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Molecules 2015, 20(10), 17684-17719; https://doi.org/10.3390/molecules201017684
Anti-Diabetic Potential of Noni: The Yin and the Yang
Laboratory of Metabolic Disorders and Alternative Medicine, Department of Molecular Biosciences and Bioengineering, College of Tropical Agriculture and Human Resources, University of Hawaii at Manoa, Honolulu, HI 96822, USA
Author to whom correspondence should be addressed.
Academic Editor: Maurizio Battino
Received: 3 May 2015 / Revised: 3 September 2015 / Accepted: 16 September 2015 / Published: 25 September 2015
(This article belongs to the Special Issue 20th Anniversary of Molecules—Recent Advances in Natural Products)
AbstractEscalating trends of chronic diseases such as type-2 diabetes (T2D) have sparked a renewed interest in complementary and alternative medicine, including herbal products. Morinda citrifolia (noni) has been used for centuries by Pacific Islanders to treat various ailments. Commercial noni fruit juice has been marketed as a dietary supplement since 1996. In 2003, the European Commission approved Tahitian noni juice as a novel food by the Health and Consumer Protection Directorate General. Among noni's several health benefits, others and we have demonstrated the anti-diabetic effects of fermented noni fruit juice in animal models. Unfortunately, noni's exciting journey from Polynesian medicine to the research bench does not reach its final destination of successful clinical outcomes when translated into commercial products. Noni products are perceived to be safe due to their "natural" origin. However, inadequate evidence regarding bioactive compounds, molecular targets, mechanism of action, pharmacokinetics, long-term safety, effective dosages, and/or unanticipated side effects are major roadblocks to successful translation "from bench side to bedside". In this review we summarize the anti-diabetic potential of noni, differences between traditional and modern use of noni, along with beneficial clinical studies of noni products and challenges in clinical translation of noni's health benefits. View Full-Text
Keywords: Morinda citrifolia; noni; Tahitian noni juice; type 2 diabetes; herbal products; alternative medicine
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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MDPI and ACS Style
Nerurkar, P.V.; Hwang, P.W.; Saksa, E. Anti-Diabetic Potential of Noni: The Yin and the Yang. Molecules 2015, 20, 17684-17719.
AMA Style
Nerurkar PV, Hwang PW, Saksa E. Anti-Diabetic Potential of Noni: The Yin and the Yang. Molecules. 2015; 20(10):17684-17719.Chicago/Turabian Style
Nerurkar, Pratibha V.; Hwang, Phoebe W.; Saksa, Erik. 2015. "Anti-Diabetic Potential of Noni: The Yin and the Yang." Molecules 20, no. 10: 17684-17719.
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What Is A Network Marketing Business Online Business ?
The Multilevel Marketing Network is a system of marketing goods or services, which uses one of the most effective forms of advertising, word of mouth promotion. With this system, the business rather than spending large amounts of money on traditional advertising, pay commissions to independent distributors (affiliates) for referring the products. With this system, companies gain more customers, and we'll give people like you and me, the opportunity to develop their own business with big advantages over other traditional business models, some of these advantages are as follows: – There are no schedules. – You can do business from anywhere. – The investment is very low compared with other traditional business – the risk is low. – No need to create your own products. – No need to hire employees.
In addition, companies that offer this kind of business, you usually offer training to be able to develop business in the best way, and also acquire very good skills for business, which undoubtedly will be of great help to give some more ambitious step in the future …. and well, obviously apart from the advantages already mentioned, is the main income, these businesses can generate excellent revenue, several thousand dollars a month, in many cases above what you could win with some small and medium traditional business . As you can see, this kind of business are an excellent alternative for people looking to generate extra income to improve their lifestyle, without having to make major investments or take big risks. Many people confuse multilevel business with the pyramids, but there are significant differences. In the pyramids or chain, there is no legal product or service is sold, or a solid company to back it up correctly formulated as multilevel business. In the pyramids, there comes a time when the entire array collapses as it is not supported only by the admission of new members, in the pyramids, people who are at the top always win much more than that are below or join after the alleged business. In contrast, multilevel business all have the same chance of winning, because we all have the same levels of profits, which both can grow these levels depends on our effort and perseverance, and as long as we are in a solid company, our monthly income for life will be.
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subset: commoncrawl


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As noted in several of my "more recent" posts, I've been struggling quite a lot with the transition out of the home-renovation stage -- more than eight months of intensive work, almost exclusively on our house (save for a few conference presentations and one teaching opportunity), which I had no time or spare energy to blog about so had to content myself with posting pics on Facebook -- and into the next chapter, In Which I Find Work That Results in a Paycheck. I have applied to everything from university presses, sessional teaching jobs and nonprofits on the one hand, to CostCo, Rona, Lowe's and local coffee shops on the other. I still believe I will find work, soon, possibly even work that utilizes some of my best vocational skills. And I haven't exactly been idle in the interim, either: I've done lots more little things for the house and assembled a book proposal, too. But the Waiting remains frustrating.
Not that the Father of the heavenly lights hasn't continued to give good gifts (James 1:17) along the way. Just yesterday, as I explained Karen's and my vision and purpose for the house at the request of a friend and colleague who will be blogging about us soon, one of his questions nudged me in such a way as to consider this Waiting in a slightly different way. Now, Karen and I have been careful to acknowledge that the founding of a house for spiritual direction and retreat doesn't mean that we've mastered related disciplines like silence, solitude, or sabbath-keeping; far from it! No, we've insisted, opening this house will require us to grow in these things in order to model and teach them to our guests. But even once we'd acknowledged that, it took Jim's questions yesterday to make me realize anew that those who would claim to model disciplines must often first be disciplined, both in the active sense (self-discipline) and the passive (being chastened -- but let's not digress here into a full discussion of what that looks like in the biblical tradition!). That is, it's almost as if God has us going through a time of re-learning certain disciplines -- in addition to the two years of similar experience, leading up to the envisioning of Lectio House -- before (not just at the same time as) we model them for others.
So the Waiting isn't necessarily any easier. But it's a gift (a small one, he grumbled semi-gratefully) to know that what has felt like the psalmist's valley of the shadow of death will, with enough perspective, be only the shadow of discipline -- a dark place, yes, but one in which the light can still sometimes break through.


