The case of a 26 year old woman who had been taking tranexamic acid to prevent uterine bleeding due to an IUD and who died from thrombosis of the left internal carotid artery is reported. The patient's father had died at age 54 of myocardial infarction. Otherwise the family history was entirely negative for thromboembolic disease. The patient was a mild smoker. She had been previously healthy and in particular, she was not affected with hypertension, diabetes, or dyslipidemia. She had carried to term 2 uncomplicated pregnancies. 40 days prior to hospital admission her gynecologist had inserted an IUD. The insertion of the IUD was followed by persistent uterine bleeding, and for this reason she began treatment with tranexamic acid (1.5 g/daily). Uterine bleeding persisted despite this treatment, and the IUD was removed. Because of persistence of a mild uterine bleeding, tranexamic acid was continued. 2 hours before admission the patient suddenly presented a left sided hemiparesis with disarthria and vomiting. On admission she was stuporous. The left side of her face drooped and the strength of the left arm and leg was markedly decreased. Both arm and leg reflexes were symmetrical. Her blood pressure was 110/70. An electroencephalogram on arrival confirmed a right sided cerebral lesion. Subsequently the patient's condition deteriorated rapidly. She developed a full left hemiplegia and became deeply comatose. A CAT scan performed 4 hours after admission showed no abnormalities. A CAT scan performed 3 days after admission showed a large cerebral infarction involving nearly the whole right cerebral hemisphere. The patient's condition remained essentially unchanged until she died 6 days after admission. Permission for autopsy was refused. Antifibrinolytic drugs competitively inhibit plasminogen activators and noncompetitively plasmin. Thromboembolic complications after the administration of antifibrinolytic drugs have long been recognized. The use of IUDs is often associated with troublesome uterine bleeding and particularly excessive menstrual bleeding. To avoid these complaints, antifibrinolytic drugs are increasingly used.


Resveratrol is antioxidant of polyphenol class that can counteract free radials of UV causing premature aging. Resveratrol also works by lowering the transcription factor of Activator protein 1 (AP-1) and nuclear factor of kappa beta (Nf-kB) that plays a role in the pathogenesis of skin aging. Resveratrol is water-insoluble and light-sensitive (Amri et al, 2012). Therefore, to overcome the obstacles of resveratrol active substance stability for topical antioxidant preparation, it is necessary to design a delivery system that can effectively protect antioxidant and also support the working mechanism of the antioxidant. In this study, resveratrol was made in NLC delivery system with various comparisons of solid lipid and liquid lipid matrix to obsevere its effect on characteristics, effectiveness on penetration and collagen density in vivo, as well as stability test of 30-day storage at room temparture (pH, particle size and polydispersity index). The measurement of pH was using pHmeter, viscosity was using cone and viscometer plate, particle size and polydispersity were using Delsa Nano Particle Size Analyzer, particle morphology was using Transmission Electrone Microscopy (TEM) and trapping effectiveness was using centrifugation method which then seen using UV spectrophotometer at 306nm. The determination of penetration effectiveness was performed in vivo using male mouse back sking with Rhodamin B marker observed using fluorescence microscope at 2nd, 4th, and 6th hours. The effectiveness on antiaging was performed using the male mouse back skin treated for 28 days, after which preparations were performed to be observed with light microscope and the collagen density was calculated based on histopathology scoring.


Influences of coal preparation on hazardous air pollution materials (HAPM) in terms of their distribution and occurring mode were studied on the basis of data from experiments and on-site coal preparation plants. The study showed that current coal preparation technologies could significantly reduce HAPM concentrations in coal, and hazardous trace elements removal could be improved by decreasing upper limit of the feeding granularity.


A calcium binding protein with a molecular mass of 40 kDa (CBP40), the gene product of plasmodial-specific LAV1-2 of Physarum polycephalum, was crystallized in the presence of EDTA. The crystals diffracted X-rays up to a resolution of 3.0 A. They belonged to the trigonal space group, P3221 (or P3121), with unit cell dimensions of a = b = 64.4 A and c = 207.2 A. Ca2+-bound crystals were obtained by soaking in a CaCl2 solution, which gave diffraction data of similar quality. The Ca2+-soaked crystals belonged to the same space group as those crystallized in the presence of EDTA with unit cell dimensions of a = b = 64.4 A and c = 209.4 A.


The purpose of this study is to analyze the effect of the concept of optimal distinctive open innovation as mediating variable in relationship between Person-Job Fit and Person-Organization Fit and work innovation behavior and lecturer performance. The method used in this study are through Structural Equation Modeling (SEM) analysis with the object of the study conducted on 193 lecturers determined by purposive random sampling technique at private universities in Central Java. The findings showed significant effects of person-organization fit on the optimal distinctive open innovation and on innovative work behavior. Moreover, person-job fit is of significant on optimal distinctive open innovation, and on innovative work behavior. In testing the effect of mediating variables, optimal distinctive open innovation is of significant on innovative work behavior which in turn affecting the significant influence of innovative work behavior on lecturer performance. The findings emphasize that the success-oriented way of thinking requires the expertise of employees to always create creative, superior and unique ideas. Private universities must always pay attention to the principles of industrial management and professionalism in human resource management, in order to survive and develop. Superior skills will produce superior performance, and superior skills are distinctive competence that supports the company to achieve positional advantage.


High core loss is the most outstanding problem in high speed permanent magnet motors. To solve this problem, water cooling or oil cooling is usually adopted, which increase the complexity and cost. Considering the characters of high permeability, high resistivity, low loss and low cost for soft magnetic ferrite, this paper proposes a novel high speed PM motor based on soft magnetic ferrite. Soft magnetic ferrite ring is used as stator core, rare earth PM ring serves as the rotor poles, and the slotless configuration with long effective air gap is adopted. The size matching design between the stator magnetic ring and the PM magnetic ring can make themselves work in their best operating points respectively, lower core loss and higher power density will be ensured in the motor. The results of magnetic field analysis, core loss analysis and the prototype test prove that the core loss can be greatly reduced, which verifies that the high speed PM BLDC motor based on soft magnetic ferrite is feasible.


Through summarizing research of documentaries and forward-looking analysis,this paper discusses the characteristics of the sports animation and its promotion of China's sports industry,and points out its outstanding performance in the popularity of sports,increasing sports funs,sports teaching and research.The rapid development of sports animation must lead sports industry in China to a higher level.


The improvement of interpretation expertise has gone through the development stage from novice to expert. In the developmental process of expert interpreters, the key is to enhance the interpretation expertise through deliberate practice. Deliberate practice is a concept firstly put forward by Ericsson to answer the question of how genius excels. This paper discusses how to better the mental representation and adaptive mechanism of novice by introducing the IPTAM system, a collab·orative interpretation learning platform. IPTAM (Interpreter Professional Training and Acquisition Module) for short. It is a modular interactive Online interpreting learning platform.


Objective: The COVID‐19 pandemic has led to greater societal divides based on alignment with vaccine mandates and social distancing requirements. This paper briefly lays out the experiences of individuals in Aotearoa New Zealand related to public health messaging.


A study was performed to determine the biological half-life and plasma concentrations of gentamicin in gopher snakes. The snake plasma was assayed for gentamicin, using a microbiological agar well diffusion technique. In the 1st study, 10 gopher snakes (groups A and B) were each given a single injection of gentamicin. They were anesthetized and samples of blood were collected each day to determine the antibiotic half-life. The average half-life was 82 hours (SD = 31) at an environmental temperature of 24 C. The variations in the results were probably due to metabolic differences within individual snakes. In another study, 11 gopher snakes were treated with serial injections of gentamicin for about 2 weeks. Group C snakes were given gentamicin at a dose level of 2.5 mg/kg of body weight/72 hours, and those in group D were given a dose level of 2.5 mg/kg of body weight/day. Group E snakes were given gentamicin at a dose level of 5.0 mg/kg of body weight/72 hours, and group F snakes were given gentamicin at a dose level of 5.0 mg/kg of body weight/day. The snakes given gentamicin each day reached very high antibiotic concentrations in their plasma. With the long half-life of gen-


Background: The GTPase Ran is the key regulator of nucleocytoplasmic transport. Results: RanGDP is modified with SUMO1 by the E3 ligase RanBP2 and deSUMOylated by the isopeptidase SENP1. Conclusion: Ran is subject to reversible sumoylation at nuclear pore complexes. Significance: SUMOylation of Ran might be a novel way of regulating the directionality of nucleocytoplasmic transport for certain cargoes. The SUMO E3 ligase complex RanBP2/RanGAP1*SUMO1/Ubc9 localizes at cytoplasmic nuclear pore complex (NPC) filaments and is a docking site in nucleocytoplasmic transport. RanBP2 has four Ran binding domains (RBDs), two of which flank RanBP2's E3 ligase region. We thus wondered whether the small GTPase Ran is a target for RanBP2-dependent sumoylation. Indeed, Ran is sumoylated both by a reconstituted and the endogenous RanBP2 complex in semi-permeabilized cells. Generic inhibition of SUMO isopeptidases or depletion of the SUMO isopeptidase SENP1 enhances sumoylation of Ran in semi-permeabilized cells. As Ran is typically associated with transport receptors, we tested the influence of Crm1, Imp β, Transportin, and NTF2 on Ran sumoylation. Surprisingly, all inhibited Ran sumoylation. Mapping Ran sumoylation sites revealed that transport receptors may simply block access of the E2-conjugating enzyme Ubc9, however the acceptor lysines are perfectly accessible in Ran/NTF2 complexes. Isothermal titration calorimetry revealed that NTF2 prevents sumoylation by reducing RanGDP's affinity to RanBP2's RBDs to undetectable levels. Taken together, our findings indicate that RanGDP and not RanGTP is the physiological target for the RanBP2 SUMO E3 ligase complex. Recognition requires interaction of Ran with RanBP2's RBDs, which is prevented by the transport factor NTF2.


A magnetoacoustic electric core-current controlled analog/digital memory, with nondestructive readout, using torqued metallic-glass tape cores, is reported. Memory control is achieved by the magnitude and polarity of a galvanic current through the core. A model for the magnetization is presented.


