The present invention relates to a parallel with respect to the optical connection module for receiving an optical signal from the transmission optical fiber or an optical signal through an optical fiber. The present invention, by forming a reflective surface on the core end forming an optical waveguide light exact route change, and the focusing is to occur, and the attachment by embedding the light source / light detector in the trenches using a silicon optical bench, and a silicon optical bench surface an optical waveguide and to be attached to the light source / light detector and minimize the registration error between the optical waveguide and then sorted manually mark, to ensure that the alignment error between the optical waveguide and the light source / light detector minimized by the optical waveguide inserted into the ferrule so as to be fixed to the adapter the coupling loss is minimized in the process in which the optical signal passes the optical output is increased, to facilitate the optical coupling by manual alignment and provides a parallel optical link module that can achieve an optical connection at a low cost and excellent productivity.


The article provides a philological analysis of prose by K.D. Vorobyov. The author used the following methods in this work: slow reading, line-by-line analysis, analysis of key points, linguistic commentary and immanent analysis. The study revealed that the narration in the story under consideration is of a markedly subjective nature, which is associated with various figurative shifts caused by modal and semantic variability of the text. In this connection, the line between the main character and the author of the story becomes blurred; the narrator's «I» splits; various temporal and spatial planes shift and transform; and perspectives are combined and dispersed. Most of the depicted events are presented from the characters' perspective, thus making the reader feel part of the narrated world. In addition, the perfected technique of subjectifying narration in Vorobyev's work takes on a style-forming, expressive, as well as a conceptual function.


The invention discloses a Chinese herbal medicine compound preparation for treating congestive heart failure and a preparation method thereof. The Chinese herbal medicine compound preparation comprises various components according to the parts by weight: 10-30 parts of ginseng, 10-30 parts of the root of red-rooted salvia, 10-30 parts of safflower, 10-30 parts of rhizoma cyperi, 10-30 parts of bighead atractylodes rhizome, 10-30 parts of angelica, 10-30 parts of peach kernel, 10-30 parts of red paeonia, 10-30 parts of schisandra chinensis, 10-30 parts of pseudo-ginseng, 10-30 parts of cinnamon, 10-15 parts of monkshood, 10-30 parts of ophiopogon root, 10-30 parts of milk weteh, 10-30 parts of asarum, 10-30 parts of notopterygium root, 10-30 parts of spatholobus stem, 10-30 parts of rhizoma atractylodis, 10-15 parts of toad coat, 10-30 parts of folium ginkgo, and 10-30 parts of the rhizome of chuanxiong. The Chinese herbal medicine compound preparation can inhibit platelet aggregation and thrombosis, improves microcirculation, increases coronary blood flow, has the function of cardiac stimulant, can increase cardiac and cardiac index, has the efficacy of dilating blood vessels and depressurization, and can be effectively used for treating patients with clinical congestive heart failure.


Cosmological perturbation theory is known to converge poorly for predicting the spherical collapse and void evolution of collisionless matter. Using the exact parametric solution as a testing ground, we develop two asymptotic methods in spherical symmetry that resolve the gravitational evolution to much higher accuracy than Lagrangian perturbation theory (LPT), which is the current gold standard in the literature. One of the methods selects a stable fixed-point solution of the renormalization-group flow equation, thereby predicting already at the leading order the critical exponent of the phase transition to collapsed structures. The other method completes the truncated LPT series far into the UV regime, by adding a non-analytic term that captures the critical nature of the gravitational collapse. We find that the UV method most accurately resolves the evolution of the nonlinear density as well as its one-point probability distribution function. Similarly accurate predictions are achieved with the renormalization-group method, especially when paired with Pad\'e approximants. Further, our results yield new, very accurate, formulas to relate linear and nonlinear density contrasts. Finally, we chart possible ways on how to adapt our methods to the case of cosmological random field initial conditions.


The distribution of slopes on the six basaltic shield volcanoes in the Western Galapagos Islands is investigated using a digital elevation model derived from airborne interferometric radar (TOPSAR) data. These measurements have a spatial sampling of 10 m/pixel, a vertical accuracy of 3 to 5 m, and constitute the highest resolution, most complete, topographic data set available for the islands. Volcano heights are determined to range from 1,124 m (Sierra Negra) to 1,710 m (Wolf). Over extensive areas of each volcano, slopes exceed 25°, with the highest slopes being ∼37° on Wolf and ∼36° on Fernandina. We confirm that two morphologic subgroups exist: Cerro Azul, Fernandina, and Wolf, with deep calderas (depth between 40–60% of the subaerial height of the volcano) and steep (>20°) maximum slopes at elevations between ∼60 and 80% of the volcano height; and Alcedo, Darwin, and Sierra Negra, with shallow calderas (depth <25% of subaerial height) and slopes that remain <15° until ∼90% of the total height is reached. Our data show that steep slopes are not uniquely correlated with the occurrence of arcuate fissures at the summit, leaving the origin of the steep slopes unresolved.


We discuss the knowledge expression, reasoning and probability computing in causality diagram, which is developed from the belief network and overcomes some shortages. The model of causality diagram used for system fault diagnosis is brought forward, and the model constructing method and reasoning algorithm are also presented. At last, an application example in the fault diagnosis of the nuclear power plant is given which shows that the method is effect.


A method for heat dissipation module power dissipation of the heating elements comprising a heat exchange element having a closed inner lumen, the inner lumen is provided with a powder sintering and the working fluid portion, the outer portion having a flat heat generating element and disposed a fixed structure; and a non-finned heat dissipation module having a central bore portion of said heat-fixing of the structure, and at least one air passage is provided around the central hole, the heat generated by the heat generating element by the membership mounted through switching element to a non-finned heat transfer module, capable of generating air flow in said air passage through a chimney effect, and thus quickly emit heat generated by the heating element. Compared to conventional thermal module, without the use of a fan, the present invention can be directly applied to the heat generating element more than 100W, it is especially suitable for high power dissipation of the heat generating element.


: The article examines the peculiarities of the formation of the ecological and economic security system and the specifics of its principles. The relevance of the transformation of approaches to understanding the essence and principles of ecological and economic security in the context of the need to ensure sustainable development is substantiated. The levels of ecological and economic security and the peculiarities of changes in profits and costs during the transition of the economic system and business entities between these levels are determined. The principles of implementation and formation of economic tools for ensuring environmental safety are proposed.


This paper analyses the subject of globalisation in the context of economic security looking at for and against arguments, and asks whether or not Maldives has benefitted from globalisation, and highlights the issue of economic security for Maldives as a nation.


Organic solvents have been used for hundreds of years in virtually all types of paints and coatings. Although waterborne and other alternative coating technologies have begun to replace solvent-based coatings in certain applications, solvent-based coatings are still used in the vast majority of coating operations. Most organic solvents are volatile organic compounds (V O C s) and can react photochemically in the atmosphere to form ground-level ozone. As a result, policy makers have encouraged-and in some cases required.-the use of low-or no-VOC coatings. This paper points out that VOC content should be only one of the factors considered by users, formulators, and regulators when evaluating alternative coating systems. In some cases, there is no appreciable environmental benefit to be gained from reducing solvent emissions. Recent reports by the Nationa4 Academy of Sciences and by the U.S. Environmental Protection Agency have shown that, in areas where there are relatively low levels of nitrogen oxides (NO,), reducing VOC emissions will have little or no effect on reducing ground-level ozone. In addition, regulatory or voluntary programs to control voc emissions from coatings should take seasonal and temperature differences into account. Because of the atmospheric chemistry of ozone formation, there is little or nothing to be gained from using low-VOC coatings during the winter months or in the cooler parts of the country. Moreover, the ozone-formation potential of different VOCs varies depending on their photochemical reactivity. Therefore, where VOC-control efforts are justified, they should focus on VOCs with the highest photochemical reactivity. Coating users and formulators, as well as regulators, should also consider performance tradeoffs when evaluating low-or no-VOC coating technologies. For technical reasons, alternative coating technologies are difficult or impossible to use under certain circumstances. For example, water-based technologies may not be feasible in areas with high relative humidity or desirable for applications involving frequent touch-up. The use of low-VOC coatings may also involve significant environmental. tradeoffs. In many cases, for example, water-based coatings generate increased levels of liquid and solid wastes. In addition, because water has a'very high heat of vaporization, water-based systems often require much more energy usage than solvent-based systems. Life Cycle Assessment (LCA) is a useful analytical tool for comparing the environmental tradeoffs associated with the use of alternative coating technologies, Two recent studies using LCA have shown that water-based systems are not necessarily environmentally beneficial when compared to traditional solvent-based systems. Because no coating technology is always environmentally …


ABSTRACT Geoengineering, the idea of addressing climate change through large-scale technological projects, is a unique example of a contested emerging technology. It stands out in the degree to which both its scope of possibilities and its premise are characterized by global existential risks. Despite controversy due to inherent and perceived risks, this field has been shifting toward mainstream consideration. Geoengineering science policy reports reflect this shift and influence the subsequent trajectory of research and potential deployment. The two most notable geoengineering policy reports are those by the Royal Society in 2009 and the National Research Council (NRC) in 2015. Discursive strategies recurrent in these reports construct notions of legitimacy and normalcy in regard to geoengineering. These strategies include relative legitimation of actors and approaches, differentiating research from deployment, elevating particular geoengineering methods through comparative evaluation, and normalizing novel geoengineering proposals through analogy. These strategies are present in both the benchmark geoengineering policy reports, with a deepening and entrenchment evident in the later NRC report. Together, these discursive strategies promote the legitimization of geoengineering research.


Objective To explore the clinical application and value of multidetector CT(MDCT)curved planar reformations(CPR)in diagnosis of intestinal diseases.Methods Thin slice scans were used to acquire images on 49 patients of intestinal diseases,and CPR technique was used to reconstruct the images along the direction of intestine.The surgery and pathology were regarded as gold standard.Results The successful rate of CPR technique was 100%.CPR could show the intestinal diseases clearly.The accuracy of CPR on localizing diagnosis was 100%,the accuracy of qualitative diagnosis was 91.8%(45/49).Conclusion CPR can directly display intestinal diseases.CPR is an efficient supplement to CT axial images and multiplanar reconstruction(MPR)images,has satisfactory diagnostic effect and application value.


