Ink jet printhead chip includes a substrate. The drive circuit is located within the substrate. A plurality of nozzle devices are disposed on the substrate. Each nozzle apparatus comprises an ink ejection nozzle chamber walls (walls) and loop port in the wall that forms the loop wall that fluidly communicates with the nozzle chamber with the nozzle chamber. Ink pusher (pusher), in order to eject ink from the ink ejection port, and the work position with respect to the nozzle chamber is displaceable in the range of between 1 micron and 5 microns. Actuator (actuator) receives the electrical signal from the drive circuit in order to displace the ink pusher and is connected to the driving circuit and the ink pusher.


This paper contains a theoretical and numerical investigation of the incremental formulation for the mean-field homogenization of two-phase elastoplastic composites. We study several variants of the formulation and try to understand why some of them give good predictions while others do not. We define six instantaneous operators for a fictitious homogeneous reference matrix (two anisotropic, two isotropic, and two transversely isotropic) and various estimates of the macroscopic tangent operator. Theoretically, we present mathematical results that prove that some estimates are stiffer or softer than others. Numerically, we carry out a wide range of validated simulations with different types of inclusions under various loads. The findings confirm the theoretical results and shed new light on a rather complicated problem.


General practitioner Newport, Gwent (b 1946; q Bristol 1968; FRCOG), d 11 May 2006.

John Dodoo's second home was Newport, where he worked for 31 years. After obtaining the MRCOG he spent two years at Norfolk and Norwich and three at Korle Bu University, Accra. Returning to Newport and general practice, he soon became senior partner and masterminded its refurbishment. He maintained his expertise in obstetrics and gynaecology with regular sessions in clinics, operating, and on the labour ward. He showed his love of the specialty and the Royal Gwent Hospital by developing the Park Assessment Unit for antenatal care there. He leaves a wife, Kathy, and two daughters.


Traffic of goods within the legal scope imposed by the will of the particulars is a core issue of interest, not only to the contract parties but to everyone, particularly to the transferor/acquirer creditors and to third parties acquiring rights on the goods. The scope of this work is to analyze the transfer of goods regime "inter vivos" within the Spanish Law, within the European legal scope and with emphasis on the real state transfers. Spain has adopted a peculiar transfer system, due to the fact that general rules apply notwithstanding the immovable or movable nature of the good, and, additionally, other rules are superposed intending to establish the effects that derive from the real state register publicity. The coordination between the above-mentioned rules produces an original result that may constitute the meeting point of different European register systems.


Background: BAY 81-8973 is an investigational recombinant factor VIII (FVIII) product with recommended prophylactic dosing of 20-40 IU/kg at least 2x or 3x weekly for patients with severe hemophilia A. The frequency of dosing with FVIII is among several decisions made by treating physicians and potentially affects effectiveness and cost. The impact of prior bleeds or prior FVIII treatment on the choice of BAY 81-8973 dosing frequency has not been studied previously and may help clarify the association of dosing frequency with effectiveness. This study examines the association between prior treatment patterns and bleeds with dose frequency assignment in patients from the LEOPOLD I (LEO I) trial. Methods: Data from part B of the phase II/III randomized, open-label crossover LEO 1 trial were analyzed. The sample consisted of patients who received prophylactic treatment with BAY 81-8973 during the 12-month LEO I study period. At study start, patients were assigned to a dose and a frequency of either 2x/week or 3x/week at the investigator9s discretion; once assigned, the dose and frequency were unchanged through the study period. This analysis compared physician-recorded pre-enrollment FVIII treatment frequencies and bleeds during the last 12 months prior to enrollment between the 2x/week and 3x/week groups. Wilcoxon rank sum tests were used to compare average dose per FVIII injection and number of bleeds, and chi-square tests were used for mode of treatment (on-demand or prophylaxis) and FVIII treatment frequencies. Results: Among 62 patients in the trial, mean age was 31.5 years and 89% were Caucasians. FVIII prophylaxis frequencies ranged from daily to 1x/week prior to enrollment. 11 patients in the 2x/week group had received pre-enrollment FVIII prophylaxis at a frequency of 2x/week (Table 1). 28 patients in the 3x/week group had received FVIII injections at a frequency of 3x/week prior to enrollment. Some of these patients in each group had also received pre-enrollment FVIII prophylaxis at other frequencies. Average FVIII doses per injection in IU/kg were higher in the 2x/week group for prior on-demand and prophylactic therapy, but these differences were not statistically significant. The majority of patients in the 2x/week group (56%) and the 3x/week group (59%) had received Bayer9s sucrose-formulated recombinant factor VIII prior to enrollment. Regardless of prior mode of treatment, the average number of bleeds in the last 12 months before enrollment was higher in the 3x/week group (13.4 bleeds) than in the 2x/week group (7.1 bleeds). Conclusions: Investigator selection of 2x/week or 3x/week dosing frequency was correlated with the regimen patients were on prior to enrollment. Patients receiving FVIII 3x/week had, overall, more frequent bleeding episodes than patients in the 2x/week group in the year prior to enrollment, suggesting that a phenotypic approach can well be used for dosing with Bay 81-8973. Disclosures Church:Bayer Healthcare Pharmaceuticals: Employment. Ayyagari:Bayer Healthcare Pharmaceuticals: Consultancy, Research Funding. Pocoski:Bayer Healthcare Pharmaceuticals: Employment. Sajeev:Bayer Healthcare Pharmaceuticals: Consultancy, Research Funding. Kelkar:Bayer Healthcare Pharmaceuticals: Consultancy, Research Funding. Du:Bayer Healthcare Pharmaceuticals: Consultancy, Research Funding. Mass-Enriquez:Bayer Healthcare Pharmaceuticals: Employment. Xie:Bayer Healthcare Pharmaceuticals: Consultancy, Research Funding.


The Hanford Environmental Dose Reconstruction (HEDR) Project has developed a set of computational ``tools`` for estimating the possible radiation dose that individuals may have received from past Hanford Site operations. This document describes the planned activities to ``validate`` these tools. In the sense of the HEDR Project, ``validation`` is a process carried out by comparing computational model predictions with field observations and experimental measurements that are independent of those used to develop the model.


We present a reduced-order model (ROM) methodology for inverse scattering problems in which the reduced-order models are data-driven, i.e. they are constructed directly from data gathered by sensors. Moreover, the entries of the ROM contain localised information about the coefficients of the wave equation. We solve the inverse problem by embedding the ROM in physical space. Such an approach is also followed in the theory of ``optimal grids,'' where the ROMs are interpreted as two-point finite-difference discretisations of an underlying set of equations of a first-order continuous system on this special grid. Here, we extend this line of work to wave equations and introduce a new embedding technique, which we call Krein embedding, since it is inspired by Krein's seminal work on vibrations of a string. In this embedding approach, an adaptive grid and a set of medium parameters can be directly extracted from a ROM and we show that several limitations of optimal grid embeddings can be avoided. Furthermore, we show how Krein embedding is connected to classical optimal grid embedding and that convergence results for optimal grids can be extended to this novel embedding approach. Finally, we also briefly discuss Krein embedding for open domains, that is, semi-infinite domains that extend to infinity in one direction.


A coplanar waveguide‐fed monopole antenna with split ring resonator (SRR) loaded substrate is introduced to obtain good impedance matching over a wide band of frequency. SRR is loaded on the backside of the substrate used to obtain a wideband covering from 3.87 to 7.63 GHz, which covers the 5 GHz WLAN and 5.8 GHz RFID applications. The size of the antenna is 31 × 24.57 × 1.6 mm3. A prototype of the proposed antenna has been fabricated and measured. The radiation pattern measured at resonance is omnidirectional in the H‐plane and bidirectional in the E‐plane. Details of the proposed antenna design and measured results are presented and discussed. The measured peak antenna gain is 2.51 dBi. SRR characteristics are also discussed to validate the results and parametric study of SRR is also done. © 2014 Wiley Periodicals, Inc. Microwave Opt Technol Lett 56:2388–2392, 2014


In order to facilitate compression of a positive ion charge bunch longitudinally and transversely beyond the limit determined by the space-charge field of the bunch, a source of charge-neutralizing electrons must be provided. Plasma sources have been developed for the NDCX-I and NDCX-II experimental facilities, both for the 2-m-long, field-free drift regions and for the small-diameter interior of the multiTesla final focus solenoid. Barium titanate based cylinders with a high dielectric coefficient are used to line the wall of the 2-m-long drift region, and by applying a 9 kV pulse between the inner and outer surfaces of the cylinders, a plasma with a density in the 10 cm range is formed. A compact plasma source 2" long and 1.5" in diameter, also made using the barium titanate based material, has been developed for use in the bore of the final focus solenoid. Plasma generated near the wall of the plasma source will follow the fringing magnetic field lines of the solenoid and help to fill the bore of the magnet with plasma. Improved designs for the barium titanate plasma sources are being considered that use different inner-surface electrode materials and structures, and also use a modified electrical driver employing a spark gap crowbar switch. In addition, plasma source designs using so-called flashboard technology have been developed. In the flashboard plasma source, high density plasma is formed when the applied high voltage pulse causes a series of breakdowns between isolated copper patches aligned in rows along the surface of the 0.2 mm thick flashboard.


PURPOSE: To obtain a new vector useful for obtaining a desired polypeptide used as a medicine, etc. CONSTITUTION: This vector has an inducible selection gene and a sequence encoding a heterologous polypeptide. A duplicable plasmid expression vehicle has an inducible selection gene comprising e.g. tetA and tetR (tetracycline) and a DNA sequence encoding the heterologous polypeptide. The vector capable of synthesizing the desired polypeptide is obtained by inserting the sequence encoding the desired polypeptide into a proper insertion site in the vector. COPYRIGHT: (C)1993,JPO


OBJECTIVE
To examine the understanding of the reporting criteria of Hepatitis B (HB) and Hepatitis C (HC) of the medical staff in Yanbian Korean Minority autonomous prefecture and provide the advice for reporting HB and HC via network.

