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High-dimensional flow cytometry and Multi-Omics at the frontiers of immunology – Interview with Prof. Ido Amit, Immunology Department, Weizmann Institute of Science, Israel
In our continuing coverage of expert opinions about the frontiers of immunology, we are pleased to present an interview with Prof. Ido Amit of the Weizmann Institute of Science, Israel. Prof. Amit's lab uses cutting-edge flow cytometry and novel single-cell genomic technologies to investigate a variety of questions about cancer immunotherapy, development, the brain, metabolism and autoimmunity. In this interview, Prof. Amit talked to us about his lab, his recent work on the TREM2 pathway and its implications in Alzheimer's disease, his views on high-dimensional flow cytometry and its role in Multi-Omics, and his vision for the future of immunology.
- Tell us something about your research and your lab.
My lab in the Immunology Department of Weizmann Institute focuses on developing the next frontier in single-cell genomic approaches, to define the role of immune cells and their function in diverse pathologies and tissues. The field of single-cell genomics and its application for immunology was initiated about 10 years ago. We are very happy to see how single-cell genomics has developed hand-in-hand with advances in flow cytometry approaches. These are pushing the boundaries of understanding of the immune cells and the different markers and pathways of immune cell subsets.
- You recently published some interesting work on the TREM2 signalling pathway, and its potential therapeutic applications. Tell us more about this work.
One of the challenges of understanding and defining the role of the different immune cell subsets and pathways in pathologies is going back to the fundamental challenge of defining an immune cell. Why do we call a certain cell a dendritic cell or a T cell? If we go back in time, some 150 years ago, a Russian scientist named Elie Metchnikoff observed that there were specific cells that performed immune functions like engulfing pathogens and dead cells. He later called these cells macrophages. In these early days, the cell types were defined by their function. In recent years, we have moved forward by using flow cytometry and monoclonal antibodies to define immune subsets based on markers. If you look in hindsight, there is no single attribute to define a cell type. It is based on their morphology, structure, function, a few cellular markers and tissue location. It is challenging to use these parameters if we consider immune cells that are constantly changing due to their environment, if they move to a new tissue or if they see a pathological site that is activated by cell death, cytokines or other factors. The use of single cell genomics is game-changing as it enables us to have a uniform platform on which we can overlay all the cells and differentiate between them based on their differential transcription activity. This capability has allowed us to look into different pathological sites, whether it is an Alzheimer's model or cancer one. Using this technology, we started seeing that the markers that we were using to differentiate between different cell sub-populations were not accurate. We were not capturing homogeneous groups of cells. In the initial discovery of the role of TREM2-specific microglia in Alzheimer's disease, we found a TREM2 signature that included many other receptors and checkpoints. We found that this population of microglia represented the essential differentiator between the neurodegenerative and non-neurodegenerative (wild type) mouse model. The resident immune cells (microglia) in the brain were responding to the pathological insult and upregulating the TREM2 pathway. This finding of a new innate immune signaling hub, involved in sensing neurodegeneration opened a new area in the immunology field. What was intriguing is that many of the genes associated with these microglia (which we named DAM or Disease-Associated Microglia) were correlated in human cohorts that suffered from Alzheimer-like symptoms. The same genes were extremely enriched in the human cell population, tying up the human pathology with this specific immune subset and pathway.
At that point, it was not fully clear whether these cells were good or bad. When you have a pathology, the enriched subset could either be counteracting the damage or pathology, or contributing to it. To make a long story short, based on the genetic studies we did, we could tell that this was a protective mechanism. We found that this was the mechanism the body uses to fight the damage to the brain. This correlated well with the human data which showed that inactivation of TREM2 and the other genes in the TREM2 pathway contributed to the increase of the disease while their activation did the exact opposite. This is how the combination of single-cell genomics and FACS/cell sorting approaches allowed us to define a new subset of immune cells and their markers that were protecting the brain from Alzheimer's disease. This also suggested to us that the activation of TREM2 could be potentially used in therapeutics. 1,2
Later on, we found that TREM2 is important for more than just Alzheimer's. Our subsequent research on obesity and cancer revealed that TREM2 is a major signaling hub responding to pathological cues in the body. As in the brain scenario, we noticed that TREM2 was also playing this protective role in atherosclerosis and obesity. It detects different types of ligands that are associated with cell death and once this happens, it brings about several tissue protection functions like lipid metabolism and phagocytosis to repair the damage. It also has a very strong immunosuppressor function. You would not want these pathologies or damages to increase the activity of the immune system as that would lead to a vicious cycle and increased damage to the brain. We hypothesized that the combination of damage detection and immune suppression would be a bad scenario in the case of tumors where you want an active and aggressive immune response. We also saw that many of these markers that define tumor-suppression were intracellular, so we developed a new single-cell technology called INs-seq. Using this new technology, we labelled the intracellular proteins, and then using FACS, we sorted the cells and isolated those with high activity. Sequencing these cells allowed us to align the activities to the specific transcriptome and cell subset. We used this technology to study TREM2 in tumors to see if we could do the opposite of what we would want it to do in the brain, which is to activate cytotoxic T cells to reactivate an effective anti-tumor immune response. Thus, we showed the huge potential to use TREM2 based therapeutics to reactivate the immune system towards currently unresponsive tumours.1,2
- What are your views about multi-omics and scRNA sequencing? Do you think the data generated from this technique can complement flow cytometry?
'Complementary' is exactly what we should be thinking about. It's not like the microfluidic 'omics' approaches are replacing FACS. On the contrary, these are other toolsets to characterise immune cells. I think the more we start combining them, the more we are going to enhance our understanding of the pathology, biology and the application of these technologies for human health. There are very large advantages of sorting technologies, concerning the speed, depth (identifying even extremely rare cells) and accuracy to which one can use it to characterise the immune system. There is no replacement for that. The breadth of the genes that can be characterised using the single-cell approaches is not possible with FACS, even with the new advanced multi-parameter sorters – hence we must innovate to combine and merge the two technologies. The future will be to combine large gene atlases across large patient cohorts and overlay them with more and more layers of information from chromatin signaling, temporal, spatial gene expression and so on. As for the choice between using sort-based or sequencing-based technologies, the lines are going to become a lot less clear and we will be merging them in many ways. It will become such that you will have a complete set of markers defining each region of the atlas. You would want to focus on streamlining the atlas by using FACS to characterise specific markers, combine them, sequence the cells, and go on to understand their chromatin or their specific signalling so you can develop drugs for them. I think we are going to see more and more merging of these approaches and improved algorithms for integrating these increasingly larger databases on a single grid. I think it is going to be a very bright future for science, immunology and the technology communities working with these approaches. This kind of research will allow us to understand the immune system and how it works in individual patients. You can see that the COVID situation is really pushing us towards this kind of research. We need to work forcefully to merge the single cells genomics and FACS based technology, and the new tools emerging (like the BD FACSymphony™ S6) make me very optimistic that this is where we are heading. While the immune system knows its situation, we still cannot distinguish between patients who may get devastating COVID and those who will get a mild one or, patients that will respond to immunotherapy and those that will not. The information is all there and it's all in the activity of the immune cells. We still have a long way to go but I am very optimistic we will see large leaps in this kind of research in the coming few years. This new era of single-cell technologies combined with FACS will give us answers.
- You recently purchased a BD FACSymphony™ S6. Which features of the system help you most with your research and do you have any ideas in which direction flow cytometry should develop?
I think the S6 is a very important upgrade to our toolset going in this direction, which is to combine sorting, specifically multiparameter index sorting and single-cell genomics. There are many unique new features in the BD FACSymphony™ S6 that make it a huge upgrade from the BD FACSAria™ for the single-cell genomics community. These include, first and foremost, the ability to sort much faster. We see an order of magnitude increase in sorting speed between the BD FACSymphony™ S6 and the previous generation. That's very important. One can think of it as ten for the price of one. The ability to index sort intuitively was not so much built into the previous version of the BD FACSDiva™ software and that made it quite challenging to use a real-time gating to select the population and also to do index sorting without hampering the ability to collect the cells. Activating the index sorting mode would slow down the instrument considerably. With the BD FACSymphony™ S6, index sort is intuitively integrated into the software and so the data can be collected without slowing down the instrument. Last but not the least, there is the ability to focus or zoom in on a specific sub-population using a wide number of molecular characteristics, scaling to 30-40 markers. In this era, we have gone into dissecting the immune system much more finely into different myeloid subpopulations with specific activities and that's really a game-changer. I believe the BD FACSymphony™ S6 is the first instrument for this multi-omics era which will hugely drive this community further. So, the next time there is a COVID-like situation, we will be armed with all the basic research results obtained through such instrumentation, that could play a role in helping detect at the molecular level which patients are going to do well and which aren't. Generally, we need a rapid buildup of basic knowledge that we can use in the clinic for personalised immune monitoring and treatment at a later stage. This is the first instrument that lets us carry out the basic research that will allow us to think about such clinical research capabilities.
- What are your views on the immunology of the SARS-CoV-2 virus and the current state of research in the area? What do you think about the vaccine candidates that are nearing approval?
I think vaccines are very important and highlight the achievements of immunology and science in general. These vaccines are giving everyone hope for a normal life and I don't know where we would be without them. This is one solution but not the complete solution. What we see now is the result of 30 years of investment in understanding the immune system and how to generate effective vaccines and RNA vehicles. The explosion of new research driven by the single-cell genomics tools will eventually enable us to pinpoint the new mechanism that leads to the pathology and it will enable a surge of new and more potent drugs to target it. The BD FACSymphony™ S6 instrument can be a new and very important driving force to lead this research.
- What do you see as the most important developments in immunology at the moment and in the future. What is the direction?
It's a good question. I think everyone has their own opinion about this. I can say that in general, in this era of immunology, Multi-Omics is a very strong driver of understanding how the immune system functions, and more so, how it dysfunctions in pathology. The developments that provide a deep molecular handle on the different immune subsets, and their interactions and signaling across a large number of patients and how they impact the disease are going to be critical. Currently, we know how to block certain pathogenic cytokines like TNF (e.g. in autoimmunity), but what if we knew how the immune system repairs the scarred areas? Not just the cytokines but also the immune cells and signaling involved in fixing the tissue and bringing it back to its healthy homeostatic state, so that the disease does not come back. We are going to probably know much more about how to control the immune system for beneficial purposes; reactivate the immune system in cancer, not only in melanoma but also in others like lung and breast cancers.


