text:
Getting Cash For Your Junk Automobile
06 Feb 2018 14:05
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No Fuss adds two international events to Fort William programme
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Fort William will be the centre of attention again this October when the eyes of the mountain bike world focus on the Outdoor Capital of the UK.
No Fuss Events, the Fort William-based events company, has introduced two events to the calendar: the final round of The European Continental Enduro Series and The WEMBO World Solo 24-hour Championships.
On Tuesday January 16, the Enduro World Series (EWS) launched its new Continental Enduro Series. Round four, the final round of the 2018 European Continental Enduro Series, will be hosted at Nevis Range on October 13 and 14, staged by the No Fuss team.
In recent years, The Enduro World Series has changed the way mountain biking is perceived. The reputation of the World Series is global and has showcased some of the most incredible riding destinations in the world.
Chris Ball, director of the Enduro World Series, said: 'We're delighted Fort William will host the closing round of the new European Continental Enduro Series. The area is steeped in mountain biking history, thanks to the legendary Downhill Word Cup, so it's an honour to follow in their footsteps.
'We've worked with No Fuss Events before and know just how incredible their events are and look forward to seeing exciting racing on those iconic trails.'
The following weekend, October 20 and 21, sees the World Endurance Mountain Bike Organisation's (WEMBO) World Solo 24-hour Championships arrive in Fort William. This event was last staged at Nevis Range in 2014 by No Fuss and was a phenomenal success, with riders from 22 countries taking part.
The on-going success of WEMBO since 2014 has seen a huge growth in participant numbers and interest in 24-hour racing across the world.
WEMBO Australian founder Russ Baker said: 'World Solo 24-hour legend Jason English rated the 2014 'WEMBO' at Fort William the toughest course he had ridden. Italy's Gaia Ravaioli will defend her crown, while Jason attempts to regain his after coming second to Canada's Cory Wallace in 2017, which ended the longest run of world solo 24-hour championship wins in history.
'WEMBO has a bright future with events on the books up to 2022, with all events after Scotland being at new and exciting locations, starting with Brazil in 2019. I look forward to returning to beautiful Fort William and welcoming the world's riders to Nevis Range in October.'
Nevis Range is a world-renowned venue for mountain biking and the Fort William Mountain Bike World Cup has been massively successful and important to the area.
The fact that in 2018 alone it will see the Fort William Mountain Bike Downhill World Cup, an EWS Continental European Enduro and the World Solo 24 hours shows the diversity of riding available to all mountain bikers of all disciplines and experience.
Chris O'Brien from Nevis Range said: 'We are delighted to partner with No Fuss and host what we are sure will be two incredible events. We'll be working hard to make sure this happens and to demonstrate Nevis Range is much more than our world-famous downhill course and we can't wait to see that unique highland energy that always appears during a Fort William event.'
Frazer Coupland from No Fuss Events said: 'It is going to be an amazing couple of weeks. EWS are extremely popular with spectators, with Ireland and Italy having the reputation for the wildest crowds.
'The 2017 WEMBO was judged to have been one of the greatest parties ever witnessed at a 24-hour race. We see this as Scotland's big chance to get out and see some of the world's top enduro stars in action.
For information on the events and other events in the No Fuss 2018 programme go to www.nofussevents.co.uk/

subset: commoncrawl


text:
Become a White Ribbon Advocate
White Ribbon Advocates
White Ribbon Advocates are female representatives of White Ribbon who promote gender equality, respectful relationships and the engagement of men in order to see a nation in which every woman lives in safety, free from men's violence and abuse.
Who can become a White Ribbon Advocate?
The Advocate role is reserved for female White Ribbon Supporters above the age of 16 who wish to increase their engagement and participation with White Ribbon.
Supporters who wish to apply for the Advocate role need to meet the following criteria:
- Demonstrate an understanding of the link between gender inequality and men's violence against women
- Demonstrate an understanding and alignment with White Ribbon's unique role in engaging men to make women's safety a man's issue too.
- Demonstrate activity in the last 12 months which actively promoted gender equality, respectful relationships and the engagement of men to prevent men's violence against women.
White Ribbon recognises that men's violence against women pervades all cultures therefore we encourage diversity of age, sexuality, ethnicity, faith and ability among applicants to ensure change is effected across all levels of society.
How do I apply to become a White Ribbon Advocate?
In order to be eligible to apply, applicants must complete the following:
1. Register as a White Ribbon Supporter
2. Complete the "Understanding Men's Violence against Women" E-learning
Please save the e-learning Certificate of Completion as you will need to submit this as part of the application process.
When are applications open?
Applications to the White Ribbon Advocate Program are closed. The Advocate Program is open for applications annually from 1st – 30th April. Due to the recent intake in October 2017, the Advocate Program will not be open for applications until April 2019.
If you would like to register your interest for the Advocate Program, please complete the form below and you will be notified once applications are open.
What is involved in being a White Ribbon Advocate?
White Ribbon Advocates stand alongside White Ribbon Ambassadors at the forefront of White Ribbon as a community owned social movement. Advocates actively engage men in their spheres of influence to see the social change necessary to end men's violence against women.
The Advocate Program runs for two years and supports women across Australia with information, tools and development activities to promote gender equality, respectful relationships and the engagement of men in the prevention of violence against women.
White Ribbon Advocates are required to meet key milestone achievements under three streams over the course of their tenure; Educate, Engage and Act. These activities ensure that Advocates are adequately equipped with information and resources to effectively engage their local community to prevent men's violence against women.
If you have any queries related to the Advocate Program, please contact email@example.com


text:
|Pleasant Township v. Aetna Life Ins. Co., 138 U.S. 67 (1891)
Category: ALL
Sub-category: Case Law
In this nineteenth century case, the Court held that an Ohio statute authorizing certain townships to issue bonds for railroad construction violated the state constitution's prohibition on providing public aid to private corporations.
|Texas Building Authority v. jim Mattox, Attorney General of Texas, 686 S.W. 2d 924
Category: TX
Sub-category: Case Law


text: Peter is Chief Operating Officer for the Harry & Rose Samson Family JCC; providing executive leadership for membership, program and facility operations across 7 properties in Wisconsin (3000 membership units and staff of 300.) Peter has served as Director of Early Childhood Education at both the Merage JCC & Stroum JCC. A graduate of the University of Wisconsin-Madison, and past Fellow in Jewish Organizational Leadership, Peter's work in progressive Jewish ECE is well documented – as Faculty at Bellevue College, a board member for Children's museums, a keynote speaker and recipient of 2 Covenant Foundation grants.


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Doubling the Risk
A few weeks ago, the AAA Foundation for Traffic Safety released results from a two-year study that indicate drivers who skip even a few hours of sleep a night double their risk of being involved in a collision. And the more sleep people miss, the higher their risk.
The study focused on injury collisions between 6:00 a.m. and midnight. Researchers studied factors leading to the collisions, including errors committed by drivers, mechanical failures, and environmental conditions. The researchers asked drivers about how many hours they had slept in the 24 hours leading up to the collision, what their regular sleep patterns were, and whether the driver's sleep pattern had changed recently.
The results were clear: a driver's chance of being involved in a collision increases significantly when he or she is sleep deprived, and getting more sleep can help reduce our chances of being in a collision.
The AAA says that drivers with 5-6 hours of sleep a night had almost twice the crash risk of those with a full 7-8 hours. Those with only 4-5 hours of sleep had 4.3 times the risk, and those who got less than 4 hours of sleep during the last 24 hour period had 11.5 times the risk of being involved in a collision. Most alarming is that more than half of the drivers involved in these fatigue-related collisions had no warning before they fell asleep at the wheel.
I can't think of a better time than right before New Year's Eve to remind everyone that driving can be risky—and not getting enough rest or using alcohol and drugs while driving can be downright dangerous.
So PLEASE do not drive if you are intoxicated or if you haven't gotten enough rest; the risk just isn't worth it.
Almost every day, our local officers arrest someone for driving under the influence, and on New Year's Eve that number increases. During the holidays we want to celebrate with our friends and family, to remember the fantastic year we had and look forward to the promise of next year. But it is during these same holidays when we can let down our guard and drive while impaired, either while we're intoxicated or too tired.
This is when I worry most about our community and the dangers of driving. That's why, especially this time of year, our officers work as hard as possible to make our local roads as safe as they can.
Our officers have seen the results of driving under the influence (DUI) and they are passionate about removing intoxicated drivers from the road. Police officers don't want to be mean or unfair; in fact, it's just the opposite: they are committed to saving lives—lives we know can be taken when people drive while intoxicated.
Even if no one gets hurt or killed while a driver is impaired, DUI arrests and fines are expensive. A DUI can cost more than $2,700 in court fines and fees, plus additional attorney's fees, 48 hours in jail, the time to complete an alcohol education program, and loss of your driver's license.
So please, do the right thing this New Year's Eve and designate a sober driver to get everyone home safely. Decide at the beginning of the night who will drink and who will drive.
If you are with friends who have not planned well and it appears they should not be driving home, don't take "no" for an answer. I know this can be tough. It can be incredibly awkward to tell a friend or family member they shouldn't drive. But please take a stand: do not let anyone drive while intoxicated.
I can assure you our officers will take a stand. We will do everything we can to prevent drunk driving.
Please have a safe and very Happy New Year.
As always, our mission at UPD is simple: to make Ukiah as safe as possible. If you have suggestions on how we can improve please feel free to call me. If you would like to know more about crime in your neighborhood, you can sign up for telephone, cell phone and email notifications by clicking the Nixle button on our website: www.ukiahpolice.com.
Subscribe to Ukiah Police Department Hot Topics by Email


