The Intelligent Meteorological System (IMS) with cloud computing (CC) provides users with various meteorological services, but the long-distance communication of CC often brings high latency, which makes the IMS perform poorly in the series of real-time services for meteorological emergency decision-making. Considering the shortcomings of CC, edge computing is adopted to the IMS to process most service requests. In the IMS with cloud-edge computing, the commonly used contents of services is cached on edge servers (ESs) to reduce resource scheduling, thus avoiding high time costs. Due to the storage and computing resource limitations of ESs, the massive types of services and the changing service requests, how to determine the caching contents is still a challenge. In this paper, a service caching scheme based on deep reinforcement learning, named SCDR, is proposed. Specifically, a service caching framework for IMS with cloud-edge computing is designed. Then, the distributed distributional deep deterministic policy gradient (D4PG) is leveraged to realize the optimization of the service caching strategy with the highest service coverage rate and low processing latency. Besides, the performance of the generated caching strategy is evaluated through simulation experiments.


The theory of Newton-Okounkov bodies, also called Okounkov bodies, is a relatively new connection between algebraic geometry and convex geometry. It generalizes the well-known and extremely rich correspondence between geometry of toric varieties and combinatorics of convex integral poly- topes. Following a successful MFO Mini-workshop on this topic in August 2011, the MFO Half-Workshop 1422b, "Okounkov bodies and applications", held in May 2014, explored the development of this area in recent years, with particular attention to applications and relationships to other areas such as number theory and tropical geometry.


A new monitoring system has been designed, permitting to control the beams of charged and neutral projectiles. The monitoring system uses the detection of electron emission. This construction allows control the flux of the particles without interruption of the beam. The monitoring is independent of direct ion current being detected in course of the actual measurement. Therefore it lends itself ideally to the spectrum normalization for the insulating samples and in cases of low beam currents. This arrangement allows to control the projectile fluxes from 10 to 10 particles/s⋅sm.


This retrospective report presents findings on 7 patients with idiopathic dilated cardiomyopathy who underwent transplantation of autologous bone marrow derived mononuclear cells (BMSC) after failed routine conservative treatment, and were on a waiting list for cardiac transplantation. In two out of seven patients, we performed intramyocardial delivery of BMSC twice, 22 and 24 months respectively after the first transplant. All patients received anti-congestive therapy by diu-retics, ACE inhibitors, carvedilol, digitalis and aspirin. We discuss potential disadvantages of intracoronary injections of autologous bone marrow stem cells. We believe that our BMSC transplantation method as opposed to intravascular input is the method of choice, particularly in children with idiopathic dilated cardiomyopathy because it is safe, gentle and is not associated with risks for coronary circulation.


The endocrine system as an indicator of stress and a means of evaluating animal welfare has been examined in this review. Stress endocrinology is an evolving area of study with many research questions to challenge scientists. However, for the past 25 years, the welfare of domestic animals has been an important aspect of animal science. Consequently, scientists have searched for objective ways to evaluate welfare, in that the demonstration of stress indicators could provide an objective information about how well farm animals kept under production conditions have adapted to the environment. Potential indicators have been suggested, both behavioural and physiological stress indicators among others. The endocrine system may be used as indicators of stress. The primary role of hormone may be a part of the homeostatic response to a stimulus (e.g. adrenaline, corticosteroids). The amplitude of hormone response may correlate with the severity of the stimulus. Moreover, a hormone may have a key role in normal body function (e.g. reproduction) and stress may deleteriously alter the hormone, signal prevents normal function. While stress inputs may reduce over time, hormone negative feedback is a major factor reducing hormone responses. This explains a reduction in perceived stimulus severity or habituation to the stimulus and the animal deemed "less stressed" and its welfare "better". With a better understanding of the basic biology, altered physiological processes involved in stress adaptability, it would be possible to assess and devise strategies for improving animal welfare.


FIELD: medicine, pharmacy. SUBSTANCE: method involves the use of human or animal (pig) fibrin from blood clot. New aspect: part of fibrin powder from blood clot is dissolved in glycerol at 50 C for 48 hr. Proposed fibrin paste is used for external application. EFFECT: preparing fibrin paste indicated above.


Based on the resource-based theory and taking the particular case of Qiannian Yaozhai in Liannan County,the paper studies the heterogeneity living-culture resources'strategy and its impact on the sustainable competitive advantage of the tourism economy.The research indicates that the ethnic living-culture resources of human,materials and environment are heterogeneity resources.Only by creating such ethnic cultural resources can the ethnic region obtain sustainable competitive advantage in the tourism economy.The paper argues that we must recognize the characteristics of heterogeneity resources when developing ethnic cultural resources.Ethnic cultural resources can only retain a sustainable competitive advantage in the tourism economy when it keeps its unique characteristics and vitality.The conclusion of this paper will provide reference in the decision-making process for the minority regions to obtain the strategic development of culture tourism.


BACKGROUND
Acute myocardial infarction (AMI) treatment requires timely diagnosis and treatment for optimal health outcomes. The COVID-19 pandemic has caused changes in healthcare delivery and utilisation; therefore, our study explored the changes in emergency care quality indicators for patients with AMI before and during different periods of government response to the COVID-19 outbreak in Taiwan.

METHODS
The Taiwan Clinical Performance Indicators (TCPI) database was used to evaluate the impact of COVID-19 on acute care quality indicators for patients with AMI during four periods: before the COVID-19 outbreak (Period I, 1 January to 31 December 2019) and during three periods in which the central government imposed different levels of epidemic prevention and response alerts (Period II, 1 January 2020, to 30 April 2021; Period III, 1 May to 31 July 2021; and Period IV, 1 August to 31 December 2021) .

RESULTS
A 15.9% decrease in monthly emergency department admission for patients with AMI occurred during Period III. The hospital "door-to-electrocardiogram time being <10 min" indicator attainment was significantly lower during Periods III and IV. The attainment of "dual antiplatelet therapy (DAPT) received within 6 hours of emergency department arrival" indicator improved in Period IV, whereas "the primary percutaneous coronary intervention (PCI) being received within 90 min of hospital arrival" indicator significantly decreased during Periods III and IV. The indicator "in-hospital mortality" was unchanged within our study duration.

CONCLUSION
Overall, the quality of care for patients with AMI was mildly influenced during the assessed pandemic periods, especially in terms of door-to- electrocardiogram times of <10 min and primary PCI received within 90 min of hospital arrival (Period III). Using our study results, hospitals can develop strategies regarding care delivery for patients with AMI during a COVID-19 outbreak on the basis of central government alert levels, even during the height of the pandemic.


The results of comparative analysis of the data on sensitivity and specificity of different methods for topical diagnostics of insulinomas are presented. It is concluded that MSCT and intraoperative ultrasound study are the most sensitive and specific methods for this purpose among the non-invasive and invasive techniques, respectively. An optimal algorithm for diagnostics of the tumours is proposed.


THE task of any state is to create a system of state bodies that will be able to function most effectively in order to streamline public relations and recognize a person, his rights and freedoms as the highest value. Such a task is only possible for a properly structured state system of law enforcement agencies. A comparative analysis of the organization of the activities of law enforcement agencies in Russia and China allows us to consider the issues of the identity of law enforcement agencies and the borrowing of international experience in the effective organization of law enforcement activities. Keywords : the Constitution of the Russian Federation, the legal system, law enforcement agencies, law enforcement activities, the People's Republic of China, the Russian Federation.


Abstract The prey-size selection, foraging behavior, and intake rate of overwintering Redshanks (Tringa totanus) were studied in a supratidal-intertidal system with high intertidal densities of shorebirds (100 birds ha−1). For assessing the importance of the energy obtained in the supratidal habitat (saltworks), daily consumption in this habitat was compared with the total daily energy requirement. Redshanks passively select prey within a certain size range from those accessible on the intertidal area. Despite the high prey biomass on the mudflats, Redshanks exhibited a low intake rate during winter (0.321 kJ min−1). This low intake seems to be related to the influence of the high densities of foraging shorebirds on the behavior of prey. Although intake rate was higher in the saltworks, the majority of Redshanks did not choose to feed there in winter. This foraging pattern seems to be related to density-dependent effects in habitat occupancy, as social interactions could have kept Redshanks out of the saltworks in winter according to the predictions of the ideal-despotic model. Energy intake in the supratidal habitat contributed 23% and 82% of the total daily energy requirement in winter and the pre-migration period, respectively. Redshanks were able to meet the total daily energy requirement during the pre-migration period by increasing foraging time in the saltworks. The availability of supratidal foraging habitats seems to contribute significantly to the maintenance of the population of overwintering Redshanks.


Necessity and feasibility analysis of production and research cooperation between research institutes and agricultural enterprises were studied,according to the present situation,through the practice of production and research cooperation in Shandong academy of agricultural sciences,countermeasures of strengthening production and research cooperation were put forward.


Objectives: To investigate the agreement between optical coherence tomography (OCT) and OCT-based angiography (OCT-A) in estimating retinal nerve fiber layer thickness (RNFLT) and evaluate the associations between peripapillary vessel density (VD) and RNFLT measurements obtained with both devices. Materials and Methods: The AngioVue (Optovue Inc., Fremont, CA, USA) and Spectralis (Heidelberg Engineering, Heidelberg, Germany) images of 325 patients were screened retrospectively. RNFLT values were recorded using both devices. The intraclass correlation coefficient (ICC) and Bland-Altman plots were obtained to investigate the agreement between the devices. Age- and intraocular pressure-corrected associations between VD and RNFLT measured by the two devices were analyzed using linear regression models. Results: ICC revealed excellent agreement for global, superior, inferior, and temporal RNFLT and good agreement for the nasal quadrant (ICC=0.895, 0.936, 0.923, 0.887, and 0.614, respectively). The Bland-Altman plots showed poor agreement for all measurements with a large span of limits of agreement and significant proportional bias (p<0.05). VD was found to be strongly associated with the RNFLT measurements of both devices (p<0.001). Conclusion: The disagreement between the devices should be considered in clinical practice, and the data should not be used interchangeably. The association of the peripapillary VD with RNFLT using both devices indicated that RNFLT assessed by the AngioVue could be used in glaucoma management along with VD.


