This paper examines the transport of a chemically reacting nanofluid in a
 porous medium between two rotary disks with Cattaneo-Christov?s heat flux.
 The non-linear ordinary differential system formed under Vonn Karman
 transformation of a non-linear partial differential system is solved via a
 shooting method with MATLAB bvp4c. The nanofluid thermodynamics profiles
 with variation in physical properties of thermal relaxation time, thermal
 radiation, porosity, and chemical reaction are observed. Axial, radial, and
 tangential velocities are found to be increasing functions of porous
 medium. A decrease in the fluid temperature is perceived as thermal
 radiation and thermal relaxation increase since more heat can be transported
 to neighboring surroundings. The concentration is enhanced with intensified
 Cattaneo-Christov?s thermal relaxation but it oscillates with reacting
 chemicals. The rotary disks bound the oscillating nanofluid from downward to
 up-ward directions and vice versa. The axial velocity represents the change
 in force due to porosity and radial stretching of the disks.


Objective To determine whether extremely preterm (EP) birth exerts persisting effects on parents in early adolescence. Design Cross-sectional survey conducted between March 2017 and October 2018. Setting Evaluation of a longitudinal population-based birth cohort in England at 11 years of age (EPICure2@11 Study). Participants Parents of EP (<27 weeks of gestation) adolescents and control parents of term born (≥37 weeks of gestation) classmates of similar age and sex. Main outcome measures The Parenting Stress Index Short Form (PSI-4-SF) and the Short Form Health Survey (SF-12v1). Results The 163 EP and 125 comparison respondents were most commonly mothers in their mid-40s. EP parents reported higher total parenting stress scores compared with controls, overall (adjusted difference in means: 14 (95% CI 9 to 20)) and after exclusion of moderate and severe child disability and multiples (9 (95% CI 3 to 15). Average physical and mental health-related quality of life scores were similar in the two groups (adjusted difference in means physical health: −2 (95% CI −4 to 1) and mental health: −1 (95% CI −4 to 1)). Among EP parents, 12% (20/164) reported the combination of high parenting stress and low mental health scores. With increasing child age, parenting stress scores for preterm parents were lower in contrast to controls who reported increasing parenting stress. Conclusions In early adolescence, compared with parents of term-born children, EP parents experience increased levels of parenting stress that are particularly high among a proportion of parents and associated with lower mental health-related quality of life. Practitioner awareness of this continuing risk throughout childhood is important to support parental abilities and well-being.


The structure of amorphous Fe100-xBx alloys is described by a stochastic arrangement of two structural components. compared with existing quasi-crystalline and two-phase models important improvements are introduced: (i) the heterogeneity of the system is characterised quantitatively by correlation functions for arbitrary volume fraction of the structural components; (ii) the deviation of the atomic structure in the vicinity of the boundary between the two structural components from the regular structure of the two components is taken into account by an approximation; (iii) both the atomic correlations of the single structural components and cross correlations between them are considered. The authors derive analytical expressions for partial pair distribution functions, cluster dimensions and other structural quantities. The partial pair distribution functions for Fe100-xBx are evaluated assuming the structural components to be given by BCC Fe and BCT Fe3B, and cluster dimensions are about 1 nm. The FeFe (BFe) model distribution agrees well with the experimental results of Nold et al. up to 1.3 nm (0.5 nm). The BB model curve shows a series of well separated coordination shells in contrast to the experimental one.


For opening and shutting function, door has some hardware such as hinges and the locks. The folding mechanism of hinges represent mobility, and the lock means stability. The opening and shutting door-the mobility-could be interpreted the movement from flat state to three-dimensional structure. The folding mechanism also would be understood variable feature to the space. This study focus on the Folding Furniture which adapted the good point of hinges to make efficient use of the space. The folding furniture presented in this study has not only artistic meaning which expand and apply structural function of hinges, but also flexible reanalysis on the environment and the space which change with social, economic and cultural trend.


The study was performed to check the adequacy of parenteral nutrition prescription to current recommendations in nonsurgical inpatients. To check this adjustment, we carried out a retrospective study in 2012 of all patients admitted to the internal medicine and Intensive Care Unit (ICU). For each patient with Parenteral Nutrition (PN) we revised if they could have been a candidate for Enteral Nutrition (EN) or otherwise only should continue with PN, based on current recommendations and according to their diagnosis. Along the studied period, we reviewed 30 patients in total with parenteral nutrition and based on the above criteria, 18 of these patients were candidates for enteral nutrition, which represents 60% of all the studied patients. This discrepancy is probably due to the outdated methods of the physicians and their approach in the adoption of the new recommendations, issue that we should encourage


This paper presents an algorithm to assist in automatic selection of proper values of geometrical and electrical parameters of an oscillator for oscillation condition satisfaction. The algorithm is described in order to assist and hasten the process of microwave oscillator design. The algorithm's general logical structure is described.


The analysis of multitemporal very high spatial resolution imagery is too often limited to the sole use of pixel digital numbers which do not accurately describe the observed targets between the various collections due to the effects of changing illumination, viewing geometries, and atmospheric conditions. This paper demonstrates both qualitatively and quantitatively that not only physically based quantities are necessary to consistently and efficiently analyze these data sets but also the angular information of the acquisitions should not be neglected as it can provide unique features on the scenes being analyzed. The data set used is composed of 21 images acquired between 2002 and 2009 by QuickBird over the city of Denver, Colorado. The images were collected near the downtown area and include single family houses, skyscrapers, apartment complexes, industrial buildings, roads/highways, urban parks, and bodies of water. Experiments show that atmospheric and geometric properties of the acquisitions substantially affect the pixel values and, more specifically, that the raw counts are significantly correlated to the atmospheric visibility. Results of a 22-class urban land cover experiment show that an improvement of 0.374 in terms of Kappa coefficient can be achieved over the base case of raw pixels when surface reflectance values are combined to the angular decomposition of the time series.


1. Five oligotrophic clear-water lakes on the Faroe Islands were studied during August 2000. Algal and bacterial production rates, community respiration, and CO2 saturation were determined. In addition, we examined the plankton community composition (phytoplankton and heterotrophic nanoflagellates) and measured the grazing pressure exerted by common mixotrophic species on bacteria. 2. High respiration to primary production (6.6–33.2) and supersaturation of CO2 (830–2140 μatm) implied that the lakes were net heterotrophic and that the pelagic heterotrophic plankton were subsidised by allochthonous organic carbon. However, in spite of the apparent high level of net heterotrophy, primary production exceeded bacterial production and the food base for higher trophic levels appeared to be mainly autotrophic. 3. We suggest that the observed net heterotrophy in these lakes was a result of the oligotrophic conditions and hence low primary production in combination with an input of allochthonous C with a relatively high availability. 4. Mixotrophic phytoplankton (Cryptomonas spp., Dinobryon spp. and flagellates cf. Ochromonas spp.) constituted a large percentage of the plankton community (17–83%), possibly as a result of their capacity to exploit bacteria as a means of acquiring nutrients in these nutrient poor systems. (Less)


A three color laser fluorometer has been developed for field work operations. Using two tunable dye lasers (excitation wavelengths at 440 nn and 530 rm), broadband wavelength optical filters were selected to obtain maximum fluorescence sensitivity at wavelengths >675 rm (chlorophyll) and 575 rm (+15 im (phycoerythrin)). The laser fluorometer permits the measurement of phytoplankton piguents under static or flowing conditions and more closely resembles the time scales (ns) and energy levels (mW) of other laser-induced fluorescence instruments. 1. INIEQDUCnON The applications of fluorometry to studies of the hydrosphere are becoming extremely sophisticated. Early instruments utilized lamps vMch provided excitation wavelengths at a nunber of discrete lines and broadband glass absorption filters to isolate fluorescence emission specific to the molecule of interest. With few changes to this basic instrument design, studies of water circulation and dispersion using fluorescent tracer dyes1; the distribution of phytoplankton chlorophyll in vitro 2'3 and in vivo4 ; and dissolved organic matter 5 have become routine. With the addition of monochromators in place of the glass filters for wavelength selection, fluorescence spectroscopy has also been applied to these studies and others such as hydrocarbon identification in seawater 6. Improvements in the sensitivity and selectivity of fluorometry have naturally led to the use of lasers, both pulsed and continuous wave. Applications of laser fluorometry range from the airborne oceanographic lidar (AOL) system 7 to flow cytometric measurements of single cell fluorescence 8'9'10. Comparisons are often made of data obtained with a conventional field fluorometer and one of the more sophisticated ' fluorometers' even thougji the excitation energy and time scales differ by orders of magnitude. Our intent in the present work was to fabricate a field fluorometer using compact pulsed dye lasers vMch would more closely resemble the time scales (ns) and energy levels (mW) of other laser induced fluorescence instruments. Measurements can be made using either a static or flow througji cuvette.