METHOD
Questionnaires were distributed to doctors in 7 hospitals by the method of stratified sampling.

RESULTS
48.3% of the medical staff thought that HBsAg carries should also be reported; The understanding of the reporting standards of HB and HC correctly was only 41.4% and 66.4% respectively. The understanding of the reporting standards of HB was different among professional staff in municipal hospital and in county-level hospital, which was lower at the municipal hospital; the reason for misunderstanding is mainly concentrated in HBsAg carriers as the report object; there was not difference of the understanding to the reporting standards of HB and HC among different title and work experience.

CONCLUSION
The medical staff among investigated hospitals had lower knowledgement to the reporting standards of HB and HC. Vigorous training should be conducted according to the criteria of hepatitis diagnosis, to ensure that the epidemic situation of HB and HC science and accuracy.


The paper begins with a presentation of the past 20 years Hungarian accident statistics together with attempts to analyse these figures. Following an international comparison the author tries to identify the most effective accident countermeasures of the nineties. Finally, some recommendations to improve the efficiency of accident prevention are provided. For the covering abstract of the conference see IRRD E201756.


Dispersing the single load of shield machine to 400 t hydraulic trailer group by loading bearing underprop and uniformly loaded beam,the first integer transportation of shield machine comes through by rigorous construction.


Welcome and Overview of the DayPresentation by: Kirsty MacLachlan, Head of Demography, General Register Office for ScotlandThe Silver EconomyPresentation by: John Lawson, Head of Pensions Policy, Standard Life Assurance LimitedPlanning for a Scotland with an Ageing PopulationPresentation by: John Storey, Head of the Older People and Age Team, The Scottish GovernmentModelling Ageing Populations to 2030Presentation by: Professor Mike Murphy, London School of EconomicsDesign, technology and independence: getting research into policy and practicePresentation by: Professor Peter Lansley, Reading UniversityInternational Perspectives on Healthy Independent AgeingPresentation by: Professor Jane Falkingham and Professor Maria Evandrou, Southampton UniversityCentre for Population Change and other related projectsPresentation by: Professor Paul Boyle, University of St Andrew's


Earlier literature has analysed regional finance gaps by comparing metropolitan areas with peripheral areas on a relatively high level of aggregation and most often in a U.S. or U.K. venture capital context. Financial capital has been found to be concentrated in metropolitan areas and access to capital easier because en-trepreneurs leverage on proximity to capital providers. However, regardless of whether it is metropoles, when there is an urban centre of a certain size or relative dominance in a region, it can be hypothesized that financial capital is likely to be attracted to this urban centre even within a peripheral region. The literature has been silent regarding financial ?centres' within peripheral areas. Survey responses from managers in 834 firms are used in the empirical analyses. We find indications of differences in whether firms are financially constrained depending on the levels and types of geographical aggregation that are used in the models. In other words, even within the periphery there is a periphery-core difference. Intra-regional differences accen-tuate the need for considering the appropriate regional level of policy making and the policy instruments. The paper contributes specifically to the analysis of geographical scale in regional financial constraints. The issue of scale is in the core of economic geography yet often disregarded both in research and in the pro-cess of designing regional policies. On a general level of aggregation it contributes to a better understand-ing of regional policies for financing entrepreneurship and innovation.


The austrian habsburg court under Empress Maria Theresa has been characterized as combining an informal domesticity with a rigid ceremonial structure inherited from her predecessors. In this picture of life at the Habsburg court, the strict protocol and elaborate calendar of ceremonies only partially designated how the imperial family structured its time; protocol and ceremony coexisted, it would seem, with more casual and relaxed forms of familial interaction. Popular Austrian writing on Maria Theresa has stressed the image of the empress as mother, and the maternal quality of this portrait has colored some modern notions of how her palaces were occupied and used. Tourists visiting Schönbrunn palace, for example, are often told that many of its rooms were designed with familial contact in mind, and the resulting picture of the palace's use and habitation is curiously modern. The notion that an "imperial domesticity" governed actions at Maria Theresa's Schönbrunn has found its way into scholarly literature as well; one scholar has gone so far as to describe Schönbrunn's admixture of ceremonial and intimate spaces as vorbiedermeierlich, that is, prefiguring the family-oriented, bourgeois culture of nineteenth-century Vienna. The instigator of this myth may be Stefan Zweig, who in 1932 described Marie Antoinette's childhood at Schönbrunn as one filled with carefree play, personal freedom, and adventure, all of which prepared her inadequately for her future role as queen of France. The modern visitor to Schönbrunn might be forgiven for thinking that, despite the palace's sumptuous rooms and elegant decoration, it differs minimally from the modern single-family home.


ABSTRACT Public-facing social media platforms, such as Facebook and WeChat, are increasingly being embedded into corporate processes and routines. The use of public social media by employees has aroused widespread interest among scholars in recent years. This study summarises published theories and models and proposes a causal-chain framework for research exploration into employee usage of public social media platforms by systematically analysing the antecedent variables, mediators, moderators, and outcome variables used in 59 quantitative papers. The representative theories include: Social Capital Theory, Job Demands-Resources Model, Boundary Theory, Media Synchronicity Theory, Social Cognitive Theory, Technology Acceptance Model, Self-Determination Theory, and Media Richness Theory. Historically, researchers have studied social media usage behaviours as antecedents, rather than social factors, with many focusing on outcome variables such as job performance and job satisfaction, while the impact of employee social media usage on physical and mental health is less studied. In terms of moderators, variables such as use behaviour, user characteristics and job characteristics receive most attention. With regards to mediators, social capital, job satisfaction, and work conflict are most significant. This study proposes future research directions for this field, including topics relating to platform attributes, social power, organisational culture, and employee health.


Yunnan Province is one of the most widely distributed and Karst rocky desertification serious provinces in China,and Wenshan is the most serious rocky desertification in Yunnan Province. The mode of governance,harm,causes of rocky desertification were summarized,so as to provide guidance and reference significance to the rocky desertification prevention and control in Wenshan area and Yunnan Province.


We consider the parallel machine scheduling problem of minimizing the sum of quadratic job completion times. We first prove that the problem is strongly NP-hard. We then demonstrate by probabilistic analysis that the shortest processing time rule solves the problem asymptotically. The relative error of the rule converges in probability to zero under the assumption that the job processing times are independent random variables uniformly distributed in (0, 1). We finally provide some computational results, which show that the rule is effective in solving the problem in practice.


Objective: To study the effect of penetration enhancers on the in vitro transdermal permeation of dl-praeruptorin A(Pd-Ia) through rat skin.Methods: The permeation experiments were evaluated by Franz diffusion cell in excised rat skin.HPLC-UV method was established to determine the concentration of Pd-Ia in receptor compartment.Azone or 1% Azone combined with propylene glycol(PG) as chemical penetration enhancers were applied to study the skin permeation rates of Pd-Ia.Results: 1% Azone alone achieved the highest penetration rate,4.064 μg·cm-2·h-1.1% Azone combined with 15% PG was the best penetration enhancer with the maximal penetration rate of 4.889 μg·cm-2·h-1.Conclusion: Combination of 1% Azone with 15% PG is effective on transdermal permeation of Pd-Ia in vitro,and the combination exerts a synergistic effect.


estimator make best use of the data? We show that this is not so and construct better estimators. We restrict attention to nearest-neighbor random fields and to Gibbs samplers with deterministic sweep, but our approach applies to any sampler that uses reversible variable-at-a-time updating with deterministic sweep. The structure of the transition distribution of the sampler is exploited to construct further empirical estimators that are combined with the standard empirical estimator to reduce asymptotic variance. The extra computational cost is negligible. When the random field is spatially homogeneous, symmetrizations of our estimator lead to further variance reduction. The performance of the estimators is evaluated in a simulation study of the Ising model.


The Station logo is a way for a TV station to claim copyright, which can realize the analysis and understanding of the video by the identification of the station logo, so as to ensure that the broadcasted TV signal will not be illegally interfered. In this paper, we design a station logo detection method based on Convolutional Neural Network by the characteristics of the station, such as small scale-to-height ratio change and relatively fixed position. Firstly, in order to realize the preprocessing and feature extraction of the station data, the video samples are collected, filtered, framed, labeled and processed. Then, the training sample data and the test sample data are divided proportionally to train the station detection model. Finally, the sample is tested to evaluate the effect of the training model in practice. The simulation experiments prove its validity.


Ovine abortion is a worldwide problem for sheep farmers, and can have a variety of infectious and non-infectious causes. The most notable infectious causes are Chlamydia abortus and Toxoplasma gondii, but there are a range of pathogens known to farmers and vets. Diagnosis is achieved by post-mortem examination of aborted lambs and testing of samples including, but not limited to, the foetal membranes and placenta. There are several efficacious vaccines available in the UK targeting abortion-associated pathogens, mainly to be administered before mating. Vaccine uptake is variable, and more emphasis on farmers complying with protocols needed.


As we prepare to cross the bridge to the twenty-first century and to a new millennium, there is much analysis of the state of Catholicism in the United States. While the number of Catholics continues to increase, much of the analysis continues to focus on institutional decline, particularly of the priesthood and religious life and institutions dependent on them, such as schools and parishes. However, another phenomenon, more difficult to measure but equally alive in Catholic culture, is that of a spiritual resurgence. While there is clear evidence that there is a disjuncture between religion and spirituality in the thinking and behavior of some in the society, this article speculates about Catholicism in the United States in the twenty-first century as a spiritual-institutional church that weaves spiritualities through institutions in new, and old, ways. New tools will be needed for the analysis of the construction of spiritual cultures within and outside of Catholic institutions and the responses of generational cohorts to elements of those cultures.


We have developed an on-line system to aid in the management of enclosed, multi-tank fish farms with water filtration, heating and recirculation, where fish are grown from fingerling through to market size (about 250 gr.). The manager has a high degree of control over tank loadings and fish rearing conditions, but he must maintain high production rates within biological constraints on water quality and fish density and within system constraints imposed by the physical plant. A multi-level interactive simulator permits exploration of management strategies, with nested levels of constraints. A database is used for storage of both real and simulated data on management interventions and their consequences on fish growth and water quality. Interaction between the simulators and the database aids model calibration and validation and permits storage of promising management strategies.


