When asked to write this Foreword, I confess to having a very 'undeveloped understanding' of children's mathematical graphics as determined by the book title. Whilst children's pictures and drawings have always held a profound interest for me and many other early years educators, the rationale behind children's representations and creations has often eluded me and I have resorted, no doubt like many readers, to saying 'Tell me about your picture' in the hope of some elucidation of what I might do or say next to the child! Within a few pages of starting to read this book, I felt a certain 'guilt' that I could have done considerably more to understand the meanings behind children's playful representations especially in mathematics.


Rationale In my previous research, I conceptualised 'auditory distress' as a basis for analyzing the individual listener's position towards the auditory scene in a (music) theatre performance. This 'distress' in listening mainly manifests itself due to a conceptual radicalism in the use of sound on the stage in the exploration of semiotic excess (such as plethora, multimedia, split perception), which is often intensified by a lack of signifiers or a sensory/visual 'deprivation'. By studying how auditory distress is channelled through various listening perspectives in composition and performance, we can start to understand the necessity of the listener's responses through his modes of listening, specifically in relation to his individual listening capacities and the cultural norms and values predicated by contemporary aurality. However, this theoretical model does not yet encounter communal listening experiences, which include the translation and entangling of cultures. Therefore, I propose to extend the theory of aurality with a more historically and socially sensitive scope on the notion of community, which lays bare the cultural transactions and disjunctures that shape aurality today. The main aim of my current research is to pair sociological concepts with culturalist perspectives on identity issues – which I term a 'socio-aesthetic approach' – to identify issues that would be later tested against policy analysis and in-depth interviews. At the centre of my inquiry with the following paper, I critically reread Schafer's pivotal notion of the 'acoustic community' in soundscape theory through other, philosophical notions of community, such as Nancy's 'inoperative community', Agamben's 'the coming community' and Blanchot's 'unavowable community', among others. I aim to conceptualise how mixed audiences are much-contested sites of tension between listening cultures shaping the individual against the hegemony of norms, tastes and prejudices that surround formative definitions of community. Whereas R. Murray Schafer's timeworn notions of the 'acoustic community' and 'acoustic horizon' have still explanatory value in conceptualising the relation of individual listeners to the external world, particularly their sounding habitats and communal audio practices in multicultural situations, these notions are in need of revision to consider the social-aesthetic aspects of developments in audio design, sound/music dramaturgy, composition for the stage and its interpretation. 'Community' will therefore be explored philosophically as an open, critical and complex concept. Post-migrant theatre projects will be considered that address the representation of heterogeneous, interconnected communities through hybrid sound and music practices by challenging aurality as a space of contestation rather than homogenisation. The …


Abstract The title compound crystallizes in the triclinic space group PI with cell constants a = 6.534(6) b = 10.922(9), c = 14.905(7) A, α = 94.44(5) β = 94.69(7) and γ = 105.41(1)°, V= 1016.61 A3 and d(calc; Z = 2) = 1.778 g cm−3. A total of 3824 data were collected over the range of 4° ≤ 2 0 ≤ 50°; of these, 2994 were independent and had I ≥ 3σ(I); these were used in the solution and refinement of the structure. The final R(F) and Rw(F) residuals were 0.072 and 0.108, respectively. The molecule crystallizes with two half cations at inversion centres and the anion in a general position. The two independent Co-N(NO2) distances of the cations are 1.954(2) and 1.921 (2) A, respectively, while in the anion, they are 1.901 (2) and 1.901(2); the Co-N(—NO2) distances in the cation, being trans to another NO2, are noticeably longer than those in the anion which are trans to oxalato oxygens and thus, we observe a trans influence. The Col-N(NH2) distances in the cations are 1.956(2) and 1.948(2) A while those for...


Autophagy is a well-known process of cell death. In this work we show that it can be actived in cancerous cells at Quasi-Zero Gravity environments. The result is the total destruction of the cancerous cells without use of medicaments.


SUMMARY Salted duck eggs imported from Taiwan were examined for bacteria. The following organisms were isolated: Pseudomonas cepacia (a pathogen of emerging importance to public-health officials which is now under intensive study), Alcaligenes metalcaligenes, A. recti, Micrococcus luteus, Pasteurella hemolytica, and Ps. aeruginosa.


The combined effect of chirp and jitter is crucial when elaborating quantum random number generator (QRNG) based on the interference of laser pulses. The chirp is one of the sources of classical noise in the QRNG; therefore, its contribution should be reduced. Here, we consider in detail the interference of gain-switched semiconductor laser pulses affected by the chirp, jitter and relaxation oscillations. It is shown how to reduce the combined impact of chirp and jitter on the interference using a telecom bandpass filter. In addition, we derive a simple estimate of the applicability of the Gaussian approximation for the laser pulse shape. Experimental results are reproduced by Monte-Carlo simulations using a rigorous model based on the solution of laser rate equations.


A biochemical method is used to separate out human megacaryocyte auxin, a new growing factor of hematopoietic cell, from urine and serum of aplastic aneumia patient. By amino acid sequence analysis, the c DNA of said factor is cloned from cDNA library of human embryo's liver. Said factor can obviously promote the formation of bone marrow megacaryocyte colony and the generation of thrombocyte, and the growth of granulocyte and erythrocyte, so curing cytopenia and anemia.


Provided are a wireless communication device, a wireless communication system, and a wireless communication method, with which differences in transmission delays in multiple wireless lines can be suppressed. The wireless communication device (1) has a division means (12) and a transmission means (14). The transmission means (14) transmits radio waves via multiple wireless lines. The division means (12) generates multiple fragments by dividing data into sizes corresponding to the respective transmission capacities of the multiple wireless lines. Furthermore, the transmission means (14) transmits each of the multiple fragments to another wireless communication device via a wireless line having a transmission capacity corresponding to the size of the respective fragment.


Taking some basic project as an example,the paper analyzes the reasons for the large-scale concrete cracks,points out the controlling methods from the mix proportion of the concrete,concrete mixture,transportation,grouting,maintenance,and temperature measurement,and points out the reasonable construction procedure and construction measures should be arranged for the large-scale concrete construction,so as to ensure the construction quality.


In the wire-driven parallel suspension system, because manufacturing and assembling deviations exist, the expected control accuracy can not be reached. A mathematical model of wire-driven parallel manipulators is established. Effects of the deviations eliminated can improve the accuracy of the mathematical model. Particle swarm optimization (PSO) is a robust stochastic evolutionary computation technique, which is very easy to understand and implement. Particle swarm optimization is used to calculate model deviations and find values of the deviations. The results obtained by the particle swarm optimization algorithm can update the mathematical model of the wire-driven parallel manipulators and improve the control accuracy of the wire-driven suspension system.


Angela Youngman takes a look at some of the problems surrounding school dinners and finds out how some schools are tackling these issues in a bid to make meals more attractive to pupils and more profitable for the school.


"Feel-good film" has become one of the most widespread typologies in popular discourses on cinema in recent years. Although primarily North American in application, the "feel-good" label has been a...


The carbide behavior of a directionally solidified Co-base superalloy DZ40M has been investigated after creep at 700 degrees C and 900 degrees C. During the high temperature creep, a great amount of secondary carbide, M23C6 precipitated in alloy matrix. At 700 degrees C, the M23C6 precipitation occurred in slip bands, indicating that it was stress-induced, while at 900 degrees C, M23C6 formed surrounding the primary carbides, which is a characteristic of thermally aged alloy. The M23C6 particles pinned up dislocations and subgrain boundaries, strengthening the alloy matrix effectively. The creep crack initiation of DZ40M alloy was exclusively related to the primary carbides. The fracture of the primary carbide and the crack at the interface between them and matrix resulted in the crack formation. Furthermore, it was found that at 900 degrees C, the surface of specimens was oxidized severely and the preferentially oxidized primary carbides acted as crack initiation sites.


Benzisothiazolinone (BIT; CAS no. 2634‐33‐5) is used as a biocide in various products, including water‐based paints, metalworking fluids, and household products. In recent years, increasing sensitization rates have been observed in Europe.


Carbon monoxide (CO), a gaseous mediator produced by haem oxygenases (HOs), has been shown to prevent stress‐, ethanol‐, aspirin‐ and alendronate‐induced gastric damage; however, its role in gastric ulcer healing has not been fully elucidated. We investigated whether CO released from tricarbonyldichlororuthenium (II) dimer (CORM‐2) can affect gastric ulcer healing and determined the mechanisms involved in this healing action.


Taking the construction of Youth Street Station of Shenyang Metro as case history,the author presents the major construction steps and key points of PBA(Pile-Beam-Arch)construction method.Due to the complex structure of the Metro station,PBA(Pile-Beam-Arch)construction method is adopted,which improves the safety and stability of the works,minimizes the deformation occurring during construction and protects the adjacent structures and buildings effectively.


Problems Arising from the Definition Mis-diagnosis It will almost certainly be impossible to obtain information about all cancer patients, since there will be many in whom the disease is diagnosed otherwise. Obviously, if these patients die without post-mortem examination, these errors are unlikely to come to light. Again, many patients may be registered as having cancer who, in fact, have some other disease. Errors of this kind may be rectified because of the course taken by the disease or as a result of further investigations or by postmortem examination.


In this article,the importance of hard power and soft power of university library in the information age was discussed and the meaning,characteristics and the relationship between hard power and soft power of university library were pointed out.On the basis of analysis of factors affecting hard power and soft power,an index system adapted to requirements of the development was established.


