High voltage circuit breakers (HVCBs) are essential components for reliability and resiliency of the power system, and it is crucial to optimize principles of condition monitoring for maintenance of this equipment. In this paper a novel methodology based on combination of HVCB's overall health index and expected aging curve is presented to provide an optimal scheduling of HVCB's maintenance. The overall health index of HVCB is acquired by conventional measurements, e.g. contacts dynamic resistance, drive motor current, etc. The methodology has been verified based on experimental tests that are implemented on a 110 kV HVCB. Based on the obtained results, the proposed method would increase the accuracy of HVCB's condition based maintenance scheduling, which will improve system reliability, ensure personnel safety, reduce the unplanned down time, and decrease the overall maintenance cost.


Since the time of Griesbach it has been generally recognized that the main problem of textual criticism in the New Testament is due to the existence of three distinct types of text, the Neutral, Western, and Syrian (or Antiochian). The great contributions of Westcott and Hort were the clear delineation of this problem and the establishment in considerable detail of the Neutral text. The Western text they only indicated in outline, and the Antiochian text was left with little further definition than that already provided by the Textus Receptus.


The screening of 30 substituted 1-hydroxyimidazoles as herbicides, anthelmintics, insecticides, bacteriostats, fungicides, coccidiostats and nematocides disclosed a broad spectrum of biological activity in all but two compounds. The most pesticidally active imidazoles carried an interdiazal benzenoid or heterocyclic aromatic ring substituent with a phenolic or potentially phenolic group attached thereto.


Behavioral finance puts in perspective the implication of an individual's inherent behavior impacting decision making. The present study bases itself on the concepts of investor finance and generational studies giving much better understanding of the domain. The domain of behavioral finance has pertinently become an independent and relevant domain in finance. Generational studies expound demographic study based on generation theories, divided into cohorts, with each cohort bearing specific characteristics. The study has been carried out to comprehend the inter generational relationship of behavioral biases across generational cohorts. The study was carried in Thane with 384 individuals across generational cohorts with age ranges from 18-55 years. Statistical analysis has been carried out to analyze the relational basis. Cohort characteristic linkage has been carried out to comprehend the basis of the statistical results. Behavioral categorization of cohorts Every societal


Soccer player's continuously suffering from several lower extremity injuries. Hamstrings muscle injury is one of them. The game of soccer is body contact and intermittent nature. Most of the hamstring's injury occurred due to less stretchable and strengthening ability of the muscles. Therefore, this injury appeared by non-body contact situation even though game has body contact difficulty. Muscle strength is one of the key factors in high performance and is an important indicator of the effectiveness of injury prevention in athletes [1,2]. However, one of the most used methods to assess muscle strength balance between dominant/ non-dominant and antagonist/agonist is isokinetic testing [2,3]. Therefore the sports scientist wants to develop a number of muscle strength methods especially lower limb strength. The hamstrings are a collection of muscles and their tendons at the back of the upper limb. The muscles bend the knee joint, adduct the leg, and extend the thigh to the rear end of the body. Strength of the hamstrings muscle alone is not the only main factor in injury prevention. The strength ratio of hamstring to quadriceps (H:Q) is necessary to provide sufficient development process for playing without injury. Quadriceps is naturally robust than the hamstring. So that, sometime this can overpower their hamstrings. This imbalance of hamstring to quadriceps strength ratio is often the reason of hamstrings injury [4,5]. Hamstring to quadriceps the highest torque strength ratio (H:Q) is one of the most usually assessed. To examine the functional capacity, the ratio of strength (H:Q) of agonist to antagonist knee muscles has been used [1]. Abstract


A new kind of torsion raicromirror with advanced vertical torsion comb driver is proposed and fabricated in silicon on insulator( SOI) wafers by combing with bulk micro machining and surface micro machining technology to improve the electromechanical performances and the optical properties. To evaluate the mechanical robustness and the electrical response , the electromechanical performances of the components are investigated by theory analysis and numerical simulation with finite element method (FEM) method and then the structures are optimized to improve the response speed and reduce the threshold voltage. According to the scalar scattering theory, a mathematical model, which describes the effects of the surface roughness on reflectivity and scattering, is constructed to analyze the optical properties of micromirrors. Then the surface roughness of micromirrors is measured by the atomic force microscope ( AFM). The theoretical and experimental studies manifest that the vertical torsion comb structures with folded beams by SOI wafer are much benefit to decreasing the threshold voltages of actuating the micromirror (making their tilting motion easier) and to enhancing the optical reflectivity of micromirror's surface.


The complex structure of plant cell walls resists chemical or biological degradation, challenging the breakdown of lignocellulosic biomass into renewable chemical precursors that could support future production of green chemicals and transportation fuels. Here, experimental and computational results reveal how molecular interactions between tetrahydrofuran (THF)-water and lignocellulose can identify this co-solvent pair and other co-solvents as being multifunctional or capable of synergizing multiple key mechanisms driving the breakdown of biomass into valuable chemical precursors. Molecular simulations reveal that lignin globules expand in THF-water, an excellent "theta" solvent, dissociating both from themselves and from cellulose. The expansion of the lignin molecules in THF-water further exposes inter-unit linkages, rendering them susceptible to acid-catalyzed fragmentation by cleavage of aryl-ether bonds. Nanoscale infrared sensors confirm co-solvent mediated molecular rearrangement of lignin in the cell wall of micron-thick hardwood slices and track the disappearance of lignin. At bulk scale, dilute acid pretreatment of biomass in a co-solvent mixture liberates hemicellulose and depolymerized lignin from cellulose, allowing unfettered access of cellulolytic enzymes that sustain high rates of cellulose hydrolysis to glucose without enzyme deactivation. Through this multi-scale analysis, synergistic mechanisms can be identified for other multifunctional co-solvents portending a paradigm shift towards first principles design of future biomass deconstruction methods in order to realize lower cost fuels.


We analyze the effect of companion stars on the bulk density of 29 planets orbiting 15 stars in the Kepler field. These stars have at least one stellar companion within 2″, and the planets have measured masses and radii, allowing an estimate of their bulk density. The transit dilution by the companion star requires the planet radii to be revised upward, even if the planet orbits the primary star; as a consequence, the planetary bulk density decreases. We find that if planets orbited a faint companion star, they would be more volatile-rich, and in several cases their densities would become unrealistically low, requiring large, inflated atmospheres or unusually large mass fractions in an H/He envelope. In addition, for planets detected in radial velocity data, the primary star has to be the host. We can exclude 14 planets from orbiting the companion star; the remaining 15 planets in seven planetary systems could orbit either the primary or the secondary star, and for five of these planets the decrease in density would be substantial even if they orbited the primary, since the companion is of almost equal brightness as the primary. Substantial follow-up work is required in order to accurately determine the radii of transiting planets. Of particular interest are small, rocky planets that may be habitable; a lower mean density might imply a more volatile-rich composition. Reliable radii, masses, and thus bulk densities will allow us to identify which small planets are truly Earth-like.


Achieving strong interactions between individual photons enables a wide variety of exciting possibilities in quantum information science and many-body physics. Cold atoms interfaced with nanophotonic structures have emerged as a platform to realize novel forms of nonlinear interactions. In particular, when atoms are coupled to a photonic crystal waveguide, long-range atomic interactions can arise that are mediated by localized atom-photon bound states. We theoretically show that in such a system, the absorption of a single photon can change the band structure for a subsequent photon. This occurs because the first photon affects the atoms in the chain in an alternating fashion, thus leading to an effective period doubling of the system and a new optical band structure for the composite atom-nanophotonic system. We demonstrate how this mechanism can be engineered to realize a single-photon switch, where the first incoming photon switches the system from being highly transmissive to highly reflective, and analyze how signatures can be observed via non-classical correlations of the outgoing photon field.


The general opinion and current scientific evidence highlight the link between red meat consumption and the development of non-communicable diseases (NCDs). We explored the determinants of the intention to consume red meat in relation to the risks of developing NCDs in Senegal with a special focus on popular "dibiterie" meat (braised meat) consumed in Dakar, Senegal. Building on the theory of planned behaviour as a theoretical framework, we used a structured questionnaire to collect data on the knowledge of consumers regarding the risk of NCDs from consuming meat. The survey involved 478 people randomly selected from households in the Dakar region. Data collected was analysed by performing the calculation of the dibiterie meat quantities consumed and frequencies of consumption, analyses of the principal components, binary logistic regression, and multiple hierarchical regression. Results show that dibiterie meat is mainly a dietary supplement for the population. The convenience, the social pressure, and quality indicators such as producer expertise and health perceived a link between meat consumption and NCDs; gender and age predicted the intention to consume dibiterie meat in the households of the Dakar region. This study provides a theoretical basis for the development of incentive-based interventions aiming to promote a balanced diet and healthy eating habits. Nutrition education and the use of social media have been raised as important in risky meat consumption behaviour change.


The study case is situated in Calarasi County, Romania, near Danube river. The sprinkler irrigation arrangement serves the area of 1018.67 ha, useful, net irrigated area. The sprinkler irrigation arrangement comprises fixed irrigation equipment consisting of 16 central irrigation pivots equipped with nozzle ramps for water spray, the pivots are supplied with water through a network of underground pipes, pumping station, water source the Privalul Tinoasa channel fed from the Danube River The Privalul Tinoasa channel will be cleared and re-profiled, having the role of water accumulation basin that will ensure the aspiration for the designed pumping station. Numerical modelling was performed using the program MIKE11. MIKE 11 is a user-friendly, fully dynamic, one-dimensional modelling tool for the detailed analysis, design, management and operation of both simple and complex river and channel systems. With its exceptional flexibility, speed and user-friendly environment, MIKE 11 provides a complete and effective design environment for engineering, water resources, water quality management and planning applications. The Hydrodynamic (HD) module is the nucleus of the MIKE 11 modelling system and forms the basis for most modules including Flood Forecasting, Advection-Dispersion, Water Quality and Non-cohesive sediment transport modules. The MIKE 11 HD module solves the vertically integrated equations for the conservation of mass and momentum, i.e. the Saint-Venant equations. The input data are: area plan with location of cross sections; cross sections topographical data and roughness of river bed; flood discharge hydrograph. Advanced computational modules are included for a description of flow over hydraulic structures, including possibilities to describe the structure operation.


