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Group sues EPA over invasive species regulations
TRAVERSE CITY, Mich. (AP) — An environmental group said Wednesday it has sued the federal government, contending that recently established regulations for ships to treat ballast water before releasing it into U.S. waterways aren't strong enough to prevent more aquatic species invasions.
The National Wildlife Federation's lawsuit asks a federal appeals court to rule that the U.S. Environmental Protection Agency failed to meet Clean Water Act requirements with a permit issued in April that applies to an estimated 60,000 vessels longer than 79 feet. It requires them to install some type of technology — such as ultraviolet light or chemical treatment devices — that would kill at least some organisms in ballast water.
"This weak permit leaves the door open for future harm to our environment and economy," said Marc Smith, senior policy manager for the federation.
An EPA spokeswoman referred a request for comment to the U.S. Department of Justice, which also declined to comment.
Ships are equipped with tanks that can hold millions of gallons of water, providing stability in rough seas. But the brew of water, sediment and seaweed sucked into the tanks while vessels are in port can contain fish, mussels and other critters that are hauled to distant harbors and released. Some of the newcomers have no natural predators in their new environments, allowing them to multiply rapidly, out-compete native species for food and habitat, spread disease and destabilize ecosystems.
At least 185 aquatic invaders have reached the Great Lakes, mostly in ballast water, experts say. Among the most notorious are zebra and quagga mussels, which have done untold millions of dollars in damage and spread all the way to California, clogging pipes at power and wastewater treatment plants. They're also believed at least partly responsible for growth of harmful algae, die-offs of loons and other shore birds and declines of some types of fish.
The EPA permit puts ceilings on the concentration of organisms in ballast water using standards proposed by the International Maritime Organization, a United Nations agency, and adopted by the U.S. Coast Guard in 2012. Additionally, transoceanic commercial vessels are required to exchange their ballast water 200 miles from the U.S. shoreline or rinse their tanks if empty, in hopes that the salty water would kill any freshwater organisms left behind.
But critics say the international levels won't do the job. Some states, including Michigan, have adopted their own rules. New York was preparing to impose one of the nation's toughest policies — requiring ballast water treatment at least 100 times more stringent than the international standard — before backing away last year. The National Wildlife Federation has sued the state for that decision.
The shipping industry says no existing technology could filter or disinfect the water to those higher levels.
Smith said the suit against EPA, filed with the U.S. Court of Appeals for the District of Columbia Circuit, doesn't advocate a particular cleanliness standard but asks the permit be declared noncompliant with federal water quality requirements. That could reopen negotiations leading to stronger rules, he said.
The group also is unhappy about a compliance schedule that would allow some vessels to delay installing the new equipment for many years, Smith said.


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We aim to dispatch in-stock items within two working days of receiving your order. Goods are sent by signed-for courier delivery which delivers next-day to most of the UK. Deliveries overseas generally arrive within one week. If any of your chosen items are not in stock we will make them up to order for you and will contact you promptly to advise when we expect to have them ready for you.
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Anyone who has anxiously awaited a medical diagnosis can attest that not knowing is a particular kind of hell. Once the test results are in, decisions, plans and preparations can begin, but until that point, theres little to do but wait and worry.
So it goes with uncertainty over delayed policy decisions that will affect both the U.S. economy and Americans personal spending decisions. Most people want to know, at least, whats going to go wrong.
Will the payroll tax cut be extended? If not, American worker will pay 2 percent more of their income to the federal government starting in January.
Will the Bush-era tax cuts be allowed to expire?
Will anyone get tax cuts? Where will the cutoff line be?
Will trillion-dollar automatic spending cuts really be allowed to kick in?
What will happen to interest rates?
Will the debt ceiling be raised?
Will the Affordable Care Act go forward or not? How much will it really cost American families?
Will Congress pass a Farm Bill?
Fear echoes loudly through the economy. Because 2012 is an election year, neither party (of the two that could move on these issues) wants to cooperate with the other to get something done until after Nov. 6. Progress is stalled.
Congress will then do something to avoid the upcoming fiscal cliff, because no politician wants to be responsible for sending the economy back into a recession. Exactly what that might be depends on the results of the election. Even then, forward progress seems less likely than action to handicap political opponents. None of this zigzagging from left to right is movement down the road.
Is it any wonder, then, that Americans are reluctant to spend money? They dont know how much theyll have to spend in the future. Even if their paychecks remain safe, they can only guess at the bite the federal government will take out of them. Its difficult to be confident that theyll be able to afford a mortgage or car payment, a tuition bill, or even groceries made more costly by the drought.
When consumers are afraid to spend and businesses are afraid to invest, the economy already faltering stalls, with a continued high unemployment rate as the most obvious indicator. Election Day wont provide an instant fix. Allowing or even prompting the country to spiral toward economic paralysis is not a moral strategy for political positioning. Whats best for incumbent candidates is not necessarily whats best for the nation.
This is one of the reasons Americans dont trust their political leaders and dont have faith that the two-party system, now a system of gridlock, is an effective way to govern. The bottom line is that this behavior harms the economy and its smaller participants, who cant influence it in any meaningful way and whose pockets are not plump enough to finance a long vacation while waiting for our representatives to trot back to Washington and do what they were elected to do.


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The requested event could not be found. Use the page below to find upcoming events in your area.
Zero Motorcycles hosts and participates in events around the world. For information about a particular event click on the red marker and then click on the link to the event you are interested in attending. Many of these events offer demo rides.
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2012-02-29 / Obituaries
Christopher Anglum, former Massapequa Park resident, Postal worker
Christopher Anglum grew up in Massapequa and Massapequa Park, attending local schools here as a special needs student. It was a community that he came to love, and that loved him in return, said his sister Monica Stankard of Massapequa.
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Social media could take the top spot
E-mail is not on the way out; its numbers continue to grow, according to the Blue Coat Web Security Report for 2009. But it is not growing nearly as quickly as Twitter and a host of other Web 2.0 collaboration tools. And along with these new tools comes a new generation of exploits to threaten them.
It is no surprise that criminals are taking advantage of new applications and services to deliver malware and extract sensitive information. What is surprising is the amount of change that has occurred in the last year, remarkable even at Internet speeds.
"Social networking was already gaining traction in 2008, but its popularity exploded in 2009," the Blue Coat report said. "Blue Coat Labs saw an increase of over 500 percent in the frequency with which people accessed social networking sites during 2009."
The report cited a Nielsen Co. study showing that 277 million people used e-mail across the United States, Europe, Brazil and Australia in August 2009, a 21 percent increase from the year before. But the number of users on social networking and other community sites jumped 31 percent to 302 million. Social networking increasingly is being used in place of e-mail as a medium for both personal and professional communication and collaboration. Twitter, relatively unknown in 2008, jumped from 2.5 million tweets a day in January 2009 to more than 30 million a day by the end of the year.
These changes, along with an economic recession, have been blamed by USPS for a 13 percent decline in mail volume in fiscal 2009, which cost the USPS nearly $7 billion in revenue. "Electronic media have replaced the letter as the primary means of social and business communication," USPS said in explaining a money-saving proposal that would limit mail delivery to five days a week. "Revenue from First-Class Mail — the Postal Service's longtime bread-and-butter product — continues to decline as the use of electronic message delivery increases."
These shifts are bad news not only for the nation's mail carriers, but also for eager adopters of the latest tools.
"Twitter's popularity brought it to the attention of cyber criminal organizations, which found several ways to manipulate the service into distributing malware and phishing links with enticing, socially engineered messages," Blue Coat reported.
The number and power of devices that can access the Internet is growing rapidly, and the number of applications being created for them is growing even more quickly. Too quickly for any meaningful quality assurance or security.
"The app market as a whole, which is still emerging and largely unregulated, is fertile ground for criminal activity," Blue Coat reported. "For instance, malicious apps disguised as gaming apps have already hit the market. What's worse, many companies sell untested apps in their online stores, leading customers to believe these products are reliable and legitimate."
The result is a strange new world in which devices and applications are moving into our daily lives and into the enterprise at a speed that is leaving network administrators and security experts farther and farther behind. The solution? Caution. Just because everyone is tweeting does not mean that Twitter should be an information channel for your organization -- at least not yet. And be careful about what those tweeters are bringing into your enterprise on their new handheld devices.
About the Author
William Jackson is a Maryland-based freelance writer.
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Sorry, but there may be less here than meets the eye. A lot of businesses use e-mail as their de facto document filing system and likely will remain so for a variety of reasons (chain of events, ease of use). I use Facebook et all, but still receive emails on them in addition to posts. My bet is that "web 2.0" won't replace email so much as it represents a new way of communication in addition to e-mail. Think iPad vs. notebooks.
I support USPS.For family 1000's of miles away, I often still choose to mail a card, or a photographic print, or a CD. Sometime there's a combo pack, including an hand-written ala fountain pen message.Usually such things are spur of the moment, and I have always found the USPS stations staffed by helpful people. Not avatars, but people.Makes those special shipments even more.When I hear of the changes in the USPS marketplace, I think of the Kevin Costner movie, "The Postman". I believe there is a need for such a public service.
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Coal mine safety in new zealand
Following yet another disasterous explosion within an underground coal mine in Westland NewZealand,further protection must be made available to the brave men working at the coal face and elsewhere below and in the mine environment underground. Although state of the art monitoring equipment,sensors,fibre-optic communication with the said high tech equipment,disasters continue; PIKE RIVER COAL MINE is the most recent tragedy which happenned causing the deaths of 29 brave men working at the coal face.The families of these men and the whole mining community is bereaved as indeed is the whole nation. Specially bred Canaries are availiable from Europe and specially designed cages for taking the canaries underground.These birds are highly sensitive to carbon monoxide gas and methane gas which are the main ingredients in asphixiation and explosions in a confined environment. Canaries are not subject to "Murphy's Law" (ANYTHING THAT CAN GO WRONG WILL GO WRONG) These ultra modern sensors ARE subject to the afore said "Murphy's Law" Think carefully before you put your signature on this petition. The RSPCA will indeed oppose this petition as will The Department of Conservation and The Department of Agriculture and Fisheries. SIGN NOW AND HELP SAVE LIVES.


