An experimental study has been carried out of the osmotic pressure of solutions of the isotope He/sup 3/ in liquid He/sup 4/ at low temperatures, between 0.8 and 1.2 deg K. A superleak, a tube packed with a fine powder, acted as a semipermeable membrane which allowed only the superfluid He/sup 4/ to pass. The conclusion from these experiments was that the measured osmotic pressures were in reasonable agreement with values expected from the thermodynamic relations with other equilibrium properties of the mixtures, notably their vapor pressures. Thermodynamic equilibrium therefore seemed to have been attained under the conditions of the experiments. The second half of this paper concerns a study of the cooling which must take place during the adiabatic dilution of He/ sup 3/ by He/sup 4/. If the dilution is carried out at low temperatures where the solutions separate into two phases, the absorption of heat is estimated to be usefully large. After dilution the solution can be distilled, condensed and recirculated so as to make a continuously acting refrigerator. It should be possible to operate at temperatures of 0.1 deg K or below. (auth)


Shipbuilders have become extremely competitive in the world market over the past 20 years. Each company is forced to develop massive cost reduction and labor force reduction measures. After having given attention to the cost reduction possibilities on the steel construction side, the shipyard has concentrated specially on the reduction of the time verse space relationship and the dependency of engine room outfitting on ship block assembly at the slipway. This consideration led to the modularization of large engine room sections into functional modules. The use situation of module is not good although the use of module in Japan shipyards has a long history. The cause is analyzed and some advices are given based on the investigation in this paper.


: In furrow irrigation, the maximum lateral movement of water in ridges is more desirable than the vertical downward movement. This can be achieved by compacting the furrows. Thus, the study examines the impact on furrow soil compaction by tractor wheel trafficking during mechanical operations in the different soil types. In this experiment, the three-wheel tractor compaction includes: 1) control (no soil compaction), 2) compaction through 3-wheel tractor passes, and 3) compaction through 6-wheel passes under three different soil textural classes such as: clay loam, silty clay loam and silty loam soils. The impact of various treatments on clay loam, silty clay loam, and silty loam under 3- and 6-wheel passes showed increased bulk density (7–12%), field capacity (9–19%), ridge storage efficiency (35–38%), water use efficiency (16–20.5%) and decreased soil porosity (7–16%), infiltration (8–20%), and furrow storage efficiency (28–41%) over the control. This study shows comparable results of 6-passes with other studies in which more than 6-passes were used to compact the soil. This study suggested that farmers can maximise water use efficiency by compacting their furrows using 6-passes tractor trafficking.


The fatty change in the liver induced in male rats by a new antide‐pressant, maprotiline, given at high‐dose was studied morphologically and biochemically.


In this article, X ray plain films with 111 cases calcification of breast were analyzed conjioning with clinical characteristics and pathologic data, and it was found that the features of calcification were contribute to differention of the benign or the malignant. Of the 111 cases, 78 cases were showed benign lesions, and 33 cases malignant lesions. It was concluded that calcification was not the sepecific sign for the carcinoma of breast, which also was seen in benign lesions of breast. If mutiforms and irregular calcifications were appeared in cluster of particle calcification, malignant diagnosis would be predicted.


In order to improve military sci-tech journal editors' competence in their work,we analyze the problems which is likely to appear during examining political standpoint and security of manuscripts combining the characteristics of military sci-tech journals,and propose some measures.Then,we discuss how to cultivate potential contributors,amplify sources of manuscripts and improve impacts of military sci-tech journals.


A 60-year-old man who had a partial gastrectomy for gastric cancer 10 years ago was referred to our hospital for further examination for liver tumor. He was diagnosed as leiomyosarcoma of residual stomach associated with liver metastases. After preoperative transarterial embolization (TAE) with epirubicin of the anterior branch of right hepatic artery, residual stomach was resected, and the reservoir catheter and infusion arterial port were implanted. He was treated by intra-hepato-arterial chemotherapy of epirubicin. The patient has remained well for 2 years and 3 months without apparent complications.


PURPOSE
To develop and demonstrate the efficacy of a novel head-and-neck multimodality image registration technique using deep-learning based cross-modality synthesis.

METHODS AND MATERIALS
25 head-and-neck patients received MR and CT (CTaligned ) scans on the same day with the same immobilization. 5-fold cross validation was used with all of the MR-CT pairs to train a neural network to generate synthetic CTs from MR images. 24 of the 25 patients also had a separate CT without immobilization (CTnon-aligned ) and were used for testing. CTnon-aligned 's were deformed to the synthetic CT, and compared to CTnon-aligned registered to MR. The same registrations were performed from MR to CTnon-aligned and from synthetic CT to CTnon-aligned . All registrations used B-splines for modeling the deformation, and mutual information for the objective. Results were evaluated using the 95% Hausdorff distance among spinal cord contours, landmark error, inverse consistency, and Jacobian determinant of the estimated deformation fields.

RESULTS
When large initial rigid misalignment is present, registering CT to MRI-derived synthetic CT aligns the cord better than a direct registration. The average landmark error decreased from 9.8±3.1mm in MR→CTnon-aligned to 6.0±2.1mm in CTsynth →CTnon-aligned deformable registrations. In the CT to MR direction, the landmark error decreased from 10.0±4.3mm in CTnon-aligned →MR deformable registrations to 6.6±2.0 mm in CTnon-aligned → CTsynth deformable registrations. The Jacobian determinant had an average value of 0.98. The proposed method also demonstrated improved inverse consistency over the direct method.

CONCLUSIONS
We showed that using a deep learning derived synthetic CT in lieu of an MR for MR→CT and CT→MR deformable registration offers superior results to direct multimodal registration.


Objective To study the relationship between irritable hyperglycemia,serum insulin and quality,position,size of the focuses. Methods Examined the fasting blood glucose (FBG) and the fasting serum insulin(FINS) of patients who had fallen acute cerebral vascular disease(ACVD) in one week though double blindness way. Divided them into two groups,100 cases every group,in which one were those in high FBG,the other were in normal FBG. Recorded niduds quality,nidus position,nidus size of patients with high FBG according to CT and MRI. Results There was positive correlation between FBG and FINS in high blood glucose group. The level of hyperglycemia had markable difference in niduds quality,nidus position and nidus size through stactical management. Conclusion Irritable hyperglycemia of ACVD had correlation with insulin resistance. The increasing level of blood glucose was apparent in intracerebral hemorrhage,large size nidus and which focus near midline of brain compared with ischemia,small size nidus and which focus far away from midline of brain.


problems with access to elective surgeries in the country. Data collected over the past 30 years reveals a steady deterioration in access to such care across Canada. International data suggests that for many years Canadians have endured some of the longest delays in the developed world while they wait for access to medically necessary care. The COVID-19 pandemic has simply put an additional strain on our already fragile health-care systems.


Control intelligence is a typical field where there is a trade-off between target objectives, and researchers in this field have longed for artificial intelligence that achieves the target objectives. Multi-objective deep reinforcement learning was sufficient to satisfy this need. In particular, multi-objective deep reinforcement learning methods based on policy optimization are leading the optimization of control intelligence. However, multi-objective reinforcement learning has difficulties when finding various Pareto optimals of multi-objectives due to the greedy nature of reinforcement learning. We propose a method of policy assimilation to solve this problem. This method was applied to MO-V-MPO, one of preference-based multi-objective reinforcement learning, to increase diversity. The performance of this method has been verified through experiments in a continuous control environment.


Mechanized harvesting is one of the components of agricultural mechanization used to overcome grain losses and enhance the production compared to the conventional harvesting. Power tiller operated reapers are quite effective for harvesting practices in small fields and especially in mountainous regions where the crops are grown on terraces. Compared to the tractor mount reaper and combine harvester, it saves fuel and cuts the maximum straw to produce the fodder of almost 4000 kg ha-1 after the threshing operation. Thus, in case of wheat crop, it helps to save a significant energy of 1,524,000 kcal ha-1 avoiding the environmental pollution by infield burn of the straw. However, un-optimized use of power tiller operated reaper may result in high maintenance cost, low efficiency and distress among the small land holding farmers. The main objective of this study was to quantify the optimum cutting knife dynamics by optimizing the performance parameters of power tiller operated reaper like cutting speed, operating speed, cutting index, field capacity and fuel consumption. A combination of forward speed at 2.82 km h -1 and cutting speed at 3.42 km h-1 with cutting index of 1.21 was found to be most effective for a minimum grain harvesting loss of 101.33±1.0 kg ha-1 at a fuel consumption of 6.27±0.030 L ha-1 . A higher field efficiency of 71% was also recorded at cutting index of 1.21 for the same combination of forward and cutting speeds. Locus of cutter bar knife for the optimum combination of forward and cutting speeds helped to examine the operation of crank and cutter bar, prolonging the life of cutting mechanism. Thus, optimized performance of power tiller operated reaper will help to attain higher field efficiency at low fuel consumption and low maintenance.


Observations of living flower–heads of Tussilago farfara with ultraviolet light have confirmed the previously known distinction between the UV absorbing disc–flowers and the UV reflecting ray–flowers. A further differentiation of the yellow colours in the capitulum is that the anther walls fluoresce when exposed to UV light.


Unextendible product basis (UPB), a set of incomplete orthonormal product states whose complementary space has no product state, is very useful for constructing bound entangled states. Naturally, instead of considering the set of product states, Bravyi and Smolin considered the set of maximally entangled states. They introduced the concept of unextendible maximally entangled basis (UMEB), a set of incomplete orthonormal maximally entangled states whose complementary space contains no maximally entangled state [Phys. Rev. A 84, 042,306 (2011)]. An entangled state whose nonzero Schmidt coefficients are all equal to 1 / k is called a special entangled state of "type k". In this paper, we introduce a concept named special unextendible entangled basis of "type k" which generalizes both UPB and UMEB. A special unextendible entangled basis of "type k" (SUEB k ) is a set of incomplete orthonormal special entangled states of "type k" whose complementary space has no special entangled state of "type k". We present an efficient method to construct sets of SUEB k . The main strategy here is to decompose the whole space into two subspaces such that the rank of each element in one subspace can be easily upper bounded by k while the other one can be generated by two kinds of the special entangled states of "type k". This method is very effective when k = p m ≥ 3 where p is a prime number. For these cases, we can obtain sets of SUEB k with continuous integer cardinality when the local dimensions are large.