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BMW R1150R / Rockster Product Page
SITE NAVIGATION: Click the Product Name or Picture below to reach the item's web page. Once there, click on the Price to reach the Order Page or order directly by clicking on the PayPal button. For credit card orders, call us at 828.628.7093 EST. Please read DISCLAIMER before ordering. Note: All prices include USPS Priority shipping in the USA unless otherwise noted. and yes...We ship USPS Internationally! International customers will be notified of FedEx shipping costs after purchase or before upon e-mail request.
|Akrapovic R1150R Titanium Slip-On Exhaust System Perfected on the race tracks of Europe.. brought to you by Pirates' Lair. Witness the bad-ass looking S-B11SO2-HT Akrapovic Ti Slip-On Exhaust for the BMW R1150R. The Akrapovic slip-on exhaust offers all that you want or need in a slip-on kit. Great looks... Less weight.. More torque.. Deep sound.. Longer lasting erections. Change the nature of your bike by adding more power, improved performance, and the unique Akrapovič sound. Everything packed in stylishly designed Slip-On exhaust systems. According to Akrapovics website, this simple slip on kit is 27lbs lighter than oem, although I find that very hard to believe. The system fits beautifully with the strong character of the BMW. Sleek.. Dynamic. System retains centerstand capability. Fits
the 2001-2006 BMW R1150R & Rockster
Pirates' Price $697.US Slip-On (Ground shipping in US Included)
|Pyramid Plastics Extenda Fenda Pirates Lair gets more requests for fender extenders than any other single item other than naked pics of Amber. The Extenda Fenda is an inexpensive farkel that actually has a function. Designed to protect your bike from debris thrown up by the front tire The British made extenda fender helps keep rider and bike cleaner, cuts down on paint damage on the lower fairing, and also protects important parts of the bike such as the radiator and oil cooler. Chimp easy install. Fits every model year K1200RS, 2002-05 K1200GT, R1150R, and R1150RS.
Pirates' Price $47.US (Shipping in US Included)
Original Grip Buddies Made in the USA. Isn't it frustrating that virtually every new motorcycle comes with crappy hand grips? What up wit dat? Most are paper thin and contribute to discomfort within only a few miles.. Rather than contemplate expensive (and hard to install) replacements grips, consider Grip Buddies. These US made neoprene grip wraps are a wonderful grip option for those wanting more comfort, less vibration, durability, and a no-drama chimp-easy install. With Grip Buddies there is no need to remove your OEM grips.. Just wrap these babies around them (they attach via Velcro on the underside) and you're ready to ride in just a few minutes. Heated-grip compatible. A durable, long-lasting solution that won't migrate like some other brand grips. Instant comfort without breaking your wallet. Fits all BMWs
|Grip Buddies "Lite" Comfort Grips Made in the USA. Grip Buddies Smartskin Lite Comfort Grips are a wonderful grip option for ladies or men with smaller hands wanting more comfort, less vibration, durability, and a no-drama chimp-easy install. The texture and tactile feel is the same as the original Grip Buddies, just less bulky. We're told that heated grips warm up noticeably faster with the thinner Smartskin Lites compared to the original Grip Buddies. Smartskin Lite Comfort Grips are made from the same rubber-rich neoprene as the originals, they're just thinner: 3.2mm for Lite vs. 4.7mm for the original. With Grip Buddies there is no need to remove your OEM grips.. Just wrap these babies around them (they attach via Velcro on the underside) and you're ready to ride in just a few minutes. Heated-grip compatible. A durable, long-lasting solution that won't migrate like some other brand grips. Instant comfort without breaking your wallet. Fits all BMWs
Pirates' Price $26.95 Pair (USPS Shipping in the US included) New Product!
Aluminum Gas Cap A Pirates' Lair Exclusive! Imported
from Oberon Machine in the UK.
Up until now, you
could buy a billet gas cap for just about
any bike in the universe except for.. yep.. you guessed it... a BMW. No
idea why.. Are we not worthy? You've seen them on race bikes around the
world now you can have one for your BMW. This is a direct replacement
for your factory fuel filler cap and includes stainless steel fasteners.
In case you are wondering.. No.. they don't lock.. and neither do the
gas caps on any 4-wheeled vehicle you own so for gods sake.. unless you
live in an area with roving bands of petrol thieves willing to risk 2
years in jail for $9 worth of gas...Relax and fagetaboutit. These should
fit the K1200S, K1200R, K1200R Sport, K1200RS, early and late K1200GT,
and probably most BMW's.. Is this beeeautiful or what??
Pirates' Price $136.US Kit (USPS Priority Shipping Included)
|BMW R1150R Stealth Backrest A Pirates Lair Exclusive! Our black R1150R Stealth bracket bolts underneath your rear oem rack and allows for easy on/off backrest use. The stainless steel bracket (with stainless steel hardware) is almost completely invisible when on the bike. The backrest slides off in 15 seconds! No mods necessary. The fabric on our cover matches the oem seat perfectly and will look factory. Semi-soft luggage is available. Fits all model years BMW R1150R As this backrest has been discontinued we are always looking for used kits on the open market. When we find them we refurbish when necessary and sell here. Cash, MO, or check only.... Customer Comments Click Here Manufactured in the USA by Pirates' Lair.
Pirates' Price $410.US (Shipping in US Included) (1) Pre-Owned Kit In Stock for $350US. EMail Us If Interested..
Stealth Luggage by T-Bags Pirates Lair offers 2 choices of accessory
luggage for your new R1150R
Stealth Backrest. The
Roll Bag... and the Universal Helmet Bag.
Both slide down over the backrest via a tailored sleeve and then lock
securely into place with quick release clips. Both offer EASY access
and a rigid design so they maintain shape when empty thanks to dual
wall construction. Waterproof? Yes, when used with the custom tailored
rain sleeves that come standard with each bag.. FYI.. the Roll
bag is a great around town bag.... For two-up, I suggest the Universal.
|RKA "Sonoma Series" Soft Saddlebags Been looking for some soft saddlebags for your bike? Refuse to pay your dealer over $700+ for their optional oem bags and butt-ugly bracketry? I don't blame you. So what to do? We turned to our good friends at RKA Motorcycle Luggage for an alternative and of course they had 2 bags to fit our customer's needs.. 33 Liter Expandable Saddlebags and 50 Liter Expandable Saddlebags. Installation on virtually any motorcycle is "chimp"easy. Check out their install video. Saddlebags are sold as a SET. Both left and right bags. Raincovers are included. All Saddlebags are Black with Silver piping and have a limited-lifetime warranty. Possibly the nicest soft saddlebags you'll ever see. And yes.. RKA products are made here in the USA.
Pirates' Price 33Liter $280.US / 50 Liter $330.US (USPS Priority Shipping in the US included)
|ZTechnik Storage Pod Are you like me and would rather have a salt encrusted, flaming, pointy stick shoved in your eye than stick an ugly tankbag on your bike? If you aren't a back-pack kinda guy/gal, here's another way cool option from ZTechnik. Their roomy 4-liter Storage Pod™ offers a stylish and practical way to carry the essentials. Removable inner tray features three zippered storage pockets and a zippered document holder. Web straps and vinyl coated hooks allow universal mounting on almost any bike. While the mounting straps are about as generic as it gets and will fit most bikes, the Z Storage pod will probably NOT fit every motorcycle. I suggest you evaluate your bike and where the strap clips will mount before ordering. I'll be glad to furnish install tips and pictures for the BMW K1200S via email request. The Z Storage pod is made of a durable canvas over a thermo-molded pod. It holds it's shape whether empty or full. Dimensions are H: 4.5-6.0 in. W: 9.0-12.5 in. L: 13.75 in.
Pirates' Price $200.US (USPS Priority Shipping in the US included)
DrySpec D38 Rigid Motorcycle Dry Bag The DrySpec D38 Rigid Motorcycle Dry Bag is constructed of RF welded 22oz. vinyl that guarantees 100% waterproof performance even when submerged. The D38 features a rigid core that enables the bag to be mounted to any bike, with or without a top rack, even when the bag is completely empty. Try that with a traditional dry bag! The rigid construction and unique 4-point strap mounting system work together enabling easy access to contents without loosening straps or removing the bag from the bike. This is my personal favorite Drybag. Retro Reflective Logo / Adjustable & detachable carry handle / 38 Liters / 100% waterproof / 22" long x 12" wide x 9" tall / 22oz Vinyl & coated Cordura. Available in Black, Orange, or Gray.
|DrySpec D28 Dual-End Motorcycle Dry Bag The DrySpec D28 Dual-End Motorcycle Dry Bag is constructed of RF welded 22oz. vinyl that guarantees 100% waterproof performance even when submerged. Unlike other dry bags, the D28 features a dual-end roll design that allows access to belongings from either end of the bag without having to disconnect the mounting straps. The D28 is perfect by itself for short trips, but is the ideal add on bag for your existing side cases. Dual-Ended opening/ Universal quick release mounting straps (included) / Includes 4 straps / Retro Reflective Logo / Strap keepers to secure excess webbing / Welded carry handle / 28 Liters / 100% waterproof / 22" long x 9" wide x 9" tall / 22oz Vinyl & coated Cordura. Available in Black, Orange, or Gray.
Pirates' Price $102.US (USPS Priority Shipping in the US included)
|DrySpec B50 Wide-Mouth Motorcycle Dry Bag The DrySpec B50 Wide-Mouth Motorcycle Dry Bag is a universal roll-top dry bag made from rugged 22oz vinyl and coated Cordura and is guaranteed to be absolutely watertight. The B50 can be mounted parallel or perpendicular to almost any bike. Comes with a removable carrying handle for ease of portage. Unlike the other DrySpec bags, you'll have to furnish you own straps and/or bungee cords with this one. Whether your motorcycle decides to take a nap during your favorite water crossing or the skies let loose torrential rain, keep your essential gear stowed and dry with the DrySpec B50 Wide-Mouth Motorcycle Dry Bag. 12" wide x 12" tall x 22" long (average packed dimensions) with a 22" wide opening / 50 liter capacity. 4 D-rings on the bag accept a wide variety of strap options. Available in black only. *Straps not included.
Pirates' Price $125.US (USPS Priority Shipping in the US included)
|NSSC HID Motorcycle Lighting Kits The NSSC H7 HID conversion kits we have chosen for our menu are as plug & play as you're gonna find in an HID kit. No splicing, no wiring headaches, minor brain drain, no heat issues, and no smoking wallets. NSSC HID conversion kits use ultra slim digital ballasts designed to fit into the tightest spaces. Measurements for the ballast is 3.5" x 2.5" x 0.5" at only 8oz each. The ballasts are waterproof and are designed to withstand the shock and vibration of a motorcycle. These 35w NSSC HID bulbs produce a super bright 4000 lumens and at a color temperature of 5000K. Each bulb slots perfectly into the spot of the old bulb. CanBus compatible. Simply the brightest bulbs you can get. What are you waiting for? Isn't your life worth it?
Pirates' Price $68.US (Shipping in US Included)
|Jiayou H7 LED Headlight Bulbs The Jiayou New Energy H7 LED Headlight bulb is truly plug & play. No splicing, no wiring headaches, no brain drain, no heat issues, no depleted wallet. These should work on virtually any motorcycle or car that uses H7 bulbs. We sell single bulbs or pairs. The Jiayou LED headlight bulb is super small making it easy to fit into the tightest spaces. These kits are waterproof, shock-proof, last for a claimed 50,000 hours (compared to 850 hours of your oem bulb), and run cooler than either halogen or HID bulbs. Each bulb produces a serious 4000 lumens at a color temperature of 6500K. For reference, your oem halogen bulb puts out only 1000 lumens and is rated for no more than 850 hours. Each bulb plugs directly into the oem wiring harness. And yes.. they are CanBus compatible. 2 year warranty. I run these in my BMW K1200S. Witness the future of motorcycle lighting..
Pirates' Price $44.US (Shipping in US Included)