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Trayka lives with her mom in a two bedroom apartment...
My Step Brother
- by mrs_harry_styles_2013
- Rating:
- Published: 27 Feb 2013
- Updated: 21 May 2013
- Status: Complete
Rene'e is from Mooresville, Indiana. She lives there with her dad in a peaceful little neighborhood called Rooker Trace. Rene'e has the best friends a girl could ask for, the perfect house, the perfect life. Until her dad meets someone from Holmes Chapel in the UK and is forced to move there with her and her two kids.
Rene'e finds herself faced with a very awkward situation.
Rene'e finds herself faced with a very awkward situation.
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12th October 2009, 01:47 PM
hey guys on friday I bought some worm tablets for Clara as she needs to be wormed again. She has been dragggin her bottom so I had her anal glands done but she continued to drag it. So when i got home i relised the worm tablets werent tablets but 4 sachets. It said on the back of the pack to be givin to a puppy once a day for 3 days. I mixed it in with just wet food so she would eat it. She ate it friday and saturday so yesterday i mixed the 3rd with dry and wet food she did eat a good bit but not all of it. Last night and this morning she has been draggin her bottom again!:eek: Should i give her the 4th sachet or would it be too much for her to get a worm tablet and give it to her? I also noticed that the powder has been coming out in her urine?? anybody got any advice of what i should do?


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WGBH's Media Access Group makes media accessible to all.
For more than 40 years, the Media Access Group at WGBH has been providing accessible media services to the 36 million Americans who are deaf, hard of hearing, blind, or visually impaired.
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The plan is actually remarkably straightforward. People who've installed Windows 8 preview releases will recall the installation spends a little while setting stuff up in the background after selecting a few user settings. During this part of the setup, Microsoft will play a short animation, explaining to both touch and mouse users how to activate the Charms bar - and that's it.
It's all quite elegant and simple, but it only explains this one tiny little thing of Metro - and yet, there's so much more stuff that's just hidden and hard to discover. I think Microsoft's hope is that by pointing users to one single gesture/location, users will be enticed to explore and discover the rest.
Other than discoverability, I think Metro's major issue is just how volatile it all is. Bringing up the Charms bar or task switcher is one thing, but getting users accustomed to just how easily they are dismissed is going to be a tough task. Current interfaces are relatively persistent, and things don't easily disappear without user interaction. The volatility of Metro's core user interface elements is something that still bothers me - and I've been using Metro every day for months.
Back in '95, this was enough to get users to use the Start menu. I'm very curious to see if this is going to be enough to get users to use Metro.


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25 U.S. Code § 640d–8 - Allotments in severalty to Paiute Indians now located on lands; issue of patents declaring United States as trustee
prev | next
Notwithstanding any other provision of this subchapter, the Secretary is authorized to allot in severalty to individual Paiute Indians, not now members of the Navajo Tribe, who are located within the area described in the Act of June 14, 1934 (48 Stat. 960), and who were located within such area, or are direct descendants of Paiute Indians who were located within such area, on the date of such Act, land in quantities as specified in section 331 [1] of this title, and patents shall be issued to them for such lands having the legal effect and declaring that the United States holds such land in trust for the sole use and benefit of each allottee and, following his death, of his heirs according to the laws of the State of Arizona.
[1] See References in Text note below.
Source(Pub. L. 93–531, § 9,Dec. 22, 1974, 88 Stat. 1716.)
References in Text
Act of June 14, 1934, referred to in text, is act June 14, 1934, ch. 521, 48 Stat. 960, which was not classified to the Code.
Section 331 of this title, referred to in text, was repealed by Pub. L. 106–462, title I, § 106(a)(1),Nov. 7, 2000, 114 Stat. 2007.
LII has no control over and does not endorse any external Internet site that contains links to or references LII.


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Project Description
This GTI (formerly Aerojet Rocketdyne) project will evaluate a novel process for pressurized oxy-combustion in a fluidized bed reactor. The pressurized combustion in oxygen and the recycle of carbon dioxide gas eliminates the presence of nitrogen and other constituents of air, minimizing the generation of pollutants and enabling the economic capture of CO2 gas.
Project Benefits
This project focuses on development of an oxygen-fired pressurized fluidized-bed combustor (Oxy-PFBC). The Oxy-PFBC operates at high pressure and improved efficiency, lowering capital and operating cost, and incorporates limestone injection to facilitate SO2 removal, reducing emission control equipment costs. Specifically, this project will design, build, and test a small-pilot scale Oxy-PFBC combustor to provide data necessary for scale-up.
Contact Information
Click to view Presentations, Papers, and Publications


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Residents are being invited to find out more about plans for a huge solar farm in Duckmanton.
Renewable energy firm RES wants to build about 27,000 solar panels on 30 acres of land at Tom Lane.
The farm would supply power for up to 1,600 households each year.
Members of the public are being urged to attend a public exhibition at Duckmanton Primary School, on West Crescent, Duckmanton, between 3pm and 7pm on Monday, March 24.
Eliot Davies, project manager at RES, said: "We are eager to discuss the proposal with as many local people as possible.
"We will be providing information to help people understand in more detail what we are proposing and why we consider this site to be suitable for solar electricity generation."
The Hertfordshire-based firm will consider feedback from the public before submitted a planning application for the solar farm later this spring.
RES is one of the world's leading independent renewable energy companies.
• What do you think about this plans? Sign in and comment.


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WESTCHESTER COUNTY, N.Y. – A one-car accident early Friday morning in the Bronx just over the Westchester border tied up traffic on Interstate 95 for the rush hour commute.
A report on abclocal.go.com said the accident occurred at 5:30 a.m. on the northbound New England Thruway at Exit 13 in the Eastchester section. Lanes re-opened, but rubbernecking delays were reported.
The report said nine people were rushed to Jacobi Hospital with critical injuries as a Cadillac Escalade slammed head-on into a wall near the exit ramp, the report said. Entrance and exit ramps to the Thruway were closed to investigate the accident.
Click here to sign up for Daily Voice's free daily emails and news alerts.