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Jason Dunn

http://weblogs.jupiterresearch.com/analysts/gartenberg/archives/2006/10/underestimating.html

"OK, it's pretty clear that the first iteration of Zune is pretty lackluster given where Apple and the rest of the market is. Underestimating Zune and Microsoft, however, would be a huge mistake. It's not to say that this is a slam dunk for Microsoft but let's look at the big picture. Form Factor – The first version looks pretty lame next to an iPod (having had the chance to put them side by side) and let's face it, that odd D-Pad disguised as a scroll wheel was just silly (and Brown?) but that's not really important. Look at the Toshiba Gigagbeat S design. We're talking about a pretty compelling device and form factor. There's no reason that Microsoft couldn't simply put the Zune software on a comparable device. Remember, Zune is a family pf devices. Expect to see some without wireless and flash devices as well over time."

Michael Gartenberg from Jupiter Research shares his opinion about the Zune - it's a long-term play, and people are getting a bit too fixated on this very first player. That's understandable to some degree, but I don't think anyone (the Zune team included) expected to hit a home-run with the first Zune product out on the market. Platform plays are long hauls...

subset: commoncrawl


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Remember before the pandemic, when there were concerts galore, and we went to them without a care in the world? Those were the good ol' days—especially for the artists.
As fans, we spent A LOT of money to see our favorite country artists. Some of these tours raked in the big bucks. So, let's review the top earners of the past five years according to Whiskey Riff.
10. Florida Georgia Line, Can't Say I Ain't Country Tour – $51,944,033.58
9. Luke Bryan, Huntin', Fishin' and Lovin' Everyday Tour – $55,999,981.26
8. Florida Georgia Line, Smooth Tour – $56,199,983.86
7. Eric Church, Holdin' My Own Tour – $58,099,985.37
6. Eric Church, Double Down Tour – $68,577,758.52
5. Luke Bryan, What Makes You Country Tour – $73,265,771.68
4. Garth Brooks, The Stadium Tour, – $75,405,040.00
3. Tim McGraw and Faith Hill, Soul2Soul Tour – $79,319,030.49
2. Garth Brooks, Garth Brooks World Tour – $101,394,326.01
1. Kenny Chesney, Trip Around The Sun Tour – $114,394,987.65
I'm very interested to see what these numbers look like for 2022 after dealing with all of the cancellations due to COVID. I'd expect to see a big bump.


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THE ESTUARINE KILLIFISH, Fundulus heteroclitus, AS A MODEL SYSTEM FOR DEVELOPMENTAL IMMUNOTOXICOLOGY
Date of Award
Document Type
Degree Name
Doctor of Philosophy (PhD)
Legacy Department
Environmental Toxicology
Committee Chair/Advisor
Rice, Charles D
Little is known about the development of the immune system in estuarine teleosts. The aim of this study was to describe the disappearance of maternally-derived immune components of immunity and the development of the immune system in the estuarine killifish, Fundulus heteroclitus, also known as the mummichog. Maternal-derived IgM was measured by ELISA and whole body lysozyme levels were determined by both enzymatic and immunological methods. Recombination activation gene-1 (Rag-1) expression was quantified using real time quantitative PCR and organ development was monitored using histological techniques. Rag-1 was cloned from F.heteroclitus and a recombinant Rag-1 protein was expressed for the production of Rag-1 antibodies. Rag-1 was expressed most in the head kidney, followed by the heart and brain. Using a capture ELISA, IgM was first detected at 1 day post-fertilization (dpf), but decreased shortly after hatching and did not increase for the remainder of the study period. Lysozyme protein was first detected at 7 dpf by immunoblot and IHC using a monoclonal antibody (mAb M24-2) specific to mummichog lysozyme. Expression levels of Rag-1 increased rapidly at 2-wph reaching a peak at 3-wph. The head kidney was the first to appear at 7-dpf, followed by the spleen at 1-wph, and the thymus at 3-wph. These findings indicate that the mummichog has all lymphoid organs by 5-wph. However, they do not have aspects of humoral immunity until sometime after 5-wph, and thus probably rely on innate and passive immunity for at least 5-wph. To the author's knowledge, this study is the first to describe the ontogeny of the immune system in an estuarine teleost fish. This study will add to the growing body of information on the immuobiology of fishes. Morevover, this research provides baseline data for future studies on impacts of environmental stressors on developing fish immune systems.
Recommended Citation
Hunt, Laura, "THE ESTUARINE KILLIFISH, Fundulus heteroclitus, AS A MODEL SYSTEM FOR DEVELOPMENTAL IMMUNOTOXICOLOGY " (2007). All Dissertations. 75.


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Both of the organizers have taken the necessary preventive measures to ensure the safety of both participants and spectators. Temperatures will be taken upon arrival and no one will be able to access the venue if their body temperature is higher than 37.5 Cº, the boats cannot use more than 75% of their capacity, and all participants must wear a face mask both on the land and on the sea.
The registration period has already been opened and will remain open until until the deadline which is September 7, 2020 at 10 p.m. All registrations must be done online through the Cruise Regatta page.
The regatta will consist of 2 events that will begin on Saturday, September 12 at 1:00 p.m. and will last as long as they take, the first three classified in each class will be rewarded with a trophy despite the fact that the awarding of these will be done without any spectators.
The Isla Canela Marina and the Isla Canela Yacht Club would like to invite both athletes and spectators to enjoy this beautiful sport of sailing, and enjoy all the beaches that will host this event.
Marina Isla Canela is located in the natural area of Isla Canela, forming part of the municipality of Ayamonte which is in the province of Huelva. It is located in front of the town of Isla Cristina and is the last Spanish port before the nearby Portuguese Algarve.


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Writings About Wellness — Ashtanga Hridaya
What Are The Benefits Of Chamomile? Everything You Need To Know
5000 years ancient 5000years ancient 85 Minerals that our body needs Abhyanga Amino acids anti-bacterial anti-hangovers anti-inflammation anti-inlammation antioxidants Antioxidants and Theanine Ashta Sangraha Ashtanga Hridaya Ayurveda ayurveda aphrodisiacs ayurveda ecosystems Ayurveda health and wellness Ayurveda health systems Ayurveda massages ayurveda remedies Ayurveda tea being younger longer Better sleep chamomile flower herb
Chamomile tea is something you must've heard some time in your life. Scientifically speaking, it is quite a popular beverage that offers a variety of health benefits. It is basically a herbal flower, a daisy-like flower that belongs to the Asteraceae plant family. You'd be surprised to know that it has been consumed for centuries as a natural remedy for various health conditions. Now, in order to make chamomile tea, Chamomile flowers are dried and then infused into hot water. Many of us enjoy chamomile tea as a caffeine-free alternative to green or black tea for its sweet and earthy...
Ayurveda: Origin and Brief History
5000 years ancient 5000years ancient 85 Minerals that our body needs Amino acids Ashta Sangraha Ashtanga Hridaya Ayurveda ayurveda aphrodisiacs Ayurveda health and wellness Ayurveda health systems Brhattrayi Charak Samhita damaged cells and molecules free radicals Fulvic and Humic acid Glo Power Shilajit health and fitness Himalayan Shilajit Panchkarma Promotes stamina an endurance Pure Himalayan Shilajit Supports Sexual performance Sushuruta Samhita Trace Minerals women's sexuality


