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Improved consistency in drug response profiling with assay standardisation
FIMM researchers have demonstrated that it is possible to achieve good consistency between laboratories for drug response measurements by paying careful attention to the harmonisation of laboratory assays, and by using similar experimental and computational procedures.
In late 2013, a striking report was published in Nature, in which the authors cross-compared published data sets from the Broad and Sanger institutes in overlapping cancer cell lines. Their conclusion was that while gene expression profiles were consistent, drug sensitivity measurements showed highly discordant results. This study highlighted reproducibility issues in cancer pharmacogenomics, thereby echoing the recent concerns on the general lack of reproducibility of pre-clinical results, but at the same questioned the feasibility of functional profiling-based precision oncology.
Compelled to find out if this really is the case for all drug sensitivity measurements, a group of FIMM researchers started to compare the Sanger and Broad datasets against FIMM drug response data. They confirmed the poor consistency between the Broad and Sanger drug responses, but also observed a good level of consistency between the FIMM and Broad drug response results. The improved consistency originated from similarities in the assays, both experimental and computational procedures, and importantly, from using the same comparison setup.
These new results, published in Nature as Brief Communications Arising article today December 1st, show that it is possible to achieve good inter-laboratory concordance in drug response measurements.
"Even though we have seen very high reproducibility at FIMM in our high-throughput drug response profiling studies, it was important to show that also between-laboratory reproducibility is indeed achievable", commented Professor Tero Aittokallio from FIMM, the lead author of the study.
The results also indicate that the use of comparable laboratory and computational methods is critical for improved consistency.
"It will be important to develop global standards, similar to the MIAME standard for microarray data, not only for the laboratory assays but also for the computational procedures being used in drug data processing", continued John Patrick Mpindi, a bioinformatician who was responsible for the data analyses.
The comparative work by FIMM provides a more positive view on the reproducibility of drug response screening compared to some of the recent publications, and hence supports the potential of pharmacogenomics and precision medicine, provided that sufficient standardisation of drug sensitivity assays is achieved.
Original publication:
John Patrick Mpindi, Bhagwan Yadav, Päivi Östling, Prson Gautam, Disha Malani, Astrid Murumägi, Akira Hirasawa, Sara Kangaspeska, Krister Wennerberg, Olli Kallioniemi and Tero Aittokallio. Consistency in drug response profiling. Nature, Brief Communications Arising, doi:10.1038/nature20171
More information:
Professor Tero Aittokallio
Institute for Molecular Medicine Finland (FIMM)
University of Helsinki, Finland
Tel: +358 50 318 2426
Email: email@example.com
Further reading:
Tero Aittokallio's recent blog post
Haibe-Kains B, El-Hachem N, Birkbak NJ, Jin AC, Beck AH, Aerts HJ, Quackenbush J. Inconsistency in large pharmacogenomic studies. Nature. 2013 Dec 19;504(7480):389-93. doi: 10.1038/nature12831.
Cancer Cell Line Encyclopedia Consortium; Genomics of Drug Sensitivity in Cancer Consortium. Pharmacogenomic agreement between two cancer cell line data sets. Nature. 2015 Dec 3;528(7580):84-7. doi: 10.1038/nature15736.
Haverty PM, Lin E, Tan J, Yu Y, Lam B, Lianoglou S, Neve RM, Martin S, Settleman J, Yauch RL, Bourgon R. Reproducible pharmacogenomic profiling of cancer cell line panels. Nature. 2016 May 18;533(7603):333-7. doi: 10.1038/nature17987.
Yadav B, Pemovska T, Szwajda A, Kulesskiy E, Kontro M, Karjalainen R, Majumder MM, Malani D, Murumägi A, Knowles J, Porkka K, Heckman C, Kallioniemi O, Wennerberg K, Aittokallio T. Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies. Sci Rep. 2014 Jun 5;4:5193. doi: 10.1038/srep05193.
Collins FS, Tabak LA. Policy: NIH plans to enhance reproducibility. Nature 2014, 505: 612-613. doi: 10.1038/505612a


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Scarrport Serenade
Planning my campaign in Scarrport, which is a city on a delta where two rivers meet in the land of Kharvaire in Eberron.
We started playing and have gotten the party to The Den Mother, a local inn with an innkeeper with her finger on the pulse of Scarrport, or something like that. Players are getting used to their characters, trying to find the right "voice" and "attitude". GM is learning that it is hard to make the NPCs sound different… maybe trying to sound different when speaking for them might be better, how does one remember what type of voice to use so as to be consistent? Hmm. We meet again in a few days, trying to get used to uploading info from the last game and learn how much and when to award XP and Rewards.

