A general model of cable dynamics is used to analyze the vibration of transmission lines equipped with the control device – detuning pendulums. The model considers complex loading, including nonlinear aerodynamic force and concentrated load. An early developed perturbation method, called direct perturbation method (DPM), is applied to study cable motion. This approach does not need to transform the original partial differential equation to an ordinary differential equation, and the solution procedure is systematic. Steady-state solutions and stability conditions are briefly discussed.


Abstract Struggles over social reproduction intensified and took on new forms in Japan during the interwar period, as the state found it increasingly difficult to secure the foundations for the continued accumulation of capital. Landlord-tenant disputes that erupted nationwide in the midst of Japan's post-World War I agricultural recession was one concrete manifestation of these struggles. While the significance of tenant disputes has been analyzed in great detail by scholars, there has been a surprising lack of historical scholarship on the role that female tenant farmers played within them. This absence is a manifestation of two tendencies: First, gendered assumptions surrounding the figure of the tenant farmer have led scholars of agrarian social movements to work from a relatively limited understanding of what constitutes struggle and by extension, who its protagonists have been. Second, the conflation of waged work as productive work and by extension, non-waged work as unproductive has unwittingly relegated many forms of struggle that working women participated in to the realm of the pre-political. This paper contends that far from being mere supporters – the wife corps – of what was ultimately a male-driven movement, female participants in tenant disputes produced their own powerful critiques of the way that the Japanese state and capital undervalued their lives and labor. As such, they should be understood as one link in a rich history of proletarian feminist struggle both within and outside of the Japanese empire.


Preview file:////afs/ltu.se/staff/all/andbra/Desktop/ESCD%202010%20Hockey%20LTU%20(original%20abstract%201447252).htm[2011-10-10 12:56:36] CONTACT ALLERGY IN ICE HOCKEY PLAYERS IN SWEDEN T. B. J. Eriksson*1, M. Isaksson1, M. Engfeldt2, Y. Tegner3, M. Bruze1 1Occupational and Environmental Dermatology, 2MSc.Occupational and Environmental Dermatology, Univ.of Malmo-Lund, Malmo, 3Inst.of Health Care, Dept.of Medical Sciences Univ.of Technology, Lulea, Sweden Background: Contact dermatitis and contact allergy among ice hockey players have been scarcely studied. Fibreglass, dyes from gloves and other factors have been suggested as the causatives to skin problems in this group. In order to more fully evaluate this issue we started a national investigation among Swedish elite ice hockey players including questionnaires, clinical examination, patch testing and intervention. 26 teams and more than 500 players participated Objectives: To find out the frequency of contact allergy to patch tested substances in the 6 teams which were selected for testing among the 26 teams Methods: Patch testing was performed under field conditions at the actual facility where the different teams played ice hockey. The IQ Chamber technique (Chemotechnique Diagnostics, Vellinge, Sweden) was used. 98 players were patch tested to a modified Malmo baseline series and a hockey working series, the latter containing substances representing the exposure the players had from tapes, bandages, liniments, and protective gear. In total 60 preparations were tested. The test application time was 48 hours and an experienced dermatologist made a reading of all tests after 72 hours. After another 72-120 hours a photograph was taken of the test area to enable a distant late test reading Results: Contact allergy was found in 23% of the ice hockey players. The most common groups of sensitizers were emulsifiers and surfactants (lanolin, cocamidopropyl betain, lauryl glucoside), perfumes, metals (nickel, chromate, aluminium), preservatives (thimerosal, formaldehyde, methyldibromo glutaronitrile) followed by work materials and rubber components. Conclusion: Perfumes such as oxidized limonene and substances related to liquid soaps and antiperspirants such as surfactants and preservatives were the most common contact sensitizers in the tested ice hockey players. The figures found in this study are higher than in our patch tested dermatitis population. This can probably be explained by frequent use of scented hygiene products when taking showers, men ́s perfume and perhaps remnants of soaps on wet skin facilitating sensitization in these conditions  Disclosure of Interest: none declared


Objective. To study several medications and their combinations in non-threatened hypertension worsening captopril, and moxonidine, captopril + nifedipine, captopril + moxonidine. Design and methods. We include326 patients (253 females) aged 45–89 years who referred for the urgent health care due to the non-threatene hypertension worsening. Mean duration of hypertension was 20,6 ± 0,6 years. Special questionnaires were fille in, heart rate, blood pressure by Korotkoff method, and electrocardiogram were registered. Results. Moxonidinwas shown to be more effective in patients with the sympathetic hyperactivity, captopril — in patients withouincreased sympathetic activity. The combination of captopril and nifedipine was associated with the reductioof therapy effi  ciency, and the combination of moxonidine and nifedipine — with its increase. Moreover, administration of captopril and nifedipine led to the higher rate of side effects, compared to the combination moxonidine and nifedipin.


Aim To elucidate the intracellular signaling pathways for β-very low density lipoprotein (VLDL) -induced VLDLR transcription and their effects on lipid accumulation in macrophages. Methods Phosphorylated extracelcular signal regucated kinase (ERK1/2) protein was detected with Western blot. mRNA level of VLDL receptor was assayed by RT-PCR.
Results We found that β-VLDL induced an increase in ERK1/2 activity in a protein kinase C (PKC)-dependent manner in murine RAW264.7 macrophages. Studies using different protein kinases inhibitors or activators showed that the effect of β-VLDL induced VLDL receptor transcription, which was monitored by RT-PCR analysis of VLDL receptor mRNA, was not affected by the inhibitor of P38 kinase and cAMP analog, but extremely abolished by pretreating cells with an inhibitor of ERK and an inhibitor of PKC. Studies on effects of PD98059 (the inhibitor of ERK) on β-VLDL-induced cellular lipid accumulation, which was assessed by cholesterol and triglycerid assay kit showed that ERK inhibitor decreased cellular cholestorol and triglycerid increase exposed to β-VLDL in a dose-dependent manner. Conclusions These results demonstrated that the PKC-ERK1/2 cascade was the essential signaling pathway by which β-VLDL activated VLDL receptor mRNA expression and inhibition of the ERK1/2 signaling cascade resulted in suppression of the cellular lipid accumulation induced by β-VLDL in macrophages.


Deep neural networks provide excellent performance in pattern recognition, audio classification, and image recognition. It is important that they accurately recognize input data, particularly when they are used in autonomous vehicles or for medical services. In this study, we propose a data correction method for increasing the accuracy of an unknown classifier by modifying the input data without changing the classifier. This method modifies the input data slightly so that the unknown classifier will correctly recognize the input data. It is an ensemble method that has the characteristic of transferability to an unknown classifier by generating corrected data that are correctly recognized by several classifiers that are known in advance. We tested our method using MNIST and CIFAR-10 as experimental data. The experimental results exhibit that the accuracy of the unknown classifier is a 100% correct recognition rate owing to the data correction generated by the proposed method, which minimizes data distortion to maintain the data's recognizability by humans.


This text is in the form of a "policy paper" and it examines and, initially, deals
with three preUminary questions: the first one. "Is there a 'post-Fordistic' State?";
the second one: "Is there a new global paradigm?"; the third one: "Is there a
Brazilian post-Fordism?". Then it highlights "the lessons coming from the world",
summarizing the fundamental problems and the certainties on which we count.
After examining these points, the author deals with the old, "non-Fordistic" paradigm
in Brazil, carefully discriminating the mode of regulation by "developmentism",
presently in check. That leads him to define the "crisis and exhaustion of the
old paradigm" and, finally, to a crucial point: "Reform of the Brazilian State", with
which he doses his notes.


The author describes the sculptures she has made during the past 20 years from plaster, metal, etc. Her first aim has been to provide objects with minimal visible support so that they give viewers the feeling that they are of very light weight. Her second aim has been to provide rearrangeable groupings of independent units that convey a sense of community relationship between the units. Some of the groupings have units only a few centimeters in height, others as tall as 1.5 meters. She started making these groupings about four years before moving in 1969 to southern Italy, where she and Arno Mondello launched a small community for artists, artisans, writers and agriculturalists. She presents a brief discussion of the materials and techniques she employs and of examples of her sculptures and concludes by reviewing the aims of the community and some of the organizational problems encountered.


Microfinance is defined as "Any project or component that supports delivery of very small, uncollateralized or less than normally collateralized loans; other financial services such as savings or insurance for low income clients"- (Consultative Group to Assist the Poor (CGAP)).


Summary The Kauring Gravity Gradiometry Test site offers a unique opportunity to understand the information content of various types of gravity gradient measurements and the required processing and interpretation techniques. In this paper, we utilize the measured ground vertical gravity data to simulate realistic airborne gravity gradiometry data from several current and future systems using an equivalent-source technique. We then invert these simulated data for the underlying density contrast and evaluate the performance of these inversions. The study demonstrates the effectiveness of equivalent-source based method for data conversion in the presence of scattered observations. The major density features recovered from the optimally converted gradient data are highly consistent with those from the original ground gravity.


In 2011, more than 3% of all black men in the United States were imprisoned, compared to only 0.5% of all white men. Among prisoners ages 18 to 24, black men were imprisoned at a rate more than seven times that of white men (Carson and Sabol 2012). It is becoming increasingly urgent for researchers to understand what accounts for these race-based disparities. While a broad constellation of social problems exist that likely contribute to these disparities in concert, different fields of social science tend to focus on different types of explanations. Political scientists and sociologists have tended to emphasize the role of institutional factors, including criminal justice policies and practices, in maintaining race-based disparities. Social psychologists, in contrast, have tended to emphasize individual factors, including punitive responses to crime by jurors, judges, and criminal justice professionals.


The private security industry in Latin America has been associated with human rights abuses, particularly in the context of extractive operations. Most private security guards in the region are poorly trained and do not undergo adequate vetting. These factors combined with serious deficiencies in the rule of law across the region too often enable private security companies to effectively operate outside state control and engage in human rights abusive practices. This article argues that adoption of the International Code of Conduct for Private Security Providers (ICoC) by Latin American private security companies and states, coupled with civil society engagement with ICoC's Association, may help reduce negative human rights impacts arising out of private security services within the extractive industry.


