RAFT (Ongaro and Ousterhout, 2014) is a distributed protocol used to synchronize some data across a number of replicated servers. How-ever, while the use of RAFT has been well documented for database purposes, storing key-value pairs containing integers or short strings, there has been little research into how RAFT handles replication of large files. In our paper we analyze the performance of the distributed algorithm RAFT under the condition of lossy connection between server and client such as what might be encountered over a mobile network. More specifically we investigate how RAFT implementations handle lost packets or dropped server-client connections when trans-mitting large files such as photos or video. This question is important as the increasing use of cloud photo storage, especially through mobile phone, necessitates the need for better replication protocols for photos and videos. We conduct simulations with the existing RAFT implementation, PySyncObj (Ozinov, 2017), under two modes (abort-if-dropped, and commit-if-dropped) with a variety of network and find that neither mode is satisfactory. Therefore we necessitate the need for a new protocol built on top of RAFT to deal with large files over lossy networks and suggest one such possible protocol.


The present study was carried out to evaluate degradation of heavy metals in effluent waste water samples using microorganisms. The physical and chemical properties of the effluent samples were analyzed using standard methods. The soil sample collected from the heavy metal contaminated sites was subjected to serial dilution and streak-plating methods and six different strains were isolated from the samples. The activity of the isolates for hemolysis was studied on the Blood-Agar plates. The isolated strains were studied for its biochemical and morphological characteristics. The dark-blue colonies were observed by CTAB method, which confirmed the anionic bio surfactant produced by the isolate. The isolates were subjected to other screening tests like emulsification activity and oil displacement technique. These strains were used in the degradation of heavy metals present in the effluent waste water samples. The organism KDM 4 showed better degradation with 93.18% ability in reducing zinc when incubated for 72 hours and 86.36% when incubated for 24 hours in sample 3. The lead reduction was found to be 84.13% by the organism KDM3 when incubated at 37°C for 72 hours incubation. The chromium was reduced by the organism KDM 6 with 87.9% ability when incubated for 72 hours. The organisms had capacity to reduce the heavy metals depending on the factors like time and concentration of inoculum. As the time of incubation increases, more reduction was observed. The least amount of degradation was found in the organism KDM5 with only 27.08%. The percentage of reduction of heavy metals varies from one sample to another sample.


In this paper, we study all possible orders which are less than 1 of transcendental entire solutions of linear difference equations


Venous leg ulcers (VLUs) are a common affliction in an ever ageing population. These wounds are challenging for clinicians to heal, but also affect badly the healthrelated quality of life of patients and their families. This article provides epidemiological information as well as discusses the etiopathogenesis of VLUs. Two VLU cases from Singapore that were managed using a two-layer compression bandage system (UrgoK2®) and a polyacrylate fibre dressing (UrgoClean®) are presented.


The flow around submarine pipelines is represented by a circular cylinder near a horizontal plane wall. The combined effects of Reynolds number (Re = 4000, 6400 and 9200) and gap ratio (S/D = 0.125–2, where S is the gap height between the cylinder bottom and the wall surface, and D is cylinder diameter) on the flow are investigated experimentally using Particle Image Velocimetry (PIV). Detailed velocity vector maps, contours of vorticity, root-mean-square (rms) velocities and Reynolds shear stress are provided. Results show that both the ensemble-averaged and the instantaneous flow fields are primarily dependent on S/D, yet the effects of Re are also obvious over the Re-range considered. Shear layers surrounding the recirculation region behind the cylinder are discussed in terms of the flow physics and vortex formation lengths of large-scale Karman vortices. It is found that the critical gap ratio is about 0.3, higher than which the wake flow is characterized by the alternate Karman-like vortex shedding from the two sides of the cylinder, whereas below which there is no mutual coupling between the two shear layers. Flow structures depending upon the gap ratio and Reynolds number are interpreted with quantitative representations.Copyright © 2010 by ASME


Acknowledgments Introduction by Lewis Fried In the Beginning: American-Jewish Fiction, t880-1930 by David Martin Fine American-Jewish Fiction, 1930-1945 by Lewis Fried American-Jewish Fiction Since 1945 by Bonnie K. Lyons The Greening of American-Jewish Drama by Ellen Schiff American-Jewish Poetry: An Overview by R. Barbara Gitenstein Yiddish Dreams in America by Joseph C. Landis American Yiddish Literary Criticism by Hannah Berliner Fischthal A Question of Tradition: Women Poets in Yiddish by Kathryn Hellerstein Makers of a Modern American-Jewish Theology by Arnold Jacob Wolf Zionist Ideology in America by David Polish American-Jewish Autobiography, 1912 to the Present by Steven J. Rubin Images of America in American-Jewish Fiction by Sanford E. Marovitz Eastern Europe in American-Jewish Writing by Asher Z. Milbauer Shadows of Identity: German-Jewish and American-Jewish Literature--A Comparative Study by Gershon Shaked (Translated by Jeffrey Green) Fiction of the Holocaust by Dorothy Seidman Bilik The Holocaust and Its Historiography: The Major Texts by Saul Friedman American-Jewish Fiction: The Germanic Reception by Sepp L. Tiefenthaler Guide to European Bibliography by Sepp L. Tiefenthaler Selected Reference Materials and Resources


Nowadays a lot of researches are devoted to various methods of activation of water and aqueous solutions. activated water has other specific properties. Under the influence of this water the fermentation activity increases and accumulation of biomass organisms improves, metabolism enhances, extraction properties improve and its antibacterial and antioxidant properties become apparent.one of the methods of water treatment, which belongs to the physical, is an electrochemical activation. It is performed by transmission of electric current through electrodes that immersed in solution. Due to the semipermeable membrane the ion-exchange takes place, which results in change of the properties of the aqueous solution.It is known, that electrochemically activated water has a significant effect on microorganisms. addition of this water to culture media stimulates the generation of microorganisms and increases their activity, which are important parameters for biotechnological processes.Therefore, the aim of the work was to study the influence of electrochemically activated water on the alcohol yeast as industrial micro-organisms in the production of fermentation products, including ethanol.It was found that electrochemically activated water permits to increase the fermentation activity of the alcohol yeast. These results are of practical interest in biotechnology and microbiology in order to control metabolic processes of microorganisms.


Kinetics of background decay in Raman spectra of aqueous solutions of ricin agglutinin in the presence of guanidine chloride were measured. The differences in the kinetics of photobleaching are discussed.


The paper deals with the influence of multipath propagation of transmitted signal, causing additional peaks in the correlation function of the received signals. Also, the multipath adds distortion in the receiving signal and hence an error in determining the exact position of the user equipment. The presence of multipath propagation reduces the signal-to-noise ratio (SNR) of the received signal, leading to an increase in the synchronization error. The characteristics of navigation signals and multipath propagation errors are analyzed. A theoretical study of multipath error envelope are conducted.


A patient was reported who underwent cholecystectomy under the diagnosis of chronic cholecystitis with calculi and adenomyomatosis, but it proved to be an early carcinoma of the gallbladder originating in and limited to the Rokitansky-Aschoff sinus (cyst-like structure). Early carcinoma of the gallbladder in this category is rare and this case report may be the first one in the literature.


We consider functions in the time and the frequency domain, and show how the occurrence of real zeros in the frequency domain is related to the number of zero crossings, overshoot and initial undershoot in the time domain. This leads to simple proofs of known facts for linear time-invariant systems and their generalizations in various directions. In particular, we consider time-delay systems and differential systems of fractional order.


The objective of this study was to reveal the characteristics of amino acid and protein compositions of home-made milk residue from Jiulong yak.Total amino acid content of Jiulong yak milk residue was approximately 36.5 %;the amino acids with relatively high concentration included glutamate,proline,leucine,aspartate and lysine.Essential amino acids account for about 36 % of the total.Electrophoresis showed that the casein was the major protein component of yak milk residue,accounting for about 82 % of the total protein.Slight degradation of yak milk caseins was observed.The result indicated that the chemical composition of Jiulong yak milk residue was similar to yak milk residue of other type.


In this paper, a mechanically steered phase shifter with planar structure is presented for Ka-band satellite user terminals. The proposed phase shifter is composed of a power divider based on ridge gap-waveguide (RGW) and a phase-shifting section based on double-layer groove gap-waveguide (GGW) with a shared rotatable plate. The simulated results show that the phase shifter could achieve 13.6% impedance bandwidth with the reflection coefficient below -15dB. Meanwhile, the insertion losses of all output ports fluctuate around 6 ± 0.5dB and the phase differences remain stably linear over the whole operational bandwidth.


Abstract In order to show the effect of treatment, the change between two repeated psychometric measurements at the individual level should be estimated. The simplest method is to calculate the absolute difference between two measurements. However, measurements obtained in a clinical setting are often influenced by other changes not related to the treatment. One of the typical sources of error is regression to the mean (RTM). Iachina and Bilenberg (2012) propose a new method to adjust to the RTM effect. In this work, we will evaluate the performance of absolute difference method and adjusted method in a simulation study.


To study safety of doing Transthoracic, Patent Ductus Arteriosus Ligation without chest tube insertion. Study Design: Observational, Prospective, Descriptive. Place and Duration: Department of Cardiothoracic Surgery, Postgraduate Medical Institute, Lady Reading Hospital from June 2002 to June 2004. Material and methods: This prospective study was done to study the results of this selective approach in forty five (45) patients, operated by transthoracic approach between June 2002 and June 2004 for patent ductus arteriosus ligation. There were 27 females and 18 males, ranging in age from 06 months to 07 years (mean: 2.3 years) and a weight of 6.0 kg to 22.1 kg (mean 11.3 kg). Patients < 07 years, with no pulmonary pathology, no peroperative pulmonary adhesion, no per operative ruptured ductus arteriosus and with good lung expansion prior to the chest closure were included in this study. Patient more than 07 years of age, with extreme adhesion and those whose patent ductus arteriosus ruptured during dissection were excluded from this study. Parents of the patients were informed about potential risks of this selective approach. Only those patients whose parents had given adequate; informed consent were eligible for this study. Results: There was no mortality. No drain related morbidity Iike pneumothorax, haemothorax or chylothorax occurred. P ostoperatively children had less analgesia, earlier feeds and mobilization. Mothers were not apprehensive about holding or feeding the baby. Consequently there was earlier discharge to home. In addition these children had a more cosmetic scar, and no drain related problems. Conclusion: A selective approach to the use of chest tube in Transthoracic approach for patent ductus arteriosus can be safe, cost effective and patient friendly.


