Recently, we have constructed a new homogeneous cav itation model, which includes various elementary processes in cavitation bubbles on the b asis of a method of moments. We already confirmed that CFD simulation with this model can predict lif t coefficient of a hydrofoil in cavitating water fl ow better than some conventional methods while the tem perature decrease by thermodynamic effect in liquid nitrogen as a cryogenic fluid is underestima ted. In this paper, we re-applied the cavitation mo del to a CFD simulation around the same target, cavitat ing liquid nitrogen flow around NACA16-012 hydrofoil. As a result, the temperature decrease by the thermodynamic effect is fairly well reproduced compared with the previous result when we arranged th model parameter of the growth/shrinkage while a limitation of homogeneous model and that of turbulence model are still indicated.


Software systems can fail when requirement constraints are overlooked or violated. With the increased complexity of software systems, software development has become more reliant on model driven development. The paper advocates a model driven approach to ensure real-time requirement constraints are taken into account prior to the design of a multi-agent system (MAS). The paper presents the synthesis of a real-time metamodel to support requirements analysis of a MAS. The metamodel describes a collection of modelling units and constraints that can be used to identify the real-time requirements of a multi-agent system during the analysis phase. The paper takes the view that the earlier you model real-time requirements in the software development life cycle, the more re- liable and robust the resultant system will be. Furthermore, the more likely it is an ap-propriate balance between competing time requirements will be achieved. The paper also presents a validation of the metamodel in a Call Management MAS application. This provides a preliminary evidence of the coverage and validity of the metamodel presented. © 2017 efficiently interact in real-time to re-plan/reschedule the required tasks in a way that fits unexpected changes in the environment. A gap remains between modelling the MAS requirements and the realisation of the real-time software components required to operationalise real-time constraints of MAS tasks. This research seeks to contribute to bridging this gap. Specifically, it aims at providing a requirements modelling framework to facilitate identifying a sufficient set of activities to identify when a task have failed to meet its real-time constraints. The framework will ensure that tasks that have failed can be distinguished from those that are late but still likely to suc-ceed. The framework will be domain independent. It will depend on two sets of criteria: The first set provides the knowledge to identify the success or failure of the task to meet its real-time constraints. The second set provides the possible set of available behavioural actions. A task taking too long is considered failing when a real-time constraint applies. Receiving the right answer too late becomes the wrong answer [25] . Runtime errors and exception handling in the development phase typically require a different set of tasks to be initiated when an error occurs [58] . If a mission-critical task is taking too long to complete, it can lead to unwanted consequences, e.g. dialling an emergency number then having to wait for an hour for it to ring cannot be regarded as successful. This is different from fault tolerance: "the application service must continue even if parts of the control system have failed" [36] . Fault tolerance focusses on the behaviour of the task after reporting a failure in order to start an alternate task to fulfil the application goals. This research is more concerned with synthesising a reliable and precise analysis process to ensure that the system modeller captures the real-time constraints and the concomitant agent's behaviour.


ABSTRACT This article advocates for a conceptualization of occupational therapy service delivery and intervention for students with sensory integration and processing challenges which improves occupational participation and performance within the educational setting. By offering a full continuum of service delivery options through multi-tiered systems of support, the school-based practitioner can provide services at the appropriate level of programming. Additionally, sensory, regulatory, and relational processes are increasingly recognized as inextricably linked in development and necessary in the provision of services for students with differences in sensory integration and processing. Thus, services for this population must include a multi-tiered approach in offering a complete array of service delivery options, and intervention needs to be inclusive of strategies from three domains: sensory, regulation, and relationship.


In "Context in Children's Speech," J. Cook-Gumperz and J. Gumperz note that the issue of context has always been important in child language studies, since researchers have had to "fill in" context in order to understand the utterances of children and their parents. Cook-Gumperz and Gumperz are concerned with the development of a notion of context that goes considerably beyond context as merely background information. Context is usually a label to index whatever can't be accounted for in linguistic terms in a given communicative act. Cook-Gumperz and Gumperz remove the notion of context from that catch-all category and place it centrally in the process of communication. In this view, speakers actively select aspects of the environment and utilize them as functioning, contributive dimensions of communication. In other words, context is, retrospectively, a consequence of the dynamic process of interaction. Context is used by the participants to serve as part of the meaning of the message in their communications. Context is a rich and powerful concept, and its role in acquisition needs to be investigated in depth ontogenetically. The development of communication in children, and their acquisition of language, require an active role for context. The contextualization process cannot be taken for granted, even to the extent of merely viewing context as an external constraint on acquisition. Context is central, internally, to development, and it is that realization that points to new research directions. The Waterson & Snow volume serves to mark the transition in graduated steps from a research interest in social context as external, 'correctable' sociological variables to one in which social contextualization is the central process in acquisition. Given that important development, we can expect to see more research in language socialization.


This research generally aims to reveal a clear picture of the effect of work discipline on teacher work performance. The research method used is a descriptive method supported by literature studies and by quantitative approaches. The population in this study was 30 respondents from teachers of SMA NEGERI 4 Bandung. Wms data processing results (Weight Means Score) that has been processed obtained the average result of variable score X of 4.27 which belongs to a very high category. As for variable Y obtained an average score of 4.04 which belongs to a very high category. Based on the results of the Normality Test, each variable is obtained that the calculated X2 value of variable X is 7,975 the value of X2 table value is 11,070, it is declared normally distributed, while variable Y value X2 calculates 5,798 the table X2 value is 12,592, it is declared normal distribution. Based on the results of the Correlation Coefficient Test obtained by the price of correlation coefficient (r) variable X to variable Y positive direction of 0.99, it can be concluded that the correlation coefficient between the two variables is at a very strong correlation coefficient level. Based on the results of the calculation of significant tests obtained the price of 1 count of 37.05 and the price of t table of 2,045, the correlation of variable X to variable Y is significant. While the coefficient of variable determination X terhdap variable Y by 98.01%. It can be concluded that the increase and decrease in teacher work performance is determined by the teacher's own work discipline of 98.01%, while the remaining 1.99% is determined by other factors. Based on the calculation result obtained price a and price b of 0.983, so the regression equation that describes the predicted score of variable direction Y based on variable X is Y = 0 + 0.983 X. The difference in the overall statistics test results can be concluded that " There is a Significant Influence between Work Discipline On The Prestassi Work of Teachers SMA NEGERI 4 Bandung ", proven to be true or acceptable.


It has been shown that finding generic Bell-state diagonal-entanglement witnesses for d{sub 1}xd{sub 2}x{center_dot}{center_dot}{center_dot}xd{sub n} systems reduces to linear programming if the feasible region is a polygon by itself, and it can be solved approximately via linear programming if the feasible region is encircled by a polygon. Since solving linear programming for the generic case is difficult, multiqubit, 2xN and 3x3 systems for the special case of generic Bell-state diagonal-entanglement witnesses for some particular choice of parameters have been considered. We obtain the optimal nondecomposable entanglement witness for a 3x3 system for some particular choice of parameters. By proving the optimality of the well-known reduction map and combining it with the optimal and nondecomposable 3x3 Bell-state diagonal-entanglement witnesses (named critical entanglement witnesses) the family of optimal and nondecomposable 3x3 Bell-state diagonal-entanglement witnesses has also been obtained. Using the approximately critical entanglement witnesses, some 3x3 bound entangled states are so detected. So the well-known Choi map as a particular case of the positive map in connection with this witness via Jamiolkowski isomorphism has been considered.


This article reports the results of the analysis of the flow regime in the catchment area of the Mirna River. The effects of the constructed hydrotechnological objects on the water supply of the river, as well as the Mirna river regime change, are analysed. A change in the flow regime is determined by comparing data gathered before and after the construction of the Bolonega dam (1987).


It's of great theoretical and practical importance for universities and colleges strengthen the continuing education of the university students under the new circumstances.In order to carry out education on student party members, firstly,we should settle the problem feasibly on the thought of student party members joining in the Party, secondly, set up and perfect the supervision, appraisal and check-up systems, finally, temper and improve the ability of student party members to bring their role into full play.


Purpose – The purpose of this paper is to analyse the introduction of citizen services in the public libraries in Denmark. The paper focuses on how library staff has perceived the introduction and how the library visitors look at it. The paper further elicits information about differences between library visitors using this service and visitors not using it.Design/methodology/approach – The paper examines the introduction of citizen services in two local libraries. It focuses on staff reactions and perceptions and it also analyses the use and perception of the service in relation to the traditional services. The paper is based on interviews with the involved library staff, citizen service users and administrative staff. The paper is also founded on a survey among library visitors in the two libraries. The survey was conducted as an on‐line and a paper‐based survey.Findings – The major findings of the paper are that the library staff as a whole welcome the new work tasks because they feel that it is of val...


to the full P-V data set, resulting in a zero-pressure volume V0 = 77.24 � 0.17 A 3 , bulk modulus K0 = 159 � 8 GPa and its pressure-derivative K′0 = 4.12 � 0.42 for high-spin FP35 and K0,LS = 72.9 � 1.3 A 3 , K0,LS = 182 � 17 GPa with K′0,LS fixed to 4 for low-spin FP35. The high-spin to low-spin transition occurs at 64 � 3 GPa. Using the spin crossover EOS and Debye sound velocity, we derived the shear (VS) and compressional (VP) velocities for FP35. Comparing our data with previous results on (Mg,Fe)O at similar pressures, we find that the addition of iron decreases both VP and VS, while elevating their ratio (VP/VS). Small amounts (<10%) of low-spin FP35 mixed with silicates could explain moderate reductions in wave speeds near the core mantle boundary (CMB), while a larger amount of FP35 near the CMB would not allow a large structure to maintain neutral buoyancy.