AX J1845-0258 is a transient X-ray pulsar, with spin period of 6.97s, discovered with the ASCA satellite in 1993. Its soft spectrum and the possible association with a supernova remnant suggest that AX J1845-0258 might be a magnetar, but this has not been confirmed yet. A possible counterpart one order of magnitude fainter, AX J184453-025640, has been found in later X-ray observations, but no pulsations have been detected. In addition, some other X-ray sources are compatible with the pulsar location, which is in a crowded region of the Galactic plane. We have carried out a new investigation of all the X-ray sources in the ASCA error region of AX J1845-0258, using archival data obtained with Chandra in 2007 and 2010, and with XMM-Newton in 2010. We set an upper limit of 6% on the pulsed fraction of AX J184453-025640 and confirmed its rather hard spectrum (power law photon index of 1.2 +\- 0.3). In addition to the other two fainter sources already reported in the literature, we found other X-ray sources positionally consistent with AX J1845-0258. Although many of them are possibly foreground stars likely unrelated to the pulsar, at least another new source, CXOU J184457.5-025823, could be a plausible counterpart of AX J1845-0258. It has a flux of 6x10^{-14} erg cm^{-2} s^{-1} and a spectrum well fit by a power law with photon index ~1.3 and Nh ~ 10^{22} cm^{-2}.


Human behaviour representation and modelling in Smart Spaces are crucial tasks in Ambient Intelligence environments. A problem found among existing technologies is that the environment sensor data is always provided as crisp events. However, to model behaviour in reactive Smart Spaces we need to identify user patterns, which are not always performed in the same way or happening at the same time/frequency. Hence, the handling of imprecision is essential to model human behaviour in a realistic way. In order to connect these two paradigms, we suggest a combined architecture to fill the gap between quantitative Smart Space architectures (which provide raw crisp events) and qualitative aspects such as fuzzy reasoning and learning algorithms, that extract intelligence from data. With this aim, we propose to use Semantic Web principles of independence and interoperability to build an integrated framework to take advantage of the benefits of both crisp and fuzzy models. Our contribution in this work is a proof of concept to demonstrate how a hybrid architecture, with a reactive rule-based subscription mechanism, can empower users to model everyday activities semantically or control what happens on their surroundings, among other advantages.


A number of national governments, including the UK, have successfully implemented a change to accrual accounting. But the change should not be regarded as an end in itself: it will not solve the problems that arise where inadequate cash accounting systems exist; it will not improve control or management where inadequate control and poor management exist; nor will it improve external audit or the legislature's control over the executive. Before this reform is introduced, cash accounting should be robust, control should be secure, external audit should be functioning well and the legislature should have an ability to call the executive to account. This article sets out preconditions that governments need to meet to ensure that the full benefits of accrual accounting are achieved.


Inverse Kinematics has been recognized as an important problem in robotics applications. A robot independent solution can only be obtained through numerical methods, but most solutions which use this approach have problems with convergence especially near singularity points. This article develops a strictly convergent algorithm and a special-purpose Inverse Kinematics Processor (IKP) to obtain the solution in real time. While the algorithm is based on open-loop integration of rates, the absolute position deviation is used as a criterion to control the iteration, and a feedback mechanism has been especially designed to eliminate problems with long-term drift or with initial errors in the solution. The architecture of the IKP is based on a high-speed floating-point arithmetic processor and is designed to perform the common matrix-vector operations efficiently with a minimum processor cycle time. The algorithm has been simulated on the proposed architecture, and the results show its robustness and real-time capability. For a six degree-of-freedom robot manipulator (for which no closed-form solution exist), the Inverse Kinematics solution may be obtained at an approximate 2 khz rate with an error which is within standard repeatability limits.


Artifact evaluation is an established peer review practice in several fields of computer science research. In the security field it only has been introduced recently. The author highlights several benefits of artifact sharing for and beyond the research community, inspects the specifics of the security field, and derives suggestions to foster artifact sharing in the security field. Embracing artifact sharing will help to strengthen and mature the field.


The current research explores executive function (EF) development among the children at the University Of Rhode Island's child development centers (CDCs). Specifically, the research explores the role of outdoor play in executive function development. Two samples of children from the Providence Child Development Center and the Kingston Child Development Center are compared twice (time 1 and time 2) across 5 months to assess the role of outdoor play spaces in executive function development. The independent variable, playground type has two levels: a playground structure (Kinsgton CDC) and open outdoor space (Providence CDC). Executive function is assessed using three tasks, the Day/Night task, the Backwards Digit Span, and the Standard Dimensional Change Card Sort Task (DCCS). Findings reveal no significant difference between the two samples at time 1 and time 2. Results suggest an outdoor playground does not provide greater benefits for executive function development than the use of an open space. Results can be used to inform educators regarding the use of outdoor space for playtime.


In this paper, the detection of T5 tubular fluorescent lamps (FLs) is carried out with a self-oscillating electronic ballast. The developed topology identifies and operates different lamps with their rated powers. A single-ended primary-inductor converter (SEPIC) is used for power factor correction (PFC), with a half-bridge inverter to supply the lamps. The lamps detection is realized by means of an analog electronic circuit. The command of the switches of the PFC and inverter stages is accomplished by the self-oscillating circuit. Experimental results, as well as an analysis of the data referring to compliance with the technical standard NBR 14418 are presented in relation to preheating of the T5 FLs electrodes.


The purpose of this paper is to study with the help of Noether's theorem the symmetries of anisotropic actions for arbitrary fields which generally depend on higher order spatial derivatives, and to find the corresponding current densities and the Noether charges. We study in particular scale invariance and consider the cases of higher derivative extensions of the scalar field, electrodynamics and Chern-Simons theory.


The healing status of chronic wounds is important for monitoring the condition of the wounds. This article designs and discusses the implementation of smartphone-enabled compression technique under a tele-wound network (TWN) system. Nowadays, there is a huge demand for memory and bandwidth savings for clinical data processing. Wound images are captured using a smartphone through a metadata application page. Then, they are compressed and sent to the telemedical hub with a set partitioning in hierarchical tree (SPIHT) compression algorithm. The transmitted image can then be reduced, followed by an improvement in the segmentation accuracy and sensitivity. Better wound healing treatment depends on segmentation and classification accuracy. The proposed framework is evaluated in terms of rates (bits per pixel), compression ratio, peak signal to noise ratio, transmission time, mean square error and diagnostic quality under telemedicine framework. A SPIHT compression technique assisted YDbDr-Fuzzy c-means clustering considerably reduces the execution time (105s), is simple to implement, saves memory (18 KB), improves segmentation accuracy (98.39%), and yields better results than the same without using SPIHT. The results favor the possibility of developing a practical smartphone-enabled telemedicine system and show the potential for being implemented in the field of clinical evaluation and the management of chronic wounds in the future.


The Rh blood group system, which is the most polymorphic of the blood group systems, is of major importance in transfusion medicine. The partial D phenotypes are classified into different categories according to the absence of one or more D epitopes. Most partial D phenotypes are generated from gene conversion events between the RHD and the RHCE genes. The low-frequency antigen, Rh23 (Dw), is characteristic of the DVa category.1 The DVa red cell (RBC) is also characterized as being negative when tested with monoclonal antibodies (MoAbs) to epitopes D1 and D5 in the 9epitope model.2 The molecular basis for the DVa category has been reported, in which either the entire RHD exon 5 (DVa Hus) or a portion of it (DVa Kou) was replaced by the RHCE equivalents.3 Recently, we reported the presence of a new RHD variant (DVa-like) that closely resembles the DVa category both structurally and serologically.4 In that study, we attempted to detect the expression of Rh23 on the DVa-like RBC membrane by using a polyclonal anti-Rh23 from a donor of blood group A. After the absorption test, the antibody reacted with a control DVa category RBC in an indirect antiglobin test, showing a higher titer, and was negative with normal RBCs. Rh23 was detected on the RBC membrane in three DVa and six DVa-like individuals. These results showed that the DVa-like sample was categorized as DVa category (Table 1). Various amino acid (aa) substitutions existed on the fourth loop of the Rh polypeptides in the DVa category. Detection of Rh23 on the RBC membrane is necessary for classification of the DVa category. The molecular structures of the mutated RHD genes from the DVa (Jpn) and the International Society of Blood Transfusion (ISBT) 49 categories were very similar.4,5 Both phenotypes exhibited four aa substitutions as compared to the aa sequence in the intact D polypeptide: Phe223Val, Glu233Gln, Val238Met, and Val245Leu. However, one aa difference (Ala226Pro) between these two phenotypes was found on the fourth external loop of the D polypeptide. It is known that Pro226 and Ala226 are the E/e polymorphism in the CE polypeptide. This result indicated that the hybrid RHD-CE-D genes of DVa ( Jpn) and ISBT 49 generated through a gene-conversion event were derived from the RHe and RHE genes, respectively. Avent et al.5 also described ISBT 49 as negative when tested with some epitope D8 MoAbs. We threorized that DVa (Jpn) was different from ISBT 49. A previous study3 proposed that the aa residing at position 233 was probably involved in the Rh23 epitope, because the difference in the extracellular region between the D polypeptides and those of the DVa category was only at aa 233 (Glu/Gln), while the other aa substitution at 223 (Phe/Val) was located in the intramembrane domain in all DVa RBCs. In our previous study,4 one aa substitution was detected at 233 on the fourth loop of the Rh polypeptide in S.M. and H. K. individuals. In this serologic study, the S.M. sample with the Glu233Gln substitution was serologically positive for Rh23, while the H.K. and M.I. samples with the Glu233Lys substitution were negative (Table 1). These results suggested that Rh23, which can be expressed on the RBC membrane, results from only one aa substitution (Glu233Gln) in the D polypeptide. We also described the reactivity of the partial D RBCs (in 9-epitope model) with MoAbs (Table 2). The DVa (Jpn) category was confirmed by the lack of epitopes D1 and D5 in this study. Then, the DVa (S.M.) RBCs were negative with MoAbs to epitope D1 and with one MoAb (P3X35 [Table 2]) to epitope D5. This result may indicate that the substitution Glu233Gln was associated not only with the expression of Rh23 but also with the loss of epitopes D1 and D5 in the DVa (S.M.) sample. We also showed that one substitution, Glu233Lys in new partial D phenotype, DHK, results in the lack of various RhD epitopes (Table 2). Negative reactions were observed with MoAbs to epitopes D1, D4, D5, D6/7 (a part), and D9 (a part). This information will allow further study of the epitopes of D.