Dear Editor, Topical lidocaine is used in many dermatological procedures and several transdermal patches can be used with no harmful systemic side effects. However, very rare reports are available on systemic adverse reaction of topical lidocaine during dermatological procedures, especially cardiac toxicity. In case of any adverse cardiovascular reaction, cardiopulmonary resuscitation (CPR) is the last resort to save a person's life during cardiac arrest. Complications and injuries caused by CPR are well described and recognized in previous studies. Herein, we describe a 64-year-old woman who developed cardiac arrest after topical administration of lidocaine during microneedling procedure, and further progressed to a sublethal aortic injuries due to CPR procedure. A 64-year-old woman developed cardiac arrests after applying topical lidocaine cream (2.5%) for microneedling which was applied 1 h before the procedure and accompanied by massaging the face and neck. The volume applied was in concordance with previous guidelines to form a thick layer under occlusion. She had no previous history of ischemic heart disease (IHD). After cardiac arrest in the office, resident physician immediately initiated manual CPR; then, she was taken to Modarres Hospital (Tehran, Iran). When transferred to the hospital, the patient had a cardiac arrest and underwent CPR again. CPR was being performed again in the hospital for 30 min and then she was intubated. The initial evaluation revealed normal electrocardiogram, cardiac enzyme and serum electrolytes. Echocardiography revealed LV dysfunction after CPR. The next day, the patient became extubated, but she developed a fever of 39 (accompanied by Leukocytosis of 14 000 per μL), distal sensory-motor weakness, and paresthesia. She underwent a Brain CT-scan and Brain MRI according to the neurological consultation. Next, a small old hemorrhage was seen in the sub-occipital region on both sides but did not explain the patient's symptoms. The patient was treated with intravenous Vancomycin (1 g/q12hr) and Meropenem (1 g/q8hr) antibiotics for 5 days due to the fever. Echocardiography was performed again and revealed normal LV and RV size and function, mild LV diastolic dysfunction, and mild tricuspid regurgitation. Ten days after the completion of a course of antibiotics, fever was recorded again (ESR = 100, CRP = 3+). Thus, chest CT-scan was performed according to the infectious consultation, which revealed bilateral parenchymal lower lobe aspiration pneumonia; thus, antibiotics was again prescribed for a week (Vancomycin 1 g/q12hr, Amoxicillin clavulanic acid 500 mg/125 mg q8hr, and Azithromycin 500 mg/day). As the patient reported mild chest pain during admission before being intubated, ECG and cardiac enzyme assessment were performed which revealed normal result. Hence, she underwent noninvasive CT angiography due to the aborted sudden cardiac death for coronary evaluation. The test revealed normal coronary artery, but surprisingly intramural hematoma of the thoracic descending aorta was observed (Figure 1). CT angiography of aorta was reperformed 7 days later to confirm previous CT reports. The size of intramural hematoma increased by 25% (Figure 1). Thoracic Endovascular Aortic Repair (TEVAR) was performed via bilateral accessory femoral artery to treat intramural hematoma. The TEVAR device was placed from below the left subclavian to above the diaphragm. The patient was followed with CT-scan after 4 days that reported well seated and patent aortic stent-graft without residual flow. The patient's condition was completely normal (Figure 2). One month after hospitalization, patient was discharged in good general condition and on medication order (Tablet ASA 80 mg/day, Tablet Atorvastatin 40 mg/day, Tablet Furosemide 20 mg/bid, Tablet Carvedilol 6.25 mg/bid, and Tablet Cloxacillin 500 mg/qid). Two weeks later, she referred to the Heart Clinic and she was in acceptable condition without any complaints. To our knowledge, this is the first case of cardiac arrest during a cosmetic procedure after topical lidocaine application. Neurotoxicity has been reported in previous reports but none of them reported cardiac toxicity after topical skin application of lidocaine. A review by Tran et al showed that topical lidocaine might also accompany systemic reaction. Previous report also indicated a case of lidocaine toxicity after the application of lidocaine 30% gel followed by laser therapy. Although the absorption of lidocaine has been reported to be minimal during skin administration, we could observe a catastrophic reaction after its application during microneedling. Also, previous reports showed that the chronicity of application and the nature of skin lesion may play a crucial role in systemic toxicity. It has been shown that injured epidermis, dressing, and increased dosage of lidocaine would increase the absorption of drug. As lidocaine acts by binding voltage-gated sodium channels, the inhibition of action potential can be a possible explanation for cardiotoxicity. On top of that, inhibiting myocardial cellular respiration was mentioned as another possible mechanism. Morteza Safi and Isa Khaheshi have contributed equally and also considered as first authors. Received: 30 August 2020 Revised: 8 October 2020 Accepted: 11 October 2020


Ad26.COV2.S boosts antibody and T-cell responses following BNT162b2 vaccination Sho Iketani*, Lihong Liu*, Manoj S. Nair , Abishek Chandrashekar, Hiroshi Mohri, Maple Wang, Dan H. Barouch, Yaoxing Huang and David D. Ho Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Massachusetts Consortium on Pathogen Readiness, Boston, MA, USA; Division of Infectious Diseases, Department of Internal Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA


The subject of the study is the results of the study by domestic researchers of the history of the formation and development of the objects of the shipbuilding base of the Baltic Fleet during the Peter the Great era. The aim of the work is to analyze the works of Russian scientists-historians of the pre-revolutionary, Soviet and post-Soviet periods on this problem and to form on this basis a holistic view of the formation and development at the initial stage of one of the most important branches of the domestic military industry. In the course of the study, the main attention will be paid to the consistent consideration of the history of the origin, the specifics of the organization and maintenance of activities, as well as the results of the activities of all shipyards that worked in the interests of the Baltic Fleet during the designated period. The research methodology is based on a combination of general philosophical, general scientific historical and special historical methods, such as analysis and synthesis, modeling, problem-chronological and perspective analysis method. The novelty of the conducted research lies in the fact that such an approach to the study of the initial stage of the history of the shipbuilding industry in the interests of the Baltic Fleet has not been applied in Russian historiography. According to the results of the study, a generalized picture of all shipbuilding enterprises established in the Peter the Great era in the north-western region of Russia and in the territories of the Baltic States and Finland conquered during the Northern War is presented. The results of the study allowed us to assess the nature of the formation of the industry as mainly spontaneous, although not devoid of a certain logic in the specific historical conditions of the Northern War. Certain patterns of placement of certain objects of shipbuilding infrastructure, the influence of geographical, hydrographic, production-logical and other features on their specialization are shown. A problematic issue requiring further study is formulated.


Roland Barthes is one of the most well-known semioticians outside academic circles. That knowledge is sometimes based on misconceptions about his theory of signs, extrapolated from Saussure. This article will offer an outline of Roland Barthes' sign theory, demonstrating the ways that it is derived and adapted from Saussure and how Saussure is refracted through Barthes' readings of other linguists. It will look in particular at Barthes' innovations in sign theory: denotation, connotation and metalanguage, as well as his extension of linguistic thinking to analyse nonverbal modes. It will also discuss Barthes' notion of 'myth' and its influence as a concept. The article will consider a number of instances from media and cultural studies where Barthes' interpretations have not only given subsequent uses of sign theory license to speculate beyond Saussure's original linguistic bearing but have also unwittingly contributed to the stagnation of semiotic analysis.


PURPOSE
We determine the value of dynamic sentinel node biopsy for staging squamous cell carcinoma of the penis.

MATERIALS AND METHODS
During a period of 2 years 17 patients with penile cancer was performed after lymphoscintigraphy pre and intraoperatively with gamma ray detection probe at biopsy of the sentinel node with the aid of perilesional administered patent blue dye. After 20 days regional lymph node dissection was performed in all patients.

RESULTS
Sentinel node metastasis was found in 5 patients; in one case lymphoscintigraphy not visualized sentinel node. All negative node biopsy was confirmed with the regional lymph node dissection. No major complication did occur after sentinel node biopsy.

CONCLUSIONS
Occult lymph node metastases can be detected by dynamic sentinel node biopsy including preoperative lymphoscintigraphy, vital dye and gamma ray detection probe with a sensitivity of 78%, predictive negative value of 100% and with low morbidity.


Abstract High resolution X-ray photoelectron spectra have been obtained for two planar aromatic bis-disulfides : tetrathionaphthalene (Fig. 1, N° 1) and tetrathiotetracene (Fig. 1, N° 2).


We do not know yet how large the economic damage of this pandemic will be. But under plausible scenarios, government support to the economy will be in the double digits as a percentage of national incomes. How can such amounts be financed, without sparking a second sovereign debt crisis in the weaker euro area countries? The ECB's new Pandemic Emergency Purchase Programme (PEPP), launched last week, has bought precious time. But PEPP is mainly designed to reduce liquidity strains and avoid an immediate run on the debt of highly indebted euro area countries. Some of the financing needs will be absorbed by the monetary expansion implied by PEPP. But allowing for only temporary deviations from the capital keys in the ECB asset purchases could limit the extent of the monetary support to the highly indebted countries. More needs to be done. We must find alternative financial arrangements that shield the euro area against a return to 2011-like crises.


The growing trend towards the exchange of data between heterogeneous objects and platforms have increased the level of complexity in the Internet of Things (IoT) area. Beyond those, to enable seamless resource sharing between different IoT systems, efforts by academia and industry have currently focused on achieving semantic interoperability between IoT platforms. That involves the delivery of dynamic interaction between platforms to interconnect the variety of smart objects covering both multiple technologies and intelligent services. With this in mind, the main goal of this work is to propose a mechanism to validate and achieve interoperability between IoT platforms. A motivating example is described and analyzed along with the implementation of the proposed system.


