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Melissa L.
1-2 lbs Sirloin (trimmed and cut into big chunks)
1 onion
1 bell pepper
2 – 3 cans stewed tomatoes (We like a lot of tomatoes)
Flour for dredging
1. Dredge the sirloin chunks in flour and fry just until lightly browned. (Does not need to be cooked through). Put Sirloin in crock pot.
2. Dice onion and bell pepper then place in crock pot over and around sirloin.
3. Pour stewed tomatoes over sirloin, onions, and bell pepper.
4. Cook on low for 8 hours.
5. Serve with mashed potatoes (my family uses the sauce like gravy…we LOVE tomatoes!)
12 hours ago


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Jan 22
First Dnd session
A Draco-Aboleth, Drow, Grey elf, and Human dungeon delv a kobol ruin to retrieve Skrons (the humans) ancient sword. It brings the party together! M flirts and embarrassed Skron. Seth spends four weeks on a model of his litch that defies the laws of awesome.
Second Dnd session
Mom has disapeared! Skron is considering suicide, (no longer in the campaign though M is keeping closeish with him). At his house a mysterious stranger named Justin appears asking about Mom. Luke through completely accidental means somehow ended up with his wallet that reveals his name to only be Justin on his drivers licence and strange writings that none can understand! (Atlantian High Speach!) Eventually after much searching Mom was discovered going nuts at his comic shop punching a stand up master chief and stealing about all the Love Hina he could carry. Mom is found with a book made of the prime pages of Love Hina that strangely follow the pattern M..O..M…M..O….M … ect. After takeing him to the hospital Justin seeps to be stalking mom and threw daring and stealth Skron (he showed up to talk to mom) manages to sneak him out using his new found powers as a Sin Eater!

subset: commoncrawl


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Ana Ivanovic Peep Toe Pumps
Ana Ivanovic's strapless dress and black patent leather peep-toes were a classic pairing.
Ana Ivanovic Strapless Dress
Ana Ivanovic shimmered in a strapless silver and black brocade dress at the pre-Wimbledon party.
Browse: Ana Ivanovic | Peep Toe Pumps | Strapless Dress
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Sarah Castille
(Ruin & Revenge #2)
Published by: St. Martin's Paperbacks
Publication date: June 27th 2017
Genres: Adult, Romance, Suspense
Luca is the second book in a full-length, standalone series by New York Times bestselling author, Sarah Castille, set in Las Vegas and featuring deliciously sexy mafia bosses and the women who can't help but love them.
Luca Rizzoli was nearly destroyed by a brutal betrayal that cost him his family. Now a ruthless crime boss in Las Vegas, he lets nothing touch his frozen heart…until a smoldering encounter with a beautiful stranger ignites his passion. One night isn't enough for a man who takes what he wants—and Luca will do whatever he can to possess his mysterious temptress…
Police detective Gabrielle Fawkes lives for revenge. She lost everything at the hands of an unforgiving ruler of the Vegas underworld. Now she wants to see him six feet under. But when a near-fatal attack leads her into Luca's arms, what was meant to be one night of unbridled passion becomes something forbiddingly more. Luca has his own agenda, but when strong, determined, kick-ass detective Gaby sets her sights on her target, Luca feels compelled to stand by her side and protect her at all costs. However, pursuing danger comes at a high price—and both Gaby and Luca must work together in order to eliminate the dark enterprise that threatens them.
Goodreads / Amazon / Barnes & Noble / Kobo / iBooks / Google Play / IndieBound
"An engrossing erotic crime drama that will leave readers wanting more." – Library Journal
"With sizzling love scenes, taut plotting, and a hair-raising finish, Castille's romantic thriller will appeal to her existing fans and win her new ones." – Publishers Weekly Starred Review
"Luca is a fast-paced, action-packed tale balanced by humor, heart and family." – RT Book Reviews 4.5 stars, Top Pick
"Buonasera, Gabrielle."
Gabrielle's heart skipped an excited beat at the deep baritone of Luca's voice. She looked over her shoulder, her smile fading when she saw him glowering behind her. This wasn't Luca as she'd seen him in the restaurant. His eyes were cold, dark, and focused not on her, but on the man beside her.
"Is there a problem here?" Luca asked.
"Nothing I can't handle." She smiled at Ron. "This is the friend I thought I saw."
Ron's gaze flicked over Luca and he backed away, clearly not willing to challenge a man who looked like he was just waiting for an excuse to wrap his hands around Ron's throat.
Luca chuckled softly watching him go. "Yes, I remember. You told me in the hospital you can look after yourself, and yet somehow you got shot."
"I'm pretty sure Ron didn't have a gun."
Luca slid his hand around her waist and pulled her into his body, an overtly possessive move that sent a delicious shiver down her spine. "And if he did?"
Pumped with adrenaline that he had come to find her, she boldly leaned up and whispered in his ear. "I have one, too."
Far from being surprised, he gave an approving rumble. "Girls with guns are high on my fantasy list."
"I'm a woman, not a girl."
His gaze dropped to her breasts and she felt her nipples harden. "Yes, you are a woman. Sei tuna donna motto bella."
"I don't know what that means, but it sounds sexy when you say it."
"You think I'm sexy." It was a statement, not a question and she laughed when a slow, satisfied smile spread across his lips.
"I suspect you already knew that. You could seduce a woman without even opening your mouth."
His hand dropped lower, curving over her ass. "Am I seducing you?"
"I want to fuck you," he said bluntly.
Caught off guard by his bold statement, she didn't respond right away. If he'd been any other man telling her he wanted to fuck her after meeting her only twice, she would have laughed him off. But she'd learned to trust her instincts on the job and her instincts told her Luca wouldn't hurt her. For some inexplicable reason, she was deeply attracted to him. And after two years of feeling numb, the emotions and sensations coursing through her body were an incredible rush. Why not have one night with him? One night where she could let go of the sorrow of the past and the stress of the present. One night where she could do something she'd never had the courage to do before. One night where she could live, feel, breathe again. One night of passion.
"What about the woman I saw kissing you outside?"
He lifted a dismissive hand in the air. "It was a friendly kiss. We're not together anymore."
"Then maybe your wish will come true."
Author Bio:Sarah Castille is the New York Times and USA Today bestselling author of the Redemption Series, Ruin & Revenge Series, Sinner's Tribe Motorcycle Club series, Legal Heat series and the Club Excelsior series. A recovering lawyer with a fondness for dirty-talking alpha males, she now is a full-time writer, who lives on Vancouver Island. Sarah's books have been listed as Publisher's Weekly's Top Ten Picks and Best Summer Reads, and Amazon's Best Romance Books of the Year, and have won numerous reader's choice awards including the Holt Medallion.


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Sri Lanka recorded its first 3-0 "whitewash" of Australia. They had already inflicted this on West Indies and Zimbabwe in 2001-02 and Bangladesh in 2007. Sri Lanka has never played a series of 4 or more Tests.
It was also pointed out that Australia were "whitewashed" in their previous tours in Asia since early 2013: 4-0 by India, 2-0 by Pakistan in UAE and now 3-0 by Sri Lanka.
For the 29 Tests between these countries, Australia lead Sri Lanka 17-4 with 8 draws. In Australia it is 11-0 with 2 draws. In Sri Lanka, Australia still lead 6-4 with 6 draws. Until this series Sri Lanka had only won one Test against Australia, which was in 1999-2000.
Sri Lanka has won Tests in all countries except Australia and India.
Coming to the specifics of SL-Aus Tests:Batting
Most runs (500 and more):
Mathews is the only current player here.
Highest innings (135 and more):
Kusal Mendis is the only current player here. He recorded the highest score for SL v Aus in SL, surpassing Gurusinha's 137 in 1992. However the overall SL v Aus record is 192 by Sangakkara in 2007-08.
M Hussey is the only one with 5 centuries. No one else scored more than 3.
The most 50-plus scores are 8 by Clarke, Ponting and Sangakkara.
Now for batting averages (minimum 20 innings, all instances):
Strike rates are also available for all of these cases. Jayasuriya has the highest with 65.70, far ahead of others who are in the low 50s.
Now for bowling:
Most wickets (12 and above):
Herath with his 26-wicket haul in this series crossed Warne and Muralitharan to top this list. Starc, Lyon and Dilruwan Perera are also here.
Best innings bowling (6wi and above):
Herath (3 times), Starc and Dilruwan Perera make this list. Herath's 7-64 is the best for SL v Aus, surpassing his earlier record of 7-157 in 2011. Starc's 6-50 is the best for Aus v SL in SL.
Best match bowling (8wm and above):
Herath (13-145) and Starc (11-94) recorded the best for their teams. Again the records of Muralitharan and Warne have been toppled. Herath (again) and Dilruwan Perera appear lower down.
Bowling averages (minimum 2000 balls bowled, all instances):
Herath has the best average.
Vaas has the best economy rate, just ahead of Herath and Warne.
Herath has the best strike rate.
Now for fielding:
Most dismissals (10 and more):
The first few names are not surprising. The most stumpings are 6 by Kaluwitharana, most catches by keepers are 32 by Gilchrist and Healy, and the most by non-keepers is 20 by M Jayawardene followed by 16 by Ponting.
Nevill and Smith are the only current players here.
The best fielding in an innings is 5 by Gilchrist and Healy.
The best match fielding is 8 by Gilchrist and Healy (who else?) followed by non-keeper Hayden with 7. That was a share in the world Test record for some years until Rahane surpassed it with 8 last year.
Best dismissal rate (minimum 20 innings fielded, all instances):
Sangakkara heads this list, while Gilchrist and Healy did not play enough in these Tests to be counted. M Jayawardene has the best rate for non-keepers, followed by Warne.
All-round performance (overall):
Vaas is the only one to have pretensions of being an all-rounder. See the modest criteria to be met here.
All-round performances (match): Fifty-plus innings and 5wi in the match:
Only two instances here, including Dilruwan Perera whose contribution is more than that of Reiffel.


