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Special Populations
This web page is archived for historical purposes and is no longer being updated. Newer content is available at www.cdc.gov/std/treatment
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Pregnant Women
Intrauterine or perinatally transmitted STDs can have severely debilitating effects on pregnant women, their partners, and their fetuses. All pregnant women and their sex partners should be asked about STDs, counseled about the possibility of perinatal infections, and provided access to treatment, if needed.
Recommended Screening Tests
- All pregnant women in the United States should be screened for HIV infection as early in pregnancy as possible (77). Screening should be conducted after the woman is notified that she will be screened for HIV as part of the routine panel of prenatal tests, unless she declines (i.e., opt-out screening). For women who decline HIV testing, providers should address their objections, and when appropriate, continue to encourage testing strongly. Women who decline testing because they have had a previous negative HIV test should be informed of the importance of retesting during each pregnancy. Testing pregnant women and treating those who are infected are vital not only to maintain the health of the patient, but to reduce perinatal transmission of HIV through available antiretroviral and obstetrical interventions. Retesting in the third trimester (preferably before 36 weeks' gestation) is recommended for women at high risk for acquiring HIV infection (e.g., women who use illicit drugs, have STDs during pregnancy, have multiple sex partners during pregnancy, live in areas with high HIV prevalence, or have HIV-infected partners). Rapid HIV screening should be performed on any woman in labor who has an undocumented HIV status unless she declines. If a rapid HIV test result is positive in these women, antiretroviral prophylaxis should be administered without waiting for the results of the confirmatory test (78).
- A serologic test for syphilis should be performed on all pregnant women at the first prenatal visit (79). In populations in which the amount of prenatal care delivered is not optimal, rapid plasma reagin (RPR) card test screening (and treatment, if that test is reactive) should be performed at the time that a pregnancy is confirmed. Women who are at high risk for syphilis, live in areas of high syphilis morbidity, or are previously untested should be screened again early in the third trimester (at approximately 28 weeks' gestation) and at delivery. Some states require all women to be screened at delivery. Infants should not be discharged from the hospital unless the syphilis serologic status of the mother has been determined at least one time during pregnancy and preferably again at delivery. Any woman who delivers a stillborn infant should be tested for syphilis.
- All pregnant women should be routinely tested for hepatitis B surface antigen (HBsAg) during an early prenatal visit (i.e., a visit during the first trimester), even if they have been previously vaccinated or tested (80). Women who were not screened prenatally, those who engage in behaviors that put them at high risk for infection (e.g., having had more than one sex partner in the previous 6 months, evaluation or treatment for an STD, recent or current injection-drug use, and an HBsAg-positive sex partner) and those with clinical hepatitis should be retested at the time of admission to the hospital for delivery. Pregnant women at risk for HBV infection also should be vaccinated. To avoid misinterpreting a transient positive HBsAg result during the 21 days after vaccination, HBsAg testing should be performed before vaccine administration. All laboratories that conduct HBsAg tests should use an FDA-cleared HBsAg test and perform testing according to the manufacturer's labeling, including testing of initially reactive specimens with a licensed neutralizing confirmatory test. When pregnant women are tested for HBsAg at the time of admission for delivery, shortened testing protocols can be used, and initially reactive results should prompt expedited administration of immunoprophylaxis to infants (80).
- All pregnant women should be routinely screened for Chlamydia trachomatis (see Chlamydia Infections, Diagnostic Considerations) during the first prenatal visit (81). Women aged ≤25 years and those at increased risk for chlamydia (e.g., women who have a new or more than one sex partner) also should be retested during the third trimester to prevent maternal postnatal complications and chlamydial infection in the infant. Women found to have chlamydial infection during the first trimester should be retested within approximately 3–6 months, preferably in the third trimester. Screening during the first trimester might prevent the adverse effects of chlamydia during pregnancy, but supportive evidence for such screening is lacking.
- All pregnant women at risk for gonorrhea or living in an area in which the prevalence of Neisseria gonorrhoeae is high should be screened at the first prenatal visit for N. gonorrhoeae (82). Women aged <25 years are at highest risk for gonorrhea infection. Other risk factors for gonorrhea include a previous gonorrhea infection, other STDs, new or multiple sex partners, inconsistent condom use, commercial sex work, and drug use. Pregnant women found to have gonococcal infection during the first trimester should be retested within approximately 3–6 months, preferably in the third trimester. Uninfected pregnant women who remain at high risk for gonococcal infection also should be retested during the third trimester.
- All pregnant women at high risk for hepatitis C infection should be screened for hepatitis C antibodies (see Hepatitis C, Diagnostic Considerations) at the first prenatal visit. Women at high risk include those with a history of injection-drug use and those with a history of blood transfusion or organ transplantion before 1992.
- Pregnant women should undergo a Papanicolau (Pap) test at the same frequency as nonpregnant women, although recommendations for their management differ (83,84).
Other Tests
- Evidence does not support routine testing for bacterial vaginosis (BV) in pregnancy. For asymptomatic pregnant women at high risk for preterm delivery, evidence is insufficient to assess the balance of benefits and harms of screening for BV (85). Symptomatic women should be evaluated and treated (see Bacterial Vaginosis).
- Evidence does not support routine screening for Trichomonas vaginalis in asymptomatic pregnant women. Women who report symptoms should be evaluated and treated appropriately (see Trichomonas).
- Evidence does not support routine HSV-2 serologic screening among previously undiagnosed women during pregnancy.
Other Concerns
- Pregnant women who are HBsAg positive should be reported to the local or state health department to ensure that they are entered into a case-management system and that timely and appropriate prophylaxis is provided for their infants. Information concerning the pregnant woman's HBsAg status should be provided to the hospital in which delivery is planned and to the health-care provider who will care for the newborn. In addition, household and sex contacts of women who are HBsAg positive should be vaccinated.
- Women who are HBsAg positive should be provided with, or referred for, appropriate counseling and medical management. Pregnant women who are HBsAg positive should receive information regarding hepatitis B that addresses:
- modes of transmission;
- perinatal concerns (e.g., breastfeeding is not contraindicated);
- prevention of HBV transmission, including the importance of postexposure prophylaxis for the newborn infant and hepatitis B vaccination for household contacts and sex partners; and
- evaluation for and treatment of chronic HBV infection.
- No treatment is available for pregnant women infected with hepatitis C virus (HCV). However, all women with HCV infection should receive appropriate counseling and supportive care as needed (see Hepatitis C, Prevention). No vaccine is available to prevent HCV transmission.
- In the absence of lesions during the third trimester, routine serial cultures for herpes simplex virus (HSV) are not indicated for women who have a history of recurrent genital herpes. Prophylactic cesarean delivery is not indicated for women who do not have active genital lesions at the time of delivery.
- The presence of genital warts is not an indication for cesarean delivery.
For a more detailed discussion of STD testing and treatment among pregnant women, refer to the following references: Prenatal screening for HIV: A Review of the evidence for the U.S. Preventive Services Task Force (86); Revised Recommendations for HIV Testing of Adults, Adolescents, and Pregnant Women in Health-Care Setting (77); Guidelines for Perinatal Care (87); Rapid HIV Antibody Testing During Labor and Delivery for Women of Unknown HIV Status: A Practical Guide and Model Protocol (88); Viral Hepatitis in Pregnancy (89); Hepatitis B Virus: A Comprehensive Strategy for Eliminating Transmission in the United States — Recommendations of the Immunization Practices Advisory Committee (ACIP) (4); Screening for Chlamydial Infection: U.S. Preventive Services Task Force Recommendation Statement (81); Canadian guidelines on sexually transmitted infections (90); USPSTF recommendations for STI screening (91); and Screening for Bacterial Vaginosis in Pregnancy to Prevent Preterm Delivery: U.S. Preventive Services Task Force Recommendation Statement (85).
Recommendations to screen pregnant women for STDs are based on disease severity and sequelae, prevalence in the population, costs, medicolegal considerations (e.g., state laws), and other factors. The screening recommendations in this report are generally broader (i.e., if followed, more women will be screened for more STDs than would by following other screening recommendations) and are also consistent with other CDC guidelines.
In the United States, prevalence rates of many sexually acquired infections are highest among adolescents (92,93). For example, the reported rates of chlamydia and gonorrhea are highest among females aged 15–19 years, and many persons acquire HPV infection during their adolescent years.
Persons who initiate sex early in adolescence are at higher risk for STDs, along with persons residing in detention facilities, attending STD clinics, young men having sex with men (YMSM), and youth who use injection drugs. Factors contributing to this increased risk during adolescence include having multiple sexual partners concurrently, having sequential sexual partnerships of limited duration, failing to use barrier protection consistently and correctly, having increased biologic susceptibility to infection, and experiencing multiple obstacles to accessing health care (92).
All 50 states and the District of Columbia explicitly allow minors to consent for their own health services for STDs. No state requires parental consent for STD care or requires that providers notify parents that an adolescent minor has received STD services, except in limited or unusual circumstances.
Protecting confidentiality for such care, particularly for adolescents enrolled in private health insurance plans, presents multiple problems. After a claim has been reported, many states mandate that health plans provide a written statement to a beneficiary indicating the benefits and charges covered or not covered by the health plan (i.e., explanation of benefit [EOB]). In addition, federal laws obligate notices to beneficiaries when claims are denied, including alerting consumers who need to pay for care until the allowable deductible is reached. For STD detection- and treatment-related care, an EOB or medical bill that is received by a parent might disclose services provided and list any laboratory tests performed. This type of mandated notification breeches confidentiality, and at a minimum, could prompt parents and guardians to question the costs and reasons for service provision.
Despite the high rates of infections documented in the adolescent population, providers frequently fail to inquire about sexual behaviors, assess STD risks, provide risk reduction counseling, and ultimately, fail to screen for asymptomatic infections during clinical encounters. Sexual health discussions should be appropriate for the patient's developmental level and should be aimed at identifying risk behaviors (e.g., unprotected oral, anal, or vaginal sex and drug-use behaviors). Careful, nonjudgmental, and thorough counseling is particularly vital for adolescents who might not feel comfortable acknowledging their engagement in behaviors that place them at high risk for STDs.
Screening Recommendations
Routine laboratory screening for common STDs is indicated for sexually active adolescents. The following screening recommendations summarize published federal agency and medical professional organizations' clinical guidelines for sexually active adolescents:
- Routine screening for C. trachomatis of all sexually active females aged ≤25 years is recommended annually (81).Evidence is insufficient to recommend routine screening for C. trachomatis in sexually active young men based on feasibility, efficacy, and cost-effectiveness. However, screening of sexually active young men should be considered in clinical settings associated with high prevalence of chlamydia (e.g., adolescent clinics, correctional facilities, and STD clinics) (81,94).
- Routine screening for N. gonorrhoeae in all sexually active women at risk for infection is recommended annually (82). Women aged <25 years are at highest risk for gonorrhea infection. Other risk factors that place women at increased risk include a previous gonorrhea infection, the presence of other STDs, new or multiple sex partners, inconsistent condom use, commercial sex work, and drug use.
- HIV screening should be discussed with all adolescents and encouraged for those who are sexually active and those who use injection drugs (77,95).
- The routine screening of adolescents who are asymptomatic for certain STDs (e.g., syphilis, trichomoniasis, BV, HSV, HPV, HAV, and HBV) is not recommended. However, YMSM and pregnant adolescent females might require more thorough evaluation.
- Guidelines from USPSTF and ACOG recommend that cervical cancer screening begin at age 21 years (96,97), a recommendation based on the low incidence of cervical cancer and limited utility of screening for younger adolescents (98). However, the American Cancer Society (ACS) recommends that women start cervical screening with Pap tests 3 years after initiating sexual activity, but by no later than age 21 years (99).
Primary Prevention Recommendations
Primary prevention and anticipatory guidance to recognize symptoms and behaviors associated with STDs are strategies that can be incorporated into any or all types of health-care visits. The following recommendations for primary prevention of STDs (i.e., vaccination and counseling) are based on published federal agency and medical professional organizations' clinical guidelines for sexually active adolescents:
- The HPV vaccine, either Cervarix or Gardasil, is recommended for 11 and 12 year-old females. The vaccine series can be started at 9 years of age. Catch-up vaccination is recommended for females aged 13–26 years who have not yet received or completed the vaccine series (16). The quadrivalent (Gardasil) HPV vaccine can also be used in males and females aged 9–26 years to prevent genital warts (17).
- The HBV vaccination series is recommended for all adolescents. Adolescents who have not previously received hepatitis B vaccine should be vaccinated routinely at any age with an appropriate dose and schedule (3,4).
- The HAV vaccination series for children and adolescents aged 2–18 years should be offered in areas with existing hepatitis A vaccination programs. In areas without existing hepatitis A vaccination programs, catch-up vaccination of unvaccinated children aged 2–18 years can be considered (2).