Purpose - The purpose of this paper is to evaluate the performance of socially responsible funds by closely examining funds' investment styles. Design/methodology/approach - The authors apply William Sharpe's method of style analysis to evaluate the performance of 94 US socially responsible mutual funds. By using the fund style as a benchmark, the authors are able to separate the performance attributed to style and selection. Findings - The authors observe that underperformance of socially responsible funds is more pronounced and common than identified in the previous literature. Proponents of socially responsible investing argue that screening process provides an opportunity to fund managers to identify best companies in terms of future financial performance. The paper finds that active management of mutual funds is an important determinant of their performance in socially responsible investing industry. This paper provides evidence supporting that active management of socially responsible funds add value. Originality/value - This study will help investors in allocating their portfolios among many of the available SR funds. The result – actively managed SR funds outperform their passive counterparts – will be valuable for those investors who are willing to invest in socially responsible funds but are concerned about the financial performance.


We have studied the effect of the series resistance on the heating of the cathode, which is based on carbon nanotubes and serves to realize the field emission of electrons into the vacuum. The experiment was performed with the single multi-walled carbon nanotube (MCNT) that was separated from the array grown by CVD method with thin-film Ni-Ti catalyst (nickel 4 nm / Ti 10 nm). The heating of the cathode leads to the appearance of a current of the thermionic emission. The experimental voltage current characteristic exhibited the negative resistance region caused by thermal field emission. This current increases strongly with increasing voltage and contributes to the degradation of the cold emitter. The calculation of the temperature of the end of the cathode is made taking into account the effect of the phenomenon that warms up and cools the cathode. We have developed a method for processing of the emission volt-ampere characteristics of a cathode, which relies on a numerical calculation of the field emission current and the comparison of these calculations with experiments. The model of the volt-ampere characteristic takes into account the CNT's geometry, properties, its contact with the catalyst; heating and simultaneous implementation of the thermionic and field emission. The calculation made it possible to determine a number of important parameters, among which the voltage and current of the beginning of thermionic emission, the temperature distribution along the cathode, the resistance of the nanotube. The phenomenon of thermionic emission from CNT's was investigated experimentally and theoretically. The conditions of this type emission occurrence were defined. The results of the study could form the basis of theory of CNT emitter's degradation.


The High Luminosity Large Hadron Collider (HL-LHC) project will extend the discovery reach and the capability for precision measurements in particle physics. Its program is enabled by advances in accelerator and detector technology. The LHC accelerator complex will undergo successive upgrades until 2025. To meet the experimental challenges of the increased instantaneous luminosity of up to a factor 7 with respect to the design value, 1034cm−2 s−1, the ATLAS experiment will undergo a replacement of the tracker system to sustain and improve the performance of the present detector. Due to the reduced material budget and the high charge collection and tracking efficiency, thin n-in-p planar pixel modules are promising candidates to instrument parts of the new pixel system. Pixel modules assembled with 100 μm and 150 μm thick sensors are the focus of this thesis. They are characterised exploiting different methodologies. In particular, the charge collection and hit efficiencies are studied before and after irradiation up to the expected maximum fluence range in the HL-LHC of 1016 neq cm−2. Additionally, the transient current technique is used to investigate charge collection and electric field properties within the sensor depth of 100 μm and 150 μm thick sensors. In the course of this thesis, a study is performed on the effect of different geometries of the biasing structures, necessary to perform IV measurements of the sensors before the interconnection to the readout chip. Given the fact that these structures cause a decrease of the hit efficiency after irradiation, the best technological solutions are investigated with beam test campaigns. To maintain the present level of occupancy also at the high particle multiplicity of the HL-LHC, a new readout chip was developed with a chip cell size of 50×50 μm2, resulting in a higher granularity with respect to the present chip cell size of 50×250 μm2. Sensors compatible with the current readout chip but subdivided into smaller pixel cells of 50x50 μm2 size were designed and are characterised to make first predictions for the performance of small pixel cells in the HL-LHC environment.


Hydrography in the coastal waters of Bangladesh has never
 been an easy task for surveyors. Being situated in the deltaic region, the area
 is very dynamic. Siltation, shifting of channels, emergence of new islands and
 low tide elevations, etc. are very common phenomena. Apart from a few common
 deltaic conditions experienced elsewhere, there are a number of local conditions
 which are peculiar to this area only. The coastal water is exceptionally laden
 with sediments coming from upstream and therefore, turbidity is extremely high
 and degrades the performance of survey equipment. The Monsoon in the region
 causes extra rainfall and seasonal cyclones add another dimension to the
 complexity of the area. Salinity is not homogeneous and sea temperature through
 the water column varies from place to place. The professionalism, prudence and
 dedication of the Bangladesh Navy surveyors are key factors for successful
 hydrographic survey operations in the area.


Although Graves' disease and systemic sclerosis are both autoimmune disorders, their relationship is rarely reported. We present the case of a Filipino woman with goitre and thyrotoxic signs and symptoms. Diagnosed with Graves' disease at the outpatient clinic, she took antithyroid medications and underwent radioactive iodine ablation with resultant hypothyroidism after 6 months, during which she began to experience skin tightness over the face, neck and fingers. Workup revealed limited cutaneous systemic sclerosis, and the patient improved with methotrexate. This case highlights the increased prevalence of coincident autoimmune disorders in Graves' disease.


General Principles of Bracing Within recent years, reemphasis upon the rehabilitation of severely disabled individuals has "spotlighted" the importance of proper lilting braces in the teaching of ambulation and daily activities. There seem to be several points of view regarding the intelligent selection of braces for lower extre mities. One group holds that patients should be braced maximally as in dicated by a careful analysis of existing tests of muscle function. Followers of this plan contend that any excess braceage may be discarded as the patient's recovery and proficiency in handling his body improve. They assert that braces and other supportive apparratus can be an asset in teach ing control of body segments and in the functional training program. For example, they might say that the patient, hovering on the borderline be tween wearing a pelvic band and attempting activities without one, might do well to wear the pelvic band for a number of weeks to develop stability and the sensation of proper body alignment.


The Banking Sector Reforms  were initiated in India as part of the overall structured reforms aimed at improving the productivity and efficiency of the economy. The study is based on the secondary data retrieved from State Level Banking Committee Odisha. The scope of the study is limited to the analysis of performance of the Commercial Banks for the period 2000 to 2009. It examines CD Ratio, percentage of priority sector advance to total advance, overall of recovery position of bank's dues & the position of recovery under Government sponsored programme. The data has been analyzed by percentage method. The percentage of Priority Sector advance to total advance of Public Sector Banks in Odisha has always been greater than that of Private Sector. The overall performance of Public sector banks was found to be better than Private Sector banks. The main causes of NPA has been the directed loans system under which commercial banks are required to lend a prescribed percentage of their credit(40%) to priority sector.


The earthquake early warning (EEW) concept is getting increasingly prevalent and somewhat replacing the expectation for earthquake prediction. An extensive real-time monitoring and EEW system installed in a wide region can detect an earthquake within seconds, and immediately issue alerts to affected areas through public media. On-site EEW systems developed for specific facilities may also detect an event and enable the facilities to take necessary actions before strong hits. Having timely warnings come accurate, EEWs can mitigate economy losses and save many lives. However, there are issues regarding EEWs provided by a big network and on-site monitoring systems that specialists in seismology know clearly, for which the general public has to be educated. A big EEW system estimates seismic intensities using a conventional ground motion prediction equation (GMPE) as a function of distance that are not always in agreement with observed intensities. The actual intensity distributions in felt earthquakes show short-wavelength variation. The frequency band in which seismic intensities are determined is from about 0.5 to 10 Hz, and thus the response of subsurface structure is significant in the estimation. The ground motion at a specific site should be evaluated not only by a GMPE and a site amplification factor, but also accounting for the incident azimuth of incoming seismic waves. We have some exploratory studies to illustrate the local subsurface effects using data recorded by the dense network of strong motion instruments (with a station interval of less than 1.5 km) in Yokohama City. We used several small earthquakes of a similar magnitude (M~4.5) that are located at an epicentral distance of ~60 km from the network and provide different incident azimuths of incoming waves to the network. The observed ground motions at the stations show variations among the events reflecting 3D structural effects along the propagation paths. We also show the variation of amplification from a borehole to the surface using Kik-net data, and suggest that on-site calibrations are necessary for better intensity estimates. Should an earthquake occur directly beneath a crowded metropolitan area, e.g. Tokyo, the warning time is


As Otto A. L. Dieter argues in his landmark essay, "Stasis" (1959), Greek concepts of motion provided classical rhetoricians with a theoretical framework for analyzing and conducting rational argument.' The various ways in which motion can be considered contrary, the different "grounds" on which contrary motions come to "rest," the array of faults impeding contrary motions--all these distinctions, borrowed from the philosophic study of kinesis (movements) and metabolai (changes in Being), were applied by rhetoricians to describe and facilitate amphisbetesis, or the "moving apart" of opposing assertions. Stasis theory, then, provided a paradigm essential to the two phases of the rhetorical process: Noesis (Cogitation) and Poiesis (Production). This paradigm allowed the rhetorician to reflect upon--and upon reflection, to judge--whether a conflict of wills and a contest of assertions truly existed, and therefore, whether the matter under dispute was properly rhetorical. Likewise, the paradigm allowed him to anticipate the "question" to be resolved, the strategies of accusation or defense most likely to be adopted by the opponent, and consequently, the posture or strategy best suited to winning the dispute. If it is true that "theories of classical rhetoric have survived because of their utility," then stasis theory has proven indispensable: for over 2000 years it has survived within the canon of rhetorical theory.2 Its most recent incarnation has taken place during the past four decades. Motivated first by historical interest, rhetorical scholars are now reconstituting stasis theory for much the same reason that prompted its formalization in the second century B.C.: the need to find an overarching paradigm that shapes the vast array of distinctions belonging to rhetorical theory into a practical system, one capable of identifying and resolving current communication problems.3


OBJECTIVE: To compare the result of "casein phosphopeptide amorphous calcium phosphate" with "sodium fluoride" (900 ppm) in remineralization of enamel after orthodontic debonding. METHODOLOY: This study was performed on premolars. Teeth were distributed into 3 groups A, B and C. The baseline microhardness of samples was measured. To create artificial demineralization, all samples were dipped in demineralizing solution. Surface microhardness (SMH) was re-measured for demineralization. Then, CPP-ACP was applied on teeth of gp B and NaF (900 ppm) was applied on teeth of gp C for remineralization. All teeth were cycled between deionized water and surface treatment for 12 weeks. The SMH of gp B and gp C was re-measured for remineralization. Paired t-test and Independent t-test were practiced to match MH before and after demineralization while keeping P value < 0.05. One way ANOVA was practiced to match mean difference in baseline MH and after demineralization. RESULTS: The baseline SMH of enamel decrease after demineralization. After application of test materials, mean SMH increased by 230.2 VHN and 207.5 VHN respectively. The %age of SMHR reveal the recovery rate of 41.2% in CPP-ACP and 19.1% in NaF group. CONCLUSION: For treating post orthodontic demineralized lesions, a remineralizing cream having casein phosphopeptide stabilized amorphous calcium phosphate is useful with some mineral and aesthetic improvements. KEYWORDS: Casein Phosphopeptide Amorphous Calcium Phosphate (CPP-ACP), Sodium Fluoride (NaF), Surface Microhardness (SMH), Vickers Hardness Number (VHN), Rmineralization.


