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Miles M. Ishigaki began playing the clarinet at the age of 10 in his home town Honolulu, Hawaii. Later, he moved to Norman, Oklahoma, where he earned his Doctorate of Musical Arts in clarinet performance. Ishigaki is Professor of Music at California State University, Fresno (CSUF), where he has taught applied clarinet, chamber music, music theory, and music appreciation since 1987; as well as being the director of the university clarinet choir. Since 1989, he has served as state chair for the National Association of College Wind and Percussion Instructors. His gifted college and pre-college single-reed students have won awards in international clarinet competitions, and have been participants in prestigious regional and national honor wind ensemble festivals. In addition, students from his studio have received numerous prestigious academic awards including the Ronald E. McNair Doctoral grant, President's Equity Scholar, Sally Cassanova Doctoral grant, Stanford University internship, Fulbright Scholarship, CSUF President's-Rodman Scholarship, CSUF President's-Rodman Graduate Fellowship, University of Oklahoma Graduate Fellowship and UCLA Doctoral Fellowship.
Ishigaki has taken part in many performances with such groups as the Fresno Philharmonic, Oklahoma Symphony, Fresno Lyric Opera, Orpheus Chamber Ensemble, Fort Collins Symphony and the Greeley Philharmonic. His enthusiasm for the solo and chamber repertoire of the clarinet has resulted in his giving of numerous concerts in the United States, England, Mexico, and Japan; being a guest soloist and lecturer at the Oklahoma Clarinet Symposium; and directing special arts projects for the CSU Summer Arts Program. He also shares his musical talents through performances for community organizations such as the American Red Cross, Valley Children's Hospital, Friends of the Fresno Public Library Series, the Central California Nikkei Foundation and the Japanese American Citizen's League.
Ishigaki has studied clarinet with David Etheridge, David Harman, Loren Bartlett and Stanley Shimada; who are all distinguished teachers that have been closely aligned with prominent clarinetists of the United States such as Stanley Hasty, Himie Voxman, George Waln and William Gower. A lively interest in all aspects of the art of performance is a quality that Dr. Ishigaki brings to his research projects that include Inspired Accidents: The Interaction of Intuition and Analysis in Teaching Music Performance; Artistic Performance: Developing an Understanding Between the Art and Science of Practice and Performance; and Stravinsky's Three Pieces for Solo Clarinet: Interpretations by Great Artists. His research documents intimate experiences and insightful views of musical interpretation by renowned clarinetists such as Larry Combs, Stanley Hasty, George Silfies, Leon Russianoff, Guy Deplus, Anton Stalder, Alan Hacker, Teruaki Matsushiro and Chun-Xiao Tao. Ishigaki's collaborative research with Dr. Michael Rogers, an author and expert on music theory pedagogy, highlights the relevance of music theory and music performance.
The founder of the West Coast Clarinet Congress, Ishigaki is an active entrepreneur serving as COO of I&M, Inc., a company that specializes in sustainable technology water, housing, and energy. A 2013 Provost's Teaching Award in Technology from Fresno State and a 2006 Honorary Alumnus of the University of Northern Colorado are awards he has received.


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Pride And Prejudice 6 Essay, Research Paper
Pride and Prejudice: Is it possible?
The novel Pride and Prejudice, written by Jane Austen during the nineteenth century, describes the trials and tribulations of five sisters of marrying age. The story is based in England around the turn of the century, and upon careful review, we find that many of the events do not reflect the time period. The relationship between Elizabeth and Darcy, and the Lydia-Wickham affair, are not realistic. Despite the fact that the novel is fiction, it is questionable that such events could take place.
When Darcy first lays eyes on Elizabeth after she is pointed out to him by Bingley, his statement is not that of love, nor of fondness, rather it is one of complete disgust.
She is tolerable; but not handsome enough to tempt me; and I am in no humour at present to give consequence to young ladies slighted by other men.
From Darcy s reaction, we can only imagine what he really thinks of Elizabeth, but we are given a very good idea. This is not love at first sight, there is no attraction between the two, there is nothing at all.
Elizabeth has an equal reaction to Darcy. When she overhears the comments he has made about her, she is anything but drawn to the man.
Mr. Darcy walked off; and Elizabeth remained with no very cordial feelings towards him.(pg.12)
The two seem destined to become worst enemies, in fact they seem to become anything but a couple in love, which is exactly what they end up to be.
Soon after their original meeting at the ball, Elizabeth and Darcy s paths cross again. This time it is at the home of the Bingleys where Darcy is staying, and where Elizabeth comes to visit Jane, her ill sister. When Darcy see her this time, his reaction to her is quite different:
he was forced to acknowledge her figure to be light and pleasing; and in spite of his asserting that her manners were not those of the fashionable world, he was caught by their easy playfulness.(pg.22)
I find it hard to believe that his impression of Elizabeth could change so drastically within a matter of days. Elizabeth, on the other hand, has a more reasonable reaction. She made no notice of Darcy s reaction.
perfectly unaware; to her he was only the man who had made himself agreeable nowhere, and who had not thought her handsome enough to dance with.(pg.22)
Elizabeth s reaction is believable. It is the reaction that I myself might have. While Elizabeth stays quite distant from Darcy, Darcy finds himself more attracted to her. By the end of the evening Darcy has grown quite attached to her. While sitting quietly, Miss Bingley asks Mr. Darcy what he could be thinking about so intently. His response is one that surprises Miss Bingley:
My mind was more agreeably engaged. I have been meditating on the very great pleasure which a pair of fine eyes in the face of a pretty woman can bestow. Miss Bingley immediately fixed her eyes on his face, and desired he would tell her what lady had the credit of inspiring such great reflections. Mr. Darcy replied with great intrepidity, Miss Elizabeth Bennet. (pg.25)
Am I to believe that Mr. Darcy has grown from being mildly disgusted by Elizabeth s presence, to being madly in love with her? It all seems quite unbelievable.
More unbelievable is Elizabeth s changing reactions to Mr. Darcy. Once annoyed by his presence, hurt by his rejections, she too finds herself becoming more attracted to Mr. Darcy. While her realization takes much longer than that of Mr. Darcy, it happens just the same.
Elizabeth does not devote her full attentions to Mr. Darcy, and she does have some distractions along the way, mainly her attraction to the mysterious Mr. Wickham. But after all is said and done, Elizabeth always turns back to Mr. Darcy and his allure. Elizabeth never confirms her attraction for Darcy, never comes out and says that she loves him. When Mr. Darcy proposes to her she turns him down.
In vain I have struggled. It will not do. My feelings will not be repressed. You must allow me to tell you how ardently I admire and love you. Elizabeth s astonishment was beyond expression. She stared, colored, doubted, and was silent.(pg.160)
Despite the fact that Mr. Darcy s proposal is refused, his declaration of love forces Elizabeth to confront her true feelings. Elizabeth keeps any and all feelings towards Darcy to herself, never revealing how she truly feels. This all changes, however, when one afternoon Elizabeth is paid a visit by Lady Catherine de Bourgh, Mr. Darcy s aunt. When questioned about her feelings towards Mr. Darcy, Elizabeth is forced to admit how she truly feels.
Whatever my connections may be, said Elizabeth, if your nephew does not object to them, they can be nothing to you. Tell me once for all, are you engaged to him? . . . I am not Lady Catherine seemed pleased. And will you promise me never to enter into such an engagement? I will make no promise of the kind.(pg.297)
Despite her previous statements, Elizabeth does have feelings for Darcy. These are not just feelings of attraction, she has fallen in love with him; something that had previously seemed impossible. And as many stories end, Elizabeth and Darcy profess their love and live happily ever after in his castle on the hill. Yes, it is a happy ending, but is it realistic. How can two people grow from hating each other to falling in love? It is something that does not happen in real life.
Another event that I find to be beyond belief is the Lydia-Wickham affair. Lydia Bennet, Elizabeth s younger sister, runs away with Mr. Wickham a man twice her age. Despite the apparent age difference, and the fact that Mr. Wickham has a history of running away with younger woman, Lydia still runs away with him. It is not the event that I find so unbelievable, as it is perfectly fathomable for a young girl to think with her heart and not with her head, but rather the family s reaction to the event. This is a very serious event. Often times the man would run away with the woman, refuse to marry her, use her, and then leave her. The man would usually be unscathed; the woman however would have her reputation destroyed, be disowned by her family, and with no other option, end up being a prostitute. It is a life altering event. I find it hard to believe that Ms. Bennet is so desperate to have her daughter married, that she is willing to except her running away with an older man. It isn t realistic. Elizabeth is the only one who s reaction seems fitting. She is horrified at the match.
Brother-in-law of Wickham! Every kind of pride must revolt from the connection. He had to be sure done much. She was ashamed to think of how much.(pg. 272)
The rest of the family has a different opinion. They are very accepting, and welcome Lydia with open arms. It almost mocks the seriousness of the event. The family s reputation would have most surely been ruined, and yet they welcome their daughter back? I find it to be very unbelievable.
While Pride and Prejudice is a wonderful book, and it gives us insight into the mannerisms of the nineteenth century, there are many events that I find to be unbelievable even 100 years later. The relationship between Elizabeth and Mr. Darcy adds to the fantasy aspect of the fiction novel, but again we are forced to question whether these events are possible. If Elizabeth and Darcy did not fall in love, would we be left wanting them to be? Would we feel something is missing? The Lydia-Wickham affair is completely unbelievable, and it is discussed to lightly to be realistic. The family s reaction is not one that would normally be expected. As unrealistic as the book seems, it may be that The Victorian Era in which the book was set, is so different than the world today, that short of becoming a historian, there is no way that I could fully understand the characters and their motives.