The feeding habits of the bighead croaker Collichthys niveatus were studied using 745 specimens collected by bottom trawl net in the West Sea, Korea, in April and October of 2016, 2017 and 2018. The size of C. niveatus ranged from 4.8 to 16.0 cm in total length. The stomach contents analysis indicated that C. niveatus consumed mainly euphausiids and copepods. C. niveatus consumed mainly euphausiids and copepods in all size classes. The dietary compositions of C. niveatus was not significantly different among size classes (One-way ANOVA, P > 0.05). As body size of C. niveatus increased, the mean weight of prey per stomach (mW/ST) tended to increase.


Pterygium is a common fibrovascular ocular surface lesion of the limbal conjunctiva which has the potential to invade the cornea. Typically, it lies in the palpebral fissure and is wedge shaped. Pterygium usually occurs due to chronic sunlight exposure. It can lead to visual disturbance and even blindness by crossing the visual axis in advanced cases. In this report, an interesting case is presented of an advanced blinding recurrent pterygium treated surgically with the combineduseof conjunctival autograft transplantation (CAT) and amniotic membrane transplantation (AMT).


Analysis of flexural and torsional vibrations for biclamped beams is conducted. The analysis is carried out separately for each plane of vibration. The equations of motion for each case are obtained applying Hamilton' s principle. Eigenvalues for the first three lowest modes are given. Analysis also gives the influence of shear deformations on eigenvalues, for various shape of the cross section. Axial loading also causes change of eigenvalues. Numerical analysis is based on finite element methods.


Adsorption behavior of tannin from aqueous solution by the macroporous polymeric resin NG-8,aminated hypercrosslinked polymeric resin NDA-99 and aminated macroporous polymeric resin NG-9 was studied through static experiments.The empirical Langmuir equation was successfully employed to describe the adsorption process and the adsorption capacities towards tannin increase in the following order:NG-9 NG-8 AH-1.The adsorption rate implied a pseudo-second order kinetic mechanism and the value of rate constant of the tested resins in the following order:NG-8 NG-9 NDA-99.The results showed that the pore size distribution and the tertiary amino group on the polymer played a significant role in tannin adsorption performance.


Tandem's VLSI technology development laboratory shut down its CFC (chlorofluorocarbon) degreaser in December 1990. The author discusses the materials and equipment issues that were considered in developing a non-CFC cleaning process for multichip modules. Tandem's solution is discussed in connection with the choice of a semi-aqueous solvent, the batch-type immersion equipment that was chosen, and environmental concerns.<<ETX>>


Studying driving behavior has been considered an important approach to identifying solutions to increase roadway level of service, reduce roadway traffic crashes, improve vehicle designs, and develop in-vehicle safety devices. The purpose of this research was to get insight into the effect of individual differences on driving behavior and traffic flow characteristics. A method of integrating driving simulators and traffic simulation was developed to investigate the effects of driving behavior on traffic flow. First, a cluster analysis was performed to classify drivers into three categories: aggressive, conservative, and moderate. Second, the driving behavior parameters of the three types of drivers were calibrated for traffic simulation models using the experimental data collected in a driving simulator. Then the effects of driving behavior on traffic flow were analyzed by traffic simulation techniques. The results show that the roadways with aggressive drivers have the highest flow rate but least traffic flow stability. Hence, to maintain roadway level of service and improve traffic safety, it is necessary to develop public training and education campaigns to reach out to aggressive drivers.


Background The prognostic importance of subsyndromal delirium is unknown. Objective To test whether duration of subsyndromal delirium is independently associated with institutionalization. Methods The Confusion Assessment Method for the Intensive Care Unit (CAM‐ICU) was used twice daily to assess for subsyndromal delirium in patients with respiratory failure or shock. Delirium was considered present if the assessment was positive. Subsyndromal delirium was considered present if the assessment was negative but the patient exhibited any CAM‐ICU features. Multivariable regression was used to determine the association between duration of subsyndromal delirium and institutionalization, adjusting for age, education, baseline cognition and disability, comorbidities, severity of illness, delirium, coma, sepsis, and doses of sedatives and opiates. Results Subsyndromal delirium, lasting a median of 3 days, developed in 702 of 821 patients (86%). After adjusting for covariates, duration of subsyndromal delirium was an independent predictor of increased odds of institutionalization (P = .007). This association was greatest in patients with less delirium (P for interaction = .01). Speci fically, of patients who were never delirious, those with 5 days of subsyndromal delirium (upper interquartile range [IQR]) were 4.2 times more likely to be institutionalized than those with 1.5 days of subsyndromal delirium (lower IQR). Conclusions Subsyndromal delirium occurred in most critically ill patients, and its duration was an independent predictor of institutionalization. Routine monitoring of all delirium symptoms may enable detection of full and subsyndromal forms of delirium.


This document defines an integrity security context and a
confidentiality security context suitable for using CBOR Object
Signing and Encryption (COSE) algorithms within Bundle Protocol
Security (BPSec) blocks. A profile of COSE is also defined for BPSec
interoperation.


Describes a new type of optical fiber general purpose interface bus (GPIB) in which the parallel data transmission is actualized by multifrequency parallel signals. The multifrequency signals used as parallel data are generated by a set of sine-wave generators and are detected by a set of bandpass filters. By using the frequency multiplex technique, the multifrequency parallel signals are combined, modulated by square-wave frequency modulation (SWFM) scheme, and then transmitted through the optical fibers. This kind of multifrequency parallel signals have been used as the handshake and management signals on the GPIB bus, which can be transmitted over a distance of 1 km. Eight data lines have also been constructed by using 8 optical fibers.<<ETX>>


In this paper, it is proved that if M is a Γ -near_ring and L is its left operator near_ring, then Re( L ) +=Re( M ),where Re(-) denotes the strongly equiprime radical.


Atrial fibrillation (AF) is a worldwide epidemic that has hit about 33 million people. In clinical studies, the efficacy of antiarrhythmic therapy and catheter ablation in the treatment of AF was compared, and controversial results were obtained.
Objective. To analyze three advanced publications in recent years, which, according to the authors, are of fundamental importance for the choice of radiofrequency catheter ablation as a treatment option for AF.
Results and discussion. In the CABANA study catheter ablation was compared with antiarrhythmic therapy and showed significant improvement in the quality of life. Within 3 years, AF recurrence rate was 69% in the group of antiarrhythmic treatment and 50% in the catheter ablation group. The proportion of patients with non-paroxysmal AF decreased from 57% to 26% with antiarrhythmic treatment and up to 16% with catheter ablation. Among the serious complications in the catheter ablation group were tamponades (0.8%), minor hematomas (2.3%) and pseudoaneurysms (1.1%). Thyroid dysfunction (1.6%) and proarrhythmogenic effect (0.8%) were observed in the group of antiarrhythmic therapy.
In the CASTLE-AF (HF) study, 179 patients were randomly selected for catheter ablation, and 184 for antiarrhythmic therapy. All of them were in NYHA class II, III or IV, had left ventricular ejection fraction 35% or less, and used implantable defibrillator.
In the mean follow-up of 37.8 months, significantly less patients died after catheter ablation (24 [13.4%] versus 46 [25.0%]), and less were hospitalized due to worsening heart failure (37 [20.7%] versus 66 [35.9%]).
ATTEST is the first randomized controlled trial that has demonstrated slowing down of the progression of AF after catheter ablation. Radiofrequency ablation was performed in 128 patients, antiarrhythmic therapy was applied in 127 patients. Within 3 years, the incidence of persistent AF or atrial tachycardia was lower in patients treated with ablation compared with patients on antiarrhythmic therapy (2.4% vs. 17.5%; P = 0.0009).
Conclusions. The expected benefit of catheter ablation of AF in comparison with drug therapy is as follows: increase in the probability of maintaining sinus rhythm, improvement of the quality of life, decrease in the number of hospitalizations and all-cause mortality in patients with heart failure, decrease in fatigue.


Prunioside A, isolated from the methanol extract of Spiraea prunifolia var. Simpliciflora's root, is composed of coumaroyl, monoterpene-type, and glucosyl units. The esterase activity of tannase was used to remove the p-coumaroyl and glucopyranosyl groups. The enzymatically hydrolyzed compound was reacted with various acyl chlorides to synthesize its ester derivatives, which showed the inhibitory effects on NO production in murine machrophage?like RAW 264.7 cells stimulated with lipopolysaccharide and interferon-γ.


Abstract The composition and structure of forest stands in the Tatra National Park were examined using data gathered in 2016 and 2017 from 617 circular sample plots (0.05 ha each). The diameter at breast height of all living trees, standing dead trees, snags, and wind throws was measured along with diameters and lengths of fallen logs within the plot boundaries. Tree height was measured for all living trees within the core (0.01 ha) of the sample plots. Using the obtained data, height-diameter curves were calculated for all major tree species and in the case of spruce, the height-diameter relationships were also calculated separately for each of the three elevation zones (up to 1200 m, between 1200 and 1400 m, above 1400 m). For each elevation zone and park protection zone, we also determined the volumes of live and dead trees. The volume of living trees in the Tatra National Park amounted to 259 m3/ha, which was higher than the volume of dead trees (176 m3/ha). Snags constituted the largest part of the dead wood whilst over 97% of the standing dead trees were spruce Picea abies. Among living trees, the share of spruce ranged from 81% in the low elevation zone to 98% in the middle zone. Other significant species in the lower zone were Abies alba (11%) and Fagus sylvatica (4.5%), while in the middle and upper elevation zones only Sorbus aucuparia occurred in significant numbers. Furthermore, in the lower elevation zone, Fagus sylvatica was the only species displaying significantly higher volumes in the 'strict protection' zone compared to the other park areas. In the 'landscape protection' zone, Picea abies was the most dominant species and the share of other species in the lowest elevation zones calculated based on tree density was smaller than calculated based on tree volume, indicating problems with stand conversion from spruce monoculture to mixed forest.