Synopsis The effect of the inhomogeneous hear strain through the thickness of rolled sheet on the recrystallization behavior and texture formation has been investigated. Type AISI 304 stainless steel sheets were rolled to various reductions at temperatures ranging from 800N 1100°C at a rolling speed ranging from 15N 37 m/s without lubrication. The rolled specimen was quenched at an interval of 3.5-'250 ms after rolling. The redundant strain by friction produces a severely sheared region beneath the surface. A band of extremely fine grains is formed by dynamic or metadynamic recrystallization above a critical reduction which is dependent on rolling temperature. The deformation texture consists mainly of {001}<110>, {111}<110> and {112}< 110> in the severely sheared region, and mainly {110}< 112> in the midthickness. The recrystallization texture in severely sheared region retains the deformation texture except for the {001}<110> component, and is unchanged in the subsequent annealing. Static recrystallization occurs in the region other than severely sheared region by holding or subsequent annealing after rolling. The texture randomizes with progress of the static recrystallization.


Introduction:
 Acute lymphoblastic leukemia (T-ALL) is an aggressive hematopoietic malignancy in children and adolescents that is associated with high rates of treatment failure and early relapse. T-ALL patients frequently harbor NOTCH1 activating mutations as the driving oncogene in this disease. A multitude of strategies preventing NOTCH1 cleavage and activation, such as Gamma-secretase inhibitors (GSIs) have been developed. Despite promising pre-clinical data, the rapid development of Notch1 inhibitor resistance in early clinical trials, prevented the translation of these inhibitors into the clinical setting. In previous work, our group demonstrated that T-ALL resistant to NOTCH1 inhibition carry altered epigenetic states conferring unique dependency on epigenetic modifiers, such as BRD4. The goal of this study was to study enhancer rewiring in Notch1 inhibitor resistant T-ALL in vivo and its relationship to apoptotic priming.
 Methods:
 After reaching 5% of circulating leukemic blasts, five established T-ALL PDX models with aberrant NOTCH1 expression were divided into to two treatment groups each (8 mice per group). 1 group received the Notch inhibitor DBZ (Dibenzazepine; 10 μM/kg intraperitoneal every other day) and the other group was treated with vehicle. Short-term effect of DBZ in vivo was assessed after 1 week of treatment, when 3 mice per group were sacrificed and leukemic blasts were isolated from spleen and bone marrow. The remaining 5 mice were monitored for disease burden (by flow cytometry staining for human CD45+) and followed for survival. After reaching moribund state, animals were sacrificed, spleens and bone marrows were collected and prepared for further analyses.
 To assess DBZ efficacy in vivo, the presence of active NOTCH1 (ICN1) in spleen and bone marrow was analyzed by Immunohistochemistry analysis (IHC).
 Enhancer landscapes were identified by chromatin-immunoprecipitation followed by sequencing (ChIP-Seq) for Histone 3 Lysine 27 acetylation (H3K27ac). A custom computational pipeline that incorporates algorithms for demultiplexing, alignment, normalization, peak calling, and computation of signal intensities within peaks was used to call differential peaks and intersect with RNA-sequencing results.
 BH3 profiling was performed on leukemic blasts isolated from spleen to measure overall mitochondrial priming and to identify anti-apoptotic dependencies.
 Results:
 In four out of five T-ALL PDX models, IHC analysis of spleen and bone marrow demonstrated a drastic downregulation of active NOTCH1 upon DBZ treatment, validating the efficacy of the used inhibitor. Weak ICN1 staining that remained unchanged upon DBZ treatment, was observed in 1 of the models, resulting in the exclusion of this strain from further functional analysis.
 Survival analysis of the four T-ALL PDX models expressing ICN1, revealed the presence of two Notch inhibitor sensitive and two refractory strains. The latter strains developed DBZ resistance rapidly after starting treatment (less than 10 days). One sensitive strain eventually developed resistance, while the second showed long-term disease control. Transcriptional profiling (bulk RNA-seq) of Notch inhibitor refractory strains versus sensitive identified the intrinsic apoptotic pathway as one of the most deferentially deregulated GSEA signatures.
 H3K27ac ChIPseq analysis at pretreatment (baseline), showed increased signal intensity of H3K27ac peaks at BCL2 and MCL1 enhancers in the refractory strains compared to sensitive. Upon DBZ treatment, while the enhancer state in refractory T-ALL remained unchanged, in the sensitive strains the signal intensity of H3K27ac peaks within the BCL2 and MCL1 loci decreased. Mitochondrial BH3 profiling at baseline demonstrated BCL-2 dependency (measured via BAD peptide) in sensitive strains and MCL-1 dependency (measured via MS1 peptide) in refractory strains. Upon DBZ treatment, sensitive strains showed a decrease in BCL-2 dependency and compensatory switch to MCL1-dependency, while dependency profile remained unchanged in refractory T-ALL.
 Conclusions:
 Our results suggest that enhancer rewiring near anti-apoptotic genes is critical for Notch inhibitor resistance. Combining BH3 profiling with enhancer profiling may allow to predict drug responses in vivo and may contribute to the identification of novel therapeutic targets for combination therapy in resistant disease.

 Letai: Zeno Pharmaceuticals, Vivid Bioscience, Flash Therapeutics, Dialectic Therapeutics: Membership on an entity's Board of Directors or advisory committees, Other: Cofounder or Advisory Board member; AbbVie, AstraZeneca, Novartis: Consultancy, Research Funding. Weinstock:Celgene: Research Funding. Lohr:T2 Biosystems: Honoraria; Celgene: Research Funding.


The Northern Pole's polar ice is melting at an alarming rate due to climate change, significantly impacting the region's strategic landscape. The potential for economic growth and increasing security competition has led Russia, China and the US to ramp up their politico-military activities in the region. This research paper uses a qualitative method that explores the changing geopolitics of the region through a structural realist approach to examine the strategic interests and opportunities of these three countries in the Arctic. The study sheds light on how climate change has affected the region's geopolitical and geostrategic effects and how these countries compete for influence in the area, leading to mounting concerns and policy shifts. The paper shows how Russia takes a realist approach; China enhances its influence through a developmental approach, while the US tries to increase its power to counter the influence of Russia and China in the region. Additionally, the paper explains how the interplay of interests in the region is associated with the offence-defence balance and security dilemmas resulting from the neorealist behaviour of these states.

Bibliography Entry
Mushtaq, Shireen, Uswa Sharif and Rida Fatima. 2023. "Strategic Opportunity, Security Dilemma and the Interplay of Interests: Russia, China and the US in the Arctic Region Since 2014." Margalla Papers 27 (1): 67-81.


This paper presents some results from student teachers of basic education with an emphasis in mathematics, in the course of Teaching Geometry, guided by the study of rigid motions such as translations and reflections, and compression transformations graphical representations of a system Cartesian coordinates in a real plane, with emphasis on the study of the


Hunn raises some interesting points.1 He asks the General Medical Council about "the sort of medical workforce the UK deserves." The answer is straightforward: UK patients deserve doctors who provide a high standard of care, whether they trained in this country or abroad, and we are determined to play our part in driving up standards. …


Three clinical cases of patients admitted in "Dr. Juan Bruno Zayas Alfonso" Teaching General Hospital in Santiago de Cuba due to the suspicious presence of cerebral aneurysms are described, keeping in mind the neurological manifestations they presented. By means of the studies of magnetic resonance and angiographic resonance carried out, the images of the vascular lesion were observed, which were confirmed by carotid angiography.


I N RED clover, the number of leaflets per leaf is usually three. Occasionally, however, an increased number, ranging from 4 to 12 leaflets, is observed. 8 Similar deviations are known in other trifolium species, e.g. Trifolium reDens , T. hybridum, and T. incarnatum, but have not been reported in Medicago ~ or Melilotus. Polyphylly may be induced by environmental effects such as mechanical or frost damage, a or luxury nutrition. 5 On the other hand, genetic control of the character cannot be Tab:le 1--Relationship of progenies and proportion of polyphyllid plants.


Abstract : This report describes the design, fabrication, and testing of the IWARP display module. The display module is a custom circuit board designed specifically for the Intel iWarp processor. Software written during this development enables the board to generate video signals to drive a high- resolution color display, with images processed within the iWarp processor array. The module contains 4 megabytes of VRAM which will hold images of user- determined pixel depth and size. Image data are converted to analog video signals by the Inmos G364 color video controller chip. Image sizes can range from 1024 by 1024 24-bits-per-pixel true-color images to 1-bit-per-pixel monochrome images. As part of this development, several iWarp programs have been developed to aid in the use of the display. To the image processing application developer, data can be displayed with a simple one-line subroutine call. High- resolution displays, iWARP


The article proposes a solution to the problem of development, research and mathematical modelling of the current source elements for the mechanized welding in a shielding gas environment. The author proposed, described and presented on a mathematical model a current source that makes it possible to excite and stabilize the arc at any welding currents without an oscillator as an independent or built-in unit. It is shown that a high-voltage pulsed source can be formed in the structure of an inverter power source for the arc welding in a shielding gas environment. The results are confirmed experimentally on prototypes. Research, calculations and modelling were carried out using the Simulink packages of the MATLAB R2021b system and the MAPLE R2021 package.


Landscape-basin systems are the optimal territory states of the mountain regions stable development organization. The problem may be solved by using different methods and different scientific trends and investigations. The paper studies the landscape-basin organization of mountain polyethnic territories on the Daghestan republic.


