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Date(s) - 01/26/2018
6:30 pm - 10:00 pm
House of Blues Anaheim
Tickets are now on sale for the 6th annual She Rocks Awards!
Join us for the
Friday, January 26, 2018
The House of Blues Anaheim, Anaheim CA
6:30pm – 10:00pm
Pat Benatar, Melissa Etheridge, and The B-52s' members Cindy Wilson and Kate Pierson to be honored at the 2018 She Rocks Awards by The Women's International Music Network
Tickets on sale now. This iconic event celebrating women in music takes place January 26, 2018 in Anaheim, CA
The Women's International Music Network (the WiMN) announces that Pat Benatar will be honored at the 6th annual She Rocks Awards on Friday, January 26, 2018, during the NAMM Show in Anaheim, CA.
Four-time GRAMMY® Award winner Pat Benatar first landed on the charts and in homes across America during the early days of MTV in the 1980s. Together with producer, guitarist and songwriting partner, Neil Giraldo and a jaw-dropping, classically-trained voice and fierce determination, they ruled the radio with hits such as "Love Is A Battlefield," "Heartbreaker," "We Live for Love," "We Belong," and the signature "Promises in The Dark." After three decades, the duo has sold over 30 million albums worldwide, cementing their place in rock history. Married for 36 years and musical partners for 38 years, they continue to wow audiences during sold-out concerts. For more info, visit www.benatargiraldo.com.
The WiMN Founder, Laura B. Whitmore, comments, "Pat Benatar's talent and contributions to rock music are an inspiration to women everywhere, whether they are fans or aspiring artists themselves. We are truly honored to recognize her at this year's She Rocks Awards."
Benatar joins a host of 2018 honorees that includes Melissa Etheridge, The B-52s members Cindy Wilson and Kate Pierson, Exene Cervenka of X, Fanny, plus a collection of role models from all walks of the music and audio industries. View the full list of this year's honorees here.
This high-energy evening includes live music, awards and speeches, celebrity appearances, a fabulous silent auction, food with cash bar, amazing gift bags and so much more! A NAMM Show badge is not required to attend the She Rocks Awards.


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What an incredible year I've had, learning from the best (Angela Ward-Brown)! I have shot in all sorts of scenarios like low lighting, rain, harsh sunlight and I have learnt how to tackle these tricky lighting situations, which I can now confidently handle.
It's scary to think I'm out on my own now, but I'm looking forward to starting my journey into my own photography career.
Lainston House is one of my fav locations in Winchester. It reminds me of when I first started out as a photographer, and dragging my poor children along to photograph them in the gardens. Noting beats the autumn colour like Lainston!
Thank you Emily and Alex for letting me be apart of your day and to Angela for patiently training me for a year x

subset: commoncrawl


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- dovewithscalesAsked on March 30, 2017 at 02:54 PM
I wasted all that time and your form isn't accessible. What gives?Page URL:
- JanAnswered on March 30, 2017 at 04:36 PM
Your account is currently suspended. Our phishing tool suspended your account automatically. I checked your form and I can see that you are asking for "account names". However, I can verify that you are not violating our terms of use.
Your account is now activated. Hope that helps. Thank you.


text:
It's never great when somebody is filing for bankruptcy. Use the article that follows as a way to learn how you can avoid bankruptcy.
The professional that helps you file with needs to know both the good and accurate picture of your finances.
Before making the decision to file for bankruptcy, be sure you've weighed other options.For instance, consumer credit counseling services can often help you figure out a workable repayment plan with creditors. You can also talk to creditors and ask them to lower payments, just be sure any debt modifications you agree to are written and that you have a copy.
Be sure you can differentiate between Chapter 7 and Chapter 13 bankruptcy. Chapter 7 is the best option to erase your debt. All of your financial ties to the people you owe money to will go away. Chapter 13 bankruptcy allows for a payment plan that takes 60 months to work with until the debts go away.
Consider if Chapter 13 bankruptcy for your filing. If you are receiving money on a regular basis and your unsecured debt is under $250,000, Chapter 13 may be right for you. This plan normally lasts from three to five years, your unsecured debt will be discharged.Keep in mind that even missing one payment can be enough for your case.
This stress may lead to something worse like depression, especially if you are not making any efforts to adopt a positive attitude. Life is going to get better once you get this situation over with.
In order for this to succeed, your car loan must be one with high interest, you need a solid work history and the car should have been bought 910 days or more prior to you filing.
It is possible to get an auto loan or mortgage during the repayment period for Chapter 13 case remains active.You will have to see your trustee and the approval for this new loan type. You will need to show them why and prove that you can handle paying back the new loan. You will also need to explain why the purchase is necessary.
Know the rights when filing for bankruptcy. Some bill collectors will try to tell you that your debts can't be bankrupted. Only a few kinds of debt, including child support and tax liens, are ineligible for bankruptcy. If you are unsure about specific types of debt, report the collector to the attorney general's office in your state.
Make sure you are acting at an appropriate time. Timing is very important when it comes to personal bankruptcy cases.In some cases, you should file right away, while other situations benefit from trying to get certain finances in better shape before filing. Speak to a bankruptcy lawyer to discuss the ideal timing is for your personal situation.
You do not have to surrender to bankruptcy. Take the information provided here and avoid filing if at all possible. Begin today with what you learned here and soon you will see positive changes in your financial situation, so you can avoid the harmful process of filing for bankruptcy.


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Setting aside Ms. Miers herself and looking at the political fights avoided or put off, I find myself torn.
The pragmatic part of me says "Trust the President" for the reasons I have outlined in previous posts.
The idealistic conservative part of me says "No way should this lady have a chance; let's thrown JRB in there and force the issue" for all the reasons everyone else has pointed out.
Wheels within wheels within wheels, and I'm basically glad I don't have to be the one to decide what to do.
The choices facing the President:
1. Assuming he is truly a step ahead of us, get Miers confirmed with relatively little fuss from the left, knowing that a few decisions will reassure the base and leave room for the Scalia Jr. next time.
2. Knowing the conservatives aren't liking this selection, allow the nomination to stall and fail either in committee or the full Senate vote because of torpedoes from the Elephant side. Nominate Scalia Jr and go for broke.
3. Pull her or convince her to step aside. Nominate someone more to the base's liking and expectation and prepare for the Senate showdown. Must make sure to have second and third nominees in mind and ready to go. One should be Scalia Jr. and the other more moderate but still solidly conservative.
There are various political consequences from each choice, none of them particularly palatable.
I think the worst happens when any nominee is voted down, forcing a new nomination as history shows the second nominee typically is more moderate and pliable to the liberal side. They also tend to be the truly stealth candidates that we should really worry about. Political capital is drained by that point, making other agenda items more difficult to work around, not to mention the time and attention wasted on the first nominee and the rumblings over the second.
Other points I have addressed in recent days deal with the makeup of the Senate and the upcoming '06, '08, '10, and '12 elections. Due to the ages of the various current Justices, the presidents of 2008 and 2012 will have possibly as many as 5 or 6 nominations.
Perhaps it is time to rethink my guarded support for Harriet Miers. As it seems imperative to me to weed the Senate garden and toss out and RINOs, it may be time to think about forcing the issue: Put up Scalia Jr., inform the Spineless Republicans and Red-State Democrats that the mandate has been given -- twice -- and lead. Going into an election year, the conservative base is riled up enough to decide that a faithless (R) or a (D) that wouldn't cross over has had enough time on the public dime and it's time to go home. This base has had it -- borders, spending, etc. The President may have misoverestimated himself on this one. The base wants the fight, they've been waiting for it for far too long, and pressing the issue going into an election year with superior numbers seems natural and logical. And we have been let down by this President in the past due to fear of RINOs and his desire to get along with the Enemy.
The last few days I have argued for trusting the President and assuming that he has made this nomination because he has the personal knowledge that Ms. Miers *is* Scalia Jr. and the Dems won't know that until it's too late. This has been increasingly difficult to do, as the best case the White House can make for Ms. Miers is quite far from convincing, even to someone like myself who wants to believe, and it does not seem to be a tactic to put off the Dems. She seems a fine lady, to be sure. If I needed someone to direct an organization or advise on business law, she'd be on the short list. But Associate Justice? It's getting harder to buy, even when I take her out of it and look at the politics involved in getting the results desired through unorthodox means. She does in fact appear to be a lightweight who has not handled herself well in statements I have read, and there are plenty of pieces of her history that should make any conservative decide to withhold support. The *only* possible reason to support her is because of my original proposition, that Bush knows she's really our originalist and has calculated that only a stealth candidate survives this Senate, saving a fight for later when he has reliable (R) votes. Every other qualification test against her does not measure out well at all.
This President is not a conservative. Much of the Senate Republicans are not conservative. If we are going to get Scalias on the Court we have to have conservatives in the Senate and Presidency. The question is, do we get there by trusting the President now and support Ms. Miers, or do we get there by rolling the dice and jamming Luttig, Rogers, Brown, etc. down the throats of RINOs and Dems alike? We need to figure it out, or the Lizard Queen is going to get choose as many as 6 Justices.
I do not know. I honestly cannot say which approach is correct. Principles are important, but so is getting your nominee in, and she is his nominee.