subset: commoncrawl


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|Message view
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|Liu fuming <liufm3...@qq.com>
|Re: problems with shared nothing Master/Slave deployment
|Tue, 13 Nov 2012 09:06:14 GMT
First,the sendFailIfNoSpace problem.This expression context.isNetworkConnection() returns true, so the systemUsage.isSendFailIfNoSpace() method become uesless. Second, consumer don't receive messages. I sent some big messages to full fill the KahaDB store,and the thread is block in the Queue.waitForSpace() method.Then I added 5 consumers to the brokers,the master finished its work ,and sent the ConsumerInfo command to the slave.The slave didn't react until I changed the value of variables in waitForSpace() method to make it get through. After that OpenWireFormat.unmarshal went on to unmarshal the ConsumerInfo command. -- View this message in context: http://activemq.2283324.n4.nabble.com/problems-with-shared-nothing-Master-Slave-deployment-tp4659224p4659229.html Sent from the ActiveMQ - User mailing list archive at Nabble.com.
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|July !!! And, not only is is it July already but we have already put the big 4th of July holiday behind us already and as you guys are reading this, we are incredibly entering the second week of the month already ! Is this summer flying by or what ? It is just a total blur for me. Eat, sleep, fish... rinse & repeat.
|So fishing this past week for us aboard "The Trophy" has been back to pretty much awesome once again. We made all of the necessary adjustments this past week and have simply followed the fish offshore. We've also changed our program over to the deep water summer techniques that has worked for me for almost three decades now. It's almost comical to see so many boats just now trying to perfect their Jet Diver and other shallow water techniques. Man, that part of the season around here is over with. And when it's over, it's really OVER ! We have now ourselves moved on to the wire line and crank bait program and it is working pretty much to perfection ! And I don't mean maybe!
|We had many memorable and productive days this past week. We caught plenty of fish and many of those in the "trophy" and "fish of a life time" category. Saturday my guys had a big fish contest amongst themselves and I was the designated judge in charge of measuring them. The very first three fish that made it to the boat in the morning that I measured went a whopping 29", 29 1/4", & 29 1/2" which ultimately was the big fish of the day. Not a bad way to start the day! Or my boys from Iowa that fished with me two days Thursday & Friday and went on to take home 125 pounds of pure fillets for their two days effort! Just many, many success stories this past week.
|What will this new week bring? I am sure many new unforgettable memories. Peoples first Walleye ever, peoples biggest Walleye ever, the most Walleyes they ever caught, their first Steeelhead... On and on. I will hear lots of hooping and hollering and that I am sure of. And through it all, I will calmly say, why its just "another day on The Trophy !" lol ! See you guys next week.
Capt. Walt
*We are entering this part of the season now where it is imperative that we get out very early in the morning. With the very clear water out there, we usually get a strong morning bite before the sun gets up too high and the action drops off significantly. WE DO NOT WANT TO MISS OUT ON THIS OPPORTUNITY ! Until further notice, we are now departing from the dock everyday at 5am sharp. Please if you have a trip scheduled, be here early and be ready to roll at such time ! Also, MAKE SURE YOU HAVE YOUR FISHING LICENSE ahead of time. There are no license sales at the marina. If you are getting just a 1 day license, make sure to get the 1 day "charter license" which only goes into effect if you actually get out and use it. Links on my website for online sales. Any questions, call me.


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Ireland! Baseball!
Short notice, I know, but we just found out about this last night.
There is a movie about the formation of the Irish National Baseball Team (!!!) playing at the Lagoon theater this weekend, for two showings only! Tonight (Friday) at 7:30, and tomorrow (Saturday) at 2:00. Mr. TBL and I will be catching tonight's showing. Drop me a line if you'd like to make a group of it.
More on the movie:
The Emerald Diamond
and also check out the Irish National Baseball Team's official site:
Baseball Ireland


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Monopoly - Steam Gift (PC)
- Availability unavailable
- Delivery Time 1-24 hours
- Language English
- Platform PC
- Version Region Free
Monopoly - Steam Gift (PC)
The PC version of classic board game, Monopoly gives players new ways to play as they challenge their friends.
Buy Monopoly - Steam Gift (PC) and get your link for Steam activation within minutes via email! Use the link to access your highspeed download of your received game.
Don't miss out this offer, buy Monopoly - Steam Gift (PC) now
About this game
Own it all in the classic property trading game! Build your fortune as you buy, sell and trade the world's most famous properties. It's classic MONOPOLY fun! Take a ride on Reading Railroad, build a house on Baltic Avenue, or buy up the whole neighborhood — it's your turn to get rich! You'll take a spin around the world's favorite board with animated tokens, 3-D dice and customized game environments. Prove your skills as a deal maker in up to three levels of difficulty. Pass GO, take a Chance or head over to Community Chest as you wheel and deal your way to the top. But remember to stay out of Jail! Are you ready to own it all?
Enjoy classic MONOPOLY play. Buy, sell, trade and manage famous properties. Play with animated tokens, 3-D dice and customized game backgrounds.. Choose from 3 levels of difficulty. Explore "House Rules" to play with a twist.
The most famous board game of all time is now here for you to enjoy in video game format! We all know Monopoly, but now, you can play the game without having to worry about arranging the money, making sure you know all your properties and what they are worth, and all the other little things that can make board games a hassle to manage. With the Monopoly PC version, the game takes care of all that for you!
So, how will you play the digital version of the game? Will you play the classic experience and relieve the memories you had with your family? Or, will you play with your friends in various modes that'll challenge what you think you know about the game? Whatever you decide, it's up to you to have fun and make sure you win the game!
Note: Multi-player is hot-seat multi-player only. Online multi-player is not supported.
System Requirements
- OS:Windows XP SP3/Vista/7
- Processor:1.4+GHz
- Memory:2+ GB RAM
- Graphics:256+MB
- DirectX:9.0c
- Hard Drive:1+ GB HD space
- Graphics:512+MB


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The Innovator's Dilemma — Even top notch leaders of the most successful companies will eventually be forced to make decisions which will seal their fate. Should the company continue to comfortably market a popular product obsessively, or should it focus on disruptive technology that will change the future?
There's an adage which will always carry a lot of weight. The customer is always right. However, while your customer may always be right, your customer will never always stay satisfied. Consumers are always on the lookout for a new product which is better than the last one. The next bestselling product will be better suited to match their taxing demands.
Bestselling author Clayton M. Christensen addresses "The Innovator's Dilemma" and how markets get changed in the process. In today's rapidly changing evolution of technology, there's only one thing to be certain of — and that is change.
Christensen made the term disruptive technologies famous in 1995. What is disruptive technology? Disruptive technology is nothing short of pure innovation. It's when a prodigy realizes that innovation will spark a new market and in the process will disrupt the dominant, existing market.
Sometimes change can happen within a generation. Change can happen almost overnight in some instances. There's one variable that will remain — the inevitability of change. It's part of the fluctuating economic cycle.
In his bestselling book, Christensen gives us the nuts and bolts of the business cycle itself. He gives us prime examples of where the biggest of companies have succeeded, while others have failed adequately. You'll be surprised upon reading the book and discovering how certain household brands have established themselves, while others have completely vanished away.
The innovative developments of our day will astonish you if you stop and get a glimpse of the procedure. Executives are often forced into complying with closed, rigid systems. They also have to deal with profit margins.
What is obscure to the average consumer is that firms do frequently stumble when confronting technology. Executives do struggle with innovative technology, because they have to continually satisfy the hunger of their stockholders. But if that market eventually dries up, and it does happen, your company will cease to exist.
There's a famous quote that describes one version of the leader's struggle:
You can always tell who the pioneers are because they have arrows in their back and are lying face down in the dirt.
Christensen argues that while this thinking is conventionally popular, leadership roles are far more complex and timing is one of the most critical elements of any maneuver. While it is true that executives are only human and they do make mistakes, it is the brilliant ones that do the research and understand the profound impact of innovation.
Christensen evaluates the advancement of computer technology, retail, construction, and more.
The data he provides in the book relates to companies that have become synonymous with success. These are brands that are very recognizable; and they have left an enormous impact on societal function, as well as sociological behavior.
Human behavior is very difficult to predict; it's even more difficult to market. Due to our hectic schedules, we seldom think about how companies evolve. In addition, we often fail to realize how their decisions affect our daily lives.
Christensen concludes that companies can thrive if they plan ahead, look for patterns in the market, and invest their time into doing adequate research.
For those companies that are capable of facing the vigorous challenge, they will be granted with the highest levels of achievement. The profits are much greater for those that are first in line. The risk is equally as great.
There's a challenge that many successful companies will have to confront sooner or later. That decision is to remain with sustaining technology, or embrace disruptive technology. It's "The Innovator's Dilemma".


