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On July 19, 2011, Apple CEO Tim Cook, during the Q3 Earnings Report, said that he loves competition, but "we want people to invent their own stuff." It appears that his wish was granted.
One of my favorite observations about technology is reaffirmed over and over again: all great things come from the inspired genius of one man. In other words, committees are seldom able to develop new ideas and products because the clutter of competing visions seldom beats the clarity of individual genius.
In the context of Apple, Scott Forstall, from what's been published about him, may have thought that he was carrying on that very same legacy of the idiosyncratic genius of Steve Jobs and, as a result, ruled iOS with an iron hand.
Meanwhile, Apple was about the business of going "thermonuclear" with a patent war against Samsung and (indirectly) Google. I will affirm that before the iPhone came out, smartphones were awful. It was perhaps a driving factor in the development of the iPhone. Below is a chart that Apple has shown depicting how Samsung phones changed after the arrival of the iPhone.
While I am totally sympathetic to Apple as the visionary for the modern touch screen smartphone and respect its rights and patents, I also will admit that it's very hard to seize and maintain control of a compelling new product category that has universal appeal. Very hard.
Apple shows how smartphones came to copy its original vision.
If that were consistently doable in American enterprise, there would only be one car company, one company making TV sets, and only one company making personal computers. So when an incredibly popular idea comes along, like the modern touch screen tablet, one can expect that there will be variations on the original theme. Everyone jumps in, lawsuits happen, but business continues.
I think something remarkable happened while Apple's Mr. Forstall was being very single minded about iOS and Apple's attorneys were suing all the competitors.
Samsung and Google attorneys, managers and very smart engineers all got together. They were spurred by the specter of Apple's litigation and a seeming stagnation in the development of iOS. iOS went from being a great OS for a small 3.5-inch display iPhone to being used on a 9.7-inch tablet, a device many people hope can replace their PCs and Macs.
The problem was that Apple was single minded on keeping not just a single OS for both but a single UI and UX, so while, for example, a single window/single foreground app makes perfect sense on an iPhone, the metaphor is strained to the limit on a full sized iPad. This stagnation was addressed by a David Sobotta in, "Risk Averse: Will iOS Become Apple's Windows XP?" And no doubt, larger iPads are coming, and that will completely break down the metaphor for smart people who, themselves, want to step up their productivity game on tablets.
The customer thirst and competition's appreciation for larger screens and the innovation I've seen with Android 4.x is an evolving phenomenon that Apple has been slow to address. That's probably, we all think, why Tim Cook fired Scott Forstall. Mr. Cook saw that in the fast paced world of innovation and technology from the competition, Apple needed all hands on deck to counter the competitive threats.
Great minds can launch great new things on their own, but over time, when an army of smart people gang up on you, it requires a lot of teamwork, with patent attorney assistance, to maintain a high level of competition in this fast moving technology era. For example, Google is likely deliver a viable Google Glass commercial product later this year. Apple is racing to meet the challenge with its own vision. Can Samsung be far behind?
Tim Cook probably got more of "people inventing their own stuff" than he originally bargained for. As a result, nowadays, observers are expecting Apple, in response, to seriously up its game to a new level. In a frenetic society of A.D.D., blog hits for dollars. social media and instant gratification, the wait is killing us.
Tech News Debris
There was an interesting duo of articles this week on Apple's tablet market share. First, Matt Asay at ReadWrite pondered whether, as Apple's tablet market share drops, profit share must also drop. "As iPad's Market Share Falls, Must Profits Follow?" Incremental improvements to the iPad won't stem that tide. As a result, according to Mr. Asay, Apple needs to be innovative and come out the revolutionary, not evolutionary, products every few years. Even so, despite some wavering, Mr. Asay recognized Apple's business fundamentals, so the article title needs to be taken in the right context.
Later in the week, a crisper analysis was provided by a writer I admire, John Kirk. At Tech.pinions, Mr. Kirk looked more deeply at the thesis that as market share falls, profits must also fall. "Does The Rise Of Android's Market Share Mean The End of Apple's Profits?"
Mr. Kirk noted that "The problem with our obsession with market share is that it rests on two faulty foundations. First, it assumes that every product sold within a category is always just as valuable as another. Second, it assumes that every customer who buys a product is of equal value. These two premises are laughably wrong." What it boils down to is having the right market share that not only has desirable customers but also customers that developers appreciate and can profit from. It's a great article, and I've never seen Mr. Kirk miss the mark.
Why are ISPs invoking data caps? Is it because of network congestion? Are ISPs, like Comcast, who own content creation companies, trying to block competition? Or are they seizing the opportunity to make some extra money to finance their network? It may be a little bit off all these things as various organizations, each with its own economic axe to grind, are pointing fingers at each other. Here's some background on all the parties and what their arguments are: "Battle Over Data Caps Heats Up." Of course, it all started when the U.S. federal government decided that it's okay for ISPs to also own and sell major content -- in competition with other companies that depend on that national infrastructure to deliver their own content.
If you're arrested for, say, a traffic offense, can the police officer search your iPhone? It might depend on whether your iPhone is password protected. This article at ars technica starts by looking at cases in Canada, but ends by looking at the situation in the U.S. "Cops can search mobile phones—only if they're not password-protected." It might influence whether you routinely password protect your iPhone when out for simple errands in your car.
I have been writing about smart glasses lately, and specifically, Google Glass. Joshua Topolsky got up close and personal with a pair recently and wrote up a terrific article on his experiences with the device. This is must reading. "I used Google Glass: the future, with monthly updates."
Image Credit: The Verge
Even more to the point is how smart glasses and iWatches will interact with human beings for good or evil. For example, at one time, all analog cell phones did was allow us to make a phone call. We paid for simple voice connectivity. Today, a modern smart phone is a target on the Internet for criminals, and our personal behavior is monitored by both the manufacturer and the carrier. Is it likely that smart glasses and wearable devices will turn the tide? Or will they continue down the path of doing us more harm than good? Brian Hall looks at these technologies in terms of advertising and intrusion: "Apple iWatch vs Google Glasses and the Next UI Battle."
Is Java doomed on the desktop? Are the security issues just too big to deal with in a modern threat environment? Does Oracle need to change its ways? Do you have Java installed on your Mac, and, if so, why? This and more is discussed in "After so many hacks, why won't Java just go away?"


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Palestinians vandalize Obama banner ahead of visit
JERUSALEM (AP) — Palestinians have vandalized a banner bearing President Barack Obama's image just days before his visit.
The Palestinians tore down the banner, hurled shoes at it and spray painted it with swastikas. Associated Press TV video showed a taxi driving over the banner before it was set on fire in the West Bank town of Bethlehem on Monday.
Obama arrives in Israel on Wednesday. He heads to the West Bank Thursday.
The banner with Obama's picture is among many hung by activists, asking the president to take note of the lack of 3G frequencies in the West Bank. Israeli authorities control cellular networks there and they have not granted Palestinian telecommunication companies 3G.
The Palestinians have long felt aggrieved by the U.S., accusing it of being biased toward Israel.

