This article proposes a SLAM algorithm referred to as RGBD-Sphere SLAM. The key innovation of this work is the prototypical system that demonstrates how formal models of 3D geometric shape and appearance can be transformed into generative classification models that detect and recognize these shapes. Object models are specified as shape programs in PSML; a custom-built procedural language for 3D object modeling. Classifiers for each PSML shape are created by simulating how instances of each shape manifest in real-world sensor data, e.g., color images and range images. The proposed RGBD-Sphere SLAM algorithm demonstrates a prototypical example of the system. Here, the PSML program specifies spherical 3D objects having diffuse surface albedos and distinct color appearances. A recognizer uses PSML models of each object's geometry and appearance to detect instances of these objects within streaming RGBD sensor data. The detected model parameters are then integrated into an RGBD SLAM algorithm; hence the name RGBD-Sphere SLAM. This article describes the PSML programs, the spherical detection and recognition algorithms used, and describes the impact this approach has for improving the performance of RGBD SLAM approaches by incorporating detected objects as landmarks. This is the first example of a prototypical system that externalizes the geometric and appearance modeling to a programming language from which a recognizer is created, and marks an important step towards enabling users to "program" their problem space and allow computers to transform the formal object models, as expressed in PSML, into customized classifiers suited for specific sensor suites, e.g., color imagery and depth imagery.


Objective:The volatile compounds from Pimpinella candolleana were studied.Method:Solid-phase micro-extraction(SPME) was used to extract the volatiles.The chemical constituents were analyzed by gas chromatography-mass spectrometry(GC-MS) coupled with Kovats index.Result:Twenty-eight compounds were sep-arated and 19 compounds were identified,representative of 86.23% of total volatile compounds.The main com-pounds were(S)-1-methyl-4-(5-methyl-1-methylene-4-hexenyl)-cyclohexene(48.83%) and 1-(1,5-dimethyl-4-hexenyl)-4-methyl-benzene(6.15%).Conclusion:The main compounds in P.candolleana were terpenes.


We start from a local and linear space-time relation between the electromagnetic excitation and the field strength. Then we study the generally covariant Fresnel surfaces for light rays and light waves. The metric and the connection of space-time are left unspecified. Accordingly, our framework is ideally suited for a search of possible violations of the Lorentz symmetry in the photon sector of the extended standard model. We discuss how the skewon part of the constitutive tensor, if suitably parametrized, influences the Fresnel surfaces and disturbs the light cones of vacuum electrodynamics. Conditions are specified that yield the reduction of the original quartic Fresnel surface to the double light cone structure (birefringence) and to the single light cone. Qualitatively, the effects of the real skewon field can be compared to those in absorbing material media. In contrast, the imaginary skewon field can be interpreted in terms of nonabsorbing media with natural optical activity and Faraday effects. The astrophysical data on gamma-ray bursts are used for deriving an upper limit for the magnitude of the skewon field.


Technical writing is a crucial skill for engineering students' effective written communication, which shapes and affects their professional careers. This study designs team-based learning (TBL) instructional modules that are integrated into an existing engineering laboratory curriculum and evaluates their feasibility and effectiveness in improving engineering students' technical writing skills. The data were collected from structured survey questions distributed to student participants and from the instructor's independent evaluation of students' lab reports. The effect of assigning a team leader on students' writing performances was also evaluated. Our results indicated that students who have received TBL modules perceive a greater improvement in their technical writing skills than those who did not. A strong correlation was found between students' perception and the instructor's evaluation of the students' technical writing skills. Assigning a team leader in TBL instructional modules has not played a significant role in improving engineering students' technical writing skills. The same happens with gender. Overall, utilization of TBL instructional modules can advance engineering students' technical writing skills.


A 92-year-old man with hypertension, chronic obstructive pulmonary disease (COPD), peptic ulcer disease and dementia presented to the emergency department with a 2-day history of abdominal pain in the left upper quadrant, distention, dry cough and intractable vomiting. On physical examination, the patient had epigastric tenderness and bowel sounds were reduced.


The current economic models which promote materialism, individualism and consumerism have led to a global crisis which requires a new economic paradigm. This paper contends that Buddhism contains within its doctrines a paradigm which is well equipped to provide a solution to this crisis, one based upon the Buddha's middle path.


We report the magnetic and transport properties of a new ternary intermetallic compound, CeRhSn3, using magnetic susceptibility, magnetization, specific heat, electrical resistivity, muon-spin relaxation (μSR) and neutron diffraction investigations. The dc magnetic susceptibility data reveal two magnetic phase transitions at 0.9 and 4 K. The overall behavior of dc susceptibility and magnetization indicates a ferrimagnetic-type phase transition near 4 K. The specific heat data also exhibit sharp λ-type anomalies at 1 and 4 K. The behavior of the specific heat anomaly under the application of a magnetic field suggests that the 1 K transition is probably related to a transition from a ferri- to a ferromagnetic state. The low temperature specific heat exhibits an enhanced Sommerfeld coefficient γ (∼100 mJ mol − 1 K − 2) due to the formation of a moderate heavy fermion state. The resistivity of CeRhSn3 demonstrates an interplay between the RKKY and Kondo interactions which is further modified by the presence of the crystal electric field. Interestingly, the resistivity of the nonmagnetic reference compound, LaRhSn3, is found to increase with decreasing temperature. Further, the onset of long-range magnetic order below 1 K is confirmed from our μSR study on CeRhSn3. However, the 4 K transition is not detected in the μSR and low temperature neutron diffraction data. Analysis of the dc magnetic susceptibility data within the framework of a two-sublattice model of ferrimagnetism supports the ferrimagnetic-type transition at 4 K in CeRhSn3. We have observed an unusual frequency dependence of the peak near 4 K in the ac susceptibility, which shows that the transition temperature shifts toward the lower temperature side with increasing frequency.


The prevalence of obstructive sleep apnea syndrome (OSAS) can be common for infants. Current gold standard for its diagnosis is nocturnal polysomnography (PSG) but this procedure can be complex to perform. Pulse transit time (PTT) shows potential to indicate abrupt blood pressure (BP) changes during upper airway obstruction. Objective of this study was to assess the capability of PTT to differentiate central from obstructive sleeping respiratory events. This study involved 4 infants with mean age of 7.8 ± 1.9months. 58 valid respiratory events free from motion artefacts were pre-scored by 2 blinded observers. PTT results were then evaluated against the corresponding PSG scorings. Tidal breathing varied with standard deviation (SD) of 5.13ms and maximal decrease of 3.57% from baseline. Obstructive events showed a mean change of 4.95% (p 0.05) change, with SD of 2.47ms and maximal decrease of 2.90% (p>0.05). PTT is able to categorise central and obstructive respiratory events accordingly. Furthermore, PTT has showed its sensitivity to monitor marginal BP fluctuations during tidal breathing. Hence, preliminary results suggest that PTT can be a valuable OSAS screening tool for infants.


Mobile agents are autonomous software entities that are able to migrate across different execution environments. Mobility and autonomy make permanent connections unnecessary. Mobile agents architecture can bring many potential benefits such as great flexibility and improved performance into distributed systems. Therefore, they are believed to be playing an important role in future electronic commerce systems. However, mobile agents also create many new security threats from malicious agents and hosts. Route protection is one of security problems mobile agents have to face. Itineraries may be viewed as an specification or plan of mobile agents movements. A community of mobile agents is considered to implement the movement plan correctly, if their observed behavior corresponds to the plan. In this paper, route protections of mobile agents existed are introduced and compared firstly. A conclusion can be made that a protocol based on nested encryptions is the best. After that, based on atomic encryptions and signatures, authors use Hash function to present a effective itinerary protection of mobile agents. And its security and computational overhead are analyzed in detail. The results show that the protocol satisfies a set of general security properties for mobile agents route protection and reduces the computational complexity of route protection to O(n) compared with the one based on nested encryptions.


The major aim of this study was to determine the antibacterial activity of plant essential oils against five food borne bacteria. The antibacterial activities of cinnamon, clove, oregano, rosemary and thyme oils were investigated against Campylobactersp., Listeriasp., Yersiniasp., Salmonellasp.and Pseudomonas sp.by agar well diffusion method, minimum inhibitory concentration (MBC) and minimum bactericidal concentration (MBC) method. Most of the essential oils showed a relatively high antibacterial activity against all the food borne bacteria. Of the essential oils studied, clove, cinnamon and thyme are the more inhibitory activity against all five food borne bacteria. The ranges of MIC of the essential oils were 50 – 60, 60 – 80 and 80 – 100 µl ml -1 , respectively, for clove, cinnamon and thyme. This work shows that essential oil is more effective against food borne pathogens and spoilage bacteria and could be used as natural antibacterial agents in food preservation.


Lipid oxidation is an important parameter for food conservation, since it alters its sensory properties in addition to generating the formation of free radicals. In this way, antioxidants are added to the processed product, and due to the greater concern for health, research of natural antioxidants has been highlighted. Bioactive compounds with antioxidant activity are generally unstable due to their chemical structure, so encapsulation techniques become attractive in the preservation of these substances. Therefore, the objective of this work was to carry out a literature review on lipid oxidation in foods, as well as encapsulation techniques to avoid these changes. To carry out the research, the databases Science direct, Scielo and PubMed were consulted using the following keywords: encapsulation; microencapsulation; antioxidants; bioactive compounds. As a result, it was observed that different techniques are applied in the encapsulation of antioxidants, highlighting physical techniques spray drying and chemical techniques such as complex coacervation and nanoemulsions. Research demonstrates the importance of the origin of the polymer and core, proportion and factors such as pH and temperature in order to achieve satisfactory yield and efficiency, in addition to the importance of regulating these factors in order to project the controlled release of the core in the food. Key-words: antioxidant, bioactive compounds, encapsulation


PDE-based image segmentation based on the active contour model attracts many researchers due to its high precision of edge detection and the continuity of boundaries. Its basic idea is to define an energy functional on a dynamic curve which achieves its minimum when the curve conforms to the boundary of the objects. Thus, the image segmentation problem is in essence an optimization problem. The most widely used optimization method is the gradient descent method in PDE-based image segmentation. However, the convergence of the gradient descent method is very poor. In this paper, a quasi-Newton method is extended to the generalized quasi-Newton method, and then the generalized Newton method and the generalized quasi-Newton method are used to solve a simple region-based model and compared with the gradient decent method. Experimental results show that the generalized quasi-Newton method has accurate segmentation results in the least possible number of iteration. Moreover it is able to segment noisy images correctly.