Objective To establish a method for the determination of three synthetic sweeteners(sodium cyclamate, saccharin sodium, and acesulfame) in fruits by ultra-high pressure liquid chromatography-mass spectrometry (UPLC-MS/MS). Methods The synthetic sweeteners were extracted with water, separated on a reversed phase C18 column using acetonitrile-0.02mol/L ammonium acetate as mobile phase, and then detected by UPLC-MS/MS under multiple reaction monitoring (MRM) mode. Results The method showed a good linearity for all the analysts over the range of 10~600 μg/L with r≥0.995. The detection limits of sodium cyclamate, saccharin sodium and acesulfame were 0.8、5.0 μg/kg and 1.0 μg/kg, respectively. The recoveries ranged from 74.9% to 111.2% at two spiked concentrations with the relative standard deviations lower than 8%.Conclusion This established method has the advantages of easy to operate, fast to perform, with high sensitivity and accuracy, and it is suitable for detection of sodium cyclamate, saccharin sodium and acesulfame in fruits.


This contribution presents the ground calibration campaign of the HIFI Flight Model instrument conducted at the SRON-Groningen premises. This campaign has been conducted over more than a year and a half, with a core period of 9 months where the complete flight model was available in the laboratory. The calibration of the instrument has been organized according to four main topics: i) spectral calibration, ii) beam characterisation, iii) photometry calibration, iv) stability. We present here the strategy used in each of these activities and give the first outcomes of the campaigns, especially in the perspective of the future calibration of the astronomical data, and how these results will be propagated onto the flight early and routine activities. The characterisation of the spectral properties of an heterodyne instrument is a key issue for the final frequency calibration of the astronomical data. The spectral behaviour of the full instrument will be highly related to the performances of the Local Oscillator Unit (LO) as the signal produced by this latter has implications at several levels of the detection chain. First of all, the master oscillator (which has an accuracy of 1 part in 10 7 ) will provide the lock frequency to the High-Resolution Spectrometer (HRS) internal oscillators, as well as to the internal comb used in the Wide-Band Spectrometer (WBS). It therefore drives the absolute frequency calibration accuracy offered by the spectrometers. Because the LO signal is not a purely monochromatic line, it will degrade the spectral properties of the instrument, both at the level of spectral responses (resolution element shape, spurious response in the down- converted product) and spectral signals (spontaneous emission from the LO). They are described in the following sections. A. Spectral Response The spectral response of the instrument is the combination of the responses of the spectrometers themselves, and of that of the LO injected line. The objectives of the tests conducted were as follows: • Verify the absolute frequency resolution of the instrument


Based on the analysis of development characteristics of Surennuoer fault and recovering of ancient tectonic stress,vertical open degree of Surennuoer fault of K1d caprock in four tectonic movement periods was studied from the angle between the orientation maximum principal compressive stress and the strike direction of Surennuoer fault.The results show that the vertical open degree of Surennuoer fault is different in different tectonic movement periods,the vertical open degree in southwest of Surennuoer fault is different from that in northeast of Surennuoer fault.By the study of the relation between vertical open degree of Surennuoer fault in different tectonic movement period and the expulsion oil-gas history of K1n1 source rock,it was considered that the third tectonic movement occurring in the later of K2y sedimentation period was rightly the period of a lot of oil-gas expelled from K1n1 source rock.Vertical open of Surennuoer fault are the main transporting pathway of oil-gas migrating from K1n1 source rock to K1n2 reservoirs,and its open degree in K1d1 is not so high so that it is favorable for oil-gas to accumulate and preserve in K1n2.This is the important cause that there are a lot of hydrocarbon to accumulate in K1n2.But vertical open degree in southwest of Surennuoer fault is lower than that in northeast of Surennuoer fault in this tectonic movement period.The oil-gas accumulation and preservation conditions in southwest of Surennuoer fault are better than that in northeast of Surennuoer fault.This is the important reason why there are more industrial oil-gas accumulations in southwest of Surennuoer fault than in southeast of Surennuoer fault.


Based on the torque model of permanent magnet synchronous generator(PMSG) and the theory of the direct torque control(DTC) ,the DTC strategy is utilized for controling the PMSG in the direct-drive wind power system.It is discussed how to detect the rotor initial position and to construct the vector table under gengerator model,and a DTC system without the position sensor is proposed.The key control part of the system is consisted of DSP320LF2812 and the main power circuit includes PMSG and the power convertor.The experimental results indicate the feasibility and effectiveness of the proposed strategy.


OBJECTIVE
The "red complex," composed of Bacteroides forsythus, Porphyromonas gingivalis, and Treponema denticola, is implicated in severe forms of periodontal diseases. The purpose of this study was to assess the occurrence of the red complex in root canal infections through the use of a sensitive technique-the 16S rDNA-directed polymerase chain reaction (PCR).

STUDY DESIGN
Samples were obtained from 50 necrotic pulps with periradicular pathosis. Ten cases were diagnosed as acute periradicular abscesses. DNA was extracted from the samples and analyzed with a PCR-based identification assay.

RESULTS
At least 1 member of the red complex was found in 33 of 50 cases. T denticola, P gingivalis, and B forsythus were detected in 44%, 30%, and 26% of the cases, respectively. The red complex was found in 4 of 50 cases. No particular signs or symptoms were associated with the presence of these bacterial species.

CONCLUSIONS
Despite what is indicated in reports with respect to marginal periodontitis, red complex bacteria-either singularly or collectively-was not associated with any particular pattern of clinical symptoms. However, because the bacterial species from the red complex are recognized oral pathogens, their occurrence in root canal infections suggests that they may play a role in the pathogenesis of periradicular diseases.


Received: 16 April 2017 Final Accepted: 18 May 2017 Published: June 2017 Background : to evaluate the response rate , survival and safety of the combination of temozolamide and whole brain radiotherapy in breast cancer patients with previously untreated brain metastases Patients and Methods:40 patients with brain metastases were divided in two groups Control arm(A): patients received whole brain radiotherapy(WBRT) at a dose of 30 Gy in 10 daily fractions over 2 weeks. TMZ plus WBI arm (B): patients treated with (WBRT) at a dose of 30 Gy in 10 daily fractions over 2 weeks concomitant with temozolamide. The primary endpoint was overall response (OR) Secondary endpoints were progression free survival (PFS) and overall survival ( OS) Results: Patients who received WBI and TMZ had an overall response of 45% compared with 40% in WBI alone with no statistically significant difference. Brain metastasis progression was observed in 45% in the control group(A) versus 15% in group B with a statistically significant difference (p=0.038) . Median progression free survival ( PFS) was 6 months in group A but 9.5 in group B with non significant difference. One year progression free survival was 37.5% in group A versus 45% in group B . One year overall survival was 33.3% in group A versus 47.8% in group B . Median overall survival was 7 months in group A versus 11 months in group B with non-significant difference. Most of patients had tolerable side effects and recovered eventually. Conclusion: Although, the combination of WBRT and TMZ was safe and appeared to improve local control , OS and PFS of BMs from breast cancer in this study, this improvement was nonsignificant, and further studies with larger number of patients are needed to get significant results.


Isotropic yield surfaces of bcc and fec metals have been simulated with TBH theory.Using the five-dimensional stress space proposed recently by Lequeu et al.,the yield subsurfaces on any two of the three shear stresses can be considered as the inscribed circles of their corresponding subsurfaces on n plane.Based on this concept,Hershey,Hosford and Hill (HHH) yield func- tion has been transformed into the formula where the parameters are uniquely determined by two crystallographic factors:the mean Taylor factor in plane strain (M_p) and the critical shear stress (τ_) on slip systems.


Selective mutism was first described more than 100 years ago. It belongs to an heterogeneous group of conditions that share in common the presence of anomalies in social behavior starting during the developmental period. In DSM-5, it has been classified in the category of Anxiety Disorders. We present a clinical case of a patient that was referred to our child and adolescent Mental Health Unit due to a lack of speech in school and social contexts in spite of speaking with apparent normality in the presence of closest relatives, also accompanied by school failure. We present some of the general characteristics of the disorder: risk factors, diagnostic features according to the most important current classification systems and treatment strategies. We also describe the case, including clinical interviews, analysis of the information shared by the adoptive mother, exploration of the mental state, summary of neuropsychological explorations and school reports, and provide a final discussion.


Sulfuric acidwas used to leach the phosphorus in the high-phosphorus iron ore concentrate after magnetic roasting and separation(iron grade 54.92%,phosphorus content 0.83%),and the ultrasonic wave was utilized to intensify the effects.The results showed that: with the increase of leaching time,the dephosphorization rate decreased gradually,and 60 min was the best time.The iron grade fluctuated to some extent while the recovery dropped consistently,which was over 92% as a whole.With the increase of pulp density,the remaining phosphorus went up as well.Under the condition of 6% pulp density,the results of dephosphorization by ultrasonic wave were significant,and the remaining phosphorus was under 0.24%,while the recovery of iron rose steadily,from minimum 91.89% to maximum 95.50%.


This work is the update of a chapter of the Dionysian thesis in the Middle Ages, defended in the Doctorate of Social Sciences, Rene Descartes University, Paris V, Sorbonne, in the winter of 1995, under the guidance of Michel Maffesoli. We follow the clues that can stimulate an interpretation of contemporary tendencies in Brazilian culture, including urban music, fashion, advertising, cinema and television. It is a study that suggests pertinent approaches to the researches on communication and language, firstly because it deals with the narratives that translate and performatizam the daily, telenovelas. We prefer, above all, a look at the modes of communication and sociability, for the interactions and connections experienced by individuals in the information age.