This study focuses on 171 university students' level of knowledge, perceptions and practices regarding Zika virus and its vector in Santa Marta (Colombia) in 2016. A survey was conducted and answers about causative agent and mode of transmission were classified into three levels of knowledge. 32.1% of the students stated that they had suffered from Zika. A 60% stated that they knew what the disease was, however, only 29.2% knew what the causative agent was and 45.6% knew the mode of transmission. Regarding the level of knowledge, only 14.6% knew the causative agent and the mode of transmission (Level 2). In general, the students recognize Zika's symptoms, and 53.8% consider Zika to be very serious and more than half consider that they, the community and the government are responsible for controlling the vector. Even though more than half the students know the most important strategies as regards on how to control the vector, they do not practice them; this may be explained by the characteristics of their daily live dynamics, the lack of community organization, deficiency in the system of public health and climate change. It is recommended to implement permanent vector control strategies that consider the sociocultural characteristics of at-risk populations.


A field trial was carried out to control the 3ndinstar larvae of P. xylostella on the cabbage B. chinensis by the I. fumosorosea strain RCEF3423. The results showed the mortality and infection ratio of P. xylostella larvae reached 82. 67% and 64. 80% respectively in the treated plots of 1 × 107conidia / mL. The other plots treated with the concentration of 1 × 108conidia / mL gained the mortality and infection ratio of 90. 67% and 76. 27%. The I. fumosorosea strain RCEF3423 has greatly significant effect against P. xylostella larvae,which shows great potential for development.


time of operation before caudal pancreaticojejunostomy was begun. However, it was reasoned that the calcinosis was secondary to obstruction initially and that removal of the stones alone might well be followed in the future by further episodes of obstruction. Accordingly caudal decompression was performed. (We are experimenting with methods to prove postoperatively the patency of the pancreatic enterostomy by roentgenographic means, thus far unsuccessfully.) Since the majority of patients with chronic pancreatitis show pronounced evidence of obstruction, it seems reasonable that this relatively simple approach to the treatment of this benign crippling disease should be further pursued. Only after a period of years can the value of the procedure be assessed. While undoubtedly there will be occasional failures, it would appear from early reports that with careful selection, and rejection of cases not meeting rigid criteria for obstruction, the number of poor results should be minimal. In any event it seems that this operation may well become the procedure of choice in the treatment of severe chronic pancreatitis.


Effects of daylength and temperature on the formation of erect macrothalli from crustose microthalli tf Dumontia contorta from Roscoff (49° N.lat.), the Isle of Man (54° N.lat.) and Zeeland (51.5° N.lat.) were investigated. Initiation of macrothalli in all three strains appeared to be a short-day response whose critical daylength, however, differed between the three strains. In the Isle of Man and Roscoff strains the critical daylength was c. 12-13 h, in the Zeeland strain c. 16h. This latter high value does not seem to have adaptive value to the latitude where this strain occurs. The three strains also differ in the temperature ranges in which macrothalli were formed (Roscoff strain up to 20 °C, Isle of Man strain up to 16 °C, and Zeeland strain up to 24 °C), and these could be related with the highest values of the surface seawater temperature at the three collection sites (Roscoff 16 C, Isle of Man 14 °C, Zeeland 19 °C). The response to short-day conditions was suppressed by short white light night-break, and a red and blue light nightbreak are equally effective. Far-red proved to be ineffective. The short-day response of Dumontia contorta is compared with that ofAcrosymphytonpurpuriferum and other taxonomically related species.


Based on Tian Yu's Fuyin garden drawing in the mid-19th century and the image data left over from the garden in the same period, this paper studies it by using the coordinate reduction method and perspective reverse method respectively. The former uses the coordinate reduction method to restore the overall layout and spatial location of the Fuyin garden based on the boundary painting attribute. The latter uses the perspective reverse method to obtain the data of spatial layout and building size of different locations Fuyin garden based on photorealism. The two are pieced together, integrated, verified, and corrected in an attempt to realize the restoration conjecture of the Fuyin garden. The research contents include image data collection, image contour extraction, and vectorization, image perspective reverse, multi-view matching analysis, verification, and correction.


The chemical structure of adenosine 3',5'-monophosphate, otherwise known as cyclic AMP, is shown in FIGURE 1. It was discovered as the mediator of the hepatic glycogenolytic effect of epinephrine and glucagon,' and is now recognized as a versatile regulatory agent mediating a host of hormonal effects.2 Research in this area is expanding at such a rate that it is very difficult, if not impossible, for a single group to keep track of it all. Our hope for this present monograph was that it would update and supplement an earlier one,2 which we hope will continue to be useful as a source of background material. Both of these hopes will probably be realized to some extent, but the incredible pace of research in this area cannot be overemphasized. We are writing these words in October, 1970, with the conference less than a month away, and we fully expect that they will have a faintly old-fashioned ring to them by the time they are in print. Perhaps by extrapolating from what is said here and in the rest of this monograph, the serious reader will gain at least some idea of where the subject is likely to lead in the future. The structure of adenyl cyclase is still poorly understood. Information about this enzyme was summarized previously,".' and an important recent development is discussed in this monograph by Lefkowitz et Still more recently, Rodbell and his colleagues 6 * have made some useful contributions. There is no longer any question that the receptors for some hormones are very closely related to the adenyl cyclase system as a whole, but most of the details remain to be worked out. We still do not know how the hormone-receptor interaction leads to a change in the catalytic activity of the enzyme. To whatever extent our earlier model (FIGURE 2) represents an aspect of reality, it would appear that the catalytic and regulatory subunits do not necessarily develop at the same time. A more operationally correct way of summarizing the available data R , would be to say that the catalytic activity of adenyl cyclase and its ability to be stimulated by hormones do not necessarily develop at the same time. There is now evidence that these two components of the system can be separated,*O and further work along these lines will be watched with interest. The suggestion that GTP or GDP may play an important role in the effects of hormones on adenyl cyclase has also been of interest, but whether future research will substantiate or invalidate this hypothesis remains to be seen. The detrimental effects of cell breakage on adenyl cyclase, and especially on its sensitivity to hormonal stimulation, were emphasized in an earlier review.J However, we can now see that this may be even more variable than it was then thought to be. Platelet adenyl cyclase, for example, seems to be just as sensitive to stimulation by prostaglandins in broken cell preparations as it is in intact cells, as noted by Krishna and his colleagues.ll Brain cyclase stands at the other end of the scale, with most other cells and tissues falling some-


The invention discloses a train-tail independent frequency-point broadcasting station and a control method thereof. The broadcasting station comprises a locomotive, a locomotive antenna and a train-tail main machine which is communicated and connected with the locomotive in a wireless way as well as a train-tail main machine antenna; the locomotive comprises an independent frequency-point train-tail locomotive station which is installed in an equipment room, a first control box, a second control box and a power supply, wherein the first control box and the second control box are respectively installed in a first cab and a second cab and are connected with the independent frequency-point train-tail locomotive station, and the power supply is respectively connected with the first control box, the second control box and the independent frequency-point train-tail locomotive station; and the locomotive antenna is arranged on the independent frequency-point train-tail locomotive station. Due to the adoption of the train-tail independent frequency-point broadcasting station and the control method, the weaknesses of the prior art that the communication interference phenomenon is serious, the reliability is low, the universality is poor and the like can be overcome, and the advantages that the interference of original radio train radio-frequency-point can be avoided, the reliability is high and the universality is strong can be realized.


Newsletter "issued monthly during the regular session, and once during the summer session by the students in the Department of Library Service, North Texas State College, Denton, Texas" (p. 33). The periodical contains news items; announcements; a schedule of Fall courses; a Library Service Department Directory; and personals concerning students, faculty, staff, and alumni.


Childhood hypertension (HTN) is important cause of morbidity and mortality. Most of the cases of childhood HTN are secondary to an underlying disorder. In this case report a ten & half yr old boy presented with neck pain associated with headache. Both of his parents are hypertensive. Most of the time he spent at home playing games in computer and watching television. On examination, blood pressure (BP) was 140/95 mm of Hg which was above 99th percentile for his age and height. Examination of eyes and other systems revealed normal. Ultrasonography of abdomen was normal, colour Doppler ultrasonography of renal vessels showed normal, and CT scan of abdomen was also normal including normal adrenal gland and sympathetic chain. Then the child was treated with tab. losartan potassium, then gradually BP become bellow 90th percentile. Ultimately the child was discharged when his blood pressure was 100/70 mm of Hg, which was on 50th percentile with counselling and advised for follow up. DOI: http://dx.doi.org/10.3329/jssmc.v5i1.16253 J Shaheed Suhrawardy Med Coll, 2013;5(1):69-71


This paper deals with the prediction of the fatigue life of composite laminates subjected to service loading spectra. Assuming that the spectrum loading is a Gaussian stationary and ergodic process, a model that predicts the fatigue life is proposed. This model requires the results of the constant amplitude fatigue test and is based on a combination of the Palmgreen-Miner damage rule and the peak-counting method to define and count the cycles. To compare the model predictions to experimental results, random loading was simulated in three different manners: block programming, random sequence block programming and individual cycles method. It is shown that the three simulation methods agree reasonably well with the experimental results: however, the best agreement is obtained with the individual cycle simulation method. All the constant amplitude and random fatigue tests were performed in three point bending on a digitally controlled servohydraulic fatigue machine that permits random simulation. The material used is a quasiisotropic graphite epoxy composite [± 45/0/90] 3s .