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Whether you're bearing down on the end of this semester or you're looking to prepare for the next one (the latter is even better), you know that time always comes around: finals week. Yet, it doesn't have to be a stressful and hurried time. Here are ten tips to prepare for your final exams.
1) Ask Questions and Request Help When You Need It.
- Talk to your classmates who clearly master the material and see if they'd be interested in helping you study. For many people, teaching something is also a great way to solidify their knowledge, so it's a win-win situation for you both. Don't be afraid to ask classmates or friends who have already succeeded in the class to help you study for finals.
- If you have teaching assistants, take advantage of their availability to ask questions. Approach them before or after class, or visit them during office hours.
- Instructors have regular office hours to ensure that they are available to students. If your schedule conflicts with the instructor's office hours, e-mail him or her to set up an alternate time. Instructors are there to help you understand the subject, and by asking questions you show them that you care about the material – and your grade.
2) Be Involved From Day One.
Keep up on readings and assignments throughout the semester, minimizing the time needed to prepare for finals. Attend class punctually and regularly. While you may be able to borrow a friend's notes if you miss a class, it does not compare to being consistently present.
3) Don't Just Study Hard – Study Smart.
For each subject, make a list of the material and the chapters that you've covered in the course. Consider how difficult each chapter or type of material was for you and write your evaluation next to it (easy, somewhat difficult, extremely difficult, etc.). This will help you determine how much time you should spend on each chapter or area of the material. It is also useful to study the hard things first, because that way you have more time before the exam to address particular difficulties or areas you really need help with.
4) Study with a Friend or Group.
Do not wait until the last minute to form study groups. Somewhat early on in the semester, approach classmates with the idea of forming a study group. It is ideal to have at least three people, in case one person backs out – but not more than 5 since it becomes difficult to coordinate. Organize your study groups now and do a few practice sessions early to go over class notes and areas that should be covered. You will all feel ahead of the game if you start your study groups now. Knowing that others depend on you (and vice versa) is a great method for reducing stress and increasing your motivation to study.
5) Don't Cram – Start Early.
Do yourself a huge favor and start studying early on in the semester. Spend at least one hour per week reviewing class notes. Highlight all the areas that are important, and look back at the syllabus to narrow down the key areas you'll need to get a handle on. By simply going over all your class notes, you'll get a good overview of the specific areas you should start studying. This will also provide your mind with a good summary of everything you've been learning this semester.
6) Make a Plan and Stick to It.
Make a commitment to spend at least an hour a week (per class) to focus on the final exam. By setting aside time now to focus on the final exam, you're preparing your mind for what's ahead. You will come across material that you have questions about, and this way you have plenty of time to get answers from your instructors. By reviewing early and often, you'll simultaneously prepare for finals and midterms.
7) Spend Time Studying for the Tests that Matter Most.
Not all final exams and papers are weighed the same. Take a look at the syllabus of each course you are taking and assess how you are doing overall in that course. Make sure you know what percentage each paper or final exam is worth to your grade. This will give you some perspective on how much time you should designate studying for each class.
8) Take Appropriate Care of Your Health.
It is extremely important to maintain good health in order to do your best in school. Exercise regularly and set aside time to take breaks from studying and working. Make a point to relax with friends regularly and participate in non-academic activities to avoid getting burned out. Eat healthy foods to keep you energized and focused. Stick to a regular sleep schedule. This is particularly important in the days and weeks preceding finals week. Pulling all-nighters can easily result in a low grade because being tired significantly affects your attention and comprehension.
9) Respect Your Personal Habits and Abilities.
In other words, what do you have to do to be your best? This involves several aspects:
- What time of day are you more focused? If you are bright and fresh in the morning, then that is the best time for you to study. However, if you are a night owl and find more energy post-dinnertime, then that's when your brain is ripe to soak up information. Respect how your body clock works and use it to your advantage when studying.
- How much studying do you really need to master the material? Do you start to zone out when study sessions last more than 2 or 3 hours? If so, then schedule more frequent sessions that last shorter amounts of time. If however, you do your best and really get rolling after an hour or so, then schedule a whole day away from other distractions so you can concentrate fully and progress.
- Do you study best alone or with a group? By giving self-tests or simply re-reading the material? Or perhaps in a combination of ways? Try various tactics and see how they work for you. Then be sure to stick to them appropriately in order to really do your best.
10) Don't Stress.
Rather than being worried and stressed, be proactive and calm. Plan well, structure your time appropriately, and believe in yourself. When you have difficult moments, take a walk or breathe deeply. Take a catnap to refresh, or relax with a cup of tea and a good book. Remember that feeling calm and centered will allow you to bring out your best for the final!


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Organizers of the "Occupy Central Movement" civil disobedience campaign scheduled for July have staged a mock voting exercise on Sunday, in rehearsal for a civil referendum to be held on June 22 to illustrate Hong Kong people's preferences on the candidate nomination methods for the 2017 Chief Executive election.
Around 100 people participated in the mock voting exercise, with nearly 80 percent of the voters supporting a proposal put forward by the education sector which will allow public nomination, the Hong Kong Economic Journal reported Monday.
Organizer of the movement, Benny Tai, said the result of the mock voting has been predictable, as most of the voters were from the pro-democracy camp. However, he said he would like to see a greater level of diversity in the poll outcomes.
Tai's group will hold a discussion session on Tuesday and will vote for the top three election methods out of the 15 that are available now, for the public voting on June 22.
Tai added that there is no fixed timeline for the Occupy Central Movement, as it will depend on the government's response on the electoral method.
Financial Secretary John Tsang wrote on his online blog that it is worrying that some of the relatively extreme opinions in the universal suffrage debate are not just bargaining tactics, but rather look like giving an impression that they would never back down.
Legislator Alan Leong, a member of the Alliance for True Democracy, said Tsang was stirring up conflict unnecessarily by branding the people as not willing to negotiate, even before the discussions have begun.
Chief Secretary Carrie Lam said the government will consolidate the tens of thousands of suggestions collected during the public consultation period for the Chief Executive election to prepare a report to to the central government, the report said.
– Contact us at [email protected]