Since the upsurge of the so-called 'third wave' of right-wing extremism many researchers have addressed the question to what extent the success of these kind of parties is grounded in diffuse feelings of political alienation. Unfortunately these inquiries did not produce an unequivocal answer. As a matter of fact some of the findings are clearly contradictory. In the first part of this article we will argue that these divergences are largely attributable to alternative conceptualisations and operationalisations. In the second part of the article we will question the validity of the conventional causal direction, namely from 'feelings of alienation' to 'voting for an extreme-right wing party'. We will show that it might be very fruitful to reverse this relationship. In this respect we will test to what extent repeated voting for an extreme-right wing party such as the Vlaams Blok actually produces feelings of 'external political powerlessness'. Paper prepared for presentation At the ECPR Joint Sessions of Workshops Workshop 14: 'Democracy and the New Extremist Challenge in Europe' Institut d'Etudes Politiques de Grenoble, France 6-11 April 2001


A new procedure for deriving integrable Hamiltonians and their constants of the motion is introduced. We term this procedure the truncation program. Integrable Hamiltonians occurring in the truncation program possess constants of the motion which are polynomials in a perturbation parameter e. The relationship between this program and the Whittaker program in two degrees of freedom is discussed. Integrable Hamiltonians occurring in the Whittaker program (a generalization of Whittaker's work) possess constants of the motion which are polynomials in the momentum coordinates. Many previously known integrable Hamiltonians are derived. A new family of integrable double resonance Hamiltonians and a new family of integrable Hamiltonians of the form (p21+p22)/2+V(q1, q2) are derived.


With the seasonal higher degree of criminal cases committed in some farming herding regiments of Xinjiang corps,the tasks to crack down on crimes and to defend on them are becoming more difficult.The different economic running models between corps and non-corps regions in Xinjiang lead to a variety of contradictions,resulting in higher degree of public security problems in corps.The essay puts forward some countermeasures to cope with these problems: to waken the legal awareness of the working staff in these farming herding regiments;to increase the number of police in these regiments;to strengthen the construction of the security offices in the fundamental departments;and to enhance mass prevention work against crimes.


The invention discloses a single longitudinal mode laser device capable of switching wavelengths. The laser device comprises a 980nm pump laser, a 980nm 3dB first coupler, 980nm/1550nm first wavelength division multiplexer and second wavelength division multiplexer, an electrically controlled optical switch, a group of optical fiber gratings with different center wavelengths, a second coupler, an L-waveband 3dB third coupler, and a monitoring system connected with the second coupler, wherein the pump laser is connected with the first coupler through optical fiber; the first coupler is respectively connected with the first wavelength division multiplexer and the second wavelength division multiplexer through the optical fiber; the two wavelength division multiplexers are connected with each other through EDF (Erbium-Doped Fiber) which is used as a gain medium; the first wavelength division multiplexer is successively connected with the second coupler and the third coupler; the second wavelength division multiplexer is connected with the electrically controlled optical switch through an optical fiber and the electrically controlled optical switch is respectively connected with each optical fiber grating with different center wavelengths.


Objective
To analyze the relevant factors influencing 18F-FDG uptake in the primary lesion of breast invasive ductal carcinoma (BIDC).

Methods
A total of 160 female patients underwent 18F-FDG PET/CT examination from 2010 to 2015 and breast lesions were revealed. Lesions were divided into benign group (n=118) and malignant group (n=49, BIDC) according to pathological results. Kruskal-Wallis H test and Mann-Whitney u test were performed to compare SUVmax of the two groups, and to investigate the relationship between the SUVmax of breast malignant lesion and patients′ age as well as clinical pathological parameters including T stage, lymphatic vessel invasion, nuclear grade, route of metastasis, ER, PR, HER2 and Ki-67 expression, and subtype of breast cancer. The diagnostic efficiency of 18F-FDG PET/CT in differentiating benign and malignant breast lesions was analyzed using ROC curve analysis.

Results
The SUVmax of BIDC was 6.09(3.88, 9.26), higher than that of breast benign lesion (1.35 (0.95, 2.35); u=341.0, P 2.0 cm, the optimum cutoff values of SUVmax were >2.60, >1.71 and >3.97, respectively. When the optimum cutoff values of SUVmax for breast lesions with the maximum diameter ≤2.0 cm were selected as >1.71 and >2.60, the Youden indexes were 0.66 and 0.61(z=0.566, P>0.05). When the optimum cutoff values of SUVmax for breast lesions with the maximum diamter >2.0 cm were selected as >3.97 and >2.60, the Youden indexes were 0.89 and 0.81(z=0.748, P>0.05).

Conclusions
T stage, lymphatic vessel invasion, nuclear grade, route of metastasis and Ki-67 expression of BIDC influence the uptake of 18F-FDG by tumor tissues. The SUVmax of the primary lesion of BIDC is related to the size of lesion, and thus the diagnostic threshold of SUVmax should be decreased appropriately for small lesions.

Key words:
Carcinoma, ductal, breast; Tomography, emission-computed; Tomography, X-ray computed; Deoxyglucose


AZD7442 (tixagevimab/cilgavimab) is a combination of neutralizing monoclonal antibodies (mAbs) that bind to distinct epitopes on the SARS-CoV-2 spike protein, with neutralization activity against variants including Omicron. In the Phase 3 TACKLE study, AZD7442 significantly reduced severe disease progression or death and was well-tolerated through Day 29. Viral evolution during treatment has the potential for resistance selection, such as variants exhibiting reduced mAb binding. We report genotypic analysis and phenotypic characterization of variants identified over 15 days after AZD7442 treatment in TACKLE.

 In TACKLE (NCT04723394), non-hospitalized adults with mild to moderate COVID19 were randomized and dosed ≤7 days from symptom onset with a single 600-mg AZD7442 dose (2 consecutive intramuscular injections, 300 mg of each antibody; n=452) or placebo (n=451). Next-generation sequencing of the spike gene was performed on SARS-CoV-2 reverse-transcription polymerase chain reaction–positive nasal swabs (at baseline and Days 3, 6, and 15). SARS-CoV-2 lineages were assigned using spike nucleotide sequences. Amino acid substitutions, insertions, and deletions were analyzed at allele fractions (AF, % of sequence reads represented by mutation) ≥25% and 3–25%.

 Baseline spike sequences were available from 744 participants (82.4%) (AZD7442, n=380; placebo, n=364); 87% of sequences corresponded to variants of concern/interest; these were balanced between AZD7442 and placebo groups (Table 1). Treatment-emergent (post-dosing) viral variants were rare, with 11 (4.5%) AZD7442 and 3 (1.3%) placebo participants showing the emergence of ≥1 mutation at tixagevimab/cilgavimab binding sites, with an AF ≥25% (Table 2). At AF 3–25%, treatment-emergent viral variants in the AZD7442 binding site were observed in 16 (6.6%) AZD7442 and 15 (6.5%) placebo participants.

 Following AZD7442 treatment, low levels of SARS-CoV-2 variants bearing mutations at tixagevimab/cilgavimab binding sites were identified. These data indicate that combination of two antibodies creates a high genetic barrier for resistance, supporting the use of mAb combinations that bind to distinct epitopes for the treatment of COVID-19.

 Gustavo H. Kijak, PharmD PhD, AstraZeneca: Employee|AstraZeneca: Stocks/Bonds Bahar Ahani, BSC, AstraZeneca: Employee|AstraZeneca: Stocks/Bonds Douglas Arbetter, MPH, AstraZeneca: Employee|AstraZeneca: Stocks/Bonds Tyler Brady, MS, AstraZeneca: Employee|AstraZeneca: Stocks/Bonds Fernando Chuecos, BS, AstraZeneca: Employee|AstraZeneca: Stocks/Bonds Vancheswaran Gopalakrishnan, PhD, AstraZeneca: Employee|AstraZeneca: Stocks/Bonds Tiffany L. Roe, B.S., AstraZeneca: Employee|AstraZeneca: Stocks/Bonds Nicolette Schuko, MS, AstraZeneca: Employee|AstraZeneca: Stocks/Bonds F.D. Richard Hobbs, FMedSci, AstraZeneca: Grant/Research Support|AstraZeneca: Principal investigator|NIHR Applied Research Collaboration, Oxford Thames Valley: Director|Oxford BRC and NIHR MedTech: Investigator|UKRI and NIHR: Grant/Research Support Francisco Padilla, MD, Amgen: Grant/Research Support|Amgen: Personal fees|AstraZeneca: Grant/Research Support|AstraZeneca: Personal fees|Boehringer Ingelheim: Grant/Research Support|Boehringer Ingelheim: Personal fees|Ferrer: Grant/Research Support|Ferrer: Personal fees|Kowa: Grant/Research Support|Kowa: Personal fees|Medix: Grant/Research Support|Medix: Personal fees|Merck Sharp and Dohme: Grant/Research Support|Merck Sharp and Dohme: Personal fees|Novartis: Grant/Research Support|Novartis: Personal fees|Pfizer: Grant/Research Support|Pfizer: Personal fees|Sanofi: Grant/Research Support|Sanofi: Personal fees|Servier: Grant/Research Support|Servier: Personal fees|Silanes: Grant/Research Support|Silanes: Personal fees Elizabeth J. Kelly, PhD, AstraZeneca: Employee|AstraZeneca: Stocks/Bonds Hugh Montgomery, MD, AstraZeneca: Advisor/Consultant|Millfield Medical Ltd: Advisor/Consultant|UK National Institute for Health Research's Comprehensive Biomedical Research Centre at University College London Hospitals: Grant/Research Support Katie Streicher, PhD, AstraZeneca: Employee|AstraZeneca: Stocks/Bonds.