A 12-year-old castrated male mixed breed cat was presented to the University of Illinois Veterinary Teaching Hospital oncology service for evaluation of a progressive gait abnormality of 4 months duration. The referring veterinarian identified radiographic evidence of vertebral lysis before referral. Initial physical examination indicated a slightly overweight (body condition score [BCS] 7/9; 4.8 kg) cat with a systolic sternal grade III/VI heart murmur, with all other findings being normal. Computed tomography identified a large, mildly enhancing, expansile, soft tissue attenuating lesion within the vertebral canal of L5, L6, and L7 vertebral bodies (Fig 1). The expansile nature of the mass was evident by the circumferentially widened vertebral canal of L6 and L7, with moderate distortion, and thinning of the pedicles and dorsal lamina. The mass could be seen exiting a markedly widened left L7-S1 intervertebral foramen and extending ventral to the sacrum as the L7 left spinal nerve. It tapered to an abnormal size as it crossed the ischial body forming the sciatic nerve. Inspection of the left gluteal muscles showed moderate atrophy compared to the contralateral pelvic limb. Eight days after the initial CT study, the cat was referred to the neurology service for further evaluation and diagnostic testing. The neurologic examination showed evidence of a plantigrade stance in the pelvic limbs (left more severe than the right) and mild paraparesis in the pelvic limbs bilaterally. The cat had proprioceptive deficits in the left pelvic limb with a decreased withdrawal reflex on the left and mild to moderate pelvic limb muscle atrophy. A large bladder was palpated. No other abnormalities were observed on neurologic examination. A neurolocalization of some combination of spinal cord segments, nerve roots and nerves of L4-S3 (left lateralized) was suspected. Based on the CT findings, neoplasia was the most likely differential diagnosis with peripheral nerve sheath tumor or round cell neoplasia considered most likely. The cat was prepared and anesthetized for the magnetic resonance imaging (MRI); imaging included T2-weighted, T1-weighted and Short tau inversion recovery (STIR) sequences in all 3 planes, as well as repeated T1weighted sequences following contract administration. Magnetic resonance imaging (MRI) confirmed the mass extended from the midvertebral canal of L5 to the L7 spinal nerve root entering the pelvic canal (Figs 2, 3, 4A), with similar expansile changes to the L6 and L7 vertebral bodies. The mass lesion was homogenous and hyperintense on T2-weighted and STIR sequences compared to normal spinal cord seen cranial to L5 (Figs 2, 3). The mass was isointense on T1-weighted sequences with strong homogenous contrast enhancement (Fig 4A,B). The mass obliterated the cauda equina which was only identified caudal to the lumbosacral junction. It also had indistinct margins and displacement of the conus medullaris. A mixed intradural and infiltrative parenchymal mass was diagnosed. Concurrent thickening and contrast enhancement of the urinary bladder was identified that had not been appreciated on the initial CT scan. Based on the imaging characteristics, the differential diagnoses included a peripheral nerve sheath tumor or round cell neoplasia, such as lymphoma or histiocytic sarcoma. Neuritis was considered less likely given the marked expansile nature of the lesion. The findings also suggested a neurogenic bladder and suspected disruption of colonic innervation causing fecal retention. However, the owner reported the cat to have normal urination and defecation at home. The next week, the cat was admitted to the neurology service for surgical biopsy and subtotal resection of the From the Department of Pathobiology and Veterinary Diagnostic Laboratory, College of Veterinary Medicine, Urbana, IL (Rivard, Zhang, Lezmi); and the College of Veterinary Medicine, Veterinary Teaching Hospital, University of Illinois, Urbana, IL (Hague, Joslyn). Corresponding author: D.W. Hague, College of Veterinary Medicine, Veterinary Teaching Hospital. University of Illinois, 1008 W. Hazelwood Dr., Urbana, IL 61802; e-mail: firstname.lastname@example.com Submitted October 11, 2015; Revised December 4, 2015; Accepted January 4, 2016. Copyright © 2016 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. DOI: 10.1111/jvim.13835 Abbreviations:


Global industry requires resilience and adaptability to match the new fluid necessities of 21st Century reality. Learning as a finite suite of knowledge and skills at university to prepare for a static career is now anathema, with industry demanding constant new insight and innovation to meet the needs of an ever-changing global society. In the case of initial teacher education, however, programs that purposefully develop these capabilities are not prevalent, with knowledge and skills sets too often being presented as script and thus reinforcing static thinking and teaching practices. This paper explores qualitative data collected across a network of globally focused secondary schools in Denmark and presents a positive approach for cooperative work-integrated education (CWIE) educators and institutions in initial teacher education that is based on the explicit modeling of learning dispositions. Importantly, the approach can also be seen as being the basis for any practice across professional fields where resilience and adaptability are essential.


Two new computationally viable algorithms are proposed for partial pole-placement and eigenstructure assignment in damped gyroscopic matrix second-order systems. The algorithms can be implemented with only a partial knowledge of the spectrum and the corresponding eigenvectors of the associated open-loop quadratic matrix pencil. Mathematical results are proved to guarantee that there will be no-spillover effects; that is, it is shown mathematically that the large-number of eigenvalues and eigenvectors that need to remain unchanged will not be effected by feedback. Furthermore, the algorithms work directly in second-order setting allowing them to exploit structures such as sparsity, band, symmetry etc. These practical features of the algorithms make them ideally suited for real-life applications such as control and stabilization of large flexible space structures.


•  A previous study showed that an older age could be associated with a lower risk of severe altitude‐induced diseases. •  This work combines a cross‐sectional study including 4675 subjects and a longitudinal study on 30 subjects. •  It shows that ageing is associated with a blunting of cardiac chronotropic function and an increase in ventilatory response leading to maintenance of arterial O2 saturation in hypoxia. •  These adaptive responses to hypoxia with ageing are blunted by menopause but can be maintained with endurance training. •  The cardiac and ventilatory adaptations allow older people to challenge hypoxia similarly to younger ones when performing moderate exercise.


In this paper we described the generic design of software interoperability modules for vertical handover in wireless hybrid access networks. The proposed approach conforms to the IEEE 802.21 Media Independent Handover (MIH) standard and fits into our architecture for reconfigurable interoperability of wireless communication systems, RIWCoS. The next step of our work will be the implementation of concrete media dependent modules following the proposed approach, and their integration into the overall system.


In this paper I present the collective experience of a group of women that runs a community library in the neighborhood of La Sirena in the city of Neuquen. I set the framework of this experience in two contexts: globalization and the particular stage in the life of each of the women involved. The first one allows to see how the local area, the neighborhood, is resignified as a microworld as well as the role that women play in it; the second allows to look into how each one builds her identity as a woman in relation to volunteer and free work and how they deal with the changes imposed both by today's world and by the "second life of women." From the dialogue between these two contexts there arises a tension between what is public and


Good afternoon. I think you can take note of the fact that I'm the last speaker. And so since there is no one to follow me, I am permitted, indeed expected, to follow the rule of the three B's. That is to be direct, be brief, and be seated. I have chosen today to speak about Judge Harold Stevens. I'm sure you're aware of the significance of Judge Stevens to the Court of Appeals because he was, indeed, the first African American Judge to ever sit on the Court. You will note that he sat on the Court for one year. The year was 1974. And he had been appointed by Governor Malcolm Wilson to serve out an expired term. At that time, Judges on the Court of Appeals ran for office; they were not appointed as they are today. And in 1974, I was a recent law graduate, Professor Siegel and I were just starting into private practice. I met Judge Stevens when he was campaigning to be elected to a full term on the Court. And the circumstances under which I met him were as follows: I was vice president of a bar association known as the Bedford Stuyvesant Lawyers Association. That was a black bar association in Brooklyn. And the Bedford Stuyvesant Lawyers Association, together with the regular Brooklyn Bar Association, gave an event one night. I guess it could be best described as candidates' night, and we had invited all of the candidates running for the Court of Appeals to come and speak. I really can't tell you how much it meant to us, how proud we were to feel that we were helping the election of the first black Judge to the Court of Appeals. I met Judge Stevens that night; I had a long conversation with him. He spoke to our group, our combined group, and we were very, very inspired. We were absolutely confident that when this election took place, that the Judge would be elected to a full term. Because we knew, ironically enough, that the Judge had the support of absolutely everybody as far as the eye could see. Every bar association we had ever heard of, every professional association, doctors, dentists, lawyers, citizens, it wasn't even a contest. And there were five people running for what, at the time, were two open seats. And the Judge placed third. Now if disappointment is a word, I don't think I can begin to tell you how let down we were. And as a matter of fact, this unexpected development, this defeat of Judge Stevens was, in large measure, what resulted in the change in the law, which resulted in Court of Appeals Judges being appointed rather than elected. But he was very remarkable, and I saw him after the election. And I was absolutely crushed. But he seemed to take it all in stride. He returned to the First Department, and he continued, as you know, to serve with dignity and with distinction. I, at the time, was absolutely amazed by his resiliency. As time went by, of course, I got over it. I didn't really think about it a lot for years. As a matter of fact, I didn't think about it really until very recently when I started to think and to research in Al's great book for this presentation here today. I was reminded all over again of the events of 1974, and I started to assemble more biographical material on the Judge so I could, in hopes, put this into some kind of context. I was looking for some kind of key to his remarkable strength of character and that resiliency that I just described to you. And as I read through the Judges of the Court of Appeals (1)q and grew to know more about his background, I think I got some insight into his character. I discovered that Judge Stevens was from South Carolina. And not just South Carolina, he was from what we call the out islands, or the sea islands. And he was born and he lived on John's Island. Now I didn't know that and, when I read it, I was not really surprised, because I am very familiar with that area of South Carolina. As a matter of fact, my own father and grandfather are from that same area. …


e14522 Background: With the aging population, malignancies, including hepatocellular carcinoma (HCC) in the elderly represent a significant health burden. The perception that older cancer patients may be at higher risk than younger patients of toxic effects from cancer therapy but may obtain less clinical benefit from it is mainly due to known toxic effects of cytotoxic chemotherapy. It is not known how older patients respond to targeted therapy. We aim to evaluate and compare the efficacy and tolerability of single agent sorafenib in treating elderly and younger patients with advanced HCC. Methods: We retrospectively analysed consecutive advanced HCC patients treated with sorafenib between November 2006 and December, 2009 in our centre. The patients were categorized into older (age ≥ 70 years) and younger (age < 70 years) groups. The demographic data, sorafenib-related toxicities and survival outcome were compared between these two age groups. Progression-free survival (PFS) and overall survival (OS) wer...