- Information regarding HIV infection, testing, transmission, and implications of infection should be regarded as an essential component of the anticipatory guidance provided to all adolescents as part of health care (77).
- Health-care providers who care for children and adolescents should integrate sexuality education into clinical practice. Providers should counsel adolescents about the sexual behaviors that are associated with risk for acquiring STDs and should educate patients using evidence-based prevention strategies, all of which include a discussion about abstinence and other risk-reduction behaviors (e.g., consistent and correct condom use). USPSTF recommends high-intensity behavioral counseling to prevent STIs* for all sexually active adolescents (6).
Management of children who have STDs requires close cooperation between clinicians, laboratorians, and child-protection authorities. Official investigations, when indicated, should be initiated promptly. Certain diseases (e.g., gonorrhea, syphilis, and chlamydia), if acquired after the neonatal period, are virtually 100% indicative of sexual contact. For other diseases (e.g., HPV infections and vaginitis), the association with sexual contact is not as clear (see Sexual Assault and STDs).
Persons in Correctional Facilities
Multiple studies have demonstrated that persons entering correctional facilities have high rates of STDs (including HIV) and viral hepatitis, especially those aged ≤35 years (93). Incarcerated persons are more likely to have low socioeconomic status, live in urban areas, and be ethnic and racial minorities. Risk behaviors for contracting STDs (e.g., having unprotected sex; having multiple sexual partners; using drugs and alcohol; and engaging in commercial, survival [prostitution to earn money for food, shelter, or drugs], or coerced sex) are common among incarcerated populations. Before incarceration, many have had limited access to medical care, especially to community-based clinical prevention services.
Although no comprehensive national guidelines regarding STD care and management have been developed for correctional populations, the utility of expanded STD services in correctional settings has been reported (100). Capacity to provide STD care also varies by type of correctional facility. For example, local juvenile detention facilities and jails are short-term facilities (often housing entrants for ≤1 year) where up to half of all entrants are released back to the community within 48 hours of arrest, thereby complicating efforts to provide comprehensive STD services. These services are likely more conducive to prisons and state juvenile confinement facilities, which are long-term, secure facilities where entrants are held for a longer period of time.
Most institutions, especially those for adults, do not routinely screen for STDs. Diagnostic testing of inmates with symptoms indicative of an STD is the more common practice in juvenile detention and jail facilities. However, screening for asymptomatic infections facilitates the identification and treatment of persons with otherwise undetected infections, which not only eliminates complications for the individual, but reduces the prevalence of infection among detainees who are released back into the local community.
Females in juvenile detention facilities and young women ≤35 years of age have been reported to have high rates of chlamydia (101) and gonorrhea (93). Syphilis seroprevalence rates, which can indicate previous infection, are considerably higher among adult men and women than in adolescents, consistent with the overall national syphilis trends (102).
Chlamydia and Gonorrhea Screening
Universal screening of adolescent females for chlamydia and gonorrhea should be conducted at intake in juvenile detention or jail facilities. Universal screening of adult females should be conducted at intake among adult females up to 35 years of age (or on the basis of local institutional prevalence data).
Syphilis Screening
Universal screening should be conducted on the basis of the local area and institutional prevalence of early (primary, secondary, and early latent) infectious syphilis.
Subgroups of MSM are at high risk for HIV infection and other viral and bacterial STDs. The frequency of unsafe sexual practices and the reported rates of bacterial STDs and incident HIV infection declined substantially in MSM from the 1980s through the mid-1990s. However, since that time, increased rates of early syphilis (primary, secondary, or early latent), gonorrhea, and chlamydial infection and higher rates of unsafe sexual behaviors have been documented among MSM in the United States and virtually all industrialized countries (103,104). The effect of these behavioral changes on HIV transmission has not been ascertained, but preliminary data suggest that the incidence of HIV infection is increasing among MSM in some urban centers, particularly among MSM from racial and ethnic minority groups (105) and among those who use nonprescription drugs during sex, particularly methamphetamine and volatile nitrites (also known as "poppers"). These adverse trends likely reflect the 1) changing attitudes concerning HIV infection that have accompanied advances in HIV therapy, resulting in improved quality of life and survival for HIV-infected persons; 2) changing patterns of substance abuse; 3) demographic shifts in MSM populations; and 4) changes in sex partner networks resulting from new venues for partner acquisition (e.g., the internet). Increases in bacterial STDs are not necessarily accompanied by increases in HIV incidence; for example, oral sex may permit efficient spread of bacterial STDs but not HIV, as does serosorting (preferential selection of sex partners of the same serostatus) among HIV-infected MSM (106,107).
Clinicians should assess the STD-related risks for all male patients, including a routine inquiry about the sex of sex partners. MSM, including those with HIV infection, should routinely undergo nonjudgmental STD/HIV risk assessment and client-centered prevention counseling to reduce the likelihood of acquiring or transmitting HIV or other STDs. Clinicians should be familiar with the local community resources available to assist MSM at high risk in facilitating behavioral change and to enable the conduct of partner notification activities. Clinicians also should routinely ask sexually active MSM about symptoms consistent with common STDs, including urethral discharge, dysuria, genital and perianal ulcers, regional lymphadenopathy, skin rash, and anorectal symptoms consistent with proctitis, including discharge and pain on defecation or during anal intercourse. Clinicians should perform appropriate diagnostic testing on all symptomatic patients.
Routine laboratory screening for common STDs is indicated for all sexually active MSM. The following screening tests should be performed at least annually for sexually active MSM:
- HIV serology, if HIV negative or not tested within the previous year;
- syphilis serology, with a confirmatory testing to establish whether persons with reactive serologies have incident untreated syphilis, have partially treated syphilis, or are manifesting a slow serologic response to appropriate prior therapy;
- a test for urethral infection with N. gonorrhoeae and C. trachomatis in men who have had insertive intercourse† during the preceding year; testing of the urine using nucleic acid amplification testing (NAAT) is the preferred approach;
- a test for rectal infection§ with N. gonorrhoeae and C. trachomatis in men who have had receptive anal intercourse† during the preceding year (NAAT of a rectal swab is the preferred approach); and
- a test for pharyngeal infection§ with N. gonorrhoeae in men who have had receptive oral intercourse† during the preceding year (NAAT is the preferred approach). Testing for C. trachomatis pharyngeal infection is not recommended.
Evaluation for HSV-2 infection with type-specific serologic tests also can be considered if infection status is unknown; knowledge of HSV-2 serostatus might be helpful in identifying persons with previously undiagnosed genital tract infection.
Because of the increased incidence of anal cancer in HIV-infected MSM, screening for anal cytologic abnormalities can be considered; however, evidence is limited concerning the natural history of anal intraepithelial neoplasias, the reliability of screening methods, the safety and response to treatments, and the programmatic support needed for such a screening activity.
More frequent STD screening (i.e., at 3–6-month intervals) is indicated for MSM who have multiple or anonymous partners. In addition, MSM who have sex in conjunction with illicit drug use (particularly methamphetamine use) or whose sex partners participate in these activities should be screened more frequently.
All MSM should be tested for HBsAg to detect HBV infection. Prompt identification of chronic infection with HBV is essential to ensure necessary care and services to prevent transmission to others (108). HBsAg testing should be made available in STD treatment settings. In addition, screening among past or current drug users should include HCV and HBV testing.
Vaccination against hepatitis A and B is recommended for all MSM in whom previous infection or vaccination cannot be documented (2,3). Preimmunization serologic testing might be considered to reduce the cost of vaccinating MSM who are already immune to these infections, but this testing should not delay vaccination. Vaccinating persons who are immune to HAV or HBV infection because of previous infection or vaccination does not increase the risk for vaccine-related adverse events (see Hepatitis B, Prevaccination Antibody Screening). Sexual transmission of hepatitis C virus infection can occur, especially among HIV-infected MSM. Serologic screening for hepatitis C infection is recommended at initial evaluation of newly diagnosed HIV-infected persons. HIV-infected MSM can also acquire HCV after initial screening; therefore, men with new and unexplained increases in alanine aminotransferase (ALT) should be tested for acute HCV infection. To detect acute HCV infection among HIV-infected MSM with high-risk sexual behaviors or concomitant ulcerative STDs, routine HCV testing of HIV-infected MSM should be considered.
Women Who Have Sex with Women
Women who have sex with women (WSW) are a diverse group with variations in sexual identity, sexual behaviors, sexual practices, and risk behaviors. Recent studies indicate that some WSW, particularly adolescents, young women, and women with both male and female partners, might be at increased risk for STDs and HIV as a result of certain reported risk behaviors (109-112). WSW are at risk for acquiring bacterial, viral, and protozoal infections from current and prior partners, both male and female. WSW should not be presumed to be at low or no risk for STDs based on sexual orientation. Effective screening requires that providers and their female clients engage in a comprehensive and open discussion not only about sexual identify, but sexual and behavioral risks.
Few data are available on the risk for STDs transmitted by sex between women, but risk probably varies by the specific STD and sexual practice (e.g., oral-genital sex; vaginal or anal sex using hands, fingers, or penetrative sex items; and oral-anal sex [113,114]). Practices involving digital-vaginal or digital-anal contact, particularly with shared penetrative sex items, present a possible means for transmission of infected cervicovaginal secretions. This possibility is most directly supported by reports of metronidazole-resistant trichomoniasis (115) and genotype-concordant HIV transmitted sexually between women who reported these behaviors (116) and by the high prevalence of BV among monogamous WSW (117).
Transmission of HPV can occur with skin-to-skin or skin-to-mucosa contact, which can occur during sex between women. HPV DNA has been detected through polymerase chain reaction (PCR)-based methods from the cervix, vagina, and vulva in 13%–30% of WSW, and high- and low-grade squamous intraepithelial lesions (SIL) have been detected on Pap tests in WSW who reported no previous sex with men (118). However, most self-identified WSW (53%–99%) report having had sex with men and indicate that they might continue this practice in the future (119). Therefore, routine cervical cancer screening should be offered to all women, regardless of sexual preference or sexual practices, and women should be offered HPV vaccine in accordance with current guidelines.
Limited data demonstrate that HSV-2 genital transmission between female sex partners is probably inefficient but can occur. The relatively frequent practice of orogenital sex among WSW might place them at higher risk for genital infection with herpes simplex virus type 1 (HSV-1), a hypothesis supported by the recognized association between HSV-1 seropositivity and number of female partners among WSW (120).
Although the rate of transmission of C. trachomatis between women remains largely unknown, infection also can be acquired from past or current male partners. Recent data suggest that C. trachomatis infection among WSW might be more common than previously thought (121); transmission of syphilis between female sex partners (likely through oral sex) also has been reported. Therefore, report of same-sex behavior in women should not deter providers from screening these women for STDs, including chlamydia and syphilis, as recommended.
BV is common among women in general and even more so among women with female partners. Sexual behaviors that facilitate the transfer of vaginal fluid and/or bacteria between partners might be involved in the pathogenesis of BV. A recent study demonstrated that female sex partners frequently share identical genital Lactobacillus strains (122). Although BV is common in WSW, routine screening for BV is not recommended, nor is the treatment of partners of women with BV. Encouraging awareness of signs and symptoms of BV in women and encouraging healthy sexual practices (e.g., cleaning shared sex toys between uses) might be helpful.
*STI is the term used by USPSTF to describe the syndromes caused by various pathogens that can be acquired and transmitted through sexual activity.
† Regardless of history of condom use during exposure.
§ Commercially available NAATS are not FDA cleared for these indications, but they can be used by laboratories that have met all regulatory requirements for an off-label procedure.
- Page last reviewed: January 28, 2011 (archived document)
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$57 Million Brancusi Leads Best Christie's Impressionist and Modern Sale in Seven Years
Artsy Editorial
Signed and dated to lower right 'FL 44'. This work has been authenticated by the Comité Léger and will be sold with a certificate of authenticity.
From Lascaux to Brooklyn, Rand, pg. 10 illustrates this work
The Collection of Paul Rand, acquired circa 1960
Working in Paris during the height of Cubism, Fernand Léger's iconic style, with its emphasis on primary colors and rounded, massive forms, has become informally regarded as "Tubism." Even at their most abstract, Léger's subjects are easier to recognize than the rigorous Cubist dissections of Pablo Picasso and Georges Braque, and the accessibility and contemporary subject matter of his works have led many to describe Léger as both populist and a forerunner of Pop Art. Interested in modern innovation, Léger joined the Puteaux Cubists, engaging with Robert Delaunay, Francis Picabia, and Jean Metzinger, among others. His interest in industry and machines was further encouraged by the Italian Futurist painters, and by his military service for France during World War I. While Léger would later revisit more traditional subjects—including the female nude, landscape and still life—these works retained his characteristically bold style.
French, 1881-1955, Argentan, France, based in Paris, France
$57 Million Brancusi Leads Best Christie's Impressionist and Modern Sale in Seven Years
Artsy Editorial
My Highlights from The Salon: Art + Design
Eric Cohler
Calder and his Friends
Artsy Editorial