Background: A ballet dance routine places extreme functional demands on the musculoskeletal system and affects the motor behaviour of the dancers. An extreme ballet position places high stress on many segments of the dancer's body and can significantly influence the mobility of the lower limb joints. Objective: The aim of this study was to observe the differences in the gait pattern between ballet dancers and non-dancers. Methods: Thirteen professional ballet dancers (5 males, 8 females; age 24.1 ± 3.8 years; height 170.2 ± 8.5 cm; weight 58.3 ± 11.2 kg) participated in this research. We compared these subjects with twelve controls (3 males, 9 females; mean age 24.3 ± 2.75 years; height 173.3 ± 6.01 cm; weight 72.2 ± 12.73 kg). None of the participants had any history of serious musculoskeletal pathology or injury or surgery in the lower limbs. Control group had no ballet experience. Each participant performed five trials of the gait at self-selected walking speed. Kinematic data was obtained using the Vicon MX optoelectronic system. The observed data was processed in the Vicon Nexus and Vicon Polygon programmes and statistically evaluated in Statistica. Non-parametric test (Mann-Whitney U test, p < .05) was applied for comparing the dancers and the controls. Results: Significant differences (p < .05) were found in all lower limb joints. In the dancers, greater hip extension (–15.30 ± 3.31° vs. –12.95 ± 6.04°; p = .008) and hip abduction (–9.18 ± 5.89° vs. –6.08 ± 2.52°; p < .001) peaks together with increased pelvic tilt (3.33 ± 1.26° vs. 3.01 ± 1.46°; p = .020), pelvic obliquity (12.46 ± 3.05° vs. 10.34 ± 3.49°; p < .001) and pelvic rotation (14.29 ± 3.77° vs. 13.26 ± 4.91°; p = .029) were observed. Additionally, the dancers demonstrated greater knee flexion (65.67 ± 4.65° vs. 62.45 ± 5.24°; p = .002) and knee extension (3.80 ± 4.02° vs. –1.54 ± 5.65°; p < .001) peaks during the swing phase when compared to the controls. Decreased maximal ankle plantar flexion was observed during the loading response (–8.84 ± 3.74° vs. –10.50 ± 3.99°) and increased maximal ankle plantar flexion in terminal stance (–20.30 ± 4.93° vs. –17.00 ± 3.99°; p = .025) was observed for the dancers. Conclusion: The results confirm that long-term intensive ballet training affects the kinematic pattern of particular joints during gait performance. The findings suggest overloading in the lumbosacral region and dysfunction or weakness of several muscles in ballet dancers.


In order to study the rotating strongly coupled Bose-Einstein condensations(BEC), a holographic model defined in an AdS black hole that duals to a coupled two-component condensations in global $U(1)$ symmetry broken phase with intercomponent coupling $\eta$ and internal coherent coupling $\epsilon$ is proposed. By solving the dynamics of the model, we study the process of formation and also the crossover from fractional to integer vortex phases. With changing only $\eta$ from zero to a finite value, fractional vortex lattices undergo a transition from hexagon to square lattice and finally to vortex sheets. By continuing to turn on $\epsilon$, we find that two fractional vortices in different components constitute dimers, and when $\eta$ transcend a critical value, multi-dimer like hexamer or tetramer made up of two and three dimers appear. As $\epsilon$ keeps increasing, some dimers rotate to adjust themselves and then constitute the lattice of integer vortices. Under an initial conditions similar to an spinor BEC vortices dynamics experiment, the appearance of disordered turbulence is found in the process of fractional vortex generation, which matches the experimental observation. While in the formation process of integer vortices, the appearance of grooves is predicted.


Periprosthetic infection (PJI) is a serious complication of total knee arthroplasty (TKA). PJI due to Brucellosis is a very rare entity. In this report, we described the case of knee joint loosening after TKA in a 63-year-old female who arrived with complaints of a restricted range of motion, stiffness, and pain. The diagnosis was made based on clinical, radiological, and laboratory findings. She was treated with antibiotics and two-stage revision surgery. We also reviewed all similar cases in the English literature from the epidemiologic, diagnostic, and treatment aspects and brought suggestions for evaluations before TKA in endemic areas. Authors emphasize that Brucellosis must be considered among differential diagnoses for patients with PJI, especially in endemic areas. Serologic evaluations and long-term blood and joint aspirated fluid culture must be performed when the patient has a history of recurrent febrile illness, joint swelling, and exposure to animals or the consumption of unpasteurized dairy products. Early suspicion of Brucellosis improves the outcome and prevents medical staff from being infected. A double therapy with doxycycline and rifampin for 6 months and performing two-stage revision surgery is the treatment of choice.


Aim: This study aims to investigate cardiac structure and function in patients with asymptomatic primary hyperparathyroidism (pHPT) and if there is any relation to severity regarding serum levels of calcium (Ca) and parathyroid hormone. Methods and Results: We consecutively included 50 patients (mean age 62.9 +/- 11 years, 45 women) with clinically diagnosed pHPT. We prospectively recruited 50 healthy control subjects, matched for age and sex. Standard transthoracic echocardiographic examination was performed using the 4 standard views and structural parameters as well as left ventricular (LV) systolic and diastolic function was determined. Mean LV ejection fraction and atrioventricular plane displacement were on average normal and did not differ between patients and controls. However, pHPT patients had significantly greater LV mass (148 +/- 37 vs. 127 +/- 29 g, P = 0.002), LV end diastolic area (81 +/- 20 vs. 68 +/- 18 cm(2), p = 0.003), LV posterior wall diameter (8.9 +/- 1 vs. 8.1 +/- 1 min, P = 0.006), and LA size (21 +/- 3 vs. 19 +/- 2 mm, P < 0.001). A moderate to severe LV diastolic filling impairment was present in substantially more pHPT patients, compared with control subjects (36% vs. 4%, P < 0:001). Conclusion: Patients with asymptomatic pHPT showed LV structural changes and impaired LV diastolic function. (Less)


We investigated the relationship between odor codability and odor memory representation in three cultural groups: French, American, and Vietnamese. In a first experiment, we asked participants from the three cultures to identify twice a set of 40 common odorants. From this task, we computed the codability of each of the 40 odorants. In a second experiment, we asked another group of participants from each culture to perform a yes/no recognition task on the same set of odorants. Results from Experiment 1 suggest that odor codability (1) is a meaningful dimension because some odors are more codable than others within a culture, (2) is equivalently measurable by several inter-and intrapersonal agreement indices, and (3) varies between cultures as a function of both the olfactory environment and language structure. Results from Experiment 2 show that the French codability scores predict recognition memory performance in all three cultures but that the American and Vietnamese codability scores predict none of the recognition performances.


To stratify the rate and prediction of lymph node involvement in prostate cancer patients undergoing sentinel‐lymphadenectomy depending on preoperative tumor characteristics, and to compare the outcome with the European Association of Urology Guideline indication for lymphadenectomy.


ABSTRACT The effect of Mo loading (10, 12, 15, 17 and 20 wt.%) on the physicochemical properties and reactivities of Mo(x)/ g-Al 2 O 3 sulfide catalysts for the conversion of 2-methoxyphenol at 573 K and 5 MPa of hydrogen pressure were studied. The catalysts were characterized by specific area (S BET ), electrophoretic migration (EM), X-ray photoelectron spectroscopy (XPS) and surface acidity techniques. The highest conversion observed for the catalyst with a Mo loading of 15 wt.% was attributed to an increase in the number of active sites due to highly dispersed Mo species. At higher Mo loadings, the formation of Mo aggregates led to lower guaiacol conversion. The differences in the phenol/catechol ratio were explained by the acid strengths of the sulfided catalysts. Keywords: hydrodeoxygenation, 2-methoxyphenol, MoS 2 , acid strength. 1. INTRODUCTION The increase in world energy demand during the 21 th century and the limited oil reserves, in part, have driven the industry to look for new and alternative energy sources. In this regard, biomass has generated considerable interests because of its renewability and its inertness with respect to CO


A general design methodology was presented for CFRP cylinder for deep ocean applications under external hydrostatic pressure.The formula method and FEA were comparable with the experimental results.