The enzymatic activity and function of a new α‐1,3‐glucosyltransferase, Cps18CU, derived from Streptococcus pneumoniae serotype 18C was identified for the first time using the enzymatically synthetic disaccharide Rhaβ1,4‐Glcα‐PP‐O(CH2)11‐OPh as the acceptor substrate. Further investigation on substrate specificity revealed that Cps18CU exhibited broad toleration toward various NDP‐Glc donors and also accepted such disaccharide acceptor containing Rhaβ1,4‐Glc moiety in structure. Finally, Cps18CU was employed into a one‐pot two‐enzyme reaction system, furnishing trisaccharide Glcα1,3‐Rhaβ1,4‐Glcα‐PP‐O(CH2)11‐OPh in an 81 % yield.


We report the analysis of femtosecond laser modification of poly(methyl methacrylate) (PMMA) by detection of optical signals emitted from the sample coaxially with laser beam. The influence of pulse duration, energy and burst pattern on recorded spectra was investigated using TruMicro 2000 laser. We present images of internal structures in polymer as well as the spectra of conical emission created as result of laser – polymer interaction. Generation of a broadband continuum signal was detected and analysed in a function of position of the focal plane. Furthermore, third harmonic generation and second harmonic of fundamental 1030 nm wavelength was detected and the origin of these signals is discussed. We present possibility of the material modification process monitoring by in situ spectral analysis of light coming out from the sample. The deposited pulse energy fraction was analysed.


Objective To investigate the clinical value of UmAlb and SCys-C levels in the patients with early renal function injury caused by hypertension.Methods The concentration of U-mALb,SCYs-C in 63 cases of patients with Ⅰ,Ⅱ and Ⅲ of primary hypertension and 52 cases of healthy controls were determined with immune transmission nephelometry.Results U-mAlb and SCys-C levels in hypertension with proteinuria and not were higher than of that of normal control(P0.01).U-mAlb and SCys-C levels in hypertension of Ⅰ,Ⅱ and Ⅲ were higher than of that of normal control(P0.01).Conclusion U-mAlb and SCys-C are sensitive indexes of early renal function injury.The combined determination of U-mAlb and SCys-C is useful for early diagnosis and intervention for hypertension.


Computers are increasingly being incorporated in devices with a limited amount of available memory. As a result research is increasingly focusing on the automated reduction of program size. Existing literature focuses on either data or code compaction or on highly language dependent techniques. This paper shows how combined code and data compaction can be achieved using a link-time code compaction system that reasons about the use of both code and data addresses. The analyses proposed rely only on fundamental properties of linked code and are therefore generally applicable. The combined code and data compaction is implemented in SQUEEZE, a link-time program compaction system, and evaluated on SPEC2000, MediaBench and C++ programs, resulting in total binary program size reductions of 23.6%-46.6%. This compaction involves no speed trade-off, as the compacted programs are on average about 8% faster.


The operating theatre is a very complex environment shared, for a certain period, by a group of people having highly different needs: on one side, there is the surgical team that must carry out a demanding job that in some cases can be very stressful (e.g. orthopedics surgery or those lasting more than four hours) and on the other, there is the anesthetized patient often subject to liquid infusion. Up to today little consideration has been given to the different needs of the surgical team whose members show different reactions according to their positions with respect to the scialytic lamp and above all to the task had within the team. Also the clothing influences the surgical team comfort degree: in fact, in some surgery (orthopedics, neurosurgery etc.) surgeons and assistants must wear non transpiring paper overalls beneath plasticized overalls besides protective masks and caps; then, if X-rays are needed during surgery, the second surgeon and the assistants must also wear lead overalls and lead thyroid collars and gloves while the anesthetists and nurses will keep on wearing non transpiring paper overalls; therefore the clothing thermal resistance of the surgical staff involved in the same surgical operation should be very different. The purpose of the present work is to report the first data obtained during an experimental campaign carried out at the SS. Annunziata hospital in Cento (Ferrara, Italy) and presents the developed investigation methodology.


Much instrumentation, especially older units, requires a substantial flow of tap water coolant for system heat removal. In many cases, it is becoming more economical to avoid the water consumption costs by switching over to a closed-system recirculating cooler. This can result in conservation of water as a resource and also provide more reliable instrument operation. Independence from local water supply pressure and temperature fluctuations is a real benefit. Anyone who has had to shut down a mass spectrometer's oil diffusion pumps on an emergency basis because of backed up plumbing and overflowing drains can attest to this. Eliminating the need for regular maintenance of tap water filters is another advantage.


pharmacokinetics and pharmacodynamics of piroxicam. Clin Pharmacol Ther 2006; 80:549–551. 3 Wang R, Chen K, Wen SY, Li J, Wang SQ. Pharmacokinetics of glimepiride and cytochrome P450 2C9 genetic polymorphisms. Clin Pharmacol Ther 2005; 78:90–92. 4 Lundblad MS, Ohlsson S, Johansson P, Lafolie P, Eliasson E. Accumulation of celecoxib with a 7-fold higher drug exposure in individuals homozygous for CYP2C9*3. Clin Pharmacol Ther 2006; 79:287–288.


Fault-tolerant logic circuits have been considered untestable due to the redundancy introduced into the logic circuits to mask faults. Recently, the block design concepts have been used to construct system and gate level fault-tolerant logic circuits and to find a minimal design. Conditions have been established to construct testable fault-tolerant circuits. This paper investigates the use of the block design concepts to generate test patterns for fault-tolerant logic circuits designed according to certain criteria. Algorithms are developed to construct fault-tolerant circuits and to generate minimal test patterns directly from the block design representation of the circuits.


Pedestrian safety has become a critical consideration in developing society especially road traffic, an intelligent transportation need of the hour is the solution left. India tops the world with 11% of global road accidents. With this data, we have moved in the direction of computer vision applications for efficient and accurate pedestrian detection for intelligent transportation systems (ITS). The important application of this research is robot development, traffic management and control, unmanned vehicle driving (UVD), intelligent monitoring and surveillance system, and automatic pedestrian detection system. Much research has focused on pedestrian detection, but sustainable solution-driven research must still be required to overcome road accidents. We have proposed a wireless sensor network-based pedestrian detection system that classifies the real-time set of pedestrian activity and samples the reciprocally received signal strength (RSS) from the sensor node. We applied a histogram of oriented gradient (HOG) descriptor algorithm K-nearest neighbor, decision tree and linear support vector machine to measure the performance and prediction of the target. Also, these algorithms have performed a comparative analysis under different aspects. The linear support vector machine algorithm was trained with 481 samples. The performance achieves the accuracy of 98.90%and has accomplished superior results with a maximum precision of 0.99, recall of 0.98, and F-score of 0.95 with 2% error rate. The model's prediction indicates that it can be used in the intelligent transportation system. Finally, the limitation and the challenges discussed to provide an outlook for future research direction to perform effective pedestrian detection.


The contribution of this paper is twofold: we introduce a new kind of assessment developed to capture students' learning in makerspaces, and we present a new perspective on how participating in a maker workshop impacts students. As opposed to traditional pen and paper tests, we designed a series of hands-on task that participants complete before and after a maker workshop. In this paper, we contrast high-school students' performance with experts (graduate students in mechanical engineering) and found evidence that the students' behavior became more similar to experts' after participating in a maker workshop. For the scope of this paper, we focus on a single task and describe in detail our coding scheme and analyses. Additionally, we show how a combination of qualitative and computational analysis helped us develop metrics to compare novices' and experts' performances. We conclude by discussing the potential of this type of assessment for supporting students' learning in makerspaces.


Comprising a compound having an epoxy resin curing agent composition and at least one vicinal epoxy group; (i) at least one adjacent compound having an epoxy group and (ii) an amino epoxy resin curing agent composition comprising the reaction product of an alcohol the epoxy resin composition; and the epoxy resin curing agent particles and at least one powder coating composition comprising particles of a compound having a vicinal epoxy group of the composition.


This work finds abnormal sub-threshold swing (S.S.) degradation under dynamic hot carrier stress (HCS) in n-channel metal-oxide-semiconductor field-effect-transistors with high-k gate dielectric. Results indicate that there is no change in S.S. after dynamic HCS due to band-to-band hot hole injection at the drain side which acts to diminish the stress field. Moreover, the impaired stress field causes the interface states to mainly distribute in shallow states. This results in ON state current and transconductance decreases, whereas S.S. degradation is insignificant after dynamic HCS. The proposed model is confirmed by one-side charge pumping measurement and gate-to-drain capacitance at varying frequencies.


Mobile  Ad-Hoc  Networks  (MANETs)  are  becoming  increasingly  popular  as  more  and  more mobile devices find their way to the public. A crucial problem in Ad-Hoc networks is finding an efficient route  between  a source  and a  destination.  Due to MANET' s  inherent characteristics,  secure  routing  it is  one  of  the  most  difficult  areas  to  tackle  because  opponents  will  add themselves  to  a  MANET  using  the  existing  common  routing  protocols.  Hence,  this  paper proposed a new model of routing protocol called ARANz, which is an extension of the original Authenticated  Routing  for  Ad-Hoc  Networks  (ARAN).  Next to this  the  authentication  methods adopted from ARAN, ARANz aims to increase security, achieve robustness and solve the single point of failure and attack problems by introducing multiple Local Certificate Authority servers. increasingly,  by dealing  with  the  network as zones  and using restricted directional  flooding, our new  model  will  exhibit  better  scalability  and  performance.  An  overview  and  a  qualitative comparison between ARANz  and  some  existing  Ad-Hoc routing  protocols  is  presented  in this paper.