Waste not, want not! This saying also applies to the yeast. In times of excess this microorganism synthesizes non‐polar lipids, triacylglycerols (TAG) and steryl esters (SE), which serve as energy source and/or as a source of building blocks for the formation of membrane phospholipids when nutriments become limiting. Due to the lack of charged groups substantial amounts of non‐polar lipids cannot be incorporated into cellular membranes, whereas the hydrophobic nature of these molecules also deprives cytosolic localization. Consequently, TAG and SE are stored in specialized compartments known as lipid particles or lipid droplets. TAG synthases and SE synthases which catalyze the final steps in storage lipid formation occur redundantly. Hydrolytic enzymes, TAG lipases and SE hydrolases, initiate the breakdown of storage lipids and make sterols, diacylglycerols, and free fatty acids available for anabolic processes and energy production. In this paper we describe routes of non‐polar lipid metabolism, focus on molecular properties of enzymes involved and discuss regulatory aspects of the respective pathways. The value of the yeast as a eukaryotic model system is advocated.


A numerical investigation of the aerodynamic separation associated with converging–diverging two-dimensional planar micronozzles is reported. The impact of divergent section shapes such as linear, bell, and trumpet, the effect of different back pressure conditions, and the associated flow and separation features are studied. Simulations used the direct simulation Monte Carlo method and are validated with the available experimental data. The lateral separation effect is found to be influenced by the nozzle divergent section shape. The separation performance of micronozzles of different throat sizes indicates the dependence of the exit Kn on separation performance. The bell shape of the divergent section produced higher flow alignment, a thicker subsonic layer, more reduction in exit velocity, and lower separation performance than linear and trumpet shapes. The divergent section with a trumpet shape is preferred for higher species separation performance. The back pressure conditions at the exit of the nozzle are found to play a significant role in the curvature of streamlines and flow characteristics, which may play a vital role in mixture separation performance.


This paper examines G-Town, a Palestinian hip hop crew from Shu'afat Refugee Camp in Jerusalem. G-Town is part of a worldwide cultural phenomenon in which marginalized youths borrow and adapt African-American hip hop culture to their socio-political contexts. Their ability to convey authenticity as rap artists comes from living in a refugee camp, where they are exposed to drugs, violence, and limited opportunities. While G-Town uses rap music as a vehicle to express their opposition to the Israeli occupation, they also use rap music to reclaim their masculinity, especially as Palestinian masculinity has become increasingly emasculated by the practices of the occupation. With Tupac Shakur as their model, the members of G-Town have created for themselves a hyper form of masculinity as a way of coping with the occupation. Rapping has enabled G-Town to emerge as self-appointed leaders of local camp youth, and through their music, they encourage their mainly male audiences to resist the Israeli occupation, while they criticize those who remain passive and whose masculinity thus becomes questionable. Not all their peers, however, are supportive of rap music, and criticize G-Town for having given up practices traditionally associated with the camp's notion of masculinity.


As it was 55 yr ago when the oil town of Taft. Calif. was first booming, water once again is at a premium. Water seems to be the key that will unlock untold millions of barrels of oil from the Midway-Sunset Oil Field and other of the San Joaquin Valley's old fields. The demand for water on the west side has risen from approximately 31,000 bbl/d two yr ago when oil companies began turning to steam injection, to 80,000 bbl/d toady. The West Kern County Water District is pumping to capacity to deliver today's increased output. According to predictions, 380,000 bbl/d of water will be needed in the near future. The next step in securing this water for the west side is expected to be putting up of the additional money by the oil companies to pay for the proposed expansion of the district's water system. When the district begins drawing more heavily on underground water reserves, it may find itself competing with others drawing from the same pool. Two yr ago the water table in the district stood at 55 ft; today it stands at 70 ft.


—Cell-free networking enables full cooperation among distributed access points (APs). This paper focuses on reducing the long-term energy consumption of a cell-free network in the downlink integrated data and energy transfer (IDET) for achiev-ing energy sustainability. The resultant design includes both the AP classification on a large time-scale and the beamforming of the APs on a small time-scale in order to simultaneously satisfy the IDET requirements of data users and energy users. For dealing with binary integer actions (AP classification) and continuous actions (beamforming) together, we innovatively propose a stable double parameterized deep-Q-network (DP-DQN), which can be enhanced by a digital twin (DT) running in the intelligent core processor (ICP) so as to achieve faster and more stable convergence. Therefore, the cell-free network may avoid suffering from performance fluctuation during the training process. The simulation results demonstrate that our DP-DQN exceeds in convergence compared to other benchmarks while guaranteeing an optimal solution.


Background: Background: Philadelphia chromosome (Ph+) is the most common genetic abnormality of B-cell acute lymphoblastic leukemia (B-ALL), and also an independent prognostic high-risk marker. In addition to allogeneic hematopoietic stem cell transplantation, now tyrosine kinase inhibitor (TKI) has greatly improved the prognosis of patients with Ph+ B-cell ALL. Flumatinib is a kind of TKI originally developed in China and has been approved for chronic myeloid leukemia (CML). ABT-199, a selective Bcl-2 inhibitor, was effective in reducing leukemic burden in vitro and in vivo in B-ALL. However, there is no report about the anti-tumor effect of flumatinib in combination with Bcl-2 inhibitor in B-ALL. Aims: Aims: We explore the effect of flumatinib combined with Bcl-2 inhibitor on cell proliferation arrest and apoptosis in SUP-B15 human Ph+ B-cell ALL cells. Methods: Methods: CCK-8 assay was used to analyze the proliferation of SUP-B15 cells treated with flumatinib only, ABT-199 only, combination group, and vehicle control. All groups were treated for 48h at the same time. Apoptosis assay was performed with Annexin V staining following flow cytometry analysis. Expression of the apoptosis-associated gene and protein level was detected by real-time PCR and western blot, respectively. Results: Results: Flumatinib


The relationship between graduate education and professional development is an important issue both theoretically and practically.A survey is reported about the opinions of people who received graduate education at a particular research university,their current professional development and the effects of their education on their career development.According to the results of the analysis,suggestions are made for the improvement of graduate education.


This paper investigates stability problem of DC micro-grid under disturbance. Tracking control based on the sampled H∞ controller is designed for solving such problem. First, it sets up the model o...


The Art Library uses the newspaper cuttings archive to provide her customers with newspaper
articles about art. This archive has the following problems; there is little space left in
the paternoste ...


Introduction: Pulmonary Rehabilitation (PR) is a recommended standard of care in Chronic Obstructive Pulmonary Disease, but to date, there is no consensus of opinion regarding the optimal duration of the interventions. Method: 60 subjects suffering from COPD were recruited after being screened by medical doctors and physiotherapists. A multidisciplinary programme was delivered which consisted of two classes per week for 12weeks. All participants were reviewed again after 4, 8 and at the end of the 12weeks. Exercise capacity using the 6 Minute Walk test was measured and the oxygen saturation was measured before, during and after the test. Dyspnoea scores were taken using the Borg Category Ratio Scale. The St George's respiratory questionnaire (SGRQ) and Hospital Anxiety and Depression scale (HAD) were administered to the participants. The subjects were then enrolled into a one hour of exercise training and was then followed up by one hour of educational talks. Results This study shows that a multidisciplinary programme increases the walking distance reaching statistical significance by the 8 th week of rehabilitation p th week p th week) improves anxiety and depression scores p Conclusion In the present study it has been shown that pulmonary rehabiltiation can help in the amelioration of exercise tolerance and improvement in health related quality of life measures.


The dissertation is aimed to provide an answer to the central question: can, and (if so) how can, an adequate and easy applicable (common) framework of principles and rules be formulated that underlies the fiscal provisions of the EU Member States in order to guarantee a better and more uniform compliance with the rights afforded by the free movement of the economically active person in the EU internal market?


Ta3N5 is a promising semiconductor for solar-driven photocatalytic or photoelectrochemical (PEC) water splitting. However, the lack of in-depth understanding of its intrinsic defect properties limi...


The concept of Effectiveness of Celebrity Endorsement has been explained in different models and theories as a notion related to the characteristics of the celebrity and the management – related perspectives of its use. The impact generated through the effectiveness of celebrity endorsement on endorsed brand is referred as brand evaluation. In addition, Absorption–Addiction Model (McCutcheon, Lynn, Lange, & Houran, 2002) explains how psychological bond between respondents and the respective celebrity is determined via "Celebrity Worship Motives" influences brand evaluation. Accordingly, this paper reviews how celebrity worship motives operate as a mechanism to moderate the relationship between perceived effectiveness of celebrity endorsement and perceived brand evaluation contexts. An extended literature review was followed as the main research instrument by highlighting empirical research gaps postulated by recently held studies. Accordingly, this study aims to propose research propositions to services sector brands in line with the empirical research gaps postulated by recently held studies. Finally, researchers suggest research hypotheses based on the literature reviews and discussions connected to the notion of celebrity worship motives. Paper concluded claiming empirical gaps found in services sector to examine how celebrity worship motives moderates the effectiveness of celebrity endorsement on perceived brand evaluation.


We evaluated the reliability and validity of Wong's Emotional Intelligence Scale (WEIS) – a forced-choice emotional intelligence scale – with a sample of 271 Chinese nurses employed at 2 large hospitals in the Hunan Province of China. The results demonstrated that the WEIS did not fit a 4-factor structure and the scale had acceptable reliability and convergent, discriminant, and predictive validity. Although our results in this study support the practical utility of the WEIS with Chinese nurses, our results suggest the need for further validation of the WEIS.