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American Typewriter ITCW01LtIt Fonts
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Unispace W00 Bold Italic
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Got That Bling NF W01 Regular
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DS Weiss-Gotisch Alt
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text:
Newbie from Lancashire
Hi All,
New to the forum but not to Dukes, I've had a '98 ST2 a couple of years. I've been riding over thirty five years.
I'm an active member of the FJ/FJR Owners Club attending as many runs as possible with the Wife. (I own an FJR AE and I restored an FJ1200 3XW a couple of years ago).
It (ST2) had sat in my Dads workshop for many a year as he prefers twins of the flat variety.
Well it was pretty useless as a working motorbike when I went to pick it up, although immaculate to look at it was plagued with electrical issues, needed a belt change and an MOT.
Solenoid, battery leads and the correct battery for the single phase genny and it was put right.
Next I thought I'd look for some more "go" so some nice carbon pipes, DP performance EPROM and air filter got it just right.
Bar risers, Zero G screen and a Corbin seat sorted the comfort.
It's now a brilliant all round bike, in fact I enjoyed riding that much I picked up an ST3 too (which I've just broke the RHS handlebar clamp on) Grrrrrrrr.
Always loved Italian bikes as a kid but my Dad wouldn't entertain 'em.
I will be looking for a Multistrada in a couple of years when it's time to move on my FJR AE.
So I'd just like to say "hello All"!
Newbie form Lancashire 2
hello all sold my 600ss and replaced with a Ducati 749 here's to some spreading of thoughts and knowledge,
Well done!
Always nice to hear of another ST being restored to roadworthy.
The Buell owners club / Italian event at Spillsby might be a short run out for you, Oct, I believe.
Is that you Rod?
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I thought it was a very good game too by both players.
But as for Martin's best game? Well, being picky I thought that 983 was pretty gettable to be honest!
A group for contestants and lovers of the Channel 4 game show 'Countdown'.
I thought it was a very good game too by both players.
I will watch that, but I can wait.Marc Meakin wrote: ↑Sat Dec 08, 2018 5:09 pmMy missus just got the Christmas TV guide and just to give those interested the heads up that a Young Offenders chrsitmas Special is on BBC one at 11.15 pm 23rd December.
Can't wait
Hard toffee is rubbish though.Thomas Carey wrote: ↑Fri Dec 07, 2018 5:17 pm^^. Eclairs are fine if that's what you want but it's a chocolate selection box thing so generally you don't.Gavin Chipper wrote: ↑Fri Dec 07, 2018 3:03 pmLooking at the general rating of Bounty, I think having Bounty as your worst thing is a good problem to have. Heroes have Eclairs...
Because you still see that a thread exists without having to go into it or even into the spoilers section generally.Zarte Siempre wrote: ↑Thu Dec 06, 2018 4:05 pm*shrug* It's a Spoilers section, who cares?
Eat some chocolate then. You can get vegan chocolate.Matt Morrison wrote: ↑Thu Dec 06, 2018 12:34 pmHaha I haven't missed chocolate this much in ages actually.
Yeah, it is a bit odd. They're perfectly fine.Marc Meakin wrote: ↑Thu Dec 06, 2018 3:51 pmWhy so much hate for the Bounty.
It's my no 1 choice......feel free to post me yours if you hate them so much.
You can do that here.Matt Morrison wrote: ↑Wed Dec 05, 2018 6:40 pmNot answering as I was prepared to rank bar mitzvahs and half-birthday parties.
This has been mentioned in previous series as well!David Williams wrote: ↑Wed Dec 05, 2018 8:29 pmThe existence of this thread before the preliminaries are over is itself a spoiler.
I'm just amazed that people still miss HOMAGE and go for IMAGE. Do they not learn?Fred Mumford wrote: ↑Wed Nov 28, 2018 6:49 pmWhy do so many people insist on pronouncing HOMAGE as if they are pretentious or French? It's "hommidge" ffs.
But it doesn't seem to be "live" any more so it's time to post the solutions!Thomas Carey wrote: ↑Sat Nov 24, 2018 7:32 pmsolve the conundrums, read the op and find outGavin Chipper wrote: ↑Sat Nov 24, 2018 7:40 amWhat is the opinion?Thomas Carey wrote: ↑Sun Nov 18, 2018 10:18 amyeah, nice one Toby, got the opinion (lmao) but missed a few of the cons, literally just swap the last 4 letters on the one you missed
What is the opinion?Thomas Carey wrote: ↑Sun Nov 18, 2018 10:18 amyeah, nice one Toby, got the opinion (lmao) but missed a few of the cons, literally just swap the last 4 letters on the one you missed
Dunno. But it can happen. It also depends on how you define crying - does it have to be full on streaming tears or does a bit of welling up in the eyes that doesn't make it down your face count?Marc Meakin wrote: ↑Wed Nov 21, 2018 6:57 pmThe question to ask Gavin is when was the last time you cried ?
Cos onion goggles are a thing.Marc Meakin wrote: ↑Wed Nov 21, 2018 4:55 amSome more from me
Tumble Drier
Onion Goggles
Garlic press
I don't think either of these is rare. Certainly most people don't have tattoos. And it might depend on how you define jewellery. E.g. I have medals from running events. Do I therefore own jewellery?Marc Meakin wrote: ↑Thu Nov 15, 2018 4:35 pmI want to add Jewellery of any sort.
Also no tattoos, not sure if you 'own ' them though
Matt Morrison wrote: ↑Tue Nov 13, 2018 6:47 pmThought you meant Ashwin Shah for a minute.
You did make a brief comeback in 2016 though.M. George Quinn wrote: ↑Thu Nov 08, 2018 8:17 amYusss! I've spent 10 years off the forum, too. Just to be on the safe side.


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text:
Greystones resident Jim is Oxfam's ever-optimistic chief executive
David Medcalf talked to Oxfam's CEO Jim Clarken about the quest to end the inequality that allows half of the world's wealth to remain in the hands of an elite one per cent
First of all, apologies to the proprietors of The Burnaby pub, where this interview took place. The venue in the centre of Greystones nominated by Jim Clarken proved most congenial for the purpose. However, so intense was the conversation that neither Jim nor his interrogator ever quite got around to ordering a drink during the hour it took to complete our business.
Intense is certainly the word to describe the chief executive of Oxfam, a man needs no encouragement to speak about his chosen cause. He does so with a rapidity and a fluency which suggest that he has the facts and the lines of argument forever at his fingertips. Yet the intensity and the conviction which underpin the flow of sweet reason never shades into intimidation or pleading.
His is a long term project which relies on the drip-drip of steady persuasion rather than any verbal battering ram. An hour in his good-humoured company and you may emerge a few steps closer to being convinced that the world could be a better place. That is to say that all the world could be a better place, not just Greystones, not just Ireland, not just the West. Jim's perspective stretches to embrace the workers making trainers in Vietnamese factories and women struggling to feed families in rural Tanzania.
The Friday night crowd swelled in The Burnaby and noise levels rose as customers - the paying customers - greeted pals and reviewed the week's work. It is safe to assume that none of them commenced their chat by saying that they could speak for hours, if necessary, on the Democratic Republic of Congo, as Jim Clarken did. He was also probably the only one present in the pub who can state in truth that he has met Angela Merkel, the German Chancellor, while addressing high powered committees of the United Nations.
Oxfam, founded in 1942 at the height of World War Two, was concieved in England - the original title was Oxford Famine Relief. It persuaded Churchill's establishment that food should be dispatched from the ration-bound UK to deal with a famine in Greece. It seems that the organisation has always been not only a practical provider of support to those who need it most but also always ready with a telling word in the ear of those with power.
Now 76 years later, Oxfam Ireland is one part of Oxfam International, the body of which the Irish CEO is a director. Hence his familiarity with Frau Merkel and the inner workings of the United Nations in New York. The Irish operation stretches to 45 charity shops scatted across the island north and south, as well as other fundraisers.
Most of the work on the ground is carried out by 2,000-plus volunteers though there are also close to 200 paid employees.
The retail network includes Oxfam outlets in Wicklow Town and Bray: 'both very important contributors to the organisation,' as Jim is quick to point out. The shops, with their turnover of €18 million each year, are ultimately his responsibility as head of staff. However, it is quickly clear when talking to him that it is Oxfam's international programme which takes up most of his time and his nervous energy.
Oxfam has a presence of one sort or another in more than 90 countries and pays the wages of at least 10,000 staff, most of them in places far removed from Ireland. One way or another, their task is to improve the lot of people in the Developing World - please note that the term Third World is now considered obsolete. Sometimes, the work is a direct response to an immediate crisis.
Today it so happens that the plight of Rohingya refugees fleeing Burma in poverty stricken Bangladesh happens is top of his list. The job of Jim's colleagues on the ground is to ensure that these displaced people have food and clean water, in order to keep starvation and typhoid at bay in a place called Cox's Bazaar.
'We have built water systems there which cater for 200,000 people - that's equivalent to the population of an Irish city - in a space of weeks. We will stay as long as we are needed.' That list of his is a long one, which stretches to at least 30 crisis hit trouble spots around the world, though most of the rest not as high profile as the Burmese/Bangladeshi upheaval.
Jim reckons that within hours of last year's typhoon in Nepal for instance, Oxfam was busy repairing the damage done after the alarm was raised by personnel on the spot. He explains how the local workers were able to provide indications of what was required although they were present, not to deal with any such emergency, but to promote women's rights and fair conditions for labour.
Which brings us to his knowledge of the DRC - Democratic Republic of Congo - a source of continual concern to those who care about man's repeated inhumanity to man. 'There is life saving work to be done in the DRC all the time because of ongoing conflict,' he says of Africa's most enduring problem state.
Elsewhere, Oxfam's efforts are effected in programmes that are less dramatic and longer term in their intent. The Irish chief executive is an occasional visitor to Tanzania in Africa where the advances made are generally achieved far from the glare of publicity.
There, the guiding principle of development is to find out from people exactly what it is that they need to make their lives better.
A string of global issues bubble up in the course of dealing with local problems, among them climate change, economic inequality, land use, access to education and the availability of health services. He has formed the view that many of these will only be worked through once women are treated with proper respect.
'If you can deliver on women's rights, then you will solve a lot of the world's poverty problems,' he muses. One of his heroes is a Tanzanian lady called Manda whom he rates as one of the most inspiring people he has ever met, thanks to her leadership of the local women's movement.
She helps encourage more girls go to school, a first step to equality and improved life expectancy in one of the world's poorest countries. Similar initiatives in Rwanda, Malawi, Zambia and elsewhere are hauling communities out of extreme deprivation.
Man-made inequality and man-made inequality are phenomena that can be changed and Oxfam adopts a role in advocating such change. When someone buys a Christmas card or a second-hand dress in an Oxfam shop, they contribute to that.
'I am an optimist - you have to be in this business,' Jim muses, looking at a planet in which 800,000 people are blighted by extreme poverty, with less than a couple of dollars a day at their disposal. The optimist believes that there are solutions, though no overnight miracle cures.
He points to how multi-national companies could put a dent in that figure of 800,000 in need if only they would pay just a little more tax in the countries where they make their trainers or their garments for Developed World customers.
He reasons that the billion citizens of the world who go to bed hungry each night are balanced by the billion suffering obesity - in other words, there is no global food shortage, just a challenge of fair distribution.
Jim Clarken, now happily resident in Greystones, is a native of Limerick, brought up in small town Askeaton and educated by the Jesuits. He moved with doctor wife Dee, who works in the town as a GP, to Greystones three years ago and they are happily bringing their two children there.
The 47 year old remains proud to wear his Munster rugby jersey in County Wicklow, though his own achievements as a teenager were more in athletics a track and field than on the rugby pitch. Son of an industrial chemist, he graduated in commerce from University College Galway.
Work managing manufacturing plastics in Clonakilty and steel in Waterford was the logical next step. However, he always had an interest from a young age in world development, perhaps influenced by a child minder who was always looking to help the 'little black babies' - very un-PC but nonetheless heartfelt.
He worked with the Simon Community while in college and talks of how it never made sense to him that children could die of hunger. Eventually he quit the steel firm and went to South Sudan with a Goal emergency response team, supervising health care and water provision for 300,000 scared refugees living in mud huts.
His year in war torn Sudan was life changing, returning to Ireland in 2007 unable to see himself going back into business. When the Oxfam chief position came up shortly afterwards , he was ready to persuade the organisation that he was the man for the job and he retains the conviction to this day.
Bray People