In recent months several high‐profile breaches of consumer privacy have raised public concern about data gathering on the Web. The issue of privacy has led to lawsuits by consumers and consumer advocacy groups and investigations by government regulations. As businesses wrestle with the question of where to draw the line when it comes to collecting and using customer information, they continue to invest in new technologies to gather and analyze customer data to improve their marketing effectiveness. This paper will address the issue of consumer privacy rights and make recommendations for various stakeholders to assure consumer privacy rights in the age of the Internet.


Abstract We define a motivic analogue of the Haar measure for groups of the form $G(k((t)))$ , where $k$ is an algebraically closed field of characteristic zero, and $G$ is a reductive algebraic group defined over $k$ . A classical Haar measure on such groups does not exist since they are not locally compact. We use the theory of motivic integration introduced by M. Kontsevich to define an additive function on a certain natural Boolean algebra of subsets of $G(k((t)))$ . This function takes values in the so-called dimensional completion of the Grothendieck ring of the category of varieties over the base field. It is invariant under translations by all elements of $G(k((t)))$ , and therefore we call it a motivic analogue of Haar measure. We give an explicit construction of the motivic Haar measure, and then prove that the result is independent of all the choices that are made in the process.


Cereal bars are a nutritional food of sweetened and acceptable flavor and are a source of vitamins, minerals, fibers, proteins and complex carbohydrates. The objective of this work was to study the effect of dietary fiber concentration and sugar in cereal bars made of oats with a high dietary fiber content. In the research, oat flakes, bran and flour from cultivar UPFA 22, selected on the basis of the dietary fiber and b-glucans content, were used. The ingredients were used in amounts defined in laboratory tests. The experiment was carried out using a central composite rotational design applicable to the response surface methodology (RSM), and the effects of the sugar syrup concentration (70, 75 and 80 °Brix) and dietary fiber content in the formulation (12, 16 and 20%) on the chemical composition, calorie value, water activity, microbiology and sensorial characteristics of the cereal bars were evaluated. The results were analyzed by multiple regression and the significant linear, quadratic and interaction terms were used in the second order mathematical model. The results showed that oats can be used as an ingredient when making cereals bars presenting an adequate texture, flavor and appearance. The oats used in the formulation makes cereal bars with high dietary fiber and b-glucan content. The bars present acceptable sensorial properties, similar to the industrialized bars, with higher acceptability when made with average concentration of sugar and high dietary fiber content. The cereal bars present low water activity and are within sanitary specifications and can be stored for 60 days.


IN EARLY 1982, TRADING BEGAN at three different exchanges in futures contracts based on stock indexes. Stock index futures were an immediate success, and quickly led to a proliferation of new futures and options markets tied to various indexes. One reason for this success was that index futures greatly extended the range of investment and risk management strategies available to investors by offering them, for the first time, the possibility of unbundling the market and nonmarket components of risk and return in their portfolios. Many portfolio management and other hedging applications in investment banking and security trading have been described elsewhere1 ranging from use by a passive fund manager to reduce risk over a long time horizon to use by an underwriter to hedge the market risk exposure in a stock offering for one or two days. In considering the potential applications of index futures, it is clear that in nearly every case a cross-hedge is involved. That is, the stock position that is being hedged is different from the underlying portfolio for the index contract.2 This means that return and risk for an index futures hedge will depend upon the behavior of the "basis," i.e., the difference between the futures price and the cash price. Hedging a position in stock will necessarily expose it to some measure of basis risk-risk that the change in the futures price over time will not track exactly the value of the cash position. Basis risk can arise from a number of different sources, and is a more significant problem for stock index contracts than for other financial futures, like Treasury bills and bonds.3 The most apparent cause of basis risk is the nonmarket component of return on the cash stock position. Since the index contract is tied to the behavior of an underlying stock market index, nonmarket risk cannot be hedged. This is the essential problem of a cross-hedge. However, basis risk can be present even when the hedge involves a position in the index portfolio itself and there is no nonmarket risk. For one thing, returns to the index portfolio include dividends, while the index, and the index future, only track the capital value of the portfolio. Any risk associated with dividends on the portfolio will become basis risk in a hedged position. Still, dividends are fairly low and also quite stable, so this may not be a terribly important shortcoming.


The marine economy has become an important part of the national economy in Tianjin.In order to meet the higher requirements by the comprehensive marine management,rational use of marine resources,marine pollution and other aspects of comprehensive management,it's necessary to fully understand the existing marine environment conditions.Using hydro-meteorological investigations in the Bohai Bay during four cruises in 2006 and 2007(Tianjin Coast) and four fixed currents continuous observation station investigation data in summer 2006,the temperature and salinity distribution of Tianjin coastal waters is analyzed.The historical data during Tianjin coastal zone and wetland resources investigation(current portion) has been verified.The analysis shows that the overall trend of summer circulation in the Bohai Bay has not changed greatly,but the residual current is very small;the flow rate has decreased and stays weakly compared to historical data;water temperature and salinity vertical changes lightly.


Lateral compositionally-graded thin films are powerful media for the observation of phase boundaries as well as for high-throughput materials exploration. We herein propose a method to prepare epitaxial lateral compositionally-graded films using a dual-beam pulsed laser deposition (PLD) method with two targets separated by a partition. Tuning the ambient pressure and the partition—substrate gap makes it possible to control of the gradient length of the deposits at the small sizes (≤ 10 mm) suitable for commercial oxide single crystal substrates. A simple Monte Carlo simulation qualitatively reproduced the characteristic features of the lateral thickness distribution. To demonstrate this method, we prepared (1−x)PbTiO3—xPbZrO3 and (1−x)LaMnO3—xLa0.6Sr0.4MnO3 films with lateral composition gradient widths of 10 and 1 mm, respectively, with the partitioned dual PLD.


Many canine patients have a requirement to return to the veterinary practice on a regular basis for treatment. Those that have associations of fear or anxiety with a practice, can find themselves i...


Raman spectroscopy is currently a part of the instrumentation suite of the ESA ExoMars mission for the remote detection of life signatures in the Martian surface and subsurface. Terrestrial analogues of Martian sites have been identified and the biogeological modifications incurred as a result of extremophilic activity have been studied. Analytical instrumentation protocols for the unequivocal detection of biomarkers in suitable geological matrices are critical for future unmanned explorations, including the forthcoming ESA ExoMars mission to search for life on Mars scheduled for 2018 and Raman spectroscopy is currently a part of the Pasteur instrumentation suite of this mission. Here, Raman spectroscopy using 785nm excitation was evaluated for determining various concentrations of beta-carotene in admixture with polyaromatic hydrocarbons and usnic acid have been investigated by Raman microspectrometry to determine the lowest levels detectable in simulation of their potential identification remotely in geobiological conditions in Martian scenarios. Information from this study will be important for the development of a miniaturized Raman instrument for targetting Martian sites where the biosignatures of relict or extant life could remain in the geological record. Keywords—Raman spectroscopy, Mars-analog, Beta-carotene, PAHs.


What we have said makes it clear that music possesses the power of producing an effect on the character of the soul. (Aristotle, The Politics , 1340a) It is a pervasive idea in Western culture that music possesses social and emotional content, or that its semiotic codes are linked to modes of subjective awareness, and in turn, social structures. Equally pervasive, however, is the view that music's social force and social implications are intractable to empirical analysis. At the level of the listening experience, for example, music seems imbued with affect while, at the level of analysis, it seems perpetually capable of eluding attempts to specify just what kind of meaning music holds and just how it will affect its hearers. The point of this chapter is to explore the 'gap', as John Rahn once put it (1972:255), 'between structure and feeling', and to derive from it an ethnographically oriented, pragmatic theory of musical meaning and affect, one located on an overtly sociological plane. Such a theory emphasizes music's semiotic force as the product of what can be called 'human-music interaction'. The interactionist critique of semiotics – overview This chapter considers musicological readings of works, socio-linguistic conceptions of meaning in use, and social science perspectives on material culture. Its aim is to draw these perspectives together and to propose a theory of musical affect in practice. The argument can be summarized as follows: implicit in much work devoted to the question of musical affect is an epistemological premise.


The elongation technology was reviewed and analyzed,and a novel design idea for the equal division of blade mold was proposed.Though a simple transformation of elongation technology,these modules such as blade slot,inside diameter and outside diameter etc.are machined,and openning is made ustilzing equal division,followed by machining the cutting face,the required equal divided modules with uniform angle can be obatined.The elongation technology can effectively eleminate the errors caused by machining single blade module,thus improving the machining efficiency and providing a new approach for the equal division mold of investment casting.


Objective
To explore the effect of recombinant protein growth differentiation factor-9 (GDF-9) on follicular development in mice.

Methods
Thirty eugamic KM mice were divided into three groups, which received human menopausal gonadotropin (hMG) 10 IU, hMG 10 IU with recombinant protein GDF-9 10 μg (combination group) and normal saline (0.5 mL) i.p. (control group), respectively; 48 h later, human chorionic gonadotropin (hCG) 10 IU was injected into each mouse, 16-20 h later 30 mice were killed, their ovary weight and the number of follicles were compared. Enzyme linked immunosorbent assay (ELISA) was used to examine the level of serum estrogen (E2), their oocytes were fertilized in vitro, and fertilization information was observed.