subset: commoncrawl


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Tuesday, February 09, 2010
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About Me
- Lisa
- I am a coupon fanatic, sweepstakes enthusiast, and freebie lover. I am the mother of one 4 year old little boy, and work full time outside of the home. Even though my husband and I both work full time, we have trouble making ends meet. I have taken up trying to save money as a hobby and I really enjoy showing off my freebies and savings.
Tips and Helpful Hints
*Purchase a small coupon organizer to keep your coupons organized so they'll be easy to get to when you're looking for them. Keep it with you, just in case a good deal appears!
*If you will be filling out forms for free samples and coupons, I suggest you download RoboForm. This will fill in your entire form with one click!*A manufacturer's coupon is one that comes straight from the company, such as the newspaper coupons, coupons you get in the mail, or coupons found inside product packaging. You can use these coupons wherever the product is sold.
*A store coupon is one that comes from the store itself. You can find these inside stores, in store advertisements, online, through emails, etc. You can use these coupons in that particular store only.
*You CAN use a manufacturer's coupon and a store coupon at the same time on the same product. For example if Walgreens has a store coupon for $1 off shampoo, and you have a $1 off coupon from the Sunday paper for the same shampoo, you may use both at once.
*Check out your local Shop N Save, this store runs a special very often. On the specified Thursday buy $50 worth of groceries, get $10 off-No coupon needed!
*Rebates! These require a little work, but are worth it in the long run. You come across rebates in the Sunday paper, or in stores. You'll need the rebate form to fill out, the receipt from the product you purchased, and possibly the UPC code from the product packaging.
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Go HERE and print 3 rebate forms from SC Johnson. Purchase three participating products and get $5 rebate! Each household is eligible for 3 seperate rebate checks. Brands include Ziploc, Glade, Windex, and more. *Expires July 30, 2010.
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Fleet Safety
Our sales representatives spend significant amounts of time driving and are at risk of being involved in road traffic incidents. At the end of 2011, Pfizer had approximately 33,000 cars and 3,000 motorcycles worldwide covering over 825 million miles per year (and representing twice the amount an average person drives).
In particular, we aim to:
- Help ensure that our colleagues are among the safest drivers on the road. We do this through creating better awareness and helping our colleagues improve.
- Reduce risk to our colleagues and those with whom we share the road.
- Educate our colleagues worldwide about driving risks including distractions while driving.
Notable actions we are taking to safeguard our sales colleagues and those that share the roads with them include:
- Implementing a Global Fleet Safety Standard and providing a structured support system that helps to provide a platform globally.
- Providing safety guidance for colleagues where we provide motorcycles.
- Improving driving performance and measures for success.
- Ensuring the entire Pfizer fleet is safely selected, maintained, and inspected.
Recent performance achievements include:
- Over a 50% reduction in motor vehicle collisions in the United States – the first country to launch its fleet safety program (2008-09).
- Creation of a global dashboard and goals to help reduce collisions worldwide (2009). Enabled a global management system that provides a platform of tools and resources to build a consistent program, enabling countries to tailor their programs to local markets (2010).
- An 80% roll-out of the global fleet safety program in countries with large and medium-sized vehicles (end of 2011).
- Launched our first fleet safety motorcycle program in Pakistan (2011).


text: Conditioning Class 3 views Conditioning Class Details More Info: http://www.crossfitgongfu.com Comments Leave a Reply Cancel replyYou must be logged in to post a comment. Feed CrossFit Gong Fu published - 8 months ago. Details Start: 02/05/2018 18:00 End: 02/05/2018 19:00 Timezone: UTC CrossFit CrossFitexercisegong fu Where 26 St Albans Ln, London NW11 7QE, UK Public Transport Golders Green Station 0 miles Golders Green Station 0.1 miles Publisher Published on February 9, 2018 by CrossFit Gong Fu Member since: February 3, 2017


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Robert KraayNFL Draft Prospect
Offensive Line
Ht: | Wt:
News | Stats | Stat vs. Team | Targets | Injury | Depth Chart | Roster
|NFL | Kraay works out at Pro Day
Fri, 27 Apr 2007 23:46:06 -0700
Gil Brandt, of NFL.com, reports Air Force OL Robert Kraay measured a height of 6-foot-8 and a weight of 277 pounds at his Pro Day. He ran the 40-yard dash in 5.07 seconds and 5.08 seconds, the short shuttle in 4.64 seconds and the three-cone drill in 7.52 seconds. He measured a 35-inch vertical jump, a 9-foot-7 broad jump and completed 12 repetitions on the 225-pound bench press.
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Anderson Varejao to have surgery on Thursday
CLEVELAND (AP) — Cavaliers center Anderson Varejao needs surgery to repair a torn leg muscle and could miss two more months, a major blow to a young Cleveland team struggling through another miserable season.
The NBA's leading rebounder, Varejao got hurt in a Dec. 18 game against Toronto. The injury was initially diagnosed by team doctors as only a bruised right knee, but as his symptoms persisted, more tests were performed and revealed a "longitudinal split" between Varejao's quadriceps and knee. Also, ultrasound imaging revealed tissue underneath the muscle tear was herniating.
Varejao will have surgery on Thursday, and the team said he will be sidelined a minimum of six to eight weeks. The team said Dr. Richard Steadman in Vail, Colo., provided a second opinion on the injury.
Cavaliers coach Byron Scott is hoping Varejao can return this season. Scott said he has not spoken to Varejao.
"I may just go up to him and give him a big hug and tell him it's going to be OK," Scott said at the team's morning shootaround.
This is the third straight season that Varejao has been sidelined for significant time with a serious injury. He missed 51 games in 2011 with a torn ligament in his foot and 41 games last season after breaking his wrist. One of the NBA's scrappiest players, Varejao was playing at an All-Star level when he banged his knee last month and went down with what appeared to be a routine injury.
However, it's much worse and the Cavs are again without an important piece as they try to rebuild.
Cleveland has had more than its share of injuries in the past few seasons. Point guard Kyrie Irving, last season's rookie of the year, missed 11 games earlier this season with a broken finger and he's one of three Cavaliers who have had to wear protective face masks to protect broken facial bones.
Scott has only had his full complement of players for seven games this season. The Cavs are 8-28 heading into Wednesday night's home game against Atlanta.
"It's real tough," Scott said. "You're disappointed, frustrated and (ticked) off. You have so many different emotions going through your head, but what can you do? Everybody in this league has to deal with injuries and we've had to deal with them for three straight years. You just got to keep playing hard with the guys that you have."
Varejao's injury may also change other plans for Cleveland. The Cavs were likely to explore trade possibilities for the 6-foot-11 Varejao to acquire more future draft picks. But now that he's hurt, the Cavs are stuck and have to hope youngsters like Tristan Thompson and Tyler Zeller improve with more playing time.
"When you have a big blow like this, you're going to have guys get a golden opportunity," Scott said. "When you have an injury like this there is always a silver lining."


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Wilcox was presented with the honor at the Monticello High School Christmas Music program on December 16.
Wilcox was honored for his extensive commitment to the youth of Monticello. He has been heavily involved in a host of youth sports programs, with particular emphasis on the wrestling and football programs.
In a letter nominating Wilcox for the award, Monticello City Councilman Tim Young writes, "Over the past 10 years, I dare say that no other individual has put in more volunteer hours with the youth of our community.
"He has headed up the Rowdy Boys Wrestling program in Monticello for many years, which has brought thousands of people to town and has been a great boost to local businesses.
"In addition to running the youth wrestling program, he has been heavily involved in youth football and High School football.
"Because of his dedication to the youth of Monticello and his belief that character can be shaped through sports, he has had a great influence on the many kids and adults with whom he works.
"Coaching youth programs is often a thankless job requiring an enormous amount of time and effort, but R.L. has continued doing it year after year.
"I believe that his love for kids and his dedication to them is something that has made Monticello a great place to be a kid.
"In my experience, there are not many parents who step up to the plate and put in effort trying to help every kid they can, but R.L. is one of those individuals that shows each kid he works with that he cares.
"Because of this, he has been able to help our youth become the best they can be. I feel that it is time that Coach R.L. is recognized by the citizens for the great contribution he has made to our kids."