There are conflicts between Article 58 of " Railway Law of The People's Republic of China" and Article 123 of the "General Principles of Civil Law of The People's Republic of China".The paper clarifies the hierarchy between "basic law" and "other laws" first and then deals with the protection of the interests of vulnerable groups in the railway traffic accidents as well as considering corporate social responsibility.It holds that Article 123 of the General Principles of Civil Law of P.R.C.should be given the first priority.


(NOTE: Each chapter begins with an introduction and concludes with Final Remarks. Some chapters include an Appendix after Final Remarks.) I. Programming Concepts. 1. Parallel Programming Paradigms. 2. The SuperPascal Language. II. The All-Pairs Paradigm. 3. Householder Reduction. 4. The All-Pairs Pipeline. 5. Balancing a Pipeline. 6. The N-Body Pipeline. III. The Multiplication Paradigm. 7. The Multiplication Pipeline. IV. The Divide and Conquer Paradigm. 8. The Fast Fourier Transform. 9. Parallel Divide and Conquer. 10. Hypercubes and Tree Machines. V. ThheMonte Carlo Paradigm. 11. Simulated Annealing. 12. Primality Testing. 13. Multiple-Length Division Revisited. 14. Parallel Monte Carlo Trails. VI. The Cellular Automata Paradigm. 15. Laplaces Equation. 16. Parallel Cellular Automata. VII. Parallel Model Programs. 17. Complete SuperPascal Programs. Bibliography.


Specific heat of layered NaxCoO2 single crystals (x = 0.76–0.87) down to 100 mK and the dc‐susceptibility down to 2 K in magnetic field applied parallel to the layers has been measured. The specific heat data of single crystals of exceptional high quality with 0.71 ≤ x ≤ 0.747 reported in L. Balicas et al. [Phys. Rev. Lett., 100, 126405 (2008)] with the kind permission of the authors have been also analyzed. Non‐Fermi liquid (NFL) features observed in Na concentration dependent temperature region have been analyzed and discussed in terms of disorder induced NFL behavior with quantum Griffiths phases in the background. The phase diagram is proposed, the results indicate possible quantum critical point below x = 0.7 and closeness to metal–insulator transition at doping above x = 0.87.


The superconducting transition temperature T/sub c/, the perpendicular critical magnetic field H/sup perpendicular//sub c/, the electrical resistance, and the structure of vanadium films obtained by ionic evaporation in an ultrahigh vacuum apparatus were investigated. A carbon sublayer and coating of 15 A thickness were applied in order to protect the samples against external influences. The critical fields were measured by the resistive method. Upon a decrease of film thickness from 2900 to 60 A a reduction of T/sub c/ from 5.1--5.2 to 2.4 K was observed, along with an increase of the residual resistivity rho/sub n/ from 4.5 to 20 ..mu..ohm-cm and an increase of the derivative vertical-bardH/sup perpendicular//sub c//dTvertical-bar near T/sub c/ from 3.6 to 6.7 kOe/K. No superconductivity was observed in a film of 30 A thickness down to 1.3 K. The type of crystal structure and the lattice constant for 125--1000 A thick films, determined by the technique of electron diffraction, are the same as those for bulk samples of vanadium; the grain size in these films amounted to 500 to 800 A. The electron density of states N (0), calculated on the basis of the data concerning vertical-bardH/sup perpendicular//sub c//dTvertical-bar and rho/sub n/ for thick filmsmore » (720 to 2900 A), agrees with the value of N (0) for bulk vanadium (if it is assumed that coefficient, which takes account of the correction due to strong coupling effects for H/sub c//sub 2/, is given by eta=1.2). Upon a reduction of the film thickness to 60 A, N (0) is reduced by approximately a factor of two. The results agree with the assumption that strong variations of N (0), having an influence on T/sub c/, can be observed in transition-metal films due to a reduction in the electron mean free path. The obtained quantitative information with regard to N (0) in thin vanadium films (d< or =250 A) is sensitive, however, to the presence of a hypothetical surface transition layer and to its properties and thickness.« less


The second stage of labour is associated with relative fetal hypoxia and progressive metabolic acidosis. Maternal analgesia can increase the danger, especially for the high-risk fetus. In 152 patients the effect on the fetus of pethidine alone, pethidine + trichloroethylene, or pethidine + Entonox was assessed by fetal scalp blood sampling. Fetal pH, Pco2, and Po2 were measured and base excess was calculated. Capillary samples were also taken 45 to 60 minutes after birth in 88 of the babies to estimate the rate of neonatal recovery. Entonox proved safer than trichloroethylene, and babies treated with it maintained their Po2 before birth, had better Apgar scores at birth, and one hour later were significantly less acidotic and much better oxygenated.


Disclose cathode materials for thermal batteries. Such cathode materials includes a main active material, and a bimetallic sulphides such as a specified amount of CuFeS Cells containing such cathode material (e.g., thermal batteries) is also disclosed.


We study the existence of one or more weak periodic solutions of nonlinear evolution PDEs in a cylinder of RN+1 with conditions on lateral surface by using the results connected to a general evolution variational equation depending on a parameter.


An intracranial hemorrhage resulted in fetal hydrocephalus. Antepartum fetal heart rate monitoring instituted for decreased fetal activity led to this intrauterine diagnosis. The infant had no neurologic delay at 16 months of age.


According to Isomorphism in Gestalt theory, this paper holds that taking "force" into consideration may solve the problem of how to convey "spirit" through "form". That is, to achieve "spirit likeness" in literary translation, we must first analyse the forces of "spirit", "meaning" and "structure" in the ST, and then try to integrate the forces of "spirit", "meaning" and "structure" in the TT.


The invention discloses an evaluation result obtaining method and a condition evaluation server. The method comprises the following steps: a received request message is analyzed to obtain an evaluation object, evaluation conditions and evaluation setting; and the related information of the evaluation object is evaluated according to the evaluation setting and the evaluation conditions; and a notification message carried with the evaluated result is sent. The embodiment of the invention obtains the evaluation object, the evaluation conditions and the evaluation setting by analyzing the received request message and feedbacks the detailed evaluated result to client-sides corresponding to group members after determining the group members meeting the conditions through condition evaluation.


This study attempts to identify causal factors that impact the airport acceptance rate (AAR) and derive a statistical model that accurately predicts AARs using these factors. Airports included in the study are EWR, JFK, LGA, DFW, ORD, LAX, SEA, and SFO. The variables tested in the study include scheduled traffic demand and fleet mix, weather phenomena, and airport characteristics. Findings suggest that discrete variables that describe a range of values, such as number of active runways, runway configuration, and controller-input meteorological conditions, more accurately predict AARs than continuous variables such as visibility and ceiling.


Two new Zn(II) complexes, [Zn(L)2(H2O)2] where L is 1-substituted 5-methyl-1H-[1,2,3]-triazole-4-carboxylic acid, have been synthesized and characterized by elemental analysis, FT–IR, and solid-state fluorescent emission spectroscopy. Structures have been established by single-crystal X-ray diffraction, revealing the discrete nature of the complexes in which Zn centers adopt slightly distorted octahedral geometry. In the complexes, the 1-substituted 5-methyl-1H-[1,2,3]-triazole-4-carboxylic acid is bidentate.


While taking an MRI scan, the patients cannot static for a long time during the motions; the image formation process can create artifacts that may reduce the image quality. The Compressed Sensing (CS) mechanism is employed to reconstruct the original image from the limited data given as the sparse matrix. Hence, CS can be utilized to reduce the acceleration time for an MRI scan considering the patient's health. So the sensing method is implemented by a suitable projection matrix for reconstructing the sparse signals from a few numbers of measurements using Compressed Sensing. The CS guarantees the recovery of the original image with high probability based on random Gaussian projection matrices. However, sparse ternarius projections are more apt for the implementation of hardware. In this article, the proposed deep learning method is employed to obtain a very sparse ternary projection in Compressed Sensing. Compressed Sensing Reconstruction using an adaptive scale parameter based on the texture feature is used to improve the image quality. The two scaling factors αx and αy are assigned to specify the fixed scale for changing the improvement of the image quality. In the parameter using texture feature, the αx and αy are assigned to α as an adaptive scale based on texture feature. In the TACS-SDANN architecture, there are two layers namely the sensing layer which trains the projection matrix and a reconstruction layer which trains for non-linear sparse matrix continuously using Auto-encoder. Experimentally, the scaling factors are calculated on the training data to get the mean PeakSignal-to-Noise Ratio (PSNR) for improving the image quality. Hence a new deep network layer is employed to improve the image quality in this proposed method. Hence the consequence of the proposed method is compared with the SDANN method based on the mean Peak-Signal-to-Noise Ratio (PSNR) to check the image quality. From that comparisons, the TACS-SDANN architecture is proposed to yield a better performance.


The northern corn rootworm, Diabrotica longicornis (Say), adult was found to oviposit in the soil between plants within a row of maturing corn fields. Eggs were found in decreasing numbers at 4, 8, and 10 inches from the row but none were found in the middle between 40-inch rows. The depth of egg deposition is probably governed by the degree of soil cracking, but an average of 4 samples in 1963 and 1964 showed 92.8% of the eggs in the top 4 inches of soil. In a separate study, 88% of the eggs were noted in the upper 3 inches of soil, but after plowing to a depth of 9 inches, all eggs were recovered from the 3- to 9-inch layer. Sampling between plants in several fields before plowing showed 19-558 eggs per 100 cubic inches of soil 4 inches deep. Subsequent larval counts indicated 0.19 larva per egg detected by the particular egg assay employed. Hatch occurs in northern corn rootworm eggs after diapause is broken by low temperatures, but hatch was found to be reduced or prevented when the microclimate was –2°C or below for 6 or more weeks. Spring-collected eggs held in a refrigerator (around 4.4°C) for 24 months displayed a normal hatching pattern when removed to ambient laboratory temperatures. Eggs taken from the field in early spring showed first hatch in 15.3 days when held at 25°C, but when spring-collected eggs were held at 4.4°C for 8 months first hatch occurred 9.7, 14, and 18 days after being placed at temperatures of 26.7, 22.8, and 18.3°C, respectively. This fact might indicate some physiological development of diapause-free eggs retained at 4.4°C. No eggs hatched when incubated at 31.7 or 33.9°C. Contact moisture was employed for all studies on embryonic development. Laboratory-produced eggs retained at ambient laboratory temperatures displayed 13.3% hatch in the absence of a chilling period. Likewise, eggs collected from the field on October 12 showed 21.4% of the eggs free of diapause.