Objective To construct cell mode] of spormatogonial stem cells (SSCs) with Sertoli cells layer,and study the possible mechanism.Methods Germ cells were isolated from testes of KM mice aged 7-8 days,and were en- riched using Percoll grads centrifugation;Sertoli cells treated with mitomycin C were used as feeder cells,the culture medi- um was DMEM supplemented with 5% FBS,co -culture was done at 37℃.Cell growth was observed under inverted phase contrast microscope.Cultured 15 -day cells were treated with haematoxylin-eosin staining (HE) staining and C-kit re- ceptor test.Results①The growth eharacteristics and morphological characteristics of proliferating ceils were accorded with those reported in literatures.②HE staining showed that the size of reproductive cells was even with big round deep- stained nucleus,C-Kit receptor test showed strong positive cell membrane and negative matrix cell,which met the biologi- cal characteristics of SSCs.Conclusion SSCs can grow divide and proliferate in feeder layer without cytokine and primary cultured Sertoli cells.


Objective To prepare simvastatin(SVT)-nicotinic acid(NA) double layer sustained release tablets and evaluate its quality in vitro.Methods The formulation composition of NA sustained release layer and SVT immediate release layer was established by orthogonal experiment and single factor test respectively.The SVT-NA double layer sustained release tablets were then prepared.The relative labeled content of the 2 active drugs in the sustained tablets was determined by HPLC.The release profile of NA in the sustained layer was investigated and the similar factor value(f2) was calculated with the marketed NA sustained tablets as the reference drug.The dissolution of SVT in the immediate release layer was determined according to the related qualifications for SVT tablets in the China Pharmacopoeia Edition(2010).Results The release characteristics of NA in the sustained release layer were similar to those of the marketed NA sustained release tablets and also conformed to the Higuchi equation.The calculated f2 was greater than 75.The cumulative dissolution of SVT in the immediate release layer was above 98% in 30 min and met the requirement of SVT tablets in Chinese Pharmacopoeia.Conclusion The formulation of SVT-NA double layer sustained release tablets is reasonable.The production process is stable and reproducible.The preparation may become a new SVT-NA product.


DOI: 10.5935/abc.20170093 Introduction Variant angina is a form of angina pectoris caused by vasospasm of an epicardic coronary artery that results in myocardial ischemia that might be manifested by transient ST segment elevation on the electrocardiogram.1 Although it usually presents with chest pain, asymptomatic episodes are not rare.2,3 We report a case of an incidental diagnosis of asymptomatic coronary vasospam in a patient with polytrauma.


Abstract : A review of Air Force-sponsored development of a 12,000 RPM superconducting generator is presented. Results are given for recent critical component tests including stator coils and four coil rotor assembly. A brief discussion of potential future work in high power superconducting generators is given. Superconducting generators with specific weights of less than 0.1 lb/kva in the multimegawatt class can be anticipated.


Although many acknowledge that the available metrics for OPO performance are flawed, they cannot be optimized with currently available data. In this manuscript, we propose a simple, feasible, and comprehensive system for collecting the data necessary for research, regulation, and quality improvement of the organ donation pathway. This article is protected by copyright. All rights reserved.


This article employs cultural Marxist and feminist approaches to assess the relationship between the nonpolicing and policing of class and gender relations during the Progressive Era in Eugene, Oregon, USA. A selective review of the literature on the history of policing prefaces an outline of local history in Eugene. I describe the rationalization of the Eugene Police Department during the Progressive Era. I then ask why the social harm caused by the rise of lumber capitalism (e.g. occupational hazards, disease, injuries and fatalities) did not attract the scrutiny of the newly rationalized police. Applying a similar logic to patriarchal relations, I question why domestic violence and prostitution were so passively policed. Having established some of the political parameters of policing by exploring nonpolicing, I examine those forms of "disorder" which served as major policing foci: labour radicalism, the unemployed and vice.


State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Center for Magnetic Resonance, Wuhan Institute of Physics and Mathematics, The Chinese Academy of Sciences, Wuhan 430071, China, Institute of Atomic and Molecular Sciences, Academia Sinica, P.O. Box 23-166, Taipei 106, Taiwan, and State Key Laboratory of Physical Chemistry of Solid Surface & Center for Theoretical Chemistry, College of Chemistry and Chemical Engineering, Xiamen Uni Versity, Xiamen 361005, China


The dendritic processes and terminals of the abdominal muscle receptor organ of the lobster have been studied with the electron microscope. In both the "fast" and "slow" adapting components of the muscle receptor organ, dendritic processes ramify within the body of the stretch muscle in a zone of "relative muscle exclusion," where the continuity of the muscle bundle is interrupted by a zone of connective tissue. The cell bodies and larger dendritic processes are ensheathed in alternate layers of connective tissue and Schwann cells, but the smallest dendritic twigs are entirely divested of their Schwann cell envelope. The membrane of the dendritic terminations is intimately applied to either connective tissue of the zone of relative muscle exclusion or to the sarcolemma of the stretch muscle. This apposition is interpreted as morphological specialization for transduction or mechanoelectric conversion. It is suggested that these two types of dendritic terminals may represent two distinct sites for transduction and may also mediate different modalities of input.


Question: A 54-year-old woman presented with diffuse, crampy, episodic abdominal pain present for several years but recently worsening. There was occasional localization to the right upper quadrant and it was exacerbated with eating. She had nausea without emesis, no change in bowel habits, and no improvement with bowel movements. She denied dyspnea and lower extremity edema. Her history includes sulfa-induced hepatitis in 1987 at which time a percutaneous biopsy was performed. She recovered fully and had no other history of liver injury. She presented with normal vital signs. Examination elicited a soft, diffusely tender, minimally distended abdomen without evidence of ascites. Bowel sounds were hyperactive, and a bruit was auscultated over the right upper quadrant. She had no jaundice or scleral icterus. There was no jugular venous distension, extra heart sounds, or lower extremity edema. Lungs were clear to auscultation. Laboratory investigation including complete blood count, lipase, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, and electrolytes were normal. Total bilirubin was 2.6 mg/dL, of which 2.0 mg/dL was unconjugated. Abdominal computed tomography obtained in urgent care (Figure A) showed a 4.5 3.2 5.3-cm, contrast-enhanced lesion in the periphery of the right hepatic lobe (arrow). Abdominal magnetic resonance imaging (MRI) and ultrasonography were performed. In T2-weighted sequencing (Figure B), MRI demonstrated contrast enhancement of hepatic artery (arrows) and vascular mass (arrowhead) in liver segment VIII. The celiac axis and hepatic artery were noted to be dilated to the same size as the common iliac arteries. T1 sequencing (Figure C) showed a 3.7 2.6-cm vascular mass in segment VII (arrow) and enhancement of the portal vein (arrowhead) during the arterial phase. Ultrasonography confirmed the vascular mass. There was hepatofugal flow in the portal vein. The liver echogenicity and echotexture were normal. The common bile duct was 4 mm. What is the diagnosis? Look on page 1165 for the answer and see the GASTROENTEROLOGY web site (www.gastrojournal.org) for more information on submitting your favorite image to Clinical Challenges and Images in GI.


Objective: To observe the changes of serum D-dimer levels of systemic inflammatory response syndrome(SIRS) patients in ICU in different time,to compare the D-dimer level between thrombosis patients and non-thrombosis patients,and to explore the related factors to D-dimer level.Methods: Blood routine examination,CRP,D-dimer levels and blood clotting of all 162 cases in ICU were detected every six hours within five successive days.The independent variables such as age,gender,baseline of heart rate,respiration rate,body temperature,oxygen index and average of WBC count,CRP,SIRS status,sepsis status,primary disease,the anticoagulant or hemostatic agents,and the average of D-dimer as the dependent variable were input into computer to build the multiple linear regression equation by ENTER method.Results: Within 72 hours,the D-dimer level of all patients reached to the peak before 30 hours and fell to the valley in 60-66 hours except for the patients with non-thrombosis diseases.The D-dimer level curve of non-thrombosis disease patients had greater fluctuation than thrombosis disease patients and had a rebounded descending branch with multiple peaks and valleys after 72 hours.Complex lesions group had higher peak and average values and a longer descending branch than single disease group.The highest peak value appeared in thrombosis disease-based patients and greatest average value appeared in non-thrombosis diseases group.The variables of primary disease,sepsis status,medicines used,average of ALT,WBC count and CRP were closely related to D-dimmer,and the average of CRP was the closest related factor.Conclusion: D-dimer levels of non-thrombosis patients are different from thrombosis disease-based patients in the peak,valley,and average values,fluctuation extent,and the time come back to normal.The D-dimer levels in patients with SIRS are mainly affected by the inflammatory state,the medicines used,organ function and the primary disease.Inflammatory is most likely to lead to elevate the levels of D-dimer in patients with non-thrombosis combined diseases.