Recognizing human actions is fundamentally a spatio-temporal reasoning problem, and should be, at least to some extent, invariant to the appearance of the human and the objects involved. Motivated by this hypothesis, in this work, we take an object-centric approach to action recognition. Multiple works have studied this setting before, yet it remains unclear (i) how well a carefully crafted, spatio-temporal layout-based method can recognize human actions, and (ii) how, and when, to fuse the information from layout and appearance-based models. The main focus of this paper is compositional/few-shot action recognition, where we advocate the usage of multi-head attention (proven to be effective for spatial reasoning) over spatio-temporal layouts, i.e., configurations of object bounding boxes. We evaluate different schemes to inject video appearance information to the system, and benchmark our approach on background cluttered action recognition. On the Something-Else and Action Genome datasets, we demonstrate (i) how to extend multi-head attention for spatio-temporal layout-based action recognition, (ii) how to improve the performance of appearance-based models by fusion with layout-based models, (iii) that even on non-compositional background-cluttered video datasets, a fusion between layout- and appearance-based models improves the performance.


This report is written in cooperation with the Swedish National Road Administration South-Eastern Region in Jonkoping. The report is a result of the evaluation to give an answer to the question abo ...


Marine natural products have attracted the attention of scientists to isolate novel biologically active metabolites. Several promising metabolites were discovered from marine sponges with different biological activities including antimicrobial and anticancer. By far, more than 36% of the metabolites discovered from marine organisms were isolated from sponges. In this study, the alkaloids isolated from marine sponges with antimicrobial activity were described.


In present study a Java algorithm to calculate degree distribution and detect network type was presented. Some indices, e.g., aggregation index, coefficient of variation, skewness, etc., were first suggested for detecting network type. Network types of some food webs reported in Interaction Web Database were determined using the algorithm. The results showed that the degree of most food webs was power law or exponentially distributed and they were complex networks. Different from classical distribution patterns (bionomial distribution, Poisson distribution, and power law distribution, etc.), both network type and network complexity can be calculated and compared using the indices above. We suggest that they should be used in the network analysis. In addition, we defined E, E=s-ū, where ū and s is mean and variance of degree respectively, as the entropy of network. A more complex network has the larger entropy. If E≤0, the network is a random network and, it is a complex network if E>0.


Nowadays technology has been developed to favor the people by automation process. Image processing is to extract important data from images. Using this extracted information description, interpretation and understanding of the scene can be provided by the machine. Core point of image processing is to modify images in to desired manner. Image processing plays a vital role in various fields like Agriculture, weather reporting, medical purpose and industries, etc. Several image processing approaches are available in real-time. In this paper have charted three approaches: color discovery, object counting, and color separation.


To further increase the energy conversion efficiency of thin-film silicon solar cells, the minimization of reflection losses by effective light trapping is essential. Light trapping is achieved by introducing textured surfaces in the layer stack of a solar cell. The incoming light is scattered at the textured interfaces, the light paths within the absorber layer are enhanced and the chance of absorption rises. This work aims to develop an industrial feasible laser-based process for the texturing of the aluminium-doped zinc oxide (ZnO:Al) layer used as front contact in solar cells. While wet chemical etching of the ZnO:Al is an established process for the texturing, a laser-based process offers higher flexibility and controllability of texture scattering properties. Accordingly, the light trapping can be engineered to fit the needs of a solar cell. Within this work, five laser-based processing techniques are evaluated for their applicability to texture ZnO:Al layers in an industrial environment. The direct writing of textures is capable of producing the right feature sizes and is highly flexible. However, it has strong demands on the experimental setup and requires long processing times. Refocusing the laser light by a particle lens array as well as laser-induced chemical etching also lack the industrial feasibility due to the complex processing setup. The creation of laser-induced periodical surface structures (LIPSS) by ultra-short pulse lasers promises small feature sizes with a simple setup. However, the flexibility of feature sizes and shapes is limited. Only direct laser interference patterning (DLIP) is capable of producing a large variety of adjustable textures with right-sized features while being able to cover large areas in reasonable amounts of time with an industrial feasible processing setup. To further investigate DLIP processing, a highly flexible three-beam interference setup was designed and implemented. Within the setup, the beam properties of the three partial beams can be adjusted completely independently. By controlling power, polarization and angle of incidence of the individual beams, the intensity distribution within the overlapping volume is adjusted. This intensity distribution then translates to a topography on the ZnO:Al sample. With one single laser pulse, hundreds of thousands strictly periodic micrometer and submicrometer-sized features are created. The general geometry of the features can be varied and the spatial periodicity can be adjusted deliberately and continuously. The electrical properties of the ZnO:Al remain nearly unchanged and although there is a minor


Recent research efforts have illustrated the importance of capillarity on the behavior of two-phase flow (gas-liquid) in low Bond number systems; that is, systems where capillary forces are important relative to gravitational forces. Such systems include capillary tubes and microchannels as well as the gas flow channels of a PEM fuel cell. High speed microscopy experiments visualizing air-water flow through a 500 micrometer square glass capillary, 10 cm long were conducted. The flow rates are significant with velocities of 6.2 m/s for the air and 0.2 m/s for the water. A unique annular flow with periodic destabilization of the gas-liquid interface has been observed. Standing waves develop on the liquid film and grow into annular lobes typical of that observed in low speed two-phase flow in capillary tubes. Atypical is the interface destabilization phenomena. The leading face of the lobe will decelerate and suddenly become normal to the wall of the square capillary while the trailing face of the lobe will remain gently sloped back into the annular liquid film. The transition between the leading and trailing faces acquires a sharp edge having a exceptionally large curvature. The entire structure then rapidly collapses and produces travelling waves which propagate upstream and downstream along the annular liquid film. The entire sequence of events takes approximately a half millisecond. This destabilization phenomenon is regular and periodic. Visualization of the destabilization from the high speed microscopy setup and preliminary analysis are presented.Copyright © 2006 by ASME


The significance of periodic limb movements in sleep (PLMS) in the absence of Restless Legs Syndrome (RLS) or Periodic Limb Movement Disorder (PLMD), has been a controversial issue in recent years. Nevertheless, based on evidence gathered in recent years on the associations and consequences of PLMS, the issue needs to be reconsidered.Here it shall be demonstrated, that PLMS are associated with disturbed sleep far beyond the affected individual noticing it, and that they have significant and potentially severe consequences on health, which also extend far beyond subjective sleep impairment. Periodic Limb Movements are Associated Sleep Fragmentation It is well established that PLMS are associated with microarousals and autonomic activation and therefore associated with an alteration in sleep structure. Whereas older concepts assumed that PLMS caused those arousals, more recent studies revealed, that PLMS and arousals are associated in another, more complex and non-unidirectional manner: Arousal equivalents, e.g. delta waves, heart rate increases 1 or other changes in cerebral and autonomic activity 2 can herald PLMS. In the most recent scoring criteria for periodic leg movements (PLM), this has been taken into account and a PLM with an arousal can be scored even if the arousal precedes the onset of a PLM. 3


Mangrove forest was once cut down on a large scale area to use for shrimp culture etc. But now, mangrove reforestation is advanced for the disaster prevention in the coastal area and for increase in production of marine resources. However, reforestation activities are not so going well. Although it is known that the ground level has affected the result of reforestation, the range of exact adaptation is not examined well. When a mangrove area is used for other purposes, the ground level is usually changed. In this paper, in order to estimate the suitable growth condition in Rhizophora apiculata, the relative height in the study area was measured by high precision GPS. Then, the biomass in the area as the index of productivity was calculated using the aerial-photograph taken by radiocontrolled helicopter. Fine satellite imagery is hard to be obtained in a tropical region, and the tidal level at the observation influences analysis for mangrove region. The radio controlled-helicopter can be applied at any time standing by. This is the reason why we used this platform. As a result of the analyzing optimum growth condition in Rhizophora apiculata based on the above-mentioned, it was found that the range of relative height suitable for growing is between 36cm and 95cm.


Coffee: terroirs and qualities is a new, revised and enhanced version of the book "Cafes : terroirs et qualites" published in French in 2003. It is a book of meetings. Meetings between men and women who study coffee growing from different angles: from the viewpoint of human societies who practise it and the lanscapes it shapes, taking a geographical and socio-economic approach; in terms of the plant itself, its cultivation and processing, taking an agronomic and technological approach. This is the meeting between the MOCA group, from the University of Toulouse-Le Mirail, and the CIRAD, a meeting that led to the idea of a book in which those points of view and experiences could be compared, gain mutual enrichment and provide food for thought. Taking concrete examples, it analyses the relation between terroirs and qualities, examines the role of quality in coffee sector revival programmes and examines how the coffee supply chains perform in the face of market realities. It is intended for a broad readership: researchers, students, managers in the coffee supply chain, representatives from producer groups, policy-makers and manufacturers. Foreword: I - Qualities and territories, a reciprocal relationship : The qualities of a coffee (Jean-Jacques Perriot, Fabienne Ribeyre, Christophe Montagnon). Coffee qualities and territories: an historical viewpoint (Benoit Daviron). Coffee and mountains: product quality and territory qualification (Francois Bart). Origin coffees: are Appellations of Origin on the horizon? (Jean-Christophe Galland, Jacques Avelino, Alejandra Larrain, Christophe Montagnon). II - The place of quality in revival policies : Populations, territory and coffee revival on Kilimanjaro (Bernard Charlery de la Masseliere). Coffee in Cuba: State earnings or a source of income for farmers? (Denise Douzant-Rosenfeld). Migratory tradition and promotion of terroirs in Brazil (Pernette Grandjean). A model in crisis: the Federacion Nacional de Cafeteros de Colombia (Jean-Christian Tulet). III - The quest for quality : Burundi, banking on quality (Frederic Descroix). Cameroon: maintaining quality at all costs (Laurien Uwizeyimana). Central America and the Caribbean: varietal improvement for quality (Benoit Bertrand, Herve Etienne, Fabrice Davrieux, Bernard Guyot). Why not Robusta terroirs? (Christophe Montagnon, Thierry Leroy, Ronald Onzima, Magali Dufour). Authors' addresses


National Oceanic and Atmospheric Administration. Airborne Topographic data (LIDAR) of field activity A-2-00-EC in East Coast from 09/20/2000 to 11/02/2000, http://walrus.wr.usgs.gov/infobank/a/a200ec/html/a-2-00-ec.meta.html.