subset: commoncrawl


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Yesterday I opined about why a TAB would be interested in the field of disability and assistive technology in particular. But that wasn't actually the original question. That inquiry was about access, which isn't quite the same thing.
Access is input and output. Which, if you really think about it, is the not the most important part of what a computer does for you, although it is the only parts addressed by assistive technology. The real value of computers is in the computing, the processing. The connection to the network is now key, but that is really just the connection to data, data which needs to be turned into information, and information that needs to be turned into meaning. Meaning itself takes different shapes or forms as it might be for learning and knowledge, entertainment, or facilitate the emotional connection to others. We really do not have a strong investment in how we interact with computers, at least not as compared to the value we place on the work they do. That we use a mouse and keyboard for input, and a screen for output is artifice. We haven't figured out how to do things a better way. Working in the field of assistive technology allows its practitioners more perspective into just how arbitrary our input/ouput systems are. I/O is not just arbitrary, it is fundamentally broken. I wish I knew how to fix things, surely that would make the world a better place, and make me quite wealthy! At least I can pontificate on some of the problems.
The screen doesn't seem to be too bad, we have happily enjoyed television for decades, and we are very visual beings by default. Computers, in contrast, excel at numbers, ultimately binary, which we use the screen to translate to words and window dressing for our convenience. The data is pure and easy to transform from pure states to arbitrary lines and curves that humans can visually associate meaning to. This is a hack though, it takes advantage of our capacity to digest visual information and to isolate key elements from a noisy environment. Rather than just output meaning, the computer display throws up a bunch of data on the screen with the expectation that the end-user will make sense of. The real work is left to the programmer or content provider. Things work out well enough, but it is not efficient. A 32 bit color display with a resolution of 1024 by 768 refreshing at 60 Hz pushes over 150 million bits per second. How much of that nine nine billion bits per minute does a human really process? How much does a person really need? Screen reader users are quite familiar with the imposition on them of linearizing a two dimensional system. It is almost amazing that things can work out as well as they do, but part of that success has to be because the computer output system is so absurdly wasteful already, loosing another order of magnitude for textual equivalents, is hardly a burden.
I regard the screen as less of a compromise than our chosen input method. A keyboard and mouse system was not designed for humans, we fell into its use by accident, and our inability to conceive of anything better. Again, it works okay, but who do you know that has three hands? If, based only on this critically important tool that humans construct for themselves, an alien race were to try to make inferences about features of the human body, what would they logically imagine? Fingers numerous and uniform like piano keys? A swath of tendrils or tentacles, one for each button? Surely humans have two sets of eyes, since, by design, efficient use requires close monitoring of both input and output systems, as the keyboard-mouse combination is simply too complex never to require visual (or tactile) exploration. Would humans really choose for themselves a device that required weeks and weeks of dedicated practice to develop the motor conditioning necessary for routine use? Would they allow themselves to be constrained to a layout routed in mechanical limitation decades after that constrainst was resolved?
Neither the keyboard nor monitor makes sense. Adding the mouse to the mix makes it more absurd. As assistive technologies, we know none of it is really necessary. Yet the best we can do is to emulate a keyboard, or add software to scrape the screen. I know I don't like it. I know it is holding us back. I just wish I knew of a better solution!
Wednesday, April 05, 2006
I/O, I/O, off to work I go!
Posted by Access Curmudgeon at 9:10 PM
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Tuesday, February 9, 2010
A 12-Step Program for Recovering Population-Deniers and Green Growth-Managers
You finally hit rock bottom—and you just can't seem to summon the stamina to climb out. But don't despair. Realizing that you are in trouble and are powerless to get out of it without assistance is the first step to recovery.
Once when you had control of your life you were an authentic environmentalist. You regarded the "IPAT" equation as axiomatic. That is, you accepted the fact that environmental impact (I) equalled the population level (P) times per capita consumption (A) times technology (T). But then you fell off the wagon, and in deference to political correctness you discreetly dropped the "P" and refused to acknowledge that population growth, and particularly immigrant-driven population growth was a key variable of environmental degradation. You could only think about one thing, "over-consumption", or another, "green technology". Until one day you woke in the gutter without a brain and without integrity, without everything that made you an intellectually independent being. You suddenly came to realize that your escapism and self-indulgent quest to feel good about yourself by making token "green" consumer choices only promoted more growth, and that growth of any kind was harmful. Oh, the guilt and the shame of it. You are ready to change but you just can't find the strength within yourself to make it happen. Where do you turn to? Whom do you turn to?
Friend, Sierra Clubbers Anonymous (SCA) is there for you. You are not alone. Other soft greens have also lost their way and lost their wits too. With their help, together you can locate that strength, that power that exists beyond yourself that you can draw on to effect and repair the damage you have done by your denial. At any time of day or night, at your weakest moment, when you feel that you must forfeit your new found courage and return to the soft but suffocating bosom of an environmental NGO and surrender your mind to Sierra Group Think---members of Sierra Clubbers Anonymous will be there for you to steady your faltering willpower and keep you to the path of redemption. If they are not immediately at your door they will be at the other end of telephone to guide your through you the darkness of despair back to a comprehensive understanding of the causes of environmental damage. Just when you were about to give up all hope of understanding why things are going to hell, SCA will come to your rescue. Change is possible.
But first you must admit to yourself that numbers matter, that it is not just about per capita consumption but the sum total of "capitas". You must acknowledge that would be pointless for a society to cut its per capita consumption in half only to turn around and double the population. And you must accept that there are no miracle technological solutions to what is essentially a moral problem—the need to stabilize and reduce our population level. By making things more efficient, new technology makes them cheaper, and therefore provokes even more consumption than before. More efficient use of scarce resources allows for and promotes more growth. You must finally grasp that smart growth is dumb. In short, you must make the decision to think for yourself and not swallow the filtered information of the Sierra Club executive or rely upon CBC Pravda for the facts. You must choose reality over delusion
As a signal of this commitment, you must pledge to follow the 12 steps to full recovery. They are,
Step 1: Honesty
After many years of denial, recovery can begin when with one simple admission of being powerless to regain your intellectual independence without reaching out for truth and that a self-righteous Sierran yuppie who is semi-literate in the laws of sustainability is more a fool than a so-called blue collar redneck who has no pretensions of superior consciousness.
Step 2: Faith
You must first have faith in biophysical laws and that the Commandment "Thou Shalt Not Trespass Carrying Capacity" trumps anything that Moses brought down from Mount Sinai or the optimism of the green apostles of false hope.
Step 3: Surrender
You must surrender your dependence on Sierra Club newsletters and set out on the lonely journey of educating yourself. You must start by understanding the exponential function and the limits to growth. You must understand that the world is finite as are its resources. No feat of human ingenuity can conjure up extinct species, replenish cheap oil or rehabilitate mined out soils without the use of fossil fuel-based fertilizers.
Step 4: Soul Searching
There is a saying in the 12-step programs that recovery is a process, not an event. The same can be said for this step -- more will surely be revealed. You must conduct a fearless moral inventory. Have any of your feel-good green gestures made a whit of difference? Did that solar panel you installed create more energy than was involved in making it? Did that so-called smart car you bought not involve an industrial process, was ore not mined , smelted and transported to a factory to rendezvous with rubber derived from fallen trees? Did not the so-called green factory it was made in consist of materials that inflicted a cost on the environment to make and transport? Were not the gains you made by riding a bike to work wiped out by taking that annual plane flight to Mexico or Bali? By siring or giving birth to two children did you not effectively double your ecological footprint and be responsible for more carbon emissions than a meat-eating man or woman without children could ever make up for? Are you not a hypocrite with your holier-than-thou green conscience?
Step 5: Integrity
Probably the most difficult of all the steps to face, Step 5 is also the one that provides the greatest opportunity for personal growth, the only kind that is benign. You must examine the financial reports of any environmental organization that you belong to and follow the money trail. You must renounce any group like the Sierra Club, Nature Conservancy or the David Suzuki Foundation which accepts corporate donations. You wouldn't accept your beloved NDP accepting such dirty money, so why is it acceptable for these groups to receive money from financial institutions and energy corporations? "Hear no evil, see no evil" is not the posture of anyone with integrity.
Step 6: Acceptance
The key to Step 6 is acceptance – accepting that you have been WILLFULLY ignorant and tolerant of corruption in the environmental movement. You must accept that you need an education. Start with Christine MacDonald's "Green Inc" which documents how much mainstream environmental organizations are on the corporate take. Then take a look at Canada and ask, why is the Royal Bank funding the David Suzuki Foundation and Nature Conservancy? Why is the Toronto Dominion Bank doing the same for the Sierra Club? What do they want in return? What are these green organizations doing, or more to the point, not doing and not saying to get that money? Why does Suzuki accuse climate change deniers of being shills for the petroleum industry while his foundation accepts donations from the natural gas giant Encana? Why haven't YOU being doing this homework? Why haven't YOU being asking these questions? Are not you the same kind of person who shakes his head when Christians in an evangelical church still support a minister who has been exposed for dishonesty, betrayal or adultery? Are you not a credulous dupe too?
Step 7: Humility
The spiritual focus of Step 7 is humility, realizing that your smug superiority complex is unwarranted. That the average logger or fish farm worker is no more responsible than you are for the system that we are trapped in.
Step 8: Willingness
Making a list of those that have been harmed by your support of false gods. The first casualty is the farmland we have lost to development fuelled by our having the highest population growth rate in the G8 group. And the many hundreds of species that are now at risk of extinction as a result. You must include on that list the fact that the environmental groups you blindly supported by their unwillingness to bite the corporate hand that feeds them have refused to fight population and economic growth and therefore made meeting Kyoto targets IMPOSSIBLE.
Step 9: Forgiveness
You must ask for the forgiveness of those you have slandered and race-baited, and from the constituency that you have betrayed by allowing them to think that your group was a watchdog guarding the environment. Your green "watchdog" stopped barking when corporate Canada fed him a bone.
Step 10: Maintenance
Nobody likes to admit to being wrong. But you must continually remind yourself that your blind obedience to a corrupt, money-grubbing corporate lackey for so many years demands your consistent apologies.
Step 11: Making Contact
You must make contact with reality and with knowledge that your organization and the editors of the politically correct rags that you read do not allow you to see. As the Romans said, "nullius verba"---take no one's word. Don't take their word or my word. Do your own research.
Step 12: Service
You can make amends for some of the damage that you have unwittingly done with your ill-informed good intentions by redirecting your donations and your efforts to projects and causes that make a difference. For example , instead of sending money or support to a nation like the Philippines that has no intention of controlling its population growth, re-deploy it to countries like Thailand or Madagascar that are serious about birth control programs. Money to nations like Ethiopia, Haiti, Afghanistan, the Philippines and the like essentially amounts to a birth incentive and too often a bounty on wildlife.
Finally, you must ask yourself, is your loyalty to an organization an informed loyalty to its ideas, policies principles or are you more loyal to the neighbours and friends in it? It is fundamentally a social club that you can't bear to challenge, is fellowship your main motive? If your allegiance is to the tribe and not the cause then you must ask, is a friendship that is contingent on your fixed opinions and organizational support more important than your integrity and intellectual growth? Are you too weak to stand alone? Is "getting along" by "going along" your survival code? If it is it, you are very human. And that is why we are in very big trouble.
Tim Murray . In your face and on your case. You gave me no quarter, so you shall receive none. With apologies to Diderot, the environment will never be safe until the last counterfeit environmentalist is strangled with the entrails of the last banker or developer.
6 comments:
- Nature Creek Farm said...
Great angry stuff here!
Thanks for saying lots of things I want to say but don't have the time.
You might like
"The banking mob, the insurance mob, and other criminally organized legislative muscle men, cartels and commodity syndicates, are all officially sanctioned as "interest groups" operating alongside hundreds of others in that whorehouse by the Potomac River.
To list just a few, there are environmental interest groups such as the Sierra Club, which exists so its officers can draw fat salaries and meet movie star environmentalists. There is an interest group for education, which exists to assure the mediocrity of our public schools."
http://www.freedomguerrilla.com also.
"My generation, The 13th (or Generation X) is the slim middle between two gluts of Useless. I keep hearing about how "tech savvy" the Millennials are, but this is like comparing a junkie to a pharmacist. Just because they're master users of technology doesn't mean they really understand fuck-all about how it works. And, no, texting really fast is not a marketable skill. The X'ers are stuck between two populations of entitled managers and now represent the harvesters of unintended consequences and the holders of the giant shitbag."
- February 13, 2010 at 9:00 AM
- Spirit Wolf said...
Hear, hear. Pretty much every big "charity" is a scam now, anyway, existing only to keep existing and their CEOs paid.
Political Correctness, and worship of the human (at least, the non-white one), is the rule of the day for all of them.
As for sending money to Somalia, HAH! The people causing all the trouble today, and "making babies starve" were the "starving babies" that were fed 20-25 years ago. Doesn't anyone see a cycle starting here?
- September 1, 2011 at 4:49 PM
- Jack said...
The ultimate "green technology" has been on the shelf for decades. It's called contraception, but it seems invisible to a lot of people.
- October 3, 2012 at 6:01 PM
- Nature Creek Farm said...
The problem with contraception as a mechanism for change is that it is missing the real problem. The number of humans is a problem now because the behaviors are consumptive. On this, I agree with Raj Patel: "The opposite of consumption is not frugality, it's generosity." If people are raised to be generous to their own future selves (producing usefulness rather than consuming resources as a rule), then they would be valuable and engaged in life, rather than a commodity to be "busied" with work, or to produce dozens of useless offspring. The population problem becomes a symptom of the lack of human moderation, not the main issue...though I'm sure there are still some fans of eugenics who will offer to choose who to keep and who to 'let go', thinking they know the direction of "progress" better than natural selection does.
- October 3, 2012 at 7:06 PM
- Michele Tittler said...
that was brilliant. And funny.
- February 11, 2013 at 2:21 PM
- Geo T said...
Sticking massive wind turbines like thumbtacks all over nice landscapes is another symptom of growthism denial. Wind power is perhaps the biggest land grab we've ever seen, with open space zoning laws overridden in closed-door meetings. It's a major symptom of the mental illness that poses as modern environmentalism. The media still insists that wind turbines are environmentally benign, but anyone with eyes, ears and a conscience can see that nature is being slowly forced into a few isolated pockets of pristine land, from which we'll still see wind turbines looming in the distance.
- April 11, 2015 at 11:45 PM


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The question-and-answer session was held, according to Betty Comoford, moderator of the event and vice president of MACC, because "there are a lot of questions and concerns about road closures for events during the season. We just want to make sure we are in compliance with the laws."
Lewiston is the venue for a car show in June as well as Timberfest in July, when Kneeland Street is closed to traffic. While many of the questions had to do with state roads (M-32 runs through Atlanta and Hillman), Connie Mallett, executive director of the Lewiston Area Chamber of Commerce, said she learned a lot from the panel.
"We've never been told that we need to go to the township (for a permit)," Mallett said in response to confirmation from Michigan Dept. of Transportation (MDOT) personnel that road closure permits must be obtained by local governmental units. She said in the past the Lewiston chamber has gone to the county road commission for a permit, not to the state.