text:
Suzanne Dunsmith
Population Projections Unit
Telephone: +44 (0) 1329 444652
Categories: Sub-national Population Projections, Population, Population Change, Population Projections
Frequency of release: Ad-hoc
Language: English
Geographical coverage: England
Geographical breakdown: Local Authority and County
These projections update the 2010-based projections. They are based on the latest population estimates data published on 25 September, which take into account results from the 2011 Census.
London, the East and the South East are projected to grow at a faster rate over the 10 year period to 2021 than England as a whole.
The average annual percentage growth rate for England remains the same as in the 2010-based subnational population projections over the 10 year period to 2021 at 0.8 per cent.
These projections are known to over project the number of births at a national level. This particularly affects some areas where the 2011 population estimates have higher numbers of women aged 16-44 than in the 2010 estimates. Therefore caution should be used in the application of these projections for planning purposes at the younger ages.
Subnational population projections use past trends to project forward the population to give an indication of the future population. These projections are based on the 2011 mid-year population estimates published on 25 September 2012 using recent trends as used in the 2010-based subnational population projections. They are available to 2021 for English local authorities by single year of age and sex.
Subnational population projections are used as a common framework for local area resource allocation, planning and policy making in a number of fields such as health and education.
The projections are not forecasts and do not take any account of future government policies, changing economic circumstances or the capacity of an area to accommodate the change in population. They provide an indication of the future size and age structure of the population if recent demographic trends continued. Population projections become increasingly uncertain the further they are carried forward, and particularly so for smaller geographic areas.
Data in this release have been published unrounded to facilitate onward processing. Users are advised that they should use these data aggregated to five year age groups and rounded.
These National Statistics are produced to high professional standards set out in the Code of Practice for Official Statistics. They undergo regular quality assurance reviews to ensure that they meet customer needs. They are produced free from any political interference.
Subnational population projections Quality and Methodology Information (216.3 Kb Pdf) .
Subnational population projections across the UK (157 Kb Pdf) .
Accuracy report (491.3 Kb Pdf) .
These National Statistics are produced to high professional standards and released according to the arrangements approved by the UK Statistics Authority.


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I agree with Becky Pup! That was pretty funny. I'm still chuckling over it.
Hugs about your grandfather Becky. Next month will be 20 years since Mom died and it still hurts.
How often do you have doulas Leah? I think it is more a Western Coast thing as there aren't any around here that I have ever heard of. I'd love to do that, but my chronic shingles probably wouldn't be the best fit.
Though tomorrow marks the second anniversary of the start of the rest of my life. I am way healthier even now then I was 2 years ago and went into hospital for the epilepsy clinic. It was the night of the 28-29 when I stopped breathing and almost died. The nurse found me blue cold and unresponsive with O2 sats in low 30's. I was supposed to be discharged, but woke up vomiting so they kept me again. It was such a gift. The CPAP machine has made me almost normal! (No comments Becky and Pup it's too easy I walked right into it so you can't tease me!)
Congrats on entering the challenge too. I do believe the theme will be x (or ex) marks the spot. I almost said that last week too.
Man is it hot here. It's been in mid 90's with heat index over 105. Poor Phin does not like it at all. I know you're not supposed to shave fluffy dogs in the summer since the fur helps cool them too. But since he has spitz in him I think the heat is really doing a number on him. He's not as spunky as usual and has had bloody diarrhea today. It gets stuck in his fur. I need to shave his butt. (TMI, I know)


text: International organizations play an increasingly wide-ranging and consequential role in creating, interpreting, and securing compliance with international obligations. This course will address the legal issues arising from the creation and operation of international organizations, as well as the concerns and challenges that the actions of such organizations present, both on the international plane and in national courts. Topics covered will include the United Nations Security Council's role in sanctions and peacekeeping, the dispute settlement procedures at the World Trade Organization, and "technocratic" regulation by the International Civil Aviation Organization. This course complements and does not overlap with courses and seminars such as International Human Rights and International Trade.


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Harold Swanagan joins Notre Dame basketball staff
Notre Dame men's basketball coach Mike Brey didn't have to look far to fill his recent assistant coaching vacancy, handing it almost immediately to coordinator of basketball operations Martin Ingelsby.
And to replace Ingelsby, Brey's search didn't exactly require time with the Hubble telescope, either.
Former Irish forward Harold Swanagan is the new coordinator of basketball operations, the school announced Wednesday, sliding over from his current role as coordinator of student welfare and development at the university.
Swanagan played with the Irish from 1998 to 2002 -- with Brey coaching him in his final two seasons --serving as a tri-captain as a senior. At the time of Ingelsby's promotion, Brey said he was in no hurry to fill the new basketball operations position and might wait until August to hash it out. Apparently, though, there was no time like the present to bring Swanagan aboard.
"He already has developed deep relationships with our current players from his former position in the Student Welfare and Development Office," Brey said in a statement. "He was a great captain and leader for us as a player and always was a guy who put the team first. I am thrilled to have Swanny back with us."


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October 06. 2017 11:55PM
Bedford Medical Center opens with six practices
By KIMBERLY HOUGHTON
Union Leader Correspondent
Cutting the ribbon at the newly renovated Bedford Medical Center are Dr. Ed Schiavoni of Southern New Hampshire Internal Medicine Associates, left, and Dr. Ted Brooks of Derry Medical Center and Derry Imaging. (COURTESY)
CMC leases Bedford property for vein clinic, medical groups
Derry Medical Center opens office in Bedford
Bedford Medical Center has opened its newly renovated space on South River Road, which consists of a group of independent medical practices.
"We are so happy to join together with our medical partners to extend our model of care to the greater Bedford and Manchester community," said Ted Brooks, Derry Medical senior partner.
Derry Medical Center opened its fourth primary care office — the first one housed on the west side of the Merrimack River — earlier this year in temporary space within the lower level of the building at 160 South River Road.
Last month, the renovations to the second floor were completed and the relocation to the redesigned medical suite for six different practices became official. The facility's title — Bedford Medical Center — became official as well.
In addition to Derry Medical Center, the medical practices housed in the complex include Derry Imaging Center at Bedford, Southern New Hampshire Internal Medicine Associates, Quest Diagnostics, Granite State Gastrointestinal Consultants and Granite State Podiatry.
"The real pleasure of the facility for all of the different practices was being able to have this one area where a patient can see their primary care, get an X-ray at the imaging center, get a mammogram or get their lab work done," said Susan Chadwick, director of marketing and public relations at Derry Medical Center. "It is a very unencumbered process."
The building has been transformed from a dated, nearly empty building into a modern facility providing vital medical services for people in the area, according to Chadwick.
"The real game changer, I believe, is that Derry Medical and all the practices are independent. They are neither hospital-owned, nor hospital-affiliated," said Chadwick. "It is a different model of care that our patients appreciate. They can go to any hospital that they need to. They are not restricted in any way."
Derry Medical Center has four doctors and two mid-level physician assistants or nurse practitioners stationed at the new facility, and there is room for growth, Chadwick said. There are numerous exam rooms and staff members between the six practices, she added.
Ed Schiavoni of Southern New Hampshire Internal Medicine Associates said that partnering with Derry Medical, Derry Imaging and other medical practices has been a great model in other Internal Medicine locations, enabling the group to continue to provide high quality, patient-centered care for its patients.
Having a new Quest Diagnostics lab in Bedford is a huge benefit and convenience for residents in town and surrounding communities, said Chadwick. She explained that it helps promote the one-stop medical shopping model.
Bedford Medical Center has extended hours from 8 a.m. to 8 p.m. Monday through Thursday, and from 8 a.m. to 5 p.m. on Fridays.


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Main Site - :: Why Won't God Heal Amputees? ::
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For a guy who got so pissed off that I "refused" to answer his questions, he doesn't seem too eager to actually say anything much now I've answered them.....
Seriously, you guys are the meanest people I have ever met. I hope you are happy and feel really good about yourself.
i'm working on it. And for the record, I was never "pissed off" with you... I was upset for being censored by the Moderators. Some censor is good and needed. But not for anything I did in here.
Fran,I've now answered the 3 additional questions you were so desperate I answer. You have also not answered MY question from the main thread - "why is resurrection MORE reasonable that my alien explanation"?