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After poking around the concepts of raster and vector images, I really wanted to dive a bit deeper into the most common form of vector image you will find today: fonts. Most of the fonts you run into today on a Windows system will be either True Type or Open type fonts, which are vector (outline) fonts. And, just like vector images you draw yourself (or metafiles that contain instructions to draw vector images), fonts have to be rasterized before you can display them on a screen. (Unless, of course, you procured your monitor from an old Asteroids video game machine, in which case it can render true vectors.) Rasterizing fonts has the same considerations as rasterizing any other vector images - when you map an infinitely precise mathematical line segment against a discrete pixel, you need software to determine what each pixel should display. With most vector images, it uses a generic algorithm. The results you obtain using this same generic algorithm against fonts can be disappointing, to say the least.
When you render text using Windows forms, you can specify the Text Rendering Hint on the Graphics object. I created a short program to iterate through the various options. This is the code that I used:
protected override void OnPaint(PaintEventArgs e) { Graphics graphics = e.Graphics; string text = "the quick brown fox jumped over the lazy dog"; SizeF size = graphics.MeasureString(text, Font); using (SolidBrush brush = new SolidBrush(ForeColor)) { for (int i = 0; i < 6; i++) { graphics.TextRenderingHint = TextRenderingHint.SystemDefault; graphics.DrawString(((TextRenderingHint)i).ToString(), Font, brush, new PointF(0, size.Height * i)); graphics.TextRenderingHint = (TextRenderingHint)i; graphics.DrawString(text, Font, brush, new PointF(125, size.Height * i)); } } }
Let's take a look at what we come up with. For this discussion, I am not interested in the differences between various anti-aliasing options, such as clear type. Personally, I'm fanatical about turning on ClearType everwhere that I can, but that is beside the point. The differences I am interested in looking at are between the GridFit enumeration values and the rest. (You can think of the GridFit suffix as basically means to use font hinting. However, this isn't entirely true. For grid fitting, the font glyph outlines are actually being moved around to best fit the bitmap grid On top of that, font hinting will be used to make additional suggestions to the rasterizer as to how the glyph should be rendered.)
8-Point Segoe UI with Various Text Rendering Hints
As an aside, I am a big fan of the Segoe UI font, which is the system font for Windows Vista and is also the font used by the 2007 Office System. Curiously, while a variant on this font is used for Windows Mobile 5.0 Smartphones, it is not used for Windows Mobile 5.0 Pocket PCs. And, unfortunately, the Palm Treo 700w I use is built on the Pocket PC version. I have absolutely no idea why I am stuck with Tahoma on my phone, which I find much less pleasurable to use. Bummer.
The differences are much more obvious on smaller fonts, which is why I selected an 8-point font. If you zero in on the SingleBitPerPixel rendering, you will notice that some of the characters aren't even complete! This is where font hinting helps out. It is a way that the developer of the font can make explicit suggestions to improve rendering.
Why might you care about this? Well, I found a few useful nuggets out of this little exploration.
First of all, if you are concerned about performance, it's good to know what your costs and trade-offs are. Rendering fonts includes rasterization if you are using an outline font. If you turn on hinting, then you have to actually run code (and yes, hinting code can contain loops) above and beyond rasterization code. But, from a trade-off perspective, it's very clear to me that these are CPU cycles that are very worthwhile! If you use bitmapped fonts (and there still are some in a standard installation of Windows) then you do not have to pay either cost. However, you also can't take advantage of anti-aliasing - either standard or clear type. (Personally, I can't stand to use software that uses bitmapped fonts any more. If it doesn't support clear type, and I am not compelled to use it for some reason, I'll remove the program.)
Notice that there is an option for ClearType. Normally, you may think of ClearType as a system-wide setting, but its presence here should suggest that you can render fonts using Clear Type even if this smoothing technique has not been enabled system-wide! While normally you would generally prefer to honor the user's system settings, with a reading technology as powerful as Clear Type that wasn't enabled by default when Windows XP was released (and where the setting is potentially non-obvious to somebody who isn't a power user) it is nice to know that you could provide this benefit to your user base without requiring them to discover this setting.
You probably noticed that the text we are outputting are not all exactly the same length. The GridFit fonts tend to be longer. This isn't entirely unexpected - if we are moving glyphs around to find the best fit for the bitmap grid we are rasterizing to, you probably expect that the movement will more often be to the right (on right to left text) so that you don't end up with overlap and crowding with the previous glyph. However, if you inject some code to use the Graphics.MeasureString API, you will discover that the length of the string is reported as always being the same, even though your eyes tell you differently! This is actually a more complex operation than it seems. To measure the size of a string, are doing a translation from a vector image to a raster image. This translation also includes grid fitting and hinting. Apparently, the MeasureString API is not running all of this code before returning a response, and the most obvious reason why is that it does this in the interest of performance. Considering trade-offs, the question then becomes this - how important is it to be to-the-pixel accurate, compared to the value of the CPU cycles that could otherwise be doing something the user could actually see. For example, I am using the MeasureString API to find an approximation of the string's height in order to space out my output. If the result is 1 pixel greater than it would otherwise need to be, do I really care? In this example, I do not. However, it's good to keep this in mind when you use this API.
You will also notice that I used the Graphics.DrawString API rather than the TextRender.MeasureText API. TextRenderer internally uses some font caching, as well as calling into the GDI function DrawTextEx. The result is that everything I render is rendered using hinted fonts, which made it a poor choice for the purpose of this demo. Wait ... it's using GDI instead of GDI+? I have heard (but I have not personally verified) that GDI font rendering is approximately 10x faster than GDI+ font rendering (1M glyphs / second vs. 100K glyphs / second). Of course, there is a reason why GDI+ takes more work - text is truly device independent using GDI+. Yet another tradeoff. If you are interested in the details, check out GDI+ Text, Resolution Independence, and Rendering Methods. Or - Why does my text look different in GDI+ and in GDI?.
Knowing about font hinting is also important if you are using text with GraphicsPath objects. The GraphicsPath object exposes AddString methods, and you can use this to include text in your path. However, internally, a GraphicsPath object contains nothing but a collection of points. There are no exceptions made to store text. That means that the text is stored as the points required to construct this image. Once the text is converted to points, there is no way to differentiate these points from any other points in the path. And this, of course, means that when you rasterize this path, you will be rasterizing the points comprising the text, leveraging none of the grid fitting and hinting provided by fonts. If your fonts are smaller, the outcome could likely be as unattractive and unreadable as the SingleBitPerPixel font rendering.
The final thing I pondered was this: if the technique of hinting so visibly helpful in rendering font vectors, wouldn't it be just as helpful in rendering arbitrary vectors? I certainly think so. Obviously, the completeness of a font has a much higher impact than the completeness of an arbitrary picture - you want to be able to process a large number of glyphs as efficiently as possible. However, as we slowly (glacially) make our way towards true device independence and vector images, I can foresee a need to support vector hinting on arbitrary vector images, and not fonts alone. I have no idea if or when this is coming...
Note that I am not an expert in the inner workings of fonts, and that I have discovered many of these things during the course of my exploration. I just need to use them. If you have something to add or correct, please feel free to comment, trackback, or email!