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How nice is the word "nice"? Some would say, how quaint. Are you nice? Or is it an effort to be nice?
A small word for something that can go a long way. It seems that nowadays being nice is an extra effort for all of us. How can we be nice when prices are all going up? How can we be nice amidst traffic jams and city pollution? How can we be nice when we are suffering from being heart broken? How can we be nice, we're busy! …and all that jazz.
One day while I was eating at a famous fast food chain one of their crew was doing a survey. He went to different table to ask people some of their time and to no avail nobody said yes. Then he noticed me, that I was already finished eating, and ask me if he can conduct the survey. I said yes. He asked me things and stuff, it took us less than 5 minutes. Now dear reader, that was being nice. No effort needed! He did not ask me to do extraneous activities so why not say yes? He asks people when they're already done eating so why not say yes? The survey is no way near rocket science so why not say yes? Being nice is not an extra effort it is, actually, a natural thing.
As the survey ended he asked me to stay put and wait for my FREE dessert. Be nice.


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Two of my favourite AW-girls in a girl-girl action... That's something I can like..
The contrast of Cleo's darker skin and Larissa's creamy white skin is absolutely perfect. These two would be any man's (or woman's) deepest fantasy!!
Cleo looks like my ex girlfriend i love her videos beautiful and sexy
Love the scissor sisters picture.
Larissa, your pubic hair is gorgeous!
Muy bellas imagenes
Darf ich euch lecken


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The winner of the Verve stamp set of her choice for commenting is TannyP from All That Rubbish. Her comment was from Laurie's post.
If you're a winner, congrats!!! To claim your prize, please email Katrina at email@example.com and let her know you won, add your shipping address and we'll get your prize in the mail!
Thanks again to everyone who participated!


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Easy To Purchase And Purchase Viagra Via On-Line PharmacyTrying to decide if you should get insurance on your pet? There are of course professional's and con's to it. Years ago I decided to attempt it out. I believed, if something happened, it would be a great decision to have it. Some plans will cover basic vet treatment and heartworm and things like that. Read through the information beneath and make a decision for you and your beloved pets.
Make sure that you have chosen a pet medicine store that has secure mode of transaction for the clients to place their purchase. This is truly very essential. Another is examining out the options this kind of as lookup options for the prescription. We ought to have an simple search choice so that we can find out the 1 we look for. Some websites are so complex that wouldn't allow you to find the exact item you want. Check out the shop whether it is including well-liked brand and generic medications so that you can make sure that they are reliable and into severe company.
Norvasc is a popular and efficient hypertensive drug. It is prudent that you purchase the medicine from a trustworthy Canadian drugstore. You are assured that you are buying genuine products and you also enjoy fantastic savings.
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Heartgard Plus Chewables are beef flavored tablets for dogs and cats to treat and stop heartworms. This is a prescription drug which can be acquired only with a valid prescription from your vet. You can buy this medicine from a nearby pharmacy or can be bought on-line from a Canadian Online pharmacy or from an On-line pet meds store.


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MailChimp Tutorial, part 1. This article is for someone setting up a MailChimp account as a platform to deliver newsletters. Specifically, I am moving from another newsletter platform (GetResponse) to MailChimp. In this MailChimp tutorial #1, I will cover the steps of opening a MailChimp account (the free account). Then how to import current subscribers. In the […]
Home » import subscribers
MailChimp Tutorial #1 – Sign Up, Import Subscribers
April 8, 2017 by Helena Asmus Lim Leave a Comment
Filed Under: Email Marketing, WEB PUBLISHING Tagged With: automated newsletter, create list, import subscribers, mailchimp tutorial, rss newsletter


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You've no doubt read that climate models predict a 4°C rise in global temperature by the end of the century. "Incompatible with organized society" is usually how this threshold is described. Nobody can picture that clearly, it's so vague. But you do have clear images for the direction in which we're moving.
California wildfires and their smoke are this transition. Fire is part of any deciduous forest-to shrub-to grassland- to desert ecological transition.
There are two big picture components.
1. Short term, jet stream changes due to Arctic warming create ridging which dries out the Western US.
Researchers link western wildfire activity to arctic warming
... the amount of sea-ice found in the Arctic during the winter months is a driving force behind summertime weather conditions that control wildfire activity in the western United States during the summer.
In the case of western wildfires, the connection may be through a phenomenon called the "Arctic Amplification," whereby temperatures in the highest latitudes of the northern hemisphere are increasing at much faster rates than the global average.
The process then works through what climatologists call a "teleconnection," whereby what happens in one part of the world impacts the weather in other parts of the world. Atmospheric teleconnections are well-known, with one of the best examples being a reduction in Atlantic hurricane activity during strong El Nino years because El Nino is associated with increased high altitude winds over the Atlantic that tend to rip apart developing thunderstorms.
For wildfires, the connection is through the jet stream. Knapp and Soulé's research presents evidence showing that increased undulations in the summertime jet stream over the western United States create warmer and drier conditions that are conducive for wildfire activity. The specific term they use is "ridging," which means that the jet stream over the western United States bends northward. Under this northward bend extended periods of sinking air develop, which bring exceedingly warm and dry conditions.
They note there has been a 65 percent increase in the meridionality, or waviness, of the jet stream since the early 2000s, and this waviness causes the warmer and drier conditions. In turn, western wildfire activity has skyrocketed since 1980, ...
2. Long term (i.e. in about 85 years), we are moving toward a 4°C rise world where most of the US has become desert.
What the World Will Look Like 4°C Warmer Take a good look at their map.
Here's our piece of what the world will look like at 4°C rise.
The green area in Canada has arable conditions. Orange means desert. Red is underwater. Brown areas have been abandoned as uninhabitable. Where I'm typing this second, in Eastern Pennsylvania, will be abandoned in about 85 years. Here's the key.
The good news is that lots of that desert could be used for solar energy, if there were a civilization left capable of building it.
Since climate destabilization is nonlinear, we'll likely see staggered periods of slow change followed by very rapid degradation after tipping points. <sigh>
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What can debt-free, wealth-based, infrastructure funding be used for?
In addition to bridges and roads and the corresponding sewer systems:
- The Electrical Grid
- Green Energy
- Solar and Wind
- Fiber Optic Cable
- Energy Platforms
- Pipelines
- Geothermal
- Power Plants
- Airports
- Rail Transport
- Levies and Dams
- Ports
- Refineries
- Upgrades and Maintenance on the Above
- Personal Rapid Transit CHECK IT OUT
Each time we use this principal to fund infrastructure we spend inflation free, debt free money into the economy. In other words, we all get "richer". There is more money to go around and we live in a better society.
That's just the beginning.


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For anyone who remembers the N64 console, you know that it was extremely bulky and definitely not portable. A Bacman user who goes by the name 'Bungle' came up with a way to play your favorite N64 games on the go in a form that still personifies the original system.
This N64 mod is one of the smallest and most polished to date, and is in the form of a traditional N64 controller. The sleek, black gaming controller now has a screen in the center of its face and is surrounded by the control buttons. It can last for up to four hours of playing time.
The console is only a prototype at the moment, but the creator stated he will be making more for a profit soon.
Portable Gaming Controllers
More Stats +/-
Vintage Video Game Chocolates
Modernized Retro Console Designs
Vintage Game Controller Accessories
DIY Gaming Smartphone Mods
Touch Panel Motion Controllers


text: On Fri, Sep 29, 2000 at 02:06:33AM -0400, Barry A. Warsaw wrote: > > >>>>> "TM" == Trent Mick <email@example.com> writes: > > TM> I was playing with a different SourceForge project and I > TM> screwed up my CVSROOT (used Python's instead). Sorry SOrry! > > TM> How do I undo this cleanly? I could 'cvs remove' the > TM> README.txt file but that would still leave the top-level > TM> 'black/' turd right? Do the SourceForge admin guys have to > TM> manually kill the 'black' directory in the repository? > > One a directory's been added, it's nearly impossible to cleanly delete > it from CVS. If it's infected people's working directories, you're > really screwed, because even if the SF admins remove it from the > repository, it'll be a pain to clean up on the client side. Hopefully no client machines were infected. People would have to 'cvs co black' with the Python CVSROOT. I presume people are only doing either 'cvs co python'or 'cvs co distutils'. ...or is there some sort of 'cvs co *' type invocation that people could and were using? > > Probably best thing to do is make sure you "cvs rm" everything in the > directory and then just let "cvs up -P" remove the empty directory. > Everybody /is/ using -P (and -d) right? :) > I didn't know about -P, but I will use it now. For reference for others: -P Prune (remove) directories that are empty after being updated, on checkout, or update. Normally, an empty directory (one that is void of revision-conŁ trolled files) is left alone. Specifying -P will cause these directories to be silently removed from your checked-out sources. This does not remove the directory from the repository, only from your checked out copy. Note that this option is implied by the -r or -D options of checkout and export. Trent -- Trent Mick email@example.com


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10 sleeps until Christmas, the excitement is taking over!!
Today's gift was a huge surprise but is by far one of my favourites that I've received so far!
You all want to know what it is, don't you?
Today's gift was a full size 'Tattoo Me' eyeliner from Seventeen. Tattoo Me is a liquid eyeliner that promises 48 hour wear, and from some reviews I've read, it does deliver.
This eyeliner has a brush applicator that, from swatches on my hand, I can tell is quite firm and will make application easier. It's extremely pigmented, and I'm super impressed.
'Unrivaled staying power', you can say that again! The swatch I've had on my hand since 7am, is still on black as it was when I first swatched it. I've washed my hands numerous times, washed dishes, moisturised my hands and I've even just rubbed at the swatch, and it will not budge!
As I'm typing this, I'm using my Nivea Double Effects Eye Makeup remover to get it off my hand and it's come off really easily.
This eyeliner seems really good but it will definitely be one for parties/longer days where I need my eyeliner to last more than 8 hours or so. But for the time being I will stick with my Collection Extreme 24hr Felt Tip Liner, but I will get a lot of use out of this too.