text:
LG Electronics And PTO Today Applaud Youth Leaders For Energy-Saving Efforts
Primary tabs
LG Electronics And PTO Today Applaud Youth Leaders For Energy-Saving Efforts
NEWSROOM: LG Electronics USA, Inc.
CAMPAIGN: LG Energy Efficiency
CONTENT: Press Release
WASHINGTON, June 12, 2013 /3BL Media/ – LG Electronics USA and PTO Today – an organization serving parent-teacher groups from schools across the country – announced the 20 winners of the spring 2013 "Team ENERGY STAR" challenge. The organizations teamed up this year to recognize those youth who have gone above and beyond in their efforts to save energy and protect the climate.
Team ENERGY STAR, a multi-year initiative from EPA's ENERGY STAR program, teaches kids how to save energy and help protect the climate with fun educational activities and energy-saving actions they can do at home with their families. This year, the campaign incorporates characters from 20th Century Fox's new movie, EPIC – released in theaters May 24 – to help inspire young people and teach them about energy and the environment in an interactive and engaging way.
The spring 2013 challenge invited the youth community to join Team ENERGY STAR and take the "EPIC pledge" to save energy at home. After taking the pledge, kids were encouraged to share their energy-saving stories for a chance to win cool prizes from LG Electronics and Fox. More than 7,600 young people have joined this year's campaign, which launched during Earth Week, and more than 12,000 have joined since the campaign's inception in 2012.
"LG is committed to enhancing the quality of life for its consumers and creating a healthier and cleaner environment for current and future generations," said James Fishler, senior vice president of marketing for LG Electronics USA. "Through the Team ENERGY STAR campaign, we're honored to recognize and reward children who are helping save the planet by making small changes in their everyday actions and setting an example for their peers."
"We're so excited to see young people engaged in saving energy at home with their families," said Jill Vohr, director of marketing for the EPA's ENERGY STAR Labeling Branch. "The stories we received demonstrate not only an understanding of the importance of saving energy – particularly for the environment – but also that educating kids about protecting our climate is a good investment in the future health of our planet."
"PTO Today is proud to partner with Team ENERGY STAR in an effort to bring families together to learn what we can all do to help to make our planet a better place to live," says PTO Today founder Tim Sullivan. "We're excited to join with Team ENERGY STAR and LG in recognizing those kids across America who have made a concerted effort in their own school communities to bring attention to this important issue."
The Spring Team ENERGY STAR challenge ran from Earth Week through May 31, with more than 1,000 youth sharing their energy-saving stories. Entries were judged by EPA ENERGY STAR officials based on their energy-saving ideas, as well as creativity and ingenuity.
Winners of the Team ENERGY STAR challenge are being awarded a total of 25 prizes from LG Electronics, ranging from LG ENERGY STAR certified LED/LCD flat-screen HDTVs and LG ENERGY STAR certified LED Monitors to LG Android smartphones and feature phones, to LG wireless speaker docks.
The following top winners each will be able to select two LG prizes of their choice from the prizes mentioned above. They are also being featured on LG's electronic billboard in New York's Times Square.
- Teagan TR., Chevy Chase, Md.
- Kamren M., Moreland Hills, Ohio
- Deklan B., Dublin, Ohio
- Imelia G., Oak Ridge, Tenn.
- Isaac S., Wichita, Kan.
A second 2013 Team ENERGY STAR challenge featuring EPIC is planned for the fall when kids will have a chance to win another 25 prizes from LG Electronics USA.
Team ENERGY STAR is part of the multi-year, EPA campaign, "Change the World, Start with ENERGY STAR," developed to engage Americans of all ages in saving energy, money and protecting the environment with ENERGY STAR. If every American household took part in the Change the World, Start with ENERGY STAR Pledge, the nation would save more than 130 billion kilowatt-hours per year of electricity, save $23 billion in annual energy costs, and prevent greenhouse gases equivalent to the emissions from 21 million cars.
About ENERGY STAR
ENERGY STAR is a program of the U.S. Environmental Protection Agency helping us save money and protect the environment through energy-efficient products and practices. Now in its 20th year, ENERGY STAR has more than 18,000 partners committed to improving the energy efficiency of products, homes, buildings and businesses, and the ENERGY STAR label can be found on more than 65 product categories. In 2012 alone, Americans, with the help of ENERGY STAR, saved enough energy to avoid greenhouse gas emissions equivalent to those from 50 million cars — all while saving $24 billion on their utility bills.
About PTO Today
Since 1999, PTO Today has been connecting with and serving PTO and PTA leaders and school families at schools across the country through a broad variety of print, online and in-person resources all aimed at fostering greater parent involvement in schools. A division of School Family Media, Inc., PTO Today's services include PTO Today magazine, more than a dozen "PTO Expo" conferences around the country, and the School Family Nights® series of parent involvement events. Learn more at www.schoolfamilymedia.com and www.ptotoday.com. For more information about Go Green Night, please visit www.schoolfamilynights.com.
About LG Electronics USA
LG Electronics USA, Inc., based in Englewood Cliffs, N.J., is the North American subsidiary of LG Electronics, Inc., a $45 billion global force and technology leader in consumer electronics, home appliances and mobile communications. LG Electronics, a proud 2013 ENERGY STAR Partner of the Year, sells a range of stylish and innovative home entertainment products, mobile phones, home appliances, commercial displays, air conditioning systems and solar energy solutions in the United States, all under LG's "Life's Good" marketing theme. For more information, please visit www.lg.com.