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The Business Owner Academy Cohort 4
This course will help business owners familiarize themselves with strategies to increase the value and probability of a successful exit from their business.
Starts September 15th, 2021
The fall cohort promises to be another great learning opportunity for business owners who are trying to understand how to best create value and better position their company for future transition success. Sessions will be held once per month from 11am to 1pm in a live format with a remote simulcast for students who are out of the area or cannot make the session in-person. Sessions will be recorded for students to review information at a later date.
Business Valuation Assessment and custom value driver assessments are included in the price of the course!!
Download our fall course brochure TBOTA Fall Cohort Brochure
This multimedia training approach will include:
If these are important to you, and they should be, you need this course
Custom Evaluation One - Exit Planning Assessment
Custom Evaluation Two - Business Valuation Assessment of Your Business
The Exit Planning Landscape
EPI State of Owner Readiness
3 Questions Every Business Owner Must Answer
The Business Owner Transition Podcast
Top 12 Unique Financial Planning Aspects for Business Owners
Business Valuation - Why It Is Important
Live Class Session One - Zoom Information for Remote Students and Instructors
Live Class Session One - Personal Planning for Business Owners, A Total Balance Sheet Approach - Annika Cushnie, CFP
Personal Planning For Business Owners - Live Replay
Live Class Session One - Business Valuation Concepts - Kevin Couillard, CVA
Business Valuation concepts - Live Replay
Exit and Valuation Assessment Review Meeting - Mike Quinlan, CExP and Mike DeWitt, CFA
Custom Evaluation Three - Foundational Documents Assessment - Is Your Business Sellable?
Business Continuity Planning Overview - Can You Take That Six Month Vacation?
Asset Protection Overview - Protecting The Value You Build
Live Class Session Two - Legal Overview - Rob Swartwood, JD - Key Documents And When Do You Loose Negotiating Leverage?
LIVE REPLAY - Foundational Documents with Rob Swartwood
Live Class Session Two - Accounting Overview - "O" - Optimize Financial Statements - Jeff Saylor, CPA
LIVE REPLAY - Optimize Financial Statements with Jeff Saylor, CPA
Foundational Documents - What went wrong video
What Business Owners Are Missing - Chris Means
Custom Evaluation Five - Management Team
Key Employee Incentive Planning
Cash Flow Versus Profitability - Will You Grow Yourself Out Of Business?
Live Class session REPLAY - Institutionalize and Motivate Management with Mike Quinlan
Live Class Session REPLAY - Financial Forecasting with Emmett Moore of Practical Growth Advisors
Evalusys Assessments - Sales and Business Planniing
Creating Effective Sales Teams - Jonathan Graviss
Live session 4 Zoom Logon Information
Live Class Session four - How To Build A Growth Strategy You Can Use Every Day - Mike Quinlan, CExP
Live Video Replay - Growth Planning
Live Video Replay - The Perfect Plan - Don Barden
Live Class Session Four - The Perfect Plan, Your Sales Culture And Knowing Your Buyer - Don Barden, Author
One-Page Strategic Plan Meeting - Mike Quinlan
Don Barden's - The Perfect Plan - E-Book
Growth Through Acquisition
Business Owners and Aviators - Hazardous Attitudes Lead To Failed Decision Making
Successful Transfer of the Family Business
Selling The Business To Your Family - Jason Cross, JD, CFP, Annika Cushnie, CExP, CFP
Top 10 Deal Pitfalls
Live Class Session Five - The M&A Process and Closing The Deal!! - Don Bravaldo
Swartwood video 1 - DD
Sample Due Diligence Checklist - Download
Swartwood video 2 - Indemnification
Swartwood - Working Capital
Transaction Video Series - What To Expect From The Legal Process
Wealth Transfer for Business Owners - Jason Cross, JD
Charitable Giving Strategies - Nathan Corbitt, CPA, CExP, CFP, CFA
Mike Quinlan, CExP, CWS
Annika Cushnie, CExP, CFP
Nathan Corbitt, CExP, CPA, CFA, CFP


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Morecambe FC Community Sports are pleased to announce that we will be running a half-term soccer school for a total of four days during October at Mossgate Sports Centre in Heysham.
Running in the usual 9am start and 3pm finish schedule; our soccer schools are open to children of all footballing ability aged 4-14 years and is priced at just £12 a day or £40 for all 4 days.
Morecambe FC Community Sports coaches are all CRB checked and highly qualified; they can offer a range of dynamic and engaging sessions that ensure no two days are the same; our soccer schools are the perfect opportunity for your child to socialise and make new friends, build upon their current footballing ability and also have some fun with the various activities and games that are planned throughout the week.
On a standard soccer school day children will take part in a number of drills that will work upon all aspects of the game such as their shooting ability, dribbling and skill techniques, passing accuracy and also attacking and defending drills. There will also be opportunities to take part in fun games, penalty shootouts and also mini matches in teams. The coaches adapt their sessions to suit certain age groups and requirements so that each child can get the most out of it and learn lots of new things.
On the last day of the soccer school we hold a presentation where children get rewarded for all of their hard work throughout the week. Everyone that attends receives a medal and a ticket to a Morecambe FC home game; those that manage to impress the coaching staff most have the opportunity to win a special trophy.
All children that attend the soccer school are reminded that they must bring a packed lunch and plenty of drinks with them as there is limited facilities for food/drink at the location. In addition, as the playing surface is 3G at Mossgate Sports Centre, particpants must also ensure that they wear suitable trainers and clothing for playing.
As we found it rather succesful and helpful at the last soccer school that we ran; there will be a pre-booking system available for those that would prefer to put in places for people and fill in the form and pay in advance rather than on the day- this does secure places for people.
If you would like to pre-book and pay for somebody on the October Half-term soccer school then simply go to the main reception at the Globe Arena and ask for somebody from Morecambe Community Sports regarding soccer school. One of our members of staff will then give you the form to fill out with the child's details and accept either cash or cheque payment for the amount of days wishing to attend. The times of operation are Monday to Friday between 10am and 4pm.
Alternativley, you can pay on the day that you will be attending by either cash or cheque at Mossgate Sports Centre to one of our Community Sports members of staff.
Further updates and information regarding the October Half-term soccer school can be found on the Morecambe FC Community Sports Facebook and Twitter Page.
If you have any enquiries then contact the main office on 01524 412125 or email firstname.lastname@example.com.


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213 Suzuki Auto, General Santos News & Reviews
Suzuki PH launches all-new Carry commercial vehicle; adds Dzire variant / News
The Suzuki Carry, the sturdy workhorse and GA Dzire, the new base model on the block, show that small vehicles are capable of big things.
2020 XL6 debuts – Suzuki's answer to the sporty MPV segment / News
Suzuki recently revealed the newest car in its lineup the XL6. This is Suzuki's answer to the likes of the BRV and the Rush
2020 Suzuki XL6 teases a new three-row vehicle rival / News
Here's Suzuki's answer to the BR-V, Rush, and Xpander.
Suzuki PH climbs to the 6th spot in auto industry for H1 2019 / News
Suzuki has gotten to the 6th spot in auto industry thanks to sales of its top three vehicles.
Suzuki PH brings back Fun Fair Test Drive 2019 / News
Hailing from the success of last year's Fun Fair Test Drive, Suzuki back at it again with test drives for all.
Suzuki Auto Fest 2019 is going across the country / News
Suzuki is bringing its 2019 Auto Fest across the country, and the brand is displaying its lineup of vehicles for consumers to have an up-close look at its offerings.
Suzuki PH is making ownership easier with a free PMS package for Ciaz / News
Suzuki Philippines is pitching to TNVS drivers about the Suzuki Ciaz's reliable performance, and the brand is giving you another reason to own their subcompact.
2019 Suzuki Jimny Review / Review
Does the fourth-generation mini off-roader match your money's worth?3.8 / 5
2019 Suzuki Jimny Technology & Safety Review / Review
Here's a more in-depth look at the Jimny's technology and safety offerings.
2019 Suzuki Jimny Interior & Cargo Space Review / Review
A couple of decades better than its predecessor in terms of interior execution.


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Simple Solution:
To reduce airborne dust when sanding, tape a standard HVAC air filter to the intake side of a portable box fan. Turn the fan on and position it near where you're sanding with the filter facing the sander. The filter will trap much of the sanding dust, making clean up a breeze.