A primitive neuroectodermal tumor of peripheral nerve origin was examined by light and electron microscopy. The lesion arose in association with the SI nerve root of the lumbosacral plexus in a 22‐year‐old female. Following a surgical biopsy, the patient received systemic chemotherapy; however, approximately one‐and‐a‐half years later, she suffered a clinical relapse with locally recurrent tumor. An excisional biopsy was performed, and pathologic examination revealed progressive neuroblastic differentiation. The ultrastructural features of neoplastic Homer‐Wright rosettes will be illustrated, and the non‐specificity of cytoplasmic glycogen in the evaluation of "small round cell neoplasms" will be emphasized.


Ag3CuS2 is comprehensively studied by applying synchrotron and neutron powder diffraction as well as thermal analysis in the range from 2 K up to the melting point around 960 K. The unique sequence of the reversible phase transitions P- was detected prior to the sample's melting. The transitions at 110, 387 and 483–549 K are found to be of first order, whereas the transition at 250 K is a second-order one. The major change in the structure of jalpaite resulting from the phase transition is a modification in the coordination geometry of the silver atoms. A large degree of structural disorder is stated for - and -structured Ag3CuS2, which correlates with the high ionic conductivity within both cubic polymorphs. The thermal expansion of jalpaite shows some unusual features, i.e. a negative expansion along the c-direction in the I41/amd phase, a nonlinear expansion within the polymorph and an expansion increase upon entering the mixed region. Low-temperature specific heat data confirm first- and second-order anomalies at 110 and 250 K, respectively, and illustrate a pronounced non-Debye-like behaviour of jalpaite.


Influence of deep freezing on the basic physical and chemical characteristics of wines dining rooms white and red wines isinvestigated: ethyl alcohol content, titrable acidity, phenolic compounds, organic acids, aromatic components, cationiccompounds of metals. It includes data of ice composition which was extracted after freeze process.


Paper is in Turkish, SSRN doesn't allow uploading for Turkish characters. Please see the attached pdf file for its content.


While MnO2 is a promising material for pseudocapacitor applications due to its high specific capacity and low cost, MnO2 electrodes suffer from their low electrical and ionic conductivities. In this article, we report a structure where MnO2 nanoflowers were conformally electrodepositedontocarbonnanotube(CNT)-enabledconductivetextile fibers.Suchnanostructures effectively decrease the ion diffusion and charge transport resistance in the electrode. For a given arealmassloading,thethicknessofMnO2onconductivetextile fibersismuchsmallerthanthatona flat metal substrate. Such a porous structure also allows a large mass loading, up to 8.3 mg/cm 2 , which leads to a high areal capacitance of 2.8 F/cm 2 at a scan rate of 0.05 mV/s. Full cells were demonstrated, where the MnO2� CNTtextile was used as a positive electrode, reduced MnO2� CNTtextile as a negative electrode, and 0.5 M Na2SO4 in water as the electrolyte. The resulting pseudocapacitor shows promising results as a low-cost energy storage solution and an attractive wearable power.


The objective of the current thesis is to investigate the effects of the different process in Wire cut EDM process parameters on the surface quality, maximum material removal rates and obtain the optimal sets of process parameters so that the quality and MRR of machined parts can be optimized. Experiments are conducted on the composite material (Al 6061 (90.5%) + SCi (7.5%) + Graphite (2%)) pieces by varying parameters. The process parameters varied and their respective values are Pulse Time on - 100µsec, 150 µsec, 200µsec & Pulse Time off – 52µsec, 56µsec, 60µsec, Servo Voltage – 30V, 50V, 70V and Wire Feed – 2mm/min, 3mm/min, 4mm/min. Other parameters are kept constant such as Wire diameter - 0.3mm, Peak Current – 1.1Amp, Coolant is Distilled water, Wire Tension – 7Kgf. The optimization is done by using Taguchi technique considering L09 orthogonal array. Optimization is done in Minitab software.


A copper-catalyzed condensation—α-arylation cascade reaction of o-halobenzaldehydes (I) with glycine methyl ester (II) provides access towards title isoindolecarboxylates (III) in good yields.


A nonregenerative optical transmission experiment with a chromatic dispersion of more than 10000 ps/nm is reported. Externally intensity-modulated 2.4 Gb/s optical signals were transmitted over 710 km of nondispersion-shifted optical fiber using ten Er-doped fiber amplifiers with a total net optical gain of 125 dB. Although the total chromatic dispersion amounted to 12300 ps/nm, the power penalty observed was as small as 0.5 dB, and an error floor was not observed. The effect of transmitter phase noise associated with fiber chromatic dispersion was experimentally investigated.<<ETX>>


ABSTRACT The ion-exchange kinetics of Az+sol ⇆ Na+mem (Az+ = Cs+/Ba2+/Eu3+) in Nafion-117 have been measured using non-stationary radiotracer technique for trace concentrations of Az+ ions in external solution. A method based on non-steady state Nernst–Planck approach has been developed and used to fit the experimental ion-exchange profiles to obtain the diffusion coefficients (DCs) of these ions. The DCs, thus obtained, have been found to be appreciably lower than the literature-reported self-diffusion coefficients, indicating slower rate of ion-exchange. The results show that membrane DCs of these ions are modified by bulk electrolyte solution.


To investigate the perception of the correlation between systemic diseases and oral health among some university students. The questionnaires were conducted on 485 students from 3 universities in Gwangju. As a result of the study, the female was higher than the male and was the highest in the fourth grade. Subjective health status, drinking status, smoking experience, and exercise were not significantly different in recognizing the association between systemic disease and oral health. The group with experience in oral health education recognized 3.18, and the group that practiced educational contents was highly recognized as 3.21. There was a significant difference between the two groups. Multiple regression analysis showed that major factor and grade factor influenced the perception of association between systemic disease and oral health. Therefore, it is necessary for university students to recognize the importance and necessity of periodical oral examinations. It is thought that the incidence of disease should be strengthened and enforced to recognize that there is a correlation with various diseases.


This chapter describes the direct torque control (DTC) technique for permanent magnet synchronous motors/machines (PMSMs). The DTC technique has evolved much since mid-1980s when a less complex, cheaper and potentially faster method of torque and flux control than the pre-existing rotor flux-oriented vector control (RFOCNC) for induction machines first emerged. The DTC technique is based on closed-loop regulation of torque and stator flux linkage obtained from estimators using voltage vectors and currents in the stator reference frame and the machine model. Drive dynamics under DTC control is as fast and can be faster than that under RFOCNC in which rotor position sensing is used for exercising control in the rotor reference frame. This chapter starts with a brief review of the context of these developments, including the underlying theory (which had existed prior) and methods that have been used to apply DTC to PMSMs. Some comparative evaluations are included that may help researchers and engineers to further develop the method and apply it to high-performance PMSM drives in various applications.


This paper is concerning switching impulse air gap insulation characteristics of rod-to-plane and V-string 6-conductor bundle to tower body in ±800 kV transmission lines.The tests were performed in China Southern Power Grid Co.,Ltd.(CSG) Kunming outdoor UHV laboratory at an altitude of 2 100 m.The switching impulse strength performance were obtained at a rod-to-plane arrangement and a full-scale model of 6-conductor bundle to tower.The test gap length of the typical rod-to-plane arrangement is 1.5~10 m and 5.3~8.2 m for the conductor-tower model,and the range of test voltage is about 450~3 100 kV.The critical positive switching impulse strength of conductor-tower gap is 1 525 kV in the gap length of 6.2 m.Additionally,the influence of the wave front time(100~1 700 μs) on the 50% flashover voltage is discussed.According to the test data,the minimum air gap clearances of the conductor-tower model with V-insulators at the altitude of 2 100 m should be longer than 6.8 m(wave front time 250 μs) and 5.8 m(wave front time 1 000 μs),respectively.The results are useful to air gap insulation design in UHVDC systems with rated voltage of ±800 kV.


This project reads and controls the temperature and humidity of animal shelter and shatters away snakes from the animal shelter. The temperature and humidity will be first measured and then according to the favorable conditions for the animals the temperature and the humidity will be changed. An ultrasonic generator will be used to replicate away snakes by generating an ultrasonic frequency of 50 Hz.
 By doing this project we provide a safe and healthy environment for domestic animals by maintaining shelter's temperature and protecting them for animals.


A Pahlavi text entitled Ayadgar i Zareran (AZ) relates the legendary battle between Vistasp, Kayanian king, and Arjasp, king of Xyons. § § 17-21 of AZ describe the answer made by Zarer, Vistasp's brother, to Arjasp's demand that Vistasp should abandon Zoroastrianism. A new translation of AZ § § 17-21 is given here to elucidate the latent eschatology of Zoroastrianism in the answer full of metaphor. The latter half of the answer should be interpreted as follows: … Next month we, except you, shall (live in the peaceful world just as all the people) drink "immortality" (on the Last Day and live for ever); there, at Hutos-wood and the meadow (morv: Pth marγ) of Zardust, not a high mountain nor a deep lake, on that level plain (just as gods are separated from demons on the Last Day, our) horses and brave footmen should be separated (from you for ever). Come from there so that we shall come from here. And you will see us and we shall see you. And we shall show you how (you will be struck by us just as) demons are struck at the hands of the gods (in the Last Day Battle).


Intracellular replication of Brucella requires the VirB complex, which is highly similar to conjugative DNA transfer systems. In this study, we show that Brucella internalizes into macrophages by swimming on the cell surface with generalized membrane ruffling for several minutes, after which the bacteria are enclosed by macropinosomes. Lipid raft‐associated molecules such as glycosylphosphatidylinositol (GPI)‐anchored proteins, GM1 gangliosides and cholesterol were selectively incorporated into macropinosomes containing Brucella. In contrast, lysosomal glycoprotein LAMP‐1 and host cell transmembrane protein CD44 were excluded from the macropinosomes. Removing GPI‐anchored proteins from the macrophage surface and cholesterol sequestration markedly inhibited the VirB‐dependent macropinocytosis and intracellular replication. Our results suggest that the entry route of Brucella into the macrophage determines the intracellular fate of the bacteria that is modulated by lipid raft microdomains.