subset: commoncrawl


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Seattle, WA – Northwest Immigrant Rights Project (NWIRP) today condemned the separation of children from mothers who have been transferred to Washington State and are now being held at the Federal Detention Center in SeaTac.Seattle, WA
Over this past week the Department of Homeland Security (DHS) transferred as many as 120 asylum seekers from Texas to the Federal Detention Center (FDC) in SeaTac, Washington. Initial reports demonstrate the group consists of many women who originally arrived with their children seeking asylum, but were then separated from their children by Border Patrol officials and prosecuted for unlawful entry, a federal misdemeanor. Despite completing their sentences, the mothers remain in federal detention while applying for asylum and separated from their children who are being held at separate government facilities.
NWIRP staff first learned of this development after meeting with two women yesterday, June 6th. The two women arrived at the United States' southern border with their young daughters in mid-May seeking asylum. Both were separated from their children shortly after they were apprehended by Border Patrol. The two women were charged with the misdemeanor crime of unlawful entry and sentenced to time served. But instead of being returned to their children, who are now held at different government facilities, the two women were transferred to Washington State while they proceed forward with the asylum process. The two women reported that approximately 60 other women in similar circumstances are currently being held in the same section of the Federal Detention Center. Moreover, there are now reports of an additional group of 60 asylum seekers being held in a separate section of the FDC at SeaTac. NWIRP staff is actively working to reach as many of them as possible to provide legal assistance.
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No position group has bedeviled the
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over the last decade quite like the signal callers under center. This fall, the team's fate would seems to rest in the inexperienced hands of redshirt freshman Tanner Morgan. Should he turn out to be competent, it will have been a long and strange road, riddled with the unfulfilled potential of countless Gopher quarterbacks.
Today we turn the spotlight to:
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Streveler had a stellar high school career at Marian Central Catholic High School in Illinois, leading his team to identical 11-1 records and conference championships as both a junior and a senior. Both teams also advanced to the state quarterfinals. As a junior, Streveler passed for 2,456 yards and 26 touchdowns, in addition to rushing for 970 yards and 17 touchdowns. He was named first-team All-State as a senior, when he finished the season 172-of-250 (68.8%) for 2,662 passing yards and 26 touchdowns, to go along with 1,276 rushing yards and 22 touchdowns.As a Gopher