Abstract Objective: To provide an overview of vitamin and mineral intakes among children and adolescents in European countries and to present results from studies showing the impact of food fortification. Design: Comparative analysis of a number of nutritional studies among children and adolescents performed during the last decade in certain European countries. Setting: Spain, France, UK, North Ireland, Portugal, Germany. Subjects: Europeans aged 6 to 18. Results: Dietary surveys across Europe showed that varying levels of nutrient adequacy existed from one country to another, and that even within the same country, there were important nutritional gaps between different regions. In general, studies are difficult to compare, and information for many countries was missing. The results suggest that children and adolescents are the population group most likely to have higher risk of nutritional deficiencies, particularly for iron, vitamins C, E, B6 and folates. In France, Ireland, UK and Spain, food fortification, and particularly of breakfast cereals, has positively contributed to increasing vitamin and mineral intakes in childhood and adolescence. Conclusions: Information on vitamin and mineral intakes in European children is less available than in adults. Fortified foods may contribute to reducing nutrient inadequacy in European children and adolescents, but should not replace nutrition education.


We suggest a new possibility for ATLAS and CMS to explore the tt forward-backward asymmetry measured at the Tevatron, by attempting to reconstruct tt events, with one of the tops decaying semileptonically in the central region (|{eta}| 2.5). For several models which give comparable Tevatron signals, we study the charge asymmetry at the LHC as a function of cuts on |{eta}| and on the tt invariant mass, m{sub tt}. We show that there is an interesting complementarity between cuts on |{eta}| and m{sub tt} to suppress the dominant and symmetric gg{yields}tt rate, and different combinations of cuts enhance the distinguishing power between models. This complementarity is likely to hold in other new physics scenarios as well, which affect the tt cross section, so it motivates extending tt reconstruction to higher |{eta}|.


Invasiveness, resistance to treatment, and recurrence of gliomas are significant hurdles to successful treatment regimens. Data sets from Gene Expression Omnibus (GEO), CGGA-RNAseq, and The Cancer Genome Atlas Glioblastoma Multiforme (TCGA-GBM) were analyzed, and an increased expression of Cytochrome B Reductase 1 (CYBRD1) was identified and could be associated with aggravated clinical outcomes. Gene ontology (GO) enrichment analysis indicated that CYBRD1 co-expressed genes are enriched during an immune response. CYBRD1 overexpression in glioma cell lines is enhanced, whereas CYBRD1 silencing attenuated the aggressiveness of glioma cells. In IFN-α-treated glioma cells, IFN-α suppressed the viability and migratory ability and invasive ability of glioma cells, whereas CYBRD1 overexpression attenuated the antitumor effects of IFN-α. CYBRD1 could potentially serve as a biomarker for glioma recurrence. CYBRD1 overexpression enhances glioma cell aggressiveness and attenuates glioma cell response to IFN-α.


A liquid composition comprising an aqueous solvent, an enzyme with phosphatase, orthovanadate, mannitol and dithiothreitol, wherein the concentration of mannitol is between 1 mM and 100 mM, and the molar ratio of mannitol and orthovanadate is less than 1: 1.


ABSTRACT A modified solution is discussod of the continuity equation for minority carrier flow in junction transistors, obtained by adhering strictly to the space-charge neutrality approximation and applying alternative boundary conditions which differ from those usually taken principally in that a finite minority carrier density is permitted at the collector. An extension of the modified analysis to a.e. conditions is given, and a comparatively short working formula for the intrinsic short-circuit a.c. gain is determined as a function of operating point and frequency. The common-base cut-off frequency f αs evaluated, and the maximum in the variation of the f αwith emitter current, which has been observed experimentally, is associated with reduced d.c. emitter efficiency at high levels and is related to the corresponding fall-off in d.c. alpha. Experimental results are presented to show that, for a transistor with given cut-off frequency, both the electrical and metallurgical base widths are smaller than ...


Green jungle fowl (Gallus varius) is widespread in nature and community forests. This study aims to identify distribution patterns, habitat profiles, and the potential of green jungle fowl (GJF) as a source of biological learning based on a biocultural approach (biodiversity, cultural diversity, and language diversity). The case study was used for extensive bird exploration in a customary forest, Hutan Adat Bukit Demulih Bangli (HABD), from February to June 2022. Data on distribution patterns were collected with a combination of free-range, line transect, and point-count techniques and habitat profiles with physiognomy methodology. Meanwhile, document analysis and the concept map were used to demonstrate the potential of the GJF in HABD as a source of learning. The results revealed that GJF was unequally distributed, with a population at each observation point ranging from 2 to 10. The bird prefers forested areas dominated by shrubs with several trees and, therefore, has an open canopy that allows sunlight to reach the forested floor. Local knowledge and practices in the preservation of GJF and HABD are excellent resources for learning various biological materials and concepts in the context of biodiversity, culture, and language.


IDEF is a widely used methodology for traditional structured software development. As object-oriented softwares are widely used, an object-oriented version of IDEF, IDEF4, is developed. UML is de facto standard for object-oriented software development methods. Whereas IDEF is widely used for CALS/EC, UML is used for general object-oriented software development. Most software developers are not familiar with IDEF4 but familiar with UML. Moreover, UML has many CASE tools. So we can develop software efficiently if we convert IDEF4 model to UML model. In this paper, we transform IDEF4 models to UML models. We explain the rules and methods to convert IDEF4 model to UML model and applied the transform methods and rules to a case study.


Objective To summarize the clinical characteristics and surgical results of cerebellopontine angle meningiomas (CPAM), and to discuss microneurosurgical technique and skill in operation procedure in order to improve the tumor total resection rate and facial-vestibulocochlear nerve bundle preservation rate, and to reduce the mortality and morbility. Methods Thirty cases of CPAM treated microsurgically in our department in the last 10 years were analyzed retrospectively. Results Total resection of CPAM was achieved in 96.1% of the patients. The facial nerve was anatomically preserved in 96. 7% of all cases. The vestibulocochlear nerve was anatomically preserved in 80% of the cases. No patient died, two patients recurred. Conclusion Microsurgery is a safe and effective method for treatment of CAPM. Surgical skill and peri-operative management are the key points to improve the surgical result.


An embedded angle visual inspection system for line structured light was established based on DM642 to detect the angle of the line structured light in real-time accurately.Firstly,a device using the CCD as its image sensor was fixed on a datum plane,and the other one using a line structured laser as its light source was fixed on the plane to be measured.The image of the line structure laser on a screen was acquired by the CCD and its angular position value was obtained by on-line processing of DM642.The angle between the datum plane and the measured plane could be gotten through calibration of the angular position value.Then,the angleαbetween CCD surface and projection screen surface was proved to be the dominant error source by an error analysis.For compensating the error,a mathematical model was established.On the basis of the model,a calibration method was used as follows:the circular grating was used to control the laser generator to rotate accurately three angular displacements,and the angle value ofαand its direction were calculated according to the angular displacement value and the corresponding image detection,then the detection error brought by the angle could be compensated.The experimental results show that the angle error is reduced to 0.595% from 22.522% after compensation whenαis 0.331 97°and the measuring uncertainty of the system is 0.051 44°.


The experiments on rats with phetoplacental insufficiency induced by tetrachloromethane showed that beta2-mimetic salbutamol hemisuccinate (salgim) exhibits antioxidant activity. The effect was most pronounced in placenta, where salgim exceeded in activity the well-known reference drug essentiale.


We revisit the Flipping Coins (FCP) Problem and PennyAnte Game(PAG) and present a new method for solving them. In FCP and PAG, we consider the process where a string S is generated character by character randomly until certain fixed pattern occurs. FCP asks the expected length of the S while PAG asks the probability of occurrence for each pattern. The classical way (see [13]) of computing those statistic quantities was based on generating function(g-f) with elegant formulas for solving FCP and PAG. Suppose there are t patterns and their total length is L. It requires O(t+t·L) running time, in which O(t) is for solving t variables linear equations, and O(t · L) is for computing the coefficients. We give a more intuitive way to solve FCP and PAG. Our algorithm is based on the Markov-chain model, without using any g-f techniques. It combines several basic algorithms such as KMP and DFS, and its running time is also O(t + t · L). The accuracy of the answer is better then the previous method.


The article explains the need for a comprehensive integrated indicators generally characterize industrial, organizational and technological factors that determine the behavior of the production system AIC. One of these indicators may be organizational and technological reliability. Methodology for assessing organizational and technological processes reliability of agricultural production, which is understood as a comprehensive cumulative probability that achieve the desired result, developed by the entropy as a measure of uncertainty. Calculations of the parameters of the distribution of probabilities of system state "organizational and technological reliability of production" made the assumption of its similarity to the normal distribution of random variables. Accounting for Uncertainty based on entropy is a new concept to ensure organizational and technological reliability, allows us to determine the probability of production stability. It is concluded that the presented methodology allows to assess the reserves of the system and the amount of risk in terms of stability.


The consequences of flash floods can be dramatic in terms of casualties or economic losses. Jonkman (2005), in a global assessment of flood-related casualties, showed that flash floods lead to the highest mortality (number of fatalities divided by the number of affected people). For example, in the recent flash flood that occurred in the French Riviera around Cannes on 3 October 2015, 20 casualties and 650 billion euros of insured damage (source: http://www.ccr.fr/) were reported. Flash flood forecasting systems are critically needed to better organize crisis management and rescue operations.
As mentioned in chapter 1.3.4 (Gaume et al. 2016), flash floods are characterized by a rapid increase of river water levels. They often affect small watersheds, generally ungauged. The spatial and temporal variability of rainfall, landscape characteristics and pre-event catchment wetness are important influential factors in flash flood generation, contributing to the large space-time variability of hydrological responses (Borga et al. 2011).
Forecasting flash floods is therefore a complex task. It necessitates the monitoring of large areas, where each small watershed of a few square kilometres can possibly be affected. Real-time observation networks and models must run at small temporal and spatial scales, on the order of a few minutes and kilometres. Furthermore, discharge time series are not available for the majority of the possibly affected watersheds, posing a real challenge for model calibration and evaluation. In this context, radar based precipitation products and/or meteorological forecasts with a high resolution (typically 1 km2 grid size) are crucial (Creutin and Borga, 2003). Slight misplacements of the precipitation may for instance lead to
warnings attributed to the wrong river network and to inappropriate flood management decisions.