The main industrial utilization of oil shale is to produce shale oil through a retorting process. In order to lower the carrier gas temperature so as to prolong the service life of the carrier gas preheater and to save energy,moderate amount of oxygen was added to the carrier gas in the oil shale retorting process.The retorting process of oil shale under aerobic condition with low-temperature carrier gas was studied.The characteristic via increasing bed temperature in the retorting process was investigated.Gas and liquid products obtained from the retorting process under aerobic condition were compared with that under anaerobic condition.The results show that oxygen content in the carrier gas has a significant effect on the retorting process as temperature increasing.The temperature of oil shale bed can be increased and sustained to a high enough level for retorting process due to the heat generated by the oxidation reaction of oil shale.The oil yield and the main components content of shale oil under aerobic condition is close to those under anaerobic condition although light components and compounds contained O—H bond and C==O bond in shale oil under aerobic condition are little more than those under anaerobic condition.The results obtained from the present work provide a new retorting process of oil shale to produce shale oil,which has a better industrial application potential.


Abstract : This paper is not a political statement, although it contains value-judgments about anti-Islamic rhetoric heard in the 2016 US presidential campaign. There is, however, an unavoidably political element to this paper, since it considers the potential implications of ideas first publicly discussed by candidates competing for the Republican Partys 2016 presidential nomination. While anti-Islamic rhetoric and actions are integral to the scenario described, the characters are fictional and are not analogous to any military or political figure currently in a position of authority or running for office. The political affiliation of the president in the scenario is deliberately unstated. No political party has a monopoly on or immunity from ugly ideas. The Japanese internment, which underpins everything in this paper, was authorized by a Democrat.


The Spectrometer/Telescope for Imaging X-rays (STIX) is a remote sensing instrument on-board the ESA Solar Orbiter spacecraft. STIX is designated to the study of energetic phenomena in solar flares. A Fourier-imaging technique using tungsten grid collimators in front of CdTe pixel detectors is employed, covering the 4 to 150 keV energy range with a full-width-half maximum resolution around 1 keV at low energies. Acrorad CdTe detectors of 1 mm thickness with a planar aluminum Schottky contact are used as basis for a subsequent patterning process into eight large pixels, four small pixels, and a guard ring. The patterning is done by means of microfabrication technologies. The area of the patterned sensor is 10×10 mm2. Test equipment has been developed for selecting the detectors with best performance prior to integration with the read-out system, and for qualification purposes. The set-up allows pixel-based dark current measurements at low temperatures. Pixel dark currents below 60 pA are needed to avoid excess noise in the read-out ASIC. The best pixels show dark currents below 10 pA at 300 V bias and −20 °C. Spectroscopic measurements with 133Ba sources confirm the good performance. This paper briefly explains the mission context of the CdTe detectors and then gives details of the production and testing procedures. Typical results are shown, with emphasis on performance degradation studies from displacement damage by proton irradiation. This is expected to be the dominant degradation mechanism for this application.


The present technical report serves to reinforce the theoretical knowledge studied in class about Ohm's Law, the different types of electric circuits, etc. In each process conducted will be observed comparing the theoretical data arising from calculations on paper, and experimental data performed with the LabVIEW software.
Before working draft RCL circuits alternating current through the LabVIEW software, should begin by the foundation, which is to understand the basics of voltage, electric current, electric resistance, etc. It is elementary to differentiate between connections in series, parallel and mixed.
The processes are explained step by step, answering each of the questions of the ten guidelines drawn work so that everything that has been done in practice is analyzed, and a theoretical foundation and mathematical analysis of each calculation is presented . It will be seen that the theoretical and experimental data are closely related and that both theory and practice are of great importance in the study of this subject.
For the use of LabVIEW great programming experience is required as icons, terms and ideas familiar to students of this area are used, and relies on graphical symbols instead of written language to build applications, it is for this reason we have seen fit to use this software for the development of this project.


There are analyzed the incidence of whooping cough for the period of 1993 - 2016 in Republic of Moldova in this article. 210 from 280 cases of pertussis reported in 2016 and. Specific IgM antibodies of 174 patients were investigated. The epidemic process of pertussis is cyclical, with a period of 3 - 4 years, with a higher incidence in urban areas and in children up to two years, with a tendency to increase the proportion among the patients of school-age children and adults. The decrease in vaccination coverage from 95.4% in 2008 to 89.7% in 2015 led to an increased incidence. From total number of cases, 68.1% were children aged from 0 to 6 years old. The age structure of registered cases in 2016 included: 22.4% under one year old; 44.3% between 1 - 2 years, 27.1% school age children between 7 -17 years and 4.8% adults. A later uptake of medical care was registered, with an average of 10.5 days after onset of the disease, but in age group of children under one year it was 9.6 days. The bases of the diagnosis of whooping cough in 10.7% of cases were clinical data, in 16.2% were clinical - epidemiological data and in 73.1% were laboratory data. Specific IgM antibodies were detected in 77.0 ± 6.4% of patients. Among patients under one year old, 14.9% were under the age of vaccination, 34.0% received from 1 to 3 doses of vaccine, 19.1% are not vaccinated by false contraindications and 27.6% due to refusal. Among patients from the age group of 3-6 years, 56.0% received 3 - 4 doses of vaccine, 18.0% were not vaccinated because of false contraindications and 40.0% due to the failure of the vaccination. From children patients who received a full course of vaccination against pertussis, 25.0% had been vaccinated 1 - 2 years ago and other 25.0% became ill after three or four years after immunization.


Password-based authentication (PBA) remains the most popular form of user authentication on the web despite its long-understood insecurity. Given the deficiencies of PBA, many online services support multi-factor authentication (MFA) and/or risk-based authentication (RBA) to better secure user accounts. The security, usability, and implementations of MFA and RBA have been studied extensively, but attempts to measure their availability among popular web services have lacked breadth. Additionally, no study has analyzed MFA and RBA prevalence together or how the presence of Single-Sign-On (SSO) providers affects the availability of MFA and RBA on the web. In this paper, we present a study of 208 popular sites in the Tranco top 5K that support account creation to understand the availability of MFA and RBA on the web, the additional authentication factors that can be used for MFA and RBA, and how logging into sites through more secure SSO providers changes the landscape of user authentication security. We find that only 42.31% of sites support any form of MFA, and only 22.12% of sites block an obvious account hijacking attempt. Though most sites do not offer MFA or RBA, SSO completely changes the picture. If one were to create an account for each site through an SSO provider that offers MFA and/or RBA, whenever available, 80.29% of sites would have access to MFA and 72.60% of sites would stop an obvious account hijacking attempt. However, this proliferation through SSO comes with a privacy trade-off, as nearly all SSO providers that support MFA and RBA are major third-party trackers.


We were delighted that Professor Martin Ball invited us to guest edit this special edition of Clinical Linguistics & Phonetics on 'Covert Contrasts' in child speech. Although the idea of covert contrasts is not new, there has been renewed interest in the topic recently due to new developments in the methodologies used to uncover these types of contrasts in child speech. These developments are highly significant, in our opinion, because they provide for the first time the potential to identify reliably the presence, and therefore also the prevalence, of covert contrasts in child speech. In this Introduction we briefly define the meaning of the term covert contrasts, outline the importance of the phenomenon, and explain why it is pertinent to bring together research papers on this topic within a special edition at this time. First, what ismeant by the term covert contrast? In essence, these contrasts involve sounds that the child produces differently (acoustically or articulatorily) but are heard and transcribed by listeners with the same phonetic symbol. In the field of child speech, a frequently used methodology for a variety of research and clinical purposes involves transcription-based data, which show extensive neutralisation of phonological contrasts. However, closer examination of neutralised contrasts using an alternative methodology – namely instrumental techniques such as acoustic analysis, electropalatography (EPG), or ultrasound – has provided convincing evidence that children do sometimes produce acoustic or articulatory contrasts that listeners hear as neutralised. These subtle differences in the production of contrasts are called covert because listeners do not readily detect them and therefore they pass unnoticed and unrecorded in transcribed data. Kornfeld (1971) summed up the phenomenon when he said 'adults do not always perceive distinctions that childrenmake' (p. 462) and that 'adults are biased to hear children's speech in terms of their own (adult) distinctions' (p. 462). Although covert contrasts were described nearly 50 years ago, there are surprisingly few research papers that report instrumental data on this topic. This small literature has nevertheless been influential in shaping our understanding of the nature of both typical and atypical speech acquisition as well as informing interventions for children with speech disorders. Taking some illustrative examples, researchers have found evidence that the presence of covert contrasts in children's speech is a positive sign of progress towards their production of an overt adult-like contrast. The presence of covert contrasts in children's speech has also lent support for the view that speech acquisition is a gradual process and that children can be making significant steps in phonetic mastery of the sound system that may not be captured fully in transcription data. In a recent review of evidence about the underlying nature of children's phoneme errors, it has been argued that 'apparent substitutions are actually cases of


We describe two exceptional collision tumors, namely: a 63‐year‐old woman revealing a melanocytic tumor within a trichoblastoma and a 71‐year‐old woman with a squamous cell carcinoma colonized by dendritic cells of a melanoma. Both neoplasms showed two different tumor components with intimate relationship.