A 27-year-old man with widespread lymphadenopathy had multiple sites of accumulation on Ga-67 imaging. The diagnosis of sarcoidosis was confirmed by biopsy. In addition to Ga-67 uptake in intrathoracic lymphadenopathy, Ga-67 was seen at multiple extrapulmonary sites of sarcoidosis.


textabstractAdequate and serial functional cardiovascular assessment is important in
patients with congenital heart disease because many show disruption of
normal myocardial geometry, which may or may not be accompanied with
hemodynamic overload. We now know, that even after so-called "corrective
surgery", total cure is only seldomly achieved. The presence of residual
cardiac abnormalities may lead to malignant myocardial remodeling, which
eventually may result in heart failure.


The previous reported plant defensin gene amino acid sequences were performed using blast similar alignment program on Brassica rapa database to predict the candidate defensin gene in Brassica rapa genome by bioinformatic methods,the conserved domain of defensin gene has also been confirmed.We analyzed the variation of upstream region,promoter region,exon region,intron region and UTR region during the evolution process.In addition,the variation of expression pattern as well as cis-regulate element have been analyzed in this paper.The results demonstrated that defensin genes encoding 60-80 amino acid short peptides and each has eight conserved cysteine residues.The major function domain of defensin genes maintain relative stable,signal peptide sequences have been diverged in partial members.The length of intron has three variation patterns that were increase,contraction and disappear respectively.The nucleotide variations in promoter region were remarkable which compare to other regions.The cis-regulate element mainly involved in light response element,defensin response and signal molecule response element.The prediction of the expression pattern may diverge in the process of evolution such as gene silencing and selective expression differences.


In this work, LiNixCo1-xO2 (x=0~1.0) films were deposited by RF magnetron sputtering. First, the effect of various sputtering parameters (such as working pressure, O2 fraction, and rf power) on the film growth rate and film composition of HT-LiCoO2 deposited on Pt-coated silicon were investigated. The effect of annealing temperature and annealing time on crystallinity and electrochemical properties of HT-LiCoO2 films were also discussed. Second, LiNixCo1-xO2 (x=0.5) films were deposited on Pt-coated silicon. The structure and composition were investigated. Consequently, the effect of annealing process on crystallinity and electrochemical properties of LiNixCo1-xO2 (x=0.5) films were illustrated. The results indicated that film growth rate of HT-LiCoO2 was obviously enhanced by the decreasing pressure, decreasing O2 fraction, and increasing RF power. However, it also resulted in high compress stress and film peeling. In addition, the Li/Co ratio of HT-LiCoO2 film initially increased with the inceeasing pressure, increasing O2 fraction, and increasing RF power but finally decreased at higher pressure, O2 fraction, and RF power. The as-deposited films and annealed films show crystalline HT-LiCoO2 single phase with (104) preferred orientation under various sputtering parameters. From ICP-MS results, it was observed that the sputtering parameters and annealing process affected the compositions of the films significatly. The annealing process enhanced the crystallinity of HT-LiCoO2 films. The CV curve shows three well-defined redox peaks. The LiCoO2 films deposited by RF sputtering were electrochemically active. The 1st discharge capacity of 500oC, 600oC, and 700oC-annealed LiCoO2 thin films was about 41.77, 50.62, and 61.16 Ahcm-2m-1, respectively. The 50th discharge capacity remained 58.1%, 72.2%, and 74.9% of the 1st discharge capacity for LiCoO2 films annealed at 500oC, 600oC, and 700oC, respectively. Films showed difference in crystallinity and resulted in the variation of Li+ diffusion coefficient that was measured and estimated by slow-scan-rate cyclic voltammetry (SSCV). The charge/discharge tests indicated that films that exhibit higher DLi+ showed better rate capability. LiNixCo1-xO2 (x=0~1.0) thin-film cathodes were grown on Pt-coated silicon substrate by RF sputtering. From XRD, TEM, and Raman spectra analyses, the structure of the 250oC as-deposited LiNixCo1-xO2 (x=0~1.0) films exhibited layered (R-3m symmetry) crystalline structure with (104) out-of-plane texture. From XRD and Raman spectra analyses, the crystallinity of the as-deposited films was enhanced by postannealing due to the rearrangement of atoms during the annealing process. The stoichiometry of LiNixCo1-xO2 (x=0.5) film was Li1.29Ni0.49Co0.51O2, the content of Li in film decreased with the increasing annealing temperature. The Li+ diffusion coefficient and discharge capacity of the LiNixCo1-xO2 (x=0.5) thin-film cathode were direct proportion to the annealing temperature. The 1st discharge capacities of 500, 600, and 700oC-annealed films were 42.95, 51.20, and 60.07 μAh•μm-1•cm-2, respectively. The 50th discharge capacity remained 60.6, 65.4, and 68.6% of the initial discharge capacity. Annealed films showed difference in crystallinity and resulted in the variation of Li+ diffusion coefficient that was measured and estimated by slow-scan-rate cyclic voltammetry (SSCV). The charge/discharge tests indicated that films exhibit higher DLi+ showed better rate capability. The electrochemical properties of LiNixCo1-xO2 (x=0.5) films are close to that of HT-LiCoO2 films under the same discharge condition. Based on the motive for decreasing the cost of material synthesis, LiNixCo1-xO2 (x=0.5) exhibits practical interest to substitute for commercial cathode material- HT-LiCoO2.


This paper describes the design and implementation of the remote monitoring system of the communication power supply based on Modem.The system includes secondary structure,and is composed of foregrounding(monitoring station) and background(monitoring center).The foregrounding hardware is based on 8031,and software is based on C51 language,the monitoring center software is based on Visual C++ language.By actual application,it has many advantages such as good reliability,easy operation,and can do the real-time remote monitoring of multiple communication power supply stations.


Since entering the 21st century,with the change of the history culture,the contemporary Chinese aesthetics has also entered in a new history time.Such condition wants us while studying the contemporary Chinese aesthetic,to have three kinds of fundamental consciousness,they are: context consciousness;native consciousness and practical consciousness.


The agenesis ot the frontal lobes described by Bateman is probably indistinguishable from contraction consequent upon diffuse glial sclerosis and, IIltiologically, the responsible mechanism could be protracted ischlllmia and anoxia giving rise to focal or diffuse glial overgrowth, glial infiltration and dense, pseudo-gliomatous gliosis. Some of the expressions of the glial reaction may take the form of a relative or absolute expansion of the surfaces of the involved lobe, but for the most part the epileptic brain will appear atrophic with the gyri fiattened and small, or the appearance will be somewhere between this and normal. The arteries demonstrated at cerebral angiography are, of course, almost entirely superficial to the lobes of the hemispheres, and few deep arteries are normally seen. Arteries will, as a rule, run in the sulci, but they will often leave a given sulcus to pass over the gyrus and enter the adjacent sulcus; in this way the variable looping or tortuosity of the anterior and middle cerebral arteries is explained. As sulcal depth and separation are reduced in the presence of such lesions as tumours, obstructive hydrocephalus or cerebritis, the related vasculature coursing over the brain surface will lose sinuosity and appear stretched.


This invention is directed to a method of enhancing or facilitating the clearance of the lung mucus secretions in a subject. This invention is also directed to a method of facilitating the hydration of the lung mucus secretions in a subject. This invention is further directed to a method of preventing or treating diseases or conditions associated with impaired lung or airway function in a human or other mammal. The method comprises administering to a subject a pharmaceutical composition comprising a therapeutic effective amount of P2Y6 receptor agonist compound, wherein said amount is effective to activate the P2Y6 receptors on the luminal surface of lung epithelia. The P2Y6 receptor agonist compounds useful for this invention include mononucleoside 5'-diphosphates, dinucleoside monophosphate, dinucleoside diphosphates, or dinucleoside triphosphates of general Formula (I), or salts, solvates, hydrates thereof.


Making clear about the directrs′right duty and responsibility is of great importance for the board of directors to play its part properly and for maintaining the overall interests of the corporation.But our current″Firm Law″bears many inadequate definitions leaving a room for further standardization and perfection.The essay supplies an exploration on the directors′right and its controling and on the perfection of the disposition of right duty and responsibility


Salami, A. L., & Ahmed, E. (2014). Study of the Relationship between Transformational Leadership, Organizational Culture, Followers' Creativity, Organizational Learning, and Organizational Innovation: Evidence from the United Arab Emirates (Doctoral dissertation).


: Parental attachment refers to the protective and comforting role of parents toward their children. This role has been violated in cases of maltreatment. Understanding the attachment of parents who endanger their children can illuminate the psychological processes behind the harmful behaviour of parents. This paper proposes assessing parental attachment with the Adult Attachment Interview (AAI, George, Kaplan and Main, 1984, 1996), classified according to the Dynamic-Maturational Model of Attachment and Adaptation (DMM, Crittenden & Landini, 2011). We discuss meta-analyses of the 'gold standard' Berkeley method (Main & Goldwyn, 1984; 1989; Main et al., 2003) for extracting AAI information. AAIs of maltreating adults classified with the Berkeley method have an improbably high rate of secure attachment, making it inadequate for family forensic applications. In contrast, the DMM uses a


A new two-stage plasma accelerator was tested to conduct the hypervelocity acceleration of microprojectiles. The accelerator consisted of a gas gun as the first stage and a plasma accelerator as the second stage. It was confirmed that the two-stage operation performed well at any timing started by the laser trigger system. It was found that the velocity of projectiles was increased in the two-stage operation and that the velocity greatly depended on the position at the beginning of acceleration. The impact rate of projectiles on a target was also markedly increased.