Preface 1. Fish as Food 2. Coastal Ecology 3. Biology of Culturable Species 4. Hydrology of Coastal and Deltaic Areas 5. Tides and Tidal Computations 6. Water Waves and their Computation 7. Mechanics of Sediment Transport and Coastal Fluvial Processes 8. River Protection Works 9. Design of Brackish Water Pond System 10. Sedimentation Problems in Brackish Water Fish Farms and Engineering Measures for its Migration 11. Basic Principles of Aquaculture Practices 12. Different Culture Techniques 13. Post Harvest Technology Index.


1 Rosenbach M, Hsu S, Korman NJ et al. Treatment of erythrodermic psoriasis: from the medical board of the National Psoriasis Foundation. J Am Acad Dermatol 2010; 62: 655–662. 2 Esposito M, Mazzotta A, de Felice C, Papoutsaki M, Chimenti S. Treatment of erythrodermic psoriasis with etanercept. Br J Dermatol 2006; 155: 156–159. 3 Takahashi MDF, Castro LGM, Romiti R. Infliximab, as sole or combined therapy, induces rapid clearing of erythrodermic psoriasis. Br J Dermatol 2007; 157: 828–831. 4 Santos Juanes J, Coto-Segura P, Mas-Vidal A, Galache Osuna C. Ustekinumab induces rapid clearing of erythrodermic psoriasis after failure of antitumour necrosis factor therapies. Br J Dermatol 2010; 162: 1144– 1146. 5 Wang T-S, Tsai T-F. Clinical experience of ustekinumab in the treatment of erythrodermic psoriasis: a case series. J Dermatol 2011; 38: 1–4.


Web servers are normally situated in a highly structured network architecture where they allow access to the external internet through backbones. However, the Application Layer DDoS attacks are real threats for those web servers, particularly for the organizational web servers. The intruder transmits the attack requests using legitimate HTTP requests, making it difficult for the detection systems to classify the attack traffic and legit traffic. This study proposes a novel model for identifying and classifying such attack traffics using semi-supervised machine learning algorithms. The model is applied to the CICIDS 2017 Dataset, which contains Application Layer DDoS attack characteristics. The model is created by using correlation analysis to select features and reduce the dataset's dimension, then applying K-Means Clustering to an unlabeled feature-selected dataset to generate clusters, which are then labeled based on their nature (Benign or Attack label), and finally feeding the labeled clustered dataset to Support Vector Machine to train and test the model. The model successfully classifies web traffic based on its nature (Benign or Attack traffic) and on evaluation the model outperforms on the tested dataset when compared to the available classification algorithms.


It has been proposed that angio-immunoblastic lymphadenopathy is a non-neoplastic hyperimmune state with excess B-cell proliferation (Lukes & Tindle, 1975). More recently an associated defect of T-cell regulation has been suggested (Rudders & De Lellio, 1977). The condition is manifest clinically by hepatosplenomegaly, dysproteinaemia, often of a polyclonal nature, and generalized lymphadenopathy (Frizzera et a l , 1974). There is often a Coombs positive haemolytic anaemia and a non-specific picture of night sweats, weight loss and skin rash. Histologically the disease is characterized by an immunoblastic proliferation accompanied by arborizing blood vessels and amorphous interstitial eosinophilic deposits as seen on haematoxylin and eosin staining. W e describe here a case of immunoblastic lymphadenopathy which is of special interest owing to the hitherto unreported association with lupus erythematosus cells. A 58-year-old man presented with a 4-week history of increasing lassitude, intermittent fever, night sweats, weight loss and confusion. There was no past history of significant illness or of exposure to toxic substances. He was anaemic with petechial haemorrhages in the oral mucous membranes and on the limbs. There was generalized lymphadenopathy and hepatosplenomegaly with wasting of the limbs and distal muscle weakness. A peripheral neuropathy was confirmed by absent deep tendon reflexes and impaired pin-prick and light touch sensation below the knees. Laboratory investigation revealed a dysproteinaemia with polyclonal elevation of the IgG and IgM fractions. Repeated LE cell preparations were positive (Fig lc) but the DNA binding percentage was normal. The C3 fraction of serum complement was reduced, with the C4 fraction at the lower limit of normal. Rheumatoid factor was detected a t a titre of 1/160. Toxoplasma dye test titre was 1/64 but toxoplasma specific IgM was not detected. Viral studies were negative. No Bence Jones protein was detected in the urine. Bone marrow aspiration and trephine biopsies revealed diffuse infiltration of the marrow by plasmacytoid cells and mature plasma cells with reduction of the other haemopoietic elements. Histology of a cervical lymph node showed effacement of the normal architecture by proliferating blood vessels, lymphocytes, plasmacytoid cells, plasma cells and large immunoblasts (Fig 1) , the features being typical of angio-immunoblastic lymphadenopathy. Treatment with high dose steroids was commenced and he was given red cell and platelet support. Regression of the lymphadenopathy and hepatosplenomegaly occurred but an autoimmune haemolytic anaemia developed, which responded to azathioprine. Steroids were subsequently withdrawn and he remained in remission for 3 weeks, taking azathioprine 100 mg/d. Serum immunoglobulin levels fell to within the normal range. Bone marrow depres-


The opening to the outside world provides the opportunity for Central China to speed up its economic growth.At the same time,China's Central Area needs to make full use of its various advantages and important strategic opportunities to upgrade its level of opening to the outside world and to continuously optimize its environment of development by technical transfer in order to ensure the realization of quickening the economy of Central China.


Procedures are suggested to insure that computer-calibrated optical emission spectrometers will analyze unknown samples with the same accuracy as older instruments that used hand-drawn curves.


Abstract This paper reviews the literature on the evacuation demand problem, with an emphasis on the impact of various modelling approaches on network‐wide evacuation performance measures. First, a number of important factors that affect evacuee behaviour are summarized. Evacuation software packages and tools are also investigated in terms of the demand generation model they use. The most widely used models are then selected for performing sensitivity analysis. Next, a cell‐transmission‐based system optimal dynamic traffic assignment (SO‐DTA) model is employed to assess the effects of the demand model choice on the clearance time and average travel time. It is concluded that evacuation demand models should be selected with care, and policy makers should make sure the selected demand curve can replicate real‐life conditions with relatively high fidelity for the study region to be able to develop reliable and realistic evacuation plans.


The major issues that affect a firm's revenue is to get the price right. Price plays an important role since it is one of the strategic marketing variables that have direct impact on sales revenue or financial performance. However, the studies of pricing within the marketing discipline were very few particularly in hotel industry. This study was to ascertain the implications of hotel room pricing strategies adopted by 5 star-rating hotels in Malaysia with regards to their financial performance. Apart from that, this study was also aimed to examine the relationship between hotel pricing strategy, financial performance and external environment as moderating variable. The pricing strategies construct were derived from various articles on pricing in services industry and integrated according to four dimensional measures of cost-based, competitive, differential and psychological pricing strategy. Meanwhile, financial performance was measured by means of average room rate (ARR), occupancy percentage and revenue per available rooms (RevPAR). Samples for this study comprised of 72 hotels (5-star) with 100 rooms and above throughout Malaysia in which hotel manager was selected as a respondent. The statistical analyses used involved Multiple Regression, Hierarchical Regression and Moderated Regression analysis. Results indicated that cost-based pricing and differential pricing have a negative relationship with hotel financial performance, whereas competitive pricing and prestige pricing showed a positive relationship. This supported the notion that, for example; when a hotel that used cost-based pricing increased their room rates, it will lead to decrease in their financial performance or vice versa. Generally, the relationship between pricing strategy and financial performance were supported since the overall model showed that it was significant. Overall, the proper selection of pricing strategy by the hotel managers may lead the organization to their targeted revenue or income. Furthermore, it would also profitable for a hotel organization to implement more than one pricing strategy in their marketing strategy.


A simple, but very reproducible, method for measuring the relative specificity of ribulosebisphosphate carboxylase-oxygenase for CO2, as opposed to O2, is described. The method uses [1-14C]ribulose bisphosphate as substrate and combines the advantages of supplying both gaseous substrates from the gas phase with HPLC separation of the labelled products. Volumetric or gravimetric accuracy is not required at any stage of the procedure and variations in ionic strength and pH have little effect on the measurements. This leads to excellent reproducibility without the need for normalisation. The average standard deviation was 1.3% of the measured CO2/O2 specificity. Use of very low ribulose bisphosphate concentrations ensures that the gaseous substrates cannot be depleted appreciably during the reaction and enhances the attractiveness of the procedure for measurements with crippled mutant enzymes. The procedure's ability to resolve small differences in relative specificity is demonstrated by its easy detection of the 5% increase in specificity that accompanies substitution of four residues at positions 338-341 of the cyanobacterial large subunit with the analogous higher-plant residues. This resolving power is essential for detecting small differences in the specificities of higher-plant ribulosebisphosphate carboxylases which may be the signature of continuing evolutionary refinement.


Range readiness is an outdated practice forcing rangeland managers into management situations that are detrimental to the natural resource base. DO:10.2458/azu_rangelands_v27i2_perryman


The ongoing development of collaborative robots (cobots) bears great potential for assembly processes by enabling new possibilities of task allocation between humans and machines. A detailed, empirically based evaluation of how cobots can live up to these possibilities in industrial practice is still missing in the manufacturing literature. In this paper some of the existing shortcomings -referred to as "the productivity gap" ̶ in current assembly automation processes are discussed. To cope with this gap, adaptive human-cobot task sharing is proposed and implemented as a complementary task allocation model. Its potential to increase productivity and flexibility in new and existing assembly applications is evaluated.


In this paper we analyze the classical limit of the Nelson model with cutoff, when both non-relativistic and relativistic particles number goes to infinity. We prove convergence of quantum observables to the solutions of classical equations, and find the evolution of quantum fluctuations around the classical solution. Furthermore, we analyze the convergence of transition amplitudes of normal ordered products of creation and annihilation operators between different types of initial states. In particular, the limit of normal ordered products between states with a fixed number of both relativistic and non-relativistic particles yields an unexpected quantum residue: instead of the product of classical solutions we obtain an average of the product of solutions corresponding to varying initial conditions.