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SOURCE: Sourcefire
July 10, 2012 09:00 ET
Leadership Position Secured Based on Completeness of Vision and Ability to Execute
Leadership Position Secured Based on Completeness of Vision and Ability to Execute
COLUMBIA, MD--(Marketwire - Jul 10, 2012) - Sourcefire, Inc. (NASDAQ: FIRE), a leader in intelligent cybersecurity solutions, today announced that Gartner, Inc. has positioned the company as a Leader in the "Magic Quadrant for Intrusion Prevention Systems."1
According to Gartner, "The network intrusion prevention system market is undergoing a period of dynamic evolution. Next-generation IPSs are available for the best protection, and first-generation IPSs are increasingly being absorbed by new next-generation firewall placements."
Sourcefire® pioneered NGIPS in 2003 when it delivered real-time contextual awareness, full-stack visibility and intelligent security automation to its customers. Sourcefire is also the only company to offer these capabilities with integrated application control.
The new report also highlights the company's high-performance FirePOWER™ platform and FireSIGHT® contextual awareness and automation, which are foundational to both Sourcefire's NGIPS and Next-Generation Firewall (NGFW).
Based on FirePOWER, Sourcefire NGIPS addresses enterprise requirements for flexible configurations, maximum protection, and faster processing of network data. FirePOWER acceleration technology provides market-leading performance with lower power consumption, allowing enterprises better threat detection and protection while maintaining a proven total cost of ownership (TCO). FirePOWER appliances' consistent and linear performance results make them a trusted solution for enterprise customers who need to scale their network security deployments with larger throughput models.
"After pioneering NGIPS, we continue to be committed to industry-leading innovation as we deliver on our vision of Agile Security. Our unparalleled ability to deliver visibility and control provides customers with true Information Superiority," said Martin Roesch, founder, CTO and interim CEO of Sourcefire. "We're very pleased that Gartner recognizes our execution and vision in the market as we continue to provide our NGIPS offering to our large enterprise and government organization customers."
To access a copy of the full report, compliments of Sourcefire, please visit http://www.sourcefire.com/IPSMQ.
About the Magic Quadrant
Gartner does not endorse any vendor, product or service depicted in its research publications, and does not advise technology users to select only those vendors with the highest ratings. Gartner research publications consist of the opinions of Gartner's research organization and should not be construed as statements of fact. Gartner disclaims all warranties, expressed or implied, with respect to this research, including any warranties of merchantability or fitness for a particular purpose.
About Sourcefire
Sourcefire, Inc. (NASDAQ: FIRE), a world leader in intelligent cybersecurity solutions, is transforming the way global large- to mid-size organizations and government agencies manage and minimize network security risks. With solutions from a next-generation network security platform to advanced malware protection, Sourcefire provides customers with Agile Security™ that is as dynamic as the real world it protects and the attackers against which it defends. Trusted for more than 10 years, Sourcefire has been consistently recognized for its innovation and industry leadership with numerous patents, world-class research, and award-winning technology. Today, the name Sourcefire has grown synonymous with innovation, security intelligence and agile end-to-end security protection. For more information about Sourcefire, please visit www.sourcefire.com.
Sourcefire, the Sourcefire logo, Snort, the Snort and Pig logo, ClamAV, FireAMP, FirePOWER, FireSIGHT and certain other trademarks and logos are trademarks or registered trademarks of Sourcefire, Inc. in the United States and other countries. Other company, product and service names may be trademarks or service marks of others.
1Gartner "Magic Quadrant for Intrusion Prevention Systems" by Greg Young, John Pescatore [5 July 2012].
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Sourcefire, Inc.
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Some Tips When Taking Meals to a Family in Need
I'm sure that at one time or another, most of us have taken a meal to a friend or family member or have been on the receiving end. It's something we all have in common. I thought I would share a few ideas to consider when taking a meal to another family.
1. Be sure to adhere to any dietary restrictions that the family might have.
Make sure you find out if any member of the family has any food allergies (dairy, shellfish, wheat, nuts...) and the plan your meal accordingly. When you take the time to prepare a meal for a friend the last thing you want to do is to make someone sick or worse, have them wind up in the hospital because you didn't know about a food allergy.
Also take into consideration any likes/dislikes or food preferences. If they have children, find out what types of food they like to eat as well. My friend Sarah is a vegetarian (although they do eat cheese and eggs), so I was especially careful to adhere to their dietary wishes.
2. Use disposable containers.
For the most part, we only take meals to friends during stressful times. Births, deaths and illnesses come to mind. Let's face it, while our friends are always thankful for the help, the last thing they want to do is to have to return bowls or casserole dishes to their rightful owners.
Do your friends a favor and use disposable containers. You can buy all different shapes/sizes of baking pans and food storage containers at the store. It gives people one less thing to worry about during an often difficult time.
Go on ahead and label each container too. Sometimes the person that you deliver the food to isn't the one who will actually be eating it. A clearly labeled container makes it easy for everyone to know what's inside.
3. Inquire about their freezer or cabinet space.
In addition to the meal that you are bringing, consider taking a little something extra for later on. This could be as simple as a casserole that they can put into their freezer. I like to take some homemade soup that I've canned using my pressure canner. The nice thing is that it doesn't take up any freezer space and has a very long shelf life.
4. Think about making something for breakfast.
In my friend's case, I knew that her husband would have to go back to work and that in the near-term, they would have people coming in to help care for Sarah and the boys. Mornings with two little kids can be stressful enough under the best circumstances let alone when the mom is trying to recover from brain surgery.
I decided that I would make some breakfast foods to alleviate some of the morning stress. Here are a few suggestions: Breakfast casserole, quiche, homemade granola, fresh fruit salad, banana or pumpkin bread/muffins, a jar of homemade jam or even pancakes or waffles. The possibilities are endless.
Here's a quick tip: For easy storage of the waffles/pancakes, store them in a ziplock bag. Take plastic wrap or waxed paper and lay it between the layers of waffles to prevent them from sticking together. The waffles can then be stored in the freezer and reheated in the toaster as desired. It's just like an Eggo waffle, only better because you made it from scratch.
5. It's snack time.
One other thing that you might not have thought of before is taking something to snack on. This would be especially nice for someone with children or new moms who need a little something while they nurse.
Again, talk to the family to see if they have any specific requests. A few possibilities: hummus and pita, homemade salsa and tortilla chips, fresh fruit salad, muffins, popcorn, even a box of their favorite crackers or granola bars... Just about anything will do.
I hope that you will utilize some of these suggestions the next time you take a meal to a friend. Not only will they appreciate it, but you will feel wonderful knowing that you were able to help out.
This post is part of Works For Me Wednesday over at We Are THAT Family. Pop by for some more handy tips.
4 comment(s). Leave yours!:
- Mary P said...
Good tips - thanks! I really like the one about snacks. After my baby was born many friends brought over wonderful dinners, but I mostly was interested in small snacks in between times :-)
- kathleen said...
So happy to hear your friend is home and recovering in familiar surroundings. I know your delicious meals will be greatly appreciated.
- SarahElisabeth said...
Useful ideas-love the idea of taking something for breakfast.
I try to label the food not only with the name of the dish but with warming up instructions and a full list of ingredients. Your first point about dietary restrictions is important but a full list of ingredients can also be reassuring.
you're a great friend, mrs. ha. am sure your friend appreciates your thoughtfulness and tasty food. great tips for others to consider as well.


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109476 Vita Spa Circuit BOARD, MAAX, MXBP2000, W-SPATOUCH
109476 BOARD, MAAX, MXBP2000, W-SPATOUCH MID-2014+. Used mostly on 500 & 700 Series Models. In 2014 There was a board change. Please compare your old board to this board to be sure. To be used only with the spa touch topside control.
This circuit board is a non-returnable electronic part. It cannot be returned or exchanged and so make sure it is the correct part. If you are unsure send us a picture of your part and we will identify the correct part.
This is a special-order part that will be coming directly from Vita By Maax Spas. Please allow 7-12 business days (excludes weekends and Holidays).
Click To Enlarge
- Item #: 109476