|Pirates' Price $140.US (Shipping in US Included)
|Pirates' Price $150.US (Shipping in US Included)
Blazer License
Plate Frame The 3 rows of high intensity
LED's used in the Lite-Blazer license plate frame will definitely get
the attention to vehicles several hundred feet behind you. The outside
LED's burn RED all the time as running lights,
like Lite Buddy's and the center LED's are a solid stop light (it is slightly brighter then
the running lights). When the brakes are applied, the built in flasher
causes the outer clusters to flash 6 - 7 times and remain on solid after
that, so you do not piss off the bubba/ex-SEAL/Postal employee sitting
behind you. Plate frame is black. Easy install. Make sure those french
fry eating, cell phone hugging, cage demons can see you when you are stopped.
Fits EVERY BMW. For
a Video MPG of the Lite Blazer in Action... Click HERE
Pirates' Price $100.US (USPS Priority Shipping Included)
|Lite Buddy's These super bright LED solid
state lights are just one solution to rear visibilty for your R1150R. Lite Buddy's fit inside the turn signal housings,
draw only a few milliamps, and show bright red
through the yellow turn signal lenses when your brakes are applied. Very
unobtrusive. Easy 2 wire install with no mods or drilling. Completely
out of sight. Increase your rear visibility by 100%. And for those who
want running lights AND flashing brake lights we also offer the optional
Stop Alert which when used with the Lite Buddy's will flash 6-7
times when your brakes are applied and then go back to running lights.
Pirates' Price $82.US (USPS Priority Shipping Included)
|Run-N'-Lites Turn
your R1150R turn signals into permanent running lights. The Type 10
Kit (shown here on a K1200RS) which fits both the FRONT and REAR of
the R1150RS, illuminates the stock turn signal housings with a low intensity
light making you more visible to cages... and safer. One hour easy installation
without cutting or splicing wires. Bulbs are standard automotive. Really
makes a visual difference... day and night!
Pirates' Price $39.US per kit (USPS Priority Shipping Included)
|Denali SoundBomb Compact Air Horn Imported from Italy. Are you sick and tired
of some cage trying to take your lane while you happen to be using it?
Don't get mad... get LOUD. The Denali black dual-tone air horn is rated at 120 freakin' dB at 3 feet so you'll be
as loud as most European cars. Includes a relay for providing a direct, high current attachment
to the motorcycle's battery. The Denali SoundBomb is 800%
louder than your single factory meep meep horn. Feel safer.. Stay alive...!
Fits virtually all motorcycles if you have the room. Remember, these
are larger than your stock horn so you'll need space and clearance for
a single 5.3" x 4" x 3.3" air horn. Plug-N-Play wiring kit available. Honestly, install
on any bike using our plug-n-play harness is chimp easy requiring only a little imagination for horn placement. I have one of these on both my bikes. Simply the best aftermarket horn on the market.
Pirates' Price $65.US (Shipping in US Included)
|PDM60 Power Distribution Module Are you turning your ride into a Frankenbike with splices and wiring and electrical tape stretched all over creation? Move into the 21st century with the PDM60 Power Distribution Module. With the PDM60, there's no more blown fuses, tangled wiring, overloaded circuits, CanBus related power interruptions, confusion, or frustration. The PDM60 is fully user programmable via the PDM60 dashboard software. You can set circuit triggering/switching methods, delay circuit activation/deactivation, and individual circuit amperage levels. With the PDM60 you get six power circuits and 60 Amps of power handling capability. That's enough to handle all of your accessories.. radar detector, lights, horns, heated gear or grips, GPS, cell phone, etc, etc... CanBus compatible.. Easy 3 wire install.
Pirates' Price $220.US. (USPS Priority Shipping in the US included)
|Stop & Go Mini-Air Compressor If you do enough riding.. sooner or later you're gonna have a flat or need some air. It's not a matter of if, but when. The Stop & Go Portable Mini-Air Compressor measures only 4 x 2 x 6" making it possible to be carried on virtually any motorcycle, scooter or ATV. The built in gauge allows you to observe the increased pressure with a reading up to 120 psi. It also comes with a built in LED light letting you know that it is receiving power and helps you connect to the tire valve after dark. Your motorcycle tire will be fully inflated in less than 10 minutes. On the road or in the wilderness you will always have clean outside air available and there's never a need for replacement parts or re-fills. Do you want to be prepared the next time you or your buddy gets a flat? Of course you do.
Pirates' Price $55.US. (USPS Priority Shipping in the US included)
|Stop & Go Pocket Tire Plugger Kit If you do enough riding.. sooner or later you're gonna have a flat. It's not a matter of if, but when. The Pocket Tire Plugger Kit from Stop & Go gives you the ability to perform the most effective repair possible without dismounting your tubeless tire. With this kit, you'll be back in action in just a few minutes. With the addition of (4) 16 gram canisters of 100% pure high velocity CO2 gas and the 4" fully flexible adapter with solid brass fittings, this kit includes everything needed to repair and re-inflate your tire. The mushroom-type plugs expand under pressure working much better than those crappy sticky strips that cheaper kits use. The kit measures 5" x & 7 1/2" x 1" and weighs only 18 ounces. My kit fits easily under the seat of my K1200S. This ain't the cheapest kit on the market, my friends.. but IMHO.. it's the best. Do you want to be prepared the next time you or your buddy gets a flat? Of course you do. The question is.. Do you feel lucky? Well.. do ya punk?
Pirates' Price $55.US. (USPS Priority Shipping in the US included)
|Signal Dynamics LED License Plate Frame Check out the waaay
cool Signal Dynamics LED License Plate Frame. Achieve a classic look with this sleek black license plate frame. It has 18 Ultra Bright Red LEDs! The LEDs function at high and low intensity to function as auxiliary brake and running lights! The Signal Dynamics LED License Plate Frame draws
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Designed to accept the most commonly used 7-1/2" license plates used in the USA. Luddite approved. This is what I have on my own K1200S. Fits virtually every motorcycle.
Pirates' Price $78.US (Shipping in US Included)
Parnes R50/RS/GT Wheel Balance Kit Some us us choose to
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|Raci-Baby WickIt! Helmet Liner The WickIt! helmet liner is constructed of comfortable stretch fit active wear. The premium quality, silky-soft, stretchy active wear material is thin and lightweight and provides a comfortable fit under all types of helmets. The WickIt!'s unique material helps keep you cooler in hot weather by wicking away moisture and enhancing the evaporative cooling effect. In the winter the wicking process keeps humidity away from your skin providing a comfortable feel when worn under insulating hoods and other cold weather gear. One thing I like about the Raci-Baby is the design at the rear. The triangle tail makes it easy to orient the helmet liner! - No more fumbling trying to figure out what's front and back. Easy on.. easy off. The Raci-Baby WickIt! One size fits both men, women, and/or those unsure of their sexuality. I've been wearing one of these for a few years now and I deem it worthy of our elite clientele.. And did I mention these are made right here in the USA??!!
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Happy Sunday, my brilliant B-Loungers! I've been busy as f*** teaching children, buying a house, and entering a new decade. It's been quite the month, so let me fill you in.
First off, I got my kickass sleeve outline! A Japanese traditional Alice in Wonderland mash-up, one of my many original and awesome ideas. Check it:
You know you've got a good tattoo when a worker at the shop says, "I don't get jealous of tattoos… but I'm jealous of this one." My artist truly brought my vision to life. My first color session is in January, so I'll be sure to update you.
My latest culinary venture was paella, a magical dish that seemed easy enough. Well, I royally f***ed it up and ended up with a terrible, blackened mess.
It started out strong: The turmeric was smelling great, I had some garlic, onions, and peppers nicely cooked, and Husband even exclaimed how great things smelled. Look how great it looked!
Then I got to the point in the directions that says to put two cups of uncooked rice in the pot and let it simmer. Now, I've never cooked rice outside of a rice cooker, so I was already a bit apprehensive, but I figured as long as I follow the directions, I can't go wrong.
Big. F***ing. Mistake.
I'm simmering away, like the recipe instructed, when I start to smell something burning. Figuring that might happen, I stir the pot and attempt to scrape some of the burnt rice off the bottom. I stir a little more and let it simmer. Smoke starts slowly rising from the pot, then quickly crescendos into a billow. I heave the massive pot of mostly goodness off the heat and frantically stir. I'm only 6 minutes in to the 10 minutes of simmering, and that rice is still hard as pebbles. What the hell do I do?!
"Well, better just see this shit through," I thought. I put the pot back on the heat and just let that motherf***er ride.
Needless to say, we had to open all the windows.
Honestly, the flavors were on point save for the burnt taste that permeated through the entire dish. Damn it all to hell! It even looked good, save all the black burnt bits:
Well kids, the takeaway I got from this experience was to cook the rice in my rice cooker beforehand and add it at the end. I'm simply too noob a cook to get this dish right by conventional means. I spent 35 minutes yesterday scrubbing the shit out of my pot, and I still don't have all the black bits out. At least I got a good arm workout!
So my husband and I are hitting a milestone and buying our first house, and Jesus Christmas cards talk about a lot of paperwork! I'm so thankful for 21st century E-Signing… I can't even imagine what that was like before my beloved technology! Signing all that shit by HAND?! And NOT in my underwear on my couch?! F*********ck that! Just because it's computer friendly doesn't mean it doesn't have its problems, however, as we learned one long, frustrating night.
The day we were to get our contract, our agent texted me at 5:48PM to let us know she sent it to us. So I immediately go to my email and scour my inbox and junk, yielding no results. I double-check to see if she sent it to the address I gave her. She didn't — apparently she somehow had an outdated Gmail account that I never use. I text her my current Outlook email address, and she says she'll resend.
6:06: Realtor asks if Husband received his email. He had; I still hadn't. Says she'll resend.
6:42: Still nothing. She says she'll delegate on my husband's contract so he can sign for me.
7:08: No delegation email for the initial documents. I create a new Gmail account, since Outlook sucks, and send her updated email address.
8:03: Realtor advises to check email now. Had to redo the papers so both our names are on them. Husband receives new paperwork, but I still haven't received anything. Realtor says she's delegated him so he can sign for me. Doesn't work.
8:26: Realtor advises she's going to double-check my email address.
9:39: Receive the HOA docs, but still no contract docs. We decide to call her to spell out my email address, because she has to be typing it in incorrectly. Find out that she was spelling my last name F-i-o-r-E, not F-i-o-r-I. Husband and I decide my new email address should be email@example.com. Unfortunately, Google frowns upon profanity and refuses to create the address.
10:20: Finally, five hours later, we get the mother***ing documents signed, or rather, Husband electronically signs them for me, as I have passed the f*** out and won't wake up.
The kicker? She gives my email incorrectly (same mistake) to the title company the following day. *bangs head against wall* Thankfully, her realtor skills are vastly superior to her spelling.
Have you ever made paella? What do you think of my new ink? Any funny realtor stories? Leave me a Reply and let me know! I'd love to hear from you.
Till next time, my digital friends. Stay hydrated!