String theory, as a theory containing quantum gravity, is usually thought to require more dimensions of spacetime than the usual 3+1. Here I argue on physical grounds that needing extra dimensions for strings may well be an artefact of forcing a fixed flat background space. I also show that discrete simplicial approaches to gravity in 3+1 dimensions have natural string-like degrees of freedom which are inextricably tied to the dynamical space in which they evolve. In other words, if simplicial approaches to 3+1 dimensional quantum gravity do indeed give consistent theories, they may essentially contain consistent background-independent string theories.


Isotope-labeled drug molecules may be useful for probing by NMR spectroscopy the conformation of ligand associated with biological hosts such as membranes and proteins. Triple-labeled [7,9,19-13C3]-vitamin D3 (56), its 25-hydroxylated and 1α,25-dihydroxylated metabolites (58 and 68, respectively), and other labeled materials have been synthesized via coupling of [9-13C]-Grundmann's ketone 39 or its protected 25-hydroxy derivative 43 with labeled A ring enyne fragments 25 or 26. The labeled CD-ring fragment 39 was prepared by a sequence involving Grignard addition of [13C]-methylmagnesium iodide to Grundmann's enone 28, oxidative cleavage, functional group modifications leading to seco-iodide 38, and finally a kinetic enolate SN2 cycloalkylation. The C-7,19 double labeling of the A-ring enyne was achieved by the Corey−Fuchs/Wittig processes on keto aldehyde 11. By employing these labeled fragments in the Wilson−Mazur route, the C-7,9,19 triple-13C-labeled metabolites 56, 58, and 68 as well as other 13C-lab...


Abstract The objective of this study was to characterize cellulose nanocrystals /TPS-based nanocomposites. Nanocrystalline cellulose was isolated from cotton linters using sonochemical method and characterized through WXRD, TEM, and FTIR. These nanocrystals were then dispersed in glycerol and sorbitol plasticized starch using a Fluko high shear homogenizer in varying proportions and films were cast. The films were characterized using WXRD, SEM, and mechanical properties. TEM images of nanocrystals revealed a diameter of 20–30 nm and length 200–300 nm. XRD results for nanocomposite films for both the plasticizers showed 2θ peaks at 14.8°, 16.7,° and 22.5°. Elastic modulus increased with addition of cellulose nanocrystals and tan δ shifted toward higher temperature for both the plasticizers. Mechanical properties improved more than 200% for both glycerol and sorbitol plasticized nanocomposites.


A method for the purification of crude acetonitrile comprising distilling the crude acetonitrile in a first fractional distillation column at below atmospheric pressure, withdrawing a first side draw fraction comprising acetonitrile, distilling the first side draw fraction in a second fractional distillation column at super atmospheric pressure, and withdrawing from the second distillation a second side draw fraction comprising purified acetonitrile.


Background It is still unclear whether long-distance running has a deleterious effect on joint health; therefore, this study was undertaken to examine the rate of recovery from alterations occurring at the knee joint in marathon runners due to loading. Hypothesis Tibial, patellar, and meniscal cartilaginous volumes are able to recover adequately from changes due to repeated loading immediately after cessation. Study Design Controlled laboratory study. Methods Twenty knees of male athletes were studied (mean age, 38 ± 14 years). The participants ran 20 km around a predetermined and precisely measured course. Cartilaginous volume was measured by magnetic resonance imaging before the run (60-min rest before exercise), immediately after the run (3-min delay), and after a recovery period of 1 hour. Results After the 20-km run, there was a significant transient decrease in cartilage volume. After 1 hour of rest, no significant reduction of cartilage volume was measured for the patella (−2.1 %), the tibia (−1.2%), the lateral meniscus (−3.2%), or the medial meniscus (−5.9%). However, the values recorded for the menisci were borderline, which indicates that recovery of meniscus volume lags behind that of articular cartilage. Conclusion Our data indicate a clear tendency toward rapid recovery of the cartilaginous and meniscal volumes at the knee. The results of this study lead to the assumption that the cartilage and the menisci are well able to adapt to the loads caused by running. Investigation of more subtle changes would require more specific magnetic resonance imaging techniques, including T2-weighted mapping and T1-weighted rho sequences, to assess cartilage biochemistry. Clinical Relevance The articular structures were investigated on a general magnetic resonance imaging level and were found to recover rapidly so that exercise could be continued after a short time without reservation.


The Japanese word kawaii means 'cute', 'lovable' or 'adorable' and is used to express the quality of cuteness or kawaii aesthetics in the general context of Japanese culture. This concept has become prominent in many aspects of Japanese modern culture, including clothing, personal appearance, food, toys, behaviour and mannerisms. While entities culturally characterized as kawaii are considered adorable and delicate, they also tend to appeal to people's deep inward affections in a visceral manner. Scholarly discussions of kawaii have tended to focus on specific entities like commodified objects or school children, and these target entities are treated as relatively isolable units that happen to be imbued with kawaii attributes. Concomitantly, this also means that the question of how kawaii entities or other features associated with kawaii aesthetics might be integrated into the broader sociocultural environment has tended to remain relatively underexplored. Drawing attention to kawaii as a key component of Japanese material culture, this paper investigates selected kawaii data taken from banal civic signs in Tokyo's semiotic landscapes. We then analyse the role of kawaii in matters traditionally not associated with kawaii through the lens of affection and viscerality.


The purpose of this study was to determine the effect of organizational justice on job satisfaction and organizational commitment in the Department of Housing and Settlements in Denpasar City. This research was conducted on employees of the Housing and Settlement Area and Denpasar City. Samples taken were 100 respondents. Sampling in this study used proportionate random sampling technique. Data collection was carried out by distributing questionnaires using a 5-point Likert scale to measure 28 statement items. The analytical technique used was an Islamic Path. The results of the analysis show that organizattional justice has a positive also significant effect on both job satisfaction and organizational committment. Job satisfaction has a positive and significant effect on organizational commitment. This study also succeeded in proving that job satisfaction mediates the influence of organizational justice on organizational committment in the Department of Housing, Settlements and Land Affairs of Denpasar City.

Keyword : organizational justice, job satisfaction, organizational commitment


Abstract. Mediterranean grasslands are highly seasonal and co-limited by water and nutrients. In such systems little is known about root dynamics which may depend on plant habit and environment as well seasonal water shortages and site fertility. This latter factor is affected by the presence of scattered trees and site management including grazing, as well as chronic nitrogen deposition, which may lead to N:P imbalance. In this study we combined observations from minirhizotrons collected in a Mediterranean tree-grass ecosystem (Spanish Dehesa), with root measurements from direct soil cores and ingrowth cores, and above-ground biomass to investigate seasonal root dynamics and root:shoot ratios. We investigated responses to soil fertility, using a nutrient manipulation (N / NP additions) and microhabitats effects between open pasture and under tree canopy locations. Root dynamics over time were compared with indices of above-ground growth drawn from proximal remote sensing (Normalised Difference Vegetation Index and Green Chromatic Coordinate derived from near-infrared enabled digital repeat photography). Results show distinct differences in root dynamics and biomass between treatments and microhabitats. Root biomass was higher with N additions, but not with NP additions in early spring, but by the end of the growing season root biomass had increased with NP in open pastures but not higher than N alone. In contrast, root length density (RLD) in pastures responded stronger to the NP than N only treatment, while beneath trees RLD tended to be higher with only N. Even though root biomass increased, root:shoot ratio decreased under nutrient treatments.We interpret these differences as a shift in community structure and/or root traits under changing stoichiometry and altered nutrient limitations. The timing of maximum root cover, as assessed by the minirhizotrons, did not match with above-ground phenology indicators at the site as root growth was low during autumn despite the greening up of the ecosystem. In other periods, roots responded quickly to rain events on the scale of days, matching changes in above-ground indices. Our results highlight the need for high resolution sampling to increase understanding of root dynamics in such systems, linkage with shifts in community structure and traits, and targeting of appropriate periods of the year for in-depth campaigns.


We report 2 patients with idiopathic refractory sideroblastic anemia who developed chronic myelomonocytic leukemia 1 to 5 yr later. This observation supports the decision of the FAB cooperative group to include both conditions in the category of myelodysplastic syndrome.


This paper deals with the estimation of transfer entropy based on the k-nearest neighbors (k-NN) method. To this end, we first investigate the estimation of Shannon entropy involving a rectangular neighboring region, as suggested in already existing literature, and develop two kinds of entropy estimators. Then, applying the widely-used error cancellation approach to these entropy estimators, we propose two novel transfer entropy estimators, implying no extra computational cost compared to existing similar k-NN algorithms. Experimental simulations allow the comparison of the new estimators with the transfer entropy estimator available in free toolboxes, corresponding to two different extensions to the transfer entropy estimation of the Kraskov–Stogbauer–Grassberger (KSG) mutual information estimator and prove the effectiveness of these new estimators.


Objective To evaluate the safety and efficacy of the AtricureTM bipolar radiofrequency ablation(BRFA) modified maze procedure for atrial fibrillation(AF) with large left atrium under the open-heart surgery.Methods 30 cases with rheumatic heart disease and AF underwent BRFA combined with open-heart surgery.The clinical data was retrospectively analyzed.Results All operation was successful.Cardiopulmonary bypass,aortic clamp and BRFA were(108.2±25.3),(69.6±23.1) and(18.7±2.6) minutes,respectively.All patients were sinus rhythm after the hearts beat again.No high degree atrioventricular block and operation death were found.Hospital stay was mean(11.8±3.7) days.The rate of freedom from AF was 83.3%(25/30) and the rate of restoration to sinus rhythm was 76.7%(23/30).Conclusion BRFA is also a safe and valid treatment in eliminating AF of large left atrium patients.


Sedimentary basin is consided as a goodynandc system band on the lithospher plate fornic theory. Authors creatal an integfatal geophysical interpretahon and dynawhc modeling Syta of ndirnentary basins. In order to probe int0 basin evoluhon history, weconductal comprehensive studies of a basin by using gravity, magnetism, seisrnology and well log data, and bolatal subSidence, thennal, hydrocarb0n generah0n and ndgrah0n his tory of a basin. Usng the sydri, we Stlldied the East China Sca geophysical features,and itS subsidence and thennal histories.


