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Thank you Ranger Boats
llyon Posts: 5 Greenhorn
in Ranger Boats #1
Last Friday June 24, 2011 I launched my 2005 223 Cayman with my twelve year old and his friend for an evening of fishing the Ortega River bridge in Jacksonville. We emptied our crab trap for bait where the St. Johns was oil glass calm. By the time we launched and headed south under the Fuller Warren bridged (I-95) , we noted that the river was white capping under a fast moving evening storm. We thought we could make it to the Ortega river where it is somewhat protected as planned when it started lightning about half mile ahead of us. So, we turned around and headed back to the boat launch at River City Brewery under the Acosta bridge for those who are familiar with the area and got in some serious trouble. We were running against a fast moving current with a trailing sea due to the wind I would estimate at around 20 to 30 knots. To complicate matters further, there is a concrete seawall which made the conditions extremely unorganized. My first thought was to stay on the power with the engine trimmed up to help the bow reach the top of the back of the waves in front of us. The risk was that I would bury the bow at a higher rate of speed than I thought we would be able to survive. I then backed off the throttle and tried to ride the back of the waves kind of sitting in the trough when we were pushed from behind by a trailing wave and buried the bow into the back of the wave in front of us which is what I was trying at all costs to avoid. In what seemed like slow motion, we completely filled the cockpit with water as I was hammering my Mercury 250 Optimax into reverse. As soon as my bow surface again, I then hammered the Optimax full throttle in hopes of saving the boat. The bow was sticking straight up in the air, waves were coming over the stern, the Optimax was about 50% submerged and it seemed we were hanging in suspended animation. The boys were bailing, the bilge pump was shooting a three foot stream of water and the self bailing cockpit was working overtime getting rid water. I honestly thought I had lost the boat. However, after about a minute, I began to notice improvement as the Optimax continued to groan and the water level began to drop I knew as long as the Optimax would hang in there we had chance. Finally, all the water was out of the boat the engine sounded familiar again and we negotiated about another hairy mile in order to get back to the ramp. I have to thank an anonymous boater who was ahead of us for keeping an eye on us loitering just under the Acosta Bridge until we make it safely. It was comforting knowing at least someone was aware of what was happening to us in the event the very worst came to pass. To who ever you are on behalf of myself and my crew I say thank you. The next day fishing the intercoastal, my son and I along with the father of the boy who was with us the day before commented on all the boats we encountered as not able to survive our harrowing experience. I am thankful I bought a Ranger and I am thankful I have a 250 HP Optimax without which I don't think we would have survived our friday evening of fishing. Buy quality boats and do not under power them.
Tanks Ranger (pun intended)
Tanks Ranger (pun intended)
Ranger Boats HQ Posts: 15 GreenhornGlad to hear you guys are alright!0
Renagade69 Posts: 1,228 Officerwow. Nice story.Hells Bay Estero Bay Boat and Hells Bay Marquesas0


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I took a package of Taiwanese Tie Guan Yin that was not so great to begin with, and had been forgotten in the back of the cabinet. It was not bad, but had definitely lost whatever edge it had. I put it in a flattish bowl in a small convection oven set to 275 degrees, and roasted for a total of just over 20 minutes. During a good part of that time the oven was still heating up, but by the end of it the leaves were turning brown, and their temperature was above 200 degrees per the infrared thermometer (forgot to note the exact temp).Whatsina... wrote:i was also unaware that reroasting a green gaoshan was a useful technique. home roasting sounds like a fun adventure regardless of the outcome.
here's hoping the end result is delicious. good luck and let us know what you do and how it goes!
The first infusion is not as fine as the unknown Dong Ding I enjoyed last week, but still, quite tasty, and an improvement over the undistinguished prior incarnation.

subset: commoncrawl


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Berdych Downs Federer To Reach Dubai Final
Third seed Tomas Berdych saved three match points before beating defending champion Roger Federer in the semi-finals of the Dubai championships on Friday to set up a final against Novak Djokovic.
Czech Berdych recorded his fifth win in eight matches over Federer, triumphing 3-6 7-6 6-4 while top seed Djokovic extended his winning streak to 17 matches by beating Juan Martin del Potro 6-3 7-6.
Djokovic and Federer have claimed eight of the past 10 Dubai titles between them and the 5,000 capacity crowd were urging the world's top two to win through under the floodlights.
Serb Djokovic obliged in the first semi but a tired Federer fell short, losing at the semi-finals stage of the tournament for the first time in eight appearances.
"I couldn't have a better feeling than this one, coming from court playing Roger almost in front of his home crowd," Berdych told reporters.
The Swiss went into the match with an 11-5 winning record against the world number six, although the Czech had been victorious in four of their past seven meetings, including at Wimbledon and the U.S. Open.
Federer broke in the first set when Berdych slugged a whipped forehand from mid-court into the net for a 5-3 lead. He sealed the set with a second set ace.
The Swiss surged from 5-2 down in the second, but then fluffed three match points in the tiebreak before Berdych forced a deciding set with a bludgeoned return winner.
In the final set, two miscued forehands and a double fault from Federer gave Berdych two break points at 2-2.
The Swiss saved the first with an ace, but skewed another forehand wide to fall 3-2 behind and Berdych served out the match.
"I leave this match with a lot of regrets," Federer told reporters. "The match was in my racket. You do all the right things for so long and then at the end you've got to explain why you didn't hit two shots decent."
Earlier, Djokovic came from 3-0 down in the second set against Del Potro to serve for the match at 5-4.
But he faltered as Del Potro - the only man outside of the men's 'big four' to win a grand slam tournament since 2005 - forced a tiebreak as his fellow Argentines in the stands raucously chanted his name.
Djokovic ultimately triumphed, a forehand winner from mid-court the only point in the tiebreak going against serve.
"His serve is very powerful, his forehand from the back of the court he can do anything with - I needed to stay in it when I was a break down," Djokovic said in a courtside interview.
The 25-year-old boasts a 12-1 winning record against Berdych and will expect to claim a fourth Dubai title in five years on Saturday, although the Czech, who seems stronger and more agile this season, could yet spring another surprise.
"I will have my homework for tonight to try to find out something that could work at least a little bit," said Berdych.
"He's one of the best moving players I've ever seen, especially on the hard court. This makes him very, very tough to play. I will try to be patient. Wait for my chances. The court is very fast, so it could help my strokes."


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Actor Pierce Brosnan has sold his Malibu beach retreat for $2.6 million.
Brosnan and his wife, environmental activist and former broadcast journalist Keely Shaye Smith, put the property on the market at $3.9 million in 2010 while building another house nearby.
The gated Mediterranean they sold has separate space for use as an office or media room and sits on more than a quarter of an acre with lawn space and a courtyard fountain. The flower boxes and hydrangea-lined pathways are perhaps a nod to Brosnan's Irish roots.
Features include arched windows and doorways, high wood-beam ceilings in the living room, walls of glass, plank oak...


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The Crummey trust: Keeping both the IRS and the creditors at bay is taking some fancy footwork
The Crummey trust: Keeping both the IRS and the creditors at bay is taking some fancy footwork
Author Charles Rounds explores recent developments regarding Crummey powers and proper actions for trustees.
Since Crummey v. Commissioner was decided in 1968, the IRS has been making life difficult for the settlors of Crummey trusts. Only recently the parties again skirmished, this time over whether an in terrorem clause in the governing trust instrument per se renders withdrawal rights illusory. See Mikel v. Commissioner, T.C. Memo, 2015-64. It does not. Chalk up another victory for the taxpayer. While the Crummey trust continues to be an effective tax avoidance vehicle, the very feature that makes it effective potentially exposes the underlying property to the reach of the creditors of the holders of the withdrawal rights, namely the withdrawal rights themselves. In California and New York most notably the risk appears to be a serious one. Charles E. Rounds, Jr. discusses the Crummey trust generally, and these specific tax-avoidance and creditor-access issues in particular, in §9.18 of Loring and Rounds: A Trustee's Handbook. The entire section, with some post-publication enhancements, is reproduced in its entirety here.


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Bardot is the ultimate outfitter – our top of the moment seasonal trends and style classics are a trusted friend to girls seeking the ultimate look. Bardot is an exciting 'dressing room' that surprises each time you enter.
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Nokia Reportedly Looking To Start Its Own MVNO In Japan
from the so-many-people-think-nokia-is-japanese-anyway... dept
A local report says that Nokia is considering setting up an MVNO in Japan, focused on its high-end Vertu line of handsets. Nokia has a small presence in Japan, making it one place -- along with the US -- where its market share lags badly behind its 40 percent or so global share. It would be surprising to see Nokia make a big move into becoming a virtual operator in any market, given that it sells most of its handsets through operators, and wouldn't want to jeopardize those relationships in any way. However, for its Vertu line, it could be a useful model. Vertu devices aren't your typical mobile phone: they cost upwards of several thousand dollars, and often don't include features common on much cheaper devices. They eschew many technical features in favor of expensive build materials and a concierge service for its deep-pocketed customers. Vertu handsets aren't going to be sold by or subsidized by operators, so Nokia could benefit by bundling service with the device as a virtual operator, making the Vertu brand the only one that has any contact with the customer. Given the small number of devices it sells, operators aren't likely to mind too much. But if Nokia made a bigger grab for the mass market, they'd certainly take exception.


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Sorry, but specific product you requested is not currently available. Hopefully you can find another option below.
70% Undyed Baby Alpaca / 30% Undyed Merino Wool. Soft and wearable, this eco-duo comes in natural marled colors. This hand washable yarn is a nice option in natural, un-dyed colors. The colors are just as they come from the sheep with 197 yards per skein.
Cascade Eco Highland Duo Yarn and Cascade Highland Duo Yarn are both similar yarns: alpaca, hand wash, 4.5 sts / inch, 100 gram, on size 8 US needles, 197 yards.
What about yarn that have the same look and feel? Find more yarn that is undyed, a smooth / uniform texture, and is undyed.
You may enjoy taking a look at the Cascade Eco Duo Barclay Sweater, Cascade Eco Duo Gorgeous Gathers Cowl, and Cascade Eco Duo Braided Beauty Cowl kits all using Cascade Eco Duo Yarn.
Hopefully our suggested project ideas for Cascade Eco Duo Yarn can help you come up with your next exciting new project idea!
We provide endless possibilities for you including yarn, knitting gifts, needles, kits, sale yarn, free knitting patterns, and more!Jimmy Beans Wool is Your Local Yarn Store... Online!