The drainage of Lake Tai is one of the developed areas in China and its environment is largely destroyed Lake Tai is one of the most nourishing lakes in China The paper, based on the main environmental problems of Lake Tai and applying the integrating techniques of Remote Sensing (RS) and Geographic Information System (GIS), brings forward the pressure of establishing the Environmental Dynamic Monitoring Information System of Lake Tai (EDMISLT) and mainly discusses the technique frame, function and the database of the EDMISLT, at last it emphasizes the issue which should be regarded in the process of establishing the EDMISLT


"No research without trained researchers" has become the mantra of the EU-funded Innovative Medicines Initiative (IMI) education and training projects. However, it is often hard to determine the type of training required at different stages of a scientist's career. The situation is further complicated by the constantly changing environment, e.g. the growth of disruptive technologies, societal expectations of biomedical sciences, the greater need for multi-disciplinary collaborations, and conservative or changing regulatory requirements. This article summarises the experience from a series of five EMTRAIN Public Private Partnership PhD workshops that included both scientific and transferrable skill training. This is followed by an example of a recently developed training programme, including a competency profile, for translational research and medicines development; the C-COMEND teaching programme. The emphasis is on competencies as a new currency for continuing professional development. Finally, this paper describes what we consider to be the next steps required by the scientific community to address solutions to the current training challenges so that society can benefit from the innovations that only science can provide.


The aim of this paper is to present the results of representative population surveys on public perceptions of the shadow economy and actual engagement in shadow economic activities which was conducted in six countries, including Belarus, Estonia, Latvia, Lithuania, Poland and Sweden in May–June 2015. Major results are that the likelihood of being detected by working in the shadow economy labour market is generally seen as low with the exception of Sweden where the majority of the population tends to see this likelihood as rather high. The majority of the survey respondents in all countries do not justify any kind of shadow economy. Only in the case when they have a legal job contract and a part of the wage is paid as an "envelope wage", the justification is somewhat higher. Latvia has the highest share of respondents who have friends or relatives working in the shadow labour market (36 %) and Sweden has the lowest proportion of such population (8 %).


A new styryl-lactone compound, named as leiocarpin A (1), was isolated from Goniothalamus leiocarpus. Its structure and relative configuration were determined by means of spectrum particularly 2D NMR including H-1-H-1 COSY, H-1-C-13 HETCOR, COLOC and NOESY techniques.


Using a first-principles noncollinear wave-function-matching method, we studied the spin-transfer torques (STTs) in CoFe/Mg-B-O/CoFe(001) magnetic tunnel junctions (MTJs), where three different types of B-doped MgO in the spacer are considered, including B atoms replacing Mg atoms (Mg$_3$BO$_4$), B atoms replacing O atoms (Mg$_4$BO$_3$), and B atoms occupying interstitial positions (Mg$_4$BO$_4$) in MgO. A strong asymmetric angular dependence of STT can be obtained both in ballistic CoFe/Mg$_3$BO$_4$ and CoFe/Mg$_4$BO$_4$ based MTJs, whereas a nearly symmetric STT curve is observed in the junctions based on CoFe/Mg$_4$BO$_3$. Furthermore, the asymmetry of the angular dependence of STT can be suppressed significantly by the disorder of B distribution. Such skewness of STTs in the CoFe/Mg-B-O/CoFe MTJs could be attributed to the interfacial resonance states induced by the B diffusion into MgO spacer. The present investigation demonstrates the feasibility of effectively enhancing microwave output power in MgO based spin torque oscillator (STO) by doping the B atoms into MgO spacer.


"Harmonious society" means building a well-off society,raised by the 16th National Party Congress comprehensively as one of the objectives putting forward in.How to understand and grasp the nature of the socialist harmonious society and its building way in China is of great significance.Based on the National Bureau of Statistics establishment of a harmonious society statistical evaluation index system,the author uses the theory of fuzzy statistics to set up a mathematical model of comprehensive evaluation,which can be used to evaluate comprehensively and accurately the degrees of social harmony of a region or a country.


Recovering the 3D shape of the left ventricle from contrast-enhanced bi-planar x-ray image sequences is a challenging task. The inherently sparse and noisy data available for reconstruction and the ill-posed nature of the problem necessitate the incorporation of prior knowledge about the ventricular anatomy. Our novel approach reconstructs the endocardial surface from two projections using a statistical shape model that is learned from high-resolution multi-slice CT data. A non-rigid 2D/3D registration method fits the deformable model to the recorded x-ray images by calculating simulated projections of the model and minimizing the difference between simulated and real projections. The presented algorithm is evaluated based on simulated and real patient data using volumetric and geometric similarity measures. For the first time, bi-planar and CT images of the same patient are used to compare the recovered LV shape with the actual shape.


In this article, I begin to develop Nietzsche's scientific fictionalism in order to make headway toward resolving a central interpretive issue in his epistemology. For Nietzsche knowledge claims are falsifications. Presumably, this is a result of his puzzling view that truths are somehow false. I argue that Nietzsche thinks knowledge claims are falsifications because he embraces a scientific fictionalist view according to which inexact representations, which are false, can also be accurate, or true, and that this position is not inconsistent.


Vision is one of the most important subsystems of an intelligent robot. Without vision, a robot can repeat only one predetermined job sequence where objects are espectcd to be at predetermined places. Moreover, slight disturbances can cause unpredictable circumstances in the robot environment which might prevent the robot from continuing its job scquence. Such a robot system lacks flcxibility and robustness.


13. 5 cm-length disc at 1. 3 m height of 9-years-old deciduous broadleaved timber tree of Liriodendron chinense Sarg. × L. tulipfera L. is simulated on ring width and morphology based on SketchUp. Digital photo of disc imported in SketchUp,is processed by a series of tools to build up original model in combination to physical data. It will further develop configuration for dynamic timing growth,3D printing and quantitative analysis techniques on base of ring width and morphology digitized by SketchUp integrated other software.


This article describes the essence, significance and peculiarities of the institution of parliamentary control in the system of separation of powers. The main direction of parliamentary control is the control over the state budget - a special approach to controlling the expenditure of budget funds, which form the financial basis of the country. Control over the state budget is to ensure socio-economic development, consideration of the State Budget, which is the main financial document, its adoption and control over its implementation. The author describes from his point of view the parliamentary control over the execution of the state budget as the main direction of parliamentary activity, aimed at ensuring the strict observance of budget discipline in the formation and effective use of the state budget by the parliament and its bodies. The article considers the control functions of the Oliy Majlis of the Republic of Uzbekistan on the basis of the Constitution and laws of the Republic of Uzbekistan: аdoption of the State Budget on the proposal of the Cabinet of Ministers and control over its execution, consideration of reports of the Cabinet of Ministers on the results of execution of the state budget by the Legislative Chamber, adoption of relevant decisions, consideration of the report of the Accounts Chamber. The main directions of parliamentary financial control over the state budget are analyzed through the legislative system of the Republic of Uzbekistan. The author puts forward scientific and theoretical and practical ideas for improving the legislation in the field of parliamentary financial control over the state budget.


Radiation hardening is a multiscale phenomenon involving various processes, spanning a wide range of time and dimension. We present a multiscale model for estimating the amount of radiation hardening in pressure vessel steels under light water reactor environments. The model consists of largely two parts: molecular dynamics (MD) simulation and point defect cluster (PDC) model. MD simulations have been applied to investigate the formation of primary damage due to the displacement cascades. The evolution of microstructures has been described by interactions between point defects and their clusters, which are formulated by PDC model. Then, the hardening due to point defect clusters was calculated using a simple dislocation model. Key input into this multiscale model includes neutron spectrum at the inner surface of the reactor pressure vessel steels for the Younggwang nuclear power plant No. 5 (YG 5). The average energy of primary knock-on atoms (PKAs) produced from YG 5 irradiation condition was used as an initial value for the following MD calculation. The combination of MD simulation and PDC model calculation provides a convenient tool in estimating the amount of radiation hardening. The calculation results suggest that the yield strength is increasing with neutron dose, but not significant at this moment.


The vehicle routing problem (VRP) is one of the most interesting NP-Hard problems due to the multitude of applications in the real world. This work tracks a VRP with zone-based prices inwhich each customer belongs to a particular zone, and the goal is to maximize the profit. The particularity of this VRP variant is that the provider needs to determine the prices for each zone and routes for all vehicles. However, depending on the selected zone prices, only a subset of customers will have to be visited. In this work, we propose a novel route generation scheme (RGS) that considers both decisions simultaneously. The RGS is guided by a priority function (PF), which determines the next customer to visit. Since designing efficient PFs manually is a difficult and time-consuming task, hyper-heuristic methods, specifically genetic programming (GP), have been used in this study to generate them automatically. Furthermore, to test the performance of the generated PFs, a genetic algorithm is also used to exploit the RGS to construct the solution. The experimental analysis shows that the evolved heuristics provide reasonable quality solutions quickly, in contrast with the current state-of-the-art. Furthermore, GP produces better results than GA for some problem instances.


The particular significance of the threat of nuclear war in relation to the lifeview of the 270 Midwestern adolescents in our study appears manifest in the high level of awareness and concern a majority show regarding the imminence of nuclear war — its unlimitability, unsurvivability, and probability in their lifetime — and in the significant correlations demonstrated: The most highly threatened are also the more pessimistic about the future — for both the world and themselves, the more sceptical of the efficacy of socio‐political activism, and the more critical of adult stewardship. The intensity of these youngsters' feelings about the threat of nuclear war, their uncertainty about the future, and the depth of their disappointment and disapproval of adults' management of these matters and world affairs may be testimony to a substantial compromising of trust and faith in the parental generation.


Real-time traffic information is a popular element for car navigation system and telematics service, many map website and PND are also trying to provide real-time traffic information to users. The main form of real-time traffic information is Jam Level. Different jam levels are usually shown in different colors in various terminals. But the jam level is not an accurate way to show the traffic state. Different users may have a different feeling about the same congestion status shown to them. A new traffic information representing way was introduced in this paper. The traffic images of roads or intersections are exchanged in real-time between the terminals through the internet. By accessing to the visual information of the traffic, every user can make a decision based on his understanding about the actual traffic, not on the jam level that is translated from average speed by the center side. In this paper, a prototype of traffic image network was presented and the applications were demonstrated based on the prototype.


