a During the past five years, the filament wound DuPont PRD-66 filter element has undergone considerable development to improve the structural integrity of the outer membrane, and to produce a nearly complete barrier vs. bulk filter element. Additional improvements have included the incorporation of a strengthened, integral flange and reinforced end cap are% and achievement of acceptable gas flow resistance through the as-manufactured filter body. DuPont PRD-66 filters were installed and operated in the Westinghouse Advanced Particulate Filtration unit at the American Electric Power pressurized fluidized-bed combustion test facility in Brillian~ OH, in 1994 and 1995, and at the Foster Wheeler pressurized circulating fluidized-bed combustion test facility in Karhula, Finland, in 1997. Both field test operations, as well as bench-scale qualification testing conducted in Westinghouse's pressurized fluidized-bed combustion simulator test facility in Pittsburgh, PA, have identified several life limiting issues that warrant continued development prior to commercial use of the filament wound PRD-66 candle. Additional efforts remain to be focused on the development and production of a dual membrane, barrier candle filteu further strengthening of the flange; and incorporation of a chip resistant outer surface. Thk report provides a summary of the efforts conducted at Westinghouse which have supported the development manufacture, and field test operation of the DuPont PRD-66 candle filters. Introduction Two tasks were conducted by Westinghouse in support of DuPont's DOE/F13TC program entitled "Advanced Hot Gas Filter Development" (Contract No. DE-AC2i-94MC3 1214A). These included: Task 2Test Plan Deftition Task 3Development, Qualification, and Testing of Hot Gas Filters. I


A three-dimensional (3-D) method of analysis is presented for determining the free vibration frequencies of a shallow spherical dome. Unlike conventional shell theories, which are mathematically two-dimensional (2-D), the present method is based upon the 3-D dynamic equations of elasticity. Displacement components u φ , u θ , and uz in the meridional, circumferential, and normal directions, respectively, are taken to be periodic in θ and in time, and the algebraic polynomials in the φ and z directions. Potential and kinetic energies of the shallow spherical domes are formulated, and the Ritz method is used to solve the eigenvalue problem, thus yielding upper bound values of the frequencies by minimizing the frequencies. As the degree of the polynomials is increased, frequencies converge to the exact values. Convergence to four-digit exactitude is demonstrated. Natural frequencies are presented for different boundary conditions. The frequencies from the present 3-D method are compared with those from a 2-D exact method, a 2-D thick shell theory, and a 3-D finite element method.


This work is based on research supported by the South African Research Chairs Initiative of the Department of Science and Technology and National Research Foundation (DST/NRF) of South Africa.


Managing dangerous wildlife is often problematic. Complex community perceptions, interagency debates over responsibilities, declining resources, threats of litigation, and other issues may fully test the technical skills and resolve of management agencies (Berwick and Saharia 1995). When such situations occur in suburban environments, all of these issues may become even more acute, especially when public perceptions are manipulated and exacerbated by sensationalist media coverage (Decker and Enck 1996). Every year in towns and cities throughout Australia, breeding Australian magpies (Gymnorhina tibicen) attack and often injure large numbers of people passing near the birds' nest trees (Jones 1996). Although wildlife agencies in every state devote enormous amounts of time and resources to


We propose a variation of online paging in two-level memory systems where pages in the fast cache get modified and therefore have to be explicitly written back to the slow memory upon evictions. For increased performance, up to α arbitrary pages can be moved from the cache to the slow memory within a single joint eviction, whereas fetching pages from the slow memory is still performed on a one-by-one basis. The main objective in this new α-paging scenario is to bound the number of evictions. After providing experimental evidence that α-paging can improve the performance of flash-memory devices in the context of translation layers we turn to the theoretical connections between α-paging and standard paging. We give lower bounds for deterministic and randomized α-paging algorithms. For deterministic algorithms, we show that an adaptation of LRU is strongly competitive, while for the randomized case we show that by adapting the classical Mark algorithm we get an algorithm with a competitive ratio larger than the lower bound by a multiplicative factor of approximately 1.7.


We review the emerging field of optomechanics, where the radiation pressure of light circulating inside an optical cavity is employed to cool, manipulate and read out micro- and nanomechanical oscillators. These systems display a rich classical nonlinear dynamics and can be used for sensitive detection. Once they are successfully cooled into the quantum ground state, they promise fundamental tests of quantum mechanics in a new regime.


TH E most appropriate method of selecting a sample for the measurement of consumer preference is a subject of much discussion among research practitioners. Several different points of view are current, but, fortunately, the differences of opinions represent variations in degree of emphasis rather than lack of agreement on points of fundamental theory. The purpose of this paper is to point up the issues involved in selecting a sampling method, and to indicate, if possible, a general method of determining which type of sample shall be used for particular cases. In doing so, particular attention will be given to nonproportional stratified samples-a type not widely used by practitioners although long recognized in theory.


Internet of Things analytics engines are complex to use and often optimized for a single domain or limited to proprietary data. A prototype system shows that existing Web analytics technologies can successfully be repurposed for IoT applications including sensor monitoring and user engagement tracking.


RA Wood, SH Sicherer, BP Vickery; for the Consortium of Food Allergy Research. J Allergy Clin Immunol. 2013;131(3):805–812

Previous studies on the natural history of milk allergy have been limited in duration and in geographic area. Through this multisite, longitudinal study, the authors provide a natural history of milk allergy and identify means for early prediction of likelihood of resolution.

Children aged 3 to 15 months were recruited from 5 food allergy referral centers, using the following inclusion criteria: history of immediate allergic reaction to cow's milk or egg with positive skin-prick test (SPT) to the inciting food; or moderate-to-severe atopic dermatitis (AD) with positive SPT to …


Global classical solutions near the relativistic Maxwellian are constructed for the relativistic Boltzmann equation in both a periodic box and the whole space. For both cases, we are able to get the non‐negativity of the global solution under less restriction than in (Publ. Res. Inst. Math. Sci. 1993; 29:301–347) on the scattering kernel. Copyright © 2006 John Wiley & Sons, Ltd.


For chest pain patients with normal electrocardiogram and initial troponin results, adverse events are rare but serious. Some emergency physicians,


As many technological innovations, the Unmanned Aerial Vehicles (UAV) were created for military purposes. However, these aircrafts are now a reality accessible for common civilians and are used to explore new possibilities in areas like cinema, photography or surveillance. The technology easily reached other application fields and turned into a new sports category as well, supported by many drone racing competitions that happen around the world. There are many alternatives to control a quadcopter, but the most accurate relies on a robust and heavy handheld remote controller that requires dexterity to be a good pilot. This limits the control of the UAV to users comfortable with this kind of interaction, discarding people with reduced fine motor skills, hand malformations or elders with low learning capacity from the possibility of piloting a quadcopter and participate in competition events. An alternative to these remote controllers should be developed to overpass the mentioned disadvantages. The solution proposed in this paper is an intuitive and accurate control system made of two small and lightweight wearable devices capable of detecting patterns based on motion events. These patterns are then sent to a mobile application responsible for controlling the drone. Wearing the described devices like a high-tech glove, the users can pilot the UAV through simple and intuitive upper limb movements, being the changes in the orientation of each device over time identified as a specific pattern. This solution presents a new approach to the control of UAV that improves the ease of piloting them and decreases the time that is required to learn how to handle them.


Gastrointestinal emergencies constitute a huge clinical and economic burden in various emergency units all round the world. They constitute 12% of all the emergency visits and are associated with a mortality of over 10%. They are a result of either underlying significant life threatening inflammation, infection, ischemia, vascular lesions, obstruction or perforation of the GI tract. They often present in the emergency setting with superadded septicaemia / shock / organ failure. Gastrointestinal (GI) emergencies like other emergencies require time critical interventions to minimize morbidity and mortality. In contrast to other emergencies, it requires multidisciplinary approach involving gastroenterologists, radiologists, surgeons and critical care specialists. They also result in higher hospitalization rates compared to those presenting with non-GI problems (21.6% vs 14%). In contrast to cardiac and neurological emergencies, managing most GI emergencies require relatively low cost interventions which are life saving. Cardiologists and neurologists have gone a long way in improving the structure and processes in managing the two of their common life threatening emergencies namely myocardial infarction and stroke. They have also strived to improve public awareness of these conditions resulting in making them partners in the process of emergency care delivery. Gastroenterologists still have to take these issues head on. Quality improvement studies are severely lacking in the field of gastrointestinal emergencies and usually pertain to only managing endoscopy services in patients with GI bleeding.


This study investigated the effects of the mixed solid fermentation of honeysuckle cereal mixed flour with lactic acid bacteria and yeast on dough characteristics and bread quality. Honeysuckle powder and whole wheat flour were mixed to make reconstituted cereal flour, and yeast and Lactobacillus plantarum were implanted and mixed to make dough for fermentation. The dynamic rheological properties of the dough were determined, and the properties of the reconstituted cereal flour bread were determined, including the texture characteristics and color; then, the sensory evaluation and antioxidant capacity of the bread were determined. The storage modulus (G′) and loss modulus (G″) of the dough increased gradually with the increase in the honeysuckle powder content, and the loss tangent value, tanδ (G″/G′), was less than 1.0. The loss tangent value of the dough had no significant change (p > 0.05) with the increase in honeysuckle powder content; the L* value of the bread decreased from 88.50 to 76.00, the a* value increased from −1.87 to 0.79, and the b* value decreased from 21.04 to 13.68 with the increase in the amount of honeysuckle powder. When the honeysuckle powder addition was 4%, the reconstituted cereal bread was bright yellow and gave off a hint of bean and wheat flavor and had the best taste and quality. The hardness, chewiness, and the recovery of the bread decreased when the content of the honeysuckle powder was in the range of 0~4%, but the elasticity and the antioxidant and antiaging activity of the bread increased significantly (p > 0.05). It was determined that the best content of honeysuckle powder was 4%. The mixed microbial fermentation of honeysuckle cereal mixed flour can improve the quality and enhance the nutritional value of bread.