The purpose of this study is to look into research trends concerning Late Talker Children in international and Korean journals. A total of 89 articles were selected. These papers were reviewed in terms of the time of publication, research type, developmental period of subjects and also dependent variables. The main results of this study were as follows: First, Korean studies were taken from the mid 2000s, whereas international studies were taken from the mid 1980s. Second, most of the Korean and international studies consisted of comparative studies of normal children. Third, the most common dependent variables are language variables and there are also a lot of studies on symbolic play researches of Late Talker Children. Fourth, the studies in international journal were various developmental periods ranging from infancy to adolescence, whereas the study in Korean journals were limited to infancy. The implications for future research in Korea were discussed.


By the means of documentary,investigation and video statistics,etc,the author compare the result,movement difficulty and performance of Chinese teams with other powerful teams in the recently three international and internal Gymnastics Competition.The result shows that the strength of Chinese man's team still keep ahead,but there is a large gap on Chinese Woman's team.The Chinese team has many all round gymnasts,but they all have the weak event.Chinese gymnasts have the ability to win the golden medal in individual event.They need to improve their stability of movement and psychological quality.


¨This thesis focuses on evaluating the dual-modal Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) capabilities of contrast agents. For such purposes a gadolinium based contrast agent ...


The single pulse (SP) – pulsed laser polymerization (PLP) technique has been applied to measure kt /kp, the ratio of termination to propagation rate coefficients, for free-radical bulk homopolymerizations of methyl acrylate (MA) and dodecyl acrylate (DA) between 10 and 50°C at pressures from 10 to 2 500 bar. kt /kp is obtained from experimental monomer concentration vs. time traces that are determined via time-resolved (μs) near infrared monitoring of monomer conversion induced by single excimer laser pulses of about 20 ns width. With kp being known from PLP–SEC experiments, chain-length averaged kt is immediately obtained from kt /kp. For MA, kt remains constant up to about 15% monomer conversion and clearly decreases upon further polymerization. For DA at pressures of 100 bar and above, a plateau value of constant kt is observed up to about 60% monomer conversion whereas at lower pressure, e. g. at 10 bar, kt slightly increases in the very initial conversion region, but also exhibits a plateau kt value at moderate and high conversions. The occurrence of such plateau kt values and their pressure and temperature dependence are consistent with the view that plateau regions of kt are best understood in terms of diffusion control via segmental mobility.


:  Singapore is placed in the Outer Circle of the Kachru's Three Circles Model, and has over the years developed an English which is uniquely Singaporean. This paper argues that in order to understand the ways in which Singapore English is developing its own standards and ways of speaking, a new model needs to be developed that takes culture, capital and identity into consideration. This socio-cultural perspective is one grounded in an understanding of the dualistic role of English in Singapore both as a global language and a local language. It is argued that this duality is consistent with the cultural identity of Singaporeans who negotiate fluidly between two divergent orientations – that of the global citizen and the local Singaporean. The paper explains how a culturally focused model which examines the identities of Singaporean speakers is able to provide a finer-grained and thus more explanatorily adequate account of Singapore English than previously proposed models, in particular, the diglossic analysis.


Summary
In bay snook (Petenia splendida) larvae the histological development of the digestive system and swim bladder, and their relative timing of differentiation were studied from hatching to 45 days post-hatch (dph) at 29°C. Newly hatched larvae showed a simple digestive tract, which appeared as a straight undifferentiated tube lined by a single layer of columnar epithelial cells (future enterocytes). The anatomical and histological differentiation of the digestive tract and accessory glands was a very intense, asynchronous process, proceeding from the distal to the anterior part. The intestine was the first region to differentiate (9 days post-hatch – dph, 6.5 mm SL), and the oesophagus the last (21 dph, 8.4 mm SL). At the onset of feeding, the digestive system was organized into different functional and histologically differentiated sections, such as the buccopharynx, oesophagus, glandular stomach, and anterior and posterior intestine. This organization resembled that of the juveniles, with the exception of pharyngeal teeth and buccopharyngeal as well as oesophageal goblet cells, which proliferated later during the mixed feeding period. Histological observations revealed that bay snook larvae retained endogenous yolk reserves until 24 dph (8.9 ± 0.4 mm SL), which might be helpful for weaning this species onto a compound diet. The important lipidic accumulation observed in the intestinal mucosa, liver, and pancreas in fish fed a compound trout diet indicated that although fish were able to digest and absorb lipids, the diet formulation did not fit the nutritional requirements of early juveniles of this species. The ontogeny of the digestive system followed the same general pattern as in most cichlid species described to date. However, we detected species-specific differences in the timing of differentiation that were related to their reproductive guild. According to the histological results, some recommendations regarding the intensive culture of this species are also provided.


Although the number of users of home mechanical ventilation (HMV) is increasing, information regarding the users' perceptions of the impact of HMV on their lives is incomplete. We administered an open-ended questionnaire to 98 (48 male, 50 female) HMV users aged (mean±SD) 47.4±19.5 years with COPD (9%), thoracic restrictive disease (43%), and neuromuscular disease (48%). At the time of survey, subjects had received HMV for 59.5±58.3 months. Fifty-three percent were ventilated electively. Ventilator use was continuous (18%), at night only (37%), or at night with occasional daytime use (45%). Twenty-seven (28%) individuals identified themselves as being totally independent while 32 (33%) rated themselves as partially dependent on caregiver assistance for daily activities. Only 37 (38%) considered that they had made an informed choice when first starting HMV whereas 54 (55%) did not. The impact of using a mechanical ventilator was believed to be overwhelmingly positive (87%). Positive comments regarding the impact of the ventilator on lifestyle were grouped in the following categories: life sustaining, facilitating mobility, and improving physical symptoms. Negative comments were grouped in the following categories: limiting mobility, equipment issues, and social implications. HMV users with a tracheostomy volunteered significantly fewer positive statements than those ventilated noninvasively (p


Psychiatry is facing a constant increase of services demands from the population. From one side the improvement of life conditions facilitates the emergence of psychopathology that affects about 50% of the population lifetime 1, from the other psychiatrists often serve as an emergency care in social needs (such as homeless or unemployed) where the psychiatric component is marginal if any. This leads to a demand of care from a very large part of the population with consequences that we will analyze and discuss throughout the editorial. Specifically, in Italy, after more than 30 years of the dramatic change occurred in psychiatry services organization, such aspects impact even more with a generalized unsatisfaction both for patients and staff members, though with some local exceptions 2 3. The 1978 change in the whole body of regulations defining psychiatric activity completely reversed the role of the psychiatrist from a figure mainly devoted to social control (as specified in the 1904 law) to a figure promoting patient autonomy. However both aspects are still present and the psychiatrist faces in the everyday clinical practice this dilemma: benefit of the patient vs. benefit of the social context. Further, the huge demand of care by the population faces a relatively insufficient offer from psychiatric services further impaired by a large heterogeneity in the specific models of care (inpatients vs outpatients, drugs vs. psychosocial treatments and so on) that we will discuss later on 4.


The effects of skew on the standardized item alpha were examined with Monte Carlo techniques. Alphascomputed from normal variables were compared with alphas from lognormal variables, ranks, andskewedversusnormalLikert-typevariables.Theextentanddirectionofskewwerevaried,aswasthesizeof the population interitem correlation (rho), the number of items, and the number of categories forLikert-type variables. Because the average interitem correlation affects alpha and skew affects theaverage interitem correlation, the effect of skew on the average interitem correlation also was examined.Results indicated that skew decreased the average interitem correlation and produced small decreases inalpha that were largest when skew was large, rho was small, items were skewed in opposite directions,and there were fewer items.Keywords: skew, internal consistency, Monte Carlo simulation


We present JASSjr, a minimalistic trec_eval compatible BM25-ranking search engine that can index small TREC data sets such as the Wall Street Journal collection. We do this for several reasons. First, to demonstrate how a term-at-a-time (TAAT) search engine works. Second, to demonstrate that a straightforward and competitive search engine with indexer can be written in under 600 lines of documented code. Third, as a way of providing a simple code-base for teaching Information Retrieval. We present two index-compatible versions (one in C/C++, the other in Java) that compile and run on MacOS, Linux, and Windows. Our code is released under the 2-clause BSD licence, and we provide several suggestions for extensions which might be used as exercises in an Information Retrieval course.


Objective: To identify of the gene responsible for the onset of spinocerebellar ataxia type 16 (SCA16). Methods: We reanalyzed the linkage of the original Japanese pedigree using updated information, including three additional subjects. We then screened all exons located in the critical region. Results: We reassigned the locus of SCA16 to 3p26.2-pter (maximum logarithm-of-odds score = 5.177) and identified only one point mutation (4,256C→T) in the 3′ untranslated region of the contactin 4 gene (CNTN4) on chromosome 3p26.2-26.3, which cosegregated with the disease. This mutation was not detected in 520 control subjects; moreover, we revised the phenotype of SCA16 from pure to complicated SCA. Conclusion: The contactin 4 gene (CNTN4) is associated with cerebellar degeneration in spinocerebellar ataxia type 16. Additional studies are necessary to prove 4,256C→T to be a causative mutation.


We present a method to non-perturbatively determine the long-distance contribution to the $K_{L}$-$K_{S}$ mass difference. The calculation is performed on 2+1 flavor, domain wall fermion, $16^3\times32$ configurations with a 421 MeV pion mass and a kaon mass of 559 MeV . We include only current-current operators and drop all disconnected diagrams in the calculation. The largest contribution comes from quadratically divergent, short distance lattice artifacts. This quadratic divergence is eliminated through the GIM mechanism by introducing a valence charm quark. The remaining short distance effects are then removed by using RI/MOM technique which allows their exact replacement by the physical short distance part.


