WAVE/DSRC technology provides various standards for the wireless access in vehicular environment i.e. IEEE 802.11 and IEEE 1609 family. The wireless network is the integration of all type of networks. The vehicular ad hoc network is the sub class of mobile ad hoc network. In vehicular ad hoc network vehicles are serving as nodes and it offers certain intelligent activities. It is an intelligent network of vehicles, called Intelligent transport System. It provides safety, driver assistant services and comfort to the road users. It also includes all type of communication in vehicles between Vehicle to Vehicle and Vehicle to Infrastructure.


Pavement management concepts are discussed, and a method is presented illustrating the required data and its use to accumulate EAL's annually for comparison with the design EAL. This method can be used to determine overlay priorities, overlay design thicknesses, and financing schedules. A discussion of automatic feedback of field data is presented. Pavement condition reports should be analyzed separately to prevent improper adjustments in the design system due to causes of failure than normal fatigue. An overlay, whether for extending service life or improving skid resistance, provides an additional structural thickness and will modify the design life. Preparation of the R-R-R cost estimates in the fall of 1976 offered the opportunity, and necessity, to implement a pavement management scheme. The methodology used to prepare the cost estimates are discussed in relation to overlay design and scheduling of resurfacing on the Interstate System in Kentucky. There are compounding and confounding factors which may distort pavement performance and confuse a pavement management scheme based only on the structural adequacy of the pavement. Such factors and influences as D-cracking, expansive aggregates, ditching, skid resistance, roughness, and rutting are discussed. /Author/


Some new retarded weakly singular integral inequalities of Gronwall-Bellman type are established, which generalized some known weakly singular inequalities and can be used in the analysis of various problems in the theory of certain classes of singular differential equations, singular integral equations and singular evolution equations. Using the modification of Medveď's method, the explicit estimations of unknown function in the inequalities are obtained. Finally, we give a examples to illustrate applications of our results.


The Life of Stephen King "Salem's Lot" "The Shining" "The Stand" "The Dark Tower III - The Waste Lands" "Needful Things" "Insomnia" "Dolores Claiborne" and "Rose Madder".


Crisis situations, which are a threat to brands to sustain their existences and activities, have acquired a different dimension, as a new media technology has arisen in the 21st century. Even though brands try to prevent social media posts against them, they can fail due to the rapid access and interaction advantages that the internet provides individuals. In this study, the Watsons crisis, which took place in 2016, will be considered not from the viewpoint of brands but, the individuals' organizations via social media in the context of social responsibility against the brands are discussed. Twenty of the 200 messages written under the hashtag of #WatsonsBoykot on Twitter, a microblog, was taken as a sample and analyzed through content analysis, Twitter.


Chronic Kidney Disease (CKD) is an increasingly prevalent condition affecting 13% of the US population. The disease is often a silent condition, making its diagnosis challenging. Identifying CKD stages from standard office visit records can help in early detection of the disease and lead to timely intervention. The dataset we use is highly imbalanced. We propose a hierarchical meta-classification method, aiming to stratify CKD by severity levels, employing simple quantitative non-text features gathered from office visit records, while addressing data imbalance. Our method effectively stratifies CKD severity levels obtaining high average sensitivity, precision and F-measure (∼93%). We also conduct experiments in which the dimensionality of the data is significantly reduced to include only the most salient features. Our results show that the good performance of our system is retained even when using the reduced feature sets, as well as under much reduced training sets, indicating that our method is stable and generalizable.


The article is devoted to the system of spatial oppositions and images in Nabokov's play and their functions in modeling emigre's reality.


A frequency domain analytical tool that verifies stability robustness for structured uncertainty consisting of real parameter variations is described. The method provides a nonconservative measure of the system's stability margin. It utilizes a numerical technique based on homotopies to ensure that a global minimum has been found.


Unconventional Food Plants (PANC) is a strategy for valuing biodiversity, food sources and nutritional resources. For there to be a correct consumption, studies on PANC are necessary. Bio accessibility has been used for analyzes on the mineral content present in certain foods, and if a high content of these components in THE PANC is proven, they may emerge as an alternative to supply the mineral deficiencies present in part of the population. The aim of this study was to evaluate the contents and bioaccessibility of macro and micronutrients of four unconventional food plants used in the Amazonian gastronomy. The PANC sums used were: holy grass, Amazonian spinach, macuco beans and ora-pro-nóbis. The nutritional analyzes performed were: Humidity; Ashes; Lipids; Proteins; Carbohydrates; Total fibers; Minerals; pH; Titratable acidity; Color reflected; Ascorbic acid and bioaccessibility. The holy grass showed significant nutritional values in the contents of lipids, carbohydrates, fibers, sodium and vitamin C. Spinach Amazonian in natura showed significant values for protein and fiber. When bleached it showed higher values for moisture and protein. Macuco beans stood out in ash, fibers and vitamin C. Ora-pro-nobis in natura showed higher values for proteins, moisture, manganese, calcium, potassium, magnesium and vitamin C. When bleached, it showed significant results for carbohydrate, iron and zinc. In the titratable acidity only two samples suffered significant variations in heat treatment, holy grass with fresh sample, bleached sample and Amazonian spinach, with fresh sample and bleached sample. At pH, bleached Amazonian spinach was determined as the sample with lower acid character, none of the samples presented an acidic character, the one with the lowest value being bleached macuco beans. In the results, the PANC showed high nutritional values mainly in micronutrients and are a good alternative for insertion in the diet of the local population because they are cheap and easily accessible. The most significant value of oxalic acid found in the studied samples was determined in the samples of in natura and blanched cariru, both with 1.08% and in the blanched macuco bean sample with 1.08%. The results differ from the values found by Germano et al., (2002) who determined oxalic acid in bean samples with the most diverse mixtures. In the analysis of oxalic acid there were no statistically significant differences between the mixtures, but the highest proportions were in the mixtures with spinach.


Quadratic rotation combinatorial design was utilized to optimize suspension culture conditions for resveratrol production by peanut root callus tissue.Under the following optimized conditions:shaker rational speed 130 r/min;inoculum size 38.00 g/L;pH 5.80;and sucrose concentration 40.00 g/L,the maximum proliferation fold of suspension cells was 4.71±0.04,and the resveratrol production reached 907.3 μg/g after 15-day incubation.


the death of his son changed his personaUty and created quite a different presidency than would have almost surely been the case had his son not died. Lyndon Johnson's exaggerated and seU-destructive ambition that was fueled by an early fear of failing his mother is implicated in some of his best, and some of his worst, policies. These are just some of the fascinating and perceptive analyses offered in this book. Any careful reviewer would find something with which to find fault—the aUegations surrounding amphetamine abuse by Kennedy should have been given more attention, and Reagan's distant management style might have been considered as more of a style than as a defect bordering on pathology. Gilbert was selected in 1995 to be a member of what was to become President Clinton's Working Group on Disability of United States Presidents. Among other matters (such as the organization of the White House Medical Unit) this body considered changes in the Twenty-fifth (disability) Amendment to the constitution. The report was made to the President after a White House conference in the Fall


3380 Mitchell Lane, Boulder, CO 80301, USA, 303-415-9701 x201, firstname.lastname@example.com lorado Research Associates, 3380 Mitchell Lane Boulder, CO 80301, USA, 303-415-9701 x201, firstname.lastname@example.com Figure 1. The snowfall distribution (in) in NE Colorado during the period March 17-20, 2003. Courtesy Denver National Weather Service. The thick dashed line denotes the Continental Divide. 30 km EXCEPTIONAL MESOSCALE FEATURES OF THE GREAT WESTERN STORM OF MARCH 16-20, 2003


A general mathematical framework is presented to describe local equivalence classes of multipartite quantum states under the action of local unitary and local filtering operations. This yields multipartite generalizations of the singular value decomposition. The analysis naturally leads to the introduction of entanglement measures quantifying the multipartite entanglement (as generalizations of the concurrence for two qubits and the 3-tangle for three qubits), and the optimal local filtering operations maximizing these entanglement monotones are obtained. Moreover, a natural extension of the definition of Greenberger-Horne-Zeilinger states to, e.g., 2x2xN systems is obtained.


At the beginning of the 1990s, Romania inherited a disastrous child protection system from the communist regime. As a result of pro-birth policies and of the economic depression in the 1980s, the traditional models of child care in the family, especially for children in need (in particular those with disabilities) were undermined. The government of Romania has made significant progress in the past 25 years in terms of reducing the number of children in public care. Despite the large number of children placed in public care, the government of Romania has acknowledged the fact that the residential type of care has negative effects, especially on the development of young children, and has managed to improve child protection services substantially by developing family-type care alternatives. However, following the global crisis, which affected the situation of children in the entire Central and Eastern Europe/Commonwealth of Independent States region, the process of reducing the number of institutionalized children slowed down significantly, both in Romania and in other countries in the region. This book presents the results of this research on more than 52,000 children placed in public care in Romania (in special protection) who receive family or residential-type protection services, as well as on the children at risk of separation from their families from the source communities. The whole analysis in this volume is child-centered, encompassing both children in the special protection system and children at risk of separation from their family. The results presented in this book have been and would be discussed with the central and local authorities in Romania in order to identify the priority steps required to advance the reform of and increase investments to the child protection system reform.