text: Catriona Kelly works on Russian literature and on Russian cultural history, particularly Russian modernism, gender history, the history of childhood, national identity, and the recent history of Leningrad/St Petersburg. She has published a large number of books and articles in these areas, sponsored by grants from the Leverhulme Trust and the British Academy (see http://www.mod-langs.ox.ac.uk/russian/childhood). From 2007 to 2011, she led a large international project on Russian national identity, sponsored by a major grant from the Arts and Humanities Research Council (see http://www.mod-langs.ox.ac.uk/russian/nationalism). Her study of cultural memory in Leningrad/St Petersburg since 1957, supported by work in archives, interviews, and first-hand observation as well as work with printed sources, St Petersburg: Shadows of the Past, was published by Yale University Press in 2014. Soviet and Post-Soviet Identities, co-edited with Mark Bassin, came out in 2012 from Cambridge University Press. Other interests include oral history (for information about the Oxford Archive of Life History, see http://www.ehrc.ox.ac.uk/lifehistory). Catriona Kelly also works as a literary translator, particularly of poetry, and writes for the general literary press (particularly The Guardian and The Times Literary Supplement). She is on the editorial board of several journals, including Kritika, Slavic Review, Slavonic and East European Review, and Antropologicheskii forum/Forum for Anthropology and Culture (St Petersburg). In 2013, she was pre-elected President of the Association of Slavic" East European, and Eurasian Studies, USA (ASEEES) for 2015. She is the first person not working at a US university to hold this position.


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Chateau Latour 1982 . Pauillac . 1bn, 1ts. Bottle (2). ... (Total: 2 Btls. )Click the image to load the highest resolution version.
DescriptionChateau Latour 1982
1bn, 1ts
Bottle (2)
"...the 1982 Latour has been the most opulent, flamboyant, and precocious of the northern Medocs, especially the St.-Juliens, Pauillacs, and St.-Estephes. It hasn't changed much over the last 10-15 years, revealing sweet tannins as well as extraordinarily decadent, even extravagant levels of fruit, glycerin, and body. It is an amazing wine, and on several occasions, I have actually picked it as a right bank Pomerol because of the lushness and succulence of the cedary, blackberry, black currant fruit. This vintage has always tasted great, even in its youth, and revealed a precociousness that one does not associate with this Chateau. However, the 1982 is still evolving at a glacial pace. The concentration remains remarkable, and the wine is a full-bodied, exuberant, rich, classic Pauillac in its aromatic and flavor profiles." (100 pts. Robert Parker, Wine Advocate #183, June 2009)
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The origin of the place name for -- Mountainville (Sanpete County) -- is summarized in a PDF document. This brief article is extracted from the publication UTAH PLACE NAMES (1990), compiled and written by John W. Van Cott. For each of the over 4000 place names indexed in the book are answers to such questions as: Where is it? What is its history? What is its importance? Who provided the name and when? What does it mean? Specific Section, Township, Range, and Altitude data is also supplied.
Please click the download button only once. The item will be saved to your desktop or downloads folder.
By downloading this item, you agree to abide by the terms and conditions detailed in the description for this content. This content is for non-commercial, educational use only. You understand that you must be a teacher, staff member, administrator or the student of a qualifying Utah educational institution. You may retain and use this content for educational purposes.
Media Type:
Utah Place Names
Grade Levels:
- 12
Subject Areas:
Social Studies
Ghost towns; abandoned towns; extinct towns;
UCME - Utah Collections Multimedia Encyclopedia
University of Utah. University of Utah Press
The contents of this article may be repurposed for non-commercial, non-profit, educational use.You may download and display or play this media item in perpetuity, with no time or frequency limitations.


text:
With a disclaimer like this, a website has to be good:
I have tried most of these things, and still live. However your experience may vary. I do not take any responsibility for any dammed stupid thing you may do to yourself, and am presenting this information solely for entertainment purposes.
What'choo talkin' bout, Willis?
...I'm glad you asked...
How'd you like some Fun Things to Do with Microwave Ovens?
I recommend NOT starting with a carton of eggs.
"[DANGER!] Similar to the 'tin can' method of major mayhem. In this case, the eggs all heat up, and go supercritical. This means that they are above the boiling point of water, but the strength of the eggshells holds them together - till one bursts, and the water inside instantly and all at once converts to steam. This smallish explosion naturally detonates all the other super-critical eggs. The result (same as for the can) is the blowing off of the door, and the coating of the surroundings in egg spludge."
This reminds me: the word 'spludge' isn't used often enough in everyday conversation.
I really hope this person is a home owner, not a renter ... and well insured. Then again, will insurance really cover the effects of putting a can of baked beans in the microwave for, say, an hour?
::::: | Sunday, Aug 06 2006 at 8:18 AM
::::: |
::::: | All Content © 2004-2016
::::: | Jalpuna is hosted by DreamHost


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The Youth enjoyed a night of Bowling on the 16th December 2008. Photos from the event are now available online HERE. Why not check them out and see how much fun our Youth enjoyed.
The event was organised by our Youth Leaders and their assistants…..and as you an see they joined in also!
Why not take a peek at our Youth page also, available HERE…. We desperately need ideas for new material and 'fun stuff'.


text:
Feeling Stuck In Your Car Loan? Might Be Time To Shop Around!
Some bills can't be changed. For other bills, though, a little legwork can make a big difference in your monthly payment. Your car payment is a great example. Refinancing your vehicle loan can lead to a lower monthly payment, a shorter payment term or both! It depends on various factors, including the value
Category: Credit Union News