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The Lord of the Rings (1955 radio series)
The Lord of the Rings was a radio series broadcasted in 1995 and 1956 by the BBC, shortly after the release of The Return of the King. No known recordings of this broadcast are known to have survived, unfortunately.
|Norman Shelley
|Tom Bombadil
|Norman Shelley
Adapted by Terence Tiller.
This adaptation was made while J.R.R. Tolkien was still alive, and he expressed his criticism about the radio series in letters 175 (November 30, 1955), 176 (December 8, 1955) and 177 (same date). At this time, the episodes describing the chapter Many Meetings was apparently the most recently aired.
Tom Bombadil: Considered by Tolkien "dreadful".
Goldberry: She is for some reason portrayed as Bombadil's daughter.
Willowman: He is shown in league with Mordor, rather than just an antagonist of the Hobbits.
Glóin: He was "someone's idea of a German". Tolkien thought he was not too bad, though a bit exaggerated.
After Tolkien's criticism of the series, adapter Terence Tiller corresponded briefly with him. Letters 193 deals primarily on accents, while 194 shows more of Tolkien's criticism of changes made to the story.


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Need a lawyer?
NCAA Texas State Bobcats Mens Gameday Boots Brass 9Qx6qMv2a
for police charges and court matters. Phone BalaMasa Girls Metal Bowknot Buckle Patent Leather Sandals Apricot JGrRo
for care and protection and family matters
Schmitts Grins (Classic Rock/Country) will perform atBlumenhof Winery in Dutzow, MO on Saturday, November 19 from 2-5pm.
Music by Phil Vandel
Special music event featuring Phil's "Bad Habit" CD
Wine Glass Painting Event
$25 pp includes all supplies and instructions to paint your own unique wineglass.
Downstream (Folk Trio) will perform at Blumenhof Winery inDutzow, MO on Sunday, November 20 from 2-5pm.
Marissa Harms (Pop/Country) will perform at Blumenhof Winery in Dutzow, MO onFriday, November 25 from 4-7pm.
Friday Happy Hour is 4-6pm.
34th Candlelight Christmas Walk
Friday December 2nd, 2016 Friday December 9th, 2016 From 5 to 10 p.m.
Picture yourself inside a Norman Rockwell Christmas painting! That's exactly how you'll feel as a corridor of over 1500 glowing luminaries welcomes you to the sights, sounds and smells of 'Christmas yesteryear' in charming Augusta, Missouri.
Please monitor our website (
BalaMasa Womens Multilayer Metal Strap Mule Zipper Frosted PumpsShoes Red clKym
) for the details
A traditional German Christmas market in our heated Sherry House. Crafts, Christmas goodies, carolers, hot soups, mulled wine.
Saturday, 10 a.m. - 5 p.m. and Sunday 10 a.m. - 4 p.m.
Heading to Weston for the Candlelight Homes Tour? Come warm up in Weston Wine Company with a special Hot Chocolate Cupcake and mug of warm, spiced wine. These delectable full-sized cupcakes are only $1.99/each, $10.99 for a 6-pack or $19.99/dozen! We'll be open 'til 7:00 pm both Saturday and Sunday nights. Feel free to call us at (816) 386-2345 to reserve your cupcakes as they're only available while supplies last.(Sunday 12-5pm)
Stuart Johnson (Jazz/Pop Classics) will perform atBlumenhof Winery in Dutzow, MO on Saturday, December 3 from 2-5pm.
Instructor:Angie Carmack


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SOURCE: Sarepta Therapeutics, Inc.
November 26, 2012 08:30 ET
Collaboration Represents Significant Progress in Sarepta's Path to Develop Treatments for Broader DMD Population
Collaboration Represents Significant Progress in Sarepta's Path to Develop Treatments for Broader DMD Population
CAMBRIDGE, MA--(Marketwire - Nov 26, 2012) - Sarepta Therapeutics (NASDAQ: SRPT), a developer of innovative RNA-based therapeutics, announced today a collaboration for the development of an additional exon-skipping drug targeting exon 53, its fourth drug in development, in support of Sarepta's broad-based program for the treatment of Duchenne muscular dystrophy (DMD). Sarepta's collaboration is with University College London's (UCL) scientist, Professor Francesco Muntoni, MD, the Dubowitz Neuromuscular Centre, the Institute of Child Health and other scientists from the EU and US. The EU Health Innovation-1 2012 Collaborative research grant will support certain IND-enabling activities and clinical proof of concept studies for an exon 53-skipping therapeutic. Sarepta recently announced positive results from its extension study of its Phase IIb trial of eteplirsen, its exon 51-skipping therapeutic candidate for the treatment of DMD. Sarepta is also developing other PMO-based exon-skipping drug candidates for exons 45 and 50.
"The recent compelling clinical data on eteplirsen targeting exon 51, which started with our work on the Phase I study in the UK, provides a strong foundation for using Sarepta's technology against exon 53," said Francesco Muntoni, professor of pediatric neurology and head of the Dubowitz Neuromuscular Centre at the UCL Institute of Child Health, London. "We are pleased to be working with Sarepta to bring this exciting exon-skipping therapeutic approach to Europe and the broader DMD population."
This program will be based on Sarepta's advance proprietary RNA-based platform, Phosphorodiamidate Morpholino Oligomers (PMOs), which is a novel backbone chemistry that provides enhanced target tissue specificity, increased potency to allow for more efficient dosing, and greater uptake within a cell to further increase protein production. Targeting exon 53 with this technology will potentially address one of the most prevalent sets of mutations in DMD that are amenable to exon-skipping (deletion of exons 42-52, 45-52, 47-52, 48-52, 49-52, 50-52, or 52) by restoring the cellular machinery's ability to produce a functional dystrophin protein.
"The initiation of this program, along with our other collaborations for exons 45 and 50, continues to advance Sarepta's strategy in pursuing exon-skipping therapeutics for all of the DMD patients who may benefit from this drug technology," said Chris Garabedian, President and CEO of Sarepta Therapeutics. "Our goal of demonstrating that the success of eterplirsen can be reproduced across other exon-skipping targets is a critical step in being able to treat more boys and young men affected with this devastating disease."
About EU Health Innovation-1 2012
The aim of the EU investment in health research is to improve the health of European citizens, to address global health issues and to boost the competitiveness of European health-related industries. Each year the European Commission publishes calls for proposals to which researchers can apply for collaborative research grants.
The European Commission implements a thorough and transparent evaluation process to identify proposals worthy of funding. The process is firmly grounded in the principle of access for all and the codes of fairness, impartiality, confidentiality, efficiency and ethics. For more information please visit http://ec.europa.eu/research/health/index_en.html.
About Dubowitz Neuromuscular Centre and UCL Institute of Child Health
The Dubowitz Neuromuscular Centre (DNC) provides a multidisciplinary service as a leading clinical and research center specializing in neuromuscular disorders affecting individuals in the pediatric age. The DNC provides clinical assessment, diagnostic services, advice on treatment and rehabilitation, and is involved in clinical trials and in basic research focused on understanding the cause of neuromuscular diseases in childhood, and identifying novel therapeutic intervention. Excellence in this field is demonstrated not only by the National Commissioning Group (NCG) status achieved in 2000 to provide a national specialist diagnostic and assessment service for Congenital Muscular Dystrophies and Congenital Myopathies, but also by the designation as a muscle center by the Muscular Dystrophy Campaign.
The DNC is part of the UCL Institute of Child Health and Great Ormond Street NHS Trust and is a member of the recently created MRC Neuromuscular Translational Research Centre at UCL. In addition to the service provided for all pediatric neuromuscular disorders, the DNC is involved with clinical, molecular and cell biological research mostly focused on the genetic basis of congenital muscular dystrophies; on muscle stem cell and on experimental therapies for Duchenne muscular dystrophy. For more information please visit http://www.ucl.ac.uk/ich/research-ich/dubowitz.
About Duchenne Muscular Dystrophy and Eteplirsen
Duchenne muscular dystrophy (DMD) is an X-linked rare, degenerative neuromuscular disorder causing severe, progressive muscle loss and a premature death. One of the most common fatal genetic disorders, DMD affects approximately one in every 3,500 boys worldwide. A devastating and incurable muscle-wasting disease, DMD is associated with specific inborn errors in the gene that codes for dystrophin, a protein that plays a key structural role in muscle fiber function. Progressive muscle weakness eventually spreads to the arms, neck and other areas. Eventually, this progresses to complete paralysis and increasing difficulty in breathing due to respiratory muscle dysfunction requiring ventilatory support, as well as cardiac muscle dysfunction leading to heart failure. The condition is terminal, and death usually occurs before the age of 30.
Eteplirsen is Sarepta's lead drug candidate that is designed to address the underlying cause of DMD by enabling the production of a functional dystrophin protein. Data from clinical studies of eteplirsen in DMD patients have demonstrated a broadly favorable safety and tolerability profile and restoration of dystrophin protein expression. Eteplirsen uses Sarepta's novel phosphorodiamidate morpholino oligomer (PMO)-based chemistry and proprietary exon-skipping technology to skip exon 51 of the dystrophin gene enabling the repair of specific genetic mutations that affect approximately 13 percent of the total DMD population. By skipping exon 51, eteplirsen may restore the gene's ability to make a shorter, but still functional, form of dystrophin from messenger RNA, or mRNA. Promoting the synthesis of a truncated dystrophin protein is intended to improve, stabilize or significantly slow the disease process and prolong and improve the quality of life for patients with DMD.
About Sarepta Therapeutics
Sarepta Therapeutics is focused on developing first-in-class RNA-based therapeutics to improve and save the lives of people affected by serious and life-threatening rare and infectious diseases. The Company's diverse pipeline includes its lead program eteplirsen, for Duchenne muscular dystrophy, as well as potential treatments for some of the world's most lethal infectious diseases. Sarepta aims to build a leading, independent biotech company dedicated to translating its RNA-based science into transformational therapeutics for patients who face significant unmet medical needs. For more information, please visit us at www.sareptatherapeutics.com.
Forward-Looking Statements and Information
In order to provide Sarepta's investors with an understanding of its current results and future prospects, this press release contains statements that are forward-looking. Any statements contained in this press release that are not statements of historical fact may be deemed to be forward-looking statements. Words such as "believes," "anticipates," "plans," "expects," "will," "intends," "potential," "possible" and similar expressions are intended to identify forward-looking statements. These forward-looking statements include statements about the development of eteplirsen and its efficacy, potency and utility in the treatment of DMD and the potential for the creation of novel dystrophin to lead to significant clinical benefit over a longer course of treatment.
These forward-looking statements involve risks and uncertainties, many of which are beyond Sarepta's control. Known risk factors include, among others: clinical trials may not demonstrate the safety and efficacy of eteplirsen and/or Sarepta's antisense-based technology platform; treatment of patients with DMD using eteplirsen over a longer duration may not lead to significant clinical benefit; and any of Sarepta's drug candidates, including eteplirsen, may fail in development, may not receive required regulatory approvals, or be delayed to a point where they do not become commercially viable.
Any of the foregoing risks could materially and adversely affect Sarepta's business, results of operations and the trading price of Sarepta's common stock. For a detailed description of risks and uncertainties Sarepta faces, you are encouraged to review the Company's filings with the Securities and Exchange Commission. Sarepta does not undertake any obligation to publicly update its forward-looking statements based on events or circumstances after the date hereof.
Sarepta Media and Investor Contact:
Erin Cox 425.354.5140Email Contact
Sarepta Media and Investor Contact:
Erin Cox 425.354.5140Email Contact
See all RSS Newsfeeds