This paper explores the separate skills and capabilities practiced until now, and the powerful coupling to be achieved, practically and effectively, in implementing a space mission, from inception (pre-phase A) to the end of Operations (phase E). The use of risk assessment techniques in balancing cost risk against performance risk, and the application of the systems engineering team in these trades, is the key to achieving this new implementation paradigm.


This work addresses the task of recommending high quality tags by exploiting not only previously assigned tags, but also terms extracted from other textual features (e.g., title and description) associated with the target object.To estimate the quality of a candidate tag recommendation, we use several metrics related to both tag co-occurrence and information quality. We also propose a heuristic function to combine the metrics to produce a final ranking of the recommended tags. We evaluate our heuristic function in various scenarios, for three popular Web 2.0 applications. Our experimental results indicate that our heuristic function significantly outperforms two state-of-the-art tag recommendation algorithms.


A System of Systems (SoS) is a complex set of IS (Information Systems) created by the aggregation and interconnection of ISs. SoS brings unexpected behavior and functionality during its construction to the benefit of its users and the SoS itself. The integration of SoSs is a matter of time. However, as SoSs can behave as an organization, it may be inappropriate to try to integrate individual IS members separately. On the other hand, manually integrating the SoS as a whole can be unfeasible due to its complexity. If an SoS has ontologies modeling the knowledge, the integration of SoSs can be translated into a problem of a network of ontologies alignment. However, it creates another challenge: computing each possible pair of entities inside each network's ontology can have unfeasible execution time, even using the best matchers available. In this article, we propose to mine the data from the networks using random walks and frequent item sets algorithm and discover relevant nodes elected as candidate entities. Next, the networks are pruned by an algebraic method eliminating identical entities. The relevant nodes are reinserted in the network to avoid losing essential correspondences. After the pre-processing step, data is sent to two matchers to obtain metrics and compare the results with the pairwise brute force approach and previous work. We identified relevant nodes with recall up to 0.75. The results are promising since precision and recall are closer to the force brute, and execution time is shorter, even more, when the size of the networks and the number of ontologies to be compared increases. We validate our approach using ontologies created from the OAEI (Ontology Alignment Evaluation Initiative).


The overlap rate of connectives between different categories of connectives can be viewed directly from the heat map. Therefore, it is necessary to explore a classification method to minimize ambiguity of connectives. A series of methods for automatic classification of connectives in sentence-level are compared in this paper. A combination method is chosen by which we can predict the categories of connectives in a sentence. In the process of automatic classification of connectives, a supervised machine learning algorithm---K-Nearest Neighbor (KNN) was used to classify connectives in order to reduce the ambiguous connectives. However, this method has not gained good effect of automatic classification of connectives. Therefore, authors took another three methods, including Forward Feed Neural Network (FFNN) algorithm, Backward Propagation Neural Network (BPNN) algorithm and a combination method of FFNN&BPNN algorithm. All of these three methods can get better accuracy than the result of KNN algorithm, while the highest accuracy gained by the combination method of FFNN&BPNN among these methods of the experiments. These works can find a maximally disambiguated approach for the classification of connectives that was abstract from Penn Discourse Treebank 3.0 (PDTB3.0).


In the reign of Jiajing of the Ming Dynasty, "Rediscussion of Hetao" ended in Xia Yan and Zeng Xian being killed due to Yan Song's political frame-up and owing to Emperor Shizong changing his mind. Mr Ma Chujian from Hong Kong raises an objection to it, announcing Yan Song's rehabilitation and speaking in defence of Emperor Shizong. The author makes an exhaustive study of the memorial submitted by Yan Song against "Rediscussion of Hetao" after Emperor Shizong had changed his mind. Why Emperor Shizong had changed his mind had much to do with Yan Song's conspiratorial means. So the author thinks that Mr Ma's viewpoint can't hold water.


This article reads Ali Smith's 2014 novel How to Be Both alongside Deborah Levy's Hot Milk (2016) and Sally Rooney's Conversations with Friends (2017). Using Lauren Berlant's conception of neoliberal "crisis subjectivity" and Sara Ahmed's vision of feminist wonderment as an antidote to the neoliberal "promise of happiness," it argues that each novel considers what might be salvaged and what might grow from situations in which young women become attuned to their mutual incarceration in neoliberal time's double bind. It contends that the forced improvisation and feminist reorientation undertaken by the protagonists can be analyzed through the lens of temporality. Finally, it contemplates how the disciplinary-specific modes through which the novels' protagonists consider temporality might be connected to the specific literary projects of their authors.


1. INTRODUCTION. The study of knots and links begins with simple intuitive problems but quickly leads to sophisticated mathematics. This paper will provide the reader with an accessible route that begins with basic knot theory and leads into interesting realms of modern research. The specific topic of the paper is the enhanced linking number, X, a new invariant of links that provides a simple tool to address some of the fundamental problems in the study of linking. The linked rings illustrated on the left in Figure 1 are clearly linked; when a magician pulls such a link apart we know we have been tricked. A mathematical proof that this link is nontrivial depends on showing that its linking number is 1, where the linking number is the basic invariant of link theory, first described by Gauss two hundred years ago. With the link on the right the situation is less clear. If this link is built from rope or beads, then one quickly finds that unlinking the two is impossible. However, formulating a mathematical proof of this is more difficult; for instance, the linking number turns out to be of no help. The enhanced linking number reduces the proof that this link is nontrivial to a simple calculation. This article describes the enhanced linking number and shows how it can be applied to this basic problem of distinguishing links. It will also discuss the role of X in a variety of advanced topics, such as periodicity, symmetry, Brunnian linking, and the modern theory of finite type invariants.


The problem of automatic tracking of ground targets is one of the important issues that UAVs need to face in task applications. The main concern of cooperative tracking is how to track a ground target and maintain the UAV formation simultaneously. In this paper, a new leader-follower formation is constructed to track a ground target. Firstly, a new leader UAV guidance law is proposed to track the ground target in the standoff mode, the stability is proved using a Lyapunov function. Secondly, new guidance laws for standoff tracking of the leader UAV and controlling of the inter-UAV angle of the circle formation are designed for follower UAVs, respectively, stabilities are also proved using two Lyapunov functions. Numerical simulation experiments show that the new leader-follower formation can track the static and moving targets well and its performance is better than the classic LVFG algorithm


This three-volume set combines approximately 12 written articles with 260 essays. Arranged alphabetically by keyword, each of the essays addresses a cultural phenomenon characteristic of the indigenous peoples of North America.


Aiming at the behavior of Argon Bubbles in Slab continuous casting mold with cast speed 1.7m/min,the influence of blowing argon flow rate on bubble size,bubble distribution,the liquid surface level oscillation and behaviors of slag-melt were investigated by using water model and numerical simulation,the 190mm×1900mm slab mold is taken as an object of study.The results show that with increasing gas flow rate in nozzle the size of bubbles in mold increased,the bubble numbers near the narrow face of the mold decreased and most of the bubbles float upward to the surface of the mold in regions around the submerged entry nozzle.The emulsified slag entrapment,metal level bareness and slag entrapment near the nozzle were mainly caused by blowing gas flow rate.


Waveform distortion reduces the phase detection margin in digital magnetic recording systems. Experimental and theoretical investigations into the relation between recording characteristics and waveform distortion of a thin-film head and a sputtered ¿-Fe2O3 disk were performed. Recording current and waveform distortion were measured after the DC-erase, in both directions. It was found that magnetic recording waveform distortion is related to the overwrite characteristics, such that the overwrite value must be maintained at a minimum of 30 dB to keep waveform distortion within 2 ns.


It is investigated the necessity to improve the state financial control as an important factor of realization of financially and budgetary politics of Ukraine and its economic development and identified key shortcomings of its operation. Ways of improving of state financial control in Ukraine are offered on the basis of it and, taking into account the modern state of financially and budgetary relations at state and local levels (decentralization of power and reform of local government)


In this article, we present an adaptive broadband thyristor-controlled impedance matching network (TCIMN) for increasing power utilization from a power amplifier to the loads. Different from the conventional passive impedance matching methods, the proposed one can achieve load impedance matching under a wide frequency range of power amplifiers. First, the operation principle of TCIMN is introduced mathematically. Based on that, the parameter design method is proposed based on the required frequency range. Moreover, the operating range and harmonic analyses are provided to give the TCIMN firing angle operating ranges under different frequencies and alleviate the potential harmonic problem caused by thyristors. To control the proposed TCIMN, the dynamic impedance identification is applied to match the load reactive power adaptively. Finally, the simulation and experimental results of a prototype are given to demonstrate the validity of the proposed TCIMN, analysis, and control method. The results clearly show that the proposed TCIMN can adaptively match the load impedance for the different loads and broadband frequency range. More importantly, the power amplifier power utilization factor is significantly improved without causing harmonic pollutions.