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Samsung made its next move in its ongoing patent infringement fight with Apple by filing an appeal in hopes of getting everything from Apple's 2014 win in their second case overturned. The electronics maker is pushing to get the US$119 million Apple was awarded tossed out, and is working to block Apple's efforts to get a retrial in the case.
Samsung appeals everything is second patent infringement case with Apple
This second patent infringement case was similar in the first the two fought in that they accused each other of using each other's mobile device patents without licensing. In both cases, Apple came out the victor, although in the second case that win wasn't nearly the landslide it saw in the first where the court ordered Samsung to pay $900,000 in damages. Samsung vowed to appeal Apple's victory and is now following through.
Samsung wants to avoid a retrial because that would turn into a gamble where it could end up with a far worse result than it saw last year.
"Samsung still doesn't want a new damages trial on Apple's patents," said Florian Mueller of FOSS Patents. "For a jury that reached a decision on Apple's home turf, despite statistics that U.S. juries tend to favor U.S. companies over foreign rivals to a far greater extent than U.S. judges do, this was a really good outcome for Samsung and a retrial would come with a risk of a greater damages award that seems considerably bigger than the opportunity for Samsung to reduce the amount on retrial."
Apple's first request for a retrial was denied last year, but that doesn't mean the iPhone and iPad maker can't keep trying.
While both companies are pushing for the outcomes they'd prefer in this case, they have scaled back their extended patent fight in other ways. The jointly dropped their infringement cases against each other outside of the U.S. last year, and are now focusing on their appeals in both in-country trials.
Samsung targeted Apple's "quick links" patent '647 as part of its appeal saying the smartphones and tablets it makes don't use key parts of Apple's design in the way they they link actions and data structures. If Samsung can sway the court, Apple would lose out on most of the damages it was awarded in the second case.
Along with the quick links patent, Samsung is also working to get Apple's slide to unlock, autocomplete, synchronization, and unified search patents invalidated.
For Samsung, following the appeals path has a higher likelihood of working out in its favor than rehashing the trial. For Apple, a retrial opens up the possibility of a better damages award. "In order to get a more significant win out of this second California case, Apple would need the appeals court to order a new trial," Mr. Mueller said.
Both sides clearly want to change last year's verdict into something that serves them better, and need need to follow very different strategies to reach their goals. With Samsung's new appeal in the court's hands both companies will be working hard to get what they want, which ultimately is in the Appeals Court's hands.


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September 23, 2008
Botanical Gardens
After visiting the boat on Friday we went to see the Seattle Locks. Access to the Locks is through a botanical garden and I simply could not resist taking some pictures of the pretty flowers.
I always think that Foxglove looks like little
fairy hats.
I wish I could post smells on this blog because this
rose smelled so sweet and strong.
Hydrangeas are one of my favorite flowers.
I love how delicate the colors are.
I think this is as Passionflower?
Ok, this isn't from the botanical gardens, it is just
an old picture to celebrate the beginning of fall!
Happy first day of fall yesterday!
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And President Trump is making America great again". "A respected Supreme Court justice: Confirmed". Barely 100 days into President Trump's first term, his campaign has already launched a television ad seeking to the lay the groundwork for a second one.
Inside the ballroom, storied journalists celebrated the first amendment as President Donald Trump rocked a patriotic rally in Pennsylvania to mark his 100th day in office. The annual event is a tongue-in-cheek night that usually sees the sitting president sit back and have a laugh at his own expense before giving his own speech making fun of the media and himself.
But she said she never knew if McGahn or his team saw source material about Flynn because by that time she had been fired. Yates also said her decision to notify the White House counsel had been discussed "at great length". And she made it perfectly clear that it was because of legitimate concerns that the Russians had proof that the national security adviser was lying.
Councillors Stocks said: "As far I'm concerned we won the election in North Lanarkshire and it is our right to try to form the next administration". In a series of eyebrow-raising results, the Tories also won a seat in Cowdenbeath, where previous year the UK's last elected Communist stood down, and even in Ravenscraig.
Firing exchanges continued for almost an hour, the defence sources said. In April, Pakistan has committed six ceasefire violations. A woman was killed and her husband was injured in the ceasefire violation. The Jammu and Kashmir government has ordered the closure of all schools within 2km of the Line of Control in Rajouri district. The Home Ministry has reportedly said that in 2015 and 2016, incidents of ceasefire violation by Pakistan have been a daily affair in which 23 security ...
President Muhammadu Buhari will receive the girls on Sunday in the capital Abuja, it said, without saying how many Boko Haram suspects had been exchanged or disclosing other details. "We'd like to point out that they're among thousands of victims of Boko Haram and its offshoot, ISIS West Africa", Holt said. She said "I am happy where I am".
National Australia Bank Ltd. A 6.2 billion AU dollar (4.56 billion USA dollar) levy on the big banks, new taxes aimed at foreign investors who purchase Australian property and tax breaks for both small businesses and first-home buyers were the highlights of Morrison's address to Parliament overnight, in a package Prime Minister Malcolm Turnbull described as "fair on every level".
This followed on a report released last month, which revised earlier 1.1% and 1.2% growth forecasts for 2017 and 2018, respectively, to a forecast of 1.4% per annum in the same period. Growth in Eastern Europe and the Caucasus as a whole is expected to turn positive in 2017 after last year's stagnation. In the spring forecast, released in April, the National Prognosis Commission (CNP) has kept its economic growth estimate for this year at 5.2 pct.
Be sure to check out the new red-band trailer above, and let us know your thoughts on what you just watched by leaving a comment down below in the comments section. The R-rated reboot of the TV classic sees the Avengers of the beach, as they've been dubbed, banding together to take on Victoria Leeds (Priyanka Chopra), who threatens to destroy their home turf.
However, the prime minister also mentioned that the number of countries supporting the biannual anti-Israel resolution at UNESCO had dropped. Sweden was the only European country that voted in favor of the resolution, which disputed Israeli sovereignty over Jerusalem and harshly criticized the Jewish state for several projects in the capital and Hebron and condemned its naval blockade of Gaza.
The two parties are traditional rivals but have governed Austria together for the past decade, and for much of the time since World War II. Austria's far-right Freedom Party has led recent opinion polls, and came close previous year to having its candidate elected as Austrian president.
Hours before Monday's Senate hearing, Trump insinuated that Yates had leaked information on Flynn to the media. That means Spicer will not be the one to address the many questions surrounding Trump's firing of FBI Director James Comey , as well as the FBI investigation into potential ties between the Trump campaign and Russian Federation.
Accordingly to ISPR's Twitter post stands withdrawn and has become in fructuous. The withdrawal of the tweet could mean the two power centres have arrived at a settlement on the issue that had also led to action being taken against Rao Tehsin Ali, the principal information officer of the Ministry of Information.
The court has given Parwaz's lawyer a 10-day deadline to challenge the refusal to prosecute Adityanath in the Gorakhpur riots case. The law permits the state government to grant sanction for prosecution under Section 153A (inciting communal violence) of the Indian Penal Code.
Turkish officials have privately acknowledged that the matter appeared to be decided. The United States sees the YPG as a valuable partner in the fight against the Islamic State group in northern Syria . Turkey views the Syrian Kurds as terrorists or supporters of terrorists due to their relationship with the Kurdistan Workers' Party (PKK). The US-backed Syrian Democratic Forces has been advancing on the northern city of Raqqa.
Although we'll see more clouds compared to early this week, highs will be very warm topping out in the upper 70s to mid 80s. On Friday , the sun will rise at 6:13:40 a.m. Northwest wind around 6 miles per hour. New precipitation amounts between a quarter and half of an inch possible. Mostly cloudy with a low around 57.
The South Korean politician expected to win a May 9 presidential election, Moon Jae-in, called the test an "exercise in futility". A U.S. official said it was likely to have been a medium-range KN-17 missile, which appeared to have broken up within minutes but did not leave North Korean territory.
The executive director of the Project on Government Oversight, Danielle Brian, said Trump's move - whether or not so intended - "undermines the independence and credibility of that investigation". "The pretext that Comey was sacked because he was too mean to Hillary Clinton sharply contrasts with cries of 'Lock her up.' It is long past time for my Republican colleagues to stop covering up and start exposing Trump to an independent, non-partisan commission as I have urged since November".
Against Everton we lost 4-0 and they had four chances. They made it very hard for us, they played very deep and we didn't create enough chances. And football is scoring goals. "David is one of them". See PA story SOCCER Man City . There was Leroy Sane too, picking his way through challenges with his fast feet. Asking fans last week to judge Pep Guardiola on next season rather than this one, a lot of people will also do the same with the Belgian centre-back, with many believing his best ...
President Trump is to meet with Acting FBI Director Andrew McCabe on Wednesday in the aftermath of his former boss' dismissal. Given that Attorney General Jeff Sessions has recused himself from the Russian Federation investigation, Deputy Attorney General Rod Rosenstein , who wrote a memo laying out the reasoning for Comey's firing, would be responsible for naming that prosecutor.
Candidates who have appeared for the exam can check the results on the official website. Students will need to secure 20 per cent in each written exam and 35 per cent average among all subjects to pass the Gujarat HSC class 12 exams. Students should keep their roll number ready with them before checking the result online. Results may also be uploaded at www.gipl.in (previously www.gipl.net).
Thaçi's PDK eventually supported the rest of the opposition to push for a snap parliamentary vote, before the scheduled date next year. The existing Cabinet will continue to run the country until the election. The Democratic Party of Kosovo of Speaker Kadri Veseli now has the most members in parliament. The vote sets the scene for an early election, about a year before it was due.
Abbas called for a two-state solution based on 1967 borders with the Palestinian capital in East Jerusalem. But in a February news conference with Israeli Prime Minister Benjamin Netanyahu, Trump broke with longtime USA policy by raising the idea of a one-state peace agreement, withholding clear support for an independent Palestine.
At his golf course in Bedminster, N.J., Trump groused over Comey's latest congressional testimony, which he thought was "strange", and grew impatient with what he viewed as his sanctimony, according to White House officials. The investigation has shadowed Trump from the outset of his presidency, though he's denied any ties to Russian Federation or knowledge of campaign coordination with Moscow.
Hours after White House officials disclosed on Wednesday that Trump and his advisers had been considering an executive order to withdraw from Nafta, he said he received telephone calls from Mexican President Enrique Pena Nieto and Canadian Prime Minister Justin Trudeau.
CBS reports that in a press conference today, Balch Springs Police Chief Jonathan Haber said that Oliver was sacked for violating numerous police department policies. Oliver and other officers were responding to a 911 call over "underage kids drunk walking around", and wrongly assumed those were the kids in the vehicle.
Claire Boutet, a 25-year-old French teacher in the city, said that people expected Le Pen to get more votes. Even so, it was a record performance for the National Front, a party whose anti-immigrant policies once made it a pariah, and underlined the scale of the divisions that Macron must now try to heal.
The Trump administration has also been dismayed by Moon's questioning of deployment of a USA missile defense system in South Korea and expects some friction in ties, although US officials say the new president may moderate his stances in office and the effect on the alliance will be limited.
Mr Macron has promised that half of those candidates will be new to elected politics, as he was before his victory on Sunday. Between the first round of the election on April 23 and Sunday's run-off, Ms Le Pen temporarily stood down as leader of her Front National (FN) party in a barely disguised attempt to win the hearts of voters who were put off by its association with racism and xenophobia.
Arkansas State Police officials on the scene are not yet providing any additional details, and say this is an "extremely sensitive situation". Authorities say the suspect was holed up in that home before he surrendered. The deputy was found by a passerby, who notified police. The agency says negotiators are trying to contact the suspected shooter, who is in a home in rural Arkansas.
Russian Orthodox Church spokesman Vladimir Legoyda previously claimed Sokolovsky was not arrested for playing Pokémon Go but instead for making a video provocative to the religious. He said he had already apologised to religious believers, adding that the way he delivered his video was " too cynical for Russian society ". He was detained for several months and faced up to five years in prison.
The decision to move the statues followed a lengthy public process that determined they "failed to appropriately reflect the values of diversity and inclusion that make New Orleans strong today", the city said. flag and the state flag in mourning for the victims - those pictures sparked a contentious debate that led then-Governor Nikki Haley to make a strong appeal to legislators that resulted in the flag being removed from the statehouse grounds altogether.
Tabqa, a strategic town for ISIS in Syria, has been retaken by USA -backed Syrian Kurdish forces, giving allies a new route to the militant stronghold of Raqqa. Ankara has urged Washington to take back the decision, but the Pentagon said the move will not endanger Turkey. FILE - Turkey's President Recep Tayyip Erdogan, gestures as he delivers a speech at a conference in Istanbul, April 29, 2017.
The International Committee of the Red Cross helped negotiate the girls' release along with the Swiss government . Some families support the process, others are angry that more than six months after being released from Boko Haram , they still do not have their children back.
This two-day trip will include a visit to the North and the border region, with the aim of getting a clearer vision of just how Brexit will affect Ireland. He told Irish parliamentarians in Dublin: "Because of its historical and geographical ties with the United Kingdom, because of your shared border and strong economic links, Ireland is in a unique position".