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Hooded Scarves & Gloves
Find fashionable sewing patterns for gloves and hooded scarves. You can choose complimentary fabric to match your winter wardrobe. Plus, these 10 patterns are quick and easy-to-stitch!
Stay cozy and chic with these hooded scarf and fingerless gloves patterns. The Hooded Scarves & Gloves sewing pattern book has beginner sewing patterns, but it's also filled with interesting patterns that will intrigue the expert, too. Youll use fabrics like fleece, fashion prints and fur in styles that are perfect for you and your friends.
Skill Level: Easy
- Find full-color photographs, easy-to-read instructions and full-size templates for each pattern.
- Easily go from day to night with a reversible hooded scarf.
- Make matching fingerless glove patterns with extra fabric.
- Stitch up a hooded scarf or a pair of fingerless gloves in hours. They're great for last-minute, DIY gifts!
Skill Level: Easy
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'The Walking Dead' renewed for Season 5; Scott Gimple at the helm
Posted in: TV
"The Walking Dead" has been renewed for a fifth season.
AMC announced Tuesday that its hit zombie drama, based on the Robert Kirkman comic book, will lumber back for another run of installments, hardly surprising news considering the massive ratings the show is enjoying. The series has become television's most-watched prime-time drama, with its recent Season 4 premiere attracting some 16.1 million viewers.
Scott M. Gimple also is set to return as show runner, AMC confirmed.
"We are very happy to make what has to be one of the most anti-climactic renewal announcements ever: 'The Walking Dead' is renewed for a fifth season," said Charlie Collier, AMC president, in a statement issued by the network Tuesday. "This is a show that has erased traditional distinctions between cable and broadcast. Its expanding base of passionate fans has grown every season…"
Check out two images above from Sunday's upcoming episode "Indifference," and click here to find out what executive producer Kirkman had to say about the direction of the show as Season 4 continues to unfold.
(Here's a hint: David Morrissey's The Governor is poised to return "at any moment.")
— Gina McIntyre
Follow us on Twitter: @LATHeroComplex
'Walking Dead' gets Season 4 premiere date
Walking Dead Escape not for the faint of heart
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'Walking Dead': Glen Mazzara on war, revenge, hope
Glen Mazzara: Comic fans won't guess what's coming
'Walking Dead': Michael Rooker on tough love
'Walking Dead's' Danai Gurira on Michonne
Q&A: Norman Reedus is go-to guy in zombie times
Steven Yeun: Glenn is beating heart of 'Walking Dead'
Return to: 'The Walking Dead' renewed for Season 5; Scott Gimple at the helm


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Featured News - Current News - Archived News - News Categories
Renowned talk show host, producer, publisher and actress Oprah Winfrey will visit the "Late Show" with David Letterman, Thursday, Aug. 1 (11:35 p.m.) on the CBS Television Network. This will mark her second-ever visit to the "Late Show," and her first since her much-talked-about appearance on Dec. 1, 2005.
Winfrey gained international recognition as the host of the multi-award-winning syndicated talk show, "The Oprah Winfrey Show," which ended its run in 2011. The chairwoman and CEO of Harpo Productions, her film and television production company, she is a noted philanthropist, the publisher of the lifestyle magazine, "O: The Oprah Magazine," and the chairwoman, CEO and CCO of the cable television network, OWN: The Oprah Winfrey Network, which launched Jan. 1, 2011. Winfrey is also an acclaimed actress, who was nominated for an Academy Award for her role in the film "The Color Purple."
Winfrey stars in the upcoming film "Lee Daniels' The Butler" as Gloria Gaines, wife of Cecil Gaines (Forest Whitaker), who, as a White House butler, eyewitnesses notable events of the 20th century during his tenure. The film is based on the real-life account of Eugene Allen, who served as a White House butler during eight U.S. presidencies, from 1952 to 1986. The film is set for release in theaters Aug. 16.
Winfrey's "Late Show" appearance comes nearly eight years after her first visit to the CBS broadcast. Prior to her 2005 appearance, Letterman had expressed his long-standing desire to have Winfrey as a guest on the show. Her "Late Show" visit on Dec. 1 coincided with the red carpet premiere for the Broadway musical "The Color Purple," which she produced.
With fans and media cheering on, Letterman famously escorted Winfrey after the interview taping down Broadway to The Broadway Theatre, directly across the street from the Ed Sullivan Theater, to the musical's premiere.
Also visiting the "Late Show" Thursday is actor Paul Rudd, who stars in the new film "Prince Avalanche."


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Atlassian Sourcetree is a free Git and Mercurial client for Windows.
Atlassian Sourcetree is a free Git and Mercurial client for Mac.
Copyright © 2007-2009 SystemInPlace, Inc.
ApplianceKit is free but copyrighted software. Usage, redistribution and modification of this software is allowed under acceptance of the terms present in the LICENSE AGREEMENT found in the COPYING file.
1. What is ApplianceKit and why is it important?
ApplianceKit is a platform for easily provisioning and creating appliances. It is considerably more powerful than other provisioning tools, allowing for custom partitioning schemes and other nice things.
However, the big thing with ApplianceKit is ApplianceXML, which describes how a software appliance is created and installed. As an example, the following XML snippet creates a Debian Lenny install and denotes that you want irssi installed in it.
<?xml version="1.0" standalone="yes"?> <appliance>
<description>Irssi appliance</description> <author><name>William Pitcock</name> <email>email@example.com</email>
</author> <distribution>lenny</distribution> <packagelist><package>irssi</package>
2. System Requirements
You need:
- Linux 2.6 or later
- Python 2.5 or later
- A supported virtualization technology: xen, vserver or qemu/kvm [experimental].
- The Xen support requires an LVM volume. LVM is the proper way of doing Xen anyway. If you are not using Xen, then LVM is not required.
3. Installation procedure
See the INSTALL document.
4. Reporting Bugs
See the instructions at http://www.appliancekit.org/.


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Thursday, April 9, 2009
French toast
When was the last time you had good French toast? Don't answer that if you can eat gluten. But for those of us who are gluten-free, most of our bread options just don't work for French toast. Put most gf breads in an egg wash and they fall apart, or just don't taste great. My mind was blown a little bit when I came across the concept of making french toast out of sponge cake in The Gourmet Jewish Cook. Luckily it was just Alex and I last night at our seder, so we have plenty of cake left to make French toast with for breakfast. Ooh it was yummy. I topped mine with citrus mascarpone, which I really want to eat out of the bowl with a spoon, but if I didn't have any of that I would top the French toast with cinnamon and sugar.
Sponge cake French toast
Inspired by the Gourmet Jewish Cook by Judy Zeidler
1/3 c milk
1 egg
2 T orange juice
4 slices sponge cake, about an inch thick
citrus mascarpone frosting or cinnamon and sugar, for topping
Beat the milk, egg and orange juice together. Heat a small pan with a tiny bit of butter or oil, and quickly dip one slice of cake in the egg, flip, then transfer immediately to the hot pan. Don't let the cake soak too long in the eggs, because it will absorb a whole ton of liquid and be soggy. Cook 2-4 minutes on each side, then transfer to a plate and top with frosting, which will melt a little and be so yummy. Repeat with remaining cake slices.
4 comments:
Every since I first looked at this a few days ago, I've been craving french toast. Which is terrible since I was already craving pound cake *and* had a goal of loosing a few lbs by May...oh, this beautiful french toasted poundcake is so tempting/tauntingReplyDelete
Beautiful pictures! And happy Passover! (And happy belated birthday!)
I'm so interested in that cookbook you wrote about, too. I'm going to have to seek it out...
Mmm. Bet that is delicious!ReplyDelete
Subscribe to: Post Comments (Atom)


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Communications, Marketing, and Community Relations
Related Links
Contact Information
Macon Cove Campus
Farris Building, Room 1002
Phone: 901-333-4024/4116
Fax: 901-333-4503
Executive Director: Daphne J. Thomas
Email: firstname.lastname@example.com
Coordinator of Projects, Advertising Media Relations: Robert Jackson
Email: email@example.com
The Communications, Marketing, and Community Relations Department is Southwest's voice in the community and within the College. News releases; The Southwest Scoop, an online newsletter; Southwest Now Magazine; electronic messaging center; websites; Southwest Now, a magazine style TV show, and publications enable the Department to reach students, supporters and the community; and to promote programs, services and opportunities that enhance individual lives and the communities in which they live and work. The Department publicizes the successes and accomplishments of Southwest students, faculty and staff.
Communications, Marketing, and Community Relations supports the College and its mission with strategic Communications and Marketing, advertising, photography, copywriting, and creative and printing/duplicating services. The department produces all major College publications, non-credit course schedules, student handbook and athletic media guides along with a wide variety of other publications including brochures, pamphlets, videos and multimedia presentations as requested.
Our College magazine, online newsletter, promotional television show, and public website have earned recent national and international awards of excellence.
The College public and athletics websites are maintained through Communications, Marketing, and Community Relations. The Webmaster's Office has been honored with numerous national awards for the websites.
Communications, Marketing, and Community Relations continually strives for a highly electronic, print and multimedia profile that reaches potential and current students, supporters and the community on a local, regional and national level.