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FHA Loan Eligibility Requirements for Your City, Your State
Since 1934 The FHA has helped over 34 million people become homeowners. Its mortgage insurance program allows lenders to ease their eligibility requirements, making homeownership accessible for people in neighborhoods across the country, including Your City, Your State.
With FHA's insurance, lenders know they'll be paid back if a borrower defaults. That reduces their risk and enables them to lend more liberally.
This guide will answer some of your questions about your eligibility for an FHA purchase loan. And if you're already a homeowner, you'll learn about refinancing through the FHA Streamline Refinance Program.
Eligibility Overview for FHA Loans in Your City, Your State
To be eligible for an FHA loans in Your City, Your State, you must intend to occupy the home. So, rentals or second homes generally don't qualify. The home must be a 1 to 4 unit property (you may be able to get a loan for a multi-unit property if you intend to live in one of them).
Beyond basic eligibility you'll need to meet some minimum qualifications:
- You must have a down payment of at least 3.5 percent.
- You must qualify for financing on the balance of the purchase price.
- You must be able to sustain the monthly payments�including the FHA mortgage insurance premium.
- You must have a steady employment history or have worked for the same employer for at least two years.
- You must have established a clean credit history over the previous two years.
- The property must be appraised by an FHA-approved appraiser and meet certain standards.
About Those Occupancy Requirements
As we've noted, your FHA-insured loan must be for your primary residence. That means you intend to reside there for the majority of the calendar year. And you must move in within 60 days of closing.
Property Types
Many property types are eligible for FHA mortgage loans:
- Single-family homes
- Townhomes
- Multi-unit properties (up to four units)
- Condominiums
- Manufactured homes
A single-family home is a standalone property or one that shares one common wall with another building. If it is attached to another building, there must not be any access from that building to your home.
A townhome is a one that is attached to other units in a row. Each unit shares a roof and a common wall with the adjacent units. Each of these units is intended to house a family. These properties meet basic FHA eligibility requirements.
A condominiums is one unit of a multi-unit complex. The owner owns the inner walls and space within the home and shares ownership of the outside property and grounds with the other owners. A condo owner usually pays homeowners' association dues in addition to a monthly mortgage payment. These dues pay for maintenance and repair of common areas such as pools, gyms, green strips, and clubhouses.
Important note: For a condo to qualify for an FHA loan the entire condominium community must meet FHA eligibility requirements.
A manufactured home is built in a factory and then shipped to the property site. It is then placed on a permanent foundation. At that point it is regarded as an immobile property and can be FHA insured.
Some additional requirements for manufactured homes: They must be at least 400 square feet, meet strict safety guidelines, and have been constructed after June 15, 1976. The foundation and elevation of the land underneath must also meet FHA eligibility requirements. And the borrower must own the land underneath the home for it to be FHA insured.
The FHA 203k loan program allows funds for rehab work on a property. This is a popular option for buyers who want to add their own upgrades after their purchase. It works especially well for single-family homes that require minor cosmetic upgrades such as carpet, kitchens and paint.
Your Credit History
An FHA loan doesn't require perfect credit. Most conventional mortgage lenders look for credit scores above 700. You may qualify for an FHA mortgage with only a 620 score. FHA allows up to two thirty-day late entries on your credit report.
FHA also makes allowances for those who don't have any credit history. In these cases, recent utility bills and proof of payment are acceptable substitutes.
Foreclosures, bankruptcies and short sales won't necessarily disqualify you from an FHA loan. In some cases borrowers can qualify in just a year after a short sale, bankruptcy, or short sale.
You must show that you experienced a financial hardship caused by �extenuating circumstances,� leading to loss of income and/or employment. And you must demonstrate that you've achieved financial stability since then.
Income Requirements
FHA mortgage lenders in Your City, Your State will want to see evidence of at least two years of continuing employment with steady or increasing income and very few gaps of unemployment.
FHA typically allows a debt-to-income ratio up to 30 percent. (This is the percentage of your gross monthly income that you pay for your mortgage.) This is more lenient than most conventional loans, which only a 28% ratio.
For example, on a monthly income of $4,500, an FHA loan might allow a monthly mortgage payment up to $1,350. A conventional loan might only allow a maximum payment of $1,260.
Required Documents
If you meet all the eligibility requirements for an FHA loan in Your City, Your State and are ready to begin the application process, you can start gathering your preliminary documents.
Here's a checklist:
- Evidence of residence for the past two years
- Social Security card
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- Information on all active loans
- Information on any other owned real estate
- Approximate value of all personal property
- Past two years of W-2 forms
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- Past two years of personal tax returns
Down Payments
FHA requires a down payment of at least 3.5 percent. This is far less than conventional mortgages, which may require 5 percent, 10 percent or even 20 percent down.
On a $300,000 home, your down payment with an FHA mortgage could be as low as $10,500. With a conventional loan it might be $15,000, $30,000, or even $60,000.
Those large down payments make conventional loans unattainable for many would-be buyers. And that makes the FHA option more attractive.
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In Paris they have different and higher standards of urbanity. This is referred to as a suburb:
In Paris they have different and higher standards of urbanity. This is referred to as a suburb:
Pretty, but not unprecidented on this continent.
Chicago calls this a suburb:
Is it an inner-ring suburb, though? Remember, the hypermarket was invented in France, and a Carrefour store (and the accompanying bad architecture and expanses of pavement) makes a US southern exurban Wal-Mart look like a quaint small village shop in comparison.Originally posted by ablarc
As jordanb said, there's many urban suburbs in the US; around Chicago, New York and LA; Cleveland Heights and Lakewood, Ohio; Miami Beach, Florida, and University City, Missouri to name a few.
Growth for growth's sake is the ideology of the cancer cell. -- Edward Abbey
However ugly the hypermarkets may be, they're usually confined to industrial areas, rather than replacing such urban cityscapes as Ablarc has presented. In those Southern exurbs, however, Wal-Mart and his buddies have all but ruled out any sort of urbanity.
After googling around, I found this interesting article from the BBC. (I'm quoting the entire article, because I don't think BBC articles are copyrighted works; please correct me if I'm wrong.)
Urban sprawl is not unknown in France. Champigny, outside of Paris, resembles a budding American suburb, with a Gallic flavor.
Thursday, 19 July, 2001, 11:27 GMT 12:27 UK
French suburbs under siege
France's suburbs are plagued by crime and violence
By Andrew North in Paris
"Suburbs - a hot summer?" asked the front page headline on a recent edition of the daily Le Parisien.
This was not idle speculation as to how affluent suburban residents would cope with the sweltering heat of July and August.
In France the suburbs, or banlieue, are the equivalent of America and Britain's inner cities - home to the poorest members of society, with high concentrations of immigrant groups - and plagued by crime and violence, much of it committed by young people.
The number of these problem suburbs has doubled to 1,200 in the past 10 years and increasingly the authorities seem at a loss as to how to deal with them.
It was the bleak and often violent 1996 film, La Haine, that brought conditions in the banlieue to wider attention.
Set in a rundown Parisian suburb, the poor residents * white French and people of North and West African origin * have become alienated from society at large and see the state not as a source of help, but only as a threat.
This sense of alienation is at the root of the problem in real life, according to Professor Alain Bauer, an expert on policing and urban violence at Sorbonne university.
So much so that when violence flares between the authorities and banlieue residents, other divisions - including race - are forgotten.
"Even when we have two gangs that fight each other, when the police come, they re-unify against the police," Professor Bauer says.
Problem Trappes
One of these problem suburbs is Trappes, a town of about 30,000 people to the west of Paris, of whom about two-thirds are of immigrant origin.
A short distance away is the palace of Versailles and it is surrounded by affluent, mainly white areas.
But the decline of the nearby industrial zone that brought immigrant workers to Trappes in the 1960s and 1970s has left an area of severe deprivation and one which now has the worst record of violence in the western Paris region.
Almost every night, cars are set alight in the streets between the crumbling apartment blocks in which most people live.
Police on patrol come under frequent attack.
"They throw stones and bottles all the time," said Christian Meyer, chief of police in Trappes. He says his police station has also been fire-bombed on several occasions.
Mr Meyer says youths of Moroccan and Algerian origin are largely responsible. He says they sometimes try to compare themselves to the Palestinians fighting the Israelis.
In some suburbs, rates of youth crime have risen by 40% in the past two years.
Child curfew
The police are often powerless, admits Philippe Thevenard, deputy chief of police for the Yvelines district, which includes Trappes.
"If they are under 13 years old, and many are, there's nothing we can do under French law," he says.
Recently, the town of Orleans in central France decided to adopt its own solution and introduced an 11pm curfew for children of 13 and under. Several other cities have followed suit.
Mr Thevenard says a curfew would help in Trappes, and several local residents told the BBC they agreed. Some had young children who had been involved in violence.
However, they said addressing the causes of the town's deprivation should be a higher priority.
Mohammed, a Moroccan-born father of two boys, said he wanted to see more investment in education and training to give young people a better chance of finding jobs.
He said the authorities also needed to do more to tackle what he says is racial discrimination against Arabs, which prevents them from getting the jobs they need.
Here's Saint-Parres-les-Vaudes.
Le sprawl.
France's suburbs are, on a whole, probably more urban than suburbs in North America, Australia, New Zealand and South Africa; land is scarce, and many European countries regulate "out of town development" on a national scale. When a Paris suburb is done right, the effects are probably spectacular, as ablarc showed us. Still, they're not without their problems.
The density of Paris suburbs have deeper cultural roots. In the 1800s, the Fench and English concept of what was considered an ideal living environment were much different. The French preferred four and five story apartment buildings; the English aspired to a leafy building lot far from the city, where you could maintain a garden and breathe fresh country air. The early 20th century - France gave the world Le Courbesier, the UK greenbelt and garden cities. The cultural roots of the US are closely tied to the UK, so there's little wonder the English ideal prevailed here, especially considering that the US has the land to pull it off.
Growth for growth's sake is the ideology of the cancer cell. -- Edward Abbey
The problem I see is: How do you "address the underlying causes"? The Algerian, North African, and poor white native French are basically trapped. They lack postmodern skills (if there was even really enough demand for such skills to employ everyone, which I seriously doubt) but they cannot/are not allowed to/will not work at the levels of absolute deprivation established by the desparate, yet increasingly skilled ex-peasants of the dominant new economy, China, and its satellites.
We have the same problem here, of course. Can every ex-steelworkers son in Hegewisch really expect to be a graphic artist or computer programmer (especially as such profeszsions can be accomplished far more chealpy overseas). I don't care how good your community college systems are.
Is this Evanston, jordan?Originally posted by jordanb
No, only the parklike cemetery (Calvary Cemetery) in the foreground is in Evanston, the buildings are actually the Rogers Park neighborhood of the City of Chicago. The major street is Sheridan Rd, the street between that and the lake is Eastlake Terrace and the street closest parallel to the cemetery is Juneway Terrace.Originally posted by BKM
OTOH, much of Evanston is about that dense.
Comparing Europe and the US's development patterns is not always a good idea. The bulk of Europe was developed before the proliferation of vehicular traffic. Sure there may be places where a comparsion is warranted due to density concerns, but to simply assume that we can do something because it's done in Europe is a falsehood.
That's not all true. In the Netherlands, the majority of the housing stock was developed after WWII, so the vehicular traffic was not the reason for this high density. Only the historical centres are not built for car-users (which indeed results into even higher density, and parking problems)Originally posted by Breed
Much of the higher density building has to do with policies that restrict or control urban sprawl.
Secondly, I would like to ask Ablarc, the starter of this thread, from which time this area is. Looking at the picture, it seems at least 100 years old, if not 200. In those days there existed some small parts that you could call suburban, but of course they were built in a higher density.
I bet that palace over there is "Le Wal-mart", and the grass fields you see is just green asphalt parking lots
Now seriously: just using the word palace indicates you that it's not really new at all.. easily 200 years old. At least the palace; the rest looks at least 100 years old.
On another topic; a problem France and Chile share is the excessive centralism, although in France it's less; I doubt anybody links France to Paris only, but it's quite close.
You just can't compare "suburbs" from the early 20th century or older, with suburbs of the last 50 years; The first are now probably completely urban; and of course the density was higher, and they were closer to the city; I doubt anybody wanted to walk (or ride in a buggy) 10 miles to go anywhere.
To me this thread is comparing apples with pears.
Maarten, the photo was taken in 1999. Here is the same scene exactly twenty years earlier:
Comparison of the two photos reveals among other things:
1. The square, which had been subjected to use as parking has been made into a park.
2. The street coming into it from lower right has been infilled with proper, new streetwall buildings, though flat-roofed and somewhat horizontal.
3. The streets other side has had a jumble of buildings replaced with a pretty decent set of courtyarded, traditional buildings (purplish gable roofs).
4. Just beyond the big church, a large area has been covered with new streetwall buildings.
5. To the churchs immediate left, a brand-new building links the church with a dormered Renaissance building. In doing so, it combines stylistic elements of both buildings, to produce a convincing and harmonious ensemble and a consistency of scale. (Scale does not mean size or height; it is a function of footprint and the frequency of event on the buildings surface: in other words, the amount of detail. This is where the flat-roofed, horizontal-themed building falls down a bit. Its hard to design a modernist building to be in scale with its surroundings; Modernism has different fish to fry.)
6. Careful examination will reveal further recent interventions; significant numbers of buildings in the newer photo are new; most of the stolid background buildings are 19th Century.
Btw, the suburb is called St. Denis, and the church is the earliest instance of indisputably Gothic architecture; Abbot Suger is said to have cooked it up around 1137. In this abbey church are buried many of the kings of France.
The Metro extends to this suburb a few kilometers outside the peripherique, and it has recently benefited from a light rail line (tramway).
Naturally, it is an absorbed town.
Last edited by ablarc; 01 Jan 2005 at 5:36 PM.
Skeleton, that's exactly right. I see you get the point.Originally posted by SkeLeton
Do you prefer apples or pears?
Originally posted by mgk920
Ah. SHould have recognized it. I actually lived in West Ridge/West Rogers Park for a winter semester one year. when I had the self-delusion that I would make a good electrical engineer. I lived near the corner of Western and Touhy. (2400 block of Fargo Avenue) Beautiful, owner-occupied three-flat.
From what I can tell, the bulk of your complaints with development in the US revolve around the use of the automobile. In Europe, population densities and existing development patterns are very conducive to the efficient implementation of pulbic transit. Because of the provision of reliable public transit, their development follows certain patterns.Originally posted by ablarc
I don't think you can assume that if you develop a certain way, the transit modes will fall into place. I think development occurs based upon transit modes that exist. History bears this out.
Taking the European model and plopping it in Anywhere, USA, just isn't going to work.
Sorry, mgk920 is right. The caption said "evanston" so I took its word, but looking at the map, it's mostly Rogers Park. Evanston is mostly just a continuation thereof though.
"If you think you can or if you think you can't, you're right."Originally posted by Breed
--Henry Ford
Last edited by ablarc; 02 Jan 2005 at 1:21 PM.
Originally posted by jordanb
it's mostly Rogers Park. Evanston is mostly just a continuation thereof though.
Yep... both have the same degree of density. Evanston, like the St-Denis in ablarc's photo, also has a recognizable center.
But what's interesting is that suburban urbanity in Europe isn't just confined to upscale towns like Highland Park and "lifestyle centers." Saint-Denis, the Paris suburb mentioned here by ablarc, is actually quite working-class. It's at the center of France's most diverse département, Seine-Saint-Denis, or simply "93." Its actual claim to fame now is not this beautiful center, but the Stade de France, built for the 1998 World Cup.
Originally posted by drucee
An excellent book on suburban Paris:Roissy Express. Not a very promising view-it makes suburban Paris sound kinda bleak. Not that there are not islands of improvement, like ablarc has brought to our attention.
Originally posted by ablarc
But, part of Henry Ford's "vision" and "Can do" involved armed Pinkerton Guards shooting at his striking workforce (and contributions to the Nazi German-American Bund). Ford subsidiaries can do certainly helped the German war effort, as well. (Were those profits ever confiscated, by the way??)
As exhibited in the recent Oregon election, top-down "can do" planning, at least in the United States, often creates a reaction that will make things worse. One of the factors in the vote, I've read, is the opposition of residents of "suburban" auto-oriented suburbia to the type of mixed-use, higher desnity infill that "planners" like to prteach for everyone. (Plus, the general difficulties associated with ballot box planning, of course)
If that were true, places like Old City, Philadelphia, Quebec City, Old Town Alexandria, and Greenwich Village would have ceased to be viable places to live and do buisness. They would be considered impossible to live in anachronisms. But they haven't. In fact, they are costly, popular places to live. It is not impossible to recreate them. The laws just need to allow it.Taking the European model and plopping it in Anywhere, USA, just isn't going to work.
Way to go, boilerplater. Anyway, it isn't the "European" model; it's the model of those who walk. Environments built for walking are fundamentally the same whether they are in Europe, North America, Australia, South America, Asia or Africa. And they're fundamentally the same regardless of what century they were built in. The human leg hasn't changed much in length, which is why Poundbury, Seaside, Brooklyn Heights, Georgetown, Pacific Heights, Carmel and other walkable places are basically similar.Originally posted by boilerplater
Unwalkable places unsurprisingly date only from the time after wheeled transport became widespread. A place like Boston's present West End or the planned part of Brasilia is unwalkable regardless of the intentions because the buildings are too far apart and have excessive footprints. In Brasilia, an unplanned peripheral town has sprung up, where people walk and prefer to be.
and...popular preferences and perceptions.Originally posted by boilerplater
"How dare you build that dense, walkable neighborhood with apartment buildings near me. This will be an instant slum. Where will they park, and how will the city deal with the congestion? We need more single family houses and green space."
Again, it is not "just" planners' rules that determine why we build cities the way we do. There is deep social buy-in to the sprawl ideal of automotive convenience and spread out land uses.
I'm not saying that it's not possible or that it's not a good thing. I'm saying that you can't take the European model and put it just anywhere in the US and expect it to work. Generally, the only places it will work are places dense enough to support it.... usually older places laid out before the popularization of the automobile. That eliminates much of the US.Originally posted by boilerplater