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Minute prizes:
End of the Year:
Students will be eligible for an end of the year prizes based upon their progress in Moby Max, minutes, ranking amongst their peer in their grade level and overall ranking amongst all three grade levels. The end-of-the-year prizes are meant to be a motivational, productive way to enhance student's knowledge of the core subject, mainly math and English language arts.
Each student is eligible to receive a prize depending upon the amount of minutes that they work on their lessons with Moby Max. Students who chose to work on Moby Max for at least 45 minutes per week will be eligible for a prize. The prizes are given to 1 student per grade level for each A day and B day.


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Comorbidity of Depression and Pain: a review of shared contributing mechanisms
Ai-Ling Li1,2,3*, Yuan Bo Peng1
Pain and depression are two major health issues that we are currently facing. Chronic pain is the main reason that people seek medical care; and numerous people commit suicide each year because of depression. These two pathological conditions often coexist. Chronic pain patients are more likely to develop major depressive symptoms, while depressed patients reported more pain symptoms than normal healthy population. Understanding the common mechanisms associated with depression and pain is important for developing the effective strategy to treat this comorbidity. In this review, the potential mechanisms that contribute to both depression and pain are discussed from four perspectives, the morphological changes in the brain, monoamine deficiency, brain-derived neurotrophic factor (BDNF) reduction in the hippocampus, and the hypothalamic-pituitary-adrenocortical (HPA) axis dysfunction.
Both chronic pain and major depression (MD) are important health issues. Pain is the leading reason that patients seek medical care. The annual cost pf pain (combining the health care cost and loss of productivity) in United States ranges from $560 to 635 billion, which is greater than the annual costs of heart disease, cancer, and diabetes1,2. Depression now is the leading cause of disability worldwide and is estimated to affect 350 million people3. These two conditions often coexist. The prevalence of pain in patients with MD and the prevalence of depression in chronic pain patients are higher than the prevalence of pain or depression in general population4. Moreover, the condition of one can exacerbate the other. Chronic pain patients with depression are more likely to have higher severity and longer duration of pain, and the presence of pain is associated with increased depressive symptoms and possible relapses4–7. The detailed epidemiological information about the comorbidity of pain and depression was reviewed by Bair et al., (2003). It is important to treat pain and depression concurrently in comorbid populations. By targeting the common mechanisms shared by both pain and depression, we can better treat these comorbid conditions. This review discusses the potential mechanisms that contribute to both depression and pain from four perspectives, the morphological changes in the brain, monoamine, brain-derived neurotrophic factor (BDNF), and the hypothalamic-pituitary-adrenocortical (HPA) axis dysfunction. The animal models for pain and depression are also briefly reviewed.
Brain imaging studies and post-mortem studies showed that patients with depression had abnormal morphology in many brain structures8. Grey matter reduction is one of the major reasons. Left anterior cingulate cortex (ACC), which is ventral to the corpus collosum and is also called subgenual prefrontal cortex (SGPFC), showed prominent grey matter reduction in depressed patients9. Reduction of this area was found both in young women with early onset MD and middle aged women with recurrent MD10. The reduction in left posterior SGPFC is more prominent in MD patients compared with patients with other psychotic disorders, such as schizophrenia11. Decreased blood flow and activity in this area may contribute to the decrease in volume12. Hippocampus also exhibited volume reduction in depressed patients13,14. Reduction in hippocampus was seen in patients with a history of early-life adversity15,16 and subjects with multiple depressive episodes17. Basal ganglia is another brain area showed grey matter reduction in depressed patients, more specifically the reduction was seen in putamen18,19 and caudate nuclei20,21. Besides grey matter reductions, white matter abnormalities have been observed in depressed patients22,23.
Chronic pain patients showed grey matter reduction in many brain areas. The most common areas that have grey matter decrease in chronic pain patients are the frontal cortex, ACC, insula, some areas in the temporal lobe24–30. Other areas, such as the thalamus, amygdala, motor cortex, and cerebellum, etc., also showed a decrease of grey matter depending on the type of chronic pain and disability the patients have31–33. The decreased grey matter was reversible in some cases after the pain was gone or was successfully treated28,30,34. Areas with increased grey matter were also noticed in some studies, such as the increased grey matter in the somatosensory cortex of migraine patients35, which is probably related to its crucial role of processing noxious and innocuous sensory information.
Structural changes of brain areas involved in both depression and pain appears to be consequences of these pathological conditions instead of causes, because these changes were reversible once the depression36 or chronic pain28,30,34 has been treated. Overall, the brain areas that are mostly affected by both depression and pain are ACC, and the hippocampus in the temporal lobe. ACC is directly or indirectly connected to many other brain areas37, and is involved in the integration of emotion, cognition, autonomic function and conflict resolution38; these functions are disturbed during depression39. Additionally, ACC is highly involved in the affective component of pain40. The hippocampus in the temporal lobe is important in learning and memory, which are impaired in both depressed patients41 and some chronic pain patients42. Therefore, abnormality of ACC and hippocampus can contribute to the symptomology of both pain and depression.
There are two major classes of antidepressants: the tricyclic antidepressants which block the plasma membrane transporter for serotonin (5-HT) and/or noradrenaline, and monoamine oxidase inhibitors which reduce the enzymatic breakdown of 5-HT and noradrenaline. Both categories increase the level of monoamine, which leads to the hypothesis that depression is caused by a deficiency of monoamines, such as noradrenaline, 5-HT, or both36,43. Therefore, based on this hypothesis, monoamine depletion was utilized to study the direct effects of monoamine on mood. However, conflicting results were found in heterogeneous populations. The monoamine depletions only had an effect in subjects with a family history of major depressive disorder (MDD) or in drug-free patients with MDD in remission, but did not decrease mood in healthy humans44. Additionally, it requires weeks of treatment with antidepressants to produce mood changes in clinical population, despite the relatively immediate increase of monoamine transmission after the administration of these drugs. Therefore, it was hypothesized that acute increase of monoamine induced by antidepressants produces secondary neuroplastic changes which takes longer time and alleviate depression43. In line with this hypothesis, studies have found antidepressants increased calpactin I light chain/annexin II (p11) which could increase serotonin 1B receptor (5-HT1B) receptors at the cell surface45 and upregulate the transcription factor cAMP response element-binding protein (CREB)46.
Monoamines play an important role in pain, especially in the descending inhibition of pain. The spinal cord is innervated by noradrenergic nuclei located in the brain stem47. The noradrenergic projections to the dorsal horn modulate nociceptive signals before their transmissions to higher centers. Both stimulation of locus coeruleus48 and direct administration of noradrenaline to the spinal cord49,50 were antinociceptive. The release of noradrenaline acts predominantly on α2-adrenoceptor subclass and can inhibit transmitter release from primary afferent terminal and therefore suppress the activation of projection neurons in dorsal horn47. Serotonergic projections to the spinal cord mostly derives from rostral ventromedial medulla (RVM) and the dorsal raphe nucleus47. Both acute and chronic exposure to noxious stimuli can activate serotonergic neurons in the rostral ventromedial medulla (RVM) and facilitate the turnover of 5-HT in the spinal cord, therefore inhibit nociceptive transmission at the spinal cord51. 5-HT3 receptors has been discovered to mediate the inhibitory effect of 5-HT on dorsal horn neurons upon periaqueductal grey (PAG) stimulation52.
Overall, monoamines are highly implicated in both pain and depression. The brain stem nuclei send descending projections to spinal cord to modulate pain transmission and ascending projections to different brain areas to modulate mood, cognition and physiological function. The disruption of serotonergic and noradrenergic systems can contribute to the comorbidity of pain and depression.
BDNF is the most prevalent growth factor in the central nervous system. It is known to be involved in survival and synaptic plasticity of central and peripheral nervous system. In human, the BDNF was significantly lower in depressed patients without antidepressant than those who were treated or control group53; and the BDNF was increased by antidepressant therapies54 and electroconvulsive therapy55. Similar phenomena were seen in animals46,56. Furthermore, direct administration of BDNF in the hippocampus can produce an antidepressant-like effect in animals. A single bilateral infusion of BDNF into the dentate gyrus of the hippocampus produced an antidepressant effect which lasted for at least 10 days in both learned helplessness and forced swim test (FST) paradigms57. This antidepressive effect of BDNF was comparable in magnitude with repeated systemic administration of chemical antidepressant57. BDNF was able to promote the function and growth of 5-HT containing neurons and increase the turnover of 5-HT and levels of noradrenaline in many forebrain areas58. Given the important role of 5-HT and noradrenaline in treating depression, the effect of BDNF on serotonergic neuron and serotonin suggested a potential link between BDNF and depression.
Similar to depression, reduction of BDNF in the hippocampus was observed during pain59,60. But BDNF increased in spinal cord dorsal horn60,61 and periphery62,63 under pain conditions. Spinal administration of BDNF resulted in decreased nociceptive threshold64 and allodynia61. The binding of BDNF to tropomyosin receptor kinase B (TrkB) receptor is possibly involved in the pronocicptive effect of BDNF, because the sequestration of BDNF by TrkB receptor chimera protein suppressed nerve injury-induced thermal hyperalgesia and tactile allodynia61,65. In addition, BDNF induced phosphorylation of N-Methyl-D aspartic acid (NMDA) receptors on the spinal cord neurons, which is necessary for maintaining pain hypersensitivity after nerve injury66.