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Pet Food
Pet foods and their ingredients by their very nature are perishable and prone to oxidation. Storing them on the shelf for an extended period of time, has negative effects on their flavour, aroma, texture and nutrients. All food is a sum of its parts and topically added fats contribute significantly to the nourishing capability of modern pet foods.
During the course of oxidation, fat is relatively stable for a while. Then as antioxidants are depleted, the free-radical production overwhelms the intrinsic antioxidant capacity of the product and the pet food flavour as well as its aroma are negatively impacted.
CFS offers you a complete line of traditional and natural shelf life solutions to meet your application needs and to help you protect your finished products from oxidation.
We deliver high-quality innovative antioxidants with tailor-made solutions that enable you to retain control over your shelf life extension requirements.
Either separately or in combination, BHA, BHT and propyl gallate are effective in low concentrations to stabilize fats, protein meals and finished products that are highly susceptible to oxidation.
Xtendra traditional shelf life solutions utilize ingredients that have been long proven to protect the oxidative stability of your pet food product from the raw material stage right until the finished product.
Surveys indicate an overwhelming preference for natural ingredients.
The newer challenge to stabilizing fats and oils and final pet food products is the request for natural preservatives.
Animal and fish based fats and oils can be effectively stabilized with natural antioxidant systems; however, it is much more costly and requires more attention to the details.
Most natural antioxidant systems are built on a backbone of mixed tocopherols carried in a vegetable oil with added chelators and emulsifiers. Proper dilution, effective carriers and uniform dispersion are vital to successful use of these compounds.
NaSure plant based shelf life solutions are the natural option when an extended shelf life is needed. Rosemary extract and mixed tocopherols are just some of the natural ingredients used in our formulas that are high in antioxidant activity and very effective.
To know more about our products, please click here to fill the form or you could contact one of our offices directly.


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Who Is On My Wifi is as the name suggests, a tool for the detection of all computers connected to a local WiFi network. The program automatically informs us of connecting to an unknown computer networks. This application allows you to protect our network
Find unknown computers on your internal network and block them.
If you are starting the development of some software that must manage WiFi connections and settings in Windows, you will be faced with the following problem. There are two versions of Windows that have API for WiFi networks management: Windows XP Service
CommView for WiFi is a program for analyzing network packets on wireless networks for 802.11 a / b / g. The program displays a list of available connections, IP statistics and examine individual packets. Packages can be deciphered by the users WEP key or


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Rock shows and other long weekend antics
Happy September, everyone!
Post-Labour Day, there always seems to be something qualitatively different in the air. Paired with the first leaves tumbling to the ground, I am afraid that autumn may indeed be creeping up on us.
But I digress... because I'm sure you are all biting your nails with anticipation of my long weekend antics!
(humour me, okay?)
My weekend kicked off with a proverbial bang, for certain...
A friend from a previous city of residence recently moved my way. On Friday, he invited me to meet him at an infamous clothing optional beach. I highlight the optional, as while I don't have a problem with nudity, I'm also a little hesitant to disrobe in front of just anyone, especially in the days of cell phone cameras and voyeuristic websites. While negotiating the plans, he asserted that he, too, would remain clothed. However, on the actual day of, as I was on my way to meet him, we exchanged a series of text messages, starting with him saying "I have to warn you, there are naked people here", to "Actually, I decided to go naked, as it felt too awkward to be clothed", to "Do you mind if I am naked when we meet?"
I told him that, if he was comfortable with it, I could handle that.
All the same, it is definitely one of the odder experiences in life to witness a completely platonic friend of several years (who, I may add, I have never been attracted to-- and is also married and a completely unskeezy guy) striding towards you, completely nude. Especially one who always fell more into the bounds of conventionality than myself. And although the awkwardness dissipated rather quickly (the fact that he was so nonchalant helped), I still kept on having "Oh my God, I've seen S's penis!" run through my mind for the rest of the day.
After dinner with my now non-nude friend, I met up with some girl friends, who escorted me to a friend's house for some drinks before we made our way out. Which was all fine and dandy... except for the fact that it was the DIRTIEST. HOUSE. EVER.
Our city is unfortunately on Day 47 of a garbage worker strike, which means that, along with being randomly blasted with rank odors as you are walking down the street, most houses are experiencing greater than normal fruit fly populations. I have about five buzzing around my kitchen that seemingly don't seem to care whether my dishes are clean or not, as do most people I know who live in this city. However, that is no excuse for over 50 fruit flies in the bathroom alone!
I seriously cannot imagine why people can not only live in such squalor, but not even be embarassed of it! Laundry all over the living room, hundreds of wine bottles in the kitchen, odd wet looking stains on the rug, mold in the bathtub... and you invite people over? I was creeped out by the fact that I hadn't worn socks and had to place my bare feet on their possibly contaminated floor that had never seen the gentle touch of a mop.
However, lest you get the impression that my long weekend was all about a general sense of discomfort...
Whilst flipping through the channels on Sunday afternoon, I came across not just one, but TWO Freddie Prinze Jr. movies on at the very same time! Ah, Freddie, your puppy dog eyes and ability to play a teenager despite being around thirty years old make me yearn for the days of yore. Your films also make me wonder why my prom didn't have spontaneous choreographed dance routines. Or even an epic battle for prom queen, and, of course, your heart.
The main theme of the weekend, however, was not heartthrobs, but rather rock concerts!
Saturday night, the Duke, his roomie and I went to see Queens of the Stone Age. We were a little apprehensive-- not at QOTSA's ability to rock, but rather about the venue, which at the last minute had been relegated to a suburban arena typically used for Triple A hockey due to the very same strike that has also resulted in garbage pile-ups also resulting in the closing of the concert venue. However, the show did not disappoint-- the band rocked out for a solid two hours, and I danced my ass off.
One of the most entrancing things ever must be watching a mosh pit in flickering lights-- it looks as though it is entirely its own entity.
A non-highlight? Drunks teenagers trying to mosh while in hockey arena stands-- in between doing the spin your partner, do-si-do square dance move.
We also went to see Tokyo Police Club on Sunday night. Fitting with one of the weekend's subthemes-- that being lack of cleanliness- -the floor was so sticky it pulled my slip-on shoes off. Although they probably suffered in contrast to the night previous' performance, the band still put on a solid show, if a little short.
I'm actually in the midst of a rather lovely concert bonanza, with another four shows this month alone.
But now, alas, with the return of fall comes the return to school. My eighth year, to be exact, which is a little intimidating to realize. Kicking off with a 6:30 rise tomorrow and a return home some 13 or so hours later.
Freddie.... come rescue me!


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Dear travelers and dreamers,
Our adventure continues with memories from our road trip's last stop in Munich. After several days in Berlin, Prague and Vienna, (links: Berlin post, Prague post and Vienna post) on 11 July 2014 we arrived in the capital of the German land Bavaria. We were very happy because we planned to see Diana, a friend living in Munich for some years.
We met Diana in the city center in front of the splendid new Rathaus. We were so hungry and thirsty and after a bit of walking around we arrived at the Hofbrauhaus. We had a wonderful experience there and it's the place to get a taste of Bavaria. After more walking and drinks we called it a night and went to the hotel.
The next day, as Diana suggested, we visited BMW Welt and the Olympia Park. BMW Welt was great, wonderful presentation and architecture, all the nice cars and the new technologies. You can find the newest BMWs, Minis and Rolls Royces. The entry is free at BMW Welt and for the BMW Museum it is 10 euros (for more information check here – BMW Welt).
A visit to the Olympia Park has a lot to offer, you can climb the Olympiaturm and get a nice panoramic view of the city and a Rock Museum, you can check the Sea Life and many other things (more info here – Olympia Park). We ate there too, at the restaurant Olympiasee, it was a great place for a quick and budget friendly bite.
After one park, we went to another park – the English Garden. What to do in this big park? Uhm…walk a lot, drink a beer, repeat until you get back in the city center. 🙂 That's what we did.
Munich is the city I first tried sushi. I am very adventurous when it comes to food and I was very curious about sushi. I really liked it and I will eat more of it in the future.
Munich was so much fun, we walked a lot, smiled constantly, drank and ate loads. The weather was great and the city has a nice energy and cool vibe. I think that every summer day feels like Oktoberfest here.
Have you been or plan to go to Munich? What are your thoughts about it?


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The Public Procurement Service (PPS) is one of Korea's central administrative bodies that provides public institutions with materials, facilities and services from supplying companies that they need. With the rapid spread of the Internet and Korea's advanced level of Information Technology, the nation's procurement system, also, is going online. Furthermore, a growing number of developing countries where issues of budget waste, lack of transparency and corruption are considerable are trying to import! and benchmark Korea's online e-procurement system.
Procurement officials overseas visit Korea to learn
Korea International Cooperation Agency (KOICA) conducted a training program "Public Procurement System Establishment" for 18 participants from 8 countries including Uzbekistan, Egypt, Morocco, Ghana, Tunisia, Senegal, Cote d'Ivoire, and Uganda. From September 2 to 18, the participating officials took various courses on the strategy for establishing the e-Government and e-Procurement system.
Korea exports e-procurement system to Costa Rica
Costa Rica's e-procurement system which opened in July 2009 was constructed by Samsung SDS for USD 8.3 million. Recently, a total of 9 systems were launched including the electronic bidding, security/authentication, electronic contracts, electronic payments, electronic documents, document distribution and others. Samsung will support the operation until December and then transfer the controls over to ICE (Instituto Costarricense de Electricidad).
With the introduction of the system, the Costa Rican government will be able to operate efficiently through integration, standardization of procurements. Also, it is expected to contribute to the transparency of procurement and the efficiency of the bidding companies.
Laura Chinchilla, President of Costa Rica said, "I am very pleased because the e-procurement system improves the efficiency of public institutions and provides high-quality services of government agencies; it provides equal benefits to all the citizens." She also thanked South Korea's embassies and Samsung SDS for their efforts in making the successful launch.
Through the project to spread Korean online procurement system to foreign countries, Korea's software and IT consulting companies are accumulating their know-how on overseas projects and improving their international competitiveness. Also, efforts are being made to make the Korean e-procurement system a global standard.
Not so many people are aware Korea has an advanced procurement system like this. Promoting it to the world must surely be a way to raise Korea's brand value!