Husband is the senior advisor for root cause analyses in the Office of the Under Secretary of Defense for Acquisition, Technology and Logistics, Peformance Assessments and Root Cause Analyses. He is a retired Air Force officer with a doctorate in chemical engineering from Germany's Karlsruhe Institute of Technology. He is grateful to Gary Bliss, Bob Jennings, Mike Ginter, John Mueller and Ed McDermott for helpful discussions and for providing examples of schedule-driven practices they have observed. Acquisition professionals know that program schedules should be established via "eventdriven" planning. But what is the distinction between a scheduleversus an event-driven program? The author proposes that schedule-driven programs are distinguished not by whether they are behind schedule or have little margin, but by how management sets and controls schedules.


Companies as an economic entity generally have short-term goals, namely to obtain maximum profits and long-term goals, namely to increase the value of the company. Factors that can affect firm value are good corporate governance and environmental disclosure. The purpose of this study is to examine and obtain empirical evidence of the influence of the independent board of commissioners, institutional ownership, managerial ownership on firm value and the role of environmental disclosure in moderating the influence of the independent board of commissioners, institutional ownership, and managerial ownership on firm value. The population of this study is manufacturing companies listed on the Indonesia Stock Exchange which are also listed on PROPER for the 2015-2017 periods. The sampling technique used was purposive sampling technique and obtained sample of 117 companies. The analysis technique in this study uses moderating regression analysis. The results of this study indicate that the independent boards of commissioners, institutional ownership, and managerial ownership have a positive effect on firm value, and environmental disclosure is able to strengthen the influence of the independent board of commissioners, institutional ownership, and managerial ownership on firm value.


A method for measuring the quality of the main parts of optical engine used in the TV projectors and the testing principle are introduced in this paper. Some measuring results are given.


: This study was carried out to select waxy corn inbreds with good general combining ability through a diallel analysis of 10 half diallel crosses among five inbreds developed from Korean maize landraces. Total of 21 agronomic and palatability traits were investigated over two locations in 2016. There was a significant hybrid by location interaction found in plant height, ear height, number of tillers/plant, per ear weight, ear tip filling, ear commercial value and sweetness when four additional check cultivars were included in the analyses. A significant general combining ability by location interaction was found in ear height, number of tillers/plant, per ear weight, ear length and sweetness while ear width, ear commercial value and sweetness were significant for specific combining ability by location interaction. Sweetness was found significant for both interactions. The first and fourth inbred lines had the most number of traits with good estimate of general combining ability. The first inbred is expected to improve days to tasseling, anthesis silking interval, ear width, ear circumference and sweetness while decreasing husk cover in a hybrid combination. The fourth inbred line would improve days to tasseling, days to silking, plant height, ear height, per ear weight and ear length but ears would be a bit tougher than the average. A total of 19 traits had higher variance of general combining ability than that of specific combining ability. Husk cover was 12.1 times higher. Plant height and number of tillers/plant had higher variance of specific combining ability.


In terspersed with spectacular f ire  w orks displays in in terp re ta tion of th e various phases o f American Inde pendence and grow th, th e Ju ly 4 celebration program will begin in the Texas Memorial Stadium a t 7:45, a t which ten or fifteen thousand p er sons are expected to a ttend . This is th e th ird program o f its kind given a t the U niversity, and has been wide ly advertised over cen tral Texas. This y ea r there has been $2,000 spent in th e furnishings for the celebration. Admission is free to students who have blanket tax and an admission charge o f 50 cents will be charged to j J I others. * 1 2 ,0 0 0 A t t e n d a n c e The celebration will begin prom pt ly a t 7 :45. It has been fully adver tised within a radius of f if ty miles by a com m ittee under the chairm an ship o f Mr. Julian Baldwin. Last y e a r m ore than 12,000 people w ere in attendance and even a larger crowd is expected th is year. The program which has been a r  ranged by Dr. M. R. Gutsch is d i vided into five parts. The firs t p a rt is an in troduction , the field being lighted with flood lights displaying a speaker's stand decorated in the U niversity colors. E ight gongs sound th e hour. D irector Gutsch will an  nounce the opening of the celebra tion . This will be followed by invocation by the Reverend W atts, of the U ni v ers ity M ethodist Church, bugle call an d the pyrotechnic display. " The B attle in the Clouds." Then will come the procession con(C ontinuel on page 4) —o -------Student Opinion Asked on Adaption ot Summer School to Semesters


This study is concerned with aerodynamic effects in passive pitching dynamics of insect flapping wings, which would be based on the Fluid-Structure Interaction (FSI). Thus, we evaluated them using three-dimensional numerical analyses for the FSI based on the finite element method. In the numerical analyses, the FSI in insect flapping wing is broken down into its constituent components in order to find the aerodynamic effects in the passive pitching dynamics as follows: (a) The dipteran passive pitching dynamics is based on the interaction between the wing's elastic and aerodynamic forces, while it is enhanced by the wing's inertial effect. (b) The air damping leads the mode of wing's natural vibration from underdamping to overdamping so as to form the characteristic pitching motion, where the damped natural vibration of the wing appears so as to enhance the wing rotation.


Objective To evaluate the value of multi-slice spiral CT angiography in aortic intramural hematoma(AIH). Methods One hundred and eighty-six patients who were suspected of aortic dissection had taken 16-slice spiral CT examination.105 cases of aortic dissection and 23 cases of aortic intramural hematoma(AIH) were diagnosed with different post-processing techniques such as multi-planar reformation(MPR),curved-planar reformation(CPR),maximum intensity projection(MIP).AIHs were classified according to Stanford standard classification. Results Among 23 cases of AIH,6 cases showed type A,17 type B.MSCTA showed the crescent or circular filling defected I aortic cavities.with aortic walls≥5 mm.Five cases presented the formation of local sharp-angled penetrating ulcers but did not show definite intramural piece in aortic cavities.Another 5 cases had pleural effusion and pericardiac effusion.On MPR and CPR,MIP imaging clearly displayed the sites,thickness,extension and complication of the AIH. Conclusions 16 slice spiral CT can provide important information for the diagnosis of aortic intramural hematoma.


With the goal of promoting the development of early career investigators in the field of toxinology, Toxins welcomed applications for the 2016 Toxins Travel Awards for post-doctoral fellows and Ph.D. students. [...]


Aim: To confirm the effect of root canal treatment on radix entomolaris. Case: Radix entomolaris was an additional root that located on the distolingual of mandibular first molars. In this case, the radix entomolaris was detected clinically and radiographically with root canal configuration such as curves. An awareness and understanding of this unusual root and root canal morphology could contribute to the successful outcome of endodontic treatment. Conclusion: Root canal treatment on this case shows the lack of symptoms and normal radiographic presentation for two months follow-up.


Purpose: To evaluate the role of vitrectomy in transscleral fixation of posterior chamber intraocular lens IOL) compared to scleral fixation without vitrectomy. Methods: We reviewed the medical records of 8 eyes which had undergone transscleral fixation with vitrectomy using the three-port-system and 13 eyes which had undergone transscleral fixation only. The postoperative visual acuity, best-corrected visual acuity and changes in astigmatism were compared between the groups. Results: Postoperative uncorrected and best corrected visual acuities were 0.68 and 0.8 in the vitrectomy group and 0.48 and 0.63 in the non-vitrectomy group, respectively. Changes in the amount of astigmatism were significantly less in the vitrectomy group (0.38 diopter) compared to those of the non-vitrectomy group 1.67 diopter). Conclusions: Transscleral fixation of IOL along with three-port-system vitrectomy resulted in good vision with a smaller degree of astigmatism. Adopting three-port-system vitrectomy seems to have caused the good results, because more complete removal of the lens and capsule remnants and adequate maintenance of IOP with accurate needling and IOL positioning was possible using the system.


Thank you for reading mission and menace four centuries of american religious zeal. Maybe you have knowledge that, people have search hundreds times for their chosen novels like this mission and menace four centuries of american religious zeal, but end up in harmful downloads. Rather than enjoying a good book with a cup of tea in the afternoon, instead they cope with some infectious bugs inside their laptop.


This paper focuses the performance and robustness of an algorithm recently proposed in the literature for real-time voltage instability risk indication. Based on local phasor measurements, the real-time identification of the proximity of the equivalent Thevenin impedance seen from an EHV bus and its load impedance is the key to recognize the voltage instability risk at the time it is approaching. The paper highlights the impact of the dynamics of on-load tap changing transformers and generators over-excitation limiters on the Thevenin equivalent identification (and consequently on the timely voltage instability indication). The paper also shows the high reliability of the algorithm with respect to load characteristics and to critical load profiles corresponding to very large perturbations. The paper presents simulation results obtained from a detailed dynamic model of an equivalent single-generator system, as well as from the actual Italian EHV network. Copyright © 2010 John Wiley & Sons, Ltd.


This paper presents a method of lip print recognition using the Dynamic Time Warping algorithm (DTW). The presented method consists of two stages. In the first stage lip print image is subjected to pre-processing which aims to distinct the lip pattern. In the second stage features extraction is performed by generation of the lip pattern image projections: horizontal, vertical and oblique (angle of 45° and 135°). The resulting projections are then compared with each other using the DTW algorithm. Tests were conducted for lip print images acquired from 30 individuals. The results are satisfactory and suggest the possibility of using the method in forensic identification systems.