The optimum processing conditions for the manufacture of polymer-modified bitumens (PMBs), as well as the rheological properties of the final polymer-bitumen blends, strongly depend on the characteristics of the mixing device used. The present work is focused on the comparison among the kinetics of the mixing process and the rheological properties and microstructural characteristics of PMBs manufactured in two different mixers. Thus, blends of 60/70 penetration grade bitumen and recycled EVA/LDPE were processed in both high and low-shear devices. Knowledge on the evolution of shear viscosity and microstructure with time, as well as on the mechanical properties of the final polymer-bitumen blends, was gained from rheological and modulated DSC tests, and optical microscopy. The results obtained demonstrate that processing in the high-shear device yields a significant decrease in the time needed for the polymer-bitumen blend to reach the final stage of the manufacturing process, as well as an important reduction in bitumen oxidation and enhanced properties in a wide range of in-service temperatures. However, polymer-bitumen blends manufactured in the high-shear device are not stable during its storage at high temperature. POLYM. ENG. SCI., 47:181–191, 2007. © 2007 Society of Plastics Engineers


The unstable state or phenomena may be defined as a situation obtained by contiguous disturbances in parameters of the system. There are a variety of methods to explain these processes. We presented in the current paper the work out theoretical investigations, related to the instability conditions and vortex formation in the accretion discs. We pointed analysis of observational data, which is not relevant to our theoretical studies. Binary star systems with accretion disc produce light curves that may give us information about the behavior and structure of the mass flow. We use the specialized method to calculate lightcurves of the selected binary stars, based on the observational data. From the results of created images and the shape of light curves it is concluded for the nature of instabilities in accretion disc flow.


This paper deals with the aspects of managerial perception and understanding of the success of the open innovation concept and its impact on the sustainability of public institutions. Major French (and global) Agrobiotech Institutes were selected for the qualitative analysis to understand its managers' position in terms of open innovation concept and how it might contribute to the sustainability of the public institutions. Findings indicate that balanced activities of creation of social values and commercialization of the effects are perceptions for sustainability strategy of academicians and managers that were interviewed.


In Wireless Visual Sensor Networks (WVSNs), node selection and organization to realize applications is the title of some research fields known as network topology models that can be classified into two main categories of single-tier and multi-tier. According to the literature, only multi-tier topology model is able to provide a balance between WVSNs objectives such as low cost, maximum coverage, minimum energy consumption, high functionality, and good reliability. In a general architecture for this model, the lowest tier consists of scalar nodes that can activate camera nodes of upper tier only if necessary. However, regarding the inter-tier communication radio range and camera nodes' covered area, in many cases the activated cameras do not detect any objects. The mentioned problem which wastes energy and processor time for doing unneeded image capturing and object detection operations is introduced for the first time in this paper. Besides, a new clustering method with the aim of determining the scalar nodes located inside the area covered by a camera node is proposed as a solution. As the simulation results indicate, this solution has succeeded in saving camera nodes' energy and prolonging network lifetime.


This is a review of the 4 th session of the seminar "Social philosophy and the development of civil society in Russia", which took place on February 11, 2006, at the Institute of Philosophy, Russian Academy of Sciences. Doctor of Philosophy, Professor I.K. Pantin presented a paper titled "Civil society and the issues of its rise in Russia".


The low frequency response and damping behavior of four quantum well (4QW) graded-index separate confinement heterostructure (GRINSCH) and SCH strained-layer lasers are compared. The SCH laser is shown to be better in both respects due to a shorter carrier capture time into the quantum wells. A record 3-dB bandwidth of 28 GHz is reported for a 150 micrometers cavity length 4QW strained-layer SCH laser. The change in the differential gain, non-linear gain coefficient, and damping rate are studied as a function of the quantum well thickness and barrier height. It is found that decreasing the well thickness does not change the non-linear gain coefficient nor the differential gain appreciably in relatively deep wells. Shallower quantum wells, however, are observed to have lower differential gain and a higher damping rate.


The study of nutritional requirements of team sports athletes is growing considerably in recent years, allowing determining their nutritional needs both, in training and competition. However, scientific research does not seem to progress in the same way with Paralympics team sports, such as wheelchair basketball. Scientific literature does not allow determining the most effective nutritional practices to improve performance and recovery of these athletes nor to reduce the incidence of injuries other than the chronic disability of the subjects [1,2].


Health data science aims to extract knowledge from data allowing better decision-making, using multidisciplinary approaches from fields such as computation, statistics, epidemiology, and several medical knowledge domains. We live in the 'big data' era, with a growing availability of health data, in volume, variety, and velocity, also for tasks such as kidney transplantation. Hereby, secondary use of this health data must be encouraged to improve patient care planning, disease research, and policymaking around transplantation. This article presents the Transplant Open Registry (TxOR) website where some health data science applications on kidney transplantation are available. With it, we try to answer, some of the remaining questions on kidney transplantation in Portugal, with a new approach.


This paper describes the use of street storage systems to prevent combined sewer surcharging and mitigate basement flooding. A case study approach, based primarily on two largely implemented street storage systems, is used to explain the concept through construction and operation aspects of street storage systems. Street storage refers to the technology of temporarily storing storm water (in densely urban areas) on the surface—off-street and on-street—and, as needed, below the surface close to the source. Close to the source means where the water falls as precipitation and prior to its entry into the combined, sanitary, or storm sewer system. The idea is to accept the full volume of storm-water runoff into the sewer system but greatly reduce the peak rate of entry of storm water into the system. System components include street berms, flow regulators, and surface and subsurface storm-water storage facilities. By eliminating surcharging in combined sewer systems, street storage has the potential to cost-ef...


Reperfusion injury following transplantation is the major cause of graft dysfunction and may lead to significant morbidity and mortality to patients. Lymphocyte recruitment and activation are crucial in the propagation of hepatic ischemia-reperfusion (I/R) injury; however, the roles of specific lymphocyte subpopulations and cytokines secreted during this process are poorly understood. Interleukin 17 has been implicated in the progression of several inflammatory conditions, including inflammation associated with I/R in animal models. Living donor (LD) livers suffer less reperfusion injury compared to brain death heart-beating donor (HBD) allografts. We aimed at defining IL-17 producing T cells deriving from donor livers from HBD and LD transplants. Material and Methods Hepatic mononuclear cells (HMNCs) were separated by Ficoll density centrifugation from liver perfusate obtained during the transplant procedure. Characterization of HMNCs using antibodies against B, T cells, regulatory T cells, conventional NKT cells, dendritic cells (DC) and cells bearing T receptor gamma/delta and alpha / beta was performed using flow cytometry (FACS). Additionally, T cell lines/clones were generated from both donor livers and the level of IL-17 in culture supernatant was assessed by ELISA. Results Both cells deriving from HBD (n=10) and LD (n= 10) liver perfusate had high proportions of CD8 and low proportions of CD4 T lymphocytes, indicating their hepatic origin. The frequency of T cell subsets and other cells was different between HBD and LD allografts, in particular, the proportions of CD4+CD25high regulatory T cells (0.68±0.09 vs 2.2±0.71) and CD8+/PD-1+ positive T cells (4.8±1.4 vs 8.1±2.8) were significantly lower in HBD than in LD, those cells are known to have suppressive properties. In addition, the proportion of gamma/delta T cells (8.2±1.8 vs 1.6±0.44) and myeloid DC (3.9±1.2 vs 1.24±0.6), which have effector functions, was significantly higher in HBD than LD allografts. The percentage of total IL-17 producing cells of hepatic lymphocytes obtained from the perfusate was higher in HBD than that in LD (5.5±1% vs 1.6±0.4%, p=0.03). Among the T cell lines generated, although the frequency of CD8 and gamma/delta T cells was similar in HBD and LD, their ability in producing IL-17 was significantly higher in HBD compared to LD (100±22 pg/ml vs 23±11pg/ml for gamma/delta cells and 254±86 pg/ml vs 10±8 pg/ml for CD8 T cells). Conclusion Donor derived IL-17 producing CD8 T cells and gamma/delta T cells may be involved in maintaining inflammation triggered by reperfusion injury. These findings may provide useful information for developing future therapeutic strategies aimed at attenuating I/R effects.


PurposeFor an entrant platform in the on-demand service market, choosing an appropriate employment model is critical. This study explores how the entrant optimally chooses the employment model to achieve better performance and investigates the optimal pricing strategies and wage schemes for both incumbent and entrant platforms.Design/methodology/approachBased on the Hotelling model, the authors develop a game-theoretic framework to study the incumbent's and entrant's optimal service prices and wage schemes. Moreover, the authors determine the entrant's optimal employment model by comparing the entrant's optimal profits under different market configurations and analytically analyze the impacts of some critical factors on the platforms' decision-making.FindingsThis study reveals that the impacts of the unit misfit cost of suppliers or consumers on the pricing strategies and wage schemes vary with different operational efficiencies of platforms. Only when both the service efficiency of contractors and the basic employee benefits are low, entrants should adopt the employee model. Moreover, a lower unit misfit cost of suppliers or consumers makes entrants more likely to choose the contractor model. However, the service efficiency of contractors has nonmonotonic effects on the entrant's decision.Originality/valueThis study focuses on an entrant's decision on the optimal employment model in an on-demand service market, considering the competition between entrants and incumbents on both the supplier and consumer sides, which has not been investigated in the prior literature.


