by large scale exploration data bases will become powerful tols for hydrocarbon exploration and resource prediction; 3) the hydrocarbon generation system simulation will be the important content and developing style of basin simulation; and 4) "interactive simulation","artificial interfering interface" and "synthetic evaluation" technologies will make rapid progress.


In the article research the resistance of Ukrainians to the anti-religious policy of the Bolsheviks, the first years of their stay in power. The article notes that one of the main characteristic features of the development of Ukrainian historiography at the current stage is the increasing attention of scientists to problems related to the history of church life in Ukraine. This especially applies to the Soviet period of history, when the traditional church, which used to be one of the determining factors in the development of Ukrainian society, suffered a significant blow as a result of the implementation of the anti-church policy of the Soviet government. At the same time, especially in the first decades of the existence of the Bolshevik regime, opposition to the anti-religious policy of the Bolsheviks on the part of the Ukrainian population was quite noticeable. This aspect, in our opinion, needs a more detailed scientific rethinking, which is aimed at this scientific article. Are shown the main directions and types of resistance, its results and consequences for the further implementation of the church policy by the Soviet authorities. It also depicts a complex of punitive repressive measures against the religious communities of Ukraine during the period under study. As a result of the conducted research, the author comes to the conclusion that from the moment the Bolsheviks came to power, their anti-church company encountered spontaneous protests from various religious communities. The protest took various forms – from ignoring and sabotaging the anti-religious initiatives of the Bolshevik government, to active armed resistance against its representatives. This, in turn, led to the intensification of the terror of the Soviet authorities against the church, which, in the end, was forced to recognize the politics and power of the Bolsheviks.


Physically Unclonable Functions (PUFs) are security primitives that provide trustworthy hardware for key-generation and device authentication. Among them, in contrast to dedicated PUFs, intrinsic PUFs are created from existing hardware components that exploit their variability through software. In this work we focus on GPUs and present G-PUF, a PUF implemented entirely in software on CUDA and hence does not require hardware modifications. Our results show that G-PUF has comparable characteristics to SRAM and DRAM PUFs in terms of uniformity 55.61% and reliability 90.09%.


Security is one of the main concerns in modern networks. Given the recent success of wireless networks, there are plenty of possibilities to attack the networks themselves [14][24] or services [28] running on these networks. Current progress in research and growing interest from the industry let also expect more and more sophisticated Ad-hoc networking solutions. Compared with security problems in conventional wireless networks 1 Adhoc networks are exposed to additional risks. In addition to that a reasonable level of security seems to be more difficult to achieve in these networks due to their dynamic and distributed nature. This paper will give an overview about basic security problems in Ad-hoc networks and the research that has been conducted in related areas so far. It presents some algorithms that can be used as building blocks for security in Ad-hoc networks. Given the constraints faced by such networks, the paper also inspects its practicability in Ad-hoc environments.


Relations between a model of the feeding activ- ity of Euphausia superba, the oceanic environment and the vertical distribution of krill around South Georgia are described. Krill with full alimentary tracts occur both above and below the thermocline, over a 20-fold range of chlorophyll concentration. Changes in chlorophyll concentra- tion, temperature, salinity and nutrients which occur down the water column appear to have no effect upon the feeding activity of krill. As the energy requirements of krill can be met with known filtration rates over the range of chlorophyll concentrations encountered, this study suggests that krill adjust their filtration rate to compensate for wide changes in chlorophyll concentration and feed throughout the water col- umn. We cannot, however, exclude the possibility that krill from all depths could have fed in the cod-end of the net in the surface layer.


The inflammasomes control the bioactivity of pro-inflammatory cytokines of the interleukin (IL)-1 family. The inflammasome assembled by NLRP3 has been predominantly studied in homogeneous cell populations in vitro , neglecting the influence of cellular interactions that occur in vivo . Here, we show that platelets boost the inflammasome capacity of human macrophages and neutrophils and are critical for IL-1 production by monocytes. Platelets license NLRP3 transcription, thereby enhancing ASC oligomerization, caspase-1 activity, and IL-1 b secretion. Platelets influence IL-1 b production in vivo , and blood platelet counts correlate with plasmatic IL-1 b levels in malaria. Furthermore, we reveal an enriched platelet gene signature among the high-est-expressed transcripts in IL-1 b -driven autoinflammatory diseases. The platelet effect is independent of cell-to-cell contact, platelet-derived lipid mediators, purines, nucleic acids, and a host of platelet cytokines, and it involves the triggering of calcium-sensing receptors on macrophages. Hence, platelets provide an additional layer of regulation of inflammasomes and IL-1-driven inflammation. and 1% Sodium Pyruvate) complemented with 500 U ml -1 rhGM-CSF at a concentration of 2x10 6 ml -1 in 6-well plates to generate monocyte-derived macrophages. Cells were harvested at day 3, counted using a hemocytometer and seeded at a concentration of 1x10 5 /well in complete medium complemented with 125 U ml -1 rhGM-CSF in 96-well flat-bottom plates and incubated overnight for experiments on the next day. human experiments) or 5x10 6 platelets ml -1 (for mouse BMDM experiments), in order to fit the macrophage:platelets proportion of 1:50 (human) or 1:5 (mouse). For the generation of supernatants from the megakaryocytic cell line MEG-01, 1x10 6 cells ml -1 were used. Next, platelets or MEG-01 were left untreated (Unstim) or incubated at 37 (cid:4) C with LPS (200 ng ml -1 ) or thrombin (1.0 U ml -1 ) for 3 hours. After stimulation, the platelet cell suspension agent Lipofectamine 2000 in OptiMEM. After 15 minutes of incubation, the empty vesicles were combined in 1:1 proportion of 4 m g ml -1 Poly(dA:dT), and further incubated for 15 minutes. The dsDNA-containing vesicles were added directly on the cell culture for a final volume of 100 m l of medium (final stimulatory concentration of 1 m g ml -1 ). Cells were stimulated for 3 hours before cell-free supernatants were harvested for cytokine measurements. mixed with the cell-free supernatant and the luminescent signal was evaluated 30 minutes later. The extracellular lactate dehydrogenase (LDH) concentrations in cell-free supernatants were assessed using the Pierce LDH Cytotoxicity Assay, according to the manufacturer's instructions. Samples were measured at an absorbance of 490 nm using a Spectra-max i3 plate reader (ThermoFisher). Control hMDMs cultured at the same conditions as the samples were lysed with the provided Lysis buffer (10x) and served as positive control for maximal LDH release. was determined to be 7 amino acids and carbamidomethylation at cysteine residues was considered as a fixed modification. Oxidation and acetylation were included as variable modifications. For the analysis, the match-between runs option was enabled.


Previous research has documented lower vaccination rates among ethnic and racial minorities as well as foreign-born people, thus raising concerns about health inequities during pandemics. We analyzed influenza vaccination rates among children with US-born parents and those with at least one immigrant parent. We found that children with immigrant parents have higher odds of receiving the influenza vaccination even after controlling for socio-demographic characteristics.