Poster, with yellow background, announcing National Art Week, during which "$5,000,000 worth of American art will be offered for sale at community art fairs throughout the U.S.A: Drawing, painting, prints, sculpture, photography, craftwork."


Security is more important nowadays. Because the connection of every device is available on the internet. Their attacker can easily steal our credentials and Take advantage of System and misuse our secret data Like passwords, Date of birth, Etc. Honeypot is widely used technique to lure the attacker so it can be trap, then forensic can be performed. It is clear with its name first we lure attacker to believe its live system, so they can take advantage of it. Our main aim in introducing a honeypot is to provide cost-effective security over the system there we can understand and track, and monitor hacker activity using the Canary tokens using Docker on hosting on Cloud Enterprise here AWS. Although there is no guarantee that it can completely prevent security breaches, network analysis tools can serve as valuable aids for intrusion detection and network forensics. In recent times, the research community has extensively utilized these tools to investigate various network security issues, such as Internet worms, preventing spam, countering DoS attacks, and more. By analyzing network traffic, these tools can help identify anomalous activities and patterns, enabling network administrators to take appropriate measures to safeguard their systems. Ultimately, this abstract underscore the significance of honeypages and honeytokens as part of a comprehensive security strategy in today's ever-evolving threat landscape.


The aim of the paper is to show the characteristic features of jokes about Polish highlanders and analyse them to identify the comic script of a highlander. This group of jokes is treated as a good illustration of Christie Davies's ethnic jokes theory concerning witty versus stupid and centre versus periphery oppositions, as well as mind over matter in general. A particular type of reasoning and the use of regional dialect are distinctive features of the joke targets that make it possible to perceive these jokes as a culturally specific phenomenon. The head shepherd (called baca) is the key character of the cycle. He is a very down-to-earth person, who is proud of his practical wisdom and has a very relaxed attitude to life. His lifestyle is usually contrasted with that of ceper – often a tourist – treated as a kind of intruder who asks stupid questions and does not know how to appreciate life and what really matters in it. The jokes about highlanders are analysed within the paradigm of General Theory of Verbal Humor, and particularly its reasoning and reversal Logical Mechanisms. Even though Christie Davies treated the Logical Mechanism with some scepticism, claiming it is of no use in the GTVH (Davies 2004, 2011b), he would not probably mind the logic of highlanders' utterances and behaviour being analysed. We believe he may even have enjoyed that.


In the n-jobs,1-machine case, the purpose of the stochastic scheduling problem (SSP) is to determine, at each decision time, what task currently has to be processed. Under the assumption of stationary probability transition matrices, the SSP is a markov decision problem based on the maximisation of the total expected discounted revenue for the whole production schedule over an inflnite time-horizon. The simple case of structurally independent jobs can easily be solved as a bandit problem by the dynamic allocation index rule. But when general precedence constraints are considered, some elementary tasks can be common to several difierent chains in the graph. A two-level decision structure then has to be set up: simple chains of tasks can deflne elementary processes which are connected together to constitute "superprocesses". The problem analysed in this paper is how to construct superprocesses in such a way that the current optimal schedule can still be determined by index rules.


Communal Hospital in Christiania. At two departments (VII and IX), which are conducted doctors, injections of quinine are not given for These two departments, therefore, served the comparison was the more fair as all three admitted the same class of patient under the same with the exception of the quinine treatment. The studied was from January 1st, 1920, to April this period Departments VII and IX treated pneumonia, 58 of which terminated fatally, mortality


Double property connotation of product barcodes establishes the research value on traceability of hospital management. This article investigates the uniqueness and traceability of 288 barcodes in order to understand the hospital management meaning of product barcodes in the current practice. The result shows that the uncertainty of barcodes information affects the behavior on the hospital management because of the differences among the applied standards and the absence of behavioral norms on the management. It presents specific suggestions at last.


This paper analyzes the Object Relational Mapping(ORM) component——NHibernate that use extensively currently.Aiming at the shortage of NHibernate,it puts forward improved ORM model,designs and realizes a lightweight ORM component——MYPL based on.NET platform according to this model.It makes use of the component does not need to be write any mapping document to realize data lasting operations such as object relations mapping and so on,and reduces between the service level and the data level coupling enormously,enhances the system's extendibility,maintainability and the application system development efficiency.


Localized oscillating fields are beam splitters that can entangle internal and longitudinal momentum states in an atomic beam. Differentially detuned separated oscillatory fields and an am modulator constitute a {open_quotes}white fringe{close_quotes} longitudinal interferometer which rephases velocity averaging by a process analogous to half a spin echo. Differentially detuned separated oscillatory fields are used to produce a downstream coherence or rephase an upstream coherence in an atomic beam. {copyright} {ital 1998} {ital The American Physical Society}


al. t i le r s , th i r ty f ive , g i r l s , ids a r e sil k a t t h e Woni w i t h a s t r a n g e e p id e m ic v r e s e m b l e s tons i l i ti s. a n d G r a h a m a r e in a t ! e v e r y p r e c a u t i o n is beemployed to s u p p r e s s i ts s p r e a d , ,ut so fat th e medi ca l a u t h o r i t i e s ave (teen un ab le to cope w i th it. The f ir-t d e v e l o p m e n t s w e re no te d jumlay when t w e n t y t w o y o u n g lad ies ere stricken. T h e n u m b e r o f p a  tents habeen s t e a d i l y i n c re as in g , lrs. i a ii a he r.a f t e r s h o w i n g th e 'livs , * ne r o o m s of t h i r t y . i is, w a s a lso s t r i c k Tl.o . iio w e r e f o r t u n a t e eno ugh to e ape h a v e t a k e n t h e ro le f nurse, and, o w i n g to the absence f the kitchen m a i d s , have been as isling iii e t v i n g t h e m e a l s to th atients. The disease has been d ia g n o se d a s Funicular T i c s i p h o b i a . " H o w e v e r , bv pretend lo k n o w w h a t this m e a n s , t is similar to t o n s i l i t i s and is aclompanied by fever . Se ve ra l of t h e iii' are uni te s ick, b u t none danerously -<>. T r a i n e d n u r s e s h ave een engaged a n d a r e s t a y i n g a t th e Romans Bui lding d u r i n g th e ep ide m-


Absfruct- The Nb3Sn superconductor possesses a higher critical temperature than the NbTi strand. Therefore, it is now possible to make highly stable superconducting strands. We examined the manufacturing process of AC Wb3Sn strands. The internal Sn diffusion process showed a higher critical current density than the conventional process. Nb3Sn strands for AC use have a high Jc with lowtemperature reaction heat treatment, because they have fine filaments to decrease AC loss. We made a 4OOkVA class superconducting coil using the developed Nb3Sn cable with the React & Wind method. The loss density of this coil was 25.7MW/m3 at the point just before the quench. In this case, the temperature of the cable increases about 3.3913. This means that the coil using Nb3Sn cables has a very high stability in AC use. systems. The basic strand was prepared by the internal Sn diffusion method in order to simplify the manufacturing process. Special attention was given to the following parameters; filament diameter, interfilament spacing, and the condition of the reaction heat treatment. Then, upon the result of such examination, we prepared a primary strand and fabricated an AC coil by the React & Wind method with a stranded cable. From the investigation of the electrical and thermal characteristics with transport current, the applicability of Nb3Sn cables for AC usage was clarified.


The disposition of 1-(2-chloroethyl)-3-[1 '-(S'-p-nitroben zoyl-2',3'-isopropylidene)-a,$-D-ribofuranosyl]-1 -nitrosourea (RFCNU) was investigatedin animalsfollowingi.p. administra tion (35 pmol/kg) of the drug labeled with '4Cin three different positions.The appearance and disappearancekineticsof the label in blood and plasma were strongly dependent upon the labeled species administered to animals. Protein binding of [carboxyl-'4C]- and [carbony!-14C]RFCNU greatly prolonged the bloodand plasmahalf-lifeof thesetwo labeledspecies.No intact RFCNU was found when rat plasma samples were ana lyzed using high-performance liquid chromatography, indicat ing the very short half-life of this compound. Mostof the dosewas recoveredinthe urineafteradministra tion ofthe carboxy!-'4C and ethyl-'4C species and in the expired air as '4C02after administration of the carbonyl-14C species.


This paper presents a short review of localisation in strongly interacting, high quality dilute 2D GaAs systems. At zero magnetic field, studies of the temperature dependent resistance of both 2D electron and hole systems show a transition from insulating to metallic behaviour with increasing carrier density. However, careful examination of the 2D hole systems reveal the presence of localising quantum corrections to the conductivity which persist down to the lowest measurement temperatures. Our results highlight the importance of avoiding electron/hole heating at low temperatures and argue against the existence of a 2D metallic phase at B = 0.


Typical area in Yellow River estuarine tidal flat is chosen and studied.The dynamic response process of saturated fine grain soil and the Penetration stress,peak strength,residual strength,the variation of sensitivity,and the influence of the variations of pore water pressure and the liquefied layer on the liquefied process of the silt soil in the area under cyclic loading are investigated and compared by real-time monitoring of pore pressure,static cone penetration test,vane shear test and the geotechnical test.Results show that the change of soil structure has close relations with the characteristic of energy absorption,the response of pore pressure under cyclic loading.The liquefaction of the silt soil in the area of Yellow River delta happens in hard crust mainly due to the cyclic loading.With the increase of the cyclic number,the liquefied layer extends to deep site.The changing tendency of the physical index of soil mass shows obvious difference with the change of depth due to the action of cyclic loading.