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WASHINGTON — Despite a growing drumbeat to expand the war on terrorism to Iraq, U.S. officials this week suspended key funding to the leading Iraqi group opposing President Saddam Hussein because it has failed to account for tens of millions of dollars in U.S. aid.
The Iraqi National Congress, based in London, was formally notified Thursday that an audit of the group had revealed serious "financial management and internal control weaknesses" in its handling of U.S. funds, according to the State Department. The flaws encompass everything from failure to provide receipts to questionable use of funds.
The concern about the INC's use of U.S. aid underscores the difficulty the Bush administration faces as it debates what to do about Hussein's regime. Washington remains committed to ousting the Iraqi president, but problems with the INC have slowed and complicated the effort.
Besides questions about the use of aid managed by the State Department, the INC has also failed--because of its management problems--to use most of the $97 million allocated to it by Congress under the 1998 Iraqi Liberation Act, U.S. officials say. So far, the INC has used less than $5 million of the money, officials say.


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Cancun - Mexico , Spring break and Adventure
Sorry fo the late post but the last weeks were so busy and changing...
Well finaly I can write and post some awesome pictures from Cancun.
We arrived in Mexico the 30.April. It was a long 5 hour flight with United and when we landed it started raining outside. The first thought was , what really? Rain here but it was warm outside. We changed some Money at the Airport and got us a ride to our Resort.
Our Resort was the Grand Oasis, 20 minutes from the Airport. We gave some tip for the driver and checked in. The Lobby was really amazing, it was like a little rainforest oasis in the middle of the Pyramid- Main Building. Already in the Resort- you totaly saw that it was a Spring break location- a lot of college kids where running around with drinks in their hands.
Our Room was in the more comfortable area of the resort.
Here first impressions:
We spend most of the night with partying. And drinking... But tell me, who would not like to do that in such a great "Entertainment" 5 star resort. I mean, the opinions about it are splittet, but for us college students it was more then enough. A lot of different Restaurants, Poolbars. Entertainment at the Pool and Beach. We met a lot of international people, most of them from England or Canada. Not so many American ones. Most of the colleges Spring Break was over when we came, but still a lot of party there.
(No I will not post Party fotos haha)
On Tuesday we did an awesome Jeep, Dschungle tour. I can really recommend to do a lot of Party but also some culture in between. We have been picked up at the Resort early in the morning and we drove two hours down to Tulum to visit the Maya Ruins. We totaly saw the old Mexican Culture. Walked around got some postcards and walked up to the Maya Park. It was so hot down there in Tulum. We needed a lot of water and energy. The Maya Ruins where unfortunately not as imprassiv as I thought they would be. But still pretty nice. After that one we walked down to the Carrebean beach and then back to the Bus. Next stop would be the Jeep tour through the Dschungle. As soon as we arrived there we got some refreshements and something to eat and then we could pick a Jeep and follow the Guide through the Dschungle. It was an up and down an really a lot of fun! When we arrived at our destination we had to do some different activitys like Kanuying and climbing and finally we could go swimming after that long day! We got a Lunch, prepared by some natives and later we drove back to the resort.


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2634 Timber Dr, Garner
(919) 235-4588
Looking for the perfect place to end your long day? Look no further. TheHibachi Sushi restaurant will welcome you with its friendly service andaromatic Hibachi Sushi kitchen. Located in the heart of Garner,Hibachi Sushi should not be missed.Expand yo...
We were in the mood for japanese food and noticed this place in the shopping plaza. The food wasn't great.. Definitely not going to eat here again.