Although the BDNF changes differently at different location under pain condition, both pain and depression had reduction of BDNF in the hippocampus. It is interesting that the induction of BDNF by intracerebroventricular injection of 4-methycatechol (4-MC) reduced both the pain and depression response in rats caused by chronic constriction injury (CCI) of sciatic nerve, and this effect was blocked by anti-BDNF antibody67.
This implies that the enhancement of BDNF in the brain may be a new treatment strategy for chronic pain associated with depression.
The HPA axis is involved in the "flight or fight" response to stress. It consists of hypothalamus, pituitary and adrenal gland. External stressor activates hypothalamus to release corticotropin-releasing factor (CRF) which is delivered to and stimulate pituitary gland to release adrenocorticotropin hormone (ACTH). ACTH reaches adrenal gland through circulation and activate it to release glucocorticoids, such as cortisol which is involved in glucose metabolism68. Glucocorticoid, in turn, can suppress the production of CRH and ACTH to serve as the negative feedback mechanism for the HPA axis. Activation of the HPA axis is an adaptive process and enables organisms to respond to various challenges. However, continued and prolonged stress may disturb the HPA axis to such an extent that the negative feedback mechanism is disrupted; and the adaptive response of HPA axis then becomes maladaptive69.
Dexamethasone (DST) has been used to detect the HPA abnormalities in melancholic patients70–72. DST is an exogenous steroid that can suppress the ACTH release by binding to the glucocorticoid receptors (GR) in the anterior pituitary gland. Depressed patients did not show such inhibition of HPA axis by DST, and some patients showed hypersecretion of cortisol at baseline70,72. Interestingly, not everyone who undergoes trauma develops abnormal HPA activity, only those who actually develop depression73.
This loss of inhibition of HPA axis or maladaptive of HPA negative feedback mechanism has been attributed to the glucocorticoid receptors (GRs) which play an important role in the negative feedback regulation of the HPA axis. Patients with bipolar or major depressive disorders, as well as first-degree relatives of those patients, displayed GRα mRNA reduction74, which indicates the genetic involvement. Genetic manipulation of GR expression in mice made animals more prone to develop depression-like behavior by under-expressing GR or more resistant to depression by over-expressing GR75. Antidepressants can also modify GR mRNA concentrations in primary culture of rat hypothalamic or cortical neurons76, elevate GR concentration in hypothalamus77, and reduce basal, as well as stress-induced plasma ACTH and corticosterone77. Therefore, antidepressant may alleviate depression through increasing the number of the corticosteroid receptors and restore susceptibility of HPA axis to negative feedback by cortisol78. It is true that drugs specifically targeting HPA axis have shown promise in ameliorating depression symptoms69.
Unlike the depression for which the hypercortisolism is a common phenomenon, hypocortisolism is more common in chronic pain patients79–81. No escape from DST was observed in fibromyalgia (FMS) patients81. However, not all pain patients are associated with low cortisol level. Women with shoulder and neck pain had a tendency to develop higher elevated cortisol levels, and this hypercortisolism was suggested to represent an intermediate stage towards the development of a hypocortisolism in wide spread musculoskeletal pain80.
In summary, both pain patients and depressed patients showed maladaptive HPA function. However, depressed pain patients are more likely to develop hyperacitivity of HPA axis and result in hypercortisolism, while pain patients develop hypocortisolism.
Animal models are great surrogates to study human disease in basic and preclinical research. They are pivotal for understanding the underlying pathophysiological mechanisms of disease and development of effective therapy. Therefore, the animal models of depression and pain are briefly summarized in this section to better understand how the animal models can be used to study the comorbidity of depression and pain (for more comprehensive and thorough reviews of depression models see82–84, and pain models see85–87).
Some depression models are used to screen for the efficacy of antidepressants. These tests are easy, low-cost, and highly reproducible; such as FST and tail suspension test (TST), in which animal is forced to swim in a confined space or is suspended by its tail respectively82–84. In these tests, animal becomes immobile after the initial struggle. The total immobility time is sensitive to anti-depressive treatment. Some other depression models incorporate stress as the major determinant. Learned helplessness introduces the uncontrollable and unpredictable stress, and results in the loss of motivation to escape in animals82–84,88. For example, a rat is placed in a chamber divided into two halves, with one of them is equipped with the floor which can deliver electric shock. Animal learns to escape to the safe side when hears a warning tone preceding the shock. However, if the animal is confined to the side with shock and receives several unavoidable and uncontrolled shocks, animal will subsequently fail to escape when he is allowed to84. In the chronic mild stress (CMS) model, animals are exposed to a series of mild and unpredictable stressors for at least 2 weeks, such as isolation or crowded housing, food or water deprivation, disruption of dark-light cycle, tilted home cages, dampened bedding, etc82–84. And sucrose intake is used as readout of anhedonia in this model. Additionally, social stress is adopted in depression models by introducing an intruder to the stable social group or mixing different social groups; and maternal separation is used as an early life stressor. Furthermore, there are depression models based on the putative pathophysiological mechanism, such as the deficiency of monoamine. Reserpine, a vesicular monoamine transporter blocker, has been used to deplete synaptic monoamines in depression models82–84. Others employ genetic manipulation to create mutant lines that display depressive symptoms82,83.
Animal pain models have been created in an attempt to recapitulate clinical conditions. To create inflammatory pain, irritant inflammatory agents are injected into different parts of the body, such as cutaneous and subcutaneous tissue, joint, and muscle, etc89. For example, formalin can be injected subcutaneously in the hind paw of rodents to induce biphasic pain responses. The initial phase lasts about 5 min after the injection, and then after quiescent period, a second phase persists for about 45 min. The spontaneous pain behaviors, such as flinching, shaking, or jerking of the injected paw, are quantified to indicate the present pain induced by formalin85,89. Other commonly used irritant algogenic agents are capsaicin, Freund's adjuvant, and carrageenan, etc. When these agents are injected intraperitoneally or directly into the hollow organs, such as colon, visceral pain is produced and writhing response can be measured85. Another major type of pain is the neuropathic pain which results from the injury or dysfunction of the nervous system. Many surgical variations have been invented to injure the nerve. For example, there are complete transection of the sciatic nerve, tight ligation of dorsal one third to half of the common sciatic nerve, tight ligation of L5 spinal nerve, tight ligation of peroneal and tibial nerve while leaving sural nerve intact, or spinal cord contusion, etc86,87. Inflammatory agent, such as zymosan, can also be applied to the nerve to induce neuropathic pain86. Additionally, chemotherapy-induced neuropathic pain is commonly seen in patients who receive chemotherapeutic drugs. Therefore, chemotherapeutic agents, such as vincristine, cisplatin and paclitaxel, have been repeatedly injected to animals to produce chemotherapy-induced peripheral neuropathy. Other disease-induced neuropathy models are diabetes- and cancer-induced neuropathy86. Many of the pain models can result in the peripheral hypersensitivity which can be measured by the reduced threshold to thermal or mechanical stimuli. To measure the hypersensitivity to mechanical stimuli, a pressure of increasing intensity is applied to the hind paw until the paw withdrawal. For example, a series of von Frey filaments of different diameters (producing different pressure when bent) are applied to the ventral or dorsal surface of the hind paw. The lowest pressure that produces withdrawal response is regarded as the mechanical threshold. Similarly, the thermal hypersensitivity can be measured by the reaction time of certain behavior when exposed to a thermal stimulus. An example of such test is the Hargreaves test in which a radiant heat is directed toward the plantar surface of the hind paw and the latency of paw withdrawal is recorded as the thermal threshold90. Sometimes, animal's response to cold is also measured. Vocalization is another parameter that is measured as the reaction to painful stimuli, and the stimulus intensity necessary to elicit a vocal response is determined85,89.
To study the comorbidity of depression and pain in animal models, it is necessary to evaluate the pain hypersensitivity in depression models and depressive proneness in pain models, and find the optimal model for the comorbidity of depression and pain. It can imagine that not every model will produce the same degree of comorbidity based on the differences in the etiologies and pathophysiological mechanisms for each model. Because the comorbidity was mostly seen in patients with chronic pain, it is more appropriate to incorporate chronic pain such as neuropathic pain, as opposed to the relatively transient pain such as formalin injection-induced pain. Furthermore, depression models with higher face validity involving stress as major determinant can better mimic clinical conditions as compared to the FST or TST.
As discussed above, there are common factors involved in both depression and pain: the grey matter decrease in ACC and hippocampus, deficiency in monoamine and reduction of BDNF in hippocampus. Although both depression and pain are associated with the malfunction of HPA axis, they differ in the direction of changes in HPA axis activity. Targeting at these shared mechanisms for pain and depression may increase the efficiency of treating patients with comorbidity of pain and depression. More research needs to be done in a comorbidity model to study the efficacy of targeting these factors in treating pain and depression. For example, does the increase of monoamine or BDNF level ameliorate both pain and depression? There is one study which has shown increased BDNF can increase pain threshold and alleviate depression in CCI model67, but more research needs to be done. Studies have shown that increased glucocorticoids and ACTH was able to increase monoamine oxidase activity to reduce monoamine level91,92. Decreased BDNF level could lead to changes of neuroplasticity and volume in critical brain areas46, such as the prefrontal cortex, ACC and hippocampus, which can result in the dis-regulation of mood and changed pain perception. Therefore, we also want to know how these mechanisms interact with each other and how they play as a whole in the comorbidity of depression and pain.