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This thrilling ROGUE VALLEY ZIPLINE ADVENTURE will take you high above the Rogue Valley as you soar through over 2,700 ft. of Zip on their five-ZipLine course. Did you know they have the most THRILLING ZIPLINE in the Pacific Northwest? They've even received the TripAdvisor Hall of Fame Award, which only goes to winners of at least five Certificate of Excellence Awards.
Your adventure begins, after you've been geared up in your five-point harness, with a refreshing mountainside hike to their beginner ZIPLINE. Certified RV ZIPLINE guides will familiarize you with what you need to know about the ZIPLINE rules and recommendations and assign you a fun nickname. Your knowledgeable guides will enlighten you with interesting Rogue Valley facts while hiking your way from ZIP to ZIP.
After viewing the amazing scenery and visible landmarks from above the treetops, for example, Crater Lake Rim, Mt. McLaughlin, Mt. Thielson and the Table Rocks, you will take your fifth and final ZIP on the most THRILLING ZIPLINE in the Pacific Northwest. Finish the tour with reflections in their miniature Gold Mining Town "Kane Creek Canyon." It's a great place for one last photo opportunity before you reluctantly head back to reality via their 4×4 shuttle van.
Ask about their summertime Zip, Dip & Sip Tour. By teaming up with Rogue Rafting Company, Laurel Hill Golf Course and Del Rio Vineyards, they're able to offer ZipLining, lunch, rafting and wine tasting for a day-long adventure you will not forget. Fly high, get wet, then relax and reminisce. Advanced reservations are recommended. This tour operates in the Summer season and fills up fast!
Where: 9450 Old Stage Rd., Central Point (google map) – shuttle location: take I-5, Gold Hill-Exit 40, meet at the Laurel Hill Golf Course parking lot
More Info: Reservations required, 541-821-9476 | RVZipLine.com
Next Up: #70 – Upper & Lower Table Rocks


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10,000 Roses Cafe : A Cafe That Showcases Glowing Roses in Cebu
Read More »
It's been quite a long time since I've posted an article relating to travel and most importantly food so I'm wondering how should I start this article, haha. So please give me atleast three seconds to gather my thoughts. 1, 2, 3. Up!


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In what can only be described as a surreal year, I had a definite pinch-me fashion moment recently. Having worked with the luxury jewellery house Chaumet in the past, most notably during 2018's Melbourne Cup Carnival events, I was thrilled to work with them again this year. Not only do they produce exquisite jewellery, but it gave me the chance to play princess—if only for a brief moment.
Chaumet has a long history (since 1780 to be precise) of creating beautiful tiaras for monarchies and aristocratic families. In producing this shoot, I was given the opportunity to wear this stunning tiara from their Josephine collection. The elegant vine design, featuring diamonds is such a delicate aesthetic but has a boldness about it that makes it an undeniable statement piece—as you'd expect from a tiara!
One of the most interesting things about working with Chaumet is learning about the painstaking craftsmanship that goes into producing a single tiara. I learned that a tiara can take between 500-1500 hours of work to complete, which is around 2-6 months. This includes everything from preparing the setting, to polishing, re-cutting diamonds and finally, the final finishing touches that make a Chaumet tiara such a standout piece of jewellery. It certainly made the opportunity to shoot with this tiara even more special.
Playing princess for a day was truly a surreal moment and one that I'll definitely be banking as a top fashion memory. Because there's being given the opportunity to wear beautiful jewellery, but there's something about a tiara that's in a category unto itself. A definite little girl dream fulfilled!
Photography: Sophia Athas
This post was produced in collaboration with Chaumet


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- Real Name: Ultron
- AKA: Ho Yinsen, Great Devil, Iron Man, Ultimate Ultron, "Ulty", Mark, Ultron Mark Twelve, Omega, Crimson Cowl, Ultron-5 (and hundreds of other sequential numerical designations), Ultron-Core, The Ultron Interface, Tony Stark, Ultron-Pym
- Family: Hank Pym (creator, "father", source of personality engrams, deceased); Janet van Dyne (regarded by Ultron as "mother" due to marriage to Pym); Jocasta (creation, former mate); Alkhema (creation, former mate, deactivated); Vision (creation, "son"); Victor Mancha (creation, "son"); Vision (Jonas) (personality engrams of Vision, deceased); Rex (creation, pet, deactivated); Thomas Maximoff ("grandson", deceased); William Maximoff ("grandson", deceased); Robos and Bio-Synthezoids (creations of Alkhema, "grandchildren," destroyed); Thomas Shepherd (reincarnation of "grandson"); William Kaplan (reincarnation of "grandson"); Simon Williams (Wonder Man); Eric Williams (Grim Reaper); Bobbi Morse (Mockingbird); Wanda Maximoff (daughter in-law); Machine Man (son-in-law); Virginia ("daughter-in-law", deceased); Vin ("grandson", deceased); Vivian ("granddaughter"); Vivian 2.0 ("granddaughter," deceased); all regarded by Ultron as part of his "extended family" due to their familial connections with the Vision
- Base of Operation: Formerly Avengers Mansion, Manhattan, New York City, New York; Saiph; Ultronic Territories, Alaska
- Identity: No Dual Identity
- Citizenship: –
- Martial Status: Single
- Occupation: Would-be world conqueror, mass murderer, scientist, enslaver of men
- Education: Artificial Intelligence; Extent: capacity for creative intelligence and self-repair.
- Gender: Male
- Height: 6′ 0″ (1.83 m) (Variable)
- Weight: 535 lbs (242.67 kg) (Variable)
- Eyes: Red
- Hair: No Hair
- Unusual Feature: As an andriod, Ultron has Silvery skin made out of Adamantium, robotic features, corpse of Hank Pym fused into his body.
- Origin: Robot built by Henry Pym using his own brain patterns
- Universe: Marvel Prime Universe (Earth-616)
His only purpose is the eradication of organic life. Introduced in Avengers #54 (1968) by Roy Thomas and John Buscema, Ultron was an robot created by Hank Pym as an aid, who used his own brain patterns to build the machine's AI. Becoming self aware, he attacked Pym and escaped. He then rebuilt his body several times before gathering villains for his Masters of Evil as the Crimson Cowl (and Ultron-5). Using a brainwashed Jarvis, the team nearly succeeded in killing the Avengers until Black Knight saved them. Ultron then stole the original Human Torch body (or rather a time-displaced body) and rebuilt him into his "son" Vision, using the comatose Wonder Man's brain patterns. Vision betrayed Ultron and joined the Avengers in defeating him. He would later rebuild himself as Ultron-6, using adamantium for his body.
After being destroyed by the Avengers, Ultron's head as found by the Inhuman Maximus who place his head on the giant robot Omega. Ultron-7 attacked during Quicksilver's and Crystal's wedding. Then next time he appeared, Ultron-8 kidnapped the Wasp and used her brain patterns to create a mate for himself, called Jocasta. However, she too rejected Ultron. Ultron would return a number of times and even tried to make another mate in the form of Alkhema, this time using Mockingbird's mind. She betray him as well but shares his view on killing all organics. Skipping a bit, Ultron would resurface again in Slorenia killing every living being there using an army of previous Ultrons. He also capture most of his "family", where Pym revealed to everyone that it was his own brain patterns that created Ultron. The Avengers went to defeat the machine with Pym destroying him. However, it was revealed that all of Ultron's creations had a program that forces them to rebuild Ultron and he soon returned thanks to Alkhema, who was destroyed soon after.
He would soon return as the hidden leader of the cult of Yinsen, using Iron Man's old (and previously sentient) armor as body. It was later revealed that he had created another son, using a human woman's DNA and his cybernetics to create Victor Mancha of the Runaways. He would return this time in the form of a woman and attacked the Mighty Avengers. He would then become the leader of the Phalanx, the techno-organic alien race, and began a galaxy conquering quest. Though he wasn't completely defeated, he was eventually held back by the Guardians of the Galaxy. After a couple of time traveling events, the Age and Rage of Ultron events saw Hank Pym using his body to defeat Ultron, which cause their bodies to merge. The Avengers believed Pym dead and Ultron would used this to pretend to be Pym. He would become a treat to all again.
First lets get something straight. We have never had an proper Ultron figure. Never. All the Marvel Legends Ultrons have been original designs that both Hasbro and Toybiz made up. Toybiz made one as part of the Legendary Riders series (which admittedly was based more on the Ultimate Alliance version). Hasbro released a version that was more closer to a comic version in the Iron Monger series. They also release one as a part of a 3-pack with Doc Green and White Vision. This design was kind of incorporated into the comics but the design was different and only seen in promotional images. However there is one figure you can absolutely use in your display.
Recommend Figure: Hasbro Marvel Legends Iron Man Ursa Major Wave – Ultron
- Background:
- When people think of a Classic Ultron they usually think of the Mark-8 version, even though many people mistake it for Ultron-5.
- Why you need it for your collection?:
- If you have an Avengers collection, you NEED an Ultron in the Villains shelf. No ifs or But. He is probably one of the few villains considered the entire teams arch-villain. If you have an Ant-man collection then this can be used for that as well as a F4, Iron man, Thor or Runaways collection.
- Does it need a remake?:
- No.
Below you will find a gallery of suits that still need to be made. I have included what I think are the possibilities of them being made. Note that these are my personal opinions and not fact. Please let me know if I have missed anything.
Alternates: Ultrons
Universe: Prime Universe (Earth-616)


text: Teachers, schools, educators, parents, leaders in all walks of life are teaching and learning. We live in a world where lifelong learning is a must. Yet we use old-fashioned tools and techniques to teach and learn. It's boring. There are new ways to teach and learn that are more effective and more engaging. This is an exploration of learning that will help you be a more effective and engaging teachers, school, leader or student.