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Agreement reached to clean up North End property in ManchesterBy PAT GROSSMITH
New Hampshire Union Leader
October 30. 2013 10:56PM
MANCHESTER — A man the city has been after for five years to clean up his North End property ran into a no-nonsense Superior Court judge Wednesday and the hearing ended with an agreement to clean up the property within 30 days.
Nadir Atiya of 703 Maple St. initially didn't bother to appear for the 9 a.m. hearing before Judge Philip Mangones in Hillsborough County Superior Court, Northern District. Instead, his 64-year-old father, Salahdien Atiya, showed up on his behalf.
The judge asked him where his son was, after explaining the father would have to file the proper paperwork in order to represent him.
"He's home cleaning up the property," Salahdien Atiya told him.
"Well, he should be here," Mangones said, adding he was sure the city was happy to hear he was cleaning it up.
"He's mentally handicapped. That's very well established," the father said of his son.
Assistant city solicitor Peter R. Chiesa told the judge that Nadir Atiya sent his father to court hearings in the past instead of appearing as he should. While he was found incompetent by a judge in Circuit Court in one case, the same judge realized that was not the case after Atiya testified in an unrelated court matter, according to neighbors and city officials.
Salahdien Atiya informed the judge he was "an international law adviser" but conceded he was not a lawyer or member of the New Hampshire Bar Association. He asked the judge to set another hearing date and he would make sure his son appeared.
The judge ultimately told him to call his son on his cell phone and tell him he had until 10:30 a.m. to appear in court. If he did not show up, Mangones said he would enter an order against him by default.
Salahdien Atiya left the courthouse and returned just before 10:30 a.m. with his son, who was dressed in a dark blue, ripped jumpsuit. Nadir Atiya proceeded to the defense table, where he poured himself and his father each a glass of water. He took a long drink of water and then leaned back in the chair, his hands on top of his head with his fingers interlocked, as if he didn't have a care in the world.
When the judge entered the courtroom and the proceeding began, Mangones asked Nadir Atiya if he could hear him, since he had indicated to the court clerk that he couldn't hear her. "Hi," Nadir Atiya said. "But can you hear me?" the judge asked again. "Yes," he said.
"I suggest you take these proceedings seriously," the judge admonished him. But when the judge asked him if the sheriff's department had served him with court papers concerning the hearing, Nadir Atiya said he hadn't, that he never saw a sheriff. "What papers?" he asked. Chiesa told the judge he could see the documents in the file in front of Atiya on the defense table. Atiya then told the judge he did receive them.
But, he asked, why they put "Junior" after his name. "Is this some kind of practical joke?" he asked.
"We are here for a legal proceeding not some farce on the street corner," Mangones told him. "If you would like to go to jail for contempt of court, I will be happy to put you in jail."
That seemed to get Nadir Atiya's attention, and he agreed to a proposed order by the city that requires him to clean up the property of tires, auto parts, firewood and other clutter within 30 days and to provide the court with proof that it is done.
Under the agreement, if the property is not cleaned up in 30 days, the city will be allowed to take care of it and Nadir Atiya will have to pay the cost of abating the nuisance. The city will be able to go after him for payment similar to the way unpaid taxes are collected. Mangones explained it meant the city can chase him for the costs.
"Well, they have been chasing me for a long time," Nadir Atiya said.
He quickly left the courthouse without commenting but his father told a New Hampshire Union Leader reporter that they had started cleaning up the property two weeks ago, about the time Nadir Atiya was served the court papers.
"Everything will be cleaned up," said the father who also lives at the Maple Street residence. "I am very sure it will be fine." About a half-dozen neighbors, along with Mayor Ted Gatsas, attended the hearing.
For years, the city has hauled Atiya into Circuit Court for violating city ordinances with the junk kept on the property.
Sometimes the property gets picked up a bit, but then the junk begins to accumulate again, according to James Tierney, the city's Code Enforcement Officer.


text:
HOLLYWOOD, April 27 (UPI) -- A hearing was set for Lindsay Lohan, who allegedly failed to respond to a suit by a woman who said the actress hit her with her car in Hollywood, TMZ reported.
Nubia Del Carmen Preza sued Lohan after the "Mean Girls" star allegedly nicked her with her Maserati while exiting a parking garage in her West Hollywood neighborhood in September 2010, TMZ said.
Preza, a nanny, was pushing a baby stroller at the time and said Lohan narrowly missed hitting the child.
The nanny's attorney filed legal documents wanting answers from Lohan about the alleged accident, but she never responded, TMZ reported.
A hearing has been set for May 8 for a judge to determine whether Lohan should face fines for failing to answer the questions, the celebrity gossip website said.
Lohan is scheduled to be in rehab on the date of the hearing.


text:
TRITTON Titanfall Kunai Stereo Headset for PC and Xbox 360
The best way to hear Sarah say, ""Standby for Titanfall"
- Compatible with Xbox 360 and PC
- Adjust your chat and game volume separately and on-the-fly
- Use them with your smartphone or iPod, too
If you don't have the option not to play multiplayer, you'd better be able to hear (and talk to) the rest of the players on your team. Communication is key. Just ask Leeroy Jenkins. Dangit. Now we're craving chicken.
If you haven't been playing with a headset, you don't know what you've literally been missing. The Tritton Kunai can transform your gaming world for not a lot of dough. Tritton's Kunai (from the same people who bring you Mad Catz) shines in FPS situations where hearing footsteps could make the difference in restarting the mission, but it doesn't stop there. It gives you the ability to adjust your chat and game volume separately and on-the-fly on the Xbox 360 with an in-line audio controller. Plus, you can pop the microphone off and use the headphones to listen to your iPod.
Product Specifications
- Tritton Titanfall Kunai Gaming Headset in Titanfall color scheme
- Compatible with Xbox 360 and PC
- Officially-licensed Titanfall merchandise
- Supports online chat
- Adjust your chat and game volume separately and on-the-fly (Xbox 360 only) with an in-line audio controller (also has mic mute slider)
- Microphone is removable
- Supra-aural (on-ear) cups swivel to provide a comfortable around-the-neck resting position
- Speaker Diameter: 40mm
- Neodymium magnet
- Frequency Response: 20Hz–20kHz
- Total Harmonic Distortion (THD): <1%
- Signal-to-Noise Ratio (SNR): 106 dB/V
- Resistance: 16 ohms
- USB-powered
- Standard 3.5mm plug lets you use them with your smartphone, iPod, or anything with a headphone output
- Adjustable headrail extends an extra 1.25" on either side to accommodate a wide range of head sizes
- Dimensions: Xbox cable length 14 ft., 3.5mm cable length 3 ft.
- Includes stereo headset with 3.5mm connector cable, in-line audio controller, removable & flexible microphone, RCA cable adapter with pass-through, analog audio adapter, 2 Xbox Live communication cables, and Titanfall decals


text:
General's Highway baseball program aims to teach children necessary skills to play the game of baseball while imparting a strong sense of sportsmanship, and teamwork. Our coaches encouragement of player effort provides for greater enjoyment by the player and ultimately leads to better skilled and better motivated players.
New Privacy Policy


