This paper explores how to effectively increase the testing scenarios for robustness verification of autonomous vehicles by adjusting various traffic scenarios and different severity of quantifiable weather and interference parameters. The automated test and verification tools developed are based on the VTD vehicle simulation platform, which can quickly generate various weather conditions. In addition, considering the camera disturbed by the raindrops on windshield, we develop a faster and more realistic raindrop interference generation methodology, which can quantify the generation of different raindrop size, density, and flow interference, to enhance the realism and diversity of the testing scenarios of autonomous perception system. We demonstrate the usage of the proposed tools to generate the different testing scenarios under various weather conditions and interference. Then, the AI object detection models were tested under the generated testing scenarios to investigate the effect of raindrops on windshield on the robustness of the object detection model. The contribution of this work is to propose an effective simulation-based testing scenario generator to increase the test coverage and shorten the verification time of the robustness test of perception systems.


Teaching and learning the multidisciplinary field of data analytics requires comfort with multiple domains of knowledge, each with its own assumptions, concepts, and skills. Ideally, such teaching will use an overarching framework that transcends and includes all the reference fields. Natural law provides such an all-encompassing framework for a stress-free and sustainable path to continuous learning. Teaching from natural law helps enhance the student's capacity for comprehension and integration of diverse knowledge and skills. This chapter presents seven key natural law principles, along with examples of their applications in teaching data analytics. It also presents V-theory of transcendence as way to connect with natural law within one's own consciousness.


A study was performed to establish the preliminary design of the space shuttle auxiliary power unit. Details of the analysis, optimizations, and design of the components, subsystems and systems are presented.


Prosody has shown to be an important though perhaps underresearched resource interaction participants produce and use to make their face-to-face interaction work. Here we investigate the role of prosody in intraand intercultural communication in situations of institutional differences that are resources for the production of power differences. The corpus was constituted from two large databases: (a) seven years of research in large inner-city school of a major U.S. metropolitan area, where teachers of different cultural backgrounds taught together in different cultural combinations science classes attended by African American students; and (b) an interview study involving two research assistants with 37 research scientists. The data were transcribed using the GAT transcription convention designed for prosodic analysis and analyzed in terms of pitch (F0), speech intensity, and speech rates using the PRAAT software. The use and display of prosodic resources along three major dimensions is reported. (a) Resistance to comply with the standard conversation formats—e.g., during hedging moves—is associated with diverging pitch levels; solidary efforts are associated with special efforts in matching pitch levels, even if these are out of the normal range of the speaker. (b) In situations where new teachers learn to teach in difficult inner-city schools, successful teacher-teacher collaborations are characterized by prosodic expressions that converge over time, which is simultaneously a matching of prosody characteristic of students. (c) Both within and across culture, conflict is both expressed in and accelerated by considerable increases in pitch levels, speech intensities, and speech rates; the resolution of conflict is both expressed in and accelerated by the coordination of pitch levels. These results are discussed in terms of pathos in interaction and the sociology of emotion, conflict, and solidarity.


A simple theoretical model is presented which aimed at determining the slope of the IMF in a cluster of young stars embedded in a cloud of hydrogen. In the model the stellar and gaseous fluxes for this cluster are added and calculations are made for the ratio of line to continuum fluxes and continuum colors as a function of the slope of a power-law IMF and the age of the cluster. Predictions at far ultraviolet wavelengths are included. It is found that a determination of the slope of the IMF is possible if the cluster is older than about 2 x 10 to the 7th years or if the IMF is much steeper than in the solar neighborhood.


Purpose
This study aims to examine the role of devices in assessing the social impact of an organization. The study examines the effects of device and analyst expertise on the contents and conclusions of the report.

Design/methodology/approach
Six impact reports based on the same data from the same organization were compared to each other, to the charity data and to the devices used. Specific attention is paid to the role of the device's sociomaterial form and discursive entanglements.

Findings
The six reports assessed the impact differently from each other and in ways that were consistent with the devices used. The devices performatively reconfigured the charity in impact reports through a series of omissions and misrepresentations which could be traced to the discourses hardwired into the devices themselves. The devices did not simply present the same impact assessment to different audiences or for different purposes, but (mis)represented the charity in specific ways aligned with the discursive entanglements.

Research limitations/implications
The performativity of sociomaterial impact devices has implications for how researchers approach the study of impact measurement.

Practical implications
In this study, faithful adherence to an impact device led to greater omissions and misrepresentations than less expert impact assessments. Analysts should be supported to identify biases in their devices and be aware of sorts of omissions and misrepresentations that may result. Faithful adherence may not be the mark of rigorous analysis.

Originality/value
Performativity of impact measurement devices is explored with a unique data set.


Very few neurological researches are published regarding health effects of global economic crisis. Our aim was to assess the impact of economic recession on frequency and severity of headaches. We also tested if depression, anxiety and experiences associated with crisis, such as unemployment, were reflected in headaches. This is a retrospective observational study in the Emergency setting of tertiary Aeginition Hospital's Neurology Clinic from January 2008 until January 2009 and from January 2010 until January 2012 of Greek population. Demographic data were collected of 1094 consecutive adult patients with headache. Multinomial logistic regression performed to examine if HAD (hospital anxiety depression), HAD anxiety, experience of serious life events, year of survey had influence on type of headache. The number of headache cases increased significantly from 2008 to 2011 (188 cases for 2008, 233 cases for 2010 and 673 for 2011). The most common type of headache, overtime, was tension type headache, 42.6% for 2008, 39.5% for 2010, 43.7% for 2011), being followed by migraines for 2008 and 2011 (36.2%, 21.1%) and NOS (not otherwise specified) for 2010 (24.9%). The chi-square test showed significant relationship between type of headache and year, as well type of medication and year (p < 0.05). Common analgesics were the most common medication being increased five times during survey period (from 77% in 2008 to 87,6% in 2011). Multivariate analysis revealed stronger association for experience serious events with NOS headaches vs. tension type headache (Odds Ratio OR 0.13; 95% confidence interval CI 0.03, 0,7). This is the first study showing that the prolonged economic crisis affected headache frequency accompanied by a higher use of analgesics.


This report describes a new technique for calculating the spectrum space used by existing frequency assignments. The Spectrum Use Measure (SUM) model determines the amount of spectrum used at a given location or the probability that a given location is unavailable for a new assignment. These quantities, stored in a SUM data base, can be used to produce maps, histograms and indices of spectrum use. The SUM technique has been effectively applied to the 17101850 MHz and the 7750-7900 MHz bands. The report concludes that the SUM technique is an effective indicator of spectrum use and recommends that it should be used when evaluating service bands.


Infrared grating spectra of gaseous GeH3CCH and GeD3CCH were obtained over the 4000‐to−140‐cm−1 region, and the fundamentals of both molecules were completely assigned using a C3v symmetry model. Q‐branch structure was resolved for three of the five perpendicular bands of GeH3CCH, and values for all five Coriolis coupling constants were obtained from analysis or from the zeta sum rule. Anomalous band structure was observed for the C≡C stretching mode, similar to that reported for other monosubstituted acetylenes. A strong rotational perturbation was also observed in the degenerate GeH3 deformation mode which was interpreted as arising from a second‐order Coriolis interaction.


A gas chromatographic method to monitor halofenate, a hypolipemic agent, provided an accurate means for studying its pharmacokinetics, the correlation of plasma level with pharmacologic effect, and estimation of patient compliance. In double‐blind studies, data on interval sampies showed: (1) plasma half‐life about 2 days; (2) almost complete plasma protein binding of the free acid after oral administration of the ester; (3) very low clearance rate; (4) long duration in over 85% of patients. A once‐a‐day schedule is, therefore, feasible with plasma levels being adequate even if the patient skips a day or more of medication. Cood correlation was demonstrated between total halofenate and triglyceride or urate lowering, but not with cholesterollowering.


An integrated and reproducible chemical process was developed to fabricate the N-doped mesoporous carbon by using melamine resin as nitrogen source. A two-dimensional carbon framework of graphene sheets was also used as a conductive substrate in order to boost the performance of such nitrogen-doped carbon materials. Compared with the pure mesoporous carbon, the as-made nitrogen-doped carbon/graphene electrode materials exhibited suitable pore size distribution, ordered meso-structure, and uniformly dispersed N atoms with tunable doping amount. These unique properties make them promising electrodes for supercapacitors with superior performance. In particular, N-doped carbon and decorated graphene electrodes could deliver the specific capacitance of 238 and 289 F/g at the current density of 0.2 A/g in a three-electrode system. The results from symmetrical two-electrode revealed that the highly N-doped carbon electrodes offered excellent rate capability (ca. 78% retention as the current density increased fro...


The present study aims to study the application of one of the strategic planning tools, the BCG Matrix, in the context of a small company in the food business. Studies show that strategic structuring is important and that this, in general, is a poor point in microenterprises due to the complexity, the size of the enterprise and the lack of information. The literature shows that a way of understanding the company and help in the strategic structuring is to use the BCG Matrix, also known as Growth-Participation Matrix, but due to its complexity and the need for information, is poorly applied to micro-enterprises and, therefore,
was applied in the reality of the organization, so that it could become possible to understand its results in the face of the current competitive scenario in which the studied company is. The study was conducted on the basis of a qualitative and exploratory approach, performed through interviews, collection and analysis of historical data and participant observation held during visits to the company. The application of the matrix had as objective the analysis of the products offered by the company to determine the viability of its production. As a result, it is observed that the application of the BCG Matrix can assist in portfolio management also of micro-enterprises by indicating analyses that help the company to decide based on data that justifies its choices. This study also evidences the importance of strategic planning as a basis and direction to make the decisions.