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Outraged by the actions of a small Kansas church group that staged protests at the funerals of U.S. troops killed in combat, Michigan lawmakers several years ago passed legislation making it illegal to "adversely affect" a funeral.
Outraged by the actions of a small Kansas church group that staged protests at the funerals of U.S. troops killed in combat, Michigan lawmakers several years ago passed legislation making it illegal to "adversely affect" a funeral.
But the statute's target was far too broad. It ensnared a middle-age couple in a lengthy legal battle after they chose to silently express their criticism of the Bush administration while taking part in a funeral procession for a family friend who was killed in Iraq.
Recently, a federal judge struck down a central provision of the state's law, saying it violated the First Amendment of the U.S. Constitution and was unconstitutionally vague.
We agree. Like most people, we abhor the conduct of the Kansas parishioners who show up at military funerals across the country to loudly protest that God is punishing the United States for tolerating homosexuality. But we cannot outlaw their actions without endangering the right of all Americans to voice their opinions.
Michigan's law illustrates the point. When Cpl. Todd Motley was killed in action in Iraq in 2007, Lewis and Jean Lowden were among the mourners at his funeral. The Lowdens had made homemade signs critical of former President George W. Bush and U.S. policy and placed them in the windows of their van. When they took part in the funeral procession, no one in Motley's family complained, yet the Lowdens were ordered by sheriff's deputies to pull out of the procession. They were arrested and their van was impounded. They were detained for about 24 hours, but criminal charges were eventually dropped.
Angered by what Lewis Lowden called the "shame and humiliation" he and his wife felt by being forced out of the procession, the couple filed suit challenging the law. The American Civil Liberties Union assisted in their case.
U.S. District Judge Thomas L. Ludington ruled that the Lowdens' rights to freedom of speech, due process and against unreasonable search and seizure were violated by their arrest, and recently he struck down the law as unconstitutional.
As vulgar and offensive as free speech sometimes can be, trying to limit it usually ends up infringing on the rights of innocent people.
Unfortunately, Jean Lowden died before the ruling was handed down, but she and her husband have helped to ensure that free speech will not be silenced in Michigan.


text: WASHINGTON -- Katie Couric plans to confirm this morning on "Today" that she is leaving the top-rated morning show after 15 years, and CBS will quickly announce, probably today, that she will take over the anchor chair once occupied by Walter Cronkite and Dan Rather. Couric, 49, decided Tuesday to use the occasion of her 15th anniversary, when the NBC program will be reflecting on her tenure, to look forward to the next chapter in her career, said sources at both networks and people familiar with her thinking. The sources, who first confirmed Couric's plans Monday, had expected the CBS negotiations to drag on a bit longer, but said now the network has wrapped up the negotiations and wants to go public as soon as Couric does. Bob Schieffer, the current CBS anchor, who had made clear that he did not want to keep the job indefinitely, said Tuesday: "I hope it is true. I've known Katie for many years. She's a first-rate reporter and a terrific interviewer. I love Katie and I think she'll love CBS News." The move by Couric, who will remain at "Today" until her NBC contract expires in May, will have repercussions throughout the broadcast schedule. NBC, which is determined to maintain its morning ratings lead, has offered her job to Meredith Vieira of ABC's "The View" and the syndicated "Who Wants to Be a Millionaire," who is still weighing the opportunity against family concerns. CBS is making a multi- million-dollar bet that Couric, who would be the first solo female anchor of a weekday network newscast, can boost the third-place "CBS Evening News." Couric, who attracted enormous publicity while considering her options, is said by those who know her to be brimming with ideas about how to adapt the evening newscast to her skills and personality. The "Today" retrospective at 7:30 a.m. today will feature video clips of Couric over the years, followed by her comments about her departure, and will have a less celebratory tone than otherwise would have been the case. Couric is close to NBC chief executive Jeff Zucker, her original producer on "Today," the sources said, and has been trying to manage her departure without hurting relationships with him and other longtime colleagues at NBC.


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Looking to de-clutter your desk? If you are like me, you have cables running all over the place and recharging your BlackBerry can often involve hunting down an outlet and your recharging cable. I have tried the BlackBerry multifunction desktop recharging platform that also had ports for earphones and found it very handy. The Seidio Desktop Recharging Cradle is a stylish, albeit simpler, desktop solution to desktop clutter and an easy-to-use accessory for both Pearl and Curve versions of the BlackBerry.
The Device
The Seidio Desktop Cradle was designed for the BlackBerry 8100 Pearl and will probably fit that well. However the design also allows for the Curve to sit well in the cradle. The cradle wouldn't hold the Curve if you tipped it over but is sits within the cradle for its intended purpose. This is a useful feature if you are making the change from one Berry to another.
You can also use the cradle with a rubberized skin or case still on, which is a huge advantage over similar cradles.
The unit comes with a USB to mini USB cable in order to charge your Berry through your computer. You can also synch your Berry through the same cable. My unit didn't come with a cable to an outlet, but there is a port on the rear to allow you to use the recharging cable that comes with your BlackBerry. You can purchase a separate cable and travel adapter if you wish.
The USB port is on the side of the unit not the bottom with is another good feature.
One thing to note is that the side switch needs to be in the charging position on order to have the Berry charge. There is an LED that does indicate charging to help avoid forgetting to flick on the switch.
My first reaction was to ask why there weren't internal points to slip your BlackBerry onto without having to use cables to recharge. But the lack of direct recharging points allows for the use of both Pearl and Curve, and the lack of a necessary outlet cable cuts down on clutter.
The cradle itself is sturdy and solid feeling and holds the BlackBerry well and is coated in a cool-looking matte, rubberized coating.
The Bottom Line
This is a pretty basic addition for the BlackBerry line of accessories. It is a pretty simple cradle that has two main features – it allows you to recharge without taking off your BlackBerry skin and is usable with both Pearls and Curves.
It helps declutter your life somewhat. I am always looking for my Berry on my messy desk and, if nothing else, this cradle gives you a place to put your Berry each day. The advantage of other rechargers that use charging points is you can lift them off the cradle without unplugging them if you get a call or message. With the Seidio cradle here having to unplug a cable is a bit of pain. But overall the pros definitely outweigh the cons.
|Buy Now:


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Spinners: Don't be silly! Spin is supposed to be fun! The room has loud music, funky lights and an energetic fun teacher. The only race that exists is the one within you. Everyone in the room started exactly where you started. Just have fun and don't worry we promise that the seat becomes more exciting after your first couple of visits!
Spinners: Many find their first spin class a little difficult. You have full control of the tension of the bike and in turn on how hard you go. If you need to take a break please do, just always remember to keep your legs moving to bring your heart rate down slowly. If you do need to leave the room for a few minutes, make sure to remove your shoes in the spin room (they turn into skates on the tiles!) and give your instructor a 'thumbs up' or 'thumbs down' so that they know that you are okay.
Spinners: All you need is water and spin shoes equipped with look keo cleats. Sorry! SPD compatible shoes or regular sneakers do not work for our bikes. Don't have them? No problem. We rent giro spin shoes for $2 and sell cold bottled water for $2. We provide complementary hand towels if you forget yours and rent large size towels for $2. If you bring your own water bottle, we have a bottle filling station that dispenses filtered water.
Spinners: Like yoga you should dress light. You are going to work hard and get sweaty. Many people find that shorts/tights and a light t-shirt/tank top are best. Whatever makes you feel the most comfortable. If you are renting shoes please remember to bring socks! Bring a change of clothes. Our studios have lots of space in the change rooms and showers for after your class.
Spinners: All of our spin classes are suitable for all levels. The instructor has no control over how hard you push. It is totally up to you how hard you want to push!
Yogis: Once you have checked in to class, head to the change room and get changed. After you get changed, you can go in to the studio and find a place for your mat. Many of our guests like to sit or lay down on their mat to get acclimatized to the room until class starts. When you are in the room, please do your best not to talk. We also ask that you leave your cell phone in the change room.
Spinners: Once you have checked into class, head to the change room and get changed. The tile turns into a skating rink with the spin shoes so for your safety, lets keep them off until you choose a bike! We ask that you please leave your cell phones in the change room. Once in the spin room, find a bike that you like, the instructor may ask that you choose the first two rows if it is a smaller class. For your first time PLEASE let your instructor help you to find the perfect bike set up! If you have trouble remembering this we have bike set up stickers for $2 to stick to your water bottle so you never forget! Out of respect for your fellow spinners we ask that we keep the chatter in the room to a minimum. Once you are all set up and feel good on the bike, clip in and enjoy the ride!
Most of all, spin and yoga are FUN! So enjoy the ride!