Using the staining method of aldolase activity in disc electrophoresis gels1), extracts of several higher plants were studied.Spinach, radish and carrot seeds contained a single, aldolase fraction of almost the same mobility. Spinach leaves contained a single aldolase fraction, which migrated faster than that of the seed extract. Radish leaves contained two aldolase fractions, of which the faster moving fraction was more abundant. Radish and carrot roots contained two aldolase fractions. Therefore, it may be concluded that there are two aldolase isozymes in the higher plants, the faster migrating one is specific for leaves, the slower migrating one is specific for seeds. The former may be called leaf aldolase and the latter seed aldolase.


Within the framework of the transformation partnership agreed upon between Germany and Egypt, a project was launced to develop teaching materials on the subject of ancient Egypt to increase the awareness of Egyptian children for the value of their cultural heritage. So far, three booklets on ancient Egyptian writing and scripts, mathematics and the so-called Turin Mining Papyrus have been published.


Acne is a common, inflammatory skin disease of the pilosebaceous unit.1 Patients often have misconceptions about factors exacerbating acne that may influence their treatment seeking behavior. We conducted a cross-sectional study to investigate the perceptions of patients with acne about triggering factors, and how they may differ among adults and adolescents.

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The grafting polymerization of methyl methacrylate (MMA) and cellulose from henequen (Agave fourcroydes) is investigated as a function of the initiator concentration (cerium-and-ammonium nitrate) and the monomer/cellulose ratio. The formation of cellulose-g-PMMA is confirmed by IR spectroscopy, DSC, and TGA. Both the initiator concentration and the MMA/cellulose ratio have a strong influence over the grafting parameters and over the molecular weight of the grafted PMMA. A higher initiator concentration and a lower monomer/cellulose ratio result in a lower molecular weight of the grafted polymer. Increasing the amount and the molecular weight of the grafted PMMA increases the compatibility of the fibers with SAN and PVC, as demonstrated by a mechanical test and scanning electron microscopy. SAN and PVC composites made with grafted cellulose exhibit higher flexural and tensile moduli, respectively, than those produced with the ungrafted fibers. Both moduli increase as the amount of reinforcement increases. © 1997 John Wiley & Sons, Inc. J Appl Polym Sci 66: 339–346, 1997


This study was carried out in the General Commission for Scientific Agricultural Research (GCSAR), Syria, at Der EzZour Agricultural Research Center, from 2008-2010, to examine the effect of salt conditions on some growth attributes and chlorophyll fluorescence in 10 Sugar Beet ( Beta vulgaris L.) genotypes under salinity stress. Sugar beet plants were irrigated with saline water, having electrical conductivity ranged from 8.6-10 dS.m -1 during first year and 8.4-10.4 dS.m -1 during second year. A randomized completely block design with three replicates was used. The results showed that all studied growth attributes, leaf area, leaf number, relative growth rate, and net assimilation rate were decreased in salinity stress conditions compared to the controlled state. The findings indicated that salinity caused a decrement of light utilizing through increased values of fluorescence origin (fo), decreased values of fluorescence maximum (fm), and maximum yield of quantum in photosystem-II (fv/fm). Genotypes differed significantly in all studied attributes except in leaf number. Under salt conditions, Brigitta (monogerm) achieved an increase in net assimilation rate, while Kawimera (multigerm) achieved the lowest decrement in quantum yield in photosystem-II. Further studies are necessary to correlate the yield with yield components under similar conditions to determine the most tolerant genotype. International Journal of Environment Vol.3(1) 2014: 1-9 DOI: http://dx.doi.org/10.3126/ije.v3i1.9937


Compound of formula I; ** ** Formula wherein R1 is a group A or B: ** ** Formula wherein X1 is C1 to 10; X2 is halogen; X3 is halogen or haloalkyl; X4 is C1 to 10; and (1) when R1 is a group A is a group R4 of formula II or R4 and R5 together with the nitrogen to which they are attached form a group of formula III; ** ** Formula R5 is hydrogen or together with R4 and the nitrogen to which they are attached form a group of formula III; X5 is O or -CH2-; X6 is O or -CH2-; R6 is halophenyl, optionally substituted by C1 to 6; 5 R7 is alkyl C1 to 6; R8 is hydrogen or pyridin-3-yl; R9 is hydrogen or methyl; R10 is -COOH or-CHR36COOH; R12 is hydrogen, C1 to 6, alkoxy C1 to 6, hydroxy C1 to 6, -CO2R11 or phenyl optionally substituted with fluoro; R11 is C1 to 6; R13 is hydrogen, C1 to 6 or chlorine; R14 is hydrogen, C1 to 6, methoxy, hydroxy C1 to 6, ethoxycarbonyl, pyridyl, benzo [1,3] dioxol-5-yl or phenyl, optionally substituted by fluorine, C1 to 6; R15 is hydrogen or methyl; R16, R17, R18, R19, R20, which may be identical or different, are each hydrogen or C1 to 6; R21 is C1 to 6; R22 is C1 to 6; R36 and R37, which may be identical or different, are each hydrogen or C1 to 6; (2) when R1 is a group B: R4 is a group of formula IV or R4 and R5 together with the nitrogen to which they are attached form a group of formula V; **Formula**


. Smeets, L. and F. Garretsen. 1986. Growth analyses of tomato genotypes grown under low night temperatures and low light intensity. Euphytica 35: 701–715. Tindall, J. A., H. A. Mills and D. E. Radcliffe. 1990. The effect of root zone temperature on nutrient uptake of tomato. J. Plant


Background: Cancer patients are at higher risk of developing severe COVID-19 and worse virus-related outcomes. In addition, low- and middle-income countries may be even more impacted by COVID-19, and not offer appropriate end-of-life support to many patients. The aim of this study was to evaluate the palliative care offered to cancer patients with COVID-19 in a major referral hospital in South America. Methods: Descriptive and retrospective study in Hospital das Clínicas, Faculty of Medicine of the University of São Paulo, Brazil. This hospital is considered one of the major referral and public hospitals in South America. Medical records of adult cancer patients admitted for COVID-19 were reviewed. Patients were screened for the need for palliative care through Supportive and Palliative Care Indicators Tool (SPICT). Data was analyzed using Stata 14. Results: The sample was composed of 317 Latino patients, of which 155 (48.9%) were male and 162 (51.1%) were female. Median [IQR] age was 68 [56-81] years old. In addition, 119 (37.5%) were admitted to the wards, 110 (34.7%) to the emergency room, and 88 (27.8%) to the intensive care unit. Patients admitted to the wards were more likely to receive palliative care (46.7% vs. 32.9%;p=0.016). A total of 107 (33.7%) patients had access to palliative care. Regarding SPICT criteria, 260 (82.0%) were at risk of deteriorating and dying. Of the patients who met SPICT criteria, 98 (37.7%) had access to palliative care during hospitalization. Regarding outcomes;155 patients (48.9%) died, 128 (40.4%) were discharged, and 34 (10.7%) were transferred to another unit. Of the patients who died, 72 (46.5%) did not have access to palliative care. Conclusions: In our study, there was a high mortality rate in Latino cancer patients with COVID-19, although a considerable percentage of them did not have access to palliative care before dying. It is important to give further attention to the end-of-life support offered to cancer patients with COVID-19, especially in underserved communities and among racial/ethnic minorities.


The massive heterogeneous web information resources flood on the internet, and the web pages classified have no relation with each other. In this paper, the topic knowledge repository is built to find the semantic relation between web pages, and the similar relation and the associated relation are defined to describe the semantic relation, which helps to provide knowledge service for user and other services. Web pages are represented by Vector Space Model and classified by the sample web pages which are chosen previously, through the topic knowledge repository, the semantic relation between web pages can be found. In the clothing industry, an improved classification algorithm is proved to be much better via the experiment, and a method proposed to find the semantic relation between web pages is proved feasible


Stumpage contract prices in western Oregon and Washington nearly doubled between 1 977 and 1 980 on forest service lands, When product demand subsequently collapsed, the implicit stumpage market value fell below contract stumpage costs, Timber harvesting rights on most public lands (and some private) are awarded by the landowner through a competitive bidding process, Mills bid for the stumpage, and the bid becomes the fee for removing standing timber. Contracts in the Northwest typically extend for three years (although a few longer terms exists), If it is successful in bidding for the stumpage, the mill obligates itself to remove a specific quantity of timber within the I ife of the contract and to pay the bid price at the time of harvest.


Abstract Molecular dynamics simulations for models of poly(Vinyl Alcohol) hydrogels and pure water have been carried out over a wide temperature range including the glass transition temperature to examine structure and dynamics of supercooled water in hydrogels. The temperature dependences of thermodynamic properties and rotational relaxation times at atmospheric pressure are investigated. Those properties depend seriously on mobility of polymer chains and network structures of hydrogen bonds. It is found that polymer chains affect significantly the dynamic properties and the fragile-strong character of water. Structure and dynamics of water in PVA hydrogels are characterized by two dynamical modes, the motion of main chains and that of side chains, whose time scales are different from motion of water.


Social computing examines the interactions between users and media across diverse cultures. Currently the Internet is the most prominent example and has fostered the development of new social interaction paradigms. This paper surveys the research literature in social computing and connected media and then introduces an emerging area, social webconsciousness, which describes the experiential nature of social interactions over the Internet.