It is said that in grain there is a certain action that interferes with the bone calcification of young animals which is thought to be phytic-acid.However, there has been no report made on the effects of phytic-acid of rice on the calcification of tooth.In view of this, experiments were performed to see how phytic-acid in rice effected the histological changes in the calcification of rat tooth and the interference with Ca-absorption by the mucous membrane of rat intestine, with special references to the effects of the ratio of Ca/P on the calcification of tooth and the condition of Ca-absorption.1) When polished or unpolished rice was used as basic feed, it was found that the calcification of rat tooth was better in the case of the former than the latter.2) When sodium-phosphate or sodium-phytate which was extracted from rice-bran was used as an additive for the feed, the interference with the calcification of tooth was found to be more severe in the latter case. 3) When fed on low Ca and high P feed, the degree of interference with the tooth calcification and Ca-absorption by phytic-acid was severe, but in each case the addition of Ca or V.D of proper consistency to the feed, greatly improved this situation.


Abstract The Z-Zn Mg Sm ternary phase has been studied by electron diffraction. Y 6 3 and the rare-earth elements with atomic radii just below that of Sm in Zn Mg RE 6 3 alloys (RE rare earth or Y) form the icosahedral phase, while with Sm it forms the Z phase. The Z phase is hexagonal with a = 12.4 A and c = 8.8 A, and with the space group P 6 / mmc . The relationship of this phase to the icosahedral 3 quasicrystal is demonstrated through diffraction features. It is shown that this hexagonal phase consists of three icosahedral units rotated by 120o about a common twofold axis, forming the sixfold axis. The similarity of this hexagonal phase to the hexagonal quasicrystal is shown.


The term cyberspace originally appeared in the book Neuromancer by William Gibson, during the decade of the eighties in the bosom of science fiction, to refer "to the conceptual space where words, human relationships, data, wealth and power are manifest by people who use the technology of "Computer mediated communications" -CMC (Rheingold 1996 p.6). Under a significance of consensual hallucination or virtual reality (Misseri L. 2016) created in an unreal space by humans, distant from the social daily cortex.
However, this attribution of virtual generated two effects. In the first place, it gradually displaced the network and the respective interaction experiences to a dichotomy and philosophical debate about considering them as real or unreal. In other words, if the actions executed in digital environments are only abstractions or can be contemplated as well as the diversity of phenomena and social configurations of tangible contact, communication and integration. Second, it was also relegated to political issues within the tension between the conceptions of internet freedom, the intervention of the State (as a regulating entity of social and territorial life) and the possibility of action by other non-state actors for regulation and control of the internet, without it losing its essence, considering it, as well as another abstract territorial space.
Therefore, the purpose of this research is to determine how international and globalized power processes are interpreted and interfere in domestic and cross-border political actions, during 2010 to 2018, for the specific case of child pornography in digital environments, in Colombia. The study was developed through the understanding of the academic positions of internet governability, Onuf's constructivist approaches to international relations and the Process Tracing method for the testing of theories.


Abstract : Why GAO Did This Study.DOD reports that between 2005 and 2013, the number of individuals who received mental health care through DODs MHS grew by 32 percent. MHS mental health care is provided free to active duty servicemembers. Reservists and DOD civilians are eligible for MHS care under certain circumstances.The National Defense AuthorizationAct for Fiscal Year 2015 contains a provision for GAO to assess the availability and accessibility of mental health care in DODs MHS for military servicemembers. This report examines, among other things, (1) the mental health care DOD makes available to servicemembers domestically and overseas and (2) the accessibility of mental health care provided to servicemembers domestically and overseas. GAO analyzed recent, available data on MHS mental health utilization, staffing, and appointment access and compared access data to relevant DOD standards. GAO reviewed mental health data from several DOD surveys as well as documents related to MHS mental health care. GAO also interviewed DOD and service officials and representatives from servicemember and provider associations.What GAO Recommends.GAO recommends that DOD establish an access standard for mental health follow-up appointments and regularly monitor data on these appointments. DOD concurred with GAOs recommendation.


What does the physician do if a noncommunicative long-term care patient, dependent on life-augmenting or support mechanisms, has provided advance directions to cease these treatments under defined circumstances. Must the physician comply, even if the meaning of the directive may not reflect exactly the existing clinical situation? What if the directive is vague and terms like "vegetable" or "non-heroic" or "quality of life" were used by the patient, in the belief that such terms are precise enough for physicians and surrogates?2,12 What if the clinical situation appears to reflect the directive, but the physician feels unable to carry it out because it would result in death, which would conflict with personal, religious, or professional beliefs? The Canadian and American Medical Associations' ethical codes allow for the transfer of physician responsibility under such circumstances. This begs the question. What is the physician's ethical and professional responsibility when personal beliefs conflict with those of a patient if the requested act is legal and conforms to clinical standards? Can the physician rightfully ignore the patient's expressed wishes as directed in a living will? Would the physician ignore the same requests if they were made directly by the patient rather than being contained in a living will ?6,16.17 The critical question is, whose beliefs or wishes take precedence? Do physicians have a moral and professional right to not comply with an advance directive if death might result? Even if the physician has an option to transfer care, it is critical that physicians and medical organizations clarify ultimate decisional responsibility and compliance in extreme cases, even if, in practice, alternative solutions may be found. Perhaps physicians should be obligated to inform patients and surrogates whether they will comply with living will instructions when clinical responsibility is assumed. At that point, another physician might be found. It does not answer the critical moral question, but it does help avoid decisional conflicts. It is only if these issues are addressed, and possible resolutions found, that patients, their families, and the medical profession will feel secure that advance directives have meaning and all parties understand the framework within which the patient's autonomy will be respected.3•7-I O As a society, we must guard against cavalier attitudes toward life when apparent "usefulness" or "quality" appear to be more valued than life's intrinsic sanctity. Physicians must guard against arguments of resource allocation taking precedence over respect for life. But we must also protect ourselves and our patients from the unrealistic expectation that in the technological marvels of medicine is the hope of prolonging a life which no longer captures its essence and is a charade of its meaning." Proper use and respect for living wills may help achieve this goal.


Objective: To explore National Survey of Drug Information Centers practice in Saudi Arabia: With emphasis on Medication-Use Evaluation system at Ministry of Health hospitals in Saudi Arabia.
Methods: It is a cross-sectional four months national survey of drug information services at MOH. It contained ten domains with 181 questions designed by the authors. It derived from Internal Pharmaceutical Federation (FIP), American Society of Health-System Pharmacists best practice guidelines. This survey distributed to forty hospital pharmacies that run drug information services. In this study, the domain Medication-Use Evaluation System explored and analyzed. It consisted of eight questions about the written policy and procedure and application methods for Medication-Use Evaluation system in the drug information centers. All analysis is done through survey monkey system.
Results: The survey distributed to forty-five of hospitals, the response rate, was 40 (88.88%) hospitals. Of those, developedscreening mechanism (indicators) for comprehensive surveillance of the medications use system existed in 24 (60%) hospitals involved 25%-100% the elements. Establish criteria, guidelines, treatment protocols and standards of care for specific medications and medications use processes found in 26 (65%) hospitals applied 25%-100% the elements. Establish mechanisms for timely communication among health-care professionals exist in 23 (57.5%) hospitals found used 25%-100% the elements. Initiate the use of MUE criteria, guidelines, treatment protocols and standards of care in the medication-use process exist in 24 (60%) hospitals found applied 25%-100% the elements. Regularly assesses the effectiveness of the MUE process itself and makes needed improvements exist in 24 (60%) hospitals found used 25%-100% the elements.
Conclusion: There was an inadequate implementation of Medication-Use Evaluation in drug information centers practice. Establishing strategic planning for Medication-Use Evaluation system, choosing the high-cost and high-risk medications and educate drug information pharmacist. It improves Medication-Use Evaluation practice, prevents misuse of medicines, prevents drug misadventure and avoids the unnecessary additional cost.


NPPE imaging findings were reported to show a preferential central and nondependent distribution. However, in our case, NPPE showed a peripheral accent pattern, resembling the ARDS pattern of COVID‐19 pneumonia 4 months ago. Capillary damage from COVID‐19 might still exist.


Purpose – The purpose of this paper is to present a method for solving nonlinear integral equations of the second and third kind.Design/methodology/approach – The method converts the nonlinear integral equation into a system of nonlinear equations. By solving the system, the solution can be determined. Comparing the methodology with some known techniques shows that the present approach is simple, easy to use, and highly accurate.Findings – The proposed technique allows the authors to obtain an approximate solution in a series form. Test problems are given to illustrate the pertinent features of the method. The accuracy of the numerical results indicates that the technique is efficient and well‐suited for solving nonlinear integral equations.Originality/value – The present approach provides a reliable technique that avoids the difficulties and massive computational work if compared with the traditional techniques and does not require discretization in order to find solutions to the given problems.


In order to study the effect of supplementary irrigation and different plant densities on grain yield and yield components of chickpea cv Hashem, an experiment was conducted as split plot arrangement in a randomized complete block design with three replications in Sirvan, Ilam during 2008-2009 cropping season. Main plot included supplementary irrigation (check as non-irrigation, supplementary irrigation at flowering and podding stages) and subplot included plant density (20, 30, 40, 50 plant.m-2). The results showed that supplementary irrigation had significant effect on plant height, number of sub branch, number of pod per plant, 1000-grain weight, protein content, grain yield and biological yield. The highest grain yield (1504 kg.ha-1) was obtained from supplementary irrigation at flowering and the lowest grain yield (613 kg.ha-1) Observed from check treatment respectively. Plant density had significant effect on studied traits expect protein content and harvest index. The highest grain yield was obtained from 50 plant.m-2 and the lowest obtained from 20 plant.m-2 respectively; but there was not significant difference between 40 and 50 plant.m-2. Interaction effect of supplementary irrigation and plant density was significant on number of main branch, number of pod per plant, grain yield and biological yield. The highest grain yield (2006 kg.ha-1) was obtained from supplementary irrigation at flowering stage and 50 plant.m-2 and the lowest grain yield (488 kg.ha-1) observed from check treatment and 20 plant.m-2, respectively.