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Dubai: An Affordable Stopover with the "My Emirates Pass"
Planning a stopover or holiday to Dubai this summer? If so, there might be a way to save some money and enjoy a luxury vacation for less.
Dubai has a reputation of being one of the world's best hotspots for holidaymakers, as it offers an affordable escape while ticking all the boxes of what travelers normally expect: a relaxed outing at a beach, soaking up the sun and swimming in the tranquil water or fun-filled activities or many scenic landmarks, various attractions and adventure destinations.
This year if you are travelling with Emirates between 1 June and 31 August 2017 you might enjoy not only a great vacation but also great discounts. The "My Emirates Pass" Program is exclusively offered to international passengers holding an original boarding pass or e-boarding pass to Dubai that's issued by the airline; it offers commuters an affordable stopover to remember with the discounts, services or benefits being offered, including but not limited to:
- Dining experiences
- Leisure
- Mind & Body
This makes it even more a reason to do a Dubai stopover to explore Emirates' vibrant hub city.
Interested in Booking a Dubai Stopover? With My Emirates Pass, the Emirates boarding pass is now a gateway to a world of discounts and experiences all around the city. So get ready to visit Dubai for less this Summer.
So what can you see while in Dubai? Fore a relaxing vacation, you can stroll by the magnificent Persian Gulf shoreline featuring various developments (such as Jumeirah Beach and the Palm Islands, The World or World Islands in addition to the new built of Marsa Al Arab) and enjoy mouth-watering international cooking as well as many interesting and exotic dishes.
If you are looking for site-seeing adventures, you can drop in on the larger-than-life attractions (the Dubai Fountain Show or the Dubai Miracle Garden), go to see famous buildings (the edifice of Infinity Tower, Burj Khalifa and the Burj Al Arab), or take tour of a mosque highlighting Islamic architecture (Grand Mosque or else the Jumeirah Mosque) and, of course, book one of the many desert safari options. Let's not forget the experience to hop aboard of a 'dhow' Arabian wooden boat cruise on Dubai Marina. You can visit Dubai Aquarium, the Underwater Zoo or Ski Dubai.
If you'd rather indulge, then you can enjoy many luxury hotels (Jumeirah Beach Hotel or Atlantis the Palm Hotel & Resort) while planning your shopping at the souks or malls around the city (the Gold Souk, Dubai Mall or Dubai Outlet Mall, or else Mall of the Emirates).
When to go? To take advantage of the Emirates' discounts, make sure to fly to Dubai between 1 June and 31 August 2017 and save your boarding pass. However tourism in the Emirate is high year-round. The best time to visit Dubai is from November to March—the peak tourist season—where vacationers take advantage of the mild weather to go to the beach, enjoy a range of water sports, if not to relax in the sun while escaping cold at home.
Get your luggage ready!