In 2008, Universite Laval launched the first and only graduate programs in biophotonics in Canada. This initiative is dedicated to the training of a new generation of highly qualified researchers at the interface of life sciences and optics. It also stemmed from the strong expertise of the University in optics/photonics, its major investments in state-of-the art biophotonics infrastructure and technologies, and its desire to promote multidisciplinary training of graduate students. The programs are hosted by the Faculty of Science and Engineering in collaboration with the Faculty of Medicine, regrouping professors from 3 Faculties and 10 departments at Universite Laval. The biophotonics graduate programs offer students from a wide variety of scientific backgrounds the opportunity to train in highly skilled research teams on projects that bridge the gap between traditional research fields. They benefit from transdisciplinary training opportunities in the fields of physics, chemistry, biology, biochemistry, neurosciences, medicine, engineering and ethics.


This paper challenges two tacit assumptions in the field of intercultural communication research. Firstly, misunderstandings can frequently be found in intercultural communication, although one cannot claim that intercultural communication is characterised by misunderstandings alone. The main analytical task should be to linguistically reconstruct intercultural understanding. Secondly, intercultural communication is not solely constituted by the fact that interactors from different cultural groups interact. Each analysis should detect to what extent instances of discourse are institutionally and/or interculturally determined. This paper discusses how some analyses of intercultural communication go beyond the analysis of misunderstanding. Consequently, a shift can be observed in the research focus towards the question as to what extent different linguistic means contribute to intercultural understanding. The paper begins with an introduction to the historical background to the interest in intercultural communication and presents the main approaches to the study of culture in discourse. Subsequently, two analyses of beyond misunderstanding are discussed: Clyne's (1994) revision of the Gricean conversational implicature and its maxims, and ten Thije's (2002b) three-step strategy for intercultural understanding including generalising, perspectivising and contrasting cultural standards in discourse. The data consists of narratives by East and West Germans about the famous East German car the Trabant. The system change from socialist to market economy has influenced everyday life deeply in Germany and the Trabi stories document how new solutions were found for everyday needs, and old and new cultural identities are constructed.


Objective To explore the clinical characteristics and pathogenesis of spontaneous suprachoroidal hemorrhage.Methods A case was reported and the related literatures were reviewed.Result The pathogenesis of primary systemic amyloidosis was not clear.Posterior sclerotomy at a suitable time,which could decrease the complications of spontaneous suprachoroidal hemorrhage,reduced the rate of eye atrophy and maintain visual function.Conclusion Partial suprachoroidal hemorrhage may be improved the early diagnosis and the early therapy.Extensive suprachoroidal hemorrhage has a bad prognosis.


The rapid growth of the larger corporations in the US from the late nineteenth century onwards made the question of the appropriate structure for these new corporate giants of increasing importance to management writers. Particularly difficult was the relationship between line management and functional management as management hierarchies lengthened and specialisms grew in number and scope. Developing ideas from F.W. Taylor and Harrington Emerson by US and UK writers brought confusion as much as it brought progress. Attempts from the late 1920s to evolve organisational proposals by establishing principles of organisation brought modest advances but no conceptual breakthroughs. By the Second World War no management writers appear to have proposed or identified anything resembling the multidivisional form.


One of the main factors preventing the increase of the input power of optical fibers is the saturation of the input power by stimulated Brillouin scattering (SBS). In this paper, theoretical and experimental investigations are performed of three methods for suppressing SBS. the first method is to enlarge the optical fiber Brillouin gain bandwidth by applying a periodic strain distribution in the longitudinal direction of an optical fiber using the structure of the optical fiber cables. the second method is to shift the frequency of the Brillouin gain spectrum by connecting fibers with different core dopant concentrations. the third method is the combination of the two methods described above.

In the cable described in this paper, a sinusoidal strain distribution was induced in the fibers with a maximum strain amplitude of 0.4 percent and a pitch of 600 mm by using a double-stranded structure. By doing so, the Brillouin gain bandwidth could be enlarged up to 400 MHz. Also, a frequency difference of 580 MHz is induced by connecting fibers with a dopant difference of a maximum of 4.4 percent between each fiber. It is shown that the SBS can be suppressed upto a CW optical input power of +17.4 dBm by widening the bandwidth and connecting optical fibers with shifted bandwidths. There fore, it is concluded that the proposed method is effective and practical for SBS suppression.


A synthetic image is a critical issue for computer vision. Traffic sign images synthesized from standard models are commonly used to build computer recognition algorithms for acquiring more knowledge on various and low-cost research issues. Convolutional Neural Network (CNN) achieves excellent detection and recognition of traffic signs with sufficient annotated training data. The consistency of the entire vision system is dependent on neural networks. However, locating traffic sign datasets from most countries in the world is complicated. This work uses various generative adversarial networks (GAN) models to construct intricate images, such as Least Squares Generative Adversarial Networks (LSGAN), Deep Convolutional Generative Adversarial Networks (DCGAN), and Wasserstein Generative Adversarial Networks (WGAN). This paper also discusses, in particular, the quality of the images produced by various GANs with different parameters. For processing, we use a picture with a specific number and scale. The Structural Similarity Index (SSIM) and Mean Squared Error (MSE) will be used to measure image consistency. Between the generated image and the corresponding real image, the SSIM values will be compared. As a result, the images display a strong similarity to the real image when using more training images. LSGAN outperformed other GAN models in the experiment with maximum SSIM values achieved using 200 images as inputs, 2000 epochs, and size 32 × 32.


2010 is the 50th anniversary of the industrialization of ESR Technology.The article discusses the classification of electroslag metallurgy technology,history,the"stage",the second generation of large electroslag metallurgy technology features and the second generation of ESR ingots and large ESR ingot pouring liquid metal and other major equipment manufacturing and nuclear power industry relations.Author pointed out: China's large-scale development of ESR ingots,the ESR has been in the world power status.As China's major equipment manufacturing technology is developing rapidly,especially the rapid development of China's nuclear power industry,large ingots electroslag metallurgy technology will continue to improve with the development,which in turn will promote the technical aspects of nuclear power in China quickly catch up with international advanced level.


[Abstract]: A resonant cavity method was employed to measure the e″ of low loss thermoplastic composites e.g. 33% by weight glass fibre reinforced low density polyethylene [LDPE/GF (33%)]. The values of e″ obtained by suspending the sample upright in the middle of the cavity were acceptable but the values of e′ procured were far away from those obtained by other measuring methods, particularly at higher frequencies using WR159 and WR90. This paper describes the same method with the sample placing on the floor of the cavity. The sample thickness was also reduced to two-third of the original value. The values of Q factors procured by different methods were also compared and discussed.


There is a massive amount of high dimensional data that is pervasive in the healthcare domain. Interpreting these data continues as a challenging problem and it is an active research area due to their nature of high dimensional and low sample size. These problems produce a significant challenge to the existing classification methods in achieving high accuracy. Therefore, a compelling feature selection method is important in this case to improve the correctly classify different diseases and consequently lead to help medical practitioners. The methodology for this paper is adapted from KDD method. In this work, a wrapper-based feature selection using the Genetic Algorithm (GA) is proposed and the classifier is based on Support Vector Machine (SVM). The proposed algorithms was tested on five medical datasets naming the Breast Cancer, Parkinson's, Heart Disease, Statlog (Heart), and Hepatitis. The results obtained from this work, which apply GA as feature selection yielded competitive results on most of the datasets. The accuracies of the said datasets are as follows: Breast Cancer - 72.71%, Parkinson's – 88.36%, Heart Disease – 86.73%, Statlog (Heart) – 85.48 %, and Hepatitis – 76.95%. This prediction method with GA as feature selection will help medical practitioners to make better diagnose with patient's disease.


The Mediterranean as a region remains a source of political and social instability. Most security issues in the re gion are currently driven by soft security socio -economic conditions rather than hard security politico -military factors. The EU's Barcelona Process and NATO's Mediterranean Dialogue complement each other through their specific strength. The success of the Dialogue depends on the active participation and strong support by both EU/NATO and Dialogue countries alike, working together to build the trust and transparency required for a true partnership.


In recent years there has been an increasing appreciation that microbial biofilms are ubiquitous, which has resulted in a number of studies on infectious diseases from a biofilm perspective. Biofilms are defined as structured microbial communities that are attached to a surface and encased in a matrix of exopolymeric material. A wide range of biomaterials used in clinical practice have been shown to support colonization and biofilm formation by Candida spp., and the increase in Candida infections in the last decades has almost paralleled the increase and widespread use of a broad range of medical implant devices, mainly in populations with impaired host defenses. Formation of Candida biofilms has important clinical repercussions because of their increased resistance to antifungal therapy and the ability of cells within biofilms


Abstract One of the most important theological questions in the first Origenist controversy was that of the resurrection of the dead. Jerome accused both Origen and contemporary "Origenists" of speaking only of the resurrection of the body, and not of the flesh, and he claimed that an idea of resurrection without the flesh could not guarantee the identity between the body living on earth and the resurrected body. I argue that although Jerome attempted to maximize the difference between himself and Origen by speaking of flesh instead of body, and by emphasizing the sameness of the body, it is clear that he, too, thought that the resurrection would imply a profound change. At closer scrutiny, Jerome's way of understanding this change, namely as the nature remaining the same while the glory increases, shows striking similarities to Origen's explanation of change. I argue that Jerome was dependent on Origen's ideas about the resurrection, even in his polemics against him. Jerome's heresiological strategies, I argue, have had consequences for modern historical reconstructions of his eschatological thought, which is often presented in opposition to Origen's more spiritual understanding. Awareness of the rhetorical strategies used by Jerome in the context of controversy is crucial, I claim, in assessing a continuing reception of Origen in his theology.