Land degradation is the major issue which affect watershed sustainability and following social, economic and environmental of livelihood people. So, early detection of land degradation is necessary for policy-makers to make appropriate decision. In this way, remote sensing method is a candidate choice for assessments and monitoring. In this study, land degradation was assessed using Rain-Use Efficiency (RUE) in the Shazand Watershed, Iran in 1986, 1998, 2008 and 2016. Thus, annual rainfall was calculated using inverse distance weight (IDW), net primary productivity (NPP) were calculated using Landsat images. The results indicated that RUE had increasing and then decreasing trends which were 10.66, 33.77, 20.03 and 9.47 kg C ha-1 yr-1. The results also illustrate that the mean value of RUE in different land uses varied between the irrigated land and orchard that had the highest value and outcrop dominant areas and bareland had the lowest value of RUE among land use categories. It is also established that spatio-temporal analysis of RUE can provide valuable information about the trend of watershed's sustainability over years.


The current control of a Voltage-Source Converter (VSC) requires continuous innovation due to the increasing demands on the permissible level of harmonics in the mains. Nowadays, one of the most used techniques is the resonant control, which can be implemented in various ways, all having in common that they have a theoretical infinite gain at the resonant frequency. Four of those ways are discussed in this paper, comparing their results when applying them to the current control of a VSC. Two of them were originally used to implement the voltage control of a converter and they have now been applied to the current control of a grid-connected power converter. Simulation and experimental results are provided in order to compare their performance in a grid whose harmonic content includes harmonic sixth, analyzing typical control parameters such as settling time, maximum overshoot and steady-state error.


The purpose of this study was to determine which colleges and universities were offering, planning to offer, or considering the possibility of offering the Doctor of Arts degree and/or sixth-year degree programs especially designed to prepare junior college and college teachers. Questionnaires were sent in February 1970 to the graduate deans of the 290 member institutions of the Council of Graduate Schools and to 16 graduate deans of non-member institutions offering programs beyond the Master's degree. Two hundred sixty-seven responded. Though some factors seem to have a negative effect on the development of these programs, the results of the questionnaires indicate that the Doctor of Arts Degree has received wide acceptance in the last few years. Three institutions now offer the Doctor of Arts degree, 4 are planning to institute it in 1970, 10 in 1971, 6 in 1972, another 7 plan to offer it with no date given, and 46 are studying the possibility of offering it. Twenty-seven institutions offer a sixth-year degree program, 10 offer a sixth-year non-degree program, and 17 institutions are planning to offer a sixth-year degree or non-degree program. (AF) r-1 U.S. DEPARTMENT OF HEALTH, EDUCA & WELFARE OFFICE OF EDUCATION THII,-) DOCUMENT HAS St:4N REPRODUC EXACTLY AS RECEIVED FHOM THE PERSON ORGANIZATION ORIGINATING IT. POINTS VIEW OR OPINIONS STATED DO NOT NEC SARILY REPRESENT OFFICIAL OFFICE OF ! CATION POSITION OR POLICY STATUS OF THE DOCTOR OF ARTS AND SIXTH-YEAR. DEGREE AND NON-DEGREE PROGRAMS FOR PREPARING JUNIOR COLLEGE AND COLLEGE TEACHERS Robert H. Koenker CP Ball State University C) Muncie, Indiana CD


Some regular fractal objects can be obtained from a density function, as a product of periodical components. In the optical processing the manipulation of fundamental components of the structures involving this method is very important. We applied the filter operation to each 2D components of the Sierpinski carpet using an opto-digital device and speckle modulated by Young fringes method.


The extended-power spectrum DS has two coproducts and two products, which interact in an intricate way. Given an H∞ ring spectrum E, the resulting algebraic structure on E∗DS0 gives a framework in which to encode information about power operations. (However, we will not study power operations in this paper). Fix a prime p and an integer n > 0. We shall take E to be a suitable completed and extended version of E(n). To be more precise, we let W be the Witt ring of Fpn , and consider the following graded ring: E∗ = W [[u1, . . . , un−1]][u, u −1] The generators uk have degree 0, and u has degree −2. We take u0 = p and un = 1 and uk = 0 for k > n. There is a map BP ∗ −→ E∗ sending vk to u k−1uk. Using this, we define a functor from spectra to E∗-modules by


Recently a new class of instruments, that uses a detector array to measure spectra for multiple points on the ground, has become available. These instruments build up an image by a pushbroom technique. The realization of the maximum potential of these Array Imaging Spectrometers is dependent on the ability to correct pixel to pixel variations in gain, bias, dark current and linearity of the detector array. Residual calibration striping in each band along the temporal axis, is usually the limiting noise source in these sensors, not photon or system electronic noise. Indeed, performance calculations or measurements which do not take this important noise source into account seriously overestimate the performance of Array Imaging Spectrometers. In this paper, the calibration requirements for Array Imaging Spectrometers, in general, and the procedure used to calibrate the Airborne Hyperspectral Imager (AHI) will be discussed. Examples from the Airborne-Hyperspectral Imager (AHI) will be used to illustrate the residual error and characterize its effect.


In the diploma thesis we are dealing with the problem of developing a recommender system for a clothing store based on transaction data. We start with theoretical basics about recommenders and association rules. Afterwards we describe data and represent its quantitative and qualitative aspects. We continue with the detailed explanation of implemented methods, namely, nearest neighbors and matrix factorization. In the end we compare the results of our methods with naive method of recommending most popular products, achieving much better results. Matrix factorization produced the best results and we would use it in production.


The invention relates to a bath safety control system and a bath safety control method. The bath safety control system is electrically coupled to at least one load and includes a power source, at least one safety relay, an operation relay, a processing unit, and a detecting unit. The processing unit determines whether the operation relay has a fault according to whether the detecting unit is activated. When the processing unit determines that the operation relay has the fault, the processing unit controls the at least one safety relay to be turned off. The bath safety control system and the bath safety control method can enhance the protection of the load.


High in omega 3 fatty acids and resistant to bacterial colonization, Kerecis Omega3 offers a novel option for wound healing.


Benzo[a]pyrene (BaP) is a genotoxic carcinogen and a neurotoxicant. The neurotoxicity of BaP is proposed to arise from either genotoxicity leading to neuronal cell death, or perturbed expression of N‐methyl‐d‐aspartate receptor (NMDAR) subunits. To explore these hypotheses, we profiled hippocampal gene expression of adult male Muta™Mouse administered 0, 1, 35, or 70 mg BaP/kg bw per day by oral gavage for 3 days. Transcriptional profiles were examined by RNA‐sequencing (RNA‐seq), DNA microarrays, and real‐time quantitative reverse transcription polymerase chain reaction (RT‐PCR). BaP‐DNA adducts in the cerebellum were quantified by 32P‐post‐labeling to measure genotoxicity. RNA‐seq revealed altered expression of 0, 260, and 219 genes (P‐value < 0.05, fold‐change ≥ ± 1.5) following exposure to the low, medium, and high doses, respectively; 54 genes were confirmed by microarrays. Microarray and RT‐PCR analysis showed increased expression of NMDAR subunits Grina and Grin2a. In contrast, no effects on DNA‐damage response genes were observed despite comparable BaP‐DNA adduct levels in the cerebellum and in the lungs and livers of mice at similar BaP doses in previous studies. The results suggest that DNA‐damage response does not play a major role in BaP‐induced adult neurotoxicity. Meta‐analysis revealed that BaP‐induced transcriptional profiles are highly correlated with those from the hippocampus of transgenic mice exhibiting similar neurotoxicity outcomes to BaP‐exposed mice and rats (i.e., defects in learning and memory). Overall, we suggest that BaP‐induced neurotoxicity is more likely to be a consequence of NMDAR perturbation than genotoxicity, and identify other important genes potentially mediating this adverse outcome. Environ. Mol. Mutagen. 57:350–363, 2016. © 2016 Her Majesty the Queen in Right of Canada. Environmental and Molecular Mutagenesis © 2016 Environmental Mutagen Society.


curation, that can be "a friendly provocation at a time of catastrophes" (p. 290), such as with theARC.HIVE of Contemporary Arab Performing Arts, in "Artivism."The book's final section on "Institutional Reinventions" positions curatorial practice as both a product of "late capitalism" (p. 323) and that which can act as a "decolonial gesture" (p. 340). Here, chapter 33 effectively defines the emergence of the curator within European performing arts, a historical grounding that may have been usefully situated earlier in the publication. Though the book does include welcome international contributions, and more are discovered via notes and references accompanying each chapter, there is an overarching North American-European presence throughout, acknowledged in the "Collective Introduction" as the mutual perspective of the four editors. The inclusion of interconnected researchers allows the reader to witness processes and projects from overlapping perspectives and the combination (or curation) of chapters into sections does draw attention to relevant themes. However, the references in the "Epilogue" to chapters elsewhere in the book could have happened more regularly, particularly where direct overlaps in content or viewpoints are found. As a result, the frequent mention of dance in museum contexts, multiple mentions of the origins of "curate" in Latin root curare, and several mentions of Chantal Mouffe's concept of "agon" or "agonism" obfuscates cohesive conversation. There also are some unfortunate typos, including the misspelling of artists' names and some incorrect page numbers and missed entries in the Index, but overall these are minor issues in what is altogether an impressive publication. Curating Live Arts provides an invaluable opportunity to deepen engagement with the myriad forms of live arts and curation, while offering insights to those interested in performance/dance/theatre/cultural studies, museology, and community arts. This book is an important contemporary resource and a unique opportunity to collectively hear the theorist-practitioners at the forefront of this inventive international movement.


Objective To investigate the current conditions about deep fungal infections in hospital and to provide the evidence to clinical treatment by identification and susceptibility test of 450 strains from fungal infections in target population.Methods Four hundred and fifty strains were isolated with CHRO-Megar medium.Strains were dyed with cotton blue to directly examine under microscopy and combined with being cultured by sahorand medium .The susceptibility test was by Kirby-Bauer methods.Results Among the 450 fungi strains, 396 were Candida Spp. which accounted for 88.0%,and the rest 54 were mould strains which accounted for 12.0%. The resistant rate to fluconazole was (90.15%),to amphotericin B 97.98%,to itraconazole 91.67%,and to flucytosine 89.1%.Conclusion Candida spp.,especially Candida albicans and C.trpoicalis were the most common pathogen in nosocomial fungal infections.