Summary: Isolated Langendorff-perfused rat hearts set up to allow measurement of mechanical myocardial function (according to Bardenheuer and Schrader) were subjected to 60 min of global ischemia (gI). The hearts were perfused with a modified Krebs-Henseleit solution (KHS; control group) or KHS with desipramine (DMI group) 100 nM. Extracellular concentrations of K+, Na+, and H+ were determined using ion-selective membrane polyvinyl chloride (PVC) minielectrodes. The noradrenaline (NA) release was estimated by analyzing the NA overflow during a 10-min reperfusion period, using high pressure liquid chromatography (HPLC). Control hearts and DMI-treated hearts showed no differences in mechanical performance prior to gI. In control hearts, the onset of gI resulted in a rapid triphasic [K+]e accumulation (an increase from 4.25 ± 0.25 to 8.76 ± 0.37 mmol/ L during the first 3.5 min, a decrease to 8.06 ± 0.34 mmol/ L until the seventh min, and a further increase to 33.0 ± 2.42 mmol/L at 60 min), a rapid increase in [H+]e (45.9 ± 2.3 to 1314.5 ± 214 nmol/L during 23 min), and a slight initial increase of [Na+]e (138.8 ± 0.4 to 141.9 ± 0.8 mmol/L within 8 min) followed by a long-lasting decrease (119.1 ±4.5 mmol/L at 60 min). Treatment with DMI had only slight effects on ionic redistribution during the course of ischemia. The [K+]e and [H + ]e accumulation tended to be diminished, whereas [Na+]e values were slightly higher in the course of gI compared to the control group. The ischemia-induced NA overflow was found to be significantly lower in DMI-treated hearts (148.9 ± 19.1 versus 226.0 ± 25.0 ng/g heart/5 min in control hearts), but in both experimental groups the estimated values of extracellular NA after 60 min of gI were in a range known to cause cellular necrosis (> 1 μmol/L). In conclusion, the results of this study indicate that (a) the isolated rat heart preparation represents a suitable model to determine changes of extracellular ion concentrations during ischemia, (b) the slight influences of DMI on the ion redistribution during gI are mainly due to an unspecific membrane stabilizing effect, and (c) therefore cannot explain the reduction of NA release following DMI application


Based on one-dimensional wave theory,the response of displacement and s peed and acceleration about bolt in d ifferent restriction are concluded.At the sa me time,the relation between wave sp eed and basic frequency and bolt length is found out.The response curve of acceleration in different state is tested at la boratory.


First published in The Sport and Exercise Scientist, February 2020, Issue 63. Published by the British Association of Sport and Exercise Sciences – www.bases.org.uk.


In view of the importance of this subject, comparatively little has been reported regarding the histogenesis of the typical cells of the rheumatic myocardial lesions first described by Aschoff. 1 On the other hand, many investigators have directed their attention to the etiology and specificity of the Aschoff body. Most investigators 2 have agreed that the responsible organism is the Streptococcus viridans of Schotmuller, and that the lesions are specific for rheumatic fever. Thalheimer and Rothschild, 3 however, report finding typical Aschoff bodies in cases of chorea without rheumatic history. So far as we are aware their findings have not been confirmed, although the etiologic factor is said to be the same for both diseases. Workers on the subject have either accepted Aschoff's original theory that the cells are "adventitial wandering cells," or they believe that these cells arise from the intramuscular connective tissue cells of the locality of the lesions. Aschoff (cited


The theory of economies of growth implies chasing urban growth is a process of pursuing economies of growth. Realization of economies of urban growth calls for good growth policies, right idea of growth strategy, learning and imitation, especially imagination and innovation. To make urban growth policies, we need to be guided by the theory of growth economies to break through the thinking mode that takes scale as the criterion to decide urban development. To make urban growth strategy, we need for discernment of super-competition and construction of small ecosystem. Institutional innovation is the essential to urban development.


Existing research assumes but does not investigate accounting technology professionals' (ATPs) motivation. ATPs motivations matter because of the instability and ubiquity of accounting technologies, and, ATPs boundary spanning role between accounting artifacts and computing technologies. Positivist and critical theory research make strong assumptions about, but leave largely uninvestigated, ATPs motivations. Self-determination theory (SDT), which originates in humanistic psychology, offers an unexplored alternative theory of ATP motivation. SDT suggests a set of propositions for proactively engaging ATPs in self-motivated, socially meaningful activities that enhance ATPs well-being, and, for rethinking accounting education towards a more proactive role in attracting and engaging socially aware, ethically responsible ATPs.


We consider a mathematical model for the classical Sudoku puzzle, which we call the primal problem and introduce a corresponding dual problem. Both problems are constraint satisfaction models and a duality relation between them is proved. Based on these models, we introduce a primal and a dual optimization problem and show weak and strong duality properties.


A recent NASA program to collect stratospheric dust particles using high-flying WB57 aircraft has made available many more potential candidates for the study of extraterrestrial materials. This preliminary report provides an interpretation of the types of particles returned from one flag (W7017) collected in August, 1981 using a subset of 81 allocated particles. This particular collection period is after the Mt. St. Helen's eruptions. Therefore, the flag may contain significant quantities of volcanic debris in addition to the expected terrestrial contaminants [1]. All particles were mounted on nucleopore filters and have been examined using a modified JEOL100CX analytical electron microscope. For most of the particles, X-ray energy dispersive spectra and images were obtained at 40kV on samples which have not received any conductive coating. However, in order to improve resolution (to ~30A) some images are recorded at 100kV. In addition, 16 samples have been coated with a thin layer (<50A) of Au/Pd.


While many studies have investigated effects of species composition and management on N2-fixation dynamics in simple clover-grass mixtures, there is a lack of knowledge about the performance of legumes and their N2-fixation in more species-rich grassland including non-legume forbs. This study investigated N2-fixation and total N yield in grassland mixtures including different combinations of red clover, perennial ryegrass and three deep rooted forbs: chicory, ribwort plantain and caraway, managed without and with slurry application. The percentage of clover N derived from atmosphere (%Ndfa) increased in mixtures, but was unaffected by inclusion of forbs. However, forbs affected the quantity of N2-fixation and total N yield by affecting the red clover proportion in the mixtures. Mixtures composed of grass,clover and plantain or caraway showed higher N2-fixation and N yield than with chicory included. Slurry application reduced N2-fixation due to decreasing clover contents in the sampled biomass. The study highlighted differences among forbs in their influence on legume N2-fixation and total N yield showing that forbs can be included in grasslands without negative effects on red clover performance.


A millimetric aperture Nd:glass laser system has been designed and constructed at the CEA-CESTA. Its aim is to best mimic the laser conditions that can be found in inertial confinement fusion facilities. It is therefore used to study the main phenomena that prevents these lasers to work at their maximum power: the laser induced damage of the optical components. The combination of temporal and spatial modulators provides, every minute, a 6 J, 7 mm, 351 nm homogeneous beam at the fused silica sample location. This proceeding illustrates the capacity of the facility over two experiments: the study of damage initiation and the growth of laser damage sites on fused silica, up to millimetric scales


The Caspian Sea and Persian Gulf are faced to envir onmental pollution. The (ROPME) covers eight states the Regional Organization for Protecting the Marine Env ironment that Joined force in 1978 to adopt the Kuw ait Regional Convention for Cooperation on the Protecti on of the Marine Environment from pollution, otherw ise known as the Kuwait Convention and four associated Protoc ols. The five countries bordering the Caspian Sea h ave a Convention for Protecting Caspian Sea (CEP), and re lated four Protocols. This study shows there are ma ny differences of regulation are between the two conve ntions. The main differences are pollution controls , biodiversity management and control of the hazardous waste.


Interactive White Board (IWB) has been supplied to language classrooms in a large scale in relatively short amount of time, but necessary teaching and learning models for IWB classes have not been developed to accommodate the speedy supplies of IWBs to the school system. This study aims to develop a teaching-learning model using IWB in elementary English education. To this end, needs analysis was made for 76 elementary school teachers who had used IWB in English classes via questionnaires. A meta-analysis of researches on the language input enhancement was also conducted to investigate the effect sizes of the classroom based experiments. Based on the survey result and the meta-analysis, a teaching and learning model for IWB was developed in accordance with national curriculum in its characteristics, objectives, content, method and evaluation. The current teaching and learning model was applied in IWB classroom and noted for the positive effect of using IWB as an input enhancement device. This study suggested an IWB-based teaching and learning model of English with particular reference to looking at IWB as an effective language input enhancement device which can be appropriated to the EFL circumstance in Korea. In addition, sample teaching plans were provided to enable the teachers to implement the language input enhancement techniques in classes using IWB. The study shows a possibility that IWB could be used as effective teaching-learning instrument if it's appropriately used. To make IWB an effective teaching tool, it's suggested that IWB-based English materials should be more supplied, and a community is called for teachers to develop and share the contents and activities for IWB classes.


The authors juxtapose autobiographical accounts of their personal and professional lives to examine the interplay of their personas and work in the social sciences. Chesler is an action researcher and change agent who focuses primarily on young people and their parents and on those providing them human services. Hasenfeld is an academic who focuses primarily on relations between clients and human service providers and on the systemic changes needed to improve these relations. They share domain assumptions, particularly a belief in the "good" society based on justice, social equality, and respect for diversity, are committed to improving the life chances of the oppressed and disadvantaged, and believe that empowering the clients of human service agencies is crucial to improving the effectiveness and responsiveness of such organizations.


The present invention relates to a cosmetic composition containing a banana leaf, a petal or a mixed extract thereof as an active ingredient, wherein the banana leaf, petal or a mixed extract thereof contains 0.01 to 20.0 wt% based on the total weight of the cosmetic composition. do. Banana leaf and petal extracts compared to banana fruit extracts as well as antioxidant effects, inhibiting MMP-1 production, inhibiting MMP-1 production by UV induction, enhancing collagen synthesis, inhibiting melanin production, and alleviating cytotoxicity by UV irradiation. The effect, the effect of inhibiting the expression of inflammatory cytokines by ultraviolet irradiation and the effect of improving skin elasticity can be excellently used as a functional cosmetic.