The decade has witnessed great importance of numerical techniques for scientists and researchers in deciding the correctness, stability, and reliability of new designs. In the present study a numerical technique has been implemented to investigate the thermo-hydraulic performance of the Louvered winglet tape inside the tube section of the double pipe heat exchanger. The Louvered winglet tape has been examined with the slope angle of 50, 100, 150 and 210 to study their thermal characteristics. The Reynolds number 4000-30000 was examined on slope angle of 50, 100, 150 and 210 to study their flow characteristics in the turbulent domain. A smooth pipe was examined to evaluate heat transfer characteristics in terms of Nusselt number and friction coefficient over augmented tube with Louvered winglet tape. The results show a satisfactory performance of Louvered winglet tape over the smooth tube with a similar trend of friction factor, Nusselt number, and thermo-hydraulic performance index (THPI). The percentage of increment of the Nusselt number of the results is found to be 237.04%, 258.4%, 275.11%, and 289.72% when compared to smooth pipe with respect to slope angle of 50, 100, 150 and 210, respectively. The amount of increase in the friction factor in comparison with plain tube is 5.13, 6.73, 8.33, and 11.73 times of that of smooth pipe with respect to slope angle of 50, 100, 150 and 210, respectively. The Louvered winglet tape with slope angle 150 has shown to be promising with respect to higher THPI when considering with other slope angle of 50, 100, and 210. The maximum THPI of 1.85 was obtained for slope angle 150 at Re 12000. Similarly, the THPI values for other slope angle 50, 100, and 210 are 1.71, 1.78 and 1.69. In addition to better performance the Louvered winglet tape can be easily fabricated and adapted for a wide variety of heat transfer industries.


Demonstrating how race is socially constructed has been a core sociological objective, yet many individuals continue to hold essentialist and other concepts of what races are and how to account for group differences. These conceptualizations have crucial consequences for intergroup attitudes, support for social policies, and structures of inequality, all of which are key sociological concerns; yet much of the research in this area has emerged outside of sociology. Our review of this interdisciplinary scholarship describes the range of views people hold, the attitudes and behaviors associated with them, and what factors contribute to these views. We focus primarily on essentialism and constructivism, although we describe the greater variety of beliefs beyond this dichotomy, as well as fluidity in how people use these concepts. We conclude by presenting research on strategies for reducing essentialist belief systems and identifying key areas for future research. Expected final online publication date for the Annual Review of Sociology, Volume 49 is July 2023. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.


For most of us, the juvenile court has existed all our lives. Even so, most people do not understand it very well and it has never been given the tools to do its job properly. Many judges are unprepared for their tasks when they assume juvenile court responsibility; there are not enough probation officers with adequate training; and detention services often produce delin quency. Nevertheless, juvenile court maturity can be achieved if we are willing to work at it.


The present invention relates to a method for preparing Periplaneta americana extract, comprising soaking degreasing petroleum ether, then water extraction and alcohol precipitation by alcohol extraction or extraction water sedimentation method, and other steps added acceptable excipients. The preparation method is simple, easy to operate, the paste preparation process, high yield, product clear, high total amino acid content, provides a new option for the clinical Periplaneta americana extract was prepared.


We reported one case of CLL/PL with prolymphocytic transformation and observed the effect of fludarabine on it. The patient was first admitted for nonspecific hematological symptoms. Her bone marrow showed a mixture leukemia cell's group consisted of 30% prolymphocytes and 50% mature small lymphocytes. Datas of MIC assay were analyzed. Phenotype indicated some prolymphocytic features. The patient was diagnosed as CLL/PL and a traditional chemotherapy regimen mainly consisted of CHOP and leukeran was applied but showed very limited effect. One month later she was admitted once more for aggravating anemia. MIC was examined again and showed a high proportion of 60% prolymphocytes in marrow. Phenotype by FCM indicated a double positive expression of FMC7 and SmIg. The patient was diagnosed as prolymphocytic leukemia transformed from CLL/PL. Chemotherapy based on CVP and leukeran received no good response. So a single-agent regimen of fludarabine (30 mg*m−2*d−1 IV for 5 days as one cycle) was tried. After two cycles' chemotherapy, bone marrow was reevaluated. Proportion of prolymphocytes descended to a level of 1% and a mild bone marrow suppression was accompanied. Nearly half a year's follow-up showed a sustained blood tri-linage low level and the patient still led an acceptable quality life with packed red cell support once a month.


The general strike and its aftermath nationalism confronts trade unionism "Viva NAFAU" - the emergence of the NUNW the early years of independence.


In modern society, it is reported that overstress has been one of obstacles to human body's mental and physical health. For instance, so-called lifestyle-related diseases (cancer, hardening of the arteries, hypertension, diabetes, etc.) are mainly caused by active oxygen and free radical formed excessively in body, which induce various diseases that are caused by cell damages because of protein denaturation, lipoperoxidation, nucleolytic degradation and enzyme inactivation. Recently, health-consciousness has been promoted and it is highly accepted that it would be beneficial to take traditional food in which there are active compositions for prevention of disease or for antiaging. Lichen has been utilized for food since the ancient time and is considered to contain its special compositions because of its growth as homobium of fungi and algae. It is also reported that lichen is effective to inhibit lifestyle-related diseases such as hypertension and hypercholesteremia. Physiological Activity of Chinese Lichen (Gyrophora esculenta) Component, Methyl 2,4-Dihydroxy-6-methylbenzoate and the Related Compounds


The authors develop a dynamic network model of collective action that explains how collective action can arise in the absence of selective incentives or disincentives from the voluntary action of rational actors in large groups. They show that the search for balance in social interaction among interdependent actors can yield a cascade of activism and result in a successful social movement. The characteristics of actors critical for movement success are identified. They also explore the structural conditions underlying a successful cascade of activism and thus identify the social dynamics of and the structural conditions for collective action in human society


PTS has been reported to have a very large non-resonant nonlinearity by a number of groups, making it a prime candidate for applications in nonlinear optics.[1-6] At 1064 nm there have been a number of measurements published for both the nonlinear refractive index coefficient n2 and the two photon absorption coefficient β2.[2-6] Although the published two photon coefficients agree with each other to within a factor of two, the values for n2 vary over more than one order of magnitude. As a result the two photon figure of merit, T, which is used to assess the effectiveness of a material for nonlinear optics varies from 0.3 to 22. This parameter needs to be less than unity and hence it is not clear whether this material will be useful or not. In this paper we report on detailed z-scan measurements of the nonlinearity in single crystal PTS at 1064 nm.


Pay and labour productivity growth in Canada are broadly aligned over the long run since 1961 and during the 2008-19 business cycle. The slowdown in Canada's productivity growth rate since 2000, the general stability of the labour share, and the lack of further gains in labour's terms of trade after 2008 largely explain the slowdown in workers' real pay growth over the 2008-19 business cycle. Canadians should be concerned about the country's persistently low productivity growth because it leads to low real pay growth. Canada's policymaking institutions should prioritize understanding and accelerating productivity. This article examines the long-run relationship between growth in labour productivity, defined as real output per hour worked across the total economy ("productivity"), and growth in average workers' pay, defined as real hourly total labour compensation ("pay").2 When both concepts are carefully measured, productivity and pay in Canada have broadly kept pace with each other in aggregate over the long run and across business cycles. The economy-wide link between growth in productivity and pay appears foundational and intact.3 The main contribution of this article is to present new evidence for Canada building on Sharpe et al. (2008a). In comparision with that study, and also Dufour and Russell (2015), Uguccioni et al. (2016) and the Canadian results in Harrison (2009) and Sharpe and Uguccioni (2017), this article uses: total economy average labour compensation (including supplemental labour income and the labour income of the selfemployed) as the sole, comprehensive measure of nominal pay. To construct real pay, 1 Vice President of Policy at the Business Council of British Columbia. The author thanks Andrew Sharpe, Jock Finlayson, Ken Peacock and four anonymous referees for helpful comments, and Wulong Gu from Statistics Canada for providing historical data. Email: email@example.com. 2 Hereafter, "productivity" and "pay" refer to levels, and growth refers to their change over time. An acceleration (deceleration) in levels is an increase (decrease or slowdown) in growth rates. 3 The analysis does not consider changes in the distribution of pay across income groups, firms, regions, industries, skills, or socioeconomic characteristics. It is noteworthy that although income inequality did increase in Canada during the 1980s and 1990s, the Gini coefficients for market incomes and disposable incomes peaked in 1998 and 2004 respectively (Statistics Canada, 2021). In other words, Canada appears unlike the United States (Mishel and Gee, 2012) in that household income inequality has been declining for about two decades. INTERNATIONAL PRODUCTIVITY MONITOR 3 the study uses the household consumption expenditure deflator (HCE) in addition to the GDP deflator (PGDP) and the consumer price index (CPI). The study also excludes depreciation and output-based taxes from the measure of total economy output in labour productivity. Sharpe et al. (2008a) consider the five Canadian business cycles over 1961-2007 but the main analysis is focused on 1980-2005 which predates most of the boom in Canada's external terms of trade from 2002-08. This article examines a longer time period of 19612019 and includes six business cycles, including the 2008-19 cycle. Sharpe et al. (2008a) concluded that hourly median real earnings of full-time workers deflated by the consumer price index (CPI) had lagged productivity by 1.26 per cent per annum during 1980-2005. They attributed about half of the gap to the incompleteness of the wage measure and an increasing gap between median and average earnings. By focusing solely on average total labour compensation (and comparing it to productivity which is also an average), this article does not consider those factors. Of the remaining gap, Sharpe et al. (2008a) attribute almost twothirds to a decline in labour's terms of trade and the rest to a decline in the labour share (the ratio of nominal labour compensation to nominal output). The longer time period and measurement choices in this article provide new evidence about these relationships for Canada. The structure of the article is as follows. The first main section surveys the literature. Section 2 sets out the neoclassical theory of the firm on the relationship between pay and productivity. Section 3 addresses measurement issues. Section 4 provides the results using annual Canadian data. Section 5 discusses the findings. Section 6 discusses the policy implications. Section 7 concludes. The Appendix provides data sources and descriptions.