A Kane-like envelope function Hamiltonian is derived for the ${\ensuremath{\Gamma}}_{15}$ valence and ${\ensuremath{\Gamma}}_{1}$ conduction states of lattice-matched, semiconductor superlattice structures, with metallurgically abrupt interfaces. The local microscopic potential is treated as a weak perturbation on that of a reference crystal and is expressed in terms of a one-dimensional profile function, $G(z)$, which modulates the difference between the potentials of the well and barrier materials. In contrast to many previous treatments, all terms up to order $\ensuremath{\ell}=2$ in $\ensuremath{\delta}\overline{V}\ensuremath{\cdot}{(\overline{k}a)}^{\ensuremath{\ell}}$ are included, where $\ensuremath{\delta}\overline{V}$ is the typical band offset, $\ensuremath{\hbar}\overline{k}$ is the average momentum modulus of the envelope function, and $a$ is the bulk lattice parameter. Far from the interfaces, the Hamiltonian is identical to the familiar bulk Kane Hamiltonian, with the standard bulk parameters. However, the operator ordering in the valence band is revised from the commonly used Burt scheme. An operator ordering scheme has also been derived for the linear-$k$ $P$ terms that couple conduction and valence states. Expressions have been derived for the $\ensuremath{\delta}$ functionlike, and derivative of a $\ensuremath{\delta}$ functionlike, interface terms. These are off-diagonal and diagonal, respectively, in common atom superlattices like $\text{GaAs}/{\text{Al}}_{x}{\text{Ga}}_{1\ensuremath{-}x}\text{As}$, where the antisymmetric contribution to ${G}^{\ensuremath{'}}(z)$ is expected to be small. For superlattices with no common atom, additional interface terms are introduced. If the difference in the spin-orbit splitting energy for the two superlattice materials is comparable with the valence-band offset, then relativistic corrections can introduce many more, weak interface contributions. Part of the relativistic interface matrix has been derived, which includes the most significant terms. Finally, a scheme is proposed for reducing the number of independent Luttinger parameters required, when using the Hamiltonian to fit experimental spectral data.


Objective To understand the situation of urogenital tract mycoplasma infections in married woman of child-bearing age in this area for taking the effective measures to reduce the infection rate.Methods To collect cervical secretions of married women of child-bearing age in the outpatient and inpatient departments of gynecology and obstetrics by asepsis cotton swab according to the asepsis operation and vaccinate in the mycoplasma colored culture for performing the identification and drug sensitivity test.The mycoplasma infection rate and the drug sensitivities were observed.Results Among the specimens in 682 married women of child-bearing age,the urogenital tract mycoplasma infection was in 408 cases with the infection rate of 59.82%,in whichsingle Uu infection was in 297 cases with thepositive rate of 72.79%,but single Mh infection was in 36 cses with the positive rate of 8.82% and Uu and Mh mix infection was in 75 cases with the positive rate of 18.38%.There were statistical difference among various groups.Conclusion Married women of child-bearing age should be strengthened to gynecologica exmamination for achiving early examination,early diagnosis and early treatment to reduce the incidence rate of urogenital tract mycoplasma infection.


To the Editor: I would like to congratulate the authors, Blum J et al., of the article entitled ''Bending and Torsional Stiffness in Cadaver Humeri Fixed with a Self-Locking Expandable or Interlocking Nail System. A Mechanical Study'' (J Orthop Trauma. 2005;19: 535–542), which summarizes a comparative mechanical study performed on 2 different nail concepts. I found this study interesting and informative. However, I do have some reservations regarding factors not mentioned by the authors that may have ultimately affected the final results. They are as follows: 1. Specimen preparation—The authors state, ''Eight pairs (5 from females) of intact, freshly harvested human humeri were used.'' My question is whether the bones were from fresh cadavers or were freshly harvested from a nonfresh cadaver. This point is crucial as a dry bone, after freezing and thawing, may be too fragile for an expandable nail to abut the inner cortex. This study also fails to mention bone geometrical properties in respect to nail diameter. Exclusion of such data might lead the readers to believe that the nail-matching selection process is of minor importance to the torsional results. 2. The tested nail—A. Inserting the nail through a retrograde approach is a little tricky, given the anatomical features of the humerus. The humeral medulla has a funnelshaped configuration, with the larger inner cortex being in the proximal half of the bone (very well illustrated in Fig. 4). Therefore, one must consider that what is sufficient for the expandable nail in the distal part may not necessarily be suitable in the proximal part of the humerus. B. In my opinion, the expandable nail size was incorrectly chosen. It is mandatory to choose a nail that can expand at least 2mm more than the inner cortex of the bone to assure abutment. From Figure 4, we can learn that the chosen nail diameter does not correspond to the bone diameter, and in the proximal part there is almost no contact between the nail and the inner cortex. By a simple observation of Figures 4(A) and (B) and supposing that the UHN is of 7.5mm diameter (worst case), the gap between the nail and the medullary canal of both sides is about 2 to 3mm. In such a case the only Fixion nail suitable is the 8.5mm (8.5 to 13) nail. Both 6.7-mm (6.7 to 10) and 7.4-mm (7.4 to 11) nails are not recommended on the basis of the medullary canal cross section. This mismatch between the nail and bone diameters affects the results and may explain the lower torsional stiffness of the expandable nail.


Death in patietits with coronar>' arlet7 disease frequently is due to sustained monomotphic ventricular tachycardia (VT). which can degenerate to ventricular libriMation.' Because of its infrequenl and unpredictable occurrence, programmed electrical stimulation has long been used to induce sustained VT. whether in the controlled environment of the clinical electrophysiology laboratory for humans or in the research laboratory for infarcted anitnals (such as the dog). In fact, the canine model has been studied extensively because sustained monomorphic VT frequently is inducible early (3 to 7 days) after infarction.-' Mapping studies in this model have detiionstrated epicardial reentrant circuits, suggesting that reentry may be the predominant tiiechanism. A further understanding of the electrophysiologic characteristics of the ventricular tissue comprising these reentrant circuits is critical for developing and refining effective pharmacologic and ablative treatments.


On March 12, 2018, a formal disciplinary complaint was filed in this matter against Montana attorney Brian J. Miller. The disciplinary complaint may be reviewed by any interested person in the office of the Clerk of this Court. The Commission on Practice (Commission) held a hearing on the complaint on April 18 and 19, 2019. Both the Office of Disciplinary Counsel (ODC) and Miller, as represented by their respective counsel, presented argument and questioned witnesses. On July 18, 2019, the Commission submitted to this Court its Findings of Fact, Conclusions of Law, and Recommendation for discipline. Miller then filed objections, and the ODC filed a reply. This Complaint arose from Miller's representation of Plaintiff Billie Redding in Redding v. Prosight Specialty Management Company, Inc., et al., Cause No. CV 12-98-HCCL, before Hon. Charles C. Lovell, Senior United States District Judge for the Helena Division of the United States District Court for the District of Montana. Redding had been previously represented by Montana attorney Linda Deola, a partner in the same firm as Miller. The underlying litigation began in State court, where Deola filed an amended complaint alleging that the defendant insurers acted in bad faith by failing to make a good-faith offer to settle Redding's claims against their insured. The defendants removed the litigation to the U.S. District Court. On February 3, 2014, the U.S. District Court disqualified Deola from serving as trial or deposition counsel for Redding. Miller then entered the litigation, first as defense 11/20/2019


The quest for a consistent theory for quantum gravity is one of the most challenging problems in theoretical high-energy physics. An often-used approach is to describe the gravitational degrees of freedom by the metric tensor or related variables, and finding a way to quantise this. In the canonical tensor model, the gravitational degrees of freedom are encoded in a tensorial quantity $P_{abc}$, and this quantity is subsequently quantised. This makes the quantisation much more straightforward mathematically, but the interpretation of this tensor as a spacetime is less evident. In this work we take a first step towards fully understanding the relationship to spacetime. By considering $P_{abc}$ as the generator of an algebra of functions, we first describe how we can recover the topology and the measure of a compact Riemannian manifold. Using the tensor rank decomposition, we then generalise this principle in order to have a well-defined notion of the topology and geometry for a large class of tensors $P_{abc}$. We provide some examples of the emergence of a topology and measure of both exact and perturbed Riemannian manifolds, and of a purely algebraically-defined space called the semi-local circle.


Q: Nursing's code of ethics is an integral part of our practice standards. What are the must-know principles for nurses? A: To be effective as a profession, nursing requires an accredited education process, a system for licensing and certifi cation, and a code of ethics to guide practice. The American Nurses Association (ANA) Code of Ethics for Nurses with Interpretive Statements helps us maintain professionalism, integrity, and accountability. Initially, nursing ethics outlined what were believed to be desirable virtues or values for nurses in the late 19th century. These early values focused on physician relationships and conduct; however, nursing's code of ethics has evolved to champion patient advocacy.