Recent works unraveled an intriguing finite-time dynamical phase transition in the thermal relaxation of the mean field Curie-Weiss model. The phase transition reflects a sudden switch in the dynamics. Its existence in systems with a finite range of interaction, however, remained unclear. Here we demonstrate the dynamical phase transition for nearest-neighbor Ising systems on the square and Bethe lattices through extensive computer simulations and by analytical results. Combining large-deviation techniques and Bethe-Guggenheim theory we prove the existence of the dynamical phase transition for arbitrary quenches, including those within the two-phase region. Strikingly, for any given initial condition we prove and explain the existence of non-trivial speed limits for the dynamical phase transition and the relaxation of magnetization, which are fully corroborated by simulations of the microscopic Ising model but are absent in the mean field setting. Pair correlations, which are neglected in mean field theory and trivial in the Curie-Weiss model, account for kinetic constraints due to frustrated local configurations that give rise to a global speed limit.


Temperature dependence of dielectric constants of Pb 3 (VO 4 ) 2 was experimentally reexamined under several pressures. No indication was found for the divergence in dielectric constant related to the direct transition from the R\=3m phase to the A2 phase, confirming the validity of previously reported data of dielectric constant. This feature of dielectric constants remains puzzling.


This paper describes altitude ignition experiment results for a scaled hydrogen-fueled turbojet engine model applied for Balloon-Based Operational Vehicle in-flight testing. Although hydrogen has remarkable combustion characteristics among the combustion fuels, at low pressures, the hydrogen-fueled combustor showed difficulty in the originally planned altitude ignition conditions. The follow-up step-by-step refinement of the ignition sequence is explained using experimental data. A similar situation might occur for future hydrogenfueled High Altitude Long Endurance (HALE) flights. These limited but still wide combustion capabilities of the hydrogen fuel might facilitate the introduction of gas-turbine power plants in the HALE flights.


This paper studies workers' occupational switching behavior and how lifetime earnings inequality is affected by the match between workers' ability and the skills required by their occupation. Using Armed Services Vocational Aptitude Battery (ASVAB), O*NET, and National Longitudinal Survey of Youth 1979 (NLSY79), we create empirical measures of the match quality between each worker's ability and the skills emphasized by his/her occupation, and analyze their effects on workers' labor market outcomes. We find that low match quality---what we also call 'skill mismatch'---between one's skills and required occupational skills reduces wage growth during an occupational tenure. Furthermore there is a persistence across occupations: match quality in occupations held early in life has a strong effect on wages in future occupations. We view these findings within the context of a general equilibrium model of occupational choice and human capital accumulation. We believe that our study sheds light on the importance of (i) occupational match on determination of wages, and (ii) workers' learning on their ability and the skills required by occupations.


Purpose – The purpose of this paper is to explore the possibilities of workplace democracy in contemporary organisations. While organisational democracy is a popular theme in contemporary management literature, it is often asserted that participatory democracy is impractical and thus representative forms of governance constitute a more appealing and "realistic" option. Such views not only fail to picture workplace democracy beyond procedural principles (e.g. periodical elections), but they also block one of its promising features: its openness to change. In this context, direct democracy that is guided by horizontality and prefiguration may offer more promising grounds in the search for workplace democracy.Design/methodology/approach – The paper exposes the contradictions and limits of representative democracy and traces the debates around hierarchism and horizontality, size and democracy with the aim to focus on its core theme – workplace democracy.Findings – This paper argues that although representativ...


We present a method for real-time person tracking and coarse pose estimation in a smart room using a sparse array of single pixel time-of flight (ToF) sensors mounted in the ceiling of the room. The single pixel sensors are relatively inexpensive compared to commercial ToF cameras and are privacy preserving in that they only return the range to a small set of hit points. The tracking algorithm includes higher level logic about how people move and interact in a room and makes estimates about the locations of people even in the absence of direct measurements. A maximum likelihood classifier based on features extracted from the time series of ToF measurements is used for robust pose classification into sitting, standing and walking states. We use both computer simulation and real-world experiments to show that the algorithms are capable of robust person tracking and pose estimation even with a sensor spacing of 60 cm (i.e., 1 sensor per ceiling tile).


This review article provides brief information on rehabilitation measures that improve the local and general condition of patients with jaw fractures. In the recent year the number of injuries with maxillofacial trauma has significantly increased in all countries of the world. Among maxillofacial injuries, fractures of the jaws occupy the main place (65- 80%), and most of the patients are young and able-bodied people. Despite the continuous improvement of the treatment methods of jaw fractures, the periods of immobilization and temporary disability are not reduced, and the incidence of inflammatory complications remains high, which significantly worsens the outcome of trauma. This largely depends on the lack of an effective system of rehabilitation of patients and a comprehensive approach to treatment with the use of both, pharmacological, psychotherapeutic, and physical rehabilitation measures. Complex treatment and rehabilitation of patients with jaw fractures will promote rapid stabilization and reduction of posttraumatic manifestations of the disease and, as a result, improve physical and mental health and increase the life potential and the level of their working capacity. The object of the review is to study and combine rehabilitation activities, that improve the health, working capacity and local status of patients with jaw fractures during immobilization and after removal of splints. Materials: The articles were identified using the computerized search engine PubMed, Elsevier, Cochrane Central, Google scholar, Google search, Research Gate, Ebsco Host, dissercat.com, medical-diss. com, cyberleninka.ru and other possible sites with keywords such as maxillofacial trauma, mandibular fracture, jaw fracture intermaxillar fixation and rehabilitation, recovery, physiotherapy, psychology, nutrition, feeding, diet, care, therapeutic gymnastics and in various combinations of these words in Russian and English. And they also took into account the relevant bibliographic lists. Randomized controlled trials, meta-analyzes, prospective clinical trials were selected based on their significance.


Much of the industrial electrical generation capability being added worldwide is gas-turbine engine based and is fueled by natural gas. These gas-turbine engines use lean premixed (LP) combustion to meet the strict NO{sub x} emission standards, while maintaining acceptable levels of CO. In conventional, diffusion flame gas turbine combustors, large amount of NO{sub x} forms in the hot stoichiometric zones via the Zeldovich (thermal) mechanism. Hence, lean premixed combustors are rapidly becoming the norm, since they are specifically designed to avoid these hot stoichiometric zones and the associated thermal NO{sub x}. However, considerable research and development are still required to reduce the NO{sub x} levels (25-40 ppmvd adjusted to 15% O{sub 2} with the current technology), to the projected goal of under 10 ppmvd by the turn of the century. Achieving this objective would require extensive experiments in LP natural gas (or CH{sub 4}) flames for understanding the combustion phenomena underlying the formation of the exhaust pollutants. Although LP combustion is an effective way to control NO{sub x}, the downside is that it increases the CO emissions. The formation and destruction of the pollutants (NO{sub x} and CO) are strongly affected by the fluid mechanics, the finite-rate chemistry, and their (turbulence-chemistry) interactions. Hence, a thorough understanding of these interactions is vital for controlling and reducing the pollutant emissions. The present research is contributing to this goal by providing a detailed nonintrusive laser based data set with good spatial and temporal resolutions of the pollutants (NO and CO) along with the major species, temperature, and OH. The measurements reported in this work, along with the existing velocity data on a turbulent LP combustor burning CH{sub 4}, would provide insight into the turbulence-chemistry interactions and their effect on pollutant formation.


Sewage treatment plant with - in the direction of flow of the waste water - an anaerobic step and a denitrifying step, characterized in that it comprises a sedimentativ acting pre-treatment stage that the anaerobic stage are formed as an anaerobic fixed-bed reactor and the denitrification stage as denitrifying fixed-bed reactor and that it designed as a fixed-bed reactor aerobic post-purification stage comprises.


In this paper we report on new developments in the automatic meeting transcription task. Unlike other types of speech (such as those found in Broadcast News and Switchboard), meetings are unique in their richer dynamics of human-to-human interaction. An intuitive "fingernail" plot is proposed to visualize such turn-taking behavior. We will also show how recognition of short turns can be improved by building a language model tailored specifically for short turns. Out-Of-Vocabulary (OOV) words become a more salient problem in the meeting transcription task, as they are mostly topic words and proper names, lack of which not only causes Word Error Rate (WER) increase, but also limits further use of recognition hypotheses. We describe a prototype system which uses the Web as a source for vocabulary expansion, and present preliminary OOV retrieval results.


Objective: To find out the mental characteristic and evaluate the mental status and psychological problems of the peacekeeping officers and soldiers via MMPI survey.Methods: Carrying out group test with MMPI 399 questions version.Results: The results show that all the officers and soldiers mandated to the peacekeeping mission have preferable mental quality and well-balanced mental health.Discussion: The assessment could provide active psychological consultation and psychotherapy initiative aimed at the problem mirrored in the survey and acquire satisfying curative effect.


In portfolio analysis, there are a few models that can be used. Therefore, the aim of this paper is to make an overview on multi criteria decision making models, in particular, on ELECTRE methods. We discuss the different versions of ELECTRE, which exist and why they exist. So, when speaking about ELECTRE methods structure, we have to consider two main procedures: construction of one or several outranking relation(s) procedure, and exploitation procedure. In the exploitation procedure, recommendations are elaborated from the results obtained in the first phase. The nature of the recommendation depends on the problematic: choosing, ranking or sorting. Each method is characterized by its construction and exploitation procedure. For choice problem, we can apply ELECTRE I, ELECTRE Iv, and ELECTRE IS; for ranking problem, we can apply ELECTRE II, ELECTRE III, ELECTRE IV and ELECTRE-SS; and for sorting problem we can apply ELECTRE TRI. Finally, some failings on ELECTRE methods assumptions are discussed, for instance, rank reversals. So, when analyzing portfolio management decision problem, the literature suggests AHP method and PROMETHEE family.


The treatment of severe acute pancreatitis (SAP) is a difficult clinical problem. Hemofiltration has been used in the treatment of SAP for more than 20 years. Hemofiltration can clear excessively activated inflammatory factors of blood and block systemic inflammatory response syndrome (SIRS), while maintaining water-electrolyte balance. It plays an more and more important role in the treatment of SAP. At the same time, the application of hemofiltration in the treatment of SAP is also controversial and requires further study. This paper will summarize recent advances in hemofiltration for SAP so as to achieve better application of hemofiltration in clinical practice.