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Convicted Maine drug dealer faces sentencing in federal court
PORTLAND, Maine (AP) � A Maine man authorities describe as a key figure in a drug distribution ring faces life in prison at sentencing.
Shareef Nash of Buxton is scheduled to be sentenced Tuesday in U.S. District Court in Portland.
Authorities say the 34-year-old Nash was a top dealer at the Maine end of the drug ring, taking shipments of mostly cocaine that women in the network smuggled inside their bodies on planes and cars from New York. The drugs were distributed in packages to lower-level dealers in the Portland area.
The Portland Press Herald (http://bit.ly/XTER8o ) reports that Nash pleaded guilty to a charge of conspiracy to distribute cocaine base, cocaine and heroin, aiding and abetting. He faces 10 years to life in prison and fines up to $10 million.
Information from: Portland Press Herald, http://www.pressherald.com


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Rachael S. Fox, 87, of Fort Myers, Fla., ended her pilgrimage in this life on Wednesday, May 8, 2013, in Gulf Coast Hospital, Fort Myers, Fla.
Born on Feb. 9, 1926 in Berwick, she was a daughter of the late Cyrus S. and Dollie Johnson Smith.
She was a graduate of Berwick High School, class of 1944. She had lived in East Stroudsburg a number of years, where her children were raised. She was employed as a bookkeeper and investment coordinator.
She enjoyed making jewelry and traveling through the states and Europe.
She was preceded in death by her husband, Walter Fox, and sister, Eileen Miller.
Rachael will be remembered by her three children, Eva Train of Lancaster, David M. Sarley Sr. and wife, Nancy, of Berwyn, and Dolly Jane Sarley of Jeffersonville; her grandchildren, Timothy D. Train, Jonathan G. Train, David M. Sarley Jr., Kathryn L. Boseck and Matthew N. Sarley; her great-grandchildren, Kirsten B. Train, Bryanne E. Train, Joshua L. Train, Ashlea A. Boseck, Courtney F. Boseck, Gracie E. Boseck, David A. Sarley and Daniel M. Sarley. "Forever in our hearts."
Rachael will be laid to rest in Mifflinville Cemetery. A calling will be held from 10 to 11 a.m. Thursday, May 16, at Bill Heller Funeral Home, 633 E. Third St., Nescopeck.
Bill Heller Funeral Home
633 E. Third St., Nescopeck
Rachael S. Fox
Rachael S. Fox, 87, of Fort Myers, Fla., ended her pilgrimage in this life on Wednesday, May 8, 2013, in Gulf Coast Hospital, Fort Myers, Fla.


text:
Windows 10 PRO ISO With Crack + Product Key:
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Meet Madden : St. Paddy's Day Cutie
We know you're going to spend your St. Patrick's Day at a bar. Hell you might even make it a two night event, with it conveniently falling on a weekend. We only ask one thing of you.
- Let us know if you see anyone as cute as Madden at the bar.
I know, it doesn't seem very likely, but how epic would it be if some cute little blonde started stripping for you at the bar after a bit too much Guinness? This is Madden, she apparently has a website by the name of MeetMadden.com, and she would love to sell you pictures of her mostly naked. Enjoy, and Happy St. Patrick's Day!


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Leading Car Rental Service in Pune
There are many Cheap Car hire Companies in Pune . Some of them are providing their services through the internet also. That means you can book your car to hire online also. So select a good car hire company to rent a car from and get a good service.
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Best Car Rental Service in Yedgaon Pune
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Pune to Lonavala Cab
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Pune Airport to Shirdi Cab
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text:
MONTREAL _ Ian Laperriere, the Flyers' gritty right winger, is expected to return to the lineup Saturday afternoon against Montreal, a club source said Friday.
Laperriere skated on a line with Blair Betts and Darroll Powe at Friday's practice. He has been sidelined since April 22, when he blocked a slap shot against New Jersey and suffered a bruised brain, a broken orbital bone and a concussion. He needed nearly 70 stitches to repair a cut above his right eye.
Jeff Carter, recovering from a broken foot, also skated at Friday's practice and scored on a wraparound goal. He looked to be regaining his form, but is still doubtful for Saturday.
"But you never know," said one club source, smiling coyly.
Laperriere, the Flyers said, has been cleared by a neurologist to play.
"He gives us a veteran presence, and he's very energetic in the locker room and on the ice," said center Danny Briere, who called Laperriere the Flyers' best penalty killer. "...And obviously he's tough to play against."
The Flyers would not allow Laperriere or Carter to talk to the media.
The Flyers have a 2-1 series lead over Montreal in the Eastern Conference finals. Saturday's game is at the Bell Centre at 3 p.m. on NBC.