We compared the changes of soluble sugar,glyceride,free amino acid and soluble protein contents in the 5th instar nymphs and adults of Nilaparvata lugens treated with sub-lethal doses of nitenpyram.The results indicated that the reserves of energy sources in nymphs and adults did have different variation trends.Soluble sugar contents in the 5th instar nymphs treated with LC10,LC30 stress in 12 h and 24 h and adults in 12 h stress were significantly higher than those 0f control;Glyceride contents in 5th instar nymphs and adults treated with LC10 stress were higher than those of control,but under 24 h stress,the glyceride content in the 5th instar nymphs was significantly lower than the control level;The variation trends of soluble protein contents in the 5th instar nymphs and adults were similar to that of free amino acid.The results suggested that under the control of sub-lethal doses of nitenpyram,the 5th instar nymphs and adults may have different coping mechanism and have important significance to understand the mechanism of sub-lethal doses of insecticide inducing resurgence of Nilaparvata lugens.


Once in his Chronicle compiled ca. 1015, Thietmar von Mersenburg names Saint Stephen of Hungary (d. 1038) Vajk. In scholarly literature, the view prevails that king Stephen received this pagan, Turkish by origin, name in his childhood. Contrary to this opinion, it is evident that the name is a literary creation of Thietmar: this bishop often calls foreigners in Slavic (slavonice dictus/dicta) , most probably his native Sorbian. For example, he uses the name Beleknegini for the mother of Stephen, Sarolt, and the name Prokuj, for Stephen's uncle, Gyula. All these Slavic names applied by Thietmar are hapax legomena.


This article argues that, without being reducible to a version of the Free Will Defence, Aquinas´ theodicy and philosophical theology can offer contemporary versions of the Free Will Defence stronger metaphysical and theological foundations from which a response to Mackie´s compatibilistic challenge – probably the most serious challenge against this defence – can be derived. Mackie´s challenge to the Free Will Defence is the argument that the possibility of evil is not a necessary condition for the existence of free will, for God – if He existed and was omnipotent, omnibenevolent and omniscient – could have and would have created rational and free agents such that they would always freely choose the good. I claim, following Aquinas´ hylomorphic ontology, that the creation of such a will is logically impossible as it would require the creation of a will containing naturally and invariably the formality of the universal and perfect good, and so the creation of a will indistinct from God´s, which is by nature uncreated.


ABSTRACT This study aimed to describe the aesthetic values based on the element of unity, harmony, balance, simetry, and opposition in hikayat Khabar Mati that developed in Simpang Kapuak Society, Kecamatan Mungka, Kabupaten 50 Kota. The theory is used to analyze the aesthetic value of the hikayat Khabar Mati are a theory of oral literature and hikayat proposed by Emies and Sharif (Majlis Peperiksaan Malaysia, 2006) and Nurizzati (1994), the theory of aesthetics proposed by Atmazaki (2007) and Ratna (2007). The research is a qualitative study using descriptive methods. The object of this research is a old prose hikayat at Kenagarian Simpang Kapuak, Kecamatan Mungka, Kabupaten 50 Kota.The Focus of hikayat is aesthetic values based on the element of unity, harmony, balance, simetry, and opposition. The technique to collect the data are: (1) to translate raw materials of hikayat in Minangkabau language that has tittle Khabar Mati into Indonesia language, (2) inventory make a note for hikayat data that contain the element of unity, harmony, balance, simetry, and opposision, (3) to agglomerate aesthetic values that has found on hikayat. The technique in analyzing the data are (1) to interpret the aesthetic values that exist in the hikayat, (2) describe the aesthetic values in the hikayat, and (3) draw conclusions. Based on the analysis of data found the aesthetic values of the hikayat Khabar Mati as follow: firstly, there are 77 data about the element of unity as nan manjago said that a unitary form of the word angel of death. Secondly, there are 73 data about harmony, like a sentence pado Ibrahim mouk bakato, wahai Ibrahim saudara ambo , occurred because of interaction reasonable harmony and similarity of views between the first array to the second array. Third, there are 70 data about the balance, such as the array nan cilako mandonga hatinyo godang, tambahan guru sudah mambilang, hiduik ka dipakai mati ka ditumpang, inilah dayo sudahlah datang is the word in the second line there is a word that confirms the first array. Fourth, there are 73 data of symetry namely precision of comparison between poetry and the number of syllables in the couplet by couplet which has nearly the same amount. Fourth, there are 12 data about a opposition like siang and malam in a sentence siang bagolak malam bagurau. The analysis showed that the element of unity is more dominant than the other elements. Based on the results of this study concluded that the hikayat Khabar Mati contain elements of aesthetic values. Keywords: Aesthetic value, Hikayat Khabar Mati, Kenagarian Simpang Kapuak


This paper investigates the problem of polynomial fault detection filter design under an adaptive event-triggered scheme for continuous-time networked polynomial fuzzy model–based (PFMB) systems considering network transmission delays. The proposed adaptive polynomial event-triggered scheme is checked only at the sampling instant to eliminate the Zeno behavior as well as save the network bandwidth. With the consideration of the mismatched membership functions (MFs), the asynchronous problem between the physical plant and the polynomial fault detection filter (PFDF) is examined. A Lyapunov–Krasovskii (L-K) function is introduced to deal with the time delays caused by the network transmission and the zero-order holder (ZOH), and a proper line-integral Lyapunov function is also introduced to reduce the conservation of the design constraints, whose analytical procedure is rule-dependent. The design constraints are given in the form of sum of squares (SOS) to keep the PFMB fault detection system asymptotically stable with H ∞ performance γ . Finally, an inverted pendulum example together with a numerical example is given to verify the effectiveness and superiority of the proposed scheme in terms of transfer rate and conservatism.


The storage hexamers are a family of insect proteins with native molecularweights around 500,000 with six homologous subunits weighing generallybetween 70,000 and 85,000 daltons. They are synthesized and secreted by thefat body of feeding larvae and nymphs and reach extraordinary concentrationsin the hemolymph just prior to metamorphosis. In holometabolous insects,they are partially recaptured by the fat body during the larval to pupal moltand stored in cytoplasmic protein granules, as well as in the hemolymph of thepupa. They disappear from these reservoirs during adult development; inmany insects, both hemi- and holometabolous, they are also utilized duringthe nymphal or larval molts. Their amino acids are primarily incorporated intonew tissues and proteins during adult development, but they may also beincorporated into cuticle as intact protein, and in one case were found to bediverted to a small degree into energy metabolism. Finally, some storagehexamers have ligand binding and transport capabilities. Functionally, de-velopmentally, and evolutionarily, they are a complex family of proteinswhose analysis promises to be exceedingly useful in the study of many basicproblems in the biology of insects.2050066-4170/91/0101-0205 $02.00Annual Reviews www.annualreviews.org/aronline


We solved with a numerical procedure the HTL improved ladder DS equation for the retarded fermion self-energy function $\Sigma_R$ to study the spontaneous generation of fermion mass in thermal QCD/QED, and studied the gauge-dependence of the solution within a general covariant gauge where the gauge parameter $\xi$ is any constant number.
With the numerical solutions thus obtained, we found the followings; i) The fermion wave function renormalization function $A(P)$ always deviates largely from unity even at the momentum where the mass is defined, thus the corresponding solutions explicitly contradict with the Ward-Takahashi identity. ii) As a result, the obtained solutions strongly depend on the choice of gauge parameters: the critical temperatures and the critical coupling constants significantly change gauge by gauge. In all gauges we studied in the present analysis, we could not find any solution, having a possibility to be consistent with the Ward-Takahashi identity. Thus we are forced to investigate the procedure to find a gauge which enables us to get a solution being consistent with the Ward-Takahashi identity, otherwise we can not obtain any physically sensible conclusions through the analysis of the point-vertex ladder DS equation no matter how the gauge propagator gets improved.