Results
The number of follicles (28.9±10.2, 36.5±13.0), ovary index [(32.26±6.33) mg/100 g, (38.80±8.90) mg/100 g] and the level of serum E2 [(45.64±14.19) ng/L, (52.02±16.08) ng/L] after ovulation induction in hMG group and combination group were higher than those of control group [11.4±5.4, (26.11± 7.16) mg/100 g, (25.03±13.62) ng/L], with statistical significances (P=0.001, P=0.034, P=0.029; P=0.000, P=0.028, P=0.014), especially, and they were significantly higher in combination group than in hMG group (P=0.025, P=0.031, P=0.043). There were no significant differences in fertilization rate among different groups (P>0.05).

Conclusion
Recombinant protein GDF-9 combined with gonadotropin (Gn) could effectively increase oocyte retrieval rate in mice, while had no influence on mouse oocytes fertilizability. Utilizing recombinant protein GDF-9 combined with Gn provide a new clinical idea for improving ovarian response to ovulation stimulation.

Key words:
Ovulation induction; Growth differentiation factor-9 (GDF-9); Gonadotropin (Gn); Ovarian response (OR)


Ron, the tyrosine kinase receptor for Macrophage Stimulating Protein (MSP) activates multiple intracellular signaling pathways promoting cell proliferation, motility, invasiveness and morphogenesis. Decoration of Receptor Tyrosine Kinases (RTKs) by ubiquitin is a signal for receptor internalization and routing to degradative compartments. Here we report the existence of a dual mechanism for Ron receptor downregulation. Ron is ubiquitylated in ligand‐independent manner by the U‐box E3 ligase CHIP (C‐terminal Hsc70 interacting protein), recruited via chaperone intermediates Hsp90 and Hsc70. CHIP controls receptor turnover, as demonstrated by gene silencing experiments. Following ligand‐induced activation, Ron recruits the negative regulator c‐Cbl, which mediates receptor polyubiquitylation and degradation mostly via proteasome, in contrast with lysosomal‐dependent degradation of multi‐ubiquitilyated receptors. The molecular mechanisms regulating Ron trafficking to degradative compartments was assessed by function‐impaired mutants or by gene silencing of chlatrin‐ or caveolin‐dependent endocytosis. While chlatrin is not involved in receptor degradation, Ron can directly interact with caveolin‐1 and interference with caveolae/raft‐dependent endocytosis affects Ron sorting to degradative compartments.


Beak deformities are abnormal growth of beakeither shortening or elongation of the beak or in abnormal shape and size. Different forms of beak deformities were observed among birds, but the exact causes of these abnormalities are unknown. Many reasons could be attributed for bird beak deformity which may be environmental contamination, nutritional deficiencies, injury, bacterial or viral infections, fungal or parasitic infections (Handel et al. 2010). Earlier, observations had been made and documented on birds with abnormal beak growth (Craves 1994). According to Handel et al. (2010), environmental contamination of organochlorine compound of selenium from Great Lake in California could be responsible for high rates of beak malformations. The beak deformity will affect the behaviour of birds for feeding (Benkman & Lindholm 1991; Temeles & Kress 2003), preening (Van Hemert et al. 2012), feather maintenance, cleaning of ectoparasites (Clayton et al. 2005). Birds with beak deformity change their habits and adapt to the malformations for their survival (Verea & Verea 2010).


Ozet Şiir ve ask arasinda dogal baglantilarin olmasi lirik siirin degerli ve onemli hale gelmesine neden olmustur. Modern cagda da, insanin hayati ve yasam tarzinin cok degismesi bu tur siirin belirli ozelliklerinin ortaya cikmasina neden olmuslardir. Bircok arastirmaciya gore Nima bu tur siirin temellerini atan sairdir. Bundan dolayi bu makalenin yazari farkli yonlerden bu tarz siirin ozelliklerini ve onun ilerlemesini arastirmak istemistir. Anahtar Sozcukler: Nima, siir, lirizm, ask. Abstract There are inherent and natural links between poetry and love which has been caused the value and importance lyrical poetry. In the modern era, the emergence of many changes in man's life and his approach, has led to that this kind of poetry have its particular properties. Since most people believe that Nima is founder of lyrical poetry, the author of this article, aim to classify properties of this portion of his poems and check from different directions, and as far as he can, show his influence on the progress and development of this type of poetry. Key Words: Nima, poetry, lyric, love.


Two cyclic (alkyl)(amino)carbene (cAAC) stabilized mononuclear neutral radicals of aluminum have been synthesized. They contain an ethyl [(cAAC)2AlClEt (1)] and as well a diethyl group [(cAAC)2AlEt2 (2)], and have been prepared from the reduction of EtAlCl2 and Et2AlCl, respectively, with KC8. Compounds 1 and 2 are monoradicals, which were confirmed by EPR measurements to have the spin located on the carbene carbon of one of the cAAC ligands.


Recently smart phones have been proliferating widely and quickly. Since the number of mobile apps that are being developed and deployed to domestic/international app stores is rising, more apps are being installed and deleted by users without any difficulty. The deployed apps are each attested through distinct verification framework of specific app stores. However, such verification frameworks are insufficient in checking security concerns. Unfortunately, the security verification framework is necessary since the incidents of leaking privacy and confidential information are being increased in lately. The aim of this paper is to provide the security verification framework that assures security and reliability of the e-government mobile apps. In order to verify proposed verification framework, a few apps were selected and inspected through proposed framework and these inspection results are included in this paper.


Based on the proposal and relevant discussion of the <||>blog real name system<||>, this paper, using stratified random sampling and typical sampling methods, firstly analyzes the Internet real name situation of web2.0 sites in China. Then through analyzing the investigation conclusions, the author points out that web2.0 sites in China, which asking their customers to using real name, mainly include the sites of business nature or tendency. At the same time, he points out that the sites concerning personal privacy and social expression usually don't call for real name. Finally, the author points out that <||>blog real name system<||> should not be mandatory.


Ethidium bromide has been reported to extract estrogen receptors from uterine nuclei whereas actinomycin D appears to block nuclear receptor "processing" in MCF-7 cells. We have examined the effect of these drugs on the nuclear estrogen receptor during the [3H]estradiol exchange assay. Uterine nuclear fractions were prepared from ovariectomized rats that had received a 5-pg subcutaneous injection of e&radio1 1 h prior to killing. Incubation of nuclear fractions with [3H]estradiol at 37°C resulted in a rapid labeling of nuclear estrogen receptor within 30 min which was followed by a loss of receptor sites that qualitatively resembled nuclear estrogen receptor processing. The addition of actinomycin D or ethidium bromide blocked this loss of nuclear estrogen receptor, resulting in a prolonged elevation of specific nuclear [3H]estradiol binding. Examination of the DNA by polyacrylamide-agarose gel electrophoresis showed extensive fragmentation that could be inhibited by actinomycin D in a dose-dependent manner. These findings suggest that a nuclease(s) present in crude nuclear fractions was responsible for the DNA fragmentation and loss of nuclear estrogen receptor complexes. Nuclear estrogen receptor release and DNA hydrolysis did not occur in highly purified nuclei. Nuclear estrogen receptor lost at 37°C could be recovered in the supernatant fraction as a family of soluble macromolecular complexes. Low salt sucrose gradients of this fraction showed specifically bound [3H]estradiol in an aggregate fraction that sedimented to the bottom of the gradient, and a free 8 S form. Both of these were converted to a 6 S form in gradients containing 0.4


Observations suggest that protoplanetary disks have moderate accretion rates onto the central young star, especially at early stages (e.g., HL Tau), indicating moderate disk turbulence. However, recent ALMA observations suggest that dust is highly settled, implying weak turbulence. Motivated by such tension, we carry out 3D stratified local simulations of self-gravitating disks, focusing on the settling of dust particles in actively accreting disks. We find that gravitationally unstable disks can have moderately high accretion rates while maintaining a relatively thin dust disk for two reasons. First, accretion stress from the self-gravitating spirals (self-gravity stress) can be stronger than the stress from turbulence (Reynolds stress) by a factor of 5–20. Second, the strong gravity from the gas to the dust decreases the dust scale height by another factor of ∼2. Furthermore, the turbulence is slightly anisotropic, producing a larger Reynolds stress than the vertical dust diffusion coefficient. Thus, gravitoturbulent disks have unusually high vertical Schmidt numbers (Sc z ) if we scale the total accretion stress with the vertical diffusion coefficient (e.g., Sc z ∼ 10–100). The reduction of the dust scale height by the gas gravity should also operate in gravitationally stable disks (Q > 1). Gravitational forces between particles become more relevant for the concentration of intermediate dust sizes, forming dense clouds of dust. After comparing with HL Tau observations, our results suggest that self-gravity and gravity among different disk components could be crucial for solving the conflict between the protoplanetary disk accretion and dust settling, at least at the early stages.


Corridors and waiting rooms are as important to the patient experience as clinical spaces. Yet in modernist hospitals they tend to be isolating, soul-destroying places to be. Since the 1970s, Toronto-based Montgomery Sisam Architects have been redressing the balance, enhancing patient wellbeing and restoring a connection to the great outdoors by focusing on the porch, the gallery and the courtyard.

Terry Montgomery, one of the firm's cofounders, here cites their inspirations, from traditional towns and centuries-old hospitals to modern urban theorists, and presents some of their recent buildings.


There is a moment in the film Brokeback Mountain (2005, dir. Ang Lee) when the cowboy Ennis seeks out the smell, the scent, the presence – in sorrow – of his lover Jack, who was beaten to death by homophobe rednecks earlier in the film. Ennis finds a worn denim work shirt, stained with Jack's blood on the cuff, hanging in the wardrobe at Jack's parent's home. The parents, waiting downstairs, silently acknowledge their son's illicit love and the grief of his lover. The love caught here in the fabric of a denim shirt is indescribable in its poignancy, its sense of loss, its use of a simple shirt as a device for human suffering of immeasurable scale.