It is shown that the spectrum of the reflected wave is transformed as a result of the efficient generation of higher surface wave harmonics in the backward direction from the contact zone. Inversion of the spectrum of a nonlinearly reflected wave is observed under the conditions of weak linear reflection (at an interface between media with similar linear properties)


English Abstract In October 2006, Massimo Gentili-Tedeschi, President of the International Association of Music Libraries (IAML) and Ruth Hellen, head of IAML Outreach, toured music libraries and collections in Armenia and met with librarians and music scholars to discuss the state of the Armenian music libraries. They also met with the Minister of Culture and Youth, Mrs. Hasmik Poghosyan, and made recommendations to her for improvement of the collections and access. In addition, they spoke with her about the actions IAML would be willing to take to support the Armenian collections. French Abstract En octobre 2006, Massimo Gentili-Tedeschi, President de l'Association internationale des bibliotheques, archives et centres de documentation musicaux (AIBM) et Ruth Hellen, directrice de la branche Outreach de l'AIBM (concernant les bibliotheques defavorisees), ont visite des bibliotheques musicales et leurs collections en Armenie. Ils ont pu y rencontrer des bibliothecaires et des chercheurs en musique afin de discuter de l'etat actuel des bibliotheques musicales. Leur rencontre avec le Ministere de la culture et de la jeunesse, Mme Hasmik Poghosyan leur a permis de lui transmettre des conseils pour faire evoluer les collections et leur acces, et d'exprimer les actions que l'AIBM souhaiterait mettre en oeuvre afin de soutenir les collections musicales en Armenie. German Abstract Massimo Gentili-Tedeschi, der damalige Prasident von IAML, und Ruth Hellen, die damalige Vorsitzende von IAML Outreach, haben im Oktober 2006 Musik- und andere Bibliotheken in Armenien besucht. Sie haben dort Bibliothekare und Musikstudenten getroffen und mit ihnen uber die Situation armenischer Musik bibliotheken gesprochen. Bei einem Treffen mit Hasmik Poghosyan, der Ministerin fur Jugend und Kultur, konnten sie Vorschlage zur Erweiterung der Sammlungen und der Verbesserung von deren Zuganglichkeit machen. Ausserdem erlauterten sie ihr, wo IAML Moglichkeiten sieht, armenische Bibliotheken zu unterstutzen. Massimo Gentili-Tedeschi, the President of the International Association of Music Libraries, and I were invited by two Armenian colleagues to visit their libraries and give advice on development. We set off on 9 October 2006 for a trip into the unknown. There are a few well-known facts about the country: they have many ancient manuscripts, Mount Ararat was formerly in Armenia, Khachaturian was Armenian, and there are many ancient churches; Armenia has its own language and alphabet unlike any other. Once we arrived, we were met by our friends Gulo Nahatakyan, Director of the Armenian Musicological Library, and Ruzan Tonoyan, Director of the National Children's Library. They had prepared a full and varied programme for us: Visits * Armenian Musicological Library (Tuesday, Friday) * Yerevan Komitas State Conservatory Library (Tuesday) * Tchaikovsky Music School (Tuesday) * National Children's Library (Wednesday, Saturday) * City Library, Av. Isahakian (unofficial visit: Thursday) * National Library, including the music division (Thursday) Meetings * We spoke at the Librarians' Day hosted by the Minister of Culture and Youth * We had a private meeting with the Minister of Culture and Youth, Mrs. Hasmik Poghosyan (Tuesday) * We had a meeting with the Head of National Library, Mr. David Sargisyan (Thursday) * We participated in a round table with heads of institutions and intellectuals (Saturday) Our official visits began with the Musicological Library, which is used by everyone interested in music, from professional musicians and researchers to school children. The library is government funded but can raise extra money, so members pay $1 to join. There are 33 staff; the library receives legal deposit material via the National Library, but the acquisitions budget is minimal. …


Objective To observe rehabilitation effect of Seroxat combined with emotional care with traditional Chinese medicine on stroke patients with depression. Methods 108 stroke patients with depression were randomly divided into two groups. 54 cases in control group were given system rehabilitation and general care. 54 patients in treatment group were treated by Seroxat combined with emotional care with traditional Chinese medicine on the basis of control group treatment. The effect was assessed after four weeks of treatment. SDS,barthel index,LSIA,rehabilitation effect and patient satisfaction rate were observed. Results SDS,barthel index and LSIA after treatment were improved as compared with those before treatment in two groups( P 0. 05). SDS,barthel index and LSIA in treatment group were superior to those in control group after treatment( P 0. 05). Patient satisfaction rate in treatment group was obviously higher than that in control group( P 0. 01). Conclusion Seroxat combined with emotional care with traditional Chinese medicine on stroke patients with depression can significantly improve the rehabilitation of patients with post- stroke depression,improve patient satisfaction rate.


The paper presents actual results of the research conducted as part of a field pilot project which consisted in interpretation of minifrac test data and evaluation of the efficiency of the scientific and technical supervision of fracking operations. The research program involved 11 wells targeting Devonian terrigenous reservoirs. Minifrac tests in one perforation interval were performed only in seven wells, that is approximately in 64% of total well count. A reliable fracture closure estimate was obtained only in six wells (55%), beginning of pseudoradial flow was observed only in one well out of 11 wells (9%). Hence, conventional minifrac tests should be supplemented with other diagnostic injection tests. Analysis of the performance of hydraulic fracturing operations conducted according to this pilot project plan indicates that fracture modelling, and scientific and technical supervision of fracking operations performed by Hydrofrac Research Laboratory of Institute TatNIPIneft Tatneft PJSC have yielded beneficial effects, namely 1.44 times increase in oil production rates.


The paper analyzed business efficiency (productivity, economy and
 profitability) and business indicators (liquidity, solvency and
 indebtedness) of PE ?National park Kopaonik?. The goal of the research is to
 identify their values, with the purpose of determining the situation and
 recognizing opportunities for possible improvement of certain segments in
 the business of the analyzed PE. The subject of the research is the
 financial reports of PE ?National park Kopaonik?, and the data generated
 from them, based on which indicators of business success were determined.


In the study area farmers have adopt partially modern technology i.e. drip irrigation facility, HYV seeds material, sugarcane, fruits, vegetables, food grain and other crops, increasing uses of composting biomass, machineries, improved plantation technology and micro irrigation systems, available for nearby village inputs (seeds, fertilizers, insecticides, cattle feeds and veterinary services), agricultural labour, bullock power, crop loans, electricity, irrigation, dairy centers and processing units, nearby sugar factory, good network of transports and markets, good communication facilities, agricultural advisory centers etc are available in the study area. Therefore, recently agricultural activities are positively increasing on the day by day. Mostly, eastern part of the study area is concentrate in the rice crop because of these areas situated in the hilly and heavy rainfall. Only Akole circle have leading all crops (various seasons) are grown and needs for market demanding crop. About 80 percent population depends directly upon land middle and eastern part of the Akole tahsil. The area under Soya bean cultivation in the tahsil is about 4,607 hectares on 6.33% in 2010-11.The objective of the study is to study Soya bean distribution and to study in changes 10 years cultivation (Soya bean crop).


The literature of contemporary Portugal is scarcely known in the United States, and an account of Joaquim Pago d'Arcos, one of the leading Lusitanian writers of today, should therefore begin with a recapitulation of recent Portuguese literary history. Julio Dantas, now some seventy-six years old, is the grand old man of Portuguese letters. His national consecration as the President of the Portuguese Academy of Letters is complemented by the international fame which he owes chiefly to his one-act play in verse A ceia dos cardeais (The Dinner of the Cardinals), which has been played in many countries. Three old cardinals-one Spanish, one French, and one Portuguese-while supping in the Vatican recall their youthful love-life before they entered the Church, a step they took because of unhappy sentimental experiences. While the literary elegance of Julio Dantas is respected, he is generally regarded as old-fashioned and has little influence on younger writers; he was the dominant figure during the first decade of this century. A greater influence on younger writers is Aquilino Ribeiro, who achieved great fame immediately after World War I. A novelist from the province of Beira Alta, his first stories such as Terras do demo were regional in character, but his later novels like Mdnica describe life in Lisbon. His style is original and powerful. Ideo ogically he is characterized by a mild anti-Catholicism reminiscent of that of Anatole France, who may indeed have influenced him while he was exiled in France during his youth. Politically, he is not associated with the present regime of Dr. Oliveira Salazar. Around 1927 a literary movement began in the university city of Coimbra; it became known as Presenga after the name of the review which was the organ of the group. It cultivated a modernistic type of poetry, and is best represented by Jos6 R6gio, author of Poemas de Deus e do diabo, who teaches in the town of P6rto Alegre, near the Spanish border. When it is recalled that the Portuguese regard themselves as a race of poets, the fame of Jos6 R6gio will be easily understood. He has also written some symbolical novels, such as 0 principe com orelhas de burro. One of the best-known novels in Portugal is A selva by Ferreira de Castro, who describes in it the Amazon valley where he lived as a youth. This exotic story has been translated into some twenty languages. A decade ago, one of the leading literary figures was Miguel Torga, whose poetry was widely appreciated, but whose novels were less successful. However, he wrote gripping short stories, and his Didrio, of which several volumes have appeared, has been followed with wide interest.


Objective To investigate the clinical effects of precise sequential intervention therapy after primary liver cancer hepatectomy.Methods 207 cases of patients underwent primary liver cancer hepatectomy from 2005 to 2010 in our hospital from 2005 to 2010 were investigated,81 cases were treated with conventional sequential intervention(conventional sequential intervention group),126 cases were treated with precise sequential intervention(precise sequential intervention group).The clinical effect of the two groups were compared.Results Statistical analysis showed that there were no significant differences in the age,operating time,intraoperatie blood loss,perioperative blood transfusion and complications between the two groups(P 0.05).Serum AFP level significantly decreased in the two groups after intervention therapy in 6 months and 12 months(P 0.05).The precise sequential intervention group showed a well tolerance on the intervention treatment,compared with before treatment,there were no significant differences in ALT,ALB and Child-Pugh scores(P 0.05).The tumor recurrence rates and the survival rates of 1,2,3 years of the precise sequential therapy group were 16.67%,22.34%,26.76% and 87.30%,84.26%,78.87%,which of the conventional sequential intervention group were 30.86%,36.88%,47.82% and 76.54%,72.34%,60.87% respectively,the differences were statistically significant(P 0.05).Conclusion Adopting precise sequential intervention therapy after primary liver cancer hepatectomy can protection liver function maximumly on the basis of control tumor recurrence,which can improve the survival rate of patients.


With turbine inlet gas temperatures ever increasing,the turbine blade-surface cooling problem of modern high-performance gas turbo-engines has received growing and unremitting attention. Among numerous cooling technologies,air-film cooling enjoys a conspicuous edge and relatively brilliant prospects for engineering applications. A survey of the recent research findings concerning the air-film cooling technologies used on gas turbine blades was given along with a description of the air-film cooling theory. Summarized were the advances in the study of air-film cooling technologies for blade end walls,tips,as well as leading and trailing edges,and the research results on the flow coefficient of air-film holes. Various factors influencing the air-film cooling effectiveness and their effects on the aerodynamic losses were expounded. Finally,it should be noted that a complex cooling mode combining the air-film cooling with other blade cooling technologies represents the development trend of the technologies under discussion in the near future.