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President Barack Obama spoke to an audience this week in Cleveland, Ohio, about his plan to stimulate the economy by helping out the middle class and small businesses.
Obama's talk comes on the wake of another speech in Cleveland made by Republican House Minority Leader John Boehner. He spoke about his party's solutions to the economic crisis, which included extending the Bush-era tax cuts to the wealthy.
Regarding the Republican plan, Obama said, "Instead of setting our sights higher, they're asking us to settle for a status quo of stagnant growth and eroding competitiveness and a shrinking middle class."
Instead, Obama would like to extend the cuts for only the middle and lower class, as well as expand the Research and Experimentation Tax Credit. He would also like to pass a small-business jobs bill, which would eliminate capital gains taxes on investments in small firms and give them more access to credit so they can invest and grow.
Obama said a true recovery "means making the long-term investments in this country's future that individuals and corporations can't make on their own: investments in education and clean energy, in basic research and technology and infrastructure."
"That means making sure corporations live up to their responsibilities to treat consumers fairly and play by the same rules as everyone else," he added. "Their responsibility is to look out for their workers, as well as their shareholders, and create jobs here at home."


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In 1996 two friends, Mike McElwain and Jerome Ebel bought an old brick building on Highway 10 in Junction City, Wisconsin. The building, built around 1920, was originally a Model A Ford dealership. Subsequently it had a barbershop, followed by a liquidator of second-hand goods, before being vacated in 1988. Purchased in 1996, it took two years to restore and clean the building before the first beer production could begin. With a building, the friends put together money to purchase used dairy equipment. The dairy equipment was retrofitted to ultimately become the brewery's first brewhouse. Months later, Central Waters Brewery came to be.
They began using their own home brewing recipes. The original included: Ouisconsing Red, Happy Heron Pale Ale, and Mudpuppy Porter. The pair also made an award winning barley wine. In 2000 their Kosmyk Charlie's Y2K Catastrophe Ale captured a bronze medal at that years World Beer Cup Competition. The initial brews were offered in growlers, twelve, and twenty four ounce bottles, and kegs.
Within a few months of first beer production, Paul Graham was hired to help so Jerome and Mike could maintain their full time jobs. The partner's start up was part of a national trend toward producing bigger and better beers at a small, local level. The exact opposite of what most Americans had seen since the emergence of modern refrigeration and big national brands, these microbreweries revisited pre-prohibition recipes and expanded them to include most varieties brewed across the world.
After three years under the original ownership, the brewery went up for sale. Brewer Paul Graham teamed up with, avid home-brewer and literal 'beer fanatic', Clint Schultz to purchase the building, equipment, and recipes. The team's choice only secured the place of craft brewing in Central Wisconsin. While the original beer lineup was good, Clint and Paul had ideas of their own. They expanded on the original three beers to five by turning seasonal favorites Lac Du Bay India Pale Ale (IPA) and Satin Solstice Imperial Stout into regular brews. In addition they also wanted to offer bottles in six packs. In order to achieve this the duo acquired an automated bottling machine.
Shortly after the acquisition of the bottling machine, the original brew house fired for the last time. Not being originally designed for the stress it was enduring, the main brew kettle cracked beyond repair. On the five-year anniversary Central Waters purchased a 15-barrel brew house, similar to the one here at the pub, and two 30 barrel fermenters to support the larger batches produced by the new brew house.
In early 2006, Clint Schultz left the brewery to pursue other interests. The brewery is now owned and operated by Paul Graham, Anello Mollica, and Craig Ziolkowski, who bring over 24 years of brewing experience into the company.
Currently, Central Waters Brewing Company has expanded its product line to include twelve beer styles and services over 50 retail locations in Central Wisconsin. Although, only two of the original dairy tanks are in use today, CWBC continues to build on the solid reputation of producing the finest quality beers in Central Wisconsin.
Here's a toast to Central Waters Brewery's raison d'etre "Making the world a better place, one beer at a time."
Click here for more information about Central Waters BrewPub
Feel free to contact us with questions and/or comments.


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About ANNA
ERA – Professor C.D.Rajeswaran Back
to Article Titles
years ago just when I joined the staff of Pachaiyappa's
College, I happened to be one of the judges in a competetion.
A smartly dressed and in the werstern style too, there appeared
an young man who so impressed all the judges that he knocked
away the prize. And the next day I found him in my class which
I was taking in politics for the B.A. Honours students. That
is young Annadurai and I was happy that he had taken Economics
Honours. I expected him to get a first class which he missed.
But the two years in the College after I joined I found him
knowcking away all the prizes in the College. But he was also
successful Inter-collegiate debates held in most of the city
After he passed out, under the advice of my friednd the late
Mr.M.Varadarajan who was also my colleague he was recommended
and taken as Sub-editor of one of the dailies run by the Rajah
Sahib of Bobbili who was then the Chief Minister of the Madras
Government. Thus Mr. Annadurai came into politics and got imbibed
in the principles of Justice party and also under the influence
of the Self Respect Movement of Periar E.V.R. who had taken
over the leadership of the Justice party in 1937 after the defeat
of the Justice Party in the elections.
Mr. Annadurai proved an able lieutenant of E.V.R. during the
Anti-Hindi Movement. A good student and a clear thinker Mr.Annadurai
was able to develop his thoughts not only on the social side
but also on the political side.
In the forties Mr.Annaduarai seemed to have realized that the
Tamils in an All India set up may become second class citizens
if the consciousness of the people were not roused to the impending
danger and also realized that mere social revolution would not
put the Tamils into the place which they deserve.
This is the time when the greatness of ancient Tamil Civilisation
and Culture should be made known to the people who were quite
ignorant of the greatness played by Tamils in the history of
this great sub-continent which had been knit into a single country
by the British through their administrative and educational
A new renaissance in Tamil Literature and investigation in Tamil
history had made the people of Tamil Nadu to feel that they
had a past which was not inferior to topple like the Egyptians,
Greeks and Assyrians. We owe all this to the revolution started
by Periar E.V.R. and his able assistant C.N.A. who was then
known as "Thalapathy".
But the time Independence came to this country in a way which
very few countries had achieved from foreign domination, C.N.A.
realised that a movement which only dealt with social ills of
the country is not enough and he branched into as D.M.K disagreeing
with the apostle of Dravidian Movement, he started the D.M.K.
which took a definite political colour and yet waited ten years
before he appealed to the electorate in 1957.
From 1957 onwards the leadership of D.M.K. was ably managed,
that step by step people began to realize that at least in Madras
there is a party which is capable of forming an alternative
government to the congress. The astute was in which C.N.A. was
leading his followers and the political basis of this party
that equality of opportunity alone would usher in true democracy
in the country have so convinced the masses that in 1967 the
D.M.K. was returned with a fair majority to the Assembly.
The success of C.N.A lies in the fact that starting as a movement
ot remove social evils and to make people more rational he had
slowly taken the movements to the political arena. Starting
with an independent Dravidasthan which originally included the
four South Indian States, C.N.A realised that the unity of the
Dravidian States as a whole may not be practical politics; so
he gave up the demand for Dravidastan while sticking to his
opposition to imposing Hindi on the South.
Political opponents attributed that the leaders of the D.M.K.
got cold feet and gave up the demand for Dravidasthan. It was
not cold feet but true statesmanship and diplomacy that brought
about the change in the party plank. He was an intellectual
from the beginning, never dogmatic and always willing to think
ahead. The seed of greater autonomy for the states was sown
by C.N.A. and now we are finding the most states are clamouring
for greater autonomy and the establishment of a true Federal
Further the greatness of C.N.A. lies in the fact that his party
is not torn by internal discord and quarrel among the leaders
and also due to the fact that having had no experience of any
kind in the past, the ministry as a whole had functioned in
a way to get the appreciation of outside world.
The administrative ability shown by all the ministers have to
be admired and the way the Chief had guided them and in the
way the Chief had knit them into a single-minded unit show the
genious that he is.
Born not well-to-do, striving hard throughout his life as a
poor journalist, then branching as the Editor of an independent
weekly, Dravida Nadu, then entering the field of drama and authorship
in writing like Bernardshaw with a political emphasis exposing
all the social evils, C.N.A. had proved to the world that his
period would mark a definite era, may I say, the Nair Theagaraya
Era Followed by E.V.R. Era and now Anna Era. This period may
take us the Tamils to a glorious future which may shine as bright
as the Pallava and Chola periods had done and establish a second
millennium in the History of the Tamils.
| இலக்கியம்
| அரசியல் | வரலாறு
| புகைப்படங்கள் | பேரவை
| தொடர்புகொள்ள
Designed by R.Sembian, Anna Peravai


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"Ron is a talented and driven leader who brings a wealth of enterprise software experience to the delivery of healthcare information technology," said John H. Capobianco, president and chief marketing officer at MEDecision. "Continuing on our accelerated growth path, MEDecision is confident that Ron's appointment will help to properly position MEDecision not only for today, but for our continuing success in the area of collaborative care management software."
MEDecision focuses on delivering collaborative care management solutions, both on its own and through its CollaboraCare Consortium, which now includes 15 member vendors that address information deficiencies in health care delivery. The company's extensive experience in the development of payer-based health records helps managed care organizations and emerging RHIOs provide the much needed clinical data exchange at the point of care. This collaborative information delivery assists their provider networks and members in continuing their efforts to reduce errors, enhance treatment opportunities, improve outcomes and provide more affordable healthcare.
As chief information officer, Nall will oversee MEDecision's information technology operations including development and delivery of new and emerging technologies. As a member of the executive team, he will help improve business operations and IT efficiency within the company.
Immediately prior to joining MEDecision, Mr. Nall, as a consultant, provided product management and customer support services to a wide variety of Fortune 1000 companies. Previously, he was executive vice president of services and product delivery for SynQuest, Inc., where under his direction, the support and maintenance team maintained a 95+ percent customer retention record while introducing five major software products. Mr. Nall's extensive experience also includes executive IT positions at PowerCerv, Datalogic International and Computer Associates International, and key posts with UCCEL Corporation, Texas Instruments and Electronic Data Systems. He holds an MBA and BS in Management from the University of West Florida.
Complementing Mr. Nall in their respective areas of accountability, several MEDecision executives have assumed increased responsibilities and recently received the following promotions:
-- Terry Beck, vice president, sales
-- Mary Boyle, vice president, product management
-- David Comiciotto, vice president, corporate quality
-- Tracey Costello, vice president, corporate marketing
-- Dennis Johnson, vice president, finance
-- Danielle Russella, executive vice president, sales
-- Kristel Schimmoller, senior vice president, product marketing
-- Mary Jo Timlin-Hoag, senior vice president, client operations
About MEDecision
MEDecision is a leader in collaborative care management. Founded in 1988, the company's software solutions create a seamless payer-based medical management system to analyze, apply, administer and automate the management of healthcare programs, and provide a common patient view at the point of care. This common patient view is powered by MEDecision's clinically validated payer-based health record, a comprehensive source of broad patient medical information, and an effective step toward the Electronic Health Record that is central to the coming revolution in health care information technology. MEDecision's customers manage the care of approximately one in every six Americans with health insurance. For more information about MEDecision, please call 610-540-0202, email firstname.lastname@example.com or visit www.MEDecision.com.
MEDecision is a trademark of MEDecision, Inc. The MEDecision logo and product names are also trademarks or registered trademarks of MEDecision, Inc. Other products and brand names are trademarks of their respective owners.