INCORPORATION OF CpG OLIGODEOXYNUCLEOTIDES INTO α2-MACROGLOBULIN: DEVELOPMENT OF A NOVEL VACCINE ADJUVANT DELIVERY MECHANISM by Ryan Berger Anderson Department of Pathology Duke University Date:_______________________ Approved: ___________________________ Salvatore V. Pizzo, M.D., Ph.D., Chairman of Committee ___________________________ George J. Cianciolo, Ph.D. ___________________________ Soman N. Abraham, Ph.D. ___________________________ Herman F. Staats, Ph.D. ___________________________ Jeffrey R. Dawson, Ph.D. An abstract of a dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Pathology in the Graduate School of Duke University 2007 Copyright by Ryan Berger Anderson 2007


Water yield and purification are important aspects of water ecosystem services, and achieving a balanced development of the two is necessary for the development of aquatic ecosystems. Using the InVEST model, the spatiotemporal variations of regional water yield and purification services in Shanxi, China, from 2000 to 2020 were analyzed. Three future scenarios (natural development, urban development, and ecological protection) were assessed for 2030 using the PLUS model. The results showed that in 2000–2020, the water yield of Shanxi Province in terms of space was generally low in the middle and northwest and high in the southeast, and it was affected by land-use change and climatic change. From 2000 to 2020, the water yield of Shanxi Province changed by 78.8 mm. In 2030, water yield will be highest under the urban development scenario (380.53 mm) and lowest in the ecological protection scenario (368.22 mm). Moreover, the water quality purification capacity improved, with nitrogen loading high in the center and low in the east and west. Due to the implementation of environmental protection policies and the improvement of the technical level, the nitrogen load was the highest in 2000 (0.97 kg/hm2) and lowest in 2015 (0.94 kg/hm2). By 2030, because of the high nitrogen loadings of cultivation and construction land and low nitrogen loadings of forests and grasslands, the nitrogen load was lowest under the scenario of urban development (0.94 kg/hm2) and highest under ecological protection (0.85 kg/hm2).


442 Kidney diseases are associated with an estimated 188 million cases of catastrophic health expenditure in lowand middle-income countries.1 The scale of the burden associated with this condition in these countries demands action. Kidney diseases disproportionally affect disadvantaged populations2 and reduce the number of productive years of life.3 Furthermore, the prospect of financial burden discourages many patients from undergoing treatment, thereby leading to preventable morbidity and death. The impact of kidney diseases has been quantified in India, in a cohort of 119 working-age dialysis patients, most of whom lacked health insurance.4 In this cohort, 35/119 (29%) patients died and 16/119 (13%) discontinued dialysis within 12 months. Despite receiving highly subsidized treatment, dialysis patients receiving care in these two sites in northern India still faced high medical out-of-pocket costs: 87.1% of patients in public hospitals were spending over 100% of their monthly income on dialysis compared to 78.9% of patients in private care.4 This expenditure excluded non-medical costs, which can also be substantial.5 As part of its agenda to achieve universal health coverage (UHC) by 2022, the Indian government has committed to establishing at least one eight-station dialysis unit in each of its 688 districts, and is offering free haemodialysis to people living below the poverty threshold.6 The government's ability to meet this commitment will depend not only on increasing its fiscal capacity, but also on the implementation of frugal innovations (such as low-cost dialysis machines7 and greater use of non-physician health workers), enhanced early screening interventions8 and better access to home-based peritoneal dialysis. Better access to peritoneal dialysis would potentially mitigate the substantial non-medical costs associated with travel and lost productivity to attend haemodialysis units.5,6 While financing reforms to implement UHC are critical to enhancing financial protection of patients with chronic kidney disease, these reforms are not enough. Dialysis and transplantation are highly unaffordable in most lowand middle-income countries, particularly for vulnerable groups.6 Comprehensive health benefit packages must prioritize early screening and treatment of risk factors such as diabetes and hypertension, access to essential medicines and the implementation of public health interventions to prevent disease progression.8 Targeted support programmes are also needed as part of a comprehensive strategy to strengthen financial protection for chronic kidney disease patients. One such programme has been introduced by the Government of Andhra Pradesh and provides grants of 2500 Indian rupees (35 United States dollars) to eligible chronic kidney disease patients to offset out-of-pocket costs,9 providing a potentially useful model for other Indian states. Coverage for kidney disease care represents perhaps the greatest challenge in achieving UHC in India and most other lowand middle-income countries.10 This is due to the high cost of existing treatments, high disease burden and constrained financial resources. While reforms are needed to better finance health-care services, including dialysis, much can be done to address the economic burden through greater emphasis on prevention and the development of low-cost treatments.7 Most individuals who currently have chronic kidney disease in India face catastrophic health expenditure.1 Achieving UHC will enable timely access to care and prevent thousands of households from falling into poverty due to kidney disease each year.1 ■ 1. Essue BM, Laba TL, Knaul FM, Chu A, Van Minh H, Phuong Nguyen TK, et al. Economic burden of chronic ill health and injuries for households in low and middle income countries. In: Jamison DT, Gelband H, Horton S, Jha P, Laxminarayan R, Mock CN, et al., editors. Disease control priorities. Volume 9. 3rd ed. Washington, DC: The World Bank; 2018. 2. Garcia-Garcia G, Jha V. Chronic kidney disease in disadvantaged populations. Indian J Nephrol. 2015 Mar-Apr;25(2):65–9. 3. Stanifer JW, Muiru A, Jafar TH, Patel UD. Chronic kidney disease in lowand middle-income countries. Nephrol Dial Transplant. 2016 06;31(6):868–74. 4. Bassi A, John O, Gallagher M, Kotwal S, Joshi R, Essue B, et al. Methodological challenges to collecting clinical and economic outcome data: lessons from the pilot dialysis outcomes India study. Nephrology (Carlton). 2018 Mar 23; (Forthcoming) 5. Senanayake SJJ, Gunawardena NS, Palihawadana P, Bandara S, Bandara P, Ranasinghe AU, et al. Outof-pocket expenditure in accessing healthcare services among Chronic Kidney Disease patients in Anuradhapura District. Ceylon Med J. 2017 06 30;62(2):100–3. 6. Jha V. Universal health coverage for dialysis in India – first steps towards change. In: The Lancet Kidney Campaign. New York: Elsevier; 2018. 7. Knight J, Perkovic V. The affordable dialysis prize steams ahead. Lancet. 2016 Mar 12;387(10023):1040. 8. George C, Mogueo A, Okpechi I, EchouffoTcheugui JB, Kengne AP. Chronic kidney disease in low-income to middle-income countries: the case for increased screening. BMJ Glob Health. 2017 05 29;2(2):e000256. 9. CKD patients to get 2,500 as pension. The Hindu. 2017 Sep 2. 10. Nugent RA, Fathima SF, Feigl AB, Chyung D. The burden of chronic kidney disease on developing nations: a 21st century challenge in global health. Nephron Clin Pract. 2011;118(3):c269–77. Universal health coverage and chronic kidney disease in India Beverley M Essue, Vivekanand Jha, Oommen John, John Knight & Stephen Jan


We report a patient with advanced idiopathic pulmonary fibrosis (IPF), who in a single presentation experienced three complications of the disease: an acute exacerbation, spontaneous pneumomediastinum, and platypnoea‐orthodeoxia syndrome. Despite there being no definitive evidence‐based treatment for an acute exacerbation, we report a marked improvement with high‐dose steroids. This case also highlights the importance in IPF patients of considering pneumomediastinum as a cause of non‐cardiac chest pain, as well as platypnoea‐orthodeoxia in those with positional dyspnoea.


Consultation of the DfE's Green Paper, Support and Aspiration: A New Approach to Special Educational Needs, provoked considerable debate among public and private sector professionals, parents and young people over the planned special educational needs reform. Since then, publication of the Children and Families Bill in 2013 indicates definitive changes in law, while the revised SEN Code of Practice, which will provide professional guidance, is awaited. There are implications to this reform beyond those which have already been published, although alluded to in the Green Paper. This article will explore the influence of language in the deconstruction of disability, the implications of raising the threshold before a categorisation of SEN applies, concerns arising from implementation of the Single Assessment Process and, finally, how funding reforms will negate some of the anticipated benefits for parents and their children. [ABSTRACT FROM AUTHOR]


This review aims to explore the HawkOne atherectomy (Medtronic), a single use directional atherectomy device, explaining in depth its indication, selection, preparation and application. It further provides techniques and tips to troubleshoot the device upon its use. Further, a review of the current evidence for directional atherectomy in the infra-inguinal arteries is conducted. Identifying that directional atherectomy in the infra-inguinal arteries allow for significant plaque modification and lumen gain without the use of barotrauma from balloon angioplasty. Highlighting that directional atherectomy had a lower incidence of flow limiting dissections and need for stenting after such treatment.


Utilities must trim trees in order to furnish reliable electric service and minimize the danger to their customers. In a perfect situation, this would include removing all trees near utility lines and replacing them with compatible tree species. Union Electric has established a corporate program, UE Greenleaf, to offer alternatives to communities that express interest in removal and replacement programs or other reforestation projects.


We demonstrate direct excitation and broadband guidance of polarization vector beams (PVBs) in commercially stock-available small-core ultrahigh-NA optical fibers. A simple numerical analysis supports the experimental results and provides criteria for stable guidance of PVBs.


In 21st Century New Zealand, there are around twenty-five annual festivals that celebrate diasporic Pacific peoples and cultures. This paper addresses the Pacific festival space, and how it can be seen as a highly public event through which both the roots and routes of diaspora are displayed and performed. I argue that festival performances illuminate the various routes that connect Pacific peoples to ancestral roots. Simultaneously, they also create a rooted-ness within New Zealand, highlighting fluidity in diasporic flow, and creating multi-local senses of 'home'. To contextualise this argument, these two concepts are situated within a Pacific diaspora framework and by using the concept of music as a territorialising process. It is here that popular music plays a particular role. As an art-form that represents the twenty-first century reality of Pacific peoples in New Zealand, popular music allows for the performance and assertion of these twin notions of belonging within the same time-space.


This work shows the results of a research carried out in secondary school and university developing a co-disciplinary Research and Study Course (RSC) on questions connected to Physics and Mathematics in different groups. We present preliminary results of the RSC developed in three different groups: science education researchers, N=25 Mathematics teacher students (training teachers of Mathematics) at University, and N= 68 secondary school students. The development and scope of the RSC in each group is described by using the RSC components as defined by Chevallard's Anthropological Theory of Didactics (ATD). Furthermore, a short description of the Praxeological Model of Reference is presented. This model was built by the researchers group in order to reply to the generative question, unknown in the beginning, and to anticipate and to conceive the evolution of the possible SRC in each institution. Some general results in each group are discussed and some conclusions concerning the ecology of the pedagogy of research and questioning the world at university and secondary schools are drawn.