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The News and Post are now a government-sanctioned monopoly. Because of that, readers in Colorado feared that their editorial standards would get lower. But, they needn't have worried, they can't get any lower than rock bottom! Keep watching, there are new gems from the sports "writers" daily!
Kiszla said he was through writing about baseball, and we rejoiced. However, the lure of nights of bacchanalian revelry at the World Series in return for a few badly written columns was apparently too much for the shallow drink-seeking missile, who obviously phoned this column in under the influence of something.
October 26, 2005 in the Denver Post
"Whether the roof is open or closed,
the team that scores the most runs tonight will win," major-league official Bob
DuPuy said at dinner time, when everybody was fresh.
"Very good point," commissioner Selig agreed.
Actually, both distinguished gentlemen were dead. (This is the classic three-strike situation, because these guys are not distinguished (1), not gentlemen (2), and certainly not dead (3). The Observer wishes he knew what Kiszla meant, but doesn't care enough to inquire.)
Same article, apparently submitted too late to proofread.
October 26, 2005 in the Denver Post
No wonder television ratings for the World Series are steadily declining toward the same audience level attracted by "Elmidate." (We think he meant "Elimidate").
When many sensible adults around the country began walking the dog or
flossing, Houston was blowing an 4-0 lead in the middle innings. (We would have
said "a 4-0 lead".)
Kiszla said he was through writing about baseball, and we rejoiced. However, the lure of nights of bacchanalian revelry at the World Series in return for a few badly written columns was apparently too much for the shallow drink-seeking missile, who obviously phoned this column in under the influence of something.
October 26, 2005 in the Denver Post
"Whether the roof is open or closed,
the team that scores the most runs tonight will win," major-league official Bob
DuPuy said at dinner time, when everybody was fresh.
"Very good point," commissioner Selig agreed.
Actually, both distinguished gentlemen were dead. (This is the classic three-strike situation, because these guys are not distinguished (1), not gentlemen (2), and certainly not dead (3). The Observer wishes he knew what Kiszla meant, but doesn't care enough to inquire.)
There is no excuse for printing inaccurate information, no matter where it comes from.
August 4, 2005 in the Denver Post
In today's Post Sports Section, in describing the Philadelphia Phillies victory over the Chicago Cubs, the Post printed that the winning run scored on a passed ball. The box score on the previous page, however, shows no passed balls by either side. The winning run actually scored when Jimmy Rollins of the Phils stole home after Cubs catcher Michael Barret threw the ball to third trying to pick him off. Granted, the story was a feed from the Associated Press, but you would think that someone at the Post at least checked the stories for accuracy before blindly printing them, wouldn't you?
A later AP story described the play thusly: "A mental mistake by Michael Barrett allowed the winning run to score in the ninth inning Wednesday night, and the Cubs lost 4-3 in Philadelphia. Barrett had Jimmy Rollins trapped between third and home after Pat Burrell struck out with the bases loaded, but the catcher threw to third too soon, giving the speedy Rollins an opening to dash to the plate. Burrell swung and missed wildly on a full count for the second out, but Barrett couldn't handle the pitch cleanly and was charged with a passed ball. Rollins broke for home when the ball squirted away, then stopped about 40 feet from the plate as Barrett picked it up. But after the rushed throw to third, the return toss from Aramis Ramirez was too late."
The corrected account also mentions a passed ball, but it obviously did not result in the winning run being scored.
Somebody lost about $50,000...
August 3, 2005 in the Denver Post, by Troy E. Renck in
the "rockies notes" column
The Rockies sent $150,000 to Baltimore to complete the Byrnes deal. Red Sox president Larry Lucchino offered to pay half, which Monfort refused. (See below.)
August 1, 2005 in the Denver Post also by Troy E. Renck in article entitled: Boston reneges, burning Monfort
"We felt it was a formality," said Monfort, whose Rockies also sent about $200,000 to Baltimore to complete the Byrnes deal.
May 9, 2003 in the Denver Post by Mike Klis
"the Phillies make their only visit of the season to Coors Field for a three-game series, Friday through Sunday." (Klis, who can pack more mistakes into an inch of newsprint than anyone in history, didn't bother to check the schedule or he would have seen that it is a 4-game series, through Monday. I guess they still can't afford proofreaders at the Post. ed)
July 13, 2003 in the Denver Post by Troy Renck
"But after the Rockies' fourth consecutive victory, after they moved to within four games of the Philadelphia Phillies in the National League wild-card chase, talk centered on Preston Wilson's catch of the day, if not the season." (Troy almost never checks his facts and apparently the paper doesn't either. When this was printed, the Phillies were 4 and a half games ahead and the Rockies had actually lost ground, because the Phillies had won 5 in a row. ed)
June 6, 2003 in the Denver Post by Troy Renck
"It went unsaid, but it's worth nothing: The Rockies moved a game above .500 for the first time since May 4..." (Proof once again that Denver newspaper writers don't even bother to read their own stuff before it goes to print. ed)
March 8, 2003 in the Rocky Mountain News
"A is for Armadillo. The distance between baseball's spring training camps is measured by the number of dead armadillos along the highway. The Rockies are 14 ½ armadillos from the San Francisco Giants and the gap is widening." Bernie Lincicome in the Rocky Mountain News. (Unless there has been a dramatic change in habitat in the past couple of years, there have never been any (modern) armadillos in Arizona, or west of Texas, for that matter. ed.)
March 8, 2003 in the Rocky Mountain News
"..something the Phillies have done (appeared in the World Series) only three times - in 1915 and 1950, when they lost, and in 1980, when they won." Jack Etkin in the Rocky Mountain News. (You might want to check the record, Jack, you seem to have missed 1983 and 1993. ed.)
December 16, 2002 Denver Post recap of Basketball Game won by Arizona over Texas 73-70.
"Gardner made one of two free throws to make it 70-65 with 57 seconds remaining. Thomas' two free throws cut the lead to 70-67 with 51 seconds to go."
Gardner then drew an offensive foul on Ford and again went 1-for-2 from the line for a 70-65 lead."
"The Angels were initially owned by Gene Autry, who died on Oct. 2, 1991, at the age of 91.
Fregosi said Autry called him every day during the 1993 World Series when Fregosi was managing the Philadelphia Phillies and Lee Thomas, another former Angel, was Philadelphia's general manager." (Autry actually died in 1998. ed..)
"The victory kept the Reds in sole possession of finrst place in the National League."
(I guess this guy knows something about contraction that we don't. ed..)
"In summer 984 he (Larry Walker) played shortstop for Team Canada..."
(After playing for over a thousand years, no wonder he's so good. ed.)
"There is some emotion, but for the most part, you put it all side" said Bobby Estalella, according to Mr. Ringolsby. (We believe he was misquoted. ed.)
"Since I got here, everyone has made me feel welcomed." Ringolsby misquoted Estalella again.
"Now guys are relax and playing with some confidence." Ringolsby misquotes Clint Hurdle. (Mr. Ringolsby once again reached his average of 3 misquotes per day. The team should sue him for making them all look stupid. ed.)
It doesn't matter if they use they're high-paid veterans, or late-developing prospects just called up from Triple-A." (This is from the web site, so they will probably delete it before you see it. ed.)
"Yet, the Phillies approached him (Scott Rolen) again last week about reopening negotiations, and again Rolen turned him down."
"It doesn't matter if
they use they're high-paid veterans, or late-developing prospects just
called up from Triple-A." (This is from the web
site, so they will probably delete it before you see it. ed.)
"Colorado's hitters, those who figure to benefit the least from the change, seem indifferent. As if it's much a humidor about nothing." (Huh? ed.)
"Colorado are 0-7 in one-run games, all on the road."
"...the Rockies are storing their game baseballs this season in a humidor and temperature-controlled room..." So first, they put them in this humidor, then they put it in the room. Or does the room have humidor-control? ed.
While discussing Steve Carlton's 1972 season in which he won 27 games, George Fraser said "What's really amazing is that he won 50 percent of the Phillies' games that year. They won 54 as a team!" It's amazing alright, George, but not that amazing, because the Phillies won 59 games that year. What is even more amazing, George Fraser and Drew Goodman repeated the same misstatement Saturday, April 27th when the Phillies played the Rockies in Denver. More amazing still, they had Steve Carlton as a guest on the following Sunday and asked him if that was his greatest season, when he "won 27 of the 54 games the Phillies won" that year. Even more amazing still, Carlton did not correct them! Does no one from the Rockies or KWGN listen to these guys? They may be the most boring and inane announcers in the world, but someone from their employers should be listening to them - it's their job!
"If we pop Johnson and Schilling, boom-boom, back-to-back, what's that going to do them?" Mike Klis
Following are all from Mike Klis' "It's Bennett to the rescue" article:
"If the home opener is to baseball what "Seinfeld" once meant to NBC, the second home game carries all the appeal of the half-hour economy update on CNBC." Huh?
"By the time Eusebio, Hernandez and Petrick showed what they had, but it was the least-talked about candidate, Bennett, who showed up as the Rockies' starting catcher."
"If people were going to talk bad about them on this night, they weren't going to hear it."
"With two outs in the ninth, nobody on and Arizona leading by a couple touchdowns..."
"After Holmes got his Sosa, Monfort couldn't resist delivering Showalter a dig." Huh?
"Even inside the magnificently successful New York Yankees' clubhouse, the star system exits."
"In this era of multimillion contracts and incredible feats of strengths,..."
"that's why the call it acting," Troy E. Renck, Rockies Notes Column
"...who has longed dreamed of making a cameo in a movie, "I an anxious to see how it turns out." Troy E. Renck Rockies Notes Column
"...but I wouldn't my being behind the camera." Troy E. Renck, Rockies Notes Column
August 30, 2001 Denver Post
"Phillies Likes Norton" (No, theys doesn't)
June 13, 2001 Denver Post:
"For every two-run homer by the Rockies' Todd Helton in the bottom of the first, The Mariners got solo homers in the top-half from Edgar Martinez and Boone.." Mike Klis (an alias for Mark Kiszla?)
For every single one, eh?
June 8, 2001 Denver Post
"Throughout all three periods, Roy never stopped standing stall." Mark Kiszla
Apparently St. Patrick has developed a new defensive technique, the "standing stall". ed.
June 8, 2001 Rocky Mountain News
"The second game today night pits local favorite..."
June 1, 2001 Rocky Mountain News (did the proofreaders quit?)
"... scored to give the Avalanche a 2-1 lead as the start of the third period." Jim Benton
"... is hitting .322 with two home runs an 22 RBI .." Tracy Ringolsby
We have to admit we were amused by this one
"Others (referring to Avalanche fans watching game 3 on TV at the Pepsi Center) were more inclined to sip beer and devour nachos, pretzels and the wurst that the Pepsi Center concession stands could offer." James B. Meadow
June 1, 2001 Denver Post
"It's difficult to follow what Bonds has done the past two weeks and not go ga-ga about the possibilities." (Oh, please. ed.) Mike "The hack" Klis
May 31, 2001 Denver Post
"They haven't see our fans yet." Attributed to Larry Robinson, Coach of the New Jersey Devils
"Now he watching from from the New Jersey Bench." Under "Avs inside"
"The problem with solo homers, though, is no one is on base." (DUH! ed.) By Mike Klis