With the popularity of model-driven methodologies, and the abundance of modelling languages, a major question for a requirements engineer is: which language is suitable for modelling a system under study? We address this question from a semantic point-of-view for big-step modelling languages (BSMLs). BSMLs are a popular class of behavioural modelling languages in which a model can respond to an environmental input by executing multiple, possibly concurrent, transitions. We deconstruct the semantics of a large class of BSMLs into high-level, orthogonal semantic aspects and discuss the relative advantages and disadvantages of the semantic options for each of these aspects to allow a requirements engineer to compare and choose the right BSML. We accompany our presentation with many modelling examples that illustrate the differences between a set of relevant semantic options.


A new anomaly-free gauge model based on an SU(2) direct-productSU(2) direct-productU(1) group is proposed with 32 quarks and leptons. The model permits a dominantly I=0 neutral current, predicts Rapprox. =62/3, explains the $delta$I=1/2 rule, and allows the charmed quark to decay predominantly to nonstrange particles. (AIP)


We present a way to handle exceptions in sequence diagrams. The proposal is inspired by the UML 2 Testing Profiles (U2TP) default mechanism and introduces the use of multiple logical levels of sequence diagrams and what we call dynamic gate matching. The suggested notation distinguishes exception flow from the normal flow of control, creating a visual separation, and providing a way of handling exceptions in both single threaded programs and multi threaded programs. The proposed mechanisms are underpinned by trace semantics


In this article, we examine the contingent effects of signals generated by different types of networks on new ventures' formation of future strategic alliances. We argue that the signaling value of a given tie in reducing adverse selection is more pronounced when another type of tie is lacking. In particular, we suggest that signals associated with (i) a new venture's affiliations with venture capitalists (VCs) that have prominent positions in syndicate networks and (ii) a new venture's prominent position in alliance networks resulting from previous alliances offer redundant benefits. As a result, the positive effect of VC prominence in determining a new venture's future alliance formation diminishes as the new venture's prominence in alliance networks increases. Evidence from biotech alliances between new ventures and established companies provides support for our theory. [ABSTRACT FROM AUTHOR]


This essay focuses attention on the place of theory in empirical research. That is, this essay examines the role of theory in the conduct of empirical research. It is argued that theory and empirical research are critically useful and important to each other as both facilitate the development of each other and they are engaged in an expanding network of relationships. This essay also posits that the indispensability of theory and empirical research to each other becomes glaring when it is realized that a fruitful empirical research cannot be conducted without a theory as a guide, and a theory can only be developed, clarified or reformulated as a product of an empirical research. This means that there is an unbreakable affinity between theory and empirical research. Keywords : Theory, research, empirical research, phenomenon, inquiry


Thermophotovoltaic (TPV) cells convert thermal energy to electricity. Modularity, portability, silent operation, absence of moving parts, reduced air pollution, rapid start‐up, high power densities, potentially high conversion efficiencies, choice of a wide range of heat sources employing fossil fuels, biomass, and even solar radiation are key advantages of TPV cells in comparison with fuel cells, thermionic and thermoelectric convertors, and heat engines. The potential applications of TPV systems include: remote electricity supplies, transportation, co‐generation, electric‐grid independent appliances, and space, aerospace, and military power applications. The range of bandgaps for achieving high conversion efficiencies using low temperature (1000–2000 K) black‐body or selective radiators is in the 0.5–0.75 eV range. Present high efficiency convertors are based on single crystalline materials such as In1−xGaxAs, GaSb, and Ga1−xInxSb. Several polycrystalline thin films such as Hg1−xCdxTe, Sn1−xCd2xTe2, and...


This paper is concerned with the error estimation of a one-step integration method originated from the Lanczos tau method and which is applicable to initial value problems for first order linear ordinary differential equations with polynomial coefficients. The error estimate gives, correctly, the order of the tau approximant being sought.


Abstract Integration of progressive aspects of cultures into development could be a panacea and some culturalarchitects believe that it could spur and increase sustainable and meaningful development. The aim of the presentpaper is to explore efforts of integrating the progressive aspects of culture as well as possibilities of purging theretrogressive ones from the development frameworks. The paper has used a review of literature methodology. Thepaper indicates that integrating progressive aspects of cultures achieves the following: makes development peoplecenteredand people- centric; increases the principle of inclusivity in development; and grounds society into a stateof socialism and communalism. The paper proposes the following aspects of culture to be purged out of developmentagenda: culture of promiscuity; immoral culture of dressing; culture of laziness and dependence syndrome; faultybelief systems; culture of greed and corruption; culture of violence and animosity among countries; and culture ofxenophobia. The paper recommends that Africans undergo a paradigm shift of their mindset to accept integrationof cultures as a panacea in development.


Methods. Patients were randomized to either 6or 12-core transperineal biopsy. All patients underwent prebiopsy evaluation with digital rectal examination (DRE) and transrectal ultrasound (TRUS). Positive DRE was defined as a firm, palpable nodule and/or prostate enlargement. Positive TRUS was defined as a distinct hypoechoic peripheral nodule or extensive hypoechoic band involving the whole peripheral zone. Biopsies were performed on an outpatient basis using a fan technique with 2 puncture sites slightly above the rectum (1 per lobe) under TRUS guidance. Cores were taken from all peripheral areas. In the 12-core technique, additional intermediate cores were obtained. DRE, TRUS, and biopsies were performed by the same urologist.


The aim of this paper is to generalize the endogenous timing game proposed by Hamilton and Slutsky (Games and Economic Behavior, 1990, 2, pp. 29–46) by allowing the payoff or the marginal payoff of a player to become non‐monotonic with respect to the strategy of the opponent. We propose a taxonomy of the subgame‐perfect Nash equilibria based on the characteristics of the payoff functions proposed by Eaton (Canadian Journal of Economics, 2004, 37, pp. 805–29). We determine under which conditions of the initial payoff functions commitment has a social value and when the simultaneous‐move Nash equilibrium is commitment robust and discuss its Pareto efficiency. Jeu a sequences endogenes en presence de non‐monotonicites. Cet article generalise le jeu a sequences endogenes propose par Hamilton et Slutsky (Games and Economic Behavior, 1990, 2, 29–46) en considerant que la fonction de paiement et celle de meilleure reponse de chaque joueur sont non monotones dans la strategie de l'autre joueur. Nous proposons une taxonomie des equilibres de Nash parfaits en sous‐jeux a partir des caracteristiques des fonctions de paiements definies par Eaton (Canadian Journal of Economics, 2004, 37, 805–29). Nous determinons sous quelles conditions sur les fonctions de paiements : un engagement a une valeur sociale; l'equilibre de Nash du jeu simultane est robuste a l'engagement; et cet equilibre est efficace au sens de Pareto.


One indicator of the success of developing and implementing e-learning in a university is user satisfaction, both lecturers and students. E-learning is a learning method to support the process of learning activities carried out online. This research was conducted to analyze the quality of blendeed learning services using the ServQual (Service Quality) and AHP (Analytical Hierarchy Process) methods. The ServQual method is to determine the perceptions and expectations of users of blendeed learning based on student perspectives based on the dimensions of assurance, empathy, responsiveness, reliability, usability and informativeness. To improve the quality of e-learning services, it is necessary to measure service quality using the SERVQUAL (Service Quality) method, to calculate the score gap between the perceived service quality assessment (performance) and the expected service quality. While the AHP (Analytical Hierarchy Process) method is used to determine the weighting value of each variable used in the study. So that efforts to improve the quality of higher education in particular can meet the demands and satisfaction of users.


Fuel is vital both to the production sector and the people's mobility in their economic activities but the government of Indonesia faces difficulties to manage fuel distributions. Indonesia became a net oil importer in 2004, while it imports at market prices, state-owned Pertamina sells petroleum products to consumers at subsidized prices. As of April 2005, the Government owned Pertamina about $2.6 billion in fuel subsidies, putting pressure on the company's cash flow and on its ability to pay for imported petroleum products. This has affected oil supplies to the country, which now faces petroleum shortages. In early September, the Government announced that current subsidy levels can no longer be sustained, and on 1 October, raised fuel prices by an average of 126.6%. As this will have a significant impact on low-income households, the Government will provide direct compensation, giving each household living on or below the poverty line 300,000 rupiahs (about $28) per quarter over the next year. Pertamina desires to handle subsidized fuel oil distribution in Indonesia.Since fuel oil is usually smuggled overseas not the other way around, it causes a serious case such as illegal fuel, shortage of fuel, the accumulate of fuel, etc. For example "Indonesian warship KRI Untung Suropati-872 that patrolled Maluku waters in the eastern part of Indonesia caught tanker KM NMSC-07 which carried 100 tons of fuel oil from China recently" [4]. This case shows that fuel oil distribution in Indonesia has a big problem. An opportunist actor was done a serious case for public demand to get a large profit. Interaction in this fuel oil distribution is very complex, there so many spot and actor which has a different behavior and dynamic character. In this research, we propose fuel oil distribution model, which consists of actors and each of them, can interact at each spot. Interaction between actors is influence by internal factor such as behavior of agent (honest or dishonest) and external factor such as issue (raised fuel price, illegal fuel oil, etc). First, the interaction between spots is modeled by agent-based modeling. Then it proposes a fuel oil distribution in Indonesia without and with an issue about illegal fuel case, shortage of fuel, the accumulate of fuel, etc. Finally, it studies the behavior each actor at fuel oil distribution model and what factor that caused the trouble at fuel oil distribution especially at the city in Indonesia


Euthyphro fails to understand the alternatives, and Socrates proceeds to explain himself through two epagogai. In the first, he introduces the distinction between agent and patient by means of three examples: something carrying and something being carried, something leading and something being led, and something seeing and something being seen. In view of these, he distinguishes between something loving and something being loved.