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Plague Inc.: Mega Brutal High Score Guide: Virus
Sorry for the bad formatting.
Important Notes: In case you didn't know, getting severity will increase the dna you get from bubbles.
If I tell you evolve a symptom/transmission and it has already mutated, skip that instruction.
If Greenland/Iceland or some other island country's ports close, quit the game and restart this. I estimate this guide has a 70% success chance.
The thing that makes virus different from the other diseases is the high mutation rate and the cost to devolve. We want to utilize the pros of each plague and try to reduce the cons of the plague. We will do this by using the base oxidization gene (THIS IS ESSENTIAL.) The base oxidization gene lets you mutate transmissions in addition to symptoms and makes it easier to cure. I find this an extremely fair trade-off for getting a ton of free transmissions. The best thing about base oxidization is that mutating transmissions increases mutation chance (well most of them.) We want the ATP boost for a head start. The environment genes is your choice, though I prefer extremophile. In virus, we want to evolve a lot of symptoms. We don't need to focus on transmissions because we will mutate
them. The symptostasis gene lets us evolve symptoms without increasing their cost (normally whenever you evolve a transmission/symptom/ability, the cost of all the other transmissions/symptoms/abilities increase.) This will let us evolve a lot of symptoms (SYMPTOSTASIS IS ALSO ESSENTIAL.) Last but not least, we want the aquacyte gene. This will help with reaching the troublesome, cold countries as we will be starting in India. We might end up with unwanted symptoms. If you mutate total organ failure or hemohragic shock, devolve it. Otherwise you shouldn't.
We start with cysts, abscesses and hyper sensitivity. This gives us a good early boost. Then we get rash and sweating into skin lesions which gives us a huge spike in infectivity. Then we get coughing,
sneezing, pneumonia, nausea, vomiting, insomnia, paranoia, anaemia, haemophilia, diarrhea, pulmonary odema/fibrosis for the infectivity and severity. Don't worry if your disease gets discovered early, it should.
I am aware of the fact that you are getting lethality. In mega brutal, they added
genetic shift which increases the DNA costs of transmissions/symptoms/abilities bass on how many
people are infected. The more infected, the higher the cost. In fact, at the whole population infected, total organ failure costs 60 DNA! This is clearly unacceptable. We will need to get lethality earlier.
Then we get water 1/2, drug resistance 1, cold resist 1 and viral instability 1. Then we get air 1/2, cold 2, extreme bioaersol, genetic hardening 2 and drug resistance 2. At this point this starts getting a bit risky. We evolve necrosis, dysentery, insanity and systemic infection for the infectivity, severity
and lethality. At this point we wait for every country to become infected. If your DNA total gets
above 125, evolve a transmission of your choice. Once every country is fully infected or close to full, evolve total organ failure, hemohragic shock and internal hemorrhage. Once the world population
gets below 1,000,000,000 evolve genetic hardening 1/2/3 for reducing the cure percentage and increasing your score. Use your remaining DNA to evolve some symptoms to speed up the demise of the world. You should end up winning in about 300-350 days and about 10% cure. This should result in about 400,000 points.
I hope this guide helped you. :)
5 comments :
I tried your build a few times and while very effective at first I found out that the high lethality rate tends to make key countries close their borders before being infected. However, if I tried the same build enough times, I'll probably manage to get lucky on the random mutations to get it through smoothly. I am not really sure about the 70% success rate you mention ;)ReplyDelete
If I use some of your build but jam it up a little to integrate some patterns I like, I manage to make around 220k (344 days, 19% cure).
If I use my own current build however, I can get up to 311k.
Here is the way I do it if you are interested:
First of all, a low cure percentage is more important than a fast victory.
Genes combo:
- metabolic jump
- aquacyte
- symptostasis
- genetic mimic
- extremophile
Start in China.
If at the early stage, two consecutive mutations bring lethality, the games becomes much less likely to give a very good score. It might be possible to pull it off still, but I advise against it and you should reset the game right away. If you have no more than 1 minor lethal symptom to devolve, devolve it before it kills and gets detected yet.
1: Symptoms -> rash, sweat, skin lesions, coughing, sneezing
2: Transmission -> water 1, birds 1, water 2, birds 2
3: Abilities -> heat 1, cold 1 / drug resistance 1. Choose the mutation which boost the virus in the largest number of infected countries.
Middle game:
The Cure should have started but it takes quite some time before you get to 1%. When you reach this moment, focus on evolving drug resistance 1 (if you have not evolved it yet), genetic hardening 1 and 2. If during this phase a lethal symptom evolves, you keep it.
1: If the virus is already spread in many countries including countries with the first rank ability you have not yet done, do it.
2: Livestock 1 and 2.
3: Do now the final first rank ability if you have not done it already.
4: The cure should now have reach 1%, go to genetic hardening 2.
End game:
1: Evolve drug resistance 2, heat 2/blood 1. Africa often gets infected among the last and both options helps the virus to thrive in there. Blood 1 might be a little better as it is less expensive and will not increase the price of genetic hardening.
2: Evolve every level 1 and 2 remaining symptoms, seizures and insanity.
3: Wait for all countries to get infected while accumulating DNA points and letting random mutations enhance your virus. At this stage you should only devolve organ failure and hemorrhagic shock.
When all countries are infected, the cure should be around 12-15%. And you have between 130 and 180 DNA points depending on how lethal you virus is.
1: Evolve necrosis, diarrhea, internal hemorrhaging, immune suppression
2: You should then evolve the high lethality symptoms (organ failure, hemorrhagic shock and dysentery also if you have enough) but keeping at least 95-100 DNA points.
3: Until you get close to 200.000 infected people remaining, continue evolving symptoms that add lethality. You generally aim here for middle range cost symptoms with lethality. You keep the 95-100 DNA points necessary for the final move.
4: Evolve genetic hardening 1, 2 and 3.
My best finish is 328 days 14% cure for a score of 311k.
The cure finishes between 14 and 17% depending on luck about the random symptom mutations.
- OctaveJune 11, 2014 at 7:20 AM
For the 311k victory, the cure was at 11%.
I also just made a new personal high score of 348k in 308 days with 11% cure using my own build.
What is your highest score Lamteehee?
- OctaveJune 11, 2014 at 9:29 AM
I finally managed to get a big score with a mix of your strategy and mine.ReplyDelete
295 days, 7% cure
Score -> 519260
- Mr. AnonymousOctober 13, 2014 at 10:09 PM
Managed to get it done in 287 with score of 512260 and cure at 14%ReplyDelete
Bacteria is the first unlocked plague type in Plague inc.. In its description it says "Most common cause of Plague. Unlimited Potenti...
The Virus plague type is one of the 7 standard plagues in Plague inc.. It is unlocked by finishing Bacteria in normal or brutal difficulty...
Plague inc. is game made by Ndemic Creations and is available on the Appstore and Google play . It is a simulation game about spreading ...
AN UPDATED GUIDE FOR BACTERIA MUTATION 10 HAS BEEN POSTED. CHECK IT OUT HERE . After a lot of frustrating games, I was finally able to ...
The Prion plague type is the 5th unlock-able plague in Ndemic Creation's game, Plague Inc. Prion is unlocked by successfully finishing...
The Fungus plague is the 3rd unlock-able plague. It is unlocked by finishing the Virus plague in either normal or brutal difficulty( Virus...
This guide has been written and submitted by Patty. Submit your own guide to us now via our submit section or by sending them directly to...
The Nano-Virus plague type is the 6th out of the 7 basic plagues available when you get Plague Inc. It is unlocked by successfully finishi...
ATTENTION! A MUTATION 10 MEGA-BRUTAL GUIDE FOR FUNGUS IS OUT! IT MAY OR MAY NOT BE AS BAD AS THIS ONE. GO CHECK IT OUT! It took me sever...
The Parasite plague type is one of the seven basic plagues available once you purchase Plague inc. It's unlocked by finishing Fungus p...


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Product Description
Each one of our glorious seasons bring something special and winter is no exception. Our animal friends and the brave birds, who choose not to fly to warmer climes are our winter companions. We mustnt forget to look after them, especially when the ground is frozen and food is difficult to find. Greg Giordano is known for his exquisite paintings of our favourite feathered friends. Box size 30 x 30 x 5cm, completed puzzle size 68 x 49cm.


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Squad news
05 Oct 2012
Carlos Marchena is deportivo-la.coruna.com player of September; the Andalusian defender is one of the three players at the team that have played all the possible minutes in liga and is now the leader at Depors defense.
New season for the RCDLC.com Player of the Season Award; the rules havent changed at the peña; each member has the option to vote for the best three players in the official games of Depor; the votes are added and according to the teams global performance the players get points, which later are accumulated; the winner is the player with more votes at the end of the regular season.
Many people were doubting when Deportivo announced the signing of Carlos Marchena, some didnt like his past linked with Valencia CF, others thought he was too old and even too controversial, but in just two months he turned to be the leader of Depors defense and a fixed starter for Oltra. Actually, he, Evaldo Fabiano and Abel Aguilar are the only three players that have disputed all the possible minutes after the six first liga matchdays.
The peña members of RCDLC.com have noticed his job and the Andalusian defender was part of the more voted players in three of the four matches disputed in September, reason why hes the player of the month, the first on this season.
Despite the loss at home against Sevilla CF the peña members liked his work and Marchena was named as the best player in that game, one week before he was the second more voted man during the visit to Granada CF, in this game the most voted player was Nélson Oliveira, who scored the goal and also hit the crossbar in a polemic ghost goal that didnt count.
Early in the month, the ex-Valencia man turned to be the fourth player with more votes during the home clash against Getafe CF, in this occasion the player of the game was Riki. The only match in which Marchena wasnt part of the top list was in the heavy defeat against Real Madrid, in this last clash the man of the match was Aranzubia, followed by Abel Aguilar and Riki.
Ratings on the month:
|Vs Getafe (01/09/12)
|1st Riki - 7 points
|2nd Pizzi - 5 points
|3rd Aguilar - 3 points
|4th Marchena - 1 point
|PV: Laure +1 pt
|Collective Note: 2 (Medium)
|Vs Granada (16/09/12)
|1st Oliveira - 5 points
|2nd Marchena - 3 points
|3rd Bruno Gama - 1 point
|Collective Note: 1 (Poor)
|vs Sevilla (24/09/12)
|1st Marchena - 7 points
|2nd Valeron - 5 points
|3rd Evaldo, Aguilar - 2 points
|4th. Aranzubia - 1 point
|NV: Aythami, Juan Dominguez
|Collective Note: 2 (Medium)
Overall: Abel Aguilar is the current leader in the race for the RCDLC.com Player of the Season Award; the Colombian midfielder is almost doubling the points of another new signing: Pizzi, who is second at the table; Marchena is third after his solid run in September, just one point above Madrilenian striker Riki.
|Overall Table
|1st Abel Aguilar 22pts
|2nd Pizzi 14pts
|3rd Marchena 11pts
|4th Riki 10pts
|5th Bruno Gama 7pts
|6th Oliveira 6pts
|7th Valeron 5pts
|7th Aranzubia 5pts
|9th Manuel Pablo 4pts
|10th Aythami 4pts
|11th Evaldo 1pt
|11th Laure 1pt
|13th Juan Dominguez -1pt


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Hong Kong will lose out to other Chinese cities within five years if local lawmakers do not take quick decisions and clear important legislation, business tycoon Allan Zeman has warned.
The South China Morning Post quoted Zeman, who is the chairman of Ocean Park and Lan Kwai Fong Holdings, as saying that the city faces a major threat from Shanghai, where several big entertainment projects are due to be completed in the next three years.
He singled out the Legislative Council for criticism, saying it was dragging its feet on crucial matters.
"The chief executive [Leung Chun-ying] does not have the support in the Legislative Council. Legco is blocking government legislation … it is filibustering on the budget bill. Everything is so slow," Zeman was quoted as saying.
The comment came after lawmakers submitted 1,917 amendments to the budget bill, which is likely to trigger a marathon debate running from next Wednesday until June at the earliest, the report noted.
– Contact HKEJ at [email protected]