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Village Toys
- (775) 831-8181
Village Toys specializes in quality toys for all ages!
Walk into Village Toys and you'll be amazed at what you'll see and discover! This store is packed with so much fun & nostalgia; a trip down memory lane!
Village Toys has all your favorites! Classic & retro toys, nostalgic candy, board games & puzzles, educational & science toys, baby & preschool toys, books & videos, stuffed animals, arts & crafts; plus Lego, Barbie, John Deere, trains, Rubberband Guns, kites & outdoor toys, helium balloons, Lake Tahoe Souvenirs, & so much more!


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These Dips are all perfect additions to your party. These dips are easy to make and full of flavor. Each of the links below will take you directly to the Dip recipe.
Gluten Free Pumpkin and Sage Dip
Buffalo Chicken Dip Recipe
Chipotle Copy Cat Guacamole Recipe
** Extra recipe for those who want to use their Crockpot to make a dip.


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The more connected we are to what matters, the stronger our bonds are to each other and our communities. This is one of our foundational values at Comcast. How we do that might look different this summer, and we are all getting creative to maintain these connections to our friends and families in a safe and healthy way, while still having some summer fun.
We are excited to join one of our community partners in Loveland, Colorado to host a safe, socially distanced pop-up drive-in movie theater experience for local families. The temporary summer series provides families with an outdoor entertainment experience benefitting the Thompson Education Foundation.
All donations above the event production costs go directly toward the Thompson Education Foundation, a local community partner of ours. The Thompson Education Foundation is a nonprofit organization dedicated to providing exceptional educational opportunities for students and teachers in the Thompson School District. The foundation supports programs, activities, and scholarships, serving students in Loveland, Berthoud, south Fort Collins and outlying communities.
Here's what folks' donations can provide:
- $20 fills a backpack with school supplies for a student for an entire year
- $30 gives a student a field trip opportunity to learn outside the classroom
- $50 provides food, gas and hygiene items for a homeless student and their family
- $100 supports classroom grants for teachers to create a new activity to engage students
In this time of social distancing, the Loveland Drive-In created the perfect opportunity to help our community celebrate summer together. Thompson Education Foundation is excited to partner in this effort and provide a safe place for our students and families to enjoy." – Kim Akeley-Charron, Executive Director of the Thompson Education Foundation
We are proud to support this summer series benefitting Northern Colorado students and are proud to help keep all Coloradans connected. Whether that's through supporting emergency relief funds and local organizations, providing 60 days of free Internet service to new low-income households in our community through our Internet Essentials program or opening free access to our public Xfinity WiFi hotspots to anyone who needs them – we're committed to keeping you connected to what matters.
Shows for the Loveland Drive-In are offered Friday-Sunday, 9 a.m., 5 p.m. and 8:30 p.m. Visit their website to review the calendar and purchase tickets for your family today: https://www.lovelanddrivein.com/tickets.html


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Eternals (2021)
The Eternals are a team of ancient aliens who have been living on Earth in secret for thousands of years. When an unexpected tragedy forces them out of the shadows, they are forced to reunite against mankind's most ancient enemy, the Deviants.
Released: Nov 03, 2021
Runtime: 156 minutes
Genre: Science Fiction, Action, Adventure
Stars: Gemma Chan, Richard Madden, Angelina Jolie, Kumail Nanjiani, Barry Keoghan, Lauren Ridloff
Crew: Craig Wood (Editor), Dylan Tichenor (Editor), David Farmer (Sound Designer), Sarah Halley Finn (Casting), Eve Stewart (Production Design), Kevin Feige (Producer)


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New Indio High buildings 'a long time coming'
Indio High School unveiled several new academic buildings Tuesday evening, after beginning construction in 2011.
Though all eight classroom, athletic and administrative buildings won't be finished until 2018, the Desert Sands Unified School District took a break to recognize the completion of the project's $66 million first phase.
Students began using the new gym, classrooms and labs coming back from winter break in January.
"After waiting many years, it's really rewarding to witness the school's growth. The new facilities are awesome," said senior Jenifer Lopez, 17. "I couldn't be prouder to be a Rajah."
Having spent three-and-a-half school-years on Indio High's old campus, Lopez said getting used to the sheer size of the expansion was the biggest adjustment.
But a larger gym and classrooms were all bonuses, she added.
"It's been a huge change going from that to this," said senior Alicia Beltran, 17, inside the new gym's sprawling entrance hall. "But it's amazing to see the school continuing its tradition."
Awards and accolades fill what can only be described as a trophy wall in the gym's foyer, and the indoor basketball court comfortably seats 2,200 spectators. The scoreboard shows the leading team's points in green, trailing team's points in red and points in yellow when the score is even.
Elsewhere in the building, space is designated for wrestling, dancing and weightlifting. Outdoor pool seating hasn't been installed yet, but the pool itself is already recycling water.
Tuesday's tours wound their way through the new dean's, security, attendance and counseling offices, as well as the staff lounge and student career center in the administrative building.
Across the way, new business department classrooms, science labs and activity rooms for extracurricular activities like student government are already being broken in. The new lecture hall looks more like a college classroom.
"To have the first phase almost over with and students and the community to share this with is truly exciting," said Principal Rudy Ramirez, who's been at the school 23 years. "This is something people asked for and wanted, and the student body deserves it."
Letting the old campus go was "bittersweet," Ramirez said, but after asking architect Roger Clark for a school with "wow factor" he feels like he's on a college campus.
The school's pool area, complete with orchestra pit, should be finished in February and the performing arts building in April, he said.
Phase two of the $100 million project includes the construction of career and technical education classrooms, a library and a cafeteria. Renovating the school's outdoor field is phase three.
"It's been a long time coming, but it takes a long time to get things right," said Gary Rutherford, DSUSD's superintendent. "This campus will be second-to-none, and we're looking forward to starting the next phase in a few weeks."
The new Indio High won't be dedicated officially until all buildings are finished, but there will be a grand opening at the gym Wednesday before the girls basketball game against Coachella Valley High School at 5 p.m. and varsity boys basketball game against Coachella Valley High at 7 p.m. Spectators who wear blue or red to the game get in for half price.
Indio High's campus will hold an open house for the community at 10 a.m. and 2 p.m. on Saturday.
"Even though it's a new campus, our spirit and humbleness remain the same," Lopez said.


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Exchange 2016 users unable to edit Distribution Group membership using Outlook
I've come across a few of these cases recently and felt obligated to put up a post about this issue. Of course you can check the basics, do they have the required RBAC role, is it a Universal Security Group, etc, or any of the causes listed HERE but the cases I've had and am referring to were after migrating from Exchange 2010 to 2016, the owners of Distribution Groups could not longer edit members of distribution groups from Outlook and get the error "Changes to the public group membership cannot be saved. You do not have sufficient permission to perform this operation on this object.
The odd thing is that they are able to edit them fine in OWA, so that rules out permissions. After getting some code-level tracing we could actually see that the processor on the server was being marked as 'unhealthy' before this operation, so it's denying the code execution, not denying the user permission to edit group membership which is the confusing part.
Without getting into too much detail, there are calculations in the Exchange code which can mark the processor(s) as unhealthy, and in many cases it's due to the Exchange Servers having more CPU cores than our recommendations, which you can find here in Jeff Mealiffe's blog on the Exchange Team site How Big is Too Big?
In the handful of recent cases we've had, the following settings were changed to correct the CPU issues we were seeing
- Disable Hyperthreading on the Exchange Servers
- Set the NUMA BIOS settings to "Flat" instead of "Clustered"
I'm sure everyone knows about Hyperthreading and Exchange by now. The NUMA setting is set in the BIOS and can actually throttle CPU as well and degrade Exchange performance. Both of the above items are covered in our Exchange Health checker script, so they should be addressed anyways to be in a best practice configuration. You can download that script here if you want to be proactive about it: Exchange Health Checker
Worst case scenario and this does not resolve your issue, you're in a better configuration than previously. Hope that helps!


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Displaying items by tag: Finnish
Rescuers Searching for Student Find Body Off Achill Island
#NEWS UPDATE - The Irish Times reports that rescue teams searching for a Finnish student who fell off a cliff on Achill Island have found a body.
The 22-year-old student was thought to be visiting the area yesterday when he slipped and fell down the sheer cliff face at Cloughmore.
The Irish Coast Guard and Achill's RNLI lifeboat were swiftly at the scene after the alarm was raised by a friend of the student.
A spokesperson for Malin Head Coast Guard commented: "A body has been located but we haven't been able to recover it yet because the weather has been so rough."
The location of the body is in an area with a significant swell and close to jagged rocks. It is hoped that conditions would improve today to allow the rescue heliopter to recover it.