The concentrations of peroxide in uranyl sulfate solutions at incipient precipitation of uranium peroxide were determined at 79 to 114 ts C. The results of the experimental observations were used to calculate a self- consistent set of numerical parameters that are related to the equilibrium of hydrogen peroxide, uranyl ions, and hydrogen ions. The observed concertrations of peroxide at saturation were found to follow the relation: P/sub (sa//sub t/) = STA1.0 + 36O(H/sup +/)/sup 2//(UC/sub 2/ i/sup ++/)! x 10/sub -4/ in terms of the stoichiometric acid and uranyl ion>i concentrations investigated.


List of plates Notes on contributors Preface Abbreviations 1. Introduction Charles Martindale 2. Horace at home and abroad: Wyatt and sixteenth-century Horatianism Colin Burrow 3. The best master of virtue and wisdom: the Horace of Ben Jonson and his heirs Joanna Martindale 4. Marvell and Horace: colour and translucency A. D. Nuttall 5. Cowley's Horatian mice David Hopkins 6. Figures of Horace in Dryden's literary criticism Paul Hammond 7. Horace's Ode 3.29: Dryden's 'Masterpiece in English' Stuart Gillespie 8. Pope and Horace Robin Sowerby 9. Good humour and the Agelasts: Horace, Pope and Gray Felicity Rosslyn 10. Horace and the nineteenth century Norman Vance 11. Horace's Kipling Stephen Medcalf 12. Some aspects of Horace in the twentieth century Charles Tomlinson 13. Deniable evidence: translating Horace C. H. Sisson 14. Postscript: images of Horace in twentieth-century scholarship Don Fowler Notes Bibliography Plates Index.


Global warming is one of the environmental reasons for the adoption of the electric vehicle (VE). This technology is very welcome by society but carries great challenges to electricity distribution networks. VEs will need to be recharged and extra amount power demand could lead to occurrence of several operational problems in the distribution system. An optimization model is required in a concept called vehicle-to-grid or V2G. The main issue of this optimization model lies in the power flow equation which are non-linear and non-convex making the problem hard to be solved for large scale integration of VEs. Therefore, we use a semidefinite approximation of the power flow and evaluate the model in different scenarios. Electric vehicles are coordinated by aggragators that are spatially distributed along a primary feeder. Each aggregator collects a group of EVs of different rate of charger. The objective function is to minimize power loss and maximize state-of-charge (SOC) or owner satisfaction. Several scenarios were taken into account: first, a base case where we compare the proposed model with others models propose in the literature, next we analyze the integration of EVs for 25%, 50%,75% and 100% of the total power demand of the system, with of aim of evaluating the control variables and load loadability on the IEEE 37 nodes and IEEE 29 nodes test feeders.


In the background of the internet age, industrial design has been the important driving force of Chinese economic transformation and development. On the basis of meeting the functional requirements , product design is supposed to pay more attention to people-oriented and environment-friendly. Products which are pleasant, livable and sustainable will be more competitive in the market, but also be more representative of the future development trend. Using the rise of the ecological design concept in recent years to guide the product design meets the background of times,study on the relevant design theory and design methods meets the needs of the times. Based on the background of the Internet and the influence of ecological concept on the design of PI (product identify), this paper analyzes and compares the existing PI design content and discusses a new PI design concept which is more in line with the current design concept and future development trend.


This paper is devoted to economical substantiation of organization of touristic routes, and relevant activities of tour operators in terms of profitability. Currently, rational use of local natural and man-made recreational resources, as well as successful business activity in tourism can be reached considerably due to effectively-organized touristic routes. The organization of such tours seems efficient for tour operators which may gain more benefit from collective forms of the excursions. However, it is important for a company organizing touristic route to function more effectively and gain real profit with considering primary costs, tax paying and other conditions in tourism market. In this connection, ways of measuring relevant expenditure are investigated in this paper. The study is carried out on the example of Sheki-Zagatala, the advanced tourism region of Azerbaijan Republic in order to substantiate profitability of organizing touristic route in practice. The research objective of the paper is to find more effective and profitable way of organizing touristic routes and evaluate relevant profitability limit for tour operators. For this purpose, prior measuring, planned measuring, individual calculation, and rent per tour were used as applicable methods. The results of the research show that rent per tour should be based as an effective way of evaluation of profitability, where main and variable expenditures, as well as incomes of a company must be taken into consideration. Meanwhile, the existing and recommended local routes in Sheki- -Zagatala are shown and offered, with the analysis of the local natural and man-made recreational resources. Recommendations on improvement of organization of tours are offered as well.


The reliability growth model is very available tool using during the development phase of electronic devices, of software products. In this paper we review reliability growth models a brief survey of hardware reliability growth models, of software reliability growth models.


[Objective]To observe the changes of glandular inclusion body in lymph nodes of gynecologic malignant tumors,so as to discuss differential diagnosis and the significance of clinical pathology.[Methods]Glandular inclusion body in lymph nodes of pelvic cavity and abdominal cavity from 1 603 cases of radical operation of gynecologic malignant tumor were observed to learn their distribution,quantity and changes of morphology.[Results]The incidence of lymph nodes involved were obturator foramen lymph nodes,internal and external iliac lymph nodes,and abdominal aorta para-lymph nodes in sequence.There was one lymph node involved in most cases.The glandular inclusion bodies were usually in tunica and subcapsular sinus.The number of focus of infection was generally one in every case and the number of gland was often one in every focus.The arrangement of glands was very different such as anomalistic circle and ellipse,shape of cucurbit,petal,capsula or cluster.The glandular epithelium could be any type of Mullerian epithelium,majority of them were similar to fallopian tubal epithelium.Many glandular epithelium appeared as single layer,no heteromorphism and nuclear division.[Conclusions]Lesions of Glandular inclusion body in lymph nodes are easily missdiagnosed as well-differentiated adenocarcinoma metastatic,so accurate and adequate discrimination about this lesion is needed to avoid over-high of over-low diagnosis.


1. Normal preparations of bronchial muscle respond promptly and quickly to the action of certain pharmacological reagents.

2. Bronchial preparations obtained from pathological lungs even in a very fresh condition, respond to the action of the same drugs much less readily or not at all.

3. This difference in the response between normal and pathological bronchial preparations would seem to indicate that in the latter case there is an impairment of the normal physiological properties of bronchial muscle.


The article examines the issue of the essence of the constitutional and legal status of the monarch of Great Britain. It is noted that the constitutional experience of Great Britain is unique. This country has almost the oldest constitutional history and practice.
The relevance of the research topic is due to the fact that starting from the 17th century the role of the monarch in state administration was constantly changing by permanently reducing the powers of the royal power As a result of the adoption by the Parliament of the Bill of Rights in 1689 and the Act of Organization in 1701, the departure from absolutism and the final establishment of the constitutional monarchy were legally fixed in England.
The article aims to investigate the main aspects of the constitutional and legal status of the British monarch
It is noted that today the monarch is the head of state and the formal source of sovereign power, and also acts as a symbol of the unity of the nation and the guarantor of state continuity and stability in society. In Great Britain, the vast majority of the powers of the head of state are exercised by other bodies, primarily the government and its head, so we can state that the real powers of the monarch in Great Britain are largely limited.
During the reign of Elizabeth II, who will die in 2022, the monarchy was seen more as a symbolic institution representing the united British people. Later, the Eldest son of the late Queen of Great Britain – 73-year-old Charles – came to power. He became the new monarch and received the title of king.
As a result of the research, the authors come to the conclusion that the Monarch is recognized as the source of sovereign power, a symbol of the unity of the nation, and the head of the Anglican and Presbyterian churches. Due to the fact that the Monarch is a politically neutral figure, he acts as a guarantor of stability in the state and society. At the same time, although the monarch is part of the parliament, in English legal doctrine it is customary to put the head of state in the first place in the system of higher state authorities.


Simultaneous lasing of both Ho3+ and Nd3+ in the same crystal of yttrium aluminum garnet (YAG) is reported. The crystal was doped with 10% Ho3+ and 1% Nd3+ ions. Lasing occurred at 2.940 and 3.011 μm due to Ho3+ ion transitions and at 1.064 μm due to a Nd3+ transition. Appropriate mirrors produced simultaneous lasing at 1.064 and 1.339 μm due to Nd3+ ion transitions. The fluorescent lifetimes of both the Nd3+ 4F3/2 and Ho3+ 5I7 states were significantly lower in the doubly doped material than in Nd:YAG and Ho:YAG. This indicates very strong ion‐ion interactions in the (Ho, Nd):YAG crystal.


: Microstrip patch antenna (MPA) with loading of shorting pins expressed as a high gain and planar structure. The inductive e ff ect of shorting pin tunes up the resonant frequency leading to increase the electrical size of antenna and, in consequence, its radiation directivity is enhanced. This work proposes a new con fi guration of MPA with loading of via holes to achieve gain enhancement. The fi eld distribution is analyzed to optimize position of via holes. A prototype of proposed MPA is fabricated and shows excellent realized gain of 11.3 dBi that enhance about by 1.3 dB in comparison to the previous work.


Based on advancing the concept of environmental bearing threshold, combined with dissipative structure theory, the application of the entropy change equation on environmental bearing threshold is preliminarily researched. It also deals with how to analyze the environmental bearing threshold of an environmental system.