Death and desire couple on cloth, creating a lexicon of erotic intimacy and masculine mourning. This paper explores this lexicon through three cloths: Jack's shirt, the shirt in which Irish Easter Rising patriot, James Connolly, was shot, and the homo-erotic symbolism of the non-shirt shit-impregnated blankets of Northern Irish Hunger Striker, Bobby Sands.


The intensification of deforestation and the consequent fragmentation of the natural landscape in urban and periurban watersheds affect the entire eco-hydrological system, increasing the need to understand how these changes can affect their sustainability. In this sense, the present study evaluated the potential implications of forest fragmentation for the management of the Tarumã-Açu basin, based on the characterization of the structural and functional patterns of the landscape. For this, we mapped and categorized the basin's forest fragments, based on the supervised classification (Bhattacharyya Method) of Landsat/OLI image, and, subsequently, we calculated the landscape metrics (area, density and size, edge, form, core, isolation and connectivity). The metrics showed a very fragmented landscape, especially in the region of the basin's low course, which concentrates the smallest, most dispersed, and vulnerable fragments even in conservation units. The headwater region, on the other hand, has the largest patches, with a large amount of central area and high structural and functional connectivity, which are fundamental for the sustainability of the basin and, therefore, deserve attention and prioritization by managers. The results offer important subsidies and unpublished data that can contribute to elaboration of the basin's management plan and for the definition of conservation and restoration strategies of the forest remnants, indicating priority areas for the implementation of these actions.


Interactivity is a concept familiar from the computer sciences since the 1960s, and one which has, since the late 1980s, gained greater currency, integrating itself through the computer into the larger culture. Art-making is one of those areas where we hear about such integration in the form of interactive video. A brief look at precursors, instances of artists earlier on using performances and events and objects to involve or engage viewers, often transforming them into performers, draws the current situation and the dynamics and practices of interactivity in the world of contemporary art into relief with the work of six artists to be discussed in particular. With the futurists and the dadaists early in the century, and in the late fifties and sixties with happenings, Fluxus, actionism, and proto-pop, artists' performances and events were engaged in breaking down the barriers between art and life, wearing away the walls of aestheticism built up with modernist movements such as cubism, purism, expressionism, later abstract expressionism. " Epater le bourgeois " was the early motto capturing the essence of a futurist event on the streets or in a theater in Milan or Turin or a dada evening provoking the audience in a Zurich cafe. The audience was pushed, even taunted into responding to a performance or a series of tableaux, a poetry reading, a manifesto declaimed, aimed at shocking or insulting; success for the artists was measured by the reaction of the audience - shouts, egg throwing, riots, the more the better. The provocation became an expectation for the audience, then a cliche, as the strategies wore out (see Goldberg) .


Wireless Sensor Networks (WSN) consists of large amount of nodes spread either arbitrarily or non-arbitrarily in the region of interest for sensing an event. The main constraint in WSN existence is the consumption of energy by tiny sensor node during operation. For increasing the lifetime of WSN, various clustering techniques have been evolved in the last decade. Energy Consumption by the node primarily depends upon the distance between nodes to Cluster Head (CH), CH to Base Station (BS) and the Length (L) of the packet being transmitted. It has been analyzed that combinations of two different techniques i.e. EECA-F and H-PEGASIS can solve variety of issues. In this paper, two techniques are combined together to form Hybrid Energy-Efficient Clustering Technique (HEECA). Results revealed that in HEECA mechanism, nodes consume 1.75J energy even after 80 rounds whereas in EECA-F the toll reaches 3J. On analyzing, it is found that clustering through HEECA protocol can save 41.7 percent energy in nodes thus making them live longer and eligible to be used in robust applications where replacing battery of a node is a tedious task.


Based on the coordinate transformation theory,this paper utilizes the square Split-Ring Resonators as the unit cell main body and designs a two-dimensional invisible cloak.The CST Microwave Studio is used to optimize the different layers' structure of the invisible cloak with the frequency of 8.5 GHz.The designed two-dimensional invisible cloak is fabricated and measured by the plane wave-guide system.The measured result verifies that the cloak made by the designed metamaterial has a better invisible capability.This research gives a realizable way which makes the things inside the cloak unable to be detected.


N-Chlorobenzotriazole (BT–Cl) and N-tert-butyl-α-phenylnitrone (PBN) react thermally or photochemically at room temperature with the formation of two isomeric benzotriazolyl spin adducts and the chloro spin adduct, as monitored by EPR spectroscopy. The benzotriazolyl spin adducts are subsequently converted into benzotriazolyl phenyl ketone O-benzoyloxime while the latter is converted into the N-benzoyl-N-tert-butyl aminoxyl radical. Normal solvents do not substantially influence the spin adduct distribution, but the reaction becomes faster in the order of benzene < dichloromethane < acetonitrile. The reaction is autocatalytic in benzotriazole, provided a suitable H atom donor is present, e.g. the solvent or added toluene. In 1,1,1,3,3,3-hexafluoropropan-2-ol, a solvent which strongly suppresses nucleophilic processes, only the benzotriazolyl spin adduct is detectable. The macroscale reaction between BT–Cl and PBN confirms the fate of the radicals detected by EPR spectroscopy. The structures of (Z)- and (E)-benzotriazolyl phenyl ketone O-benzoyloxime were determined by X-ray analysis.


AT THE UNITED NATIONS International School in New York City, circumstances dictated that the Humanities Department develop a new way of introducing history to its multinational student community. A few statistics will give some sense of the difficulties involved. This year the school has over 1,400 students ranging in age from five to eighteen; they come from 107 different countries. Their parents, primarily members of the Secretariat staff, demand an academic program that will make it possible for their children to return to their national system, or to move on to a third system, with a minimum of dislocation and confusion. From the point of view of our department this means not only giving the students a positive picture of their own national heritage, but also some understanding of the personalities and forces that have shaped others' histories. Initially, we presumed that the varied backgrounds of the members of our department-we come from eight different countries including India, Austria, and Sierra Leone-would make formulation of


Accuracy of automatic syntactic analysis of natural languages with relatively free word order (such as Czech) can be hardly improved without building large and precise lexicons of syntactic behavior of individual words (e.g. lexicons of verb valency frames). The current treebanks available do not cover enough words. Larger corpora lack the syntactic annotation and many sentences contained in them are too complex to extract the information easily or even automatically. The system AX (automatic extraction) was developed to perform selection of morphologically analyzed sentences by means of custom hand-written rules. The rules can be easily formulated to perform linguistic-motivated filtration. The system AX allows to perform partial syntactic analysis in order to check the occurrence of more complex linguistic phenomena. 1 Motivation At the current stage of the development, the accuracy of automatic syntactic analyzers of natural languages (in particular Czech) is limited due to the lack of large and precise lexicons of syntactic behavior of individual words (verb valency frames are the most important example). Building such lexicons by hand is rather a time-consuming task and any kind of automatic preprocessing would help. The available data sources include corpora annotated on different levels of linguistic description. Syntactic information can be easily extracted from corpora annotated on the syntactic level (such as the Prague Dependency Treebank, PDT1, Böhmová et al. (2001)) and some attempts to extract for example verb subcategorization frames from treebanks were already performed2. However the number of occurrences of individual lexical items in http://ufal.mff.cuni.cz/pdt/ Such as (Sarkar and Zeman, 2000). Proceedings of the Eighth ESSLLI Student Session Balder ten Cate (editor) Chapter 1, Copyright c © 2003, Ondřej Bojar 1 Building Sub-corpora Suitable for Extraction of Lexico-Syntactic Information such corpora is usually not sufficient. Bojar (2002) shows that only a few hundreds of verbs have enough occurrences in PDT and that more than 60% of 26,000 verbs found in the Czech National Corpus (CNC3) are not covered in PDT at all. Therefore, it is necessary to extract the lexico-syntactic information from larger corpora (such as the CNC) or any texts available. However, not all sentences containing a given lexeme can serve as a good example to extract the syntactic information (for instance, if two verbs are present in one clause, their complements and adjuncts can be arbitrarily intermixed). And moreover, as the syntactic annotation in these corpora is missing, the sentences can often be too complex to be analyzed by any of the available parsers at a reasonable level of accuracy. I developed the system AX to simplify the task of selecting feasible examples of sentences for extracting a specific lexico-syntactic information (not just the verb valency frames). The sentences can be easily selected on linguistically based criteria. Partial syntactic analysis of sentences is possible, in order to be able to answer more complex linguistic questions about the sentence. In section 2 I describe the overall architecture of the system AX. Section 3 gives a brief description of the basic data structure, variant feature structure. Sections 4 and 5 describe the core of the scripting language AX: filters to reject sentences and rules to perform (partial) syntactic analysis. In the last section, I illustrate the use of the system to select sentences suitable for extracting valency frames of Czech verbs and document the improvement of accuracy of Czech parsers when applied only to the selected sentences. 2 The Architecture of AX The system AX combines the idea of regular expressions and replacements (see (Karttunen et al., 1996; Aı̈t-Mokhtar and Chanod, 1997) and others) with the idea of feature structures (see below) known from unification-based parsers. This combination leads to a formalism that is both, strong to describe complex linguistic properties of sentences of natural language and efficient in the process of parsing. The user prepares a script of filters and rules to select sentences suitable for a specific purpose. The system AX loads the script and then expects sentences augmented with their morphological annotation (in format of the PDT4) on the standard input. The input sentences may or may be not morphologically disambiguated. For every input sentence, the system runs the script and checks, if the sentence passed all the filters or has been rejected. For sentences that pass (referred to with the term "selected sentences"), the output of the final phase (see below) is printed out. This output is for some http://ucnk.ff.cuni.cz/ See http://shadow.ms.mff.cuni.cz/pdt/Corpora/PDT 1.0/Doc/morph.html 2


The relationship between public health capacity to fight infectious diseases and foreign direct investment is circular.  Foreign companies may be wary of investing in a location that lacks the capacity to mitigate the consequences of disease or exposes workers to dangerous pathogens.   Yet, many nations lack the resources to build sufficient capacity to prevent, detect and respond to disease without sufficient investments and improve economic status.  Here, we explore how to incentivize and offer some assurances to potential investors contemplating investment in a developing country considered a hotspot for future infectious disease outbreaks, as well as means to encourage development of national capacities to prevent, detect and respond to biological threats.   We suggest that the Multilateral Investment Guarantee Agency (MIGA), part of the World Bank Group, could guarantee private investment against infectious disease events, based on a formula that rewards countries for making improvements in public health capacity.