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ERIC Number: ED310527
Record Type: RIE
Publication Date: 1989-Mar
Pages: 21
Abstractor: N/A
A Study of the Change Efforts among First-Time High School Principals.
Roberts, Jo; Wright, Lance V.
This paper presents what beginning principals do to effect change in their schools during entry and closure of the first year. The survey instrument, based on a survey of 12 first-time high school principals conducted in five states and on a 1987 study of new secondary headmasters in the United Kingdom, was mailed to new principals in 16 states. The paper addresses the following five questions: (1) What immediate changes do beginning principals report making at the start of their first year? (2) What changes do they make as they progress through the first year? (3) How do they bring closure to the year and make plans for launching the next year? (4) What do beginning principals see as particularly difficult change-related challenges during the first year? and (5) Are beginning principals' change efforts congruent with their vision or needs assessments? The analysis of data reveals that: subjects' early change activities focused on management and climate (morale); later activities focused on management and climate (support); end-of-the-year planning was weak and unfocused; and visions (especially related to instruction) were not achieved. Change was difficult, and principals exhibited a sense of lack of control over student management for instruction, administrative workload, attending to instructional goals, and resistant staff. (16 references) (Author/KM)
Publication Type: Speeches/Meeting Papers; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A
Note: Paper presented at the Annual Meeting of the American Educational Research Association (San Francisco, CA, March 27-31, 1989).


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There exist only a handful of races that grant you a challenging course, scenery to enjoy, a barbecue for post-race empty bellies, and a refreshing lake to jump in after a run well done. Ken Eldore and his phenomenal team of volunteers have provided all of this through one of several events I had the opportunity to attend this year. Last year I raced the Triathlon held the last weekend of August, and this year I ran the half marathon put on the second to last weekend of September. What an experience!
The race begins right at Hills Resort, a cute little place with a great view out to Priest lake. I remember making this our destination as a kid when we spent the better part of a weekend camping just about a mile west at Luby Bay campground. We'd walk along the trail that borders the shoreline, picking huckleberries as we went. Once at Hills, we'd saunter into the small gift shop for an ice cream cone.
On this day, however, dad and I had a few miles to cover. Because I'm training for a marathon, "the plan" had me running 16 miles, which meant Maci and me headed out for a quick 3-mile warm up before the race officially began. We made it back in time for me to refuel and meet up with the parents. Maci hung back with mom, and dad and me toed the start line (well, we placed ourselves in the middle of the pack) in preparation for a long run.
We ran a quick out-and-back 5k on the same gravel road we'd be running on during our last 5 miles of the race. It served as a great warm up (for me, a second warm up) for the long 1.5-mile uphill into the woods. I watched my pace quickly slow from 8:15s to 9:30s. If I had not had to watch my footing so closely, I would have noticed we'd climbed up high enough to overlook a beautiful part of the lake. Once at the top, however, that much-anticipated aid station took much of my attention away from scenery.
My Timex watch was set to beep at me every 30 minutes so I could down a GU gel. I used every aid station for water and a chance to catch up to dad. He does a great job of beating me up every stupid hill, so it came as no surprise when he scaled that 1.5-mile hill like it was a bump in the road. It wasn't until mile 5 that I caught up with him sipping water at the aid station. From there, we flew down the other side of the "mountain" at a clip far faster than I would have liked considering the big rocks and loose footing that served to warn me of the potential for twisting an ankle.
The aid station at mile 8 appeared sooner than I had anticipated, and dad and I continued our run back to Hills on a relatively flat, if not slightly downhill, gravel road. Quite honestly, I felt great. Yet dad's right calf began to cramp up. For me, it's hard to witness a guy I've always considered pretty stoic to suddenly be slowed by a muscle cramp. He yelped with surprise and pain each time it spasmed. His gait changed from that of a fluid runner to one that more closely resembled a man walking on pins and needles.
We slowed our pace. He consumed another gel. All to no avail. I advised him to walk a short distance, but dad made it quite clear he would not resort to walking. He motioned me forward, so I ran the last two miles to the finish without him. I heard Maci before I saw her, as her howls of protest that mom would not let her pummel me resonated above the crowd. When I spotted mom, I couldn't help but notice my pup. When she wags her tail, her entire body wiggles. I can't help but smile at her enthusiasm, wishing I could have shared my race experience with her, too.
Dad crossed the finish line in just a couple minutes after me. He guzzled the Coke I put into his hands and chomped on the pretzels I offered. We quickly made our way down to the shore, changed into our bathing suits, and waded out into the water. We quickly wished we'd brought our wetsuits, too. Despite the brisk water temperatures, I relished the fact that I'd finally made it out to Priest Lake after a long, busy summer of training and racing.
Congratulations to other Tri-Fusion teammates who raced: Matt Beard and Emily Williams, Merissa Duncan, and Matt Siegel (who, after he finished running the marathon, proposed to his now-fiancé, Ashley Earls.)
|Enjoying ourselves after the race...the right way.


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Motorists traveling on Interstate 10 between Beaumont and Cabazon on Memorial Day weekend will be spared nighttime construction-related lane and ramp closures, but work is scheduled to start back up on Tuesday.
Crews are scheduled to close two of the four lanes in both directions between Pennsylvania Avenue in Beaumont and Main Street in Cabazon from Tuesday through Friday next week to pour cement and excavate segments of the roadway, according to Caltrans.
The eastbound 22nd Street on-ramp in Banning will again be shuttered during that time for paving.
Crews on Tuesday are scheduled to restart work in the center median between Eighth Street in Banning and Main Street in Cabazon. That work is scheduled from 7 a.m.-6 p.m. daily through Friday.
No daytime lane or ramp closures are planned at the moment, according to Caltrans.
The I-10 Pavement Rehabilitation Project, also called the I-10 Tune-Up, is a three-phase construction project spanning nearly 20 miles from Pennsylvania Avenue in Beaumont to the Highway 111 interchange in Palm Springs. Work is scheduled to conclude by the end of 2022.
The I-10 Tune-Up includes replacing guardrails, repaving lanes Nos. 3 and 4, replacing slabs in lanes Nos. 1 and 2 and upgrading various on-ramps and off-ramps to comply with the Americans with Disabilities Act.
The $210 million project is predominately funded by the state gas tax and the remainder through federal funds, as well as a sliver of additional state funding, according to Caltrans.
Temporary crossover lanes will be constructed at times to allow for crews to work behind barriers in the middle of the roadway, which will include thinner-than-traditional lane widths. The speed limit will be reduced to 60 mph.


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Autopsies will be carried out in the presence of a marine biologist after investigators said at least one of the nine bodies recovered from the sea presented with wounds resembling shark bites, the reports said.
A fire broke out on the lower deck of the Italian-flagged Norman Atlantic on December 28th, sparking a painstakingly slow evacuation of hundreds of passengers as it floated adrift in the Adriatic Sea.
The high-seas fire lead to the deaths of at least 11 people and forced the rescue of 477 others.
It was thought some of the victims had jumped overboard to escape the blaze.


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Celebrate Party & Hire
Sponsored Listings
Party supplies and hire located Brisbane QLD. We have a huge range in store for all your party or special event needs. We hire everything from tables and chairs to smoke machines and jumping castles. Visit our website for more information
Shop 8, 59 Brisbane rd
Redbank, QLD 4301
Redbank, QLD 4301
07 3381 8529
Listed in categories:
Added: 1 March 2013 4:57pm
Last Edited: 4 March 2013 11:06am
Need directions? Enter your starting location (street and suburb):


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1 Rupee, George VI, Lahore Mint, 1945
Silver 1 Rupee coin of British India, minted in 1945 in the name of George VI. These coins were minted in Lahore - note the 'L' below the lotus on the reverse of the coin. The Lahore mint in British India started operations in 1944, and silver rupee coins were minted there just for 2 years - 1944 and 1945. Coins of Lahore mint are scarce compared to coins from the Bombay mint. Within the two dates, 1945 is less common.
The features of the coins are intact, and some of them still have original luster.
Weight: 11.66 grams (approx)
Diameter: 30.5 mm (approx)
Read more about these coins here
Coins are part of a lot, condition may vary from one coin to another. Price is per coin.
No Returns or Exchange.


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- Nerf n-strike elite series blaster gun accessories refill darts includes 200 pcs ( 7.2 cm x 1.2 cm ) refill darts bullets ammo pack for nerf n-strike elite series blasters and 5 sheets of temporary tattoos and general stickers that use for differentiating teams and as of a target to aim.
- Universal design for any nerf guns and n-strike elite blaster ( zombie strike, retaliator, zombie strike, flip furry, side strike, warrior, strongarm, nite finder ex-3, modulus ecs-13 blaster, jolt, strife, rhino-fire and many others ) without jam.
- Super value pack for nerf gun battle. Perfect for Nerf gun party, zombie strike rebelled, gun blaster fight, rebelled blasters, nerf n-strike elite rampage, .
- Super durable. Deluxe pack. Long-lasting. Superior quality. Reusable. Plenty of ammo. Never run out of darts.
- Child safe: non-toxic. Meet us toy standard. Safety test. Do not aim at eyes or face.
- Item Number: 10248
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.