Key words:
Pancreatitis; Hemofiltration; Review


Drained residual shear strength is applicable to slopes containing preexisting shear surfaces and preexisting landslides. Laboratory ring shear testing by various researchers suggest the possibility of strength gain along preexisting shear surfaces which had previously obtained a residual strength condition. This paper presents back-analysis of two case histories that were used to suggest strength recovery to confirm test results developed herein and explain how the recovered strength may be useful in understanding slope behavior during the rest period and movement reactivation. These back-analyses are important to determine whether or not strength gain occurs and the practical significance, if any, of the strength gain in design of the remedial measures.


Objective To analyze the CT features of rare hepatic vascular-originated tumors,and to improve the realization to this kind of disease.Materials and Methods The clinical data and CT images of 4 cases with rare hepatic vascular-originated tumors confirmed by pathological were analyzed retrospectively,including location,size,shape,number,density,surrounding circumstances and distant metastasis.Results Of all the 4 cases,2 cases were liver angiosarcoma,and 2 cases were epithelioid hemangioendothelioma.Multiple lesions displayed in 3 cases(the diameter ranging from 0.9 ~ 15.0cm) and single lesion in 1 case(10.7 × 13.4cm).The tumor demonstrated as round or oval in 3 cases and irregular-shape in 1 case.There were ill-defined lesions in 2 cases and well-difined lesions in 2 cases.All cases showed low density.2 cases showed significant necrosis,and 1 case showed foliated bleeding lesions.In the arterial phase,2 cases showed enhancement in the central area of ?? the lesion.2 cases showed mild enhancement of the edge,and 1 case of them showed punctate shadow of vessels.During the venous phase,2 cases showed larger enhanced region than that of the arterial phase and the other 2 cases showed no significant changes.1 case showed pulmonary and splenic metastasis.Conclusion The clinical and imaging findings of rare hepatic vascular-originated tumors are not specific,so these diseases are often misdiagnosed as other diseases.It is nessisary to accumulate experiences and knowledge about this kind of diseases.


The article is dedicated to the problem of the innovative development of the Russian economy. It describes sequences of the 2008-2009 crisis for Russia and countries with developed economy and presents data of capital outflow. The trace metals production presents one of innovative direction of economy development. Trace metals present now one of the main components of innovation growth practically in all developed and developing countries. The study of different approaches to commercialize the financing of the projects is very important in trace metal production. The article presents different principal documents defining what financial resources are required when organizing innovative trace metals production. The trace metals distribution in the world and the domination position of PRC in the field is depicted. The data on research financing in Russia compared with other countries is demonstrated. Trace metals find a broad application in different branches and definitions "innovation economy" and "trace metals production" are closely linked. The trend of trace metals production in Russia and approximate financing volumes are presented.


When consumers experience problems with purchases the most frequent mechanism for their solution is complaint to the seller. This case study describes and attempts to evaluate the working of the complaint mechanism in handling the problems of purchasers of selected household appliances. The complaint mechanism was found to be commonly used and effective in handling matters defined by consumers as problematic, and consumers often seemed to obtain more generous concessions than the law required of the seller. The latter's response was liberal because management defined generous dealing with customers as consonant with long-run commercial interest, and because staff experienced both official and unofficial pressures to grant customers' requests.


By utilizing the extended linear expenditure system,this treatise used the data of Chinese urban and rural residents' per capita income and edible vegetable oil consumption to explain the situation and structure of urban and rural Residents'edible vegetable oil consumption.Also,this treatise calculated per capita amount of urban and rural residents' edible vegetable oil consumption according to each variety.Moreover,on basis of analysis of urban and rural residents' edible vegetable oil's three kind of demand elasticity,this treatise revealed the consumption character and trend of all kinds of oil,and compared urban and rural residents' consumption with each other.


This paper presents specific technical issues related to the development of virtual exhibitions for both web and mobile devices. Several real implementations of virtual exhibitions are described, based on the MOVIO platform (in the case of web applications) and on the Android operating system (in the case of mobile applications). A comparative analysis has been performed in order to reveal the advantages of each type of implementation, based on two virtual exhibitions implemented for the Romanian Academy Library.


Mobile ad hoc networks is a dynamic network,the dynamically joining and exiting of network node makes the network chat rooms facing a lot of security issues.The security is strengthened and the complexity is simplified by optimizing and designing a ticket-granting center in this paper.Through the establishment of Certificate Authority Center and ticket-granting,as well as implementation of access control scheme the optimization of the authentication and chat room access control is completed.The test shows that the new optimization solutions simplify the complexity and reinforce security of secured chat room in the members joining.


Stanislav Suchek on behalf of the ATLAS collaboration Kirchhoff-Institute for Physics, University of Heidelberg, email@example.com LHCP, Bologna, 5 June 2018 Signal models contribution comparable to or even stronger than the V H process, since its cross section is about 20 times larger and the jets originating from the initial state radiation are more central than in th VBF process. The free parameter of this model is the branching ratio BH inv.. The cross sections for the di erent Higgs boson production modes are taken to be given by the SM predictions. q


Building a universal quantum computer is a central goal of emerging quantum technologies and it is expected to revolutionize science and technology. Unfortunately, this future does not seem very close, however, quantum computers built for a special purpose, i.e., quantum simulators, are currently being developed in many leading laboratories. Numerous schemes for quantum simulation have been proposed and realized using, e.g., ultracold atoms in optical lattices, ultracold trapped ions, atoms in arrays of cavities, atoms/ions in arrays of traps, quantum dots or superconducting circuits. The progress in experimental implementations is more than spectacular. Particularly interesting are those systems that simulate quantum matter evolving in artificial, or synthetic, Abelian or even non-Abelian gauge fields. Abelian gauge fields are analogues to the standard magnetic field and lead to fascinating effects such as the integer or fractional quantum Hall effects (IQHE, FQHE) and vortex lattices. Non-Abelian gauge fields couple the motional states of the particles to their internal degrees of freedom (such as hyperfine states for atoms or ions, electronic spins for electrons, etc). In this sense, external non-Abelian fields extend the concept of spin–orbit coupling, which is familiar from AMO and condensed matter physics. They lead to yet another variety of fascinating novel phenomena such as the quantum spin Hall effect (QSHE), 3D topological insulators, topological superconductors and superfluids of various kinds. Even more fascinating is the possibility of generating synthetic gauge fields that are dynamical, i.e., that evolve in time according to the corresponding lattice gauge theory (LGT). These dynamical gauge fields can also couple to matter fields, allowing the quantum simulation of such complex systems (notoriously hard to simulate using 'traditional' computers), which are particularly relevant for modern high-energy physics. So far there are only theoretical proposals for simulating Abelian LGTs, but many groups are working on extensions to the non-Abelian scenarios. The scope of this special issue of Journal of Physics B: Atomic, Molecular and Optical Physics is on all of these developments, with particular emphasis on the non-Abelian case. We invite the leading theory and experimental groups to contribute to this very special issue of the journal in order to provide a reference collection for quantum simulations of gauge fields. To summarize the key features should be Synthetic spin–orbit coupling and the physics of topological insulating phases Strongly correlated phases in non-Abelian gauge potentials Dynamical non-Abelian gauge fields and the simulation of lattice gauge theories Spin–orbit coupled BEC and vortex physics Simulators of Abelian LGTs Simulators of non-Abelian LGTs You are invited to submit your article by 15 December 2012. Expected publication: Summer 2013. Synthetic spin–orbit coupling and the physics of topological insulating phases Strongly correlated phases in non-Abelian gauge potentials Dynamical non-Abelian gauge fields and the simulation of lattice gauge theories Spin–orbit coupled BEC and vortex physics Simulators of Abelian LGTs Simulators of non-Abelian LGTs Corrections were made to this article on 7 November 2012. A change was made to the affiliations.


On the industrial side, the selection of materials for a product produced by a company must be following the function and purpose of the product. There are many types of materials used by various companies in the manufacture of a product, one of which is aluminium. This study aims to determine the effect of temperature variations of 3% Al-TiC Composite Heat Treatment 350°C, 450°C, 550°C on the mechanical properties and microstructure with the cooling slope method. The casting process is carried out using A356 aluminium material and the addition of 3% titanium carbide (TiC). The casting results are poured into a permanent mould through a cooling slope with a pouring angle of 45°. And finally carried out by heat treatment on the test object with temperature variations of 350°C, 450°C, 550°C with oil cooling media SAE 40. The highest hardness was obtained at a heat treatment temperature of 550°C with a value of 64.25 BHN, at a temperature of 450°C with a value of 60.02 BHN, and 350°C with a value of 56.59 BHN. The highest tensile strength was obtained at a heat treatment temperature of 550°C of 219,862 MPa, a temperature of 450°C of 183,273 MPa, and 350°C of 164,328 MPa. The obtained microstructure shows hypo-eutectic silicon dispersed among the aluminium. The microstructure shows that the homogenization of silicon and TiC at a heat treatment temperature of 550°C is very good, as evidenced by the uniformly dispersed density of the alloy filling the aluminium matrix.


The term digital divide (digital social inequality, also a "first world problem") refers to the gap between demographics and regions that have access to modern information and communications technology and those that don't have access. The primary aim of the paper is to look at the very concept of the digital divide, as well as the possibility of bridging it in order to achieve the fundamental goal embodied in a more inclusive Europe, using the latest EUROSTAT data, for the years 2019 and COVID-19 2021. The paper performs a classical comparison of quantitative information of observed phenomena according to various criteria and from different time frames, specifically before the pandemic and during the pandemic. A more detailed review of the literature points to the persistence of the gap of both the first (material access), and the second (skills and uses) and the third level (outcomes of differentiated access and use) in the European Union, which is also evident in the conditions of the COVID-19 pandemic which has confirmed the need to turn to digital transformation which is accelerated and adequately managed. The digital divide is manifested between the EU Member States, with a particularly pronounced dividing line between northern and southern European countries. In order to narrow digital divide as much as possible, a strong commitment is needed, not only from policy makers at EU level, but also from Member States, primarily towards raising investment in research and innovation, the diffusion of ICT literacy and the deployment of smart technologies for society.