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Human Polyclonal MAP2K5 Primary Antibody for IF (p), IHC (p) - ABIN754183
Chen, Hou, Ye, Chen, Cui, Tian, Li, Liu: MicroRNA-143 regulates adipogenesis by modulating the MAP2K5-ERK5 signaling. in Scientific reports 2014
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Cameron, Abe, Malik, Che, Yang: Differential role of MEK5alpha and MEK5beta in BMK1/ERK5 activation. in The Journal of biological chemistry 2004
When yeast genetic interaction partners held in common between human OPTN (show OPTN Antibodies) and ANG (show ANG Antibodies) were validated in mammalian cells and zebrafish, MAP2K5 kinase emerged as a potential drug target for amyotrophic lateral sclerosis therapy
For gain and loss of function studies, constitutively active MEK5 (CA-MEK5) and ERK5 (show MAPK7 Antibodies) shRNA lentiviruses were used to activate or knock down extracellular signal-regulated kinase 5 (ERK5 (show MAPK7 Antibodies)). Our results confirmed that low concentrations of H2O2 promoted HUVECs angiogenesis in vitro, and ERK5 (show MAPK7 Antibodies) is an essential mediator of this process. Therefore, ERK5 (show MAPK7 Antibodies) may be a potential therapeutic target for promoting angiogenesis
results confirmed the association of BTBD9 (show BTBD9 Antibodies) and MAP2K5/SKOR1 (show SKOR1 Antibodies) with primary Restless Legs Syndrome in Chinese population
Results revealed the expression of MEK5 was higher in tumor tissues and provide evidence that MEK5 plays an important role in colorectal cancer progression.
Insights into a molecular mechanism by which MEK5 transcriptionally upregulated by Stat3 (show STAT3 Antibodies) augments breast cancer cell EMT (show ITK Antibodies), which subsequently enhances cancer cell invasion and metastasis. This finding may suggest that Stat3 (show STAT3 Antibodies) and MEK5/Erk5 (show MAPK7 Antibodies) pathways could be an effective therapeutic target for inhibition of breast cancer invasion and metastasis.
Our findings confirm an association between the BTBD9 (show BTBD9 Antibodies), MEIS1 (show MEIS1 Antibodies), and MAP2K5/SKOR1 (show SKOR1 Antibodies) SNPs and periodic limb movements of sleep in an elderly cohort.
Specifically, CKS1B (show CKS1B Antibodies) and MAP2K5 significantly inhibited hepatitis C viral RNA replication. PACSIN1 (show PACSIN1 Antibodies), by contrast, inhibited hepatitis C virus infection by decreasing the level of viral protein p7.
High MEK5 expression is associated with colorectal cancer.
SEC16B, MC4R, MAP2K5 and KCTD15 (rs17782313, rs543874, rs2241423 and rs11084753) polymorphisms are associated with the risk for children obesity in China.
Periodic leg movements during sleep are associated with polymorphisms in BTBD9 (show BTBD9 Antibodies), TOX3 (show TOX3 Antibodies)/BC034767, MEIS1 (show MEIS1 Antibodies), MAP2K5/SKOR1 (show SKOR1 Antibodies), and PTPRD (show PTPRD Antibodies)
These results suggest that YAP (show YAP1 Antibodies) promotes muscle differentiation by activating the Abl (show ABL1 Antibodies)/Src (show SRC Antibodies)/MEKK3 (show MAP3K3 Antibodies)/MEK5/ERK5 (show MAPK7 Antibodies) kinase cascade.
MEK5 overexpression inhibits differentiation of osteoblasts.
the MEK5-ERK5 (show MAPK7 Antibodies) MAP kinase (show MAPK1 Antibodies) signaling pathway has a critical role in BAFF (show TNFSF13B Antibodies)-induced mature B cell survival and homeostatic maintenance of B2 cell numbers
The MEK5/ERK5 (show MAPK7 Antibodies) pathway also mediates FSS-induced Runx-2 (show RUNX2 Antibodies) expression in osteoblast differentiation.
finding suggested that REST promoted primordial germ cells survival via regulation of the Mek5 expression
PB1 (show GPR97 Antibodies) domain mediates the association of MEKK2 (show MAP3K2 Antibodies) and MEKK3 (show MAP3K3 Antibodies) with MEK5 and that the respective PB1 (show GPR97 Antibodies) domains of these kinases are critical for regulation of the ERK5 (show MAPK7 Antibodies) pathway.
MEK5 is an activator of ERK5 (show MAPK7 Antibodies) and an essential regulator of cell survival that is required for normal embryonic development
the N terminus of MEK5alpha is critical for the specific organization of the components of the ERK5 (show MAPK7 Antibodies) signaling pathway
MEK5 and big MAP kinase 1 (BMK1 (show MAPK7 Antibodies)) function downstream of MEKK3 (show MAP3K3 Antibodies) in a signaling cascade that induces calcineurin activity through phosphorylation of MCIP1 (show PPP3R1 Antibodies)
A noncanonical function of Map2k5 domain is decribed for coordinated erk5 (show MAPK7 Antibodies) kinase and map2k7 (show MAP2K7 Antibodies) signaling.
The Arabidopsis MKK4 (show MAP2K4 Antibodies)/MKK5-MPK6 (show MAPK6 Antibodies) cascade is an important player in the maternal control of embryogenesis.
results indicated that AIK1-MKK5-MPK6 (show MAPK6 Antibodies) functions in ABA responses and requires ABA-responsive gene expression to regulate ABA-inhibited root growth and cell division. The ABA signaling pathway regulates this MAPK (show MAPK1 Antibodies) cascade.
AIK1-MKK5-MPK6 (show MAPK6 Antibodies) cascade functions in the abscisic acid regulation of primary root growth and stomatal response.
MKK4 (show MAP2K4 Antibodies), MKK5, MKK7 (show MAP2K7 Antibodies), and MKK9, are responsible for the activation of MPK3 (show MAPK3 Antibodies) and MPK6 (show MAPK6 Antibodies) by melatonin, indicating that melatonin-mediated innate immunity is triggered by MAPK (show MAPK1 Antibodies) signaling through MKK4 (show MAP2K4 Antibodies)/5/7/9-MPK3 (show MAPK3 Antibodies)/6 cascades.
Overexpression of MKK5 in wild-type plants enhanced their tolerance to salt treatments. Another kinase, MPK6 (show MAPK6 Antibodies), was also involved in the MKK5-mediated iron superoxide dismutase (FSD) signalling pathway in salt stress.
our data indicate that EDR1 (show PHC1 Antibodies) physically associates with MKK4 (show MAP2K4 Antibodies)/MKK5 and negatively regulates the MAPK (show MAPK1 Antibodies) cascade to fine-tune plant innate immunity.
Data indicate that in the MKK5-RNAi (RNA interference) lines, the induction of CSD1 and CSD2 (show TGFB1 Antibodies) as well as the activation of MKK5 activity were completely arrested.
Results suggest that the YDA-MKK4 (show MAP2K4 Antibodies)/MKK5-MPK3 (show MAPK3 Antibodies)/MPK6 (show MAPK6 Antibodies) cascade functions downstream of the ER receptor in regulating localized cell proliferation, which further shapes the morphology of plant organs.
MKK5 functions both in ozone-induced activation of MPK3 (show MAPK3 Antibodies) and MPK6 (show MAPK6 Antibodies) and in integrating reactive oxygen species homeostasis during ozone stress.
MKK5 is a key regulator of stomatal development and patterning.
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
MAP kinase kinase 5
, MAPK/ERK kinase 5
, dual specificity mitogen-activated protein kinase kinase 5
, mitogen-activated protein kinase kinase 5
, MAP kinase kinase MEK5b
, MAPK/ERK kinese 5
, mitogen activated protein kinase kinase 5