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I plan to get a Sigma SD14, any advise on what lens i should get? Am thinking of something like the Nikon 18-200mm f/3.5-5.6G ED IF AF-S DX VR Wide Angle Telephoto Zoom.
Thank you very much.
Last edited by Nautilus; 06-03-2008 at 06:19 PM.
Oh, found this Sigma Lens, Sigma Zoom Super Wide Angle 18-200mm f/3.5-6.3 DC OS (Optical Stabilizer) Lens (Nikon F).
Any comments on this lense?
I like to take pictures of nature scenery, animals from a distance and colourful buildings.
Thank you.
I use the Sigma 18-200mm on my Canon. Its not a brilliant lens but gets work done for me as a single lens solution though if you don't mind changing lens then I'd ask you to look at some other lens.
Nikon EM, Series E lenses 50mm f1.8|28mm f1.8|100mm f2.8, Sigma 80-200mm f4.5-5.6
Minolta Riva 100AF, Sinpo PQ-3, Olympus mju-III wide 100, Yashica 635
Sony cybershot W90, cybershot T90
Canon A720i|400D|7D|5DMKII|85mm f1.8|24-105mm f4|135mm f2|40mm f2.8|430EX II*2|BG-E3|BG-E7
Sigma 24mm f1.8|50mm f2.8|105mm f2.8 Samyang 8mm fisheye
Try the new Sigma 50/1.4. This is an excellent lens. But obviously no zoom. The 18-200 OS is very good, but not in the league of the 50/1.4
I am new in this forum. I have Sigma SD14 (with 18-200mm lens) for about 9 months and I am happy with it. But I need to have better pictures (mainly sharpness and CA) for indoor pics. I am planning to add a prime lens and considering 50mm f/1.4 and 30mm f/1.4. Can you give me some suggestions which is is better OR if I can use other lens (from other brand(s) that fits SD14 without adopter)?
Thank you all in advance. Have a great Christmas and HAPPY NEW YEAR.
Forum Rules


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It's important to retain a touch of nostalgia when updating your holiday home.
Nature's chorus was a soporific song to a young Shelleece Stanaway who lay play-weary in the top bunk at her parents' Paihia bach listening to the buzz of cicadas and the familiar call of the morepork.
The fibrolite home on a hill overlooking the sea out towards Russell was built in the 1950s by her grandfather. "We'd hibernate there annually for three to four weeks," says Shelleece.
Paihia is now a bustling tourist town, but back in the day it was a sleepy spot. "My elder brother and I would row out to "Rat Island" just offshore and Mum could call out to us from the deck or wave a towel when lunch was ready."
Though the place was very simple, Shelleece's holiday memories are an indelible reference for this interior designer whose ideas on decorating baches stem from those days of summer freedom.
Here, Shelleece shares her thoughts on bach decor, on what we can take from the past and how to update it:
Then: Our bach was originally painted dark brown with a white corrugated roof, then it went white and recently it has been updated with a coat of Resene Tea.
Now: I love the serenity of muted colours that keep things bright and airy. Because Kiwiana baches are usually small, use one colour throughout. Take your cue from the surroundings, the grey-blue of the sea on a cloudy day, for instance. I like to keep walls neutral. Karen Walker for Resene Wan White is nice or try a lovely soft colour such as Resene Clouded Blue. Accessorise with stronger shots - turquoise is my favourite. But don't be afraid to express yourself, either. Weatherboards look good dressed in retro-inspired ice-cream pinks, blues and Depression green, like those gorgeous rustic baches on Rangitoto Island.
Then: We collected shells and mum displayed them on top of the chest of drawers, or we made wind chimes with them using old twine. Mum had a basket and she never went anywhere without it - to the beach, on tramps through the bush, to the dairy - and we often came home with the treasures we'd picked up while walking.
Now: it's a delightful idea to use found objects to decorate with. Forage for flowers and foliage so you can bring the outdoors in every day. Get children involved in adding to the decor. If they find curious keepsakes, put them on a shelf. If they bring home feathers, display them in a container.
Then: Dad had a plumbed-in bench with a sink attached to one of the outside walls.
Now: Because space inside can be limited, consider the garden another room. Use it at will. An outside shower is a necessity. And the official kitchen should be reserved for bad-weather-only food preparation. If the budget stretches to it, shield the deck from prevailing winds with those clear drop-down plastic sides. Shade sails are a practical, affordable option that you can take down when not in residence. Get them in cream or white so they don't fade.
Then: our deck was really just the top of a big concrete water tank. We'd lounge around on old stretchers under one of those floral umbrellas in greens and blues - with compulsory tassels. We also had a swing seat where you could sway and wile away the time.
Now: A hammock chair or swing seat made from rattan (Citta has a nice one), is the new version of that old thing. Consider using upholstery fabric, pretreated with waterproofing and UV protection for your indoor furniture too. That way, if need be, those chairs can be taken outdoors when more unexpected guests drop by. These fabrics were once only available in solid colours but now you get some fabulous funky prints. Although they're tough enough to be outdoors, they're also amazingly soft in texture, not like the plasticky stuff of old that made your thighs sweat! Ottomans are a bach must have. They can be used as tables, as extra seating and some even contain storage. But mainly they're there to encourage you to put your feet up. Check out Homage's gorgeous new knitted ottomans in fabulous colours, they're not as practical as ottomans upholstered in leather which you can wipe them clean, but great fun. I like round ottomans because having furniture with corners in a small space where kids are running around is problematic.
Then: We had no window treatments because our place was so private - but we did have lots of louvres. Now: Keep window treatments simple and unadorned. Use drapes that are made from natural fibres, such as linen and hemp (David Trubridge has a new design, Traces, for Hemptech). Stick to neutral colours as others will fade really quickly. There are many beautiful sheers around that add a wonderful sense of lightness to the bach.
Then: Mum kept a bucket of water at the door so we didn't trail sand into the house. There was a nasty red-and-brown axminster-style carpet in the bedrooms. Although axminster is coming back into style now, those particular colours will never be fashionable again, I hope.
Now: Wooden floors are the most practical but tiled floors are another option. Warm them up with rugs. I like whitewashed or paler timbers on the floor as they lend a feeling of serenity. Keep as much as possible off the floor. Use hooks, hooks and more hooks for towels, beach bags, hats.
Then: My mother always seemed to be preparing food on our rather small kitchen bench, be it sandwiches all lined up with delicious fillings for our day trips on the yacht or preparing salads for our barbecue dinners.
Now: Consider adding to your bench space by using a butcher's block or industrial style table on castors. That way you can roll it outside should it be needed next to the barbecue, too. The Boiler Room in Kingsland is a great place to look for these.
Then: My father is very much a hunter/gatherer and so I have grown up with taxidermy - our flying ducks on the wall were the real thing! I also recall a couple of Tretchikoff prints and remember thinking as a child that those portraits of ladies draped in a tree were rather voluptuous.
Now: Finally you've found somewhere to bring your old bone-handled cutlery, mismatched English crockery, decanter set and your collection of old wooden boxes. Make playfulness an integral part of your decor. Mismatched objects from every decade are almost de rigueur. And though photos in your city home should be confined to the bedroom, take every opportunity to get them on public display - they'll become a record of good times and bad fashion. A magnetic photo rope is cheaper than frames or use a corkboard painted white and pin them to that. Or create your own memory mobile using wire and mini pegs (kikkiK have some) to clip on the photos.