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Whenever we take on a client, one of the first questions they always ask is, "I want a custom website, but do I need a CMS?".
Many times, when it comes to web design and development, my clients don't even know what a CMS is, or what the point of one is. Which is totally okay – most people don't know what a CMS is (only us developers do! ;).
So, let's take the guess work out of it.
"What exactly is a CMS?"
Content Management System (CMS)
A content management system allows you to do exactly that – manage the existing content on your website. This works perfectly for clients who need to update their website frequently. In fact, that's one of the many questions I have when on-boarding new clients, when it comes to our process. Some examples of this may be e-commerce websites (product updates, pricing updates), blog-heavy websites (weekly / monthly updates to the company blog), and even news-based websites. Any sort of website that needs to be updated with fresh, unique content on a consistent basis (Google loves this, by the way!), generally needs an easy-to-use content management system.
The other great thing about popular CMS' (the big ones being WordPress, Drupal and Joomla), is that these content management systems come with a plethora of amazing, well-supported and fluidly-built plugins. Plugins, in a nut-shell, essentially add whatever functionality you'd like to your website that you can dream up. Some of these plugins are free, some of these plugins are paid. As a developer, we can't tell you how many times we've used plugins on clients sites, generally due to the fact that they're extremely easy (most of the time!) to set up, configure, test and eventually integrate within a website.
Let's quickly go over the pros and cons of having a CMS as your website:
- Ability to add, change and delete the content of your existing website.
- If you have more than one person accessing the website, you can create multiple accounts with multiple roles and restrictions as to what certain people can and cannot edit on the website
- Content can be updated extremely quickly – turnaround time for your website, in terms of maintenance, is generally much faster with a CMS
- Basic website modules such as header navigation, sidebars, and general content are updatable at your fingertips
- Most CMS are actually preferred by search engines – in a nutshell, this means it's much easier to rank high in Google for your industry if you use a content management system
- Security. All CMS' are vulnerable to hackers – however, as long as your site is secure, you shouldn't have any issues.
- Some pages where you have the ability to update your site, input content in a manner of WYSIWYG (What You See Is What You Get) – on inner pages especially (excluding the home page), you have less control of how the content is laid out on a page
- Functionality limitations – although you can use plugins to add value to your site in terms of functionality, a CMS cannot do everything you need it to do
So, we've covered the utmost basics of what a content management system is. What about a custom website?
"When you say a 'custom website'… What do you mean?"
Custom Website
A custom website is a website that's designed and built with custom code, tailored to your needs, based on the project goals that we've set up in our initial meeting. This website is not built on a content management system – it's built using custom, semantic code.
Most companies that request custom designed and developed websites are those who simply do not have enough time to manage a website thereafter it's launched, and would rather the web developer simply take care of updates. Or, maybe they simply do not care to learn how to use a content management system – thus leaving it in the hands of the developer to maintain, once again.
Let's quickly go over the pros and cons of having a custom website:
- There are no limitations when it comes to design and development. It will look, feel and function any way that you can dream up.
- The custom design will reflect your branding
- Generally it's much faster than a CMS
- You don't have to worry about maintenance, as the web developer would do it for you
- It can be pricey, especially if a web developer needs to maintain the site for you after the fact
- Changes may take time – instead of completing the changes at your finger tips, you may have to wait some time for the changes to be completed by the developer
You may be asking yourself at this point, "what's the best option for my company?"
The answer? It depends.
It all depends on your company and personal goals, and of course your budget. You can also combine these two options – a custom designed content management system. This may be on the more pricier side, but in the long run the value it offers is second to none. A platform that you can easily update, that's custom designed to your brand.
Sounds great, doesn't it?