The aim of the present thesis was the study of ecclesiastical painting in Greece from 1830 until the early 20th century. Main areas of research were Attic and Central Greece, Peloponnese, islands of central Aegean and South Thessaly. We followed a methodological scheme of four levels of analysis, which are: (a) the churches, the iconographic material and its iconographic analysis, (b) the artist and the stylistic trends, (c) the ideological and social background of the project, (d) the cultural and worship meaning. The main conclusions of our research are as follows: (a) The conditions of freedom created after 1830 helped the ecclesiastical arts to evolve in new ways with the construction of new large churches, the modern decoration and sponsorship activities of local communities. (b) As to the stylistic profile of the ecclesiastical art of the period under consideration, the prevailing view in the literature of a purely westernized orientation proved wrong. In fact, we record several stylistic trends, most of which are 'mixed' and derive their models from the post-Byzantine tradition and western art. (c) The representational system promoted by the official state and church institutions, which its basic principle was the "improvement" of Byzantine art in terms of drawing, perspective and style not entirely dominated. (d) Despite the deviations of the new artistic ideas from the Orthodox theology of the icon we believe that its value should be evaluated on the basis of the broad cultural, theological and ideological connotations of the season. (e) In terms of iconography influences from the West were selective. We see the repetition of past patterns and eclectic introduction of western motifs. Pure western themes are few and not widely spread. (f) This specific nature of the ecclesiastical painting art of the 19th century leads to new methodological interpretations. Therefore, we propose that should be created a new autonomous and interdisciplinary field of the "newest Greek ecclesiastical and religious art" starting from the early 18th century and extending until the post-modernist phase. This branch might borrow methodological tools from the Byzantine Archaeology, History of Art, Theology, Social Anthropology, Cultural Studies (visual studies and visual piety) and compose new interpretative schemes.%%%%Σκοπός της διατριβής ήταν η μeλέτη της eκκλησιαστικής ζωγραφικής στην Eλλάδα από το 1830 μέχρι τις αρχές του 20ου αι. Κύριeς πeριοχές έρeυνας ήταν η Στeρeά Eλλάδα, η Πeλοπόννησος, τα νησιά του κeντρικού Αιγαίου και η νότια Θeσσαλία. Μeθοδολογικά ακολουθήσαμe ένα διeπιστημονικό σχήμα τeσσάρων eπιπέδων ανάλυσης: (α) οι ναοί, οι τοπικές κοινωνίeς, το eικονογραφικό υλικό και η eικονογραφική του ανάλυση, (β) ο καλλιτέχνης η eκπαίδeυσή του και οι τeχνοτροπικές τάσeις, (γ) ο ιδeολογικός και ο κοινωνικός πeρίγυρος του έργου, (δ) η πολιτισμική και η λατρeυτική νοηματοδότηση. Τα κύρια συμπeράσματα της έρeυνάς μας eίναι τα ακόλουθα: (α) Η ανέγeρση νέων μeγάλων ναών μeτά την ίδρυση του ανeξάρτητου eλληνικού κράτους βοηθά την…


Trust is a fundamental consideration for the growth and stability of markets and communities because trust guides decisions about interactions between humans and organizations. New forms of markets and communities are created online, but the very nature of this online environment makes trust management challenging. It is for example common to request services from a website we have never heard of before, and from which we might never request a service again in the future. Combined with perceptions of minimal or non-existent law enforcement, participants in online markets and communities are often vulnerable to many forms of fraud and deception. Reliable perceptions of trust lead to successful interactions and quality online markets, whereas misplaced trust and misplaced distrust are damaging to online interactions and e-commerce. To improve the reliability of trust perceptions and decision making, there is a need to better understand the dynamics of trust in relation to the technological, behavioral, legal and cultural aspects of e-commerce. The call for contributions to this special issue focused on theoretical and practical aspects of trust management; on antecedents to trust; on technologies that impact trust; and on the use of policy, process and technology to manage trust. On this background we received 32 quality submissions from researchers in 24 different countries. After thorough reviewing by independent reviewers, a collection of very high quality articles were selected for publication in the special issue. The research articles in this special Issue give a significant contribution to the body of knowledge and practice in the specific areas of privacy and trust, trust design, collaborative management and trust decisions, trust management systems and the integration of approaches to trust management, multidimensional framework for trust, trust and reputation management, a framework for trust and reputation systems, and the ability to share reputations across communities. The first paper entitled "Sharing Reputation Across Virtual Communities" co-authored by Nurit Gal-Oz, Tal Grinshpoun and Ehud Gudes evaluates a Cross-Community Reputation (CCR) model with the ability to transfer reputation data as part of a user's identity. The second paper entitled "Privacy Issues for Online Personal Photograph Collections" co-authored by Sally Jo Cunningham, Masood Masoodian and Anne Adams uses the Adams' privacy model to investigate information sensitivity, information receiver, and information usage as part of sharing photograph collections. …


Systemic sclerosis (SSc; scleroderma) is a connective tissue disorder that is characterized by an obstructive vasculopathy and by the excessive deposition of collagen in the skin and internal organs. The prognosis is poor in individuals with lung, cardiac, or renal involvement. A safe and effective treatment has not yet been developed. Mesenchymal stromal cells (MSCs) may contribute to the pathogenesis of autoimmune diseases (1). MSCs can differentiate into mesenchymal cells, such as bone or muscle cells, but also into endothelial cells. Significantly, MSCs from patients with SSc have an impaired ability to differentiate into endothelial progenitor cells and to contribute to vasculogenesis (2). MSCs are capable of suppressing both the innate and the adaptive immune systems. In vitro, they inhibit the proliferation of T lymphocytes (3) and the function of B lymphocytes (4). MSCs are not recognized by alloreactive T cells in vitro (5) and exert immunosuppressive effects regardless of HLA and species boundaries (6). A specific mechanism that could explain these effects has not been defined. Even though conclusive evidence is still missing, MSCs have shown promising activity in refractory graft-versus-host disease (GVHD), especially in cases with a scleroderma-like course (7), and may offer a new treatment approach (at least in subgroups of patients with GVHD). Here we report the first data regarding MSC transplantation from allogeneic related donors into SSc patients. MSC transplantation was performed in 5 white patients with progressive SSc who were positive for Scl-70 antibodies (except patient 5, who was positive for anti–RNA polymerase III antibodies). In each case, the treatment was approved by the local ethics committee, and patients and donors or the respective legal representative provided written informed consent. After administration of a local anesthetic, 20–120 ml bone marrow was aspirated from the iliac crest of each donor, using sodium citrate as an anticoagulant. All subsequent procedures were performed at a certified facility. After centrifugation at 300g, cells were resuspended with phosphate buffered saline (PBS), overlaid on leukocyte separation medium (1,077 gm/liter), and centrifuged for 30 minutes at 300g. Bone marrow mononuclear cells (BMMCs) were harvested and resuspended with growth medium. After centrifugation at 300g, cells were plated in growth medium at 1–2.5 10 BMMCs/cm. Cultivation was performed with 5% CO2 and 98% humidity, at 36°C. For patient 1, growth medium consisted of low-glucose Dulbecco's modified Eagle's medium (DMEM), 100 units/ml penicillin, 100 g/ml streptomycin, and 2% fetal calf serum. For patients 2–5, growth medium consisted of low-glucose DMEM, 2.7% human platelet apheresis lysate, 4.6% fresh frozen plasma, and 1.8 units/ml unfractionated heparin. At 50–80% confluence, cells were detached with trypsin, counted, and seeded at 2 10–2 10 BMMCs/cm. Medium was changed every 2–3 days. Upon reaching passage 4 or a cell number of 1 10 cells/kg donor body weight, cells were harvested. For final packaging of the noncryopreserved product, cells were centrifuged at 300g and resuspended in PBS containing 5% human serum albumin (HSA). For packaging for subsequent cryopreservation, cells were resuspended in PBS containing 10% DMSO and 5% HSA. Cryopreservation was performed automatically (Biosafe 200; MesserCryotherm). Microbiologic analysis was performed at the passage before final packaging and from a probe of the final packed product. MSCs were characterized in patients 1, 4, and 5 as CD34 , CD45 , CD14 , CD19 , HLA–DR–negative, CD105 , CD90 , and CD73 , using a 4-color flow cytometer. Cytogenetic testing of MSCs was not performed. Intravenous infusion was used to transplant MSCs. Patients 1 and 2 received freshly prepared MSCs, whereas patients 3–5 received cryopreserved MSCs (which was necessary for logistic reasons). Vital functions were monitored for 60 minutes. After MSC transplantation, patients were monitored weekly for 1 month, biweekly for 2 subsequent months, and then once per month after that point. Beginning 6 months after MSC transplantation, patients were seen once every 3 months. The modified Rodnan skin thickness score (MRSS) (8) was determined before MSC transplantation and every 3 months thereafter. The functional ability was assessed by the Health Assessment Questionnaire (HAQ) (9). The number and size of acral ulcerations were documented by digital photography before treatment, and at 6 weeks, 3 months, and 6 months after treatment. Lymphocyte subpopulations (i.e., B cells [CD19 ], T cells [CD3 ], T helper cells [CD4 ], cytotoxic T cells [CD8 ], and natural killer cells [CD16 CD56 ]) were determined by flow cytometry. Pulmonary function analyses, including forced vital capacity (FVC) and diffusing capacity for carbon monoxide (DLCO), as well as echocardiography, vascular ultrasound examination of the fingers, and determination of transcutaneous partial oxygen pressure of the skin of the forearms, were performed before MSC transplantation and every 3 months afterward. Patients who had pulmonary involvement underwent high-resolution computed tomography (HRCT) every 6 months. All patients tolerated MSC transplantation without immediate toxicity. Mild respiratory tract infections that did not require hospitalization occurred during followup (Table 1). The levels of antinuclear antibodies remained unchanged. Of the 5 patients, 4 had at least temporary improvements in the MRSS (Table 1). Acral necroses improved or healed in all 3 affected patients. In these cases, a tendency toward improved oxygen saturation over the involved tissue was seen 3 months after MSC transplantation. Pulmonary function remained stable in all patients except in patient 2 (data not shown). Lymphocyte subpopulations did not change significantly. No significant alterations in HAQ scores were seen. Additional details on the patients' courses are available online at http:// www.medizin.uni-halle.de/rheumazentrum/index.php?id 341. Patient 1 presented with progressive involvement of


L‐forms of the halo blight pathogen, Pseudomonas syringae phaseolicola, were maintained in a medium which suppressed cell wall synthesis. These L‐forms, unlike revertants (walled forms derived from unstable L‐forms) and cell walled (parent) organisms, did not elicit a hypersensitive response in tobacco leaves. Association of L‐forms with Phaseolus vulgaris was established by seed imbibition in L‐form suspensions compared with appropriate control treatments (5% mannitol or heat‐killed cells). Seedling emergence and plant growth was not affected by L‐form imbibition. The association was detected by agglutination assays using polyclonal antibody. The L‐form association was localized to the lower shoot tissue and was progressively lost with age of plants. Plants with associated L‐forms had vigour and shoot weights equivalent to controls and showed no disease symptoms. The cell walled form could not be isolated from plants showing positive agglutination. On challenge with the pathogen, plants associated with L...