Key Points Mice with Treg-specific ablation of BATF develop a TH2-dominant disorder. BATF prevents Treg cells from acquiring a TH2 cell–like phenotype. BATF restrains triglyceride metabolism to sustain Treg suppression of TH2 responses. Preserving appropriate function and metabolism in regulatory T (Treg) cells is crucial for controlling immune tolerance and inflammatory responses. Yet how Treg cells coordinate cellular metabolic programs to support their functional specification remains elusive. In this study, we report that BATF couples the TH2-suppressive function and triglyceride (TG) metabolism in Treg cells for controlling allergic airway inflammation and IgE responses. Mice with Treg-specific ablation of BATF developed an inflammatory disorder characterized by TH2-type dominant responses and were predisposed to house dust mite–induced airway inflammation. Loss of BATF enabled Treg cells to acquire TH2 cell–like characteristics. Moreover, BATF-deficient Treg cells displayed elevated levels of cellular TGs, and repressing or elevating TGs, respectively, restored or exacerbated their defects. Mechanistically, TCR/CD28 costimulation enhanced expression and function of BATF, which sustained IRF4 activity to preserve Treg cell functionality. Thus, our studies reveal that BATF links Treg cell functional specification and fitness of cellular TGs to control allergic responses, and suggest that therapeutic targeting of TG metabolism could be used for the treatment of allergic disease.


Case Report We reported 56 years-old woman with skin lesion on the leg since 1,5 years (Fig. 1). This is hard lesion but are bleeding periods and exudation. Occurs big itch of skin lesion and her surroundings. Point biopsy is not entirely diagnostic (Figure 2 4). CK AE1/AE3 (-), S-100 (-), VIM (+) (Fig. 5), CD 68 (+/-). Initial diagnosis: atypical fibro-xanthoma. The skin lesion has been cut-out in its entirety. For a full diagnosis is needed full thickness excision with adequate margins. Suggestions diagnosis: Malignant fibroxystiocytoma, pleomorphic dermal sarcoma. IN ANTICIPATION OF THE BIOPSY. TUMOR ON THE LEG


A peer mentoring processfor part-time faculty not only ensures their teaching skill development, but breaks down colleague isolation and contributes to their institutional commitment.


The purpose of this study was to evaluate the marginal microleakage in Class II with different materials in resin composite restorations cured by using "soft start" and standard polymerization techniques. Two adhesive Class II cavities were prepared in 50 human teeth with enamel in-between. Samples were divided into 5 groups and filled with composite resins, compatible flow resin composites and bonding systems. The ocluso-mesial restorations were cured with standard curing technique, and the ocluso-distal restorations were cured with "soft start" curing technique. After thermocycling, the teeth were immersed in silver nitrate solution and sectioned for leakage evaluation. The results pointed out, after "soft start" and standard curing techniques, that the best marginal behavior in Class II restorations was obtained with Tetric Ceram / Tetric Flow composite resins, then with Filtek Z 250 / Filtek Flow, followed by Admira Admira Flow and Point / Revolution composite materials. The deepest dye penetration was found in cavities with Diamond Lite / Diamond Link composite restorations. No statistically significant difference was found in the tested composite resin restorations, whether treated with "soft start" polymerization or with standard polymerization technique, in regard to marginal micro leakage.


Uncertainties of soil properties are accounted for with a probabilistic approach. Basic ideas of geostatistics are illustrated and discussed by examples from a test site. Easy to use formulas, to combine preknowledge with test results, are presented and an example is given. The application of the probabilistic concepts in deterministic calculations is outlined.


Action is being planned in Scotland to restrict supermarkets promoting unhealthy foods as part of a series of measures aimed at reducing obesity levels.

The Scottish government is also calling on the UK parliament to ban broadcasters advertising foods high in fat, sugar, and salt at times when they can be seen by children. If this is unsuccessful, Scotland will seek such powers to be devolved to the Scottish parliament.

The plans are set out in a consultation document1 …


Abstract We have developed a simple and efficient method for the esterification of various organic acids with C4–C18 alcohols using the 1‐octyl‐3‐methylimidazolium tetrafluoroborate–para‐toluenesulphonic acid (OMIM/BF4–PTSA) couple, without organic solvent, either by classic heating or by microwave irradiation. The utilisation of the OMIM/BF4–PTSA couple presents considerable advantages: high yield, low temperature, short reaction time, isolation of the ester by simple decantation, easy reuse of the catalyst couple.


Trust is emerging as a potentially central aspect leading to IT acceptance. It is especially needed in the case of gaining and later retaining consumers of online vendors. This has been shown by previous research using single dimensional constructs. But trust can also be viewed as a multi-dimensional construct combining specific beliefs (sometimes labeled as trustworthiness) that either directly or through an overall assessment of trust influence relevant behavioral intentions. To show the need to examine trust in a multi-dimensional perspective, this study proposes a three-dimensional scale of trustworthiness dealing with integrity, benevolence, and ability in the unique case of online consumer trust, and then shows the importance of examining the effects of each dimension individually. The data show that trustworthiness and trust should not be regarded as a single construct with a single effect. Rather, different beliefs influence different consumer activity intentions. Window-shopping intentions was affected by the ability-trustworthiness of the vendor, while overall trust in the vendor and its integrity-trustworthiness affected purchase intentions. The importance of differentiating among online customer activities and what dimensions of trustworthiness affect each is discussed.


Eight global and eight local optimization methods were used to calibrate the HBV-TEC hydrological model on the upper Toro river catchment in Costa Rica for four different calibration periods (4, 8, 12 and 16 years). To evaluate their sensitivity to getting trapped in local minima, each method was tested against 50 sets of randomly-generated initial model parameters. All methods were then evaluated in terms of optimization performance and computational cost. Results show a comparable performance among various global and local methods as they highly correlate to one another. Nonetheless, local methods are in general more sensitive to getting trapped in local minima, irrespective of the duration of the calibration period. Performance of the various methods seems to be independent to the total number of model calls, which may vary several orders of magnitude depending on the selected optimization method. The selection of an optimization method is largely influenced by its efficiency and the available computational resources regardless of global or local class. Palabras clave HBV; Calibración; optimización local; optimización global; PCA. Resumen Ocho métodos de optimización global y ocho métodos de optimización local fueron utilizados para calibrar el modelo hidrológico conceptual HBV-TEC en la cuenca alta del río Toro en Costa Rica para cuatro diferentes periodos de calibración (4, 8, 12 y 16 años). Con el propósito de evaluar la sensibilidad de quedar atrapados en mínimos locales, cada método fue probado contra 50 sets de parámetros iniciales generados aleatoriamente. Todos los métodos fueron entonces evaluados en términos del desempeño de optimización y el costo computacional. Los resultados muestran un desempeño comparable entre varios métodos locales y globales dado que se correlacionan fuertemente entre ellos. Sin embargo, los métodos locales son generalmente más sensitivos a quedar atrapados en mínimos locales independientemente de la duración del periodo de calibración. El desempeño de optimización parece ser independiente del número total de llamas del modelo, el cual puede variar varios órdenes de magnitud dependiendo del método de optimización seleccionado. La selección final de un método de optimización está grandemente influenciada por su eficiencia y el nivel de recursos computacionales disponible indistintamente de clase local o global. Introduction Conceptual hydrological models are important tools in operational hydrology, water resources planning and management. These models approximate the general physical mechanisms governing the hydrologic processes through simplified equations, which make them less demanding in terms of model input data and therefore more computationally efficient [1]. Nevertheless, due to their simplified structure, initial values of relevant parameters of conceptual models are usually unknown and must be estimated through calibration using suitable optimization algorithms [2]. In general, optimization methods can be classified as either local or global based on their search strategies [3]. Local methods rely on exploitation, which means that Tecnología en Marcha, Vol. 32, N.° 3, Julio-Setiembre 2019 26 they are carried out by initialization of parameter sets and then iteratively minimizing the objective function; according to a set of deterministic rules. These rules direct the parameter search towards finer solutions. Exploitation may lead to high performance and faster convergence of the optimization method. Nonetheless, the decision on how to sample the following parameter space depends on previous samplings, which can cause the method to getting trapped in multiple local minima or promote premature convergence. Global methods on the other hand, rely on exploration, meaning that the optimization of the objective function is improved by randomly looking into different regions of the parameter space, while keeping the information learned from previous samplings. At the start of the optimization process, global methods largely explore the parameter space to subsequently converge into sub-regions that might contain the global minima based on the response surface type. This is done by a set of deterministic and statistical rules [4]. Estimates from local optimization methods may considerably vary based the choice of starting parameter values [5]. Global methods on the other hand can cope with multiple local minima, discontinuous derivatives and high dimensionality, but are considerably slower than local methods. This is particularly relevant when the evaluation of the cost function is expensive and only a limited number of evaluations are feasible. This somehow makes global methods less attractive in hydrological applications due to its elevated computational cost [6]. Various studies have compared the application of global optimization methods in hydrological modelling using several model-structures and under different climatic conditions [7:9]. Nevertheless, an extensive comparison of local and global methods aimed to identify the pros and cons of each method in hydrological modelling has been mostly left aside. Relevant research questions include: How effective are global and local optimization methods for the calibration of a conceptual hydrological model?, How prone are global and local optimization methods to getting trapped in local minima based on different sets of initial model parameters? Does the duration of the calibration period significantly affect the performance of the various optimization methods and can shorter calibration periods be used confidently? Consequently, this study attempts to answer the abovementioned research questions through the calibration of the HBV-TEC conceptual hydrological model applied to a case study in Costa Rica.