In feminist criminology, there is a growing body of research exploring pathways to prison, but few studies have specifically sought to map women's journeys into the criminal justice system for crimes of physical violence and sex offending. Gender comparative research is sparse, and, to date, we know little about women and men imprisoned in Thailand for these types of crimes. Subsequently, in this paper, we report findings from a gender comparative feminist pathways study conducted in Thailand, with a specific focus on violence and sex offending; namely, homicide, sexual assault, human trafficking, and sex work-related offences. We utilise a qualitative analysis of life-history interviews to centre and value these women's and men's voices, establish their backstories, and thematically map their imprisonment trajectories. Three pathways to prison emerged: (1) lifestyles of contravention, (2) harmed and harming, and (3) destructive masculinity. Utilising the participants' descriptions, we highlight similarities and variance by gender within and between these pathways.


Enterprise architecture for smart cities is the focus of the research project "EADIC - (Developing an Enterprise Architecture for Digital Cities)" which is the context of the reported results in this work. We report in detail the results of a survey we contacted. Using these results we identify important quality and functional requirements for smart cities. Important quality properties include interoperability, usability, security, availability, recoverability and maintainability. We also observe business-related issues such as an apparent uncertainty on who is selling services, the lack of business plan in most cases and uncertainty in commercialization of services. At the software architecture domain we present a conceptual architectural framework based on architectural patterns which address the identified quality requirements. The conceptual framework can be used as a starting point for actual smart cities' projects.


The RF Capacitance-Voltage MOSFET curve extracted from measured S-parameters in the range of ㎓ has been analyzed at high temperatures up to 225℃. It is observed that the voltage shift according to the variation of temperature in the C-V curve is lower than threshold voltage shift. It is also confirmed that the channel capacitance at high gate voltage decreases with increasing temperature.


The effects of pre-chilling (air at −10°C or CO2 snow), freezing method or rate (liquid N2 immersion, CO2 snow and air blast at − 25°C or − 14°C) and frozen storage at − 17°C for 6–9, 24–30, 56–63 or 88–98 days on ground beef patty quality were studied. The patty quality was determined by evaluating color, water-holding capacity (WHC), pH, shrinkage, 2-thiobarbituric acid and textural properties. The liquid N2 immersion freezing resulted in significantly higher cooking and total shrink losses, a paler appearance and lower WHC. A significant reduction was noted in patty quality during frozen storage as indicated by significant increases in storage loss, shear values, hardness, gumminess, chewiness, surface reflectance, and TBA. The CO2 snow pre-chilling provided lower total losses and more intense surface redness.


The question whether a convex closed curve can be approximated by ellipses having a large number of foci is considered. It is shown that the limiting, convex figure of multifocal ellipses may have only one single straight segment. This happens only in the case, when the foci tend partly to infinity and partly to points of the line through the straight segment. The approximations of certain 'distance integrals' are treated; the characterization of approximability remains an open problem.


AbstractExtended, high-resolution (0.23° latitude × 0.31° longitude) simulations with Community Atmosphere Model versions 4 and 5 (CAM4 and CAM5) are examined and compared with results from climate simulations conducted at a more typical resolution of 0.9° latitude × 1.25° longitude. Overall, the simulated climate of the high-resolution experiments is not dramatically better than that of their low-resolution counterparts. Improvements appear primarily where topographic effects may be playing a role, including a substantially improved summertime Indian monsoon simulation in CAM4 at high resolution. Significant sensitivity to resolution is found in simulated precipitation over the southeast United States during winter. Some aspects of the simulated seasonal mean precipitation deteriorate notably at high resolution. Prominent among these is an exacerbated Pacific "double ITCZ" bias in both models. Nevertheless, while large-scale seasonal means are not dramatically better at high resolution, realistic tropica...


As this special issue of Africa Today goes to press, Kenya may have at last taken the first significant steps toward a new constitutional framework to regulate political life. The issue of a new constitution was first raised by political reformers in 1992 following the December 1991 repeal of the section of the constitution that mandated a one-party state. Demands for constitutional reform were voiced again in 1995 by an opposition frustrated with the outcomes of multiparty elections held in December 1992, the country's first such elections in twenty-six years.1 Those elections failed to reestablish legitimate political authority for two reasons: (1) the elections were not contested on a level playing field, but rather one marked by the state's intimidating opposition candidates and their supporters during the year-long run-up to the elections;2 and (2) the constitution's allowing President Daniel arap Moi to be reelected with only 36 percent of the vote, because opposition voters divided their support among three parties that were unable to mount a united challenge to the regime. The results of the 1992 parliamentary elections were similarly frustrating for the electorate and, in the eyes of many Kenyans, even more illegitimate than the 1992 presidential election; candidates of the ruling party, the Kenya African National Union (KANU), won 100 seats (53 percent of seats in the Parliament) with just under 30 percent of the vote. Were it not for gross gerrymandering, coupled with the creation of legislative districts with vastly unequal numbers of voters, the opposition would have gained a parliamentary majority.3 Moreover, in the aftermath of the elections, Moi and the KANU leadership refused to recognize the opposition as the legitimate, albeit fragmented, voice of a substantial majority of Kenyans. Instead of bargaining with its adversaries to establish a modus operandi for Kenyan politics in the multiparty era, the regime behaved as if nothing had changed while pursuing a three-pronged strategy of co-optation, intimidation, and divide and rule. Similarly, the opposition failed to engage the president or to acknowledge that he and his allies were the legitimate voice of roughly one-third of


The greet development about breeding of soybean with high oil from 2000 to 2006 in Heilongjiang was discussed and 49 soybean varieties with high oil have been bred.The average content of oil was 1.75% more that 1991~1999 year.The quality of commodity high oil soybean had reached level of overseas import.Now soybean varieties of high oil were main planting varieties in production,promoted the development of soybean in Heilongjiang and had extension foreground.


A category of geochemical map is used in combination with other data in evaluating oil and gas prospects. There is no standard procedure for compiling such maps. This article presents the principal methodological premises used in compiling geochemical maps of the western part of Central Asia. The purpose of these maps determines their content. They are supposed to reflect the following: 1) conditions of accumulation and transformation of organic matter, which identify these deposits as possible sources of oil; 2) primary dispersion halos of oil (or gas) deposits, whose identification may be useful in the study of the origin of oil fields; and 3) the secondary halos, which constitute direct exploration criteria. To achieve that, the following geochemical points must be taken care of: 1) a qualitative and quantitative analysis of the dispersed organic matter; 2) oxidation-reduction conditions controlling the transformation of organic matter buried in the sediments; 3)present oxidation-reduction status of th...


Abstract : Mercury ions of charge multiplicity up to n = 9 have been formed by repeated collisions of slow electrons (less than 150 eV) with ions trapped in an electron beam of high current density (.05 A/sq cm). Ion current is observed at electron energies below the ionization potential for all multiply charged ions up to n = 8 and is ascribed to collision sequences involving metastable states of the ions (eN/eN(m)/ee(N + 1), where N represents an ion of charge multiplicity n). All the breaks observed in the ionization probability curves for n < or = 3 can be explained in terms of collision sequences involving spectroscopically known metastable levels as limiting steps. Measured ionization potentials of the highly ionized species up to n = 9 are in reasonable agreement with extrapolation of spectroscopic values. (Author)


A possibility of applying the multifractal detrended fluctuation analysis (MF-DFA) to the investigation of the gas-sensitivity dependence on the thin-films surface morphology formed using different technological parameters of annealing has been studied. Methods of analyzing the dynamics of complex systems are modified so as to investigate the structure of the metal-containing polyacrylonitrile (PAN) thin films. The long-range power-law correlation in structure of the studied film surface has been studied. The analysis have showed that the time-temperature annealing modes increasing brings to the Hurst parameter value increasing that points to a long-range power-law correlation in structure of the studied film surface.


Brazilian Supreme Court's Binding Ruling nº 24 has caused a series of unwanted effects in the criminal and criminal procedural treatment of tax crimes. The most recent arises in a discussion about the classification of tax crimes as formal or material offenses in the Brazilian Supreme Court (ADI 4.980) and in the Brazilian Superior Court of Justice (Special Appeal nº 1.982.304). In this article, the authors argue that this classification is irrelevant for the purposes of the application of the Binding Ruling nº 24 as well as for the determination of the initial term of the statute of limitations (art. 111, I, Penal Code).


The invention in particular relates to the installation and / or removal of at least one software module, with centralized constraint solving, in aircraft equipment. After receiving a module list of references software, said list including at least one reference to said at least one software module, and at least one command associated with said at least one reference installation or uninstallation of said at least one software module , constraints are accessed. Access is independent of access to said at least one module. A sequence of elementary operations solving said constraints is then evaluated for applying said at least one command to said at least one reference.


In this curious and learned Volume the Illustrious Author hath with great industry endeavour'd to explain the whole Nature of Comets, their Place, Parallaxes, Distances from the Earth, Beginning and End, the several Appearances of their Heads and Trayns, together with their admirable motion


The invention relates to a spherical wheel (10) for moving a vehicle, and to a vehicle implementing the wheel, wherein the wheel (10) is rotated by a shaft (12) that is rotatable about an axis (14). According to the invention, the wheel (10) includes two hemispherical shells (15, 16), the surfaces of which follow the spherical surface of the wheel (12) and each of which is delimited by a plane (17, 18). The hemispherical shells (15, 16) are each pivotable, via a pivot linkage, relative to the shaft (12), an axis (21, 22) of each of the pivot linkages being perpendicular to the plane (17, 18) of the hemispherical shell (15, 16) in question. The planes (17, 18) delimiting the two hemispherical shells (15, 16) intersect.


Older cast and ductile iron mains, installed bare many years ago to distribute manufactured gas, are reaching the end of their useful life. The author, recommends when to replace the old mains using a numerical form. The numerical form is presented and an applicative example is given.