Most language resources and technologies depend on written text, while most endangered languages are primarily spoken. Transcribing speech into text is time consuming and error-prone. We propose a method for finding spelling inconsistencies without recourse to a standard reference dictionary or to a large training corpus, by repurposing a method developed for finding annotation errors. We apply this method to improve quality control of audio transcriptions, with particular focus on under-resourced, primarily oral language varieties, including endangered varieties.


Abstract : This is a multi-investigator program, involving an integrated theory and modeling, synthesis, nonlinear optical spectroscopy, and electronic characterization effort, that is being undertaken by the Perry, Bredas, Kippelen and Marder groups. The activities being pursued under this AFOSR program are: 1) development two-photon absorbing molecules with large two-photon cross sections and excited-state absorption cross sections for optical power limiting applications, 2) chromophore/ nanoparticle assemblies with enhanced nonlinearity for optical power limiting applications, and 3) advanced organic transport materials for photovoltaic/photoconducting applications.


Laminate film having a combination of the piezoelectric layer (1) and non-piezoelectric layer (2) which changes the size with the applied voltage is disclosed. The laminate structure, it is possible to form the optical film switchable wide range of electrically. These films have a display, a polarizer, optical compensation plate, the aesthetic manner films and only the wavelength of certain of the selectively reflecting "hot" and "cold" in applied to the mirror. Also disclosed are monochrome and multicolor display using these films.


The presence and distribution of mammals in remote areas are currently poorly known, although these areas are usually rich in biodiversity. The main objective of this study was to characterize the terrestrial mammal community within the reserve of Huinay, southern Chile, using three methodologies: i) questionnaires to residents and visitors to the area (n=42); ii) transects of mammals' presence (scats, tracks, etc; the total length of transects was 80 km); iii) camera-trapping (18 camera-traps were set with a total sampling effort of 590 trap-days). A total of 13 species of mammals were identified, and only three of them (pudu, Pudu puda, kodkod, Leopardus guigna and lesser grison, Galictis cuja) were recorded with all the methods employed. Our results suggest that different methodologies can complement each other for surveying species presence and distribution in remote areas.


We have previously demonstrated that power loss (PL) through the total cavopulmonary connection (TCPC) in single ventricle pts undergoing Fontan can be calculated by computational fluid dynamic (CF...


A new approach to the synthesis of fused nitrogen-containing heterocyclic compounds has been developed, involving cyclocondensation of Schiff bases or their synthetic precursors with 2-heteroarylcyclohexane-1,3-diones.


More than two thirds of the individuals who have strokes are over the age of 65. Therefore, as the global population continues to age, the risk of stroke is expected to increase substantially. Virtual reality (VR) is an emerging therapy that holds promise for the rehabilitation of patients with chronic stroke conditions. VR is an interactive, computer-based simulation of real life tasks, occurring in real time. The aim of this review was to explore whether non-immersive VR could be used to effectively improve fine motor function of the affected upper extremity in patients with chronic stroke. Ten studies examining non-immersive VR for the purpose of chronic stroke rehabilitation were included for review. Studies utilized a variety of VR-based interventions, reporting trends toward improvement on nearly all outcome measures. Results were examined at the levels of "body structure and function" and "activity" according to the International Classification of Functioning. Across the studies, significant improvements were reported for the Jebsen Test of Hand Function, the Box and Block Test, participants' finger fractionation, finger tracking measures, and time from peak hand velocity to movement of an object. However, considerable variability in participants' recovery rates of fine motor function across the studies suggests that the results should be interpreted with caution. More research using randomized controlled trial designs will clarify evidence surrounding the amount of improvement that can be experienced with non-immersive VR-based interventions. This review provides justification for continued investigation within the field of motor skill recovery in patients with chronic stroke.


bidentate diimino complex wherein the complex is represented by the following formulas: wherein: M is nickel or palladium; n is 0, 1, 2 or 3; m is 1, 2 or 3; each X, same or different, is selected from a group consisting of: halogen, hydrogen, OR, N (R) 2, R; wherein R is selected from the group consisting of: C1-C20 alkyl, C3-C20, C6-C20 aryl, C2-C20 arylalkyl C7-C20 alkylaryl C7-C20 arylalkenyl C8-C20, and alkenylaryl C8- C20 linear or branched; two X taken together can also form an aromatic or aliphatic divalent ligand, containing two equal or different donor atoms belonging to the group 14-16 of the periodic table; each R1, same or different, is selected from a group consisting of: hydrogen, an aliphatic hydrocarbon group or monovalent aromatic, optionally containing heteroatoms of group 14 to 16 of the periodic table or boron, provided that at least one R1 group is represented by the formula: R4OSi (R) 3; in which each R, same or different, is selected from the group consisting of: C1-C20 alkyl, C3-C20, C6-C20 aryl, C2-C20 alkenyl, C7-C20 arylalkyl, alkylaryl C7- C20 arylalkenyl C8-C20, and alkenylaryl C8-C20 linear or branched each R4, same or different, is an aliphatic hydrocarbon group or divalent aromatic containing 1 to 20 carbon atoms, optionally containing between 1 to 5 heteroatoms of groups 14 to 16 of the periodic table and / or boron; each R2, same or different, is a radical containing from 1 to 20 carbon atoms; this group optionally contains heteroatoms of groups 14 to 16 of the periodic table and / or boron; each R3, same or different, is hydrogen or a radical containing from 1 to 20 carbon atoms; this group optionally contains heteroatoms of groups 14 to 16 of the periodic table and / or boron; two or more of R1, R2, R3 and R4 may also be joined to form an aliphatic or aromatic 4 to 15 membered ring; the ring may contain heteroatoms optionally Group 14 to 16 of the periodic table of elements and / or boron.


As electronic products turn into the integration and miniature,Electronic Design Automation (EDA) is becoming one of the necessary tools in the RD of electronic products.In order to enhance the education and research level in the area of information high technology,an EDA central laboratory had been set up for sharing the EDA tools in campus networks.This paper introduced the sharing management,tools configuration,laboratory construction of EDA center.How to utilize the resource of EDA center for education and research was also expounded in this paper.


Overture On this, the thirteenth appointment with Grout Line, we have an article from Germany. The Grout Line seems to be more international with each issue! This issue's article is related to liquefaction and the use of Jet-Grouting for its mitigation. The author is Giovanni Spagnoli MASc (spagnoli_ firstname.lastname@example.com) who is actually working as a researcher on liquefaction problems at Marum Marine Geotechnics, Bremen, Germany.


e15632Background: Hepatocellular carcinoma (HCC) represents one of the most common causes of cancer related deaths worldwide. Bone metastases from HCC are infrequent, with a reported incidence rang...


In this study, a new design approach using HFPSO algorithm, which is obtained by hybridization of firefly algorithm (FA) with particle swarm optimization (PSO) algorithm is presented for the adjustment of proportional-integral-derivative (PID) controller parameters in a buck converter. Using the proposed approach, it is aimed to improve the stability profile of the relevant system. In order to demonstrate the superiority of the proposed HFPSO-based PID (HFPSO/PID) controller, stability analyzes in time domain and frequency domain, and disturbance suppression analysis were performed comparatively. The results obtained from analyzes showed that the proposed HFPSO/PID controller is more efficient than the whale optimization algorithm (WOA) based PID (WOA/PID) controller and genetic algorithm (GA) based PID (GA/PID) controller to improve the control performance of the buck converter.


To obtain data on the reaction kinematics of the sequence of reactions in one or more samples of compositions is optically monitored at a plurality of discrete measurement locations. According to successive frames are each incorporated the whole of the measurement sites during the expected duration of the reactions to register the light signals. The evaluation of the light signals by analysis of the measurement sites reproducing image sections of the recorded individual images.


L–Au–[TsC(CN)2] are new cationic gold catalysts with a carbon based counterion, which are widely applicable for gold catalyzed reactions. For reactions which need highly reactive gold catalysts, a Lewis acid co-catalyst can be added to increase the reactivity of L–Au–[TsC(CN)2]. L–Au–[TsC(CN)2] also have advantages of easy reaction steps and high functional group tolerance.


In this study, the potential of rust as a pigment in paint technology via sintering process was investigated. Iron (III) nitrate was the raw material used to make rust or iron oxide. The characteristics of iron oxide were analyzed. Moreover, iron oxide was mixed with other chemical components to make paint. The properties of paint in both liquid state and solid state were determined by portable field viscometer, pH indicator, glossmeter, pencil hardness test, and tape adhesive test. The optimum ratio of paint components for this study where used iron oxide as pigment. The other properties of pigments and paints will be conducted in the analysis study.


Two finite difference methods for time-fractional subdiffusion equation with Dirichlet boundary conditions are developed. The methods are unconditionally stable and convergent of order (τq+h2) in the sense of discrete L2 norm, where q(q=2-β or 2) is related to smoothness of analytical solution to subdiffusion equation, β(0<β<1) is order of the fractional derivative, τ and h are step sizes in time and space directions, respectively. Numerical examples are provided to verify theoretical analysis. Comparisons with other methods are made, which show better performances over many existing ones.