It is reasonable for the backward countries taking trade protection measures during the primary stage of industrialization.But as the economic development goes further,the social and economic conditions of trade protection policies are disappearing gradually.In the era of knowledge -based economy and economic globalization,free trade policies will be the short cut for the developing countries.China's WTO entry just embodies the request of the economic development.


Greenhouse and laboratory studies were conducted to investigate the allelopathic potential of alfalfa and vetch residues on soybean and corn using various extract concentrations (0, 5, 10, 15 and 20%, w/v) and residue rates (0, 0.25, 0.5, 0.75 and 1%, w/w). Aqueous extracts of alfalfa (Medicago sativa L.) and vetch (Vicia spp.) exhibited an allelopathic effect on soybean and corn seed germination, seedling length and weight. The degree of inhibition significantly increased as the aqueous extract concentration increased. Alfalfa and vetch 20% extracts reduced soybean seed germination, seedling length and weight by 35%, 57%, 32% and 15%, 42%, 25% respectively, when compared to control. Corn germination, seedling length and weight was inhibited by 20%, 23%, 38% by alfalfa and 19%, 18%, 35% by 20% vetch extracts. Alfalfa and vetch extracts inhibited secondary root formation and branching as the extract concentration increased. Alfalfa and vetch 20% extracts inhibited by 41% and 32% secondary root numbers, respectively as compared to control. It was found that the aqueous extract of alfalfa resulted in greater reduction in germination, seedling length and weight of soybean than that of vetch. Alfalfa and vetch 1% residue rate inhibited soybean plant height by 30% and 10%, leaf area by 31% and 23%, and dry weight by 18% and 1%, nodule number by 27% and 20% also. Alfalfa and vetch residue significantly enhanced plant height, leaf area and dry weight of corn. The maximum stimulation occurred with 0.25% and 1% of alfalfa and vetch residue rates, respectively. Plant height, leaf area, and dry weight increased by 23%, 59%, 58% and 17%, 52%, 94% with alfalfa and vetch residues of 0.25% and 1%, respectively. This study demonstrates that there is an allelopathic potential resulting from alfalfa and vetch residues on soybean growth and yield. It also suggests that these residues may affect crop growth and development due to the inhibitory or stimulatory effects of allelochemicals existing in the residue.


The ever-growing complexity of construction projects on the one hand, and the increasing use of emerging technologies in the AEC industry on the other hand, have significantly escalated computational complexity. This trend is expected to continue. However, conventional computing tools and technologies highly rely on classical computing techniques that may not be able to handle computational tasks which become larger and more complex over time. Quantum computing (QC) is a fast-evolving technology that promises to completely revolutionize the computation capabilities in various fields, including engineering, by enabling complex computations that currently are impossible or prohibitively time consuming. As a result, QC can be seen as a next-generation solution to address computational challenges arising in the AEC's today and future. However, scant attention has been drawn to what the QC can bring to the AEC industry. This study reviews the existing QC literature to explore AEC applications that could benefit from QC-based methods, and the potential challenges associated with their implementation in the AEC industry. Illustrating a clear outlook of the potential advantages and challenges, the study also helps to set realistic expectations over the potential improvement that QC can offer over conventional techniques.


A case is reported of a patient with periodic persistent hiccups and secondary generalised epilepsy lasting for a period of five years following a right temporal brain abscess. The recurring episodes of hiccups had a ten day rhythmicity and unlike epileptic convulsions were unresponsive to treatment.


This paper shows an approach to the evaluation of mission scenarios that involves motion and mobile network communications for groups of vehicles, using the Hybrid Operational Protocol Evaluation (HOPE) tool. HOPE is a framework that combines simulation models of communication protocols, terrain maps, link budget reporting services, scenario network visualizations, statistics gathering and displays, and other mission resource expenses (fuel, ammunition, battery power, etc.). Users can create scenarios and execute scenario simulation models with external simulation environments, such as OPNET, QualNet, MATLAB, etc. HOPE refines simulation results with terrain obstructions and atmospherics. HOPE also animates scenarios, visualizing vehicle motion and communication over 3D geographical maps, and provides the scenario statistical reports. HOPE estimates resources necessary to accomplish the mission in different terrain and climatic circumstances. 3D animation of mission execution, together with statistical charts, helps detect logistical flaws in the mission plan. Varying scenario parameters allows users to find an optimal plan for the mission. HOPE executes and visualizes more than one simulation model using one scenario.


BACKGROUND
There is strong evidence supporting fasting guidelines of 6 hour fast from solids and 2 hour fast from fluids prior to surgery. Despite this, patients spend prolonged periods of time fasting for surgery with a lack of research to support translating this evidence into practice, particularly for emergency surgical theatres lists. This study aims to explore barriers and enablers to reduce prolonged fasting for patients on emergency surgical lists in the acute care setting.

METHODS
Qualitative interviews were undertaken with twenty-two health professionals on acute surgical wards within a quaternary referral hospital in Sydney, Australia. Semi-structured interviews explored barriers and enablers to implementing evidence-based fasting practices for patients on emergency surgical lists, using a theoretical domains framework. Interviews were transcribed verbatim and analyzed using an inductive thematic approach.

RESULTS
Key barriers to implementing reduced fasting included unpredictable, inflexible systems; cultural concerns; and gaps in knowledge. Major enablers to reducing fasting times is the recognition of patient distress caused by excessive fasting; and desire by all twenty-two interviewees to address the problem.

CONCLUSIONS
This research is the first to explore barriers and enablers to implementing interventions to address excessive fasting. This research highlights the complexity of the issue, and the need for a multi-faceted translational intervention addressing limitations in systems and cultural barriers. This article is protected by copyright. All rights reserved.


Because of the characteristics of matrix and fractures and low permeability in volcanic reservoirs,the Klinkenberg effect was induced in gas percolation and the unique medium and Darcy flow theory in conventional sandstone reservoirs were not suitable for these kinds of gas reservoirs.Aimed at the problem mentioned above,a percolation mathematical model was established in the consideration of Klinkenberg effect,double-medium,two phases of gas and water,the numerical solution was performed by using the finite difference method,and numerical simulation procedure was prepared.single well parameters of the SN volcanic gas field were used for numerical simulation.The results indicate that the production indexes considering the starting pressure gradient are higher than that no consideration,including the accumulative gas production,recovery percent and the ultimate recovery during the stable time.So during the production Klinkenberg effect should be considered.


Healthcare attorney Bruce Johnson and administrator Jim Gangelhoff discuss the various models of hospital-physician alignment and integration, the compliance issues each presents, and physician compensation methods and incentive structures that work.


In this paper I disscussed the the ontologies and An ontology can be defined as a shared conceptualisation of knowledge. Ontologies are used across a number of domains. Ontologies often contain a model of a domain, its taxonomy the relationships between its entities. Some ontologies are detailed enough to allow some level of reasoning. Ontologies are usually built by domain experts, who have a high degree of knowledge about their specific domain. A researcher suggests that one way to overcome knowledge sparseness is to enrich dictionaries (such as WordNet) and thesauruses. This research has taken the opposite path, taking a large training set and reducing it into a subject based classification system. The aim of this research was to quickly, cheaply and simply build an ontology which has both a wide range of knowledge and capabilities across many different domains. Examples of large ontologies are Cyc , ConceptNet , and ThoughtTreasure . These contain a large number of rules which are intended to allow some form of reasoning. The term "ontology" has a number of conceptions. For the purposes of this research, an ontology is defined to be a hierarchical structure, whereby the nodes correspond to subjects. This study makes use of world knowledge stored in an ontology and applies it to collection selection. Two strengths of using an ontology in Information Retrieval (IR) . Firstly, an Information Retrieval system using an ontology may improve its precision performance. The concepts embodied in the given query and documents can be identified and extracted along with their relationships from the ontology, which helps an IR system to restrict the search scope so that the retrieval precision can be improved. Secondly, an IR system using an ontology may improve its recall performance. The synonymous terms with the same concepts as the query terms can be extracted from the ontology. The IR system can use the synonymous terms to search instead of the original terms in the given query. As a result, the IR system does not have to rely on the exact terms occurred in both of the query and documents. Although some documents do not contain the query terms, as long as they discuss the same concepts as the given query, they may be identified and extracted. However, while the recall is improved by searching using the synonymous term, the precision may be hurt as the synonymous terms normally refer to a broader concept area than the original terms. This concept is similar to "query expansion",


The clinical differences between the types of cardiac pain have been described in a previous paper (Bourne, 1935) and have also been stressed in a later one, "Angina Innocens: A Clinical Study "* (Bourne, 1937). The present communication is a full analysis of a series of 112 patients suffering from the symptom of angina of effort. The method of presentation of these papers dealing with the various types of cardiac pain might suggest that an attempt was being made todescribe individual diseases. This is by no means the case, but the definite clinical pictures provided by the different varieties of cardiac pain are so clear and distinct that it is believed that the mechanisms vary in each individual type of pain. Since at the moment it is quite impossible to determine minor and transitory changes in the coronary circulation by any other means, a careful scrutiny of the symptomatologies is an essential method of approach to the problem. There are several possible organic causes of the symptom of angina of effort, presupposing this symptom to be the result of interference with coronary flow during exercise: coronary atheroma and syphilis of the aorta interfering with coronary flow are the commonest causes. Furthermore, cases have been described where severe anaemia was associated with angina of effort and where no evidence of cardiovascular disease was found at necropsy. (Cabot, 1926; Willius and Giffin, 1927; Elliott, 1934.) The large majority of the patients here described were presumably suffering from coronary atheroma; seven had syphilitic aortitis, and one of these also had hypertension; one patiert showed Addisonian anaemia as the only abnormality; and two had severe hypochromic anaemia; one of the last two, who in addition had aortic stenosis, lost his pain when the anaemia had responded to treatment.


We compare the canonical quantization and the effective action method to derive expectation values of the stress energy tensor for scalar fields conformally coupled to a 2D Schwarzschild black hole spacetime. Particular attention is devoted to the thermal equilibrium Hartle-Hawking state where the striking disagreement of the results may be reconduced to the incomplete knowledge of the effective action. We show how to reconcile the two procedures and find physically meaningful analytical approximate expressions for the stress tensor in the Hartle-Hawking state.