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The enthusiasm for the approach and build-up app Clash of Clans is not broken. Many players have been around for several years and new players are arriving. For all those who have start the sport, we have gathered the best Clash of Clans tips that you should know in any case if you want to get one of the great Clashers.
Clash of Clans Free Gems is one of the great successes in the Google Play Store. The Free2Play game with likely in-app acquisitions from Supercell generates many million dollars a day. The mix of building approach and multi-player keeps a large number of players at bay, but it calls for part of years to get it into the bigger levels and leagues inside the circle of top players. With no tolerance and high frustration, you are very prone to the in-app purchases, and a few players basically sink in the game.
Clash of Clans Tips
Ultimately, you should established a good two years – if you don't want to fall sufferer to an in-app purchase – until you could have expanded your base and troops so as to play at the pinnacle. If this kind of takes you too long, you really have to put real money, however the fun is basically very expensive. In addition , you should avoid using a clash-of-clans-hack: These secrets and cheats do not job and just offer you with trouble
Remain calm and conserve jewels
Jewels are the money with which you are able to advance the course of the sport or your development. With jewels you can:
Fill resources.
Elixir lovers, elixir workouts and goldmines.
Unbalance helpful improvement and construction assignments.
Buy protecting shields.
Special place boxes.
Tidy up, so get rid of trees, bushes and mushrooms.
From cheats, which usually promise you free gems, you should alternatively leave the fingers. On the one hand, Supercell is without understanding of these illegal activities on your consideration and will obstruct it quite quickly if they happen to be aware of that, and on the other hand, viruses, trojans or other viruses are often concealed behind such offers.
But once you vigilantly clean up the jewels and use them cautiously – this means clear focus – you can apply well and sometimes even get a development slump or possibly a development.
Trophy hunters or perhaps farmers?! Desired goals in the game
Essentially there are three strategies to deal with the game:
Harvesting to receive as many methods as possible.
Obtain trophies and climb into the leagues.
Advance both equally.
There is no set-up in the game, so you need to concentrate. You are able to freely determine in which way the game brings you the most fun. For many, it is critical to work with bringing the town to the optimum limits, web browser, to raise all the troops and buildings to a maximum, other folks want to be the greatest hero of the greatest league and it is also very appealing to focus on completing the To formulate achievements, which also add jewels to you incidentally. Since the big December revise, the facilities have sadly become a lot more difficult. As you can constantly rebuild your base, you could have ample opportunity to try out diverse strategies.


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Madonna Denies Adoption Rumors
Entertainment 26.01.2017 POPCREED 0
Pop star Madonna has denied the recent rumors that she has applied to adopt two more children in Malawi.
The statement came after a Malawian government spokesperson told news outlets that the 58 year old singer had appeared in court and had "filed an application expressing interest" to adopt.
Madonna is currently in the African country, but said her visit was strictly for charity purposes.
"The rumors of an adoption process are untrue," she revealed in a statement.
"I am in Malawi to check on the children's hospital in Blantyre and my other work with Raising Malawi and then heading home."
Court spokesman Mlenga Mvula had told news agencies earlier on Wednesday the singer had appeared in High Court, applying to adopt two children. Madonna previously adopted two children from the African country: David Banda and Mercy James.
The star's connection with Malawi dates back to 2006, when she established the Raising Malawi charity, with the goal of improving children's lives.
Madonna also has two other children – Lourdes and Rocco – from her previous relationships.
No comments so far.
Be first to leave comment below.


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Today the sewing machine was out so I could do some mending and while it was set up I made this quick cactus hoop art.
The inspiration for this came from a little plant that was a gift from Little L. I don't know who thought it was a great idea to glue things on to a plant but when I tried to remove the hat I snapped the top of the plant. I've squashed it back together hoping that it will heal its self and not die on me.
The felt pieces were all machine sewn on
then the embroidery and wobbly eyes were added.
These are the pattern pieces that I made to make it.


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Cuina del bolet.
By the end of September until November around Catalonia is celebrated gastronomic culinary fest of mushrooms where a lot of restauranetes offer mushrooms in their menus.
Mushroom picking is one of the most popular autumn activities in our country. This activity is usually in family or friends and as well as having fun it normally ends up with a good meal of mushrooms, picket up by us, or in a good restaurant that will serve us dishes of mushrooms in countless ways.
Autumn is time of fairs of mushrooms in Catalonia, among which we highlight those taking place in the Bergadà, Cardona (fair Llanega), Llagostera, Maresme (San Iscle of Vallalta), etc.
To visit these fairs can be the perfect excuse to enjoy the Mushroom cooking


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It seemed this particular topic had been chasing me lately from classroom to emergency room, so I decided to investigate. I asked my "smart phone" for a little assistance and found out she was talking about a Harvard professor named Eban Alexander who reports experiencing heaven during a 7 day coma resulting from bacterial meningitis--Dr. Alexander who taught at Harvard medical school and now commutes to the University of Virginia from Lynchburg, VA, reports that while his brain was in a disconnected state (the cortex which is considered the primary location of memory and consciousness was being attacked by the illness) he experienced heaven. (See video link below)
However, two elements of a portion of reported NDEs seem to remain inadequately explained in the research I found--the out of body awareness and advanced cognitive functioning including awareness of individuals and events that one would otherwise have no access to in their physical state. Some researchers are concluding that "self" exists independent of the body and is not a product dependent upon brain function--that there is perhaps an immaterial aspect to man afterall (van Lommel, 2011). What strikes this reader as most interesting are the reports of the NDE experiencer 1. seeing a deceased person who was thought to be alive (ex. Uncle Carl died in Alaska and Nephew Sam experienced an NDE in which he was revived and reported seeing Uncle Carl at which point his parents reported Sam having no previous knowledge of Uncle Carl's passing or a call comes in saying Uncle Carl just died). 2. seeing a deceased person otherwise unknown to the experiencer and upon being revived the report is cooroborated that the person existed (ex. the experiencer reports communicating with a "cousin" who unbeknownst to the experiencer was miscarried years before by an aunt.) (Greyson, 2010).
I am not about to jump on one boat or another and say all of these NDEs are true or that they aren't--a tendancy which seems prevalent among some of my friends---What I will say, is that although healthy skepticism may be warranted for such claims, as a believer in Christ and the afterlife He came to bring us, at some point I need to not just say, but also believe that "it's possible" He's given glimpses to others. I need to get over my knee-jerk reaction when someone brings up the topic of the paper-thin wall between this life and the next, and really start thinking and researching biblically through what I believe and why. I just wish we had a more detailed account from Lazarus of Bethany of his experiences while dead--it might help to see how the accounts we are hearing in pop culture and scholarly research articles line up.


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|"Kim Haase (JIRA)" <j...@apache.org>
|[jira] [Created] (DERBY-5198) XPLAIN table documentation needs some cleanup
|Tue, 19 Apr 2011 14:25:05 GMT
XPLAIN table documentation needs some cleanup --------------------------------------------- Key: DERBY-5198 URL: https://issues.apache.org/jira/browse/DERBY-5198 Project: Derby Issue Type: Bug Components: Documentation Affects Versions: 10.7.1.1 Reporter: Kim Haase Assignee: Kim Haase Priority: Minor While working on DERBY-5184 (table cleanup), I noticed that in some of the XPLAIN style tables topics there remain some questions that were not answered by reviewers and that managed to make it into the final documentation. These should be fixed separately from DERBY-5184, which focuses on formatting rather than substantive questions. I'll list the problems in a comment. -- This message is automatically generated by JIRA. For more information on JIRA, see: http://www.atlassian.com/software/jira
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Frequently Asked Questions
Answers to common questions about underfloor heating.
How long will the underfloor heating pipe last?
The pipe we supply is guaranteed for 50 years but there is no reason why the pipe can't last for hundreds of years.
Can I retrofit underfloor heating in my house?
If you have suspended floors then it is fairly easy to lift the floorboards and fit the insulation, underfloor heating pipe and screed between the joists. If you have solid floors, then you will usually need to dig down to gain the necessary depth. You will have to decide whether the cost of doing this is worth it.
Can I have an underfloor heating system downstairs and radiators upstairs?
Yes, so long as you have one zone valve and timer for the underfloor heating system and a separate zone valve and timer for the radiator system. Underfloor heating needs to be on for longer periods of time than radiators so they would wouldn't work correctly if they were both using the same timer.
What happens if a pipe gets damaged?
Every care should be taken not to drill or cut into the floor once the underfloor heating pipe has been laid but if an accident did happen then the pipe would have to be accessed and the damaged part cut out. A straight connector or a new section of pipe and two straight connectors could then be fitted to repair the pipe.
Is underfloor heating cheaper to run than radiators?
Because underfloor heating runs at a lower temperature than radiators, underfloor heating can be 10-15% more efficient. Underfloor heating does need to be on for a lot longer than radiators though so isn't as efficient as some people may claim. Using the correct floor construction is the best way to achieve optimum efficiency.
Will underfloor heating work in my conservatory?
Underfloor heating will work well in a conservatory if it has been designed to give an output high enough to meet heat losses. There is often limited wall space in a conservatory to fit a large enough radiator whereas underfloor heating is essentially a giant radiator spread across the whole floor.
Need an Estimate? E-mail your plans to email@example.com