The Booster for the National Synchrotron Light Source electron storage rings is a 100-700 MeV synchrotron with 28.35 meter circumference. Its design current is 20 mA and its repetition rate is 1 Hertz. The lattice consists of four superperiods, each containing two focusing quadrupole magnets and two defocusing bending magnets. Nominal tunes are Vx=2.42, vy=1.37. Small values of ßx and ¿x in the bending magnets allow a damped emittance ¿x= 5.6xl0-8 meter radians. Details of the lattice, beam dynamics and beam injection and ejection are presented.


SARS-CoV-2, the virus that causes COVID-19, originally was transmitted from animals (likely bats) to humans. And humans can transmit the virus to cats


OA30.05

Background: To assess the ability of immunogens to elicit broadly neutralizing antibodies (bNAbs) against HIV-1, an appropriate animal model is necessary. It has been previously established that the CCR5-tropic SHIV-AD8-EO molecular clone is a pathogenic and mucosally transmissible virus in Rhesus macaques. Furthermore, some macaques infected with this SHIV develop bNAbs; however the mechanism of eliciting bNabs in this model remains unclear.

Methods: One macaque, JG7, slowly developed breadth on a multi-clade 21-virus panel from weeks 47–131 post-infection. Frequency of antigen-specific germinal center B cells and T-follicular helper (TFH) cells were evaluated at the early wk47 time-point as well as somatic hypermutation in these B cell receptors (BCRs). Monoclonal antibodies were isolated and characterized by ELISA binding and neutralization profile.

Results: By wk47, JG7 had high viral load, and high levels of antigen-specific TFH and IgG+B cells in the germinal center. A fingerprint analysis of sera neutralization data suggested a CD4-induced (CD4i) specificity at the early wk47 time-point. BCR sequencing revealed a large clonal family distinguished by high V-gene mutation frequency and long heavy chain CDR3s of 31 amino acids. Four BCRs were cloned and found to recapitulate most of the serum breadth at this time. Furthermore, these monoclonals competed with 17b for binding to gp120 and had enhanced neutralization activity in the presence of soluble CD4, confirming the CD4i prediction.

Conclusions: Our findings support the hypothesis that in the presence of high antigen levels and T cell help, Rhesus macaques can develop cross-neutralizing anti-HIV antibodies with high levels of mutation and long CDRH3s akin to bNAbs isolated from HIV infected humans. These data highlight the utility of the SHIV model for studying development of bNAbs in Rhesus macaques.


In this paper discourse segments are defined and a method for discourse segmentation primarily based on abduction of temporal relations between segments is proposed. This method is precise and computationally feasible and is supported by previous work in the area of temporal anaphora resolution.


As much as Twitter played a major role in political discourse during the 2012 US presidential election, it also served as a conduit for unsubstantiated rumors and misinformation. Based on large-scale content analyzed Twitter messages (n=330,538), our exploratory analyses reveal that rumors about presidential candidates were mainly spread through a retweet button, yet hardly contested and corrected in a interactive process. Twitter showed a strong partisan structure for active rumor spreaders. However, rumor debunkers neither formed a cohesive community, nor exhibited a partisan structure. We found mixed results for the effects of rumor debunking effort. Professional rumor debunking sites (e.g., Factcheck.org) were relatively effective in curbing spread of satire-based rumors, but did not show significant influence on other types of rumors. Implications for the affordances of Twitter and effective rumor debunking strategies are discussed.


Let n be a positive integer.Let IOn denote the semigroup generated by the compound operation of order-preserving partial injective transformation on Xn={1,2,…,n}.This paper described all endomorphisms on IOn.


Marathi is a language spoken predominantly in the state of Maharashtra, India and has close to 70 million native speakers. It is based on the Devanagiri script, which the script used for the mother of all Indic languages, Sanskrit. Devanagiri consists of 46 phonemes and arranges them in a scientific manner based on the process of generation. The consonants are arranged in varnas (classes), and each varna has a unique place of articulation. This work focuses on identifying individual class variants of the first five varnas of the Marathi Devanagiri script.


Background: Cancer patients receiving chemotherapy have a high risk of malnutrition due to both the disease and treatment, and degree of malnutrition is depending on tumour subtype, location, staging and treatment strategy. Early nutritional assessment can identify problems to help patients increase or maintain weight, improve their response to treatment, and reduce complications. This study aimed to determine the nutritional status of patients receiving chemotherapy. A prospective study was conducted among 30 subjects diagnosed with cancer of various sites Methods: and scheduled for three cycles of induction or adjuvant chemotherapy. Nutritional status of each subject was assessed based on nutritional parameters i.e. Anthropometric [BMI, MAMC, TSF, and MAC] and Biochemical [(Haemoglobin, Serum electrolytes and Albumin)] measurements before the initiation of chemotherapy, and follow-up assessment was performed on the completion of third cycle of chemotherapy. In this study it has been found that 95% of Results: subjects suffered from weight loss post chemotherapy. The't' test showed a significant decrease in TSF [t=4.8(p<0.01)], MAC [t=5.94 (p<0.01)] and MAMC, t=5.34(p<0.01) before and after 3 cycles of chemotherapy. The Conclusion: nutritional status assessment is very important in each patient at the beginning and during the treatment. The cancer patients are at high risk of malnutrition and the comorbidities associated with it.


As the operating time of a power plant approaches its design life, the characteristics of crack initiation and growth in thick-section boiler components becomes major concerns. But few data have been reported for long term served materials because it is very difficult to acquire that. In this study, the characteristics of the crack growth behavior of used 1Cr-0.5Mo steel which was served for a boiler header for 30 years and heat-treated 1Cr-0.5Mo steel were studied experimentally by performing fatigue crack growth tests at 538°C and room temperature under triangular and trapezoidal wave-shapes. In order to evaluate hold time effect at elevated temperature, the results of fatigue test with 10 seconds hold time (0.083 Hz) were compared with the results of fatigue test with triangular wave-shapes (0.5Hz). As frequency decreased, the fatigue-crack growth rate showed a significant increase at high temperature. In the case of fatigue test with hold time, the rates of fatigue crack propagation were faster than those in the results of fatigue test without hold time. Finally, fatigue crack growth rates of reheat-treated material were slower than those of long term served material. And the behavior could be characterized by stress intensity factor range.


Magema M. Fuze emerges from this exceptional study as a far more interesting and thoughtful character than modern scholars have imagined. The very circumstances that propelled him into the public eye in the 1860s and 1870s ensured that he would be underrated as an independent thinker. Anglican Bishop J.W. Colenso during the early, evangelical phase of his career enrolled Fuze as a student in his short-lived experiment in elite education, Ekukhanyeni School. After the school fizzled out due to Colenso's financial problems and loss of interest, Fuze stayed on as the bishop's printer. From time to time Colenso wheeled him out as an "authentic" voice of Zulu public opinion. Miraculously, Fuze's views always ran parallel to the bishopâ??s current enthusiasms. After his death, Fuze continued in the employment of the Colenso daughters, Harriette and Agnes, who dedicated their lives to the bishop's last cause: justice for the Zulu royal house. In this capacity he accompanied Dinuzulu during his exile on the island of St. Helena. Up to this point Fuze's public life may be regarded as a textbook example of colonial ventriloquism; he was ever the loyal subaltern whose black skin and Zulu speech could be invoked in support of the Colensos' positions on current affairs.


The pea moth Cydia nigricana Fabricius (Lepidoptera: Tortricidae) has developed to an important pest in pea growing areas (green and grain peas) causing high economic damage. Currently no effective pest control options are available under organic farming conditions. The presented project aims to generate a first draft of pea moth control in organic farming including a risk assessment of pea moth damage incidence and a direct control approach.
Data collection for risk evaluation were arranged for three years (2006 – 2008) in two exemplary pea growing areas in Germany (North Hessen and Central Sachsen). In a small plot experiment in Northern Hessen the combined effect of a pyrethroid product (Spruzit-Neu®, W. Neudorff GmbH KG, Emmerthal, Germany) and different sowing dates using three common green pea cultivars (Avola, Deltafon, Ambassador) on C. nigricana were investigated.
In 2006, the coincidence avoidance of flowering pea plants and flight activity of C. nigricana via alternative sowing dates resulted in reduced pea moth infestation. The pyrethroid showed significant pea moth reduction using early sowing dates (Avola, Deltafon). However, the results have to be confirmed in continuative experiments in 2007 and 2008.


Studies of the prairie by the writer and Fitzpatrick during 1922-33 were both extensive and intensive. They were extensive in that they included an area of 60,000 sq. mi. in western Iowa, eastern Nebraska and portions of the four adjoining states. They were intensive in that a record of the kinds and distribution of grasses, the abundance and relative importance of forbs, and other pertinent data were ascertained and recorded separately for each of 135 selected areas. Since most of these prairies were examined two or more times each growing season, and many repeatedly during a five-year period, a clear, concise description of each was secured. In this study it soon became clear that the vegetation receiving an annual rainfall of 30-32 in. was better developed in many ways than that in the drier areas westward and northward with 25-29 in. mean annual precipitation. Some of these differences were pointed out by Weaver avid Fitzpatrick (1932. 1934) but the prairie was considered in its entirety and space did not permit descriptions of individual prairies. Further studies of the prairie as affected by the great drought of the 1930's (Weaver and Albertson 1936, 1944) and the history of their degeneration under grazing (Weaver and Hansen 1941 ) emphasized the importance of the isohyet of 32 in. as marking the place of beginning of rapid change from the mesic prairies of southwestern Iowa to the more xeric ones northward and westward. During the first quarter of the present century prairie hay for horses was still in considerable demand. But this was rapidly decreased with the general use of the automobile and especially the farm tractor. Not only did the need for hay decrease, but also the prairie was readily broken by use of plow and tractor. Moreover, the farmer could now easily cultivate his expanding fields of maize. Several fine remaining Iowa prairies some of 80 or more acres were broken during our earlier study and many others since that time. Indeed, it seems that all will vanish (Hayden 1946). Therefore it was decided to write the description of a typical tract of wellwatered Iowa prairie that was visited many times (luring and since 1929. Names of grasses are according to Hitchcock and Chase (1950) revised Manual of the Grasses of the United States. Other scientific names follow Gleason's (1.952) New Britton and Brown Illustrated Flora.