Unlike the old development process models, agile provides flexible methods adapted to requirements change. Although, agile methods such as Scrum are widely used today, an important number of agile projects end up in failure. This is due mainly to inaccurate estimates of time and lack of a structured change control process. However, tracking and controlling changes is important for a better project control. The main objective of this paper is to propose a tool for change controlling in scrum process. For this purpose, we use the COSMIC Functional Size Measurement method for a precise quantification and rapid evaluation of a change request. Reporting, tracking, and controlling the change status per project at different levels of details will certainly help in future projects management.


Aire is a master of central tolerance. Goldfarb et al. compare mice with recessive or dominant-negative Aire patient mutations to dissect the mechanisms that underlie dominance and identify an autoregulatory mechanism by which Aire negatively modulates its own expression.


Recently the rst commercial HPF subset compilers have appeared. This paper reports on our experiences with the APR XHPF compiler, version 1.2, for the Intel Paragon. At this stage, we do not expect optimum performance of our HPF programs, even though performance will eventually be of paramount importance for the acceptance of HPF. Instead, the objective is to study how to convert large F77 programs to HPF such that the compiler generates eecient parallel code. We use three case studies to identify several problems; we discuss our solutions at the program level, and present the results on the Intel Paragon. We use the dense matrix-matrix product to show that the distribution of arrays and the order of nested loops signiicantly innuence the performance of the parallel program. This innuence is of great importance, because loop parallelization and array distribution are the corner stones of HPF. We use Gaussian elimination to study the parallelization strategy of the compiler if the (optimal) parallelization is not clear from the data distribution. This provides some insights into the analysis and optimization capabilities of the compiler, and shows how much eeort is required from the programmer to get an eecient parallel implementation. Finally, we use a small application to show that the interprocedural analysis introduces problems for the parallelization, even though all subroutines of the application are easy to parallelize by themselves. The application consists of a nite volume discretization on a structured grid and a nested iterative solver. The problems arise when arrays with alignment attributes or with distribution attributes are passed to several subroutines, in which alignment and distribution of the dummy arguments are declared, and when in addition such subroutines are called at several places in the program with diierent arguments.


This paper addresses, in an analytical and descriptive way, two philosophy teaching methodologies for high school education based on an analysis of Immanuel Kant's ethics. In the first place, the study has a qualitative character and from the bibliographic and documentary research attempts to propose practical teaching techniques. From a high school student point of view about the socio educational scenario related to the Philosophy subject, it conducts a retrospective of the recent legal reforms in the new curriculum of Brazilian basic education. After enunciations of a serpentine legislation and of a contempt culture, the kantian ethics and its high schooler's comprehension are explored. According to the guidelines of the Brazilian National Core Curriculum, the concept of morality for Immanuel Kant works as a context for the development of two teaching methodologies to be applied in the secondary education. This work aims, therefore, to show the possibility of teaching complex philosophical themes through an accessible language to the youth. This paper concludes reflecting upon the necessity of an educational activism from the academic community in order to defend the independent thinking of Brazilian students.


Due to the deficiencies in cost accounting means,the techniques of sensitivity analysis have never been applied to the medical domain yet.With the full-cost accounting means being improved and popularized,a basis of the application for sensitivity analysis has been reached in the business indicators of clinical divisions。 Through the introduction the techniques of sensitivity analysis and the leading of more rational management of clinical divisions,the economic and social benefits of the clinical divisions have been raised,and effectiveness of the hospital management have been achieved continuously.


The object of research is the financial security of joint-stock companies in Ukraine. The problematic aspect in ensuring financial security of business entities is the identification of relevant factors that can cause a negative result of their financial and economic activities. In the course of the research, a critical analysis of the approaches of Ukrainian and foreign scientists to the allocation of macroeconomic threats to the financial security of joint-stock companies, as well as the current legislation, is conducted. The result is the division of all factors in accordance with regulatory legal acts into four sources, namely: investment factors; macroeconomic development factors; fiscal factors; other factors. Such classification of sources, unlike existing ones, takes into account specific aspects of financial activity of corporate structures. It is also proved that threats of a macroeconomic and microeconomic nature can create both conditions where there is a stabilization character and act as a determinant of the financial security of joint-stock companies. Based on the obtained results, the company provides an opportunity to quickly respond to the place of occurrence of a threat to its financial security and apply adequate tools to prevent or minimize the consequences of such threats.


Image denoising has become a very essential exercise all through the diagnosis especially in case of medical image processing involving ultrasound. Speckle pattern is one of the most complicated multiplicative noise which hardly degrades visual quality of clinical ultrasound images. Real time ultrasound images posses inherited speckle pattern which reduces its resolution and contrast there by degrading the diagnostic accuracy of the ultrasound image. The presence of speckle noise in fetal ultrasound images make the conditions worse to carry out prenatal diagnosis of congenital heart disease. This is due to the impact of edge and local fine details that are not very clear for diagnosis. There exists an ever growing research demand for contriving a robust speckle reduction filter to enhance the quality of the speckle affected image and to preserve the essential features. This paper describes about the proposed despeckling filter contrived with the concept of Particle Swarm Optimization of weight parameters to improve the algorithm of Quadrilateral Rayleigh Maximum Likelihood Estimator to suppress the speckle noise in clinical ultrasound images. The proposed filter establishes the Rayleigh Maximum Likelihood Estimator and particle swarm optimization technique hence called as PSO based QRML filter. The experimental result shown in this paper proves the efficacy of the proposed filter in comparison with several existing despeckling filters in terms several performance indices and image profile. Experimental results shows that the proposed filter removes the speckle noise effectively and thus outshine the conventional filters.


Chagas disease is an endemic illness in Latin America caused by the parasite Trypanosoma cruzi. Current chemotherapies are old and inadequate, and the emergence of drug‐resistant strains underscores the need of new drugs. Platinum‐based complexes have been shown to be a promising approach against parasitic diseases. In this work, the effect of 1,1′‐bis(diphenylphosphino)ferrocene pyridine‐2‐thiolate‐1‐oxide Pt(II) hexafluorophosphate, Pt‐dppf‐mpo, was studied on T. cruzi. A promising antitrypanosomal activity was determined for the CL Brener strain with a low cytotoxicity determined using in vitro‐cultured mammal cells. The compound uptake in parasites treated with concentrations of 1× and 10× the IC50 value reached ~75% and 19%, respectively. Pt‐dppf‐mpo induced necrosis after 24 hr of parasite incubation. This event was preceded by depolarization of mitochondrial membrane potential. Cell vitality assays showed high esterase activity in treated parasites. However, despite this increase in metabolic activity, treated epimastigotes showed rounded morphology and loss of flagellum with a reduction in mobility as compound concentration and/or time of incubation was increased. At last, we demonstrate that Pt‐dppf‐mpo incubation also affects the trypomastigote infection process as well as the infection persistence evaluated as the number of amastigotes per cell in a dose‐dependent manner.


Mutations in genes encoding isocitrate dehydrogenase (IDH) 1 and 2 are frequently observed in numerous cancers including acute myeloid leukemia (AML), myelodysplastic syndrome (MDS) and angioimmunoblastic t-cell lymphoma (AITL). The roles of mutant IDHs in tumorigenesis remain unclear because of a lack of appropriate cancer models. Here we established a mouse AML model harboring an IDH2 mutation. IDH1/2 mutations in AML frequently occur simultaneously with mutations in other genes such as NPM, DNMT3A , and FLT3 . In accordance with these observations, IDH2/R140Q, NPMc, DNMT3A/R882H and FLT3/ITD cooperatively induced AML in the mouse model. When only three out of the four mutant genes were transduced, the onset of AML was delayed in any combinations. These results clearly indicate that all four mutations are necessary for the efficient induction of AML. Gene-expression analysis indicated that IDH2/R140Q and NPMc cooperatively activate Hoxa9/Meis1 and hypoxia pathways to maintain AML cells in vivo . These two pathways are likely to be important for the IDH2/R140Q-mediated engraftment/survival of NPMc+ cells in mice. DNMT3A/R882H further upregulated the expression levels of Meis1. Furthermore, DNMT3A/R882H promoted the maintenance of cells in an undifferentiated state. Previous studies have shown that FLT3/ITD promotes cell growth and survival. Taken together, our results suggest that multiple signaling pathways are activated in this IDH-mediated AML system.

The tumor-associated mutant IDHs catalyze the formation of an oncometabolite 2-hydroxyglutarate (2-HG), which dysregulates a set of α-ketoglutarate-dependent dioxygenases that includes epigenetic regulators (TETs and KDM4A), hypoxic signaling molecule (EGLN) and others (collagen prolyl 4-hydroxylases). Because mutant IDHs act via a mechanism that is completely different from those of previously described oncogenes, it has attracted increasing attention as a new therapeutic target. Small molecules that potently and selectively inhibit the mutant IDHs induced differentiation of cancer cells in vitro . However, it remains unclear whether the mutant IDHs are valid targets for cancer therapy in vivo . Here we report that AML harboring IDH2/R140Q can be blocked by conditional deletion of IDH2/R140Q, even after leukemia has developed. Deletion of IDH2/R140Q blocked 2-HG production and the maintenance of Csf-1r+ and c-Kit+ leukemia stem cells, resulting in survival of the AML mice. These results indicate that the IDH2 mutation is critical for the development and maintenance of AML stem cells, and that mutant IDHs are promising targets for anticancer therapy.

Disclosures: No relevant conflicts of interest to declare.


Although marketing is considered a very important aspect of agricultural production, it has been a neglected aspect of agricultural development plans and this has led to a situation where marketers of fresh tomatoes are not able to track their level of profitability and which invariably makes it difficult to attract prospective investor to the business. This study examines empirically profitability and operational efficiencies of fresh tomato marketing in South Western Nigeria. The study employed primary data using structured questionnaires to collect information from 100 randomly selected fresh tomato marketers in the study area. Data collected were analyzed using descriptive statistics; gross margin and marketing efficiency analytical techniques. The result of the analysis revealed that for every ₦100 invested in fresh tomato trading in the study area, wholesalers, retailers and wholesalers/retailerrealized profit of ₦28.00, ₦18.00 and ₦ 258.00 respectively while the average operational efficiencies of wholesalers, retailers and wholesalers/retailer are 60.85%, 74.00% and 80.50% respectively. These positive and size of profits obtained for each fresh tomato marketing institutions is an indication that these institutions were able to recover their operating expenses; hence, marketing fresh tomato in the study area isprofitable and efficient.