Our view on the deep universe has been so far biased towards optically bright galaxies. Now, the measurement of the Cosmic Infrared Background in FIRAS and DIRBE residuals, and the observations of FIR/submm sources by the ISOPHOT and SCUBA instruments begin unveiling the ``optically dark side'' of galaxy formation. Though the origin of dust heating is still unsolved, it appears very likely that a large fraction of the FIR/submm emission is due to heavily-extinguished star formation. Consequently, the level of the CIRB implies that about 2/3 of galaxy/star formation in the universe is hidden by dust shrouds. In this review, we introduce a new modeling of galaxy formation and evolution that provides us with specific predictions in FIR/submm wavebands. These predictions are compared with the current status of the observations. Finally, the capabilities of current and forthcoming instruments for all-sky and deep surveys of FIR/submm sources are briefly described.


Today, people depend on the digital media in order to get information that will make them stay healthy. The digital media have become indispensable in the field of advertising and health because of its numerous benefits. This study investigated the effectiveness of digital media platforms in advertising of health supplements in Owerri metropolis. The elaboration likelihood model was adopted as the theoretical foundation. The survey research approach was used. The study had a population of 555,500 from which 384 was derived as the sample size using Wimmer and Dominick online sample size calculator. The multistage sampling technique was used. Questionnaire served as the instrument for data collection and the simple percentage was used for the data analysis. Findings revealed that 69.3% of the respondents confirmed that advertisements of supplements on digital media platforms promote sales of health supplement products among consumers. It was also revealed that at an average of 66.3% respondents confirmed that digital media have been effective in the advertisement of health supplements in Owerri metropolis. Further findings revealed that many of the respondents 111 (31.2%), were of the view that societal ideologies stand tall as challenges that hinder the acceptance and patronage of these supplements in Owerri metropolis despite the digital media advertisement. It was recommended that advertisers should not stop being creative in their advertising outings on the digital media so as to keep influencing consumers positively and to maintain its effectiveness in the promotion of health supplement products.


The production of ethanol from lignocellulosic biomass has gained increased interest in recent years, notably in the context of valorising agricultural by-products and providing fuels from renewable sources In order to increase their competitiveness, the energy demand of such processes needs to be minimised. This issue procures two benefits : (1) reduce utility consumption and (2) increase cogeneration possibility. In the present article we investigate this problem for a study process: ethanol production from sugarcane bagasse by enzymatic hydrolysis and glucose fermentation. We therefore apply a rigorous optimisation methodology in which we control certain design parameters in order to maximize the net production of utility. As a result, we obtain a design for our process which (1) eliminates the need for an external hot utility, (2) minimizes the need for the cold utility and (3) maximises the cogeneration possibility.As a conclusion, the proposed methodology provides a strong tool for minimising the utility consumption for a 2G ethanol plant. Considering its key components, it can further be applied in the context of a multi-objective problem.


Selecting a single piece of typical rectangular open planar magnet,with its axial magnetization, to build a finite element model. Based on ANSYS software, the article used NdFeB45 material properties, giving 100×100×10mm to fit the relationship of three-dimensional size. In the air zone as 10 times as model size, it adopted a static simulation analysis of the effect on relationship between axial magnetic distance and magnetic field strength. The magnetic field contours as simulation results, after the Origin software fitting process, obtained an equation is: ; Comparing with the formula: , which reflected the basic characteristics of permanent magnetic field, and with the numerical results by Jing-tian LI using equivalent magnetic charge method, they all appeared: the magnetic field strength exponentially decrease along with the magnetic distance increases, the magnetic field non-uniformity coefficient is of 4.628% deviation, the fitting correlation coefficient R is 0.99924; As a result of the numerical verification results, it also visually response to the magnetic field parameters of open permanent magnet.


Spatial ecology and the spatial sciences in general are increasingly applied to support evidence-based policy and environmental management decisions in an era of global change. The effects of global change agents – climate change, land-use change, novel species, and altered biogeochemical cycles and disturbance regimes – play out over multiple spatial and temporal scales. International and multilateral agencies are calling for spatially explicit information in support of policy and management supporting biodiversity, ecosystem services and sustainable environmental management. Conservation and environmental planning can no longer be restricted to a static landscape but must explicitly account for temporal dynamics. This is the Fourth Special Issue on Spatial Ecology in the International Journal of Geographical Information Science, following from previous issues in 2011, 2012 and 2014 (Skidmore et al. 2011, Laffan et al. 2012, 2014). The papers in this special issue contribute to the points listed above, with a particular focus on dynamics in space and time. A cross-cutting theme in this issue is human–wildlife interactions and conflicts in space and time (Loraamm and Downs this issue, Saito et al. 2016, Zengeya and Murwira 2016), a topic also covered in previous special issues (David Walter et al. 2011, van Langevelde and Grashof-Bokdam 2011). Further linkages between humans and ecological processes are assessed by Fagúndez and Izco (2016), who explore the use of toponyms as a means of identifying historical vegetation types. Cost-path analysis continues to be widely used in spatial ecology to represent landscape connectivity (Adriaensen et al. 2003, Lyon et al. 2010, Greenberg et al. 2011, Etherington 2012, Hanke et al. 2014, Hohl et al. 2014, Bishop-Taylor et al. 2015). In this respect, papers in the special issue summarize important applications in the design of wildlife corridors (Loraamm and Downs this issue) and methodological improvements in the characterization of uncertainty (Etherington and Perry 2016).


Introduction: Colorectal cancer (CRC) is one of the most common cancers globally. Chemotherapeutic drugs are frequently used in postoperative treatment. The platinum compound oxaliplatin (OXA) is a ...


The main feature of the modern tourism market is an increasingly emphasized competitive pressure. Due to more extensive travel experience and improvement of quality in the process of supplying information by the travel agencies, as well as due to a wider range of travel destinations, tourists are now more demanding and sophisticated in their preferences and expectations. Innovativeness in business is the basic prerequisite of successful operation and survival of companies in the tourism market. Tourism is a complex system and a great number of different companies (travel agencies, tour operators, transporters, hotels, different companies at travel destinations, etc.) take part in designing a tourist product. Tour operators have a significant role in the tourism value chain as the most relevant type of intermediaries in sales of services. Within their business activity, the tour operators combine different services to form package tours and organize travels for tourists. In modern tourism there is a pronounced trend of independent searches and bookings, which directly reflects on the demand for products and services offered by tour operators. Due to changes in the tourism market, there is an increasing need to adapt the business activities of tour operators. Package tours are the core product of tour operators, and their business results largely depend on the success in the designing and sales of such products. This paper analyzes different elements of tour operator package tours, aiming to determine the level of significance of different benefits which the package tours offer to tourists. The research has been conducted based on the application of the AHP research methodology. The basic idea behind the paper is to use the AHP methodology to determine the most significant benefits in order to conduct an in-depth analysis of significance of different elements of package tours designed by the tour operators for tourists for the purpose of defining basic guidelines for designing the offer and achieving competitive advantage in the market.


A mathematical model, proposed recently to describe longitudinal waves in the nonlinearly elastic thin-walled cylindrical shell, is used to derive an equation for the longitudinal strain component in case of variable geometrical and physical properties of the shell. To solve the Cauchy problem for this equation the finite difference scheme is proposed, that satisfies the conservation laws of "pseudo-mass" and "pseudo-energy" for a solitary wave solution. A numerical simulation, based on this scheme, is performed to study evolution of the strain soliton in a cylindrical shell with variations of both cross section of the shell and the physical properties of the material.


At the end of January 1821, the liberating army under the command of General José de San Martín was in Huaura and the royalist army under the orders of Viceroy Joaquín de la Pezuela was stationed in Aznapuquio, an area located in the coastal sector, south of the Chillon river. Approaches for combat begin. Then, the royalist leaders deposed Pezuela from command and placed General José de La Serna as Viceroy. There had been a viceroyalty "coup d'état" that marked the course of the war of independence.


The occurrence of malnutrition in children is not only due to the nutritional content of the food served, but also
caused by the occurrence of health problems, so that the ability to endure and dream of eating will be reduced and susceptible to disease so that the child can experience malnutrition. The purpose of this study was to compare the nutritional status of children under five before and after being given a modified supplementary diet. The research method uses a quasi-experimental research design with pre-test - post-test design with treatment. The sample is a number of toddlers in Puton Village, Diwek District, Jombang Regency. The study was conducted for 4 weeks by providing additional modified food to toddlers with nutritional problems. The sample by means of total sampling. The dependent variable in this study is the ability to provide additional modified food, the independent variable is the nutritional status of children under five. Data analysis using t-test. The results showed that most (70%) nutritional status of children under five improved after being given additional modified food. This study is expected to provide knowledge about other modified food additives and the intervention time of 4 weeks is not optimal enough to improve the nutritional status of toddlers so that it takes a longer time for this intervention to get maximum results.


Geriatric evaluation of older patients with progressive chronic kidney disease is recommended in guidelines to enhance decision-making for kidney replacement choices. Although frailty, physical and cognitive impairments, and depression are prevalent, routine identification of geriatric impairments is lacking. Therefore, we aimed to study feasibility and determinants of successful implementation of a novel approach: nephrology-tailored geriatric assessment.