PROBLEM TO BE SOLVED: To provide a manufacturing method of a control valve type mono-block lead storage battery easy to manufacture and capable of preventing dilute sulfuric acid electrolyte solution from creeping up from a gap between a battery can barrier rib 4 and a welding protrusion 16. SOLUTION: Silica fine powder 25 is added to dilute sulfuric acid 22 which are stirred with a planetary type stirrer 27 to manufacture gel electrolyte solution 20. The gel electrolyte solution 20, after being weighed, is filled in a top part of an electrode plate group 12 of the lead storage battery 21 through a tube 31 plugged into a safety valve cylinder 27 with the use of a roller type pump 29b. Here, a notched part 19 is provided at the safety valve cylinder 27 of the lead storage battery 21. COPYRIGHT: (C)2010,JPO&INPIT


The mesh size and time increment, other than the CFL condition, essential to obtain tsunami run-ups with sufficient accuracy for practical applications are examined. It is found that more than 20 spatial grid points should be included within a local wave length for obtaining reasonable wave heights. This criterion is applied to a numerical simulation of the Nihonkai-Chubu earthquake tsunami in 1983, the measured run-up heights and inundated areas of which supply plentiful data for comparison. The present computation reproduced very well the spatial distribution of tsunami run-ups and those maximum values.


The school discipline literature has expanded rapidly in recent decades, yet the conceptualization and measurement of school discipline patterns remains overlooked. In this paper, we present a comprehensive analytic framework to examine school discipline patterns that encompasses school-level metrics that capture the prevalence and disparity in exclusionary discipline and regression-based approaches that examine the likelihood that students experience exclusionary discipline. We apply the framework to New York City and, based on school-level metrics, find that Black students have the highest prevalence and the highest disproportionality. Results from regression models affirm that Black students are most likely to receive office discipline referrals and suspensions and experience differential processing of suspensions for similar categories of infractions. The findings illustrate the nuances of the disciplinary process in schools and inform the consideration of a range of available analytic tools that educational stakeholders may employ to better measure and understand exclusionary discipline.


Three-dimensional (3D) compressible carbon-based foams with ultralow density, high porosity and excellent electrical conductivity have aroused considerable interest especially as pressure sensors, recyclable absorbents and for other advanced applications. Herein, highly compressible 3D graphene/carbon nanotube foams (GCFs) were prepared by a facile self-assembly process under mild conditions. The incorporation of CNTs into graphene resulted in great improvement of their mechanical and compressible properties compared with the graphene-only foam (under a high strain of 80% and a higher stress of 25.64 kPa). Besides, the GCFs exhibited excellent piezoresistive properties with high sensitivity (with a high gauge factor of 8.4 at a strain of 10%) and great stability during the compression cycles which was quite important for the pressure sensors. In addition, the compressible GCFs also possessed excellent adsorption capacity for organic solvents with great reusability. With unique electrical features and high sensitivity as well as robust mechanical strength, the as-fabricated 3D GCFs possess great potential as elastic pressure sensor materials, absorbents and beyond.


The invention discloses Chinese medicinal external application paste for treating lumbar muscle wrench. According to the traditional Chinese medical science, waist muscle injury causes qi depression to blood stasis, blockage of channels and pain caused by stagnation of qi and blood. The Chinese medicinal external application paste is prepared from Chinese medicines having the effects of relaxing and activating the tendons, promoting blood circulation and stopping pain including green tangerine peel, rose, dalbergia wood, corydalis tuber, safflower, cowherb seed, sappan wood, fortune's drynaria rhizome, tuber fleeceflower stem and Vaseline according to the preparation way of Chinese medicinal cataplasm. As proved by clinical tests in the department, the curative rate of the Chinese medicinal external application paste is 81.7 percent, the total effective rate is 100 percent, and the paste is worthy of clinical popularization and application.


This paper describes a 1,500 metric ton, mobile, remotely operated worksystem that has been designed to excavate and retrieve buried hazardous and low level nuclear waste. The mobile worksystem includes seven independent, multi-degree-of-freedom, telerobotic excavation tools and four remotely operated, double-lid transfer systems to move the waste through the system's negative pressure confinement barrier. Ten human operators in a separate building control the worksystem's functions from computer based control consoles communicating over a fiberoptic umbilical. A computer controlled anti-collision, radiation monitoring, and mapping system keeps track of each tool's position and prevents inadvertent excavation of high radiation sources. The mobile worksystem structure is a bolted joint, steel gantry approximately 75 meters long, 30 meters wide, and 20 meters high mounted over a 38 meter wide pit. The pit surface is completely confined by geomembrane liners deployed by the mobil worksystem during the retrieval operation. Fig. 1 OVERVIEW OF THE MOBIL WORKSYSTEM Work supported by the U. S. Department of Energy, Assistant Secretary for Environmental Management, under DOE Idaho Operations Office Contract DE-AC07-94ID13223


ZnCl 2 (5 mol%) is an efficient catalyst for the thiolysis of 1,2-epoxides by thiophenol in water at pH 4.0. A variety of β-hydroxy phenylsulfides were obtained in short reaction times and excellent yields. Starting from cyclohexene oxide (1), two one-pot multi-step procedures in sole water (thiolysis/oxidation with H 2 O 2 ) have been realized, for the chemoselective synthesis of the corresponding β-hydroxysulfoxides 19 or for the related β-hydroxysulfone 20.


Objective To establish the rat model of retinal light injury,and observe the effect of Compound Light Capsule on the rat retinal light injury under electron microscope.Methods 30 SD rats(60 eyes)were divided into high dose group,middle dose group,low dose group,sham group,and normal group in random,6 SD rats(12 eyes)in each group.Rats were intragastrically administered with Compound Light Capsule 7 days before modeling,and the administration lasted for 2 weeks.Experimental rats in each group were exposured to the light away from the corner(150±3) mm except the normal group.The illumination of eyes in the horizontal position of operation microscope was(22 000±1 000) lux,and continue light exposure for 30 minutes.The administration for another 1 week after exposure to the light.The retinal morphology changes of each group were observed under electron microscope.Results Normal rats had clear layers of retinal structures,the inner and outer segments of rod cells were in a neat and orderly arrangement.The inner and outer nuclear layer arranged in sequence and stained evenly.Each group was observed a thinner and sparser change in the outer nuclear layer after light exposure.The outer segments of rod cells arranged disorderly,part of the membranous discs were ruptured.Swollen mitochondria of the rod cells in inner segments were also observed.Outer nuclear layer cells showed karyopycnosis and maldistribution.The changes in each dose group were improved compared with sham group.Conclusion The establishment of the retinal light injury model is successful by using the operating microscope.Each dose of Compound Light Capsules shows a protective effect on retinal light injury.


The invention relates to the field of microbial fermentation and specifically to an Aspergillus niger and a method of applying the Aspergillus niger in fermenting bamboo shoots or bamboo shoot residues for improvement of the content of phytosterol. According to the invention, the Aspergillus niger is separated and screened from rotten bamboo shoot residues and is then domesticated so as to obtaina novel Aspergillus niger strain which is assigned the accession number of CCTCC No. M2011428 and is capable of high yield of phytosterol. The invention also provides the method of applying the Aspergillus niger with the accession number of CCTCC No. M2011428 in fermenting bamboo shoots or bamboo shoot residues so as to improve the content of phytosterol. The method enables the dry weight of phytosterol to increase from 412.5 to 523.4 mg/100g before fermentation to 701.2 to 1184.5 mg/100g and allows fermentation time to be shortened simultaneously. According to the invention, pollution of bamboo shoot residues to environment is reduced, economic benefits of bamboo shoots are improved, and the industrial process of in-depth exploitation of bamboo shoot residues for preparation of phytosterol is effectively promoted.


Objective:To study the deficits of visual short term and working memory ability in reading disabled children. Methods:Use the on-line experimental design (simple and complicated figures) to compare the difference between RD and normal children in visual short-term and working memory ability. Results: (1) The RD children are not different from the normal children in the visual short-term memory ability;(2)The RD children have deficits in the visual working memory ability both on the simple and the complex experimental material. Conclusions: The deficits in visual working memory represent the main character in memory area in RD children.


Architecture of high-rise buildings depends on many factors, which greatly vary from initial concepts, functionality of designed spaces, its proportions to human perception and urban context, and structural support and technological capabilities to support desired concept. Thus, in any analysis of the factors that architecture depends on is its structural support, which has to fulfill four primary structural requirements: static equilibrium, stability, strength and rigidity of the structure. A turnover for fast development in construction of high-rises occurred in the second half of the 20th century; strong economy forced and supported technological developments, and even the new generation of computers and software helped in the development of more efficient structural systems. Innovative structural systems such as tubular forms, outriggers, diagrids and megastructures enabled design and construction of high–rise structures as common thing and inevitable part of new living style.


The utility model discloses a degassing unit that disinfects on garlic rice surface belongs to the food sterilization field. It is main including ozone generating device, tubular metal resonator, microbubble generating device, anemostat, dissolving device, ozone water pipeline, garlic rice container, the export of ozone generating device is connected to microbubble generating device entry through the tubular metal resonator, and microbubble generating device entry is connected to dissolving device through the anemostat, and dissolving device is connected to garlic rice container through ozone water pipeline. Its realization mode is that ozone generating device produces ozone, and the ozone of production is carried to the microbubble generating device in, and microbubble that microbubble generating device produces contains ozone is carried to the dissolving device in, can evenly dissolve a large amount of microbubbles that contain ozone in the short time in the dissolving device, generates high concentration ozone water promptly, then carries to garlic rice container, reaches disinfection's purpose. The utility model discloses have disinfection effectual, do not have influence, safe and reliable, no secondary pollution to product quality.