Objective:For the investigation of nurse practitioner of sharp injuries in Yueyang.Methods:Using stratified random sampling and multi-stage 195 nurses of different levels of hospital in yueyang were surveyed.Results:There were non-significance difference of Sharp injuries in ages,titles,seniority,work departments,and hospital level comparable in nearly three months(p0.05).47.5%nurses have sharp instrument injury at least once,55.3%nurses beliere the injury is due to his careless handling,only 4.6%correctly handle and report.Sharp instrument injury occurrence are concerned with returning the needle cap sleeve to the used needle and wearing gloves.Conclusion:We should strengthen occupational safety education,formulate disposal and report measures,in order to ensure the nurse in a safe environment.


Forestry is of fundamental importance for sustainable production in watersheds in the Atlantic Forest. Long cycle crops contribute to soil preservation due to the small number of operations throughout the cycle. The forestry promotion carried out by large companies in the sector provides technical and operational support to rural producers who wish to enter silvicultural activity. In this sense, the mapping of economically viable areas for the implementation of a forest plantation supports the planning and guarantee of profitability to the rural producer. This paper presents a methodology to obtain the net present value (NPV) distributed spatially along a river basin in the function of the local productivity and the costs of implantation, maintenance, and extraction of the wood. The results show that the mapping of NPV determined the economically viable areas for forestry projects along a river basin and the use of basilar geoprocessing for sustainability.


Abstract Far-infrared Fourier transform magnetotransmission spectroscopy has been carried out on two GaAs/Al0.3Ga0.7As multiple-quantum-well (MQW) samples with δ-doped Si donors located away from the well centers. Temperature and magnetic field dependence studies have been used to identify the features in the spectra. In contrast to well-center D−ions, the off-well-center D−singlet binding energy decreases with increasing magnetic field between 5.5 T and 15 T as reflected by the decreasing strength of the D− − singlet transition. The D01s–2p+transition increases in strength at the expense of the D−singlet in this field range. These results reflect directly the importance of the repulsive electron–electron interaction in this unique system, where the balance between the electron–electron repulsion and the attractive interactions of the electrons with the positively charged impurity center can be 'tuned' by magnetic field. The experimental results are in good agreement with theoretical predictions.


EORTC 30904 reported that for solitary renal mass <=5cm, radical nephrectomy (RN) is associated with higher overall survival compared with nephron sparing surgery (NSS). This trial remains the only available level one evidence on this subject. To test external validity of the trial, patients who met clinical and pathological inclusion criteria of EORTC 30904 within the National Cancer Database (NCDB) were identified. We found that median age (60years in NCDB vs. 62years in trial) and median clinical tumour size (30mm in both) were similar between the cohorts. These two variables are most important determinants of mortality and stage of cancer, respectively, implying that the trial was able to recruit patients virtually representative of those seen in "real-world" practice. Moreover, in NCDB, more patients had clear-cell histology (81.9% vs. 62.9% in trial) and high-grade disease (21.1% vs. 11.2% in trial), implying more aggressive tumors compared to the trial. Arguably, these patients are better served with RN which has a higher probability of completely eradicating the tumor, making the results of the trial even more relevant to practice. Our results indicate that EORTC 30904 cohort was not significantly different from the NCDB cohort in a manner that could influence reported trial outcomes.

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Vibro-acoustic analysis methods and related software for noise analysis of offshore platforms,FPSO structures,etc.were summarized and discussed.It was elaborated that there are two paths in transmission-airborne transmission and structural borne transmission,and both of them should be considered in the analysis.Moreover,it was indicated that the fast multi-pole boundary element method would play an important role in vibro-acoustic analysis in the future.


This article explores the new friendship treaty between Russia and the DPRK focusing on Russia's shifting relations with the two Koreas, the process leading to the signing of the new treaty, and the treaty's implications for peace and security in Northeast Asia. Russia seeks a balanced relationship (or even-handed approach) with the two Koreas, while separating politics and economics. By doing so, Moscow will try to enhance its influence and prestige in Korean affairs.


The Identity principle says that conditionals with the form 'If p, then p' are logical truths. Identity is overwhelmingly plausible, and has rarely been explicitly challenged. But a wide range of conditionals nonetheless invalidate it. I explain the problem, and argue that the culprit is the principle known as Import-Export, which we must thus reject. I then explore how we can reject Import-Export in a way that still makes sense of the intuitions that support it, arguing that the differences between indicative and subjunctive conditionals play a key role in solving this puzzle.


The dynamic avalanche reliability of 1200-V silicon carbide (SiC) power metal-oxide semiconductor field-effect transistors (MOSFETs) is studied in this article. The unclamped inductive switching (UIS) tests are conducted to locate failure points. An optimized thermal network model with the definition of the material above the epitaxial layer is used to simulate the avalanche process of SiC MOSFETs. The simulation and experiment results are matched, which verifies the validity of this model. Further simulation results show that a slight change in the doping profile of the p-well region will make the avalanche capability significantly different. Then, the effect of the deviation in cell parameters on the avalanche capability is studied by multicell simulation. The results demonstrate that uneven distribution of internal parameters makes the parasitic bipolar junction transistor (BJT) of some cells turn-on first, causing a significant concentration of current and heat in a very short time, and eventually forming hot spots often observed in failed devices.


The electro-oxidation of ammonia has attracted much attention in recent years since it addresses both the clean energy supply free of COx and environmental protection. However, the large-scale applications of ammonia electro-oxidation technologies have been strongly hindered by the insufficient performance and the high cost of the electrocatalysts related to the usage of high Pt loadings. Therefore, considerable effort has been devoted to developing electrocatalysts for ammonia electro-oxidation with improved activity and lower Pt loading over the past 10 years. From the initial focus on pure metal electrocatalysts, a wide range of Pt-based and Pt-free electrocatalysts for ammonia electro-oxidation have been investigated. This review begins with a brief discussion on the mechanism of the ammonia electro-oxidation with particular attention on the latest findings on the active intermediates and poisoning species, which is important for the fundamental understanding of the principles of improving the electrocatalyst performance for ammonia electro-oxidation. Typical types of electrocatalysts for ammonia electro-oxidation are next described, including pure metal, Pt alloy and Pt-free electrocatalysts. The various preparation methods are discussed and related to the resulting structures and electrocatalytic properties for ammonia electro-oxidation. The factors influencing the performance of the electrocatalysts are also highlighted for gaining fundamental insight into the optimization of the electrocatalyst performance. Based on the results achieved in this area, several future research directions are finally proposed and discussed.


A simple method of determining the critical diameter of cast and extruded charges is described; it consists of following the ionized detonation front, propagated from the base of a right circular cone, by means of an internal continuous wire sensor. The critical diameter is tha t cone diameter at which detonation fails, i.e., ionization disappears. The method developed is found to be particularly appropriate for organic materials of moderate to low shock sensitivity. Measurements obtained during the development work ranged from 0.61 cm for octol 65/35 to 2.69 cm for creamed cast TNT; the individual record readings could be repeated to =h 0.03 cm and =b 0.2 cm, respectively, in critical diameter.


The objective of this work is to evaluate microbiological parameters of milk and veal marketed in the city of Tucurui, in the state of Para. To this, were made analysis of total coliform, coliform organisms, Salmonella sp. and Staphylococcus spp. of 14 samples (seven pasteurized and seven in natura). The methods used for the microbiological analysis were according to Resolution RDC no 12, of January 2, 2001 of the National Agency of Sanitary Surveillance, in line with the parameters proposed by the American Public Health Association. For total coliforms, the pasteurized milk presented six samples with values of <0,3 NMP/mL and only one with value 20 NMP/mL; already the milk in natura presented values that varied between 43 NMP/ mL to 1100 NMP/mL. For coliform organisms, all of the samples of milk pasteurized were with the value <0,3 NM/mL; for samples of milk in natura, the values were between <0,3 NMP/mL and 1100 NMP/mL. For Salmonella , of the 14 samples analyzed, only one of milk in natura showed positive result for this parameter. For Staphylococcus spp., only three samples of pasteurized milk were positive, with results of 2x10 UFC/mL to 8x10 UFC/mL; for the milk in natura, all of the samples were positive, with results between 2,5x10 2 UFC/mL to 8,8x10 4 . With this, the results indicate that there is still need for improvement in the standardization of this raw material and in the techniques even more effective handling of milk in the municipality of Tucurui, Para. Keywords : Hygiene; Standardization; Beef.


. This study aimed to investigate the effects of rapid population growth and urbanization on forests, in-forest recreation areas and urban forests in Turkey. Therefore, through the consideration of the urban population changes in Turkey between 1973-2019, "Forestry Statistics" related to the changes in the forest existence, in-forest recreational areas and urban forests were evaluated. Within the scope of "Forestry Statistics", both forestry data and population data were considered separate variables, and 36 variables were created in this context. According to this, while the total forest area in Turkey was 20,199,296 ha in 1973, it increased by 2,541,001 ha (12.6%) and reached 22,740,297 ha by 2019. According to the up-to-date data, there have been increases in growing stock and annual current increment, as well as forest areas in Turkey. It is a fact that there is a transformation in favor of forests in rural areas of the country. However, it is not possible to talk about a similar situation in urban areas. Although there is a positive correlation between the urban population and forest presence across the country, it is not at the same rate. The urban population increases several times faster than the extent of forest areas and growing stock.