An unusual combination of idiopathic superior and inferior vena caval obstruction occurred in a 15-yearold boy. Portal hypertension with ascites and associated bleeding esophageal varices developed as a result of hepatic outflow obstruction due to the occluded inferior vena cava. Surgical decompression of the portal venous system was accomplished by splenectomy and placement of a Teflon tube graft between the splenic vein and the divided pulmonary artery to the left lower lobe, since the standard methods of creating an Eck fistula were not possible in this patient. The patient has experienced marked clinical improvement during the nine months following operation.


In nature, fish have the ability to form flow-based maps to assist localizing predator or prey using the lateral-line system. Yet it is not fully understood what techniques are used by fish to draw these flow maps. Biologists try to figure out fish techniques by investigating different hypotheses [1]. Inspired by the lateral line of fish, we propose in this paper model based array signal processing techniques used to visualize the air-flow maps. The results show an ability to visualize the flow field generated by a dipole source using lateral-line system.


High-dose chemotherapy (HDCT) with autologous hematopoietic support in metastatic germ cell tumours (GCTs) has been investigated for over 25 years. Initial phase I/II studies achieved durable remissions with HDCT for a small subset of heavily pre-treated platinum-refractory patients with relapsed disease.1–3 Survival for metastatic GCTs has dramatically improved from 5% in the early 1970s to about 80% today.4,5 This improvement has been largely attributed to the advent of cisplatin-based chemotherapy and modern surgical techniques. The outcome for the 20% to 30% of metastatic GCTs whose disease relapses following cisplatin-based chemotherapy is much less favourable. Options for salvage therapy include conventional dose cisplatin-based chemotherapy (CDCT), with paclitaxel-ifosfamide-cisplatin (TIP)6 or etoposide-ifosfamide-cisplatin (VIP)7 or HDCT with autologous stem cell transplantation (ASCT). As initial therapy for patients with poor risk chemosensitive metastatic disease, upfront HDCT compared with CDCT has demonstrated no survival advantage in randomized trials.8–10 Whether HDCT is superior to CDCT as first-line salvage therapy for patients with relapsed disease is controversial. The only randomized trial conducted in this setting (European Group for Blood and Marrow Transplantation [EBMT]-IT-94) failed to showed superiority for three cycles of CDCT with VIP or vinblastine-ifosfamide-cisplatin (VeIP) followed by HDCT compared with four cycles of CDCT.11 However, there were methodological limitations to this study, such as the inclusion of cyclophosphamide, a drug with minimal activity in GCT, in the high-dose chemotherapy regimen and a lack of standardization for surgical and systemic treatment following progression.

Recently, the International Prognostic Factor Study Group (IPFSG) retrospectively reviewed data from 1984 patients with relapsed GCT previously treated with cisplatin-based combination chemotherapy.12 A five-category prognostic factor model was developed that reflected large differences in outcome, with progression-free survival (PFS) and overall survival (OS) at 2 years ranging from more than 70% in the most favourable group to less than 10% in the highest risk group. A subsequent retrospective analysis from the same group showed an improvement in PFS and OS in each prognostic group (with the exception of OS in the low-risk group) for upfront HDCT versus CDCT.13 In this issue of CUAJ, Beausoleil and colleagues provide a single institution retrospective analysis from the London Health Sciences Centre of 38 patients with relapsed GCT treated with first-line salvage chemotherapy with either four cycles of VIP/VeIP as CDCT or three cycles of VIP/VeIP followed by a single cycle carboplatin-based HDCT over a 20-year period.14 The authors' conclude that the IPFSG prognostic factor model performed similarly in their institutional dataset and that CDCT plus HDCT was superior to CDCT alone (2-year PFS 78% vs. 22%; 5-year OS 72% vs. 19%). This study demonstrates that IPFSG model is applicable to a Canadian context and provides additional support for the use of HDCT as first-line therapy for appropriately selected patients with relapsed metastatic GCT.14

Retrospective comparisons of HDCT versus CDCT alone as first-line therapy for relapsed GCT are limited by several considerations: physicians may identify healthier patients who are able to tolerate HDCT compared with CDCT alone; the CDCT comparator group includes patients who were planned to receive HDCT after initial tumour debulking with CDCT, but never received HDCT because of toxicity or an inadequate therapeutic response; and the observed differences may be due to improvements in supportive care and surgical techniques for resection of residual masses that coincide with a greater proportion of patients receiving upfront HDCT compared with CDCT alone over time. An international randomized trial (TIGER) plans to randomize 390 patients to four cycles of CDCT with TIP compared with two cycles of paclitaxel-ifosfamide followed by three cycles of high-dose carboplatin and etoposide with autologous stem cell support (TI-CE).15 Whether this study will complete its planned accrual to definitely address this important question is unknown, as studies in metastatic GCTs have been increasingly difficult to conduct, due to the relative rarity of the patient population,16 the challenges of securing support for an international academic trial without a pharmaceutical sponsor, and the practice patterns of many institutions who have adopted HDCT as a first-line strategy based upon the existing non-randomized data.

Notwithstanding this lack of level I evidence in support of upfront HDCT for relapsed disease, there are many unanswered questions in the management of relapsed GCTs that may be addressed by non-randomized data analyses. These unanswered questions include: the optimal number of cycles of HDCT (one, two and three cycles have been used by different groups) with autologous stem cell support; if relapsing patients should proceed directly to HDCT upon diagnosis of relapse or if they should initially be treated with one to three cycles of induction CDCT to stabilize their disease and allow time to coordinate HDCT with autologous stem cell support with the transplant team; and if there are certain groups of patients with relapsed disease, such as patients with primary mediastinal non-seminoma or late (>2 years) relapse that cannot be resected surgically, whose outcome is so poor that they should not be considered candidates for HDCT. What is clear, however, is that GCTs are unique as a metastatic solid malignancy that can be cured following relapse with additional chemotherapy. This medical imperative demands that all patients with relapsed GCT be managed in centres with specialized expertise.17–19


In this work, a direct image reconstruction algorithm for PET is proposed. This method follows naturally from the concept of LOR, and easily admits depth of interaction and time of flight information. In addition, this algorithm does not require the computation of sinograms or a system matrix. Thus, it is not restricted in the formation of high pixel density images and allows the image formation in real-time (simultaneously to the data acquisition process). One of the key advantages of this algorithm is the preservation of high frequencies, producing accurate images that can be generated in high resolution, because of the lack of space restrictions imposed by the intermediate generation of sinograms, aside of the native support of real-time image reconstruction. In this work, a C++ implementation of the described algorithm has been developed. Image reconstructions of simulated PET events according to the MindView (a brain dedicated PET insert) scanner geometry and real data measured with the first one ring prototype system have been performed. Results show capability of correct image formation, either with simulated and real data.


With the 2004 European Parliament elections approaching, it is useful to consider what affects voting in these elections. This paper addresses the puzzle of declining turnout in European Parliament elections. After reviewing the influential "second order elections" explanation emphasizing domestic influences on turnout, especially Mark Franklin's recent study stressing the importance of electoral salience factors, we develop a revised model to incorporate EU as well as domestic variables. Our model indicates that EU influences, at least on the aggregate level, may have more influence on EP elections than previously reported. Tests of our model for the first five EP elections, 1979 through 1999, find that it provides an alternative explanation of turnout similar in power to Franklin's model. Because of changes in membership of the EU, our alternative model may be preferable for explaining future turnout variation in EU elections.


The ultrafast photocurrents in a typical 3D topological insulator (TI) Sb2Te3 were probed with THz emission spectroscopy by tuning the polarization of excitation pulses and the sample's azimuthal angle. The different ultrafast photocurrents driven by the linear photogalvanic effect, circular photogalvanic effect, and thermoelectric effect were distinguished from THz emission signal. Results potentially provide insights into the ultrafast all optical modulation of THz emission with non-external bias field, which could play a vital role in future TI-based high-speed THz optoelectronic and optospintronic devices.


ABSTRACT: Intra-abdominal hypertension (IAH) is the persistent increase of intra-abdominal pressure (IAP) that could be caused by several pathologies. It is capable of promoting organ dysfunction, thereby increasing the mortality rate of human patients. As for cats and dogs, there are still few reports on how this pressure can be monitored and treated as a routine for admitted and hospitalized animals and on its relationship with the mortality of the patients. Therefore, the objective of this paper was to report a case of IAH secondary to chronic diaphragmatic rupture in a dog, which was treated with a temporary abdominal closure (TAC). A bitch was admitted to the veterinary hospital to undergo an elective ovariohysterectomy when it was diagnosed with a diaphragmatic rupture and displacement of the liver and intestinal loops in the chest. After repositioning these structures in the abdominal cavity, tension was observed in the abdomen. A temporary abdominal closure was then performed with a Bogota bag. Immediately after the surgery, the IAP was measured, presenting a value of 15 mmHg, indicating that there was an increase in intra-abdominal pressure. The animal was hospitalized, and IAP was monitored. After 24 hours, IAP was 5.8 mmHg when the Bogota bag was removed, and definitive celiorraphy was performed. The patient showed satisfactory clinical progress and was discharged 72 hours after the surgical procedure. The treatment used for IAH proved to be effective and contributed to the quick and satisfactory recovery of the patient.