Background: Ectopic pregnancy poses a major health and reproductive challenge to childbearing women. It is a significant hemorrhagic disorder that continues to contribute substantially to maternal morbidity and mortality. This is an error of zygote implantation outside the endometrial cavity with consequent rupture and or death of the fetus because of the failure of implantation site to sustain further fetal growth and development. Unless timely interventions, the consequences of ruptured ectopic pregnancy can be life-threatening. Objectives: To measure the incidence of ectopic pregnancy in the Niger Delta University Teaching Hospital, determine its contribution to early pregnancy loss, case-fatality rate and investigate the possible associated risk factors and other relevant correlates. Methods: Data on each ectopic pregnancy that presented from 2015 to 2020 were collected and analyzed. Results: Ectopic pregnancy constituted 6.3% and 23.9% of gynaecological admissions and surgeries respectively and an incidence of 2.8% of live births and 2.3% of all pregnancies managed. Median age of patients was 29 (interquartile 25-34) years, the leading identifiable risk factors were previous induced abortion (72.7%), intra-abdominal surgery (23.6%) and multiple sex partners (21.5%). The commonest clinical presentation was abdominal pain (96.4%), dizziness/fainting spell (58.2%) and vaginal bleeding (41.8%). Mean estimated blood loss was 1593.6±702.8mls, 85.5% of the patients were anemic at presentation and 89.1% received blood transfusion. Tubal pregnancy was 94.5%, left tube 51.9%, ampullary 69.2% and isthmic 17.3%. All the patients had laparotomy, 92.7 % salpingectomy (49.1% left and 43.6% right). There was one death; a case fatality of 1.56%. Conclusion: Ectopic pregnancy still remains a major cause of maternal morbidity and mortality. Prior tubal damage, mostly from pelvic infection is the risk factor. Quality contraception, blood banking services and legalization of abortion will mitigate the impact of ectopic pregnancy


Overview of the Italian public pension system from 1969 to 2018. Economical implocations of an aging population and early retirement. A more in-depth view on quota 100 and the Italian labour market.


This paper will analyse Chillingworth from a different angle to show his another aspect: ready to help others, longing for love and marriage and devoting his whole life to the development of science. Probing the writing background and analysing the reasons that the author denies and discredits Chillingworth. The purpose is to help readers overcome the prejudice and have a overall apprehension to Chillingworth.


Research provides support for four theoretical explanations for relationship maintenance: equity, uncertainty, attachment, and reciprocity. This study focused on the relationships among these theoretical explanations, as well as whether the concepts might be combined to provide a single explanation for why an individual enacts maintenance behavior. Survey data were collected from 179 married individuals. Path-modeling techniques revealed that, counter to predictions, uncertainty did not mediate the relationship between equity and maintenance enactment. Further, there were significant correlations among variables associated with all four theories. A series of multiple regression equations indicated that the four theoretical concepts predicted between 16% and 68% of the variance in maintenance enactment. Among the four theoretical explanations, reciprocity was the strongest and most consistent predictor.


With there problems at hands,an improved random field,support vector machine conditional random field(SVM-CRF) was proposed.It uses SVM as its unary potential,combining the merits of SVM and CRF.Experiments using AVIRIS hyperspectral data as input were carried out,and SVM-CRF was analyzed extensively.Experimental results show that SVM-CRF is superior to SVM and classic CRF in terms of classification accuracies.


This paper is concerned with the construction of a small, but non-trivial, example of a polynomial identity algebra, which we call the \emph{Jackson algebra}, that will be used in sequels to this paper to study non-commutative arithmetic geometry. In this paper this algebra is studied from a ring-theoretic and geometric viewpoint. Among other things it turns out that this algebra is a"non-commutative family"of central simple algebras and thus parametrises Brauer classes over extensions of the base.


Machine learning (ML) is now widely used to empower products and services, but there is a lack of research on the tools that involve designers in the entire ML process. Thus, designers who are new to ML technology may struggle to fully understand the capabilities of ML, users, and scenarios when designing ML-empowered products. This paper describes a design tool, ML-Process Canvas, which assists designers in considering the specific factors of the user, ML system, and scenario throughout the whole ML process. The Canvas was applied to a design project, and was observed to contribute in the conceptual phase of UX design practice. In the future, we hope that the ML-Process Canvas will become more practical through continued use in design practice.


We investigated a trait of odor and the relationship between odor unit and odorous compounds using multiple regression analysis based on data compiled from Sihwa (SIC), Banwol (BIC), Banwol plating (BPIC) and Poseung industrial complex (PIC). These areas are odor control areas in Gyeonggi province. It was revealed that NH₃ and styrene concentrations in SIC and BPIC were relatively higher and H₂S concentration especially in BIC was more than five times higher than other areas. As a result of regression analysis using SAS, intensity of odor unit was highly related to concentrations of H₂S, TMA, styrene and n-valeraldehyde in SIC, H₂S, acetaldehyde, and butyraldehyde in BPIC and NH₃ in BIC.


Regular exercise is known to boost immunity, increase immune response to fight infection, as well as speeding up recovery times and healing processes. This study seeks to assess if exercising regularly pre- SARS-CoV-2 (COVID-19) and/or BMI status has an effect on recovery time. A total of 215 people infected with COVD-19 from the Kingdom of Saudi Arabia took part in this study (age 36 years, mass 72 kg, stature 166 cm). Only 10 patients were physically active and fulfil WHO physical activity requirement (Age 30 years, Mass 77 kg, Stature 176 cm). There was a significant difference in recovery time between active and inactive patients (P=0.00) with active patients recovery 2.7 times faster than inactive patients. Active patients showed a lower BMI level (p=0.043). Anthropometric measurement characteristics and the fitness level could be used in decision making scenarios for the estimation of the risk of complications in patients with COVID-19.


In the previous articles in this series, 1 we considered that the processes of agent-based transactions pose conceptual and practical legal problems: on the one hand there are issues of agent personality and consent, which may only have a legal solution (legislation, jurisprudence). On the other hand the practical problems such as procedural compliance, error captures and chains of causality may have technical solutions. Particular problems that have been highlighted include: I The attribution of responsibility for advanced agent contracting I Difficulties in complying with certain consumer protection regulations (notifications, confirmations, contracting procedures) I Privacy risks with regard to notifications and the provision of consent for personal data processing I Finding ways for creating legally valid agent-based advanced digital signatures. Certain issues have not been considered as they fell outside the scope of the particular agent processes that were analysed, such as IPR and database rights in relation to the interaction between agents and online content. 2 A central aim of research has been to maximise the benefits of agent computing and minimise the risks involved in agent-based commercial transactions. To do this, it seems to us that it is fundamental to embed the legal risk analysis and implications into the engineering design of agents. In our analysis, using concepts taken from process modelling and coordination theory, 3 we set out the business processes underlying the software agents under study, and identified associated legal processes and constraints. Through understanding the legal implications of the processes we may enable systems designers to create an abstract legal model or architecture of the transactions. This model can map the constraints and dependencies imposed by law and by contracts with third parties. At a higher level, this legal architecture could be mapped onto, or extend, the business process description of the organisation and its model, thus " legalising " the model. Privacy or IPR obligations may be embedded in the process model, and contractual rights and obligations may be defined so as to be interpreted and enforced at technology level. We believe that this legal architecture could be represented and implemented through a language that combines these constraints or dependencies with relevant ontologies and content languages (for describing in a computer meaningful and standard way the legal concepts) and computer based protocols. To develop such an approach and languages, it is essential to have a full understanding from a legal perspective of current technical …


This article refers to the theoretical and practical aspects of business, its development paths and strategy selection in Uzbek economy, the statistical analyses through methods of observation, collection of statistical data, classification, tabulation; and also diagrams and graphs frequently used in presenting data, dynamic changes, comparison and prognosis of indicators of the development of business, including the ways of improvement of private sector in the formation of economy as well as the perspectives of development of business in Uzbekistan.


The effective establishment of the victim's permission is closely related to the availability and degree of criminal responsibility.Therefore,strict discrimination and limitation of the condition and scope of the victim's permission can better guide judicial practice.As regards to the establishment of the victim's permission,the paper focuses its discussion on the promisee,the promised and the undertanding of the doer for the permission,etc.


The conversion to Pb-free solders has already been implemented in the consumer market. However, the transition to Pb-free solders in the high performance, mission critical networking/server industry has not yet been fully implemented. A significant factor in the slow transition to Pb-free solders is the absence of industry accepted Pb-free acceleration transforms that can translate lab test results into field reliability life data. Without such industry accepted acceleration transforms, it is difficult to translate lab test data into reliable predictions of field life performance. In this two-phase study, a comprehensive set of test data have been generated over a wide spectrum of package types, solder joint metallurgies, joint size, pitch, die sizes, PCB thicknesses and thermal cycling conditions. The effect of aging on acceleration transforms was also included. The data has been analyzed and compared with existing Pb-free and SnPb acceleration transform models. The data helps explain contradictions in t...


The paper studies some novel techniques for simplifying a near-maximum-likelihood detector that operates on a sequence of received samples, each of which carries two new data symbols. The two data symbols may originate from independent sources, and one of these may be an unwanted interfering symbol. In a received sample, the two new data symbols have been multiplied by arbitrary quantities that may vary independently, but smoothly, from one sample to the next. The new techniques are studied for a particular application of near-maximum-likelihood detection in a land-mobile-radio system, which introduces flat fading into the transmitted QPSK data signals. The receiver here employs an arrangement of combined detection and estimation that has recently been developed for use with the given signals. The arrangement enables two QPSK signals to be transmitted simultaneously over any one channel, in place of the one QPSK signal conventionally used, leading to a more efficient use of bandwidth. The paper shows how substantial simplifications may be introduced into the detection process without, however, significantly changing its resultant operation. The new techniques described here are of quite general application to many near-maximum-likelihood detectors, in applications over flat fading or frequency-selective fading channels, or over time invariant channels that introduce intersymbol interference.


policy choice between capital-intensive and labor-intensive techniques. China seems to be only incidental to the author's theoretical interests. His facts are not very detailed and all are second-hand. The uncritical use of the officially discredited statistics of the years 1958-59 is rather reckless. Compared to previous German works on the subject (Handtke, Grossmann) this one contributes some new analytical tools with which to study the Chinese economy, butas far as the empirical analysis is concerned it trails behind. While looking at the Chinese economy through the model of a dual economy, the author discovers that during the first five-year plan China was guided by the capital-intensive development policies, whereas during the second five-year plan it switched to the labor-intensive policies, which maximize employment while adapting technology to the existing factor endowment. He praises China for being the first socialist country to be so "rational," and he believes that this "new experiment" will also teach something to all other developing countries. Most students of China would of course disagree that the policy switch during the second five-year plan was a preconceived and rational decision. The author disregards the consequences of the sudden withdrawal of Soviet aid, the unprecedented natural calamities, and the continuation of American trade embargo, which all compelled China to turn to "rural industrialization." He also leaves unanswered the following crucial theoretical question: In what direction would techniques change if population growth continues to enlarge relative labor unemployment? They would have to become more primitive and the economy would stagnate more and more. Under such an assumption, what is needed are techniques which would secure full employment of the incremental labor force. It seems doubtful thai primitive techniques can do the job.