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(15 Days - Departs Daily on a Private Basis)
Dublin, Kilkenny, Cork, Kenmare, Killarney, Co. Clare (Dromoland Castle), Co. Mayo (Ashford Castle)
This private tour focuses on Ireland's unique culture, cuisine and crafts. It includes beautiful landscapes, places rich in Irish history, and opportunities for insider, hands-on access to Ireland's artisans and cultural experts.
Begin in Dublin, the capital of Ireland and the perfect starting point for an overview of the country's long and storied history. During touring with your private guide and driver, marvel at the iconic Book of Kells and the Long Room in the Old Library at Trinity College, and tour St. Patrick's Cathedral, one of the most important churches in Ireland. Walk in the footsteps of Irish literary giants such as James Joyce and Oscar Wilde in Georgian Dublin, a neighborhood of well-preserved architecture set around leafy St. Stephen's Green. Take a culinary walking tour to sample treats at top local food markets and shops. Enjoy a private tour of the Old Jameson Distillery, followed by a private tasting of the distillery's finest products. Perhaps opt for high tea with pastries inspired by Ireland's literary and artistic masters. Depending on interests, stroll through the Temple Bar entertainment district, browse the upscale shops on Grafton Street, perhaps cross the River Liffey to walk along historic O'Connell Street, or stop by the Guinness Storehouse and opt for a pint in the on-site bar, which has views over the rooftops of Dublin. Additional touring options in Dublin include the National Museum of Ireland – Archaeology, Kilmainham Gaol and Chester Beatty Library. Upon request, Artisans of Leisure can also arrange theater tickets and reservations at Dublin's best restaurants for contemporary Irish cuisine.
En route to Kilkenny, enjoy private touring in idyllic County Wicklow. Tour the stunning gardens at Powerscourt House and Gardens. Pass through verdant farmland and rolling hills to Glendalough, a beautiful glacial valley with the ruins of an ancient monastery set among lakes. Also tour historic Avoca Mill, where some of Ireland's finest and most colorful textiles have been produced for centuries.
Continue to Kilkenny, an atmospheric riverside town of medieval streets and the center of Ireland's burgeoning local crafts movement. Tour Kilkenny Castle, a popular landmark from the 13th century. Also see St. Canice's Cathedral—a noted Gothic church—and the ancient Round Tower that sits among the Celtic cross tombstones in its churchyard. Also visit Kilkenny Design Centre, a showcase of locally produced crafts such as textiles, ceramics, furniture, glass, jewelry and leather goods. This afternoon, visit one of Ireland's most renowned cheesemakers for a private cheesemaking demonstration and tasting. Additional options include visiting the workshop of local glass artisans, seeing the ruins of Jerpoint Abbey or Kells Priory, or shopping for crystal in Waterford.
Continue with your private driver-guide to County Cork, stopping en route at the imposing Rock of Cashel, an important hilltop religious complex dating from the Middle Ages. Learn about the roots of Irish cuisine with a private cooking class at a renowned cooking school. In the city of Cork, tour the excellent English Market, where purveyors offer fresh local produce, meat, fish and baked goods. Visit nearby Kinsale, a picturesque fishing village known as one of Ireland's top culinary destinations due to its fresh seafood and highly regarded restaurants. Another option is the port town of Cobh, the departure point for over 2.5 million Irish immigrants and the final port of call of the R.M.S. Titanic.
Next, drive deep into the bucolic countryside of rural West Cork. Explore charming seaside villages; stop by artisanal food producers to sample local specialties such as cheese and black pudding; and visit historic Bantry House & Garden, a privately owned estate on park-like grounds overlooking spectacular Bantry Bay.
Continue to County Kerry and Kenmare, a colorful village with a prehistoric stone circle and access to the beautiful peninsulas that define southwest Ireland. Enjoy a scenic drive around the breathtaking Beara Peninsula, a wild landscape of jagged coastlines, craggy mountains and sparkling lakes.
En route to Killarney, travel through the heart of Killarney National Park to Muckross House. Tour the estate and grounds, and perhaps also visit Muckross Traditional Farms, an open-air museum, to learn to bake traditional brown bread. Next, take a horse-drawn jaunting car ride through the woods to Ross Castle, and then a private boat ride among the islands and rocky outcroppings of Lough Leane.
One day, enjoy a private excursion around the spectacular Dingle Peninsula, taking in awe-inspiring views of the coastline and mountains. Along the way, explore ancient ring forts and other prehistoric sites, wander through quaint seaside towns, and visit shops featuring crafts created by the many local artisans. Another option is to explore the Ring of Kerry, driving the dramatic route atop the sea cliffs and through the mountains of the Iveragh Peninsula.
Pass through Adare, a postcard-perfect village of thatched-roof houses and shops, en route to Bunratty Castle. Tour the impressive 15th-century fortress and neighboring Bunratty Folk Park, a charming recreation of a 19th-century Irish village. Continue to historic Dromoland Castle, a luxurious destination hotel and resort on expansive grounds. During leisure time, enjoy on-site activities such as golf, fishing, hiking, horseback riding, falconry, tennis, archery and more. Opt to tour the kitchen garden with the hotel's head gardener to select fresh produce for dinner. Or, fish for trout or perch on Dromoland Lough. Alternatively, opt to enjoy dinner in a local village famous for traditional Irish music.
En route to Ashford Castle, explore the country charm and geological wonders of County Clare. Walk along the tops of the dramatic Cliffs of Moher, which rise hundreds of feet above the sea. Explore the eerie Burren, a rocky karst landscape punctuated by ancient forts, tombs and other archaeological sites. Pass through picturesque villages with brightly colored houses and shops. Stop at a local smokehouse famous for smoked Irish salmon, and enjoy lunch at a nearby pub. Continue to Ashford Castle, a historic lakefront castle hotel and resort that's a wonderful place to experience Irish culture and cuisine. During leisure time, enjoy activities on the surrounding estate, such as golf, fishing, horseback riding, falconry, kayaking and more.
One day, enjoy a private excursion to Connemara National Park, a rugged landscape of mountains, moors and bogs. Along the way, pass through tiny villages, admire views of the sea, and visit Kylemore Abbey, a beautiful stone building and gardens set on the edge of a lake.
|Itinerary Overview


text: Don't let a little bit of water and wet weather keep you out of the woods. Shop Camo Rain Gear and Waterproof Clothing from Sportsman's Guide is sure to keep you dry and comfortable no matter the size of the storm. Rain won't stop you from abandoning your mission in the woods. Choose from top brands you trust and at the lowest prices...guaranteed!