The Craftsman bungalows of designer and builder, Algernon John Elmore (1882-1961) relate in particular aesthetic and functional ways to Blackburn, Melbourne, at the time between 1910 and 1929 when it was a rural suburb. His oil-stained timber bungalows were appropriate for Blackburn. Not only did they fit harmoniously into the landscape of gums and wattles, they sat more happily on their foundations in Blackburn's heavy clay sub-soil than did solid brick houses.(1) Simple rectangular forms , striking craftsmanship in Australian timbers and many original ideas in design are the distinguishing qualities of Elmore's work.


In a method of manufacturing an illumination device, a color tone of each of a plurality of light emitting devices having different color tones is detected. In which region among a first region, a second region, a third region, a fourth region, a fifth region, and a sixth region on a chromaticity diagram the color tone of each of the plurality of light emitting devices is is determined based on the detected color tone. The chromaticity diagram has a first color tone area and a second color tone area in which the first color tone area is provided. The second color tone area is divided into the first region through the sixth region. The plurality of light emitting devices are classified into the first region through the sixth region based on the determined color tone.


This paper presents an event-triggered statistical estimation strategy and a data collection architecture for situational awareness (SA) in microgrids. An estimation agent structure based on the event-triggered Kalman filter is proposed and implemented for state estimation layer of the SA using long range wide area network (LoRAWAN) protocol. A setup has been developed which provides enormous data collection capabilities from smart meters in order to realize an adequate level of SA in microgrids. Thingsboard Internet of things (IoT) platform is used for the SA visualization with a customized dashboard. It is shown that by using the developed estimation strategy, an adequate level of SA can be achieved with a minimum installation and communication cost to have an accurate average state estimation of the microgrid.


This paper analyzed the percolation capacity and influencing factors of air foam in single homogeneous cores with different permeabilities and different gas-liquid ratios, and studied the fractional flow rates of parallel cores with different permeability ratios. The experimental results indicate that the larger the gas-liquid ratio is, the larger the flow resistance of foam system is; with the increase of permeability and volume of foam system injected, the resistance factor gets larger, and the blocking ability of foam system increases; the fluid diversion capacity is good while foam flow in heterogeneous reservoir, but with the increase of permeability ratio, the ability of foam system to divert liquid tends to decrease.


Motivation: Transcription factors of the E2F family play an important role in transcription regulation during the cell cycle. Thus, it is evident that prediction of potential binding sites for this factor in genes whose products are involved in this process is of great importance. Results: The method SITECON, based on determination of conservative context-dependent conformational and physicochemical DNA properties in short DNA fragments, allowed us to detect potential sites for binding of E2F transcription factor in promoters of several genes involved in the cell cycle regulation. It was demonstrated that potential E2F binding sites were much more abundant in promoters cell cycle genes compared with promoters of other groups of genes.


Using first-principles density functional theory calculations, two types of junction models constructed from armchair and zigzag carbon nanotube (CNT) insertion into a graphene matrix have been envisioned. It has been found that the insertion of the CNT into the graphene matrix leads to the formation of C–C covalent bonds between graphene and the CNT that distort the CNT geometry. However, the hydrogenation of the suspended carbon bonds on the graphene resumes the graphene-like structure of the pristine tube. The calculated band structure of armchair CNT insertion into graphene or hydrogenation graphene opens up a band gap and converts the metallic CNT into a semiconductor. For the zigzag CNT, the sp3 hybridization between the graphene and nanotube alters the band structure of the tube significantly, whereas saturating the dangling bonds of terminal carbon atoms of graphene makes the CNT almost keep the same character of the bands as that in the pristine tube. The synthesis of our designed hybrid structures must be increasingly driven by an interest in molecules that not only have intriguing structures but also have special functions such as hydrogen storage.


Without the aid of a computer it would be almost impossible to develop large logic networks like LSI circuits. Designing the circuit, testing the design, designing and manufacturing the masks, testing during manufacture, all these stages require so much computing work that only computer-aided design can provide the answer. At the same time it is necessary to have good software, otherwise the computing time may become impractically long, even for a fast computer. This article deals with the functional test, whosepurpose is to check whethera new designof circuit does infact perform the required logic function. If the test were to be carried out in full on a network with 64 inputs not an unusual number for anLSI circuit it would require264 experiments. Even with test equipment specially built for the purpose and checking at a rate of onceper nanosecond, the test would take more than 300 years. Such a complete test, however, would cover very many more possibilities than those of any practical interest. The programs dealt with in this article, whichare based on the structure of a network to be tested, can be used in setting up a much shorter test for checking the functional specifications. Depending on the type of network, this procedure requires only a few minutes to a few hours of computer time, while the actual test takes only a few seconds during manufacture.


Objective To investigate the effects of different doses of midazolam (M) on chronic psychological stress (CPS)-induced changes in behavior, neuropeptide release and endothelin-1(ET-1) mRNA expression in the cardiovascular center in medulla oblongata in a rat model of CPS. Methods Male SD rats weighing 150-200 g were placed in a dark box for 25 min/day×7 days (adaptation stage). Those rate which were well adapted to the environment were chosen to undergo the 2nd stage training with irregular light-electric stimulation for 25 min/day×7 days (day 8-14) (complex stress stage) . On the 15th day the animals received only light stimulation (CPS stage). The animals were divided into 3 study groups (n = 8 each): the animals received intraperitoneal (IP) normal saline (NS) 1 ml (NS-study group) or midazolam 0.75 mg·kg-1 (low dose M-study group) or 1.5 mg·kg-1 in NS 1 ml (high dose M-study group) at 10 min before CPS training. There were 2 control groups which received only dark adaptation for 7 days. On the 7th day at 10 min before dark adaptation training the animals received NS 1 ml (NS-control group) or midazolam 1.5 mg·kg-1 in NS 1 ml IP (high dose Mcontrol group) . The behavior of the rats were evaluated at the end of each stage and scored (0 = quiet, 2 = very anxious). Plasma concentrations of ACTH and corticosterone were measured (radioimmunoassay) at the end of the experiment. Paraffin sections of medulla oblongata were used to determine ET-1 mRNA expression (in situ hybridization histochemistry) . Results The rats in NS-study group behaved more anxiously and had higher scores than those in high dose M-study group and the 2 control groups (P 0.05). The number of exploratory behavior measured after stress was significantly larger in the two control groups than in the NS-study group. The plasma ACTH and conticosterone concentrations were significantly higher in NS-study group than in other 4 groups. The ET-1 mRNA expression in the cardiovascular center was significantly higher in the 2 midazolam-study groups than in NS-study group. Conclusion Midazolam can decrease the CPS-induced changes in behavior and neuroendocrine function and inhibit to some extent the decrease in ET-1 mRNA expression induced by CPS.


Expressions are obtained for the longitudinal current density in a line consisting of two parallel strip conductors of equal width on the surface of a semi-infinite ferrite magnetic along the conductors. The calculated current distributions, taking into account the effect of the fields arising in the magnetic ferrite when the strip conductors are excited by equal currents in the same and opposite directions, are given. The Fourier transforms of these current densities are used to calculate the radiation resistances of the double-strip line on the surface of a ferrite substrate of finite thickness magnetized along the conductors. The results of calculations of the radiation resistances when the line is excited by currents in the same and opposite directions are given


Current scoring systems for dental caries do not consider the dynamic nature of the disease. The aims of the present study were to describe a new set of clinical caries diagnostic criteria which differentiate between active and inactive caries lesions at both the cavitated and non–cavitated levels and to evaluate the reliability of this criteria system in a population with high caries experience. Ten diagnostic codes were defined: 0 = sound; 1 = active (intact); 2 = active (surface discontinuity); 3 = active (cavity); 4 = inactive (intact); 5 = inactive (surface discontinuity); 6 = inactive (cavity); 7 = filling; 8 = filling with active caries; 9 = filling with inactive caries. Distinction between active and inactive caries lesions was made on the basis of a combination of visual and tactile criteria. The inter– and intra–examiner reliability was assessed through repeated examinations of 50 children by 2 recorders over a period of 3 years. The percentage agreement of caries diagnoses varied between 94.2 and 96.2%. The kappa values ranged between 0.74 and 0.85 for intra–examiner examinations and between 0.78 and 0.80 for inter–examiner examinations; 81.6% of all misclassifications involved non–cavitated caries lesions. Disagreement between sound surfaces and non–cavitated active or non–cavitated inactive lesions (31.3 and 31.2%, respectively) was more common than disagreement between non–cavitated active and non–cavitated inactive lesions (10.6%). The probability of reconfirming a sound, non–cavitated active or non–cavitated inactive caries lesion – given that the surface was diagnosed as either sound, non–cavitated active or non–cavitated inactive at the first examination – was 98.0, 68.7 and 72.5%, respectively. The results show that the use of a new set of clinical caries diagnostic criteria based on activity assessment can be performed with a high reliability, even when non–cavitated diagnoses are included in the criteria system.