Manual cattle handling systems are widely used in South Africa. A literature review and consultations were conducted to assess the advantages and disadvantages of various cattle handling systems with the objective of developing a more efficient system that incorporates automation, electronics and Radio Frequency Identification (RFID) technology. This document describes the research and development process which included planning, literature review, consultation, design, fabrication, evaluation and discussions. In this study an automated, selective sorting (RFID) based cattle handling system was developed and assessed as an alternative to the widely adopted conventional manual management system practiced in South African. The RFID based system developed consisted of manual, semiand fully automated components in the form of a neck-body clamp with through access, flow control double split gates and a weigh-identification-sort system. For the ease of comparison the system was developed with a manual by-pass as a control to compare the automated and manual systems in terms of establishment cost, handling duration including identification, weighing and sorting, and operator and animal stress levels which impacts on business profitability and system efficiency. The system was evaluated for both the manual by-pass and RFID automation incorporated states. Infrastructure improvement resulted in reduced handling duration, operational costs and handling stress on both operator and the animal whilst enabling selective automated sorting. After incorporating RFID, electronics and automation on the same system, it was established that, on average, cattle handling duration was reduced by 63%, incorrect sorting was reduced by 5.5%, man hours were reduced by 70%, with 23% and 14% less fatigue and stress levels, both to the handler and the animal respectively, whilst achieving efficient selective sorting. The infrastructure was designed for 500 animal per day capacity, 5 men handler at a capital investment of R 200 000 and an operational cost of R25 000/month. Although there is still need to further investigate the performance parameters under different environments, it can be concluded that the introduction of RFID, electronics and automation improves the overall system technical efficiency by 32% whilst enabling efficient selective handling.


Minutiae-based fingerprint recognition is a challenging problem, mostly due poor quality of the sensing image, large nonlinear distortion among dissimilar impressions of similar fingerprint and several common transactions. Those problems make poor feature extraction and matching. Most of the fingerprint matching system is constructed on minutiae-based feature vector. The minutiae position, size and direction of the fingerprint impression must be invariant to scaling and rotation. Such distortion problems are generated by the image capturing devices; in this study the scanned fingerprint image is subjected to feature extraction and minutiae evaluation. In the feature extracting stage image pre-processing, minutiae extraction is accomplished and in the minutiae evaluation stage the original minutiae was evaluated. The scope of this work is to attain invariance by extracting the characteristics based on the spatial connection between minutiae points. We suggest four minutiae based structural local feature vectors, at the same time it is expected to fulfill at least two necessary feature vector properties. These feature vector descriptions support in solving the spurious and missing minutiae problems and hence help us develop a robust person authentication system. The performance improvement of the proposed system is evaluated by Goodness of Index (GI) GI values. These techniques achieve effectiveness with the help of FVC databases.


Highly isotactic poly(2-vinylpyridine) (P2VP) was synthesized by the group transfer polymerization of the prochiral 2-vinylpyridine (2VP) with 2-methoxyethylaminobis(phenolate)yttrium complexes. Isotacticities of up to Pm = 0.92, narrow molecular weight distributions, and high molecular weights were achieved by steric modifications of the variable bisphenolate ligand structure. The resulting polymer samples were characterized by thermoanalysis (DSC, TGA), GPC, and 13C NMR. The origin of the isotactic microstructure was attributed to an enantiomorphic site control mechanism based on 13C NMR mechanistic studies and allowed new insights into 13C pentad assignments.


Objective: The purpose of this study was to determine the expression of miRNA-92A in Bladder Cancer can be used as a marker of tumor. Material & Methods: This study used a total of 30 samples. 15 samples of non-invasive bladder cancer and 15 samples of muscle invasive bladder cancer. The sample was obtained in the Anatomical Pathology laboratory from January 2016 to December 2016. Tumor tissue then extracted miRNA-92A with a RT-PCR examination with Total miRNA Mini Kit FavorPrepTM. The result is done by Mann Whitney U test. Results: The mean expression of miRNA-92A in non-muscle invasive bladder cancer is 12.75 while in muscle invasive bladder cancer had an average value of 31.79. The Mann Whitney U test was used to evaluate the median difference between these groups. There was a significant difference in the expression of miRNA-92A in both groups with P = 0.000 (<0.005). Conclusion: There is a significant difference between the expression of miRNA-92A in non-muscle invasive bladder cancer compared to muscle invasive bladder cancer with more dominant expression on muscle invasive bladder cancer.


Aerial back sonar for use in a car detects obstacles by the echo pulses reflected from the targets. In order to develop highperformance aerial back sonar, we analyzed waveforms of the received pulses using the finitedifference time-domain (FDTD) method [1]. Since back sonar is generally used outdoors, the change of climate may have a significant effect on the received pulses from the objects. The FDTD method calculates the received waveforms from the object as a function of the object's height as temperature and relative humidity in the air change. The result showed that the maximum amplitude of a received pulse had a variation of about 25 % with changing relative humidity. The variation of amplitudes also increased with the variation of temperature. If the amplitude of the second pulse is adapted to the threshold of an alarm, we need to consider the variation of relative humidity and temperature. Introduction The FDTD method calculates the received waveforms from the object as a function of the object's height as temperature and relative humidity in the air change. It is expected the speed of sound is independent of relative humidity at a constant temperature. However, the absorption coefficient should be greatly affected by relative humidity. It is reported that the sound attenuation coefficient of intensity depends on relative humidity. It is calculated the influence of relative humidity when back sonar placed 0.5 m above the ground projects a Gaussian sound pulse of 40 kHz. The object is placed at x = 1.0 m and the ground is rigid. FDTD calculation method The basic equations of the FDTD method, which is taking account of attenuation, are given as follows: 2 1 y x v p v c t x y ρ ∂ ∂ ∂ − = + ∂ ∂ ∂ (1) x x v p v t x ρ η ∂ ∂ − = + ∂ ∂ (2)


The æther of plants appears to be almost destitute of all gross air, from placing it under the receiver of the air-pump; for exhaust the air ever so accurately, this. ætherial liquor remains unmoved, nor does it emit any air-bubbles which immediately arise in other liquors, and according as their quantity of intrinsick air is greater, so much the sooner are such liquors put into agitation, and emit also more froth, and more vehement ebullitions in proportion to viscidity.


The present study was conducted to evaluate the effect of dietary supplementation of clove, peppermint, cinnamon oils and their blends on growth performance, some blood biochemical constituents, antioxidants activities and economic efficiency. A total of 300unsexed (Ross – 308) broiler chicks, oneday old were fed from 1-35days on this specific dietary supplementation. Birds were divided randomly into five dietary treatment groups composed of 60 chicks per group, each in 3 replicates. The 1 group (control) received basal diet without additions, the 2, 3 and 4 groups received basal diet supplemented with clove, peppermint and cinnamon oils at0.3 g/kg diet of each, respectively and, the 5group received basal diet supplemented with blend of clove, peppermint and cinnamon oils at 0.1 g/kg diet of each. The results indicated that essential oils blend dietary supplementation significantly improved body weight, gain, feed conversion ratio, performance index in different periods of the experiment. Dressing, giblets and some immune organ percentages had higher values in the essential oil supplemented chicks than the control, while abdominal fat percentage had lower values in the essential oil supplemented chicks than the control .Broiler chicks fed the essential oil diet had greater serum total protein, glutathione (GPx) activities and high density lipoprotein (HDL)than those fed the control, however, significantly decreased serum cholesterol, triglycerides, low density lipoprotein (LDL) and lipid peroxidation (MDA) concentrations. In conclusion, beneficial effects of using blends of clove, peppermint and cinnamon oils at 0.1 g/ kg diet had been obtained on performance, blood biochemical and economical efficiency with no harm effect on health under experimental conditions.