In his Essays on Goethe (1828) Thomas Carlyle concluded, 'In every man's writings the character of the writer must lie recorded ... his opinions, character, personality ... are and must be decipherable in his writings.'1 But four lines later Carlyle confessed he found William Shakespeare stubbornly enigmatic: 'Who knows or can figure what the Man Shakespeare was, by the first, by the twentieth perusal of his works?' Eighty years later in The Impersonal Aspect of Shakespeare's Art, Sidney Lee dismissed any 'critical test whereby we can distinguish Shakespeare's private utterances and opinions ... Where is the critical chemistry which will disentangle, precipitate, isolate his personal views and sentiments?'2 Robert Browning, speaking as Shakespeare, sneered, 'Which of you did I enable Once to slip into my breast There to catalogue and label What I like least, what love best?'3 Citing a multitude of such commentators, in 1991 Samuel Schoenbaum cautioned: 'if we try to get at Shakespeare's opinions by arbitrarily tearing passages from their context, we court hopeless perplexity'. Schoenbaum dubbed those foolhardy enough to try 'personalists' who 'ignore Shakespeare's dependence on written sources, rather than private experiences, for the material of his plays'.4 Despite Schoenbaum's warning, the twenty-first century has seen a remarkable run of intrusive biographies which attribute Shakespeare's opacity to crypto-Catholicism, wariness of tetchy censors, or a calculated self-distancing from the intrigues that roiled Tudor-Stuart England. These range from aggressive (Richard Wilson) to artful (Stephen Greenblatt) to measured (James Shapiro) to bizarre (Clare Asquith).5 The present book is not an attempt at biography. It proceeds from the modest assumption that Shakespeare's plays are more


Purpose – Yam flour (YMF) is an important staple food in the tropics but its utilization is limited by low nutrient and consumer acceptability. The aim of this paper is to investigate the effect of substituting yam flour with grain amaranth on chemical and sensory properties.Design/methodology/approach – YMF and grain amaranth flour (GAF) were prepared on a dry matter basis; GAF was mixed with YMF at ratio 1:3. All flour samples were subjected to chemical (moisture, protein, fat, ash, crude fibre, carbohydrate and minerals) evaluation and sensory evaluation of the stiff gel was conducted by a ten‐member panel consisting of five adult males and five females.Findings – GAF increased the protein content of YMF significantly at p < 0.05 from 1.8 to 9.63 per cent. There was a decrease in carbohydrate content of YAF when substituted with GAF. There was a significant increase (at p < 0.05) in phosphorus and sodium elements when YMF was substituted with GAF. There was no significant difference in acceptability of...


men were of draft age, but only 8.7 million men served in the military. Of those, about 2.2 million men served in Vietnam, while 6.5 million served elsewhere in the world. As the historian Michael S. Foley has observed, the Johnson and Nixon presidencies forced draft-age men to choose either to fight in a war that many considered to be illegal and immoral, to go to jail instead of serving in the military, or find a way to avoid both war and jail. These choices, says Foley, "haunt many of that generation and . . . contribute significantly to the cynicism so many American have come to share about the faithfulness of their government." Reckoning with how and whether to serve in the military was such a wracking decision that many popular magazines, such as Time, Newsweek, U.S. News and World Report, Senior Scholastic, The New Yorker and even Better Homes and Gardens offered advice to draft age men and their families. Draft-age men faced myriad possibilities. They could wait to be drafted and serve as told. They could volunteer for a branch of the military, reserves, National Guard, or ROTC (Reserve Officer Training Corps). They could try to get conscientious objector status, which was very difficult during the Vietnam War era. They could avoid service by trying to get deferments for being married, having children, or being in college or graduate school. They could get or act hurt in order to try to flunk the Selective Service System's physical and psychological examinations to determine fitness for military service. They could elect to go to jail for up to five years. Some men entered the military, but later regretted it and chose to desert. Some men were unable to find deferments or could not face jail. Both of these groups were forced to go into exile and went into hiding all over the world, including underground in the United States. Canada and Sweden were the best places to go in order to avoid risk of arrest or extradition for violation of Selective Service or military laws. Foley feels that draft resisters were to the anti-Vietnam War movement what lunch counter sit-in participants were to the civil rights movement. The draft resistance movement started as early as 1967, predating other events that polarized much of the nation about the war, such as the Tet Offensive, revelations of the atrocities at My Lai, and the invasion of Cambodia. Protesting the Vietnam War: The March on the Pentagon, October 21, 1967. (Photo by Frank Wolfe, courtesy of the Lyndon Baines Johnson Library, serial number: 7052-8.)


This guide is designed to meet the needs of graduate students in the Professional Communication program. Using the Library catalog


Literally the term 'empowerment' implies 'to invest with power'. It is defined as the ability to influence the behaviour of others with or without restraint. Generally it is a socio-political process but particularly it is an individual item of self development. It also means taking control of one's own life. In present context education is seen as the most important element for growth and prosperity of a society, of a state and of a nation. Hence, the education which invests power in somebodyelse for growth and prosperity is called educational empowerment. In other words when an individual or a body of individuals provided with such knowledge which enhances the ability for self development or all-round development needed to lead a meaningful, dignified and civilized way of life is called educational empowerment.


Preface \ Part I The Question Concerning Community: A Status Quaestionis \ 1 From Polis to Community \ 2 The Return to an Original Being-together \ Part II Nancy's Social Ontology \ 3 From Hobbes to Heidegger \ 4 A Co-Existential Analysis of Being-with \ Part III From the Social to the Political \ 5 The Political Dimension of Social Ontology \ 6 Thinking With and About Nancy \ Conclusion \ Epilogue \ Bibliography


ABSTRACT The present study investigated the contribution of cognitive, linguistic, and contextual factors to the narrative production of Norwegian second language learners. We assessed cognitive ability and first and second language proficiency in 66 kindergarten children with Urdu/Punjabi as their first language. Number of children's books in the home and time spent in kindergarten were treated as contextual factors. Oral narration was assessed in Grade 1. A series of fixed-order hierarchical regression analyses displayed a complex relationship among cognitive, linguistic, and contextual factors and various facets of narrative production of young second language learners; nonverbal ability and books in the home predicted the mastering of story (macro)structure, while linguistic (vocabulary and grammar) and both contextual variables predicted microaspects of narrative proficiency. The results suggest that combining home book reading practices, kindergarten attendance, and second language interventions might improve language minority children's narrative production and chances of school success.


The aim of this study is to investigate the sensorless detection method of the pusher plate position for a pulsatile left ventricular assist device (PF-LVAD) based on the driving current waveform. The PF-LVAD is synchronized to the trigger signal of a mock left ventricle, and the experiment is conducted in a mock circulatory system (MCS). The results show that the average error detection ratio of the sensorless detection method is less 1.54%. It is indicated that a sensorless method for detecting the end-systolic position of the pusher plate is reliable. From these results, it is suggested that a sensorless method using the driving current waveform of a PF-LVAD for detecting the end-systolic position of the pusher plate is feasible without additional implanted sensors.


Reading comprehension is critical in life-long learning as well as in the workplace. In this paper, we describe how multidimensional k-means clustering combined with Bloom's Taxonomy can be used to determine positive and negative cognitive skill sets with respect to reading comprehension tasks. This information could be used to inform environments that support students improving their meta-cognitive skills.


This thesis centers around a certain twentieth-century compositionaI device, the method of composition with twelve tones. There are many terms to designate this device, for example: "basic set," "tone-row," "note-series," "serialism," "serial technique," "twelve-note series," "twelve-tone technique" or "twelve-tone method." TI is thesis is a methodical research demonstrating the contemporary conventional way of scientifically and artfully manipulating twelve equal tempered degrees of the chromatic scale to produce a desirable system. In order to arrive at any substantial conclusions, it is necessary to make a critical examination and evaluation of known twelve-tone compositional procedures from as many angles as possible, so as virtually to exhaust every practical and speculative potentiality included in the technique, that is, within the range and limits of our present needs. This examination and evaluation will also involve a comparative investigation of various uses of the device, in order to produce and suggest ideas for further theoretical insights. The ultimate purpose of this thesis is to pinpoint the "hows" and "whys" of Rochberg's use of the twelve equal tones in Sonata-Fantasia.


We describe how color superfluidity is modified in the presence of color-flip and color-orbit fields in the context of ultra-cold atoms, and discuss connections between this problem and that of color superconductivity in quantum chromodynamics. We consider s-wave contact interactions between different colors, and we identify superfluid phases, with five being nodal and one being fully gapped. When our system is described in a mixed color basis, the superfluid order parameter tensor is characterized by six independent components with explicit momentum dependence induced by color-orbit coupling. The nodal superfluid phases are topological in nature, and the low temperature phase diagram of color-flip field versus interaction parameter exhibits a pentacritical point, where all five nodal color superfluid phases converge. These results are in sharp contrast to the case of zero color-flip and color-orbit fields, where the system has perfect U(3) symmetry and possess a superfluid phase that is characterized by fully gapped quasiparticle excitations with a single complex order parameter with no momentum dependence and by inert unpaired fermions representing a non-superfluid component. Furthermore, we analyse the order parameter tensor in a total pseudo-spin basis, investigate its momentum dependence in the singlet, triplet and quintet sectors, and compare the results with the simpler case of spin-1/2 fermions in the presence of spin-flip and spin-orbit fields. Finally, we analyse in detail spectroscopic properties of color superfluids in the presence of color-flip and color-orbit fields, such as the quasiparticle excitation spectrum, momentum distribution, and density of states to help characterize all the encountered topological quantum phases, which can be realized in fermionic isotopes of Lithium, Potassium and Ytterbium atoms with three internal states trapped.