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The Melbourne Cricket Ground (MCG) is located a short distance from Melbourne's city centre in the Melbourne Sports Precinct at Yarra Park, which also includes the Rod Laver Arena, Hisense Arena and AAMI Park. With a total capacity of 100,000 people, the Melbourne Cricket Ground is the largest stadium in Australia, the tenth-largest stadium in the world, and the world's largest stadium for playing cricket.
The Melbourne Cricket Ground has been the scene of many great sporting events and 'firsts' in Australian sporting history since being built in 1853, just 19 years after the founding of the City of Melbourne itself.
It is the home of the Melbourne Cricket Club (MCC), the oldest sporting club in Australia. In 1877 the first game of Test cricket in history was played between Australia and England on the Melbourne Cricket Ground. In 1971, the ground hosted the first One Day International cricket match. The Boxing Day Test match on Boxing Day (26 December) each year attracts huge crowds. In winter, it serves as the home of Australian Rules football (AFL). The stadium fills to capacity for the AFL Grand Final in late September.
Many international rock concerts have also been held at the MCG. The first rock concert to be held at the ground was David Cassidy in 1974. David Bowie, Paul McCartney, U2, Madonna, The Rolling Stones, the late Michael Jackson, Elton John and Billy Joel have also performed here.
The MCG's most famous moment in history was as the main stadium for the 1956 Olympic Games. The Opening and Closing Ceremonies of the 2006 Commonwealth Games and athletics events were held at the MCG.
A behind-the-scenes tour of the MCG reveals more than 150 years of Australian sporting excellence. Combine your MCG tour with a visit to the National Sports Museum which features thousands of sporting artefacts showcasing the highlights of Australia's sporting history, such as cricket legend Don Bradman's baggy-green cap; Cathy Freeman's gold medal-winning running suit; and Ian Thorpe's full body swimsuit. It also houses a permanent gallery dedicated to horse racing, as well as the Australian Gallery of Sport and Olympic Museum, Sport Australia Hall of Fame, Australian Cricket Hall of Fame and Australian Football Hall of Fame.
Birrarung Marr, on the north bank of the Yarra River between Federation Square and the National Sports Precinct, was named by the Wurundjeri Aboriginal people who originally inhabited the area. Designed to host some of Melbourne's major events and festivals, Birrarung Marr is a place where you can relax or take part in a variety of activities against the backdrop of the Melbourne city skyline and the Yarra River.
The MCG is located about 1km from the city centre. The William Barak pedestrian bridge links Yarra Park with the city. There are two train stations close to the stadium. Jolimont (otherwise known as MCG Station) is a five-minute walk through to the ground. Other transport to the arena includes tram, bus and water taxi.