The ship Kelvin-wake models on two-dimensional (2-D) linear and nonlinear sea surfaces are combined with the second-order small-slope approximation method (SSA-II) to comparatively study the corresponding electromagnetic (EM) scattering characteristics. The nonlinear sea-surface models include the Choppy Wave Model (CWM) and the second-order Creamer model (Creamer (2)). Considering the limitations of using the ideal plane EM wave incident upon a rough sea surface of the limited size, the modifled tapered wave is utilized as the incident wave to derive the scattering waves. Due to the fact that the nonlinear efiects of Creamer (2) surfaces is obviously stronger than those of CWM surfaces, the bistatic normalized radar cross section (NRCS) calculated from Creamer (2) surfaces is signiflcantly greater than that of its linear and CWM surfaces for scattering angles departing from the specular direction, and the backscattering coe-cients from Creamer (2) surfaces are also the greatest except within quasi-specular (near vertical incidence) region. Moreover, for the linear and nonlinear sea surfaces, the in∞uences of difierent wind speeds and directions on scattering characteristics are also calculated and analyzed in detail. However, taking the ship Kelvin wakes into account, the corresponding scattering features are obviously distinct from those of the single linear and nonlinear sea surfaces. This helps to provide a basis to extract the related ship information through the scattering characteristics of ship Kelvin wakes. Also it shows that the small-slope approximation method is a very efiective analysis method to deal with the EM scattering from the rough sea surface.


A detailed description is given of the way in which ground state properties of solids may be obtained in the framework of the density-functional scheme using non-local norm-conserving pseudopotentials and plane-wave expansions. Explicit expressions for matrix elements of the pseudopotential are given and a useful expression is derived relating Fourier components of the total valence charge density through space group symmetry. Silicon and diamond are treated as illustrative examples. The computational details and results are presented in such a way that they may serve as a reference.


The railway transport has a significant increase potential of the transportation process energy efficiency at the realization of a variety of events for energy saving. This is due to the possibility of the efficiency's increase of the regenerative braking use on the electric rolling stock by using the perspective energy storage systems. In this article the authors provide simulation modeling results of the interaction of the electric rolling stock and the electric traction system, which were received with the help of the proposed calculation's order. The given results allow performing the analysis of the variety factors' influence, such as regenerative braking, speed of movement, train's weight on the overall energy efficiency of the transportation process, as well as in the condition of the energy storage units' use. The presented model was developed in the matrix system Matlab and was verified by the operational date about the electric rolling stock operation.


Taking the application of intelligent recommendation in the military field as the research object, an intelligence recommendation model based on UML is established. Firstly, the characteristics and modeling process of UML are briefly introduced; Then, the working principle of the intelligent recommendation system for military intelligence and the workflow of recommending intelligence are explained; Finally, using UML tools to establish visual models of the system and its information flow from the perspectives of functional requirements, requirements analysis, system behavior, such as use case diagrams, class diagrams, state diagrams, activity diagrams, sequence diagrams and collaboration diagrams, which builds a bridge of undifferentiated communication between designers, developers, and intelligence users, and provides a scientific and feasible method for the design, construction and optimization of intelligent recommendation system.


A new application of magnetic separation suitable for micron-scale solid–solid separation is designed and demonstrated on a pilot plant scale synthesis of amoxicillin trihydrate.


An approach for reliability assessment of the ultimate strength of a ship hull structure in the presence of corrosion is developed. Corrosion growth is modeled as a time dependent random function that decreases the thickness of ship hull structural members with time. The second order reliability method (SORM) is used to calculate instantaneous reliability of the primary hull structure. The methodology for computing the time dependent reliability of a corroding ship structure is developed. Sensitivity of the time dependent reliability of the structure to statistical and probabilistic description of the corrosion growth parameters is investigated. An example problem involving a corroding tanker structure is used for demonstration.


The author reviews his five years experience with a psychiatric unit in a general hospital. He reviews the American Literature noting such units are thought to be important. There has been no discussion of the community roles of such units. From his experience, he recommends such units play a limited but specific function in the medical and mental health delivery system.


Patient experience is an important component of high‐quality care and is linked to improved clinical outcomes across a range of different conditions. Patient‐reported experience measures (PREMs) are psychometrically validated instruments designed to identify where strengths and vulnerabilities in care exist. Currently, there is no validated instrument available to measure patient experience among people aged over 65 years attending the emergency department (ED).


This paper reveals a missing thread in the global historiography of architectural theory by scrutinizing the relationship between political ideology and architectural discourse in Mao's China (1949–76). Several critical moments in this era, during which new theories or concepts emerged, deserve close study: 1) the National Style in 1954; 2) the official design principle, 'appropriateness, economy, and if possible, beauty' in 1955; 3) the Socialist New Style in 1959; 4) the Design Revolution in 1964; and 5) the 'new architecture' in 1973. The political context and the role of state ideology are discussed with regard to the relevant texts, buildings, architects and design institutes. Discussion focuses on the mode of theoretical production in the Mao era, which is summarized as a relation between 'container' and 'content'. The broad and abstract theories of the time are conceptual containers that failed to define specific contents. Architectural autonomy continued to exist in the form of knowledge accumulation, especially the absorption of modernism, even though state ideology and political movements dominated architectural discourse.


‐ Over twenty‐five years after the Serrano v. Priest (1971) decision by the California Supreme Court sparked intense debate over school finance equity, the topic remains at the forefront of the education reform debate in many states. Over the past two decades, a number of states have faced lawsuits over the equity of their school finance system, and several states have been forced to make changes. In the last several years, a new round of court cases has challenged traditional equity standards and solutions implemented in response to past court orders. Several of the recent challenges, most notable in Kentucky and Michigan, have involved reform of the whole school finance system. Accompanying the continued debate over school finance equity has been intense interest in reforming the organization and performance of public schools and renewed opposition to local property tax financing of education. After the 1983 publication by the national commission of Excellence in Education of A Nation at Risk, with its scathing critique of American education, "education reform" has become the rallying cry for major structural changes in public schools. Reforms have ranged from the establishment of minimum competency standards and mandatory testing (Fuhrman, Elmore, and Massel, 1993) to the development of new performance incentives for teachers, school, and school While states have debated how to improve public school performance, the property tax ‐ the heart of local school finance ‐ has come under renewed attack. Recent proposals to reduce the role of the local property tax in financing schools have been passed in five states (Michigan, Oregon, Wisconsin, Nebraska, and Vermont) and have been considered in several more (Gold, 1994a; Reschovksy, 1994). Despite the fact that state education finance systems have been under challenge on a number of fronts, public finance and education research continues to be segmented into separate


In this paper, I argue that despite the general belief to the contrary, there is a great deal of continuity in the history of the colonial and post-colonial practice of citizenship in the Indian Ocean region. This debate is usually described from the perspective of the state and its representatives. Indeed, more often than not, the position of the migrants themselves is not discussed. This paper aims to fill this gap. In the case of the South Asians in East Africa, I will demonstrate that migrants were able to negotiate their own space for identity formation and accepting and changing formal citizenship options. Indeed, they were also able to negotiate with colonial officials and, after the 1960s, Britain, Canada, India and even the United Nations about defending their rights as citizens or agreeing new regulations for international migration and citizenship. The debate on citizenship and belonging has become the centre of academic and public debate since the 1990s in Europe and the USA. However, historical cases in colonial contexts might shed some light on long-term continuity in such discussions.


The presence of mobile devices makes human work easily as in terms of helping to organize schedules of routine activities. During this time the Seventh Day Adventist Church in Indonesia has an annual Bible reading schedule for all members, but it is still created and distributed in paper form which it is easily damage and even lost. This study aims to develop a mobile application that will be used by the leaders of the Seventh Day Adventist Church in arranging annual Bible reading activities that are regularly followed by the members of the church and to view the progress reports of the Bible reading activities. Waterfall model has been used as a methodology in this research that is followed by the following steps: (1) Analysis, (2) Design, (3) Implementation, (4) Testing, (5) Maintenance. Through this research, a mobile application was developed and it is used by the Adventist church leaders to create and distribute the daily Bible reading schedules for personal and for families. Through this application also the leaders can receive reports of Bible reading activities progress. In addition, the results of this study facilitate Adventist church members in completing their annual Bible reading activities. This application is still limited to text view and for the future, it is expected to be developed in audio and video formats.


Catastrophic forgetting is a major problem that affects neural networks during progressive learning. In it, the previously learned representation vanishes as the network learns new information. The extreme learning machine is one of the variants of the neural network. It is used in many domains due to fast training and good generalization ability. However, like other neural networks, it suffers from catastrophic forgetting and negative forward and backward transfer during the progression of neurons in incremental learning. The study hypothesizes that it is due to overlapping in hidden neurons and output weights. The global representation by an activation function further supports this hypothesis. To address this, the study proposes a neuron clustering approach to mitigate it in an adaptive class incremental extreme learning machine. The neuron clustering method activates k nearest neurons during learning and testing. It helps to partition the network to select overlapping subnetwork. Experimental results on four food datasets show that the proposed approach reduces negative forward and backward transfer when neurons are added incrementally during progressive learning.


A two-stage supervisory control system is designed based on Siemens PLC(Programmable Logic Controller) according to the control requirement of ice-storage central air conditioning in this paper.The fieldwork station is composed of a PLC and a touching screen,which acts as a local platform of SCADA(Supervisory Control and Data Acquisition);the managing-work station is made up of an industry computer and a printer,serving as a main HMI(Human Machine Interface) which can print data and control the fieldwork station remotely in addition to all functions of the field work station.Results show that the designed supervisory control system can monitor and control the states of ice-storage central air conditioning timely and increase the cooling capacity and cooling efficiency effectively.


Based on a project example,this paper shows the design of the composite piled foundation and the calculation methods of the bearing capacity of the foundation with tree root as the master pile and the cement-soil pile as auxiliary pile.And then through the economic analysis the paper shows that the composite piled foundation to some extent has better eco-nomic efficiency and applicability.Finallyt,hrough the example analysis the paper draws some constructive conclusionst,hus providing reference for engineering designers.


Gold nanoparticles (GNPs) are proven effective heavy-atom radiosensitizers to produce imaging contrast and dose enhancement in radiotherapy. To understand the physical and biological effect of adding GNPs to the tumour cells, Monte Carlo simulation based on particle tracking and transport, is employed to predict the dosimetry in the cellular and DNA scale. In this review, we first explore the recent advances in Monte Carlo simulation on GNP radiosensitisation. The development of particle tracking algorithm for very low energy electron in the simulation is discussed, followed by some results regarding the prediction of dose enhancement (microscopic and macroscopic). We then review different Monte Carlo cell models with GNPs in the simulation, the biological effect resulting from DNA damage, and the effects of increasing imaging contrast in the tumour cell due to photoelectric enhancement. Moreover, we explain and look at different studies and results on GNP-enhanced radiotherapy using gamma rays (brachytherapy), megavoltage photon, kilovoltage photon, electron and proton beams.