We propose a procedure to estimate the fatigue loads on wind turbines, based on a recent framework used for reconstructing data series of stochastic properties measured at wind turbines. Through a standard fatigue analysis, we show that it is possible to accurately estimate fatigue loads in any wind turbine within one wind park, using only the load measurements at one single turbine and the set of wind speed measurements. Our framework consists of deriving a stochastic differential equation that describes the evolution of the torque at one wind turbine driven by the wind speed. The stochastic equation is derived directly from the measurements and is afterwards used for predicting the fatigue loads for neighboring turbines. Such a framework could be used to mitigate the financial efforts usually necessary for placing measurement devices in all wind turbines within one wind farm. Finally, we also discuss the limitations and possible improvements of the proposed procedure.


Many satellite constellations have been planned from various countries. Optical communications are expected to realize wide bandwidths and the immunity to the interference under the environment of a huge number of satellites in the future. © 2022 The Author


Since this project is a result of a class assignment, it has been graded and accepted as fulfillment of the course requirements. Acceptance does not imply technical accuracy or reliability. Any use of the information in this report, including numerical data, is done at the risk of the user. These risks may include catastrophic failure of the device or infringement of patent or copyright laws. The students, faculty, and staff of Cal Poly State University, San Luis Obispo cannot be held liable for any misuse of the project. Abstract Most residential housing units do not have preventative measures in place to stop water flow into the house in the event of a water crisis. A residential water system circuit breaker was designed and fabricated to monitor water flow with logic able to recognize abnormal excess water flow. Upon recognizing irregularly large volumetric flow, the device will shut water supply off to the residence to prevent wasted water and water damage to the property. The design was based on ½ " diameter pipe fittings and would be solar powered in order to remove the dependence of the electrical grid. An electronic hall-effect flow sensor will communicate with a microcontroller to quantify inlet volumetric flow. The device's performance was tested using a recirculation pump with flow rates between 0-17 gallons per minute to simulate random residential water usage. During a sample monitoring period of each trial, an average maximum flow rate was calculated; water was then pumped at a constant 17 gallons per minute and the time to actuate the solenoid valve was the measured variable. These values were compared against theoretical values based on the logic programmed to the systems microcontroller. Results showed all experimental values to be within 4 second standard deviation with an average offset of 7 seconds. With the current software the device portrays positive performance results of recognizing an abnormal flow rate and actuating preventative flow stopping measures.


Abstract : The thermal expansions of lampblack base, coke base, hot worked coke base and pyrolytic graphites have been measured in the c sub o direction from 1000 to 2700 K by use of a high temperature X-ray camera. The results indicate that, (a) the coefficient of thermal expansion is not constant with temperature and (b) this coefficient increases with increasing crystallite perfection. The camera was modified to accept a low temperature attachment and the a sub o's and c sub o's of lampblack base, hot worked coke base, and pyrolytic graphite were evaluated at 6, 78 and 298 K. The three graphites showed similar expansion characteristics and, within the limits of error, seemed to show a negative a sub o expansion coefficient near 298 K.


It is a little known fact that while he was developing his theory of general relativity, Einstein's initial idea was a variable speed of light theory. Indeed space-time curvature can be mimicked by a speed of light $c(r)$ that depends on the distribution of masses. Einstein's 1911 theory was considerably improved by Robert Dicke in 1957, but only recently has the equivalence of the variable speed of light approach to the conventional formalism been demonstrated (Broekaert, 2008). Using Green's functions, we show that Einstein's 1911 idea can be expressed in an analytic form, similar to the Poisson equation. Using heuristic arguments, we derive a simple formula that directly relates curvature $w$ to the local speed of light, $w= -c^2 \Delta \frac{1}{c^2}$. In contrast to the conventional formulation, this allows for a Machian interpretation of general relativity and the gravitational constant $G$. Gravity, though described by local equations, has its origin in all other masses in the universe.


Follow the example of editing the numerical control program to manufacture cycloid internal rotor outline, briefly explain it's complexity and fussiness that takes points with program, simplicity and convenience that takes points with a method of angle deflexion, and introduce the function, work rules of angle deflexion device ED and application in production.


Traditionally, most historic buildings represent pre-21th century masonry structures. It is due to the extensive presence of such masonry structures that their behaviour under earthquakes will be analysed in this paper. First, this paper will outline the traditional methods and materials used in the construction of historic masonry structures. Second, a typical damage scenario will be described showing what happens when these historic structures are subjected to earthquakes. Reference will also be given to damage suffered by historic buildings under the latest catastrophic earthquakes in L'Aquilla, Haiti and Chile. The traditional, standard methods for repair are discussed. Then, the principles of the base isolation theory and the current hardware used for isolating structures is presented. Next, a time-history analysis of a historic masonry church is discussed, comparing the response of a fixed-base versus an isolated church. Finally, a review of the IZIIS' activities related to protection of historic buildings against earthquakes is given. It is concluded that base isolation is very applicable in retrofitting of historic buildings since it drastically reduces the seismic forces and enables protection of these structures by minimal interventions.


Solid phase micro-extraction coupled with gas chromatography-mass spectrometry(SPME/GC-MS) was applied to analyze the volatile components in 25 commercial vegetable oils and 41 gutter oils from the interceptor sewers of Hunan cuisine restaurants in Guangzhou. In total, 113 types of volatile components were detected in gutter oils, and 71 types were found in vegetable oils. Aldehydes and alkenes were the most abundant components of gutter oils, while vegetable oils contained mainly aldehydes and other volatile components. Acid components were most abundant in gutter oils, and vegetable oils contained only trace amounts of acids. Ethers and aromatics were detected in gutter oils but not in vegetable oils. Gutter oils generally contained limonene, which were not detected in vegetable oils. In addition, allicin was detected in gutter oils but not in vegetable oils. Therefore, large amounts of acids, ethers, aromatics, limonene, and allicin can be used as indicators for gutter oils. This provides a strong basis for the identification of gutter oils and adulterated vegetable oils.


Tracking moving targets from partial measurements is an important problem with applications in control theory and pattern recognition. This letter presents a statistical framework for modeling target motion as the output of a linear dynamical system driven by a random step function representing sequences of idealized target positions. Target trajectories are observed through a noisy nonlinear measurement function, whereas system parameters are modulated by a semi-Markov chain representing changes in target regime. An algorithm is presented for maximum-likelihood parameter estimation from a corpus of observations, and potential applications to articulatory speech recognition are discussed.<<ETX>>


The female of Parapsyche cardis Ross is described and the female of Parapsyche apicalis (Banks) is redescribed and illustrated. A key is provided to the genera of Hydropsychidae of the southeastern United States, based primarily on wing characters.


. The application of the Internet of Things (IoT) specific to Music technologies is referred to as Internet of Musical Things (IoMusT). This field is in its infancy but potential applications include wide network interactive music performances, smart and wearable instruments, and multi-person virtual music systems. There is no framework as of yet, but a number of technical hurdles have yet to be overcome. These obstacles reflect the fact that many devices will be wearable which means they must be lightweight, energy efficient, and possibly low cost, but must also be powerful. Music therapy is yet untouched by these new technologies of IoMusT. However, it offers great potential for devices that could be applied in assistive living scenarios that provide a non-invasive, individually attuned, form of treatment that is always available. For example, wearable devices that are driven by low cost computing could offer interactive music therapies that are delivered outside of the clinical setting. These could be used to enhance a patient's wellbeing in between instruction and practice sessions with a therapist. The usefulness of ubiquitous music technologies will be further extended with the development of machine learning algorithms that are designed specifically to have a low computational footprint. These could be used to analyze and predict user behavior and thus tailor the therapy exactly on each occasion. This paper will develop a review of what has been achieved in this domain so far. It will then look ahead to see which trajectories are most likely for the future, particular within the guiding framework of ubiquitous music and computing. It will close with a discussion on the key technological enablers and risks that could hamper their progress.


Pulsed photothermal radiometry of biological objects is described. The absorption coefficients of YAG:Er3+ and CO2 laser radiation and thermal diffusivities in various biological tissues were determined experimentally.


Objective:To observe the effect of Qishen Yiqi Dropping Pills on ventricular remodeling and function after myocardial infarction model in rats.Method:The myocardial infarction model of SD rat was established by logating the anterior descending coronary artery and then the rats were divided into myocardial infarction control group and medicine group(n = 16 in each froup).Meanwhile,a sham-operation group was build including 16 rats.The rats in medicine group were intragastrically given Qishen Yiqi Dropping Pill at the dose of 38 mg.kg-1.d-1.The rats in the control group and the sham-operation group were intragastrically given at the same dosage of normal saline.Eight weeks later,left ventricular end-diastolic pressure,left ventricular peak pressure,the maximum change rate of left ventricular pressure rise and fall,left ventricular mass and left ventricular mass index,serum and plasma angiotensinⅡ,tumor necrosis factor α,endothelin-1,brain natriuretic peptide,etc.were tested.Result:Eight weeks later,left ventricular end-diastolic pressure of the control group was higher than that of sham-operation group(P 0.05);left intraventricular systolic pressure,the maximum change rate of left ventricularpressure rise and fall were lower than those of the sham-operation group(P 0.05);serum ICAM-1 and plasma AngiotensinⅡ,tumor necrosis factor α,endothelin-1 and brain natriuretic peptide etc were higher than those of sham-operation group(P 0.05).After drugs intervention,left ventricular mass and left ventricular mass index,left ventricular end-diastolic pressure,serum angiotensinⅡ,tumor necrosis factor α,endothelin-1and brain natriuretic peptide of the rats in the medicine group were lower than those of the control group;left intraventricular systolic pressure,the maximum change rate of left ventricular pressure rise and fall were higher than those of the control group(P 0.05).Conclusion:Qishen Yiqi Dropping Pills can improve the ventricular remodeling and function for the myocardial infarction model in rats.