Background: Despite the wide use of motor evoked potential(MEP) monitoring in spinal deformity surgery in recent years,its different alarm criteria and related response protocols used in different studies compromise their comparability. Furthermore, high false positive rate of MEP reported by previous studies has become an increasingly prominent problem which will limit its clinical use and development.Objective: The aim of our study is to develop and evaluate a protocol of intraoperative MEP monitoring based on our clinical experiences and the review of previous literatures.Methods: The data of MEP monitoring of 1543 consecutive patients who underwent spinal deformity surgeries between January 2010 and December 2014 were retrospectively analyzed. Age, gender, diagnosis, operative time, intraoperative MEP change and postoperative neurologic status were collected. The protocol with the warning criteria we had established was used. The false positive rate, false negative rate, sensitivity, specificity and positive predictive value were calculated.Results: Significant intraoperative MEP changes were found in 85 patients(5.5%). In 41 of them, significant MEP changes were synchronously and logically associated with high-risk surgical maneuver(pedicle screw insertion, osteotomy, correction, etc), and thus considered as alerts. There were a total of 28 true-positive cases, 5 false-positive cases, and 8 indeterminate cases. The false-positive rate of MEP monitoring was 0.33%(5/1502); whereas the sensitivity and specificity of MEP for detection of intraoperative spinal cord injury were 100% and 99.6%, respectively. The positive predictive value of a MEP alert in terms of a new postoperative neurologic deficit was 84.4%.Conclusions: Our study indicates that the appropriate use of MEP monitoring based on our protocol is able to obtain satisfying sensitivity and specificity and thus provide important information for intraoperative decision-making.


Nippon Steel is exerting efforts to open up new applications for titanium, such as its uses as a material for buildings, civil engineering and ships, and other marine structures. In the building materials field, the company has realized various surface finishes to meet the diverse needs of its customers. In the civil engineering area, it has developed techniques for lining structures with titanium-clad steel sheets. Recently, the company has applied titanium to the pontoons of a floating bridge linking Yumeshima and Maishima Islands in the Port of Osaka. In other marine applications, Nippon Steel has produced all-titanium ships, spurring interest in the wider use of titanium in shipbuilding.


Combined effects of Cr content and pH on corrosion rate of carbon steels due to flow accelerated corrosion have been examined by experiments and their relation to oxide scale characteristics based on detailed oxide layer characterizations using transmission electron microscope with X-ray analyzer have been discussed. Effect of Cr content on FAC mitigation decrease continuously as pH is increased from neutral to 10.4 and effect of pH on that increase significantly from pH 9.1 to 9.4. Obvious Cr enrichment has been observed in the oxide layer of 1.01 wt% Cr content steel regardless pH condition. Cr concentration is highest at top surface of oxide layer, and that decrease from surface to oxide / metal interface gradually. It has been suggested that Cr enrichment stabilize oxide layer (decrease solubility and defect density of oxide layer), as a result, FAC suppressed.Copyright © 2010 by ASME


Parks have an important role for residents of the city of Surabaya, in addition to functioning as a place of relaxation, parks also have various important roles such as as a source of city lungs, family recreation facilities, entertainment, health, and sports to sharing knowledge and culture. Park Bench is one of the important facility products that can increase the value of satisfaction in the minds of visitors. The research here tries to explore further the design of the park bench by looking at the suitability of various aspects to support the comfort and safety of its use.          In this study, trying to harmonize the design of park benches by developing the concept of comfort and safety on ergonomic standards, first, the researchers studied and analyzed the existing conditions of several parks in the city of Surabaya and also analyzed the sources of supporting literature. Existing in this study took several samples of city park benches that matched the criteria to be used as subjects in the study, the two researchers then analyzed the criteria for developing product design management by looking at the needs of the user aspects by combining them with the suitability of Ergonomics standards. Furthermore, the researchers also tried to look at other supporting attributes in supporting the level of comfort and safety of park benches such as product quality consisting of aesthetics and functionality. The three researchers carried out data processing and calculations for calculating ergonomic values that could be applied to product design.         The research here is expected to be able to understand more deeply related to the development of the Surabaya city park bench design by applying the comfort and safety attributes in more detail and also to understand the standard characteristics that can be applied to the next park bench product design.


This article focuses on the research of colour as applied to N. Medtner's piano works. It discusses the composer's views on brilliance of colour, "sonority" (звучность) of music and texture as one of its most important means of expression. It is proved that colour interpretation of piano music texture in Medtner's works differs from the views on the colour embodied in the impressionists' music. Thus, that formed an opinion about "scarce colours", colour insufficiency of Medtner's musical compositions. Basing on the analysis of Medtner's works, the author changes the existing point of view by showing the dependence of specific colour of Medtner's works' texture on this original composer's rich, artistic and figurative system of music, thus actualizing the need for in-depth research of semantic contexts of his artistic images for the formation of the tradition of Medtner's music performance..


We ask why value has not migrated in the automobile sector, despite expectations that it would follow the example of computers. We explain the factors underpinning stability in terms of value distribution in this ecosystem. Automobiles underwent vertical disintegration yet, unlike computers, the sector remained hierarchically controlled. Due to greater market scale and slower growth, plus persistence of integral product architecture, industry standards failed to emerge. Slow clockspeed, user requirement stability, and downstream access lock-in, as well as legal liability and certification, all acted as forces of stasis. We illustrate how these structural features interact with strategic agency of OEMs, intent on maintaining their central role as system integrators: retaining dominant influence over the locus of differentiability along the value chain and managing relative replaceability.


The present publication discloses a method and system for sending messages in a telecommunications network (1, 2, 6, 11, 12), in which method digital messages (40) which contain information on the desired reply address (32) are mass sent (3), and messages, which are sent on the basis of the reply-address information (32) are received (10). According to the invention, the reply-address informationof each mass-sent message (40) is converted (3) to correspond to a predefined dialogue, in which the stage of the dialogue defines unequivocally the reply-address information (32), so that the transmission and reception of the messages are implemented in different parts of the telecommunications system (1, 2, 6, 11, 12).


The laser cladding metal based titanium carbide research present status and application development were introduced.The research progress from three respects separately: direct cladding titanium carbide,synthesis titanium carbide reinforcing phase,rare earth's modification on titanium carbide reinforced phase was introduced.From the physical and chemical properties of titanium carbide,the effects of cladding methods,cladding powders and substrates on the microstructure and properties of the cladding layer were introduced.


To determine if the different EEG patterns noted in previous studies were due to between-task differences in muscular exertion, the present study examined the electroencephalographic (EEG) activity in the seconds prior to either holding the weight (without lifting) or executing an arm lift at either 25% or 95% of the subject's one-repetition maximum value. Temporal EEG and tempomandibular and trapezius electromyography (EMG) measures were obtained from subjects (N=20) in the half-second period during the holding of the weight or immediately before lifting the weight. The degree of attentional focus on the task was quantified through self-report measures after each set of trials. EMG activity was not significantly different between the hold and lift phases. The self-report degree of attentional focus was higher in the lift phase, compared to the hold phase, for both 25% and 95% conditions (p<.01). Increases in EEG activity for the 25% condition were observed between the hold and lift phases at 4 Hz (p<.003...


In order to obtain the comprehensive characteristics of main embankment of Yangtse Rive in southern Jingzhou Zone of China,considering solid-liquid two phases behavior of the embankment,and based on the analytic hierarchy process and the fuzzy consistency theorem,a fuzzy comprehensive judgement system model was constructed.With normal fuzzy membership function and two weighted theories,embankment construction safety comprehensive judgement was realized.Based on the conclusion of fuzzy comprehensive judgement and combining with indirect method of model discrimination,generalized multi-dimensional weighted fuzzy discriminating model was set up.Furthermore,typical embankment section safety model discrimination was implemented and sensitivity analysis of the model system was carried out.Engineering philosophies founded here comprehensively reflects the safety characteristics of the main embankment under complicated engineering background,and is applicable to direct embankment system management and monitoring on site.