Infantile spasms(IS) is an age-specific epileptic syndrome,which has some features such as earlier age of onset,specific form of convulsion,progressive intelligence regression,and hypsarrhythmia in electroencephalogram(EEG).The etiologies of infantile spasms are complex and diverse.The pathogenesis is unclear till now.Although the treatment methods had improved,but still difficult to cure,and often left behind intelligent defects.


Are there ways in whi ch American mission agencies can improve their response to the need for continued ministries in education by the churches in Asia, Africa and Latin America? An investigation of this question was conducted by the writer during the first four months of 1968, aided by a small research committee composed of Eugene L. Smith, Robert Lodwick, Paul R. Gregory, Samuel R. Smith, Hubert C. Noble and Howard Schomer, under authorization by the Specialized Ministries Department, Divi sion of Overseas Ministries (DOM) of the National Council of Churches.


Several models of the evolution of religion claim that ritual creates "religion" and gives it a positive evolutionary role. Robert Bellah suggests that the evolutionary roots of ritual lay in the play of animals. For Homo sapiens, Bellah argues, rituals generate a world of experience different from the world of everyday life, and that different world of experience is the foundation of later religious developments. Robin Dunbar points to trance dancing as the original religious behavior. Trance dancing both alters ordinary consciousness and generates trance experiences that will give rise to religious concepts and also, through the production of endorphins, bonds people into tight-knit social groups whose social bonding gives them a survival advantage. The role of ritual in social bonding has been well established through the research on the production of endorphins by synchronized activity and the role of endorphins in social bonding. The role of ritual in generating religious experience has been much less developed. Drawing on the extensive research on the ways in which bodily activity can impact and transform our sensory and cognitive processes, and the ways in which sensory and cognitive processes are neurologically connected with somatic processes, this article will propose one neuropsychological model of how ritual activity might give rise to religion. Starting from bodily activity means that here religion will be understood more as a set of practices and less as a set of beliefs. Theological implications of this model will be discussed.


The chemiluminescence of three epoxy networks based on diglycidyl ether of biphenol A (DGEBA) crosslinked by respectively the phthalic anhydride (PA), hexahydrophthalic anhydride (HHPA), and methyl tetrahydrophthalic anhydride (MTHPA), was studied in the 180–240°C temperature range. Isothermal stationary and nonstationary (perturbed) experiments revealed that the behavior depends sharply on the anhydride structure. The higher emissivity of cycloaliphatic systems (MTHPA and HHPA) is explained in terms of hydrogen abstractibility on the hardener's moiety. The main difference between MTHPA and HHPA (intensity initially decreases for the former, increases for the latter) is explained by the consumption of the MTHPA double bonds in oxidative crosslinking processes. The results of perturbed experiments were essentially attributed to changes of alkyl radical concentration during the exposure under nitrogen. These changes can be modelled by a simple kinetic model taking into account the observed differences between the systems under study. © 1993 John Wiley & Sons, Inc.


The Arctic region [1] is changing and has throughout the past decade gained growing political attention, notably due to the increasingly visible consequences of climate change and the changing geopolitical dynamics of the area. The USGS's (US Geological Survey) estimate that the Arctic region is likely to hold around 25% of the world's undiscovered hydrocarbon reserves, has sparked a debate about new economic opportunities in the region (Wilson Rowe 2013: 72-73).


Recently, we reported rifabutin hyperactivity against Acinetobacter baumannii. We sought to characterize potential interactions between rifabutin and colistin, the last-resort drug for carbapenem-resistant infections. Rifabutin and colistin were synergistic in vitro and in vivo, and low-dose colistin significantly suppressed emergence of resistance to rifabutin. Thus, this combination is a promising therapeutic option for highly resistant A. baumannii infections. ABSTRACT Recently, we reported rifabutin hyperactivity against Acinetobacter baumannii. We sought to characterize potential interactions between rifabutin and colistin, the last-resort drug for carbapenem-resistant infections. Rifabutin and colistin were synergistic in vitro and in vivo, and low-dose colistin significantly suppressed emergence of resistance to rifabutin. Thus, this combination is a promising therapeutic option for highly resistant A. baumannii infections.


In the field of fault diagnosis of power transformers, the main disadvantage of the back propagation algorithm of wavelet neural network commonly used lies in the optimization procedure getting easily stacked into the minimal value locally and strict requirement on the initial value, which would make fault diagnosis difficult to some extent. This paper presents a fault diagnostic method based on the genetic algorithm evolving wavelet neural network. The selection of network structure and parameters is carried out by use of the real value encoding genetic algorithm instead of artificial setting. Throughout the process, compromise is satisfactorily reached among the network complexity, the convergence and the generalization ability. The results of numerical examples show that the algorithm proposed has good classifying capability of both single-fault and multiple-fault samples as well as high accuracy of fault diagnosis.


The study envisaged assessing the general combining ability of the parents and specific combining ability of the hybrids, using line x tester mating design. Twenty four hybrids (derived from mating four testers with six lines in L x T design) along with their parents and checks ((SSG 59-3 and MFSH 4)) were evaluated at two locations with two date of sowing (Early and late sowing) during the kharif season of 2015-16. Data on five randomly taken plants from each genotype in each replication were recorded on different quantitative characters at first cut (55 days after sowing) and second cut (45 days after first cut). The ratio of σ 2 GCA/σ 2 SCA was less than unity for all the characters indicating preponderance of non-additive gene action (dominance and epistasis). Among female parents 9A and 14A was the best combiner for green fodder yield and 14A for dry fodder yield in more than two different environments. Among male parents, HJ 513 and G 46 were found to be the best general combiner for green fodder yield and dry fodder yield. The cross combination of 465A × HJ 513 and 9A × IS 2389 exhibited high and positive sca effects for green fodder yield as well as for dry fodder yield. This suggests the usefulness of heterosis breeding or any breeding plan which makes use of specific combining ability effects for improvement in these traits.


Of all the influential factors,social mechanism is of most importance and decisive to the occupational morality of the young teachers in colleges and universities.This paper has provided a comprehensive analysis.With particular emphasis on these major drawbacks that affect the occupational morality of young teachers,this paper also adheres to principles that combine the ideal requirement of teachers' occupational morality with the(youngs) concern on their individual development.There is also an exploration on building up social mechanism.


Objective] To assess the effects of diet intervention on dietary behavior of patients with metabolic syndrome in community. [Methods] 132 patients with metabolic syndrome were randomly selected. Among then 66 patients received 3 months dietary intervention by the methods of food-exchange, the other 66 patients were used as control. [Results] The total energy, the quantity of carbohydrate and fat that intervened group took in per day, and the proportion of calorie from fat to the total energy of the intervened group decreased significantly after diet intervention, and were significantly lower than those of the control group. [Conclusion] The diet intervention carried out to patients with metabolic syndrome in community can improve their diet behavior effectively.


Paper and ink have been continually evolving since their invention. Conventional printing quality and cost is constantly improving, yet only few examples of commercial embedded electronics on paper exist. This is due to the fact that inks with optical and electronic properties do not suit conventional paper and are still challenging to print reliably. In this project, we aim to develop a new generic mass media "next generation" paper. We present the challenges and progress on book augmentation, using printing technologies such as screen printing and roll-to-roll fabrication. This first step aims to create an augmented book prototype via hybrid integration of optical sensors in its pages and by embedding energyefficient control and communication electronics in the cover. The system senses user interaction and, through wireless connectivity, presents the user with relevant, updated digital content on an adjunct device. The proposed fabrication sequence has been developed with close attention to the requirements of industrial scale-up.


Abstract Byproducts/wastes of iron- and steelmaking processes and steel scrap are the main sources of iron units recycled in the steel plants. Direct recycling of the iron oxide wastes (dusts and sludge) in the blast furnace (BF) is however hampered by its chemistry (>0·1%Zn in the charge). Vaporisation, condensation, oxidation and circulation of zinc may collectively lead to the accumulation in the furnace. Very fine particles are deposited on other particles that have high surface areas which diminish BF refractory life and impair the quality of high quality pig iron produced. For effective continuous recycling of iron units, it is necessary to identify their sources, determine their composition and evolve device and appropriate technology for the treatment of zinc bearing units. The present paper analyses the process of zinc accumulation in the BF and derives an algebraic model to determine the extent of the accumulation. On the basis of analysis of zinc base formation, its recirculation in the furnace and other related productive units, a homograph (alignment chart) of zinc accumulation is designed. The paper also outlines the feasible processes of zinc removal from the close-looped system (sinter plant–BF–sinter plant).


An apparatus and method for controlling a shape memory alloy phase transformation temperature. The apparatus comprises a primary wire made of a shape memory alloy. A primary wire defining first and second ends, the first end attached to a fixed structure, the second end portion can be displaced. Activation source thermally coupled to the wire, and is operable to selectively cause the primary wire during a cycle phase reversibly transform from martensite to austenite phase. Loading element operatively connected to the primary wire, and configured to, when the ambient temperature is at or above the critical temperature to selectively increase the tensile load on the primary wire, thereby increasing the phase transition temperature of the main wire.


This note introduces the special issue of the System Dynamics Review celebrating the 50th anniversary of the founding of the field. Copyright © 2007 John Wiley & Sons, Ltd.


To define a metric for the separability between water and olefinic fat peaks that defines a threshold beyond which the extraction of the olefinic fat peak from vertebral bone marrow short‐echo time‐stimulated echo acquisition mode MRS at 3T is feasible when using a constrained peak fitting based on the triglyceride fat model.