text:
11 U.S. Code § 1323 - Modification of plan before confirmation
§ 1323.
Modification of plan before confirmation
The debtor may modify the plan at any time before confirmation, but may not modify the plan so that the plan as modified fails to meet the requirements of section 1322 of this title.
After the debtor files a modification under this section, the plan as modified becomes the plan.
Any holder of a secured claim that has accepted or rejected the plan is deemed to have accepted or rejected, as the case may be, the plan as modified, unless the modification provides for a change in the rights of such holder from what such rights were under the plan before modification, and such holder changes such holder's previous acceptance or rejection.
(Pub. L. 95–598, Nov. 6, 1978, 92 Stat. 2649.)
Historical and Revision Notes
senate report no. 95–989
The debtor is permitted to modify the plan before confirmation without court approval so long as the modified plan, which becomes the plan on filing, complies with the requirements of section 1322.
The original acceptance or rejection of a plan by the holder of a secured claim remains binding unless the modified plan changes the rights of the holder and the holder withdraws or alters its earlier acceptance or rejection.
LII has no control over and does not endorse any external Internet site that contains links to or references LII.


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There's one thing that almost all Medicaid patients in South Carolina have in common.
It's not that they're lazy, unmotivated to find work, or that they lie about their income to qualify for free health care.
It's that they're poor.
But complaints leveled against Medicaid beneficiaries and the system itself aren't new.
On the 1976 campaign trail, Ronald Reagan made frequent reference to a Chicago "welfare queen" with a Medicaid card, milking the system for benefits she didn't deserve. Two years ago, Mississippi Gov. Haley Barbour accused Medicaid patients of picking up prescriptions through drugstore drive-thrus in their BMWs. During the 2011 legislative session, S.C. Rep. Kevin Bryant, R-Anderson, called the program a "$100,000 Mercedes" hand-out and said it encouraged a culture of dependency.
A report released by South Carolina's Department of Health and Human Services this month shows health care providers are not immune from stereotyping their poorest patients, either.
"I got tired of seeing my patients rolling up in nicer cars than I drove … to get their free work done," said Brice Elvington, the office manager of Florence Pediatric Dentistry, who also compared Medicaid benefits to free fast food in the report.
"Our analogy is when Chick-fil-A has a 'free chicken sandwich day,' they have the supplies and resources to give out free chicken sandwiches set aside for that particular day," he said. "If you don't show up, you can't go back a week later and demand your free chicken sandwich because you failed to show up on the correct day."
Sharp comments like these included in the report are indicative of the frustration some health care providers have with the low-income insurance program and whether it should grow.
Next year, the country is braced for the largest Medicaid expansion since the entitlement program was established in 1965. The Affordable Care Act will allow states to expand Medicaid eligibility to any resident making up to 138 percent of the federal poverty level, but the South Carolina General Assembly voted this year not to participate, even though the federal government offered to foot 100 percent of the bill through 2017.
"They need to fix the system the way it is now before trying to make it bigger," Elvington said in a phone interview. "I think a lot of providers are frustrated with the way things are now."
Medicaid patients once made up more than 40 percent of Florence Pediatric Dentistry's client list, but the practice no longer accepts Medicaid because those patients frequently missed appointments and because the Medicaid agency reimbursed the office poorly for its services, Elvington said.
Reimbursement rates for Medicaid patients are generally lower than reimbursement rates for patients with private insurance. That means dentists, doctors and hospitals tend to make more money from patients with private insurance plans than those with Medicaid cards.
"We've voiced a lot of concerns to the people that handle the dental side of it and they would always say things are getting worked on but they never would so we said we can't continue," Elvington said.
Florence Pediatric Dentistry may have dropped out of the Medicaid program, but the number of health care providers registered to participate is growing in South Carolina.
In 2012, 51,166 providers were enrolled to accept Medicaid patients, up from 49,105 in 2011 and 46,502 in 2010, according to the state's Medicaid agency.
Since July 2012, more than 200 new Medicaid patient fraud cases were reported to the S.C. Attorney General's office, but data from the S.C. Department of Health and Human Services shows that health care providers are guilty of it, too.
In 2012, the department opened 67 new provider fraud cases. It also keeps a running list of 555 health care providers in South Carolina that are excluded from participating in the Medicaid system mainly because of past fraud cases, but also because of revoked licenses, financial felonies and patient abuse.
"I definitely don't think fraud is a rampant thing in Medicaid in general. I don't think it's become a huge issue where we're getting an exorbitant amount of cases," said Michael Collisi, director of HHS's Pursuits of Excellence team. "It's a very small portion of the public out there."
More than 1 million South Carolina residents hold Medicaid cards and more than half of those are children.
Collisi facilitated a series of Medicaid meetings across the state this year, which were intended to help the department identify regulations that make doing business in South Carolina harder.
He said the feedback they collected in the final report was mainly constructive, but there were providers who attended the meetings only to complain.
"There's always somebody who has angst against the program," Collisi said.
Twenty-seven people attended the three meetings in Florence, North Charleston and Spartanburg.
Dr. Greg Tarasidis, an ear, nose and throat physician based in Greenwood, who did not attend the Medicaid meetings, said that doctors are rightly critical of the Medicaid system, but that doesn't mean they are prejudiced against poor patients.
"On a frustrated day, you may get that perception. That's not what any of us want to be focused on, by any means," said Tarasidis, who represents South Carolina for the American Medical Association.
"Doctors are obviously professional. We take care of people no matter what, for the most part. Unfortunately, medicine has become … more than just that. We still have four walls and roof and bills to pay just like any other small business, so it becomes a business."
Tarasidis said these concerns are widespread among providers, and more doctors will likely drop out if the Medicaid system doesn't improve.
But anxiety about profit margins doesn't fully explain why Medicaid patients are treated differently than others, said Maya Rockeymoore, president of Global Policy Solutions, a national health care consulting firm.
"There are studies that show — and it tends to break down by class and race — people of color and low income get worse treatment in the health care system," Rockeymoore said. "It's a sad statement about the lack of sensitivity that some of our health care providers have."


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Randall Wallace
Greg Kinnear
Kelly Reilly
Connor Corum
Heaven Is for Real (PG)
Drama 100 min. April 16, 2014
Kinnear's preacher dad, one of those Dockers-sporting new-gospel ministers most comfortable in churches that look like refurbished carpet stores, spends much of the film agonizing over whether or not to believe that young Colton got a tour of the afterlife conducted by Jesus himself. It's the kid's knowledge of a miscarriage that finally convinces the family that the story is true, and that it must be shared with the world. (The family's financial travails prove a key plot point, too, but it's hard to invest in the bill-paying drama of characters based on real people who sold their story to the movies.)
Whatever you believe, if even the kid's parents couldn't take it on faith until given extraordinary evidence, it seems unfair to ask the rest of us to just accept their word for it.
Randall Wallace Greg Kinnear, Kelly Reilly, Connor Corum Todd Burpo Sony Pictures