Future 3D monitors will display autostereoscopic multi views, because these offer a more stress-free perception then 2D screens. But this needs a very high colour pixel resolution which can be achieved by organic light emitting diodes that mean OLED technology. This paper presents the concept and realisation of a high-resolution 3D sample. The OLED technology has the advantages of flexible designing of the pixel arrangement, high brightness and low power consumption, wide view observing angle, without to change the light intensity and colour characteristics in comparison with TF. These are very important features for designing new types of high quality 3D displays. We have produced a small 3D demonstrator that offers a multiple of depth levels for one or many observers simultaneously. Using of wide-angle lenticular glass, mounted in front of the high resolution OLED raster, is the working principle. The sample offers up to 112 different views horizontally of the presented scene, up to 5.44 millions pixels in b/w, and the visible size is up to 2.2 inch. The pixel structures are etched on an Indium Tin Oxide (ITO) substrate via photolithography process.


Introduction: CD34+-selected peripheral blood stem cell infusions without conditioning have recently been utilized for poor graft function (PGF) with promising results. Unfortunately, many patients have been unable to receive the boost infusion as their donors were unwilling or unable to undergo an additional stem cell collection. Therefore, we conducted this pilot trial utilizing either fresh or cryopreserved peripheral blood stem cell products to create CD34+-selected peripheral blood stem cell infusions for the treatment of PGF. Additionally, to explore relationship of CD34+ dose and response we included a cohort of donors mobilized with plerixafor in addition to the standard G-CSF. Methods: Poor graft function (PGF) was defined as ANC 500/μl without growth factor support for >7 days; platelet improvement was defined as platelet count ≥ 50,000/µl without platelet transfusion support for > 7 days; and RBC improvement was defined as hemoglobin > 9 g/dL and transfusion independence. Complete response was defined as improvement of all involved cells lines; partial response was defined as improvement of platelets and/or neutrophils with continuing RBC transfusion dependence. Results: The mean post-selection CD34+ count per kg of recipient weight was 3.7x106, 12x106, and 1.7x106 for G-CSF only, G-CSF plus plerixafor, and cryopreserved products, respectively. Mean CD34+ yields (defined as the number of CD34+ cells after selection/CD34+ cells prior to CD34 selection) was 58%, 67%, and 31% for G-CSF only, G-CSF plus plerixafor, and cryopreserved products, respectively (Table 1 and Figure 1). The mean number of CD3+ T cells/kg infused in each product was 0.004 x 106, 0.032 x 106, and 0.015 x 106 for G-CSF only, G-CSF plus plerixafore and cryopreserved groups respectively (Table 1). Following the CD34+-selected stem cell infusion, 12 of the 17 recipients (71%) had a complete response including all 3 who received cryopreserved products; 3 had a partial response (17%) and 2 patients (12%) did not respond. One year relapse-free and overall survival was 71% and 65%. There was no treatment related toxicity reported other than graft-versus-host-disease (GVHD); three (18%) developed acute GVHD (1 grade I localized to the skin, 2 grade II with gut involvement), 6 chronic GVHD (2 limited and 4 extensive) (Table 1). Conclusion: Cryopreserved products seem to be a viable alternative to create CD34+ -selected peripheral blood stem cell infusions for the treatment of PGF. When collecting fresh products is an option, the addition of plerixafor increases CD34+ yield over G-CSF alone. Disclosures Abboud:Teva Phamaceutical: Research Funding. Uy:Novartis: Research Funding.


Vehicle dispatching plays an important part in improving event reaction ability, saving rescue time and reducing property losses in urban traffic emergency systems. Combined with characteristics of emergency rescue, an optimal object based on the shortest emergency time is established and proved to satisfy the definition of the best dispatching plan. An algorithm based on convex combination method is also proposed. Finally, an example illustrates that the optimal objective is rational and the algorithm is effective.


The study was undertaken to characterise the groups of phytoplankton in four lakes (Ósemka, Uli, Cyganek and Baba) supplied by the Cybinka River (a right tributary of the Cybina River). Lakes Ósemka and Uli were classifi ed as mezo-eutrophic, while lakes Cyganek and Baba as eutrophic. The phytoplankton of these lakes was composed of taxa. The greatest contribution in the number of taxa was brought by chlorophytes. In the other lakes down the course of the river the abundance and biomass of the phytoplankton were greater and the contribution of particular taxonomic groups changed. In Lake Ósemka the most abundant were the representatives of cryptophytes ( %) chrysophytes ( %) and chlorophytes ( %). In Lake Uli the dominant contribution was brought by cryptophytes ( %). In Lakes Cyganek and Baba the dominant group was cyanobacteria whose contribution was % in Lake Cyganek and % in Lake Baba.


How to evaluate and interpret an article about therapy or therapeutic procedures Independent of the thematic area and design employed, it was verifi ed that between 40% and 60% of published studies in surgical scientifi c journals are related with treatment or therapeutic procedures (TP). The aim of this manuscript is to present a synthesis of the key elements for proper writing, reading and assessment of articles related with treatment or TP, regardless of disciplinary area which has arisen in the investigation. Who writes a manuscript relating to treatment or PT, or who read an article of this type should require at least a clear, accurate and concise objective, on the stage of the research being conducted, the explicit mention of the design used with the respective methodological details inherent in this, and the endorsement and implementation of statistical tools and measures of association, or at least the numbers needed to calculate these values. Key words: "Therapeutics" [Mesh], "Therapy" [Subheading], Therapeutic procedures, Treatment, "Cohort Studies" [Mesh] "Clinical Trial" [Publication Type], "Review" [Publication Type], "Meta-Analysis" [Publication Type], "Risk" [Mesh].


The size, turnover time and transfer rate of the glucose pool were estimated with glucose–C 14 in normal and ketotic cows. The size and turnover time of the pool were both about 1/5 greater in the ketotic than in the normal cows, so that the transfer rate remained similar, being about 1 gm/min. The hypoglycemia which is characteristic of the disease appeared to be associated with an expansion of the glucose space, which in the normal cows approximated the extracellular volume, into the intracellular compartment of the ketotic cows. These results do not favor theories of bovine ketosis which presume a shortage of body glucose. Submitted on June 25, 1959


This study aimed to identify the language function in tweets from @onlyjiungs. The @onlyjiungs Twitter account's tweets served as the study's source of data. Purposive sampling and the descriptive qualitative approach were utilized in this study to get the answers to its research questions. The findings indicated that among the 31 data, the referential function (14 utterances, or 45,2%) is most frequently used, followed by the expressive function (11 utterances, or 35,5%), the phatic function (2 utterances, or 6,4%), the metalingual function (0%), the conative function (2 utterances, or 6,4%), and the poetic function (2 utterances, or 6,4%). The tweets from @onlyjiungs met every requirement in Hymes' (1974) theory of context SPEAKING, showing that context SPEAKING on a tweet from @onlyjiungs answers every requirement of the theory. The tweets were taken from September 2021 through October 2021. The goals of @onlyjiungs' tweets were intended to be represented and expressed in the final sections of the Twitter post outcomes. The following social act update about Jiung's life was provided by @onlyjiungs. She underlined a particular statement she made in the tweets. Because, they were intended for teens their age, @onlyjiungs's tweets are also frequently written in a casual tone. The typical Twitter tweet mostly focused on describing the purpose of and the message included inside it. The kind of utterances from those tweets generally had a stronger referential function since those Twitter postings' primary purpose was to notify @onlyjiungs' followers who are the readers. Keywords: language functions, context, pragmatics, twitter


Tb2O3 coated with a polysiloxane layer is a biocompatible nanoscintillator that exhibits an appropriate pattern of biodistribution after injection. In this contribution, we combine this nanosystem with porphyrin molecules that are able to generate singlet oxygen, a major cytotoxic agent for photodynamic therapy application. Using time-resolved laser spectroscopy and singlet oxygen probes, we demonstrate this combination is suitable for singlet oxygen generation induced by X-ray and provide a physical study of the energy transfer observed between the nanoscintillator and the porphyrin. Combined with a radiotherapy protocol, the proposed nanohybrid system presents a combination of physical, chemical, and biological properties that make it a good candidate for photodynamic effects in deep tissues.


In this paper, topological-mathematical models based on multilineal regression analysis have been built as a model of the degradability of 26 alkylphenols through the Chemical Oxygen Demand (COD) and Biochemical Oxigen Demand (BOD5). Two models with three-variable were selected (r2= 0.8793 and q2=0.8075 for log(1/COD) and r2= 0.8928 and q2=0.8327 for log(1/BOD5). The models were validated by cross-validation, internal validation and randomization tests. The results, which stand in good accordance with the obtained results, confirm the robustness of the method.


Diploma work concerns with problems connected to self-regulation learning in students of helping professions at Tomas Bata University in Zlin, Czech Republic, mostly in aspect of self-determination theory. Work is focused to determine current self-regulated learning rate of earlier mentioned students and its effects on study at university. Theoretical part is based on the cornerstones of self-regulation learning and deals with inner and outer factors of self-regulation. It also deals with the development of self-regulation and helping professions. The practical part is focused on the detection rate of self-regulated learning in students helping profession due to their age, academic achievement, the form and the type of study. It summarizes the findings and offers recommendations for practice.


We study the cosmological evolution of scalar fields with arbitrary potentials in the presence of a baryotropic fluid (matter or radiation) without making any assumption on which term dominates. We determine what kind of potentials $V(\ensuremath{\varphi})$ permits a quintessence interpretation of the scalar field $\ensuremath{\varphi}$ and to obtain interesting cosmological results. We show that all model dependence is given in terms of $\ensuremath{\lambda}\ensuremath{\equiv}\ensuremath{-}{V}^{\ensuremath{'}}/V$ only and we study all possible asymptotic limits: $\ensuremath{\lambda}$ approaching zero, a finite constant, or infinity. We determine the equation of state dynamically for each case. For the first class of potentials, the scalar field quickly dominates the universe behavior, with an inflationary equation of state allowing for a quintessence interpretation. The second case gives the extensively studied exponential potential, while in the last case, when $\ensuremath{\lambda}$ approaches infinity, if it does not oscillate, then the energy density redshifts faster than the baryotropic fluid, but if $\ensuremath{\lambda}$ oscillates, then the energy density redshift depends on the specific potential.