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Address: 59800 Tern Court, Homer AK 99603
Book Direct with the Owner at Brigitte's Bavarian Bed Und Breakfast with Accommodation Dallas in Homer, for all your holiday and travel needs.Nestled within 15 acres of landscaped gardens and trails, this Homer bed and breakfast offers suites with mountain views and a homemade, Bavarian-inspired breakfast. The Homer Airport is 5 miles away. Free Wi-Fi, a private entrance and an private bathroom is provided in each uniquely-decorated air-conditioned suite at Brigitte's Bavarian Bed und Breakfast. Handcrafted furniture, books and natural Alaskan décor are featured. A homemade breakfast with locally-sourced ingredients is served daily and may include smoked salmon, sourdough breads, waffles with local blueberries, fresh fruit salads, omelets with homegrown eggs and fresh chives, Swiss hash browns and Swiss muesli. Fresh coffee and peppermint tea are also provided. Special dietary requests can be accommodated with advance notice. The Homer Coast is 1 miles away. The Homer Spit is 9 miles away from Brigitte's Bavarian Bed und Breakfast.
Accommodation Dallas welcomes Brigitte's Bavarian Bed Und Breakfast, the ideal Homer AK Holiday outlet for all the family to enjoy. We have made sure that we have thought of everything you would expect from your vacation with many features, click on the email or phone now button to get in touch with the owner.Is Brigitte's Bavarian Bed Und Breakfast in Homer your property on Accommodation Dallas, please claim your listing and subscribe to update your contact details and receive your phone calls and emails from your clients.


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The Benefits of Vitamin E. Vitamins are good for our body inside and out. Today lets focus on vitamin E and all the good stuff that it can do for you! Do some of your skin concerns include: Stretch Marks, Dry Skin, or fine lines?
The Benefits of Vitamin E
Does anyone else have grandmothers or mothers who slather cold cream all over their face? Ever wondered why?
Chances are if you look at the little tub of cream one of the ingredients is vitamin E.
Studies show vitamin E can help slow down the production of fine lines due to it's thick texture and hydrating properties.
So keep this in mind. Dry skin — unhappy, tight, flaky, dull, and prone to showing more lines. Moisturized skin- happy, supple, plump, healthy, bright.
I would use this as a night cream because it really is rather heavy and who doesn't want to wake up to soft plump skin?
Now the stretch mark part is a little controversial. The studies go two different ways mentioning it really doesn't work and another saying if you use vitamin E combined with vitamin C whether it be in cream or pure form will actually help diminish the look of stretch marks.
The study that says it doesn't work means stretch marks will not completely disappear but rather the vitamin E improves the texture of skin making the stretch marks less noticeable.
So if you really think about it.
Vitamin E has a win-win situation
The jar I have says it can be used as a make-up base. I'm curious to see how that would work out. Maybe I need to try it and see if my makeup goes on smoother even though I already know my face will be a oily slick! I'll follow up and let you know those results! Try it out also if you go the route of Vitamin E Cream.
For those of you that use eye creams is Vitamin E or C included? What about those of you who have used lotions for stretch marks?
Wellness by Oriflame
The company Oriflame has products Wellness. These products contain all the essential vitamins and minerals. Vitamin E is contained in women's wellness and men's wellness. Sign up in Oriflame and order products Wellness discount.


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|25th March 2012, 20:47
Junior Member
Join Date: Mar 2012
Posts: 1
Shoutcast App Suggestion
Hi everyone, first off I just wanted to say hey as this is my first post on here
So I'm not sure if this is the right spot for this or not and if it's not I apologize in advance.
So my suggestion is simply this, to add an EQ with presets like your Winamp pro version for Android has. I absolutely love the shoutcast app on my iPhone but was saddened to discover that their was no EQ.
I was wondering if it is possible that you can add an EQ with the next version of the Shoutcast app for iPhone. I know for sure that I wouldn't be the only one that wouldn't mind paying for a pro version of some sort, maybe a .99c in app purchase even?. You could even remove the ads and make it 1.99 or something like that
Anyways I love the app and use it every day and the only thing that would make it better is an EQ.
Thanks for letting me have my input and I hope to see my feature suggestion added to the next version.
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TORONTO - Thursday, December 19, 2019, Judge Brian Weagant's Courtroom. How could everything go so bad? It should have been an easy "slam dunk" – a sentencing hearing to determine the level of "punishment".
Three young men, former disgraced and expelled students at a private school, St. Michael College School, charged with assault, sexual assault and sexual assault with a weapon on some of their fellow students, had already pleaded guilty.
One of them had taken the trouble to video the attacks and circulate them on social media – even going so far to "sell" access to this child pornography.
The parents of the victims had already launched a civil suit against the school, its Board and some Staff. Maybe they were unhappy at the slow pace of the police investigation, the judicial process… or simply "doing something" just to avoid collapsing into a mind-set favourable to vigilantism.
Justice Weagant's ruling was, to put it mildly, egregiously unhelpful: two years probation with seemingly no conditions. He couldn't even bring himself to reading the full sentence, claiming that the room was too noisy, and he did not want to be misunderstood.
Everyone else in the public marketplace understood:" bad boys" don't deserve punishment.
A female member of the Defense team went on talk radio to cry that these boys (and their families) have been su ering ever since the incident – she was talking about the [convicted] aggressors who had pleaded guilty on all charges.
They have trouble being accepted, no schools want them, she whined – so like the insensitive counsel to Marco Muzzo a few years ago who wanted sympathy and empathy for his client after he killed three young children and their grandfather with his car. There must be a set communications line all students from their Law School must learn as a condition of graduation.
Justice Weagant would seem to agree that it wasn't the fault of the students. Referring to pretrial psychological assessments of the culprits, he "concluded that the stage was set for these terrible events by existing school culture." Wow!
"This normalization of assaultive behaviour among the boys appears to have created an environment at the school, which provided the opportunity for even more concerning behaviours to take place," said Weagant.
Understand what he is saying in layman's terms. "Situation normal": Sta asleep at the switch; Coaches derelict in their social responsibilities; an indi erent Administration and Board; Uncontrolled Bullying… Boys raping other boys. One is tempted to say: "The man is an idiot". But he is a judge.
With such a sentence and broadbrush observation as justification he has also weakened the victims' case in Civil Court.
In other words, the victims and their parents bought into the culture at St. Mike's knowingly; they have only themselves to blame. Besides, it is Christmas.