Sustained release dosage forms containing the active ingredient blended with the polymer matrix. At least a portion of the polymer matrix is formed from a cellulose ether, the cellulose ether starting melting temperature of at least 40 ℃, with anhydroglucose units linked by a 1-4-linked, and has a methyl, hydroxy alkyl group, and optionally an alkyl group as a substituent different from methyl, such that the cellulose ether MS (hydroxyalkyl) of 0.05 to 1.00, and hydroxy anhydroglucose unit substituted with methyl, such that [s23 / s26 -0.2 * MS (hydroxyalkyl)] is 0.31 or less, where s23 is the mole fraction of the anhydroglucose units of the following, only the anhydroglucose units wherein the 2- and 3-positions of the two hydroxyl groups methyl substituted, where s26 is the mole fraction of the anhydroglucose units of the following, wherein only the anhydroglucose units of the 2- and 6-position by a methyl group substituted with two hydroxyl groups.


Extracts from various medicinal mushrooms (Lentinus edodes, Grifola frondosa, and Coriolus (Trametes) versicolor), and particularly their proper blends, are of significant interest in selecting the best of them for treatment, or even prevention, of different pathological aberrations, including cancer. In this study, mushroom preparation effects on the proliferation of tumors and normal cells, respectively, as well as the survival rate of the mice with transplanted tumors, were determined. The incorporation of radioactive 3H thymidine in tumor cells (mouse squamous cell carcinoma [SCCVII], fibrosarcoma [FsaR], and melanoma [B16F10]) was inhibited in the presence of particular mushroom preparations. The effect was dose dependent and was different for tumor cell cultures used. On the other hand, the incorporation of radioactive 3H thymidine in normal Chinese hamster lung fibroblasts (V79 cell) increased, and the effect was generally dose dependent. The application of mushroom preparation to the mice bearing either SCCVII or FsaR tumor could influence their survival. On day 30 after SCCVII tumor cell transplantation, there was a 20% survival rate of mice in the control group, but 60-80% survived if particular mushroom extracts were applied. There were no survivors in the control group on the 36th day, but 40-60% were alive in the experimental groups. Furthermore, there was a 60% survival rate for mice with FsaR tumor when treated with mushroom preparations and a 20% survival rate in the control group on day 36 after tumor cell transplantation.Thus, the findings that the mushroom preparation tested induced a selective inhibition of tumor cell proliferation observed in vitro and a pronounced prolongation of the survival rate of tumor-bearing mice are of particular interest. These findings, together with the data that these compounds are not toxic to the organism, deserve further attention.


The total expenditure of funds, federal and otherwise, for research and development will continue to rise in 1967, although, the rate of in crease will be less than the 12 percent annual average for the last decade and even less than the eight percent increase last year. Even so, expendi tures will reach approximately $24 billion this year. W hat happens to the results from these expenditures? Are they too immature for use? Are they so technically complicated that there will be difficulty in communi cating them to others? Are they being "put" to use? These questions are frequently being asked by research sponsors and consequently there is a growing feeling that more direct methods of getting research into practice are needed. The distribution made of these funds with respect to how much is actually being spent on research provides background as to the magni tude of the problem. In 1965 for example, 23 percent of the funds went to research and 77 percent to development. Of the 23 percent, four per cent was used in basic research and 19 percent in applied research. It is the applied research, or mission-aimed research, with which we need to be especially concerned. That is, what happens to those research results emanating from the expenditure of approximately five billion dollars. (1)(**)


Objective To investigate the mechanism of increase of the blood-tumor barrier(BTB) permeability by overexpressed miR-34a.Methods After transfecting human brain capillary endothelial cell line NKIM-6 with miR34a mimic,real-time PCR analysis was used to detect the expressing level of miR-34a.The NKIM-6 cells overexpressing miR-34a and human U87 glioma cells were used to establish the BTB model in vitro.Transendothelial electrical resistance(TEER) of BTB was measured and the expressing levels of tight junction associated proteins ZO-1 and claudin-5 in NKIM-6 cells were detected by western blot and immunofluorescence staining.Results After transfection with miR-34a mimic,the expressing level of miR-34a in NKIM-6 cells raised up markedly,the TEER of BTB decreased significantly.In the NKIM-6 cells of BTB in vitro,the expressing levels of tight junction associated proteins ZO-1 and claudin-5 were reduced significantly,ZO-1 and claudin-5 positive products showed a discontinuous localization on the membrane of NKIM-6 cells.Conclusion Overexpression of miR-34a increased the BTB permeability significantly,and the down-regulated expression of tight junction associated proteins might be one of the related mechanisms.


The nature of low productivity of CBM well experiences represent low interflow performace over matrix and fractures in coal bed. Therefore, to increase CBM well production rate, it is necessary to improve the interflow performace. An approach to improve the interflow performance is to find out the possibility of increasing gas flowrate in carbon bed taken into account factors dominantly effect on the performance. For this purposes, Variable Pressure Wave Cycles Hypothetical Model has been developed based on Pressure-Swing adsorption - desorption (PSA) technique commonly applies in natural gas separation using carbon active bed. Preliminary simulation of the model has been carried out using data related to carbon bed taken from previous studies. Variables in the simulation are kinetic constant and hypothetic pressure waves generated which is required to increase gas flow rate in the bed. The simulation results demonstrate the possibility of interflow performance improvement in carbon bed. However, this improvement is asymptotically limited to maximum amount of gas desorbed from carbon bed as well as Langmuir Isotherm pattern application for gas desorption from coal. Moreover, the simulation of the model shows the sensitivity of gas interflow performance to hypothetical pressure waves generated and kinetics controlling adsorption/desorption mechanism and mass transport in carbon bed.


**This work was supported financially by MCYT of Spain (projects CTQ2006-05367/BQU and CTQ2009-08464/BQU to M.C.), by the U.S. NIH (grant GM38767 to L.Q.), and by the Italian MIUR (Prin project to L.L.). I.G.B and A.C. thank MICINN for PhD grants. M.T.-S. thanks the CSIC for the JAE-DOC contract. We thank STR-UdG for technical support. M.C. also thanks the Generalitat Catalunya for an ICREA-Academia award and for project 2009 SGR-637.


Great place to begin business research. Learn how to research business topics. Here are a few things to keep in mind.


In this work, we present a low-latency partition tolerant distributed ledger using a novel directed acyclic graph (DAG) structure. By forcing information to be published at specific deterministic locations, we avoid complex consensus algorithms and eliminate confirmation periods. We implement our DAG over a fully decentralized overlay network, leveraging BitTorrent concepts for peer-to-peer (P2P) rendezvous and block propagation. We compute overall expected latency using Erd¨os-R´enyi random graph models and present initial proof-of-concept software. The resulting work will allow anyone to create fully decentralized services (records, databases, etc.) resistant to attack, manipulation, and censorship.


Inthis article, the relationship between the social, economic, cultural and politicaldemands of the masses and the religious policy of the Democratic Party isdiscussed in terms of the practices on religious education in the multi-partydemocratic phase in Turkey which is accepted as one of the most importantturning points in Turkish political history. During the period of Democratic Partygovernment, relatively more "reasonable" and non-coercive managementapproach, dominated the political process and the state waivered of theextreme applications of secularism in the bureaucracy and everyday life. Alsothe needs and habits of the broad sections of the people, which is regardedas freedom of religion and conscience, shaped the policies. However all thesedemocratic achievements, during the period of multi party democratic phase, apopulist policy tradition was shaped. In terms of this attitude, the traditionalistconservative opposition in Turkey was seen as a vote potential by participatingpolitic parties in the competition. Thus, in order to gain the political support ofthis sector, religion was politicized by these politic actors.


A key issue in the two-path successive relaying (TPSR) communications systems is the interference, which is caused by the concurrent transmission of the source and one of two relays. The previously reported investigations show that interference cancellation is required at the relays and destination to avoid severe performance degradation. In this work, we introduce a different approach that does not require interference compensation for decode-and-forward TPSR systems, while maintaining diversity gain and full rate. At the listening relay, the proposed approach enables the separation between the source and the forwarding relay transmissions by using two carriers of the same frequency but in phase quadrature. Therefore, a maximum-likelihood data detector can be adopted without being interfered by the inter-relay link. At the destination node, we make use of the interference signal to develop optimal and sub-optimal data detectors. Furthermore, we derive a theoretical lower bound on the bit-error-rate performance. Simulation and analytical results demonstrate the superiority of the proposed approach compared to the conventional schemes reported in the literature.


Tin can be determined in the range 3 to 3000 p.p.m. by molecular-band emission from the SnH species in a nitrogen-hydrogen diffusion flame. The emission at 609·5 nm, which is almost line-like, gives a limit of detection of 1·5 p.p.m. of tin. Spectral interference from sodium is eliminated by use of a didymium filter. The presence of oxygen gives rise to a much broader spectrum, caused by tin(II) oxide formation, with a visual limit of detection of 5 p.p.m. of tin. Atomic emission can be observed only in the presence of alcohols, e.g., isopropyl alcohol, but a high concentration of ground-state tin atoms exists in the diffusion flame. Mechanisms are discussed to explain the production of tin atoms, SnH and the resonance-line emission.


Background: Oman is a Middle Eastern country bordering the Arabian Sea, Sea of Oman and the Persian Gulf. It has a population of about four million people, about 50% of whom are expatriates. The WHO report is the first international assessment of Oman's health system (HS). More, the WHO report is the first-ever comprehensive assessment of the world's health systems. Purpose of the study : To discuss the WHO report assessment of Oman's health system. In addition, we will explore how a small country with relatively a young health system could, achieve such a high ranking where others with high financial capacity and well mature health system fail to achieve a goo ranking by the WHO standard. Methods: The study utilises WHO report that relies on the following major components: (1) goal attainment (effectiveness), (2) health expenditures per-capita, and (3) efficiency and the overall level of health performance. Its analysis identifies the key outcomes in terms of three main goals for HS: to improve health; to improve the responsiveness of the HS to people's legitimate expectations of being treated with dignity and autonomy and due care; and to encourage, the third component, the HS to be fairly financed. Results: Oman was ranked highly by the WHO report. Its success is very impressive compared to many countries that are well advanced and have a better health finance system. WHO used five performance indicators to measure HS in 191 member states, it finds that France provides the best overall health care followed among major countries by Italy, Spain, Oman, Austria and Japan. Conclusions, brief summary and potential implications: This highly innovative study has been criticised for its choice of objectives and advocate a case for omitting the equity of financing from the list and replacing it with an index of access, both financial and geographical. The weights attached to the system objectives have not been validated. However, it is highly unlikely that a single set of weights or a single set of objectives can be obtained which are valid reflections of the aspirations of every country in the world. Key words : World Health Organization, health report, health system, Oman, health system, effectiveness, health expenditures, efficiency, health performance, dignity and autonomy.


developing a mobile application that enables users to browse through a list of voicemail messages and personal greetings; select and play them, and in the case of greetings record them, in a user friendly GUI environment. The product is called "myGreetinq Mobile".