I. MOTIVATION The design of self-organized network architecture requires an efficient tradeoff of robustness and complexity. The resilience of existent proposals and consequently the performance of the routing protocols are strongly related to the complexity of deployed addressing structure. Tree-like structures [1], [2], for example, lead to simple manageable spaces. Nevertheless, they have low route selection flexibility and poor resilience to mobility. Their low complexity is obtained at the cost of some loss of robustness. More complex structures like multidimensional Cartesian spaces are robust to mobility but introduce complexity to the management of the addressing and location space. Due to the complexity involved with a dynamic multidimensional partitioning and management, existing scalable location service approaches [3], [4] are inherently dependent on the spatial distribution of nodes in the topology. They associate nodes to geographic positions in the space which requires the presence of at least one node near the mapped geographic position to play the role of its location server (see Fig. 1). This cannot be guaranteed in a SON because of its variable nature, in time and in space. Topology changes imply that the network needs to be periodically checked in order to accordingly update the associated location servers. The selection of this servers is strongly correlated to their physical coordinates, which introduces some loss of freedom in the indirect location service and extra overhead. This may be prohibitive in many dynamic networks. To overcome the abovementioned issues, our novel architecture Twins performs position-based routing in a multidimensional space, and assures an easily-managed one-dimensional location service.


with the diversified forms of investment and development of diversified tourisms, the rural tourist attractions are built continuously and the tourism aesthetic taste and tourist interest trend are gradually improved. For the overall demand of adapting and developing the rural tourism economy and meet the diversified requirements of different tourists, it is required to deeply research the investment risk and investment environment of the rural tourism, so as to improve the construction of rural tourism facilities and the overall reception. In this paper, starting from the characteristics and reception form of rural tourism, the author evaluates the risks brought by the natural, social and economic environments of the rural hotels and briefly researches the measures taken to prevent and avoid the rural hotel investment


Arguments for the 'Death of Cinema" hold that film's realist destiny has been betrayed by digital technologies. Arguments for the 'Post medium Condition' hold, against the medium-specificity of Greenberg and after de Duve's art made of 'n'importe quoi', that medium no longer matters. In papers on colour separation and management, the temporalities of film and electronic frames, optical construction of volume and chip design, I argue that the material matters more than ever, but that crude binaries do not help understand the dialectic of standardization and divergence characteristic of contemporary mediation. This is especially true of the glass technologies that are key to the history of projection and of digital networks.


This study investigated the effects of the inclusion of Mauritia flexuosa fruit pulp in the diet on the growth performance, economic benefit, muscle composition, total contents of carotenoids and flavonoids, chromaticity parameters, total antioxidant capacity, and lipid peroxidation in the hepatopancreas and muscle of the juvenile shrimp Litopenaeus vannamei (weighing 1.26 ± 0.023 g). Five diets (37% protein, 10% lipid) consisting of 0 (control), 1.25%, 2.50%, 5.00% and 10.00% (w/w) M. flexuosa fruit pulp were formulated and provided to the shrimps (n = 50 per tank, treatments in triplicate) for 31 days. Results showed that there were no significant differences between the treatments in terms of the growth capacity, chromaticity parameters, muscle composition and total flavonoid content of shrimps (p > .05). However, the carotenoid content in the muscle and hepatopancreas of the shrimps was significantly increased due to the dietary carotenoids present in M. flexuosa fruit pulp (p < .05). This increase in the carotenoid content directly favoured the increase in the antioxidant capacity in the hepatopancreas and muscle of the shrimps (R² = 0.99 and R² = 0.97 respectively; p < .05). There was also a direct relationship between the carotenoid content and the decrease in lipid peroxidation in the hepatopancreas (R² = 0.90; p < .05). The feed cost kg⁻¹ in terms of weight gain and protein production decreased with the inclusion of high levels of M. flexuosa fruit pulp, reaching 8.11% and 18.76% of cost reduction, respectively, with the addition of 5.00% of M. flexuosa fruit pulp. Therefore, the inclusion of M. flexuosa fruit pulp in the diets of shrimp can increase the carotenoid content and the antioxidant capacity in the hepatopancreas and muscle, reduce lipid peroxidation in the hepatopancreas, and probably provide economic benefits for the rearing of juvenile shrimps.


In this essay, I investigate how Korean Children's Choirs that toured the United States in the 1950s and 1960s helped rewrite America's relationship with Korea and Asia more broadly. I situate the choristers within the context of transnational adoption to explore the political stakes of the Korean child during the early Cold War. On the heels of the costly Korean War, the young performers represented the democratic possibilities of Korea, thereby justifying US intervention, past and present. For the South Korean government, the choirs were among several carefully crafted cultural productions sent to the United States in an attempt to replace existing conceptions of an impoverished Korea with images of resiliency and capability—critical attributes of a nation seeking sovereignty. Yet while the political agendas of each government remained clear, the children's choirs also set in motion interpersonal relationships that tied Americans to Koreans in new ways. For the first time on a large scale, Americans saw Korean children in an American context, a juxtaposition that deepened sentimental connections and allowed many to imagine what it might be like to have the children in the United States permanently.


The present invention relates to a rubber wiper blade with a coating film on both surfaces of the lip portion, wherein the coating film comprises a particulate solid lubricant and a binder, and wherein the binder has a 0.5% modulus of 1 MPa or more and an elongation at break of 1% or more having.


The constitutive secretion of latent TGF- (cid:2) by many cell types in culture suggests that extracellular mechanisms to control the activity of this potent cytokine are important in the pathogenesis of the diseases in which this cytokine may be involved, including fibrotic disorders. In this study, we focused on the (cid:1) v (cid:2) 3 integrin, which is recently demonstrated to function as an active receptor for latent TGF- (cid:2) 1 through its interaction with latency-associated peptide- (cid:2) 1, and investigated the involvement of this integrin in the pathogenesis of scleroderma. Scleroderma fibroblasts exhibited increased (cid:1) v (cid:2) 3 expression compared with normal fibroblasts in vivo and in vitro. In scleroderma fibroblasts, ERK pathway was constitutively activated and such abnormality induced the up-regulation of (cid:1) v (cid:2) 3 . Transient overexpression of (cid:1) v (cid:2) 3 in normal fibroblasts induced the increase in the promoter activity of human (cid:1) 2(I) collagen gene and the decrease in that of human MMP-1 gene. These effects of (cid:1) v (cid:2) 3 were almost completely abolished by the treatment with anti-TGF- (cid:2) Ab or TGF- (cid:2) 1 antisense oligonucleotide. Furthermore, the addition of anti- (cid:1) v (cid:2) 3 Ab reversed the expression of type I procollagen protein and MMP-1 protein, the promoter activity of human (cid:1) 2(I) collagen gene, and the myofibroblastic phenotype in scleroderma fibroblasts. These results suggest that the up-regulated expression of (cid:1) v (cid:2) 3 contributes to the establishment of autocrine TGF- (cid:2) loop in scleroderma fibroblasts, and this integrin is a potent target for the treatment of scleroderma. The Journal of Immunology, 2005, 175: 7708–7718.


This document describes the requirements and details of the thermo-mechanical spine that forms part of the SCT end-cap module. The assembly processes are explained and reviews are given of the components and product specifications. The methods of achieving both component assurance and spine quality assurance are described, and finally the production schedule is presented. Prepared by : Checked by : Approved by :


This work improves period uniformity over larger-area gratings in a two-spherical beam interference lithography (IL) setup. Using a concave vacuum chuck, we have experimentally demonstrated the modified optical setup to reduce period variation (chirp) on a 4-inch silicon substrate. The change in the grating period is significantly reduced compared with the interference exposure on a flat silicon substrate. Wavefront aberration measurement on a curved exposed substrate showed improved grating linearity.


An old IR-27C infrared spectrophotometer is modified to measure the emissivity ofradiating materials which are used in the infrared heating and drying technique. Theconstructions of the whole equipment and several important parts are described indetail. The performance of the equipment is illustrated by measuring the emissivity ofblackened stainless steel and fused quartz. Some factors which cause the errors arediscussed.


The nutritional status of 2 1 patients sutTening from bulimia nervosa was evaluated by anthropometnic and itii-munologic indexes in comparison with a control group (ii = I5. In addition, the influence of body mass index (BMI: in kg/rn2) values and vonhiting episodes on the nutritional status of hulirnic patients was assessed. Anthropornetny showed no signs of nialnu-trition in either group. except for those patients with low weights (BMI < 19). Bulimic patients had lower lymphocyte counts than did control subjects. except fir those without vomiting (NVBN). All 1' lymphocyte subsets tested as well as CD57 cells were lower (22% and 55%, respectively) in bulirnic patients than in control subjects, but the CDI9 cell subset remained unmodified. The I(cid:1)w-weight bulimic group (LWBN) had lower CD4 cell counts than did the normal-weight (BMI > 19) bulirnic group. The NVBN lymphocyte suhpopulations similar to those in the control group, except for CD57, which was lower. The bulirnic patients with vomiting had the lowest cell subset values. These results suggest a depleted nutritional status in all bulirnic patients studied, even those with normal weights. The LWBN group had the lilOst depleted nutritional status and the NVBN group was least affected at a subclinical level. CD57 can be considered a good marker of nutritional status in this syndrome because it was the only subpopulation altered in all groups.


This activity is based on the fact that online learning is caused by the outbreak of the covid 19 outbreak. In this case, the aim is to increase the ability, understanding, and enthusiasm of kindergarten and elementary school students in online learning. The target is Kindergarten and Elementary School students in Bleber Kras Kediri Village using discussion methods and learning assistance. This activity was carried out in 10 meetings and each meeting lasted for 3 hours. When the activity takes place, the study group is limited to five children per hour, and in a day there are three groups that take tutoring. As a result, students began to enthusiastically carry out online learning and also parents of students participated in supporting tutoring activities during this pandemic in Bleber Kras Village, Kediri. Students are also more assisted in carrying out tasks from school.