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Friday, 3 February 2012
Sister of the artist
Above is Fanny Mendelssohn (1805–47), sister of the composer Felix, as sketched by her husband Wilhelm Hensel and as pinned to his study wall and photographed on a sunny day by Dai Vaughan. Fanny, no less than her brother, had musical ability as both composer and performer. But she happened to be a woman. In 1820 her father wrote to her that while music was likely to beome Felix's profession, 'for you it can and must be only an ornament'. Her brother was supportive, but not to the point of encouraging her to publish under her own name: 'She is too much all that a woman ought to be for this.'
Dai Vaughan's Sister of the artist, set in the early 19th century, is a parallel fiction concerning a sister and brother, both talented artists. Interwoven with their story are fragments of other narratives – folk tales, let's call them – concerning siblings, language, creativity, the obstructions these come up against.
Dai Vaughan – born in 1933, author of fiction, poetry and books on documentary film, the field in which he has spent most of his working life – is not in the best of health; so I'm pleased and proud to say that this book has jumped the queue and is available from the CBe website NOW. (And if you press a certain button at the foot of the Books page, you can get both this and the Miha Mazzini novel for £13.50.)
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Sponsored post from Yvonne Estelle's
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Juliska's Country Estate collection will make any gathering look like a million bucks.
Head on over to Yvonne Estelle's to start shopping for your home.
Thursday, June 6, 2013
Yvonne Estelle's: Style for the home
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birthday, children, christian, church, comfort, faith, family, feelings, happy, joy, life, love, peace, prayer, relationships, thanks, travel, women
Hey shawty! (That's ME!) It's your birthday! (Still ME!)
Yes, it is my birthday and I am the big 3-8! Even though I do not feel 38, and very happy to report that I do not look 38. Although, I cannot tell you what 38 is actually supposed to look like, especially since no one seems to be looking their rightful age, nowadays. LOL! But, nonetheless, I thank the Lord that I still maintain great genetics and that I am still blessed to have a fun-loving, childlike spirit.
Today, before I even got out of bed, as I do everyday, I gave my thanks to the King, my Lord, Jesus Christ. Without Him, I literally would not be here. And regardless of the traumas I have endured in the past, I can't say that I would have it any other way. I know He is blessing me and just waiting to give me more, More, MORE!
Double RR was the first phone call of the day. October is going to be 6 months with him. (YAY!) This man loves me. I mean, he just loves me and adores me. I had to finally admit to him that it was feeling kind of weird with the way that he just showers me with all this love and attention. I am so not used to it. And it made me feel sad in a way because I was saying to myself, I was really messing around with some straight up JERKS in my past!!! It shouldn't feel weird that someone really loves you and cares for you and shows you, right? That should be a norm, but unfortunately, it is not always this way.
It made me realize that in all of my past relationships, I was the one always chasing the man (or rather, the boy) and showing all the love and affection and attention. Don't get me wrong, my exes weren't horrible, stoic people, but the love that they showed, it wasn't how I needed to be loved. And I took it because I didn't know any better. And I thought it was "love." It might of been love to them, but I always felt like it was lacking, but couldn't express my thoughts/feelings to them. And because we were so young, they wouldn't have been very receptive to receiving them either. Even with my ex-husband, as we got older, he wouldn't listen to how I felt about anything. I just had to get past and get over. My feelings were never taken into serious consideration.
But Double RR is making me see the difference and the light! He sent me a birthday present that is coming this week, he sent me a birthday shout out on FB that totally embarrassed me a loving way. I am super, uber shy and his proclamation of love just made me turtle up! LOL!!!! Never has a man professed his love for me like that, publicly. Even before the internet, none of my exes would do anything that would showcase how they felt about me outside of the relationship. So, this is new. And I guess if he's shouting it from the social media mountaintops, this is real for him too. LMBOOOOO!!!!
It just feels really nice to be in love and to be loved by someone who isn't afraid to show love. The ladybugs and I are going to NYC in Oct for a weekend visit. I miss Double RR and I miss my dad. So, we're gonna go and see them both! The ladybugs don't know that we are going yet, though. It's a surprise. Plus, when I do tell them in advance about a vacation, they bug the crap outta me, so they are on a need to know basis. And right now, they do not need to know! They really adore Double RR and they are missing grandpa like crazy. They are going to be so happy to see them both!
Life is good! Happy birthday to me! 🙂


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|Sighting Report
|Occurred : 8/5/2009 21:09 (Entered as : 08/05/2009 21:09)
Reported: 8/11/2009 9:22:25 AM 09:22
Posted: 8/27/2009
Location: Kenna, NM
Shape: Formation
Duration:5 minutes
|Lights flashing in sky.
Low flying string of large yellow lights in northwest sky above canyon, approx. 10-15 lights in sideways s formation. The lights then turned off one by one from right to left. The lights then appeared to the west in a u shape, like a smile, turning on one by one from right to left. The lights turned off again in same sequence. The lights were not spotted again.