In search of energy storage solutions, polymer electrolytes are particularly interesting due to their high intrinsic safety. We show for the first time a lithium metal polymer battery working with a polymer electrolyte based on poly(lactic acid) exhibiting a remarkably low charge transfer resistance. This polymer is produced from lactic acid, which can be obtained from trashes and renewable sources. Thus, a significant fraction of fossil raw materials could be eliminated from the production of the battery components. By incorporation of the ionic liquid N-butyl-N-methylpyrrolidinium bis(trifluoromethane-sulfonyl) imide (Pyr14TFSI), fully amorphous, solvent-free, very low-volatile solid polymer electrolytes (SPEs) are obtained which are shown to be thermally and electrochemically stable electrolytes in lithium metal polymer batteries. A lithium metal polymer battery with a composite LFP cathode was successfully cycled with this electrolyte showing its potential for applications. We conclude that alternatives to the benchmark PEO, like ionic liquid plasticized polyester, are worthy of paying attention because of the low charge transfer resistance with lithium metal.


The aim of the present study is to demonstrate that research focusing merely on economic and physical effects in a given area, and ignoring the social aspects and ambiance of new transport infrastructure, inevitably suffers a loss of quality. The special characteristic of the present study lies in the way in which it assesses infrastructure developments, in regions that were previously peripheral, on the basis of urban development phenomena, social phenomena and ambiances.


Landscape is a recurring subject in the geographical literature and one which has been subject to analysis from a variety of different perspectives. Rural landscapes, in particular, usually account for a full chapter in most rural geography textbooks. Rural landscape is an ecological construction as well as an historical and cultural one, a heritage of the past as well as the result of new dynamics. While exhibiting great diversity, rural landscapes can nevertheless be divided into a number of main types. Many factors contribute to this diversity, from production objectives to land tenure regimes, inheritance regimes, productive structures, logics and strategies and the degree and characteristics of market participation. The focus of this paper is on agricultural and agritrade policies as engines of landscape transformation at the national, international and global levels. Rural policies are also considered in the case of some OECD countries and the European Union in particular. Finally, the foreseeable consequences of the Eastern enlargement of the EU upon the dynamics of creation and transformation of agrarian and rural landscapes is analysed, with special emphasis on the Portuguese case.


ABSTRACT This paper adopts the concept of a moral economy as a lens through which to analyze the neoliberalisation processes that have transformed the field of higher education in recent decades. Specifically, I consider a case study of the commodification of a senior citizen course-auditing program at an Israeli university in the early 2000s. The program, which was initiated in the late 1970s, began as a free public service to the elderly population, yet was later redefined and remodelled as a profitable economic activity. Drawing on extensive archival research, I focus on the debate between the decision's opponents and its supporters, who represent, respectively, the traditional moral economy of the university on the one hand, and emerging market-oriented values on the other. In particular, I illuminate changes in university managers' practices and perceptions regarding the public roles and societal obligations of public higher education institutions.


NMR spectroscopy in liquid crystal solutions of polypeptides has been used for almost two decades, and has been shown to be a useful technique for the structure determination and the chiral discrimination of organic solutes. However the underlying mechanism remains largely unknown and there are several open questions. They concern the nature of the forces which control the anisotropic distribution of solutes: are there specific interactions, like hydrogen bonds, which involve selected chemical groups? Also the effects of co-solvent and temperature are scarcely understood: do they control the polypeptide-solute interactions or do they play an indirect role, by affecting the structure of the polypeptide? The lack of knowledge is a limit for the full exploitation of the NMR technique in liquid crystals. A deeper insight would be important to guide the optimization of the working conditions, e.g. by a proper selection of the polypeptide/co-solvent pair, given the nature of the solute. Especially challenging is the phenomenon of chiral discrimination. It occurs because pairs of enantiomers interacting with chiral polypeptides form diastereoisomeric pairs, but the forces relevant to this purpose are not known.
In this thesis the behaviour of solutes in ordered solutions of poly(γ-benzyl-glutamate) (PBG) has been investigated using computational methods. The theoretical work has been carried out in close connection with experimentalists, from the laboratory of the Laboratoire de RMN en Milieu Oriente, Institut de Chimie Moleculaire d'Orsay de l'Universite de Paris Sud, 11 (ICMMO) where a peculiar expertise in NMR techniques in liquid crystal media has been developed. Theoretical results have been checked against NMR data; moreover, new measurements have been performed in parallel with the computational study, to control the consistency of theoretical and experimental results. A major objective of this thesis has been the development of new computational tools for the analysis of experimental data, with the two-fold purpose of (i) helping the spectral interpretation and (ii) extracting the structural information which is contained in experimental data. In this thesis we have explicitly considered natural abundance deuterium (NAD) 2D-NMR experiments, so we have focussed on 2H-quadrupolar splittings; however the methods used here could be extended to other kinds of magnetic interactions.
We have used different approaches to address the problems of chiral discrimination and structure determination. Chiral discrimination has been studied by fully atomistic Molecular Dynamics (MD) simulations. This level is needed, since the difference of orientational order, and then the spectral differences, between enantiomers is extremely small and depends on details of the intermolecular potentials. This is a general feature of chiral properties, which result from a subtle balance of energetically comparable contributions. This study had first of all an explorative purpose: it had to be assessed whether methods based on empirical intermolecular potentials could provide reliable information on chiral properties. A few solutes were investigated, but most of the work focussed on the prochiral molecule benzyl alcohol (BZA), which was found to be particularly appropriate for two main reasons. First, it exhibits a large difference in the 2H quadrupolar splittings of the two enantiotopic directions; moreover, it can be used as co-solvent, and this can be to improve the sampling efficiency in MD simulations.
The problem of structural analysis is comparably less delicate, because the experimental differences in orientational order between molecules with different chemical structure are relatively larger. From the theoretical point of view, this means that approximate models can be developed, which are useful to rationalize the mechanism of solute ordering. Moreover, the availability of less demanding approaches, able to provide reliable predictions of order parameters, and then patterns of 2H-NMR splittings, at a relatively low computational cost, is essential for the development of computational tools to be used in connection with experiments.
The thesis is divided in two parts. The first part is dedicated to the problem of structure analysis. In chapter 3 the so called tube model will be presented, for the calculation of the deuterium quadrupolar splittings of a solute on the basis of its chemical structure, under the assumption of simple steric repulsions with the polypeptide. The subsequent chapter 4 illustrates the computational methodologies which have been developed to predict the deuterium quadrupolar splitting profiles for flexible solutes, using the tube model coupled with suitable sampling of molecular conformations. Chapter 5 reports the experimental and theoretical study of a series of saturated fatty acid methyl esters (C14 –18). Chapter 6 presents a systematic study of saturated, unsaturated and conjugated fatty acid methyl esters and shows how torsional parameters can be extracted from the 2H quadrupolar splitting profiles.
The second part of the thesis deals with chiral discrimination. In chapter 7 the results of a series of NAD 2D-NMR experiments on BZA, carried out at the ICMMO will be summarized. Then, chapter 8 is dedicated to Molecular Dynamics simulations. First the preliminary study of PBLG in chloroform will be presented, which was used to validate the parameterization of the force field for this polypeptide. Then, the results obtained for BZA in binary and ternary mixtures will be reported.