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Industries Environmental Documents
Final Environmental Impact Statement for the Relicensing of the Boundary Hydroelectric Project No. 2144-038 and the Surrender of the Sullivan Creek Project No. 2225-015
Issued: September 9, 2011
Commission staff prepared a final Environmental Impact Statement (EIS) for the relicensing of the City of Seattle's existing 1,003-megawatt Boundary Hydroelectric Project (Boundary Project), and the surrender of the Public Utility District No. 1 of Pend Oreille County's (District) Sullivan Creek Project (operated as a storage project). The Boundary Project is located on the Pend Oreille River in Pend Oreille County, Washington. The Sullivan Creek Project is located on Sullivan Lake, and Sullivan Creek and Outlet Creek, tributaries to the Pend Oreille River that empty into the Boundary Project reservoir. Both projects occupy lands within the Colville National Forest.
On September 29, 2009, the City of Seattle, Washington (Seattle) filed application to relicense the Boundary Project. On March 29, 2010, Seattle and the District jointly filed an offer of settlement, consisting of two comprehensive settlement agreements, a joint explanatory statement and a request to consolidate the processing of Seattle's relicensing of the Boundary Project with the District's surrender of its license for the Sullivan Creek Project. Subsequently, on April 2, 2010, the District filed an application to surrender its license for the Sullivan Creek Project.
The Boundary settlement agreement includes obligations for evaluating and providing fish passage for resident salmonids, reducing fish entrainment, improving aquatic habitat, stocking fish for recreational purposes, conserving native fish, groundwater well-decommissioning, acquiring and managing land for wildlife, and other measures for recreation and cultural resource enhancement and protection. Under the Sullivan Creek settlement agreement, the District would retain and operate under a Forest Service Special Use Authorization the Sullivan Lake dam and lake; install a new cold-water release intake at Sullivan Lake dam; remove Mill Pond dam, restore the site and the stream channel, and conduct short-term monitoring and maintenance to ensure the restored channel is functioning as designed. These settlement agreements, and the measures contained therein, are intended to provide significant benefits to resources within the Pend Oreille River and its tributaries, while retaining Seattle's operational flexibility and reducing costs of the Sullivan Lake Project surrender on Pend Oreille rate payers.
The final EIS assesses the effects of both settlement agreements and staff modifications to those agreements. The staff's recommendation is to relicense the Boundary Project as proposed, with certain modifications and additional measures to improve administration of the license. The staff also recommends approval of the surrender application as proposed, with certain modifications to mitigate adverse effects to cultural resources and improve Commission oversight and administration of the surrender.


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Tag Archives: Skoda Superb
It is a hush-hush beauty, yes, the upcoming Skoda Superb 2016!
When we don't know the complete story, it somehow stays in our mind. Doesn't it? We just can't stop thinking about it night and day and it is as if you'd trade your peace of mind to just know more, to add some fuel to your imagination that is already driving you crazy. Well, it is no different for the upcoming Skoda Superb 2016. The current model that has been around for quite some time, well, it was well received and all. But perhaps the company wanted something more, something, fiery, something that would have left the world wanting for more. It is because of this desire that the company has worked up a model for 2016 and it is not letting on much, even officially.
The only thing, perhaps, that has been confirmed is that it is definitely, definitely Skoda Superb that they are working upon and very innovatively at that. But that is all we know. Everything else is under their hats and that is exactly what has gotten us thinking! What could be so special about this one, what are the additions made to this already gorgeous vehicle, what could possibly be the personality changes! The list, it just, doesn't get over and even though we tried getting a whiff of the details, we didn't have much luck. But as they say, where there is a will, there is a way, so we have culled up for you some details that are going to let you take a closer look at the upcoming Skoda Superb 2016!
From what we have gathered so far is that this project, so to say, is designer. Yes, that is absolutely true. The designer Jozef Kaban has successfully put it together and very innovatively at that. This in itself has listed the curtains a little bit, if not entirely. For all of those who have been following the motor world closely would know that he is a guy of finesse, he works his magic with smaller details rather than attempting drastic changes that catch you unprepared. This time around, we are all set for he is going to produce our way – chances are he is working his wonder on VisionC concept! Almost certainly the way he has envisioned Skoda Superb 2016 is with some classy visual charm, not going totally overboard, keeping it subtle yet irresistible as ever.
So, they are saying that the upcoming Skoda Superb 2016 will be not a world apart from the existing model. No, that is not the idea this time. It is a very distinct yet subtle demarcation that has been planned. So, be prepared to see the new delight in almost the same body style as the previous one. However, while the liftback stays, as does the wagon body, this one has a 2.0-litre TDI unit that exhales 190 horsepower. The Volkswagen Passat model closely inspires it but we will stop right here for you got to talk under breath for this secretive beauty and just wait for it!


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Monday, January 21, 2013
Apple IPhone Suppliers Decline on Report Orders Cut by 50%
Posted by Zen Nguyen at 8:54 AM Labels: IPHONE, TECH WORLD, TechLife
Sharp Corp. (6753) and other Apple (AAPL) Inc. suppliers declined in Asia trading after the Nikkei newswire said orders for iPhone 5 parts had been cut about 50 percent following lower-than-expected sales.
Sharp, which makes display panels for the iPhone 5, fell 2.7 percent to close at 321 yen in Tokyo. Samsung Electronics Co. (005930), which supplies Apple and makes its own competing phones, declined 2.6 percent in Seoul. Speaker-maker AAC Technologies Holdings Inc. (2018) dropped 2.8 percent in Hong Kong.
Apple hit an 11-month low in New York yesterday after the Nikkei report underscored concerns about iPhone 5 sales and the wider smartphone market. Ex-Chief Executive Officer John Sculley also said today the Cupertino, California-based company needs to develop cheaper phones to boost sales in emerging markets.
Slower iPhone demand "will inevitably have a negative impact on component suppliers," said Park Hyun, an analyst at Tong Yang Securities Inc. in Seoul. "The center of growth in the market is moving toward the mid-end segment."
Apple intended to order parts for about 65 million iPhone 5s this quarter, Nikkei said, citing unidentified executives at parts suppliers. Steve Dowling, a spokesman for Apple, declined to comment.
IPhone Sales
The suppliers' declines today were limited by earlier reports the iPhone 5 was trailing sales targets and that Apple was cutting production, said Keita Wakabayashi, an analyst at Mito Securities Co. in Tokyo. The phone maker cut production about 30 percent last month, USB AG analyst Steven Milunovich wrote in a note yesterday.
"This is not entirely a new story," Tokyo-based Wakabayashi said. "That's why stocks aren't plunging dramatically."
Apple may have pared iPhone production to rebalance inventory or because of lower consumer demand, according to Milunovich. Order cuts may also be due to suppliers becoming more adept at assembling the latest iPhone, reducing the need for excess inventory, he said.
Milunovich's projection for 25 million iPhone 5 units to be sold in the quarters ending in December and in March will still be exceeded under the scenario Nikkei reported, he said.
Exaggerated Reports
BOCI Research Ltd. analyst Tony Yang in Hong Kong said checks with Apple suppliers failed to produce any signs of "a huge iPhone 5 shipment drop." Barclays Plc analyst Jones Ku also said there were no indications of a large order cut for speakers made by Shenzhen, China-based AAC.
"The actual order cut for iPhone 5s in the first quarter is exaggerated," Ku said in Hong Kong. "The large cut for displays is mainly due to the over-purchase of displays in the fourth quarter."
AAC spokesman Louis So declined to comment.
LG Display Co. (034220) fell 3.5 percent in Seoul. In Taiwan, Hon Hai Precision Industry Co. (2317), which assembles iPhones, dropped 3.4 percent and circuit-board maker Zhen Ding Technology Holding Ltd. (4958) declined 3 percent.
Sharp is cutting production at a plant making iPhone panels in Kameyama, Japan, to about 40 percent of capacity from close to 100 percent in the previous three months, the Nikkei said. The company gets 3.4 percent of sales from Apple, its biggest customer, according to data compiled by Bloomberg. Sharp last year said there was "material doubt" about its ability to survive because of tumbling TV sales.
Miyuki Nakayama, a spokeswoman for the Osaka-based company, declined to comment yesterday, citing Sharp's policy of not commenting on customers. Nam Ki Yung, a spokesman for Samsung Electronics, and Claire Ohm, a spokeswoman for LG Display, declined to comment.
Low-Cost Phones?
Sculley said in an interview with Bloomberg TV the phone- maker needs to overhaul its supply chain to meet demand for lower-cost smartphones in emerging markets. The U.S. and European markets offer little room for growth because they are saturated, he said.
"Apple needs to adapt to a very different world," he said. "As we go from $500 smartphones to even as low, for some companies, as $100 for a smartphone, you've got to dramatically rethink the supply chain and how you can make these products and do it profitably."
To contact Bloomberg News staff for this story: Edmond Lococo in Beijing at email@example.com; Mariko Yasu in Tokyo at email@example.com
To contact the editor responsible for this story: Michael Tighe at firstname.lastname@example.com
From Bloomberg
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Raiders wide receiver Tim Brown and defensive lineman Warren Sapp are among the 15 modern-era finalists in voting for the Pro Football Hall of Fame.
Sapp is among the four first-year-eligible nominees. Brown made the cut for the final 15 last year before being bypassed.
The 15 modern-era finalists were determined by a vote of the Hall's Selection Committee from a list of 127 nominees that earlier was reduced to a list of 27 semifinalists, during the multi-step, year-long selection process.
Curley Culp and Dave Robinson were selected as senior candidates by the Hall of Fame's Seniors Committee. The Seniors Committee reviews the qualifications of those players whose careers took place more than 25 years ago.
The final vote takes place the day before the Super Bowl, with anywhere from four to seven players being selected for induction in early August.
Brown played for the Raiders from 1988-2003 and concluded his NFL career with the Buccaneers in 2004. This is the fourth year he has been on the ballot.
Here is Brown's bio:
Wide Receiver/Kick Returner/Punt Returner … 6-0, 195 … Notre Dame … 1988-2003 Los Angeles/Oakland Raiders, 2004 Tampa Bay Buccaneers … 17 seasons, 255 games … Heisman Trophy Winner … Selected by Raiders in 1st round (6th player overall) of 1988 draft … As rookie led NFL in kickoff returns, return yards, and yards per return average … Led NFL in receptions, 1997 … Set Raiders franchise records for receptions, receiving yards, and punt return yards … At time of retirement his 14,934 receiving yards were second-highest total in NFL history; 1,094 receptions were 3rd; and 100 touchdown catches were tied for 3rd … Also gained 190 rushing yards; 3,320 punt return yards, 3 fumble return yards; 1,235 kickoff return yards … Total of 19,682 combined net yards, 5th all-time at time of retirement … Scored 105 total touchdowns (100 receiving, 1 rushing, 3 punt returns, 1 kickoff return) … Voted to Pro Bowl nine times, 1989 and 1992 as kick returner, 1994-98, 2000 and 2002 as a receiver … All-Pro choice as a kick returner, 1988 … All-Pro wide receiver, 1997 … Was named All-AFC as a kick returner, 1988, punt returner, 1991, and wide receiver, 1993, 1994, 1995, 1997 … Born July 22, 1966 in Dallas, Texas.
Here is Sapp's bio:
Defensive Tackle … 6-2, 300 … Miami (FL) … 1995-2003 Tampa Bay Buccaneers, 2004-07 Oakland Raiders … 13 seasons, 198 games … Selected in first round (12th player overall) by Tampa Bay in 1995 NFL Draft … Instant starter … Named to All-Rookie Team, 1995 … Amassed 96.5 career sacks despite playing on interior of defensive line … Recorded double-digit sack totals four times … Had more than one sack in a game 23 times … Named 1999 NFL Defensive Player of the Year after helping lead Tampa Bay to first division title in 18 years … Registered 12.5 sacks, 54 tackles, three forced fumbles, and recovered two fumbles, 1999 … Recorded career-high 16.5 sacks, 2000 … Started in two NFC championship games, one Super Bowl … Recorded two tackles, one sack, two passes defensed, and forced fumble in Bucs' 48-21 win over Raiders, Super Bowl XXXVII … Additional career statistics include four interceptions, two touchdown receptions … First-team All-Pro four straight times (1999-2002) … Second-team All-NFL in 1997, 1998 … All-NFC five times … Selected to seven Pro Bowls … Named to NFL's All-Decade Teams of the 1990s, 2000s … Born December 19, 1972 in Orlando, Florida.