Objective To investigate the diagnosis significance of serum cystatin C(Cys-C), β2-microglobulin(β2-MG) and creatinine(Cr) in multiple myeloma(MM). Methods The serum levels of Cys-C, β2-MG, Cr, uric acid(UA) and urea of 43 newly diagnosed MM patients and 30 healthy persons in Hainan Nongken Nada Hospital and Nanfang Hospital from February 2010 to January 2014 were detected using Hitachi 7600 automatic biochemical analyzer. Receiver operating characteristic curve(ROC) was used to evaluate the value of Cys-C, β2-MG and Cr in the diagnosis of MM. Results The level of Cys-C in patients with MM(2.06±0.82) mg/L was significantly higher than in the control group(0.71±0.18) mg/L(P 0.01), and it was significant positive correlated with β2-MG(r=0.523, P 0.05). During Durie-Salmon stage, the level of Cys C(3.14±1.38) mg/L in phaseⅢ was significantly higher than that in phaseⅡ(1.35±0.16) mg/L and phaseⅠ(0.97±0.18) mg/L(P 0.01). The levels of serum Cr and β2-MG in phaseⅢ showed statistically significant difference comparing with that in phaseⅠandⅡ(P 0.05). Cys-C level of serum light chain(2.75±1.01) mg/L was significantly higher than that of no secretion(1.49±0.53) mg/L in different immune classification(P 0.05), and β2-MG level of Ig A type serum(7.48±4.52) mg/L was significantly higher than that of no secretion(5.37±2.64) mg/L(P 0.05). Receiver operating characteristic curve analysis showed that area under curve(AUC) and 95% confidence interval of Cys C(0.912, 95%CI: 0.891-0.960) were higher than that of the β2-MG(0.853, 95%CI: 0.821-0.894) and Cr(0.741, 95%CI: 0.702-0.795), the difference was statistically significant(P 0.05). Conclusion Cys-C can be used as one of indexes for the early diagnosis of MM patients with renal damage, which is better than β2-MG and Cr, and it also can help with clinical stage, tumor burden and prognosis.


Using a general Hamiltonian treatment, we theoretically study the generation of degenerate quadrature squeezing in a dual-pumped integrated microring resonator coupled to a waveguide. Considering a dual-pump four-wave mixing configuration in an integrated Si3N4 platform, and following the coupled-mode theory approach, we investigate the effects of parasitic quantum nonlinear optical processes on the generation of squeezed light. Considering five resonance modes in this approach allows us to include the most important four-wave mixing processes involved in such a configuration. We theoretically explore the effects of the pump detunings on different nonlinear processes and show that the effects of some of the parasitic processes are effectively neutralized by symmetrically detuning the two pumps. This yields a significant enhancement in the output squeezing quality without physically changing the structure, but suffers from the trade-off of requiring substantially higher pump power for a fixed target level of squeezing.


: Th is study analyzed the 19 virulence genes (VGs) of 117 Glaesserella (Haemophilus) parasuis (G. parasuis) isolates from the nasal cavities of live piglets from the south of China and assessed the associations between VGs and serovars, sequence types (STs) of these isolates. Th e detection rate of 19 VGs ranged from 1.7% to 95.2%, with vacJ and clpP (95.7%) as the most prevalent. Of the 117 G. parasuis isolates, 105 were assigned to ten distinct serovars (1, 2, 4-10 and 15), and twelve of the isolates tested were non-typable (NT). Th e serovar 10 (17.9%) was the most prevalent. Th e G. parasuis isolates belonging to the same ST and serovar harbored diff erent VGs, and all isolates exhibited considerable genetic heterogeneity. Significant correlations were found between VGs and serovars, diff erent pathogenic serovar groups, and members of clade 2 (based on ST). Th e results complement epidemiological data of G. parasuis and will help the scientific community understand the extreme genetic diversity and pathogenesis of G. parasuis, which will aid in the development of G. parasuis vaccines.


The invention relates to a method for depositing bionic hydroxyapatite (HA) on a zinc phosphate conversion coating surface, which comprises the following steps: preparing a simulated body fluid, in which the solute concentrations are as follows: 8.035-16.07g/L sodium chloride, 0.355-0.71g/L sodium bicarbonate, 0.225-0.45g/L potassium chloride, 0.231-0.462g/L dipotassium hydrogen phosphate dihydrate, 0.311-0.622g/L magnesium chloride hexahydrate, 39-58.5mL/L 1mol/L hydrochloric acid, 0.292-0.584g/L calcium chloride and 0.072-0.144g/L sodium sulfate; and cleaning a stainless steel sample of which the surface is provided with the zinc phosphate chemical conversion coating, putting the cleaned sample into the simulated body fluid, putting in a 36-38 DEG C thermostatic water bath oscillator, immersing for 0.5-30 days, taking out, cleaning with deionized water, and drying to obtain the HA coating. The composite coating is beneficial to enhancing the corrosion resistance of the stainless steel implant, has excellent biological activity, and implements early healing and long-term stability of the stainless steel implant.


Abstract A retrospective observational study to assess whether hormonal treatment (HT) with transdermal estrogens alone or in combination with micronized progesterone increases breast density and to compare these changes to those of a control group of 4120 patients were not given HT. We included 150 patients whose baseline breast density was assessed with photon-counting spectral mammography and 1 year after hormone treatment. The reduction in breast density was compared using an analysis of covariance. The difference in breast density between mammographies in the HT group was −0.40 ± 5.5 and −0.85 ± 4.2 in the control group. The changes in density according to the type of HT, we found that women on treatment with estrogen alone presented a difference of 0.44 ± 5.8, and −1.35 ± 5 (p = 0.13) in women on combined treatment. After adjusting changes in density for age and average number of days between mammographies, we observed a difference of −0.36 95% confidence intervals (CI) [−1.04 to −0.31] in the women on HT and −0.71 95% CI [−1.65 to −0.21] in the control group. No increased breast density was observed in women on HT treatment, nor did we observe an increase according to HT type. The difference in breast density loss was smaller in the HT group versus the control group.


Point clouds which are consisting of points defined in the three-dimensional coordinate system obtained by laser scanners or photogrammetric methods, enable many engineering problems to be solved easily. Some of these problems are surface modeling, restoration of heritage buildings and deformation analysis. Particularly, point clouds created on a large scale of land objects are produced by combining data obtained from different stations. This process, also known as point cloud registration, is the combination of two or more point clouds with the certain geometrical calculations and their matching in the same coordinate system. However, evaluating the point clouds together which are created in different local coordinate systems is one of the important problems in engineering projects. The aim of this study is to apply iterative closest point (ICP) and manual point selection in two different point clouds and to examine the effect of noise filters applied to point clouds on these registration processes. Comparing the relative positional accuracy of the registrated point clouds to reveal the optimal method. In this context, the distance measurement and standard deviations for all the registrated point clouds were calculated and compared. While performing the distance measurements, the local model was defined for the point clouds and its effect on the result was examined. Considering the results obtained, the point cloud in which the ICP method without noise filter was applied and the local model defined and registrated, gave the most optimal result with an average distance of 0.009594 m and a standard deviation of 0.36142 cm.


Politics is a significant factor in determining education policy. Despite efforts to isolate education from the impact of elections, recent research has demonstrated that local, state, and federal elections affect education policy. This article integrates the findings in this volume, posits a set of hypotheses, and traces a research agenda for the study of elections and politics.


To increase safety and reduce costs in maintaining buried pipelines, we have been studying various types of robots capable of inspecting and repairing such pipelines from inside, and we have recently succeeded in developing automatic welding robots to reinforce welds from the inside of a steel pipe with a diameter of 600 mm. It is now within our scope to put it into practical use. This paper presents a general description of three such robots models which we have developed. These robots, designed to travel over more than 100 m in a complex of piping with bends, can do welding to reinforce existing welds. This paper chiefly discusses techniques used in our development to solve the most difficult problems, namely the determination of the most appropriate travelling and welding methods. Through our activities, we have obtained useful findings to further the study of robotic systems for pipeline inspection and repair.


Each year 152,000 people suffer from Stroke in the United Kingdom. 25.5% of these Strokes are caused by Carotid Artery Disease. This project set out to develop the foundations of a stroke risk prediction profile in carotid artery disease patients. The main focus of the project was investigating Carotid Plaque Volume as an alternative indicator for Carotid Endarterectomy. The secondary aim was to establish the various parameters that differ between symptomatic and asymptomatic patient groups. 2D and 3D ultrasound, Transcranial Doppler Monitoring for micro-emboli, antiplatelet resistance testing and patient medical history were all performed as part of the study. Blood samples and carotid plaques removed during carotid endarterectomy surgery were processed for metabolomic, proteomic and histological analysis. 121 Carotid Artery Disease patients were recruited to the study (Symptomatic n = 93, asymptomatic n = 28). Symptomatic patients displayed a significantly larger plaque volume than asymptomatic patients (0.836 (SD � 0.035cm3) vs 0.629 (SD � 0.056cm3), P <0.05), whilst no relationship could be made between carotid plaque volume and degree of stenosis (F(4,87) = 0.3380, P 0.852). There was a general trend of increasing plaque volume correlating with increasing symptom severity, with plaque volume gradually increased from Amaurosis Fugax (0.721 (SD � 0.056cm3), n = 12), to TIA (0.844 (SD � 0.056cm3), n = 43) and again to Stroke (1.041 (SD � 0.118cm3), n = 25). Patients that were resistant to antiplatelet medication displayed generally raised carotid plaque volumes (1.33 SD �0.242) vs 0.817 (SD �0.052), P 0.059). Trace metal analysis showed trends of raised Iron (P <0.05) and copper (P 0.065) levels in symptomatic plaques. Using Linear Regression of correlation, all plaques across both patient groups displayed a close positive correlation between Calcium and Lead (R2 0.7113; p <0.0001), Calcium and Zinc (R2 0.6867; P <0.0001), Calcium and Sodium (R2 0.9499; P <0.0001) and Calcium and Magnesium (R2 0.9736; P <0.0001). Due to time constraints and equipment failure, full ?omic analysis of plaque and blood samples could not be completed. We have provided further evidence for the use of plaque volume as an alternative to stenosis when deciding upon best treatment for carotid artery disease patients. This project has also helped to lay the foundations of a stroke risk prediction profile by determining several key differences between symptomatic and asymptomatic patients.