Presents the findings of a recent survey on developing future top managers. Coaching and mentoring are used to encourage managers to take ownership of their own career development but results showed only one‐third of companies surveyed carry this out. Reveals that there has been a hardening of attitudes towards high‐flyers.


Software process improvement programs are partly founded on software measurement. However, despite their importance, it has been pointed out in the literature that many students are leaving the academic world without the necessary skills to conduct this kind of process. This can be understood by people's attitudes to this process which is regarded as time-consuming and difficult to understand—factors that explain the lack of interest in it during a student's academic life. In light of this, the application of serious games or gamification can show useful alternative ways of meeting this need, because the strategies they involve are well accepted by students and have a motivational and engaging effect on them. The objective of this work is to discover different approaches to the teaching of software measurement and software process improvement through gamification projects and serious games. This involves carrying out a systematic review of the literature, which is aimed at characterizing the state-of-the-art on the use of methods related to gamification and serious games in the abovementioned subjects. We conducted a systematic review of the literature to identify primary studies that address the use, planning, or evaluation of gamification, serious games, their features, and game mechanics in software engineering. We located 137 primary studies, published between 2000 and 2019. Although the use of serious games and gamification in software engineering is not recent, there still remains a large area to be explored, especially in software process improvement and software measurement. The study expands and advances the research on how serious games and gamification proposals can be used for teaching software measurement in the context of software process improvement programs by conducting a systematic review of the literature.


The antimicrobial activity of a variety of aliphatic diols and their esters has been investigated. Inhibition of growth of Bacillus subtilis 60015 was found to depend on chain length and position of the hydroxyl groups. 1,2-diols were more effective than 1,3diols. Esterification also affected antimicrobial activity. Studies with membrane vesicles prepared from B. subtilis indicated that inhibition of amino acid transport is a primary antimicrobial effect of diols and their esters.


The non-isothermal crystallization behavior and kinetics of linear low-density polyethylene (LLDPE),LLDPE/SEBS,LLDPE/SEBS-g-MAH were studied with differential scanning calorimentry combined with the Avrami equation. The methods of Gupta,Jeziorny and Mo Zhi-shen for non-isothermal crystallization kinetics were used to analyze the crystallization characteristics,the results demonstrate that due to partial destruction of crystal region,the crystallization rate of LLDPE decreases with adding SEBS and its grafts. Addition of elastomer playes a inhibition for crystal growth of LLDPE. The fact that all samples had Avrami exponents in a range of 1.1~1.5 implies the nucleation mechanism and geometry of crystal growth of LLDPE was not changed.


The aim of this work is to study the hydrogenation processes in lithium-containing ceramics under high-temperature irradiation. Irradiation was carried out with protons with an energy of 1 MeV and fluences of 1015–1017 ion/cm2 at irradiation temperatures of 300–1000 K. The choice of irradiation conditions is due to the possibility of simulation of the radiation damage accumulation processes in the near-surface layer of Li2TiO3 ceramics, as well as establishing the dependences of changes in structural parameters during temperature heating of samples during irradiation. It has been established that at irradiation fluences of 1015–1016 ion/cm2, the formation of dislocation defects is observed, the density of which has a pronounced dependence on the irradiation temperature. At irradiation fluence above 5 × 1016 ion/cm2, an increase in the crystal structure deformation is observed, due to swelling processes as a result of implanted hydrogen accumulation in the near-surface layer structure. At the same time, an increase in the irradiation temperature leads to a decrease in the swelling value, which is due to the accelerated migration of implanted hydrogen in the near-surface layer and its release through the existing pores. Results of mechanical tests showed that the swelling of the crystal structure and its deformation leads to embrittlement and a partial decrease in the strength of the near-surface layer. The obtained research results will further allow us to evaluate the resistance of lithium ceramics to the processes of hydrogenation and destruction as a result of the formation of gas-filled cavities in the structure of the near-surface layer.


OBJECTIVE
To determine the efficacy of laparoscopic surgical techniques for repair of rectal lacerations in horses.

STUDY DESIGN
Experimental study.

ANIMAL OR SAMPLE POPULATION
Thirty-two segments of equine bowel placed in an equine pelvitrainer, 8 equine cadavers, and 3 normal horses.

METHODS
In experiment 1, 3 laparoscopic intestinal-repair techniques were evaluated in an equine pelvitrainer: suturing with needle holders, with an automatic suture device, and stapling with a hernia stapler. In experiment 2, descending colon lacerations were sutured laparoscopically using needle holders in a pelvitrainer and in equine cadavers. In experiment 3, iatrogenic rectal lacerations were sutured laparoscopically with needle holders in horses under general anesthesia. These horses were evaluated for 7 days' postoperatively by clinical examination and blood and peritoneal fluid analysis. The horses were euthanatized 7 days' postoperatively and necropsied. The repaired colonic segments were collected for determination of bursting pressures, degree of luminal narrowing, and microscopic examination of the suture line.

RESULTS
For the 3 techniques, there was no significant difference in repair time or degree of luminal narrowing, but bursting pressure was higher in segments repaired by use of needle holders or with the suture device. Colonic and rectal lacerations were sutured successfully with laparoscopic needle holders. No major complications were recorded. At necropsy, adequate healing was confirmed by a high bursting strength (>140 mm Hg) and by histologic examination.

CLINICAL RELEVANCE
A novel laparoscopic method can be used to repair iatrogenic rectal lacerations in horses. Whether this method may be used for clinical cases of rectal tears must be investigated.


OBJECTIVE. We investigated the effect of a combined neuromuscular electrical stimulation (ES) and dynamic hand orthosis (DHO) regimen with a group of people with chronic stroke to improve performance on specific daily tasks. METHOD. Four people with chronic stroke participated in an ES‐DHO regimen using the affected upper extremity 5×/wk for 6 wk. Outcome measures included grip strength, range of motion (ROM), and analysis of muscle activation‐deactivation during release of grasp through electromyography. Ability to perform specific daily living tasks was assessed using the Assessment of Motor and Process Skills (AMPS). RESULTS. Results suggested that improvements in strength, ROM, and grasp deactivation are possible with the combined ES‐DHO regimen. All participants' AMPS motor scores improved. CONCLUSIONS. An ES‐DHO regimen may improve motor skills needed for functional task performance in people with chronic stroke. Results should be interpreted cautiously because of the pilot nature of the study and the small sample size.


Cyanobacteria have long been associated with harmful effects on humans, animals and aquatic biota. Cyanotoxins are their most toxic metabolite. This review summarizes the current research, impacts and future needs in cyanobacterial studies undertaken in Portugal, the southernmost country of Europe, and with a recent multiplication of cyanotoxicity due to climate change events. Microcystins are still the most prevalent, studied and the only regulated cyanotoxins in Portuguese freshwater systems much like most European countries. With the development of some tools, particularly in molecular studies, the recent discovery of cylindrospermopsins, anatoxins and saxitoxins, both genes and toxins, in North and Center ecosystems of our country highlight current impacts that overall communities are facing with increased risks of exposure and uptake to cyanotoxins. Research needs encompass the expansion of studies at all aspects due to the uprising of these cyanotoxins and reinforces the urgent need of increasing the frequency of surveillance to achieve tangible effects of cyanotoxins in Portugal to ultimately implement regulations on cylindrospermopsins, anatoxins and saxitoxins worldwide.


This paper presents a tracking filter of radar beacon system (RBS) for automatic takeoff and landing of an unmanned aerial vehicle. The proposed tracking filter is designed as the decoupled tracking filter to reduce the computational burden. Also, an adaptive estimation method of the measurement error covariance is proposed to provide an improved tracking performance compared to the conventional decoupled tracking filter whenever the accuracy of RBS observations is degraded. 100 times Monte Carlo runs performed to analyze the performance of the proposed tracking filter in case of normal operation and degraded operations, respectively. The simulation results show that the proposed tracking filter provides the improved tracking accuracy in comparison with the conventional decoupled tracking filter.