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Victor's lasting legacy
We celebrate Remember a Charity Week by talking to Victor Coles, a John Christie Society Member, about what it is that inspired him to leave a lasting legacy.
When did you first start coming to Glyndebourne?
I first started coming to Glyndebourne in 1970. I was 18 years old and must have been in the last year of school as I had to get the headmaster's permission to come – because, of course, it involved taking the afternoon off! I remember I didn't own my own dinner jacket so I bought one second-hand at a country fair for – I think – five shillings.
What was that first performance?
The first performance I saw was The Magic Flute. I was in the very back row of the Upper Circle of the old house and it was an amazing experience. I've been coming most years ever since. I'm up to my 66th visit this year.
What do you love most about Glyndebourne?
Glyndebourne's insistence on excellence. The new house, with its acoustics, in my experience, is the best in the world.
Why did you decide to leave a legacy to Glyndebourne?
Some years ago Glyndebourne ran some workshops in London and I was asked to participate. The suggestion was that Glyndebourne set up this arrangement where you could leave a gift in your will. I thought that was a good idea because my daughter might benefit from it.
What do you hope your legacy will achieve?
There's a future audience out there somewhere and they need to be able to see the same standards I've enjoyed over the years.
I'm particularly interested in reducing the average age of the audience through Glyndebourne's New Generation Programme. We – the audience – are a bit of a dying breed in terms of age and we need to encourage youngsters who would normally find Glyndebourne a bit inaccessible, even with all the efforts Glyndebourne make – and they are considerable.
What do you like most about being in the John Christie Society?
You have a sense of feeling wanted. In the autumn we get invited to a lunch and a rehearsal and that makes us feel a bit special.
What would you say to those considering leaving a gift to Glyndebourne?
Don't hesitate. I've never regretted it and I think it enhances your visit. I feel more a part of the fabric when I come and it's one way of leaving something to future generations.
Help us secure Glyndebourne's future
To find out more about leaving a gift to Glyndebourne and becoming a member of the John Christie Society, please visit glyndebourne.com/legacy.


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Military Bios
Lorna B. Estep:
Military Branch:United States Airforce
Selected for reassignment as Deputy Director for Supply Management, Headquarters Air Force Materiel Command, Wright-Patterson Air Force Base, Ohio.
Lorna B. Estep, a member of the Senior Executive Service, is Deputy Director of Logistics Readiness, Office of the Deputy Chief of Staff for Installations and Logistics, Headquarters U.S. Air Force, Washington, D.C. The directorate is responsible for organizing, training and equipping 33,000 people worldwide in the Air Force logistics readiness career field. In addition, logistics readiness integrates Air Force agile combat support concepts, doctrine, exercises and sustainment policies with the Office of the Secretary of Defense, defense agencies, the Joint Chiefs of Staff, and combatant commanders and major command staffs. The directorate executes the Combat Support Center mission, and establishes and implements Air Force materiel management, fuels, vehicles and equipment policy. Logistics readiness defines and integrates installations and logistics management information system requirements for the Global Combat Support System, and it plans and coordinates transformation and innovation for logistics. Additionally the directorate oversees the Air Force Logistics Management Agency at Gunter Annex, Ala., and the Air Force-controlled joint personnel shipping offices across the United States.
Ms. Estep started her career as a Navy logistics management intern. As former Director of the Joint Center for Flexible Computer Integrated Manufacturing, she developed and coordinated joint requirements, pilots and programs for logistics, engineering, and production and repair within the Department of Defense and its industrial base. These pilots included generic techniques for digital data acquisition and management across weapon systems, including AEGIS, M1A2 and the FA-22. As the first program manager for Rapid Acquisition of Manufactured Parts, she implemented one of the first integrated and agile data-driven manufacturing systems. Other automation projects she managed include material handling systems, and warehouse, distribution control and transportation management systems.
Ms. Estep served as Technical Director of Information Technology Initiatives at the Naval Supply Systems Command. In this position, she directed the development, integration and implementation of complex technical data systems and other advanced information initiatives for the Navy. As the Director of Joint Logistics Systems Center, Ms. Estep had the duties of a commanding officer for a major subordinate command. In addition, she acted as the Logistics Community Manager, an emerging organization to coordinate and implement the revised Defense Department logistics strategy for achieving Joint Vision 2010 through modern information techniques and processes. She also served as the Chief Information Officer for Naval Sea Systems Command, where she was responsible for establishing and managing command-wide information technology architecture, capital planning, policy, IT budget and security. She also managed the headquarters' campus IT operations. Prior to assuming her current position, she was the Executive Director, Headquarters Materiel Systems Group, Wright-Patterson Air Force Base, Ohio. The group is a direct reporting unit of the Electronic Systems Center at Hanscom Air Force Base, Mass. The MSG manages more than 200 of the command?s business and logistics information systems.
1978 Bachelor of Science degree in biology, University of South Florida, Tampa
1982 Master of Science degree in administration, George Washington University, Washington, D.C.
1989 Federal Executive Institute, Charlottesville, Va.
1. August 1978 - August 1980, Navy logistics management intern, Fleet Material Support Office, Mechanicsburg, Pa.
2. August 1980 - August 1981, transportation specialist, Naval Supply Systems Command, Arlington, Va.
3. August 1981 - December 1983, program control team leader, Naval Supply Systems Command, Arlington, Va.
4. January 1984 - June 1986, branch Director of Warehousing, Equipment and Systems, Naval Supply Systems Command, Arlington, Va.
5. June 1986 - June 1992, Manager, Rapid Acquisition and Manufacture of Parts Program, Arlington, Va. (December 1991 - December 1993, Director, Joint Center for Flexible Computer Integration Manufacturing, North Charleston, S.C.)
6. January 1994 - January 1995, Technical Director, Information Technology Initiatives, Naval Supply Systems Command, Arlington, Va.
7. January 1995 - April 1996, Director of Enterprise Integration, Naval Supply Systems Command, Arlington, Va.
8. April 1996 - July 1997, Director of Plans, Programs and Resources, Joint Logistics Systems Center, Wright-Patterson Air Force Base, Ohio
9. July 1997 - October 1998, Logistics Community Manager and Deputy Director, later, Director, Joint Logistics Systems Center, Wright-Patterson AFB, Ohio
10. October 1998 - March 1999, Chief Information Officer, Naval Sea Systems Command, Arlington, Va.
11. March 1999 - June 2003, Executive Director, Headquarters Materiel Systems Group, Wright-Patterson AFB, Ohio
12. June 2003 - present, Deputy Director of Logistics Readiness, Office of the Deputy Chief of Staff for Installations and Logistics, Headquarters U.S. Air Force, Washington, D.C.
Armed Forces Communications and Electronic Association International
Senior member, Society of Manufacturing Engineers
International Advisory Board for Concurrent Engineering
1990 National Capital Region Award and national nominee, Society of Logistics Engineers
1991 Navy Civilian Meritorious Medal
1993 Navy Civilian Distinguished Service Medal
1993 Military adviser, Lean Production Sub Panel, Defense Science Board
1980 - 1995 Outstanding performance awards
1981 - 1992 Sustained superior performance awards
Acquisition professional
Level III Program Management
Copyright 2005 -
Military Bios


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Walkers Gold tin is filled to the brim with their famous pure butter shortbreads - fingers, rounds, ovals and triangles but in a cute miniature version.
The gold oval tin is beautifully embossed with Scottish thistles and comes with a special sleeve to show how much you love that special person in your life.
Tin Dimensions 7.1" x 4.4" x 2.4"
From Anonymous of Salina, Kansas on 1/28/2019.
GREAT product.! Can hardly wait to give this as a gift!
Gift I haven't given yet...a stocking stuffer!
From Rick of Red Oak, Texas on 8/18/2018.
Bought for a gift...a stocking stuffer! My wife & I both LOVE WALKER'S PRODUCTS!!!!!
Great Gift
From Pauline Wantland of FARMERS BRANCH, Texas on 7/14/2018.
What a nice gift to receive or give. Just the perfect size and the cookies were great!
Nice Gift
From Anonymous of Cathedral City, California on 5/4/2018.
beautiful tine giving as gift to family member. filled with the best shortbread cookies ever!
I love the "I love you" tim
From Salome of Cleveland, Ohio on 3/2/2018.
I am a big fan of Walker shortbread - and a big fan of your lovely tins. I have two as gifts and kept one for myself!
Ingredients: wheat flour (wheat flour, calcium carbonate, iron, niacin, thiamin), butter (milk) (31%), sugar, salt.
For allergens, including cereals containing gluten, see ingredients in bold. May also contain nuts. Suitable for vegetarians and certified Kosher OUD. Store in a cool dry place.
Nutrition Facts
Serving Size: 7 pieces (29g). Servings per Container: About 6. Amount per
Serving: Calories 150. Calories from Fat 80.
Total Fat 8g (13%), Sat. Fat 5g (26%), Trans Fat 0g, Cholest. 25mg (8%),
Sodium 95mg (4%), Total Carb. 17g (6%), Fiber Less than 1g (2%), Sugars 5g,
Protein 2g. Vit A 6%, Vit C 0%, Calcium 2%, Iron 2%). Percent Daily Values (DV)
are based on a 2,000 calorie diet.
Shopping Cart
is currently empty
Walkers Shortbread Ltd, Aberlour House, Aberlour on Spey, Scotland, AB38 9LD
Company No. SC0 63233