This paper deals with the role of ICT in Croatian small enterprises. Small enterprises are one of the most important initiators of overall economic development. ICT plays an important role in the current economy. Small enterprises need to take advantage of the power of ICT in order to take on the competition. The paper follows the research based on the questionnaire as data gathering method. The paper highlights the number of computers, connection to the Internet, evidence of formal education, financing of education costs, ICT certificates, budget for the investment in ICT, planning of ICT system development, security and prevention of ICT risks, the benefits of ICT use and the obstacles to ITC implementation.


The Hausdorff distance (HD) between two point sets is widely used in similarity measures, but the high computational cost of HD algorithms restrict their practical use. In this paper, we analyze the time complexity to compute an accurate Hausdorff distance and find that reducing the iterations of the inner loop significantly contributes in reducing the average time cost. Based on the observation that the nearest neighbor (NN) of the breakpoint in the current inner loop suggests a higher probability to break the next inner loop, we present a novel and efficient approach for computing the accurate Hausdorff distance based on a diffusion search. The current breakpoint is recorded as the diffusion center of the next inner loop so that the efficiency of the HD computation can be significantly improved without scanning every point. According to the type of 3-D model (sparse and dense point sets), a novel HD computation framework consisting of two specific diffusion search methods is proposed. First, a Z-order-based HD algorithm (ZHD) for a sparse point sets is proposed. Second, to avoid the low efficiency of a diffusion search when computing the Hausdorff distance between dense point sets with the ZHD algorithm, an octree-based HD algorithm (OHD) is proposed. Evaluation results demonstrate that the ZHD algorithm and the OHD algorithm can greatly reduce the time complexity of HD computations for sparse and dense point sets, respectively. In addition, we conduct several comparative experiments against the most famous HD computation methods. Experimental results show that the proposed approach achieves performance as good as the most efficient available algorithm and exhibits better performance in dealing with spatial data that is highly overlapping.


Objective To investigate the single hole in video-assisted thoracoscopic operation(single-port VATS)for treatment of pulmonary diseases operation operation method and clinical application.Methods From 2010 January to 2012 January our department used single hole in video-assisted thoracoscopic operation for treatment of spontaneous pneumothorax in 24 cases,incision for an operation hole and an observation hole.Anterior lateral intercostal incision group(control group)for treatment of spontaneous pneumothorax in 22 cases,with fourth or fifth intercostal space10~15cm anterolateral small incision.Results Local excision of lesion had an average operation time of 35(30~60)min,average bleeding volume of 45(15~60)ml,without blood transfusion;the average postoperative hospital stay was 4.8days(4~7).The whole group of patients were stable,and no serious complications.Conclusion The single operating hole of video-assisted thoracoscopic surgery can be used in the treatment of spontaneous pneumothorax with strong indications.


The surge of hostility to Jews and the Jewish State in the Polish media and politics in early 2018 took many observers by surprise. For some, it was shocking to witness a virtual tidal wave of antisemitism in the mainstream discourse of one of the largest member states of the European Union—on territory which, during the German occupation, was the epicenter of the Holocaust. It was also a great shock because for many years, bilateral relations between Poland and Israel had been especially cordial and fruitful.


We evidence experimentally the convective and absolute instabilities in an optical system. In our system, the presence of noise and spatial non‐uniformities (as in most of the "real systems") add additional complexities. First we derive analytical expressions of both thresholds for the ideal noiseless and spatially uniform situation. Then numerical simulations allow to determine signatures of those instabilities. The corresponding noise sustained and dynamical patterns are observed experimentally in a liquid crystal layer subjected to a laser beam with tilted feedback.


In Rushmore et al., there was an error that affected the phylogenetic analysis presented in Figure 2. Below is a corrected version of Figure 2, which includes sequences from fecal and urine samples obtained from chimpanzees in our study and other related parasites (with Genbank accession numbers). Full-length (250 ±1 nt) Illumina reads from fecal samples were paired by name and merged using Geneious R9 (Kearse et al., 2012). The resulting 25 unique sequences with TFR-primer sequences were retained. Sequences from urine were acquired using traditional cloning methods from a subset of urine samples (N = 16 samples) instead of Illumina due to trace contaminants among the Illumina reads. We used uclust (Edgar, 2010) implemented in MacQIIME to consolidate sequences with >97% similarity into operational taxonomic units (OTUs) which resulted in three fecal OTUs and five urine OTUs. All sequences were aligned using Geneious alignment with default settings. Phylogenetic reconstruction was performed in Mega7 (Kumar, Stecher, & Tamura, 2016) (Fig. 2). The centroid sequence from each OTU was submitted to Genbank (accession numbers KX017526-KX017533).


Sidoarjo mudflow or known as Lapindo mudflow erupted since 2006. The Sidoarjo mudflow is located in Sidoarjo City, East Java, Indonesia. The mudflow-affected area has high air pollution level and high health risk. Therefore, in this paper was implemented a system that can categorize the level of air pollution into several categories. The air quality index can be categorized using fuzzy logic algorithm based on the concentration of air pollutant parameters in the mudflow-affected area. Furthermore, Dataflow programming is used to process the fuzzy logic algorithm. Based on the result, the measurement accuracy of the air quality index in the mudflow-affected area has an accuracy rate of 93.92% in Siring Barat, 93.34% in Mindi, and 95.96% in Jatirejo. The methane concentration is passes the standard quality even though the air quality index is safe. Hence, the area is indicated into Hazardous level. In addition, Mindi has highest and stable methane concentration. It means that Mindi has high-risk air pollution.


Real-time and precise morphological analysis of intraoperative AAA is a significant pre-imperative for robot-assisted minimally invasive surgery (RMIS). However, this task is frequently accompanied by the difficulties of ambiguous boundaries and obscured surfaces of aneurysms. To remedy these problems, we propose a Light-Weight Dual-Stream Boundary-Aware Network (DSB-Net) and a novel diagnosis algorithm for real-time morphological analysis of AAA. In the network, the features at the boundaries are preserved by incorporating a boundary localization stream, while the interior segmentation accuracy is guaranteed with a mask prediction stream. Moreover, the diagnosis algorithm is developed to measure the exact size of AAA. Quantitative and qualitative assessments on two different types of datasets illustrate that (1) The presented DSB-Net remarkably outperforms the other previously proposed medical networks with the inference rate of 10.8 FPS, which meets the real-time clinical necessities. (2) The developed algorithm provides accurate size measurements for AAA, which indicates the proposed approach can be integrated into the robotic navigation framework for RMIS.


The main goal of a coal mine safety system is to be built using things that speak as the data transmission channel. In coal mines, the system monitors and manages a variety of parameters, including light detection, gas leak detection, temperature and humidity conditions, and coal mine fire detection. These sensors are bundled together and put in coal mines. Thing Speak receives and analyses all sensor values in real-time. The gas is monitored regularly here, and if there are any concerns about the gas level, a bell is used to alert the workers. In this configuration, an LDR sensor detects the presence of light. The light comes on automatically and may be controlled using the LED button. An alert notification is sent to the authorized person's mailbox if a fire breaks out in a coal mine. Temperature and humidity levels are regularly checked and displayed on the serial monitor and the thing talk platform. The developed technology is primarily utilized to improve coal mine working conditions and protect workers' safety.


At the present time, the only established method of metering a pulsating fluid flow involves the installation of damping devices in the system between the source of pulsation and the flow meter to ensure that the flow through the meter is essentially steady. Such devices may comprise a combination of frictional and volumetric damping and the method by which the required degree of damping is determined makes use of the Hodgson criterion. In many systems, it is undesirable (or, at least, inconvenient) to have to incorporate this damping and, therefore, the more direct approach, involving the metering of flow which is actually pulsating, is of considerable practical interest. In the present note, the various factors affecting the metering errors in pulsating flow are discussed in relation to the results of an experimental investigation into the pulsating flow of air through a number of standard orifice configurations.


This investigation aimed to analyze the perceptions of young practitioners of Olympic and Paralympic modalities about the development of life skills through sport, according to sex, age group and time of practice. The sample included 147 young athletes from Olympic (n = 57) and Paralympic (n = 90) modalities, with an average age of 13.14 ± 1.37 years and practice time of 7.35 ± 4.83 years. The instruments used were: a sociodemographic questionnaire and the Life Skills Scale for Sport (P-LSSS). Data analysis was performed using the Kolmogorov-Smirnov tests, independent t and Pearson correlation (p <0.05). The most experienced practitioners obtained higher values in the dimensions of leadership and communication (p <0.05). When comparing the sexes, the boys obtained a greater perception of learning in the variables: goal setting, social skills and emotional skills (p <0.05). When comparing the modalities, Olympic sports athletes showed significant differences in teamwork, problem solving, emotional skills, leadership, time control and communication (p <0.05). It is concluded, based on the conception of young athletes, that sport can contribute to the learning of positive characteristics, with sports practice in the long run being one of the possible factors that result in the success of this process.


Life Story Work (LSW) is an intervention primarily used with care-experienced young people to help them produce a coherent, co-produced life narrative. The intervention has been in circulation since the 1960s, yet it has still been vastly under-researched. This article examines two models of LSW in circulation in the UK today and concludes that each model has its advantages and limitations. However, more research into the outcomes of LSW is needed. The article offers an autoethnographic case study of the author's own experience of LSW and its potential outcomes to help inspire more researchers examine this vital intervention for a young person's development.