Nowadays, micro blogs have become the most used tools for users to share many things: from just updating things to telling their conditions or thoughts. Some popular micro blogs mostly used to give comments and opinions are facebook, instagram, and twitter . Twitter has 259 million active users each month as for January until April 2017. This made twitter one of the best micro blogs to know the most updated opinions. The system uses Naive Bayes Classification to classify opinions about smartphone and computer from twitter. The sentiments are divided to positive, neutral, and negative. After that, Confusion Matrix is used to evaluate the algorithm and count the accuracy. Naive Bayes Classification gives 77.7% accuracy for Unigram, 50.7% for Bigram, and 31.7% for Trigram


Recently a novel scheme, based on an iterative decambering approach, was developed at NC State University for the prediction of post-stall characteristics of wings using known section data as inputs. The scheme, suitable for implementation in lifting-line and vortexlattice methods (VLM), differs from earlier approaches in the procedure for computing the residual for the Newton iteration. This paper presents an improvement to the decambering approach in which, superposition of lift distributions is used for computing the Jacobian and residual for the Newton iteration. With this improvement, basic and additional lift distributions are first pre-computed and stored. This information is subsequently used in the post-stall computations without the need for VLM in the iterative computations. As a result, the efficiency of the computations is increased and the post-stall computations can be done without the restriction of having a VLM in the loop. I. Introduction The ability of linear aerodynamic methods such as lifting-line theory (LLT), Weissinger's method, and vortex-lattice methods (VLM) to successfully predict the lift and induced drag behavior of medium to high aspect ratio wings is well established. In these methods, a linear lift curve with a slope of approximately 2� per radian is typically assumed for the airfoil sections that form the wings. For several decades, researchers have sought to extend the capability of these linear prediction methods to include the aerodynamic analysis of wings with nonlinear airfoil lift curves. These efforts were motivated by the desire to predict stall and post-stall aerodynamic characteristics of wings using experimental or computational aerodynamic data for the airfoil sections at post-stall conditions. It is recognized that the flow over a wing at post-stall conditions is highly three dimensional and the use of a quasi-two-dimensional approach represents a significant approximation. The impetus for such a prediction method, however, is provided by the need for rapid aerodynamic prediction capabilities for such high-alpha conditions for aircraft stability and control, simulations, and in the early phases of vehicle design. Furthermore, even high-order computational fluid dynamics (CFD) techniques are only now approaching the stage where they can be reliably used for high-alpha aerodynamic prediction. These CFD high-alpha analyses, however, require massive computing resources and significant time for analysis at even a single angle of attack. Thus the search for rapid, albeit approximate, approaches for stall and post-stall prediction of wings using known section data continues to be of interest. The traditional approaches for extending linear aerodynamic prediction methods to handle nonlinear and post-stall airfoil lift curves can be broadly classified into two kinds: the iterative -distribution approach and the �-correction approach. In the first approach, a lift distribution is first assumed on the wing. The distribution is then iteratively corrected by determining the effective-� distribution using the nonlinear airfoil lift curve. In the second approach, the deviation of the airfoil nonlinear lift curve from the potential-flow !


For centuries Kashmir was the home of the great Sanskrit scholars and luminaries, who were not only revered in the valley but accepted as authorities outside as well. One great Indian religion, Saivism, has found some of its most eloquent teachers on the bank of the Vitasta. Kalhanaand his followers has given a wide picture of theological literary activities through the great works who flourished long before and who thought and wrote with ability on different branches of literature. Ancient Kashmir literature itself has given a wide picture of literary activities through the great works who flourished long before and who thought and wrote with ability on different branches of literature. Through this paper I will highlight the great ancient theological works of valley.


To help transportation planners, the Federal Highway Administration (FHWA) has recently sponsored the development of a sketch planning analysis tool for estimating the benefits and costs of intelligence transportation system (ITS) deployment. Called the ITS Deployment Analysis System (IDAS), the tool was developed by Cambridge Systematics for FHWA and operates as a postprocessor to traditional planning models that are based on the four-step planning process. IDAS was used to predict the likely benefits of deploying ITS in Chittenden County, Vermont, a medium-sized region in northwestern Vermont, to gain insight into IDAS' applicability in evaluating ITS benefits. A sensitivity analysis was also conducted to assess the sensitivity of IDAS' results to the choice of values of some of the model's parameters. The sensitivity analysis demonstrates that some of the model's parameters tend to have a more significant impact on the results than others. Finally, the results indicate that, for medium-sized areas similar to Chittenden County, coordination of signals along major arterials and transit projects for automatic vehicle location and scheduling appear to be more cost-effective than freeway and incident management systems.


The amount of aluminium which can be evaporated from a graphite crucible is greatly increased if silicon is first evaporated. A small low-power aluminium source is described which utilizes this fact. So far more than 2.5 g of aluminium have been evaporated without apparent damage to the source.


In accordance with the problems of V-type stepped spillway running under circumstance of large discharge per unit width,hydraulic characteristics of V-type stepped spillway with slope of 1∶2,such as flow pattern,time average pressure and energy dissipation ratio,are studied under different discharge per unit width.The test results show that the vortex strength is different with its location on the same step;the more close to the central axis,the smaller the vortex strength is;on the horizontal plane of certain step,most of the negative pressure zones are located near the concave corner of the side walls while none near the central axis;on the vertical plane,the largest time average pressure is located near the concave corner;the energy dissipation ratio is higher and application scope of V-type stepped spillway is wide.


Cervical cancer remains a leading cause of cancer death in many low- and middle-income countries. Key issues that must be addressed include the obstacle of poverty, the importance of community representatives, and the credibility of the medical establishment. Better understanding of the complex layers of social ecology and the social determinants of health will allow public health planners to build sustainable programs.


The solution-refined method is developed to solve electrostatic fields of the electron-beam direct-write lithography system. The prediction of accurate electron trajectories and the geometry of the developed photoresist patterns rely on high-resolution electrostatic fields in the whole system. Considering fabrication errors, such electrostatic fields cannot be solved using a cylindrical symmetry. Thus, this problem is a multiscale problem that requires a huge computer memory to solve. In our cases, the minimum number of grids of 1 nm length are applied and the total memory required approaches 75 Gbyte. Since the proposed solution-refined technique has a tradeoff with computational time, fewer central processing units (CPUs) are needed to solve this system because each CPU that solves the problem exceeds its available storage memory. The proposed technique can be used to solve the electron-beam direct-write lithography system at higher resolution and the problems exceed the available storage memory.


: Natural disasters related to the agriculture sector frequently occur in China. This article studied the prevention and control of drought and flood in agricultural lands and the optimization method of planting structures to avoid disaster. Firstly, the impact of the change of input structure on the prevention and control of drought and flood disasters of agricultural lands was analyzed, and the evaluation system of input-output efficiency was constructed. Secondly, the evaluation model was built using the DEA (Data Envelopment Analysis) method to provide the theoretical basis for the quantitative evaluation of input-output efficiency. Taking Jiangxi Province as an example, the input-output data of drought and flood control of agricultural land in twenty cities in 2014-2017 was analyzed. The results show that the input-output efficiency of 80% of farmland in Jiangxi Province is low, and drought and flood prevention resources are not sufficiently utilized. In addition, the low pure technical and scale efficiency are the main reasons for the low input-output efficiency of drought and flood prevention. The effect of human and financial input in drought and flood prevention of farmland in Jiangxi Province is slightly different for value output and actual output. From the aspects of strengthening the investment in basic facilities and the technical research and development of agricultural products, the optimization strategy for the input structure of drought and flood prevention of agricultural land is put forward.


Over the past decade, organic solar cells (OSCs) have received wild attention in scientific community and have been considered one of the most important sources of low-cost electricity production. Recently, OSCs based on star-shaped small molecular (SM) non-fullerene acceptors (NFAs) have developed rapidly, and the highest power conversion efficiency (PCE) has exceeded 10%. The star-shaped SM NFAs not only have three-dimensional charge transport characteristics similar to fullerenes, but also have strong light absorption capacity and easy tunable energy levels. They are potential candidates as outstanding acceptor materials. In this paper, the research progresses of star-shaped SM NFAs OSCs have reviewed in a targeted manner. Moreover, the influence of molecular structure, central unit and peripheral linking group on OSC performance has been evaluated systematically. We hope this article can stimulate inspiration for designing higher performance OSCs acceptor materials in the future.


Carbon footprint optimization (CFO) is important for sustainable heavy-duty e-truck transportation. We consider the CFO problem for timely transportation of e-trucks, where the truck travels from an origin to a destination across a national highway network subject to a deadline. The goal is to minimize the carbon footprint by orchestrating path planning, speed planning, and intermediary charging planning. We first show that it is NP-hard even just to find a feasible CFO solution. We then develop a $(1+\epsilon_F, 1+\epsilon_\beta)$ bi-criteria approximation algorithm that achieves a carbon footprint within a ratio of $(1+\epsilon_F)$ to the minimum with no deadline violation and at most a ratio of $(1+\epsilon_\beta)$ battery capacity violation (for any positive $\epsilon_F$ and $\epsilon_\beta$). Its time complexity is polynomial in the size of the highway network, $1/\epsilon_F$, and $1/\epsilon_\beta$. Such algorithmic results are among the best possible unless P=NP. Simulation results based on real-world traces show that our scheme reduces up to 11\% carbon footprint as compared to baseline alternatives considering only energy consumption but not carbon footprint.


We describe a patient with Berger's disease and polyarteritis nodosa. This association has not been described previously in the literature. A causal relationship between the two diseases is suggested.


This study aims to carry out some considerations about the changes that took place in music during the late 16th and early 17th centuries. We discuss Humanism as an intellectual, philosophical, and artistic movement, as well as its consequences in the way art was produced and in the techniques that express these changes. Painting and literature serve as theoretical frameworks for the introduction of elements that help to understand more specific changes in the field of music, particularly the change in texture. Some studies in the field of cognition are also considered, so as to determine fundamentals of perceptual psychology that may justify such changes in musical texture.


Bounds compression for fat pointers can reduce the memory and performance overhead of maintaining pointer bounds and is necessary for efficient hardware implementation. However, compression can introduce inaccuracy to the bounds, making certain out-of-bounds accesses undetectable. Although the security threat can be mitigated by padding the objects, no known mitigations can detect these out-of-bounds accesses deterministically. We present MIFP, a method that automatically mixes both compressed and uncompressed bounds to preserve the performance benefits of bounds compression while ensuring accurate bounds checking. Given a program using a single fat pointer representation (e.g., all compressed bounds), MIFP performs whole-program analysis to expand potentially unsafe and inaccurate fat pointers such that they carry accurate uncompressed bounds. To minimize the number of pointers to expand, MIFP adds instrumentation on a per-allocation-site granularity; objects of the same type but different code allocation locations can have their pointer members transformed differently depending on how the pointers are used. We describe our algorithm and supporting data structures, and show that utilizing multiple fat-pointer representations reduces the runtime and memory overheads of uncompressed bounds by 79% and 93% respectively.