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Mayor calls for community effort to continue Nashua's growthBy KIMBERLY HOUGHTON
Union Leader Correspondent
February 18. 2014 10:19PM
NASHUA — The Gate City has countless assets and unique opportunities to offer, but the community must work together to be Nashua's greatest cheerleader, according to Mayor Donnalee Lozeau.
"We have an obligation to maintain Nashua as the attractive growth center for New England it has become," Lozeau said during her annual State of the City address on Tuesday, noting the city's recent branding campaign provides an ideal platform to showcase Nashua to the rest of the world.
The new tagline for the city — Dare to Begin — will support ongoing development, invite growth within the community, influence and support local initiatives and encourage people to follow their dreams, she said.
In an unusual act, Lozeau opted to pre-record her State of the City speech and then air it on the city's cable television channel after the snow forced Tuesday's scheduled meeting with the Board of Aldermen to be postponed. Today, she will address the Greater Nashua Chamber of Commerce with her annual update.
"I believe we all are committed to supporting a climate for families to thrive, children to learn, businesses to succeed and visitors to enjoy," said Lozeau. "We must work together to be our city's greatest cheerleaders."
And there is much to cheer about, according to Lozeau's speech, which provided a shoutout to SkyVenture, the nation's largest standing wave stream machine that recently opened in Nashua. She also mentioned Thomas More College of Liberal Arts, which will soon expand from Merrimack to Nashua with the purchase of an historic building on Concord Street.
The expansion of the Nashua Riverwalk, the completion of the Jackson Falls Dam crest gate project, the initial construction phase of the Broad Street Parkway and the ongoing downtown improvement projects were also highlighted by the mayor.
Part of the downtown revisions include a stronger police presence along Main Street and surrounding roads, according to Lozeau, who announced a new plan that has been developed to create a permanent police presence downtown during first and second shifts.
Existing office space in the two downtown parking garages will be utilized by police as needed, according to Lozeau, who thanked Police Chief John Seusing for his efforts in amending the staffing to make the goal feasible.
The city's financial status was also one of Lozeau's topics on Tuesday as she noted that the city recently sold $21 million in bonds at an interest rate of 2.43 percent — the lowest the city has experienced in four decades.
"In addition to obtaining the best financing on new loans, the city was able to refinance 13 loans through the state Department of Environmental Services. New Hampshire was the first state in New England to offer this option, and Nashua was the first community in New Hampshire to accomplish it," she said.
Although budget challenges remain, Lozeau maintained that those concerns are being addressed. With rising employee costs and recent revenue declines, she said rating agencies are still citing the city's financial management as strong, particularly in light of recent labor agreements, cost-cutting measures and moderate annual tax levy increases.
For the second year in a row, Lozeau called out three city police unions — the supervisors, patrolmen and communications workers — for failing to reach new contracts that contain the same health care and wage provisions that other city union employees accepted months or years ago.
Lozeau said she remains optimistic that the contracts will be resolved soon with retroactive health insurance costs.
She mentioned several local organizations that have contributed in positive ways to improve the Gate City, including the Mine Falls Park Advisory Committee, the Nashua D.O.G. group and city schools for their increased participation in advance placement courses.
"We have so much going on in this community. There is so much for us to accomplish, so many possibilities," said Lozeau. Some of those possibilities are passenger rail, mixed-use development near the Nashua and Merrimack rivers and a new Exit 36 south, she explained.
Those future successes depend on finding common ground, Lozeau said, explaining it is OK to have philosophical differences and still reach a consensus through thoughtful debate and factual understanding.


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Components enable designers to create reusable Instances of UI elements, manage state and can keep your designs more consistent and manageable. When the master component is updated, the instances update automatically.
Component instances can be nested inside master components. This allows for small, detailed components to be combined with others into larger, more complex interfaces while maintaining granular control over each individual component that syncs between instances.
Inheritance is defined on a per-property basis so designers don't need to create individual components for each state.
Properties that affect the layout of child layers are not overridable on instances, allowing you to maintain a stricter level of consistency with less effort.
Examples of these properties include:
In addition, you cannot add, remove, or reorder layers within instances of components.
Other properties are able to be overridden and allow designers to create variations on the original component to represent state and data while maintaining overall consistency within an interface.
Select any layer, group, or frame and click the component icon in the toolbar, or use the
Option + Command + K
shortcut to convert your selection into a component.
It's not possible to duplicate a component in a single file. When you duplicate a component in a file it will always create an instance of the original component.
However, when you copy a component from file A and paste it into file B, you will have a fully functioning component in file B.
There are a few way to create an instance of a component. First, select the original component and then:
When selecting an instance, right-click and select Go to Master Component . The viewport will snap to the original component's location and the component will be selected.
When the instance is selected, there's also a shortcut just under the Instances section in the Properties Panel .
The Reset Instance icon appears in the toolbar when:
In the example above, the original component (Play Button - Master) is red. Two instances were made and fill overrides were made; one green and one blue.
When either instance is selected the option to Reset Instance appears. This allows you to revert selected instances to its original properties and reconnect its inheritance to the original component. After you Reset Instance , changes made to the master component will again be propagated to the instances.
This also works for any selected layer in the instance.
In the example above, we have the text layer of the blue instance selected. We have overridden the original PLAY text in this instance with bold and italic . With the text layer selected we can Reset Instance .
Medications can only be prescribed by a licensed medical professionals (such as yourphysician or a psychiatrist), who would ideally work together with your therapist to develop a treatment plan.
BUSCEMI Woman Embellished Croceffect Patentleather Hightop Sneakers Size 38 ym8V8BX
Taken together, ERP and medication are considered the "first-line" treatments for OCD. In other words, START HERE! About 70% of people will benefit from ERP and/or medication for their OCD.
[youtube https://www.youtube.com/watch?v=AQNsjMtMFO4]
Yes. If you or a loved one has tried traditional outpatient therapy and would like to try a more intensive level of care, there are options. The IOCDF keeps a Resource Directory of intensive treatment centers, specialty outpatient clinics, and therapist who provide these various levels of services for OCD. The following lists therapy options from least intensive to most intensive:Resource Directory Traditional Outpatient Intensive Outpatient Day Program Partial Hospitalization Residential Inpatient
[youtube https://www.youtube.com/watch?v=nj-4XPoDAdg]
Other recommendations from the APAPractice Guideline, 1 cite research showing that ERP delivered in a group format , as well as ERP therapy delivered via videoconferencing (teletherapy) , might be effective. Also, there is some promising new research showing that Acceptance and Commitment Therapy may be helpful for OCD. You can search for any of these treatment types in the Resource Directory .group format videoconferencing (teletherapy) Acceptance and Commitment Therapy
OCD treatment can be difficult, and requires a lot of courage and determination. Having a support network to talk to during treatment can make all the difference. Consider accessing a support group in your area. Click here to learn more about support groups.support group
OCD can be a family affair. Read more here about the impact on families and what family members can do.
When severe OCD proves resistant to standard forms of treatment, there are other options available . However, it should be noted that all of the following procedures are still currently being researched. While there is evidence to suggest that they could potentially be helpful in reducing OCD symptoms, they are not concretely proven to do so. These should be utilized as a last resort when all of the evidence-based treatment methods for OCD (outlined above) have already been accessed:. However, it should be noted that all of the following procedures are still currently being researched. While there is evidence to suggest that they could potentially be helpful in reducing OCD symptoms, they are not concretely proven to do so. These should be utilized as a last resort when all of the evidence-based treatment methods for OCD (outlined above) have already been accessed:
Garnett and Christidis "contend that the scientific community's failure to govern taxonomy threatens the effectiveness of global efforts to halt biodiversity loss, damages the credibility of science, and is expensive to society." We disagree.
The authors claim that species-splitting provides an incentive to trophy hunters to target small populations, affects biodiversity tallies in ways that negatively impact conservation, and results in inordinately higher funding to oversplit taxonomic groups; but they provide no evidence to support these claims. If hunters target endangered species, then such societal developments should be challenged, rather than used as justification for changing the way in which science is conducted. They cite data in Evans et al. [ 20 ] to imply that different taxonomic approaches between birds and mammals could lead to disproportionate funding relative to genetic diversity, when in fact those data (Figure 6 therein) show that the number of species in a group is not correlated with funding (e.g., fishes comprise 11% of species protected under the United States Endangered Species Act but receive 61% of government funding).
How does taxonomic instability affect conservation? Morrison et al. [ 21 ] "found that changes in taxonomy do not have consistent and predictable impacts on conservation"; they also found that "splitting taxa may tend to increase protection, and name changes may have the least effect where they concern charismatic organisms." In African ungulates, Gippoliti et al. [ 22 ] describe cases where conservation management based on the Biological Species Concept overlooks evolutionarily significant units (recognized with the Phylogenetic Species Concept), with negative consequences. The splitting of legally protected taxa may result in species not being included by name in conservation legislation or regulations, thereby losing legal protection. However, well-crafted legislation includes mechanisms to extend protection despite taxonomic changes; initiatives such as Convention on International Trade in Endangered Species (CITES) and the International Union for Conservation of Nature (IUCN) specialist groups already link taxonomy and its changes with conservation [ 23 ]. Garnett and Christidis assert that taxonomic instability negatively affects conservation. However, artificial stability arising from insufficient taxonomic work can be particularly detrimental to conservation, causing mistargeting of conservation funding by misrepresentation of population size and distribution with the flow-on effects to conservation status [ 11 , 24 , 25 ].
The proposal by Garnett and Christidis for the International Union of Biological Sciences (IUBS) to create a process that "restrict[s] the freedom of taxonomic action" is not only flawed in terms of scientific integrity (as outlined above) but is also untenable in practice. Nomenclature regulates how names are used to communicate taxonomic hypotheses and is governed by rules (Codes) to ensure the least possible degree of ambiguity in the application of names. The relationship between taxonomy and nomenclature is illustrated in Fig 1 . These Codes have been and continue to be refined into complex and intricate legal systems (the International Code of Zoological Nomenclature consists of 90 articles with more than 600 subsections). A system that endeavors to impose similar controls over taxon concepts would likely be vastly more complex than, and in conflict with, the Codes. It is for good reason that the major Codes explicitly avoid interfering with taxonomic freedom.