Background. According to literature data, errors in the diagnosis of gastrointestinal tumors (GIST) are uncommon, accounting for approximately 6% of cases that results in treatment failure. Case report. Here, we describe a rare case of a 58-year-old female patient with extragastrointestinal stromal tumor (EGIST) in the evidence of testicular feminisation syndrome (TFS) – Morris syndrome. This hereditary pathology is associated with complete insensitivity of target organs to androgens and was described in 1953 by the American gynaecologist John Morris. The patient was referred to the cancer clinic, where she was wrongly diagnosed with uterine leiomyoma. Interdisciplinary approach, cancer alarm, active surgical tactics, additional immunohistochemical (IHC) and molecular genetic studies (MGI) allowed verifcation of the true diagnosis. There are reported cases of EGIST of the bladder, prostate, retroperitoneum, mesentery, omentum, and posterior mediastinum. However, we were not able to fnd publications regarding the cases of EGIST originating from the vaginal wall. Combination of TFS and EGIST is a unique case in our clinical practice. Conclusion. The study of rare cases expands the understanding of the molecular pathogenesis of malignancies. Patients with rare types of malignant tumors should be obligatorily examined and treated in specialized cancer clinics with involvement of certifed oncologists, surgeons, chemotherapists, geneticists.


INDIAN PEDIATRICS 372 VOLUME 43__APRIL 17, 2006 We think that more needs to be done to avoid such situations in the future. To discourage authors from not responding to a pertinent query the authors should be informed that the query has been considered as pertinent and that it would be published, even if they choose not to respond. To decide whether the query is pertinent the journal can have an expert committee or seek the help of the reviewers of the article. Also, the journal website should be constructed in such a manner that the query once published is linked to the article and the fact regarding authors' non-response should be mentioned at the end of the article itself. This would alert the readers who read the article from the website and they would be then able to draw their own conclusions about the quality of the article. The editors should also consider if it is possible to publish authors' reply requiring detailed response under a new title so that it could be listed on PubMed as a separate publication. Sandeep B. Bavdekar, Sunil Karande, Seth Gordhandas Sunderdas Medical College and KEM Hospital, Parel Mumbai and Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai, India. E-mail: email@example.com.


We investigate the concern that compliant interconnects due to their generally long, thin shape will introduce extra insertion loss for high-frequency signals, due to the added inductance at the die-package interface. We show that, as expected, an increase of the inductance in an inductive and resistive transition always causes additional insertion loss. However, in a complete system on-die drivers and receivers are connected to the die-package interface. Considering a capacitive and inductive-resistive transition, we show that for a given total pad capacitance there exists an optimal inductance that leads to a minimization of the insertion loss at the die-package interface. We refer to this as the pad capacitance compensation effect. As a significant finding, it appears that compliant interconnects can add some but not too much inductance at the die-package interface, so that the high-speed performance is actually improved. As an electromagnetically sound proof of the pad capacitance compensation concept, we perform full-wave simulations of variations of a generic die-package interface. Helical spring structures with different pitches and standard bumps are compared. Based on an appropriate post-processing of the simulation results the pad capacitance compensation effect for compliant interconnects is confirmed. As a final step, equivalent lumped-element representations (with frequency-dependent parameters) are derived directly from the simulated S parameters and a comparison with a 3-D quasistatic computation is made. This shows that the improved insertion loss for compliant interconnects is indeed correlated with an increased inductance of the structures.


In changing context of the present-day world, trade openness has a crucial role to play in economic development of different countries. Besides other factors, institutional quality plays a vibrant role in achieving a high growth rate. The objective of the present study is to understand how institutional quality influences economic growth and trade openness in India. To achieve the objectives of the study, Autoregressive Distributed Lag bound testing approach has been used. The findings show that there exists long-run relationship between the variables used in this study. From the findings, it can be concluded that total trade has a negative impact, whereas export enhances economic growth in the country. The results also show that improvement in institutional quality has a positive impact on economic growth. Thus the findings suggest that the country needs to adopt policies that can improve the quality of institutions and can enhance the formation of physical and human capital.


Objective To observe the curative effect of vinpocetine and Shu-Xue-Nin injection in treating vertebro-basilar artery insufficiency.Methods 144 cases with vertebro-basilar artery insufficiency were selected and divided into 4 groups randomly.Cases in the control group were given conventional therapy;Cases in the vinpocetine group were given intravenous drip infusion of 20mg vinpocetine combined with 250mL physiological saline,once daily.Cases in the Shu-Xue-Nin group were given intravenous drip infusion of 20mL Shu-Xue-Nin injection combined with 250mL physiological saline,once daily.Cases in the therapeutic alliance group were given intravenous drip infusion of vinpocetine and Shu-Xue-Nin injection once daily for 2 weeks.Results(1)The total effective rate of therapeutic alliance group(94.4%),vinpocetine group(77.8%)and shu xue-nin group(75.0%)were higher than those in control group(63.9%)(P0.01).The total effective rate of therapeutic alliance group were higher than those in vinpocetine group and in Shu-Xue-Nin group(P0.05).(2)After the treatment,blood flow relocity of vertebrobasilar and hemorheology index of 4 groups improved more than those before the treatment(P0.05).(3)After the treatment,blood flow relocity of vertebrobasilar and hemorheology index in therapeutic alliance group showed higher improvement than those in vinpocetine group and in Shu-Xue-Nin group(P0.05).Conclusion Vinpocetine or Shu-Xue-Nin injection has a satisfactory effect on vertebro-basilar artery insufficiency.Combination treatment shows better effect than single one.


Objective:To investigate patients with schizophrenia before and after treatment of serum thyroid hormones(T3,T4,TSH,FT3 and FT4) levels in the dynamic changes of the clinical relationship.Methods:Chemiluminescence immunoassay detected in 60 patients with schizophrenia before and after treatment of serum triiodothyronine 3(T3),thyroxine(T4),free triiodothyronine 3(FT3),free thyroxine(FT4) and thyroid stimulating hormone(TSH) level and with 50 normal healthy people for comparison.Results: of serum thyroid hormone levels in patients with schizophrenia before treatment compared with the control group,the difference was not statistically significant(P 0.05);After treatment,serum T3,T4 levels to decline,and the most significant decline in T4,and TSH levels increased significantly compared with before treatment,compared with the control group,there were significant differences(P 0.05);thyroid hormone in patients with schizophrenia level after treatment to sex showed no statistical significance(P 0.05).Conclusions: Antipsychotic drugs can cause schizophrenia patients with thyroid hormone levels change,so the clinical course of treatment of thyroid hormone levels should be monitored regularly in order to develop better measures for rehabilitation treatment of patients with schizophrenia.


In an analitic study of the Parasitology and microbiology and the Peruvian Parasitology congresses and many national publications about, of the last 25 years, it has been abstracted prevalence ciphers of the parasitic diseases in the human intestinal-hepatic segment, that had been taken using the microscopic-fecal test. Using this test, we could obtain 31306 samples, principally of students from: the urban, suburb and rural areas, in almost all over the country. It could be found the following average ciphers: 27.4% (with limits between 0.5-95.0) for nematodes (Ascaris, Trichuris, Uncinarias: Necator orancylostoina, Strongyloides, Enterobius); 6.1% (with limits between 0.2-50.0) for cestodes (Taenia, Hymenolepis, Diphyllobothrium); 6.8% (with limits between 0.3-17.9) for Fasciola; and 17.4% (with limits between 0.3-58.1) forprotozoa (Entamoeba, Giardia, Endolimax, Balantidium, Chilomastix, Iodamoeba, Blastocystis, Cryptosporidium, Cyclospora). With this registered information, we conclude to propose the necesity of improve prevention and control programs for this parasites.


The disentanglement of StyleGAN latent space has paved the way for realistic and controllable image editing, but does StyleGAN know anything about temporal motion, as it was only trained on static images? To study the motion features in the latent space of StyleGAN, in this paper, we hypothesize and demonstrate that a series of meaningful, natural, and versatile small, local movements (referred to as"micromotion", such as expression, head movement, and aging effect) can be represented in low-rank spaces extracted from the latent space of a conventionally pre-trained StyleGAN-v2 model for face generation, with the guidance of proper"anchors"in the form of either short text or video clips. Starting from one target face image, with the editing direction decoded from the low-rank space, its micromotion features can be represented as simple as an affine transformation over its latent feature. Perhaps more surprisingly, such micromotion subspace, even learned from just single target face, can be painlessly transferred to other unseen face images, even those from vastly different domains (such as oil painting, cartoon, and sculpture faces). It demonstrates that the local feature geometry corresponding to one type of micromotion is aligned across different face subjects, and hence that StyleGAN-v2 is indeed"secretly"aware of the subject-disentangled feature variations caused by that micromotion. We present various successful examples of applying our low-dimensional micromotion subspace technique to directly and effortlessly manipulate faces, showing high robustness, low computational overhead, and impressive domain transferability. Our codes are available at https://github.com/wuqiuche/micromotion-StyleGAN.


The behaviour of international NGOs (INGOs) continues to impede aid effectiveness. The reasons for this are identified. Six prescriptions are offered which, if adopted by INGOs, would reduce the harm that they cause.


Unbalanced electromagnetron operated in Ar/n-hexane mixture was employed for deposition of composite Ag/C:H films. For comparison composite Ni/C:H films were prepared in a similar way using unbalanced planar magnetron with permanent magnets. Optical transmission measurements, TEM micrographs, and dc electrical measurements, were used to study ageing effects of the composites in the ambient atmosphere.


A landmark development in the fight against drug trafficking and other types of fraud in Nigeria was the promulgation of the Money Laundering Decree No. 3 of 1995. Though this is an integral part of an international effort which started mainly to curtail drug trafficking, its adoption in Nigeria is particularly notable given the reputation of the country for fraud, corruption and drug trafficking. For instance, a recent survey by Transparency International — a German‐based international group that interviewed business people worldwide — listed Nigeria as the most corrupt country in the world. Also the infamous Nigerian advance fee fraud scam ('419'), codenamed after the section of the criminal code that deals with such fraud, is currently a subject of international attention while the country is also widely criticised as a centre for drug trafficking. It has, for instance, been noted that:


173 women were followed up for 3-4 years to study the efficiency reversibility and long-term side effects of daily administration of 600 mcg of norethisterone acetate as a contraceptive agent. Continuation rate was 38.7/100 after 16-43 months of use. Reasons for interrupting the treatment were in 25.4% of cases the incidence of menstrual disorders such as amenorrhea; cycles too short or too long; breakthrough bleeding; oligomenorrhea; and menorrhagia. There were 4 pregnancies comparable to an effectivenss rate of 0.7/100 on the Pearl index; reversibility did not present any problem. Side effects on breast cervical mucus and vaginal epithelium were minimal while the uterine mucosa showed signs of hypoplasia. Blood pressure and body weight did not change sensibly. Contraception by mini pill seems to be indicated for women who cannot tolerate estrogen and administration of norethisterone acetate seems to yield better results than norethisterone only.