text:
Racetams with NDRIs
Racetams with NDRIs
Jun 13, 2013, 05:17 PM
Post #1
Group: Basic Member
Posts: 6
Joined: May 14, 2013
Member No.: 35112
Looking for some feedback about taking racetams with NDRIs.
The main question is that when I research racetams the thoughts about their exact moa seem to vary from source to source. Some however report that racetams have an agonist effect on NMDA as well have being similar too and having a similar action as GABA.
The moa of NDRIs is pretty self explanatory, hence the name. There is clear evidence that NMDA antagonist slow tolerance to opiates and to some degree NDRIs. Thus one could assume by default that NMDA agonist (racetams) could possibly cause an increased tolerance to NDRIs and actually reduce their effectiveness. Also GABA is released by the brain as an inhibitory substance when Dopamine and Norepi are in high amounts to counter act or balance the effects. If racetams act similar to GABA then that aswell might reduce the effectiveness of NDRIs moa. I recognize this is truncated and could be described in more detail but those familiar with these substances will get the idea. Im simply looking for some thoughts on combining these 2 substances. Good idea, Bad idea, etc. And as always nothing would be taken with discussion with a doctor first.
Jun 13, 2013, 05:43 PM
Post #2
Group: Basic Member
Posts: 1954
Joined: Oct 17, 2006
From: Bay area CA
Member No.: 5877
If you want my honest answer, I say mu. It is completely dependent on what NDRI you are taking, and what exactly you mean by effectiveness. What you are not likely to gain from that combo is cognitive health.
Jun 13, 2013, 06:08 PM
Post #3
Group: Basic Member
Posts: 6
Joined: May 14, 2013
Member No.: 35112
What about that combo is anti- cognitive health? And do you mean subjectively as in felt or precieved benifit or objectively as in actually not healthy for the brain or both?
Jun 13, 2013, 06:24 PM
Post #4
Group: Basic Member
Posts: 6
Joined: May 14, 2013
Member No.: 35112
NDRI being spoken about would be extended release MPH. If one has found MPH to be a huge help and has been able to stay on the same dose for a while and wanted to slowly add supplements that would be supportive and aid cognitive ability and health what would you recommend?
Jun 14, 2013, 09:20 AM
Post #5
Group: Basic Member
Posts: 1954
Joined: Oct 17, 2006
From: Bay area CA
Member No.: 5877
I would recommend you try not taking anything and see what sort of effect your wonder drug is actually having on you. To say that the mechanism of action of NDRIs is understood is a gross misrepresentation of the literature. Anyone who tells you otherwise is 1.) ignorant 2.) not a reliable source of information.
I would be happy to challenge anyone who makes said claims with a literature review.
Fast forward to page 10:
I am fairly confident nothing has really changes significantly since 2012.
That being said, it would be very irresponsible of me to suggest that anyone should be taking something which is unnecessary and may cause life long changes not only to you, but potentially to your offspring as well.
Jun 14, 2013, 10:55 AM
Post #6
Group: Basic Member
Posts: 6
Joined: May 14, 2013
Member No.: 35112
I recognize there is much about MPH that is not fully understood and that my original post was very truncated and lacking detial. However I think that the overall literature and research into MPH is pretty clear and consistent on its MOA with in the brain. How that MOA improves certain illiness or improves baseline cognitive function is not as fully understood but is still well understood. MPH has been around as an RX for 60+ years and there are studies showing its long term effects. I would not make the same argument for amphetamines because much more comes into play when taking into account the reversal of DAT etc. But I think even they are well understood. I also never claimed MPH to be "a wonder drug" it is however a helpful RX for many people who are in need of it and had a great safety profile when used appropriately especially when an extended release version is used. One is generally able to remain on the same dose long term with much improvement in symptoms. I do respect your willingness to be responsible and not give recommendations about an RX med. I would never recommend others taking or mixing any RX without consultation, work up, and a script from a qualified Dr. I'm just curious about your first post that racetams + NDRIs is anti cognitive health. I'm not trying to be argumentative and am happy to be corrected where wrong I simply want to learn.
Jun 14, 2013, 03:00 PM
Post #7
Group: Basic Member
Posts: 1954
Joined: Oct 17, 2006
From: Bay area CA
Member No.: 5877
I would argue that the mechanism of action is at best trivially understood. Ephedra has been around for thousands of years, but that does not make it safe or well understood.
"The mechanism of action of ADHD medications is not well-understood (Heal et al. 2011). Most studies have focused on synaptic reuptake or release of neurotransmitters (Swanson and Volkow 2002) but this may be only one mechanism. Administration of methylphenidate in adolescent rats has been reported to upregulate over 700 genes in the striatum"
Unless you know your brain voltage, speed, rhythm and synchrony, there is no way to quantify weather or not you are receiving benefit or doing harm. That said, it is probably safe enough. What effect will it have? Who knows, that is what guinea pigs are for. No one has come close to studying anything remotely similar that I am aware of.
Jun 15, 2013, 10:47 PM
Post #8
Group: Basic Member
Posts: 6
Joined: May 14, 2013
Member No.: 35112
Flex, thanks for the input, I'm new to this site and you seem intelligent and well read so I'm grateful for the dialog. I see what you're saying in your last post and think I misread you at first. I recognize that the overall moa is maybe not well understood. As we make advances neuroscience, neuropharmacology, and over all medical science we are going to probably constantly discover that the moa of many chemicals whether from drugs, supplements, food, or even those inherent within our self are not well understood. When I said MPH was well understood I was speaking specifically to its ability to act as a NDRI. Now I recognize that there is still areas here that are not fully grasped however I do think the overall view within the medical comunity is that MPH does act as an NDRI and that this moa is effective in treating certian conditions. I also think the general concensus is that it is generally safe when used used aappropriately.
"Methylphenidate is commonly used for the treatment of attention-deficit hyperactivity disorder (ADHD). Its efficacy in improving the core symptoms of ADHD, as well as some of the aggressive and oppositional behaviours, is well documented, based on a large volume of research. Methylphenidate has a wide margin of safety and relatively mild adverse effects, most commonly appetite suppression and insomnia. Methylphenidate is a rapidly absorbed medication that, in its d-isomer form, readily penetrates the CNS, particularly the striatum." (Wolraich 'Pharmacokinetic considerations in the treatment of attention-deficit hyperactivity disorder with methylphenidate.')
Either way I have no real desire to debate out all the effects of MPH there are many people who have greatly benefited from it and many who haven't.
However Im still curious as to your first post about combining it with a ractem being unhealthy. Im not saying I even want to take them together. There are many accounts of people who have but as my first post pointed out im really looking for some info on how there moas would interact.
Jun 16, 2013, 08:30 PM
Post #9
Group: Basic Member
Posts: 1954
Joined: Oct 17, 2006
From: Bay area CA
Member No.: 5877
I did not mean to imply the combo was inherently unhealthy, but rather that MPH is unhealthy. As someone who likely induced psychosis due to stimulant use as a child, I cannot help but raise a red flag when I see something touted as safe when it has fucked so many people up. Honestly it is probably not going to make a particle of a difference if you add piracetam or not. By definition, one should not notice ANYTHING from a nootropic, including cognitive enhancement. One would be able to detect cognitive enhancement at the population level only (research studies). That said, if you actually look at the studies on piracetam, they are complete and utter bullshit for the most part, and thus any claims, including those mentioned below are likely inaccurate bullshit as well.
Here's a little excerpt from a project I was working on that fell through about a year ago:
In 1964, a new compound, piracetam, was synthesized by Romanian chemist/psychologist, Dr. Corneliu E. Giurgea. Giurgea described his new drug, piracetam, as being nootropic. The term "nootropic" come from the Greek words nous, "mind" and trepein, "to move towards". Giurgea established nootropics as a new class of compounds by laying down general guidelines that ought to be met before a substance may claim nootropic status.
Giurgea's suggested that in order for a compound to be considered a nootropic, a compound must facilitate the learning process, or enhance memory by some measurable index. A nootropic should protect the brain from physical or chemical injury, preserving cognitive function even under conditions known to cause impairment such as lack of oxygen, stress, alcohol exposure, etc. Exhibit few side effects and extremely low toxicity, while lacking the pharmacology of typical psychotropic drugs (motor stimulation, sedation etc).
Since Giurgea's original criteria were first published, there has been little agreement as to what truly constitutes a nootropic compound. The most well defined criteria to date were established by Skondia in 1979. Skondia utilizes a metabolic approach, taking into account the pharmacological mode of action.
Skondia's Nootropic Criteria:
I. No direct vasoactivity
- A. No vasodilation
- B. No vasoconstriction
II. EEG activity: No change in basic rhythm
- A. Quantitative EEG: Increased power spectrum (beta 2 and alpha)
- B. Qualitative EEG: Decreased delta waves and cerebral suffering
III. Must pass blood-brain barrier
- A. Under normal conditions
- B. Under pathological conditions
IV. Must show metatolic activity in:
- A. Animal brain metabolism
- 1. Molecular
- 2. Physiopathological
- B. Human brain metabolism (clinical evaluation)
- 1. A-V differences
- a. Increased extraction quotients of O2