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- Home /
- Yeah Buddy Pre Workout By Ronnie Coleman Signature Series, Sour Berry, 30 Servings
Yeah Buddy By Ronnie Coleman Signature Series - 30 Servings - Sour Berry - Pre Workout
What Is Ronnie Coleman Yeah Buddy?
We named this product 'Yeah Buddy' after the infamous phrase that 8X Mr. Olympia Ronnie Coleman would scream during his legendary gym sessions to get fired up because that's Exactly what this product will do for you.
'Yeah Buddy' is formulated to give you the hard hitting extreme energy and focus that you need in order to power through your workouts so you can make gains!
Formulated with patented and clinically studied ingredients manufactured in the U.S.A.
- Extended Release Energy
- Only 1 Scoop Needed
- Non-Crash Formula
- Laser Focus
- cGMP Certified
- Manufactured in the U.S.A.
Key Ingredients In Yeah Buddy Pre Workout:
L-Citrulline & Agmatine Sulfate: L-Citrulline is converted to L-Arginine in the body, leading to increases in both L-Arginine and nitric oxide. Agmatine Inhibits Nitric Oxide Synthase (NOS), which is the breakdown of nitric oxide. Both ingredients act to Increase production of nitric oxide which promotes vascular dilation, which helps support normal oxygen and blood circulation throughout the body. *
Caffeine: Caffeine is about as tried and true as it gets in the energy department. Everyone is aware of the energy and focus benefits from caffeine but caffeine has also been proven in studies to increase athletic performance. Yeah Buddy contains a strong 420mg dose of both fast acting and extended release caffeine to avoid the dreaded pre workout crash.*
Beta-Alanine: Beta-Alanine is a pre-cursor to carnosine. It joins with the amino acid histidine through a peptide bond to form carnosine in the muscle. Muscle carnosine is the major buffering agent, or neutralizer, of hydronium ions that lead to muscle fatigue and failure. By increasing the amount of carnosine in the muscle, CarnoSyn beta-alanine both increases an athlete's peak performance and supports muscle recovery.*
TeaCrine: TeaCrine is a patent-pending compound containing pure theacrine, which can be found in natural sources such as the Camellia assamica varkucha tealeaf, coffee and certain exotic fruits. A nature-identical compound, TeaCrine delivers energy, mental clarity, and improved motivation and mood. It does not increase heart rate or blood pressure and is not a stimulant.*
What's In Ronnie Coleman Yeah Buddy Pre Workout?
How Do I Take Ronnie Coleman Yeah Buddy Pre Workout?
As a dietary supplement, mix 1 scoop of Yeah Buddy in 8-12 oz of water. To assess tolerance on first use mix 1/2 scoop with 4-6 oz of water. Do not exceed daily recommended dose of 1 scoop. Use in conjunction with a proper diet and exercise regimen to maximize results.
Keep Out Of Reach Of Children. Not intended for use by persons under the age of 18. Do not exceed recommended dose. Contains caffeine.
PLEASE NOTE: Product image is representative of the product offered but may not have the exact attributes. Please read product description for the specific attributes of this product.
PLEASE NOTE: The information above is intended for reference only. While we attempt to keep our information accurate, we cannot guarantee it is an accurate representation of the latest formulation of the product. If you have any concerns, please visit the vendor's web site. The information above are the views of the product's manufacturer, not the views of Same Day Supplements. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
*Prices are subject to change at any time and some items are limited to stock on hand.
|Ronnie Coleman Signature Series
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I loved all the layers on this sketch, and decided to put some of my favourite dies to work. I know the WMS girls are devoted to their Spellbinders, and for good reason! But I am just LOVING my PTI dies... and they're very cost effective, which is always a plus for me!
I am still exploring the catalogue of Papertrey goodies, but have you ever met another cardstock so delicious? I didn't think so... I love how crisp that little WMS sentiment comes out on the PTI white. So clean and sharp!
Hey, did you know there was such a thing as Martha Stewart seam binding? Me neither... imagine how quick I snapped up the ones I found in a clearance bin at Michael's. I have never actually looked to see if they were just old colours, or if she no longer makes it? But I loved this Kraft coloured one...
One more thing... I found this challenge, Totally Hues, and just had to play along with this week's amazing bright colours! Take a look:
I found these really cute little stamps at my LSS awhile back, and actually let my daughter play with them first... she is so adorable when she stamps! Anyway, when she stamped this little popsicle (over and over and over... a DP Designer in the making!), I knew I couldn't wait to colour it:
Now this is SO not my usual style. There's nothing vintage or shabby or pretty about it. It's just so SUMMER. I love the bright colours, and will have to dream up a fun gift to attach this little tag to. I will for sure be joining Heather and her challenge again!!
Paper: PTI Spring Moss, Scarlet Jewel, Ocean Tides, Kraft, White
Stamps: PTI Tag Its #1, Waltzingmouse Say it with Style
Ink: Stampin' Up Baja Breeze, Rich Razzleberry
Other: Martha Stewart Seam Binding, Papertrey Ink Dies
Paper: PTI Summer Sunrise, White
Stamps: Studio G (I think), PTI Fillable Frams #9
Ink: VersaFine Onyx
Other: Papertrey Ink Dies, Vintage Button and Ribbon from stash, Copic Markers
Pin It


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Demonising Justin Gatlin
13th September 2015
Wellington Saints basketball player Jordan Mills has been banned from all sport for 12 months after testing positive for prohibited asthma medication terbutaline (otherwise known as Bricanyl). The Sports Tribunal of New Zealand today released their decision after Mr Mills returned a positive test after a National Basketball League (NBL) match on 19 May, 2017.
In the hearing earlier this week Mr Mills promptly admitted intermittently using the inhaler, which contained a prohibited substance, for an ongoing asthma condition. Despite attending Drug Free Sport New Zealand (DFSNZ) education seminars, one as recently as March 2017, Mr Mills was unaware that the medication was prohibited.
Terbutaline is a Beta-2 Agonist which is prohibited at all times on the 2017 Prohibited List. It is used to treat asthma and other pulmonary illnesses, but it also could enhance an athlete's sports performance. Although Mr Mills is disappointed at the situation he is in, he accepts that the ban is a result of his failure to personally check that his medication was permitted under the WADA Code.
"It wasn't good enough that I simply relied on my doctors to ensure that any medications I was prescribed were permitted under the WADA Code," Mr Mills says. "I should have personally checked my medications and had I done that, I would have known I needed a TUE or to use a different asthma medication. It's disappointing, and I think unfair, that I end up with a ban for legitimate asthma medication longer than many athletes who test positive for illegal substances such as marijuana, but I guess that highlights the importance of checking these things yourself and not relying on others or assuming things will be okay."
DFSNZ chief executive Nick Paterson agrees that it's disappointing when an athlete who was not intentionally doping is banned from sport for not doing the basics expected of someone competing in a national competition. "Mr Mills should have known better, having attended an anti-doping education seminar earlier this year and having competed in the NBL for a number of years in New Zealand. He has been tested before and knows about the resources available to him.
"Our role at DFSNZ is to uphold the World Anti-Doping Code, and athletes and their support personnel need to do their part too, fulfilling their responsibility to check every year whether or not their medication is permitted in sport. The majority of these inadvertent cases over the past few years demonstrates that we need to continue to work closely with National Sports Organisations in providing education for their athletes to help them understand their anti-doping responsibilities," Mr Paterson says.
DFSNZ provides anti-doping seminars to NBL teams and players annually and all DFSNZ resources available at these seminars specifically mention terbutaline as a banned substance in and out of competition. Athletes are required to apply for a TUE to use prohibited substances, if no other alternative medication is available.
The one-year ban has been backdated to the day of the sample collection on 19 May 2017, due to Mr Mills' prompt admission. Read the decision of the Sports Tribunal of New Zealand here.
• This media release was originally published by Drug Free Sport New Zealand (DFSNZ) on 10 November 2017. To access the original, please click here.
The World Anti-Doping Agency (WADA) has been blocked from completing its mission to extract data...
The Rodchenkov Anti-Doping Act (RADA) has been introduced into the US Senate, after being introduced...
Ten athletes have been cleared to represent new countries since the last update from the...


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Lipstick of the day #17 - Chanel Rouge Coco Shine in Flirt #69 Spring 2012
Tuesday, 31 January 2012 | 9 Comments
Rouge Coco Shine in Flirt #69* is my cup of tea...because it's coral! I have a couple of Rouge Coco Shines and I love the formula - they are great for days when full on traditional lipstick is just a bit too much.
I picked out some similar colours I have for comparison. I've always thought Liberté was quite bright and orange, but next to Flirt, it looks quite muted.
The Rouge Coco Shine formula is very soft and therefore the lipstick itself is quite delicate. The edges were already "chipped" before I had even touched it...I simply wounded it a couple of times to have a look at the colour and to photograph it.
Like other Rouge Coco Shines, Flirt is sheer with subtle shimmers. In my swatch below it is pretty much a mix between Rivage (pink) and Liberté (peach). Due to the sheerness of Rouge Coco Shine, how the colour will look on your lips depends on how pigmented they are.
I have to say Flirt is probably my favourite Rouge Coco Shine lipstick. But then I am biased towards anything coral.
p.s. I wore Flirt with Blush Horizon de Chanel & Eclosion quad (review coming soon) and they match wonderfully.
*Sorry I am incredibly childish but I find it funny that Flirt is #69


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Hotel Medium Valencia3 Share Tweet
This affordable design hotel is positioned just across the road from Valencia's City of Arts and Sciences. Planning to visit? Request for the room with a balcony that faces the historic city centre for amazing night views!
Hotel has a very stylish interior, it renovated in 2009. It is sort of affordable boutique hotel.
They hired some local photographer to photograph all the around the city and then made photos of different size, framed with completely different frames and positioned on the walls with no particular order or scheme. That guy really had a Lomographic eye for the pictures.
The location of the hotel provides easy access both to the historic city centre and to the City of Arts and Sciences (ask for the room with the balcony which is facing it! incredible views at night!).
Hotel has 105 rooms, 1 bar and 1 restaurant. It is just 46 euros a night for both single or double room. Free wifi all around!
Food is not really good and be aware of siestas (no food during the day), and no food after 10 pm as well.
But I guess it is everywhere in Spain. Head to one of the shops across the road to stock yourself with bocadillas.
Address is:
Hotel Medium Valencia
General Urrutia, 48
46013 – Valencia, Spain
Phone: +34963347800
Fax: +34963347801
written by neja on 2010-06-23 #places #food #hotel #spain #restaurant #location #valencia #medium #affordable #boutique-hotel #wifi