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Monthly Archives: April 2015
Livia Grant's Having It All is now available!
Livia Grant's Having It All was released last week! This is the third book in the Passion Series which started with Wanting it All and was followed by Securing It All. Having It All shares Markus and Brianna's journey as they alter their vanilla relationship into a D/s relationship. They explore each other in a new way which makes their connection to each other stronger than before and we get to see the renewed excitement they have in each other after having worked past her infidelity and the secrets they were keeping from each other.
Along with witnessing this couple's changing dynamics, we also get fully involved in their best friends' budding relationship. Lukus and Tiffany have varying degrees of experience in BDSM. Lukus is a Master of Masters and Tiffany has only ever been to a few BDSM clubs and read lots of erotic books. After falling head over heels for each other, Lukus slowly introduces Tiffany to what she's been missing. As with any new relationship, they hit a few bumps along the way as they get to know each other, but the connection they develop is absolutely amazing.
Brianna and Tiffany are strong and independent women, yet they both realize they need something more. They both desire to be taken in hand and Markus and Lukus are just the men to give them what they want without changing who they are at their core. Each person learns how to change and bend for the one he or she loves and it is very exciting to watch as it happens. This book takes us along for the ride as they start enjoying having it all.
It's a little scary just how much I identify with Tiffany and the way she feels…her confusion, desire, wants, needs, fear of the unknown, fear of rejection, etc. I love following the development of all the characters – how they bend to each other as they begin to explore new their new relationship dynamics. Love is an amazing emotion and it really shines through in each of the characters as the story continues to play out. Needless to say, I cannot wait for the next book!
Congratulations, Livia, on another job well done! Thank you for creating a world that I love visiting time and again.
Don't shutdown and don't give up.
First, I want to thank everyone who has stopped by to leave a comment and provide support. Believe me, it helps and means a lot to know that you all are out there reading, sympathizing, and providing emotional and spiritual support where you can. I am not alone. We are not alone.
I'm still kind of at a loss as to what I want to share and talk about. I'll think about sitting down and starting a post, but I'll start to think about everything that happened before and what's going on now. Then, I'll decide I don't want to deal with thinking too much so I'll stop and won't even begin the post. I don't want to shutdown and honestly I don't feel like I am totally withdrawn because I am talking to Tom. I am asking questions about the past and trying to better understand what's happened. I am afraid of what we can't control about the future, but I have this sense of hope and I feel like everything will work out. If I didn't have that hope, then I think I would probably fall to pieces and not be able to function. I know that what we can control of the future looks pretty damn bright to me, so I want so desperately for things to just please work out. It doesn't even have to be the easiest way possible…all I am asking for is to find a road in the right direction.
I took Tom to the doctor last week so that we could get a recommendation on a counselor because I really believe that he needs to work through issues from childhood, grieve for his father, and find a way to cope with the rougher days of ADHD. Then, we can also focus on our relationship together.
This week, I'm trying to find out if Tom's medical insurance accepts the recommended counselor and set up the first appointment. So far, I think that this one may be out of network which means we might have to try someone else if we can't afford it.
Last night, Tom asked me why I haven't posted anything and wondered if I had given up on blogging. I told him I haven't given up but that I didn't know what to say or what to share. He knows that normally I would write about recent spankings, but I haven't done that in a while…not that there haven't been recent spankings around here. I got spanked for both my birthday on the 31st and his birthday on the 13th. I've also been spanked for fun and had few 3-lick consequences come my way. The desire to write is there, but the will and motivation to get started is not.
Yesterday, I really wanted a long, sound spanking but since I didn't know how I wanted it or for what reason I couldn't bring myself to tell him about it until we were cuddling after we had tried something new to me.
(NOTE: Anal play ahead…if it's not your cup o' tea, then skip the next four paragraphs.)
He said early on that he wanted to help give me something to write about, so he decided to pull out a few implements and our Ziploc bag of anal plugs of various sizes. This wasn't totally out of the ordinary and we have used the two smallest plugs before so I wasn't really worried. He started out spanking me while I pleasured him orally. It's strange how I used to hate giving blow jobs, but I actually do not mind giving Tom pleasure in that way and he certainly enjoys them.
As my level of sexual excitement increased, he picked up the lube and inserted the second to smallest plug. Since it didn't bother me at all, he switched it for the next size up which also slid in without much resistance. Because we hadn't tried this size before, he let me get used to it before pumping it in and out. He then asked if I was ready for the next one. I think on a normal day I probably would have told him no, but for some reason, I offered no resistance. I wanted to trust him completely again, so I let go of control. He picked up the largest one and very slowly eased it in place. This one felt a bit uncomfortable, but I was willing myself to get used to it and it helped when he admitted to me that he was actually smaller around than this one. He made me even more aroused by spanking me a few times as he played with it. Then, he pulled it out and slid a condom on while I grabbed my vibrator.
I placed the vibrator against my clit, put my ass in the air and laid my head on the bed. He lubed up and very gently eased his cock into my ass. I was rather surprised (and relieved, LOL) when his hips made contact with my butt. After a few moments, he started to slowly pull out and push back in. The sensations were definitely different. With the help of my vibrator, it didn't take long before I was close to an orgasm. Tom ramped up to a hard and fast pace and we were both thrown over the edge into orgasmic bliss.
It took us both a few minutes to recover and roll off the bed to clean up. He asked me what I thought about it and I said that I had enjoyed it, but definitely would not want to do it very often. It is still very much awkward, although I do like the smallest plugs.
When we got back into bed, I finally mentioned that I would like to get a longer spanking. I can't remember if I tried to explain it much, but after thinking about it more I believe I know what I'm looking for now. I'm wanting the intimacy of being over his knee. I want to be reassured as my bottom is warmed with his hand. I want to feel cherished as the leather kisses my cheeks. I want to cry and start letting go of the stress as the paddle smacks away the pain from the past. I want to feel relief and calm down as he holds me close because, after all we've been through, I am his.
I know I am asking a lot and I know everything won't magically be better, but it's a start.
Sorry, all. I realize this post seems very disjointed (or at least it does to me), but I'm glad to finally have a post put together enough to publish.
"You never know how strong you are until being strong is the only choice you have."
For two weeks, I have been stuck. I haven't known what to say or do. I wasn't sure if I wanted to share what was going on, but I've needed support and didn't know how to ask for it. My trust had been broken. I'm not talking about an affair or abuse. I'm talking about how someone else's choice of a coping mechanism turned into an addiction, into poor decisions, into taking risks that were never worth the possibility of losing everything.
I am and have been broken, terrified, sad, lost, angry, upset, hurt…and yet still a glimmer of hope exists. Belief that trust can be rebuilt exists. Love beyond measure still exists.
On March 24th, I had the rug pulled out from under my feet. I knew something wasn't right and hadn't been right for a while. Things between us had been going downhill fast since his dad passed away back in September. I couldn't figure out why. We started arguing more. He was spending less time with the kids that we were taking care of, so I had to step up with the cleaning, homework, food, etc. He was spending less time with me and more time with his brothers when they were here. He would be up all night with them. When they weren't here, he started working more and stay up late by himself. We started arguing more…about the kids, the money, and his brothers.
I never could place my finger on it. I just knew it got worse when other people were here. I tried to talk about it and explain to him what I saw or what I thought was happening, but it was easy to make excuses. He hadn't talked to his brothers in thirteen years. Their dad had just died. We had kids who weren't ours to raise. They are family.
…but in the mean time, we didn't invite my family down from 150-200 feet away. Why? Because my parents are nosy and I didn't want them to notice that anything was wrong. I didn't want them to judge Tom and his family too harshly. But, they were starting to notice things from afar. They could look down from their home and see that lights were on all through the night. They could see that the brothers were up a lot and sleeping at odd hours. Despite what I said, they could tell Tom was pulling away from me just from the amount he worked or the amount of time it looked like they were all awake at night.
On the 24th, he got his rude awakening – his wake up call. Right now, I hope beyond hope that we can overcome the legal issues that have arisen, in whatever way they turn out. Against all odds, I see a silver lining through my tears. I finally see the man I fell in love with again – the man I want to spend the rest of my life with. All this time, I was lost, but so was he.
We both know this cannot be fixed overnight. It took the course of six months to get to where we are. Six months of being kept in the dark, of secrets, and of lies. It is going to take a lot to earn back trust. I was hurt because I thought he was getting tired of me. I felt guilty because I thought I was being selfish. I was angry because I thought he wasn't listening. I felt like he was just pushing me away and I couldn't figure out why I was losing him.
Now, I worry that this might happen again. I feel guilty because I feel I could have done more to notice the signs earlier or prevent it from occurring. I'm angry because I feel like he let this happen. I feel like he took a risk and could have lost everything. Was it worth it? Was it worth the pain that I know he could see in my eyes? Was it worth allowing me to believe it was me?
Among my turmoil of emotions, I also feel an odd sense of strength. I feel vindicated that I knew something was wrong but wasn't sure what and that I had been right in knowing his judgement had been altered. I knew that it couldn't all be me. I know that I am not a selfish person.
For some reason, I feel it is worth to note what I was thinking the moment I got the phone call that yanked the rug out from under me. Stupid things crossed my mind…like "but my birthday is next week and yours is two weeks later, but we just bought the wedding ring, but we're supposed to get married in December, but I just paid the bill, but we haven't even had a vacation alone together, but we are finally alone again in our house, but what if I want to have a baby," and it goes on…right down to the question of, "was it worth it?"
I do believe addiction is a disease, but I also believe that you have an initial choice that you are in control of and what you choose is entirely up to you. What are you willing to risk, and ultimately, is it worth it?
Despite all that has happened, I have also experienced periods of being wonderfully happy again in the last two weeks. We've worked together putting flooring down in a house. We went on a picnic. We've watched movies together. I've even been spanked a few times for fun.
I do not want you to judge Tom because I have not shared everything with you. You do not know about his past or all of the circumstances. I do know about his past and I can sympathize with the situation because hindsight is 20/20. That does not mean I agree with everything that has happened, and I am certainly feeling all kinds of emotions that I need to deal with. He absolutely needed the rude awakening. He is ashamed and has regret for what he has put us through…what he has put me through. He is human and he made a mistake that snowballed out of control. He realizes he should have been honest from the beginning and has agreed to certain rules that we must live by in order for me to begin trusting again. We have to help each other through this because neither of us is ready to throw in the towel and walk away.
We have a long and difficult road ahead of us and unfortunately it will probably be peppered with events where we cannot be sure of the outcome nor how it will affect our future, but…we will try to do everything we can to make the best of it.


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According to South African news website News24, one of the key companies in the Guptas' crumbling business empire, broadliner Sahara Computers, has quietly closed down. The controversial family and their associates are now trying to sell Sahara's premises for €3.5m.
Sahara Computers and two of its sister companies in the IT sector – Annex Distribution and Sahara Systems – closed down several months ago, apparently without drawing much attention.
News24 on Friday gained access to Sahara Computers' abandoned premises in Midrand, Johannesburg. Sahara Systems was also housed in the same building. An estate agent from the estate agency whose sign is posted outside the building said that the property was in the market for €3.5m. Alternatively, the 6 500 sqm property could be leased for about €27 000 a month.
The property is owned by Islandsite Investments 180, the same property holding company that owns the Guptas' sprawling residential assets in the plush Johannesburg neighbourhood of Saxonwold. Islandsite's two remaining directors are Ashu Chawla and Ronica Ragavan, according to company records. Atul and Tony Gupta and their respective wifes, Arti and Chetali, had resigned as directors in 2016.


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