Ambient temperature is an important factor influencing the reliability of electromagnetic relays. The effect of different environmental temperatures on relay lifetime can be examined through the Cox-proportional hazards model (PHM). In this paper, relay life tests were carried out at -20 °C, 20 °C, and 55 °C. Relay lifetime data were collected at various temperature conditions and were integrated to establish a Weibull PHM of electromagnetic relays. A comparative analysis of the experimental data indicates that an ambient temperature has a significant influence on contact resistance. The characteristic life, the mean life, and the probability density function of failure under temperature conditions not tested in the conducted experiment were estimated through the implementation of Cox PHM. Both the characteristic life and mean life decrease significantly with increasing ambient temperature. The perspectives and the methodology of the implementation of the Weibull PHM presented in this paper are generic and could be adopted for other systems/products directly.


OBJECTIVE
To present the clinical experience with direct-acting antivirals (DAAs) for chronic hepatitis C in HIV-positive patients.

MATERIALS AND METHODS
Longitudinal and prospective case series of HIV-positive patients treated with DAAs for chronic hepatitis C between May 2019 and April 2020 at the Infectious Diseases Service of Hospital G. Almenara, EsSalud. The primary outcome was sustained virologic response to hepatitis C virus (HCV) 12 weeks after completion of DAA therapy. Secondary outcomes were tolerability and safety.

RESULTS
Ten patients were included in the study, two were women (20%). Two patients had cirrhosis (20%). All patients had suppressed HIV viral load prior to DAA therapy. Patients received a 12-week regimen based on sofosbuvir: one with daclatasvir separately, and the remaining nine with velpatasvir combined in a single tablet per day. The sustained virological response of HCV was evaluable nine cases. In these, the HCV viral load was undetectable. No occurrences were recorded regarding tolerability and safety during therapy with the indicated DAAs.

CONCLUSIONS
This present investigation is the first clinical experience in Peru with DAAs for chronic hepatitis C in HIV-positive patients. Virologic response, tolerability, and safety against daclatasvir and velpatasvir, each in conjunction or in combination with sofosbuvir, were optimal in the case series presented.


Cadmium is a toxic heavy metal which is considered a dangerous environmental pollutant and has a detrimental effect on the organs of the reproductive system, the period of implantation and the development of embryos. The experiment presented in this article established the effect of cadmium salts (chloride and citrate) on the general progress of embryogenesis. For this purpose, 60 rats were randomly divided into three groups: control, experimental group with cadmium chloride exposure and experimental group with cadmium citrate exposure. Cadmium chloride solvent, cadmium citrate solvent at a dose of 1.0 mg/kg and distilled intragastric water were injected from the first to the thirteenth (first subgroup) and from the first to the twentieth days of embryogenesis (second subgroup). When cadmium chloride was injected, total embryonic (by 4.24 and 3.67 times), pre-implantation (by 6.50 and 14.03 times) and post-implantation mortality (by 3.07 and 2.49 times) increased with a reduction of the number of surviving fetuses by 24.0% and 25.9% compared with the control group on the 13th and 20th days of embryogenesis respectively. At the same time, during exposure to cadmium citrate, indicators of total embryonic mortality increased by 4.02 and 3.52 times, pre-implantation mortality by 6.04 and 13.03 times, and post-implantation mortality by 3.09 and 2.26 times, and indicators of the number of live fetuses decreased by 18.3% and 22.2% in relation to the control group. When determining the accumulation of cadmium in embryos on the 20th day of gestation, polyelement analysis of biological materials using the atomic emission method with electric arc atomization revealed a 15.83-fold increase in cadmium chloride and 9.00 times in cadmium citrate relative to the control group. Embryolethality rates increased in animals of both experimental groups while the number of live fetuses per female decreased, which indicated an obvious embryotoxic effect of cadmium compounds. It is would be useful to conduct histological studies, which will help detect changes at the tissue level and possibly explain the level of embryonic mortality.


Penetration depth (PD) is a measure that indicates the amount of overlap between two objects. The most popular version is the translational penetration depth, which is the minimum amount of distance by which the two overlapping objects must be translated in order to separate them. A variant of this classical version of the problem is computation of generalized penetration depth (GPD), in which rotational motion is also allowed in addition to translation. In this paper, we survey important results related to computation of PD and GPD for objects in R and R.


The aim of this study was to evaluate the efficacy of various disinfectants in different concentrations against embryonated Toxocara canis eggs. For this purpose, 2.5%, 5%, 7.5%, and 10% iodine, 2% glutaraldehyde, 10% benzalkonium chloride, 7% sodium hypochloride, 1% potassium permanganate, 70% ethyl alcohol, 10% potassium hydroxide and 3% phenol solutions were used as the disinfectants. This study was performed both in vitro and in-vivo. In the in vitro experiment, T. canis eggs were treated with disinfectant solutions in different time intervals, and larval motility was observed under X400 magnification with an inverted microscope. Microscopic examinations revealed that T. canis eggs treated in 2.5%, 5%, 7.5%, and 10% iodine solutions were completely non-motile at 120, 60, 40, and 40 minutes post-treatment respectively, whereas the eggs treated in the all other disinfectants were still motile after 24 hours. In the in-vivo study, 1000 embryonated eggs treated with disinfectants were inoculated each mouse via the oral route, and their brain tissues were examined for larval presence on the 7th day post-inoculation. In addition, a control group was set up for comparison with the study groups. No T. canis larvae were observed in mice inoculated with eggs treated with any of the iodine solutions. However, larvae were observed in the other study groups inoculated with eggs treated with the other disinfectants. These results showed that only the iodine disinfectants produced a statistically significant difference (p


BACKGROUND: The increasing industrial demand for carotenoids has led to growing interest in their bioproduction. The need to reduce production costs has encouraged the use of low-cost agroindustrial substrates. In this context, this work studied the pretreatment of Mozzarella cheese whey and the use of the pretreated whey as fermentation medium for the bioproduction of carotenoids by Sporidiobolus salmonicolor CBS 2636.

RESULTS: Bioproduction was carried out in an orbital shaker using a 10 mL L−1 inoculum, incubation at 25 °C and a stirring rate of 180 rpm for 120 h in a non-illuminated environment. The carotenoids were recovered using liquid N2 combined with dimethyl sulfoxide for cell rupture and an acetone/methanol mixture (7:3 v/v) for extraction. The maximum concentration of total carotenoids obtained was 590.4 µg L−1 in a medium with 900 g L−1 cheese whey hydrolysate and 4 g L−1 K2HPO4 at 180 rpm, 25 °C and pH 4.

CONCLUSION: The use of enzyme-hydrolysed cheese whey was more effective in carotenoid bioproduction by S. salmonicolor CBS 2636 than the use of acid-hydrolysed cheese whey. The concentration of total carotenoids obtained with the enzymatic hydrolysate was six times higher than that obtained with the acid hydrolysate. Copyright © 2009 Society of Chemical Industry


Functional iron oxide nanoparticles (NP) have been synthesized in a one and two-step method using, for the first time, a natural functional glycolipid belonging to the family of sophorolipids (SL). According to the synthesis strategy, magnetic properties can eventually be tuned, thus putting in evidence the direct effect of the glycolipid on the final material's structure (maghemite and ferrihydrite). Here, we put in evidence the SL surface complexing properties on the metal oxide particles via its free COOH group as well as its interest as hydrophilic and stabilizing coating agent by mean of its carbohydrate moiety (sophorose). Most importantly, we have shown that the sophorose group is readily accessible to the outer layer of the nanoparticles by probing the specific interactions between the carbohydrate


A checklist and dichotomous key to 128 species of bats known from South Asia including Afghanistan, India, Pakistan, Nepal, Bhutan, Bangladesh, Sri Lanka and Maldives is provided. Character matrices for families, genera and species are also included. This article also briefly reviews their distribution (both physiographic and country-wise), status and main identification characters


The statistical modeling of social network data needs much effort  because of the complex dependence structure of the tie variables. In order to formulate such dependences, the statistical exponential families of distributions can provide a flexible structure. In this regard, the statistical characteristics of the network is provided to be encapsulated within an Exponential Random Graph Model (ERGM). Applying the ERGM, in this paper, we follow to design a statistical process control through network behavior. The results demonstrated the superiority of the designed chart over the existing change detection methods in controlling the states. Additionally, the detection process is formulated for the social networks and the results are statistically analyzed.


Our work examines the problem of estimating the potential business value of evolving service-oriented applications, based on the value of the new services this evolution is anticipated to enable and the estimated cost of the development effort. We have adopted COCOMO II as the software-development cost model, as it is designed to account for evolutionary software development. However, it is clear that the model will have to be extended in order to represent the particular idiosyncrasies of this new development style. As it is, it can estimate the cost of adapting source code; however, SOA development also involves developing and adapting declarative composition specifications, which may be a fundamentally different process. Specifically, research into the cost of creating a Web service composition is required. We have also adopted real-option theory for modeling the business services that can be delivered based on an envisioned service-oriented application. Our intuition is that the fundamentally compositional nature of service-oriented development comes with the built-in advantage of enabling interesting evolution at the design level (as opposed to the code level). Therefore, we believe that there is a very direct mapping between the design-evolution potential of a service-oriented application and the business services that it can support in the future. Consequently, we hope to develop a real-option model grounded to the SOA development process. Along these lines, we are developing a tool to assist in this research. The tool will help the user to reason financially about a proposed change to a web service, constructing a fairly complete view of the situation and the possible futures associated with it. Traditionally, the value of a software service has been determined solely by the business community, with only the occasional regard for the possible value of flexibility. Conversely, the cost of developing software has been studied extensively by the computing science community. This work is an attempt to further join these two fields for a more complete view of web-service econometrics.


A digital control scheme for single‐inductor‐dual‐output (SIDO) regulator is shown. Amble of calculation power, in the deep‐sub‐micron Liquid Crystal Display (LCD) driver technology, enables maximum driving capability and efficiency to be achieved in a very constraint space. Operation frequency, on‐time of switches, and dual output phase allocation are determined by a novel algorithm for the most robust and efficient control.


Complex treatment of cows at mastitis with application of cold, novokainovy blockade on Logvinova, intravenous administration of 10% of solution of chloride of sodium and 40% of solution of glucose promotes fast recovery of cows at sharp serous mastitis and positively influences their hematologic indicators.


The "Smart Grid" refers to various efforts to modernize the power grid through the application of intelligent devices. This paper describes current thinking by members of the Distribution System Analysis Subcommittee (DSA SC) on how distribution system analysis might evolve to support the Smart Grid. Various issues related to Smart Grid and distribution system analysis are identified. The essential characteristics of distribution system analysis tools to support these issues are discussed. Relevant activities of the DSA SC are described.