[Objective] The study aimed to acquire the NBS-type resistance gene analogues in wheat TcLr24.[Method] Degenerate primers based on conserved motif(P-loop and GLPL)of the nucleotide binding site(NBS) region from the cloned plant disease resistance genes were used to isolate resistance gene analogues(RGAs) from genomic DNA of wheat TcLr24.[Result] 13 RGAs with uninterrupted open reading frames(ORFs) were obtained The analysis of RGAs amino acid sequence structures suggested that they contained the domains such as P-loop,Kinase-2,Kinase-3a,and GLPL,while the 13 RGAs deduced amino acid sequences showed identity ranged from 36.1% to 98.3%.Cluster analysis showed that 13 RGAs and RPS2 and Xa1 were clustered into one group.[Conclusion]Results showed that NBS type RGAs isolated from wheat TcLr24 might have different mechanism from Lr21.


The paper presents analytical data generalization of modern methods of natural and waste water demanganization. Reagent, biochemical, membrane, sorption and electrochemical methods of cleaning have been considered.


An outbreak of ulcerative stomatitis was observed in a donkey (Equus asinus) dairy herd. Similar lesions were also observed on the dams' udders and, sporadically, in genital areas. The lesions typically resolved in 1–3 weeks. An α-herpesvirus, Varicellovirus, genetically related to equid herpesvirus type 3, was identified.


Objective To explore operation methods of zygomatic-orbital- maxillary bone fracture.Methods 28 cases with this fracture we re treated with coronary incision an d incision under eyelid or orbit,and rigid inner fixation with mini titanium pla te were made.Results The results of 26 cases were excellent.F unctional paralysi s of temporal branch of facial nerve was observed in 5 cases,but the symptom was disappeared after two weeks.Conclusion This method of treatm ent is useful.


Any study seeking to examine the National Police Reserve (NPR) in detail must first look at the literature which already exists on the force. This chapter begins with an examination of this material, looking at the range of English and Japanese language scholarship which exists on the NPR. The relative strengths and weaknesses of this material are examined, as are its interpretations of the character, creation and evolution of the NPR. The chapter also examines the various archival materials available on the NPR and looks at the relative merits and shortcomings of them when used to analyse the force. It concludes with an exploration of some of the contested concepts surrounding the NPR and offers a set of definitions from which a more nuanced analysis of the NPR can be drawn. The English language scholarship on the NPR exists across a chronological and ideological spectrum.Keywords: English language scholarship; Japanese language scholarship; National Police Reserve (NPR)


In a microarray biosensor, the surface characteristic for reducing background nonspecific binding is a critical aspect for achieving the high sensitivity and accurate detection. In this paper, we proposed a new high-intensity and reduced nonspecific binding microarray fabrication method with a selective dewetting process on a mixed self-assembled monolayer (SAM), consisting of methyl-terminated and methoxy-[poly(ethylene glycol) (PEG)]-terminated silanes. The combination of hydrophobic and hydrophilic properties of the mixed SAM background layer provided the hydrophobicity that allowed the selective dewetting of the protein solution at specific versus nonspecific regions and reduced the nonspecific binding owing to hydrated PEG chains in the mixed SAM. The wiping process was applied for obtaining high throughput and reducing protein usage. Finally, the background non-specific binding was significantly reduced by 78% with a selective dewetting method compared with the standard method using a cover slip. Furthermore, the peak intensity was increased by 20% and the protein usage was reduced versus the standard method.


In this thesis existing theory is extended by combining work engagement and flow research to generate the concept of task engagement, which focuses on episodes of peak performance at work. Using a critical incident methodology in Study 1, task engagement was found to have three key characteristics (i.e., distortion of time; complete absorption in the task; and is a state of high cognitive efficiency). Both situational (i.e., high challenge/high skills, control, and proximal feedback) and psychological antecedents (i.e., safety, availability, meaning and self-efficacy) were also identified. In Study 2, a longitudinal diary study, study 1 findings were replicated and extended by examining duration and frequency of task engagement episodes at work, and their positive impact on employee well-being. Overall, task engagement was found to be a temporal and dynamic construct, involving the interplay of person and situation, which has implications for employee task performance and well-being.


The purpose of the case study is to use 5S tool to assist small scale manufacturing organization to become more productive and more efficient. A simple approach has been adopted to create the teams for implementing 5S. In the frames of case study, it has been analyzed that implementation of '5S' resulted in overall improvement of the organization. With the implementation of '5S', major benefits in the form of tools searching time has been achieved. Tool searching time from shop floor has been reduced from 40 minutes to 5 minutes. '5S' audit has been conducted in the organization. '5S' audit score has been increased from 7 (week 1) to 56 (week 16). 5S is powerful tool and can be implemented in various industries whether it's micro, small, medium or large. Implementation of 5S has large horizontal development and can be implemented in all the workstations of the organization. The publications and case study presented in this paper will be useful to researchers, professionals and others concerned with this subject to understand the significance of 5S.


This paper is devoted to issues in the development of modern-day Russian architectural theory. It considers a number of significant theoretical concepts put forward by representatives of the Russian architectural school. The paper consists of three essays: «From Avant-Garde to Rearguard. Historical lessons from 20 century Russian architecture», «Image and Morphology. From the Perceiving Individual to the Interpreting Individual», «From Architecture of Static Volumes to Variable Multilayered Environments» which present the author's view of the sources of and possible prospects for theory of architecture in Russia.


Polyphenoloxidase( PPO) and peroxidase( POD) are important for plant resistance and can be induced by elicitors.In this paper,three elicitors( Salicylic Acid,Chitosan oligosaccharide and Methy jasmonate) with different concentrations were sprayed on the seedlings of ramie ″Chuanzhu No.8″,and then PPO and POD activities at different time were monitored.The elicitor with a certain concentration which could stimulate the highest increase of enzyme activities was regarded as the suitable one.The results showed that these three elicitors could all raise enzyme activities of PPO and POD.Especially 0.8mM Salicylic Acid,3g / L Chitosan oligosaccharide and 1mM Methy jasmonate could induce higher enzyme activities than other concentrations of the same elicitors.Additionally,the peak of both the enzyme activities appeared around 7-8d after spraying 0.8mM Salicylic Acid,and the effects were more stable than the other two elicitors.Therefore,Salicylic Acid was selected as a better elicitor for inducing ramie resistance,0.8 mM of concentration and spraying 7d early could get a good result.


7251 Background: Topotecan has a role in the second-line therapy of small cell lung cancer (SCLC), and has activity in advanced non-small cell lung cancer (NSCLC). The objective of this study was to determine the safety and maximum tolerated dose (MTD) of a novel combined chemotherapy regimen: topotecan (T), doxorubicin [Adriamycin (A)], and vincristine (V), for the development of Phase II trial.

METHODS
Patients (pts) with advanced SCLC or NSCLC who had incurable disease were enrolled.Pts should have failed palliative chemotherapy first, unless they have extensive disease (ED). The schema used for therapy was: T was escalated from 0.75 mg/m2 days 1-5 every four weeks; fixed doses of V and A were given at 1 mg/m2 days 1 and 5, and 30 mg/m2 day five only, respectively. Each cohort had three pts. Dose limiting toxicity (DLT) was defined as grade 4 hematological toxicity persisting for more than 7 days or any grade 4 non-hematological toxicity.

RESULTS
Fifteen pts were enrolled: 8 males and 7 females, with a median age of 53 years (35-72 years). Thirteen pts were white, and 11 had a Hispanic origin. Nine pts had NSCLC and six SCLC. A total of 36 cycles of TAV were given. The combination was well tolerated. No DLT were seen in the 0.75 mg/m2 or 1 mg/m2 cohorts. Only 1/6 pts developed DLT in the 1.25 mg/m2 cohort with grade 4 neutropenia and thrombocytopenia. We stopped accrual in the 1.5 mg/m2 cohort; we did not consider necessary to increase the dose of T because this is the dose commonly used as a single agent. From the 9 pts with NSCLC: all were stage IV, 4/9 had received at least 2 lines of palliative chemotherapy, 4/9 had failed radiation, and 1/9 pt had a sustained PR (11%). Among the 6 pts with SCLC: 5 had ED (3 already treated with chemotherapy), and one with limited disease that had relapsed. The overall response rate was 2/6 (33.3%): 1 CR and 1 PR, with another patient who attained SD (16.7%).