Observed sea surface temperature (SST) anomalies in the central eastern equatorial Pacific exhibit two kinds of phase evolution, that is, transition and no‐transition, for both the eastern Pacific (EP) and central Pacific (CP) El Niño events. The transition type of El Niño is characterized by a strong decay after its peak and followed by a rapid transition to a La Niña event in the subsequent winter, while the no‐transition type of both EP and CP El Niño is featured by a weaker decay after its mature phase and fails to develop a La Niña event in the decaying year. For the EP El Niño, the intensity of the anomalous easterly over the western equatorial Pacific in the transition type is stronger than that in the no‐transition type, which is likely determined by the coupling of the Indian Ocean dipole (IOD) during the developing phase and the Indian Ocean basin‐wide mode (IOBM) during the decaying phase. For the CP El Niño, larger differences of easterly wind anomalies between the transition type and no‐transition type are found over the central eastern equatorial Pacific during the decaying year, which is also likely related to the IOD and IOBM coupling process. In addition, the rapid decay of warm subsurface (80–160 m) temperature anomalies in the central eastern equatorial Pacific during the decaying phases is crucial for the phase transition for the two types of El Niño, together with the eastwards propagation of cold subsurface (100–200 m) temperature anomalies in the western equatorial Pacific. What is more, analyses of the mixed‐layer heat budget show that the phase evolution of the EP El Niño depends on dynamic forcing (zonal advection) due to the difference of anomalous mixed‐layer ocean currents, while the CP El Niño's different phase evolution is mainly caused by thermodynamic process, that is, net surface heat flux anomalies.


This study discusses about analysis of linguistic features of language expressions found in "Aime" column, Jawa Pos. The writer wants to find out the characteristic features and the purpose or the meaning of the usage such features in "Aime" column. In the analysis, the writer uses the descriptive qualitative approach. The writer takes certain articles of "Aime" column, March 2008 edition as the source of the data. Then, the writer uses four theories in analyzing the data such as Stylistic, Discourse, Semantic and Sociolinguistic. Finally, after analyzing the data, the writer has found the characteristic of "Aime", at first; "Aime" mostly uses Metaphor and Simile than other figure of speech. Second, the writer finds that beside Metaphor and Simile, "Aime" also mostly uses Simple sentence than other sentences (Compound and Complex sentence). Third, the writer finds that there are many informal languages instead of formal language. Fourth characteristic of "Aime" that the writer find is the domination of English code mixing and code switching. The last characteristic is the new invented terms that created by "Aime" which attracts the teenagers readers.


With the advent of the British in India, the colonial institutions were introduced throughout the country. In the Bahawalpur State, the Agency government stimulated the fiscal patterns of British India particularly its settlement policy, which brought amelioration in the native revenue system. This paper traces the historical process of land settlement for revenue generation and their impact over the agrarian economy of the State. These settlements became the major contributing factor towards the economic advancement. The different phases of settlement of land, along with the extent of government demand are established in this research. The third phase of land settlement resulted by the beginning of weir control water system, brought some revolutionary changes in the land pattern and revenue structure therefore, it has been particularly focused in this paper. The data for this study is mainly based on unpublished archival documents and unpublished assessment reports.


Recent advances in neuroscience have been hailed with enthusiasm by some educators, and treated with sceptical caution by others. Here I outline the potentially exciting applications of the state of the art to education, while acknowledging the rather limited contribution made by neuroscience to date. I argue that it is crucial for education to engage with neuroscience, so that an informed critical stance can be adopted to the different claims that are appearing about brain-based learning. Education as a discipline has been slow to take the initiative, creating a knowledge gap that is being filled by those actively marketing various educational programmes to teachers and schools on the basis of often spurious claims about the brain


At present Social media greatly enables people to participate in online activities such as Networking, tagging and commenting by using various sites. Twitter, Facebook, Linked In, etc are the major things people used to share information in any time and in any place. All the sites having the user information's like bio-data, area of interest like that and it gives recommendations based on that gathered knowledge. Recommender systems take a benefit of active and collective knowledge to make personalized recommendations to each user. It attempt to recommend items of interest to particular users based on their explicit and implicit preferences shown in collected survey. Basically, huge volume of information on the Internet generates a lot of problems for users of commercial websites and social networks; so that the competition between their owners in providing appropriate, sufficient and reliable information for their users has been stimulated. In this paper, identifying influential users of micro-blogging services and creating new user profile based on tweets around twitter are the problem statements taken for comparison. By the way a hybrid recommender system, based on trust with individual and group views is presented and Individual trust is calculated based on item points which are earned by users. Group trust regard to a particular method in clustering puts in one group the users who have similar tastes in selecting items.


Touchscreens utilize a menu-based interface. Menu-based interfaces are an easy and efficient practice that considers the users' physical and cognitive characteristics. However, the users' behavioral characteristics using touchscreens is quite different from that required in a typical desktop environment. Hence, in this study, an efficient menu-based interface for touchscreens was investigated. It considered different users' physical and cognitive characteristics in a touchscreen environment. A dynamic menu layout was found to be more efficient in both physical and cognitive aspects compared to static menu layouts. Additionally, the columnar structure in menus did not influence users' task-performance in touchscreen interfaces.


These contributors provide clear examples of how they involve students through literature, enable students to create new meanings through talk, and create and sustain learning communities.


Surgical experience in the last ten years (1-4) indicates that some strokes due to atheromatous obstruction of the internal carotid in the region of the bifurcation can be treated successfully by endarterectomy. About 15 per cent of all strokes fall in this category ( 5 ) . Since early diagnosis is the main factor for success in the surgical prevention of complete strokes, simple and safe diagnostic methods were sought. A history of transient ischemic attacks manifested by monocular blindness, hemiparesis, numbness or syncope obviously demands investigation for vascular lesions. Physical findings such as a bruit or the absence of internal carotid pulsation, though helpful, are not reliable. Retinal pressure measurements (6) are innocuous but frequently fail in the detection of carotid disease if there is sufficient compensatory blood flow through the circle of Willis. Angiography, though highly diagnostic, cannot be called a simple method for mass screening. Percutaneous carotid arteriography involves the dangers of subintimal injection of the dye, and dissecting hemorrhage or impingement of the lumen of the vessel by the needle with consequent prolonged ischemia. Repeated injections of highly concentrated iodinated compounds may damage the permeability of the blood-brain barrier. Advanced angiographic techniques such as the transbrachial retrograde method (7) greatly reduce the dangers. A reasonable surgical approach cannot be made without complete information about all four major cerebral vessels contributing to the total cerebral blood flow (CBF) . However, the number of angiograms can be substantially reduced by prescreening all stroke-prone patients with the carotid compression test (CCT) ; in this way, angiographic studies can be limited to those cases in which there is the probability of positive findings.


The invention discloses a composite silicone rein-ferrite-coating soft magnetic powder core and a preparation method thereof, and belongs to the metallurgical industry of magnetic functional material and powder. The soft magnetic powder core is formed by pressing and forming composite magnetic particles, wherein each composite magnetic particle comprises a soft magnetic metal particle and a composite insulation film, and each composite insulation film is coated on the surface of each soft magnetic metal particle. The preparation method of the soft magnetic powder core comprises the following steps of surface modification and coupling treatment of the soft magnetic metal particles, forming of the composite insulation coating around each soft magnetic metal particle, pressing and forming, and high-temperature heat treatment at 300 DEG C to 650 DEG C. Compared with the prior art, the soft magnetic powder core and the preparation method have the advantages that the adopted organic resin can resist the high temperature of 600 DEG C; since the soft magnetic ferrite power is added into the composite coating agent, the damage of the insulation layer to the magnetic performance of a substrate is reduced; and the magnetic conductivity is high, the density is high, the rapture strength is high, the loss is low, and the industrial production is easy.


There is a growing concern in counseling psychology that the field is not matching its commitment to social justice with adequate preparation of social change agents. Compiling and building off of a uniquely interdisciplinary framework, this article offers an alternative way forward for psychologists and trainees. Recommendations include a reorientation to institutions in which psychologists are immediately embedded and a legitimization of direct-action methods.


After a brief review of the nature of the solar corona, the X-ray output of solar flares is discussed in some detail with particular reference to emission line excitation mechanisms and to the information that can be obtained about the flare plasma from studies of the intensities, profiles and wavelengths of these lines. The X-ray crystal spectrometers on the NASA Solar Maximum Mission spacecraft are described and the interpretation of the spectra obtained with these instruments is discussed.


Eleven compounds were isolated from Pyrola.calliantha H.and their structures were identified as(4R)-4-dihydro-4-hydroxy-2,7-dimethylnaphthalen-1(2H)-one(1),(4S)-4-dihydro-4-hydroxy-2,7-dimethylnaphthalen-1(2H)-one(2),apocynin(3),gallic acid(4),3,4-dihydroxyhenzoic acid(5),pyrolin(6),5-(hydroxymethyl)-2-furfuraldehyde(7),hyperin(8),hyperin 3-O-(2″-galloyl)-β-D-galcopyranoside(9),Pyrolaside B(10),4-hydroxy-2,7-dimethyl-1-naphthalenyl-l-O-β-D-glucopyranoside(11).Among them,compounds 1,2,3,5,6,11 were obtained from the plant for the first time and compound 7 were isolated from the genus for the first time.