This article discusses differences between men's and women's perception of the family. The Family Environmental Scale (FES) was administered to over 900 individuals from different groups with diffe...


Linear-chain conditional random fields (LCCRFs) have been successfully applied in many structured prediction tasks. Many previous extensions, e.g. replacing local factors by neural networks, are computationally demanding. In this paper, we extend conventional LC-CRFs by replacing the local factors with sum-product networks, i.e. a promising new deep architecture allowing for exact and efficient inference. The proposed local factors can be interpreted as an extension of Gaussian mixture models (GMMs). Thus, we provide a powerful alternative to LC-CRFs extended by GMMs. In extensive experiments, we achieved performance competitive to state-ofthe-art methods in phone classification and optical character recognition tasks.


In this paper the results of several years of research in the field of positioning capabilities analysis of surface ships are illustrated. The developments refer to station-keeping, dynamic positioning and track-keeping. As regards station-keeping a predictional methodology is presented which provides, given the environmental forces and the configuration of the positioning system, the minimum-power setting of the propulsive and steering devices on the basis of a numerical optimisation technique. This methodology is used in the preliminary design of a positioning system and in the realisation of a joystick system to support manoeuvring operations at low speed. As regards dynamic positioning a computational procedure is described for real time simulations of an automatically controlled vessel in wind, waves and currents. This methodology is applied to evaluate wither the performances of automatic control systems or the positioning capabilities of dynamically controlled vessels. As regards track-keeping, an implementation of the dynamic positioning procedure is described, used to study the approach manoeuvres in restricted waters of autopiloted ships.


1 Whole‐cell patch‐clamp recordings were made from rostral ventrolateral medulla (RVLM) neurones of brainstem slices from 8‐ to 12‐day‐old rats. In the presence of tetrodotoxin (0·5 μM), 5‐HT (50 μM) elicited an outward current (I5‐HT,outward) (10/44 neurones) associated with an increase in membrane conductance, and an inward current (I5‐HT,inward) (29/44 neurones) accompanied by a decrease or no significant change in membrane conductance. 2 The steady‐state I‐V relationship of I5‐HT,outward showed an inward rectification; the 5‐HT‐induced current, which reversed at ‐87·9 ± 3·0 mV, was suppressed by 0·1 mM Ba2+. 3 Two types of steady‐state I‐V relationship for I5‐HT,inward were noted: type I I5‐HT,inward was characterized by a significant decrease in membrane conductance and reversed at a potential close to or negative to the theoretical K+ equilibrium potential (EK), ‐94 mV, in 8/17 neurones; type II I5‐HT,inward was not associated with a significant change in membrane conductance and was relatively independent of membrane potential. 4 Both type I and type II I5‐HT,inward were significantly reduced in a low [Na+]o solution. In this solution, I5‐HT,inward decreased with hyperpolarization and had a linear steady‐state I‐V relationship with a reversal potential of approximately ‐110 mV. The reversal potential of type I I5‐HT,inward shifted to about ‐80 mV as the [K+]o was increased from 3·1 to 7·0 mM in low [Na+]o solution. The type II I5‐HT,inward did not reverse at the estimated EK in the same solution. 5 While not affected by externally applied Cs+ (1 mM), I5‐HT,inward was significantly smaller in RVLM neurones patched with Cs+‐containing electrodes; the current reversed at ‐11·9 ± 6·4 mV in 8/15 responsive neurones. 6 It may be concluded that in rat RVLM neurones 5‐HT increases an inwardly rectifying K+ conductance which may underlie the I5‐HT,outward and that a combination of varying degrees of K+ conductance decrease and a Cs+‐insensitive, non‐selective cation conductance increase may account for the two types of conductance change associated with I5‐HT,inward.


In the present work analytical preparations are being made based on the study of the asymptotic behaviour for the scattering amplitude of Higgs bosons in the ladder approximation for the purpose of further investigation of the Higgs boson decay into a pair of Z 0-boson in the large-momentum. To formulate the computational model in the ladder approximation, the Bethe-Salpeter equation with a minimal perturbative kernel is used. An asymptotic solution of the above equation is obtained at high energies.


Five fluorescent dyes (BASO Red 546, Brilliant Sulfaflavine, Fluorescein, Uvitex OB, and Rhodamine B) and
seven non–fluorescent dyes (Amaranth, Reactive Black 5, Patent Blue Violet, Tartrazine, Lissamine Green B, Erythrosin B,
and Ponceau 4R) were tested to determine their potential in tracer application for spray deposit assessment. Laboratory
experiments were performed to determine the tracer recovery rate from paper targets, either kept in the dark or exposed to
sunlight. Tartrazine was easily extractable and relatively photostable and was chosen for further evaluation on different
targets (paper, Mylar, and vine leaves), either sprayed or manually treated. Tartrazine was considered suitable for deposit
assessment from agricultural sprayers because of no toxicity, simple laboratory procedure, high recovery rate, and relatively
low photodegradation. However, field experiments should be properly planned to reduce, or to account for, variability of
natural targets (variable extraction rate and possible background deposits) and photodegradation under exposure to sunlight.


This paper investigates the distributed cross polarization ratio (CPR), which is relevant for scanning arrays and distributed sources such as those found in mobile communications. The maximum and average (over angle) CPRs are computed over different angular intervals, which represent either the scan sector of an array, or the target directions for the distributed gain of a fixed antenna. The results show that the best polarization purity is achieved with an optimum ring source radius of about lambda/4, which corresponds to an optimum value of the substrate relative permittivity in a circular patch antenna


These Ecole polytechnique federale de Lausanne EPFL, n° 1497 (1996) Reference doi:10.5075/epfl-thesis-1497Print copy in library catalog Record created on 2005-03-16, modified on 2016-08-08


Article history: Received 30 July 2015 Received in revised form 18 May 2016 Accepted 5 June 2016 Available online xxxx This paper presents findings from a nationally representative household survey on the tendency to regret purchases across 20 product groups. The survey reveals that the vast majority of adults in Great Britain (82%) have regretted a purchase in the past. Post-purchase regret is shown to be particularly prevalent for clothing & footwear and takeaway food. The tendency to regret purchases appears to reduce with age and to bemore common amongst white collar rather than blue collar workers. Combining survey results with average price estimates gives an estimated, aggregate, annual expenditure on regretted purchases of £5–25bn, equivalent to 2– 10% of annual consumer spending on goods in Great Britain. These findings are interesting because they suggest that there is a degree of self-assessed over-consumption that, if reduced, could help to reduce pressures on the environment. © 2016 Published by Elsevier B.V.


The diffusion process of electrons and holes which have been pumped into a metastable band in bismuth films by a 1.064‐μm laser pulse is considered in the calculation of the induced thermal gradient. The fit between the temporal evolution of this calculated thermal gradient and that of the thermoelectric response of films to the laser excitation allows us to estimate an upper limit of the ambipolar diffusion coefficient of metastable carriers.


This article examines the structure underlying the vote in the 2004 presidential election. Specifically the study uses correlation and factor analysis to discern the extent to which the structure of the vote in 2004 was similar to that of prior elections. The analysis reveals that the structure of the state-by-state vote in 2004 demonstrated a remarkably high level of continuity with recent presidential elections. Indeed at the aggregate level, the stability exhibited in the presidential vote now rivals that found during the zenith of the New Deal party system. This suggests that those who continue to talk about dealignment and ongoing electoral volatility have missed an important development in the contemporary American party system: the stability underlying the presidential vote not only in 2004 but over the past three decades of party competition.


Wear indicator system vehicle tires. wear indicator vehicle tires, applicable to any kind of tire and for any type of vehicle system, characterized in that the tread (2) of any type of tire (1) has two layers (3), (4), differentiated by different colors, with the color of the outer layer (3) the standard of said tire, while the color of the inner layer (4) having the depth of tread to which the tire should be changed, a color noticeably different from the previous, so that once the outer layer (3) of the tread (2) is worn, the inner layer (4) of the same of a different color appears, indicating at a glance the necessity of changing the tire wear it (Fig. 4).


The use of doxorubicin, an antineoplastic medication used for the treatment of cancers via mechanisms that prevent replication of cells or lead to their death, can result in damage to healthy cells as well as malignant. Among the affected cells are mesenchymal stem cells (MSCs), which are involved in the maintenance and repair of tissues in the body. This review explores the mechanisms of biological effects and damage attributed to doxorubicin on MSCs. The PubMed database was used as a source of literature for this review.


A low-cost Al-doped ZnO (AZO) thin film was deposited by radio-frequency magnetron sputtering with different Ar/O2 flow ratios. The optical and electrical properties of an AZO film were investigated. A highly conductive AZO film was inserted between the amorphous InGaZnO (a-IGZO) channel and the metal Al electrode to form a heterojunction source/drain contact, and bottom-gate amorphous a-IGZO thin-film transistors (TFTs) with a high κ HfON gate dielectric were fabricated. The AZO film reduced the source/drain contact resistivity down to 79 Ω cm. Enhanced device performance of a-IGZO TFT with Al/AZO bi-layer S/D electrodes (W/L = 500/40 µm) was achieved with a saturation mobility of 13.7 cm2 V−1 s−1, a threshold voltage of 0.6 V, an on-off current ratio of 4.7 × 106, and a subthreshold gate voltage swing of 0.25 V dec−1. It demonstrated the potential application of the AZO film as a promising S/D contact material for the fabrication of the high performance TFTs.


In this paper, the advantages of using an interferometric method for detecting and characterizing icebergs in sea ice were demonstrated. Iceberg topography was analyzed using single-pass TanDEM-X interferometric synthetic aperture radar (InSAR) data. Multiple InSAR data sets in bistatic mode were acquired over icebergs in sea ice in the Arctic region. InSAR processing was used to extract 3-D elevation information of the sea ice surface. The results firmly demonstrate the capability of TanDEM-X data to characterize the shape of icebergs. Very high resolution (VHR) optical satellite data were collected by Pleiades 1A over the same area to derive digital elevation models (DEMs) of ice features for validation. The accuracy of the extracted topography over icebergs was evaluated by comparing InSAR and optical DEMs. The quantitative comparison demonstrated good correspondence between InSAR and optical DEMs with root-mean-square value values of 2.2 m for icebergs and 0.6 m for sea ice, respectively. Using DEMs derived from VHR optical imagery, it was possible to calculate receiver operating characteristics (ROC) for detecting icebergs in sea using InSAR. The resulting ROC analysis illustrates a good detection performance.