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Photodynamic Therapy Mediated by Topical Application of 5- ALA for the Treatment of Actinic Keratoses
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT00814528
Recruitment Status : Withdrawn (The study never started due to the Principal Investigator leaving the institution)
First Posted : December 25, 2008
Last Update Posted : September 10, 2018
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
|Condition or disease
|Actinic Keratosis
|Drug: 5-ALA plus Blu-Light Drug: 5-FU, Imiquimod or treatment with cryotherapy
|Not Applicable
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|0 participants
|Intervention Model:
|Parallel Assignment
|None (Open Label)
|Primary Purpose:
|Official Title:
|Photodynamic Therapy Mediated by Topical Application of 5- ALA for the Treatment of Actinic Keratoses
|Study Start Date :
|November 2007
|Actual Primary Completion Date :
|September 2009
|Actual Study Completion Date :
|September 2009
Experimental: 1
Application of 5-ALA PDT to some lesions on skin with "Blue U" light source (417 nm).
Drug: 5-ALA plus Blu-Light
20% 5-ALA ampoules will be crushed and prepared for application after shaking for 3 minutes. Topical ALA will be applied liberally on skin with extra pressure on lesions. Incubation of ALA will take place for 0-3 hours. Exposure to Blue U light source (417 nm) (DUSA), will be performed for Actinic Keratosis for 15 minutes. Application of combination light sources will be performed when lesions are traced with one pass of Pulsed dye laser (595 nm) (Candela) followed by exposure to Blue U light source for 5-8 minutes pending response.
Experimental: 2
5-FU, Imiquimod or treatment with cryotherapy to lesions on the skin.
Drug: 5-FU, Imiquimod or treatment with cryotherapy
Cryotherapy will be performed on lesions only every 2 week intervals. Application of Imiquimod will be done on the treated skin area 5 days weekly for 4-6 weeks. 5-FU will be once daily on the treated areas 4- 6 weeks. Responses will be monitored every 2 weeks.
- Actinic keratosis /incomplete therapy and reoccurence [ Time Frame: 18 months ]
- Erythema [ Time Frame: 2 weeks post therapy ]Early skin responses 2 weeks post therapy (erythema, scaling, post inflammatory skin changes, fine wrinkling of skin, mottled pigmentation)
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years to 95 Years (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- 18-95 years old
- Diagnosied with actinic keratoses.
Exclusion Criteria:
- Patients who have had Isotretinoin therapy less that 1 year prior to screening.
- Patients who have an adverse reaction to light exposure (for example photo- exacerbated seizures).
- History of porphyria
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00814528
|United States, Illinois
|The University of Chicago
|Chicago, Illinois, United States, 60637
|Principal Investigator:
|Maria Tsoukas, MD
|University of Chicago
|Responsible Party:
|University of Chicago
|ClinicalTrials.gov Identifier:
|NCT00814528 History of Changes
|Other Study ID Numbers:
|First Posted:
|December 25, 2008 Key Record Dates
|Last Update Posted:
|September 10, 2018
|Last Verified:
|September 2018
Keywords provided by University of Chicago:
actinic keratosis
skin lesions
Additional relevant MeSH terms:
Aminolevulinic Acid
Keratosis, Actinic
Skin Diseases
Precancerous Conditions
Adjuvants, Immunologic
Immunologic Factors
Physiological Effects of Drugs
Antineoplastic Agents
Interferon Inducers
Photosensitizing Agents
Dermatologic Agents


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AAPT Collaborative Projects
AAPT sponsors or participates in many special projects designed to enhance the teaching of physics and astronomy. Many projects are funded in part by the National Science Foundation, as well as by partner organizations such as the American Physical Society, the American Institute of Physics and the Society of Physics Students. Details of the projects with which AAPT is currently involved are located here.
Ongoing Projects
- National Task Force on Undergraduate Physics (NTFUP)
- Physics Teaching Education Coalition (PhysTEC)
- Physics Teaching Resource Agents (PTRA)
- Powerful Ideas in Physical Science (PIPS)
- Preparing Future Physics Faculty
- SPIN-UP.US Regional Workshops
Future Projects
If you are interested in developing a collaborative project please contact Beth Cunningham or Robert Hilborn.
In August 2011, the AAPT Executive Board approved updated guidelines for anyone considering submitting a proposal to NSF, Department of Education, etc.


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Honestly, these are empanada impostors. Authentic empanadas typically come stuffed with raisins, boiled egg, and sometimes green olives. Mine are really more like carne asada taco pockets. However these beef empanadas with avocado cream sauce were the highlight of our culinary week.
I hope I don't offend anyone by using the term loosely, but "empanadas" is such a fun word to say. It just rolls off the tongue easier than "Mexican spiced meat pockets".


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Japanese yen
The Japanese Yen (pronounced "en" in Japanese) is the official currency of Japan. In use since 1871, the currency is the third most traded currency in the world. The currency's coins include denominations of ¥1, ¥5, ¥10, ¥50, ¥100 and ¥500 and banknotes are available in ¥1000, ¥2000, ¥5000 and ¥10000. One Yen is equal to 100 Sen and 1000 Rin. To protect users from counterfeit banknotes, Japanese authorities take great care to ensure all banknotes are kept clean and undamaged by examining all notes that are returned to the bank and replacing and destroying any that are not of a particular standard. The ¥5 and ¥50 coins feature a hole in the center.


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INGLEWOOD, Calif. (June 3, 2012)—Making his first start away from Golden Gate Fields, Nonios proved he belonged in graded company with a 15-1 surprise in the $100,000 Affirmed Handicap (video) Sunday at Betfair Hollywood Park.
Under jockey Martin Pedroza, the 3-year-old son of Pleasantly Perfect waited for room while full of run approaching the stretch, found an opening between horses with less than an eighth of a mile to run and held favored Liaison safe.
Owned by Green B. Smith, Jr and trained by Hall of Famer Jerry Hollendorfer, Nonios, who is out of the Touch Gold mare Stylish Manner, won for the third time in four starts and increased his earnings to $99,000. The final time for the 1 1/16 miles over Cushion Track in the Grade III was 1:42.99.
The half-length victory was the second in the Affirmed for Hollendorfer, who scored previously with Eye Of The Tiger in 2003.
Nonios, whose only loss came versus older horses in an optional claimer over Tapeta April 7, paid $33.80, $10 and $4.60.
"I saw the tape when Russell Baze rode this horse (a six length win March 10 at Golden Gate),'' said Pedroza, who had won the 2008 Affirmed with Two Step Salsa. "He was like Silky Sullivan.
"I don't know what kind of horses he beat up there, but if you watch that horse on the computer, you'll see what I'm talking about. He's a very smart horse and Jerry told me to ride him with confidence. In the stretch, a hole opened up and he just attacked it.''
Wide throughout as the even-money choice in his initial start since finishing sixth in the Kentucky Derby May 5, Liaison, the 122-pound highweight, paid $3 and $2.40 while finishing 1 ¼ lengths in front of 2-1 second choice Holy Candy.
The loss was the first in three starts over Cushion Track for Liaison. The Indian Charlie colt won the Real Quiet Stakes and Grade I CashCall Futurity as a 2-year-old for Hall of Fame trainer Bob Baffert and owner Arnold Zetcher.
"I tried to save as much ground as I could, but it was tough from the outside post,'' said Rafael Bejarano, Liaison's regular rider. "It looked like Nonios had a lot of run, so I tried to get first jump. That horse just kept running. My horse had no excuse.''
In his first start since finishing fourth in the Grade I Blue Grass Stakes April 14 at Keeneland, Holy Candy wound up 1 ¼ lengths in front of Unusual Heatwave. The show price on the gray son of Candy Ride was $2.60.
Completing the order of finish were lingo and pacesetter Gun Boat, who is also trained by Baffert. American Act was scratched Saturday.
Earlier in the day, Majestic City, a two-time stakes winner at Betfair Hollywood Park as a 2-year-old, finished third in his 2012 debut for owner Jeff Bloom and trainer Peter Miller.
A son of City Zip who won the Willard Proctor Memorial and Grade III Hollywood Juvenile Championship last year, Majestic City finished 2 ¼ lengths behind Rauschenberg.
It was the first race for Majestic City since he finished 10th as the 3-1 favorite in the Grade I CashCall Futurity last Dec. 17.
The half-length win by Rauschenberg in the $62,000 allowance was his fourth in five starts on the Betfair Hollywood Park grass. The 5-year-old Grand Slam gelding is owned by Gary Broad and trained by Marty Jones. Ridden by Garrett Gomez, the Kentucky bred covered the six furlongs in 1:08.88. Obviously, the even-money favorite, was a troubled second.
Racing resumes Thursday. Post time is 1 p.m.
The Hollywood Park Casino will be open for dark day simulcasts Monday, Tuesday and Wednesday. Admission is free. The first simulcast is at 10:10 a.m.
Copyright © 2009-2012, Hollywood Park. All rights reserved. Site design by Love Has No logic Design Group