Due to the rapid development of perinatal care in the Russian Federation, there has been an increase in the survival rate of premature infants with very low and extremely low birth weight in recent decades. This patient cohort is characterized by the development of several severe disabling conditions that cause health problems in older age. The structure of morbidity of children born preterm has its own features – almost 100% of these patients have pathology of the nervous system, they are susceptible to diseases of the respiratory system, and diseases of the sensory system are more common. The care and rehabilitation of these patients requires high financial costs. This article presents a review of literary data concerning the results of studies that assessed the need for medical care, the structure of morbidity of premature children at different ages, depending on the birth weight and gestational age. Key words: morbidity, medical care, preemies, review, very low birth weight, extremely low birth weight


In January 1999 a change management Project named "Organizational change and development in the Municipality of Rome – Local Taxes Office" began. The main objective was to simultaneously improve: (a) the effectiveness of the information system; (b) the organizational climate; (c) the quality of service provided to citizens; (d) the effectiveness of personnel communications. The Project was based on participatory ergonomics principles aimed at empowering people at any level of the organization. The Project is still in progress. In this paper some methodological aspects and preliminary results are presented and discussed.


The utility model provides a curing equipment is glued to integration point. Equipment includes position adjustment mechanism, balance mechanism, and the point gum machine constructs and constructs the UV photocuring mechanism that sets up side by side with the point gum machine, still includes control mechanism. Balance mechanism removes to through Y axle module and sets for the position after putting the lens cone that needs the good clamping ring of installation that the point glued in advance well, and the point gum machine constructs and removes balance mechanism top through X axle module, moves down to the point that corresponds by Z axle module again and glues the position and accomplish and a little glue, and the point is glued the back control mechanism control point that finishes and is glued the mechanism and move to left, and then UV photocuring mechanism removes balance mechanism top counter point and glues the position and carry out the solidification of UV light struck. The point is glued curing equipment and is adopted the gluey and glue solidification process of the point that can accomplish lens cone and clamping ring post assembling simultaneously, and the automation degree is high, practices thrift manpower and materials, and can improve the product quality of post assembling greatly.


Supplemental Digital Content is Available in the Text. Background: There is a need to characterize patients with HIV with suspected severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Setting: Multicenter registry of patients from 116 emergency departments in 27 US states. Methods: Planned secondary analysis of patients with suspected SARS-CoV-2, with (n = 415) and without (n = 25,306) HIV. Descriptive statistics were used to compare patient information and clinical characteristics by SARS-CoV-2 and HIV status. Unadjusted and multivariable models were used to explore factors associated with death, intubation, and hospital length of stay. Kaplan–Meier curves were used to estimate survival by SARS-CoV-2 and HIV infection status. Results: Patients with both SARS-CoV-2 and HIV and patients with SARS-CoV-2 but without HIV had similar admission rates (62.7% versus 58.6%, P = 0.24), hospitalization characteristics [eg, rates of admission to the intensive care unit from the emergency department (5.0% versus 6.3%, P = 0.45) and intubation (10% versus 13.3%, P = 0.17)], and rates of death (13.9% versus 15.1%, P = 0.65). They also had a similar cumulative risk of death (log-rank P = 0.72). However, patients with both HIV and SARS-CoV-2 infections compared with patients with HIV but without SAR-CoV-2 had worsened outcomes, including increased mortality (13.9% versus 5.1%, P < 0.01, log-rank P < 0.0001) and their deaths occurred sooner (median 11.5 versus 34 days, P < 0.01). Conclusions: Among emergency department patients with HIV, clinical outcomes associated with SARS-CoV-2 infection are not worse when compared with patients without HIV, but SARS-CoV-2 infection increased the risk of death in patients with HIV.


C RITICAL probing of the traditional proofs for the existence of God has marked English Christian philosophical speculation within the past few years.' The classical 'five ways' of St Thomas have not been abandoned as counterfeit metaphysical coin, but their cogency for the intellectual of to-day has been called into question. More and more it is recognized that it does little good to tell a man that the arguments do demonstrate the existence of God, when this man sees nothing but a rather elementary exercise in logic. The proofs leave the contemporary intellectual aloof and uninterested: he is not impressed. Why? It is doubtful whether that question can be answered by a philosopher who acts specifically as a metaphysician. His specific role is fulfilled when he has demonstrated. If his demonstration fails to elicit assent, and it does so fail to-day, he must leave what Jacques Maritain has called his 'heaven of intelligible necessities'; he must go down into the intellectual marketplace and listen to the voice of modern man; the theist must discover, with the help of every human thing, why the truth is not seen, even when revealed to the cultivated intellect of the day. Unless he does this, the Christian philosopher will find himself preaching to the converted in the upper chambers reserved for the Faithful. His duty, not only to the Gentiles but to himself, forbids the luxury of intellectual inbreeding. The common good demands of him a judgement on this crucial issue, and his refusal to judge may result in the simple loss of his right to practise the profession of Wisdom. If the Western civilized mind cannot grasp the existence of God as the demonstrated conclusion of a process of metaphysical reasoning, may it not be because that mind is incapable of


It is pointed out that the most recent volcanism and much of the oldest tectonic activity on Mars have apparently occurred within the Tharsis region. Detailed geologic mapping from Viking images has provided new information on the evolutionary history of the region. The eruptive sequence and areal extent of lava flows in the Tharsis region have been defined by stratigraphic studies and crater counts made on individual flow units. Faults and fractures transecting these units provide a record of changing tectonic intensity during the period of high volcanic activity. Volcanism began with the resurfacing of basement rocks early in the history of the region and continued without large interruptions through nine major eruptive episodes. Volcanic centers shifted from place to place but resurgent activity occurred at several volcanoes. Volcanism culminated during the foration of large shield volcanoes along Tharsis Montes and thereafter appears to have gradually declined.


We appreciate the opportunity to resubmit our article "Indications for different types of brittle failure due to active coal mining using waveform similarities of induced seismis events". The whole paper has been revised and all comments by the Referees have been addressed, with corresponding changes made directly to the manuscript where appropriate. Accompanying this letter, please find a revised version of our manuscript. Detailed responses to the Referees' comments are included below.


In 1867, Federico Delpino, with his seminal work "Pensieri sulla biologia vegetale" (Thoughts on plant biology) established plant biology by defining it not in the broad general sense, namely as the science of living beings, but as a branch of natural science dedicated to the study of plant life in relation to the environment. Today, the figure and achievements of this outstanding plant scientist it is almost unknown. In the following pages, I will concisely describe the main realizations of Federico Delpino and outline the significance of his work for modern plant science.


Objective To investigate the effect of sodium hydroxybutyrate(GHB) on expression of hippocampal N-methyl-D-aspartate receptor 1 subunit (NR1) mRNA in the neonatal rat with hypoxic-ischemic insult. Methods One hundred eighty seven-day(7d) old Sprague Dawley rat pups of either sex weighting 10 g~14 g were randomly assigned to sham group(S), normal saline group(C),GHB 50 mg/kg group(γ50),GHB 100 mg/kg group(γ100)and GHB 200 mg/kg group(γ200),n=6.The procedure for the induction of hypoxia-ischemia was done according to the way described by Rice:under ether anesthesia,pups were subjected to left carotid artery ligated followed by 2 h of hypoxic exposure(O2:N2=8﹪:92﹪).The pups in S group were only aparted left carotid artery which was not obturated and no hypoxia.GHB 50 mg/kg, 100 mg/kg, 200 mg/kg was administered i.p immediately after hypoxia,then a time every 8h inγ50、γ100 and γ200 group respectively.The same volume normal saline was administered i.p in the same way in S and C group.Reverse transcriptase polymerase chain reaction(RT-PCR) was used to analyze the expression of NR1 mRNA semi-quantificationally in the left hippocampus at 2 h、6 h、12 h、1 d、3 d、7 d after insult in S、C、γ50、γ100 and γ200 group. Results The difference of expression of NR1 mRNA between S and C group wasn't significant.At any time after insult, The differences of expression of NR1 mRNA among C and three GHB group were not significant too. Conclusion Hypoxia-ischemia and GHB didn't significantly affect the expression of NR1 mRNA in neonatal rat hippocampus.


This work has as main objective to analyze the dynamics of prioritization and distribution of value for stakeholders in the shared economy model and the capacity to serve them in a sustainable way in the long term. To that end, 22 qualitative interviews were conducted, representing specialists, managers, professionals, shareholders and clients, both stakeholders involved in the shared economy. The vision of the results obtained is that the business model is necessary for the economic and social scenario predicted for the coming years and its applicability is feasible in the medium and long term although it is still necessary to prove financially sustainable. The fact that it is a recent model, with little information and studies that underlies the theme, makes the contribution of this study relevant both in the theoretical and practical view, besides using an innovative approach, by showing a new perspective on the shared economy through of different stakeholders.