text:
CLINTON, N.Y. (AP) — Hillary Rodham Clinton on Friday derided the partial government shutdown, saying dysfunction and gridlock are emblematic of too many people in politics choosing "scorched earth over common ground."
The former senator and secretary of state said during a speech at Hamilton College in upstate New York that it was difficult to recall a time when "politicians were willing to risk so much damage to the country to pursue their own agendas."
Clinton described some of the lessons she learned during her time in the Senate and at the State Department, contrasting it with the budget battle engulfing Congress and the White House and a looming deadline to raise the nation's debt limit.
"Today, too many in our politics choose scorched earth over common ground. Many of our public debates are happening in what I like to call an evidence-free zone, where ideology trumps data and common sense," she said. "That is a recipe for paralysis, not progress."
Recalling shutdowns during the mid-1990s, Clinton noted that her husband worked with then-House Speaker Newt Gingrich to find a way to reopen the government. Neither side got everything it wanted, she said, but it led to a balanced budget and economic growth.
Clinton said the stalemate could have repercussions around the globe, noting that the shutdown had forced President Barack Obama to cancel his trip to Asia for meetings with world leaders. "Russia is there. China is there. We're not there," Clinton said, arguing that it could affect the way the U.S. is perceived around the globe.
Polls show Clinton would be the leading contender for the White House in 2016 if she decides to seek the presidency again. The Hamilton address, before 5,800 people jammed into the college's field house, offered glimpses of a possible campaign.
Clinton received loud applause at several points during her speech and question-and-answer session and shook hands with dozens of students and others along a blue partition after the event. Some stretched out their smart phones to take a picture of the former first lady.
Hamilton's president, Joan Hinde Stewart, said the college's speaker series had brought to campus former President Bill Clinton, prime ministers, secretaries of state and other leaders. "Never yet a future president, but there's a first time for everything," Stewart said to cheers.
Clinton avoided any talk of another White House campaign, but she spoke of the need to promote trade around the globe and to help young people find jobs.
"We need to be thinking together again, not fighting the same old stale arguments," Clinton said. "I worked with Republicans and Democrats. I worked with business leaders and labor leaders, anybody with a good idea. So let's think about how we're going to spur growth again."
Describing lessons she learned as the nation's top diplomat, Clinton said that after a decade of war and financial crisis, "the United States remains the indispensable nation."
"For me this isn't even a question. We have to lead. I hear all the talk about America needs to pull back and not be so active. That's not the world I've seen," she said.
Clinton said that after traveling the world, "my faith in our country is deeper. Our optimism about our future is strong. But we're not going to get there by accident or hoping for it. We're really going to have to work hard, we're going to have to make this country work for all of us again."
Concluding her remarks, Clinton urged the audience, "Let's take this country that has given so much to people like us, the greatest force for peace and progress that the world has ever known and resolve we are going to pull together."
She added: "We are going to get out of the evidence-free zone. We're going to start looking at the facts. We're going to roll up our sleeves. We're going to solve our problems together. We're going to build a kind of future that our children and our grandchildren deserve."
Follow Ken Thomas on Twitter: http://twitter.com/AP_Ken_Thomas


text:
Pharmacokinetic Interactions Between Telaprevir and Un-boosted Atazanavir
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT01818856
Recruitment Status : Completed
First Posted : March 27, 2013
Last Update Posted : April 22, 2013
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
|Condition or disease
|Hepatitis C, Chronic HIV Infection
|Drug: Ritonavir withdrawal, atazanavir 200 mg/12h Drug: Telaprevir interactions
|Phase 1
- Primary Outcome Measures: evaluate the changes in the plasma pharmacokinetic parameters (Cmax, Cmin, AUC, t 1/2, and Cl) of Telaprevir (TVR) administered at 750 mg/8h together with un-boosted Atazanavir (200 mg/12h), taking as reference the pharmacokinetic parameters observed when TVR is administered with Atazanavir/ritonavir (300/100 mg/day)
- To assess the changes in the plasma pharmacokinetic parameters of Atazanavir administered as 200 mg/12h with respect to its administration as 300/100 mg/day when administered together with TVR (750 mg/8h or 1125 mh/12h).
Method: open labelled clinical trial with a planned duration of 24 weeks in which 14 HIV/Hepatitis C virus genotype 1 patients under treatment with pegylated α-interferon, Ribavirin and Telaprevir will be enrolled. A 24 hours pharmacokinetic profile will be obtained after a supervised drug intake while taking TVR and ATV/rtv. Afterwards, the patients will take un-boosted ATV 200 mg bid for 7 - 10 days. Subsequently, a new pharmacokinetic profile will be obtained.
|Study Type :
|Interventional (Clinical Trial)
|Estimated Enrollment :
|14 participants
|Intervention Model:
|Single Group Assignment
|None (Open Label)
|Primary Purpose:
|Official Title:
|Pharmacokinetic Interactions Between Telaprevir and Un-boosted Atazanavir in HIV/HCV-co-infected Patients Under Treatment for Genotype 1 Chronic Hepatitis C.
|Study Start Date :
|December 2012
|Actual Primary Completion Date :
|April 2013
|Actual Study Completion Date :
|April 2013
Experimental: Telaprevir interactions
Telaprevir 750 mg/8h or 1125 mg/12h (+ pegIFN alfa and ribavirin) plus Atazanavir/ritonavir 300/100 mg/24. Pharmacokinetic profile on day 0.
Intervention: Ritonavir will be withdrawn and the atazanavir dose increased to 200 mg/12h for days 1 to 7. On day 8: a morning dose of Telaprevir (750 mg or 1125 mg) plus Atazanavir 200 mg. Pharmacokinetic profile for 12 hours
Drug: Ritonavir withdrawal, atazanavir 200 mg/12h
Other Names:
Drug: Telaprevir interactions
Other Names:
- Changes in pharmacokinetic parameters of TVR [ Time Frame: 7 - 10 days ]The Telaprevir peak concentrations (Cmax), trough levels (Cmin) at 8 or 12 hours, the areas under the curves over the dosing interval (AUC0-τ), and half-life during the elimination phase (t½ β) will be compared between days 0 and 7 as geometric mean ratios (GMRs) and their 90% CIs using day 0 values as reference. The differences in pharmacokinetic parameters between the regimens will be considered significant when the interval between low and high 90% CI did not include the value 1.0.
- Changes in pharmacokinetic parameters of ATV [ Time Frame: 7 - 10 days ]The Atazanavir peak concentrations (Cmax), trough levels (Cmin) at 12 or 24 hours, the areas under the curves over the dosing interval (AUC0-τ), and half-life during the elimination phase (t½ β) will be summarized as geometric means (GM) and will be compared between days 0 and 7 as geometric mean ratios (GMRs) and their 90% CIs using day 0 values as reference. The differences in pharmacokinetic parameters between the regimens will be considered significant when the interval between low and high 90% CI did not include the value 1.0.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years to 65 Years (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Patients over 18 years old co-infected with HIV and genotype 1 HCV under treatment with pegylated α-interferon, Ribavirin and Telaprevir according to the recommendations of the Spanish Agency of Medicines and Health Products.
- Informed consent of the patient.
Exclusion Criteria:
- The usual exclusion criteria in clinical practice to start the treatment with these drugs (pegylated α-interferon, Ribavirin, Telaprevir and atazanavir) according to the Spanish and international recommendations (Spanish Agency of Medicines and Health Products,European Association for the Study of the Liver Clinical Practice Guidelines: management of hepatitis C virus infection. J Hepatol. 2011. Consensus Document of Gesida/Spanish Plan on Aids regarding the antiretroviral treatment in adults infected with the human immunodeficiency virus [Updated January 2012]).
- Concomitant use of drugs or medicinal products that could alter the pharmacokinetics of TVR or ATV.
- Medical records suggesting malabsorption or presence of diarrhea (>3 depositions/day) that could interfere with the absorption of the studied drugs.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01818856
|Hospital Universitario Virgen del Rocio
|Seville, Spain, 41013
|Principal Investigator:
|Luis F Lopez-Cortes, MD, PhD.
|Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla. Spain.
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|Luis F. Lopez-Cortes, MD, PhD, Hospitales Universitarios Virgen del Rocío
|ClinicalTrials.gov Identifier:
|NCT01818856 History of Changes
|Other Study ID Numbers:
2012-002515-25 ( EudraCT Number )
|First Posted:
|March 27, 2013 Key Record Dates
|Last Update Posted:
|April 22, 2013
|Last Verified:
|April 2013
Keywords provided by Luis F. Lopez-Cortes, Hospitales Universitarios Virgen del Rocío:
Chronic hepatitis C
Drug interaction
Additional relevant MeSH terms:
Hepatitis A
Hepatitis C
HIV Infections
Hepatitis C, Chronic
Liver Diseases
Digestive System Diseases
Hepatitis, Viral, Human
Virus Diseases
Enterovirus Infections
Picornaviridae Infections
RNA Virus Infections
Flaviviridae Infections
Lentivirus Infections
Retroviridae Infections
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
Hepatitis, Chronic
Atazanavir Sulfate
HIV Protease Inhibitors
Protease Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Anti-HIV Agents
Anti-Retroviral Agents
Antiviral Agents
Anti-Infective Agents