If Γ is a graph, with distinguished vertex *, let A(Γ) denote the non-commutative path algebra on the space of semi-infinite paths in Γ beginning at *. We discuss embeddings A(Γ1) → A(Γ2) of AF algebras associated with graphs Γ1 and Γ2 from a dimension group point of view. For certain infinite T-shaped graphs, we have K0(A(Γ)) ≅ ℤ [t], with positive cone identified with {0}∪ {P ∈ ℤ [t]: P (λ) > 0, λ ∈ (0, γ]}, where γ = γ (Γ) =||Γ||−2 where denotes the ideal generated by a polynomial Q=Q(Γ) which is essentially the characteristic polynomial of the graph Γ and positive cone identified with {0}∪ {f + : f(γ) > 0} where γ = γ(Γ) = ||Γ||-2. Hence there exists a unital homomorphism A(Γ1) → A(Γ2) if ||Γ1|| = ||Γ2||, and Q(Γ2) divides Q(Γ1). The structure of K0(A(Γ)) as an ordered ring is related to the fusion rules of rational conformal field theory.


Acute rejection (AR) in renal transplantation is an established risk factor for reduced allograft survival. The incidence of AR is 10-20% despite standard of care immunosuppression, suggesting molecular pathways exist which are inadequately suppressed by current therapy. Molecules with regulatory control among these could serve as important targets for therapeutic manipulation to prevent rejection. Here, an integrative network-based computational strategy incorporating gene expression and genotype data of human renal allograft biopsy tissue was applied, to identify the master regulators- the key driver genes (KDGs)- within dyregulated AR pathways. A 982 meta-gene signature with differential expression in AR versus non-AR, was identified from a meta-analysis of microarray data from 735 human kidney allograft biopsy samples across seven data sets. Among the upregulated genes, enriched biologic processes include the immune response, leucocyte activation and antigen processing and presentation; where monocytes, macrophages and dendritic cells were identified as the major immune cell populations. Genomic key driver analysis of this signature predicted 14 KDGs. Expression of the KDGs provided risk stratification for subsequent graft loss with high prediction accuracy at 2 years post transplant (AUC=0.913) and 2 years post biopsy (AUC=0.889) in separate clinical cohorts. Interrogation of two drug-repositioning resources identified compounds with predicted efficacy against individual KDGs or a key driver-based gene set respectively, and therefore be repositioned for AR prevention. Minocycline, an FDA-approved tetracycline antibiotic, was chosen for experimental validation in a murine cardiac allograft model of AR. Minocycline alone attenuated the inflammatory profile of AR compared with controls, and when co-administered with immunosuppression prolonged graft survival. This study demonstrates the proof-of-concept that a network-based strategy, using gene expression and genotype data assists target prioritization for therapeutics in renal allograft rejection.


The Laugier-Hunziker syndrome is an acquired disorder characterized by macular hyperpigmentation of the oral mucosa and lips, often associated with longitudinal melanonychia. It is not associated with systemic manifestations or malignancies and knowledge of it is important in the differential diagnosis of mucocutaneous hyperpigmentation, a common fi nding in clinical practice. We report a case of a 56 year-old patient, whose diagnosis was based on clinical and histopathological fi ndings and the absence of polyps at colonoscopy.


The soybean is one of many foods known to contain potentially goitrogenic substances. The effects of these goitrogens may be diminished by processing of the bean, or eliminated by addition of iodide to the diet.
 In view of the paper in this issue of Pediatrics on the goitrogenic effect of a soybean milk used in infant feeding, it is important to report our previously unpublished results with Sobee®. Though Sobee® is a soybean preparation it is not goitrogenic as measured by an increase in the relative weights of the thyroid gland in rats.


The case is reported of a 56‐year‐old female who over 18 months developed a symmetrical eruption of hundreds of bluish‐red papules, a small number of which have spontaneously resolved. The clinical and histopathological findings were compatible with the diagnosis of generalized eruptive histiocytoma. The ultrastructural findings in this case suggest that this condition which is in the non‐X group of histiocytic disorders is closely related to histiocytosis X.


The front film compensated reflective liquid crystal display device was studied in normally black and normally white operation conditions using a dynamic parameter space method. The electro-optical response and reflectance spectra were also studied for different operation modes. We show that high quality normally white or normally black modes can be obtained by placing the fast axis of a quarter wave plate at 45° or 0° to the input director direction. The viewing angle characteristics of the optimum modes are wide and symmetrical.


Research the two-wheeled self-balancing car control optimization problem.For two-wheeled vehicles are of instability,nonlinear,strong coupling and other characteristics,and unable to establish its mathematical model accurately.It is difficult for traditional control theory to meet actual control requirements well.In order to solve the problem of two-wheeled vehicle high-speed stable operation,on the basis of considering the characteristics of the controlled object and combining the practical engineering application,we established a system dynamics model and analyse the characteristic,put forward the Fuzzy-PI composite control scheme which designs the fuzzy controller and PI controller on the angle and speed of the car.By the vehicle's speed control simulation experiment and anti-jamming characteristic simulation experiment,the simulation results show that the designed fuzzy-PI controller can guarantee the two-wheeled self-balancing vehicle high-speed and stable operation.This method is of strong anti-interference,good dynamic quality,and simple structure,easy implementation,has good engineering practical value.


The development of applications for high-performance embedded systems is typically a long and error-prone process. In addition to the required functions, developers must consider various and often conflicting non-functional application requirements such as performance and energy efficiency. The complexity of this process is exacerbated by the multitude of target architectures and the associated retargetable mapping tools. This paper introduces an As-pect-Oriented Programming (AOP) approach that conveys domain knowledge and non-functional requirements to optimizers and mapping tools. We describe a novel AOP language, LARA, which allows the specification of compi-lation strategies to enable efficient generation of software code and hardware cores for alternative target architectures. We illustrate the use of LARA for code instrumentation and analysis, and for guiding the application of compiler and hardware synthesis optimizations. An important LARA feature is its capability to deal with different join points, action models, and attributes, and to generate an aspect intermediate representation. We present examples of our aspect-oriented hardware/software design flow for mapping real-life application codes to embedded platforms based on Field Programmable Gate Array (FPGA) technology.


Margaret Phillips, age 83, develops software applications for her employer. More than thirty-five years ago the organization Experience Works was launched as a demonstration project to show that older, and often poor, farmers could continue to use their abilities, their "green thumbs," to beautify America's parks and highways. That is how the organization got its original name, Green Thumb. Over the years, that initial project developed into the most successful federal training and employment program for low-- income older people, the Senior Community Service Employment Program (SEP), funded under Title V of the Older Americans Act. SCSEP helps thousands of low-income individuals by providing the training and experience they need to secure employment and helping them supplement their incomes while they are being trained. Now, Green Thumb is called Experience Works (the name was changed last year), and is the largest organization in the country dedicated to providing training and employment services to older individuals. Besides on-the-- job training, Experience Works also provides a wide variety of computer skills and technology training services and other job-related training programs. In recent years, we have added additional services such as Experience Works Staffing Services, the only national staffing service focused on the employment needs of older workers. Also, we launched Geezer.com, a website that provides older artisans and craftspeople a nationwide market for their unique handcrafted goods. Finally, in 1998, we introduced the Experience Works Prime Time Awards Program, an annual effort to recognize the contributions of older workers at the local, state, and national level. All of our services allow the organization's more than 500 employees the privilege and opportunity to be inspired by the tremendous contributions that older individuals make to our society. Yet, of all the examples I have seen of elders who have shown that ability is truly ageless, the most striking is the Prime Time Awards Program. Since 1998, we have honored outstanding older workers from all fifty states, Puerto Rico, and the District of Columbia. In addition, we select one individual each year to represent America's oldest worker. Just a sampling of the stories from these remarkable individuals shows the tremendous contributions older people are making as workers into their 70s, 80s, and even 90s. For example, 84-year-old Richard Wolf, who after one forty-five-year career with International Harvester, started another career in social services. At age 70 he earned two Bachelor of Arts degrees in human services, education, and psychology and now works at Hospice House, where he coordinates the schedules of the thirtyfive volunteers who assist at the unit, answer phones, and generally solve problems and provide emotional support and practical assistance to families and staff. Colleagues say he brings an amazing degree of enthusiasm and love for life. Or take Velma Bailey, who in 1988 came to the Sun City, Arizona, Boswell Memorial Hospital as a food-service worker, providing nourishment preparing and delivering food trays to patients throughout the day. Now, at age 93, Bailey works thirty-two hours a week and has had a perfect attendance record for the past ten years. In addition to holding down her job, she maintains a busy social schedule that includes quilting with a church group, games night with neighbors to play rummy and dominoes, and a Friday-night knitting group at a nearby recreation center. Then there is 83-year-old Margaret Phillips. At a time when most people start thinking about slowing down, Phillips was just getting started. Thirty years ago she began a career at Ball State University as a part-time secretary in the School of Music. She became a certified professional secretary and worked her way up the ladder to business manager in the office of the dean. At age 65, she discovered an aptitude for work with computers and constantly updates her skills with university computer science classes. …


Termite Damage Percentage(TDP) and Termite Damage Index(TDI) were used in termite damage investigation for further understanding of termite damage to trees in urban forest.Termite damage investigation and evaluation were carried out by using these indexes during winter and early spring in Nanjing Area.The results showed that the most commonly damaged tree species with higher TDPs were ranked in the descended order as follows: Cupressus lusitanica 'Zhongshanbai'(90.2%),Ligustrum lucidum(88.4%),Cinnamomum camphora(69.4%),Larix gmellini(69.2%),Platanus acerifolia(65.4%),Robinia pseudoacacia(60.0%),Magnolia grandiflora(52.8%),Metasequoia glyptostroboides(50.1%),Liriodendron chinense and L.chinense×tulipifera(50.0%) and heavily damaged tree species with higher TDIs were ranked in descended order as follows: Robinia pseudoacacia(0.503),L.lucidum(0.319),Quercus glandulifera and Q.acutissima(0.290),Cinnamomum camphora(0.213),L.chinense and L.chinense×tulipifera(0.185),C.lusitanica 'Zhongshanbai'(0.124),M.grandiflora(0.150),Populus sp.(0.126),Taxodium ascendens(0.112),M.glyptostroboides(0.100),L.gmellini(0.086),P.acerifolia(0.056).The slightly damaged tree species were listed as follows: Pterocarya stenoptera,Celtis tetrandra,Pteroceltis tatarinowii,Melia azedarach,Pinus taeda,Cryptomeria fortunei,Cedrus deodara,P.massoniana,Ulmus sp.,P.thunbergii etc.It was found that the termite damage to urban forest trees in Ziin Mountain area,Nanjing was significantly influenced by the soil conditions,age and health of trees.