Based on the same theory, we once wrote the two papers on the geometry of points dividing a fixed rectifiable closed curve in 3-dimensional euclidean space into special number of parts of equal length. The one* deals with the analytical geometry in the space and the other** with differential geometry. This paper deals with some problems of differential geometry and position vectors. In the following, the space denotes 3-dimensional euclidean space. Let us take a rectifiable closed curve C having the constant lengh 1 and the definite direcstion, and we assume it is of class C3. If we take the original point 0 on it since any point P on it can be expressed by the arc length s measured from 0 to P, every point P on C can be denoted by the symbol P (s), where o s 1. We shall consider the system of the points Pi, i=1,2 ordered along the curve C, dividing it into two parts of equal length. Let Si be the arc length of OP.z. We shall take a fixed rectangular coordinate system 0-xi x2 x3, and if we denote the coordinates of the points P on a fixed closed curve C by (xi 4), all these coordinates are continuous functions of s1. Therefore, the system = (P i (s i), i=1, 2} is a function of si. The osculating planes at the points P (5 i) on the curve C are represented by (1) I x—xi (se) xi' (se) x (s t) o, (i=/, 2) where


This study aimed to detect short-duration Atrial Fibrillation (AF) episodes by studying inter-beat interval time series to reach real-time automatic medical monitoring. Four publicly-accessible sets of clinical data were used for assessment. All time series were segmented in 1-min RR interval windows and then three specific features were calculated, namely, Vector Angular Index, Vector Length Index and Dispersion of points along the perpendicular to the diagonal line. The features of the four databases were merged in order to give rise to huge variability and therefore to better characterize AF rhythm. Principal Component Analysis (PCA) was used to elucidate whether it was possible to discriminate between AF and Normal Sinus Rhythm (NSR) and Learning Vector Quantization (LVQ) neural network has been optimized to develop the classification model. PCA analysis has shown a good discrimination between the studied rhythms. Furthermore, despite its very simple structure, LVQ neural network has performed better on the analysed databases than existing algorithms did, with high sensitivity and specificity respectively of 99.19% and 99.39%.


The introduction of foreign potato resources can expand parent materials and enrich China's potato resources.This article deals with the current introduction of virus-free potato seeds from abroad and presents the techniques to propagate the introduced seeds in terms of establishing tissue culture lab,culture conditions,selection of culture medium,management of insect-free room,and inspections.


This report discusses carbon steel castings which are used for a number of different components in nuclear power plants, including valve bodies and bonnets. Components are often repaired by welding processes, and both welded components and the repair welds are subjected to a variety of postweld heat treatments (PWHT) with temperatures as high as 899{degrees}C (1650{degrees}F), well above the normal 593 to 677{degrees}C (1100 to 1250{degrees}F) temperature range. The temperatures noted are above the A1 transformation temperature for the materials used for these components. A test program was conducted to investigate the potential effects of such ``nonstandard`` PWHTs on mechanical properties of carbon steel casting welds. Four weldments were fabricated, two each with the shielded-metal-arc (SMA) and flux-cored-arc (FCA) processes,with a high-carbon and low-carbon filler metal in each case. All four welds were sectioned and given simulated PWHTs at temperatures from 621 to 899{degrees}C (1150 to 1650{degrees}F) in increments of 56{degrees}C (100{degrees}F) and for times of 5, 10, 20, and 40 h at each temperature. Hardness, tensile, and Charpy V-notch (CVN) impact tests were conducted for the as-welded and heat-treated conditions.


This paper develops necessary and sufficient conditions on an algebraic semigroup S in order that it will have nontrivial right group homomorphic images. A central notion used is that of how the normal subsemigroups associated with the group images of S relate to the right group images of S. The results presented thus extend those of R. R. Stoll. Where right group congruences exist, the structure of S is determined and the right group congruences are characterized in terms of group congruences and right zero congruences on S. Sufficient conditions are then found for the existence of a minimum right group congruence on S, and isomorphic right group congruences and the minimum right group congruence on S are described. Lastly, an application is made to regular semigroups whose idempotents form a rectangular band.


In this paper we introduce and apply three concepts that are new to the field of Industrial Networks, using the Critical Realist ontology due to Margaret Archer. Constitutiveness is the property of an entity that makes it essential to the existence of another entity. For example communication is constitutive of organizations since they cannot exist without communication. Co-constitutiveness exists when two entities mutually constitutive one another. An example would be a manager and a subordinate in an organization. Micro-macro emergence describes the processes by which macro outcomes, such as the launch of a new product line, emerge from micro activities such as person to person conversations. These three concepts are exemplified through the use of a case study based on data collected in an organizational action research project. We conclude that this set of concepts offers a new and valuable way to understand the complexities of organizational and interorganizational worlds.


An improved herbicide composition is one kind of mixture comprising 2-(4,6-dimethoxy pyrimidyl-2-aminoformamidosulfonyl)-N,N-dimethyl nicotinamide and at least one of 1,4-D butylate, metribuzin, sulcotrione and atrazine. It has high herbicidal effect to crab grass, green bristle grass, goose grass, etc. in corn field, and its herbicidal effect is higher than that of its single component.


Driver assistance systems based on camera are strongly disturbed by the presence of foggy weather. The restoration of images, as pre-processing, would improve the performances of such systems. In this paper, we propose a method to restore the image contrast of foggy road scenes combining a physical approach, based on Koschmieders model and a signals approach, based on local histogram equalization. Then we optimize the parameters of our method using a simulated annealing. This method, evaluated on a reference image database, presents a significant improvement compared to other methods and gives consistent results for both homogeneous and inhomogeneous fog.


Abstract Celestial positioning has been used for navigation purposes for many years. Stars as the extra-terrestrial benchmarks provide unique opportunity in absolute point positioning. However, astronomical field data acquisition and data processing of the collected data is very time-consuming. The advent of the Global Positioning System (GPS) nearly made the celestial positioning system obsolete. The new satellite-based positioning system has been very popular since it is very efficient and convenient for many daily life applications. Nevertheless, the celestial positioning method is never replaced by satellite-based positioning in absolute point positioning sense. The invention of electro-optical devices at the beginning of the 21st century was really a rebirth in geodetic astronomy. Today, the digital cameras with relatively high geometric and radiometric accuracy has opened a new insight in satellite attitude determination and the study of the Earth's surface geometry and physics of its interior, i.e., computation of astronomical coordinates and the vertical deflection components. This method or the so-called astrogeodetic vision-based method help us to determine astronomical coordinates with an accuracy better than 0.1 arc second. The theoretical background, an innovative transformation approach and the preliminary numerical results are addressed in this paper.


The purpose of this paper is to analyze personnel rotation in the Navy. Although primarily a sea-going force, the Navy must periodically rotate personnel to shore duty. The effective administration of this policy promotes morale and reduces attrition. It also enables managers to control the distribution of personnel, so that programmed changes in force manning levels can be implemented gradually without disrupting individual career development. In order to accomplish this, however, Navy planners must understand the effect alterations in individual parameters will have on the system. A simplified mathematical model is developed and analyzed to help clarify these interrelationships. The results of this analysis are applied to answer some important questions concerning the present enlisted force.


Objective:To investigate the behavior risk factors for cervical cancer in younger patients.Methods:48 consecutive patients with cervical cancer admitted to hospitals in Zhanggong division,Ganzhou,Jiangxi during September 2008 to January 2010 and a randomly selected control group(n = 75) were comprehensively investigated with a self-designed questionnaire.All the data obtained were transferred to a data bank and analyzed statistically in SPSS.Results:Significant statistical differences between the cervical cancer group and the control group were found in some indexes including passive smoking,abortion times,sexual life frequency.Conclusion:Recognition of the behavior risk factors related to the incidence of cervical cancer and the incidence in young women can provide new ideas for the prevention of cervical cancer and help guide the women's lifestyle changes to avoid behavior risk factors and prevent cervical cancer etiologically.


The climate effect and environmental pollution caused by dust discharged into the atmosphere have attracted much attention. However, the driving factors of dust emissions have not been studied thoroughly. Here, spatiotemporal variations in dust emissions and the relationship between dust emissions and large-scale atmospheric circulation in East Asia from 2000 to 2021 were investigated using Modern-Era Retrospective Analysis for Research and Applications version 2, Cloud-Aerosol Lidar Pathfinder Satellite Observations, ERA5 reanalysis data, and climate indices. Results showed that the Taklimakan Desert in the Tarim Basin, the Gurbantonggut Desert in the Junggar Basin, the Turpan Basin, and the Gobi Desert in western Inner Mongolia and southern Mongolia are the main sources of dust emissions in East Asia. The period of strong dust emissions is from March to May, and emissions to the atmosphere were mainly distributed at 0–4 km in the troposphere. In the eastern and southwestern Tarim Basin, northern Junggar Basin, and parts of the Gobi Desert in southern Mongolia, dust emissions have significantly increased over the past 22 years, whereas in the southwestern Tibetan Plateau, southwestern Inner Mongolia, and a small part of the northern Mongolian Gobi Desert there was a significant decreasing trend. The winter North Atlantic Oscillation (NAO) and Arctic Oscillation (AO) were significantly negatively correlated with East Asian dust emissions the following spring. The various phases of the AO/NAO coupling have clear different effects on East Asian dust emissions in the spring. When the AO/NAO coupling was negative (positive), the East Asian trough and Siberian High were strengthened (weakened), the frequency of cold air activity increased (weakened), 800 hPa wind speed strengthened (weakened), and East Asian emissions increased (decreased). In AO−/NAO+ years, the Asian polar vortex was stronger to the south and the East Asian trough was stronger to the west. The Lake Baikal trough was in the deepening phase, which caused more polar cold air to move into East Asia, aggravating the intensity of dust activity. In the AO+/NAO− years, the Siberian High and East Asian trough weakened, which was unfavorable to the southward movement of cold air from Siberia. Therefore, the frequency of windy weather in East Asia decreased, partly weakening dust emissions. However, a positive geopotential anomaly in northeast China and a negative geopotential anomaly in South Asia triggered an anomalous enhancement in easterly wind in the tropospheric area over northwest China. Strengthening of the Balkhash trough provides favorable conditions for gale weather in northwest China. The frequency of gale weather increased, and dust emissions were enhanced in northwest China.