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Sunday, December 14, 2014
The Unfabricated Emotional Calling of Every Christian
Joy, that type of indescribable, strong-willed happiness which doesn't burn out. Joy doesn't falter with circumstances, rest with contingencies or depend on other people. Joy comes from the Creator and Keeper of joy. But the beauty bursts forth when we understand and accept that He doesn't want to hold it for himself. God isn't selfish. He longs to pour it out and over and in us, His created.
This being the third week of Advent, and joy being a touchy subject for me, it only makes sense that I would read and research and listen to what He puts before me.
Hope, I get. Perspective, isn't it? Understanding, isn't it? Great anticipation.
Peace, yes. I know it. I feel it. I can hold it and rest in it.
Love. Don't always acknowledge and feel it like I should, but I am trying to absorb it.
But joy?
That little three-letter word has felt elusive to me. Like a vapor you can't see or touch or ever hold onto.
People don't readily see it in my life. I'm too serious. Too angry too often. Too sensitive about being understood. Too passionate about things that really don't matter. Too judgmental of myself and my life and too quick to disappointment.
And joy? Isn't that something fragile? Something gifted to you that you fumble with but always eventually drop because who can really protect it?
And then I watched this video and Ann, sweet sister, reminds me that joy isn't something you clasp, for it is a flame--a bright powerful light--but it needs oxygen. And we must hold our hands open and not clasp them in anger.
Anger, the antithesis of joy. But she says the antithesis of joy is disbelief, a cynicism, a snide, sarcastic and pessimistic response. And my heart aches because I keep hearing that idea. And I'm pricked. I fall into that trench.
Is my heart shadowed by anger, God? I already know the answer and yet I am incapable of cleaning house myself. I don't possess the agent abrasive enough to scour the scum. Immediately, my fix-it mode vamps up and says, "we can figure this out though." But I can't; I know I'm incapable.
Joy comes from the Father, but we help cultivate it when we worship. And worship comes from a secure place of peace, understanding my place with Him and knowing His deep love. That deep love and security floods over the muck of anger, washing it away.
So really, we can't isolate the blessings of Advent.
They are the intertwined fingers of grace. This peace comes from hope that comes from love that gives us excessive joy. OH, how I long for that!
When my joy feels squelched, I ask him to unclench my hands and help me back to the place of purity. What do I think I need? What do I really need? My hands start to feel the rough tree of the cross and am I getting it little by little. Again, I need to hear it.
I love you, do you understand? I love you. Do you see?
And nerves set in and I feel jittery and cold and helpless, shivering here on this couch. Will I ever get it, Lord? Why is my skin so thick and unwilling to absorb this? Why can't I just soak in your love and warmth? I don't deserve it. So I say. So you say too, but you give it anyway. And I've received. I've opened. But have I taken this gift out of the box. Do I wear it as a garment? I am naked and cold without it. I am bare when I refuse to accept that which I don't deserve but desperately need. I am so dependent on His love. So utterly dependent.
Lord, hear this desperate cry. I want to hold onto you. Help me to understand that clinging to you means letting go of all else and unclasping my hands and reaching upward with not only Hope for the future, but Joy in this moment because your Love is more than sufficient for me then, for me now. In this moment. When I am weak.
And Peace, Joy, Hope, Love--this beautiful braid of His grace come down to us, living within us, helping us step forward on this foreign soil till we make it Home.
Labels: Advent, anger, emotions, Hope, joy, letting God, Love, Peace, understanding
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Sofia Vergara and Fernando Fiore Reunite
Sofia Vergara and Fernando Fiore reunited a few days ago and we're sure they had plenty to talk about.
The two of them shared hosting duties on Univision's Fuera De Serie.
Its been years since they've done that, we included a pic from way back when, so it was neat to see them together again.
Related posts:
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text: I was thinking about shooting something using my mini-DV camera and figured I may simply need to get another tape recorder like the NAGRA to record the audio track. But waitaminute, I have an iPod! And waitaminute! I have a BELKIN adapter which will enable me to use it to record audio. Is anyone else doing this? I think the sound recording is great. I'm thinking about getting the BELKIN adapter for external microphones to connect the ipod to a shotgun microphone. It seems like a logical way to get around buying a NAGRA or DAT recorder. Thx


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The festival of lights Deepawali or Diwali is the most important festival of Hindus in India. On the day of Diwali festival people clean up their houses put bandhanwar or door hangings and make Rangoli, , at their entrance and perform puja in the evening. People buy special food items, sweets and fruits to be offered to Goddess Lakshmi, God Ganesh and God Kuber during worship in the evening. Goddess Lakshmi and God Kuber are worshipped together to increase the benefits . Aartis (devotional hymns) are sung to praise of the Gods to get their blessings. After the lakshmi puja, earthen lamps are lit, Prasad is eaten. children light fire crackers. Sharing is an important aspect of the Diwali festival. People put on new clothes and visit homes of their friends and relatives to share delectable sweets and dry fruits, burst crackers and exchange gifts. A host of gifts are available on thegiftipedia.com, such as lakshmi and ganesha idols, cookies, chocolates, bamboo fruit basket, bamboo chocolates basket, bamboo flower pot, decorative candle, sweets, dry fruits, jewellery and more.


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Coming of age - real life
That thread made me think: when did this happen to me - the move from childhood into adolescence?
The films and books like it to be a single, life-changing event but it probably happens gradually. I can pinpoint mine to around this time of year in 1982. I had fallen in love with Carmen Turner and it took me about 6 months to pluck up the courage to ask her out. She came round to mine on a Saturday night when I was babysitting and we watched The Omen on VHS and drank shandy.
1994 motherfucks
First kiss, first booze up, first girlfriend, first whatever.
But what I did come here to say was that all these "coming of age" programmes, like Skins and now House Party and all that BBC Three / E4 stuff is always good looking young kids who happily shag eachother and go to pool parties and are confident and buffed.
If this was what it was actually like at 16 then I missed all of that. I was skinny, small, gawky, scared all the time, hated myself and my body and the idea of gonig to a pool party made me want to cry.
Fucking confident pricks.
still waiting
how do you tell?
i dunno
DD this's one of your posts?
- Si_Badvibes this'd this
It seems so easy in the films
but in something like Stand By Me, they probably just remember being weedy kids who went to find a dead body, had a couple of scrapes on the way, found the body, then went back to being weedy kids tormented by bigger boys until they got to about the age of 17.
If we're saying coming of age is when
you found a dead body in the woods, then I came of age about 12 times in the 90s.
mine was definitely the whole summer holidays at the end of year 9
first summer of getting drunk, first proper boyfriend, I remember it being really hot and sitting outside in fields in the day, then staying up really late at night and watching MTV2. Seems pretty idyllic now even though I'm sure it wasn't all like that. It was also the year before I got a summer job as well so it seems like I had nothing else to do.
14 seems very young to me now, but at the time I felt like I was WAY behind all of the cool people at school in doing all of this stuff.
Mtv 2
Oh I loved that channel.
me too!
I remember it showing videos for Metallica's Until It Sleeps and Bone Thugs N Harmony's Tha Crossroads all the time.
my friend's picked videos for the viewer's choose thing
it was shown about 3 in the morning. Mine was never shown, was probably 100% idlewild or something.
120 Minutes!
I used to spend ages picking my choices, never sent them in though.japes this'd this
used to love 120 minutescolossalhorse, incandenza_, and Smyth2 this'd this
I remember Royksopp Remind Me being on quite a bit
Sometimes got lucky with Aphex Twin
Doing homework in front of 120 minutes!!
It tends to be summer doesn't it?
spent three consecutive summers in a seaside town in Corinth in the mid-90's. They were family holidays but we were basically left to our own devices. Hung out with same group of friends and think we all went through a lot of firsts together. Had a ridiculously unrequited crush on a girl called Evina. Tanlines and freckles. I look back on those sunkissed days with a certain soft focus nostalgia. Days consisted of hitting the beach, playing pick up basketball and long lazy lunches. The evenings of bonfires, outdoor cinemas and underage drinking.
Maybe it was a school trip abroad
age 13. Some of us got served for booze (didn't really get pissed though), got served for cigarettes and smoked quite a bit, got off with a local girl on the beach, got left to our own devices in water parks and on trips to various places around Italy.
Summer of 2000
The year before Id spent drinking and doing drugs, but that summer I read the silmarillion and LotR by a lake drinking tea from a flask while listening to eels and weezer. Stifling a tear as i write this tbh
I had started at a new school aged 13
it was everyone's first day (public school innit). Sept 89. The cool kid (John Adams) had us all lined up and asked us one by one what bands we liked. The Cure or PWEI would have been examples of cool answers. I liked U2. I wasn't there, but it seemed I had potential and was invited to hang out with him in Guildford.
He met me at the station that Saturday. I hadn't bought a ticket at the start of the journey. I wanted to go buy one but he knew a way you could sneak out without paying.
I spent the evening with people who drank and smoke. I didn't partake in either of those activities that night but it was too late. I had seen the dark side. And thus followed years of academic under-achievement, hedonism, and a kinship with subculture which still forms part of my identity 25 years later.
Don't know what happened to John. I hope he wasn't one of the seemingly numerous casualties from era (suicides, breakdowns). Would love to meet him now and explain the effect he had as I don't regret the way things turned out. Would have achieved more I guess, but I love my life. Don't believe in fate but I was definitely presented with a t-junction that day in the dayroom and am perfectly happy I was convinced to turn left.
guildford is still like that
where was the seedy underbelly of guildford in 1989, the river?
Meet at the Arches (pillars half down the high st on the left), then either to the river or the castle ground.
Probably was the summer after my GCSEs
I was never a big drinker at that age, but it was more about a number of factors:
- getting a new bunch of friends away from school;
- starting to learn to play guitar (I used to play the flute in school. Yes);
- getting into bands for the first time (though this probably started a year or two earlier);
- getting an ounce of confidence.
she paid Noah to do a private dance while watching the omen, changed her name to Tina and the rest? The rest is history.
Mr BadVibes is pretty close
After popping my cherry, she ditched me and took up with a lad in the year above us (he wasn't called Ike btw). They got married 10 years later (I shit you not) and had 3 kids
The school bully Ike?
he was a bad lad.
oh right. Not called Ike. Only just woken up
i reckon the year of 2007`
went to leeds fest so it was the first proper taste of independence. being with girls properly, doin adult stuff (even just drinking). fun times
for me it was 10th june 1998 - aged 12, watching Scotland get beat at football
by a better team on the world stage whilst off my tits on my first cans of Tennents. later on, i spewed, tried to kiss a family friend, and then witnessed a 8 year old girl have her head split right open after she walked into the swing of a gold club. i don't think i was the same kid again after that day.