A novel broad band and wide beam microstrip helical antenna is proposed based on the modification of traditional helical antennas. Through selecting the appropriate operating mode between the axial mode and the normal mode, this new antenna can broad both the beamwidth and the bandwidth. To improve the gain of the antenna, An antenna array with 1*16 elements is designed and fabricated. Meanwhile, cavity-loaded feeding network is utilized for probe station measurement. The simulated impedance and radiation pattern are studied. The proposed antenna shows a wide impedance bandwidth from 7.6GHz to 9.6GHz for |S11|<-10dB, with wide 3dB beamwidth of E-plane about 1200, respectively.


The lolitrems, tremorgenic neurotoxins from perennial ryegrass, are implicated in ryegrass staggers disorder in livestock; the assignment of structure (1) to the major neurotoxin, lolitrem B, is based on its spectroscopic properties, particularly a detailed structure of its high-field 1H and 13C n.m.r. spectra, as well as chemical evidence.


A recurring claim in the literature is that active social media use (ASMU) leads to increases in well-being, whereas passive social media use (PSMU) leads to decreases in well-being. The aim of this review was to investigate the validity of this claim by comparing the operationalizations and results of studies into the association of ASMU and PSMU with well-being (e.g. happiness) and ill-being (e.g. depressive symptoms). We found 40 survey-based studies, which utilized a hodgepodge of 36 operationalizations of ASMU and PSMU and which yielded 172 associations of ASMU and/or PSMU with well-/ill-being. Most studies did not support the hypothesized associations of ASMU and PSMU with well-/ill-being. Time spent on ASMU and PSMU may be too coarse to lead to meaningful associations with well-/ill-being. Therefore, future studies should take characteristics of the content of social media (e.g. the valence), its senders (e.g. pre-existing mood), and receivers (e.g. differential susceptibility) into account.


The work concerns with the acoustic emission source localisation in thin plate-like structures. An accurate approach has been proposed through the dispersion removal technique. The acquired signals are inherently deformed by the dispersive character of wave interaction with structure, and depend on the structural properties, e.g. material constants, geometry, source frequency content etc. The deformation of the signals increases with the propagation distance making the results interpretation difficult. Thus, the damage localisation is cumbersome and prone to errors. Authors propose an application of dispersion removal technique to transform the AE signals from the time to the distance domain, showing explicitly the distance between the sensor and the source. A set of spectral characteristics is used to perform the mapping operation. Then, employing triangulation techniques the source is localised. The method is compared to the existing methods in terms of accuracy, showing the advantages of the proposed approach.


Based on optical triangulation measuring principle, an inner diameter non-contact measuring method is presented in this paper. First, the principle of optical single-triangulation which is used for non-contact measurement of inner diameter is analyzed and described. The corresponding formula for calculating the dimension of inner diameter is presented. The mathematics model for solving eccentricity of optical head which is adopted in the optical single-triangulation method is founded. The paper adopts optical single-triangulation measuring principle to design a system of inner diameter non-contact measurement with the technique of laser collimation, modern sensor, servocontrol, computer, etc. In this paper, the constitution and overall structure of the system are described, and also, the accuracy of system is verified by experiments. The measuring system resolving power can reach 0.01 mm, the limited measuring error not more than 0.03 mm. It indicates that the measuring method is applicable.


An extensive program of investment is at present planned--and partly also in execution--with the long-term aim of improving the economic situation of the German Federal Railway. The major tasks which will thereby result for the Ways and Works Department of the DB are dealt with here in their essentials, also the finance requirements and the agreed priorities.


Two cases of microcornea with typical coloboma of uvea and optic disc are presented. Both are young females. One case is bilaterally involved and the other is unilateral. Ultrasonography revealed normal axial length of globes which served for differential diagnosis from microphthalmos. In both cases, the chief complaint was poor vision caused by refraction error and colobomatous lesion involving the macula area. Funduscopy, fluorecein angiography and chromosome study were done and discussed.


We investigated the influence of UV $(\mathrm{KrF}, \ensuremath{\Elzxh}\ensuremath{\omega}=5.01 \mathrm{eV})$ pulsed laser irradiation on the atomic order and optical properties of amorphous YBaCuO films containing crystalline clusters of nanometer (up to 25 nm) size and characterized by high mobility of structural elements due to the lack of sharp interphase boundaries. The presence of crystalline clusters in amorphous medium leads to higher disorder of the latter, while electronic states in relatively narrow $(\ensuremath{\approx}2 \mathrm{eV})$ $\mathrm{Cu} {3d}^{10}$ band become localized and practically do not participate in optical transitions. We found that UV radiation destroys the crystalline clusters, increases order in the amorphous medium and initializes the processes of $(11l)+(10l)\ensuremath{\Rightarrow}(00l)$ orientational transition. Increase of atomic order results in partial delocalization of electron states in the $\mathrm{Cu} {3d}^{10}$ band and the conduction band switches over from $\mathrm{Cu} {4s}^{1}$ to $\mathrm{Cu} {3d}^{10}.$


In this study, four types of flood routing approaches were studied which give significantly varied results represented by the differences between computed and observed flows and also differ considerably on the friction coefficient and bed slope of the channels. First two approaches use a hydraulic solution to solve the equations of unsteady flow, while the third approach uses the hydrological solution, and the fourth algorithm solves Muskingum approach with seven parameters. All these approaches were run with the same input parameters, the results were compared and tested with four Error Measurement Indices, Sum of Squared Deviations, Error of Peak Discharge, Variance Index, and agreement index. Diyala River was selected for this application. Dynamic wave method gave accurate results, followed by the characteristic method, and then the linear Muskingum-Cunge method, but Symbiotic Organisms Search Algorithm not gave any senses due to change in roughness or bed slope and gave very identical values with recorded outflow in all conditions, which means that the hydraulic solution is better compared to the hydrological solution. The results also showed that the difference between the calculated and observed flows diminished with a decrease in the coefficient of friction and an increase in the bed slope channel.


purpose Silicone intubation has become popular in the treatment of nasolacrimal duct disorders during the last 25 years. Silicone tubes are well tolerated in the lacrimal drainage system, but the optimum duration of a successful intubation associated with the minimum number of complications has not yet been established. The aim of this study was to assess the complications of silicone intubation and their relation to the surface reaction on the tubes.method We followed 40 patients with silicone intubation after an endo-scopic endonasal dacryocystorhinostomy for 9 to 27 months. Both ophthal-mologic and intranasal endoscopic examinations were performed in the postoperative period;17 tubes removed from the patients were also examined for the cellular reaction on the tubes.results The lacrimal system was patent in 77.5% of the patients. There was no correlation between the length of intubation and the outcome. Complications included tube dislocation (2.5%), tube loss (7.5%), granuloma formation in punctum (5%...


examines, in Chapter Seven, the close interlinkage existing between lynching and the white supremacy ideology during the early 20th century. In the process, Professor Carrigan convincly demonstrates that the development of a lynching culture in Central Texas was dominated by four major factors : first, the frontier experience; second, racial slavery; third the resistance to lynching by racial, ethnic and political minorities; and the fourth and most important factor was the way the courts fluctuated between fighting or tolerating mob violence. Indeed, the frequent failure of the local authorities to prosecute mob leaders not only gave an implicit approval to lynching, but had also a lasting effect on that phenomenon. Writing in a crisp, clear style and demonstrating an impressive mastery of a wide range of primary and secondary sources, Carrigan raises several important questions about the evolution of the lynching culture in the South. The presence of a complete appendix on the victims of mob violence between 1860 and 1922 makes the book a useful tool of reference for those seeking information. It is to Carrigan's credit that he does not oversimplify all the underlying vigilantism revealed by his research. The quality of the research makes this study a detailed and judicious work that opens new paths for further work and enhances our global comprehension of this tragic phenomenon. The main quality of the present study restes on the author's ability to examine not only how the lynching phenomenon represented a cultural response in times of crisis but also how the role of the lynch mob fluctuated from one set of polarities to any other. In the process, the study shows the effects on a community of surrounding circumstances, such as frontier insecurity, slave control, racist mentality, war, reconstruction, and the general dependence of a community on forces beyond its control. While the entire book is of interest to the general reader, Carrigan's examnination of the formulation and influence of the lynching culture will be particularly interesting for professional historians.


SummaryIngestion of 300 cc. of water by fasting normal subjects causes a fall in the number of circulating eosinophils (about 25 %). Control experiments without water intake do not show any appreciable variation of the eosinophil count.


By its anatomical relationship with temporal lobe, auditory and visual pathways are susceptible to anatomical or functional changes after surgical resection of temporal lobe used as a therapeutic option in patients with mesial temporal lobe epilepsy drug-resistant (ELTm-FR). We studied a sample of 28 patients with ELTm-FR operated at the International Center of Neurological Restoration between 2002 and 2012, in order to evaluate possible changes of auditory and visual sensory systems secundary to the anterior temporal lobectomy guided by electrocorticography. It was noted the existence of functional abnormalities in auditory and visual sensory systems before surgical intervention in comparison with a group of healthy subjects. After resection were detected changes in the functioning of the auditory pathway through the use of auditory evoked potentials, probably mediated by an indirect effect and long-term removal of specific structures such as the amygdala and the middle temporal pole structures. In the visual pathway resection of epileptogenic zone prompted visual field defects that were evidenced by the techniques of visual evoked potentials with stimulation by quadrants in combination with perimetry, and which corresponded to the magnitude of the neocortical tissue removed. The visual pathway lesion could be substantiated through the tractography of optic radiation and the state of its connectivity. These results should be considered for the evaluation of patients with ELTm-FR who undergo surgical treatment.