The purpose of this study was to develop creative game models with natural media for early childhood. This research uses research and development methods to produce certain products, and test the effectiveness of these products. This research was conducted at the Teratai Kindergarten in Makassar City using a purposive sampling technique. The data collection techniques used were observation, interviews, questionnaires and documentation. The data analysis techniques used in the development of the product design (prototype) learning models were in the form of a descriptive picture and a description of practicality before testing the product. The results showed that the form of the creative game design with natural media for early childhood consists of two components. Namely, the philosophy component of the model, including the rationality of the model, objectives, teacher roles and system support, while the operational components of the model are detailed in all types of activities with various themes or subthemes. All activities are packaged with the aim of developing children's creativity.


1 Wool alcohols have been subjected to oxidation under varying conditions and progressive changes in physical and chemical properties have been observed. Such changes include–rise in acid and saponification value, decrease in acetyl value and cholesterol content. 2 The interfacial tension‐reducing power of total wool alcohols and some isolated fractions have been measured using the pendant drop method. This value does not show any appreciable change as oxidation proceeds. 3 Wool alcohol emulsions suffer breakdown on storage. This is accompanied by rise in acid value of the oil phase. Both effects can be retarded by the inclusion of antioxidants in the formula. 4 Some tentative mechanisms based on the results obtained have been put forward to explain the changes which wool alcohols undergo on oxidation. Much of the practical work was carried out by Miss E. Graydon, P. Hills and G. Sumpter. The authors wish to thank A. G. Wright for his work in connection with the design and construction of the two types of apparatus illustrated and the Directors of Herts Pharmaceuticals Limited for permission to publish this work.


THE USE OF LINEAR EQUATIONS FROM THE MOHR-COULOMB THEORY MAY LEAD TO IMPORTANT ERRORS IN THE STATISTICAL INTERPRETATION OF THE RESULTS FROM TRIAXIAL COMPRESSION TESTS AND DIRECT SHEAR TESTS ON CONCRETE, ROCK, GRAVEL, ROCK-FILL, ETC. TO PREVENT SUCH ERRORS, IT IS SUGGESTED TO USE A MORE GENERAL MOHR CURVE, GIVEN BY A SECOND DEGREE EQUATION WHICH CAN BE DEFINED THROUGH 3 CHARACTERISTIC PARAMETERS: SHEAR STRENGTH FOR NORMAL STRESS, INITIAL SHEARING RESISTANCE ANGLE (TANGENT TO THE CURVE AT ITS INTERSECTION WITH THE TANGENTIAL STRESS AXIS), AND MAXIMUM TENSILE STRESS. THE PAPER DESCRIBES THE WAY OF OBTAINING THE GENERAL MOHR CURVE AS DEFINED ABOVE, FROM THE RESULTS OF TRIAXIAL TESTS AT LOW PRESSURES BY MEANS OF AN AUXILIARY REFERENCE CURVE, AND FROM THE RESULTS OF SIMPLE COMPRESSION AND TENSILE TESTS.


A bibliographic document describing the community of Germans who immigrated to Russia at the invitation of the Russian government. It is also the only systematic compilation of Russian-language sources relating to the German- Russians. Professor Long has written an eminently readable introductory essay to this comprehensive, annotated bibliography. The full spectrum of military, political, and social history is simply presented for quick, authoritative research on World War I. Although deliberately selective, it is of considerable to the specialist in military 20th century research and comparative efficiency of socialism is explored in depth in these studies. Focusing on the "Soviet Model," Bergson discusses recent developments in planning and growth strategy. In contrasting Eastern and Western economic performance, Bergson uses sophisticated quantitative techniques to compare productivity while allowing for differences in historical factors. "This is nothing Jess than the social history of the group from which top Soviet leaders have been drawn down to the present day. Not only does Bailes describe in detail the process by which this group was formed and transformed under Stalin, but, by means of case studies, he identifies the causes of the resistance to innovation that still vitiates Soviet plans for economic betterment."


Security is top concern for the people of IT from the past. With the advent of new technologies the severity of the problem has been changing its shape. A number of threats and their counter measures had been identified. Similar is the Cloud based environments. In spite of large number of features provided by Clouds, they are not able to attain attention of large number of business community. Cloud Security Alliance (CSA) is the top most working group working on the security issues of the Clouds. In this paper we have studied the various security attacks (in general) with reference to the Clouds (as per The Treacherous 12 Cloud Computing Top Threats in 2016, CSA report defeating insider threat survey(2016) ,Cyber Security Trends Report (2017)) and Malicious Insider attacks (in particular).


Local Public Administrations could play a relevant role in the building of a strongest European identity. This issue derives not only from the capability to be directly in touch with citizens but also because they represent the culture of service delivered from the bottom. This means that Europe has to facilitate the Life Long Learning of Managers and Staff of local administrations with programs of temporary mobility and learning. As the Directorate-General for Education and Culture of the European Commission recommended some years ago, initiatives like the PLOTEUS portal for learning opportunities, work in this direction but for a more effectiveness of this strategy is necessary a strongest policy of incentives and facilities and a clear framework similar to experienced Tempus and Leonardo programs for Universities and Research.


This paper presents the different approaches of a Hybrid Renewable Energy System (HRES) injection power management. The HRES is connected to the Grid and to the Consumer by using a three-phase system. The two main operation states of the HRES are the Grid connected and OffGrid modes. Two different systems of control and management of the three-phase inverter of the HRES are needed. This inverter is responsible for power exchange between interior part of the HRES, as the PV production and the Storage system, and the external part, as the Three-phase system of HRES and the Consumer. The work describes the method of voltage control in the Off-grid mode, and the current control in the Grid connected mode with voltage synchronization with practical validation.


The article is devoted to the peculiarities of legal relations in the field of international cooperation in combating migrant smuggling and human trafficking. It has been determined that smuggling of migrants and human trafficking have long been among the transnational crimes in terms of profitability. The article proves that this area is characterized by clearly structured and organized criminal syndicates, which direct their profits to the development of other even more dangerous activities. The article describes the main features of trafficking in human beings under the Protocol to Prevent, Suppress and Punish Trafficking in Persons, Especially Women and Children, which complements the UN Convention against Transnational Organized Crime. Research of influence of exogenous and endogenous factors on development of modern world trafficking. It is determined that international cooperation in criminal matters is one of the most important prerequisites for the organization of combating and preventing trafficking in human beings and smuggling of migrants. The article outlines the key elements of the implementation of trafficking in human beings in accordance with Article 3a of the Protocol to Prevent and Suppress Trafficking in Human Beings. A number of international normative and legal documents regulating the implementation of the state policy on combating human trafficking and smuggling of migrants have been proposed and paid attention to. It has been proven that, according to Europol, smuggling of migrants is carried out by criminal networks that provide various services: from forgery of documents to bribery of law enforcement officials. Various forms of international cooperation are superficially described: extradition of criminals, mutual legal assistance, transfer of criminal proceedings to another country, transfer of convicts, cooperation for confiscation, cooperation between law enforcement agencies, including information exchange and cooperation in investigations, joint investigation using special investigative methods.


This paper studies near infrared technology for measuring moisture content in solid substance. After analyzing and improving traditional moisture instruments and discussing their disadvantages, we present a measuring scheme and instrument structure design with high performance and stability. The novel instrument utilizing near infrared range analysis (NIRA) technology possesses characteristics of on-line working, high accuracy, distribution and non-contact measurement.


Image segmentation is a fundamental task in automatic image analysis. However, there is still no generally accepted effectiveness measure which is suitable for evaluating the segmentation quality in every application. In this paper, we propose an evaluation framework which benefits from multiple stand-alone measures. To this end, different segmentation evaluation measures are chosen to evaluate segmentation separately, and the results are effectively combined using machine learning methods. We train and implement this framework in our brand-new segmentation dataset which contains images of different contents with segmentation ground truth and Weizmann segmentation database (WSD). In addition, we provide human evaluation of image segmentation pairs to benchmark the evaluation results of the measures. Experimental results show a better performance than the stand-alone methods.


The design of multimedia electronic classroom is a comprehensive project. Low cost is important, but credibility should be guaranteed. This article proposed some experiences in the design and building of multimedia electronic classroom,which can be provided to the relative school for reference.


Carbon‐13 NMR spin–lattice relaxation times, T1, and nuclear Overhauser effect data were obtained for neat tetra‐n‐octyltin at 22.5 and 100.6 MHz over a wide temperature range. T1 values were also measured at 25.16 MHz at pressures up to 211 MPa. The ambient‐pressure data were fitted to the 'model‐free' two‐correlation time spectral density with a temperature‐dependent order parameter, S2. The pressure data were interpreted by assuming that internal motions of the octyl chain are independent of pressure while the overall (tumbling) motion and S2 are pressure dependent. The values of the motional parameters for tetra‐n‐octyltin lie in the ranges expected for compounds containing long n‐alkyl chains. The results show that this approach is applicable to complex liquids such as synthetic lubricants of the polydecene type.


A 17-year-old teen went to the ED after suffering his second syncopal episode in the last 6 months. He had shrugged off the first episode as not eating enough before a jog, but this time he hadn't been doing anything active and his parents witnessed the syncope and what appeared to be a seizure. He reported that he had been feeling heart palpitations prior to the event. Further blood tests showed hypokalemia.


The influences of quenching temperature on the microstructure and property of Cr5 steel for cold roller were studied by scanning electron microscopy,transmission electron microscopy and X-ray diffraction.The carbide in the microstructure of Cr5 steel after quenching and tempering treatment is mainly characterized as Cr7C3.Compared with the spheroidic annealing state,the carbide under quenching and tempering condition is refined,about 100~300 nm.The hardness increases monotonously after quenching at 875 ℃~950 ℃.By contrast,the hardness decreases when the quenching temperature above 950 ℃.


The stability of a toroidally symmetric sharp boundary plasma is studied in a wall whose cross section is an arbitrary shape. The wall stabilization has an effect on a fat plasma. The kink mode of the plasma has two stable regions in which toroidal fields and poloidal fields are, respectively, dominant. The second harmonic plays an important role for the stability. For a fixed aspect ratio of the plasma, the stable regions increase accordingly as the plasma shifts outward. If circular walls, elliptical walls, and oval‐shaped walls have the same cross‐sectional area, the circular wall is the worst case for the stability.