Objective To investigate the roles of hemopoietic stem cells (HSCs) in the pathogenesis of psoriasis. Methods HSCs were isolated from the bone marrow of a patient with psoriasis vulgaris and a normal human control. Forward- and reverse-subtracted cDNA libraries were constructed by using suppression subtractive hybridization (SSH) technique between HSCs from the patient and control. Bacterial PCR and dot hybridization were performed to screen for positive clones followed by gene sequencing, identification and functional analysis. Real time quantitative PCR was carried out to measure the mRNA expression of interferon-γ and thymosin 10 (TMSB10). Results Nine genes were screened from the forward-subtracted cDNA library which encoded interferon-γ, tyrosine phosphatase, SUMO1 activase, etc, and 8 genes including the TMSB10-encoding gene were screened from the reverse-subtracted cDNA library. The relative expression level of interferon-γ in HSCs from the patient was 47.5 times that in HSCs from the control, while the level of TMSB10 from the control was 22.6 times that from the patient. Conclusion The abnormal expression of 17 genes which encode interferon-γ, thyrosin, and so on, may be involved in the development of psoriasis.

Key words:
Psoriasis;  Bone marrow;  Hematopoietic stem cells;  Gene expression


Formation of 3,5-disubstituted 1,2,4-thiadiazoles by the reaction of sulfur dichloride with nitriles in the presence of a Lewis acid was found. For example, 3,5-diphenyl-1,2,4-thiadiazole was obtained with its chlorinated products, 3-o-chlorophenyl-5-phenyl- and 3-p-chlorophenyl-5-phenyl-1,2,4-thiadiazoles, from benzonitrile and sulfur dichloride using aluminium chloride as a catalyst (total yield 80%). The extent of chlorination of the aromatic ring was suppressed by use of iron(III) chloride as the catalyst or of sulfur chloride instead of the dichloride. Some substituted benzonitriles and pivalonitrile also gave thiadiazoles in lower yields.


Abstract : The paper discusses the origin, distribution and magnitude of photographic recording noise in thin amplitude holograms. Three types of noise are distinguished. The first is intermodulation noise which arises due to the non-linearity of the amplitude transmittance-exposure characteristics of the photographic emulsion. Its magnitude can be predicted using a recently reported theory, applicable to diffusely illuminated objects. The second type of noise is surface-relief noise which arises from the distortions of the emulsion surface as a consequence of chemical processing. The final type of noise is film-grain noise which arises from the granular nature of the photosensitive material. Calculations show that for the small object used in these studies, the noise introduced by the film grains is less than that due to intermodulation noise. (Author)


An independent review of 632 student evaluation summaries detected 243 items of concern across all assessed educational dimensions. Students were found to provoke significantly more concerns in the first unit than in any other preclerkship unit. Almost twice as many concerns were raised in the clerkship, which occupies only one third of the program, as in the preclerkship. Most of these occurred in the Psychiatry, Family Medicine, and Internal Medicine rotations. Throughout the entire program, the main areas of concern were in problem solving and clinical skills, with knowledge joining these only in the clerkship. A cluster analysis revealed an independence of the six dimensions on which the students are evaluated. Some generalizable findings arising from this study include the following: (a) Students require time to adjust to medical school, particularly to a problem‐based curriculum; (b) simultaneous, interlocking clerkships may be especially problematic to some students; (c) shorter clerkship rotations...


Achievements have been made in educational narrative researches over the past decade in relation to features,values,existing problems and upgrading strategies.However,more extensive visions need strengthening in the future researches to break through the limits of abuses of the scientificism,closedness of structures,and deficiency of ontology.


In this paper, we address the two-machine flowshop with sequence-independent setup times. Heuristic algorithms are proposed to find a near-optimal solution. We propose a constructive heuristic based on new priority rule, local search procedures and a genetic local search algorithm for the problem under consideration. Computational results show that local search procedures contribute to have a better results.


Central to the whole body of argument of the economic theory of public choice is that political parties use policies to acquire votes.' The evidence for i t is extensive.2 I t has been ingeniously used to explain a variety of phenomena. For instance, Fiorina has argued that it is as a consequence of politicians having learnt to use their influence over service provision for electoral advantage that a decreasing proportion of seats in the American Congress are marginal.3 The central insight has been used to explain the expenditure of subordinate governments. Examples are Borcherding and D e a ~ o n , ~ Ohls and


Objective To evaluate orbital CT examination in the clinical application.Methods This was a retrospective case series.The data of 457 cases of orbital CT examination treated by us in the past five and a half years were reviewed and analyzed.Results CT examination of 95 cases were found normal,362 cases were found abnormalities,including the orbital and intraocular foreign body,orbital bone fracture,orbital soft tissue injury,lens dislocation,lens extrusion,deformation,compound eye damage,the orbital and intraocular tumor,exophthalmos and inflammatory pseudotumor.Conclusions CT is used widely in ocular trauma,the orbital and intraocular tumor etc.It's proved that CT is the preferred methods of examination for clinical diagnosis and surgical.

Key words:
Ocular trauma;  Computed tomography;  Retrospective analysis


FIELD: metallurgy. SUBSTANCE: proposed composition contains the following substances, in wt. %: Powder of additional alloy with rear-earth metal of cerium group 30-40, granulated calcium 12-15, granulated barium 8-10, fluorite and/or cryolite 5-10, aluminium powder 20-25, iron powder making the rest. EFFECT: higher cold resistance of cast articles of low alloy steels, higher mechanical properties. 2 tbl


In order to transmit signals with better quality in severe noise powerline channel,a new modulation method SOQPSK-MIL(Shaped-offset quadrature phase-shift keying-Military)is proposed here.Compared with the method proposed by Simon which has 16 different waveforms,the new scheme has only half number waveforms.The number is reduced to half for the demodulation of the received signal through the less filter number.This shows that the modulation method is good for powerline channel with the merit of no performance degradation.The demodulation method is given here for the received signal.Compared with the noisy powerline communication environment,this method is fit for severe noisy channel.


Teleost fishes display a remarkable diversity of adult dentitions; this diversity is all the more remarkable in light of the uniformity of first-generation dentitions. Few studies have quantitatively documented the transition between generalized first-generation dentitions and specialized adult dentitions in teleosts. We investigated this transition in the Mexican tetra, Astyanax mexicanus (Characidae), by measuring aspects of the dentition in an ontogenetic series of individuals from embryos to 160 days old, in addition to adults of unknown age. The first-generation dentition and its immediate successors consist of small, unicuspid teeth that develop extraosseously. Multicuspid teeth first appear during the second tooth replacement event, and are derived from single tooth germs, rather than from the fusion of multiple conical tooth germs. We document that the transition from unicuspid to multicuspid teeth corresponds to a change in the location of developing tooth germs (from extraosseous to intraosseous) and in patterns of tooth replacement (from haphazard to simultaneous within a jaw quadrant). In addition, while the size of the largest teeth scales with positive allometry to fish size, the transition to multicuspid teeth is accompanied by an exceptionally large increase in tooth size. (c) 2005 The Linnean Society of London, Zoological Journal of the Linnean Society, 2005, 145, 523-538.


1 Among older people (65 years of age and older), many worry about their health, family, financial situation and mortality. These worries are even more likely to arise when they feel that their physical and mental capacities are diminishing and that they are loosing their autonomy. This is considered as normal anxiety. However, sometimes anxiety is so intense that it causes significant impairment in the person's daily functioning and becomes an important source of distress. This kind of anxiety is not normal and it is called an anxiety disorder.


Assessment of scientific attitude in science study,important is executed along of in study of science relates to abiliti, causing becomes solvent student referance or inabiliti at study. Attitude contains three dimensions namely cognate trust, feeling of akfektif or evaluatif and behavior of someone to attitude object. Assessment result of learning Sains is assumed complete if including cognate aspect, affective, and psikomotor. Attitude is bahaviour having the character of public disseminating is thin is of all thing done by student. But attitude also is one other having an in with result of student learning. Distinguishable scientific attitude from simply attitude to Sains, because attitude to Sains only be focused at does student like or doesn\'t like to study Sains. Of course positive attitude to study of Sains will give high contribution in forming of scientific attitude of student.


The absence of a sustained analysis of the category of art cinema is sometimes seen as a curious gap in an otherwise rich and expanding body of scholarship on Indian films. Ravi Vasudevan drew attention to this gap in his observation that in recent years, "the ground of public and film-critical attention has shifted, and four areas of Indian cinema have become visible": popular formats, diaspora productions, international collaborations, and documentary films. "The Indian art film and author cinema," he added, "continues to be showcased at home and abroad, but has become somewhat marginal both to public discussion and scholarly engagement." Seldom analyzed, the category of art cinema circulates, however, in writings of commentators in the mainstream media, film critics, state officials, and film studies specialists, who write as if it refers to a definite and distinct set of objects called art films. In such usage, art


All of the tools used to create the world of Germinal are unearthed and discovered in real time in front of the audience. The performance's structure follows the discoveries of stage layers and objects, all of which are considered, then used or rejected in this construction of something from nothing. In my September 19, 2014 interview with Goerger and Defoort at the Portland Institute for Contemporary Art, Defoort explained that Germinal came about after working on — and ultimately rejecting — an idea for a different performance:


The reaction follows the pattern established for the triplet state reactions of olefins in general. The major products, ethylene, 1,3-butadiene, vinylcyclobutane, cyclohexane, various C12-compounds, and polymer, can best be accounted for by the allylic C—H and C—C bond cleavage of the primary triplet biradicals and the ring closure and fragmentation reactions of the resulting open chain biradicals. At least three types of triplet state species must be involved in the mechanism. The rate equations, developed on the assumed mechanism, satisfactorily describe the observed product distribution and kinetic features of the system and permit the estimation of the elementary rate constant values and the lifetimes of the various transient biradicals involved. Preliminary experiments with cycloheptene indicate that vinylcyclopentane is an important product.