Engineered structures crossing active faults are vulnerable to damage during surface faulting earthquakes (e.g. Darfield 2010; Kaikoura 2016). The design and location of mitigation measures to counteract fault rupture requires detailed knowledge of the location of the active fault traces, fault geometry, including the width of the fault zone at the surface, and the distribution of strain within the fault zone. The current understanding of fault geometry and displacement profiles is based on predominantly subsurface data through essentially isotropic ground conditions. Although empirical relationships among fault parameters, such as rupture length, earthquake magnitude and average or maximum displacement, can be used to characterise potential surface rupture hazard for an entire fault zone, the behaviour of a fault at a specific location, as is required for engineering design, can be harder to forecast. For hazard planning and front-end engineering design, rupture zonation is a useful approach (e.g., NZ Ministry for the Environment; California's Alquist-Priolo Zonation maps). To produce meaningful fault rupture zonation maps requires an integration of data on tectonic geomorphology, paleoseismology, and both crustal and near-surface fault geometry. Rather than define narrow prescriptive fault avoidance zones, a better approach is to develop a broader zonation that highlight areas where there is the need for detailed fault rupture mitigation studies to be performed for all significant developments.


Chan and colleagues in their paper titled "Human origins in a southern African palaeo-wetland and first migrations" (https://www.nature.com/articles/s41586-019-1714-1) report 198 novel whole mitochondrial DNA (mtDNA) sequences and infer that 'anatomically modern humans' originated in the Makgadikgadi–Okavango palaeo-wetland of southern Africa around 200 thousand years ago. This claim relies on weakly informative data. In addition to flawed logic and questionable assumptions, the authors surprisingly disregard recent evidence and debate on human origins in Africa. As a result, the emphatic and high profile conclusions of the paper are unjustified.


The article is a comparative analysis of the economic vocabulary given in the registers of the Ukrainian language dictionaries in 11 volumes and 20 volumes, the diachronic aspects of its development and changes
that took place in it for the post-Soviet period.


PURPOSE: To obtain the subject inhibitory factor such as a leukemic cell proliferation inhibitor, a diagnostic drug or the like, which is purified through chromatography using an anion-exchange column, a lectin affinity column, a cation-exchange column, a reverse phase HPLC column, or the like. CONSTITUTION: Krebs II tumor cells are injected intraperitoneally to a mouse, and seven days later, the peritoneal fluid is extracted and centrifuged to collect cells. The cells are suspended in a medium and incubated in an atmosphere containing 10% CO 2 at 37°C for 24 hours, then introduced into a buffer solution containing 1 mM phenylmethyl sulfonyl fluoride, sodium azide and a surfactant and concentrated on a membrane. Subsequently, this concentrate is subjected to anion-exchange column chromatography, mouse leukemia-inhibitory factor(LIF) is eluted with an NaCl upgrade gradient, the eluted matter is successively subjected to mannose-affinitive lectin affinity column chromatography, cation- exchange column chromatography and reversed phase HPLC column chromatography to obtain the objective separated and purified LIF represented by the formula. COPYRIGHT: (C)1995,JPO


The article deals with key problems and contradictions of training of university graduates for the tourism and hospitality industry in Russia, primarily associated with the setting of educational goals. The article formulates the discussion points related to the updating of the existing educational standards for the enlarged "Service and Tourism" group. A systematic approach to the formulation of goals of higher education in the sphere of service and tourism is introduced. It features the designing of a multi-level system of both invariant and variable targets. The proposed approach generalizes the best domestic and foreign practice of training for the industry; in setting the objectives of the industry development trends it allows to take into account issues in the global and regional scale, the labor market requirements of specific businesses of tourism and hospitality industry, the specifics and possibilities of an educational institution and individual characteristics of future specialist, to induce him to self-design his professional career; improve the quality of higher education. Article submissions may be used for the improvement of higher education for the tourism and hospitality industry, the establishment of productive cooperation of the educational organizations and enterprises in the sphere of tourism and hospitality.


Abstract Aim: To investigate entheseal abnormalities by using Leeds Enthesitis Index (LEI) score in Psoriatic arthritis (PsA). Also, to find the correlation of LEI score and parameters of the activities of the cutaneous disease at baseline and after 6 months of treatment in PsA. Furthermore, to find correlation between LEI score and C-reactive protein (CRP) and Psoriasis Area and Severity Index (PASI) score as well as acute phase reactants. Materials and Methods: A total of thirty-nine patients with PsA and thirty-five age and sex matched healthy subjects were recruited. Clinical and laboratory assessment of disease activity included LEI score, PASI score, erythrocyte sedimentation rate (ESR) and CRP and were measured at baseline and after 6 months of treatment. Results: Enthesopathy showed a significant prevalence among PsA of 20.5%. We found a highly significant decreased in LEI score, PASI score, ESR and CRP at baseline compared to results after 6 months of treatment in PsA. A significant correlation between PASI score and LEI score was found. Also, PASI score was significant correlated with ESR and CRP in PsA. Conclusion: Enthesopathy showed a significant prevalence among PsA. The good potential parameters for PsA were LEI score, PASI score, ESR and CRP in PsA. Also, they may be the predictive value of changes induced by biological treatment in PsA.


Water column profiles of S2O32‐ and SO32‐ were obtained in January and May 2004 in the eastern portion of the Cariaco Basin (10°30'N 64°40'W). Mean concentrations in the chemocline (250 to 450 m) decreased from 2.3 ± 1.1 µmol L‐1 S2O32‐ in January to 1.4 ± 0.3 µmol L‐1 S2O32‐ in May and from 4.8 ± 2.9 µmol L‐1 SO32‐ in January to 2.7 ± 0.7 µmol L‐1 SO32‐ in May. Integrated over this same depth interval, S2O32‐ was 459 mmol m‐2 in January and 287 mmol m‐2 in May and SO32‐ was 799 mmol m‐2 in January and 574 mmol m‐2 in May. During this time, the integrated chemoautotrophic production in the chemocline decreased from 26 to 13 mmol C m‐2 d‐1. The concurrent decreases in S2O32‐ and SO32‐ inventories and chemoautotrophic production are consistent with a decrease in the frequency or intensity of intrusion events. S2O32‐ and SO32‐ were present in the oxic portion of the water column, suggesting lateral transport from shallower areas containing H2S. Calculations suggest that sufficient O2 and H2S can be supplied to the interface by advection and diffusion to form S2O32‐ in sufficient quantities to support the observed levels of chemoautotrophic production. However, apparently ≪2% of the H2S needed to form the observed amount of S2O32‐ can be produced from the degradation of organic carbon sinking through the interface at this site. This suggests either that the H2S or carbon flux must be supplied laterally, perhaps from shallower areas (not yet sampled), or that chemoautotrophic production near the interface is overestimated.


The purpose of this essay is to use a legal dogmatic method, and with a critical perspective, analyse how the fact that a crime is one of omission, thus caused by a failure to act, affects the Court's judgement on a suitable sentence. Is the fact that a crime is an omission automatically a mitigating factor that leads to a lesser sentence? This essay treats the general legal principles and the regulation of omission crimes in Swedish law, along with the legislation ordering the sanction. Towards the end of the essay, the question studied is treated with respect to a real life example, the so-called "Yara case".
The question of this sanction in Swedish law becomes highly relevant in the "Yara case", in which both a man and a woman were convicted of the murder of their eight-year-old niece Yara. Yara had come, just a year before her death, to Sweden from Palestine to escape the war. While her parents were still in Palestine, she lived with her aunt and uncle who had full custody of her. The 30th of April 2014, Yara's aunt committed an assault that caused the girl to die. The uncle was present in the apartment but failed to act to stop the assault. The Swedish court found them both guilty of murder. The woman's sentence was life imprisonment while the man's sanction was only 14 years in prison. His crime being one of omission was seen by the judges as a mitigating factor.
For a crime of omission to become punishable in Swedish law, the perpetrator must have an obligation to act strong enough to make the omission as punishable as a deed caused by an action. This is contradictory to the general opinion among Swedish lawyers, who believe that an omission is a mitigating factor. After an analysis of the crimes of omission and the legislation of a sentence, along with my practical example, I will arrive at the conclusion that even though a crime committed by omission usually is mitigating, there are many reasons not to assume that this is always the case. Especially punishable are crimes of violence against children. In those cases the obligation to protect is so strong that consciously failing this duty can never be a mitigating factor and thus lead to a reduction of the sentence.


The cultural role of Allen Ginsberg does not fit a typical Weberian model of charisma. The avant-garde poet was an outstanding personality and possessed an unusual ability to affect people. He played a vital role in expanding the boundaries of personal freedom in America of the 1950s–1990s, blazing new paths for spiritual, communal and artistic expression. Serving as a father figure for the counterculture—a symbol of an alternative set of cultural norms, lifestyles and literary forms—Ginsberg was a charismatic counter-leader, with no clearly defined followers or movement. As a leader in a more liberated era, he offered energy, ideas, inspiration, and color, but no structure or authority. Instead he was a prophet of freedom, calling on people to express themselves openly, to expand and experiment. This role demanded charisma but of a different kind—one that was more spiritual and less organizational or hierarchical. This article follows Gary Dickson's essay "Charisma, Medieval and Modern," in offering a suggestive analysis of and supplement to Weber's understanding of charisma. The article grapples with the concept of charisma in relation to a generation that resented rigid structures and authorities.


A gapped ground state of a quantum spin system has a natural length scale set by the gap. This length scale governs the decay of correlations. A common intuition is that this length scale also controls the spatial relaxation towards the ground state away from impurities or boundaries. The aim of this article is to take a step towards a proof of this intuition. We assume that the ground state is frustration-free and invertible, i.e. it has no long-range entanglement. Moreover, we assume the property that we are aiming to prove for one specific kind of boundary condition; namely open boundary conditions. This assumption is also known as the "local topological quantum order" (LTQO) condition. With these assumptions we can prove stretched exponential decay away from boundaries or impurities, for any of the ground states of the perturbed system. In contrast to most earlier results, we do not assume that the perturbations at the boundary or the impurity are small. In particular, the perturbed system itself can have long-range entanglement.