 In a mixed-methods implementation study, we investigated the feasibility of implementation of a consensus-based geriatric assessment [1] in Dutch nephrology centers. Feasibility was assessed through hospital participation and patient inclusion (among patients aged 70+ years with eGFR≤20mL/min/1.73 m2). We also evaluated determinants of successful implementation with a post-implementation survey among healthcare professionals covering (i) perceived enablers and barriers of implementation, (ii) perceived integration in work routines (Normalization MeAsure Development tool), and (iii) perceived relevance of the instruments. In addition, patients were asked if the geriatric assessment provided them with new insights for their future treatment decision for kidney failure.

 Feasibility was substantiated in implementation of geriatric assessment in 10 hospitals among 191 patients, i.e. 100% and 96% of our aimed goals. According to participating healthcare professionals (n = 71), determinants that facilitated implementation were: collaboration with the geriatric department, multidisciplinary meetings and reports, and execution of assessments by nurses. Most frequently mentioned barriers to implementation were: patient illiteracy or language barrier, lack of time, and burden for patients. Professionals considered geriatric assessment sufficiently integrated into work routines (mean 6.7 of 10, SD 2.0), but also subject to improvement (Figure 1). Implementation of geriatric assessment was considered sufficiently relevant for routine care (mean score 7.8 of 10, SD 1.2). Half of the patients (n = 42/82) stated that the geriatric assessment provided them with new insights, whereas 27% (n = 22) responded not to have gained new insights from the tests.

 Multicenter implementation of nephrology-tailored geriatric assessment seems feasible and relevant. For future implementation we recommend involving the geriatric department, using multidisciplinary teams and -meetings, acknowledging the pivotal role of nurse practitioners, and using a flexible approach matching local resources.


Contents Acknowledgments I. 1. Expansion and Crisis 2. Bobby 3. The Ox 4. Big Mac and the Firewagon 5. The Second-Place Curse II. 6. The Race and the Free Throw Contest 7. Here We Go Again 8. Kiss It Goodbye 9. Speed versus Power 10. The Game Neither Team Could Afford to Lose 11. Century Mark 12. A Knife in Wisconsin 13. The Clincher III. 14. A Record Night in Chicago 15. Kansas City Coronation Epilogue Appendix: Stats and Records Notes Index


ABSTRACT The gastrointestinal tract of complex metazoans is highly compartmentalized. It is lined by a series of specialized epithelia that are regenerated by specific populations of stem cells. To maintain tissue homeostasis, the proliferative activity of stem and/or progenitor cells has to be carefully controlled and coordinated with regionally distinct programs of differentiation. Metaplasias and dysplasias, precancerous lesions that commonly occur in the human gastrointestinal tract, are often associated with the aberrant proliferation and differentiation of stem and/or progenitor cells. The increasingly sophisticated characterization of stem cells in the gastrointestinal tract of mammals and of the fruit fly Drosophila has provided important new insights into these processes and into the mechanisms that drive epithelial dysfunction. In this Review, we discuss recent advances in our understanding of the establishment, maintenance and regulation of diverse intestinal stem cell lineages in the gastrointestinal tract of Drosophila and mice. We also discuss the field's current understanding of the pathogenesis of epithelial dysfunctions. Drosophila Collection: This Review highlights recent findings on intestinal stem cell (ISC) diversity in the GI tract of Drosophila, focusing on the role of ISCs in healthy and diseased conditions, and drawing parallels to vertebrate GI stem cells.


Sleeping bags and sleeping pads present inevitable equipment of all sportsman dedicated to mountaineering. Major part of thermal insulation of a person sleeping in a sleeping bag ensures the proper bag, but more than 40% of heat escapes through the sleeping pad (mattress) down to the ground or floor. However, despite the importance of sleeping pads, related research reports are almost missing. In the study, heat transfer mechanisms in hollow sleeping pads filled with the pressure air (to increase their thickness) and modern sleeping pads additionally filled with porous polyurethane foam is theoretically and experimentally analysed. From the theoretical analysis follows, that sleeping pads filled with porous polyurethane structures exhibit approximately 2 times higher thermal resistance then empty inflated pads, due to the reduction of free convection in the internal space of the pads. These theoretical findings were confirmed by the experimental results presented in the paper.


The present invention provides an apparatus and method of automatically braking a vehicle in a stop state by using a signal of a vehicle-speed sensor in a vehicle, and can be used as an alternative to a parking brake. A stop signal conversion means (20), an accelerator pedal sensing means (40), a stopping/running judgement means (50), a switch means (60) and a electromagnetically operated switching valve (70) are comprised. One of a high-level signal and a low-level signal from the vehicle-speed sensor (10) in the stop state of the vehicle by pressing the brake pedal is detected as it is, and the other one of a high-level signal and a low-level signal from the vehicle-speed sensor (10) is converted by a stop signal conversion means (20) and detecting the converted one. A brake line (L) is closed and the vehicle is braked by detecting the stop state using a single signal from the vehicle-speed sensor (10) although the pressing of the brake pedal may be released.


technical writing basics a guide to style and form is available in our book collection an online access to it is set as public so you can download it instantly. Our books collection spans in multiple locations, allowing you to get the most less latency time to download any of our books like this one. Merely said, the technical writing basics a guide to style and form is universally compatible with any devices to read.


In the past decade, as more and more passengers choose to fly on trips, China's airport infrastructure construction has achieved world-renowned achievements. Despite the growing opportunities and demands for using brand research to assist airport industry services in improving, few studies have investigated the impact of service quality in terminal facilities on brand due to the diversity of service. This study uses structural equation models based on empirical research to explore the impact of facility service quality, including processing facility and non-processing facility, on airport brand experience and passenger satisfaction. This study also aims to assess the mediating effect of brand engagement on the relationship between facility service quality, brand experience, and passenger satisfaction. At the same time, this study also uses importance–performance map analysis (IPMA) to find specific items influencing brand engagement. The sampling method used a random sampling approach, with a total of 186 questionnaires distributed at Shanghai Pudong International Airport for data analysis. The results show that airport facility service quality is significant for brand engagement and experience, as well as for satisfaction, especially for processing facilities. In addition, the IPMA results show that facility services involved in the check-in process is of high importance, which requires more attention from managers. Overall, the findings of this study extend the understanding of service quality, brand engagement, brand experience, and passenger satisfaction in the context of an international airport, and they offer implications for Shanghai Pudong International Airport regarding the improvement of its facilities and brand.


The Tibetan sacred mountains (TSMs) cover a large area and may represent a landscape‐scale conservation opportunity. We compared the conservation value of forests in these mountains with the conservation value of government‐established nature reserves and unmanaged open‐access areas in Danba County, southwestern China. We used Landsat satellite images to map forest cover and to estimate forest loss in 1974–1989, 1989–1999, and 1999–2013. The TSMs (n = 41) and nature reserves (n = 4) accounted for 21.6% and 29.7% of the county's land area, respectively. Remaining land was open‐access areas (i.e., areas without any restrictions on resource use) (56.2%) and farmlands (2.2%). Within the elevation range suitable for forests, forest cover did not differ significantly between nature reserves (58.8%) and open‐access areas (58.4%), but was significantly higher in TSMs (65.5%) after controlling for environmental factors such as aspect, slope, and elevation. The TSMs of great cultural importance had higher forest cover, but patrols by monastery staff were not necessarily associated with increased forest cover. The annual deforestation rate in nonsacred areas almost tripled in 1989–1999 (111.4 ha/year) relative to 1974–1989 (40.4 ha/year), whereas the rate in TSMs decreased in the later period (19.7 ha/year vs. 17.2 ha/year). The reduced forest loss in TSMs in 1989–1999 was possibly due to the renaissance of TSM worship and strengthened management by the local Buddhist community since late 1980s. The annual deforestation rate in Danba decreased dramatically to 4.4 ha/year in 1999–2013, which coincided with the implementation of a national ban on logging in 1998. As the only form of protected area across the Tibetan region during much of its history, TSMs have positively contributed to conserving forest at a landscape scale. Conservation of TSM forests largely relied on the strength of local religious institutions. Integrating community‐based conservation of TSMs within the government conservation network would benefit the conservation of the Tibetan region.


Abstract Plumes of dense shelf water cascade down continental slopes in many parts of the world's oceans and provide a mechanism for shelf–ocean exchange. In this paper a nonlinear process-orientated theory is developed and used to examine the dynamics of cascading. The theory is formulated in terms of a "1½-layer" model and incorporates bottom topography, earth rotation, internal and bottom friction, and entrainment as well as externally imposed pressure gradients. The theory occupies a niche between the stream tube class of model (which considers only bulk properties of a plume) and the full three-dimensional primitive equation approach. The model provides useful insights into the complex interplay between the controlling forces, and it allows one to recover the shape and trajectory of dense plumes as well as the three-dimensional flow field inside the bottom layer. Asymptotic limits are investigated and lead to several basic results. A typical thickness of a fully developed plume is found to be twice t...