text:
ISSN (Print): 1574-8936
ISSN (Online): 2212-392X
Volume 14, 8 Issues, 2019
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Special Issue Submission
In-Depth Exploration of miRNA: A New Approach to Study miRNA at the miRNA/isomiR Levels, 2014 : 9 5; 522- 530
Li Guo , Hui Zhang, Yang Zhao, Sheng Yang and Feng Chen
View Abstract Rights and Permissions
Plant Bioinformatics: from genome to phenome
Guest Editor(s): Ming Chen, Ziding Zhang, Youhuang Bai
Tentative Publication Date: March-April, 2015
Download Description
Application of Novel Computational Methods in Molecular Biology, Biomedicine and Biopharmacy
Current Bioinformatics, Volume 11, Number 1
Guest Editor(s): Yudong Cai
I am very much satisfied with the review process and the communication made by the team for my manuscript. I have struggled a lot to prepare the pictures as per the requirements. But your team has patiently given feedback about the corrections and finally agreed to approve. Really, i am very much thankful to that.
Dr. R. R. Rajalaxmia (Department of CSE, Kongu Engineering College, Perundurai, Erode, TamilNadu, India)
27 Abstract Ahead of Print are available electronically
14 Articles Ahead of Print are available electronically
The success of Bioinformatics in recent years has been prompted by research in Molecular Biology and Molecular Medicine
in several initiatives. These initiatives gave rise to an exponential increase in the volume and diversification of data, including
next generation sequencing data and their annotations, high-throughput experimental (omics) data, biomedical literature, among
many others. Systems Biology is a related research area that has been replacing the reductionist" view that dominated Biology
research in the last decades, requiring the coordinated efforts of biological researchers with those related to data analysis,
mathematical modeling, computer simulation and optimization.
The accumulation and exploitation of large-scale databases prompt the development of new computational technology and
research on these issues. In this context, many widely successful computational models and tools used by biologists in these
initiatives, such as clustering and classification methods for omics data, are based on Computer Science/ Artificial Intelligence
(CS/AI) techniques. In fact, these methods have been helping in tasks related to knowledge discovery, modeling and
optimization tasks, aiming at the development of computational models so that the response of biological complex systems to
any perturbation can be predicted.
In this context, the interaction of researchers from different scientific fields is, more than ever, of foremost importance,
boosting the research efforts in the field and contributing to the education of a new generation of bioinformatics scientists. The
Practical Applications in Computational Biology and Bioinformatics (PACBB) conference has been contributing to this effort,
promoting this fruitful interaction over the last 7 years. This special issue gathers four contributions, selected and significantly
extended from the rich PACBB'15 technical program, which included papers spanning many different sub-fields in
bioinformatics and computational biology.
This volume gathers four extended articles selected from the work presented at the PACBB'2015 conference, showing
distinct and meaningful practical applications of bioinformatics and computational biology. These range from text mining, to
next generation sequencing and gene expression data applications.
Calderon-Mantilla et al. propose a pipeline architecture for inferring and visualizing gene networks from expression data,
applied to the specific case of coffee plants [1]. Rodriguez-Gonzalez et al. present a comparison of two distinct text mining
approaches for extracting diagnostic related knowledge from MedLine Plus articles [2]. The work by Graña et al. proposes
nextpresso, a pipeline for the analysis of next generation sequencing (RNA-seq) data that covers the most common
requirements of these experimental data [3]. Finally, the work by Fernandez-Gonzalez et al. addresses a relevant problem in
text retrieval, namely the influence of class imbalance when developing classifier models for assessing relevant biomedical
literature [4].
The major feature of our current life sciences, is the rapid increase of biological data, which are presented in many forms,
and reflect the characteristics of biological systems at various levels, including genome, transcriptome, epigenome, proteome
and metabolome etc. This is the so-called biological big data we are facing. Biological big data bring both challenges and
opportunities to bioinformatics. Tools and techniques for analyzing big biological data enable us to translate massive amount of
information into a better understanding of the basic biomedical mechanisms, which can further be applied to translational or
personalized medicine.
This thematic issue with a theme of "Bioinformatics in Biological Big Data Era" aims at extensively showing the latest
development and achievements in Bioinformatics in this biological big data era. The ten papers in this thematic issue were
selected from the 1st CCF Bioinformatics Conference (CBC 2016), which was sponsored by China Computer Federation (CCF).
The selected papers cover methods and algorithms for processing biological big data in addressing various bioinformatics
issues. Before submitted to the special issue, these papers have gone through strict reviewing organized by CBC 2016. Further
reviewing was organized by the guest editors.
In what follows, we give a brief review of the 10 papers included in this thematic issue.
Liu et al. in their paper "Sparse linear modeling kinase inhibition network for predicting combinatorial drug sensitivity in
cancer cells" used a sparse linear model called uncertain group sparse representation (UGSR) to infer essential kinases
governing the cellular responses to drug treatments, based on the massively collected drug-kinase interactions and drug
sensitivity datasets over hundreds of cancer cell lines [1].
In the paper "TagNovo: A dictionary based approach to predict peptide theroy spectra" Wang et al. presented a new
theoretical spectrum prediction model called TagNovo, which builds a "tag dictionary" from exiting spectrum library and is
used for theory spectrum prediction [2].
In the paper "Large-scale Investigation of Long Noncoding RNA Secondary Structures in Human and Mouse" by Guo et al.
the authors conducted a large-scale investigation of lncRNA secondary structures especially for hairpin structural motif in
human and mouse based on computational prediction using the RNAfold software, and found that the secondary structures of
lncRNAs have many characteristics, most of which are similar with those in mRNAs [3].
Nie et al. in their paper "Prediction of protein S-Sulfenylation sites using a deep belief network" developed a computational
method DBN-Sulf to effectively predict S-sulfenylation sites by using optimally extracted properties based on Deep Belief
Network (DBN) with Restricted Boltzmann Machines (RBMs). DBN-Suf shows significantly better performance than the
existing methods [4].
In the paper "Feature identification for phenotypic classification based on genes and gene pairs", Su, Zhang and Pan
proposed a new algorithm called FSGGP to select both feature genes and feature gene pairs on the binary-value gene
expression data [5].
Chan et al. in their paper "MyPhi: Efficient Levenshtein Distance Computation on Xeon Phi based Architectures"
introduced MyPhi, an ultra-fast implementation of the Myers algorithm on Intel Xeon Phi based architectures for efficiently
computing Levenshtein Distance between genome sequences [6].
The paper "A Metric on the Space of Rooted Phylogenetic Trees" by Wang and Guo proposed a new metric on the space of
rooted phylogenetic trees, which can be calculated in polynomial time with the size of the compared trees [7].
Liao et al. developed a method to classify Small GTPases and non-small GTPases in their paper "Classification of small
GTPases with hybrid protein features and advanced machine learning techniques" [8]. In the paper "Identification of Attention
Deficit/Hyperactivity Disorder in Children Using Multiple ERP Features", Li et al. used non-invasive event-related potential
(ERP) features for Attention deficit hyperactivity disorder (ADHD) prediction [9]. The paper "Low Rank Representation and
its application in bioinformatics" by You, Cai and Huang reviews the theoretical and numerical models based on low rank
representation and their applications in bioinformatics area [10].
This thematic issue is the result of many people's contribution, support and cooperation. We appreciate the authors for
submitting their works to this thematic issue, and we thank the reviewers for their hard work in reviewing the papers. We also
thank the Editor in Chief and the staff of Current Bioinformatics for their valuable help to make this issue possible.
With the development of sequencing technologies, a wide variety of biological data including DNA, RNA and protein sequences and gene expression profiles were generated and accumulated. These data are an external manifestation of acting mechanism of the cell. How to discover cellular mechanism through these data is a vast challenge that current scientists are faced with. The computational approaches including bioinformatics and system biology have proved essential to analyze these complicated data, as Markowetz declared that all biology is computational biology [1]. Recently a number of computational techniques and theories such as BLAST [2, 3] machine learning [4-7] and network theory [8-10], have facilitated the discovery of molecular structures and functions. Therefore, this thematic issue is intended to summarize recent progress of these computational techniques and theories in genomics and proteomics. Comparison between molecular sequences is very helpful to explore evolutionary relationship among different tissues, organisms or species and further to functional analysis. It is not an exaggeration to say that comparison between molecules is an important foundation of life exploration. Natural vector is a method of characterizing protein or DNA sequences and is applicable to classification and evolutionary analysis [11, 12]. Yu [13] reviewed the natural vectors method and application of it in the virus phylogenetic Classification.
Biological images are useful especially to phenotype quantification. High-throughput and quantitative biological phenotypes from images are increasingly becoming important to both the quantification of phenotypes and the visualization of biological molecular structure and activity. Bioimage informatics is becoming a new area of exploring life [14]. Chen et al. [15] discussed the major studies based on biological images and summarized the computational techniques of biological image analysis.
Long noncoding RNAs (lncRNAs) are transcripts with more than 200 nucleotides, and belong to a type of non-protein coding RNA. LncRNAs have recently been discovered to perform a variety of functions [16]. However, the identification of lncRNA is challenging [17]. Yao et al. [18] reviewed the computational strategies of recognizing lncRNA and current progresses, and discussed existing difficulties in the prediction of the lncRNAs especially by using machine learning methods.
Biomedical data are commonly big data which require both high-performance computers and high-effective computational methods. Deep learning proposed by Hinton et al. [19] is becoming a dazzling research field and makes machine intelligence advance a big step. Peng et al. [20] reviewed the application of deep learning in the omics data processing, biological image processing and biomedical diagnosis and discussed challenges.
With the development of meteorological science, a large number of meteorology data, such as temperature, humidity, rainfall, air pressure, wind speed and so on, have been collected. So how to identify the key meteorological indexes causing an epidemic? How to integrate these key meteorological indexes to predict the epidemic? These become a vital task for us now. Liu et al. [21] reviewed two categories of model of prediction of the epidemics related to meteorological factors: deterministic models and stochastic models.
Single-nucleotide polymorphism known as SNP is referred to as the variation of a single nucleotide that occurs at a specific position in the genome. SNP was found to be associated with a wide range of disease or traits [22], such as inflammatory and autoimmune disorders [23], Alzheimer's disease [24] and breast cancer [25]. The study of SNP-disease associations will facilitate the promise of precision medicine [26]. Li [27] reviewed computational methods of identifying SNP-disease association and discussed improvement directions: data quality improvement, high-performance computing platform and advanced computational method.
Although most genes have been detected, little was known about its functions. Numerous computational methods have recently been proposed to find gene functions. Loh et al. [28] summarized these computational methods, compared them and analyzed their strength and weakness.
Protein post-translational modification (PTM) is a biochemical reaction which occurs after translation and before protein synthesis, covalently modified by different functional groups. The PTMs involved in every cellular process of life is a key regulating mechanism in the cell [29-32]. The first important step to explore PTMs is to identify PTM types and sites. Currently, the biochemical or biophysical experiments and the computational approaches are parallel to complement one another for identifying PTMs. The computational predictionsgenerally consisted of data collection, representation of PTMs (feature extraction), training the known samples and prediction new samples. Therefore, the feature extraction occupies a central position in the computational prediction of PTMs. Huang [33] reviewed the methods of feature extraction which have recently been developed for PTMs prediction and discussed several properties of it.
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Spark the Change is a global movement that aims to inspire change and rethink the future of work. We bring together Business Leaders, Academics, and Disruptors who already went through a positive change before, and are keen to share their learnings.
We believe in the power of ideas and in the ability to question everything we do. Spark is about bringing the right people in the right place in order to start the right conversations that will help you innovate and change.