FIELD: veterinary science. SUBSTANCE: invention relates to veterinary science and aims at prevention of infectious diseases in distal extremities of cattle. Iodprotectine dissolved in distilled water 1:5 is used as a preparation for prevention diseases. Thin layer is applied on the surface of all the extremities 1-2 times every 7-14 days. EFFECT: invention provides high preventive effect. 1 cl, 1 tbl, 1 ex


Ndfip1 is an adaptor for the E3 ubiquitin ligase Itch. Both Ndfip1- and Itch-deficient T cells are biased toward Th2 cytokine production. In this study, we demonstrate that lungs from Ndfip1 2 / 2 mice showed increased numbers of neutrophils and Th17 cells. This was not because Ndfip1 2 / 2 T cells are biased toward Th17 differentiation. In fact, fewer Ndfip1 2 / 2 T cells differentiated into Th17 cells in vitro due to high IL-4 production. Rather, Th17 differentiation was increased in Ndfip1 2 / 2 mice due to increased numbers of IL-6–producing eosinophils. IL-6 levels in mice that lacked both Ndfip1 and IL-4 were similar to wild-type controls, and these mice had fewer Th17 cells in their lungs. These results indicate that Th2 inflammation, such as that observed in Ndfip1 2 / 2 mice, can increase Th17 differentiation by recruiting IL-6–producing eosinophils into secondary lymphoid organs and tissues. This may explain why Th17 cells develop within an ongoing Th2 inflammatory response. The Journal of Immunology , 2012, 188: 4023–4031.


The constraint from causality on transition amplitude in relativistic quantum mechanics is proven for Dirac particle without and with interactions with external fields and for free scalar and vector particle in any (1+D)-dimensional Minkowskian space-time.


Jordan is one of the most ancient Arab civilizations, with a stable identity. To sustain this identity, Madaba-Jordan is a prominent name due to its famous handicraft works. However, due to the Covid-19 outbreak, the decreased tourism has also affected handicraft sales, leading to declined economic opportunities. This article attempted to investigate the potential strategies to resume handcraft sales to benefit both the local artists and the Jordanian Government. We executed a cross-sectional study design and selected a sample of n=422 mosaic customers. Findings obtained from the Structural Equation Modelling indicated a robust and significant relationship between the components of the Marketing Intelligence, and self-congruity (p ≥ 0.000), category involvement (p ≥ 0.000), and brand engagement (p ≥ 0.000). These results highlight that if the Jordanian mosaic industry focuses more on developing Marketing Intelligence, it will benefit both the handicraft workers and the local government. These benefits will be three-way, ensuring a sustained development opportunity for both involved parties. Thus, this project recommends more studies on the relevant topic, and for this purpose, a qualitative interview-based investigation directly from the workers will bring out even more significant outcomes.


In the 1980s, corporate strategists advised companies to focus on increasing related and decreasing unrelated diversification. We use industry participation counts and entropy diversification indexes based on Trinet data to examine whether restructuring by 10 of the largest food and tobacco manufacturing firms fits this scenario. Indexes measuring related diversification within and outside food and tobacco manufacturing, unrelated diversification, and total diversification lend mixed support to the scenario. While about half of the firms followed the suggested pattern, half did not. These results suggest the importance of focusing on the cumulative impact of changes in a firm's activities on its level of diversification. © 1995 John Wiley & Sons, Inc.


Modern garden has now turned its emphasis on the development of ecological gardens.This article deals with the contents and categories of flower plants in the city gardens.The applications and effects of various flowers in city gardens have been displayed in terms of their categories.The author points out those creating flower sceneries should take regions,positions,colors and seasons into consideration.


Heavy-oil is one of the main energy sources in the future. However, with the high viscosity of heavy oil, steam-flooding (SF) is one of the major techniques to produce this oil. To determine a favorable operating condition, many recent studies have evaluated the different methods like varying the well spacing and steam injection rates. However, there is no single optimum value for all reservoirs or all modes of operation. In this study, it's aimed to investigate the effects of well spacing, injection rate, and perforation on heavy oil production with low permeability in multi-layered heterogeneous reservoir. The practical field data was applied to simulate the SF process by using STARS, a CMG program. Production parameters such as injector – producer (inj. – prod.) distance from 141 m to 282 m and steam injection rates from 30 m3/d to 180 m3/d were evaluated to obtain the optimum conditions with 80 % steam quality. The entire project was considered for 20 years of production. From the results, it showed that the higher oil recovery can be achieved by increasing injection rate and/or shorten well spacing. In order to lower the steam consumption, the selective perforation in bottom layers was compared with full perforation strategy. With the balance between oil production and steam injection, about 60 % of steam can be saved in terms of water barrels (bbls). Meanwhile, it's possible to achieve a longer project life due to the slow depletion rate.


The design and hardware implementation of a permutation network architecture are examined. This is done by first defining a network and a setup procedure for it, and then coding the setup procedure into hardware at the register transfer level. The chip implementation of this network is also examined and found to be very feasible in a VLSI design environment. Furthermore, the modularity feature of the design approach makes it easy to build larger-size networks by using 16-input networks as building blocks. For example, by using three 16-input permutation networks it is possible to build a 32-input permutation network, by using three 32-b permutation networks it is possible to build a 64-input permutation network, and so on. Thus, a permutation network with a large number of inputs can easily be constructed using 16-input permutation networks, each of which can be housed in a VLSI chip. For example, a 1024-input permutation network can be built by using 729 16-input permutation networks.<<ETX>>


We describe the effective lagrangian approach to the color superconductivity. The effective description that arises if one considers only the leading terms in the expansion for very high densities is particularly simple. It is based on a lagrangian whose effective fermion fields are velocity-dependent; moreover strong interactions do not change quark velocity and the effective lagrangian does not contain spin matrices. All these features render the effective theory similar to the Heavy Quark Effective Theory, which is the limit of Quantum ChromoDynamics for infinite quark masses. For this reason one can refer to the effective lagrangian at high density as the High Density Effective Theory (HDET). In some cases HDET results in analytical, though approximate, relations that are particularly simple to handle. After a pedagogical introduction, several topics are considered. They include the treatment of the Color-Flavor-Locking and the 2SC model, with evaluation of the gap parameters by the Nambu-Gorkov equations, approximate dispersion laws for the gluons and calculations of the Nambu-Goldstone Bosons properties. We also discuss the effective lagrangian for the crystalline color superconductive (LOFF) phase and we give a description of the phonon field related to the breaking of the rotational and translational invariance. Finally a few astrophysical applications of color superconductivity are discussed.


We perform stellar evolution calculations for stars in the mass range 1 . . . 3M⊙, including the physics of rotation, from the zero age main sequence into the TP-AGB stage. We calculate two sets of model sequences, with and without inclusion of magnetic fields. From the final computed models, we can accurately predict the angular momenta and rotational velocities of the emerging white dwarf for each sequence. While sequences including magnetic fields predict white dwarf rotational velocities between 2 and 10 kms−1, those from the non-magnetic sequences are found to be one to two orders of magnitude larger, well above the spectroscopic upper limit derived by Berger et al. (2005). We find the situation analogous to that in the neutron star progenitor mass range, and conclude that internal magnetic fields appear capable to reproduce the observed slow rotation of compact stellar remnants.


Objective:To evaluate hysteroscopy in the clinical diagnosis of postmenopausal bleeding.Methods:Retrospective analyzis was conducted in 56 patients of postmenopausal bleeding with hysteroscopy findings on from July 2004 to September 2006.Results:The reasons of postmenopausal uterine bleeding hemorrhage of the 56 cases after biopsy confirmed were:shrink endometrial bleeding and endometritis total of 29 cases(29/56,51.79%),endometrial hyperplasia in 4 cases(4/56,7.14%),endometrial polyps 11cases(11/56,19.64%),endometrial carcinoma in 6 cases(6/56,10.71%),submucosal uterine myoma 3 cases(3/56,5.36%).Conclusion:Hysteroscopic uterine cavity lesions,as a direct observation of the technology,superior diagnostic curettage and the B high grade phantom study diagnosis,which is the diagnosis and treatment of gynecological diseases indispensable and irreplaceable intrauterine methods.


Infected amniotic membranes, called chorioamnionitis, can cause fetal infection as a consequence of proximity. A retrospective cross-sectional study, 274 preterm infants born within a year were analyzed and placentas from each preterm infant were classified as positive or negative chorioamnionitis and in the records of preterm infants, those with early neonatal sepsis, perinatal asphyxia, respiratory failure, clinical and / or laboratory changes within the first 72 hours of life. The data showed that there was greater morbidity and mortality in preterm infants with positive chorioamnionitis.


Objective To explore the clinical effects of sitagliptin alone or its combination with metformin on the patients with type 2 diabetes registered on their first clinic/hospital visits.Methods Eightytwo patients with type 2 diabetes who diagnosed with oral glucose tolerance test (OGTT),insulin test and glucagons stimulating C-peptide test from May 2011 to February 2012 in our hospital were randomly divided into two groups:the patients in control group took sitagliptin alone (control group,n =41) and the patients in experimental group took sitagliptin combined with metformin (experimental group,n =41).Eighty-two patients,after the mission,were given diabetic diet and moderate exercise therapy.Taking sitagliptin 100 mg,1 times/d;combined with metformin groups given sitagliptin 100 mg/d,metformin 250 mg,3 times/d.Six months later,the major indexes comparing between before and after treatment of weight,body Mass Index (BMI),glycosylated hemoglobin(HbA1c),OGTT,fasting plasma glucose (FPG),2 h plasma glucose (2 hPG),fasting insulin (FINS),2 h postprandial insulin (2 hINS),fasting C-peptide and 2 h postprandial C-peptide levels were measured to research the changes during the treatments.Results After treatments,all the indexes were decreased significantly,and the BMI,HbA1c,FPG,2 hPG,FINS,2 hINS,fasting C-peptide and 2 h postprandial C-peptide in the group with sitagliptin united with metformin were significantly lower than the group with sitagliptin((27.4 ± 1.2) kg/m2 vs.(27.9 ±1.5) kg/m2,t =-2.812;(8.1 ±1.2)% vs.(8.8 ± 1.3)%,t =-2.953;(8.17 ±1.22) mmol/L vs.(9.22 ± 1.28) mmol/L,t =-4.940;(10.16 ± 1.68) mmol/L vs.(11.01 ± 1.62) mmol/L,t =-3.362; (9.22 ± 1.93) mU/L vs.(9.85 ± 1.59) mU/L,t =-2.212;(74.62±13.73) mU/L vs.(83.75 ± 13.12) mU/L,t =-5.235;(1.43 ±0.34) μg/L vs.(1.77 ±0.27)μg/L,t =-3.194; (6.80 ± 1.40) μg/L vs.(7.61 ± 1.64) μg/L,t =-4.480 ; P < 0.05).Conclusion Sitagliptin is useful to treat type Ⅱ diabetes,plays important roles in improving patients' quality of life and insulin resistance,control of blood glucose,reduce the family and the burden of social health,and the effect will be more better when united with metformin.