This paper based on the analysis of domestic economic and political factors and foreign ones which resulted in the act of world trade protection,and summed up new features in the current round of trade protection,including developed countries participating in a wide range,making more use of regional economic integration organizations to engage in collective protection,as well as broader protection object,more diverse and subtle means of protection and others. In this paper the author puts forward that in order to cooperate and step out of the vicious cycle of trade protection,countries should regard worldwide conferences as a platform,regional economic integration organizations as the basis,WTO rules as the protection,completion of Doha Round negotiations as a means.


Social media platforms such as Twitter have been used by political leaders, heads of states, political parties, and their supporters to strategically influence public opinions. Leaders can post about a location, a state, a country, or even a region in their social media accounts, and the posts can immediately be viewed and reacted to by millions of their followers. The effect of social media posts by political leaders could be automatically measured by extracting, analyzing, and producing real-time geospatial intelligence for social scientists and researchers. This paper proposed a novel approach in automatically processing real-time social media messages of political leaders with artificial intelligence (AI)-based language detection, translation, sentiment analysis, and named entity recognition (NER). This method automatically generates geospatial and location intelligence on both ESRI ArcGIS Maps and Microsoft Bing Maps. The proposed system was deployed from 1 January 2020 to 6 February 2022 to analyze 1.5 million tweets. During this 25-month period, 95K locations were successfully identified and mapped using data of 271,885 Twitter handles. With an overall 90% precision, recall, and F1score, along with 97% accuracy, the proposed system reports the most accurate system to produce geospatial intelligence directly from live Twitter feeds of political leaders with AI.


Large clods (centimetres in size) can be formed by tillage in clayey paddy fields where upland crops are planted. These clods cause early water depletion near the soil surface, which decreases crop germination and emergence rates. Because of the difficulty in reducing clod size, desiccation damage to seeds can be avoided by adjusting the seeding depth based on the clod size‐dependent soil moisture profile. This study aimed to clarify the effect of clod size on (1) the evaporation rate (E) and soil moisture profile and (2) the mobility of soil water during the drying process. Evaporation experiments were conducted in an air‐conditioned greenhouse with natural light using cylindrical columns filled with artificially made clods 3 (L columns) and 1 cm (S columns) in diameter. We measured E, potential evaporation rate (PE), and total soil moisture content (wtot) throughout the experiment and the soil moisture profiles at the end of the experiment. The water diffusivity (Dw) and apparent vapour diffusion coefficient (dvap) were calculated as the mobility of soil water and water vapour, respectively. We found that wtot was lower in the L column than in the S column, although not at the onset of the experiment. At the end of the experiment, the soil moisture content was lower in the L column than in the S column throughout the soil layer. In contrast, E/PE was higher in the L column than in the S column throughout the experiment and even at the same wtot. Regarding mobility, Dw was slightly greater in the L column than in the S column in the soil moisture content range, where vapour movement could be greater than liquid water movement. In addition, the ratio of dvap to the diffusion coefficient of water vapour in soil was higher than unity in both columns and was 2.4–3.2 times higher in the L column than in the S column. In summary, larger clods caused a higher evaporation rate and lower soil moisture content, owing to the increased enhancement of water vapour movement probably induced by wind.


With the rapid progress and improvement of society and economy, the importance of urban modernization has gradually become prominent, and the garden landscape design of urban residential areas is very vital for urban construction. However, in the garden landscape design of urban residential areas, various factors need to be considered, which leads to a significant increase in its complexity. Aiming at the problems of large judgment error and low efficiency in traditional judgment methods, a method for judging the rationality of landscape design based on remote image acknowledge is proposed. However, there are many problems that need to be paid attention to in the garden landscape design of the urban residential area, and the garden landscape design work of the urban residential area is also extremely complicated. Therefore, it is very vital to improve the landscape design of urban residential areas. Based on remote image acknowledge, this paper uses weights to express the rationality of landscape design for remote image acknowledge, which can implement robust acknowledge algorithms and analyze the rationality weights of landscape design for remote image acknowledge. Identify the rationality of landscape design to judge.


Land of Sunshine: An Environmental History of Metropolitan Los Angeles is a fascinating anthology on the relationship between the City of Angels and its often-turbulent environment. The nineteen essayists, which include scholars from a number of disciplines, set out to explore, in the words of editors William Deverell and Greg Hise, "a large set of regional environmental factors, environmental perspectives, and environmental challenges" (p. 1). Deverell and Hise have high expectations for the collection, hoping that Land of Sunshine will contribute to contemporary discussions on the sustainability of the greater Los Angeles region in particular, and urban-industrial society in general. With this goal, the editors, in a solid introduction, press the often-repeated but seldom recognized idea that history, indeed, "matters." Contributing scholars have the difficult task of investigating the relationship between successive social, economic, and cultural regimes and the southern California ecosystem. In this regard, the "metropolitan nature" of Los Angeles comprises the primary theme of the book. Borrowing from the concepts of the effects of city building on neighboring regions advanced by William Cronon, Donald Worster, and a host of other scholars, Land of Sunshine's authors examine "how people transform nature in particular sites and ... how what is created in particular locales is generative for local and broader culture" (p. 4). Planning is a unifying feature of Los Angeles's environmental history, and as a result, the city begins "the twenty-first century struggling with the consequences of success," in its urban arrangements, "both hoped for an unintended" (p. 10). As Deverell and Hise point out, "functional segregation ... which we now decry, was seen by sanitarians, social workers, progressives, and advocates for urban redevelopment as a cure-all for urban ills" (p. 6). Other reformers saw the automobile, now the bane of many Southland residents, as a critical tool for blurring the divisions between urban and rural. Well-meaning proponents of exclusionary zoning and early forms of NIMBY-ism (The


Nineteenth-century Russia reverberated with ideas of women's liberation as a condition of genuine equality in society. These ideas came to form the basis of an entire tradition linking the "woman's" question and the "social" question together and defining the democratic character of the women's movement in Russia.


2-[1-(Trimethylsilyl)vinyl] -2-adamantyl cation (2) was prepared by the ionization of 2-[1-(trimethylsilyl)vinyl]-2-adamantanol in FSO 3 H/SO 2 CF at -130 o C and was characterized by 13 C NMR spectroscopy. For comparison, the 2-vinyl-2-adamantyl cation (4) was similarly prepared and characterized. The cationic center of 2 is deshielded by 11.5 ppm over that of 4, indicating no β-silyl stabilization effect (either inductive or hyperconjugative)


in the monitoring station reflected my image throughout all three centrifuge runs. I was unaware that the personnel in data acquisition, located in a nearby building, were recording all communications on electromagnetic tape. In the centrifuge, I diligently concentrated on performing a psychomotor test. My task was to match programmed red lights (vertical and horizontal) with movable green lights. Individual test patterns were reflected. When I successfully matched one pattern by manipulating a right-hand device, another test pattern would follow immediately. My left hand continuously grasped a braking device, which consisted of a fixed-stick grip with an abort button, that would have permitted me to stop the centrifuge had I deemed it necessary. When I reached +5 Gx, the central observer asked me to repeat after him the increase in accelerative forces


Scientists continue to study SARS‐CoV‐2, the virus currently responsible for a worldwide pandemic, to determine the best methods to inactivate the virus on surfaces and reduce the risk of contact transmission. Its classification as a Biosafety Level (BSL) ‐3 pathogen complicates research since few facilities have the capacity for this level of containment. Human betacoronavirus OC43 (OC43) is a good surrogate for SARS‐CoV‐2 based on its genetic similarity and OC43's BSL‐2 classification. Two industry specific surfaces were inoculated with OC43 and sampled at timepoints that reflect typical industry timelines for sanitation. The objective was to determine the stability of OC43 on typical meat facility surfaces.


An overview of University of Arizona cooperative research efforts towards enhanced solar powerprediction over PV system operational lifetime is provided. Integration of established research programs in power forecasting (including irradiance and irradiance-to-power modeling) and indevice and system-level performance degradation studies offer new opportunities to address solar power prediction needs over short- and long-term time horizons.


As a milestone in the history of C.P.C.,the Eighth National Congress of C.P.C.is the first national congress convened after the Party came into power.The Congress served to be the starting point for the formation of the Party's ideology and the objectives of exercising power,and for the change of the Party's functions.Therefore,the Congress is regarded as the starting point for transition from a revolutionary party to a ruling one.


The aim of this paper is to provide a broad overview of the literature on diversity and music education and its relationship with the primary and secondary education Brazilian legislation. Thus I performed a research that included official educational documents and academic production of national and international music educators. Among the findings, I point out the different concepts that take part of the theoretical construct of the concept of diversity in music education, such as multicultural music education, intercultural competence, and others. In addition, I describe other categories that were included more recently, such as gender, race, sexual orientation, and which resemble those made explicit in the documents relating to primary and secondary education. The concept of multicultural music education, which emphasized the repertoire, has been expanded, thus including other categories, making it more inclusive. This change can not be just rhetoric or made with the purpose of complying with the legislation, but, rather, it should reflect the political st ance of music educators.


Water retention in soils as a function of suction is important in many disciplines, including engineering when assessing soil strength in infrastructure, and land management, agriculture and eco-hydrology. Water retention is described mathematically using a soil-water characteristic curve (SWCC), and many equations have been proposed which link degree of saturation, suction and voids ratio. They are empirical and phenomenological in origin, rarely incorporate both the particle size distribution and a description of pore geometry, and may not be valid for a soil in which pore surface area must remain constant and equal to particle surface area. Here, focusing on fractal soils, by setting particle and pore surface areas equal and constant, analytical derivations are presented linking all parameters defining SWCCs to particle and pore geometry information, size distributions, shapes, volumes and surface areas. Descriptions of how pore shapes and volumes depend on voids ratio are incorporated. The derivations...


Rheumatoid arthritis patients are inherently at higher risk of melanoma, but a new study shows that biologics do not increase that risk.