Background: Human toxocariosis is a parasitic zoonosis caused by larval forms of the genus Toxocara. The eggs hatch after being ingested, penetrate the intestinal wall and migrate via the blood stream through to the liver, hence spread to other organs. Erratic larval migration by the different soft tissues in humans, generates four syndromes, Visceral Larva Migrans, Ocular Larva Migrans, neurotoxocariosis and covert toxocariosis. A seroprevalence study of Toxocara canis among students from Veterinary Medicine and Graphic Design in Mexico City was conducted, as the Veterinary student has regular contact with animals was compared with students who have no contact with animals in their study program. Materials, Methods Results: In both groups of students blood samples were collected and centrifuged to obtain the serum was evaluated by Toxocara serology ELISA (enzyme-linked immunosorbent assay). All participants completed a questionnaire supplying personal data and specifics regarding dog ownership and hygiene practices. Serology data and results from the questionnaire were analyzed using the Fisher´s exact test, Chi-square and odds ratio (OR) test. The frequency of Toxocara infection tended to be greater (P = 0.11) in veterinary students than in those from graphic design (13 % and 7.0 % respectively). Some of the risk factors that were considered were: do not wash your hands after eating, frequent contact with dogs, has dog at home, eating on the street and dewormed your dog, neither factor was associated nor were risk factors for Toxocara antibodies present. Discussion: The fact that almost twice as many veterinary students were seropositive indicates a higher risk of Toxocara canis infection in those individuals, which may be due to veterinary students having greater contact with sources of infection (animals, feces, soil, hair, and farms), regardless of the ownership of dogs. In a study in Canada researchers found no differences among veterinarians and other professionals in anti-Toxocara antibodies, finding similar values (8.8% and 9.6% respectively) in both, and also found no association between dog ownership and anti-Toxocara antibodies a study in Austria found that veterinarians were the second occupational groups that had more antibodies (27%) compared to the control group (2%) and the main source of infection was identified as cats and dogs. Many studies have shown that risk factors are very important in the epidemiology of toxocariosis, primarily the presence of dogs and cats living together with people. It has been reported higher infection in individuals who were in contact with dogs. In several cities of Mexico, highest percentages of dogs infested with Toxocara were reported, with a mean of 35.5% and a range from 19.0 to 63.36%. It has been reported up to 100% of stray puppies can be contaminated with Toxocara in samples collected from dorsal and perianal hair which constitutes a great potential of infection considered that 94% of the Toxocara eggs were embrionated. Other studies show less contamination of hair with eggs of T. canis (40.9%) but still shows the importance as a potential source of infection for humans. Eating in the street or poor hygiene before eating were not factors related to the disease. Although no association was found with the lack hand washing and Toxocara, other researchers have identified this problem as a risk factor associated with Toxocara. It can be assumed that depending on the degree of contamination by Toxocara exposed to each individual, the hygiene practices may have different impact on the presence of the parasite. The results indicate that veterinary students are more prone to infection with Toxocara.


Corrosion of steel rebars and susceptibility of reinforcement steel to chloride ion attacks are the two major problems for the construction industries and thereby a huge amount of money is spent to repair it. Epoxy coating on the steel rebars can be one cost-effective solution to alleviate the detrimental effects of corrosion in concrete structures. In the present research, plain and epoxy coated rebar (ECR) samples were chosen to study the correlation between microstructure, hardness and corrosion performance. The microstructures of the investigated thermomechanically treated (TMT) rebars primarily reveal tempered martensitic rings at the outer surface followed by a narrow bainitic transition zone in between along with a ferrite-pearlite microstructure at the inner core. The corrosion resistance of plain and epoxy-coated rebars in naturally aerated 3.5% NaCl and 1% HCl solutions were studied using gravimetric test, open circuit potential (OCP) test, and linear polarization monitoring techniques. It has been witnessed that the corrosion current (icorr) has been shifted towards lower values and polarization resistance (Rp) values are higher for ECR samples which is a clear indication of higher corrosion resistance of the ECRs than the plain rebars. Energy dispersive spectroscopy (EDS) analysis reveals the presence of iron hydroxides and iron oxides. However, x-Ray diffraction (XRD) analysis indicates the existence of various types of oxides, hydroxides, and oxy-hydroxides like iron chloride hydroxide [Fe2(OH)3Cl], goethite (α-FeO(OH)), lepidocrocite (γ-FeO(OH)), magnetite (Fe3O4) and bernalite [Fe(OH)3(H2O)0.25] in the epoxy coated rebar samples whereas, plain rebars indicate the presence of goethite (α-FeO(OH)), maghemite (γ-Fe2O3), magnetite (Fe3O4), hydrogoethite (Fe2O3.H2O), lepidocrocite (γ-FeO(OH)) and iron oxide (Fe21.34O32). All the experimental results confirm that ECR samples are more corrosion resistant under both acidic and saline environments.


It was in 1928 that the Yin Ruins (Yinxu) began to be excavated scientifically. During the past 70-odd years archaeologists have carried out some one hundred scientific excavations in various areas of Yinxu. They have revealed the then palace and ancestral temple, royal mausoleum, handicraft workshop and kin graveyard quarters. These vestiges include the palace and ancestral temple area centered on Xiaotun, the royal mausoleum and sacrificial area centered on Xibeigang, the bronze foundry-sites represented by Locus North of Miaopu and Locus West of Xiaomintun, the bone artifact workshops represented by Beixinzhuang and Renjiazhuang, the jade-working places represented by Xiaotun, and the oracle shell and bone stores represented by Locus South of Xiaotun and Locus East of Huayuanzhuang. Within the Yin Ruins that occupy about 30km, archaeologists have excavated more than ten thousands of contemporaneous tombs and brought to light quantities of objects, such as bronzes, inscribed oracle shells and bones, jades, bone artifacts and pottery vessels of royal and the common people's use. The discovered vestiges and objects provided direct evidence for studying the social organization and structure, the form of living and technology of production in the Yinxu period. Xiaomintun is located on the border of the Yin Ruins, and, along with its vicinity, has a good foundation of archaeological work. In the 1950s, the Anyang Archaeological Team, IA, CASS carried out archaeological excavation to the west and north of the village, and discovered weapon molds and other remains related to bronze foundry to the west. In 1969 to 1977, they excavated above 900 Shang tombs and five horse-and-chariot burial pits and over 200 tombs of the Warring States period and after to the south of the village, i.e. in the socalled famous "burial ground of western Yinxu." In 2000, they brought to light molds for casting ritual bronzes and fragments of melting furnaces about 300 m southeast of Xiaomintun Village. In April 2003, according to the idea of the State Administration of Cultural Heritage, with the coordination of the Henan Provincial Bureau of Cultural Relics, the Institute of Archaeology, CASS and the Henan Provincial Institute of Cultural Relics and Archaeology organized jointly our Yinxu Xiaomintun Archaeological Team to carried out archaeological excavation on the Xiaomintun site. We divided the excavation area into the northern and southern areas. The drilling data show that in the northern area, in addition to modern tombs, there is a large spot of ancient cultural remains, which spreads also in the middle part. The recorded vestiges include tombs, ash-pits, cellars and rammed-earth building-foundations. In the southern area, the northern part is main a burial ground, while the southern part is a district of densely distributed tombs, house-foundations, ash-pits and cellars, and pottery molds and other objects concerned with bronze foundry were collected from the ground at many localities. Based on the results of previous archaeological excavations in the Xiaomintun area, as well as those of a preliminary drilling and the first resurvey, the academic


Research findings the influence of food consumption in postpartum breastfeeding mother to the production. Prospective Cohort Study design approach used with samples were the postpartum mothers who Gave birth as much as 40 persons. The use of data collected to observe your food recall form the food consumed by the mother for 3 days and gives Breastfeeding product observation sheets. A Results of the study Showed that there was an influence of food consumptions of post partum mother to the Breastfeeding production (fluid intake, calories total, sauropus androgynus and musa paradisiaca) and fluid intake was the predominant factor that influent to the Breastfeeding production of postpartum mother. Expected to the postpartum mother to consume the fluids as much as 8 to 12 glasses a day for breastfeeding increasing production and need to be associated with postpartum mother to consume sufficient amount of calories, sauropus androgynus and musa paradisiaca.


A dynamic vision sensor (DVS), also known as event camera or neuromorphic camera, is an imaging sensor that responds to local changes in irradiance (brightness). In a DVS, each pixel operates independently and asynchronously by storing a reference level of irradiance and continuously comparing it to the current level of irradiance. If the difference in irradiance on a pixel exceeds a given threshold, that pixel resets its reference level and generates an event (Fig. 1). The output of a DVS is therefore a stream of events, where each event is characterized by the coordinates of the pixel that generated the event, the time when it was generated and its polarity (positive if the irradiance was increasing, negative otherwise). The main advantages of this type of sensor is its high dynamic range (up to 120 dB) and its high temporal resolution (each pixel can fire an event every microsecond). However, these advantages can only be exploited if a video (series of images) can be recovered from a stream of events.


As is known, even relatively weak ground‐level perturbations (earthquakes, tsunami, explosions) may cause very significant displacements in upper atmospheric layers where the gas density is small. It results in shock formation and subsequent rapid dissipation of wave energy. This presentation deals with the upward propagation of a short, finite‐amplitude wave in atmosphere with exponentially decreasing density, including areas where the magnetic pressure prevails, and the acoustic energy is transformed to that of fast and/or slow magnetic sound. The height of shock formation is determined, and the wave attenuation due to shocks is described. Propagation from a localized source is also discussed. Some estimates are given.


Objective To investigate kidney damage caused by acute pancreatitis,so as to arouse clinically attention.Methods 42 cases of acute pancreatitis do clinical analysis.Results The acute pancreatitis with kidney damage has 24 cases,accounting for 57.15%.The kidney lesion commonly occurred in the pathogenesis course of acute pancreatitis within 72 h.The ratio of mionectic blood,infection,jaundice,using breathing machine in the patients with kidney lesion is higher than that of in the patients without kidney lesion.Conclusion Acute pancreatitis is easily develope to kidney damage,clinician should strengthen awareness of kidney disease,diagnose early,reduce the mortality.


One of the most authoritative lay articles ever published about chess ratings is a 43-page survey, modestly titled, "Chess Rating Systems," written for the third, and final, issue of the American Chess Journal. The year was 1995. The writer was a young, 30-year-old Mark Glickman, only two years removed from his graduate school days at Harvard, but already a ten-year veteran and chairman of the USCF Ratings Committee—a position he retains to this day.