Adaptive coding faces the following problem: given a collection of source classes such that each class in the collection has non-trivial minimax redundancy rate, can we design a single code which is asymptotically minimax over each class in the collection? In particular, adaptive coding makes sense when there is no universal code on the union of classes in the collection. In this paper, we deal with classes of sources over an infinite alphabet, that are characterized by a dominating envelope. We provide asymptotic equivalents for the redundancy of envelope classes enjoying a regular variation property. We finally construct a computationally efficient online prefix code, which interleaves the encoding of the so-called pattern of the message and the encoding of the dictionary of discovered symbols. This code is shown to be adaptive, within a loglogn factor, over the collection of regularly varying envelope classes. The code is both simpler and less redundant than previously described contenders. In contrast with previous attempts, it also covers the full range of slowly varying envelope classes.


Mucopolysaccharidosis type IIIA (MPS IIIA, Sanfilippo A syndrome) is a single gene (SGSH) childhood onset neurodegenerative disease for which gene therapy is in clinical trial. Theoretically, the transfer of a working gene should enable functional expression of the defective protein and rescue the phenotype when administered before the onset of irreversible disease. Recombinant adeno-associated virus (AAV) is being used as a vehicle for a number of gene therapy applications and the neurotropism of serotype 9 affords utility for monogenetic neurological disorders. In order to assess the efficacy of restoring the underlying biochemistry in the MPS IIIA brain, tail vein injections of self-complementary AAV9 human N-sulphoglucosamine sulphohydrolase (scAAV9.U1A.hSGSH) at 3 x 1013 vg/kg were administered to 6 and 16 week old MPS IIIA mice. Heparan sulphate, GM2 and GM3 gangliosides were cleared from the cortex, hippocampus and sub-cortex with residual storage remaining in the brain stem and cerebellum. SGSH activity increased in the brain of the MPS IIIA treated mice but remained significantly reduced compared with wild-type. Motor activity as assessed in an open field arena, and gait length, improved in MPS IIIA mice treated at both 6 and 16 weeks of age. However, functional assessment of cognition in the water cross maze test, as well as gait width, normalized in mice treated at 6 weeks of age only, with mice treated at 16 weeks performing similarly to untreated MPS IIIA mice.Astrogliosis was reduced in mice treated at 6 and 16 weeks of age compared to untreated MPS IIIA mice. These results demonstrate that the gene product is actively clearing primary heparan sulphate and secondary ganglioside accumulation in MPS IIIA mice but in older mice, neurocognitive impairments remain. This is likely due to secondary downstream consequences of heparan sulphate affecting neurological functions that are not reversible upon substrate clearance.


Abstract Electrical and magnetic function materials have many potential applications. A magnetic and conducting Ni-doped Fe3O4/polypyrrole (PPy) nanocomposite with a core–shell structure was prepared by in situ polymerisation of a pyrrole monomer in an aqueous solution containing a dispersion of Ni-doped Fe3O4 nanoparticles. The structure and properties of Ni-doped Fe3O4/PPy nanocomposites were characterised by X-ray diffraction (XRD), TEM, infrared spectrometry (IR), vibrating sample magnetometry (VSM) and thermogravimetry (TG). The results showed that the Ni-doped Fe3O4 nanoparticles were completely coated by polypyrrole; the resultant Ni-doped Fe3O4/PPy nanocomposites exhibited a good superparamagnetic behaviour and the saturation magnetisation was as high as 25·2 emu g−1 owing to the adoption of Ni-doped Fe3O4 as the magnetic source. In addition, the influences of Ni-doped Fe3O4 content on the electromagnetic properties of resultant nanocomposites were preliminarily investigated.


Flame retarded polyurethane foams(FR-PUF)was synthesized by the use of expandable graphite(EG)as flame retardant.The effect of the quantity and surface treatment of EG on flame retardance and mechanical properties of PUF were studied.The results showed that the presence of EG brought an overall improvement in flame retardance of PUF,the LOI of PUF increased to 27%,with the addition of EG was 30%,but the mechanical properties were decreased clearly.When EG treated by polyvinyl alcohol(PVA)or when the titanate coupling agent were used,the mechanical properties of FR-PUF were improved obviously and the effect of PVA was prior to that of the titanate coupling agent.


The present invention discloses a light emitting diode having a phosphor layer, heat dissipation, the upper edge region of the negative electrode of the LED heat sink above the annular tacky ceramic sheets, ceramic sheets tacky annular ring metal heat sink, an annular metal heat sink a positive electrode provided with an LED, and the heat sink above the key central region of the negative electrode co LED chips LED, the LED chip and wire bonding is through LED, is coated with a phosphor layer between the electrodes on the LED chip, bonding the optical lens the annular metal heat sink, wherein: the surface of the phosphor layer vapor-deposited coating is connected to the heat transfer, the heat transfer fins plated with a metal ring. Phosphor of the present invention may be maintained at a lower working temperature, such that the phosphor has a long service life, and the color temperature does not change, while ensuring LED life.


In studying the rate of disappearance of horse serum and the curves for circulating precipitin in a group of serum-treated patients it was noted that individuals who have severe serum disease are good precipitin formers and that at the time the precipitin in the circulation reaches the crest of its curve or soon thereafter the precipitinogen rapidly disappears from the blood stream. On the other hand in those individuals who after a first administration of foreign serum, show very mild or no symptoms of serum disease little or no precipitin is demonstrable in the patient's serum and the precipitinogen persists in the circulation for a long period. Intermediate types were also encountered. From these results it seemed at least plausible to assume that an important factor in determining the rate of disappearance of the foreign serum from the circulation was an intravascular union of antibody and antigen. That such an assumption is erroneous seems probable from the following experiments: In one series of experiments 12 previously immunized rabbits were injected intravenously with amounts of horse serum (3.00 c.c. or 6.00 c.c.) comparable to the amounts used therapeutically in the group of patients studied. The animals were then bled every second or every third day and the precipitin and precipitinogen in the serum titrated. Six of the animals had a high titer (1:20,000 or higher) of precipitin in the circulation at the time of reinjection, 2 had a moderately high titer, 1 had only traces of precipitin, and 3 had no circulating precipitin. Two of the 3 rabbits with no circulating precipitin had been immunized 10 months previously and at that time had developed a high titer of precipitin which had entirely disappeared before the reinjection.


The so-called no-time dough bread making processes, wherein dough is developed either totally by physical means (mechanical development) or by a combination of chemical and physical means (activated dough development), have certain advantages over conventional processes that require a long bulk fermentation period. One advantage of the mechanical development processes (e.g., the Chorleywood Bread Process) is that the quality of the flour required to produce bread of a specific quality can he somewhat lower (e.g. protein content) than that required by the conventional processes (I). It is primarily this factor that makes the mechanical development processes attractive for the production of bread from composite flours (2). Although the mechanical development breadmaking processes have definite advantages over the conventional processes, their adoption in developing countries has been precluded by the high capital cost of the mixersdevelopers and the general lack of power for their operation. Accordingly, the objective of the present study was to examine various forms of mechanical development to determine if any of them can be operated manually. Of the various mechanical means of dough development known, the sheeting-roll was adopted on the basis of successful preliminary results. The use of sheeting rolls for dough development is not new. It is now known that the success of the dough-brake used in many countries in Central and South America and Africa arises substantially from its mechanical development effect in addition to other beneficial effects. However, so far as the authors are aware, in these countries there has been no attempt to eliminate (or shorten) the long fermentation period by making more effective use of the development effect of sheeting rolls. This article describes a simple, low-power sheeting


Tracing Kierkegaard's reception at the interfaces of anthropology, sociology, and psychology, this chapter focuses on his treatment in key figures such as Max Weber, Ernest Becker, Erich Fromm, Jean Baudrillard, Rene Girard, and Anthony Giddens. The chapter also contemplates Kierkegaard's psychosocial analysis of the relationship between the individual and society, concluding with an exploration of the insider/outsider dimensions of his critiques of modernity's despair and lived Christianity. [Taken from Publisher's Website: http://onlinelibrary.wiley.com]


Objective To study the association between the clustering manifestation of factors as overweight and central obesity,family heredity,immoderate alcohol drinking,tobacco smoking,hyperlipidemia


Introduction: To limit hypoglycemic risk of during postprandial aerobic exercise the importance of reducing prandial insulin dose have been established with exercise starting 90-min after the meal. People with type 1 diabetes also exercise closer or further away of their mealtime and hypoglycemic risk associated with those timings may be different.
 Objective: We aimed to evaluate the effect of two different timings for exercise onset (60-min vs. 120-min post-meal) during moderate intensity exercise.
 Methods: 37 participants (25 M/ 12 F; HbA1c: 7.4 ± 0.9%) received an ultra-rapid insulin dose reduced by 50% and performed 1 hour of continuous moderate intensity exercise (at 60% of VO2peak) started either 60-min (EX60min) or 120-min (EX120min) after breakfast. Venous blood glucose was measured every 10-min during exercise.
 Results: Decrease in blood glucose between exercise onset and nadir (lowest point during exercise) was more important with EX120min (-68.5 ± 43.2 mg/dL, EX60min vs. -75.7 ± 39.6 mg/dL, EX120min, p=0.015). The number of hypoglycemic events during exercise and during recovery (90-min post-exercise) were similar between EX60min and EX120min (3 vs. 4 and 3 vs. 0, respectively). Postprandial glucose excursion before exercise onset was reduced with Ex60min compared to Ex120min.
 Conclusion: For postprandial aerobic exercise, with a reduced insulin meal bolus, hypoglycemic risk is comparable if exercise is started at 60 or 120min after the meal. Guidelines established with exercise starting 90min after the meal can probably be used for earlier or later timing.

 J.Molveau: None. É.Myette-côté: None. S.Tagougui: None. N.Taleb: Consultant; Viatris Inc. E.Heyman: None. C.Suppere: None. R.Rabasa-lhoret: Consultant; Dexcom, Inc., Abbott, Janssen Pharmaceuticals, Inc., Novo Nordisk Canada Inc., Sanofi, Lilly, Tandem Diabetes Care, Inc., Insulet Corporation.