As engine technology developed continuously, engine with both turbocharging and
 EGR has been researched due to its benefit on improving the engine efficiency.
 Nevertheless, a technical issue has raised up while utilizing both turbocharging
 and EGR at the same time: excess condensed water existed in intake manifold
 which potentially trigger misfire conditions. In order to investigate the
 root-cause, a CFD model (conducted by CONVERGE CFD software) was presented and
 studied in this paper which virtually regenerated intake manifold flow-field
 with EGR condensed water inside. Based on the simulated results, it concluded
 that different initial conditions of EGR condensed water could significantly
 change the amount of water which deposited in each cylinder. Thus, a coefficient
 of variation of deposited condensed water amount among these cylinders, was
 marked as the evaluation reference of cylinder misfire. Theoretically, as this
 coefficient of variation reduced, the EGR condensed water from intake manifold
 would be distributed homogeneously in each cylinder, and thus less possibility
 of cylinder misfire should be observed. As concluded from the presented multiple
 simulated results, the coefficient of variation of deposited condensed water
 amount was above 30% statically for the existing intake manifold, which meant
 the existing intake manifold had tremendous room for optimization. The result
 showed that the fluctuation of the inner surface of the intake manifold had a
 great impact on the flow of condensate water, so different surface shapes could
 be designed in the intake manifold to organize the flow of condensate water, so
 as to make the condensate water of each cylinder more uniform, and reduce the
 occurrence of fire.


The changes of characteristic volatile compositions of'Okubo'peach and ethylene release rate,as well as relevant enzyme activities stored at ambient temperature after harvest were studied.The impact of grass-type aroma reduction to flavor is greater than that of floral aroma increase;Taking the ratio of grass-type aroma to floral aroma as a indicator,the flavor is the best when the ratio is minimum.The ethylene release rate was significantly negative correlated with the aldehydes content and grass-type aroma content.The ACO and the LOX enzyme co-regulate the ethylene synthesis,thereby control the release of volatile compositions and affect fruit flavor.


Background: testicular lymphoma constitutes between 1 and 9 % of testicular tumors; it is the most frequent malignant testicular tumor in men over 50 years of age. The prognosis is reserved due to a great tendency to early systemic spread. The most common clinical presentation is testicular pain on palpation and spontaneous, with increased volume and testicular consistency. Its treatment is based on three fundamental pillars: orchiectomy, chemotherapy and radiotherapy. Objective: to describe a patient with large cell type B testicular lymphoma. Case report: 55-year-old male patient, hypertensive, smoker 10 cigarettes a day, occasional drinker. He goes to consultation due to left testicular volume increase. In the laboratory tests, the lactate dehydrogenase is elevated. Ultrasound Scand: Left testicle with very heterogeneous echogenicity, unstructured parenchyma, no nodular lesions. Diffuse thickening of the epididymis. Increased vascularization. Inguinal radical orchiectomy is performed, the anatomic-pathological diagnosis being diffuse large B cell type lymphoma, it has now been treated with chemotherapy, because he alsopresented bone involvement. But he has evolved favorably. Conclusions: testicular lymphoma is a very rare entity, despite being considered the most common testicular tumor in people over 60 years of age. The majority are diffuse non-Hodgkin lymphomas of high intermediate degree of malignancy and immune-phenotype B. The prognosis is always reserved due to its great tendency to systemic spread. The treatment is based on surgery (radical inguinal orchiectomy), chemotherapy and radiotherapy. DeCS: TESTICULAR NEOPLASMS/surgery; TESTICULAR NEOPLASMS/radiotherapy; LYMPHOMA, LARGE B-CELL, DIFFUSE/diagnosis; ORCHIECTOMY/methods; ANTINEOPLASTIC AGENTS /therapeutic use.


t he 5th annual ISHRS meeting had begun with 2 days of presentations delivering instructive, innovative and controversial information (see Barcelona Report-Part I in the previous issue of the Forum.) Day three of the conference featured an International Forum of speakers from around the world describing new technology and regional trends in hair replacement surgery. There were a number of interesting highlights. From down-under, Russell Knudsen spoke of transplanting hair in graded areas of density, rather than broad areas of uniform density, to produce added naturalness in appearance. Richard Shiell described refined closure methods for donor sites. Mario Marzola, speaking on Megasessions Made Easy and Practical, has reached


This paper introduces construction ideology and distinguishing features in the Experimental Teaching Center of Mineral Processing in Central South University.The center replans its laboratory and divides it into different function areas according to branches of learning,which achieves the fusion of subjects and resource sharing,forms an experimental platform for innovative talent cultivation.Meanwhile,it develops the advantage of interdisciplinary fusion in the reform of experimental teaching and establishes its new system.It fuses national scientific research achievement into experimental teaching,and combines the training of engineering practical abilities with real scientific research projects.This forms a benign interaction and plays a positive and exemplary role.


Investigations were carried out on 9 dogs with an isolated Pavlov stomach, a fistula of the stomach and of the duct of the parotid gland. In eight dogs a stereotype of conditioned reflexes with acid reirforcement was elaborated. Raw meat served as the food stimulant. Functional weakening of the cerebral cortex was produced by application of a supersonic sound stimulant (rattle). The dogs were subjected to general roentgen irradiation with a dose of 350 r. Disorders of the higher nervous activity and of the secretory function of the gastric glands were observed in the course of acute radiation sickness. The higher nervous activity and the secretory function of the gastric glands in dogs with functional weakening of the cerebral cortex were characterized by deeper and longer lasting changes.


Identification of the species that promotes the growth of silicon dioxide on silicon in a microwave oxygen plasma has been investigated. Comparison of ion analysis experiments using quadropole mass spectrometry and oxide growth experiments performed in the same system indicates a strong correlation between the oxide growth and the presence of O− ions in the plasma.


The invention discloses a process for extracting unsaturated fatty acid and polypeptide in peanuts, which comprises the following steps of: pressing and filtering peanuts after baking, peeling and crashing to obtain crude oil and peanut pulp; filtering the obtain crude oil to remove impurities; then carrying out saponification, crystallization, acidification reaction; and washing and separating to obtain the high-purity peanut unsaturated fatty acid. Another process comprises the steps of: basifying degreased peanut pulp after soaking to extract protein components from the peanut pulp; and hydrolyzing the protein components by using prolease to obtain peanut polypeptide. By making full use of raw materials, the two most important active components in peanuts: peanut oil and peanut protein, are obtained, and further reactions are carried out on the peanut oil and the peanut protein to remove components useless to human health to obtain the peanut unsaturated fatty acid and the peanut polypeptide, therefore the application value of the raw materials is enhanced.


This article analyzes the role of intercultural communication in cyberterrorism. Cyberspace is a common site of meeting and interaction between cyberterrorists from multiple cultural backgrounds. It is also a place where cyberterrorists have to face law enforcement agents. As a result, intercultural clashes sometimes occur. This justifies the necessity for better understanding intercultural communication in Internet-mediated situations. Although there have been published pieces on hackers' culture, this article breaks new ground partly because no literature review has produced work on the role of intercultural communication in cyberterrorism.


The web is having a significant impact on how firms interact with each other and their customers. Past stumbling blocks for supply chain integration such as high transaction costs between partners, poor information availability, and the challenges of managing complex interfaces between functional organizations are all dissolving on the web. In this paper, we examine how the web is changing supply chain management. We present a survey of emerging research on the impact of e-business on supply chain management including descriptive frameworks, analytical models, empirical analysis, and case studies. We classify the work into three major categories: e-Commerce, e-Procurement, and e-Collaboration.


Background  Hypogonadism in Prader–Willi syndrome (PWS) is generally attributed to hypothalamic dysfunction or to primary gonadal defect, but pathophysiology is still unclear.


The effective g factor g* of conduction electrons in degenerate CdTe has been determined by using measurements of the Cd nuclear spin-lattice relaxation time T& and the Knight shift JC. It is shown that the magnitude of g* is given by the Korringa product TfTK = C(g*)2, where C is a known constant and T is the absolute temperature, and that the sign of g* is given by the sign of E for a spherically symmetric conduction band. The measured value, g~= — 1. 1+0. 1, is within the range allowed by effective-mass theory. Also, the electronic probability density at the nucleus, normalized to unity in an atomic volume, is calculated to be )g&'. (0) [ =6. 5&&10 cm, about 70% of that found for the free Cd ion in a 5s Sf/2 state. I'0 ground state Vleck paramagnetism From an analysis of the susceptibility, information about the Sm-Sm exchange interactions is obtained. The deduced variation of this exchange with lattice parameter is shown to be consistent with the pressure dependence of the susceptibilities. Electron resonance of Eu@, Gd, and Mn2' present as dilute impurities has also been observed. The are subject to large shifts (nearly 50% for Mn ' in SmS) due to the im-purity-host lattice interaction; to deduce the Sm-impurity exchange interactions. found that the Eu-Sm and Sm-Sm interactions are nearly identical in each lattice and furthermore that they follow the same systematic trend as the Eu-Eu exchange in the corresponding europium chalcogenides. The magnitude however is much larger in the Sm lattice, directly reflecting the closer proximity of the conduction band. The Gd-Sm exchange interaction is roughly twice as large as that found for Eu-Sm in each host lattice. This increase in exchange in going from the larger Eu2' ion to the smaller isoelectronic Gd+ ion im-plies that the extra electron accompanying the Gd+ ion plays an active role in the exchange process. The Mn-Sm interactions are found to be of opposite sign (antiferromagnetic} and approximately four times larger than those for Eu-Sm.