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Anyone under the age of 13 and their families can join in to make art inspired by the fantastic shapes and brilliant designs of the works of art, to make their own RARRK-style collages and drawings. We will use art made from the everyday objects around us - just as the RARRK artists use bark, tree trunks, and natural pigments from their local environment - only we will be using egg boxes, newspaper, adverts, and packaging.
The workshop will be led by Ben Street, who has been an arts educator for the Museum of Modern Art and the Guggenheim Museum in New York. Ben is currently an educator for the National Gallery, the National Portrait Gallery, and the Hayward Gallery, as well as a teaches the history of art at the Westminster School in London.
This event is related to RARRK - LONDON
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Sutherland Lyall talks to Adam Caruso and project architect Stephanie Webs of Caruso St John about designing a new gallery with performing arts space for Nottingham.
For at least seven years building up to the development of this project there had been discussions about a new art centre in Nottingham, a city which has existing galleries and a very active art and design scene. Nottingham Council decided to build a group of exhibition galleries with a space specifically for performance art, that lineal descendant of the 1920s Dada performance events and happening 1960s spaces. Most companies involved in such work have no fixed home, so Nottingham will now provide a venue for them.
Caruso St John was awarded the contract following a one-and-a-half hour interview, and started on a tour of similar spaces in Europe. Adam Caruso says: 'We often returned to the work of Gordon Matta-Clark and the way he had a restaurant downstairs from his studio in SoHo, New York. Something we were very interested in was the coincidence that our site was on the edge of Nottingham's Lace Market, a place rather like SoHo.
'I think the Nottingham curators could see that we were interested in their programme for the site, not an empty aesthetic.
We aren't really into aesthetics; we are interested in form.'
Working for a client which is also the planning authority can have its moments. But Caruso is enthusiastic. 'Nottingham has been an incredible city council and client, ' he says. 'Senior officers are key members of the team and senior planners have been absolutely brilliant. The council is very pro-business and pro-development.'
The architect's appointment was a standard SSA99 with no revisions. Arup did all the engineering and the quantity surveyor was Leeds practice Jackson Coles. Acoustic consultant Tim Lewers was among a number of specialist consultants who had input.
Caruso says: 'We have had a long relationship with access consultant, David Bonnett. You need access statements and when we worked on the New Art Gallery in Walsall with him, we could work strategically. Since then, everything has become much more circumscribed. Britain is in the forefront and is very demanding.'
The main contract is the local authority version of JCT 98 with full measurements. Caruso says: 'This is the first time we have had a single-stage tender for everything. We went out with a full schedule and full drawings. Modern construction is difficult enough to do but this is a complicated job and we were fastidious and neurotic, producing nearly 200 drawings. It's slightly absurd because the contractor won't have opened every one of them and after the appointment we have to make sure that he does.'
CADCaruso St John used MicroStation PowerDraft for the drawings, while some feasibility studies were carried out on VectorWorks.
The practice started off with Macs and used MicroStation. Caruso says: 'Changing to AutoCAD would have been too traumatic. We use a lot of big models but we don't do presentation drawings. We start to use CAD quite early as a design tool. But we don't think it changes the form of our architecture. Our production drawings are much like what they were when we were hand-drawing.'
The practice has recently used an extranet on a project at King's Cross but here, Caruso says: 'Emails are a general problem because contractors tend to use them instead of communicating. The extranet is good because of its effect on the quantity of hard copy. At Nottingham I have a feeling that because it is a conventional contract it's not necessary.
The practice uses the electronic version of NBS. Caruso says: 'There is one part of the envelope specification where we worked with Schumann Smith - even here the notes are all NBS referenced.'
Nottingham wanted a project manager and Caruso St John was involved in the selection of Hornagold & Hills. How does it feel answering to the people you have helped appoint? Caruso says he is very happy with the situation.
He says: 'I used to be hugely sceptical of project management, largely because historically we had to do everything ourselves. Working with Hornagold & Hills has been very good.
They have huge experience with Lottery funding and a fantastic capacity to marshal together everything needed to confirm the commitment the Arts Council is making. In the end we led the design team meetings; they led the project team meetings.'
BUILDING The triangular site is on the edge of Nottingham's Lace Market area, bounded on its west and north-east sides by roads. The site dips from the north down to the south, where there is a low-level access route from the rest of the city. A set of grand open-air stairs along the curving east wall manages the pedestrian transition.
The building is complicated by teaching spaces and offices along the outer wall and a basement cafÚ, but it can be viewed as a big warehouse with top-lit galleries, one 10m high, at the upper level, with a big 8m-high space in the basement for performances. This is not black-box stuff. To start off with, everything is to be painted white or left as natural concrete.
Caruso speaks admiringly of the theatre consultant, Charcoalblue, which advised on such things as moving theatrical rigs around the big space. 'Working with them has involved us in a very sharp, open process of developing new ways in performance space. It has been a really productive collaboration, ' says Caruso.
Project architect Stephanie Webs says a lot of value engineering has already taken place although the contractor has only just been appointed and the subcontract packages are yet to be let.
The enabling works, which involved rerouting heating supply lines, have been completed and the basic structural strategy agreed: building everything below ground-floor level in concrete, with the ground floor and above made of structural steel, clad mainly with precast concrete. These panels are scalloped, dark green, throughcoloured concrete made by Decomo, a number of them cast against a giant lace pattern to be specially crocheted for the job.
Webs says: 'We wanted the panels to be rough, fairly tall and to have areas of very detailed ornament. There was the idea of using lace as a pattern. And then came the question of how to transfer a lace pattern to the concrete. We have found a person who will do a piece of lace by hand, using much thicker thread than the original. But we are still deciding. Will we use the giant lace itself as a mould? We could do a 3D scan and a digital mould.
Or we could cast against it and make a rubber mould.'
The vertical panels will sit on a black concrete plinth and some sections of the elevation will have vertical, gold-anodised mullions to enhance the three-dimensional quality of the ensemble.
ROBUST INTERIOR On the ground floor, internal walls are 12mm plasterboard on 18mm thick water and boil proof ply on metal framing fixed to the gallery walls. This elaborate arrangement allows the plasterboard to have screws and hanging fittings constantly attached and removed. The performance-space walls are concrete or blockwork with a few plaster-on-metal frame partitions. The walls in fair-faced concrete will be the result of heavy persuasion and high-quality formwork. Webs says dryly: 'We have asked for sample areas. In the lobby and the bar area exposed concrete is not painted and we have ply panels to the walls stained in dark greens and reds.' WC walls are similarly stained MDF rather than ply.
Lobby and reception floors are an oak Triboard floor.
Webs says, 'We have used Triboard before this on floors and it can be used for furniture. It is laid up of three layers of solid oak each orientated at 90 degrees to the adjacent layer. The [sandable] top and bottom layers are 5mm thick and the core is 16mm - all solid oak. It comes in big 1.25 x 2.4m sheets with tongue-and-groove edges. The surface has 80mm-wide strips simulating floorboards.'
The ceiling coffers in the galleries are lined with cut and neatly sanded ply. Rooflights, made by Glazing Vision, have white powder-coated aluminium frames with security diffusing glass.
Gaps between the edges of several coffers will hold lighting tracks and double up as the means of extracting air from the galleries.
Acoustic spray from Oscar Acoustics has been applied to ceilings in the performance space, mezzanine, meeting room, bar and cafÚ.
Carpet from the Scandinavian Collection has been laid in the offices, and Triboard in the education spaces and the basement.
The flat roof is waterproofed by a liquid tanking system and then treated to a sedum extensive green roof. It is bedded between the rooflights and on the big canopy at the front door.
Architect Caruso St John Architects: Adam Caruso, Peter St John Project architects Stephanie Webs, Adam Khan, Bernd Schmutz, James Payne, Kornelia Gysel, Kim Ah-ra, Sabine Rosenkranz, David Kohn Quantity surveyor Jackson Coles Structural, services and civil engineer Arup Project manager Hornagold & Hills Access consultant David Bonnet Associates Acoustic consultant Tim Lewers Acoustics Artist Nathan Coley Fire consultant Arup Fire IT consultant Jackson Kent Associates Security consultant Arup Security Theatre consultant Charcoalblue Form of contract JCT 98 Gross external floor area 3,400m 2Total cost ú11 million Start on site December 2006 Completion Spring 2008 CAD packages used Microstation
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Keywords: knowledge management, EAI, enterprise application integration, healthcare organisations, information systems, information integration, knowledge integration
Achieving knowledge management integration through EAI: a case study from healthcare sector
Healthcare Information Systems (IS) non-integrated nature is associated with inefficient data and knowledge exchange and reduction in healthcare care services' quality. Therefore, numerous medical errors occur that impact healthcare services. Healthcare organisations have used Enterprise Application Integration (EAI) to integrate IS. Literature indicates that EAI achieves integration at four layers namely: connectivity, transportation, transformation and process integration. We suggest that among others, EAI achieves Knowledge integration and propose a Revised Model for Integration Layers (REAL), tested through a case study. The results indicate that cases leading to medical errors and wrong prescription can be prevented by integrating knowledge through EAI.
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This article is a collaboration between MedPage Today® and:
ORLANDO -- Treatment of constipation in multiple sclerosis (MS) patients with lubiprostone increased spontaneous bowel movements but also appeared to induce diarrhea, according to a small trial reported here.
In a 21-patient randomized, double-blind, placebo-controlled study lasting 3 weeks, the rate of spontaneous bowel movements more than tripled in the 11 assigned to lubiprostone (P=0.04), but only when initial effects in three patients who discontinued early were assumed to have continued had they stayed in the trial, reported Cynthia Irish, RN, and colleagues at the University of Rochester in N.Y.
In analyses that handled the dropouts differently -- such as excluding them altogether or assuming that they had no spontaneous bowel movements after leaving the study -- lubiprostone showed only a weak advantage over placebo, according to the researchers' report at the joint meeting of the Consortium of Multiple Sclerosis Centers and the Americas Committee for Treatment and Research in Multiple Sclerosis.
The adverse events driving the three patients from the trial appeared to be diarrhea, suggesting that lubiprostone may have been too effective in these individuals.
Results from the analyses "would lead one to believe that lubiprostone was effective in increasing the number of spontaneous bowel movements at the price of an increase in diarrheic events," Irish and colleagues concluded.
Constipation is one of the many less-publicized effects of MS, affecting more than 40% of patients in one study. Whether conventional treatments for the condition are effective in MS patients remains unclear.
Lubiprostone (Amitiza) is FDA-approved for relieving chronic idiopathic constipation and opioid-induced constipation in adults as well as constipation-predominant irritable bowel syndrome (IBS) in women. The American College of Gastroenterology has recommended the drug for constipation associated with IBS.
However, as Irish and colleagues pointed out, the drug has not been evaluated for constipation arising from neurological disorders.
In their study, they recruited a total of 40 MS patients reporting chronic constipation. Of these, 19 were excluded, most because they had more than four spontaneous bowel movements during a 2-week washout period, when patients' previous constipation medications were stopped. Patients then received either placebo or 24 mcg of lubiprostone twice daily for 3 weeks.
Patients included in the trial represented a mix of MS types, including both relapsing and progressive forms. Their mean age was 45 and the mean duration of their MS was 14.5 years. The mean expanded disability status scale (EDSS) score was 5.2.
The placebo and lubiprostone groups were well balanced, except the mean age was about 6 years greater in the active-drug group.
Spontaneous bowel movements during the washout period averaged 3.4 in the lubiprostone group and 3.2 in the placebo group.
In the primary analysis, under which rates of spontaneous bowel movements seen in study dropouts prior to their withdrawal were assumed to continue through the entire 3-week treatment period, the rate grew to 6.2/week in the lubiprostone group compared with 2.6/week with placebo (P=0.04).
But the weekly rate with lubiprostone was only 3.7 in the eight patients continuing in the study for the full 3 weeks, and 3.1 in the three dropouts, who were assumed to have no more spontaneous bowel movements after leaving the study.
Two patients in the placebo group reported one diarrhea event each. In the lubiprostone group, five patients reported a single such event, two had two events, and one had eight events. The frequency was significantly greater in the lubiprostone group compared with controls (P=0.02).
Irish and colleagues also calculated scores on the Bowel Control Scale -- a patient-reported measure of overall bowel-related symptoms and quality of life -- and found nearly identical declines in both treatment arms.
The researchers interpreted this finding as an indication that increases in spontaneous bowel movements with lubiprostone were offset by the diarrhea events. Irish and colleagues argued that this conclusion was further supported by the finding that Bowel Control Scale scores did not increase in the three early dropouts.
"These adverse events did not heavily affect quality of life," they suggested.
The study was supported by Takeda.
Study authors reported no financial interests other than Takeda's research support.
- Reviewed by Robert Jasmer, MD Associate Clinical Professor of Medicine, University of California, San Francisco and Dorothy Caputo, MA, BSN, RN, Nurse Planner
last updated