The proved beginning and the ending of logging on winter cutting-areas in an average taiga of Komi Republic. The periods of logging on winter cutting-area are determined. Criteria of technology reliability of logging are given. The technique of the forecast period of logging is given.


ABSTRACT Accurately monitoring the variation of snow cover from remote sensing is vital since it assists in various fields including prediction of floods, control of runoff values, and the ice regime of rivers. Spectral indices methods are traditional ways to realize snow segmentation, including the most common one – the Normalized Difference Snow Index (NDSI), which utilizes the combination of green and short-wave infrared (SWIR) bands. In addition, spectral indices methods heavily depend on the optimal threshold to determine the accuracy, making it time-consuming to find optimal values for different places. Convolutional neural networks ensemble model with DeepLabV3+ was employed as sub-models for snow segmentation using (Sentinel-2), which aims to distinguish clouds and water body from snow. The imagery dataset generated in this article contains sites in global alpine regions such as Tibetan Plateau in China, the Alps in Switzerland, Alaska in the United States, Southern Patagonian Icefield in Chile, Tsylos Provincial Park, Tatsamenie Peak, and Dalton Peak in Canada. To overcome the limitation of DeepLabV3+, which only accepts three channels as input features, and the need to use six features: green, red, blue, near-infraRed, SWIR, and NDSI, 20 three-channel DeepLabV3+ sub-models, were constructed with different combinations of three features and then ensembled together. The proposed ensemble model showed superior performance than benchmark spectral indices method, with mIoU values ranging from 0.8075 to 0.9538 in different test sites. The results of this project contribute to the development of automated snow segmentation tools to assist earth observation applications.


It was only progressively, by confronting their spiritual experience and the cultural conditions of their apostolate, that Ignatius and his companions were led to found a new order and then to recognize the importance of teaching in colleges. This article sets out the different stages of that progressive discovery. It recalls how Ignatius passed from his chivalrous desires to those of service of and in the Church, by attending to the interior experience of the Spiritual Exercises and to their being set down in writing. The experience of liberty and an objectifying putting down in writing were two poles, characteristic of modernity, that formed the main bases for inventing Jesuit colleges. Moreover, they were also bases which supported the writing of the Constitutions of the Society. For the Jesuits of today they remain ever innovative points of reference for discernment.


Tohn Baptist Manuel, cet. 35, admitted with tetanus. The spasms affected nearly all the muscles of the body, but particularly those of the jaw and abdomen, together with those of the back part of the neck. The abdominal muscles became particularly rigid when touched, and any pressure produced a general spasm all over the body; deglutition extremely difficult, so much so, that in drinking auy liquid he appeared


In the early 60-ies among the leading Russian agricultural physicists was discussion about what is agrophysics. A.F. Chudnovsky, outstanding the thermal and agricultural physicist, participated in this discussion. He wrote a book, which sets out his vision of problem (Chudnovsky, 1963). A. F. Chudnovsky clarified that "Like any new science, standing at the crossroads of many interrelated disciplines the agrophysics continues to develop, and its content is still clarified. This situation is largely explained by the fact that there are very many and varied allied sciences, on which it is based". Value of this book for the modern understanding of definition and scope of agrophysics is undoubted.


The delivery of the S/C by the launcher into a Low Earth Orbit (LEO), followed by a series of long duration manoeuvres to guide it to its final operational orbit around L1 is a particular challenge for the signal acquisition. The complexity is explained by the fact that the dispersion of a launcher such as VEGA or Rockot greatly exceeds the 3dB (half-power) beam width of a 15m ESA network antenna in X-band. Furthermore, the S/C is flying over the short duration ground station passes equipped with a Low Gain Antenna of 9 dB gain variation, transmitting telemetry in low power mode and with an altitude varying from 200 to 1600km. The solution found to cope with a large orbit dispersion was to develop an Xband Acquisition Aid (XAA), small diameter antenna (1.2m) covering the full 3σ orbit dispersion area within its half-power beam width. However, such a small antenna is limited in its capability in acquiring a downlink signal. Given the specified LPF 200x1600km LEOP orbit and the S/C launch configuration (low power mode and high data rate), the signal strength received by the XAA is not sufficient to guarantee carrier recovery when the S/C altitude exceeds 630km. It should be noted that the orbit dispersion increases not only as a function of the antenna elevation, but also as a function of flight time. This underlines the necessity to accomplish the spacecraft initial acquisition as soon as possible using the available short station passes. The other issue is that once the 1 st acquisition has succeeded and the orbit is known with enough accuracy, the S/C is brought to its escape orbit to L1 via a sequence of large main engine burns. If the full range of main engine performance 0% to 110%, is considered, this leads to significant time as well as azimuth shift of the acquisition of signal (AOS) location. This paper explains the mitigation measures found to optimize the acquisition of signal under the unfavorable conditions of a tight link budget and high orbit dispersion both after launch injection and each main engine burn.


This research explores the effects of providing on-time automated assessment in a co-located collaborative system for Entity-Relationship design. In addition, students' perceptions about the validity and usefulness of this automated assessment, and its potential for reflection were analyzed. Thirty undergraduate students from computer science participated in the study, a quasi-experimental pre-post test design was conducted. Short quizzes for measuring students' learning performance were used and the perceptions of students were gathered by means of questionnaires. Results showed that on-time assessment positively affected students' learning performance in the study. Finally, students perceived that the system assessment is valid and useful and has the potential to generate mechanisms for reflecting about individual learning and group performance. The study concludes with steps for further research.


A selective and sensitive electrochemical sensor for detecting uric acid (UA) has been developed. The UA electrochemical sensor was made from single-walled carbon nanotubes (SWCNTs), which were coated on the surface of a gold wire electrode using the chemical vapor deposition (CVD) method. The performance of UA electrochemical sensor was characterized using cyclic voltammetry. The obtained calibration curve followed a linear equation, i pa = 132.753 + 1.512c, with R 2 = 0.99597. The LOD and sensitivity of the SWCNTs-modified gold electrode for UA detection obtained were 5.05 nM and 5.240 μ A mm − 2 nM − 1 , respectively. The reaction between the electrode and UA demonstrated the diffusion-controlled behavior. No interference signals from ascorbic acid, glucose and urea were observed during the UA measurements. However, the signal for dopamine appeared in the voltammogram, although it was located at a different potential. Moreover, the dopamine signal disappeared when the measurement was conducted at concentrations of less than 1 mM. These results confirm that SWCNTs-modified gold electrodes are favorable for detecting uric acid.


We report an experimental investigation of recording of slanted fringe holograms in DuPont HRF-800X071-20 photopolymer film under pulse exposure. An initially weak polymerization ability was improved significantly by using incoherent preillumination. The line shape and position of spectral absorbance curves are discussed for a wide range of slant angles.


We determined the spin reorientation transition (SRT) in face-centered-tetragonal (fct) Fe/Cu(001) from out of plane to in plane, as induced by Ni-capping atoms, by observing the magneto-optical Kerr effect. The SRT takes place when the Ni-capping layer thickness exceeds a critical value dcNi, at which point the perpendicular anisotropy of the fct-Fe film becomes equal to the in-plane anisotropy of the Ni-capping layer. We found that dcNi decreases linearly with increasing Fe film thickness. By extrapolating to zero Ni thickness, the "true" critical thickness for the fct-Fe films is estimated to be 4.3 monolayers. This result is very close to the value obtained using Co-capping layers as reported in literature.


Differences in cooking techniques can affect the glycemic level of rice. The aim of this study was to identify the differences in the blood glucose levels of people with DM after consuming rice cooked using either the steamed method or magicom. This study used a pre-experimental design with one group pre-post test with a repeated measure, which was then compared with the difference in fasting glucose levels with a 2-hour post prandial glucose level. The sample consisted of 24 type 2 DM patients. The independent variable was the cooking method and the dependent variable was the blood glucose level. The data collection was conducted using an observation and a questionnaire. The data analysis was done using a paired t test with a significance level of 0.05. The results of the independent sample t-test analysis obtained a value of t = -1.583 and p = 0.128, so there was found to be no significant difference between the fasting blood glucose levels and 2 hours post-prandial. The results of the descriptive comparison analysis showed that there were differences in the glucose levels between consuming rice cooked using either the steamed or magicom method of 18.304 gr / dl with p = 0.128. Rice cooked with the steamed method is more likely not to increase the blood glucose levels than rice cooked with mMagicom. DM patients should consume rice that has not been heated for a long time.

Keywords: Blood Glucose Level, Steam Method, mMagicom, Diabetes Mellitus Tipe 2


Introduced the combination and the principle of economize on energy and formula operation of double-shin facade. According to the theory of transmit heat and convection and radiation, emphasizes some design project of double-skin facade.


The objective of this study was to evaluate the significance of heterotrophic growth in nitrifying biofilm reactors fed only with ammonium as an energy source. The diversity, abundance and spatial distribution of nitrifying bacteria were studied using a combination of molecular tools and mathematical modeling, in two biofilm reactors operated with different hydraulic retention times. The composition and distribution of nitrifying consortia in biofilms were quantified by fluorescence in situ hybridization (FISH) with rRNA-targeted oligonucleotide probes combined with confocal laser scanning microscopy (CLSM) and digital image analysis. Autotrophic and heterotrophic biofilm fractions determined by FISH were compared to the output from a multispecies model that incorporates soluble microbial products (SMP) production/consumption. In reactor R1 (short retention time) nearly 100% of the total bacteria could be identified as either ammonia- or nitrite-oxidizing bacteria by quantitative FISH analyses, while in reactor R2 (long retention time) the identification rate was only 73%, with the rest probably consisting of heterotrophs. Mathematical simulations were performed to evaluate the influence of the hydraulic retention time (HRT), biofilm thickness, and substrate utilization associated SMP production on the growth of heterotrophic bacteria. The model predicts that low HRTs resulted in a lower availability of SMPs leading to purely autotrophic biofilms. These model predictions are consistent with experimental observations. At HRTs that are about an order of magnitude larger than the reciprocal of the net maximum growth rate the majority of the active biomass will grow suspended in the bulk phase rather than in the biofilm.