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Growth factors
As discussed else where it is the unique and synergistic balance of many nutrients and co-factors that make up a truly natural anabolic formula. There is no one element that works alone and there is also potential for elements that may appear inactive in isolation to be critical factors when other co-factors are present.
Known growth factors such as creatine are widely understood and excepted and the effect of glutamine and agrinine discussed below, when brought together in an environment where nutrient absorption is optimised and nutrient synergy is present the Growth factor is maximized.
- Growth factors such as:
- Arginine & Glutamine
- Methoxyflavone and Beta ecdysterone
Arginine and Glutamine
As far as supplementation before exercise is concerned, it has been shown that ingestion of 1.5g of arginine will increase human growth hormone (hGH) secretion by blocking release of the hGH-inhibitor somatostatin, although some studies have suggested this causes gastric disturbance. However, 2g of glutamine will lead to elevation of human growth hormone (hGH) 90 minutes later without side effects. It may also be a good idea to ingest some amino acids after exercise, as this has been shown to enhance human growth hormone (hGH) secretion too.
Growth hormone and IGF Research 8(suppl B): 127-9, 1998
Journal of Clinical Endocrinology and Metabolism, 76(6): 1418-22, 1993
Metabolism 48(9): 1152-6
European Journal of Endocrinology, 45(4): 445-50, 2001
American Journal of Physiology; Regulative and Integrative Comparative Physiology 279(4):R1455-66, 2000
American Journal of Clinical Nutrition, 61: 1058-1061, 1995
Medicine and Science in Sports and Exercise, 31(12): 1748-54, 1999
Journal of Endocrinology and Metabolism, 75: 157-162, 1992
Journal of Applied Physiology, 83(5): 1756-1761, 1997
European Journal of Applied Physiology, 72: 460-467, 1996
Methoxyflavone and Beta ecdysterone
Whilst there is a lot of controversy with regard to these two elements we have found that used in a synerstic balance they offer only positive enhancement and work particularly well with in this product to enhance and optimise the anabolic environment naturally.
It is no doubt that some of the benefits and claims for these ingredients have been over hyped and had some outrageous claims associated with them such as "so powerful it's guaranteed to help you pack on up to 10 pounds of rock-hard mass in just 30 days!". One study very good study by International Society of Sports Nutrition found 'we conclude that supplementation of methoxyisoflavone, ecdysterone, and/or sulfo-polysaccharides (CSP3) do not have any affect on training adaptations and/or anabolic/catabolic status in resistance-trained subjects'. http://www.jissn.com/content/3/2/19.
Yet many informed performance specialist and individuals report many positive effects when methoxyflavone and betaecdysterone with in their nutritional regimes. In fact in the trial development of Anabolic Egg with in a small trial group the effects were felt to be positive for increased lean mass whether this came from anabolic properties or positive interaction with the unique proteins and polysaccharides with in the blend a nitrogen positive balance was obtained or improved tendon strength. The overall feeling was one of positive improvement. As there are no negative with regard to the inclusion of such a synergistic stack of ingredients we felt that the inclusion was highly positive. In the presence of a highly bio-available protein and an otimised hormonal state it would appear that these sleeping factors become active participants in a regime for increased muscle mass.
Below are a collection of perspectives and research on these now mythical ingredients.
What is Beta Ecdysterone?
Beta-ecdysterone (ecdysterone, or, 20-Hydroxyecdysone) is a type of ecosteroid, a naturally occurring steroid like compound. Over a 150 ecdysteroids have been identified in many plants and insects. Most commercial ecdysteroids come from plants such as Leuzea carthamoides. Some studies suggest that that Beta-ecdysterone is a powerful anabolic agent, that may enhance protein synthesis and thereby increase lean muscle mass.
Why consider Beta Ecdysterone? Beta-ecdysterone may be of benefit to people looking to increase lean muscle mass.
Summary of Beta Ecdysterone's Phyiological Effects:
- Appears to have an anabolic effect when taken at a dose of around 5mg per kg (i.e. 350mg for a 70kg man)
- May enhance weight loss and muscle size
- Appears to control blood sugar levels
- Appears to act as an antioxidant
Beta Ecdysterone Research research by Russian researchers Syrov and Kurmukov (1976) found that ecdysterone showed anabolic activity and increased protein synthesis. Animal studies in both rats and Japanese quail have demonstrated significant anabolic effects (Slama et al., 1996; Dinan, 2001). Ecdysterone is also believed to have an anabolic effect in humans (Chermynkh et al., 1988; Simakin et al., 1988; Bizec et al., 2002; Chen et al., 2005).
A Russian research study (Chermynkh et al., 1988) compared the muscle building activities of methandrostenolone, a powerful anabolic steroid, and ecdysterone. They demonstrated that ecdysterone had a wider anabolic action on contractile proteins of the muscle than methandrostenolone.
That year another group of Russian of researchers (Simakin et al., 1998) looked at the combined effects of ecdysterone and a high protein diet. They found that when athletes combined a high protein diet with ecdysterone, lean muscle mass increased by 6-7% and body-fat decreased by 10%.
Research also found that ecdysterone can assit to lower blood glucose levels without altering insulin levels (Yoshida et al., 1971; Chen et al., 2005). One recent study ecdysterone lowered blood sugar levels when they were in the normal (5.5mmol/l) and moderate range (11.1-16.7mmol/l) but not when it was in the high range (22.2mmol/l). Therefore, it could be of benefit in the treatment of type-II diabetes, and may aid weight loss.
Despite these positive findings by Russian researchers, there has been no research, performed outside of Russia, that looks at the effects of ecdysterone on human performance. Therefore, ecdysterone cannot be confirmed as an effective anabolic agent, in humans, until further research is performed, in a well-controlled trial and on a large scale, that is widely available for review purposes.
Bizec, B. L., Antigna, J-P., Monteau, F. and Andre, F. (2002) Ecdysteroids: one potential new anabolic family in breeding animals. Analytica Cimica Acta. 473, 89-97.
Chermynkh, N. S., Shimanovskii, N. L., Shutko, G. V. and Syrov, V. N. (1988) The action of methandrostenolone and ecdysterone on the physical endurance of animals and on protein metabolism in the skeletal muscles. Farmakologia I Toksikogia. 51 (6), 57-60.
Chen, Q., Xia, Y., and Qui, Z. (2005) Effect of ecdysterone on glucose metabolism in Vitro. Life Sciences. Article In Press.
Dinan, L (2001) Phytoecdysteroids: biological aspects. Phytochemistry. 57 (3), 325-39.
Konovolova, N. P., Mitrokhin, I. And Volkova, L. M. (2002) Ecdysterone modulates antitomour activity of cytostatics and biosynthesis of macromolecules in tumour-bearing animals. Izvestiya Akademic Nauk, Seriya Bilogicheskaya. 6, 650-658.
Kuzmenko, A. I., Morozova, R. P. and Nikolenko, I. A. (1997) Effects of vitamin D3 and ecdysterone on free-radical lipid peroxidation. Biochemistry (Mosc). 62 (6), 609-612.
Kuz'menko, A. I. (1999) Also a very strong adaptogen and antioxidant: antioxidant effect of 20-hydroxyecdysone in a model system. Ukranskii Biokhimicheskii Zhumal. 71 (3), 35-38.
Simakin, S. Yu. et al., (1998) The combined use of ecdisten and the product 'Bodrost' during training in cyclical types of sports. Scientific Sports Bulletin. No 2.
Slama, K., Koudela, K., tenora, J. and Mathova, A. (1996) Insect hormones in vertebrates: anabolic effects of 20-hydroxyecdysone in Japanese quail. Experientia 52 (7), 702-706.
Syrov, V. N. and Kurmukov, A. G. (1976) Anabolic activity of phytoecdyserone-ecdysterone isolated from Rhaponticum carthamoides. Farmakologia I Toksikogia. 39 (6), 690-693.
Yoshida, T., Otaka, T., Uchiyama, M. and Ogawa, S. (1971) Effect of ecdysteone on hyperglycemia in experimental animals. Biochemical Pharmacology. 20, 3263-3268.
Isoflavone (Methoxyflavone is 5-methyl-7-methoxyisoflavone) is a phytoestrogen that has weak estrogenic activity. Theoretically, some phytoestrogens may inhibit the aromatase enzyme and thus decrease estrogen formation from testosterone and androstenedione. Because they possible act as inhibitors of estrogen by competitively binding to the estrogen receptors, they may increase testosterone production in much the same way as the anti-estrogens (such as clomiphene – Clomid and anastrazole - Arimidex) Decreasing the inhibitory effects of estrogen on GnRH and LH (resulting in LH driven increased testicular steroidogenesis and subsequently increased testosterone production). [1]
A number of animal studies and studies on postmenopausal women have shown, that while the various phytoestrogens vary somewhat in their properties in general they have a suppressing effect on the HTP axis and the result is decreased levels of both total bioavailable testosterone. Isoflavones (such as Methoxyflavone) are poor inhibitors of aromatase than flavones such as chrysin. [2]
Phytoestrogens, may have specific health benefits, [3] and may act to control endogenous sex hormone levels in both men and women, [4] are generally not productive for athletes wishing to increase muscle mass and strength.
But as already mentioned, some bioflavonoids (a loose term that includes isoflavones, anthocyanins, flavans, favonols, flavones, flavanones hesperidin, rutin, and citrus bioflavonoids), however may be very useful under certain circumstances. One study found quercetin and fisetin, two naturally occurring bioflavonoids were shown to mobilize lipids and enzymes in the absence or presence of epinephrine in intact rat adipocytes [5]. Results of this study suggest that some flavonoids act synergistically with epinephrine on beta-adrenergic receptors to stimulate adipocyte lipolysis. Thus these bioflavonoids may be especially useful in the high fat, high protein, low carbohydrate anabolic diet.
[1] Kuiper GGJM, Lemmen JG, Carlsson B, et al. 1998 Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology. 139:4252-4263.
[2] McGarvey C, Cates PA, Brooks A, Swanson IA, Milligan SR, Coen CW, O'Byrne KT. Phytoestrogens and gonadotropin-releasing hormone pulse generator activity and pituitary luteinizing hormone release in the rat. Endocrinology 2001 Mar;142(3):1202-8.
[3] Tham DM, Gardner CD, Haskell WL. 1998 Potential health benefits of dietary phytoestrogens-a review of the clinical epidemiological and mechanistic evidence. J Clin Endocrinol Metab. 83:2223-2235.
[4] Sudhir K, Komesaroff PA. Cardiovascular Actions of Estrogens in Men Journal of Clinical Endocrinology and Metabolism Volume 84, Number 10. October 1, 1999.
[5] Kuppusamy UR. Das NP. Potentiation of beta-adrenoceptor agonist-mediated lipolysis by quercetin and fisetin in isolated rat adipocytes. Biochemical Pharmacology. 47(3):521-9, 1994 Feb 9.
[6] Formica JV, Regelson W. Review of the biology of Quercetin and related bioflavonoids. Food Chem Toxicol 1995;33:1061-1080.
[7] Lamson DW, Brignall MS. Antioxidants and Cancer III: Quercetin. Altern Med Rev 2000 Jun; 5(3):196-208."
Ipriflavone / Methoxyflavone
So what about Ipriflavone and/or 5-methyl-7-methoxy-isoflavone? What are the claims? What is the mechanism of action?
Most people familiar with Ipriflavone know that it has been extensively studied with respect to bone metabolism, or more specifically, osteoporosis. For instance, one representative animal study found ipriflavone inhibited parathyroid hormone-, vitamin D-, PGE2-, and interleukin 1 stimulated bone resorption (1). The effects of Ipriflavone on bone loss have also been demonstrated in humans. The same protocol was used throughout most of these studies (i.e. 200 mg ipriflavone or placebo three times daily). Several two-year studies looked at women immediately postmenopause (age 50-65) and found bone mass was maintained or improved slightly in the ipriflavone groups while those in the placebo groups experienced significant bone loss (2,3,4,5).
Ipriflavone acts as an estrogen "sensitizer" in several tissues:
While Ipriflavone does not have any significant direct estrogenic effects, it does enhance the effects of estrogen, particularly in bone, the thyroid gland, and the gastrointestinal tract (6,7). In bone, ipriflavone makes estrogen's bone sparing effect more potent. Ipriflavone, like the soy flavone genistein, has decent affinity for the estrogen receptor-beta (8).
Ipriflavone's effects on Ca2+:
In the heart, ipriflavone has been shown to prevent Ca2+ ions from building up in the mitochondria (9). Ca2+ builds up in mitochondria when there is insufficient oxygen. Ipriflavone actually enables heart muscle tissue to survive longer without oxygen. This means less damage due to hypoxia (lack of oxygen). No studies have been performed looking at skeletal muscle function during ipriflavone supplementation however, it is not unreasonable to assume a similar function in skeletal muscle. More research is needed in this area.
"Test of anabolic effect: The investigation was carried out with castrated rats by means of the musculus levator ani test and vesicula seminalis test. The preparations were administered orally for a period of three weeks. The tests were performed by the method of Eisenberg and Gordan (Eisenberg, E., Gordan, G. S. J.: J. Pharmacol. 99, 38, 1950). In addition to that, also the weight of the prepared diaphragm of the animals was established. According to these tests, the weight of musculus levator ani rose by a Student significance of p 0.01, the weight of vesicula seminalis did not increase while the weight of the prepared diaphragm of the animals increased by a Student significance of p 0.05. On the basis of these results the preparations proved to possess the anabolic activity free from androgen effect".
The patent goes on to relate:
"The weight yield increasing effect induced by doses of 2 g/100 kg of feed was in the various animal species as follows:
- 8 to 15% in calves
- 7 to 10% in cattle
- 7 to 10% in hogs
- 8 to 20% in poultry
- 10 to 20% in rabbits
- 8 to 12% in guinea pigs"
The amount of feed given to these animals did not increase, only their body weights increased. They did test their new compound on ill humans as well:
"The anabolic effect of the composition was tested on thinned (asthenic), reconvalescent, dystrophic patients suffering from pathological thinness. It has been found that as a result of a treatment lasting for some weeks the patients have gained 2-3 kg of weight. According to our experiments the physical condition of the patients has also improved."
In the patent on 5-methyl-7-methoxy-isoflavone (U.S. patent 4,163,746), the details on increasing ipriflavone's effectiveness are outlined. Several compounds are mentioned, namely 5-methyl-7-methoxy-isoflavone; 5-methyl-7-ethoxy-isoflavone; 5-methyl-7-(2-hydroxy-ethoxy)-isoflavone; and 5-methyl-7-isopropoxy-isoflavone. The same guys filed the 5-methyl-7-methoxy-isoflavone patent some 3 years after they filed the ipriflavone patent. Basically, all this patent does is show that when you methylate the isoflavone, you make it nearly twice as anabolic compared to ipriflavone. The claims are the same except that I noticed the claim that the "compounds are useful as anorexigenic agents. A significant advantage of these compounds over known catabolic agents is that they do not exhibit a central stimulating effect." Now this is quite a claim to add to the fact that they profess that it is an anabolic, as well. So not only does it cause a shift towards more muscle, it also decreases appetite at the same time. Thus far, no manufacturers that I have seen make the claim that ipriflavone or 5-mthyl-7-methoxy-isoflavone is a good appetite suppressants. But if they wanted to I guess they could, based on this patent.
In conclusion we do feel that ipriflavone/methoxyflavone is a valuable supplement to anybody who trains regularly. It "should" help to strengthen bones and tendons and even enhance cellular metabolism. If the patents are true, it may even increase muscle mass and decrease fat mass if used long enough. Keep in mind that we only answered the first question completely. There is still NO good explanation of how ipriflavone or its methylated derivatives could produce non-hormonal, or hormonal for that matter, anabolic effects.
1. Tsutsumi N, Kawashima K, Nagata H, et al. Effects of KCA-098 on bone metabolism: comparison with those of ipriflavone. Jpn J Pharmacol 1994;65:343-349.
2. Adami S, Bufalino L, Cervetti R, et al. Ipriflavone prevents radial bone loss in postmenopausal women with low bone mass over 2 years. Osteoporos Int 1997;7:119-125.
3. Gennari C, Adami S, Agnusdei D, et al. Effect of chronic treatment with ipriflavone in postmenopausal women with low bone mass. Calcif Tissue Int 1997;61:S19-S22.
4. Agnusdei D, Crepaldi G, Isaia G, et al. A double blind, placebo-controlled trial of ipriflavone for prevention of postmenopausal spinal bone loss. Calcif Tissue Int 1997;61:142-147.
5. Valente M, Bufalino L, Castiglione GN, et al. Effects of 1-year treatment with ipriflavone on bone in postmenopausal women with low bone mass. Calcif Tissue Int 1994;54:377-380.
6. Effect of ipriflavone on the response of uterus and thyroid to estrogen. Life Sci 1986 Feb 24;38(8):757-764.
7. Yamazaki I, Kinoshita M. Calcitonin secreting property of ipriflavone in the presence of estrogen. Life Sci 1986;38:1535-1541.
8. Arjmandi BH, Khalil DA, Hollis BW. Ipriflavone, a synthetic phytoestrogen, enhances intestinal calcium transport In vitro. Calcif Tissue Int. 2000 Sep;67(3):225-9.
9. Feuer L, Barath P, Strauss I, Kekes E. Experimental studies on the cardiological effects of ipriflavone on the isolated rabbit heart and in rat and dog. Arzneimittelforschung 1981;31(6):953-8 www.mesomorphosis.com/supplement-profiles/ipriflavone-methoxyflavone.htm