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Talk radio host and author of "The Liberty Amendments: Restoring the American Republic," Mark Levin criticized the Obama administration's ISIS policy by declaring "we're surrounded by knuckleheads, and the problem is, they're supposed to be protecting the country" on Wednesday's "Hannity" on the Fox News Channel.
"For him, the truth is, it's about politics. It's about containing this issue politically, for him, so he can focus on fundamentally transforming America, and this is a very serious matter to understand. So the generals and the military see this quite differently than our very political president, who really doesn't want to defeat this enemy," Levin stated.
He also argued "I honestly don't think he [Obama] gives a damn. As hard as it is to believe. How else do you explain him not securing the southern border? How else do you explain him being on vacation as this is breaking out? … The fact of the matter is if this is a war and we want victory, we can defeat them. We can wipe these cockroaches out. If he wants to do something short of that, obviously he can, but I think it's time for Mr. Boehner and Mr. McConnell, and people to rise up and say 'we want to know if you want victory, if you're going to call this a war, we will do a declaration of war, but we're not going to piddle around like this for political reasons.'"
Follow Ian Hanchett on Twitter @IanHanchett


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Devon delivers a difficult and rewarding work atmosphere that emphasizes teamwork, results and, most importantly, honesty and integrity. With the boost of IT positions and applications general comes the advents of ever escalating databases and the will need for administration of those caches of info. San Antonio is a college town that is household to many recognized institutions of studying that in fact offer education applications for high demand jobs. The Pharmacist can expect a wide variety of salary presents these days, from $20,000 to more than $120,000. Assemblers are have to have in Utah for Aircraft Structure, Surfaces, Rigging, and Systems. The jobs that are advertised and the ones we can obtain are occasionally diverse.
At least 75,000 job openings are situated in largest clusters in NYC ( far outnumbering any other), San Francisco, Chicago, Seattle, and Atlanta. The most effective-compensated jobs are located in San Jose, California New York City and San Francisco. Educational jobs include teachers of nurses and allied well being skilled, as well as Biological Specialists, another targeted field joining Aerospace in metro and state financial improvement plans.
Nevertheless, Renewable Energy is responsible for a substantial segment of new jobs advertised from 2014 forward. Considering the fact that the recession occurred, a lot of folks lost their jobs but now you can simply see the difference. There are so lots of good jobs that spend better than teaching he can do, but getting the capacity to teach is an significant back-up for him. These all-vital employees deliver quick- and extended-term visions for the company's technology wants and ambitions. I agree with you in your hope for more growth and for highlighting of excellent jobs that no one particular knows about.
A total of approximately 80,000 oil jobs appeared in advertisement in September 2014, up from 66,000 jobs that had been advertised in December 2012, up from an average of 51,000 jobs in 2011. Right after a higher peak in January 2011 and a decline in 2012, Anti-Corruption jobs are rising is advertisements in the Monetary, Healthcare, Aerospace, and Government/Defense Industries. I'm suitable in the middle of altering jobs in Atlanta, GA (which is a single of the highest paying markets thankfully).
The latter figure is an improve of about 19{2a93735a54d6ee8bbdcdf83abb1b48ecf23f2deb16e310e6b2c1776a2899df79} more than the 16,000 jobs open two years previously in the course of both September and December 2012. From January 2015 to April 2015, the list of high-demand jobs in the USA remained the similar as for 2014, with Truck Drivers rising above Restaurant Jobs. I would like to see you take into account the new jobs becoming created via various avenues of Net Advertising or other kind of revenue people create making use of the online.


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Year 6 celebrate World Book Day.
We had a 'Mad Hatter', James Bond, The Queen of Hearts, a Cheshire cat, a cat in a hat, a wimpy kid, a host of Harry Potters,'Wally', Verruca Salt, Sir Tristan (a little known Knight of the round table!), Superman and many more.
Survey Time
year 6 have been developing products and they need too do some market research, would you help. Please take a little while to answer theses surveys, who knows it could be your ideas that get made!
All website content copyright © Newburn Manor Primary School
Website design by PrimarySite


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Editor's Note: Toni Morrison, author of, among other works, "Beloved," was awarded the Nobel Prize for literature in 1993. What follows is an expanded version of her conversation with Michael Silverblatt, which recently aired on Bookworm, his weekly radio show about writing and books that is broadcast Thursdays at 2:30 p.m. on KCRW-FM (89.9).
Michael Silverblatt: I recently wrote Toni Morrison a letter knowing that the movie of "Beloved" would be coming out and wanting, not even having seen the film, to talk about the book. It's my sense that after a movie hits the public, a book is altered by it. There are things that we find in language, in the shaping and writing of literature, that a movie cannot touch, not because it doesn't want to or because it's inadequate but because they are different forms.
People don't usually talk about what's at the center of "Beloved." They talk instead about a story that actually occurred in the days of slavery, one in which a woman killed her children rather than see them brought back into slavery, back to the life she led on the plantation.
This is the background of the book, but you have also brought to it the question--which is also the question in your two recent books, "Jazz" and "Paradise"--what kind of love is too much? When does love of another eclipse the love of the self? It seems to me that this question--how much of the self can you give--is central to you as a writer.