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So you may have noticed I haven't been around much (here, on your blogs, on Twitter) for the past month. If you didn't notice, I'm sorry but I'm just too busy to get upset. That would have upset me two months ago since I have a need to be liked and missed and stuff. But now, as I said, I'm too busy.
About a month ago I got a new job. It's related to French-teaching, not writing, but it's the job I've been waiting for since my youngest son went to school full time. You know, the job I could feel good about. The job I could get passionate about. The job that didn't put my education and experience to waste.
On top of the new job, I'm still taking care of my kids and making sure they do their homework and feeding them when my husband is away and laundering their clothes. And stuff. Among the "and stuff" is the sweater I'm crocheting for A-Read. I'm currently on the second sleeve so it's almost done. But then I have to make a sweater for #2 son (gosh, I still don't have a suitable nickname for him).
And I'm still reading. Of course. I couldn't live without reading. And I'm still writing, but at a much slower pace than ever before.
I had started a new wip just before I got the new job and I'm still really excited about this new book. It's different than anything else I've ever written. The main character is more different from me than any other character I've ever written. I'm allowing it to happen in dribs and drabs for now, but I plan to do NaNo again this year. And I WILL finish the wip in November.
Yup. You heard it here.
So what have you all been up to in the past month? Tell me about all your wonderful projects, whether reading, writing, or crafty, or whatever. I'm hungry for your news.


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Meet The Team
Douglas L. Mason, CEO and Director
Douglas has served as a senior officer and director of a number of public companies and has extensive experience in financings and acquisitions in capital markets, raising over $200 million over the past 25 years. Douglas is currently Chairman of the Board and C.E.O. of Waterfront Capital Corporation, Canadian International Pharma Corp., International Bethlehem Mining Corp., and Rainy Mountain Royalty Corp. Douglas is also a director and the sole shareholder of Criterion Capital Corporation, a management consulting company, and Chairman and C.E.O. of Mooyah Canada Franchise Corp., a fast-casual "better burger" franchise in Canada. From 1988 through 2005, Douglas served as President & Chief Executive Officer and as a director of Clearly Canadian Beverage Corporation, a producer of premium beverage products. During his 20 years in the beverage industry, Douglas built a reputation for innovation and has been credited as being one of the pioneers of the New Age Beverage category. moc/puorgtnorfretaw//nosamd
Valerie Samson, Marketing/Corporate Services and Director
Over the past 25 years, Valerie has held Corporate Services, Marketing and Communications positions in the consumer brands, business advisory and exploration sectors, including Nabob Coffee Co., Clearly Canadian Beverage Corporation and a number of junior mineral exploration companies listed on the TSX Venture Exchange. moc/puorgtnorfretaw//nosmasv
Clive E. Shallow, Shareholder Communications
Having passed the Canadian Securities Course and RR Registration in 1985, Clive has accumulated a combined 28 years of experience in the Canadian securities sector, with particular concentration in the mining, tech and alternative beverage industries. Prior to joining the Waterfront Group of Companies, he held a 15 year position as Shareholder Communications with Clearly Canadian Beverage Corporation, a new age beverage company formerly inter listed on the TSX and NASDAQ. moc/puorgtnorfretaw//evilc
Sead Hamzagic, CGA, CFO and Director
Sead has over 25 years of public practice accounting and financial management experience with a variety of public and private companies. He is on the board of directors and Chief Financial Officer for a number of publicly trading companies and as a financial advisor for a number of privately held companies that form part of the conglomerate group of companies chaired by Douglas Mason. Sead is a member in good standing with the Certified General Accountants Association of British Columbia. moc/puorgtnorfretaw//daes
Andrzej Kowalski, Director
Andrzej is a successful entrepreneur and multiple business owner. He is also a qualified lawyer experienced in commercial law and litigation. Much of Andrzej's business career has involved founding, financing, operating and selling technology companies both in the private and public sectors. He also has experience with real estate development and investing. Andrzej holds Bachelor of Arts and Bachelor of Laws degrees from Monash University, Australia and a Master of Laws degree from The University of British Columbia. moc/puorgtnorfretaw//ikslawoka


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Weekend Kalamazoo Indoor Flea & Antique Market
January 13
Saturday 8:00 a.m. - 3:00 p.m.
Special Weekend Market! Come check out the market for some great deals and great merchandise! Choose from new and used items, antiques, handcrafted items, and much more! 75 Booths Available! For booth space call 269-383-8761 or visit www.kalamazooexpocenter.com


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| One-Minute Clinician
Pain and Hormones: Advances in Testing and Treatment
A number of factors have coalesced to make pain and hormones a topical issue in pain management. One is that there are enough scientific studies to show us that pain itself has a dramatic effort on the hormone system. It will deplete hormones, for example. We also have learned that you can't get good pain control unless the body has adequate levels of hormones, and sometimes the clinician will have to replace some of those hormones. There's also a group of hormones called neurohormones that have been discovered in the brain and that the brain uses them to protect itself and to heal its tissues and in certain pain states, we know that we're going to have to regrow nerves to get good healing.
A major complication of long-term opioid therapy is suppression of the hormonal systems. This means that we're going to have to test for, and replace hormones in practically every patient who takes opioids on a daily basis. Unfortunately, pain itself doesn't have a number, and in medicine we're used to measuring things by numbers. However, pain does cause effects on the hormone system or on inflammation that are measurable. Several markers have now been identified to help us, in effect, measure pain and we can't know whether there our therapy is effective if we're not measuring something objectively. There's another aspect to it and that is, these biomarkers also separate the drug user or the drug seeker away from the legitimate pain patient.


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Hand crafted from 100% organic cotton jersey in our studio at The Factory, this versatile kitchen accessory is perfect for keeping hands from heat and the heat from the table.
• Measures approximately 9" x 7"
• Wash gently + hang to dry
• Hand made to order in Alabama in our Building 14 production facility
• Ships within 2 weeks


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Stripes Inspiration, Birthday Celebration and a Free Quick Knit Pattern
You might have noticed my absence of the last weeks. I've been busy with work, knitting and Dutch classes too. So sorry and so many ideas to bring you today! I don't want to overwhelm you, though. First I'll show you... Continue reading →


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Yealink Skype for Business Phones
Yealink's Skype for Business phones deliver end-to-end unified communications solutions for Microsoft environments. With the UC Edition phones, users are able to extend their communication experience in a more collaborative environment.
With their high resolution displays both the T46GN and T48GN phones are equipped with a modern interface which enable users to enjoy familiar iconography and operation flows that reflect a true Skype for Business experience.


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It was a game of basketball with a difference. Replacing the squeal of sneakers on the court came the sound of clashing wheelchairs. With the cheers of about 30 teenagers from the sideline, the game was on in earnest. And as the students from Victoria University Secondary College in St Albans were finding out, this match wasn't so much about winning or losing, but more about the challenges of life using a wheelchair. The game was part of the Wheeltalk School Awareness Program.
The Wheeltalk School Awareness Program
The Wheeltalk School Awareness Program is an educational exercise run by Disability Sport and Recreation (DSR). The aim of the event is to raise awareness of disability and promote the benefits of a healthy lifestyle. The overall design of the program encourages people to think about diversity, disability and acceptance.
The Wheeltalk package is offered to community groups as well as primary and secondary schools. Each year the program reaches some 25,000 people. Sessions run for about 1.5 hours and include a verbal presentation by a DSR ambassador with a disability. This is followed by a series of wheelchair activities including basketball.
Workplace accident
In his address to the students Gary Connor, hand-cycling champion and DSR ambassador, talks about his workplace accident. And how at the age of 22 he fell and broke his back, leaving him with paraplegia.
He tells the students, "When I was your age, I never expected to end up in a wheelchair. But I did and I've had to make the most of it".
There is stunned silence as Gary describes the determination and mental strength it takes to rebuild your life after such an accident. He goes on to describe how that same determination and strength helps overcome many challenges; not only for the simple things in life we all take for granted, but sporting achievements as well.
Opening minds to disabilities
There are lots of questions. The students are mostly interested in Gary's initial barriers, his coping skills, marriage and family situation. Gary's talk installs a lot of interest and thinking by the students.
One of the students Nipa reflects on Gary's talk. "I've never thought much about disabilities before this. But this has opened my mind. Not just about how people with disabilities cope, but to everyday possibilities."
Talking about the barriers, another student Simote says, "Gary is able to demonstrate what most people don't see. And rather than complain about his disability, he just gets on with making the most of what he has".
Sharing an understanding
Seventeen year old Jasmine initiated Wheeltalk's school visit at St Albans. Recent work experience gave her insight to the challenges of those with disabilities. She wanted to share this understanding with others. Jasmine says it was her best project ever.
And about her experience on the court she says, "You've got no idea how hard it is in those wheelchairs trying to play basketball. Gary makes it look so easy".
But Gary says years of practise can make anything look easy. His overall message is that living with a disability is far from easy.
He again emphasises, "it's constant hard work that takes lots of determination and mental strength to achieve what most people take for granted".
Taking care
Gary goes on to encourage students to live life to the fullest. However, his motivation comes with a message to take care and be responsible.
The Wheeltalk Disability Program certainly makes people more aware. It also emphasises the dangers of risky behaviour and what can happen when things go wrong. And while showing the advantages of determination and mental strength, it also opens minds to differences, challenges and integration.