As the site of folding for proteins of the secretory pathway, the endoplasmic reticulum (ER) must be equipped with an efficient quality control machinery. Through ER associated degradation (ERAD) misfolded lumenal and membrane-bound proteins are tagged with poly-ubiquitin chains and degraded in a proteasome-dependent manner. ERAD is a multi-step process which is initiated by the identification of the misfolded protein. While lumenal substrates degraded by the ERAD-L pathway appear to be recognized by a number of factors, it is unknown how misfolded membrane proteins are identified by the ERAD-M pathway. As a rate-limiting factor for ERAD, and a specificity factor as a ubiquitin ligase, we tested whether Hrd1p plays a role in the identification of misfolded proteins. By mutating a number of conserved and hydrophobic residues within the Hrd1p transmembrane domain, we illustrated that Hrd1p can distinguish between misfolded lumenal and membrane proteins, and that specific residues were important for the degradation of specific membrane proteins. Thus, in addition to Hrd1p's role as a ubiquitin ligase, it appears that this protein plays a role in the recognition of misfolded membrane proteins as well. Our studies also demonstrated that substrate binding does not appear to be sufficient to initiate ubiquitination, and that some type of signal is required following binding in order to activate the RING domain of Hrd1p. Following substrate ubiquitination, the protein must be removed from the ER in a process known as retrotranslocation, as the proteasome is located in the cytoplasm. To study retrotranslocation, we established an in vitro retrotranslocation assay, which we demonstrated was capable of retrotranslocating a natural ERAD-M substrate, Hmg2p. Retrotranslocated Hmg2p was soluble and full-length, and the process was dependent on Cdc48. With this assay, we were able to test the current model of retrotranslocation, in order to determine the core set of proteins which are essential for this process. This uncovered a role for the factors Ubx2p and Rad23p/Dsk2p in retrotranslocation, while demonstrating that the putative retrotranslocons Sec61p, Der1p/Dfm1p, and Hrd1p are dispensible for Hmg2p retrotranslocation. These studies have greatly increased our understanding of HRD-dependent degradation


Hand washing is recognized as the most important preventive measure for the control of
hospital-acquired infections. The purpose of this study was to analyze the practice of hand washing by
health professionals, through playful-educative actions on the theme, accomplished during a
commemorative event in May 2003, at the Fernandes Figueira Institute, in Rio de Janeiro. A sink was
specially set up for the participants to accomplish the basic washing of their hands. Fifty professionals, in
a volunteer basis, have been observed by means of a structured observation method. The results showed
a poor technical performance, including the inobservance of the withdrawal of adornments (84%) and
application of the liquid soap without previous wetting of the hands (56%). Although most (80%) participants
have used more time than recommended (10 to 15 seconds), 54% didn't accomplish a complete washing.
We concluded that, in spite of the frequent educational campaigns and offering of appropriate products,
the professionals don't perform the technique satisfactorily.


Oxide layers on the cathode produced marked irregularities in the Paschen curves for air and hydrogen, especially in the neighbourhood of the minimum Vm. Vm in hydrogen was measured at different stages during the removal of oxide layers from the cathode, and also during the deposition of one metal on another as base. Removal of the oxide layer produced smooth Paschen curves, while a thin film of one metal on a different metal as base gave values of Vm which were not characteristic of either metal in bulk. The deposition of thin metallic films had considerable effect on cathode emission owing to the alteration of the work function


During recent years, the scientific activities related to noise mitigation in the environment of airports have been focused strongly on the development of noise abatement flight procedures. Such procedures – which are part of the "Balanced Approach" to aircraft noise management that is recommended by the International Civil Aviation Organization ICAO – cannot be designed effectively without the use of aircraft noise calculation programs. This paper gives an overview on the potentials of noise optimized operational procedures as well as their limits due to flight-mechanical constraints. Moreover, it will discuss the specific demands on the noise calculation models used to develop them. Special attention is paid to the definition of noise optimized approach procedures and the corresponding need to model airframe noise.


The bivalve species Cerastoderma glaucum (Poiret, 1789) was studied in this study. This species is allochthonous and belongs to the Mediterranean zoogeographic complex and was introduced in the Holocene. The C. glaucum is the dominant species among the bivalves in the Sea of Azov and has a wide range of distribution. The species is distributed in the coastal zone within 100-300 m from the shore, and it is also found in desalinated water bodies such as estuaries. The C. glaucum is fairly resistant to hypoxia. It is euryhaline with respect to salinity and eurybiontic with respect to soil. The species can settle on sandy, muddy or sandy-silty substrate. The aim of the study was to investigate the morphology of shells of this species in order to find out the reasons of morphological features change of Cerastoderma glaucum in different biotopes of the Sea of Azov. The study was conducted in early June 2021 on the northwestern coast of the Azov Sea. A total of 20 stations were investigated. Cerastoderma glaucum was found at all stations. The morphological variability of the bivalve Cerastoderma glaucum was investigated using the method of discriminant analysis. A notable morphological feature was the external alteration of the mollusc shell. A displacement of the apex to the anterior edge of the shell, lengthening of the posterior edge, and deformation of the shell shape, indicating the ecological characteristics of the study area and its inhabitants. Also, there is a difference in the ratio of shell height to shell length, indicating an increased level of siltation in the ground. Shell thickness varies in all survey areas, indicating different levels of salinity. The overall abundance of molluscs from the different biotopes indicates the factors determining the shape of cockle shells. In turn, morphological parameters indicate the general condition of the Sea of Azov. So, it can be assumed that siltation of the substrate on which benthic communities are located has increased as a consequence of massive deposition of phytoorganic residues. In addition, the hydrolytic regime has changed as a result of anthropogenic factors. As a consequence, salinity, oxygen levels are changing, etc.


Production of Molybdenum-99 from linear accelerators uel management of boiling water reactors TAPS #1 and 2 at Tarapur is Fvery challenging. These units have been successfully operated for the past 50 years with an intense collaboration between NPCIL and BARC. It is worth mentioning that BARC is the sole agency responsible for the optimization of core loading patterns and fuel management of these units.


JTTA KIRCHGEORG communication devices and the way we use them. It explores the mystification of [ultimedia CD-ROM modem technology and our resulting frustration with it and examines the underlying structures of control and power. 997 When I first came to the United States two years ago, I noticed that a considerable part of our communication was accomplished through machine interfaces. While this situation is not specific to the United States, it was the exposure to working in a second language in everyday life that brought it to the front of my consciousness. Routines I had never really thought about suddenly became difficult, sometimes unmanageable, tasks. The flaws in automation became evident and inspired me to further scrutiny and the creation of this hybrid CD-ROM. The Information Age is a statement on our avid commitment to rapidly developing technology and our acceptance of the resulting alterations in communication mechanisms, information access, and changed social structures. Under the guise of an educational presentation, The Information Age embodies a progressive technological disaster based on both my real experiences with modern technologies and my worst nightmares r about them. Structured into chapters about major achievements in electronic communications-the telegraph, the telephone, the radio, ' . B the television, the computer, and the Internet-it covers all crucial eras of the advancing Information Age. On the surface, the navigation and organization mimic other educational CD-ROMs, but there is a second, hidden level of functionality that becomes apparent only after a certain amount of user interaction. Things happen beyond the user's control, and he encounters progressively more alerts and error messages instructing him how to proceed within the piece. Thus, in parallel with the movement towards newer technologies, the user experiences problems of increasing frequency and fatality until, at last, control is taken completely out of his hands. Interaction turns into reaction, and finally the user is confronted with an "intelligent" entity that is communicating with him by typing chatty messages onto the screen. As this entity discloses all the data it has collected about the user, he realizes that in trying to control the machine, he has ultimately been forced to cede control to it.


SUNLAND, Col., March 4 (AP) -Cottages floating away on rising flood waters, :fi nally rolling over and breaking apart . . . other dwellings smashed to bits by thundering boulders their own men struggled eight miles 0 vel' ridges, through gullies and streams 10 get help for his marooned tellow campers, frightening. We all stayed in one cabin. Nobody slept Wednesday night. Some of us had to go out because our food was running low." Flood Region See Slin After 5 Rainy Day


ABSTRACT Dissodactylusnitidus is a small pinnotherid crab living as an ectosymbiont on the Pacific sand dollars Encope grandis, E. californica, E. micropora, and Mellita longifissa. Larvae of D. nitidus are the first to be described among over 30 pinnotherid species ranging from the Gulf of California to Peru. It is the only known species of Dissodactylus to develop four zoeal stages before metamorphosis to the megalopa. All larval stages are described in detail, including the distribution of chromatophores and types of setae. Beginning with the first zoea, mean duration for each stage was 4.5, 2.6, 3.1, and 3.7 days, with the first megalopae appearing 11 days after hatching. The zoeae of D. nitidus are similar to those of other members of the "large-palped" or major subgroup (D. crinitichelis, D. primitivus, D. mellitae) and are unlike members of the "small-palped" or minor subgroup (D. stebbingi, D. rugatus). Larvae of all species can be separated based on morphometric measurements. The megalopa bears a unique oversize seta on the fifth leg which readily distinguishes it from the corresponding stage of all other species of Dissodactylus.


Objective To determine the value of a three-dimensional ultrasound measurement of the volumes of gestational and yolk sacs and retrochorionic blood flow study in the prediction of pregnancy outcome in the first trimester. Patients and methods Pregnant women in the first trimester were divided into two groups: first group included 50 participants (normal-control group) and second group included 60 participants with a history of two or more abortions in the first trimester. All women had undergone three-dimensional ultrasound measurements of gestational sac volume (GSV) and yolk sac volume (YSV) (using the VOCAL method) and retrochorionic blood flow study. Each patient was examined once and revised after 20 weeks' gestation for the occurrence of normal or abnormal pregnancy progression. Results On comparing data between the cases who continued pregnancy and those who did not in relation to the controls who continued, the GSV showed a statistically significant difference between the three groups, whereas the YSV showed no difference between the three groups. The resistant index of retrochorionic arteries showed a statistically significant difference between the three groups. Conclusion The GSV and the resistant index of retrochorionic arteries were good predictors of pregnancy outcome in the first trimester whereas YSV was not.


This paper investigates millennial scale variability using a long (500 ky) deuterium excess record from an Antarctic ice core. The goal is to identify periods when millennial variability is present in the record, and to draw connections between the occurrence of millennial variability and global ice volume. Finally, the authors suggest a source for this millennial variability via precession-driven changes in atmospheric circulation.