text: Brrr! Here at BlindSaver, the chill of the fall is in the air, and with it the knowledge that the season is here. The season of Halloween parties, Christmas Dinners, and New Year's count downs. Of extended family stays featuring big dinners and big messes. So why not choose a window covering that can stand up to all that? Kristan Cunningham's exclusive line of roller shades are made of 100% Polyester, so spills wipe off easily with just a damp rag. Plus, with a wide range of unique patterns and familiar colors this collection will fit in any home during any season.


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A Plethora of Ways to Add Color in the Kitchen
Kitchens and bathrooms aren't always colorful places. We flirted with wildly colored kitchens in the 50s and 60s, got burned, and have been a bit leery ever since. But maybe it's time to rethink that. The kitchen, really, is the heart of the 21st century home, and why should that heart be wan and colorless? We've got oodles of ideas for adding color to your kitchen, for everyone from the completely color-phobic to the completely comitted.
To get the biggest impact, add color to the thing that takes up the most space in your kitchen — your cabinets.
1. A lovely green kitchen by Barbara Bestor, via Desire to Inspire.
2. You don't have to paint all the cabinets — just lower cabinets will do it, as this room from Beautiful Kitchens demonstrates. Or you can paint just the upper cabinets, like Lee did in this Before and After.
3. Of course, on the other hand, you could always paint both the cabinets and the walls. Just make sure it's a color you really really like. Super yellow kitchen by Design Intervention, via Singapore Home & Decor.
4. Elsie of A Beautiful Mess added color to the inside of her cabinets. It's a beautiful secret that only you will know about.
5. Can't decide? Make your kitchen every color. Magnus Anesund for Elle Interior.
For even more colorful kitchen cabinets (seriously — cabinets in every color of the rainbow), click here.
I used to work at an architecture firm. In our library, we had boatloads of countertop samples, many of them in outlandish colors like orange and bright yellow. Who would ever use this in a kitchen? — I found myself thinking. Well, the answer is: really brave and stylish people. Here is a kitchen with a hot pink countertop, and — surprise! — it is gorgeous.
1. Go bold. A pink countertop and walnut veneer just works. Ursula Mayer for Schorn & Groh via Bungalow.
2. A yellow countertop is just right in this minimal kitchen from Zeta Studio Architects via Home DSGN.
3. A Turquoise countertop makes a big impact in a small kitchen from Kathleen Hay Design (via DecorPad).
4. Pink quartz in the kitchen? Yes, a thousand times yes. Bonus points for the backsplash. From HGTV.
This is, of course, the most obvious way to add color to any room. The problem is that there's really not a lot of 'wall' in most kitchens. Are you very committed? Trade in your upper cabinets for open shelving, and embrace some glorious hue.
1. How happy would you be to cook in this kitchen? From Anthology Magazine.
2. If bold color isn't your thing, try a soft pink. From Hogar Util.
3. Domino via Paloma81.
4. Sooz Gordon's home is full of rich color, and her kitchen is no exception.
5. For low-comittment color, paint the space above your tile (or the space above the cabinets). Photo from Stadshem, via La Maison d'Anna G.
And in the photo at the very top of this post (from Design*Sponge), the homeowner painted her kitchen in a whole array of bright colors. I bet that's a real pick-me-up in the morning.
Don't forget the floor. Commitment shy? Try a rug. A sturdy one, of course.
1. A green floor, spotted in Ralph & Julie's Spacious Altbau in Berlin.
2. A colorful rug saves the day! Some colorful bottles and cookbooks help out. From Plaza Interior.
3. Bonus points for color on the ceiling AND the floor. Lina Östling for Hus & Hem via From Scandinavia with Love.
Don't forget the CEILING. There aren't any pesky cabinets up there to get in the way — you'll be bathing in gently reflected color in no time. Image from House and Home.
If you're a bit color-shy, adding a colorful backsplash is a great way to liven up an otherwise staid kitchen.
1. A painted backsplash could work in a kitchen that doesn't see a lot of heavy lifting — just make sure to use a high-gloss, heavy-duty paint. Crown Paints via Easy Living.
2. That backsplash pretty much makes the kitchen, no? From Fredrik Paulsen (photography by Märta Thisner).
3. Stripes of contrasting tile — colorful, unusual, beautiful. Made a Mano tile, via Happy Interior and Design Crisis.
4. A beautiful light blue from Desire to Inspire.
5. Okay, so this is actually a bathroom (the bathroom of the Viceroy Hotel in Santa Monica, specifically, spotted on Justina Blakeney's blog). I am posting it anyway because it's gorgeous. Also, subway tiles turned sideways? That's a new thing.
Low-committment, high impact. If you're going to hang a very large piece, you will need to find a spot without cabinets, but you can also squeeze in smaller pieces in between upper and lower cabinets, or prop them on top of the upper cabinets, as Arthur and Katherine have done. The photo above is from a Paris apartment we spotted on Trend Home. Bonus points for the pink Smeg and red dishwasher.
If you're going to choose this option, you might just go ahead and buy a Smeg. C'mon, you know you want to.
1. The Kitchen Cousins designed this beautiful kitchen with a blue stove and refrigerator for Jeannie Mai and Freddy Harteis. See more of their home here. The appliances are by Big Chill: they make a dishwasher, stove and refrigerator in 8 different retro colors.
2. A stove and refrigerator from Blue Star liven up this white kitchen. (And the house is for sale!)
3. A tiny pink Smeg adds just the right amount of color to this tiny kitchen from Klikk via Planete Deco..
4. A lovely yellow stove (looks like another Blue Star — they come in about a billion colors) with coordinating art in the home Bobbie Burgers, as seen on Escapade.
5. Lidia Bastianich looks proud of her red stove. I would be, too. From Food Network.
For even more colorful appliance inspiration, click here.
So there you go. Kitchens will never be boring ever again.
(Images: as linked above)