Background: Varicella-zoster infection is a serious and potentially fatal disease, especially among newborns.Several studies have described postnatal varicella zoster exposure among neonates and reported on the efficacy of varicella-zoster immunoglobulins (VZIG) used as post-exposure prophylaxis. Unfortunately, VZIG is not available in Jordan. A limited number of studies have investigated the efficacy of intravenous immunoglobulins (IVIG) as an alternative preventive post-exposure to the varicella virus. Methods: This retrospective descriptive study was conducted to review the outcomes of two separate incidents of varicella-zoster exposure and the prophylactic use of IVIG in the neonatal intensive care unit in Jordan. Results: The sources of exposure in both incidents infected medical health workers. During the exposure, cohort measures were applied to neonates whose mothers did not receive immune prophylaxis against IVIG. Newborns were followed appropriately. Totally, 22 cases were identified representing two exposure incidents without a varicella-zoster infection. Conclusion: The results indicated that IVIG was an effective prophylactic therapy for neonates post varicella virus exposure.


The Coatings Editorial Board and Editorial Team would like to congratulate the winner of the Coatings 2023 Best Paper Award (Review) [...]


In the teaching on electronics technology,implementation of quality education needs to change the education notion,and turn "teaching" to "guiding",which makes the students autonomously study,harmoniously study and finally to create a harmonious relationship between teacher and student,and to know the value of life.


Summary The recent continuously emerging rampancy of novel coronavirus (SARS-CoV-2) that started in Wuhan in late December 2019 has become an international public health emergency and is still spreading rapidly in the world. Up to October 11, 2020, 37.109.6851 confirmed cases of COVID-19 have been announced with 2.8 percent death, which means 1.070.355 confirmed death cases. At the moment, a specific vaccine or drug for the new coronavirus is not available; thus, the development of a drug with far-reaching HCoV inhibitory activity is an urgent medical need. It is, however, vital to first comprehend the nature of this family and other coronaviruses that have caused the outbreak. Here, we relate the epidemiological and virological characteristics of the COVID-19, SARS, and MERS rampancy.


LBA5506 Background: Olaparib (ola) maintenance (mtx) improved outcomes in pts with newly diagnosed AOC and a BRCAm (DiSilvestro J Clin Oncol 2023;41:609–17) or with bev in pts with homologous recombination deficiency (HRD+) tumors (Ray-Coquard Ann Oncol 2022: LBA29) in response to 1L treatment, but an unmet need remains. Combining an immune checkpoint inhibitor with an antiangiogenic agent and a PARP inhibitor may enhance antitumor effect (Banerjee Ann Oncol 2022: 529MO). The Phase III DUO-O trial (NCT03737643) evaluates PC + bev + durva, followed by mtx bev + durva + ola, in pts with non-tBRCAm AOC in the 1L setting. Methods: Pts had newly diagnosed FIGO stage III or IV, high-grade epithelial, non-tBRCAm AOC and had completed upfront, or were planned to receive interval, debulking surgery and 1 cycle of PC ± bev. At Cycle 2, pts were randomized 1:1:1 to Arm 1: PC + bev (15 mg/kg IV q3w) + durva pbo (up to 6 cycles) followed by mtx bev (15 mg/kg IV q3w; total 15 months [mo]) + durva pbo (total 24 mo) + ola pbo (total 24 mo); Arm 2: PC + bev + durva (1120 mg IV q3w) followed by mtx bev + durva (1120 mg IV q3w) + ola pbo; or Arm 3: PC + bev + durva followed by mtx bev + durva + ola (300 mg bid tablets). The primary endpoint, progression-free survival (PFS; modified RECIST 1.1 per investigator) in Arm 3 vs Arm 1, was tested first in the non-tBRCAm HRD+ population (GIS ≥42, Myriad MyChoice CDx) and then the intent-to-treat (ITT) population. Results: 1130 pts were randomized: 378 Arm 1, 374 Arm 2, and 378 Arm 3. At a prespecified interim analysis (DCO Dec 5, 2022), a statistically significant improvement in PFS was observed for Arm 3 vs Arm 1: HR 0.49 (95% CI 0.34–0.69; P<0.0001) and HR 0.63 (95% CI 0.52–0.76; P<0.0001) in the HRD+ and ITT populations, respectively; a consistent PFS effect was observed in the HRD- subgroup (HR 0.68, 95% CI 0.54–0.86). A numerical improvement in PFS was shown for Arm 2 vs Arm 1 (ITT population), but statistical significance was not reached (Table). During the study, any serious adverse events were reported in 34%, 43% and 39% of pts in Arms 1, 2 and 3, respectively. Conclusions: PC + bev + durva followed by mtx bev + durva + ola in pts with newly diagnosed non-tBRCAm AOC resulted in a statistically significant and clinically meaningful improvement in PFS vs PC + bev followed by mtx bev. Safety was generally consistent with the known profiles of each agent. Clinical trial information: NCT03737643 . [Table: see text]


An experimental investigation has been made of the sound‐absorbing properties of liquid‐base foams and of their ability to reduce jet noise. Protein, detergent, and polymer foaming agents were used in water solutions. A method of foam generation was developed to permit systematic variation of the foam density. The investigation included measurements of sound‐absorption coefficients for both plane normal incidence waves and diffuse sound fields. The intrinsic acoustic properties of foam, e.g., the characteristic impedance and the propagation constant, were also determined. The sound emitted by a 1‐in.‐diam cold nitrogen jet was measured for subsonic (300 m/sec) and supersonic (422 m/sec) jets, with and without foam injection. Noise reductions up to 10 PNdB were measured.


The experience of different joints local invasive therapy in 68 patients with hemophilia is grounded and generalized in this article. In all of them the medicine mixture for intra-joint infections was included oxygen. In 13 patients of control group the local invasive therapy was conducted in the same regimen, but without oxygen. It was shown, that in the first group end of treatment the capacity of synovial cavity was enlarged in 3,1 times, the joint movement amplitude was increased in 24,5 degrees, the power endurance and extremities support function was improved in more shortest period.


This research project developed and evaluated practical ways of involving the public in context sensitive sound mitigation strategies. The integrated use of photo montage, PowerPoint presentation, linked traffic sound files, and audience response systems demonstrated that significant visual and aural differences could be clearly portrayed and clear preferences could be expressed by citizens and professionals alike, even where the choice menu was quite complex.


Silver Schottky contacts were fabricated on (1120) n-ZnO epilayers, which were grown on R-plane sapphire substrates by metalorganic chemical-vapor deposition. The flatband barrier height was determined to be 0.89 and 0.92 eV by current–voltage and capacitance–voltage measurements, respectively. The ideality factor was found to be 1.33.


FIELD: oil-and-gas industry. SUBSTANCE: injection wells and horizontal extracting wells are drilled, displacing agent is injected via injection wells and oil is extracted through horizontal producing wells. Producing wells are composed of branched horizontal wells drilled above water-oil surface (WOS) while vertical wells are drilled at last 50 m from branched horizontal well bottoms, completion of vertical well pool and under appropriate bottom of horizontal well. Note here that vertical well completion above appropriate bottom is effected with larger density of exposed holes than exposing under appropriate bottom to create more uniform flooding front. EFFECT: higher reservoir recovery, oil extraction rate, maximum coverage of residual oil reserves to be developed. 1 dwg


Objective: To explore the clinical value of the concentration of plasma D-dimer in patients with severe acute pancreatitis. Methods: Contents of plasma D - dimer were determined by double antibody sandwich( ELISA) and compared with other 42 cases of mild acute pancreatitis. Results: Compared with mild acute pancreatitis, the plasma D-dimer level were increased in severe pancreatitis(P 0.05). Conclusion: The change of plasma D-dimer level are closely related to the clinical development in patients with severe acute pancreatitis. Early detection of D-dimer in severe acute pancreatitis has some effect to estimate state and prognosis.


The present invention relates to a sunitinib malate preparation method, wherein particularly 2,4-dimethyl-5-aldehyde-1H-pyrrole-3-carboxylic acid is adopted as a starting raw material, carboxyl activation with carbonyl diimidazole is performed, the obtained material and N, N-diethylethylenediamine are subjected to condensation under catalysis of 1-hydroxybenzotriazole to obtain an intermediate 1, the intermediate 1 and 5-fluoro-2-oxindole react to obtain sunitinib, and the sunitinib and malic acid are directly subjected to salifying without separation so as to obtain the target product. The method of the present invention has characteristics of easy operation, high yield and high product purity, and is suitable for industrial production.


Some aspects of the transmission of Gaussian pulses in a frequency-division multiplex system have been calculated. It is assumed that each channel transmitter includes an amplifier, which may be nonlinear, with input and output filters, and that each channel receiver includes a linear amplifier with a thermal noise source at its input plus input and output filters. The influence that (a) transmitting amplifier compression, (b) maximally flat channel-dropping filters of first or second order, and (c) distribution of filtering in the system have on the signal-to-noise ratio, time crosstalk, and frequency crosstalk is calculated.


Abstract While sibling relationships are known to be important for children's social and emotional well-being, little is known about sibling relationships when both siblings are deaf or hard-of-hearing (DHH). In-depth interviews were conducted with 10 young DHH adults (20–30 years old) who had studied in mainstream schools to explore their retrospective experiences of growing up with a DHH sibling. Interviews were analyzed using interpretive phenomenological analysis. Findings revealed two superordinate themes: (1) sibling relationship and sense of self and (2) family coping and relationships, with each superordinate theme containing several subthemes. Findings highlighted the various ways sibling relationships contribute to siblings' psychological development, identity formation, and coping with deafness. Potential challenges were identifed, as well as the role of parents' attitudes and coping with hearing loss in promoting supportive sibling relationships. Parents and professionals should be aware of the valuable and unique aspects of DHH siblingship and attend to imporatnt relationship asepcts such as sibling communication, sibling comparisons, and parental differential treatment.


Indomethacin In Rheumatic Disease: A Clinical Assessment . . . . . . . . . . . . . . . • 603 Oxytocin and Sparteine Sulphate In Labour 603 An Historical Reunion Dinner . . . . . . . . .. 604 Diet, Hyperchoiesterollllmia and Coronary Heart Disease . . . . . . . . . . . . . . . . . . 604 Maternal Care In the Service of Mental Health 605 The Labelling of Toxic Substances In the Home 605 Acute Leuksemta and Phenylbutazone 605