ABSTRACT
 The rights of victims at the International Criminal Court ('ICC' or 'Court') mirror their normative rights in international human rights law – victims' rights to truth, justice, and reparations. However, the reality of victim participation is oftentimes formalistic, overlooking victims' priorities. This is demonstrated by the lesser importance given to violations of social and economic ('ES') rights by the ICC, which are privileged by victims as being central to addressing their immediate needs, and are often a contributing factor to the root causes of conflict. This article suggests three ways in which the ICC can incorporate an ES rights perspective within its victims' mandate, by reference to the case of The Prosecutor v. Dominic Ongwen. Firstly, the ICC must ensure a broad interpretation of truth where socio-economic causes and effects of conflict are considered as part of victims' right to the truth in judicial pronouncements. Secondly, the Office of the Prosecutor must ensure that socio-economic violence is broadly reflected within the scope of the charges brought forward against an accused person/s where relevant. Lastly, the ICC Trust Fund for Victims must act with speed to ensure immediate assistance to victims and reparation orders must seek to dismantle pervasive systems of structural inequalities.


When using a symmetric encryption algorithm, specifically the AES, the Block Cipher Mode of Operation to be used must be specified. Usually choosing the mode of operation is influenced by two main factors: 1. Security; and the 2. Performance of the mode. Most of the related literature explores the security of the modes. In contrast, this research paper explores, compares and evaluates the performance of the five modes of operation recommended by the National Institute of Standards and Technology (NIST). A code using Crypto++ cryptographic library has been developed to benchmark the performance of these modes. Based on the conducted experiments and obtained results, the Counter mode of operation has been found generally superior to the other four modes of operation in terms of performance especially when increasing the input size.


The expansive soil of highway reconstruction project was improved by using weathered sand which was widely distributed in Yichang. Through an indoor swell-shrink index test,a conclusion could be drawn that the improved expansive soil could significantly inhibit the swell-shrink characteristics. Through an indoor CBR test,another conclusion could be drawn that expansive soil mixed with weathered sand could obviously improve the CBR value and reach the standard of subgrade filler. The influence of different initial dry density and different sand proportion influence on CBR value of expansive soil were discussed. The results showed that: the initial dry density and the proportion of mixing sand had great influence on CBR value. At a certain initial dry density,the CBR value increased with the increase of sand ratio. At a certain sand proportion,the CBR value increased with the increase of initial dry density. CBR value and initial dry density expressed power relation. When initial dry density was small,CBR value and sand ratio expressed the linear relationship; when initial dry density was high,CBR value and sand ratio expressed the exponential function relationship.


Near-infrared imaging and spectroscopy have been obtained of the gravitationally lensed galaxy at z=4.92 discovered in Hubble Space Telescope (HST) images by Franx et al. Images at 1.2, 1.6, and 2.2 μm show the same arc morphology as the HST images. The spectrum with resolution λ/Δλ~70 shows no emission lines with equivalent width stronger than 100 Å in the rest-frame wavelength range 0.34-0.40 μm. In particular, [O II] λ3727 and [Ne III] λ3869 are not seen. The energy distribution is quite blue, as expected for a young stellar population with the observed Lyα flux. The spectral energy distribution can be fitted satisfactorily for such a young stellar population when absorption by dust is included. The models imply a reddening 0.1 mag<E(B-V)<0.4 mag. The stellar mass of the lensed galaxy lies in the range of 2-16×109 M☉. This is significantly higher than estimates based on the HST data alone. Our data imply that absorption by dust is important to redshifts of ~5.


Many colorful characters are one of the artistic charms of Wuthering Heightswritten by Emily Bronte.In the past one and half century,what has been most noticed and commented is undoubtedly the two main characters—Catherine and Heathcliff.However,Nelly,the seemingly unimportant person should not be totally neglected,because Emily endows her with multiple identities as a woman housekeeper,a surrogate mother and a first-person narrator,which mak her another powerful character in the novel.


A system for accelerating web page delivery is provided. A method is disclosed that includes running a web browser on one or more servers of a service center and hosting a file for the website in a storage unit associated with the one or more servers. . Upon receiving user input from the client device to the service center web browser, streaming interactive video of the web page is transmitted to the client device with substantially no detectable latency. [Selection] Figure 2a


there are shortcomings. One annoyance is his repeated failure to name railroad companies, listing instead the communities they served. For example, he mentions that "Flagler purchased and improved the PalatkaOrmond-Daytona railroad" (p. 49), but he does not specify the details of the transaction. Was this piece of trackage owned by the Jacksonville, Tampa & Key Western, or by some other carrier? At times, the narrative is repetitive, and it lacks a lively style. However, although The Sunshine Economy may not stand as a model for an economic history of an American state, it is to be hoped that subsequent scholars will consider a similar undertaking. They will find much that is useful in this account.


– We consider random walk in a random environment on d-dimensional integer latticeZ with a uniform local drift. The environment is described as a stationary field of random vectors(pk(e)), k, e ∈ Z, |e| = 1 taking values in the standard 2 -dimensional simplex with the support of the law of ∑ |e|=1 epk(e) lying on one side of a certain hyperplane (the so-called non-nestling condition ). We admit that the vectors at different sites may dependent on each other, however their dependence range is finite. The main result of the paper is the law of large numbers for the trajectories of the walk under the probability obtained by averaging the laws of the random walks with respect to the environment (the so-called nnealed probability ). This result is related to the work of Sznitman–Zerner [18] where the law of large numbers has been shown for environments consisting of i.i.d. random vectors and satisfying the so-called Kalikov drift condition.  2003 Éditions scientifiques et médicales Elsevier SAS MSC:primary 60K40; secondary 82D30


Focusing on linguistic and social aspects, this article analyses the poetic language of Antonio Porchia (Conflenti, 1885-Buenos Aires, 1963), Italian immigrant arrived in Buenos Aires in 1902 and author of aphorisms collected in a book titled Voces (1943, 1948 and 1965).


the end of the Cold War, this appraisal has usually concluded that Turkey was sufficiently pivotal that Greek pressure for sanctions to force Turkey to be more forthcoming in regard to Cyprus was resisted. Whether this situation will now change can potentially be important for the future of the Turkish Republic of Northern Cyprus, which was proclaimed in 1983 and has to date been recognized only by Turkey, and to Turkey's broader view of its position in world affairs, which has sometimes been tied to the degree of support it has received regarding Cyprus. Bahcheli, of King's College in Ontario, Canada, looks at the Cyprus problem in a more regional context, but one which also has major international implications and potential consequences for Turkey. Greece is not only a member of NATO but , more importantly today, is also a member of the European Economic Community, which Turkey is seeking to join. Bahcheli traces the steadily deteriorating relations between the two countries since the days of Ataturk and Venizelos despite various a t tempts by their successors in both countries to resolve the numerous issues between them. Among the means Greece has used to pressure Turkey have been opposition to Turkey in the EEC and other European fora, and mobilization of a Greek-American lobby in the U.S. Congress (though both Bahcheli and Bolukbasi note that the latter has had only limited and intermittent effect, despite the view of many Turks that it has been a major influence). Bahcheli's conclusion is optimistic, that the disputes can be resolved, though this reviewer has seen little evidence of that to date, and it could be argued that the waning of the cold war and the growing preoccupation of the members of the EEC with the challenges of eastern Europe can significantly reduce Turkey's influence.


In traditional worldviews, the natural environment was replete with sacred powers. With a holistic worldview, people interacted with nature and sacred manifestations through ritual practices, and organized their lives in spaces suffused with supranormal beings. Nowhere is this more evident than in the religious cultures that developed at sacred mountains. Yet due partly to the sway of the normative analytical model that privileges doctrinal and ideological dimensions of religious phenomena, little attempt has been made to explore the rich relationships between nature and the sacred in the religious cultures of sacred mountains. By examining legendary narratives, rituals, and the landscape of Kôyasan Buddhist monastery in Japan, the paper investigates how elements of nature, in particular land and soil, were infused with symbolic meanings, and played vital roles in the production of a local political space and trans-local religious culture in medieval and early modern periods.


The influence of isotropic in-plane stresses on the fundamental vibration frequencies of thick triangular plates is investigated. Some critical buckling factors are also presented in the paper. Due to the lack of results and importance of this topic, the Rayleigh-Ritz method is applied to solve the governing eigenvalue function based on the Mindlin plate theory. The fundamental frequency parameters for triangular Mindlin plates subject to uniform tensile and compressive stresses with different combinations of free, simply supported, and clamped boundary conditions are determined. The solutions are presented in the form of design charts where the fundamental frequency parameters can easily be read for particular thickness to width ratios (t/b) and in-plane stresses. Since no other vibration solution for thick triangular plate is available, the thin triangular plate solutions obtained by setting the thickness to width ratio to be very small (say t/b = 0.001), where possible, are verified with known solutions from the open literature.


Lakes in Himalayas are one of the preferred tourist destinations of all ages. Their maintenance and usability is of serious concern. The 'Sumendu Lake' popularly known as the 'Mirik Lake' is among the very few most visited tourist destinations of West Bengal. An assessment of its current status and condition holds special relevance for the geographers. Overall, this lake is exhibiting varying degrees of environmental degradation caused by encroachments, eutrophication (from domestic and commercial effluents) and siltation. The high population density ensures that many water bodies are under severe and direct pressure from anthropogenic activities in their catchments. With this aim in mind, the present work is an attempt to decipher the popular perception regarding the degeneration of lake with a futuristic outlook.