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Transport for New South Wales faced the challenge of constructing a grade-separated southbound freight line beneath three heavily trafficked electrified suburban railway lines, without disrupting service to the North Sydney rail network.
It was necessary to navigate surface rock outcrops on the eastern embankments while ensuring minimal disturbance to surface settlement.
Mott MacDonald was appointed as technical advisor subconsultants for the concept design phase. We assessed several alternate underpass construction options with the primary aim of eliminating the previously selected cut-and-cover approach to reduce construction time and disruption to mainline services above the underpass.
Drawing on finite element analysis (2D and 3D) and the multidisciplinary engineering expertise of our team, we demonstrated the feasibility of the driven tunnel option.
The selected tunnel option included movement of the tunnel alignment north by about 200 feet (60 meters), resulting in more favorable geological conditions and a deeper tunnel situated directly beneath the operational railway lines.
Construction commenced by inserting arrays of canopy tubes 39 feet (12 meters) long ahead of the tunnel under the operational tracks above.
This allowed full construction of the driven tunnel with a one-pass shotcrete lining within an 8-month period, compared to two to three years for the cut and cover option, with no disruption to train services.


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Woman throws shoe at Hillary Clinton during speech at Las Vegas casino• The Guardian
A woman was taken into custody after throwing what she described as a shoe at Hillary Clinton during a Las Vegas speech.
The incident happened moments after Clinton took the stage Thursday at an Institute of Scrap Recycling Industries meeting at the Mandalay Bay hotel-casino.
Clinton ducked but did not appear to be hit by the object, and then joked about the incident....


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Though Chiropractic has been around for over 100 years, there are still many misconceptions about what chiropractic is and what a chiropractor does. This page is to help you learn more- and discover what we know- that chiropractic is one of American Healthcare's best kept secrets!
Some Myths About Chiropractic Care
Myth: Chiropractic manipulations are all high force with lots of twisting of the spine.
Truth: There are many methods that do NOT utilize twisting or high force to perform the manipulation. Wright Chiropractic, PA specializes in several techniques that are gentle enough for children and non-rotary in nature.
Myth: There is no medical basis for Chiropractic treatment.
Truth: Dr. Wright is a Doctor of Chiropractic and holds post-graduate certification as an extremity specialist. She regularly reviews research in Chiropractic advancements and applies it to her day-to-day practice. There's no smoke and mirrors.
Myth: Physicians and Chiropractors don't work together.
Truth: Dr. Wright works with many physicians and health care providers to coordinate patient care and provide regular updates throughout treatment.
Myth: Chiropractic treatment is the same for all patients.
Truth: Our patients are each individuals. Although the conditions being treated may have the same names, each patient can have different circumstances impacting their life. We create a treatment plan unique to each patient so each receives care that best meets their needs.
Myth: It's expensive to see a Chiropractor.
Truth: Chiropractic is one of the most cost efficient forms of healthcare in the USA. It is significantly less expensive to see a chiropractor than it is to have surgery, visit a pain management clinic, or stay on regular prescription drugs. The other important point is this: Care at Wright Chiropractic Health Center is oriented towards trying to provide tools for improved long-term stabilization and relief rather than simply just pain relief.
Myth: You get "addicted" to Chiropractic and have to keep coming back all your life.
Truth: Chiropractic is a training process for your body. Each visit builds on the next allowing your body to become more efficient and heal. While it is true that chiropractic care is similar to physical therapy in that you can't expect to "fix" your problem with one visit, seeing a chiropractor does not cause a dependency issue. In fact, most people choose to see a chiropractor regularly for preventative maintenance care once they take care of their initial complaint. Think of it like this: a regular chiropractic care patient gets to know what it feels like to have a healthy, mobile spine not tightened and inhibited by misalignments. Getting regular adjustments is like brushing your teeth and seeing your dentist regularly- it's a healthy habit that improves long-term health!
CLICK HERE to see our page on What to Expect on your First Visit!
READY TO SCHEDULE? Click the button below to do Online scheduling! We're ready to meet you!


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In a couple of hours I'm off to the airport and on my way to Christchurch. I'm sitting here right now with my mind (and stomach) absolutely churning with different thoughts and emotions: anticipation, excitement, nervousness, apprehension and a healthy dose of worry to round it all off.
Anticipation - I am so looking forward to all the amazing learning and networking and just know is going to take place over the next few days. I am also anticipating that it will be cold!
Excitement - "I'm going to ULearn...I',m going to ULearn..." Total geek out time, get to meet up with all my online friends - yay! I'm like a kid the night before Christmas.
Nervousness, Apprehension & Worry - I'm presenting...TWICE! I've made multiple back ups of my presentations, have spent countless computer hours creating them and have the sore elbow and stiff shoulders to prove it! I know I'm well prepared, I think my presentations are useful (and pretty - not that pretty is important...but I like pretty!), however; this still doesn't stop me worrying that something will go wrong, or I'll mess up, or I'll bore my audience.... all the usual paranoid and irrational thoughts that keep the adrenaline pumping. I've decided there are times where perfectionism is a bad thing. I'm also a bit anxious because I have to fly. I hate flying! I like going to new places, but I hate flying there. To add to my nerves there is supposed to be a storm front across half the country - nice!
My wiki to support my presentation & provide notes and further information can be found here.
So here I sit, full of expectations. I really need to close the lid on my 'puter and prepare to go offline for a while (that's an ask in itself - might have to divert Twitter to my phone...maybe not, imagine how fast the memory will fill up!) Rohi the Kea is ready for her trip down south, my bags are packed and guess what?
See you at ULearn08 everyone.


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I best start off with an apology to FunkiMunkiBadge lady Leah :( Just realised i have something here that i haven't posted yet! darn..it will be in the post tomorrow..*promise*
It's been one of those weeks..actually months. The one really good thing is we are off on holiday Saturday, and it also happens that our daughter will be ten on the same day. Are we off to somewhere exotic i hear you ask? Well that would be a big fat no. Not unless you call North Wales exotic...but regardless of the fact it doesn't involve a plane or half a dozen semi naked men running around waiting on me hand and foot..oh and yes i'm feeling nice so i would of chucked in half a dozen semi naked women running around for hubbys benefit too. I'm sure the holiday will be enjoyed.
We usually go on our holiday in school time but what with important exams and other such things we can't really take the children away from important classes this coming year.No matter how much money we would of saved doing so! The prices for breaks in the summer holidays are almost laughable, though i suppose it is classed as a luxury to have a holiday nowadays. Though personally i think it is more of a necessity.
I like to be away from everything and everyone i see day to day and just spend time with the family, exploring new places. Oh gawd i'm getting excited... roll on Saturday!
This week my smile moment was when i received some very yummy rumblers pots. I am a huge fan. I could easily have an addiction to them..i had Strawberry,Raspberry and Chocolate delivered. What more could a woman want? I just love the fact it's good for me and yet tastes divine. They are perfect for breakfast, a lunchbox or picnic.
You can follow them on twitter at @RumblersPots or check out their website here for stockists Rumblers
Anyway that's my lot tonight as i'm totally shattered.
Night Night X
Thursday, 14 July 2011
Well deserved holiday & Rumblers Pots
3 comments:
Have a lovely holiday! And don't worry about the parcel, I'd forgotten :) I don't know anything about Rumblers. xReplyDelete
- Anonymous18 July 2011 at 13:23
gorgeous blog!ReplyDelete
please visit my blog, would be an honour!
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Battlefield Hardline has spent its second week in pole position of the GfK Chart-Track All Formats Top 40.
Sales of EA's new shooter fell by 43 per cent week-on-week, but Hardline still beat this week's top new release, Sony's PS4-exclusive Bloodborne.
The hardcore RPG debuted at No.2, falling 22,500 units short of first place.
In third place is another new entry into the charts, Borderlands: The Handsome Collection a PS4 and Xbox One remaster of 2012's Borderlands 2 and last year's Pre-Sequel.
Grand Theft Auto V falls once place to No.4 as sales dip 11 per cent, while FIFA 15 remains steady in fifth position.
Retailer promotions help Call of Duty: Advanced Warfare and Far Cry 4 this week sales of the former rose 43 per cent, while the latter's sales shot up 233 per cent.
They weren't the only games to benefit from price activity, either. Sales of The Order 1886 rose 112 per cent thanks to retailer promotions, bringing it back to No.10.
And Minecraft: PlayStation Edition falls out of the Top 10 for the first time since February. In spite of a nine per cent rise in sales week-on-week, the PlayStation SKUs of the construction title drop from No.10 to 13th place. Minecraft: Xbox Edition sits in ninth place.
Below is the software Top 10 for the week ending March 28th:
1. Battlefield Hardline (EA)
2. Bloodborne (Sony)
3. Borderlands: The Handsome Collection (2K Games)
4. Grand Theft Auto V (Rockstar)
6. Dying Light (Warner Bros)
7. Call of Duty: Advanced Warfare (Activision Blizzard)
8. Far Cry 4 (Ubisoft)
9. Minecraft: Xbox Edition (Microsoft)
10. The Order 1886 (Sony)
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