- b. Increased extraction quotients of glucose
- c. Reduced lactate pyruvate ratio
- 2. Regional cerebral metabolic rates (rCMR)
- a. Increased ICMR of O2
- b. Increased rCMR of glucose
- 3. Regional cerebral blood flow: Normalization
V. Minimal side effects
VI. Clinical trials must be conducted with several rating scales designed to objectify metabolic cerebral improvement.
Since nootropic criteria are still widely debated, only compounds classified as nootropic agents by the National Center for Biotechnology Information (NCBI) will be considered as such.
NCBI does not follow the same stringent criteria laid out for nootropics above. Compounds may poses vasodilatory properties, toxicity etc.
First synthesized in 1964, Piracetam is legal to import into the United Kingdom without a prescription and remains an uncontrolled substance in the United States. Piracetam is a derivative of the neurotransmitter GABA (Gamma Amino Butyric Acid). GABA is the primary inhibitory neurotransmitter, and is involved in the regulation of muscle tone.(1) While structurally related, piracetam does not interact with GABA receptors as indicated by low affinity. To date, piracetam's mechanism of action remains unclear.
Piracetam is chemically related to pyroglutamic acid (pyrrolidine Carboxylic Acid). Pyroglutamic acid is found in cerebrospinal fluid and is formed by post translational modification through the deamination of N-terminal glutamine to pyroglutamic acid. A two-month study was carried out in which 40 patients aged 65 and over, suffering from memory problems, received either pyroglutamic acid daily for two months, or a placebo. At the end of the study, the researchers found that the group taking pyroglutamic acid showed significant improvements in memory function, compared to the control group.(2) This may be due to the ability of pyroglutamic acid to improve blood circulation, which has been shown to enhance brain glucose utilization, thereby increasing mental energy.(3)
While an exact mechanism for the effects of piracetam remains unknown, it is likely that piracetam enhances brain metabolism by increasing blood flow, increasing the amount of circulating oxygen, thus enhancing glucose utilization (the primary fuel of the brain) just like pyroglutamic acid. Others have proposed that by interacting with the polar head groups of the phospholipid bilayer of cell membranes, piracetam is able to increase cell membrane fluidity.(4) This would help to support healthy neuron structure, and thus enhance communication efficiency. In reality, piracetam may do all of this and more by stimulating a cascade of events throughout the body. For instance, piracetam exhibits significant antioxidant-like properties due to inhibition of proinflammatory thromboxanes at higher doses (4.8-9.6g).(5) It even has been claimed that piracetam is as effective as aspirin in the secondary treatment of ischemic stroke; however, the sample size of the test group was small.(6)
Piracetam's ability to increase memory in healthy individuals has been noted at dosages of 1600mg, three times daily. Most individuals have very modest memory improvements while on piracetam, but studies have shown that in the case of traumatic brain injury, a greater response may be exhibited.(7) The ability of piracetam to prevent cognitive impairment after traumatic events also has been implicated in reducing the cognitive decline resulting from coronary bypass surgery. It seems piracetam is even able to remediate psychological trauma. Self-reports of improvements in anxiety and depression with associated cerebrovascular disorders have been noted in individuals taking piracetam.(8) This effect is even greater than that observed in memory improvement. One of the most remarkable findings to date is the ability of piracetam to combat the buildup of lipofuscin, a byproduct of the oxidation of fatty acids, in brain tissue associated with chronic alcohol consumption. It appears that piracetam is actually able to prevent the loss of neurons following alcohol binges while promoting greater plasticity.(9)
Piracetam use has been shown to result in a decrease in hippocampal acetylcholine levels, so it is typically co-administered with other cholinergic compounds. In animal models of aging, co-administration of piracetam with choline resulted in a synergystic increase in cognitive performance, with the greatest improvements in those with mild age-related cognitive decline.(10)
Effects can usually be felt within an hour or up to several days after consumption. Full efficacy may take up to a month. Typical dosage is between 800mg and 6 grams daily; with most individuals consuming between 1600mg-2400mg. Piracetam is typically taken in cycles, first daily for 2-3 months, followed by 1 month off. Piracetam may be co-administered with a choline source for enhanced results. While the upper tolerable daily intake of choline nears 3.5g (3500mg); low blood pressure, diarrhea, headache, and overstimulation may be experienced at much lower doses. Most users tend to find the greatest benefit from less than 500mg.
Adverse effects of piracetam are very rare, but may include insomnia, drowsiness and agitation. While most people experience improvements in anxiety, piracetam may worsen symptoms in some individuals. While it is true that piracetam's anxiolytic and antidepressant effects are in fact greater than its effects on memory, please use particular caution if you have anxious tenancies!
Human trials have shown piracetam consumption to be safe over the course of 18 months of investigation, at dosages of 3.2g per day. No significant adverse effects have been shown at doses as high as 20g per day, although the likelihood of headaches is known to increase with quantity consumed -- particularly when combined with choline. Piracetam is known to act synergistically with other compounds such as choline, aniracetam, oxiracetam, etc. Adjust dosage accordingly.
1. Watanabe M, Maemura K, Kanbara K, Tamayama T, Hayasaki H (2002). "GABA and GABA receptors in the central nervous system and other organs". Int. Rev. Cytol.. International Review of Cytology 213: 1–47. doi:10.1016/S0074-7696(02)13011-7. ISBN 978-0-12-364617-0. PMID 11837891.
2. Grioli S et al. Fundam Clin Pharmacol 1990;4(2):169-173
3. Lunshina EV et al. Eksp Klin Farmakol 2002;65(3):3-5
4. Moriau M, et al. Platelet anti-aggregant and rheological properties of piracetam. A pharmacodynamic study in normal subjects. Arzneimittelforschung. (1993)
5. Evers S, Grotemeyer KH. Piracetam and platelets--a review of laboratory and clinical data. Pharmacopsychiatry. (1999)
6. Dimond SJ, Brouwers EM. Increase in the power of human memory in normal man through the use of drugs. Psychopharmacology (Berl). (1976)
7. Batysheva TT, et al. Experience of the out-patient use of memotropil in the treatment of cognitive disorders in patients with chronic progressive cerebrovascular disorders. Neurosci Behav Physiol. (2009)
8. Brandão F, Paula-Barbosa MM, Cadete-Leite A. Piracetam impedes hippocampal neuronal loss during withdrawal after chronic alcohol intake. Alcohol. (1995) Brandão F, et al. Piracetam promotes mossy fiber synaptic reorganization in rats withdrawn from alcohol. Alcohol. (1996)
9. Mondadori C, Ducret T, Häusler A. Elevated corticosteroid levels block the memory-improving effects of nootropics and cholinomimetics. Psychopharmacology (Berl). (1992)
10. Pepeu G, et al. The relationship between the behavioral effects of cognition-enhancing drugs and brain acetylcholine. Nootropic drugs and brain acetylcholine. Pharmacopsychiatry. (1989)) Fontani G, Grazzi F, Meucci M. Effect of piracetam plus choline treatment on hippocampal rhythmic slow activity (RSA) and behavior in rabbits. Life Sci. (1984) Bartus RT, et al. Profound effects of combining choline and piracetam on memory enhancement and cholinergic function in aged rats. Neurobiol Aging. (1981).
Jun 19, 2013, 10:38 PM
Post #10
Group: Basic Member
Posts: 68
Joined: Jan 25, 2012
Member No.: 33923
Nice post and info Flex. I can't say how the moa's would effect each other completely for you, but you should be fine with taking piracetam.
I haven't had any issues with piracetam since I was first introduced to it, aside from headaches in the initial days.
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In this presentation filmed during Agile 2008, David Douglas and Robin Dymond discuss about companies which try to adopt Agile, but don't go all the way, resulting in failure and rejection of it, and predictably having a negative impact on Agile's future.
David Douglas is a career consultant for Fortune 500 and mid-sized companies in a wide array of industries and co-founder of Innovel. Robin Dymond is VP of Innovel, and a leader in training for Scrum, Agile, and Lean methods.
Agile 2008 is an exciting international industry conference that presents the latest techniques, technologies, attitudes and first-hand experience, from both a management and development perspective, for successful Agile software development.
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Tell us what you think
Thats true with everything in this field
Francois Ward
Often, when new methodologies or technologies are introduced, there has been great in depth analysis of the potential pitfalls, and documentation on how to avoid them (often as part of the core methodology or tool or whatever). These are often ignored by teams as "not for us", "doesn't fit in our company", "people would never accept it", etc etc.
So then all of the severe flaws of the methodology, tool, technology, API, whatever which were thought about in the planning stage, are left wide open, and the people blame the methodology. Its -always- like that.
Re: Thats true with everything in this field
Mike Funk
Only large projects?
Rukshan Jayaratna
Recently I've tested out a team where the team PM, was more "Agile Coach" role and the team consisted of a BA plus two developers. The result turned out good. No way of comparison, since from the start of the company we were into Agile.
Insights from presentation
Robin Dymond
Innovel is a leading Scrum, Agile, and Lean training and consulting firm. Industry and academic contribution are core parts of our business. In addition to this presentation, Robin Dymond presented a new training simulation that has been made available at no charge to companies and consultants training businesses to use Agile methods.
Robin Dymond, CST
Managing Partner, Innovel
Assistant Producer Learning and Education Stage Agile 2008