1. Introduction. 2. Access to the courts and court information. 3. Contempt of court. 4. Reporting restrictions. 5. Tribunals. 6. Government secrecy and reporting. 7. Public access to information. 8. Election reporting. 9. Dealing with libel claims. 10. Obscenity, race and religion. 11. Journalists' sources. 12. Breach of confidence. 13. Copyright and related Rights.


Protective effects for adult neurological disorders have been attributed to sex hormones. Using a murine model of prematurity, we evaluated the role of estrogen signaling in the process of perinatal brain injury following exposure to intrauterine inflammation.


In Beilun estuarine area of Guangxi,China,the intertidal flat were filled to an elevation of about 220cm Yellow Sea Datum to mix-culture Avicenniamarina(AM)seedlings with four species of saltmarsh,aimed at studying the effect of biological prevention method for reducing the fouling damage on mangrove trees.The results showed that Cyperus malaccensis(CM)and Zoysia matrella(ZM)were able to grow and spread faster,and more efficient to slow down water velocity and accelerate sedimentation than Scirpus validus var.laeviglumis(SV)and Phragmites australis(PA).19species of fouling fauna were found on saltmarsh and mangroves,among which Balanus littoralis,Euraphia withersi,Littorina melanostoma and L.scabra were major dominant species.Among four saltmarsh species,the fouled degrees on CM and ZM were significantly less than those on other two species.And the fouled degrees on four saltmarsh species were all significantly less than that on A.marinatree.The mix-culturing of saltmarsh CM or ZM with mangrove tree AM could efficiently reduce the fouling damage,resulting in better tree growth indexes i.e.tree height,leaf number,branch number,branch conservation and survival rate than those in mono-species treatment areas.In general,a saltmarsh-mangrove cooperating ecological conservation system could be a practical model for mangrove afforestation.


Objective To investigate the methods and advantages of total laparoscopic hysterectomy(TLH) with EREB electrosurgery station.Methods 264 cases of TLH using EREB electrosurgery station were analyzed retrospectively.The average age of the patients was 48.5 years old(40~67).Of the 264 cases,188 cases had uterine myoma,44 cases had adenomyosis,1 case had refractory dysfunctional uterine bleeding,13 cases had atypical endometrial hyperplasia,86 cases had history of surgery on lower abdomen.Results Operations were completed successfully in all 246 cases.2 cases who had history of surgery on lower abdomen and severe pelvic adhesions were conversed to open surgery.1 case was found bladder perforation which was repaired by laparoscopic operation.2 cases who had ureteral-vagina fistula after surgery were cured by setting double-J tube with ureteroscope.Conclusion TLH with EREB electrosurgery Station is a safe,reliable procedure to remove uterus.


Using web development tools such as asp.net and C#,the authors develop a web-based system of teacher's quantification check.In this system,teaching and research requirements in the process of check are analyzed,the frame and database of the system are designed,and finally the WEB is realized.


s To improve the performance of carbon nanofibers as electrode material in electrical double-layer capacitors (EDLCs), we prepare three types of samples with different pore control by electrospinning. The speciments display different surface structures, melting behavior, and electrochemical performance according to the process. Carbon nanofibers with two complex treatment processes show improved performance over the other samples. The mesoporous carbon nanofibers (sample C), which have the optimal conditions, have a high sepecific surface area of 696 m 2 g − 1 , a high average pore diameter of 6.28 nm, and a high mesopore volume ratio of 87.1%. In addition, the electrochemical properties have a high specific capacitance of 110.1 F g − 1 at a current density of 0.1 A g − 1 and an excellent cycling stability of 84.8% after 3,000 cycles at a current density of 0.1 A g − 1 . Thus, we explain the improved electrochemical performance by the higher reaction area due to an increased surface area and a faster diffusion path due to the increased volume fraction of the mesopores. Consequently, the mesoporous carbon nanofibers are demonstrated to be a very promising material for use as electrode materials of high-performance EDLCs.


265 - 269 ( 2021 ) A case of clinical1y unsuspected nonspecific inflammatory aortic regurgitation is reported. A 69-year-old female patient underwent aortic valve replacement for aortic regurgitation. Pathological examination of resected aortic valve showed abscess formation and inflammatory granulation tissue in the non-coronary cusp. Therefore, we diagnosed nonspecific inflammatory aortic regurgitation. It is generally considered that the use of prednisolone for vasculitis syndrome is effective ; however, for nonspecific inflammatory aortic regurgitation its use has not been established. Prednisolone treatment could be an option for nonspecific inflammatory aortic regurgitation. Jpn. J. Cardiovasc. Surg. 50 : 265 - 269 ( 2021 )


We present the results of a detailed investigation of the prompt and afterglow emission in the H.E.S.S. detected GRB 190829A. Swift and Fermi observations of the prompt phase of this GRB reveal two isolated sub-bursts or episodes, separated by a quiescent phase. The energetic and the spectral properties of the first episode are in stark contrast to the second. The first episode, which has a higher spectral peak $\sim 120 \keV$ and a low isotropic energy $\sim 10^{50}\erg$ is an outlier to the Amati correlation and marginally satisfies the Yonetoku correlation. However, the energetically dominant second episode has a lower peak energy and is well consistent with both the correlations. We compared this GRB to other low luminosity GRBs. A fundamental correlation predicts a duration that makes the first episode consistent with a shock breakout. Additionally, peculiar central engine activities are observed during the afterglow phase. This includes a long-lasting flare in X-rays and optical emission that requires the central engine to be active for a long duration ($\sim 10^4 \s$). We analyzed the late time Fermi-LAT emission that encapsulates the H.E.S.S. detection. Some of the LAT photons are likely to be associated with the source and might have inverse Compton origin as seen in previously detected TeV-GRBs. All the above observational facts suggest GRB 190819A is a peculiar low luminosity GRB that is initially powered by shock breakout followed by central engine activities. Furthermore, our results show that TeV energy photons seem common in both high and low luminosity GRBs.


Objectives: To examine the effect of galantamine on activities of daily living (ADLs) with respect to baseline dementia severity, correlation with cognitive and global function, specific ADLs affected, and maintenance of ADL independence.


ity of cryotherapy: a systematic literature review. Available at: http://www.path .org/files/RH_cryo_white_paper.pdf. Accessibility verified October 5, 2005. 22. Cox JT. Management of cervical intraepithelial neoplasia. Lancet. 1999;353: 857-859. 23. Samson SL, Bentley JR, Fahey TJ, McKay DJ, Gill GH. The effect of loop electrosurgical excision procedure on future pregnancy outcome. Obstet Gynecol. 2005; 105:325-332. 24. Goldie SJ, Kuhn L, Denny L, Pollack A, Wright TC. Policy analysis of cervicalcancer screening strategies in low-resource settings: clinical benefits and cost effectiveness. JAMA. 2001;285:3107-3115. 25. Crum CP. The beginning of the end for cervical cancer? N Engl J Med. 2002; 347:1703-1705. 26. Skjeldstad FE, Koustsky L; for the Merck Phase III HPV Vaccine Steering Committee (FUTURE II). Phase III trial of prophylactic quadrivalent HPV 6, 11, 16, 18 L1 virus-like particle (VLP) vaccine: prevention of cervical intraepithelial neoplasia (CIN) 2/3 including adenoand squamous-cell carcinoma in situ (CIS). Presented at: Infectious Diseases Society of America Late Breaker Session 66, LB-8a; October 7, 2005; San Francisco, Calif. 27. Blumenthal PD. Immunization against cervical cancer: Who? When? Where? Available at: http://www.medscape.com/viewarticle/444979. Accessibility verified October 5, 2005.


Remittances can affect child nutrition in two main ways, through increased income from remittances and changes in time allocation within the household. It is not theoretically apparent how a parent migrating and sending back remittances will affect child nutrition. Any added income will likely improve child nutrition by relieving any household income constraint, while the loss of a parent or other adult may reduce the time available to prepare food and care for the child. This study uses data from Peru to find that to 3000 Soles in remittances will make up for a parent not being in the household. Acknowledgements I would like to thank my advisor, Amy Damon, for her help on this project, as well as readers Karine Moe, Gary Krueger and Alicia Johnson, as well as honors teacher Raymond Robertson.


In network security protocols, the freshness and uniqueness of a particular protocol-run provide a strong defense against replay attacks. These two properties are incorporated into a protocol interaction by the use of time-variant parameters such as nonces, random numbers, sequence numbers and timestamps. Many of the network authentication protocols can be classi ed into two main streams by the type of time-variant parameter they use; nonce or timestamp. Network authentication protocols based on timestamps are always more e cient in terms of numbers of rounds to their nonce-based counterparts. However, regardless of this favorable operational characteristic, most widely used protocols favor nonce-based schemes over timestamps. The main reason for this neglect of timestamp-based schemes was the di culty of establishing synchronized clocks over a widely distributed network in-


The refined Stirling numbers of the first kindnm0m1 ··· mk?1 specify the number of permutations of n indices possessing mi cycles whose lengths modulo k are congruent to i, i=0,1,2,?,k?1. The refined Stirling numbers of the second kindnm0m1 ··· mk?1 are similarly defined in terms of set-partitions and the cardinalities of their disjoint blocks. Generating functions for these two types of refined Stirling numbers are derived using the Faa di Bruno formula. These generating functions allow the derivation of recurrence relations for both types of refined Stirling numbers.