text: Dartmoor Xplorations This section contains stories of days and walks I have made and spent on Dartmoor, many of which were in pursuit of content for this website. As well as describing the factual details of the walks I have included the various experiences encountered on them. Autumn ColoursBelleverBelstone CommonBlack DunghillBlackall's DriveBurratorConies DownDart ValleyDartmoor 365 XplorationDartmoor Circular 1887Dartmoor ReminiscingDartmoor Xmas 2017Dartmoor's July JauntDevonport LeatDunnabridgeFingle WoodsHameldown RidgeHaytor DownHolne and BackLydford GorgeMidwinter Dartmoor 1886Mistery TourMists of TimePeregrinating BelleverPew Tor PilgrimagePostbox WalkRain or ShineSatan & the CrossSnowdon StrollSousson's StrollStat's House StrollStep Back in TimeTavistock and BackTavy TrundleThe Buckland DrivesThree Stone CirclesTo The SpinstersTop Tor to Buckland BeaconVisitors' BookWindy Post 2016-04-07 +Tim Sandles Share Facebook Twitter Google + Stumbleupon LinkedIn Pinterest


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Grantham House
Location: 33 Rodd Street, Canowindra NSW 2804 Australia
We are conveniently located, and our rooms feature beautiful décor! We are able to accommodate you in either of our two queen rooms or our twin room. At Grantham House we are more than just a Bed & Breakfast - as a guest you will enjoy the lovely sitting room with the open fire, breakfast room and stunning dining room. We also have a fabulous BBQ area and verandahs surrounding the house that are solely for your use while you enjoy your stay.
Grantham House in Canowindra is the perfect accommodation for a sublime getaway.
Web: Visit website
Phone: 0419 010 564


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- Click the Create Flow icon associated with finding a distinct simple user.
The API Orchestration user interface is displayed.
- Select and pull the simpleusers node onto the flow editor from the Models list. Note that the Start node is automatically connected to the input of the simpleusers node.
- Name the node: Find a distinct user
- Select the
- Select Parameters.
- Enable all parameters and configure them according to the
distinctparameters in listed in . If the Selector parameter type is selected from the Selector drop-down menu, as you begin typing in the parameter field, a drop-down menu of valid parameter configuration options will be displayed. You may select a configuration from the listed options or continue typing to manually enter a parameter configuration. For additional information on the Model node and General node configuration parameters, refer to Flow Orchestration.
- Select Outputs.
- Configure the next output per the
distinctoutputs listed in Flow Orchestration.
- Select and pull an HTTP node onto the flow editor from the Core list.
- Name the node: Find succeeded
- Select Parameters.
- For the status parameter, select Number and enter 200 in the field.
- Enable the body parameter, select Selector, and enter
$.modelsin the field.
- Leave the headers parameter disabled.
- Connect the next output of the Find a distinct user node to the input of the Find succeeded node. For additional information on connecting nodes in a flow, refer to Manage Nodes. The completed flow is displayed.
- Click Save.
- On the next screen, click Proceed. The server will be restarted and the Find a distinct user flow will be saved and enabled.


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Do you want to talk to God? Then talk! Do you want to hear God's word? Then LISTEN! God loves you DEARLY! You don't need to go to a building with a cross upon its door to listen to a man on a stage who has been appointed by another man to a title that declares him to be closer to God than you! Is that the way to hear God's Word? That is man's word. No one is any closer to God than you! Every being in Creator's universe are ALL EQUAL, including you! You have always been told that this is the only way to hear God's word. They told you that you were a sinner, unworthy of direct contact with God. God is the Creator who created all things! And God created YOU!
Does it make sense that we constantly talk AT God (ie. praying) and then NEVER listen to his response? Does this one-way conversation make sense to you? Do you believe that God has far more wisdom than us? Do you believe that it is wise, then, to listen to what God has to share with us? Otherwise, we are like young children who chatter incessantly at their parents while busy DOing what they DO without stopping long enough to listen to the response of their parents. "Mommy, can I have this? Daddy, can I have that? I have a boo-boo, make it better! Why is this so? Why is that so? Why? Why? Why?" It is time to graduate from being young children and begin to talk WITH our parents instead of AT them. It is time to LISTEN to God!
So listen to your heart! Listen to the silence, in the silent moments is when you can hear your Creator whispering in your ear! God's word is in the breeze, it is in the trees and the chirping birds and it is in your hearts! Sometimes the answers are in the lyrics of a song when you turn on the radio, or the words of a stranger on the elevator, or a symbol on a sign that catches your eye while driving. When we don't stop to listen, God tries to reach us in other ways. We have to learn to LISTEN in all the ways that heaven reaches out to us.
The best way to listen is to learn some basic meditation techniques. The main purpose of meditation is to learn to quieten the constant chatter that goes on in the human brain. Try it! For ten seconds, try to think of nothing, absolutely nothing. Really, go ahead! If you could do that on your first try, CONGRATULATIONS! Not many people can. Practice on your own or go online and find some guided mediations. Soon you will find some silent moments. With practice, the silent moments get longer. In the silent moments, heaven's words and images will speak to you. Does this sound like too much work? Is hearing the word of God not worth it? God is speaking to you. It is time to start listening!
Praying is talking to God. Meditating is listening to God!