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Dr. Garvie-Loveland grew up in Portland and attended St. Mary's Academy. She earned her undergraduate degree from the University of Notre Dame. Medical school brought her to Dublin, Ireland where she attended University College Dublin School of Medicine. While in medical school, she earned the academic gold medal in obstetrics and gynecology from the Irish National Maternity hospital. She then returned to the U.S. to complete her residency at the University of Wisconsin in Madison, where she was appointed chief resident. While at the University of Wisconsin, Dr. Garvie-Loveland earned the Bayer resident teaching award, the Peckham teaching award and the AAGL award for excellence in laparoscopic surgical skills.
Dr Garvie-Loveland enjoys practicing obstetrics and gynecology because she enjoys the continuity of women's healthcare which incorporates both medical and surgical practices. She has a special interest in minimally invasive surgery, robotic surgery, family planning and perimenopausal health.
Dr. Garvie-Loveland is excited to return home to Portland and to the Pacific Northwest. In their spare time, Dr. Garvie-Loveland and her husband enjoy hiking, skiing, cooking and enjoying time with their golden retriever puppy.
Read Dr. Garvie-Loveland's articles in the Wellness Journal, a blog written by our providers on health topics for women of all ages >
Click here to get contact information or directions to one of our offices….
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My friends A. and R. with their daughters V. and A. were in town (or let's say in the state) and had rented a cottage at Damariscotta lake for a week. The weather was gorgeous for most of the time, allowing for paddling to the little sun deck in the lake with the canoe or getting canoe service by V., hanging out, catching up and getting a serious tan on the side. Lovely day!
R. had manage to catch some fish in the lake, and so there was dinner. A perch and a bass, carefully prepared and simply steamed by being wrapped in aluminum foil on the BBQ. With it came potatoes wrapped in foil and cooked in the camp fire with a charcoal crust and soft on the inside, sweet corn and steak. The setting could not be better: a lake view and sunset.


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Packages for Houston; a desktop dashboard for cloud server management.
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This is a wonderfully garlicky and nutty pesto. Without any bitterness that is sometimes found in greens. The recipe by Sunny Anderson uses kalamata olives. I didn't include them because I thought the brine flavor of the olives would be too much for the kids, but after reading reviews of similar recipes I am definitely going to add the olives next time I make this pesto.
Besides the wonderful flavor and numerous ways this pesto can be used, it is a a great recipe to make with kids. There is something kids of all ages can do. Older kids can do all of the steps, with the exception of cooking the greens. Younger ones they can get lots of practice cutting by rough cutting the greens and garlic before adding them to the food processor. And the really little ones always love pressing the buttons and watching the food go around in the food processor.
I got two meals out of this recipes. I used it one night on pasta and another night used it as a sauce for turkey meatball subs. Both dishes were simple, super flavorful and enjoyed by the big and little people of the house, which recently hasn't been happening very often.
Collard Green Pesto
Printer Ready
1 lb Collard greens (stems removed)
½ cup Almonds lightly toasted
2 cloves Garlic
1 cup Parmesan cheese
1 cup Olive Oil
Bring a large pot of salted water to a boil. Add greens and blanch for about 1 minute, or until bright green. Drain and shock in ice water bath. Remove from ice water and pat dry with paper towels. Roughly chop greens
Add greens, almonds, garlic and cheese to food processor. Process until ingredients become finely chopped, with processor running begin adding olive oil until a paste is formed and pesto comes together.


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Pharmaceutical Patent Litigation Settlements: Implications for Competition and Innovation
Publication Date: November 2006
Publisher(s): Library of Congress. Congressional Research Service
Series: RL33717
Topic: Law and ethics (Intellectual property, copyright, patent, and trademark law)
Manufacturing and industry (Pharmaceutical industry)
Although brand-name pharmaceutical companies routinely procure patents on their innovative medications, such rights are not self-enforcing. Brand-name firms that wish to enforce their patents against generic competitors must commence litigation in the federal courts. Such litigation ordinarily terminates in either a judgment of infringement, which typically blocks generic competition until such time as the patent expires, or a judgment that the patent is invalid or not infringed, which typically opens the market to generic entry.
As with other sorts of commercial litigation, however, the parties to pharmaceutical patent litigation may choose to settle their case. Certain of these settlements have called for the generic firm to neither challenge the brand-name company's patents nor sell a generic version of the patented drug for a period of time. In exchange, the brand-name drug company agrees to compensate the generic firm, often with substantial monetary payments over a number of years. Because the payment flows counterintuitively, from the patent proprietor to the accused infringer, this compensation has been termed a "reverse" payment.
Commentators have differed markedly in their views of reverse payment settlements. Some observers believe that they are a consequence of the specialized patent litigation procedures established by the Hatch-Waxman Act. Others have concluded that when one competitor pays another not to market its product, such a settlement is anti-competitive and a violation of the antitrust laws.
Since 2003, Congress has required that litigants notify federal antitrust authorities of their pharmaceutical patent settlements. That legislation did not dictate substantive standards for assessing the validity of these agreements under the antitrust law, however. That determination was left to judicial application of general antitrust principles. Facing different factual patterns, some courts have concluded that a particular reverse payment settlement constituted an antitrust violation, while others have upheld the agreement.
Congress possesses a number of alternatives for addressing reverse payment settlements. One possibility is to await further judicial developments. Another option is to regulate the settlement of pharmaceutical patent litigation in some manner. For example, one proposal would declare that certain reverse payment settlements constitute acts of unfair competition. Legislation could also establish a presumption of either legality or illegality under the antitrust laws, along with consideration of relevant factors to be weighed by the courts.
This report will be updated as needed.


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Thursday, December 16, 2010
Gift bag
Here is my entry for Polka Doodles week 49 challenge - Project to hold a gift.
I took a small brown paper bag and covered it on both sides with paper from the DCWV Stack 6. I cut a topper for my bag using Penny Duncan's 4 point 6 scallop nesting mat. I stamped my nephew's name with some hero arts letter stamps in white ink and colored it in with some prismacolor pencils.
I put the gift inside (not telling what it is, just in case my nephew looks at my blog!). I folded the topper in half and put it on the top of the bag and punched two holes through the topper and the bag. I attached some silver eyelets in the front and the back of the topper. I then threaded some ribbon and tied it all shut with a bow :)
Here is the link to the challenge:
Polka Doodles
9 comments:
- Audrey said...
What a lovley gift bag. Thanks for joining us at Polka Doodles.
- December 16, 2010 at 4:56 PM
- Colette said...
Very nice, clean and simple gift bag, ideal for a male recipient, glad you could join us at Polkadoodles this week, Good Luck
Colette xxd
- December 17, 2010 at 1:53 AM
- Saskia said...
Beautiful gift bag, very elegant!
Lovely to see your work at Polkadoodles Challenge, thanks!!!
Saskia :)
- December 18, 2010 at 2:19 AM
- Tip Top said...
Do like the paper! Thanks for entering the Polkadoodle Challenge - hope you can join us again next week!
- December 19, 2010 at 8:44 AM
- FauxPainter - Dee Paramour said...
Beautiful. Thanks for taking part in the Polka Doodles challenge.
- December 19, 2010 at 11:51 AM
- Fliss said...
Really great bag and lovely for men and boys.
Thanks for joining in with Polka Doodles Gift Holder challenge and look forward to seeing more of your creations.
PS: I was intrigued by your name as my elder daughter is a big fan of Manga!
- December 19, 2010 at 12:04 PM
- Jenny said...
Really lovely gift bag! Thanks so much for sharing with us over at Polka Doodles this week.
- December 20, 2010 at 1:49 PM
- Claire Phillips said...
Thanks for playing along at Polkadoodles this week! What a fab gift bag! Cheers Claire x
- December 21, 2010 at 12:25 AM
- BondGirl said...
great project. thanks for joining in the polkadoodle challenge
- December 21, 2010 at 2:12 AM


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Apple and Ale Chutney
Our Apple and Ale Chutney is packed with local apples, dried fruit & great local ale. It's perfect with a chunk of cheese & crusty bread.
Ingredients: Apples 24%, dried fruits - raisins, dates & apricots (sulphur dioxide), sultanas, currants, onions, Aspall's cider vinegar, ale 10% (barley, hops & yeast),
brown sugar, lemon juice & spices.
Allergen advice: Please see ingredients list, all of our products are produced in a kitchen where nuts & mustard are used.
Weight: 205g