A novel press-fit clamp comprises a floating device and a punch handle, wherein the floating device is formed by assembling a press-fit head, a bushing, a spring, a stop block and a press-fit sleeve; the press-fit head adopts an inner stepped hole and a blind hole and is in clearance fit with the bushing; the bushing is arranged in the press-fit sleeve; the press-fit sleeve is in interference fit with the punch handle; the stop block is arranged in the bottom of the press-fit sleeve; the assembling spring is arranged between the stop block and the press-fit head. During an assembly process, the novel press-fit clamp can correct concentricity between press-fit casings and ensures that products are always concentric during press fit, thereby solving the problem of poor press-fit fastness.


When driving a motor vehicle, one of a driver's basic tasks is to follow a traffic route in such a way as not to endanger other drivers or pedestrians. In order to improve traffic safety, manufacturers install new safety systems in automobiles as soon as they are tested and become available. With this in mind, this paper discusses the recent introduction of an Involuntary Lane-crossing Alert System (ILAS) that warns drivers of unintended and incorrect crossing of a full or broken line during driving. Proper functioning of ILAS requires high quality road markings on the carriageway in order to allow this safety system to accurately identify them in time. Road markings can be defined as a set of longitudinal and transversal lines, signs, and symbols, the combination of which comprise the surfaces of the traffic infrastructure. These road markings represent a part of the entire traffic signalization and cannot be replaced by other markings or regulations. As such, road markings have the task of visually guiding the driver, allowing drivers to be able to forecast the route of their safe movement. Every crossing of a full or broken line at speeds greater than 80 km/h and without an activated indicator is identified by ILAS and the driver is warned by the vibration of the driver's seat.


Recognition by innate immune cells of the pathogen associated molecular patterns (PAMP) lipopolysaccharide (LPS) from Gram‐negative bacteria and bacterial CpG‐DNA depends on Toll‐like receptor4 (TLR4) and TLR9, respectively. To define differences in the response to these distinct PAMP we compared a key intracellular event, namely recruitment of myeloid differentiation marker 88 (MyD88) to the respective PAMP‐initiated TLR signaling. Using MyD88‐GFP fusion protein expressing macrophages we demonstrate that LPS and CpG‐DNA trigger signaling from two different cellular locations: theformer at the cell membrane and the latter at the lysosomal compartment. While LPS does not require endocytosis to functionally associate with the membrane expressed TLR4/MD2 complex, internalization and endosomal maturation is conditional for CpG‐DNA to activate TLR9. In support of these data TLR9 is not localized at the cell surface, but intracellularily. These data stress the need to characterize individual TLR at the very beginning of signal initiation in order to understand their diverse biological functions.


We compare the difference of MA's performance from two aspects,the VAR and the integrated point function model.The results show that horizontal,vertical and conglomerate MA's total market risk raised in the first stages and then decline,and that the three types of MA tend to be equal to the average value of market risk.The performance of MA companies are likely to get better only in the first years.But as a whole,the performance of conglomerate MA is better than horizontal MA and vertical MA.


In February of this year Dr R. Offor retired from his post of Library Adviser to the Inter‐University Council for Higher Education Overseas, and there are many reasons why his retirement calls for special notice. In the first place it closes an unbroken period of library service of some sixty years. This record may have been exceeded in the past—possibly, for example, by Henry Guppy and by B.M. Headicar—but few are likely to surpass it in the future. And Dr Offor's long career has been of great distinction. As a young man he joined the staff of the Library of University College, London in 1901 and remained in that Library, serving under R.W.Chambers, until 1919. Dr Offor was then appointed University Librarian at Leeds, a post which he held until his retirement in 1947 when he was made Emeritus Librarian; and in that same year he was appointed by the Colonial Office as Library Adviser to the Inter‐University Council for Higher Education Overseas.


has disappeared'' (p. 7). In short, it is not just the effects of the Veteran Administration's racism but also the effects of fractured support networks in the inner-city black community that make the situation of many black veterans so dismal. They returned home to distressed communities that lacked the capacity to provide the emotional support and stability they desperately needed. This is an original and insightful use of the collective trauma perspective that captures the social-psychological anguish experienced by not only black veterans but by many black inner-city residents. Steiner's reference to this theoretical perspective should be of interest to other students of contemporary black inner-city communities. Disposable Heroes has several shortcomings that should be noted. First, it needed a stronger development of its theoretical perspective on collective trauma, with more indepth analysis of its broader implications for understanding inner-city black communities. Second, it largely ignored black women—the wives, mothers, and sisters— and how their lives are affected by the problems of the marginalized black veterans to whom they are attached. Third, its sample size is a serious limitation. Life history interviews capture valuable narratives of personal experiences and feelings, but they can only take one so far. There is a need for a larger sample of black veterans in different cities. This is a logical next step, because it is impossible to generalize about black veterans in the Unites States from a study in one middle-sized American city. This study should be seen as a preliminary inquiry which needs to be followed by other studies based on larger samples. Fourth, this study is surprisingly weak in the area of policy proposals. More attention should have been devoted to identifying the political obstacles and recommending measures that should be taken to solve the problems confronting black veterans. These shortcomings notwithstanding, this is a valuable book which calls attention to a serious social problem. It should be of interest to sociologists in the areas of race relations and urban sociology. For Love and Money: Care Provision in the United States, edited by Nancy Folbre. New York: Russell Sage Foundation, 2012. 280 pp. $35.00 paper. ISBN: 9780871543530.


This article proposes a thematic analysis of exiled Russian adolescents' accounts of their memories of the revolution and the civil war. In a body of about five hundred texts, written in 1923 and 1924, the greatest part of the stories were devoted to the sliding of the Great War into civil war, the reversal of the enemy, and the images and scenes that symbolized the overthrow of the power in the eyes of the youngest of the generations witness of the events. The authors of these accounts were mostly the sons and daughters of officers mobilized since 1914. They lived their childhood in a mobilized society with the war forming their familiar universe and their reference to "normality." Their reading of this troubled period marked by the situation of a father stigmatized in the revolutionary upheaval as a representative of the shameful authority carried the decisive mark of the collapse of the Russian army. These memories of the "children of the enemy" correspond to leaving home, wandering throughout the country, and the beginning of exile.


Problems in the planning of water supply for the area with serious fire hazard have been studied. Based on the related regulations and requirements, several functional areas have been classified with the reference to the overall fire hazard arrangement. The uncertainty of fire water supply have been set up according to the uncertainty of burning characteristics of serious fire hazard. Natural water resources within the hazardous area as well as the complementation of the other water supply network have been considered when establishing the multi-purpose function of the amount of fire water supply and pressurized water pump. The related confinements have been defined with considering the occupancy, scale, density of people and hydraulic balance of the pipe network. The optimized fire water supply model has been finally established.


1. Marketing in the aeronautics industry.- 2. The Individual and Organizational Purchase.- 3. Business Marketing Intelligence.- 4. Market Segmentation and Positioning.- 5. Marketing and Sales Action Plan.- 6. Innovation and Product Management.- 7. Marketing of Services.- 8. Pricing Policy.- 9. Selecting Distribution Channels and Sales Team Management.- 10. Project Marketing.- 11. Communication Policy.- 12. Selecting Media.- 13. Brand Management.- 14. Building Loyalty: Maintenance, Customer Training and Offsets.- 15. Alliance Strategies.


Background:Type II CSP is usually treated by surgery, such as transabdominal, transvaginal, hysteroscopic and laparoscopic resection, It takes a long time for contraception,For patients with urgent fertility requirements, the above methods lack advantages,We are trying to find a safe and effective treatment to shorten the time of contraception.Methods: A total of 41 cases of CSP-Ⅱ were selected from January 1, 2019 to June 30, 2020 in the first people's Hospital of Kunshan City, Jiangsu Province,The patients were divided into two groups, group A(20 cases) was laparoscopic continuous inverting mattress suture + suction curettage,Group B(21 cases) was laparoscopic hysterotomy.Group A was compared with group B:serum β-hCG levels on the first day after operation;Inpatient time;time for serum β-hCG levels to return to normal;HGB on the first day after operation;menstruation recovery time;The differences in the intraoperative blood loss;operation time;The decrease rate of serum β - hCG level on the first day after operation.Results: Group A was compared with group B,serum β-hCG levels on the first day after operation,Inpatient time were not statistically significant (p > 0.05);time for serum β-hCG levels to return to normal,HGB on the first day after operation,menstruation recovery time were statistically significant (p < 0.05),Group A was significantly higher than group B;The differences in the intraoperative blood loss,operation time were significant difference between the two groups (P < 0.05),Group A was significantly lower than group B;The level of serum β - hCG on the first day after operation decreased by 50% in both groups.In group B, the pathology of the excised scar muscle layer showed that there was a little villus tissue in the muscle layer, and a large number of trophoblast cells were seen between the fibrous smooth muscle tissues.Conclusions: In group A,the method is more simple, less bleeding, shorter operation time and less trauma;it also can remove the diverticulum and increase the thickness of the lower uterine segment;the contraception time was shortened,but the decrease of serum β - hCG was slow and the recovery time of menstruation was long.


At this time the earth is being hit by the Corona Virus pandemic which has resulted in a lack of direct interaction in services and in the field of immigration, especially in reporting services for immigration permits for transportation equipment / ships. This situation has the potential to be exploited by unscrupulous individuals to carry out unscrupulous acts such as extortion and other things. Then the immigration office made an innovation, namely the application of the Port Transport Equipment Immigration Permit Reporting Information System, which was abbreviated as Sili Laba. The aim of the researcher was to determine the profile of the Sili Laba application, and the effect of the Sili Laba Innovation Strategy on the performance of the Class II TPI Belawan immigration office. In this study using quantitative methods. And the results of the research based on the regression test show that Y = 37.549 + 0.331X which states that for every additional 1 value of the innovation strategy, the performance value will increase by 0.331. Based on the results obtained from the above equation, the calculated t value is greater than the t table value, which is 6.064 > 2.021. So, from the results of the above equation it can be concluded that there is an influence given by the innovation strategy variable (X) on the performance variable (Y).