Key words:
Type 2 diabetes;  Insulin resistance;  Sitagliptin;  Metformin


scientific perspective. Social scientific analyses have tended to emphasize social bases of political cleavage, party organization, power and informal decision-making patterns, and the local sources of public policy variation. They have not dealt with national-local relations so directly as has research conducted under the rubrics of public law and public administration, the history of governmental institutions, and public finance. The first set of themes has been emphasized by social scientists, especially those oriented toward North America ; the second set has been more salient for legal scholars, historians, and institutional economists, more frequently working in European universities. But this dichotomy, only partially valid for the past, seems to be breaking down even more at present. This is clearly the case outside the US. It is increasingly true for studies of American communities 1. The vast scale of


The early stages of Co deposition on a silver electrode in ammonia medium were studied using cyclic voltammetry and chronoamperometry coupled with quartz crystal microbalance (EQCM) in ammonia solution. The results obtained by means of EQCM showed that during the initial stages of cobalt deposition a monolayer is formed on the substrate both in the underpotential and overpotential region, and this monolayer is formed at −600 mV and −980 mV. Once the cobalt deposition process starts, the growth is very fast making the investigation of the initial stages rather difficult. During this process, cobalt atoms transfer their two electrons through free species and not through cobalt hydroxide species adsorbed on the electrode as CoOH


OBJECTIVE:To explore the measures for protecting the interests of online drug purchasers (consumers).METHODS:Through questionnaire survey,the status quo of the online pharmacy in China was analyzed,and the measures for the protection of online drug purchases were put forward.RESULTS CONCLUSIONS:The problems existed in current online pharmacy in China manifested as confused online drug information,potential quality problems related to the source and distribution of online drugs,inadequate online counseling service of licensed pharmacists in some pharmacies,potential risks of disclosing privacy,and difficulties for consumers to maintain rights and interests after drug purchase.The protection on online drug consumers can be improved through cracking down illegal online pharmacies,establishing the quality assurance system for the drug delivery of online drug pharmacies,evolving the online licensed pharmacists' counseling service system and online protection of privacy and perfecting the dispute settlement mechanism occurred during online drug purchase transaction etc.


Microbiological quality control testing in breweries is essential for maintaining high product quality and should be performed routinely. The effects of microbial contamination, derived from organisms including bacteria, wild yeast and mould, can range from comparatively minor changes in beer flavour and fermentation performance to gross flavour and aroma defects, turbidity problems and reduced yeast performance. Further implications of batch contamination include significant financial loss and decreased consumer confidence. This review discusses current microbiology testing techniques and their limitations, then focuses on new developments and technologies for routine microbiological control testing. The adoption of new technologies such as proteomic fingerprinting by mass spectrometry would allow breweries to conduct more extensive microbiological analyses that are currently cost- and time-prohibitive, particularly for small breweries. Copyright © 2017 The Institute of Brewing & Distilling StartCopTextCopyright © 2017 The Institute of Brewing & Distilling


Prostatic inflammation is gaining increasing attention as a potential etiologic factor in prostate cancer, benign prostatic hyperplasia, lower urinary tract symptoms, and CPPS. This study was performed to address the need for a well characterized model of acute prostatic inflammation that may be used to study the effect of acute inflammation on epithelial and stromal cell proliferation, voiding behavior, and neurovascular physiology.


SECTION 1 VASCULAR LESIONS: Carotid Cave Aneurysms of the ICA. Giant Aneurysms of the ICA. Dorsal ICA Aneurysms. Anterior Communicating Artery Lesions. Basilar Bifurcation Aneurysms. Basilar-Superior Cerebellar Artery (BA-SCA) Aneurysms. Basilar Trunk Aneurysms. Vertebral Artery Aneurysms. Arteriovenous Malformations SECTION 22 TUMORS: Cavernous Sinus: a Philosophy and Anatomy. Surgical Strategy in Tumors Involving the Cavernous Sinus. Surgical Approaches to Clival Lesions. Anterior Skull Base Tumors. Surgery for Acoustic Neuroma. Anterior Clinoidal Meningioma. Surgical Management of Giant Pituitary Tumors. Surgery of Intra-Axial Brain Stem Tumors. Chordomas: a Clinical Review. Juvenile Nasopharyngeal Angiofibromas. Approaches for Trigeminal Neurinomas SECTION III MISCELLANEOUS: Craniovertebral and Spinal Stability. Tumor. Obstructive Hydrocephalus. Reconstruction of the Skull Base. Computers in Neurosurgery


– The purpose of this article is to examine growth expectations and factors influencing growth of side activities in rural areas., – Data were collected in the rural areas of 36 Dutch municipalities by means of a detailed survey. This resulted in 260 response cases. The analysis consists of a descriptive account of respondents' intentions to expand a side activity and a logistic regression explaining growth expectations of these activities., – The main conclusion is that although growth is not expected in a large number of side activities, there is a group of owners who clearly aspire to expand the scale of their activities. Their personal aspirations and aspirations for economic well‐being are the most common motivations. These characteristics also have a bearing on the future growth of side activities and consequently their impact on rural development., – Since this article examines growth expectations and not actual growth, the findings cannot be interpreted directly in terms of economic impact on rural development., – Scholars and policy makers have paid little attention to side activities in rural areas and specifically to their growth potential. This article enhances our understanding of the growth expectations of those who carry out side activities and shows the potential of such activities in diversifying and revitalizing rural areas.


With more emphases on economic growth and greater differences emerging from regional economy,we should concern ourselves more with the harmonious social development of China.The human development index system,which is composed of human health,level of education and life quality,is put forward by United Nations Development Program.It is adopted and improved in this paper.The results show that 1):Nationally speaking,great human development has been made in China.In 2005,human development index(HDI)of China is 0.755,which is higher than the world average,ranking the 85th in 177 countries and regions around the world and belonging to the middle development level.However,there are significant differences between China and countries with higher level of human development,and GDP per capita is the key factor for China to improve in human development;2)At provincial level,the human development in 2000 greatly varied in different areas.It tended to be higher in the east areas than in west and only metropolises as Beijing,Tianjin and Shanghai reached a high level of human development;3)At the level of counties,over four-fifth of all counties surveyed stood at a medium level of middle human development in China and there are obvious differences between one county and another.In the last part,the paper put forward proposals and measures for China to improve human development,which can provide a theoretical and practical basis for constructing a harmonious society.


Prediction of Critical Heat Flux at high mass quality is important for the safety of once-through steam generator and the reactor core under accidental conditions.Based on the theory for droplet entrainment,droplet deposition and liquid film evaporation,the film thickness and film mass flow rate dis-tribution along axis are calculated at vertical upward round tube.The dryout emerges at the point where the film is depleted due to the balance of entrainment,deposition and evaporation.The theoretical CHF values are higher than that of experimental data,with error within 30%.


The properties of PH-55A, PH-55B, and PH-55C stainless steels are tabulated and compared with other stainless steels. These metals offer high strength without severe cold working, and they are corrosion and abrasion resistant. (T.R.H.)


This paper analyzes the constraint factors of the gate providing service for aircraft, and sets up a mathematic model for the gate assignment. Then, the occupy sequence and time were respectively calculated with Memetic algorithm and Greedy algorithm.Finally, compared with Genetic algorithm, the feasibility and efficiency of Memetic algorithm for gate assignment are validated with an example, which is based on the data of Pudong airport.


Fatty acid (FA) composition of B. cereus sl strains belonging to the 7 phylogenetic groups. This file contains the raw FA composition data of the B. cereus sl strains used to generate Table 1 and Figure 1.


This article illustrates the difficulty of replicating results in the area of sports economics. This article gives three different examples that seem straightforward, but are actually quite difficult to replicate. Furthermore, the evidence suggests that the discrepancies are not due to human error. It is argued that the differences in results are due to differences in computing power over time, differences in statistical programs, or slight differences in available data. This gives evidence that researchers should be somewhat skeptical of any single empirical study.


Background: Oral health is often overlooked, but oral health is an unseparated integral part of general health. Some of factors that are influence oral health are knowledge, attitudes/behaviour, and maintenance behaviours. Pesantren is a boarding school dormitory where students are supervised by few dorm caregivers. This causes overlooked condition of individual health care. Purpose: This research aims to know relations of knowledge, attitudes, and oral healthcare behaviours of oral hygiene status of students of Junior High/MTs PondokPesantrenPutriUmmulMukminin students. Method: This study is an analytical observational study with cross sectional study design. Sampling technique is done with using cluster random sampling. This research conducted on students of class VIII of Junior High/MTs by giving questionnaires that are relate to knowledge, attitudes, and oral healthcare behaviour then examinating their oral hygiene using Oral Hygiene IndexSimplified (OHI-S) examination. Results: There were 97 respondents. 96 respondents (98,96%) had good knowledge and 1 respondent (1,03%) had average knowledge. 95 respondents (97,93%) had good attitudes in taking care of their oral health and hygiene, while 2 respondents (2,06%) had average attitudes. 76 respondents (78,35%) have done good oral healthcare behaviours, while 21 respondents (21,65%) were in average level of oral healthcare behaviours. In OHI-S examination, 55 respondents (56,70%) were goodcategorized, and 42 respondents (43,29%) were average-categorized. Chisquare analysis result between actions and oral hygiene showed p value = 0.0427 (p<0.05). Conclusion: There is a significant relation between behaviour and status of oral hygiene. When the behaviour category is average, OHI-S category is alsoaverage.