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Still A Long Way To Go For Anti-Counterfeiting Trade Agreement - http://bit.ly/nbbeYH good summary of where things stand #acta
pic of the week : Leadenhall Market - http://bit.ly/qBRUDP gorgeous #london #pix #flickr
Project Biped - http://bit.ly/oryWpH #openhardware project to produce dynamically-balanced bipedal #robot using 3d printer
France gets A+ from the US for its anti-consumer intellectual property related policies - http://bit.ly/orgmuF French citizens can get lost
Fujian fish drop dead in biblical proportions - http://bit.ly/qHtvHC eek #china
Photographs Are Mechanical Representations Of Facts, And Thus Should Have Only Thin Copyright Protection - http://bit.ly/qVjYw1 interesting
U.S. measures to reduce teenage smoking deemed WTO violation - http://bit.ly/nrLBdF #WTO is a disgrace - time to abolish it
Cablegate: #Microsoft Asks US Government to Help Derail Vietnam's Migration to GNU/#Linux - http://bit.ly/ox82j9 truly shabby behaviour
#Apple sees Galaxy #Tab ban upheld in Germany over #Samsung patent lawsuit - http://tnw.co/pMjAg2 in notoriously patent-friendly court
Cablegate: "42% of Argentine Firms Use #Linux on at Least Some of Their Computers" - http://bit.ly/n5PWar v interesting stat #argentina
UK bookseller Waterstone's to launch a Kindle competitor - http://tnw.co/oOQZKP will it be #android based? #ebooks
Murdoch's News International reportedly launching new online publication in the UK - http://tnw.co/owkd9y but will they call it Delphi 2.0?
Extension of #Copyright term for Sound Recordings in EU - http://bit.ly/ps2vGv good summary of a disgraceful, unjustifiable move #monopolies
UK promises #transparency at home whilst fighting it in Brussels - http://bit.ly/pVidJB hypocrisy, thy name is Dave (& Nick)
Government of Castile-La Mancha to drive free software innovation within MORFEO community - http://bit.ly/peMvpL #opensource moves in #spain
#Oracle v. #Google - Google's Expert Report - http://bit.ly/npic9H "I disagree with Prof. Mitchell's conclusion"; no surprise...
Kernel comment: The obstacle course of cooperation - http://bit.ly/rrcfER raises important issues #linux #wifi
#Patent Reform Passes the Senate with Teeth, Heart Missing - http://rww.to/nqvHw3 don't expect a brain, either...
Bliar: How Much Death Can One Man Want? - http://bit.ly/o2z9yg go on, tell us what you really feel... #iraq #iran #torture
Practical Tips For Piratenpartei Berlin - http://bit.ly/neMVmu "chance of success in the election has now climbed from 90% to 99%." #germany
Innovation & OpenStack: Lessons from HTTP - http://bit.ly/raphl4 I don't get this: surely building on AWS APIs hands control to Amazon?
"An Extreme Rainfall Event Unprecedented in Recorded History Has Hit the Binghamton, New York Area" - http://bit.ly/qkMkN6 extreme enough?
EU Consultation on scientific information in digital age - http://bit.ly/nCgRI6 closes today: pl. do this now - only takes 5' online #openaccess
Proposal for a WTO Agreement on the Supply of Knowledge as a Public Good - http://bit.ly/nVgQkl now that's an idea
In a Bold Move Towards Accountability, Road Casualty Data Published Online in UK - http://rww.to/pMeh6Y kudos to all involved #opendata
UK Police attempting to criminalise investigative #journalism - http://bit.ly/o3niZc very bad trend
#RIAA Sending #DMCA Takedowns On FREE Music Being Distributed Directly Off Universal Website & Promoted By Artist – http://bit.ly/ndnWrP
Arduino ADK spices up phones - http://bit.ly/o26sQG very cool: #arduino meets #android
#Patents Directed to Human Organisms - http://bit.ly/nSKu6W the makings of another mess?


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Friday, August 15, 2014
Portlaoise Prison - Wikipedia, the free encyclopedia
Portlaoise Prison - Wikipedia, the free encyclopediaTom Hoare strongly criticized conditions within the prison stating that staff were forced by senior management in the prison to use excessive force against prisoners. He also criticized the then Governor of Portlaoise Prison, William Reilly, and the Minister of Justice Michael Noonan stating "I accuse the minister of negligence in this area. I accuse the management of Portlaoise Prison of being indifferent to complaints. I would hate to be a prisoner making a complaint".[6] At the Prison Officers Association 1984 conference a delegate from Portlaoise Prison, Larry O'Neill, told the conference: "If Hitler wanted generals today he would find plenty of them in Portlaoise. After the war the Nazis said many of them were doing their duty and that is what the management in Portlaoise are saying today".[7]?
Posted by encourage change at 9:28 AM
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- paddoconnell said...
- December 21, 2016 at 2:09 PM
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|Wilhelmina (Wilhelmina Helena Pauline Marie of Orange-Nassau; August 31, 1880 – November 28, 1962) was queen regnant of the Kingdom of the Netherlands from 1890 to 1948 and Queen Mother (with the title of Princess) from 1948 to 1962. She ruled the Netherlands for fifty-eight years, longer than any other Dutch monarch. Her reign saw many turning points in both Dutch and world history: World War I and World War II, the Great Crisis of 1933, as well as the decline of the Netherlands as a major colonial empire. Outside the Netherlands she is primarily remembered for her role in the Second World War, in which she proved to be a great inspiration to the Dutch resistance, as well as a prominent leader of the Dutch government in exile.[1]
Tactful, and careful to operate within the limitations of what was expected by the Dutch people and their elected representatives, the strong-willed Wilhelmina became a forceful personality who spoke and acted her mind. These qualities showed up early on in her reign when, at the age of 20, Queen Wilhelmina ordered a Dutch warship to South Africa to rescue Paul Kruger, the embattled President of the Transvaal. For this, Wilhelmina gained international stature and earned the respect and admiration of people all over the world. Wilhelmina had a stern dislike of Great Britain, which had annexed the republics of Transvaal and Orange Free State in the Boer War. The Boers were descendants of early Dutch colonists, with whom Wilhelmina felt very closely linked.
Queen Wilhelmina also had a keen understanding of business matters and her investments made her the world's richest woman, a title retained by her daughter and granddaughter, Beatrix. The Dutch Royal Family is still reputed to be the single largest shareholder of Royal Dutch Shell.
Prior to the outbreak of the First World War, a young Wilhelmina visited the powerful Kaiser Wilhelm II of Germany, who boasted to the Queen of a relatively small country, "my guards are seven feet tall and yours are only shoulder-high to them". Wilhelmina smiled politely and replied, "Quite true, Your Majesty, your guards are seven feet tall. But when we open our dikes, the water is ten feet deep!".[2]
|Although membership of the Order was opened to Americans only in 1927, it is a measure of that country's influential standing that by the 1940s the American Cardinal Spellman held the post of 'Grand Protector' within the Order, whereas King Leopold of Belgium and Queen Wilhelmina of Holland were mere 'protectors' within their respective countries!
|Korte geschiedenis van de Orde
Rang van Grootkruis van Eer en Devotie van de Nederlandse Afdeling van de SMH Orde van Malta (tot 1970)
(Rank of Grand Cross of Honor and Devotion of the Dutch branch of the SMHOM (until 1970))
1911 J.J.G. baron van Voorst tot Voorst, Baljuw, Voorzitter 1911-1931
1911 H.M. Koningin Wilhelmina
1911 Z.K.H. Prins Hendrik, Hertog van Mecklenburg, Baljuw
1931 Mr E.O.J.M. baron van Hövell van Wezeveld en Westerflier, Baljuw, Voorzitter 1931-1936
1936 L.F.J.M. baron van Voorst tot Voorst, Baljuw, Voorzitter 1936-1939
1943 Z.T.J.F. baron van Dorth tot Medler, Baljuw, Voorzitter 1942-1953, Wnd Voorzitter 1939-1942
1946 Zijne eminentie dr J Kardinaal de Jong, Baljuw
1949 S.K.H. Prins Bernhard, Prins van Lippe Biesterfeld, Baljuw
1952 Mr E.H.J. baron van Voorst tot Voorst, Baljuw, Voorzitter 1953-1964
1952 Ir J.B.G.M. ridder de van der Schueren, Baljuw, Kanselier, Voorzitter 1964-1970
1953 Mr E.L.M.H. baron Speyart van Woerden, Coadjutor, Baljuw
1960 Zijne Eminentie dr B. Kardinaal Alfrink, Aartsbisschop, Baljuw, Grootkruis van Magistrale Gratie
1960 H.K.H. Beatrix, Prinses der Nederlanden, (>1980; H.M. de Koningin)
1970 Mr E.T.M. baron van Voorst tot Voorst, Baljuw, Voorzitter 1970-1992
http://www.maltezerorde.nl/gesch_rang_grootkruis.htm (Proof Positive)


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This is a fairly short blog because it has one important message to McDonalds – "we have heard of your name, we know how to recognise a McDonalds, you do not have to stick large McDonalds billboards everywhere". Dear reader, the reason for this rant will become clear in a short while.
The plan for our last two weeks is to head north to Monument Valley, then further north to the Arches National Park at Moab, a long loop westwards to Bryce Canyon National Park, then south to Zion National Park Park and finally further south west to Las Vegas for our last few days in the USA this trip before we head to LA to fly home.
There are two possible routes to Monument Valley from Winslow, one is to drive to Flagstaff, the other is to head north through Navajo country and the Hopi Tribal Lands – this latter choice is the one we have made because the area is known as Arizona's High Country, it is isolated and empty but for a few small villages and towns.
And so we set off north on a quiet country back road. Typical of the views we see is
Mesa of amazing size standing in isolation
abandoned houses from an earlier age
empty countryside
craggy countryside
and then,peeping over the horizon in an area where no one lives, at a crossroads
is a large McDonalds sign telling us that the nearest McDonalds is about 90 miles away and the next one after that is about 120 miles away.
Do they really need to warn us this far in advance?
To be fair to McDonalds, on the other side of the crossroads is an advert for Cellular One but at least their shop is in the next town.
Three hours later, having passed both McDonalds advertised on the billboard, we get our first view of Monument Valley.
Apart from the odd section of road (and certain billboards), it was a lovely drive through some wonderful countryside.