Three principal facies of sedimentation in the Tertiary of the Maracaibo basin, Venezuela, are differentiated and correlated. Cretaceous sedimentation is also discussed briefly.


Particular features of gapped core current transformers and characteristics of transient phenomena inside them are under consideration; a procedure is proposed that allows for evaluating the excitation limiting e.m.f. and overall dimensions of the CT required for installation, based on known parameters of the transient conditions in CT installation point and the specified CT error.


A rapidly changing environment requires new thinking by strategic leadership – intangible competences must be cultivated. Suggests this is best approached through partnership between universities and corporations in the design of applied management research projects. Describes the creation of the International Consortium for Executive Development Research with this end in mind.


I consider three challenges to the traditional view according to which moral responsibility involves an epistemic condition in addition to a freedom condition. The first challenge holds that if a person performs an action A freely, then she thereby knows that she is doing A. The epistemic condition is thus built into the freedom condition. The second challenge contends that no epistemic condition is required for moral responsibility, since a person may be blameworthy for an action that she did not know was wrong. The third challenge invokes the quality of will view. On this view, a person is blameworthy for a wrong action just in case the action manifests a bad quality of will. The blameworthy person need not satisfy an additional epistemic condition. I will argue that contrary to appearances, none of these challenges succeeds. Hence, moral responsibility does require a non-superfluous epistemic condition.


Key technologies for near-field recording/readout systems using a solid immersion lens (SIL) are summarized in this paper. Our system employing a SIL of 1.84 numerical aperture (NA) and a laser diode (LD) of 405 nm wavelength has realized the capacity of a 112 GB in a 12 cm diameter phase-change disc along with a write-power margin of ±11.2% and a data transfer rate of 36 Mbps. Such a larger-capacity data storage system should provide a high data transfer rate. A preliminary result of 1.84 NA dual-channel near-field recording/readout using a monolithic dual-beam LD with 412 nm wavelength is presented.


This paper focuses on the development of television media in Pakistan, its role and impact, mode of function and nature of programmes designed to impart knowledge and information to the masses.


With the development of the more large-scale, complex and diversiform civil engineering structures, the problem of choice of structural styles (CSS) has become more and more important In this paper, some key scientific problems are discussed, which include: the position of CSS in the whole life-time optimization of engineering and structural optimization, the knowledge acquisition and representation of CSS, the knowledge inference of CSS, the problem-solving of CSS and the building of intelligent design system for CSS


PELLETS COMPACTOS A given particle size are obtained from mixtures PRELIMINARY CONSTITUENTS MOSTLY SOLID AT LEAST OF AGENTS DETERGENTS AND CLEANING by adding plasticizers and / or lubricants water-soluble, water-dispersible emulsifiable in water. Premix is worked to form a homogeneous mass and extruded PRESSURES 25 200 BARAS THROUGH OPENINGS WITH MOLD DRILLED WHOSE WIDTH EQUALS DADO granule size. COMPACTOS extrudates are reduced to a granule size DADO. THE PROCESS IS SUITABLE FOR PRODUCING CONCENTRATED FOR AGENTS DETERGENTS AND CLEANING WITH domestic and industrial use pellet form very compact pourable THICK. Concentrates may be stored for long periods of time and not have a tendency to agglomerate.


Coronavirus disease 2019 (covid-19) is the most recent HCID (highly contagious infectious diseases) pandemic to hit the world. The respiratory disease (sars-cov-2) has been shown to spread from symptomatic patients through droplets and aerosols. Because of the closed environment and the use of high and low-speed handpieces, ultrasonic scalers, infection spreads even more easily in a dental setting. During these times, our priority should be inward to protect ourselves as well as the patients who need medical attention. Various methods for controlling infection transmission from aerosol-generating dental procedures are recommended to accomplish this. In light of the effect of oral health on the seriousness of the Covid 19 pandemic, and to protect ourselves financially during this pandemic it is critical to explain patients that we dentists are using the most up-to-date approaches to keep them safe by reducing the risk of them contracting the virus from the dental office in order to maximise the number of outpatients. And it is important to treat every patient as a Covid -19 infected person and take the appropriate precautions to ensure our safety while rendering dental treatment.


Although family caregiving among non-Hispanic Whites (NHW) has been studied extensively, relatively little is known about the caregiving experience in Mexican American (MA) families. This article compares 196 MA caregivers to 165 NHW caregivers and describes differences in the caregiving structure and caregiving experience. For caregiving structure, more MA caregivers were adult children even though the elder had a living spouse, MA caregivers provided less help, fewer MAs lived with elders, and MA elders had better functional abilities, in spite of having similar health problems to their NHW counterparts. For caregiving experience, MA caregivers had and used less social support, felt less social restriction and less change in elder-caregiver-family relationships, had poorer health, and evaluated their role performance better than NHW caregivers.


The present paper introduces all personnal and full process management method for the overhaul and revamp project in the No.3 Sintering Plant of WISCO and discusses and analyzes its characteristics and briefly describes the implementation process of this method as well as the practice of commissioning of new equipments. Better results have been achieved in the project.


Hiatal hernia (HH) has been found in a large number of people, but there has been no unified way to diagnose it. The aim of this study was to compare the diagnostic efficiency of X‐ray, endoscopy, and high‐resolution manometry (HRM) in the diagnosis of HH using surgical diagnosis of HH as the gold standard.


The weighted kappa statistic provides a measure of agreement κ w (scorer1, scorer2) between two scorers (scorer1 and scorer2) who classify observations into one of several groups or categories. The following description is adapted from reference (E1). Two scorers (scorer1 and scorer2) analyze a set of N observations by classifying each observation into one of g groups. This leads to a g × g-matrix n, the table of occurrences. A cell n ij represents the number of observations that have been classified as belonging to category i by scorer1 and to category j by scorer2. Depending on the particular situation to be investigated, a weight w ij between zero and 1 is given to each cell n ij. The weight w ij quantifies the degree of discrepancy between the two categories i and j. Cells on the diagonal of the table of occurrences n, corresponding to equal classification by both scorers, are given weights of 1; whereas cells n ij with highly different categories i and j receive weights w ij close to or equal to zero. The weights w ij given to the different cells n ij of this second-by-second table of occurrences are displayed in Table E1. Whereas weights w ij close to 1 indicate that the respective classes i and j are close, weights close to zero correspond to classes that are very different. On the one hand, the choice of this particular set of weights is motivated by the intention to penalize a missed apnea (weight zero) more severely than a missed hypopnea (weight 0.5) or than a respiratory event detected by both


This report discusses the principles of a 'sustainably safe' Dutch road network. A monofunctional categorization of the roads is used as a major element. The principles produce more concrete functional design requirements for the road network and its parts. The report also describes which data are required to arrive at the design and implementation of a 'sustainably safe' road network in a particular region. These are concerned with: (1) the road network; (2) the road function; (3) the traffic characteristics; (4) the road characteristics; (5) the actual road hazard; and (6) the costs associated with the measures to be taken. Insofar possible, it is also mentioned each time which party is able to supply the data.


We measured the hot electron production from short pulse laser plasma interactions using a fiber-array-based compact electron spectrometer that uses permanent magnets for electron energy dispersion and over 100 scintillating fibers coupled to a 1024 x 1024 pixel CCD as the detection system. This spectrometer has electron energy coverage from 10 keV to 60 MeV. The whole spectrometer is compact with dimensions of 8 inch x 7 inch x 4 inch. We performed systematic measurements of electron production on the ultra short pulse laser JanUSP (with pulse width less than 100 fs) at intensity range interest to Fast Ignition scheme from 10{sup 17} Wcm{sup -2} up to 10{sup 19} Wcm{sup -2} at Lawrence Livermore National laboratory. The electron distributions were obtained at various laser energies for different solid target materials and observation angles. We determined characteristic temperature of the escaped hot electrons at various incident laser intensity which is confirmed by theoretical simulations using the ZOHAL Particle-in-cell (PIC) code.


Robotic Canvas combines swarm robotics, human-robot interaction, and art. The project creates a robotic canvas using a swarm of decentralised robots that a human can interact with to paint. Beauty ...


This keynote address begins with a discussion of the difference between words and action, directed specifically to the practitioner's task of meeting the communication needs of children and youth with severe disabilities. Brief overviews of current perspectives and practices are provided, considering such areas as how communicative acts are defined and understood and the need for inclusionary environments that are rich in communication opportunities for individuals with severe disabilities. Specific problem areas are identified, including: the need for disseminating and implementing the extensive knowledge base on communication practices, the need for improved preservice and inservice training, and the need to match words with action. (Author) *********************************************************************** Reproductions supplied by EDRS are the best that can be made from the original document. *********************************************************************** Assuring Best Practices in Communication for Children and Youth with Severe Disabilities


First described as a novel stellate cell population in the spleen by Steinman and his colleagues, dendritic cells (DCs) have been demonstrated in all lymphoid tissues and most tissues of the reticulo-endothelial system.1–3 DCs are potent antigen-presenting cells (APCs),4–7 and have the capacity to amplify their antigen presentation in response to exogenous inflammatory products or endogenous danger signals.8,9 This maturation process includes the ability to migrate through the lymphatic system to T-cell rich areas of lymphoid organs in order to present antigen and stimulate T-cell proliferation. As DCs undergo this maturation process, they increase the presentation of those cell surface proteins involved in T-cell activation, including MHC Class II and co-stimulatory molecule (CD86 or B7) expression.4,9 DCs have been shown to play a key role in many diseases associated with defects in acquired immunity, including systemic inflammation and sepsis.10 Since DC maturation has been labeled the 'cornerstone' between the innate and adaptive immune systems,11 it is not surprising that regulation of DC activation and maturation


Apatites reveal specific physicochemical properties according to the substituted trace elements. Fluoridated apatites, which contribute to the caries prevention, show unexpected crystallinity phenomena in contrast to their solubility behavior. CO3apatites, which must be closely connected with susceptibility to caries, are main inorganic components of biological hard tissues. The composites of CO3apatites and collagen are expected as hard tissue biomaterials with excellent biocompatibility for therapeutic use.