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Stop worrying about over-eating. Your pediatrician is right. His weight will level off eventually.
Stop worrying about over-eating. Your pediatrician is right. His weight will level off eventually.
K. Sophia - Mama to my little lactivore, the amazing Mr. X (11/10).
Stop worrying, and continue to feed on demand. It's normal for EBF babies to gain weight really, really fast in the first 6 months or so. A pound per week is not unusual in the early weeks. But after a few months, usually sometime around the middle of the first year, weight gain tends to slow way down as baby becomes more mobile and starts putting his calories into action instead of packing them on as fat. Both my girls were born small, shot up to the very top of the charts for weight, and then dropped back down the percentiles at around 4-8 months.
Any tips on how to nurse in an Ergo? He is much higher than my boob and when I've done it, I have to really lower him and lift my boob into his mouth.
I never could nurse in an Ergo. My tall babies combined with my anatomy precluded such. Lowering baby to my breast put baby's weight at a place where he hurt my back. I found a Maya wrap easier myself.
Mama to my all-natural boys: Ian, 9-4-04, 11.5 lbs; Colton, 11-7-06, 9 lbs, in the water; Logan, 12-8-08, 9 lbs; Gavin, 1-18-11, 9 lbs; and an angel 1-15-06
18+ months and for Gavin, born with an incomplete cleft lip and incomplete posterior cleft palate
Sealed for time and eternity, 7-7-93
Always babywearing, cosleeping and cloth diapering. Living with oppositional defiant disorder and ADHD. Ask me about cloth diapering and sewing your own diapers!
and i could only nurse in a ring sling, and still always had to hold my breast with one hand. better than nothing, though! i could go on walks.
Nursing, pumping, cloth-diapering, babywearing, working professor mama with the awesomest SAHD ever.
I have small breasts (even if I held my breast in my hand, it wouldn't change the height of the nipple), so I don't need to drop my baby so low in the Ergo. I still nurse in it at 18 months, but it is becoming more difficult as he's getting taller. I think it is much more difficult if you have larger breasts.
Either a wrap or a sling would probably be better because it is easier to adjust your baby's position. I have a Moby, and the only thing I like about it is that it is very adjustable. I've heard that woven wraps are much better than the stretchy ones. I loved my ring sling too when mine was little.
It's worth the investment in something that will work. Getting out of the house is all around good for you.
K. Sophia - Mama to my little lactivore, the amazing Mr. X (11/10).
Hey there... I wanted to tell you that my LO had silent reflux too, and nursed constantly for the first 2-3 months. He would nurse so much that he would end up spitting it all up - it was unreal the amount he would throw up. (he did that 2 times). I also felt I could not leave the house because it wasn't like he gave hunger cues, he cried to nurse because he was in pain. IT DOES GET BETTER!!!! Tummy time helped, once he started sitting up it dramatically improved. We did the nursing in elevated positions, no laying down until at least 30 min after he ate, sleeping elevated. I soooo wish I had used a sling because I have heard so many times after the fact that it is a huge help for reflux babies. We spend many many many evenings carrying LO around in odd positions that were comfortable for hm to help releive his pain.
My LO was also a big boy... he gained quickly and very well. My doctor was never concerned either.... he started leveling out around 9-10 months. I can tell you that nursing my reflux baby was a life-saver for him and I both. It was difficult at times but he needed it. We did use a pacifier for a little while - but he wanted no parts of it by 6 months. And even then, he would rarely take it.
Hold the course momma... your doing well. This too shall pass and you will just look back at it as an experience you and your LO made it through together.
FT working momma to a 9/11/10 busy boy and 11/13/12 happy little man.
Also wife to hubs since 8/23/08, bonus momma to H (girl) -99 and G (boy)-03
While you may feel housebound now, it is temporary!! It will get better. Your baby my nurse more often because it makes him feel better when he does. Denying him nursing could cause him discomfort with his reflux. Be thankful that you have a convenient, effective way to comfort your baby!
It will get better, you will get out more and there will be a day where you'll look back on these days and smile.
Mommy to our DD1 early bird (34 weeks, 2 days, 7lbs, 14oz)! Oct. 2nd, 2008 Emergency C-Section, Frank Breech, HEALTHY Girl!
Weaned @ 17 months
Our DD2 early bird (37 weeks, 3 days, 7lbs, 12oz) Aug. 10th, 2010 Our Successful VBAC, growing like a bad weed!
Weaned @ 15 months
Our DD3 early bird (37 weeks, 3 days, 7lbs, 6oz) Feb. 16th, 2012 Our 2nd VBAC and lightening speedy birth!
Loving being a Mom of 3, 40 months apart!!
I might have a little additional personal perspective to help put your mind at ease - we had the opposite problem with weight (LO had SLOW weight gain and by the time he was 10 days old a hospital-based LC was trying to push formula supplementation - yes, I stopped going to her!) but he exhibited some of the same habits of taking a long time at feeds - sometimes probably nursing for comfort instead of getting milk out which I think caused supply issues for me. We had our challenges, but he is growing steadily now at 8.5 mo and the extra-long, all-day feeds stopped so many months ago I don't remember when it was.
So I just wanted to say that a) yes, to echo a PP it does get better and much easier and you will get outside again, so hang in there! and b) this is just an observation, but I get the feeling that *some* medical professionals have Goldilocks Syndrome (they always have issues with babies being "too big" or "too small") and will stress you out if your baby isn't perfectly average in weight gain. What they don't seem to think about is that "average" on a chart doesn't really equate to "normal" - and the "average" is just a midpoint between data from many, many babies from all over the weight spectrum. If your baby is getting a clean bill of health otherwise and seems happy overall, I agree you should trust your instincts! And continue to be your loving-mama-self!
Wow thanks for all of the encouraging words and wisdom. I only wish I had this forum in the early and painful weeks of BF. BF is one of the most difficult things I have ever done. He was tongue tied, still doesn't have a great deep latch no matter what I do, and yet here we are at almost 11 weeks and he's 101 percentile in weight. I am trying to let go of perfection: maybe he will never have a non clicky latch but I can deal with it and am hoping that as he gets even bigger he will naturally open wider.
Again thank you for sharing your experiences. Today has been a much better day. I have resolved to ignore advice that runs counter to everything I have read and been told.
I do think that when he slows down his sucking, I shouldn't feel guilty about pulling him off if time doesn't permit. Like in the dead of night when we both need to get back to bed. What do you think?
I am worried that he can only fall asleep after feeding and being held. Is this something he will grow out of? There will be a time when that won't be possible all the time. I love feeding and holding him it would love to hear your wise experiences.


text: UFDC Home | Help | RSS Title: School and Residence Building for Francisco Sugar Company, Plans and Section. Drawing No. 1 CITATION ZOOMABLE MAP IMAGE Full Citation STANDARD VIEW MARC VIEW Permanent Link: http://ufdc.ufl.edu/UF00016541/00001 Material Information Title: School and Residence Building for Francisco Sugar Company, Plans and Section. Drawing No. 1 Physical Description: 1 map : ; 58 x 87 cm. Scale: Scale 1:96 Language: English Publication Date: 1952 Subjects Subject: Sugarcane -- Maps -- Cuba ( lcsh )Sugar -- Manufacture and refining -- Maps -- Cuba ( lcsh )Maps -- Cuba ( lcsh ) Genre: government publication (state, provincial, terriorial, dependent) ( marcgt )single map ( marcgt ) Spatial Coverage: Cuba Notes Summary: Depicts blueprint plans and section view of the school and residence building for the Francisco Sugar company. Francisco, Cuba. Statement of Responsibility: Caldwell and Scott Inc. General Note: Series 83, BE-4. Drawing No. 1. Funding: Funded in part by the University of Florida, the Florida Heritage Project of the State University Libraries of Florida, the Institute for Museum and Library Services, and the U.S. Department of Education's TICFIA granting program. Record Information Bibliographic ID: UF00016541 Volume ID: VID00001 Source Institution: University of Florida Holding Location: George A. Smathers Libraries, University of Florida Rights Management: All rights reserved, Board of Trustees of the University of Florida. Resource Identifier: aleph - 003513320 Contact Us | Permissions | Preferences | Technical Aspects | Statistics | Internal | Privacy Policy © 2004 - 2010 University of Florida George A. Smathers Libraries.All rights reserved. Acceptable Use, Copyright, and Disclaimer Statement Last updated October 10, 2010 - - mvs


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The Ford Motor Co. display at the Detroit auto show is a theatrical production.
Ford hired eight actors to portray company founder Henry Ford for the duration of the show, actor Jordan Whalen says.
It's part of the automaker's celebration of the 150th anniversary of Henry Ford's birth.
There are young Henrys, like Whalen and David O'Donnell, and there are older Henrys. The actors are in costumes similar to what Henry Ford would have worn in the early 1900s. They are stationed in front of Ford's oldest surviving production car, a 1903 Model A, near the front of the Ford stand at Detroit's Cobo Center.
Chairman Bill Ford recently bought the 1903 car at auction. It's the third car Henry Ford built; the first two can't be located and are believed to have been scrapped, a company spokeswoman says.
The spokeswoman says Henry Ford actually worked on this vehicle, and its sale in 1903 was critical to his company. Ford only had $250 left in the bank then, and if he hadn't sold these three cars there wouldn't be a Ford Motor Co. today, the spokeswoman says.
To educate the public about the company's history, the actors will walk visitors around the Ford display retelling key parts of the company's history in first-person narrative.
"I'll talk about the 1.6-liter EcoBoost engine today and how that differs from the 1.6-liter engine I built in the 1903 Model A, which was a two-cylinder engine with 8 horsepower. Today's EcoBoost has 178 horsepower," Whalen says, while keeping in character.
Whalen grew up in Michigan. He has played historical parts at The Henry Ford museum, including Orville Wright. The Wright brothers, Orville and Wilbur, are credited with building the world's first successful airplane.
Whalen's fellow actor O'Donnell is from California and is new to Ford's historical theater.
Whalen estimates about 25 to 40 other actors auditioned for the job. The actors had to read a two-paragraph script, then answer questions such as: How would you respond if people ask product questions?
Says Whalen: "We direct them to a product specialist."


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NxStage Home Hemodialysis Patient Awareness Tour Kicks Off January 29th
Jan 28, 2013, 08:31 ET
LAWRENCE, Mass., Jan. 28, 2013 /PRNewswire/ -- NxStage® Medical, Inc. (Nasdaq: NXTM), a leading manufacturer of innovative dialysis products, announced today that NxStage patient advocate Jim Smith, 64, of Indianola, Washington is beginning the first NxStage Home Hemodialysis Patient Awareness Tour of 2013 with a 4-week journey starting January 29th.
(Logo: http://photos.prnewswire.com/prnh/20110503/MM94799LOGO )
The Tour is designed to increase patient awareness of home hemodialysis and consists of Smith, along with his wife and care partner, Claire, making 16 scheduled stops at dialysis centers in Georgia and South Carolina. Smith will speak with dialysis patients about the benefits of more frequent home hemodialysis and perform demonstrations with his NxStage System One™.
Smith's journey with NxStage began in 2007. Discouraged with how in-center treatment 3 times a week impeded his work, travel, and lifestyle, Smith researched other dialysis options and learned about home therapy with the System One. After completing training with his care partner, he began dialyzing at home with the System One.
"I understand the challenges of life on dialysis firsthand, and look forward to meeting with other patients to share my experiences with more frequent home hemodialysis with the System One. My goal is to help raise awareness and access to this life-changing therapy," said Smith.
"We're really excited to partner with Jim to increase patient awareness of our therapy," said Jeff Burbank, NxStage founder and CEO. "This inspiring tour is a great venue to reach patients and share experiences as well as to demonstrate how therapy with our innovative and portable System One can help transform the quality of life for patients needing dialysis."
For more information on Jim's journey with NxStage and the System One, visit, www.nxstage.com/homehemodialysis/patientstories/jim.
Smith receives a modest stipend from NxStage as well as reimbursement for travel expenses directly associated with these stops.
About the NxStage System One
The NxStage System One is the first and only truly portable hemodialysis system cleared for home use by the U.S. Food & Drug Administration (FDA). Its simplicity and revolutionary size (just over a foot tall) provide convenient use in patients' homes and give patients the freedom to travel with their therapy. Unlike conventional hemodialysis systems, the System One requires no special infrastructure to operate. Under the guidance of their physician, patients can use the NxStage System One, with their trained partners, where, how and when it best meets their needs, at home or on the road.
About NxStage Medical Inc.
NxStage is a medical device company, headquartered in Lawrence, MA, USA, which develops, manufactures, and markets innovative systems for the treatment of end-stage renal disease (ESRD), and acute kidney failure. The System One home hemodialysis device developed by NxStage is the only FDA approved portable hemodialysis machine cleared for home use. For more information on NxStage, or NxStage products, visit, http://www.nxstage.com.
Forward-Looking Statements
This release contains "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this release that are not clearly historical in nature are forward-looking, and the words "anticipate," "believe," "expect," "estimate," "plan," and similar expressions are generally intended to identify forward-looking statements. Actual results may differ materially from those indicated by these forward-looking statements as a result of various important factors including those that are discussed in NxStage's filings with the Securities and Exchange Commission, including the Quarterly Report on Form 10-Q for the quarter ended September 30, 2012. NxStage is under no obligation to (and expressly disclaims any such obligation to) update or alter its forward-looking statements, whether as a result of new information, future events or otherwise.
Kristen K. Sheppard, Esq.
Vice President, Investor Relations and Corporate Counsel
NxStage Medical Inc.
SOURCE NxStage Medical, Inc.