This thesis examines the ally and adversary reconstruction problems. Both are generalizations of the famous reconstruction conjecture. The results given here provide new insight to the reconstruction conjecture, and to the development and analysis of algorithms for graph reconstruction.
In this thesis, all graphs considered are simple, finite, and undirected. A vertex-deleted subgraph or card, G$-$v, of a graph G is obtained from G by deleting the vertex v and all edges incident to v. The deck of a graph G, denoted D(G), is its collection of cards. Two graphs G and H are said to have k cards in common if $\mid$D(G) $\cap$ D(H)$\mid$ = k. A graph G is reconstructible from a subset C of its deck if every graph H whose deck contains C is isomorphic to G.
The problems studied can best be understood in terms of an ally and an adversary. We are given cards one at a time from a graph G. G is reconstructible from the cards given, but is not reconstructible if the last card is omitted. In the case of ally reconstruction, an ally chooses the cards so that as few cards as possible are needed to reconstruct G. For adversary reconstruction, an adversary chooses the cards so that as many cards as possible are needed. The ally-reconstruction number of a graph is the number of cards the ally selects; the adversary-reconstruction number is the number the adversary chooses. Results proved in this thesis are: (1) Almost all graphs have ally and adversary-reconstruction numbers equal to three. (2) Regular graphs can have ally and adversary-reconstruction numbers at most n/2 + 2. (3) A disconnected graph is recognizable given any n/2 + 2 cards. (4) The adversary-reconstruction problem for disconnected graphs is essentially as difficult as that for general graphs. (5) The only disconnected graphs which can have ally-reconstruction number greater than three are those whose components are all isomorphic. In this case, the ally-reconstruction number is at most c + 2 where c is the order of a component. (6) Trees on five or more vertices have ally-reconstruction number three. (7) We give a family of pairs with $n\over 2$ + $\biggl({n + 1.125\over 8}\biggr)\sp{1/2}$ +.375 common cards. No families with more common cards are known. (8) If G and H are graphs with different degree sequences on n $>$ 6 vertices, they have at most n $-$ 2 common cards.


This paper aims to analyze the epidemiological profile of the human anti-rabies care after exposition as well as to describe and to characterize its proper indication. It is a descriptive, documentary study with a quantitative approach, approved by the ethics and research committee (CEP) at FACID. It used the data obtained from the files of SINAN (Brazilian Information System for Disease Notification) filled out in health environment by the professionals who are responsible for the anti-rabies treatment in a renowned hospital in Teresina-PI in 2012. The data collected were used in specialized software and the results shown in tables. Such results showed that out of the 482 cases investigated in the sample, 53% of the individuals were male; 57% were at the age group 20-59. The bites represented 98% of the assaults, dogs were prevalent in 80% of those assaults and 47% of the injuries were in the upper limbs. Out of the aggressor species, 86% were healthy and observable animals. The observation of the aggressor animal is very important to decrease dispensable treatments preventing unnecessary expenditure. Descriptors: Rabies. Epidemiological vigilance. Health profile. RESUMEN


One of the common infections among children is urinary tract infection. To reduce the morbidity associated with UTI, it is very important to diagnose promptly and initiate correct management. Signs and symptoms vary among different age groups, as well as some clinical features are nonspecific. Hense, accurate diagnosis is challenging and which is masked further by wide use of antibiotic prior to the collection of urine for culture and full report. Use of correct antibiotic for appropriate duration is crucial in management. Ideal image protocol in subsequent follow-up is still not very clear and debatable among majority.


The effects of added acids and salts on the hydrolyses of 3-phenylsydnone and 3-m-nitrophenylsydnone have been studied in both water and aqueous dioxan as solvents. The mechanism of hydrolysis is shown to involve specific hydrogen ion catalysis and nucleophilic catalysis by the anions of the acids involved. Values of the Hammett acidity function H0 are reported for hydrochloric and hydrobromic acids in 40% dioxan–water.


For non-oriented cold-rolled silicon steel lubricated with oil-in-water (O/W) emulsion, the typical white-stripe defects can always be found on the rolled strip surface. The white-stripe defects are parallel to the rolling direction. In this paper, an experimental investigation and mechanical analysis were carried out to study the white-stripe defect formation during cold strip rolling using atomic force microscopy (AFM) and scanning electron microscopy (SEM). The emulsion lubricating properties and surface topography of wear scars are discussed. It is considered that the poor lubricating properties of the emulsion are a key factor for surface defect formation on the rolled strip surface. The surface roughness R a of the white-stripe area is 31.2% larger than that of the normal area. The results show that when the tribological properties of commercial emulsion are poor; it will lead to generate surface defects on the rolled non-oriented silicon steel surface. Furthermore, emulsions were embedded into the surface defects of the rolled strip. When the emulsion residue agglomerates together, white-stripe defects appear on the rolled strip surface.


Following the HERO Model (Healthy & Resilient Organizations Model; Salanova, Llorens, Cifre, and Martinez, 2012), healthy organizational practices are a key resource in order to increase wellbeing at work (i.e., work engagement). In this exploratory study, we analyze the association between that healthy organizational practices and work engagement. The sample was composed of 218 employees from an industrial organization. Structural Equation Modeling results show that healthy organizational practices are positive and significantly related to work engagement (�� = .40, p < .001). The healthy organizational practices that showed the highest relation to work engagement were, from highest to lowest, psychosocial health, skills development and career development.


The k-means problem is arguably the most well-known clustering problem in machine learning, and lots of approximation algorithms have been proposed for it. However, many of these algorithms may become infeasible when data is huge. Sub-linear time algorithms with constant approximation ratios are desirable in this scenario. In this paper, we first improve the analysis of the algorithm proposed by [1] by sharpening the approximation ratio from $4(\alpha+\beta)$ to $\alpha+\beta$. Moreover, on mild assumptions of the data, a constant approximation ratio can be achieved in poly-logarithmic time by the algorithm. Furthermore, we propose a novel sub-linear time clustering algorithm called $Double -K-M C^{2}$ sampling as well. Experiments on the data clustering task and the image segmentation task have validated the effectiveness of our algorithms.


A radiochemical method was employed to obtain poly(1-trimethylsilyl-1-propyne)(PTMSP)-divinylbenzene (DVB) grafted films. DVB monomer vapors were absorbed by the PTMSP, and the grafting reaction was thereafter accomplished by {sup 60}Co {gamma}-irradiation in a nitrogen atmosphere. The films so obtained were tested for nitrogen-oxygen separation. The performances of the membranes were studied as functions of time and percent of grafting. The DVB-grafted membranes show an increased selectivity factor and stability with time. The experimental data and some SEM observations confirm the presence of large voids in the PTMSP matrix. These voids are responsible for permeability changes during operation and disappear after the grafting procedure. 8 refs., 5 figs.


Objective: To explore the value of heart rate in predicton the volume of acute upper gastrointestinal hemorrhage by comparing the gastrointestinal hemorrhage with the acute non-gastrointestinal hemorrhage in rabbits. Methods: Rabbit models of acute upper gastrointestinal hemorrhage and acute non-gastrointestinal hemorrhage were established. The heart rate change was observed in two different models of with different amount of hemorrhage. According to the heart rate change between two groups differences, the value of heart rate in prediction the volume of acute upper gastrointestinal hemorrhage were explored . Results: There were some associations between the amount of acute upper gastrointestinal hemorrhage and the heart rate. Heart rate in acute upper gastrointestinal hemorrhage did not increases proportionally to the amount of hemorrhage. It was different from the acute non-hemorrhagic gastrointestinal hemorrhage. there was a significant difference in heart rate changes between two groups. Conclusion: There are differences between the model of acute upper gastrointestinal hemorrhage and the model of acute non-gastrointestinal hemorrhage. But it could still be used to predict the volume of acute upper gastrointestinal hemorrhage


People who work in a research, academic or business envi ronment often have personal information collections which are large enough to need retrieval aids. A major difference between personal information retrieval and normal docu ment retrieval is that the items to be retrieved are often associated with events in the searcher's life and can be retrieved by their relationship to other events as well as by content. This paper describes some of the background to event-based retrieval and then describes a prototype graph ical event-based retrieval system.


The blood brain barrier (BBB) is a specialized membrane that covers the blood vessel in the central nervous system. This structure regulates the passage of certain substances for keeping the homeostasis into the brain. But this selective permeability is a drawback in treatments for neurodegenerative diseases, because the BBB prevents the passage of drugs to the affected brain cells. The use of focused ultrasound (FUS) has proven to be a promising tool for the BBB disruption in specific zones, which improves the release of drugs. One of the problems of FUS is the high attenuation of cranium. This paper presents a study of the acoustic field pattern and the disruption of the BBB in rat's brain for different diameters of craniotomies. These experiments were carried out in rats wistar. A 2 MHz FUS transducer of 10 mm radius and a focal length of 20 mm was used. It was found that a craniotomy of 1 cm allows the focus to be on the substantia nigra, our area of interest, without excessive field distortion and transmission losses.


The condition of the industry sector that is occurring among Indonesian people is currently experiencing significant achievements. This achievement can be seen from the number of companies engaged in manufacturing ranging from small to large scale. The most important element in a manufacturing company is the production department. If the production process goes well, it will have a good impact on the company. But in reality there are still many problems found in the production section in the form of waste. Waste that occurs is a waste of time, starting from the ineffectiveness of workers in processing a product that causes late production deadlines, then the waste of energy is the lack of labor productivity that causes less than the maximum number of products produced. Based on the results of research using the Borda count method (BCM), it is obtained waste that causes reduced work efficiency. Obtained the most dominant cause in influencing the reduction in work efficiency is waste unnecessary movement. From the analysis using a fishbone diagram, it is found that the cause of unnecessary movement waste is careless workers putting equipment after using it.
Keywords: Manufacturing, Production department, Borda Count Method