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Among the images that come to mind when we think of our nation's birthday celebrations are barbecues. Alas, for many of us living in New York City, grilling is something we believe is only possible if you live in the suburbs or have a yard. Fortunately, there are options for us apartment-bound, city folk. From portable to electric grills, there are devices to put some sear and smoke on that meat for the Fourth of July weekend. Here's a guide:
Fold it
Carry the Ascot Portable Charcoal Grill from Brookstone to the park for a gathering with friends and family and later fold it flat for easy storage when not needed. At $54, this baby won't break the bank.
Hang it on the railing
This little grill is ingenious—albeit slightly worrisome! Like a flower box that hangs onto a balcony railing, this hot item can be hooked onto a railing or wall. When not in use, you can use the BBQ Bruce Handrail Grill as a flowerpot. Now that's a double duty gadget.
Go electric
In New York City "it's illegal to store a standard backyard propane barbecue on a balcony, roof deck, roof, rear yard or courtyard." One option is to use electrical grills. This nifty Weber grill is small and could be used with a rolling cart to raise it off the floor, making it more comfortable for the cook.
Charcoal it up
If you ask us, charcoal grilled meat is the best out there and according to New York City fire codes, cooking on a charcoal grill is allowed on terraces or rooftops as long as there's a 10-foot clearance between the building and grill and you have access to a water source or a fire extinguisher. The STŌK™ Drum Charcoal Grill is not only small but with its handsome orange cover also cute as a button.
Get Infrared
Infrared is the microwave of the grilling world. These cooking devices heat up faster than conventional grills and produce higher temperatures, in turn cooking your meat faster than other outdoor cooking methods. At $400, the 20-lb Solaire Gas Grills Go Anywhere 304 Grade Stainless Steel Portable Infrared Propane Gas Grill is by no means considered cheap but a pretty good deal as far as infrareds go.


text: Hallmark: $5 off $5 Purchase CouponDecember 3, 2010 This post may contain a link to an affiliate. See my disclosure policy for more information. Hallmark is offering up a new $5/$5 purchase printable coupon! It's valid today, 12/3 through 12/5. You can use it on almost everything (greeting cards, wrapping paper, etc.)!


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5 Things About IF Participant Richard Ewing
Hi guys!! Illustration Friday ARTISTS is a new series highlighting YOU — the IF Participants. We are randomly emailing out mini-interview questions. You could be next — watch your inbox! Welcome to your art community! :)
Name: Richard Ewing
Website: carickature.blogspot.com
Location: California
Fave IF Topic you've illustrated:
This was a very difficult choice. Over the past years there have been many enjoyable challenges and images. I find that, at times, the word prompt is a lot of fun to conceptualize around and opine to but the resulting art may end up just fair to middlin'. Conversely, I've occasionally read a new week's word and thought –I'll not get much out of this stupid word — and then found that the finished illustration is one of my favorites. Odd how that works.
Having to select just one I think I'll go with a more recent one from last month: TEACHER.
When I'm not illustrating I'm teaching art at a couple of colleges, so this was right down my alley. I approach each IF prompt by finding a known personage to caricature, and this week's victim was Severus Snape.
5 Questions:
1. What is something you would like to learn to do?
When I set out to participate in Illustration Friday I had two goals in mind.
One was to experiment visually with wild abandon — self directed. (and to master these explorations)
Secondly, I wanted to increase my speed in completing finished art.
These are still my goals, so in a nutshell I'd say I am teaching myself to shorten the time it takes to do an image, while increasing the professionality and polish of the finished art.
2. What's your most-used art tool?
The Paintbrush. Most of my inking and paintwork is done with a round or flat.
3. 3 things that inspire you (yes, only 3):
1) Looking at drawings and paintings that push the edge form-wise, application-wise, and compositionally. If it bends my eye, then I want wallow in it.
2) Studying the creative arc of all artists, ranging from musicians, illustrators, writers, actors etc. I delve into their peaks and valleys and try to understand why or how they arrived at any particular point or level. This is sometimes more revealing than the art they create. It's all about process.
3) Other friends and colleagues who are busy doing THEIR art. I like to have others around to ping my pong…. uh, so to speak.
4. What are you looking forward to?
My next cup of coffee… and then on a larger horizon, having more time to solely do illustration projects and the like… I just want to paint and draw pictures… and ride my bike.
5. Tell us something random about yourself.
My favorite color is Violet …but not purple.
*Thanks Richard!
Richard has been participating in IF for 122 weeks in a row!! Amazing! Check out his work!
More art inspiration!
Thomas James
Latest posts by Thomas James (see all)
- Winning Illustration for WALL by ValeXn - January 11, 2019
- Winning Illustration for GAME by Dave Murray - January 7, 2019
- Winning Illustration for WINTER by Marian Blair - December 28, 2018
Posted by Thomas James on 09/21/12 under artists
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Manchester United swept aside title rivals Arsenal 3-1 at Emirates Stadium to move within a point of leaders Chelsea.
Nani opened the scoring in the 33rd minute when his chip across goal was palmed in by Arsenal goalkeeper Manuel Almunia, before in-form England striker Wayne Rooney swept home a second following a quick counter attack.
A third on the break from Park Ji-Sung at the start of the second half effectively ended the contest, although defender Thomas Vermaelen netted a consolation for the out-muscled Gunners.
Arsenal, who had started the match five points behind Chelsea ahead of their trip to Stamford Bridge next weekend, began well as Andrey Arshavin got away down the left, before cutting inside and trying to curl the ball past Edwin van der Sar from a tight angle, but his shot drifted wide.
United, though, were quick to regain possession and then cut down any space for the home side.
Nani and Darren Fletcher combined as they almost played in Rooney, but William Gallas made an important blocking tackle in the six-yard box.
Alex Song - back from the African Nations Cup - then had to hack the ball clear at the far post as United again got clear down the right far too easily.
When Arshavin - who was ineligible for last season's Champions League semi-final clash between the sides - burst away again, he lacked any support in the middle.
The Russian, though, remained Arsenal's most potent attacking threat.
In the 13th minute he skipped away down the left, cut back inside Wes Brown and curled another effort goalwards, which this time was only just wide of the far post.
Arsenal captain Cesc Fabregas suddenly burst into life with a surging run down the middle, before slipping in Arshavin, but the Russian lost his footing at the key moment and United cleared.
United - who have played a match more than Chelsea - slowly started to gain the upper hand and Gallas needed to make another timely tackle in the penalty area as Paul Scholes shaped to shot.
Nani drilled the ball wide as Arsenal were again exposed in the right channel, before playing a key part in the goal which gave United the lead.
The winger skipped easily in between two defenders then chipping the ball back across goal. Almunia pushed it inside his far post, with Park Ji-Sung ready to tap the ball into the net.
Fabregas' shot following a corner was blocked - and four minutes later United were 2-0 ahead.
Again Nani was the provider, dashing clear after picking the ball up from Rooney before squaring it for the England striker to sweep home his 22nd goal of the season, low into the corner.
The Gunners faced an uphill battle to get back into the match, with Arshavin firing wide from just inside the box - as manager Arsene Wenger was left to scratch his head and looked to the heavens for inspiration.
It could have been worse on 41 minutes, but Nani blazed his shot wide after more good work from Rooney down the left.
There was a hold-up at the start of the second half as Rooney received treatment following a knock on the knee in a challenge with Bacary Sagna.
The England forward, though, was soon back in the action, and tested Almunia with a fierce angled drive after cutting in from the left.
It was game over on 52 minutes, when United scored a third following another simple counter.
This time is was Park who broke clear, sprinting onto Fletcher's chip into the Arsenal half and then slotting past Almunia from just inside the box.
The Gunners were also well beaten here 3-0 by Chelsea at the end of November, before a run of seven wins from nine hauled them back into title contention.
Fabregas, continued to drive his young team on, firing over and then just too close to van der Sar, then Song volleyed wide.
Theo Walcott came on as substitute - and Arsenal pulled a goal back with 11 minutes to go when Vermaelen's volley took a deflection off Jonny Evans to wrong-foot van der Sar.
However, there was to be no grand finale as Wenger's youngsters were again found wanting when it mattered most.


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The percentages of these states' populations that are non-Hispanic white are 94%, 83%, 71%, 82%, and 75%, respectively. Compare that to the 63% of the country as a whole that is non-Hispanic white and we see that the putative problem of "White privilege" is something whites treat more seriously than non-whites do.
While I'm partial to Z-Man's Cloud People/Dirt People distinction on account of my childhood fondness for 16-bit role playing games, the Derb, who has long used the Goodwhite/Badwhite distinction, underscores the intra-racial nature of America's great cultural divide:
Nobody's passions are stirred by thinking about other races in the aggregate. What gets our juices flowing is thinking about our own status ranking among people of our own race. That's what supplies the driving energy, the will to combat, in the Cold Civil War: How do other white people see me? No white person gives a fig about how blacks see him. Who cares what blacks think?To "No white person" it might be added "who thinks systematically about meta issues involving race"--I've come across plenty of white proles who care far too much about what blacks think about them--but that's a tangential quibble with an important observation.


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If you already have a Gamer Launch account connect your Facebook account on your user profile first before using Facebook connect to login. Otherwise you may end up with a new account.
Fridays and Saturdays are open for guild members to suggest events through an officer All events are set to game time to avoid any conflicting time zone confusion.
We accept all classes and roles, although raiding spaces are limited. Information regarding upcoming raids can be found in the in-game calendar.
The guild is exclusive to over-20s. Applications from members under the age of 20 will not be accepted at this time.
The Golden and Silver Axes are helpful, experienced players who are available to help guild members where needed. Please be considerate and remember that we want to play the game too!
The KMA officers (Golden Axes) are Asham (Ash), Anghmar (Rickard), Daegaroth (Jonah), Phantom (Mitch), Bhlokw(Michiel), Raiju (Heddy), Gyir (Jana), Rinusch (Marinus) Yrsela and Twigged (Elias).
Should you have any guild-related queries, whisper a Golden or Silver Axe in-game or use the website's PM system. Officer alts can be identified by either their Silver Axe rank, or a chat handle common to all their characters in brackets next to their character name.
Joining Kiss My Axe is easy! All we ask is that you read the Guild Rules and complete the application accessible via the link at the bottom of the rules page. Once we have received and approved your application, an officer will be in touch.