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Modulation of Monocyte Activation by Atorvastatin in HIV Infection
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT01263938
Recruitment Status : Completed
First Posted : December 21, 2010
Last Update Posted : December 12, 2017
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Activated monocytes play a key role in the pathogenesis of HIV-associated neurocognitive disorders (HAND). Individuals with HAND have expanded populations of activated monocytes. These monocytes are thought to emigrate into the CNS, where they produce neurotoxic proinflammatory factors, and also carry virus into the CNS. Statins are cholesterol lowering drugs with pleiotropic immunomodulatory / anti-inflammatory properties that are currently being explored for immunomodulation of T cell activation in several diseases, in addition to their established role to treat hyperlipidemia and atherosclerosis. The investigators in vitro data suggests that these drugs can downregulate monocyte activation patterns seen in HIV infection. No in vivo studies have yet been carried out to assess the effects of statins on the pro-inflammatory monocyte population in chronic HIV disease. This will be a pilot study of whether statin treatment will reduce the inflammatory monocyte phenotype and downregulate the inflammatory cytokines that have been linked to neuropathogenesis in HIV infection. If so, they may have potential as adjunctive therapy in HIV-associated neurological disease. The investigators propose to:
- Determine the effect of Atorvastatin on peripheral blood monocyte populations in a 12-week pilot study in chronically HIV-infected people on HAART therapy.
- Determine the relationship between changes in monocyte phenotype following Atorvastatin treatment, and soluble markers of activation/inflammation linked to neuropathogenesis, as well as activation status of T cells.
|Condition or disease
|HIV Dementia
|Drug: Atorvastatin
|Phase 4
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|5 participants
|Intervention Model:
|Single Group Assignment
|None (Open Label)
|Primary Purpose:
|Official Title:
|Pilot Study to Evaluate Effects of Atorvastatin on Monocyte Activation in HAART-treated HIV Infected Individuals
|Study Start Date :
|September 2011
|Actual Primary Completion Date :
|October 2017
|Actual Study Completion Date :
|October 2017
Drug: Atorvastatin
For subjects on PI-based HAART therapy: 10mg/day X 2weeks followed by 20mg/day.
For subjects on non PI-based HAART therapy: 20mg/day X 2weeks followed by 40mg/day.
Other Name: Lipitor
- Effect of statins on peripheral blood monocytes [ Time Frame: Subjects enrolled in the study following the screening visit will be assessed for the primary outcome measures at T=0 (drug intervention begins); T=2wks; T=6wks; T=12wks (intervention ends); T=16wks (study ends) ]
Primary outcome measures include:
- Surface marker analyses of monocyte phenotype
- Plasma levels of soluble inflammatory mediators
- Effect of statins on T cell markers [ Time Frame: Subjects enrolled in the study following the screening visit will be assessed for the secondary outcome measures at T=0 (drug intervention begins); T=2wks; T=6wks; T=12wks (intervention ends); T=16wks (study ends) ]
Secondary outcome measures include:
- T cell surface markers
- expanded plasma cytokine profile
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years and older (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Chronic HIV-1 infected individuals presently on HAART with no change in drug combination for at least 3 months at time of enrollment
- Plasma viral load <200 copies / ml for at least 6 months prior to enrollment in the study
- CD4 T cell count more than 350/ul
- Willingness to use a method of contraception during the study period
- Willingness to have blood drawn
- If female, willingness to undergo pregnancy testing on a monthly basis and are not breastfeeding
- Ability to understand and willingness to sign the informed consent
- hs-CRP levels above the upper limit of normal (>3mg/L)
Exclusion Criteria:
- Concomitant use of fibric acid derivatives or other lipid lowering agents including patients on statins and Ezetimibe
- Use of any anti-inflammatory drugs (OTC or prescription) on a daily basis
- Pregnancy or breast feeding
- Active drug use or alcohol abuse/dependence, which in the opinion of the investigators will interfere with the patient's ability to participate in the study
- Allergy or hypersensitivity to statins or any of its components
- History of myositis or rhabdomyolysis with use of any statins
- Patients who are on concurrent immunomodulatory agents, including systemic corticosteroids will be ineligible for 3 months after completion of therapy with the immunomodulating agents
- History of inflammatory muscle disease such as poly or dermatomyositis
- Serious intercurrent illness requiring systemic treatment and/or hospitalization within 30 days of entry
- Evidence of active opportunistic infections requiring treatment or neoplasms that require chemotherapy during the study period
- Creatine phosphokinase elevations (CPK) greater than 3 times the upper limit of normal
- Known active liver disease or AST/ALT greater than 2x the upper limit of normal
- Renal insufficiency, indicated by serum creatinine 2 mg/dl
- Absolute neutrophil count (ANC) 1000/mm3, hemoglobin < 10.0 g/dL for males and <9 g/dL for females, platelet count 100,000/mm
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01263938
|United States, Pennsylvania
|University of Pennsylvania School of Medicine
|Philadelphia, Pennsylvania, United States, 19104
|Principal Investigator:
|Ronald G Collman, MD
|University of Pennsylvania
|Responsible Party:
|University of Pennsylvania
|ClinicalTrials.gov Identifier:
|NCT01263938 History of Changes
|Other Study ID Numbers:
IRB Protocol #: 812196
P30AI045008 ( U.S. NIH Grant/Contract )
|First Posted:
|December 21, 2010 Key Record Dates
|Last Update Posted:
|December 12, 2017
|Last Verified:
|December 2017
Keywords provided by University of Pennsylvania:
Additional relevant MeSH terms:
HIV Infections
AIDS Dementia Complex
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurocognitive Disorders
Mental Disorders
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
Atorvastatin Calcium
Anticholesteremic Agents
Hypolipidemic Agents
Molecular Mechanisms of Pharmacological Action
Lipid Regulating Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Enzyme Inhibitors


text:
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Frank Horwill
- These articles were first published many year's ago and whilst some are as relevant today as they were when new, many are now mostly of historical interest as modern research and coaching methods have superseded them.
Running Over 40
By Frank Horwill
It can safely be said, fifty years ago, that a person who continued to run or took up running after the age of forty, was considered to be, at least, a little eccentric by the average person. Even in the sport, veteran runners were given grudging respect. I can recall, at the age of seventeen, battling it out over a 6 mile cross-country course through Ruislip Woods, with a stoutish man of fifty. Afterwards, I looked at him in the dressing-room with some awe and finally said, "Why are you still running?" He replied, "This is part of my preparation for the Poly Marathon." From that reply I assumed that all marathoners were virtually ancient marathoners. This fact was reinforced by the numbers on the starting line for that race - hardly ever more than fifty.
The late Dr George Sheehan was to alter this thinking, "Running is part of ecology and preserving the good things. There is no such thing as growing old; you're either growing up or stagnant. You can be old at 20." He wrote numerous letters to the local and national Press stating that running isn't necessarily kid's stuff. Eventually, he became a columnist in 1970, in a new journal called Runner's World, where he preached the theme: run for your life.
Another pioneer was David H. R. Pain, a San Diego lawyer, who, in 1968 started the US Masters track and field championships. Within thirty years this move altered the lives of millions world-wide. It caused runners to look forward to their 40th birthday, and their 50th, and their 60th!
Middle-aged runners stand in sharp contrast to a gluttonous, lazy and obese society. They do not possess the fanaticism of the abstemious, nor the excesses of the hedonist. They follow Dr. Johnson's view of things, "He who lives medically lives miserably." They like a pint or two., some even like a cigar or two (medical experts say that the pipe is the least harmful, then comes the cigar. The killer is the cigarette.). On the other hand, they listen to Emerson's dictate, "The best wealth is health."
Now, there is something special about the veteran runner and Runner's World were the first to discover it. They were and are in the habit of sending out questionnaires to their readers. At first just 100; now 1,000. Their usual return was 60 per cent. But, when they surveyed 100 veteran runners, they got an 80 per cent return. That fact alone speaks well for their enthusiasm. And the returns revealed some potent facts. Age has dimmed their basic speed, but increased their staying power to the point where they are often better than much, younger runners.
Unfortunately, age makes one more susceptible to injuries but not as much as those who start running at an early age. A runner who has 25 years' experience has developed certain muscle groups, while the novice has not. However, when injured, they take longer to heal. Recent research suggests that the main cause of injury is training too many days in succession. If a vet is in the habit of training six days consecutively and gets more than one injury per hundred hours of running (16 weeks of 1 hour per day), it is time to consider training three days consecutively with the fourth off.
Unlike many of their younger counterparts, vets have stabilised their occupational and financial position, and can roam the world competing in all types of races. Age has taken from the vets, but time also has provided compensations.
The surveys also reveal that there is no "typical" runner. Most race above track distances, where speeds and competitive opportunities suit them best, but Dave Moorcroft at 40, broke the world's vet mile record outdoors with a 4:02 reading (he alleges that creatine monohydrate played a big part), while Eamonn Coghlan became the first vet to run a sub 4-minute mile indoors. Notice anything special about these two? Well, they started running at 14 and never stopped. World vet records favour this group on the track. But this is not always the case with longer distances. Take, for example, Jack Foster of New Zealand. He started running at 32. He became an Olympian at 40! At age 33 he ran a 2:27:50 marathon, and at 38, 2:12:17. At 41, he ran 2:11:18.
He did not like the word "training": he called it running. He broke the 20-mile world record (1:39:14) when 39. He averaged 10 miles a day, seven days a week. His longest run lasted 2½ hours. His shortest session was 3x1 mile in 4:40 on a horse track with 3 minutes jog recovery. He won eight marathons.
If you like running, you will like it more if, for your age, you get better at it. A regular pattern of training is the key to greater enjoyment. Running every other day for not less than 35 minutes paves the way for greater things. After 12 weeks of this, you are ready for one run of 70 minutes each week. After 12 weeks of that, the world is your oyster.