Socially Tangible Media (STM) is a term describing an emerging category of products that aim to link social data to the materiality of objects and spaces. Digital networks are increasingly used to connect on a social level, while a growing number of objects are becoming part of such networks. The aim of this graduation project is to provide designers with a toolbox that will assist them in designing for the Socially Tangible Media field.


Nanoproducts find wide-ranging applications, from medicine and pharmaceutics to electronic industry, optics and environmental protection. Metallic nanoparticles (NPs) with antibacterial properties represent a promising alternative approach to antibiotics. Copper nanoparticles display high biological activity, comparatively low cost, ecological safety and could be considered as promising multifunctional antibacterial agents. Preparation of new antimicrobial release systems based on Cu NP and biological polymers will contribute to create effective antimicrobial agent. The purpose of current research is to examine the antibacterial activity of the Cu NPs and Cu NPs/chitosan solution against methicillin-resistant Staphyloccus aureus MRSA and multidrug resistant E. coli clinical isolates. Cu NPs were synthesized via chemical reduction method using ginger (Zingiber officinale) and L-ascorbic acid. Chitosan (200 and 500 kDa)-NPs solution with different concentrations was prepared before experiment. X-ray diffraction (XRD) technique, scanning electron microscopy (SEM), SEM energy dispersive microanalysis (EDS), infrared (FTIR) and UV-Vis spectroscopies were used for NPs characterization. The antimicrobial activity of the Cu NPS and CuNP/chitosan solution was tested against 10 MRSA and 5 multidrug-resistant E. coli clinical strains. Physicochemical characterization of Cu NPs showed that they consist of copper core and copper (IV) oxide shell, and the surface of the NPs contained organic compounds originated from ginger and ascorbic acid that served as capping and reducing agents. Cu NPs were approximately 15–20 nm in size and exhibited an ability to self-organization into roundish structures 770±90 nm in size. Pure copper NPs, synthesized via chemical reduction method, affected multiresistant clinical strains of S. aureus and E. coli in concentration of 0.35 μg/ml and 0.7 μg/ml. NPs in 200 kDa chitosan solution effective against MRSA strains in concentration 0.17 μg/ml. But Cu NPs in 500 kDa chitosan solution have no antibacterial effect.


Diffusion bonding process of aluminium 1070A concerning production of microchannel heat exchangers (MCHE) has been investigated. It has been proposed to raise manufacturability of the process owing to introduction into contact zone of joining details composition on the basis of sodium silicate before welding. The results of investigations of microstructure and chemical composition of welded joints and also mechanical strength of products have been presented.


337 Background: Diabetes mellitus (DM) and hyperglycemia have been widely considered to be associated with the risk of pancreatic cancer. However, the aim of this study was to evaluate the relationship between glycemic control and the efficacy or safety in pancreatic cancer pts receiving treatment with nab-Paclitaxel (nab-PTX) plus Gemcitabine (GEM). Methods: We retrospectively reviewed 285 pts with unresectable pancreatic cancer with nab-PTX plus GEM as the first-line chemotherapy from December 2014 to March 2017 at the National Cancer Center Hospital East, Kashiwa, Japan. The pts were divided into two groups, average blood glucose level during the period of chemotherapy was less than 160 mg/dL (Group GC: Good glycemic control group) and more than 160 mg/dL (Group PC: Poor glycemic control group). Results: A total of 285 pts were enrolled. Median age was 66 years (range: 26-84) and males/females: 180/105, PS (0-1/2-3): 272/13, stage (III/IV): 77/208. There were 226 pts in GC group and 59 pts in PC group. No significant differences were seen in the overall survival between Group GC and PC (median: 16.1 months vs. 13.8 months, p = 0.344) and in the progression free survival between the two groups (median: 7.5 months vs. 8.2 months, p = 0.862). The incidence rate of grade 2-3 chemotherapy-induced peripheral neuropathy (CIPN) was significantly higher in Group PC compared with Group GC (Group GC 28.3%, Group PC 45.8%, p = 0.010). Univariate and multivariate analyses identified glycemic control as significant independent factors associated with the incidence of grade 2-3 of CIPN (Odds ratio 2.182, 95% CI 1.20-3.96, p = 0.010). There was no significant difference in the relative dose intensity of nab-PTX between two groups (median, 56.6% in group GC, 56.5% in group PC, p = 0.952). Conclusions: Glycemic control during the chemotherapy with nab-PTX plus GEM in unresectable pancreatic cancer was not associated with OS. The incidence of severe CIPN was higher in pts with poor glycemic control compared with good glycemic control.


In this thesis a methodology for measuring vibrations has been produced andinvestigated for APID 60, a rotorcraft in a Vertical Take-off and landing remotelypiloted aircraft system (VTOL RPAS). A c ...


ABSTRACT In this paper, I argue for an Aristotelian way of accommodating supererogation within virtue ethics by retrieving an account of moral heroism and providing a picture of different degrees of virtue. This, I claim, is the most appropriate virtue-ethical background allowing us to talk about supererogation without falling prey to several dangers. After summarizing the main attempts to deny the compatibility of virtue and supererogation, I will present some recent proposals to accommodate supererogation within virtue ethics. Next, I will argue that these proposals raise substantial worries. I will then offer an analysis of heroism and the degrees of virtue to outline my own alternative definition of supererogation in terms of heroic virtue.


Abstract We undertook skin-grafting between populations to determine whether Aspidoscelis rodecki originated from single, or multiple, parthenogenetically capable hybrids. We transplanted 292 skin grafts within and between the two most geographically distant populations, considering only grafts in animals surviving more than 45 days. Two hundred fifteen grafts were analyzed. Histocompatibility within (100%) and between (97.9%) populations suggests that A. rodecki was derived from a single, parthenogenetically capable, hybrid.


What turned out to be perhaps the most traumatic year in Indonesia's New Order history began as a period of intermittent social unrest in both Java and the outer islands. But the general sense was one of predictability: the government's GOLKAR party would win in the May parliamentary elections, the economy would surge ahead at 7% growth or better, and the pieces would fall into place for Soeharto's anointment in March 1998 for his seventh five-year term. By the last month of 1997, acute uncertainty clouded all those premises.


By means of simulation and phase portrait method of chaos numerical analysis method and largest Lyapunov exponent method, and taking the planar 3R rigid redundancy robot as the object of study, the chaos phenomena in self -motion was studied when end-effectors of the robot with a control of resolved motion were tracing repeatedly a closed path in the working space and carrying out an obstacle avoidance plan. The study shows that the self-motion is a regular movement when resolving the kinematics inverse solution of redundancy robot based on the velocity control method of resolved motion, but the self-motion will be a chaos movement when resolving the kinematics inverse solution of redundancy robot based on the acceleration control method of resolved motion.


In sheep sustained entirely by intragastric infusions, isoenergetic amounts of dietary butyrate or octanoate gave identical 3-HB entry rates without any change in glucose synthesis whereas with heptanoate, these rates are 50% lower and 20% higher, respectively. A glucogenic effect of odd carbon medium-chain fatty acids is suggested. Key words: Sheep, nutrient-infusion, medium-chain fatty acids, metabolism


We report detections of the [OIII]$\lambda$4364 auroral emission line for 16 galaxies at z=2.1-8.7, measured from JWST/NIRSpec observations obtained as part of the Cosmic Evolution Early Release Science (CEERS) survey program. We combine this CEERS sample with 9 objects from the literature at z=4-9 with auroral-line detections from JWST/NIRSpec and 21 galaxies at z=1.4-3.7 with auroral-line detections from ground-based spectroscopy. We derive electron temperature T_e and direct-method oxygen abundances for the combined sample of 46 star-forming galaxies at z=1.4-8.7. We use these measurements to construct the first high-redshift empirical T_e-based metallicity calibrations for the strong-line ratios [OIII]/H$\beta$, [OII]/H$\beta$, R23=([OIII]+[OII])/H$\beta$, [OIII]/[OII], and [NeIII]/[OII]. These new calibrations are valid over 12+log(O/H)=7.0-8.4 and can be applied to samples of star-forming galaxies at z=2-9, leading to an improvement in the accuracy of metallicity determinations at Cosmic Noon and in the Epoch of Reionization. The high-redshift strong-line relations are offset from calibrations based on typical $z\sim0$ galaxies or HII regions, reflecting the known evolution of ionization conditions between $z\sim0$ and $z\sim2$. Deep spectroscopic programs with JWST/NIRSpec promise to improve statistics at the low and high ends of the metallicity range covered by the current sample, as well as improve the detection rate of [NII]$\lambda$6585 to allow the future assessment of N-based indicators. These new high-redshift calibrations will enable accurate characterizations of metallicity scaling relations at high redshift, improving our understanding of feedback and baryon cycling in the early universe.


A series of samples in the system CuGaxIn1−xTe2, 0 ≤ x ≤ 1, has been synthesized and characterized by X-ray diffraction. All the samples have a chalcopyrite-type structure, the unit-cell parameters a and c and the ratio c/a changing linearly with x. The unit-cell parameters for the compounds with x = 1, 0.80, 0.65, 0.50, 0.30, 0.15 and 0 and the powder diffractometer data for x = 1, 0.5 and 0 are given at 298 K. CuGaTe2: a = 6.021(2), c = 11.937(5) A, V = 432.75 A3, Dx = 5.96 g cm− 3; CuGa0.80In0.20Te2: a = 6.053(2), c = 12.039(4) A, V = 441.09 A3, Dx = 5.99 g cm− 3; CuGa0.65In0.35Te2: a = 6.084(2), c = 12.107(7) A, V = 448.14 A3, Dx = 5.99 g cm−3; CuGa0.50In0.50Te2: a = 6.107(2), c = 12.177(7) A, V = 454.15 A3, Dx = 6.01 g cm−3; CuGa0.30In0.70Te2: a = 6.144(2), c = 12.296(7) A, V = 464.16 A3, Dx = 6.01 g cm−3; CuGa0.15In0.85Te2: a = 6.168(3), c = 12.355(10) A, V = 470.04 A3, Dx = 6.03 g cm−3; CuInTe2: a = 6.195(2), c = 12.418(6) A, V = 476.58 A3, Dx = 6.04 g cm−3. The JCPDS Diffraction File Nos. are: 34-1500 for CuGaTe2; 34-1498 for CuInTe2; 34-1499 for CuGa0.50In0.50Te2.