Conclusion. The singular neurectomy as described by Gacek in 1974 is an efficient procedure to control symptoms in case of intractable benign paroxysmal positional vertigo (BPPV), with an acceptable risk of postoperative sensorineural hearing loss (SNHL). We postulate that this complication may not be a direct consequence of the surgical procedure but rather may be consecutive to the reactivation of the biological phenomenon that caused the BPPV. We also observed in one patient that BPPV may exist although no nystagmus can be elicited by provocative manoeuvres. Objective. To report our experience of the surgery, and to analyse the rate and causes of complications. Patients and methods. The eight patients operated in the department between August 1997 and April 2006 were evaluated in June 2006. One had been operated because he had a typical history of BPPV, but no nystagmus could be elicited by the Hallpike's manoeuvre. Results. All patients were free of vertigo and considered their quality of life improved. The Hallpike's manoeuvre was negative in all cases. A SNHL occurred in two patients, immediately after surgery in one and several months later in the second. The patient with a negative Hallpike's manoeuvre before surgery went back to work 3 weeks after surgery.


The new ecology of monitoring network and artificial intelligence (AI) has injected new vitality into traditional education and brought new opportunities for the development of education. We implemented the online big data (BD) physical education classroom based on monitoring network and AI, as well as the integrated teaching practice of health data inside and outside the physical education classroom, built a practice model integrating data collection, data analysis, and data application, and explored its practical effectiveness using the literature method and mathematical analysis method. The results show that the practice can achieve data management of physical education courses, promote the improvement of students' physical health, achieve the purpose of real-time monitoring of students' independent exercise status, and achieve the goal of getting students out of the dormitory and into the playground.


The higher education environment is undergoing significant change as it enters a global knowledge-based economy. Technology now enables students to undertake studies that are time and place independent. To thrive in a networked learner environment, new strategic relationships must be created between library and information professionals, information and education technologists, trainers and staff developers, instructional designers and media designers and producers. The University of Newcastle sought strategic advantage through integrating its information, education and technology services in early 1997. This paper explores the rationale for the formation of the division and the strengths and weaknesses of this approach as highlighted through a recent external review. Contains 11 endnotes.


Basically, the property right shall be firmly awarded to the person who conducts the invention, provided that such invention should fulfill all the conditions and requirements stipulated by the patents act, as the invention is the product of his/her intellectual effort and materialistic work. This right is a genuine property right, duly determined by the different laws. But one may hold a contract with another person to conduct this invention; and the right of this contracting person (the employer) will be focused on the proprietorship of these inventions. So the purpose of conducting the contract is that the worker (employee) will carry out the search, experiments that lead to the invention. Once the employee completes the invention, then the employer will be confirmed with all the financial rights entailed by this contract. Therefore, what is the legal nature of the employer's property right in the ownership of the invention made by the worker during the validity period of the contract?


Background: There are few therapeutic options for higher risk patients with myelodysplastic syndrome (MDS) who fail standard therapy, and their 2-year survival rate is approximately 15%. Here we report on a recently initiated collaborative (industry-academia) first-in-human phase 1 clinical trial to assess the safety and tolerability of a novel form of adoptive T cell immunotherapy for such patients that targets patient and disease-specific, mutation-derived neoantigens. This experimental therapy is based on the concept that a) cancer is caused by somatic mutations that may generate novel immunogenic proteins (ie, neopeptides and possible neoantigens), b) that the adaptive immune system can be trained ex vivo to recognize neopeptides as neoantigens and c) that infusion of culture-expanded, neoantigen-immunized autologous T cells may be safe and therapeutically effective.
 Methods: This is an open-label, phase 1, 3+3 dose escalation trial with 3 cell doses (0.3, 1, and 3.0 × 107nucleated cells/kg) in cohorts of 3 patients each (see www.clinicaltrials.gov, NCT-03258359). Eligible subjects are 18 years of age or older and will have Intermediate, High, or Very High risk MDS by the revised International Prognostic Scoring System, with at least one cytopenia, and will have failed or relapsed after 6 cycles of standard hypomethylating therapy or declined such therapy, an ECOG status 0-2, and adequate organ function. Each patient's MDS-related mutations are identified and autologous T cells are immunized ex vivo with peptides corresponding to the mutated protein(s), then expanded and suitability-tested for experimental infusion (referred to as PACTN). Importantly, the T cells must demonstrate neoantigen specificity and must kill autologous MDS stem-progenitor cells prior to qualification for infusion. Each eligible subject receives a single infusion of autologous PACTN followed by intensive monitoring for adverse events (AEs) for 4 weeks and periodic monitoring for 1 year. The primary study end-point (EP) is assessment of dose-limiting toxicity (DLT) and maximum tolerated PACTN dose (MTD). Secondary EPs include disease response 1 month after PACTN infusion, overall and progression-free survival at 6 and 12 months, and assessment of the peak abundance and persistence of the infused T cells in peripheral blood. Exploratory EPs include an assessment of the effect of PACTN infusion on the allele frequencies of the targeted and non-targeted MDS mutations in blood and marrow leukocytes.
 Results: At this time, two subjects have been infused with PACTN in the first dose cohort. Neither subject had an infusion reaction, severe AE, or DLT after follow-up for 2-3 months, nor has a disease response occurred in these subjects. Of interest, the infused PACTN product in the first subject showed 59% clonal dominance by a single T cell receptor (TCR) clone that was present at only 0.002% in patient's blood prior to T cell immunization with neoantigen related peptides. Multiple additional expanded TCR clones were also identified in the infused PACTN product. The presence of a dominant TCR clone in the PACTN product enabled the assessment of the in vivo abundance and persistence of the clone after PACTN infusion. The dominant clone expanded between day 1 and day+4 after PACTN infusion to a peak frequency of 0.13%, representing a 64-fold expansion of this TCR compared with the pre-infusion sample of blood leukocytes, then decreased to 0.09% by day +8. The clone was also demonstrated in bone marrow on day +15 at a frequency of 0.03%, representing a 20-fold expansion of this TCR clone compared with the pre-infusion marrow sample. Similar studies on the second subject are in progress, and will be continued in future subjects as the clinical trial continues. Finally, our studies show that it has been possible to effectively immunize autologous T cells to patient-specific neoantigens in all patients studied with MDS (n=4) and also all patients with AML (n=3) studied to date.
 Conclusion: The early results of this clinical trial support the feasibility and safety of this novel approach to adoptive T cell mediated immunotherapy for patients with higher-risk MDS and encourages continuation of the trial in the higher dose level cohorts.

 Ferrari: Persimmune, Inc.: Employment. Tarke:Persimmune, Inc.: Employment. Fields:Persimmune, Inc.: Employment. Ferrari:Persimmune, Inc.: Employment. Ni:Persimmune, Inc.: Employment. Ferrari:Persimmune, Inc.: Employment. Warner:Persimmune, Inc.: Employment. Jochelson:PersImmune, Inc.: Consultancy. Bejar:Celgene: Consultancy, Honoraria; AbbVie/Genentech: Consultancy, Honoraria; Takeda: Research Funding; Genoptix: Consultancy; Modus Outcomes: Consultancy; Foundation Medicine: Consultancy; Astex/Otsuka: Consultancy, Honoraria. Vitiello:Persimmune, Inc.: Employment. Lane:PersImmune, Inc.: Employment.


Background:  Seed storage proteins (SSP; Ara h 1, Ara h 2, Ara h 3) have been shown to be major peanut allergens, although recently, peanut lipid transfer protein has been reported to be an important allergen in the Mediterranean area. We sought to investigate the sensitization pattern to peanut SSP and vegetable pan‐allergens in a group of peanut‐allergic children compared with a peanut‐tolerant group.


We analyze a semiparametric model for data that suffer from the problems of incidental truncation, where some of the data are observed for only part of the sample with a probability that depends on a selection equation, and of endogeneity, where a covariate is correlated with the disturbance term. The introduction of nonparametric functions in the model permits significant flexibility in the way covariates affect response variables. We present a Bayesian method for the analysis of such models that allows us to consider general systems of outcome variables and endogenous regressors that are continuous, binary, censored, or ordered.


The chylomicron remnant particle is thought to be particularly atherogenic and we have previously shown alterations in post-prandial lipoproteins which could contribute to their atherogenicity. Cholesterol metabolism is disturbed in diabetes, yet the effect of diabetes on intestinal cholesterol synthesis and absorption has rarely been investigated. The aim of this study was to examine cholesterol absorption and intestinal synthesis of cholesterol in the streptozotocin diabetic rat. Twelve diabetic rats were paired with 12 control rats. [14C]-Cholesterol emulsion was administered and the lymph duct was canulated. Lymph was collected for 4 h. At sacrifice blood was taken for plasma lipoprotein measurements. Chylomicrons were prepared from the lymph by ultracentrifugation and [14C]-cholesterol content was determined by liquid scintillation counting. Lymph apolipoprotein B48 was isolated by gradient gel electrophoresis, and quantified by densitometric scanning. Serum triglyceride and cholesterol were greatly elevated in diabetic compared to control animals (260 ± 90 and 9.8 ± 8.0 mg/ml vs. 1.0 ± 0.4 and 0.6 ± 0.3 mg/ml, p < 0.0001 respectively). Lymph chylomicron apo B48 was similar in the two groups. Cholesterol absorption was not significantly different in diabetic compared to control rats but cholesterol synthesis was significantly, higher in the diabetic animals (550 ± 352 vs. 322 ± 113 μg/h p < 0.03). There was a positive correlation between apo B48 and cholesterol absorption (r = 0.70, p < 0.01) in the diabetic rats and control rats (r = 0.71, p < 0.01) but no correlation between apo B48 and cholesterol synthesis in either group. This study demonstrates that cholesterol synthesis was increased in diabetes whereas cholesterol absorption was unaffected suggesting that intestinal cholesterol synthesis made an important contribution to the hypercholesterolaemia seen in the diabetic animals.