text:
The Sixers strolled into San Antonio this weekend seemingly getting ready to play a team that was ripe for the taking. The Spurs were playing their third game in as many nights, were without future Hall of Famer Tim Duncan, as coach Greg Popovich decided to give him a rest and the Sixers were coming off a solid effort in a sound victory over Boston on Friday.
But Tony Parker and company had enough legs, and bountiful smarts, to easily do away with the Sixers by 93-76. Let's just run down, individually, what is going on with the Sixers right now.
Andre Iguodala: He had to sit out Sunday's game after the pain in his left knee was too great. The official term for the injury is patella tendonitis. Iguodala has looked much slower in the past few games, perhaps due to the knee. The scary thing is last year he missed 15 games, mostly due to tendonitis in his OTHER knee. Click here for an injury update after today's practice.
Jrue Holiday: Coach Doug Collins has continuously told him he needs to score. Holiday did just that, going for 10 points in the first quarter against the Spurs, then didn't score again the rest of the game. Need more consistency from him.
Evan Turner: If you graded a player on body language, Turner would be carrying a failing grade. He is most happy with the ball in his hands, scoring, dealing and rebounding. His rebounding has been down of late and Collins says that is the best way for him to get the ball in his hands.
Spencer Hawes: He is starting to round into shape after missing most of the season with a strained Achilles', only he doesn't realize it. Sure his game is going to show rust - jump shots coming up short, balls getting bobbled - but Hawes can't let that play on his mind. His outbursts on the court over his own play truly hurt him. Collins can't spend time trying to calm his young center down during every game.
Elton Brand: He is showing signs of playing the way he was a year ago, when he led the team in scoring and rebounding. Sure his game has fallen off from his prime, maybe even from a year ago, but he is the only player on this team who will fight his way through troubles.
Nikola Vucevic: Not sure if the rookie backup center has hit the rookie wall so hard that he's been knocked unconscious or if he just can't adjust to Collins' demands right now. He looks absolutely lost out on the court right now. Collins has seemed to have lost all confidence in him.
Jodie Meeks: He is what he is - sometimes. On a team that is struggling to reach 85 in the scoring column right now it's kind of understanding why Collins is giving him a lot of minutes. Obviously, when this team is playing well, Meeks should be a 10-15 minute guy, looking to spread defenses by hitting open jumpers.
Thaddeus Young: Probably the Sixers' most consistent player this season, Young appears to be exhausted. Going against bigger players every night has taken its toll, and Collins said Friday that Young is down to below 210 pounds, almost 10 pounds lighter than where he would like him to be. Imagine being 210 and battling 250-pound monsters each night. He is simply worn down.
Lou Williams: If there is a player who can be defined by "As he goes, so go the Sixers," it's Williams. When he is on, the team offensively flows so much better. Problem here is other teams are now running out after Williams as soon as he crosses halfcourt, taking away his ability to get to the basket or get open for jump shots.
Sam Young: If Iguodala's injury proves to be something that keeps him out for some time, we could be seeing a lot of Young. His physicality really sticks out on a team that is sorely lacking it.
Right now the one thing that was so positive about this team early in the season - its youth - is hurting it. There is too much moping, too much complaining, too much "me-first" going on right now. They won 20 of their first 29 games by playing team basketball and hounding defense. All of the sudden, in many cases, it's become about the individuals.
And now their Atlantic Division lead, once seemingly secure, is gone. With Boston's win at Charlotte Monday night, the teams are tied atop the division at 27-22. With 17 games remaining, their position remains very fragile. And if their recent play continues, so does a playoff spot.


text:
Daisies and lace
Along Highway 68/80 as it approaches Hopkinsville from the east, the ditches are full of white wildflowers. I don't think they were planted by the State Highway Department. I believe the long, cool, damp spring this year made it easy for wildflower seeds to sprout and get established.
These are Queen Anne' lace, oxeye daisies, and another locally common wildflower that puts on clusters of tiny daisy-like flowers. I think they might be a type of fleabane (possibly Philadelphia fleabane), but I'm not sure. The USDA Plants database returns 244 results for "fleabane", and I'm too lazy tonight for earnest research.


text: Had shuttle pass this year. Palm Springs line. Never had a problem getting the shuttle to head down each day. Always a shuttle ready to go as soon as I was outside the hotel. The only issue I had was Saturday late afternoon I was heading back and 4 shuttles rolled in and all went on break one after another. There was only 4-5 of us waiting but that was jacked up. The VMT guy felt bad after the third shuttle went on break so he called in a van to take us into Palm Springs. Adam, our driver was really great. Even waited for some of us to run into hotel change and take us back. So all in all the shuttle experience was positive and I'll do it again next year.


text:
March 9, 2010
20 people you should know
PodCamp Nashville was a massive success this past weekend. The blog posts and tweets have been so positive.
While the mandate of Podcamp is that everyone is equal and everyone is a rock star, there are some rock stars I want to highlight here.
These stars are the people who spent their Tuesday evenings meeting for the past few months. They spent endless hours tweaking documents, writing copy, designing ads, brainstorming marketing ideas, contacting sponsors, scheduling sessions, confirming location logistics, managing budget, and much, much more. They are the PodCamp Nashvile 2010 crew.
Scott Justice
Andrew Duthie
Julie Moore
Lucas Hendrickson
Dani Heileman
Erin Cubert
Brad Blackman
Brett Henley
Julia Corrigan
John Ellis
Stephen Yeargin
Darren Crawford
Jason Beck
May Hwen
Courtenay Rogers
Jessica Murray
Chuck Bryant
Les Gebhardt
Kate O'Neill
Thomas Vaughn
I've created a Twitter list of the PCN10 Crew you can follow to see what these incredible people are tweeting. I'd advise following it for a wealth of genius and humor.
Without these people there wouldn't have been a PodCamp 2010. Next time you see them please say thank you, buy them a drink, give them a hug!
And thank YOU if you attended or sponsored PCN10.
Fan us on Facebook for PodCamp 2011. We'll need your help, so consider becoming a rock star now.


text:
Amazon's Flow has been available on iOS since November of last year and has finally made its way onto Android. Not unlike Google Goggles, Flow let's you scan products like DVDs, books, video games, and more, and shows product details, pricing, and a buy button (to purchase from Amazon, of course). The scanning is done by simply pointing your phone's camera at the product, or scanning the product's bar code. The Android version of Flow also scans QR codes, a feature currently lacking in the iOS version but expected to come in the future.
Something Flow does on both platforms, however, is provide a live augmented reality view for certain products which displays things like movie trailers and other media using its image recognition technology. Simply point the camera at a DVD cover, for example, and instantly see an overlay popup with movie info and video previews. I guess you can technically call this augmented reality, but it's not quite as fancy as other AR apps since you're just looking at a closeup of a single object and seeing related information… something just as easily done by scanning a bar code.
Head on past the break for screenshots and a Play Store download link.
The above image was a scan of a DVD cover for a Harry Potter movie. Note the video preview under the buy button.
This image shows a scan of the cover of an Adele album, with a song preview available.
Flow is available now in the Google Play store.
source: techcrunch


text: Block 7 of the Alphabet Quilt is Toys. Measuring 28.5" x 39", this fat quarter friendly applique block features American Jane with her flag & wagon, a toy soldier at his post, a drum & a wooden paddle with its rubber ball - all in celebration of a parade. From the waving flags to the beating drums & marching soldiers, everyone loves a parade! This applique Toys block makes a wonderful wall hanging or pillow in addition to being the seventh of nine blocks needed for the whole Alphabet Quilt. Designed by Sandy Klop