Introduction. Steroid-refractory graft-versus-host disease (srGVHD) is one of the most severe and life-threatening complications of allogeneic hematopoietic stem cell transplantation. Currently, there is no standard treatment for this complication. In addition, there is no data on the pharmacoeconomics of various methods in the Russian Federation. The objective is to compare the effectiveness and cost of treatment of acute and chronic srGVHD, as well as the use of different approaches in therapy. Material and methods. We have conducted a pilot study in 12 srGVHD patients treated with ruxolitinib and in 24 patients of well-matched historical control, who treated with etanercept for the acute srGVHD and with extracorporeal photopheresis for chronic srGVHD. Results. The 6-month therapy of acute GVHD was associated with significantly higher cost than therapy of chronic GVHD (4.138±2.672 vs 1.862±1.122 thd. rub., р=0.004). The major factors driving up the costs were bacterial infections (р=0.022), opportunistic viral infections (р<0.001), severity of GVHD at the start of a therapy (р=0.013) and GI involvement (р=0.006). There was no difference in 1-year failure-free survival in acute (50 % vs 67 %, р=0.9) and chronic GVHD (87.5 % vs 87.5 %, р=1.0) between ruxolitinib and the control group, although the overall response was faster in ruxolitinib group (100 % vs 71 %, р=0.035, when assessed at 28 days in acute and 12 weeks in chronic srGVHD). The mean 6-month overall costs in the ruxolitinib were higher compared to the control group (1534 thd. rub. higher for acute and 541 thd. rub. higher for chronic GVHD), however this might be attributed to higher number of previous lines in the ruxolitinib group. Conclusions. It is revealed that the treatment of acute srGVHD requires significantly higher economic costs than chronic srGVHD. The power of this study does not allow to draw conclusions regarding the efficacy of different methods. Further studies are required to determine the optimal therapy of srGVHD.


Intra-daily movements in the yen/dollar exchange rate were examined in four non-overlapping segments within each business day from January1980 to September 1985. The empirical results yielded several conclusions. First, most depreciation of the yen (appreciation of the dollar) from late 1982 to early 1984 occurred in the New York market. The direction of the yen was mostly neutral in the Tokyo market. Also, the volatility of the exchange rate decreased considerably in the Tokyo market. The volatility in the New York market, on the other hand, did not decrease untilvery recently. Second, market efficiency was examined in terms of the random-walk behavior of short-run movements in the yen/dollar rate. Information on the preceding segments within a day was sometimes significant in predicting the exchange rate movement in a market. Third, there is evidence of the "profit-taking" behavior, or overshooting, in that a large jump (more than 3 absolute yen) in any market tends to be reversed by a fifth of the jump during the same day in the next market. Finally,the relative effects of news from the U.S. and Japan were examined explicitly both with respect to possible major events behind large jumps andthe response of the yen/dollar rate to particular economic announcements in both countries. Over the entire sample period, news concerning the U.S. money stock had the only significant effects.


Recognition of the face is one of the biometric techniques used to recognize any facial image. Since birth, faces have played a crucial role in any individual's social interaction that gives the individual a distinctive identity. Face detection and recognition is a very popular topic in biometric research as it is used for the safety and security of an individual. Face recognition technology has attracted a large number of researchers due to its wide range of application value as well as market potentials, such as fraud detection and video surveillance. Face recognition plays a very important role in the surveillance system, as there is no need for the participation of an object. We used an image set algorithm with the help of OpenCV and Python programming and having a pre-existing dataset of faces. The module is divided into three sub modules: 1] Detection module 2] Training module 3] recognition module. Index Terms Face detection, Face Recognition, OpenCV, Haar cascade, Adaboost algorithm.


This is a joint experimental and computational research effort on the aerodynamics of perforated surfaces inclined to a freestream. The goal is to characterize the key parameters affecting the flowfield in order to construct a macroscopic computational model that obviates resolution of the detailed perforations. The model simulates the effects of the perforated surfaces by locally applying a body force term in the momentum equation. The study considers wedge-shaped deflectors used for jet noise reduction in turbofan engine nozzles in the form of flaps with varying angles and perforation shapes. The experiments measured the mean velocity field inside and in the wake of theflapswhile the numerical analysis comprised direct computations of simplifiedperforatedflaps and computations using the body force model. It is found that the effective porosity of the surface is affected by flow separation within the perforations. Theflowblockage of the separation regions is primarily a function of the angle to the freestreamand the ratio of the thickness to hole diameter. Accordingly, a formulation for the body force model is proposed that incorporates this finding. The resulting velocity field is in good agreement with the experiments and with the direct computations.


In the paper not only is the importance of construction claims to engineering constractor illustrated, but also the factors of claims, forms of counter claims and the ways of solution to claims and counter claims are discussed.


Audio description (AD) is an accessibility resource designed to improve access for blind or low vision individuals by describing images, narrating actions and visual elements, such as scene details, some aspects of the character (eg, age, gender, clothing), among others. However, in general, an AD is only generated in sections of the video that do not contain dialogue. This is done to prevent any overlap with the dialogue in the video, which may hinder the user's understanding rather than helping it. Thus, one of the first steps in the AD generation process is to identify the speechless intervals, which are candidates to receive AD. In this work, we present a solution for automatic identification of speechless intervals in digital videos using Convolutional Neural Networks (CNNs). Our proposal is to automate this step in the AD generation process, reducing the time and effort involved for generating AD. Another alternative would be to integrate it into an automatic or semi-automatic audio description generation system. The results shows that, considering a minimum confidence level of 0.5 for the output of the classification model, the solution obtained a balanced average accuracy of 93% to identify speechless segments considering all the videos tested.


Purpose: The rat meniscal injury (MNX) model of osteoarthritis (OA) resembles changes observed in human tibiofemoral OA such as cartilage damage,osteophyte formation and angiogenesis,both in the synovium and at the osteochondral junction.With its mild to moderate severity and a time course of 5 weeks it provides a suitable disease model to explore factors that may either exacerbate or relieve OA.The angiogenesis inhibitor PPI2458 is an irreversible inhibitor of the enzyme methionine aminopeptidase (MetAP)-2.It exerts its anti-angiogenic potential by arresting endothelial cells in the G1 phase of the cell cycle thereby inhibiting their proliferation.We set out to determine whether angiogenesis inhibition using PPI-2458 reduces pain and osteoarthritic structural changes in the MNX model of OA. Methods: OA pathology was induced by transecting the meniscus in male Lewis rats (n = 8 per group,weight = 300g) on day 0.Treatment with PPI-2458 (5mg/kg,orally,every other day) or vehicle control was given from day 11 to 34.Naïve animals were used as the baseline controls.On day 35,synovia were harvested and snap frozen.Knee joints were fixed in neutral buffered formalin or Zamboni's fixative overnight and decalcified prior to being cut in coronal sections.Joints were then wax embedded or frozen in OCT.Tissue sections were cut and stained with haematoxylin and eosin to assess tissue architecture.Sensory nerves were immunolocalised using antibody to the neuropeptide calcitonin gene-related peptide (CGRP).CD31 positive cells and PCNA immunoreactive CD31 positive cells were detected to identify endothelial cells and proliferating endothelial cells respectively in the synovia as two separate measures of the extent of angiogenesis.Macrophage infiltration was identified by immunoreactivity for the monoclonal antibody clone ED1.Computer-assisted image analysis was used to quantify proliferating endothelial cell index and macrophage fractional area.Pain behaviour [Incapacitance:difference in weight bearing (g) between the hind paws (right-left)] and joint swelling (knee diameter) were measured from before surgery until day 35. Results: Meniscal injury increased pain behaviour in the operated animals compared to naïve controls 12 days after surgery and this difference was maintained until day 35.Increased joint swelling,cartilage damage,osteophytes and osteochondral angiogenesis were observed in the MNX operated animals 35 days after surgery with increased synovial inflammation and angiogenesis compared to naïve controls.Sensory nerves were located in the osteophytes,synovium and in the subchondral bone,adjacent to blood vessels.Angiogenesis inhibitor PPI-2458 reduced weight-bearing assymetry in the MNX model by day 19 compared to vehicle treated animals [25g (95% CI,19 to 31), 46g (95% CI,37 to 55),P<0.01] and maintained this reduction to day 35 [24g (95% CI,19 to 29), 47g (95% CI,37 to 57),P<0.001].Pain behaviour however was not completely abolished to naïve levels.Joint swelling was reduced with PPI-2458 to naïve levels in the MNX model 14 days after surgery [0.2mm (95% CI,0.01 to 0.2),


Sound quality evaluation in the context of product sound quality has been addressed and investigated on hand-held power tools. Out of those, power drills, hand-held circular saws and jigsaws have been chosen as the products of interest. A series of listening tests has been conducted in order to ascertain how people perceive not only the sound emitted by these devices in operation, but also certain properties of the devices themselves, such as their quality, safety of handling, robustness, proper functioning and others. The values of objective parameters describing the sounds of these devices were obtained. Well known parameters such as loudness, sharpness and roughness were used, and certain new parameters were defined. Linear regression models were made for subjective parameters describing the perception of the devices using relevant objective parameters as an attempt to model the subjective grades obtained through listening tests and to predict such grades for future products to be included in the investigation. Based on individual parameters, a single-number overall grade was defined.


FIELD: personal use articles. SUBSTANCE: ironing board comprises a base (1), a body (5) with a working surface, and a device for height adjustment, adjusting the distance between the body and the base. The rack (7) passes between the body and the base, it has a stationary frame (31) attached to the base, and a movable frame (33), attached to the body. To reduce the force required to adjust the height of the body relating to the base, the device for height adjustment includes a means of application repulsive force between the body and the base. The closure device of the rack includes a multi-stage gear transmission (45) and the locking device (43). The gear transmission is attached to one of the frames. The locking device is attached to another frame and is removably installed on this gear transmission. The system includes such an ironing board and an iron. EFFECT: improved usability of adjustment the height of the ironing board and improved regulation safety. 11 cl, 20 dwg