Dyah Wahidatun Hasanah, Islamic Learning Methods for the Blind Man in the Women's Social Care Institution Wanodytama Surakarta Social Service Disability House Netra Bhakti Candrasa Surakarta. Essay. Surakarta: Department of Islamic Religious Education Faculty of Islamic Studies Muhammadiyah University of Surakarta, 2017, The background is to know the implementation of Islamic learning for the blind at Rumah Sosial Sosial Disabilitas Netra Bhakti Candrasa Surakarta. The problem in this research is how the method used in the learning process of Islam in the House of Social Services Disabilitas Netra. This study aims to describe the methods used in the learning process of Islam in the House Social Services Disabilitas Netra Bhakti Candrasa Surakarta, This research is a qualitative research, by taking place background in Social Disability Service House Netra Bhakti Candrasa Surakarta. Data collection is done by observation, interview and documentation. Data analysis is done by arranging the data obtained by systematic, then analyzed and given the meaning and from that meaning is conclusion.
The results showed that the methods used in the learning process of Islam at Rumah Disabilitas Social Services Netra Bhakti Candrasa Surakarta include: Lecture Method, Discussion, Question Answer, Drizz or Exercise. In addition to the methods of class discovery was also found a method used in guidance outside the classroom that is Method of Coaching and Counseling.


Stevia (Stevia rebaudiana Bert.) is a relevant source of natural phenolic compounds with antioxidant and antimicrobial properties. The aim of this study was to evaluate the potential protective effect of crude stevia extracts on the quality and shelf-life of salmon (Salmo salar) paste. For this, polyphenol extracts obtained by water extraction, ethanol/water extraction and supercritical CO2 with ethanol extraction were evaluated in preserving salmon paste. Salmon paste was stored under refrigerated conditions (5 °C) for 21 days, being primary, secondary and total lipid oxidations monitored along storage by means of peroxide, p-anisidine and TOTOX indices, respectively. In addition, ω3/ω6 ratio, polyene index and α-tocopherol were monitored. Microbiological analysis comprised the investigation of aerobic mesophiles and psychrotrophes. Salmon paste samples treated with ethanol/water and supercritical CO2-Ethanol stevia extracts exhibited the highest (p<0.05) ω3/ω6 ratio and α-tocopherol content. Besides, partial inhibition of both primary and secondary lipid oxidation events and aerobes and psychrotroph growth was also observed in both samples. These results correlated with the fact that Ethanol/water and supercritical CO2-Ethanol extracts provided the highest DPPH and FRAP values. These results open the way to the utilisation of bioactive compounds from stevia leaves for the preservation of foods derived from salmon.

Practical applications: The results obtained in this research show the possibility of using stevia and / or its derivatives of the sweetener industry as an alternative source of natural antioxidants in refrigerated fatty fish paste. The results indicate that it is possible to obtain advantages in the refrigerated salmon paste, based on the use of some extracts of stevia, which can help to inhibit lipid oxidation and development of pathogenic microorganisms. Further studies on the use of stevia and its derivatives should focus on the application of clean separation technologies such as supercritical fluid extraction.


DESCRIPTION: Many marketing models include the notion of distance between points as a variable characterizing a process. For example, gravitational models attempting to explain sales at retail sites as a function of distance from population centers posit an inverse relationship between sales and distance of consumers from the point of distribution [l, pp. 312-23]. In the empirical stage of model verification, available data may include the address of the buyer. To determine the distance of buyers from the point of sale (the factory, warehouse, or retail outlet), one may have to resort to measuring distances between points on available maps. As the number of observations increases, the time requirement of this manual process may well become prohibitive. Hence, the need for a computer routine to facilitate this distance calculation. DISTAN is a FORTRAN subroutine that fills part of this need. For a given input of two five-digit zip codes, this subroutine determines the distance between the points represented by their zip codes. Formulae from analytical geometry are used to determine the angle between the locations, from which the distance between them can be readily obtained. The output from this subroutine is the distance between the two zip code locations. Invalid input zip codes generate appropriate error messages.


Introduction: The occurrence of right heart thrombus (RiHT) in pulmonary embolism (PE) carries poor prognosis. Type A Thrombi are serpiginous, highly mobile with high mortality. Type B Thrombi are less mobile and have better prognosis. Type C is intermediate in all characteristics. Methods: This is an observational study done in patients presenting with RiHT with PE to the emergency unit of our institute from March to August 2016. A total of seven patient's clinical and electrocardiographic data were collected with a history of deep vein thrombosis or hypercoagulability. Results: This case series of seven patients with right heart thrombi in pulmonary embolism showed a predominance of male patients, with right ventricle dysfunction and pulmonary hypertension in all cases. Conclusion: Early fibrinolysis in type A thrombus had a favourable outcome. Mortality was 29% in our series.


A growing number of reports suggest that elevated levels of extracellular Alzheimer's β-amyloid protein alter the homeostasis of free [Ca2+] i in different cell types of the mammalian brain. In line with these results, we have previously shown that AβP[1–40] forms cation-selective channels (Ca2+ included) across artificial planar bilayers formed from acidic phospholipids and across excised membrane patches from immortalized hypothalamic GnRH neurons (GT1-7 cells), suggesting that the nonregulated Ca2+-influx through these spontaneously formed "amyloid channels" may provide a mechanism to explain its toxicity (1). We have now found and report here that the application of AβP[1–40] to GT1-7 neurons consistently elevates [Ca2+] i levels. We also found that human islet amylin and the prion protein fragment (PrP106–126), peptides that acquire β-pleated sheet conformation in water solutions and have been reported to form ion channels across planar bilayer membranes, also increase cytosolic free calcium in GT1-7 neurons. Searching for protective agents, we found that soluble cholesterol, known to decrease the fluidity of the cell membrane, inhibits AβP[1–40]-evoked [Ca2+] i rise. These results suggest that unregulated Ca2+ entry across amyloid channels may be a common mechanism causing cell death, not only in diseases of the third age, including Alzheimer's disease and type 2 diabetes mellitus, but also in prion-induced diseases.


Two studies were conducted, one involving adoption of an exercise program and the other involving adherence to an aerobics exercise program. Consistent with action control theory, it was hypothesized that (a) subjective expected utility theory would predict exercise intentions but not exercise behavior in each study; (b) exercise adoption (Study 1) and attendance at an aerobics class (Study 2) would be predictable from the intentions regarding these behaviors expressed by action-oriented but not state-oriented subjects; and (c) subjects who had engaged in planning in regard to exercising would be more likely to adopt an exercise program (Study 1) and would exercise more frequently (Study 2). The findings provide some support for all three hypotheses. Implications of this research are discussed in regard to the distinction between decision making and decision implementation or action control; the relative usefulness of an action-control versus an expectancy-value approach for behavior involving complex decision implementation over a long period of time; the value of action orientation as a moderator of intention-behavior relationships; and the role of planning in exercise behavior.


Loop Quantum Cosmology yields two kinds of quantum corrections to the effective equations of motion for cosmological perturbations. Here we focus on the holonomy kind and we study the problem of the closure of the resulting algebra of constraints. Up to now, tensor, vector and scalar perturbations were studied independently, leading to different algebras of constraints. The structures of the related algebras were imposed by the requirement of anomaly freedom. In this article we show that the algebra can be modified by a very simple quantum correction, holding for all types of perturbations. This demonstrates the consistency of the theory and shows that lessons from the study of scalar perturbations should be taken into account when studying tensor modes. The Mukhanov-Sasaki equations of motion are similarly modified by a simple term.


Crystallization at low temperature, in particular wherein the specific oxide of lithium disilicate glass ceramic and glass containing monovalent elements suitable for dental materials. Lithium disilicate glass ceramic of the present invention is characterized in that it comprises an Rb 2 Glass-ceramic, a monovalent metal oxide or mixtures thereof from 0.1 to 17.0% by weight, in particular, 1.0 to 15.0% by weight, particularly preferably of 1.5 to 8.0 wt% it is preferred to include an amount.


The tightness of electro-technical components for dust entrapment is an extremely important parameter to be considered for effective functioning. International Electro-technical Commission (IEC) developed standards for testing the parts under severe environments like rain, dust etc. The procedure for developing and conducting the dust proof test is known by IEC as 60068-2-68 standard. The blower is an essential component used in the dust test system in order to create a forced airflow along with dust to simulate a dusty environment. The radial tip centrifugal blower is designed in this work for the application of dust test chamber. The pressure and velocity of airflow at the outlet of the radial tip centrifugal blower is mostly influenced by inlet blade angle (β1), impeller diameter (D2) and impeller width (b). The design procedure is elaborated and the above said design parameters are optimized using iterative procedure using MATLAB software. A numerical analysis is carried out using ANSYS Fluent software for the design of Taguchi L9 orthogonal array. In the perspective of further exploring the relationship between design parameters of blower and output parameters like pressure and velocity, a statistical analysis is carried out using Design-Expert software. The optimized design parameters are then used for manufacturing the blower. The experimental test is carried out on the designed blower. The experimental, numerical and statistical results for the optimized design parameters are compared and known to be in good consensus.


The bronze image of the Buddha enshrined in the Mahamuni pagoda in the city of Mandalay, Myanmar, has a long history stretching back to more than twenty centuries. This ancient statue, known as the Mahamuni image, is most sacred to Burmese Buddhists due to its religious and historical significance. Hence, pilgrims and devotees, Buddhists or not, travelers and tourists from around the world visit the great Mahamuni image all the year round.


The code MBIM1 for the calculation of the coherent oscillations stability for multibunch beams in storage rings is presented. The multibunch beams with arbitrary charges of bunches are considered, including counterrotating beams (in approach of short bunches in comparison with minimal wavelength of considered environment RF spectrum), with the account of beams coupling with the environment (i. e. RF cavities or/and smooth vacuum chamber with walls of finite conductivity). The code uses the approach of small shifts of coherent frequencies, when different multipole types of synchrotron oscillations can be treated as independent from each other.