text:
1 - 18 of 18 Comments Last updated Aug 21, 2017
"Sounding off for the citizens"
Since: Oct 10
#1 Oct 11, 2010
The Iowa Outdoor Recreation Trust Fund Amendment, also known as Measure 1, will appear on the November 2, 2010 ballot in the state of Iowa as a legislatively-referred constitutional amendment.
If the measure is approved by a simple majority of Iowa voters, the next time the Iowa Legislature approves a sales tax increase, the measure would allow 3/8ths of one cent to be used in support of the Natural Resources and Outdoor Recreation Trust Fund. This would establish permanent revenue for natural resources and outdoor recreational programs in the state. It has been reported that this would generate about $150 million a year. T
If the measure is enacted, about $150 million of the estimated tax pot would be spent on outdoor recreation and natural resources, which includes:
Natural resources: 23 percent would be allocated to state parks, state forests, state preserves, wildlife areas and other.
Soil conservation and water protection: 20 percent would be used for soil conservation and watershed protection
Watershed protection: 14 percent would be used to help preserve watersheds
Resource Enhancement and Protection Program: 13 percent of the revenue would be used for natural, cultural, and recreational resources parks, trails, museums, and roadside beautification.
Local conservation partnership: 13 percent would be handed out to local communities for areas pertaining to outdoor and recreation
Trails: 10 percent would go to outdoor trails for recreational use.
Lake restoration: 7 percent would go to public lake restoration around the state.
How will you vote on November 2nd?
#2 Oct 18, 2010
The radio ad running that supports this measure - is a lie. It says twice "without raising taxes" but the measure itself says it can only go into effect WHEN SALES TAX IS RAISED. So how they can get away with claiming it is "without raising taxes" is beyond me. Someone should take that ad off the air - it is an outright lie.
#3 Oct 23, 2010
Its just another money grab ,dont be foolish, VOTE NO !
#4 Oct 23, 2010
We are taxed enough the way it is. How do we like socialism now! they get enough revenue from licenses,waterfowl stamps and the like. I can't save for my kid's college now with all the taxes. Enough is Enough!!!!!!
#5 Oct 24, 2010
Don't miss out on more "Honey Creeks." Investors call it "Money Creek." The DNR rips Iowans off more than any other department.
#6 Oct 25, 2010
I mostly agree with all that has bee posted here except that the Measure will not raise taxes in the sense that a new tax will me enacted or that sales tax will increase. It only means that if and when our sales tax increases then they could claim 3/8 of 1 cent. That is peanuts when you really think about it. But I do agree that enough tax increases. They raise our property tax rate, the income taxe rate is adjusted every year, gas taxes are on the increase. Where does it all end.
Honey (money) Creek is where it is, because of one reason. Patty Judge. A longtime resident of Monroe County. Although Rathbun Lake is in Appanoose County it is just a hop, skip, and jump from Albia her hometown. It is there because of her and until I am convinced otherwise that's my answer. She is against economical development in areas where it makes sense and Honey Creek does not make sense. She trashed the Earth Park on Red Rock which made more sense than Honey Creek. It is closer to Des Moines and a short distance off of a major arterial highway between Des Moines and Ottumwa.
Okay now I am really off topic.
#7 Oct 29, 2010
Boy folks to like to rant about taxes, don't they? I suppose it's healthy to have something to vent about, but it gets really unhealthy when it turns into endless (and yes quite hypocritical) government bashing. What do you want to do away with - state parks and soil conservation? Roads and schools and public safety? Public health and Medicare and Social Security? And please don't come back with the same tired old line that the government wastes our money - given what we've seen in the financial and related sectors these past few years, I'm perfectly comfortable with our Iowa civil servants spending a bit of my money on priorities we as a state decide together.
Come on folks, pretty much all of us pay less in taxes now than 30 years ago, and if all the ranters claims were true, and we were continuously being taxed more and more (as the Enough! crowd screams), well then it wouldn't take long before we had no money at all, would it?
Final point: I agree the radio ad causing so much consternation is misleading, but it's not incorrect. It won't raise taxes, it will "take effect" by becoming the law of the land when voters pass it. It will only actually fund important conservation and recreation opportunities in Iowa, however, if/when the sales tax is increased, someday.
For the sake of my kids and a healthy and vibrant Home Place Iowa, I look forward to that day, and will gladly part with 3/8ths of a percent of every dollar I spend to put towards cleaner water, more productive soils, diverse landscapes, and outdoor recreational activities for kids that spend more hours than any kids in history on couches and in front of screens.
Happy ranting!
#8 Nov 1, 2010
Did I dream this or was it a few years ago that the State of Iowa raided the pockets of the parks and recreation of the so called excess money in their accounts and incorporated the money into the State funds.
That's simular to the Federal Government raiding the social security savings, spending it all to try and avoid a recession. Something our wonderful elected officials do for us?
#9 Jan 21, 2011
Enough about taxes already
#10 Jan 28, 2011
Leave us out of this.
#11 Feb 1, 2011
Even though this "ISSUE" has already been considered. Citizens of "IOWA" didn't fall off the apple cart yesterday, although may times from past events it appears, distorted teachings have permiated "IOWA SCHOOL SYSTEMS". Just look at "WHOM" Iowa helped carrie to the White House, then look long at the elected leaders tied to "ITS" strings, then consider, IS IT "time to clean house"
"You cann't kill stupid !" "BUT" "You can "VOTE" IT OUT !"
#12 Feb 9, 2011
#13 May 29, 2011
Vladivostok, Russia
#16 Oct 16, 2011
lol :)))) so so so nice)))IOWA SCHOOL SYSTEMS". Just look at "WHOM" Iowa helped carrie to the White House, then look long at the elected leaders tied to))) ITS strings, then consider, IS IT "time to clean house. Million player winning strong)))
#17 Oct 19, 2011
Odd that there's many more proponents on HeyIowa. com than on here. Maybe it's the age demographic difference.
#18 Oct 19, 2011
What do they intend to do with the money they already give to natural resources? I'm for tax cuts not increases dummies.
#23 Mar 16, 2014
I just voted no.
#26 Aug 21, 2017
This is a really good cause. However, specific funding and how
the funding is provided, really, really, really does not belong in the constitution. Constitutions are meant to provide the general framework for how the state is run. Amendments and
"Propositions " is what has got California in the mess it is in.
I would encourage passing a law providing for funding but not an amendment!!! Not the purpose of a constitution.
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Double the size
Dyn creates California-style office environmentBy DAVE SOLOMON
New Hampshire Union Leader
August 31. 2013 3:01AM
MANCHESTER -- Let's say you're an up-and-coming software engineer at Dyn, trying to work out a solution for a client like Twitter or CNBC.
You and your manager at one of the state's fastest growing tech firms could talk it over across a desk in the traditionally stilted office environment, or you could bounce ideas off each other while playing Ping-Pong in the game room, knocking in a few golf balls at the indoor putting green, sipping cappuccino in the Dyn Cafe Annex or spotting each other for a few bench presses in the gym.
All of those options have been made possible by a $1 million-plus expansion that doubled the space Dyn occupies at 150 Dow St. in the Manchester Millyard, from 30,000 to 60,000 square feet.
There are plenty of new work stations for Dyn's growing number of employees, not to mention hanging gardens, original murals and a small movie theater.
In a project that began in January, the company completely refurbished the first floor of the building in which it occupied the second floor, creating a two-level, integrated work space to accommodate expected growth to 300 employees by the end of this year.
The company, which manages network services, Internet traffic, email delivery and email reporting for more than 4 million business and personal clients, now has 235 employees with posted openings for another 80, according to Media Relations Manager Adam Coughlin.
Stirring creativity
Prior to the expansion, Dyn had about 200 employees crowded into a space built for 160 to 170. That second-floor space had already been featured in local media and the trade press for amenities such as arcade games, a rock climbing wall, a deck overlooking the Merrimack River and a private restaurant.
The new space doubles down on that philosophy, with white masonry painted to look like red brick, new entrances from Dow or Commercial streets and a solarium leading to a new cafe.
A conference center with space for 300 and a theater with seating for 50 are designed for internal training, product launches, community events and the occasional movie night.
It's all designed to help Dyn attract the best and the brightest in the competitive employment market for high-end technical talent, while creating an environment in which they can do their most creative work, Coughlin said.
"Some of our best ideas come to us on the golf course or in the movie theater," he said while trying his hand on the putting green. "We're trying to replicate those experiences to get the creative juices flowing."
The putting green in particular helps push egos aside. "It's a very humbling game," Coughlin said, as his custom-made Dyn golf ball rolled slightly to the right of the hole in an area highlighted by floor-to-ceiling murals of famous New Hampshire golf courses, created by students from the New Hampshire Institute of Art.
A recruiting tool
"We see not only the Dyn culture, but our space as a recruiting tool," said Paul Mailhot, vice president of business operations and clerk of the works for the expansion, which exceeded the company's $1 million estimate, although he declined to say by how much.
The amenities at the Dyn international headquarters are unusual in New Hampshire, but not that unique in an industry that requires constant innovation and a workforce not wedded to a time clock.
"This environment we've created is very typical in California, but not in the Northeast," said Mailhot, currently chairman of the state's High Tech Council. "As more tech companies locate and expand in New Hampshire, this type of environment will become more common."
Mailhot, who worked with tech firms in Marin County and San Francisco, said the space planning and design for the expansion was influenced by several locations he's worked in or visited, including the Google campus in Boulder, Colo.
As the company continues to grow at a torrid pace, the refurbished Dow Street mill building offers even more room for expansion.
"We're certainly not done yet," Mailhot said. "We're eyeing another 40,000 to 50,000 square feet in the same building. Our intent is to stay here. We enjoy this building and the relationship we have with the landlord and other tenants."
It isn't all fun and games. The original plan for the recently completed expansion called for a playground slide to take employees from one level to the other, but that idea was sacrificed in the interest of more cubicles.
"We're still planning on putting in a slide with a future expansion," Coughlin said.
Technology Featured Business Manchester Photo Feature Business Headlines


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Having a baby is an expensive time, so, for your total convenience, we at Everything Baby are delighted to offer you use of our 'Club' facility in order to make frequent smaller payments, taking away the worry of a large lump sum payment. All we ask is that the full amount is paid on collection from store or at least 28 days prior to the delivery date of your order. Please refer to our Club Terms &amamp; Conditions for further information.
Call Us +353 (47) 30829
Address:Fleming's Department Store, Church Street, Monaghan,Co. Monaghan,
© 2015 Flemings Department Store - Everything Baby. All Rights Reserved.


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Star Citizen reaches $5 million with 17 hours to go
Roberts Space Industries has had to add another stretch goal to its already stretched crowd-funding campaign after combined totals from its Star Citizen campaigns topped $5 million.
The Kickstarter page has brought in over $1.7 million while the primary, self-hosted program has acquired more than $3.3 million.
As a result, Star Citizen can now boast a record for greatest total raised by a crowd-funded game.
The project initially asked for $2 million and has been adding stretch goals every few days as the numbers continued to soar.
The latest stretch goal is $5.5 million, which will unlock the Bengal carrier, add professional motion capture to military sim component Squadron 42, and reward every backer with 1,000 credits and an exclusive Record Breaker skin.
At $6 million, Roberts Space Industries promises 100 star systems, a full orchestral score, and a free copy of the first Squadron 42 mission disk, a 16 mission affair called Behind Enemy Lines, for all backers.
The last two milestones, $4.5 and $5 million, unlocked a new system, 70 systems and 50 missions at launch, hardcore flight sim controller support, playable destroyers, a Vanduul trading post base, a tablet application, increased community updates, town hall meetings with Chris Roberts and celebrity voice acting with "at least one returning favorite" for Squadron 42.
There are just 17 hours left on the clock; check out the end of campaign livestream.
Star Citizen is expected on PC in late 2014. Perhaps its time to revisit the sim's rousing trailer?