The third molars are the toughest, far-most and wide when compared to the other teeth and helps in grinding of food inside the oral cavity of the individual he most commonly impacted teeth in the human dentition is the third molars. Due to the impaction of the third molars, the oral and maxillofacial surgeons often extract the third molars by a surgical procedure. A planned surgical procedure is to be followed by the surgeons to minimize any complications related to the third molar extraction. The primary goal of this research was to review the literature related to complications after the third molar surgery. Data was extracted from the online databases like Medline and Pub Med Central, and tabulated using the pre-designed data extraction forms. Commonly the extractions are done by the general dentists using the forceps and elevator. In case of the tooth that is near a major nerve, with large or curved roots, in fusion with the jawbone or if it's nearby a crown or fillings the Dento alveolar surgery is recommended. These complications can affect the quality of life of the patient. In present time the knowledge and awareness about oral health and its impact on the quality of life is understood and maintained. The patient should be made aware about all the possible complications before the surgery.


In the above article [Liu H, Stresser DM, Michmerhuizen MJ, Li X, Othman AA, Reed AD, Schrimpf MR, Sydor J, and Lee AJ (2018) Drug Metab Dispos April 2018, 46(4):429-439; DOI: https://doi.org/10.1124/ dmd.117.077511], the unit for CLint in Table 4 on Page 437 and text on Page 436 (under the sections of "Metabolism of ABT-126 with cDNA-Expressed Cytochrome P450 and FMO Enzyme" and "Metabolism of ABT-126was with cDNA-Expressed UGT Enzymes") was incorrect. The units should be mL/min per milligram protein instead of mL/min per milligram protein.


To improve the Natto flavor, in this experiment, different ratios between black soybean and soybean as raw materials were used to explore the suitable fermentation conditions for Natto producing. The results of orthogonal test show that the best condition is: the ratio of black soybean to soybean is 1:4, boiling for 30 min, Bacillus natto inoculation amount 10%, fermentation temperature 38°C and fermentation time 13 h.


The Yellow River Basin has been affected by global climate change. Studying the spatial–temporal variability of the hydrothermal climate conditions in the Yellow River Basin is of vital importance for the development of technologies and policies related to ecological, environmental, and agricultural adaptation in this region. This study selected temperature and precipitation data observed from 118 meteorological stations distributed in the Yellow River Basin over the period of 1957–2015, and used the Mann–Kendall, Pettitt, and Hurst indices to investigate the spatial–temporal variability of the hydrothermal climate conditions in this area. The results indicated: (1) the annual maximum, minimum, and average temperatures have increased. The seasonal maximum, minimum, and average temperatures for the spring, summer, autumn, and winter have also increased, and this trend is statistically significant (p < 0.01) between 1957–2015. The rate of increase in the minimum temperature exceeded that of the maximum temperature, and diurnal warming was asymmetric. Annual precipitation and the total spring, summer, and autumn precipitations declined, while the total winter precipitation increased, although the trend was non-significant (p > 0.05). (2) Based on the very restrictive assumption that future changes will be similar to past changes, according to the Hurst index experiment, the future trends of temperature and precipitation in the Yellow River Basin are expected to stay the same as in the past. There will be a long-term correlation between the two trends: the temperature will continue to rise, while the precipitation will continue to decline (except in the winter). However, over the late stage of the study period, the trends slowed down to some extent.


Purpose of study: Female breast cancer is the second leading cause of cancer death in U.S. women, and the incidence of new breast cancer cases continues to increase. Despite slightly lower breast cancer incidence rates among African American (AA) compared to European American (EA) women in the U.S., AA women experience significantly higher breast cancer mortality. To better understand the extent to which environmental and genetic factors might help explain higher mortality rates among AA women, we examined the association between a measure of exposure to chemical pollutants and genomic profiling with breast cancer mortality among women with breast cancer in North Carolina. Procedures: Using a molecular epidemiologic approach, we examined the association of county hog concentration (a marker of environmental exposure to chemical pollutants) and genomic variations identified via targeted exome sequencing with age-adjusted breast cancer mortality rates among 146 women in North Carolina, stratified by race (AA vs. EA). The odds of breast cancer-specific mortality were estimated as a function of county hog concentration quintiles. Results: Overall, breast cancer mortality among AA women was higher than among EA women (OR=1.4, p Conclusions: Our findings suggest that living in a county with a high concentration of hogs may increase breast cancer mortality risk among AA women, and the high frequency of CNVs varies by race; both CNV and county hog concentration may contribute to racial disparities in breast cancer mortality among AA and EA women in North Carolina. Citation Format: Jung S. Byun, Sean Lee, Sijung Yun, Eliseo J. Perez-Stable, Anna M. Napoles, Paul Strickland, Kevin L. Gardner. Race, copy number variation, and local hog concentration in breast cancer mortality [abstract]. In: Proceedings of the Annual Meeting of the American Association for Cancer Research 2020; 2020 Apr 27-28 and Jun 22-24. Philadelphia (PA): AACR; Cancer Res 2020;80(16 Suppl):Abstract nr 1183.


The optical absorption in thin films of electrochromic oxides of tungsten and molybdenum has over the solar spectral range at temperatures from about 100 K to 365 K. The films were depos at room temperature by RF plasma enhanced chemical vapor deposition and then converted to th injection compounds LixWO3 and LixMoO3 by reaction with n-butyl lithium in a water-free an environment to duplicate their colored elctrochromic state. The optical absorption in the LixW03 films consists of a broad peak centered near 1.7 eV. The Absorption in the LixMo03 films consists of a broad band centered near 1.3 eV, a temperature dependent Urbach band edge near 3 eV plus a very broad tailing absorption connecting these two features. The optical absorption in these materials in interpreted in terms of a small polaron absorption process and temperature dependent structual disorder.


X-ray flares are frequently detected in the X-ray afterglow light curves and are highly correlated with the prompt emission of gamma-ray bursts (GRBs). We compile a comprehensive sample of X-ray flares up to 2021 April, comprising 697 flares. We classify the total sample into four types: early flares (tp≤103 s), late flares (tp>103 s), long gamma-ray burst (LGRB) flares and short gamma-ray burst (SGRB) flares, and analyze the distributions and relationships of the flare parameters. It is found that the early flares have a higher frequency, shorter duration, and more asymmetrical structure. In addition, the distributions of the morphological parameters of the SGRB flares are similar to those of the LGRB flares. We also find that the durations and rising (decay) times of the early flares are positively correlated with the peak times, but the late flares follow the different dependent relations. There is a strong anti-correlation between the peak luminosities (LX,P) and the peak times of the flares, e.g., LX,p∝tp,z−1.45 for the LGRB flares, and LX,p∝tp,z−1.27 for the SGRB flares, respectively. Furthermore, the peak luminosity is highly dependent on the isotropic energy (EX,iso) for the early LGRB flares, the best fit is LX,p∝EX,iso1.06(r=0.89). We also find a tight three-parameter correlation, LX,p∝tp,z−1.03EX,iso0.92(r=0.96). All the late flares fall into the 3σ confidence region defined by the early flares. In terms of the point of kinematic arguments, both the SGRB and LGRB flares support a common scheme of internal origin. The SGRB flares have similar properties to the LGRB flares, suggesting that both of them share a similar physical mechanism from the late-time activity of central engine.


Warehousing as logistics function generates different specific activities. Related to this, some of these activities can be possible sources of different kinds of danger, depending on the type and quantity of inventories (goods), technologies, applied equipment, environment, human factors etc. In the palletized goods warehousing domain, selective pallet racks represent typical technology, which has been multiple confirmed and is widely spread. However, the racks themselves (although they are typically statically elements) might be the source of possible danger. Their cause might occur in the phases of their design, construction, exploitation and control. This set of influences and dangers has resulted with introduction of new specific regulations in some of these areas. Having that in mind, the aim of this paper is to point out to some analysis directions and preventive activities related to the safety of pallet racks.


Background—The purpose of this study was to determine the influence of left ventricular (LV) hypertrophy and geometry on the diagnostic accuracy of wall motion and additional perfusion imaging during high-dose dobutamine/atropine stress magnetic resonance for the detection of coronary artery disease. Methods and Results—Combined dobutamine stress magnetic resonance (DSMR)-wall motion and DSMR-perfusion imaging was performed in a single session in 187 patients scheduled for invasive coronary angiography. Patients were classified into 4 categories on the basis of LV mass (normal, ⩽81 g/m2 in men and ⩽62 g/m2 in women) and relative wall thickness (RWT) (normal, <0.45) as follows: normal geometry (normal mass, normal RWT), concentric remodeling (normal mass, increased RWT), concentric hypertrophy (increased mass, increased RWT), and eccentric hypertrophy (increased mass, normal RWT). Wall motion and perfusion images were interpreted sequentially, with observers blinded to other data. Significant coronary artery disease was defined as ≥70% stenosis. In patients with increased LV concentricity (defined by an RWT ≥0.45), sensitivity and accuracy of DSMR-wall motion were significantly reduced (63% and 73%, respectively; P<0.05) compared with patients without increased LV concentricity (90% and 88%, respectively; P<0.05). Although accuracy of DSMR-perfusion was higher than that of DSMR-wall motion in patients with concentric hypertrophy (82% versus 71%; P<0.05), accuracy of DSMR-wall motion was superior to DSMR-perfusion (90% versus 85%; P<0.05) in patients with eccentric hypertrophy. Conclusions—The accuracy of DSMR-wall motion is influenced by LV geometry. In patients with concentric remodeling and concentric hypertrophy, additional first-pass perfusion imaging during high-dose dobutamine stress improves the diagnostic accuracy for the detection of coronary artery disease.