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1 Kansas City (2-14): The Chiefs already have their quarterback � not that it is worth taking one at the top this year � and a good running game. The guy who could be the cornerstone for the entire offense, as well as QB Alex Smith�s protector for next few years, plays left tackle. Luke Joeckel, OT, Texas A&M.
2 Jacksonville (2-14): Unlike the Chiefs, the Jaguars are virtually devoid of talent everywhere. So anyone they choose will be an upgrade. There�s talk they could jettison Blaine Gabbert, their first-round pick two years ago, and go for Geno Smith at quarterback. They�d love to trade down, but if not, they�ll upgrade the pass rush and defensive athleticism instead. Dion Jordan, DE-OLB, Oregon.
3 Oakland (4-12): By far the worst team in drafts over the last decade. But now there�s a new regime under Reggie McKenzie, who learned his trade in Green Bay, one of the best drafting clubs of recent years. Like Jacksonville, Oakland could go anywhere with this pick, but is less likely to look to move down. Eric Fisher, OT, Central Michigan.
4 Philadelphia (4-12): The Chip Kelly no-holds-barred, break-neck offense needs speedy playmakers, something the Eagles already have. What they don�t have: enough big-time defenders. They go for a huge one in ... Sharrif Floyd, DT, Florida.
5 Detroit (4-12): Coming off a distressing collapse in which they gave up 437 points, the Lions must find a way to close the wide-open door to their end zone. They�re fortunate to have several options here, and go for the pass rusher. Ziggy Ansah, DE, BYU.
6 Cleveland (5-11): After holding their breath that the cornerback they seek will be on the board � the previous three teams all have a need there � the Lions can exhale and call the name ... Dee Milliner, CB, Alabama.
7 Arizona (5-11): If they can�t trade down, the Cardinals won�t have to swallow hard to upgrade their offensive line with a proven winner and another Crimson Tide player. Chance Warmack, G, Alabama.
8 Buffalo (6-10): Every team puts up smoke screens before the draft. And the Bills sure seem to have polluted the air with them because we think they aren�t convinced Kevin Kolb or Tarvaris Jackson is more than a backup or fill-in QB. So the first quarterback off the board is ... Geno Smith, QB, West Virginia.
9 New York Jets (6-10): Having finally dealt Darrelle Revis, the Jets could look at a cornerback here, perhaps FSU�s Xavier Rhodes. And, yes, they might have considered Smith. But someone who can get to the quarterback from the outside is a must for Rex Ryan�s defense. Barkevious Mingo, DE-OLB, LSU.
10 Tennessee (6-10): The Titans sang a sour song on defense all through 2012, so it�s time to fix some of that in Music City. They might look at the offensive line, but their needs are so hefty on D, and there are lots of solid prospects on the board. Such as ... Jarvis Jones, LB, Georgia.
11 San Diego (7-9): Another team starting over after the talent base was erased by ill-advised moves in the last few years. New coach Mike McCoy is offense-minded, and he sees all the holes on the line. Lane Johnson, OT, Oklahoma.
12 Miami (7-9): Yet another team needing blocking help. After the Dolphins made so many splashes in free agency, they can afford to fill a void, especially when one of the better offensive linemen still is available. Jonathan Cooper, G, North Carolina.
13 New York Jets (6-10): They didn�t miss on Rhodes, but they will consider an offensive playmaker here such as Tavon Austin or DeAndre Hopkins. In the end, the back end on defense will be the target, and because this seems too high to take a safety, New York grabs ... Xavier Rhodes, CB, Florida State.
14 Carolina (7-9): The Panthers will be tempted to go back to the big guys. Then they will spot the little guy with the game-breaking skills on kick returns, as a receiver and even perhaps in a version of the wildcat. They can�t resist ... Tavon Austin, WR, West Virginia.
15 New Orleans (7-9): The Saints will take about 10 seconds of their allotted time to write down their pick, instantly improving their pass rush with a guy with good feel for getting to the quarterback and plenty of upside. Bjoern Werner, DE, Florida State.
16 St. Louis (7-8-1): The Rams would have liked a shot at Austin � receiver definitely is a need � and could go for one here. But with another pick coming up where it can get a pass catcher, St. Louis opts for the best safety in this draft. Kenny Vaccaro, S, Texas.
17 Pittsburgh (8-8): As the Steelers keep insisting they are not a team in transition, one look at the roster says otherwise. Free agency losses hurt them, and they lack the depth from their contending seasons. First upgrade this year is ... Star Lotulelei, DT, Utah.
18 Dallas (8-8): They would have loved Vaccaro in their secondary. The Rams spoiled that, and the Cowboys consider bolstering their backfield and offensive line before taking the best man still unclaimed. Sylvester Williams, DT, North Carolina.
19 New York Giants (9-7): As the noise reaches a crescendo, with chants from blue-shirted Giants fans of �MAN-TI, MAN-TI,� the Giants fill their need for an inside linebacker with good instincts, passion and leadership skills. Arthur Brown, ILB, Kansas State.
20 Chicago (10-6): There won�t be as much noise when the Bears step up. There will be the same need for a linebacker, especially with Brian Urlacher gone. They find their man in Athens, Ga., who could play inside or outside. Alec Ogletree, LB, Georgia.
21 Cincinnati (10-6): With the Andre Smith free agency situation still cloudy � do the Bengals really want him back? � Cincinnati makes a move to put pressure on the veteran. Or to let him walk. D.J. Fluker, OT, Alabama.
22 St. Louis (10-6), pick from Washington: Wisely, the Rams went with Vaccaro at No. 16 and still get the wideout to boost their passing game at this spot. Deandre Hopkins, WR, Clemson.
23 Minnesota (10-6): With two selections in the next three slots, Minnesota is going to help itself on defense both times. First up, yes, the Vikings see plenty of value in that Notre Dame linebacker. Manti Te�o, ILB, Notre Dame.
24 Indianapolis (11-5): Seeking a pass rusher to replace Dwight Freeney, the Colts look at Damontre Moore of Texas A&M, Datrone Jones of UCLA and Alex Okafor of Texas. Moore is most ready to step in. Damontre Moore, DE, Texas A&M.
25 Minnesota (10-6), pick from Seattle: More help for the interior defense is a real bargain this late in the first round. Although the Vikes are tempted to go for a wideout, they see excellent value in ... Sheldon Richardson, DT, Missouri.
26 Green Bay (11-5): The Packers never expected to be in this position, choosing between the best running back in this crop, the two best tight ends or an effective defensive tackle who never stops coming. Does the question become which helps Aaron Rodgers more, a pass catcher or a running back? Tyler Eifert, TE, Notre Dame.
27 Houston (12-4): The Texans have a very obvious need: finding a receiver to complement the superb but aging Andre Johnson. That void has been a major reason Houston flopped in the playoffs the last two years. There are three possible choices for that position, and the answer is ... Cordarrelle Patterson, WR, Tennessee.
28 Denver (13-3): Getting past the Elvis Dumervil error that made him a free agent will be a whole lot easier when the Broncos find a nice replacement � and a surprise first-rounder who impressed with 4 1/2 sacks in the Alamo Bowl. Alex Okafor, DE, Texas.
29 New England (12-4): Predicting anything Bill Belichick will do, other than scowl or wear a hoodie, is impossible. Clearly, the Patriots need help virtually everywhere on defense, although they should be a runaway winner in the AFC East even if they skip all their picks. Now that would be different for Belichick. Matt Elam, S, Florida.
30 Atlanta (13-3): After giving lots of thought to Alabama RB Eddie Lacy, Atlanta backs off and turns to a defensive unit damaged in the offseason by cuts and defections. With visions of defending Brees and Newton twice a season, they go for ... Desmond Trufant, CB, Washington.
31 San Francisco (11-4-1): The Niners almost won the Super Bowl, and they are loaded heading into the draft. So much so that they don�t have to flinch about grabbing the best guy on their board. No selection for need here. Jesse Williams, DT, Alabama.
32 Baltimore (10-6): The 2013 Ravens already don�t resemble the team that won the championship. Ray Lewis, Ed Reed, Anquan Boldin, Dannell Ellerbe, Paul Kruger and Bernard Pollard � all gone. But GM Ozzie Newsome is one of the best talent evaluators around. He�ll get this pick right. Kevin Minter, LB, LSU.
� Mock draft by Barry Wilner, The Associated Press


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