Abstract Objective: To determine whether students acquired clinical skills as well in general practice as in hospital and whether there was any difference in the acquisition of specific skills in the two environments. Design: Randomised crossover trial. Subjects and setting: Annual intake of first year clinical students at one medical school. Intervention: A 10 week block of general internal medicine, one half taught in general practice, the other in hospital. Students started at random in one location and crossed over after five weeks. Outcome measures: Students' performance in two equivalent nine station objective structured clinical examinations administered at the mid and end points of the block: a direct comparison of the two groups' performance at five weeks; analysis of covariance, using their first examination scores as a covariate, to determine students' relative improvement over the second five weeks of their attachment. Results: 225 students rotated through the block; all took at least one examination and 208 (92%) took both. For the first half of the year there was no significant difference in the students' acquisition of clinical skills in the two environments; later, however, students taught in general practice improved slightly more than those taught in hospital (P=0.007). Conclusions: Students can learn clinical skills as well in general practice as in hospital; more work is needed to clarify where specific skills, knowledge, and attitudes are best learnt to allow rational planning of the undergraduate curriculum.


The far field acoustic spectra at 90deg to the downstream axis of some typical high speed jets are calculated from two different forms of Lilley s equation combined with some recent measurements of the relevant turbulent source function. These measurements, which were limited to a single point in a low Mach number flow, were extended to other conditions with the aid of a highly developed RANS calculation. The results are compared with experimental data over a range of Mach numbers. Both forms of the analogy lead to predictions that are in excellent agreement with the experimental data at subsonic Mach numbers. The agreement is also fairly good at supersonic speeds, but the data appears to be slightly contaminated by shock-associated noise in this case.


In the past years, more than 300 hairdressers have been reported to the mandatory accident insurance carriers as being suspected of having developed hairdressers asthma. Between 2001 and 2003, only 68 to 85 cases were confirmed as being caused or worsened by working as a hairdresser. Our study of more than 100 hairdressers from 2001 - 2005 has shown two age peaks for suspected cases. The first one in mostly young atopic hairdressers lies between 18 and 22 years. The second peak was determined to be between 3 8 and 45, comprising almost exclusively smokers with chronic bronchitis. Our results show that in most cases working in a salon does not cause asthma but that the inhalative exposure to numerous chemical substances increases symptoms and in a few cases leads to a progression of pre-existing bronchial hyperreactivity and asthma.


The argument in this paper is that surface should be understood neither as a merely structural, nor as a merely decorative aspect of building. Rather, the creation of surfaces (interior walls or façades and so on) organises a programme which allows for a reading of the space of architecture. The latter formulation—the space of architecture—has a double register. On the one hand, it refers to the specific architectural works, to particular buildings, and how they effect and affect the subject. On the other hand, it makes a broader, theoretical point about the way that architecture is conceived as an effect of the possibilities inherent in the materials used in the making of surfaces. The argument is advanced through an engagement with work by Borromini, Semper and Loos.


Luminol and f luorescein are chemicals commonly used for presumptive tests to visualize latent blood associated with a crime scene. A new chemical, BlueStar, is now available for the same pur- pose. Research has shown that luminol and f luorescein do not interfere with STR analysis but little research has been done to demonstrate the effect of BlueStar, if any, on DNA analysis. In this study, blood-stained carpets that had been sprayed with luminol, f luorescein, and BlueStar were swabbed and the swabs were submitted for STR analysis. Full profiles at the 13 core CODIS STR loci were obtained from swabs from each carpet, demonstrating that BlueStar, like luminol and f luorescein, does not inhibit STR analysis.


Diagnostic radiology is the main source of exposure of the population to man-made ionising radiation. The X-ray examinations of thoracal organs occupy the first place, particularly in childhood. To reduce the risk from exposure in diagnostic X-ray examinations, especially paediatric diagnostic, the knowledge of the absorbed doses in tissue is important. Long-term and highly statistical dose measurements on patients and various phantoms during thoracal diagnostics of children with various dosimetric systems were described in the literature. The aim of the recent work was to measure the skin doses during X-ray diagnostic of lung of children, first of all on the eyes, the thyroid gland and gonades with radiophotoluminescence glass (RPL) and thermoluminescence (TL) dosimeters. Eyes and thyroid are radiosensitive organs and they are in the primary beam during the diagnostic treatment. In addition to dosimetry measurements cytogenetically status of patients was investigated. In the study special attention was given for use of adequate protection devices. Radiation risks associated with paediatric patients may not be considered as trivial. The present data should be taken into adequate radiation protection during X-ray examination, although we expected very low doses. On the basis of the results some proposals for the protocol of X-ray diagnostic of thorax will be given.


This study examined the antecedents and the consequences of tour motivations. More specifically, this study proposed how two sub-dimensions of a country's image, such as the cognitive and the affective destination images, affect tour motivations. In addition, it was proposed that tour motivation helps to enhance tour quality and tour satisfaction. Lastly, this study examined the effect of tour quality the tour satisfaction on word-of-mouth. A total of 623 samples were employed in order to test the seven hypotheses. This study employed the AMOS program to conduct confirmatory factor analysis and structural equation modeling. The results of the data analysis showed that the cognitive and the affective destination images play an important role in the formation of the tour motivation. This study also found that tour motivation has a positive influence on tour quality. Additionally, the current study confirmed the effect of tour quality on tour satisfaction. Lastly, the influences of tour quality on tour satisfaction and word-of-mouth were identified.


In a bipartite graph, a "cross-free matching" or "fooling set" is a matching no two of whose edges induce a C_4. Dietzfelbinger, Hromkovi\v{c}, and Schnitger (1994) showed that the maximum cardinality of a cross-free matching is at most the square of the rank of the bipartite adjacency matrix of the graph (regardless of over which field the rank is computed), and asked, whether this bound can be improved.
We show that if the rank is taken in characteristic 2, then the bound is asymptotically tight. For other non-zero characteristic, we show that a stronger form of Dietzfelbinger et al.'s inequality (implicit in their proof) for weighted adjacency matrices is tight. We use cyclic matrices defined by a linear recurrence relation.


United States Geological Survey, Woods Hole, Massachusetts,Seismic Sound Sources,Litton,Brigade, Ministry Geology and Mineral Resources, China Geological Survey. Chief Scientists: Dave Nichols, Zhang Zai Chao. Geophysical data (multichannel) of field activity 87046 (F-1-87-CI) in Pearl River, China, South China Sea, North Pacific from 12/08/1987 to 12/14/1987, http://walrus.wr.usgs.gov/infobank/f/f187ci/html/f-1-87-ci.meta.html.


The rhodiola rosea injection for curing coronary heart disease and angina pectoris is characterized by that its main effective components are rhodiola saponin extracted and separated from Chinese medicinal material rhodiola rosea and tyrosol, and its pharmaceutical tests show that it possesses the actions of obviously improving acute myocardial ischemia and myocardiac infarction, obviously reducing serum creatine phosphokinase (CK) content, reducing myocardial damagte, expanding coronary vessel and reducing coronary resistance, and said invented medicine can be used for intravenous injectionor oral administration, and can obtain the good and durable therapeutic effect.


Primary frequency control in power systems is being challenged by the large-scale integration of inverter-based resources (IBRs) because they do not typically respond to frequency fluctuations. This paper suggests introducing new reserve products into the electricity market that provide incentive for IBRs to contribute to primary frequency control in ways that take advantage of their fast-acting capabilities. In addition to a Primary Frequency Response (PFR) reserve product, which accommodates standard droop control, we suggest introducing a Fast Frequency Response (FFR) reserve product, a reserve product for Virtual Inertia (VI), which is also known as synthetic inertia, and an inertia product. We adopt a reserve requirement that guarantees sufficient primary frequency response reserve to adequately arrest frequency decline in response to a large generator outage within a certain margin. We place this reserve requirement into a real-time co-optimization problem, derive prices for each product and analyze the incentives provided to IBRs.


A new synthesis of the linear heterocycle 4-chloro-1H-triazolo(4,5-g)quinoline by reduction of the novel compound 4-chloro-1H-triazolo(4,5-g)quinoline-1-oxide is reported. Treatment of the latter with hydrazine hydrate in ethanol in a sealed steel vessel in the presence or not of palladised charcoal, under various conditions of both time and temperature, afforded some derivatives of both ring reduction and ring construction.


The oxidation of iodide by 1-MHz continuous ultrasound and the sonoluminescence in water created by pulsed ultrasound were investigated in the pressure range from 0.7 to 3 bar. At low intensities, the chemical yield and the luminescence intensity decrease with increasing pressure. At higher intensities the yields increase moderately with increasing pressure. There is a critical intensity above which a steep decrease in the chemical and luminescence yields occurs. This critical intensity is strongly shifted to higher values with increasing pressure


This paper will explore both the ways in which the practices of self-care, specifically related to mental health, have emerged as responses to the increasingly precarious status of life after the economic shocks of the Global Financial Crisis (GFC), whilst also looking to the work of Silvia Federici and Kathi Weeks to propose models for immanent critique of these practices. Although it cannot be taken as a pure origin, post-GFC mental health discourse has increasingly seen mental health discussed as a form of resilience to precarity. Furthermore, practices of self-care, and psychological forms of treatment such as cognitive behavioural therapy (CBT) have become vehicles for the intensification of personal resilience in the face of systemic crisis. If self-care involves an inward looking and depoliticised subject, surely political emancipation lies elsewhere. The possibility of some alternative to our present state of affairs, where self-care increasingly appears as a form of 'voluntary servitude,' that is to say, a form of self-subjugation with serious political risks, must surely be taken as a continual project for those engaged in critical inquiry. Then again, to suggest that those engaging in self-care are simply reproducing neoliberal subjectivity would surely miss the ways in which such forms of self-preservation might appear as unavoidable for the individuals in question. Through an engagement with their work—and one that draws parallels between their strategic critiques of reproductive labour broadly speaking, and the more specific area of mental illness and neoliberal governmentality—the question of the "necessity" of self-care will be brought into alignment with the possibilities of its practicality.