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I generally am not an envious creature since despite outward appearances, most people often have more complex and hidden weighty baggage than even I am able to stuff into my tiny overhead bin. Anyway my life has been reasonably charmed with good calories, chances, and a Teflon-tempered family willing to still walk me even when I gurgle, grouse and grumble. So it's sensible to just stick with my own known quantity of crazy and slog through a routine trying not to inadvertently break other people's stuff or publicly scratch too vigorously, except when buying lottery tickets.
I will admit though I do gaze upon the neighbor's ol' yellow dog and at times admire his simple, unpretentious and seemingly perfect existence. Even with all of the positive support surrounding me I still have to constantly consider consequences and what people may think if I make odd choices or do unusual things. That's not the case for that geezer-mutt next door since he doesn't care about shallow hidden whispers from others on the color of his coat, his mental acumen, health, and of course the enduring ripeness of his scent.
It would be great to just dash out to the border of the front yard, mindful of the underground shock-wire of course, and gleefully start yelling at door to door salespeople and politicians who dare approach? Who wouldn't love the freedom when they get the urge to purge while on a walk, to just just stop, drop, and wrangle a rope or two to green up a neighbor's lawn and lubricate their mower's wheels. Life would be a lot easier if I could chew on furniture to brush my teeth, did not have to wash or even wear clothes, and got to lap up my coffee right from the floor rather than messing with putting it in a mug first.
Since I reckon I could get through puberty by the age of 2 and on to senior discounts by 3rd grade, even with the whole 7 to 1 aging thing, clearly a dog's life is looking pretty attractive to me right now. Despite that few dogs work for the government, some do have a bad reputation for harassing postal workers, which I find unbelievable since I'm sure they ALL must be in the same union. Given the similarity of great lifetime benefits, low and slow work expectations moving papers from street to stoop, and walking around unshaven and hairy - how else could you explain it?


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WASHINGTON (AP) -- Federal Reserve policymakers are divided over when to end extraordinary measures intended to encourage more borrowing and spending to help stimulate the U.S. economy.
Minutes of the Fed's March 19-20 meeting show a few members want end "relatively soon" a program that is spending $85 billion a month to purchases bonds, saying the costs likely outweigh the benefits. A few others saw the risks as increasing quickly and said the purchases would likely need to be reduced "before long."
Many members said an improved job market could lead them to slow purchases within a few months. A few said economic conditions would likely justify continuing the program until late this year.
The minutes were released earlier than planned after the Fed inadvertently sent them prematurely to congressional staffers and lobbyists.
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Thursday, September 17, 2009
Oh for Keat's sake. Seriously.
8 comments:
- some guy on the street said...
Not just gooey, but *flat*; it's like they tried to make pancakes, but left out the eggs AND the baking powder! The delivery just sounds dead, it has no conviction --- and I thought trailers were supposed to distill the most thrilling clips from a film! What's up with that!?
- September 17, 2009 at 5:34 PM
- Meredith said...
Yeah, "flat" is the other word I was looking for. The dialogue is very script-y and blah.
- September 17, 2009 at 8:54 PM
- Meredith said...
Actually, now that I've read the (mostly positive) reviews, I would like to see it!
- September 19, 2009 at 9:56 PM
- some guy on the street said...
There's a cliche Alexander Pope quote that goes here.
Do let us know how it goes?
- September 21, 2009 at 8:51 AM
Mereditha! Ecquando sententiam tuam de hac pelicula nobis tandem ostendes? Iamne eam spectasti? Equidem hodie vesperi sic feci. Sat placebat. Est, opinor, pelicula perpulchra. Quidnam autem censes tu?
Spero te optime habere atque oppido tibi placere versari Lexintoniae atque apud Instituto. Oro salutes Terentium Milenamque, necnon Luciannam, meis verbis, et cura uti in Christo magnopere valeas. M
- October 10, 2009 at 9:29 PM
Oops, that's what I get for changing a construction at the last second: it should read apud InstitutUM, not -o. Pax et bonum!
- October 11, 2009 at 7:59 AM
- Meredith said...
Salvus sis, Marcelle - I'm so sorry I haven't gotten back to you yet! First I was sick, and then I was grading midterms etc.... I'm going to see the movie this weekend, and I'll write to you then!
- October 21, 2009 at 8:27 AM
Thank you so much for the review. Eat your heart out, Roger Ebert! (I mean that!) See my crazy Latin comments up at that entry for more of my response.
I hear you on the grading: I have a whole crop of midterms to grade for my Gk Civ. class by tomorrow! But it really is wonderful to teach: it's something I've very much missed these last few years after Kentucky.
BTW, while I'm writing this, do you have any plans for coming to the conventiculum this year? I am trying to spread the word as best I can around here.
Well, off to read Herodotus. Ciao for now. M
- October 26, 2009 at 12:44 PM


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If you a are toy enthusiast who happens to visit the Philippines soon, then going to San Juan City, Metro Manila should be on your itinerary.
At Greenhills Shopping Center you can find lots of bargain items from electronics, mobile phones, computers, dining, entertainment-and anything you can think of might be there too. Well saving the best for last, this shopping mall is a treat for toy hunters because there's a number of toy store chains inside the shopping center which are located at the V-Mall (Viramall) and the Shoppesville Plus.


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Team: Juventus
Home or Away: Home
Years Active: 1984-1987
As Worn By: Michel Platini, Aldo Serena, Antonio Cabrini, Michael Laudrop, Zbigniew Boniek, Marco Tardelli, Paulo Rossi & Liam Brady
In Italy there's a certain style and history to the vertical black stripes used by the big European powerhouses of Inter, AC Milan and Juventus.
English influence in the early years of Italian football is widely evident, perhaps most notably with the cross of St George on the club crest of AC Milan and the use of the English 'Milan' rather than Milano.
But elsewhere in North Italy the giants of Turin also bear evidence of English influence. When you think of Juventus you instantly think of the famous black and white stripes of their shirts, but the original colours of the club were in fact pink and black.
So where did the black and white stripes come from? Well, fed up with how the pink shirts would quickly fade after a couple of washes, Juventus asked one of their members, Englishman John Savage, if he had any contacts in England who could supply new shirts in a colour that would better withstand the elements. John had a friend who lived in Nottingham who duly shipped out black and white striped shirts to Turin as he was a Notts County supporter!
A good thing too – it's hard to imagine those magnificent players from the mid-eighties holding aloft all those trophies wearing pink!


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Dr Oz: What's Your Ayurvedic Body Type?
Using an ancient technique known as Ayurvedic medicine, Dr Oz wanted to help his viewers "tap into their inner calm" and better understand their stress. Ayurveda, translated as "the science of life," is from India and aims to prevent and treat disease by balancing your mind, body, and spirit using the five elements of nature: earth, water, fire, air, and space.


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So how troubled was the Compaq/Ammirati relationship? Bad enough that Compaq CEO Eckhard Pfeiffer & directors spent time in board meetings bemoaning Ammirati's work. Pfeiffer was primed to move when Digital shop DDB Needham pitched and won the account. Pfeiffer & DDB now must work to change the image of Compaq from the world's No. 1 PC maker to the world's No. 2 overall computer maker. Pfeiffer restaged Compaq once -- in '91, when he became CEO, Pfeiffer fired O&M and turned Compaq into a maker of low-cost, low-margin PCs. He was decisive then on the agency front: Two minutes into Ammirati's pitch, Pfeiffer & Chairman Ben Rosen halted the meeting and called in their lieutenants. Ammirati won Compaq by presenting a strategy that happened to be wholly in sync with Compaq's "skunkworks" development of a cheap PC -- just as DDB this year presented a strategy and campaign dead-on with where Pfeiffer wants to take Compaq. One footnote: Compaq's regional direct biz could stay at Ammirati Puris Lintas despite DDB/Omnicom desires to take it. Compaq seems happy with that APL work, and direct always has operated independent of Compaq's global advertising. For now at least, APL keeps the biz.
Bozell to Jeep: Go to Hell
Jeep and agency Bozell donated a "Welcome to Hell, Mich." sign to the tiny Upper Peninsula burg, the star of a Jeep Grand Cherokee wintery spot. The commercial used a computer-generated Hell, Mich., sign, but the not-so-hot town now has an official sign -- right outside the Devil's Den liquor store.
A bumpy ad that didn't fly
Panasonic PC Co. and Renegade Marketing Group, pushing Toughbook PCs in the new "Take it" print campaign, figured United, American and Delta inflight mags were the ideal place to run an ad paying tribute to the deaths-by-air-turbulence of lesser notebooks. The airlines refused, apparently seeing little humor in an ad with the headline, "The airline gave my business the chair." Says Renegade prez Drew Neisser: "Just because Panasonic Toughbooks take it doesn't mean the airlines will." Bet Drew gets bumped next time he flies.
Winkler flies . . . copycat Cole
Winkler was on board at Reno Air before Winkler was on board at Reno Air. The deal: The SF agency just won the airline account, but boss Agnieszka Winkler has been a Reno Air board member since 1994. . . . Ziff-Davis is opening a sales office in Detroit to go after car ads. . . . The first parody of new Levi's ads is out. "Kenneth wore them, too," says an outdoor pitch with red type, a white background -- and a Kenneth Cole logo. The ad was created in-house. . . . Peter Sealey had an easy job in the mid-'60s as asst. brand manager on Crisco: He could reach 80% of women ages 18 to 49 with three 60-sec. spots on daytime soaps. What would it take now? The marketing consultant and ex-Coke exec, speaking at the ANA's Biz-to-Biz Mktg. Comm. Conf. in Fla. last week, figures he'd have to run 97 prime-time :30s to get that reach. Not that anyone bakes or uses Crisco anymore.
Compiled by Bradley Johnson with news from Alice Z. Cuneo, Jean Halliday and Anthony Vagnoni.
Got an Adage? Tell Brad by phone, (213) 651-3710, ext. 111; fax, (213) 655-8157; or e-mail, [email protected]