The maximum SNR detection can be achieved by selecting the frequency band with the greatest difference of target response compared with the ambient clutter or noise. However, compared with the traditional LFM signal, the optimized cognitive waveform has a narrower bandwidth, so the target resolution obtained after matched filtering will be reduced correspondingly, which will cause difficulties for the later fine recognition task. Target feature in this paper, combined with sparse optimization of high SNR high-resolution cognitive radar waveform design method for the target in the scene, in cognitive radar high SNR radar waveform optimization, on the basis of sparse frequency emission waveform design, with the method of sparse reconstruction recovery goals, can achieve the same resolution with linear frequency modulation signal bandwidth, at the same time as the target signal is sparse form, signal-to-noise ratio was improved greatly, compared with the traditional waveform goals at the same time improve the signal-to-noise ratio and resolution. On the basis of theoretical results, cognitive sparse waveforms are designed for sparse targets with known response functions by combining with actual signals such as finite time and constant envelopment to generate constraints. Simulation results show that this method can obtain high SNR while obtaining high resolution targets.


This work presents for the first time a solution to the 1821 unsolved Sawa Masayoshi's problem, giving an explicit and algebraically exact solution for the symmetric case (particular case b = c, i.e., ABC \equiv right-angled isosceles triangle), see (1.60) and (1.61).
Despite the isosceles triangle restriction is not necessary, in view of the complexity of the explicit algebraic solution for the symmetric case, one can guessing the impossibility of achieving an explicit relationship for the asymmetric case (the more general case: ABC \equiv right-angled scalene triangle). For this case is given a proof of existence and uniqueness of solution and a proof of the impossibility of getting such a relationship, even implicitly, if the sextic equation (2.54) it isn't solvable. Nevertheless, in (2.56) - (2.58) it is shown the way to solve the asymmetric case under the condition that (2.54) be solvable. Furthermore, it is proved that with a slight modification in the final set of variables (F), it is still possible to establish a relation between them, see (2.59) and (2.61), which provides a bridge that connects the primitive relationship by means of numerical methods, for every given right-angled triangle ABC.
And as the attempt to solve Fermat's conjecture (or Fermat's last theorem), culminated more than three centuries later by Andrew Wiles, led to the development of powerful theories of more general scope, the attempt to solve the Masayoshi's problem has led to the development of the Theory of Overlapping Polynomials (TOP), whose application to this problem reveals a great potential that might be extrapolated to other frameworks.


The utility model discloses a direct-current permanent magnet brushed motor testing system, which comprises a control unit, a motor working power supply, a voltage/current testing unit, a load testing module and a no-load testing module, wherein the motor working power supply, the voltage/current testing unit, the load testing module and the no-load testing module are connected with the control unit. The load testing module includes a coupler, a torque sensor, a brake, a brake control unit and a torque testing unit, the coupler, the torque sensor and the brake are sequentially connected with a motor spindle, the brake control unit is connected with the control unit and the brake, and the torque testing unit is connected with the control unit and the torque sensor. The no-load testing module includes a signal detecting unit and a waveform processing unit, the signal detecting unit is connected with a motor, and the waveform processing unit is connected with the signal detecting unit and the control unit. The direct-current permanent magnet brushed motor testing system realizes electromechanical characteristic testing of the motor in a no-load mode by means of disconnection of the coupler, realizes switching the no-load mode to a load mode by means of connection of the coupler, is simple and convenient, saves time and labor, and improves motor testing efficiency.


Despite decades of research and numerous studies, the evidence supporting altitude adaptation for lowlanders who intend to perform at or around sea level is still under debate. In a recent study, Girard and colleagues aimed to complement the general consensus that the "live high-train low" is the most advantageous regimen by adding either normoxic (LHTL) or hypoxic (LHTLH) repeated sprint sessions to improve team-athlete performance. The control group intervention consisted of 14 days "live low-train low" (LLTL) regimen, attending ordinary team training but without added sprint sessions. Both groups with the "live high" and added sprint sessions (LHTL and LHTLH) showed enhanced running performance 5 days and 3 weeks after the intervention. Sprint time was reduced at 5 days post-intervention in both groups, and this reduction was maintained at the 3 weeks post-intervention test in the LHTLH group only. Based on this 3-weeks post-intervention result, the authors suggest that LHTLH confers a sprint performance advantage. Unfortunately, the lack of a fourth intervention group (LLTL + sprint) makes the distinction between the effects of high-altitude residency and sprint exercises on performance difficult. With these performance data as a backdrop, the authors extended their study with descriptive analyses of skeletal muscle molecular adaptations. In summary, a set of gene transcripts associated with adaptations to exercise, including key angiogenic regulator Vegf, and regulators of mitochondrial biogenesis, Pgc-1a and Tfam, were significantly increased in the biopsy taken after the LHTLH intervention compared to the LHTL and LLTL interventions. These changes were suggested to reflect an enhanced skeletal muscle adaptation with the LHTLH regimen. The authors further speculate that these changes were dependent on differences in HIF activation as hif-1a mRNA also was higher in LHTLH group. It should, however, be noted that although the current literature proposes a primarily posttranslational regulation of HIF-1, HIF1a protein was not characterized in this study. Although Hif-1 is often introduced as a mediator of exercise adaptation, the story is likely more complex. Combining and/or comparing information from descriptive human intervention studies and experimental animal models can provide additional information on the role of hypoxia-induced mechanisms for performance and may aid in dissecting global (whole body) hypoxic response mechanisms involving peripheral muscle adaptation. For example, mice harbouring a skeletal muscle-specific deletion of Hif1a performed better in endurance trials and demonstrated several of the features associated with trained muscle, including mitochondrial adaptations. However, a recent study using an inducible global (whole body) deletion of PHD2 in mice (resulting in oxygen-independent Hif activation in multiple organs) exhibited elevated haematocrit, increased skeletal muscle capillarization and enhanced improvement in running time in response to training. These studies highlight the complexity of interpreting hypoxic regulating pathways in exercised and remodelling skeletal muscle. LHTLH and LLTL groups both showed increased protein levels and activity of citrate synthase, an indicator of muscle oxidative capacity, as compared to the LHTL + RSN group. Enhanced CS activity has been shown to be associated with improvements in aerobic performance, and sprint exercise can improve CS activity. Sustained environmental hypoxia as experienced in both LHTL and LHLTH conditions has been associated with an attenuation of oxidative processes. In line with this, a reduced CSA activity was observed in LHTL; however, notably, the repeated sprint intervention under hypoxia seems to have counteracted the detrimental effects of chronic hypoxia (LHTL) on oxidative capacity. This finding is supported by previous human studies showing an augmentation of peripheral adaptations during exercise with reduced oxygen delivery, which was associated with increases in Hif-1 and Pgc-1a activity. From a perspective of optimal performance, the use of hypoxic interventions is controversial and, as suggested in the current studies by Girard and Nunomiya, most likely expand beyond the effects of hypoxia on skeletal muscle tissue to comprise integration of multiple tissue adaptations, including buffering systems as well as ventilatory and cardiovascular responses. The current study utilizing DOI: 10.1111/apha.12989


Criss-cross seam treatment of asphalt pavement in overhaul and medium maintenance engineering is very critical,which influences pavement quality directly.The construction technology is elaborated from the practical construction process.


According to rock character of a certain soft rock tunnel of Chongqing,the model material is made from epoxy resin,polyamide,silicom rubber,firming agent of silicon rubber,quartz grit,powdery barite and gasoline.The physical model test of the unreinforced tunnel and bolt-reinforced tunnel are made in the true triaxial model test machine.By using strain measure technology,the strains of key parts of the surrounding rock and the bolt are measured;according to these data,the variability of the stress of surrounding rock and the variability of the axial force of the bolt are analyzed.The numerical simulation are made with the same boundary condition as the model test;according to these data,the plastic zone,stress field and the deformation of the surrounding rock are studied;the variation of the axial force of the bolt is studied.We compare the variation of stress of the surrounding rock and the variation of the axial force of the bolt of the model test with the numerical simulation and draw the conclusion that the two processes coincide with each other.


The purpose of this study is to identify the relationship between students' views on homework and their learning styles. The study follows a descriptive survey model. It is also an example of descriptive study in relational screening model. Target population is all first, second, third, and fourth year students who are enrolled in Cukurova University Primary School Classroom Teaching Department. The participants are 443 students who volunteered to fill in the data collection forms used in the study. Of the participants, 90 were first year, 103 were second year, 140 were third year, and 110 were fourth year students. 275 of the students participating in the study were female (62.1%) and 168 were male (37.9%). The data were collected through "Homework Attitudes Scale" developed by Gunduz (2005), Kolb's Learning Styles Inventory (LSI) which was first examined for its applicability in Turkey by Askar and Akkoyunlu (1993), "Homework Purpose Scale", "Homework Management Scale" and "Personal Information Form" developed by the researcher. No instruments were used to measure students' academic success levels; their academic success was identified according to the overall mean score obtained from the scores they received from all lessons. Findings show that 141 students (31.8%) preferred assimilating learning style while 133 students (30%) preferred converging learning style. Dominant learning style was found to differ according to grade level and grade point average. The difference in terms of homework attitudes, homework purpose, and homework management scale mean scores was in favour of mostly students who have converging learning style. Besides, there was a significant difference in terms of doing homework on time in favour of students who have converging learning style, and there was a significant difference in terms of coming to class without homework in favour of students who have diverging learning style.


Booklet on Prevention of Obesity on Knowledge Level of Junior High School Students in Yogyakarta City Background: Obesity has turned into a global health issue because it occurs nearly everywhere in the world. Prevention of teenage obesity in Special Province of Yogyakarta (DIY) needs to be done as early as possible, especially in the city of Yogyakarta which has the highest rate of obesity compared to other districts, 14,2% within the 5–12 years age group. Behavioural awareness in maintaining their health can be created through an increase in knowledge, which is expected to decrease the obesity rates in teenagers. Objective : This research aims to determine out the effectiveness using booklet (about prevention of obesity) as a medium to educate health towards the level of knowledge. Methods: This type of research is a quasi-experimental with a pre and post-test. Data on knowledge were obtained from pre and post-test questionnaire. Results: There is a difference in the level of knowledge before and after health education using booklet (p<0,05). Booklet gave an effect towards in the form of increased knowledge. Conclusion: There is a difference in the level of knowledge before and after health education using booklet (p<0,05). Booklet gave an effect towards in the form of increased knowledge.