[Abstract]: [The authors] open this chapter with a brief description of a young Australian Aboriginal
student's first year at University. Her story is typical of the experiences of many Indigenous
students attempting to come to grips with life away from home in a competitive higher
education environment. [The authors] use her experiences as the basis for exploring a number of
themes that they feel have an impact on the academic success of Indigenous students: a) lack
of career knowledge among Indigenous students; b) the mismatch between what Indigenous
students expect to find at University and what they actually do find; c) mismatches between
the predominantly collectivist values held by Indigenous students and the more
individualistic values that predominate in Western university settings; d) external pressures
that make study difficult; and e) the lack of adequate preparation for the cognitive demands
of University study. [The authors] conclude that the last of these themes has the greatest immediate
impact on performance but that lack of preparation can be understood only in the context of a
wider range of cultural variables.


Aiming at finger-vein identity authentication requirements,a near-infrared light source controllable finger-vein image acquisition system is designed based on single light source and reflection mirror. The impact of LED light source position and angle on vein image quality is studied,finger-vein authentication method based on image quality assessment,is proposed and verified by actual measurement method. Experimental results show that the proposed vein image acquisition system can obtain vein image of equal quality with traditional front light source acquisition has higher authentication passing rate of 98. 8 %,and easy to use for user.


The development and application of data mining technology puts forward new requirement to knowledge management in information era. Intelligent knowledge is the valuable knowledge that comes from data mining technology, and has the intelligent features such as memory, recognition, self-updating, disappearance etc after the transaction by man-machine interaction. On the basis of analyzing the goals and layers of intelligent knowledge management, this paper studies the implementation model of intelligent knowledge management from the aspects of its cultivation, expression and storage, audit and logic mechanism etc. It will afford new perspective for research on knowledge management.


This paper examined the existing literature on the established scale on 'Employer Attractiveness' (Emp At) and other aspects around different elements and further conducted a qualitative review to explore the other facets. The literature review and qualitative research revealed several dimensions related to EmpAt. The earlier studies have been carried out more than 10 years ago, thus leaving room for re-examination in reference to the current times, businesses and the so called newer aspirations. The changing technology, urbanization, aspirations, industries and globalization have created new thought processes in the mind of prospective employees thus creating gaps in the supply and demand of the talent in different countries. This makes 'Employer Attractiveness Scale' vital to look at. The study further augmented by the in-depth qualitative inputs from mid to senior level executives from industry were looked at to discover the different dimensions and attributes that comprehensively constitute the EmpAt. The study is aimed to develop a new scale finally that will help various organizations understand and measure the important aspects, constructs that prospective employees look at while considering how attractive a certain employer is.


This study aimed to examine the difference in expression of matrix metalloproteinases (MMPs) in ameloblastoma and other benign tumors or normal tissue of the jaw, and ameloblastic carcinoma, and to investigate the correlation of expression of MMPs with patient prognosis.


The studies of Edlbacher (1) and many other investigators on the breakdown of histidine by liver extracts and other isolated systems would lead one to expect glutamic acid to be the principal primary metabolite of histidine in vivo. To explain this conversion, Edlbacher proposed a scheme whereby the imidazole ring of histidine is cleaved, to give the 5-carbon skeleton of glutamic acid directly. Other investigators, e.g. Oyamada (2), proposed a radically different mechanism, involving formation of urocanic acid as the first step and its subsequent cleavage to glutamic acid, the amino nitrogen of which is derived from the ring nitrogen of histidine. That the latter mechanism was operative in isolated systems (e.g. Pseudomonas jtuorescens extract) was shown with N15 and ring C14-labeled histidine by Tabor et al. (3). Working with intact animals, Crookshank and Clowdus (4) and D'Iorio and Bouthillier (5), by the use of normal and of carboxyl-labeled histidine, obtained results which seemed to indicate that histidine is not transformed to glutamic acid. To shed some light on this apparent discrepancy, histidine was synthesized with a comparatively high level of radioactivity in the a-carbon. Glutamic acid, isolated from the protein of a rat dosed with the labeled compound, was found to be strongly radioactive. The radioactive glutamic acid was partially degraded to demonstrate that the a-carbon of histidine becomes the y-carbon of glutamic acid.


InGaAsP-InP laser bars with an emission wavelength of 1.73 /spl mu/m have been fabricated using compressively strained multiple-quantum-well (MQW) separate-confinement heterostructures (SCH). One-cm-wide, 0.7-fill-factor, diode bars are bonded onto Si microchannel heatsinks and stacked into a two-dimensional (2-D) laser array, 16 W of continuous-wave (CW) power was produced from a 1-cm bar and 200 W of peak power was generated from a 10-bar array with an emitting aperture of 1 cm/sup 2/.


ABSTRACT In this article, we negotiate the tension of Lizzo's embodiment and the work she is forced to perform to appease and mollify both thin and non-Black audiences. As a Black fat rapper, singer, dancer, and performer, Lizzo at once disrupts the normative image of a performer and becomes a commodified representation of body positivity. Her self-love messaging undoubtedly touches a broad fan base who look to her for guidance and inspiration. But how is she taken up by audiences dissimilar to her? Lizzo's body-positive politic is presented as being particularly interested in disrupting body terrorism, while some audiences perceive it as a neoliberal model of self-love, failing to challenge systems. We consider ways in which Black fat bodies are consumed and used for their utility, while broader relationships to other Black fat people remain unchanged. We map selections from Lizzo's creative output in 2019 to demonstrate racialization and fat embodiment intertwined in her performances, leading to the necessary coalition that fat activism must adopt.


The industrial economy in developed countries is transforming into a new economy of the information age.For nearly every company, complex, often radical and dramatic transformation needs are created. Executiveprograms in continuing education, however, are usually focussing on business administration rather than onbusiness transformation. For a successful management of change projects, it is necessary to integrate skills fromdifferent areas: While general management skills are needed for strategic vision, organizational development,and process analysis, more technical skills are necessary to assess business potentials of IT innovations and tomanage the development of appropriate information systems. Change management and other soft skills are aprerequisite for successful leadership in transforming organizations. The post-graduate executive programMaster of Business Engineering has been developed to integrate knowledge from all of these areas, therebyenabling high potentials to succeed in transforming industrial companies into the information age. This paperoutlines theoretical foundations and describes current curriculum as well as experience and future plans.


Abstract Background A number of intrinsic (age, gender, physical comorbidities, genetic factors, and ethnicity), and extrinsic factors (diet, concomitant medications, alcohol use, and smoking) influence an individual's response to psychotropic medications. Data suggest that ethnicity may affect medication efficacy, tolerability, and safety through different pharmacokinetics and pharmacodynamics. Asians have been found to have a high frequency of reduced function of CYP2D6 allele (CYP2D6*10), which contributes to the slower metabolism of some medications compared to other ethnic groups. The previous study has shown East Asians appear to have a clinically relevant decrease in clozapine clearance compared with Caucasians. This review will explore the magnitude of the impact of ethnicity, especially the East Asian population on psychotropic medications such as atypical antipsychotics. Objective To understand the efficacy, safety, and tolerability of atypical antipsychotics in East Asian ethnicity. To emphasize the importance of ethnicity in clinical practice while offering/prescribing atypical antipsychotic medications. Discussion Several previous studies reported the diverse response to the antipsychotics among different ethnicities secondary to differences in pharmacokinetics and pharmacodynamics. One study revealed White Europeans may require higher doses of therapeutic antipsychotics than Asians and Hispanics. Aripiprazole in Asians had a relatively higher rate of akathesia, and a significantly increased risk of tremor compared to placebo. A significantly increased risk of weight gain and fasting total cholesterol from olanzapine were observed in Japanese patients. Olanzapine was also associated with somnolence and dizziness. Quetiapine XR was associated with a significant increase risk of somnolence and dizziness in Chinese patients. Conclusion It is indicated from previous studies antipsychotics respond in various ways in different ethnicity in terms of metabolism, clearance, and adverse effects. Further research could be beneficial on what is clinically most effective dosing of different antipsychotics among different populations including East Asians. Funding No funding


Good positioning accuracy and coverage are important evaluation criterion for Wireless Sensor Network localization algorithm. DV-HOP is one of the classical range-free localization algorithms, which has good adaptivity and flexibility when node density (ND) and anchor density (AD) are both smaller. However, DV-HOP doesn't consider asymmetric links' influence in heterogeneous network, which is analyzed and proved as the main reason for poor positioning accuracy in DV-HOP. Then a Range-Free Localization Algorithm in Wireless Sensor Network with Asymmetric Links (RLAAL) is proposed, whose kernel mechanisms are Neighbor Discovery Algorithm (NDA) and Least Hops Acquiring Mechanism (LHAM). Every Node uses NDA to find all neighbors and uses LHAM to find least hops to Anchor nodes. Simulation results show that RLAAL can reduce asymmetric links' influence and have better positioning accuracy and coverage than DV-HOP.


The invention discloses a control method of a birotor-structure variable-speed constant-frequency wind power generation system, belongs to the technical field of wind power generation system control, and aims to solve the problem that an existing birotor wind power generation system can only work efficiently at a low wind speed. A wind turbine is started to rotate when the wind speed of an environment of the wind turbine locates reaches a cut-in wind speed, a gear transmission mechanism is driven to work, the wind speed of the environment of the wind turbine is detected, the rotating speed of an adjustable-speed motor is controlled when the wind speed of the environment of the wind turbine is lower than a rated wind speed, a power generator is enabled to reach a power grid connection frequency, the rotating speed of the adjustable-speed motor is changed when the power generator is connected with a grid, and then the rotating speed of an output shaft of the wind turbine is changed so as to realize tracking control at the maximum power; when the wind speed of the environment of the wind turbine is larger or equal to the rated wind speed, the adjustable-speed motor is controlled to be in a torque control state, so that the power generator is enabled to work in a rated manner, and output power is fed to the power grid by the adjustable-speed motor via a frequency converter. The control method is used for controlling the birotor-structure variable-speed constant-frequency wind power generation system.