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December 2010 Explores research findings on the value of motivational incentives to promote and reinforce abstinence from substances of abuse and encourage healthy behaviors.
March 2011
Considers the potential role of physical activity on substance abuse prevention and describes some of the research that has been conducted on this emerging area of addiction science.
July 2011 Reports on NIDA's research priorities—drug abuse and addiction prevention, treatment, and HIV/AIDS—which will remain consistent during these challenging budget times.
November 2011 NIDA Director Dr. Nora D. Volkow summarizes instances where discoveries with broad implications for human health arose from scientists seeking answers to addiction problems.
December 2011 Understanding and responding to drug abuse among America's aging population becomes more urgent as a growing percentage of baby boomers enter the over-50 age bracket.
April 2012 Dr. Volkow discusses NIDA's efforts to develop effective antismoking treatments for populations with persistently high rates of smoking, such as people with psychiatric disorders, high school dropouts, and Native Americans.
July 2012 NIDA researchers have developed a computer program that motivates and encourages treatment-seeking when an individual is in a primary care physician's waiting room. Users of the program, called Video Doctor, enter information on a portable device and receive feedback about health risks related to their drug abuse, along with advice, immediately prior to seeing their physician.
February 2013 Despite the advances in treatment and prevention, roughly 50,000 new HIV infections still occur annually in the Nation. Research, in large part supported by NIDA, has produced a strategy to address this circumstance and break the epidemiological impasse: seek out HIV-infected individuals, particularly those in "hard-to-reach" groups that have minimal contact with the health care system; offer them HIV testing and treatment; and provide support to help them stay in treatment.


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NEW YORK (AP) — Rachael Ray is multitasking.
The author and Emmy-winning chef is getting ready for next month's South by Southwest Festival in Austin, Texas, where she again will be hosting all-day music performances, with more than a dozen bands. One of those bands, The Cringe, is led by her husband, John Cusimano.
The food, of course, will be provided by Ray.
"It's like my Christmas," Ray said during a telephone interview Thursday from her home in upstate New York. "It's a marriage of my love for music and my love for food, in a city that I love."
On Thursday, she also announced the first two releases on her Rachael Ray Books imprint with Atria Books. The books, both out this fall, are Heather Bertinetti's "Fake and Bake" and Associated Press food editor J.M. Hirsch's "Beating the Lunch Box Blues." Atria is an imprint of Simon & Schuster.
"I like supporting people who believe that the quality of life doesn't have anything to do with how much money you have in the bank," she said. "Everybody should be able to afford great food, and that's what I want the imprint to be about."


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Follow RFF News on your cell phone. Text follow rff to 40404 you will receive txt messages with RFF News
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Pet peeve about your teammate: I dont like when Rob farts in public.
Quote from: georgiapeach on August 29, 2012, 09:18:18 AMPet peeve about your teammate: I dont like when Rob farts in public.
Dave & Kelly, anyone?
Speculation: I don't think they have a good chance of winning, but they could be good underdogs that can run a few legs.
Some of you might not like them but, Rob: You know what we got?Phil: You got heart?Rob: That's right Phil.Phil: and how big is your heart?Rob: Well it must be 300 pounds.
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CANNES, France (AP) — Josh Charles and Rosario Dawson were among the luminaries at the annual Heart Fund Charity Ball, but the real VIPs may have been the doctors.
Cardiologists mixed with celebrities at Wednesday's event, designed to raise funds and awareness for Heart Fund, which is dedicated to providing heart care to impoverished children around the world. Heart surgeons donate their services to perform operations for some of the neediest children.
Dr. David Luu, who started the organization, said it comes to the Cannes Film Festival each year to have stars shine a light on the work they do.
"It's not all about the celebrities, it's more than that," he said at the event. "We have surgeon skills in our hand, but we don't have the voices. We need the voice, we need a speaker, and we think cinema is one of the most important media to broadcast messages."
The evening's entertainment included actor Gary Dourdan, who performed songs on acoustic guitar. But the highlight of the evening came when Jack Penrod, the founder of Nikki Beach Worldwide with beach clubs, restaurants and hotels, and his wife Lucia donated 100,000 euros to the organization so it can purchase a "Heart Bus," a mobile hospital to screen and treat needy children.
— By Nekesa Mumbi Moody, http://www.twitter.com/nekesamumbi


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The mathematics department at Roanoke College makes a firm commitment to incorporating Mathematica throughout its curriculum. Associate professor Chris Lee says it's paying off in a big way, and that the key to success is having students use Mathematica from day one.
"The students are a lot more invested in the process," says Lee. "They retain the concepts better because I think using Mathematica all the way through, they're becoming very comfortable with the software and appreciating how it can help them visualize what's going on with their solutions and problems."


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ATLANTA (AP) — City leaders in Atlanta and organizers of an annual marathon that draws 60,000 runners to the city say they will be taking enhanced security measures in the wake of the April 15 Boston marathon bombings.
Mayor Kasim Reed said Monday that details are still being worked out but participants and spectators at the very least can expect to see more police officers at the AJC Peachtree Road Race on July 4. Reed says authorities also will be taking measures behind the scenes, using every city resource to ensure public safety.
The race is in its 44th year. It is held by the Atlanta Track Club, one of the largest running organizations in the U.S., which was founded in 1964.


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As a part of their any data, any size, anywhere initiative, at this year's PASS 2011 conference in Seattle Ted Kummert, Microsoft Corporate Vice President Business Platform Division announced Microsoft's intension to deliver Hadoop based data management to Windows Server and Windows Azure. Hadoop is a distributed computing platform that is written in Java. It uses a MapReduce technology to distribute computing resources across clusters of computers to rapidly process extremely high volumes of data.
Related: Microsoft SQL Serer 2012 Takes on Big Data with Hadoop
At first Microsoft's embracing of Hadoop may seem a bit confusing but when you view like their incorporation of OLAP services back in SQL Server 7 you can see that support for Hadoop is really another step along the evolutionary path of SQL Server becoming a complete enterprise data platform. Hadoop will enable the processing of high volumes of data as well as unstructured data. A CTP is planned to be released before the end of the year.
The Hadoop implementation will be integrated with both SQL Server relational databases as well as Analysis services. Microsoft announced Hadoop Connectors for SQL Server and the Parallel Data Warehouse. Customers can use these connectors for bi-directional integration of Hadoop with SQL Server's relational and BI data. Hadoop data will be able to be consumed using Microsoft's BI tools, including Microsoft PowerPivot and Power View.