CV. Bintang Ternak Hessa Air Genting is one of the livestock companies engaged in the distribution and warehouse of chicken egg products, which is located in Hessa Air Genting Village, Asahan Regency. Based on the results of research and interviews conducted by researchers at CV. Bintang Ternak Hessa Air Genting, a problem that often occurs in the company is that there is often a shortage or accumulation of chicken egg products to be marketed, not in accordance with the number of requests from consumers. The purpose of this study is to apply the Trend Moment method to predict the number of Chicken Egg Demand in CV. Cattle Star Hessa Air Genting in the next few months based on the type of egg, namely A+, A, B, C, D, and E


There have been different comments on the Turmoil the Five Northern Minorities Caused in Central China and the Reform of Emperor Xiaowendi in the history textbooks in Late Qing dynasty and the period of the Republic of China.The general opinion in Late Qing dynasty is that the Turmoil had brought disaster to China and the Reform was the cause of the decline of Northern Wei dynasty.After the foundation of Republic of China,however,people tended to think that,though the Turmoil had brought disaster to central China,these northern minorities finally merged into Han nationality,and accelerated the development of Chinese nation.Since the 1930s,scholars began to pay more attention to the significance of these northern minorities in the formation of the Chinese nation and the development of Chinese culture,believing that all these nationalities merge together to form a new Chinese nation.This change of opinion actually reflects the process during which the Chinese nation develops its cognitive pattern,adjusts its narrative strategies in order to construct a general national identity.


1 The effects of clonidine, yohimbine, corynanthine and prazosin on glucose‐induced insulin secretion by incubated or perifused mouse pancreatic islets were investigated. 2 Clonidine (0.1 μm) inhibited glucose‐induced insulin secretion alone and in the presence of yohimbine (0.1 μm), corynanthine (10 μm) or prazosin (1 μm). 3 In higher concentrations, yohimbine (1–10 μm) antagonized the inhibitory effect of clonidine (0.1 μm) upon glucose‐induced insulin secretion by incubated islets and by perifused islets. 4 The results support the view that adrenergic inhibition of insulin secretion is mediated by α2‐adrenoceptors on pancreatic β‐cells.


Hysteresis in wages is modelled, and a tractable earnings function is derived. Estimation using a recent cross-section of UK data provides support for this function, which also outperforms rival specifications on the basis of goodness of fit


What makes Fryderyk Chopin (1810-1849), one of the most revered and loved composers in the piano repertoire, and is he truly a unique figure? This question has driven me for most of my musical life, resulting in my current research. This project emerged from my fascination with the wealth of forgotten composers and their music, which seemed all so familiar - was Chopin influenced by them to a degree that was never documented or questioned before? While Szymanowska's influence has been noted before, the haptic considerations that led this process of influence have not been investigated. Using my experience as a pianist, I approached this question through a haptic lens. This thesis is divided into an Introduction, which addresses my motivation, Chapter 1, which refers to the historiographical and musical background of Chopin's formative years, the practice-as research approach to the methodology, and the literature review. Chapter 2 focuses primarily on two composers: Maria Agata Szymanowska (1789–1831) and Joseph Christoph Kessler (1800-1871). I compare their preludes and etudes, through a haptic perspective, with the preludes and etudes of Chopin. The influence of Szymanowska and Kessler on Chopin is demonstrated, through the presence of clearly identifiable haptic characteristics. The musical examples are integrated with video clips that demonstrate the haptic connections, in each case, at the piano. The last section of the thesis discusses my reflection and conclusion that Chopin was indeed influenced by these composers, especially through the haptic process. Although Chopin later developed his style beyond the formative influence of Kessler and Syzmanowska, I believe his music, and his approach to piano writing, owes a substantial debt to these two lesser-known composers, and that this connection can only be truly identified through the investigation of haptic considerations.


Train aerodynamics problem must be solved with the development of high-speed railway around the world, and the drag directly affects the maximum running speed of high-speed train. This paper established the numerical calculation model for single train passing through the tunnel with the real configuration of a domestic EMU with eight carriages. The formation mechanism and variation characteristics of the drag over time were analyzed. The drag value and the distribution characteristic of the individual parts were studied at different times of the train passing through the tunnel. The maximum and minimum drag values of the tunnel were compared with the drag of the open air condition. Results indicate the Mach wave directly affected on the pressure drag, the aerodynamic drag distribution of the whole train is changed over time and the fluctuation range of the pressure drag is larger than the friction resistance when the train passing through the tunnel. The maximum value and minimum value of total drag when the train passes through the tunnel are 1.95 times and 0.88 times of that in the open air. When the train is running in the open air, the pressure drag and frictional drag accounted for 61% and 39% respectively of the total aerodynamic drag.


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Background While aza is the only drug shown to prolong survival in MDS, only half of aza-treated pts achieve objective responses (10-20% complete remission), and 4-6 months might be needed before a response is seen. Therefore the ability to select pts with high and low likelihoods of benefit from aza therapy is a clinical and a research priority. No clinical or laboratory parameter consistently predicts response or survival with aza therapy. A French prognostic scoring system (FPSS) was proposed to predict survival among aza-treated pts with HR-MDS. We sought to compare the relative prognostic discriminatory power of the FPSS with that of the revised IPSS (IPSS-R) and the global MD Anderson prognostic scoring system (MDAPSS) in a large cohort of aza-treated pts with IPSS HR-MDS.

Methods The MDS database at Moffitt Cancer Center (MCC) was used to identify patients with HR-MDS (International Prognostic Scoring System [IPSS] intermediate-2 [INT-2] and high-risk) who received aza therapy. Kaplan-Meier curves were used to depict survivals, and the log-rank test was used to compare median overall survival (OS). Akaike information criteria (AIC) were used to assess the relative goodness of fit of the models.

Results We identified 259 patients HR-MDS (74.1% with INT-2 and 25.9% with high IPSS) treated with aza at the MCC. The median duration of follow up since diagnosis was 53 months (M) (95% confidence interval [CI], 49-59 M). The median number of aza cycles was 5 (range 1-72), with 75% of pts receiving 4 cycles of therapy or more. The median time from diagnosis to aza initiation was 1.5 M. The median OS for the entire cohort was 19 M (95%CI, 16-22 M), 64% of pts were males, 91% were white, 80% were older than 60 years, and 25% had therapy-related MDS. For the IPSS, the median OS was 23.5 M (CI, 18.4-28.6 M) for INT-2 and 15.9 M (CI, 13.6-18.2 M) for high-risk group (P=0.004). For the FPSS, the median OS was 29.5 M (CI, 14.1-44.9 M) for low risk (LR), 21.1 M (CI, 16.4-26.0 M) for intermediate risk (IR), and 14.1 M (CI, 8.7-19.5 M) for HR (P=0.001). For the MDAPSS the median OS was not reached (NR) for low, 53.5 M (CI, 37.5-69.4 M) for INT-1, 29.5 M (CI, 18.3-40.6 M) for INT-2, and 16.1 M (CI, 14.5-17.7 M) for high risk groups (P<0.0001). For the IPSS-R, the median OS 40.6 M (CI, 22.8-58.4 M) for low, 44.7 M (CI, 25.0-64.4 M) for INT, 23.5 M (CI, 20.3-26.8 M) for high, and 15.2 M (CI, 13.7-16.8 M) for very-high risk groups (P<0.0001). Scores generated using AIC to assess the relative goodness of fit (lower is better) were 1453 (IPSS-R), 1480 (MDAPSS), 1512 (FPSS), and 1522 (IPSS). The IPSS could not refine any of the other models. All three newer models refined IPSS INT-2 but not IPSS high-risk. The IPSS did not refine any of the newer models. The MDAPSS refined the FPSS LR and IR and the IPSS-R high and very-high groups. The FPSS refined IPSS-R very high risk group but not the not the MDAPSS. The R-IPSS did not refine the MDAPSS or the FPSS. Response rates were not statically significantly different within the prognostic groups in any of the scoring systems.

Conclusions The IPSS-R, MDAPSS, and the FPSS all functioned well to separate aza-treated pts with IPSS HR-MDS into prognostic groups with different survivals, but the IPSS-R and MDAPSS appear superior to the FPSS. None of the prognostic systems predicted response to aza therapy. HR-MDS patients with poor projected survival with aza therapy might be considered for experimental approaches.

Disclosures: Off Label Use: entinostat for MDS. Lancet: Celgene: Research Funding. List: Celgene: Research Funding. Komrokji: Celgene: Research Funding, Speakers Bureau.

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Objective To observe the effect of superoxide dismutase(SOD) compound on bacterial ulceration in rabbit's eyes and explore its mechanism.Methods Amikacin and SOD compound etc.were added to agar inoculating PS.Pyocyaneus and the diameter of inhabiting circles were measured.The rabbit model of bacterial corneal ulcer was created and then treated with amikacin.SOD compound was used as an adjunctive treatment while inactive SOD compound as a control.The clinical manefestation and its pathological change were observed and the amlonyldialdehyde (MDA) in the ulcer was assayed.Results In vitro experiment indicated that SOD compound had no anti bacterial effect.In rabbit corneal ulcer treated with SOD compound,the clinical manefestation and pathological change was slighter,the MDA was lower.Conclusion In rabbit's corneal ulceration,free radical and lipid peroxidation take part in the tissue damage.SOD compound can contradict this effect through eliminating excessive free radical and anti lipid peroxidation.Therefore,SOD compound has protective effect on corneal physiology and histological structure in bacterial corneal ulceration.