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Alia and Dina Al-Abd are sisters and founders of WeddingHubEG; the first and largest destination for all matters related to weddings in Egypt. The two sisters had one dream and together they worked hand in hand until they transformed this dream into reality. We met them over coffee to hear all about their exciting start-up and how they made it happen.
What was the inspiration behind WeddingHubEG?
Alia: The story goes back to 2015, when one of our closest friends was about to get married. We witnessed and had first-hand experience with the big hassle of trying to plan a wedding. Finding the RIGHT wedding professionals, setting appointments, arranging payments, and not to mention the actual execution of the wedding could all get extremely hectic. Without professional guidance, the bride and groom to be could get lost and overwhelmed. A light bulb came over our heads then; it was to create a website that guides couples throughout the process of planning and executing their wedding. We aimed for the website to be their one-stop guide to their big day.
How does WeddingHubEG.com work?
Dina: WeddingHubEG.com is designed to provide brides and grooms with all the wedding planning details and tools there is, which will make their life easier and will help them be in control of their day. The website is extremely easy to use and is divided into three parts; the first part is Browse Listing, where couples can browse wedding professionals from wedding planners, fashion designers, photographers, make-up artists…etc. The second part is Planning Tools, the budgeter and the checklists that have been developed based on the input of more than 100 bride and grooms to be. These tools, depending on the couple's input, such as wedding date and planned budget, will provide them with a monthly guide that covers all the wedding tasks and details, and will break down their budget in order for them to know what to spend on each category. Last but not least, the third part of our website is the blog; our newest addition that covers all the tips and tricks couples would need throughout their wedding journey, as well as new and exciting "insider" wedding information.
Give us an example why using WeddingHubEg.com can be really effective.
Dina: The keywords for a successful wedding are comfort and confidence. Comfort that the wedding professional the couple picked knows what the couple wants, and confidence because they trust this vendor to deliver what the couple expects from them. So instead of couples spending hours and days looking for the right vendors for their wedding, and then spending some more contacting them, setting appointments and a host of other details, we did all the research for them, and took the weight off their shoulders. All they have to do is browse the website where they will find the top wedding professionals in Egypt, ranked, with pictures of their work, their contact information, and their social media platforms… all in one place. Furthermore WeddingHubEG.com offers a highly interactive experience where couples will find unique reviews about vendors shared by their previous clients and they can share their experiences as well. And that's how you choose your favourite vendors.
What are the challenges you faced to launch WeddingHubEG.com?
Alia: Launching a brand new and inventive idea was very challenging, no doubt about it. Breaking new ground always is. Some of the vendors we contacted before launching the website didn't believe in our idea and never thought that it would succeed or see the light of day. But we didn't let this stop us; we believed in our purpose and ourselves and kept going. After a lot of hard work and dedication, the website came to life and the vendors were surprised and amazed by how we executed the idea. Now it's been almost a year that we launched it, and it started raising awareness every since. In addition, another challenge we faced was getting support from people around us, and that's the hard thing about doing something new, and going against the crowd, support will come in short supply. But we got through this challenge as well, and are so thankful to all the people who had faith in us, and believed in our success.
Some quick tips for brides and grooms who are in the midst of planning their wedding.
Dina: Behind every fantastic wedding is a team of top-notch vendors. Bride and grooms to be should hone in on wedding professionals who will mirror and solidify their wedding vision, who are best for the couple's budget, style, and personalities. So communicate with the vendors you prefer in order to know if they are what you're looking for. You can attend an event hosted by the DJ you like, book trial appointments with the make-up artist and hair stylist, join a tasting session at the venue, ask the wedding planner for mood-boards, sketches, and samples. If you feel like you trust this vendor with your wedding, hire them immediately.
On the wedding day, surround yourself with people with positive vibes, capable of comforting you if stressed. Trust the wedding professionals you picked and let them do their jobs to avoid stressing yourself out. It's your day; you shouldn't be fussing over anything other than enjoying yourself. Hire an assistant on the wedding day or delegate close friends to make sure that everything is in place.
WeddingHubEG was your dream that came true, what advice do you give to people to go after their dreams?
Alia: First off, organize your thoughts. The thing about dreams is that they are so big and messy; you have to put them in order so that you can work on making them true, and turn them into projects. Always follow you passion, it's your fuel to keep going and never giving up. Be so generous with your dedication to your dream; put no limit to the amount of work you will devote to it. Surround yourself with positive people, who believe in you, in your project and who will supply you with good vibes when you're feeling down, and when you get tired of the obstacles that will come your way.


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You may think that the location of this weeks drinkup is a subtle way to cast in our lot with a particular side of the age old conundrum, 'Pirates or Ninjas?' It is not. We are an Equal Opportunity Employer and as such we consider applicants for all positions without regard to race, color, religion, creed, gender, national origin, age, disability, marital or veteran status, or any other legally protected status including but not limited to pirate/ninja affiliation. Also, as it turns out, there are no ninja bars. Ninjas if you would kindly rectify this we'll happily meet on your turf next time.
The Facts:
Il Pirata 2007 16th Street San Francisco, CA 94103 February 25th 9pm


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512 Charlotte Street
Fredericton, New Brunswick, Canada E3B 1M2
Our church office hours are Monday to Friday 9:00am to 1:00pm.
For Sunday Worship, limited parking is available in our own small lot behind the church (entrance from Carleton St.), at the PQA Building (231 Regent St. — entrance from Charlotte St. — see map), the Rexel (formerly Liteco) Lot (351 Carleton St. — see map), and the on-street spots along Charlotte St., George St. and Carleton St. (between Charlotte St. and George St. only).
We ask that the two accessible parking spots designated for "persons with disabilities" on Charlotte St. (directly in front of the Church) and the two in the back lot (closet to the building) be reserved for vehicles displaying the standard blue placard.
Winter Parking Restrictions (Nov–Apr): We have been notified by the city police that city by-laws restrict winter parking along some streets near church. The police must enforce these by-laws beginning Nov 1. Please note that there is no parking on Carleton Street between Charlotte St. and George St. Please watch for parking restriction signs in place along other nearby streets.
The Rev. Jon Van Den Berg
Office Administrator:
Tara Cyr
Organist and Choir Director:
J. David Berry, BA (Music), BA (History), MA (Music)
Director of Youth and Young Adults:
Jordan Schriver, BA Psychology (Honours), Current MA/PhD student in Psychology.
Ralph Graves
Other Contacts
Phone or email the church office and the message will be forwarded.
The Rev. Jon Van Den Berg, Moderator
Jeanne Kaye Speight, Clerk of Session
Dallas Davis, Mission, Development & Social Action Committee Chair
Stephen MacKay, Worship Committee Chair
Jordan Schriver, Christian Education Committee Chair
Rose Carolyn Smith, Pastoral Care Committee Chair
John Astle
Jean Boudreau
Sonya Burrill
Mary Charters
Bill Cockburn
Janet Higgins
Jacqueline Howie Cleland
Marg Leonard
Calvin MacIntosh
Kathy MacKay
Andrew Speight
Colleen Watson
Board of Managers:
Brian Barnes, Chair of the Board
Bill Cockburn, Building Committee Chair
Bob Leonard, Finance Committee Chair
Andrew Ottens, Treasurer (email@example.com)
Murray McEachen, Secretary
Jeremy Burrill
Max Cater
David Charters
Alex Cummings
David Fraser
Carol McEachen
Andrew Speight
Church School Superintendent:
Terri Astle
Ladies Group:
Kathy MacKay
Children's Choir:
Kathie Berry
Ministers Emeriti:
Rev. Doug Gordon
Rev. Dr. Basil Lowery
Elder Emeritus:
Hollie V. Craig


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This webpage discussess overall strategies for advisement of students with learning disabilities as well as general advising principles for working with students with disabilities. A few factors are discussed which include course balance, time and distance, and selection of major. A link to the entire advising handbook is provided.
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