ABSTRACT This article outlines challenges that emerge during the clinical assessment of attention deficit hyperactivity disorder (ADHD) in children. The importance of person-context interactions is highlighted, especially when attempting to formulate the factors that promote and maintain poor psychosocial functioning in children with ADHD. Additionally, a variety of important methodological and age considerations are highlighted. Brief clinical examples are used to illustrate these principles. The review concludes that best practice assessment of ADHD should be systemic and include consideration of child-level difficulties and problematic contexts that are precipitants, perpetuators, and consequences of poor psychosocial functioning. Furthermore, thorough assessment of ADHD should include consideration of other co-occurring psychosocial challenges, consistent with emerging models of psychopathology as a crosscutting phenomenon.


Taking Jinpen Reservoir in Xi'an as a study case,a numerical simulation method for thermal structure of a stratified reservoir was developed and validated against the field data. The development and characteristics of the thermocline under various conditions of short wave radiation and bulk extinction coefficient for short wave radiation was numerically investigated by using a commercially-available software of Fluent. The net total surface heat transfer is positive in spring and summer,while negative in autumn and winter. The long wave radiation mainly contributes to the net total surface heat transfer,while the short one controls the development of the thermocline. The depth of the thermocline increased and the temperature gradient over the thermocline decreased as the bulk extinction coefficient decreased,and the bulk extinction coefficient is positively related to the algae concentration. There was a maximum value of the surface short wave radiation for a certain reservoir,the temperature difference between the top and bottom of the thermocline increased when the short wave radiation was below the maximum radiation,but it decreased when the short wave radiation was beyond the maximum radiation. Moreover,a heat balance and a stable thermocline can't be easily developed under higher short wave radiation.


The passage through borders is an act of faith: cartographer's tools, the language of the stars, the revolving wheel of night must all be sacrificed; the vanishing of reference points must be practised and perfected; the ground must be compacted into a kernel, diamond hard and bright. Only then: the tensing of muscles and the leap...


Transplantation of a fecal microbiota preparation (FMP) is a highly effective therapy for recurrent Clostridium difficile infection (CDI). However, its use is limited by ambiguous regulations and the lack of a standardized product or a common method of administration.

Now, investigators have conducted an industry-funded, multicenter, phase …


In trickle-bed hydrodesulfurization the gas and liquid phases pass concurrent downflow over a fixed bed of catalyst. The hydrotreating of residuum oils at elevated temperatures and pressures in this way has revealed the presence of (undesirable) demetallation reactions taking place in parallel with the desired desulfurization reactions. Organometallic constituents of the oil, primarily vanadium, nickel and iron, react out of the oil and combine with hydrogen sulfide to produce solid deposits of metal sulfides. The deposition of the reaction products occur both inter- and intra-particle. The intra-particle deposits decrease the effective diffusivity of the catalyst causing deactivation by a pore-plugging mechanism. A simple model is proposed to take into consideration catalyst deactivation in residuum hydrotreating by metal sulfides build-up within the pores of the catalyst. The effect of the metal sulfides are considered the dominant feature of the deactivation process based on recent evidence from the literature. The demetallation rates used in the model are typical of current commercial practice. Predictions for catalyst life are compared with commercial data.


Information integration is the needs of the university informationization,Portal provides a unified show platform for information integration which is personalized and interactive.It researches the Portal development technology based on Portal.The core technology of Portal is explained in detail,includes the component and architecture of Portal,Portal internal operating procedures.The detailed development process of Portlet based on RAD development tools is provided.Finally,the development example of information Portal of south China normal university is presented.Study shows that Portal development technology solves the problem of information redundancy and information silos in the university informationization well,provides efficient,uniform,centralized information service platform for campus users,and has a certain reference value to the construction of university information Portal.


moderate stenoses. Colour flow imaging is a new device which displays simultaneously the B-mode image and a colour coded image of blood velocity and blood flow direction. This new technique will be described and some clinical examples will be shown. The advantage of this technique as a supplement to Doppler and B-mode examination will be discussed. Blood velocity measurements in the carotid arteries with Doppler ultrasound are widely used in Norway. This method is sensitive for detection of moderate to severe stenoses. B-mode scanning of the arteries, usually combined with Doppler (Duplex-scanning) is also used to some extent. This combination increases the ability to detect plaques, ulceration and


The poly buffered LOCOS (PBL) technology makes use of a thin silicon film between a thermal silicon oxide layer and a silicon nitride layer. Pits or holes in the silicon film, formed in subsequent process steps, damage the underlying silicon and defeat the device isolation. In this paper we study the influence of deposition temperature, and post-treatment on pit formation in LPCVD silicon films formed from silane and disilane precursors. We show that homogeneously amorphous silicon films (deposition temperature <<550 o C) do not develop device level pits during subsequent processing, in PBL technology


A series of eight novel extended poly(phenylquinoxalines) (PPQs) containing carbonyl, ether and sulphide linking groups were prepared by polycondensation of 4,4'-bis(phenylglyoxalyl-4-phenoxy-4'-benzoyl)diphenyl sulphide, I-D, and 4,4'-bis(phenyl glyoxalyl-4-phenylthio-4'-benzoyl)diphenyl sulphide, 2-D, with four aromatic bis(o-diamines) in m-cresol. The primary objective of this study was to correlate the effect of these linkages on the various properties such as solubility, thermal stability and glass transition temperature of the PPQs. Polymerization of 1-D was carried out in an oil bath maintained at 195-200C whereas polymerization of 2-D was performed at ambient temperature. The polymers prepared were soluble in m-cresol. dimethylsulphoxide, N,N-dimethylacetamide, I-methyl-2-pyrrolidinone and chlorinated hydrocarbon solvents, and formed tough transparent, yellow fingernail-creasable films from chloroform solutions. The inherent viscosities ranged between 0.44 and 0.96 dl g' '. The glass transition temperatures were nearly identical for both systems and ranged from 217-231 'C for polymers prepared from l-D and from 215-233"C for polymers prepared from 2-D. The PPQs having carbonyl and stJlphide linking groups had higher thermal stability in comparison to PPQs having carbonyl, ether and sulphide linkages. The temperature of 10% weight loss for I-D ranged from 484-496 'C in air and 485-516"C in helium whereas those for 2-D ranged from 538-579 XC in air and 522-549 in helium.


Metal-intermetallic lamellar (MIL) composites with different intermetallic phase volume fraction (from 47 to 78 %) obtained by reactive spark plasma sintering (SPS) of Ti and Al foils enclosed in Ti shells were investigated. It was shown that increase of titanium aluminide volume fraction in the composites had no influence on their compressive strength at the loading along the layers. Compressive strength at the aforementioned loading conditions was 775 - 790 MPa. However, at the loading of materials in the direction perpendicular to layers the compressive strength value raised from 655 to 760 MPa with increase of titanium volume fraction in the material.


A complete set of 79 entries comprising of twelve parents, their 66 F1s and one check RLC-92 were evaluated during rabi 2020-21 at two locations i.e., ARS, Dahod, and BTRS, Anand, under two dates of sowing i.e., 2nd fortnight of October and 1st fortnight of November. The present study aimed to investigate the combining ability analysis over environments for seed yield and attributing traits in linseed (Linum usitatissimum L.). Among the all four environments, E1 had higher mean value for seed yield per plant and all other important yield contributing traits by sowing in second fortnight at Dahod conditions best for linseed cultivation. Combining ability analysis revealed importance of both additive and non-additive variances with prime role of non-additive genetic variance for seed yield per plant and its related traits in all environments as well as pooled over environments suggesting heterosis breeding would be more useful for development of superior hybrids if sterility system available. Among the parents; Shekhar, GS 384, KB 9610 and K 29 were good general combiners for seed yield per plant and test weight and capsules per plant. The parent viz., IPI 10, H 45, GS 384 and RLC 133 were good general combiners for earliness. The cross Indira × ILS 264, Gaurav × H 45 and RLC 133 × Shekhar showed higher sca effects for seed yield and test weight. Most of the crosses with high per se performance involved at least one good general combining parent such as Shekhar, GS 384, KB 9610 and K 29 through out for all studied characters.


Background: The loss of smell and taste in COVID-19 patients is now acknowledged as one of the disease's primary symptoms.
Objective: The aim of this study was to investigate the incidence of loss of smell and taste in outpatients and hospitalized patients with SARS-CoV-2 infection that RT-PCR had confirmed.
Methodology: This cross-sectional study was conducted in the in the Novus Molecular Lab, Dhaka between 5 June 2021 and 17 July 2021]. COVID-19 patients were included in this study who become RT-PCR positive in nasopharyngeal and oropharyngeal swabs in a single center. All of them were interviewed by a structured questionnaire over the phone.
Results: Among 200 COVID-19-positive patients smell and taste dysfunction appeared among 75(37.5%) patients. Only smell dysfunction occurred in 57.0% of patients, and taste dysfunction appears in 34.0% patients, and both symptoms were present among 9.0% of patients with or without other symptoms of COVID-19. The smell and taste recovery time was distributed as 63.0% recovered within less than a week, 20.0% within 2 weeks, and 17.0% in 2 weeks.
Conclusion: In conclusion significant number of COVID-19 patients are presented with loss of smell and taste.
Bangladesh Journal of Infectious Diseases June 2021;8(1):32-35


We have studied dynamic friction by impacting a copper plate onto a target consisting of a tapered, annealed, aluminium alloy plug mounted into a matching hole in a stainless steel outer sheath. The velocity of the back surface of the plug was measured using velocity interferometry. Unfortunately it was found that apparently identical configurations gave significantly different velocity profiles. Therefore a series of experiments were conducted in which the manufacturing tolerances were tightened and the assembly procedure was more carefully controlled than previously. Five experiments have been performed at the same impact velocity, (300m/s). Comparing the recent results with those fired previously it has become apparent that work hardening processes in the aluminium alloy near the sliding interface play an important role in the development of frictional forces. It is thought that work hardening generated at those regions of the cone surface in contact with the outer steel component during the assembly p...