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Columbia is a former California Gold Rush boom town that lives on as a state-preserved historic park and a National Historic Landmark that preserves the original, gold-rush-town flavor of the town, once dubbed the "Gem of the Southern Mines." Founded in 1850 by Mexican gold miners, it is in Tuolumne County, California, United States. Although only about 2,000 people now live in this region near Sonora, California, at its height it was California's second-largest city. It was even considered briefly as a site for the state capitol of California. In 1854 the bulk of the town burned down and was re-built with brick and iron structures that survive to this day. Columbia's main street, part of the Columbia State Historic Park, is closed to automobile traffic but is open to horses and carriages, as well as pedestrians.
The town, now technically a census-designated place (CDP), is located along State Route 49 just north of Sonora. The US Postal Service ZIP code for the community is 95310. Wired telephones in Columbia work out of the Sonora central office.
Major points of interest in the area include Columbia Community College, a two-year, community college. Columbia Airport (FAA designator: O22) includes one 4,670-foot (1,420 m) runway and is busy with firefighting aircraft during summer. The annual Columbia Fire Muster here is often the earliest of California's summer musters.
Within weeks of the discovery of gold in the vicinity of Columbia, thousands of miners arrived and the population climbed to 5,000. By 1852, there were 8 hotels, 4 banks, 17 general stores, 2 firehouses, 2 bookstores, 1 newspaper, 3 churches, and over 40 drinking/gambling establishments. In 1854, Columbia's first fire destroyed 6 city blocks. The town was rebuilt using brick and iron materials. In 1857, another fire burned down nearly everything else, except the brick buildings.
In 1851, the local community brass band, a popular institution, greeted the arrival of the first white woman in town.
The Columbia school house was built in 1860, renovated in 1872, and finally closed in 1937. In 1947, it was purchased by the state of California for $1 and incorporated into the state-historic park.
By 1860, the gold mined in Columbia was diminishing rapidly. The only land left to mine was in the city itself. Miners dug under buildings and tore down houses to get at the gold beneath the city. The nearby town of Copperopolis had discovered copper and was experiencing a boom. The bricks from the destroyed buildings of Columbia were sold to Copperopolis for construction purposes.
Between 1850 and the early 1900s, $150 million in gold was removed from the surrounding hills.
Columbia never became a ghost town. In 1945, California created Columbia State Historic Park from the remains of the historical buildings of the city.
Rev. John Steele wrote his accounts of the Indians of Columbia in his memoirs In Camp and Cabin during his time in the gold rush era. The Indians of the village of Columbia were Mi-wuk.
Columbia is located at 38°2′2″N 120°24′4″W / 38.03389°N 120.40111°W / 38.03389; -120.40111 (38.033881, -120.401172) at an altitude of about 2,100 feet (650 m).
According to the United States Census Bureau, the CDP has a total area of 6.2 square miles (16.0 km²). Only 0.16% of the total area is covered by water.
As of the census of 2000, there were 2,405 people, 1,063 households, and 659 families residing in the CDP. The population density was 389.7 people per square mile (150.5/km²). There were 1,162 housing units at an average density of 188.3/sq mi (72.7/km²). The racial makeup of the CDP was 90.10% White, 0.87% African American, 1.41% Native American, 1.29% Asian, 0.12% Pacific Islander, 1.29% from other races, and 4.91% from two or more races. Hispanic or Latino of any race were 6.90% of the population.
There were 1,063 households out of which 22.6% had children under the age of 18 living with them, 44.3% were married couples living together, 13.0% had a female householder with no husband present, and 38.0% were non-families. 29.7% of all households were made up of individuals and 14.3% had someone living alone who was 65 years of age or older. The average household size was 2.18 and the average family size was 2.65.
In the CDP the population was spread out with 20.2% under the age of 18, 10.0% from 18 to 24, 18.8% from 25 to 44, 28.1% from 45 to 64, and 22.9% who were 65 years of age or older. The median age was 46 years. For every 100 females there were 89.1 males. For every 100 females age 18 and over, there were 88.4 males.
The median income for a household in the CDP was $29,173, and the median income for a family was $35,000. Males had a median income of $40,729 versus $23,750 for females. The per capita income for the CDP was $18,731. About 20.2% of families and 19.0% of the population were below the poverty line, including 37.7% of those under age 18 and 1.4% of those age 65 or over.


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When it comes to financial services, we've talked about online behaviors for the end user and for the brand itself. But how are individual finance professionals using online and social platforms? This survey from American Century Investments takes a closer look.
The most popular social tool for business use is far and away LinkedIn. Thirty three percent of financial professionals are using that tool, while relatively few are using Twitter, Facebook or blogs.
In terms of how they use social tools, the most popular function is to collect information, more specifically to read expert commentary and insights. Finance pros also use social tools to research people and share content that might be relevant to clients.
Given the finance professional's preferred tools and purpose for social media use, we've identified a few strategies to make that experience better. Add these habits to your daily routine to find a stream of high quality insights and discussion opportunities on LinkedIn.
1. Follow LinkedIn Today Channels
LinkedIn Today is the network's social news page, and is a great way to discover the latest finance insights from a variety of sources. To get started, follow topic areas that interest you and your clients. The content will appear on your homepage stream and, if you set it that way, can even be delivered to your inbox via an email digest. Here are a few channels that overlap with financial services:
- Economy
- Entrepreneurship & Small Business
- Leadership & Management
2. Follow Thought Leaders
You can also find content by following trusted industry Influencers. LinkedIn curates a list of influencers in various industries who create their own content as well as share insights from other sources. Influencers can also serve as a great guide for the kind of content that you and your company should share online. Here are a few financial services influencers to check out:
- Jim Kim, President at the World Bank
- Sallie Krawcheck, Past President of Merill Lynch, US Trust and Smith Barney
- David H. Stevens, President and CEO at Mortgage Bankers Association
- Michael Moritz, Chairman, Sequoia Capital
- Linda Descano, Managing Director at Citi
3. Join LinkedIn Groups
LinkedIn Groups are notoriously spammy, but if you find the right one, it can be a great place to find, share and discuss industry insights. Below are a few of the larger groups finance-focused groups. If you prefer a more curated experience, ask members of your network which groups they recommend.