To investigate the distribution of oxygen in the pulmonary microcirculation in vivo, we developed a murine model of pulmonary intravital microscopy combined with multispectral imaging of hemoglobin saturation (SO2). A circular window(D 7‐10μm) was surgically excised from the right thoracic wall for microscopic access to the surface of the upper right lobe of the lung. Removal of intrathoracic air via a transdiaphragmal intrapleural catheter coupled the lung surface to the window membrane. An intravital microscope was modified for epiillumination by a light guide from a monochromatizing device (Till Photonics). Mice were ventilated at 60 breath/min and images were acquired during the expiratory plateau phases. Stacks of images at preselected wavelength ranges and exposure times were analyzed with a dedicated software (SO2 Analysis Program, SOAP) to obtain 2D SO2 images of the observed area. On SO2 images, arterioles, venules and capillaries could be distinguished clearly. Results show an increase in oxygen saturation from 70% to 100% during the passage from arterioles to capillaries over a vessel length of about 200μm.


The factors that relate to emotional intelligence and performance of food crop agriculture extension in the agricultural extension central, fisheries and forestry in Lambuya Subdistrict, Konawe Regency". The research objectives to know the level of intelligence food crop agriculture extension, and to know the factors that relate to emotional intelligence with the performance of food crop agriculture extension in the agricultural extension central, fisheries and forestry (BP3K) Lambuya Subdistrict, Konawe Regency. The achievement of research objectives done by taking two variables namely emotional intelligence variable which includes: (to know self emotional, managing emotions and to motivate themselves, to identify emotions in others, developing relationships with others) and performance of field agriculture extension which includes: (the quality and quantity of work, the knowledge and job skills, creativity, cooperation, and initiative). The sampling is done by using saturated (census) method sampling. The emotional intelligence level and performance of extension can be determined by using the interval equation. Whereas to know the relationship emotional intelligence and performance of Food Crop Agriculture Extension used rank Spearman correlation analysis. The research result shows that there is a factor that relates to emotional intelligence and performance of food crop agriculture extension which includes: developing self-relationships classified always with the percentage (42, 85%), have a significant relationship to performance of food crop agriculture extension whereas to know emotions, managing emotions variable, motivate self and to identify emotion in others, did not have a significant relationship .


Separation between primary and secondary lymphoid organs is a universal feature in jawed vertebrates. Strikingly, oncostatin M (OM)-transgenic mice present massive extrathymic T cell development, localized exclusively in the lymph nodes (LN). According to the prevailing paradigm, the thymus is the main source of T lymphocytes in gnathostomes mainly because thymic epithelial cells have a unique ability to support early steps in T cell development. It is therefore remarkable that productive T cell development occurs in the OM (cid:1) LN, despite the absence of epithelial cells. The present study shows that in the OM (cid:1) LN: 1) MHC class I expression strictly on hemopoietic cells is sufficient to support the development of a diversified repertoire of CD8 T cells; 2) the efficiency of positive selection of specific TCR-transgenic T cells is not the same as in the thymus; 3) negative selection is very effective, despite the lack of an organized thymic-like medulla. Furthermore, our data suggest that extrathymic T lymphocytes developing in the OM (cid:1) LN undergo extensive postselection expansion because they live in the microenvironment in which they were positively selected. This work illustrates how the division of labor between primary and secondary lymphoid organs influences the repertoire and homeostasis of T lymphocytes. The Journal of Immunology, 2002, 169: 684–692. he central peripheral negative selection


Background and Aims: Pulmonary Hypertension (PH) represents an aetiologically and clinically heterogeneous disorder accompanied by a severely impaired prognosis. Key steps of PH pathogenesis are vascular and right ventricular myocardial remodelling entailing the re-occurrence of fetal variants of the cell adhesion modulating protein fibronectin (Fn) being virtually absent in healthy adult tissues. These variants are liberated into circulation and are therefore qualified as excellent novel serum biomarkers. Moreover, these molecules might serve as promising therapeutic targets. The current study was aimed at quantifying the serum levels of two functionally important fetal Fn variants (ED-A+ and ED-B+ Fn) in patients suffering from PH due to different aetiologies compared to healthy controls. Methods: Serum levels of ED-A+ and ED-B+ Fn were quantified using novel ELISA protocols established and validated in our group in 80 PH patients and 40 controls. Results were analysed with respect to clinical, laboratory, echocardiographic and functional parameters. Results: Serum levels of ED-A+ Fn (p = 0.001) but not ED-B+ Fn (p = 0.722) were significantly increased in PH patients compared to healthy controls. Thus, the following analyses were performed only for ED-A+ Fn. When dividing PH patients into different aetiological groups according to current ESC guidelines, the increase in ED-A+ Fn in PH patients compared to controls remained significant for group 1 (p = 0.032), 2 (p = 0.007) and 3 (p = 0.001) but not for group 4 (p = 0.156). Correlation analysis revealed a significant relation between ED-A+ Fn and brain natriuretic peptide (BNP) (r = 0.310; p = 0.002), six minutes' walk test (r = −0.275; p = 0.02) and systolic pulmonary artery pressure (PAPsys) (r = 0.364; p < 0.001). By logistic regression analysis (backward elimination WALD) including a variety of potentially relevant patients' characteristics, only chronic kidney disease (CKD) (OR: 8.866; CI: 1.779–44.187; p = 0.008), C reactive protein (CRP) (OR: 1.194; CI: 1.011–1.410; p = 0.037) and ED-A+ Fn (OR: 1.045; CI: 1.011–1.080; p = 0.009) could be identified as independent predictors of the presence of PH. Conclusions: Against the background of our results, ED-A+ Fn could serve as a promising novel biomarker of PH with potential value for initial diagnosis and aetiological differentiation. Moreover, it might contribute to more precise risk stratification of PH patients. Beyond that, the future role of ED-A+ Fn as a therapeutic target has to be evaluated in further studies.


The purpose of this study is to measure the octave sound pressure levels and vibrations of a stanopod lathe. A theoretical analysis of the sound pressure levels near the osteoprosche machines has been performed. The results of measurements are given. It is obtained that the levels of sound pressure at the workplace exceed sanitary standards. This suggests that the increased noise levels are due to the impact of the sound radiation of the cutting tool and the axis being machined.


Argument mining is a core technology for enabling argument search in large corpora. However, most current approaches fall short when applied to heterogeneous texts. In this paper, we present an argument retrieval system capable of retrieving sentential arguments for any given controversial topic. By analyzing the highest-ranked results extracted from Web sources, we found that our system covers 89% of arguments found in expert-curated lists of arguments from an online debate portal, and also identifies additional valid arguments.


It is common nowadays to hear people speak of Management by Objectives. But it is not so common to hear the relevant but often ignored question, 'By whose objectives?' If the question were asked someone designing an effective 'management' learning programme, the answer should be loud and clear as 'by the learner's objectives.' This is so because the objectives of the learner are in full control of what is learned, how fast it is learned, how well it is learned, and for how long it stays learned. That is, the learner makes the choice of what is learned and/or unlearned, he learns what impresses him most (whether he is expected to learn such things or not) and leaves out the experiences that do not impress him at all (whether they are 'important' or not). This assertion of conscious will on the behaviour of the adult human being makes it imperative that for any learning programme to be effective, the learning material to be presented to the adult, must be made to be as near as possible to what he would have freely chosen (to satisfy his learning needs — why want to learn) in terms of content (what to learn with), methodology(ies) (how to learn), time (when to learn), duration (for how long to learn formally, location (where to learn), and facilitators (people to help him learn). Hence the need for a designer to put all these items together optimally for effective learning.


The management of mastectomy in breast cancer patients undergoes changes in the state of body shape and structure and reduces the function and potential of the body in the breast. The condition of breast cancer patients with advanced stages is considered as a terminal condition, one of the health services that is considered important is spiritual care. This study aims to determine the relationship between breast cancer self-image and spiritual response. This research method uses descriptive correlation, using a cross sectional approach. Population and sample, namely breast cancer patients in Waled District Hospital, using accidental sampling technique, obtained 42 respondents. The data collection technique used a Likert scale questionnaire. The self-image questionnaire with reliability of 0.958, and the spiritual response questionnaire is SPNQ (Spiritual Needs Questionnaire) with reliability of 0.714, and data analysis using the Spearman Rank test with a significance value of =0.05. Self-image in breast cancer patients stated that positive self-image as many as 37 people (88.1%) and high spiritual response as many as 39 people (92.9%). Spearman rank test results P-value 0.006 <α then H0 = rejected, meaning that there is a moderate and positive relationship between self-image and spiritual response in breast cancer patients at Waled Hospital, Cirebon Regency.


An extension of the periodic Anderson model by considering the finite f-band width is considered. A variational method is used to study the temperature dependence of the valence n f and of the magnetic susceptibility X s for various values of f-band width. As the f-band width is reduced, the low temperature peak in the susceptibility X s gets sharpened.


Pyridazine (1a), pyrazine (1b), pyrimidine (1c) and 1,4-dimethylpiperazine (1d) were quaternized at N-1 with alkyl iodides and polyfluoroalkyl halides under either neat or solvent conditions at 10-110 °C to form N 1 CH 2 CH 2 C m F 2 m + 1 (m = 0, 1, 6, 10) diazinium iodides, and N 1 CH 2 CH 2 F diazinium bromides in moderate to excellent isolated yields. Metathesis of these alkyl and monopolyfluoroalkyl substituted diazinium halides with other salts led to the formation of new quaternary compounds, some of which fall into the ionic liquid class (mp <100 °C), where [N 1 (R f CH 2 CH 2 ) + ]Y (Y = NTf 2 , PF 6 , OTf, NO 3 , ClO 4 ). 1,4-Dimethylpiperazine with 2.5 equivalents of I -bromo-2-fluoroethane in DMSO gave the diquaternized N 1 , N 4 -(CH 2 CH 2 F) 2 product. All compounds were characterized by 1 H, 1 3 C, 1 9 F NMR, MS, elemental analyses, and density measurements (for liquids). The phase transition and decomposition temperatures of the quaternized compounds were determined by DSC.


The points of contact between copyright and the historian are three: first, historians, particularly biographers, are writers and their works are often commercially valuable; second, both as writers and educators, historians are concerned with the effect of copyright upon their freedom to use copyrighted materials; third, some historians have become interested in the subject of copyright itself as a reflection of complex political, economic, and social struggles. These concerns are background for a discussion of U.S. Public Law 94-553, "The Copyright Act of 1976," which is the first general revision of copyright law in the U.S. since 1909.