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At the start of the encore, Ed thanks the Buzzcocks and talks about watching a video where a band was pretending to be a punk band and he thanks the "real thing," the Buzzcocks. "Buzzcocks were opening for the Sex Pistols before I was fondling my first erection," and he talks of how he met them a long time ago when he was a crew guy carrying their gear. "You never know how things will turn out."
Set: Can't Keep, Daughter, 1/2 Full, Go, Save You, Ghost, Better Man, Grievance, Evacuation, Even Flow, In Hiding, Cropduster, Corduroy, Elderly Woman, Red Mosquito, improv, Rearviewmirror
Encore 1: Given To Fly, Wishlist, Not For You/(Start Me Up), Footsteps, Do The Evolution, Jeremy
Encore 2: Fuckin' Up
Encore 3: Yellow Ledbetter
Thursday, February 19, 2009
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U.S. Relations With Brazil
More information about Brazil is available on the Brazil Page and from other Department of State publications and other sources listed at the end of this fact sheet.
The United States and Brazil traditionally have enjoyed robust political and economic relations. The United States was the first country to recognize Brazil's independence in 1822. As the two largest democracies and economies in the Western Hemisphere, the United States and Brazil have a partnership that is rooted in a shared commitment to expand inclusive economic growth and prosperity, promote international peace and security and respect for human rights, and strengthen defense and security cooperation.
The United States and Brazil have a long history of deepening people-to-people ties through exchanges in education, energy, health, agriculture, science and technology, and innovation. Education cooperation continues to thrive with numerous initiatives for youth, educators, and professionals. For example, the bi-national Fulbright Commission, established in 1957, has supported study and research exchanges for thousands of scholars between the two countries. Education USA helps Brazilian university students access information and opportunities for study in the United States at its 34 centers throughout the country. The government of Brazil continues to invest in Post-initiated exchange programs such as the Professional Development of Public School English Language Teachers (PDPI) in the United States, and a considerable expansion in Brazil of the English Teaching Assistant Program. The two countries have extensive scientific exchanges at the individual researcher level, as well as bilateral collaborations with the U.S. Geological Survey, NASA, the Environmental Protection Agency, and the National Institute of Standards and Technology. The two nations collaborate in weather monitoring, metrology and standards, environmental impact monitoring, an extensive range of public health efforts, and Brazil is home to the U.S. National Institute of Health's (NIH) largest research portfolio in Latin America.
The United States and Brazil are working together on key global, multilateral, and regional issues. Brazilian space agency AEB is a member of NASA's GLOBE science program, with 119 Brazilian schools participating in projects such as the GLOBE Mosquito Habitat Mapper (MHM) app that connects to the GLOBE database to help track mosquitoes that spread Zika and other diseases. The United States and Brazil are also advancing human rights issues in bilateral and multilateral fora. In addition to efforts to fight racial and ethnic discrimination, advance gender equality, and combat exploitative child and forced labor, the United States works with Brazil at the United Nations Human Rights Council to support the rights of lesbian, gay, bisexual, transgender, and intersex (LGBTI) persons, and to defend freedom of expression and advocate for people with disabilities. The United States and Brazil are both committed to strengthening the multi-stakeholder approach to internet governance to preserve the benefits of an open, interoperable, secure, and reliable internet. The Department of Commerce co-hosted the first ever U.S.-Brazil Digital Economy Summit with the Federation of Industries of the State of São Paulo (FIESP) in October 2017. To promote the implementation of the Post-2015 Development Agenda Sustainable Development Goals, the United States and Brazil are collaborating on sustainable agriculture, food security, and nutrition.
The United States and Brazil are strengthening cooperation on defense issues, including research and development, technology security, and the acquisition and development of products and services. These agreements promote joint exercises and facilitate the sharing of sophisticated capabilities and technologies. In September 2016, U.S. and Brazilian officials inaugurated a bilateral Defense Industry Dialogue, designed to improve coordination with the private sector and facilitate trade in the defense industry. The Dialogue met again in Washington in October 2017. In addition, Brazil and the United States restarted their longstanding Disarmament and Nonproliferation Dialogue and Political Military Dialogue in September and October 2017, and signed a Master Information Exchange Agreement in March 2017 to facilitate research and development.
U.S.-Brazil Bilateral Economic Relations
Brazil is the world's ninth-largest economy and the United States is Brazil's second-largest trading partner. Two-way trade was $88.2 billion in 2016. The United States had a $22.3 billion trade surplus with Brazil in 2016. Brazil's main imports from the United States are aircraft, machinery, petroleum products, electronics, and optical and medical instruments. The United States is Brazil's second-largest export market. The primary products are crude oil, aircraft, iron and steel, and machinery. According to the U.S. Bureau of Economic Analysis, the United States had invested $64.4 billion in Brazil as of 2016, while Brazil had invested $36.9 billion in the United States. Brazilian investment in the United States supports more than 74,200 jobs.
The United States welcomed more than 1.7 million visitors from Brazil in 2016, comprising the eighth-largest group of visitors. There were approximately 570,000 U.S. visitors to Brazil in 2016, comprising the second-largest source of visitors to Brazil. Travel industry experts expect the introduction of a less expensive electronic visa option for American citizen travelers to Brazil to boost tourism in 2018 and beyond.
Bilateral exchanges to promote economic relations between the United States and Brazil are strong. The United States and Brazil conduct regular exchanges on trade facilitation, regulatory good practices, and standards. The 16th plenary of the Commercial Dialogue occurred in May 2017, but regular exchanges at the work level continued throughout the year.
In January 2016, the United States Patent and Trademark Office and Brazil's patent and trademark agency, INPI, launched the "Patent Prosecution Highway" (PPH) program, a fast-track examination agreement that allows the patent offices to leverage each other's work product, and is a tool that will help improve patent quality and reduce Brazil's backlog.
The two countries have also increased exchanges in global best practices in infrastructure development. The second meeting of the U.S.-Brazil Infrastructure Memorandum of Cooperation (MOC) Working Group on Infrastructure Development took place in December 2017 in Brasilia, and coincided with the signing of a Global Procurement Initiative (GPI) to exchange best practices in government procurement.
U.S. Assistance to Brazil
The U.S. Agency for International Development (USAID) and Brazil are working together to promote development in other countries, particularly in Africa and Latin America. USAID and Brazil have trilateral food security programs to increase agricultural productivity and address school nutrition in Honduras and Mozambique, and are teaming up to address the Fall Armyworm outbreak across Sub-Saharan Africa. USAID partners with four Brazilian ministries and the private sector to improve biodiversity conservation in the Amazon, primarily through close bilateral cooperation on strengthening Brazil's vast Protected Areas system, including indigenous territorial management. Through public-private partnerships, USAID supports projects focused on biodiversity conservation, science, and technology, as well as entrepreneurship and access to English language training for Brazilian youth, while increasing the impact of social investments made by U.S. companies in Brazil through their corporate social investment programs.
Brazil's Membership in International Organizations
Brazil and the United States belong to a number of the same international organizations, including the United Nations, Organization of American States, Inter-American Development Bank, G-20, International Monetary Fund, World Bank, and World Trade Organization. Brazil traditionally has been a leader in the inter-American community, and is a member of the sub-regional MERCOSUR and UNASUR groups.
Bilateral Representation
Principal U.S. embassy officials are listed in the Department's Key Officers List.
Brazil maintains an embassy in the United States at 3006 Massachusetts Avenue NW, Washington, DC 20008 (tel. 202-238-2700).
More information about Brazil is available from the Department of State and other sources, some of which are listed here:
Department of State Brazil Page
Department of State Key Officers List
CIA World Factbook Brazil Page
U.S. Embassy
USAID Brazil Page
HHS Office of Global Affairs Page
CDC Brazil Page
History of U.S. Relations With Brazil
Human Rights Reports
International Religious Freedom Reports
Trafficking in Persons Reports
Narcotics Control Reports
Investment Climate Statements
Office of the U.S. Trade Representative Countries Page
U.S. Census Bureau Foreign Trade Statistics
Export.gov International Offices Page
Library of Congress Country Studies
Travel Information


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Search Hotels
Club Quarters Gracechurch
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If you intend to pay by cash, Club Quarters will require a security deposit at check-in. Guests under the age of 18 years must be accompanied by a parent or an official guardian. Limited restaurant, bar and room service is available over the weekend. No children's menus are available. Using the contact details found on your booking confirmation, you can contact the hotel to find out more about parking. An extra bed for the one-bedroom suite is available upon request and subject to availability. Read More
Club Quarters are new, private, full service hotels designed primarily for business travelers. They are exclusive and club-like, with entry restricted to guests.
|Nightly rate
|£107.78 per room
Venue Details & Map
Club Quarters Gracechurch
- Address
7 Gracechurch StreetSpitalfieldsLondonEC3V 0DR
- Telephone:
- +44 (0)20 7666 1616
- Room Facilities
- Air conditioning
- Self Catering Facilities
- Cooking facilities
- Linen provided
- Microwave


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We are planning on leaving Lucaya today headed for Hoffman's Cay in the Berrys. Weather has been less than perfect for another long passage but tonight looks ok. It is about 75 miles over open ocean into the wind but the wind should be light enough for a safe passage. Maybe not a comfortable passage, but a safe one.
There won't be internet in the Berrys because where we are going doesn't have any development on shore. It has cliff jumping and blue holes but no internet. Follow us on SPOT until we get to Nassau in a week probably.


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The Squash Blossom in Vail Village now features San Francisco jewelry designer Rebecca Overmann.
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Welcome to the final part of the Euro trip series! After Switzerland, our next destination was this gorgeous little town called Innsbruck in Austria. Sadly, I got only one day to spend here but from what I saw, I'm definitely going back to explore more. Our first stop was in Wattens where we visited the
Tag: Euro trip
Euro Trip – Part II
I'm back with the second edition of my Europe blog and this time, I'll be taking you around the mesmerizing Swiss Alps. So, let's goooo! From Paris, we drove for 700 kilometers to our next destination which was surrounded by Swiss Alps. The small town of Engelberg is as beautiful as its lush green mountains
Euro Trip – Part I
If you have been following on social media, you know I went for a short yet beautiful tour of Europe in July. After planning and delaying it for long, here am I with my travelogue, sharing my experience from the beautiful Paris. Hope you guys enjoy it! We took a flight from Delhi to Paris


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I spent an afternoon and $65 at the post office yesterday sending love out there into the world. Really it's all just a desperate plea for mail. My maillady has been dissing me hard lately. It was a packaging frenzy here over the weekend. I was only able to get to it in distracted fits and spurts, so if you get your package and the stickers don't match the card inside, or your note is addressed to someone else please forgive me! Hopefully I got everything straight. Oh, and pay no attention to the 'what's this worth' part of the customs forms. I can't even remember what's in the packages by the time I get to the post office and I just throw out numbers willy nilly. The willy nilly queen of hair brained ideas. That's me! And now I've got my formerly clean, organized craft room all gummed up with vintage again. I found some more cool things. Maybe next week some more swappers?
6 thoughts on "love me internet!"
hannah says:
fabulous, count me in! cant wait to get my package!
ps. does oscar have the NO! cd by TMBG?
dawn says:
ooooh, more swaps! I have a little pile of goodies sitting beside my computer, fabrics, buttons and trims. But I won't divulge anymore details…
hillary says:
hannah, yep we have no
dawn, can't wait! tuesdays are an excellent day to go to the post office 😉
valentina says:
Hi! I need to stop lurking! I'd love to participate. It all went so quickly this time around. I'll be glued to my screen on Tuesday.
hillary says:
oops, sorry valentina, I'm being very vague these days. I was just hinting to dawn that today would be a good day for her to mail me those enticing treats!
I'm not sure what day I'll be posting new stuff.. have to see how it goes.
thanks 🙂
eireann says:
I love to read your posts here. Such sweet things!


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Gogol's short story The Nose is one of my favourites – not quite as favourite as The Overcoat but a close enough second. I was thinking about it today as I came across this useless fact: Admiral Nelson of Trafalgar Square has a spare nose lodging up the side of Admiralty Arch.
This is what I love about the world. You read something in a story that is completely brilliantly barking mad and then reality turns and says "well, actually…"


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Ska World
Bustamento is a musical ensemble led by Australian musician Nicky Bomba. The band began as an exploration into the styles of early Caribbean music particularly Mento and Calypso music, by a group of musicians who have played together for over 15 years. Bustamento are a seven piece ensemble with drums, guitar, ukulele bass, piano, steel pan, trumpet and saxophone.
Artist's Links
Time2:30 pm - 3:15 pm
LocationMain Stage