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Friday night's meeting between Diamond Ranch and Bishop Amat is Fox Sports West's high school football game of the week.
It'll be televised at 7 p.m. Check out the Fox broadcast team.
Diamond Ranch is 1-3 but don't let that fool you. The combined record of the three teams to which it has lost is 12-1. The team it beat 21-0 is Colony, a two-time defending CIF champ. Head coach Roddy Layton has put together a brutal nonleague schedule each of his three seasons at the helm.
After missing the playoffs the last three seasons, Bishop Amat (3-1) seems to have the program headed back in the right direction.


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Policy: X.E.1x2
Issued: July 17, 1989
Owner: University Comptroller
Latest Review: March 8, 2000
1.0 Purpose
This policy relates to the lending of a University collection to an outside borrower.
2.0 Policy [Top]
2.1 General Considerations
A department should decide what objects will be loaned. The value, rarity and condition may influence the decision to lend. If an object is on loan to the department, then the owner's permission should be obtained before another loan is made. A donor's restrictions may prevent the lending of those items.
Another consideration is to whom loans will be made. Frequently loans are made only to other educational or non-profit organizations. In this way the loan activity is not interpreted to be a commercial venture.
Authority to approve loans resides with the department chair, although this authority may be delegated.
2.2 Care of Objects
The lending department should ensure that the objects on loan will receive proper care. An inspection of the facilities may be necessary to evaluate the physical conditions and security at the borrowing institution. A loan agreement should specifically state the care that the loaned objects are to receive.
Requirements for transportation, unpacking and repacking should be indicated to the borrower, and the loan agreement should specify who is responsible for these accounts.
The duration of the loan should be stated in the loan agreement. It is the department's responsibility to periodically check that the items are being used for the stated purpose and that insurance valuations are current. Indefinite loan periods are not recommended. When the loan period is completed, the lending department should reclaim its property promptly.
2.3 Insurance
The borrower must provide insurance satisfactory to the department or reimburse the department for the cost of its own coverage.
If the borrower is to provide insurance, the department should request a copy of the policy to confirm that adequate coverage has been obtained. Cancellation or changes in coverage must be conveyed to the department immediately. The loan agreement should state that failure of the borrower to have in effect the agreed upon insurance will not release the borrower from liability for loss or damage.
Insurance valuations can be difficult to determine. Some objects may be irreplaceable or have no readily ascertainable market value. If during negotiations, the department and borrower cannot agree on insurance valuations, it may not be prudent to enter into a loan.
For additional information on insurance valuations and coverage, contact the Office of Risk Management.
See also Policy VII.H.1, "Insurance Coverage."
2.4 Income
The University does not lend collections as a means of generating revenue. However, an organization may desire to compensate the University for the use of a collection. In such situations, the department receiving the request should contact the University Comptroller before establishing an amount.
2.5 Agreement
The agreement related to a loan under this policy is a contract. Therefore, the execution of the agreement must be handled in accordance with University policies governing contracts. See also Policy VII.R.1, "Contracts," for additional information.
3.0 Definitions [Top]
A University collection is defined as any group of objects or works controlled by a University department.
4.0 References [Top]
5.0 Approvals and Revisions [Top]
Previous version in effect from 7/17/89 to 3/8/00 available in policy archive.


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JEROMEĀŚ On a cold snowy night, Hillsdale musician Patrick Martin is a bit nervous. Although heÆs played the room before, Martin, home for winter breakĀfrom the Berklee College of Music in Boston, is trying some new songs along with some more complicated ones.
For a moment he wishes his bandmates from back in Boston were there to reassure him. Martin admits that playing close to home is different because there is no one there to bounce ideas off of.
ōItÆs harder because if IÆm unsure about something, they help. I get a lot of support from the band,ö Martin said.
Martin launches into the material and all the nerves are gone.
ōWhen I started out playing, I used to get nervous. But after playing a song or two I calm down,ö Martin said.
The music production and engineering major is playing a gig at the Deck Down Under in Jerome. ItÆs a room that Martin says is one of his favorites to play in the area.
ōItÆs just a really cool atmosphere,ö Martin said, adding that the partons in the restaurant are always up for a chat after heÆs done.
A fresh seafood restaurant, the Deck Down Under has been hosting live acoustic music during the dinner hours for a little more than a year now and Martin is one of the mainstays, when heÆs home.
ōWe love his style and love what he is about. Anytime he is back from school we definitely make it a point to have him back at least once,ö said owner Janine Serafin. ōHe definitely brings in customers that come out to see him.ö
After having live bands play on SaturdayÆs, Serafin decided that an acoustic offering would better suit the vibe of the restaurant.
ōWe were kind of scaring away some of our dinner crowd,ö Serafin said, adding that the softer music is a better fit. ōItÆs a nice atmosphere for people to come in and enjoy a nice meal on Saturday night.ö
Serafin said that the acoustic offerings have been a success, having paired it with a DJ and karaoke on Friday nights.
For Martin, getting a chance to play at one of his favorite local venues is a nice break from his school work, but says that he is looking forward to seeing what his band, Parasail, has in its future.
ōIÆm sure every band is excited about where they see themselves going, but our band is pretty exciting. The song-writing potential the band has is pretty good,ö Martin said.
An alternative-rock outfit, Parasail consists of Martin and three of his fellow Berklee students. The band is currently working on some music while preparing to start playing some gigs in Boston. Only a sophomore, Martin says he and his band are in no hurry to just throw together an album.
ōWe can use that time to really get our craft down,ö Martin said. ōThereÆs no rush. WeÆre taking the time and making sure we can get 15 tracks down.ö
In the meantime, Martin is focused on working on his major and growing his knowledge of the other side of music.
ōItÆs nice to be on both sides of the booth," he said. "I get a kick out of it."
For more information on future acts playing at The Deck Down Under call 517-900-9213. Martin can be found on Facebook at http://facebook.com/PatrickMartinMusic.
Martin kicks off new year at Deck Down Under


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Reverse Engineering
Long time no post!
Well, check out the article at code.box.sk Newsletter for a Reverse Engineering challenge. The answer is given on the site, but Ill try to crack it on my own, once I get back to Bombay. Ill post my solution here when and if I manage to do it.
Here is the link for the newsletter. See the "Code Challenge: CRACKME Application" on page 25.
If anyone reading is interested and can crack it, post your solution in the comments.


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Around the holidays, the criteria that make for a fine dining establishment get somewhat more narrow: Is it convenient?
Around the holidays, the criteria that make for a fine dining establishment get somewhat more narrow: Is it convenient?
Between bustling among big-box stores and shuttling children and self to parties, lunchtime becomes what you can find wherever you are.
Thankfully, you can get a great meal while you're doing your grocery shopping.
Podesto's Market's deli counter is sandwich shop, Italian mother's kitchen, patisserie and ethnic grocery all in one. Four diners can get four completely different things - a blessing on a family outing.
On a recent weekday, we took a break from a Lincoln Center shopping spree to grab a bite. We were almost overwhelmed at the variety at the counter. But first stop, sandwiches. Get that order in and then spend the wait time perusing the other options.
Between the three of us we got three fairly distinct sandwiches.
Ordering starts by filling out a form at the kiosk in front of the counter. Pick your meat, cheese and condiments, then submit to the cashier.
We tried three permutations: turkey and hot pepper cheese on Dutch crunch; ham and Swiss on local Genova soft bread; and the "Hodge Podge" with cheddar on Genova sourdough. (Hodge Podge is a dollar less than a regular sandwich and includes the extra meat cuttings on hand. For adventure seekers.)
The turkey and hot pepper ($5.99) was a favorite, for the spice of the cheese and the soft texture of the bread. The deli turkey was nice and mild, which let the cheese stand out.
The ham and Swiss ($5.99) was pretty basic, but that's what we wanted. If we'd been able to take it home and toast it, that would've put it over the edge.
Then, the Hodge Podge ($4.99). This was definitely a surprise. Salami and olive loaf were the "meats of the day" and made for an unexpectedly tasty sandwich. We wouldn't have chosen these ourselves (olive loaf isn't even an option on the order form) but the spice of the salami and unique flavor of the olive loaf against the cheddar were a fun combination.
Spanning a whole corner of the store, the deli aims to please every palate. In one section, there were Italian favorites such as lasagna and pastas. We tried a 3-inch square of Spinach and Mushroom Torta ($0.99), which resembled a small quiche. And it kind of tasted like one, too, but without the crust. It was firm textured, standing up to slicing into bite-size pieces. The chunks of spinach and mushroom were diluted with barely any eggy filler, leaving us feeling virtuous and healthy.
The deli salads section was the most mind-boggling. Pasta salad? Check. Potato? Take your pick. Something different? Tuna, seafood, Greek, tomato-mozzarella. We asked about the seafood salad and were offered a taste, which sold us immediately. Imitation crab, celery, green onions and mayo were all chopped up together into a tasty messy mass ($6.99 a pound).
We were far too full for dessert, but the pastry case literally sparkles. Shiny tarts take the spotlight next to cakes and breakfast pastries, all freshly made.
Maybe next time we'll come to fuel up before shopping.
Questions? Comments? Contact LENS Editor Robin Nichols at (209) 546-8274 or firstname.lastname@example.com.