CONCLUSIONS
The MTD for T is close to 1.25 mg/m2 for this combination based on our experience and the data in the literature. The activity seen in ED-SCLC (50% clinical benefit) may justify the development of a Phase II trial in this setting. [Table: see text].


This research is aimed to the practice of music group therapy to reduce anger for elderly in a government nursing home. Anger can be defined as a psychobiological emotional state or condition that consists of feelings that vary in intensity from mild irritation or annoyance to intense fury and rage, accompanied by activation and of neuroendocrine processes and arousal of the autonomic nervous system. While music therapy is the clinical and evidence-based use of music interventions to accomplish individualized goals within a therapeutic relationship. The research use pre-test post-test one group design. Beside using the interview method, pre-test and post-test also been involved to measure the anger intensity of the participants against anger before and after the intervention. There are three participants. The result showed that music group therapy could reduce the anger of the elderly living in government nursing home.


part of the nineteenth century, been the focus of numerous studies both by foreign and local scholars (for example Abd. Rahrnan Haji Mohamad [1964], de Josselin de Jong [1951], de Maubray [1931], Hooker [1969] and Nordin Selat [1976]). These studies deal with almost every aspect of the system. From the vast amount of materials two general conclusions can be * Jabatan Sains Kemasyarakatan, Fakulti Pengajian Pendidikan, Universiti Pertanian Malaysla, Serdang, Selangor, Malaysia 1) ln some parts of Negeri Sembilan, espeeiany in the district of Port Dickson, the Adat Perpatih is not practised. However, there are groups of people eutside Negeri Sembilan, such as in Naning, Melaka and in enclaves in Lukut in Kota Tinggi, Johore, practising the adat. Leadership


According to the properties of Morrey spaces,the boundedness of the commutators for Marcinkiewicz integrals is studied.It is proved that the commutators of Marcinkiewicz integral μb has the (μpq(ν),BMO(ν))-boundedness.


The programming process of full text retrieval design exploiting Lucene and Tika is introduced. Tika is used for get Metadata and extract text from documents. The index creating and retrieval service is realized by Lucene, we analyze the specific characteristics of Lucene API. Web access processing of search service is implemented using Spring MVC. The service can provide uniform retrieval service for documents in forms of HTML, PDF, WORD, PPT, mht and so on in web sites. Personalized content retrieval service system can be created based on this paper.


This paper consults and improves the on hand computational methods and circuits, which comprehensively utilizes the knowledge of the Aerodynamics, the heat transfer theory, the radio optics, ANSYS and so on. In the analysis of the IR characteristics of aerial targets, taking it into account that most of the computing methods on hand are empirical or semi-empirical, which are more simple, but more limited, less sufficient and scientific and have more human factors, so we begin with the determination of the thermal field, adopt the numerical method to realize the calculation and modeling of the IR radiation with ANSYS, analysis how the spectral coverage and the observed bearing affect the IR radiation, and then get the credible and all-side numerical calculation results. Then, this paper introduces a method utilizing 3DS MAX and OpenGL to generate the IR picture of the target, which divides the grey level of the IR radiation reasonably according to the final numeric calculating results and the principle of the grey level division, and then we generate the IR pictures of the aerial targets.


An iris-loaded circular waveguide 1.3 m long, operating in the low-loss circular TE01 mode, produced 500 ns differential delay for a 50 MHz bandwidth at X band. The insertion loss was 2.2 dB.


This essay describes instances in the rhythmic play with affect in the reading of and performances with Kathleen Stewart9s Ordinary Affects. It offers an engagement with the work that both troubles and is troubled. It celebrates this engagement and delights in the opportunity to read, read around, and read again and again words that flee from identification and representation and come to life in moments of tears, smiles, and writings living in the temptation and allure of the unknown. This was written with a visit to Edinburgh in mind and Robert Frank9s The Americans, alongside Stewart9s Ordinary Affects in my shoulder bag.


Ferrocement is a highly versatile construction material and possess high performance characteristic, especially in cracking, strength, ductility, and impact resistance as its reinforcement is uniformly distributed in the longitudinal and transverse directions and closely spaced through the thickness of the section.. There is an ample scope for mass production and standardization together with the economy in construction. Ferrocement is suitable for low-cost roofing, pre-cast units and man-hole covers. It is also used for the construction of domes, water tanks, boats, silos and folded plates. An experimental investigation on flexural behavior of trough shaped ferrocement panels reinforced with skeletal steel and GI hexagonal wire mesh with varying number of wire mesh layers is presented. The slab panels are tested under flexural loading by applying line loads at 1/3rd points. From the studies, it is observed that the load carrying capacity, deformation of ultimate load and energy dissipation capacity are high in case of increasing number of wire mesh layers. Further it is observed that a reduction in crack width and increase in no of cracks indicates the delay in crack growth.


The integration of modern information and communication technologies (ICTs) within the cultural domain creates what is commonly known as e-culture. The need to create an e-culture environment arose from the undeniable fact that the cultural heritage of a nation defines it and, therefore, should be disseminated to all, regardless of their location and their disability. This article discusses an e-culture portal, which presents to any interested users, information regarding a significant number of Greek and Cypriot museums and galleries as well as their exhibits. The e-culture environment offers user-friendly navigation techniques and contemporary multimedia tools and services for the better presentation and visualisation of the e-material to the users-visitors, paying particular attention to both common citizens and to disabled individuals, in order to offer them equal access to cultural heritage information. This environment is an inter-disciplinary application, combining the ICTs, cultural and e-inclusion domains (electronic support for disabled people).


This study proposes an earliest approach toward coordinated frequency stabilisation of wind turbine driven generator-tidal power generation-biodiesel driven generator-micro-turbine generator-based islanded two-area interconnected microgrid system with demand response support (DRS) mechanism. A recent bio-inspired optimisation technique, named yellow saddle goatfish algorithm (YSGA) is employed to optimally tune the controller gains. The comparative dynamic performance of conventional proportional–integral–derivative (CPID), fractional order (FO) PID, dual-stage PIFOD-one plus PI [PIFOD-(1 + PI)] controllers' parameters optimised by several algorithmic tools such as particle swarm optimisation, firefly algorithmic tool, salp swarm technique and YSGA clearly designates the superiority of YSGA-PIFOD-(1 + PI) controller under different scenarios (considering the real-time recorded wind and load data) in terms of change in frequency, tie-line power fluctuation and objective function. Furthermore, the impact of the DRS mechanism in both areas is analysed first time under real-time wind and load disturbances. Finally, the rigorous sensitivity analysis of YSGA-optimised PIFOD-(1 + PI) controller has been conducted with the variation of wind turbine driven generator gain, ±30% change in synchronising tie-line factor, frequency bias value, microgrid system time constant and  + 30% change in loading magnitude without retuning the optimal base condition values.


In this paper, we propose an approach to estimate the text skew for printed documents. This is an important step to prevent errors in further stages of an automatic document processing system (as text segmentation). Our approach is based on the statistical analysis of the height of the connected components. In a nutshell, our algorithm is comprised of four steps: (i) removal of redundant data; (ii) establishment of the connected components, which represent filled convex hulls around each text element; (iii) enlargement of these components using morphological erosion; (iv) removal of the largest connected component to identify the first estimation of text skew. According to it, the connected components are enlarged by oriented morphological erosion and the longest of them is extracted. Statistical moments are applied to this longest component to evaluate its orientation and the global text skew of the document is identified. At the end of this process, the original document is rotated back based on the calculated angle. The performance of the proposed algorithm is examined by testing on a custom dataset. The results support the robustness of our approach.