This research sought to find if a significant relationship existed between a factor of personality, authoritarianism, as measured on the Rokeach Dogmatism Scale, and perceived effectiveness of teaching as measured by ratings on the Purdue Rating Scale for Instruction.


We present a comparison between the electronic structures of inverse opal (IO) and nanoparticulate (NP)-TiO2 electrodes. The electronic structure details were obtained from optical absorption, fluorescence, and valence band studies in order to clarify the nature of the higher photovoltaic performance observed in sensitized solar cells using IO-TiO2 electrodes. We used photoacoustic (PA) and photoluminescence (PL) spectroscopy to characterize the optical absorption and fluorescence properties, respectively. Photoelectron yield (PY) spectroscopy was applied to characterize the position of the valence band maximum (VBM) of the IO- and NP-TiO2 electrodes. The PA spectrum for IO-TiO2 is different to that for NP-TiO2, indicating differences in the exciton–phonon interactions and the density of states in the conduction band. PL measurements showed that the curvature of the valence band structure of IO-TiO2 is different to that of NP-TiO2. Also, PL measurements showed that the oxygen vacancy in IO-TiO2 is different to that in NP-TiO2. Moreover, PY measurements showed VBM in IO-TiO2 to be at a higher position than that in NP-TiO2, suggesting a correlation with the increased open circuit voltage (Voc) in sensitized solar cells.


to the editor: We thank Drs. Young, Keller, Crandall, and Fadel ([2][1]) for their interest in our work ([1][2]), and their opinions regarding the impracticality of comparing skin sympathetic nerve activity (SSNA) between subjects in different groups. Since single SSNA bursts can include multiple


cDNA clones encoding porcine kappa-casein were isolated and sequenced. The porcine kappa-casein cDNA is 851 bp in length and encodes a preprotein of 188 amino acids.


The proliferation of cybercrime necessitates all internet-connected states to be involved in cybercrime regulation. Although it has been stated that the internet per se and cyberspace in general are by its very nature ungovernable, many states have taken territorial control of the internet although the effectiveness of such control in cross-border crime commission may be questioned. The internet may very well become ungovernable if a nation-state takes a unilateral decision on which conduct constitutes permissible online conduct or endeavours to superimpose laws on other nation-states. It is therefore suggested that under the auspices of the United Nations and within an international law context the following issues should be addressed: conceptualizing the term "cybercrime" in establishing for example whether it includes a cyber-attack, determining which online conduct is permissible to ensure peace and security and initiating negotiations towards a Cybercrime Treaty.


The PHENIX experiment reports systematic measurements at the Relativistic Heavy Ion Collider of $\phi$-meson production in asymmetric Cu$+$Au collisions at $\sqrt{s_{_{NN}}}$=200 GeV and in U$+$U collisions at $\sqrt{s_{_{NN}}}$=193 GeV. Measurements were performed via the $\phi\rightarrow K^{+}K^{-}$ decay channel at midrapidity $|\eta|<0.35$. Features of $\phi$-meson production measured in Cu$+$Cu, Cu$+$Au, Au$+$Au, and U$+$U collisions were found to not depend on the collision geometry, which was expected because the yields are averaged over the azimuthal angle and follow the expected scaling with nuclear-overlap size. The elliptic flow of the $\phi$ meson in Cu$+$Au, Au$+$Au, and U$+$U collisions scales with second-order-participant eccentricity and the length scale of the nuclear-overlap region (estimated with the number of participating nucleons). At moderate $p_T$, $\phi$-meson production measured in Cu$+$Au and U$+$U collisions is consistent with coalescence-model predictions, whereas at high $p_T$ the production is in agreement with expectations for in-medium energy loss of parent partons prior to their fragmentation. The elliptic flow for $\phi$ mesons measured in Cu$+$Au and U$+$U collisions is well described by a (2+1)D viscous-hydrodynamic model with specific-shear viscosity $\eta/s=1/4\pi$.


Analysis of data is the foundation of multiple scientific disciplines, manifesting in complex and diverse scientific data analysis workflows often involving exploratory analyses. Such analyses represent a particular case for traditional data engineering workflows, as results may be hard to interpret and judge whether they are correct or not, and where experimentation is a central theme. Oftentimes, there are certain aspects of a result which are suspicious and which should be further investigated to increase the trustworthiness of the workflow's outcome. To this end, we advocate a semi-automated approach to reducing a workflow's input data while preserving a specified outcome of interest, facilitating irregularity localization by narrowing down the search space for spotting corrupted input data or wrong assumptions made about it. We outline our vision on building engineering support for outcome-preserving input reduction within data analysis workflows, and report on preliminary results obtained from applying an early research prototype on a computational notebook taken from an online community of data scientists and machine learning practitioners.


Background:  The physical‐chemical properties of perfluorochemical (PFC) liquids have been shown to influence physiological and cellular responses during partial liquid ventilation (PLV). The aim of this study is to compare the relationship between patho‐physiological endpoints and the physical properties of three PFC liquids used in treating acute lung injury.


Larval food plants (LFPs) of Sri Lankan butterflies have been well documented recently with the aid of studies done by numerous researchers. In this paper, we present further records, 118 LFPs used by 83 butterflies and 145 plant-butterfly combinations. LFPs of Lethe dynsate and Potanthus pseudomaesa pseudomaesa are reported for the first time in Sri Lanka. Important observations, possible LFPs and LFP preferences of rare and threatened butterfly species, are discussed. This information on plant-butterfly interactions will play an important role in conservation management of both plant and butterfly species.


We have recently completed a survey of the peculiar velocities of 1355 southern spiral galaxies. The Tully - Fisher relation was used to estimate the distances to the spirals. The photometry was done in the I-band using CCDs on the lm telescope and the Anglo-Australian Telescope at Siding Spring Observatory. The rotational velocities were measured from 1042 H-alpha rotation curves obtained with the 2.3m telescope at SSO and 609 H 1 profiles obtained with the Parkes radio telescope. The most important result of these measurements is that we do not detect backside infall into the Great Attractor, rather we find bulk motions of 600km/s on scales of 80h Mpc in the direction 1 = 310 , b = 15 . Willick recently found bulk motions of about this magnitude and direction from his survey of the peculiar velocities of spirals in the direction of Perseus -Pisces. When combined with our result this implies bulk motions of about 500km/s over scales of 150h Mpc. The far-reaching implications of these raises


Chronic administration of the nitric oxide synthase inhibitor L‐NAME causes arterial hypertension and renal injury. The purpose of this study was to evaluate in hypertensive animals induced by L‐NAME the renal hemodynamic and renal function using isolated perfused kidney model. The rats (n=5, each group) were divided in: 1)Normotensive (Nt), without treatment and 2)Hypertensive group: L‐NAME administration in the drinking water (600 mg/L) during 7 days (H7). L‐NAME treatment induces an increase in arterial blood pressure (143 +/− 2.2 vs. 105+/− 1.8 mmHg, H7 vs. Nt). Isolated kidneys were perfused with Krebs‐Henseleit solution containing 6g of previously dialysed bovine serum albumin for 60 min. The treatment increased the perfusion pressure (Nt=103.4 +/−1.2; H7=143+/−7.66 mmHg), and renal vascular resistance (Nt=4.5+/−0.51; H7=14.01+/−0.7 mmHg). These alterations were accompanied by a reduction of the urinary flow (Nt=0.16+/−0.01; H7=0.09+/−0.02 mL g(‐1) min(‐1)) and glomerular filtration rate (Nt=0.84+/−0.075; H7=0.19+/−0.032 mL g(‐1) min(‐1)). These finding showed that NO generated within the kidney contributes to the regulation of renal vascular tone in rats. In conclusion, our data suggests that NO inhibition induces dramatic changes in renal function demonstrated in the ex‐vivo kidney perfusion.


Since the 1980s, China and Mexico adopted market-oriented public policies, which impacted all spheres of their respective societies. This study pays special attention to the areas of income, literacy, and urbanization; identifies relevant policies effects on their educational systems; and proposes a model of education index for analyzing their transformations. It found regional inequalities between west and east China and southern and north-central Mexico a crucial factor that affects the Education Index. In conclusion, we provide a theoretical and practical understanding of the education inequalities occurred in both countries.


In the current context we are witnessing the growing incidence of threats from biomedical advances against major values "‹"‹of humanity. These threats are linked to the prevalence of scientific and technological factors but also structural conditions of extreme vulnerability that impact on developing countries, forcing us to rethink concepts and models approach on issues that enable the debate over the controversial aspects Bioethics and conscientious objection. Biomedical and medical research and healthcare practice, installed as long debates on the legality and necessity.
However, these debates are strongly incised by the structural conditions of the societies in which they occur. In contexts marked by vulnerability, concepts populations face barriers to their uptake, and the old and the new coexist without change can be articulated on continuity.
Consequently, in this paper it will seek to address the influence of contextual factors that determine discussions on topics of bioethics and conscientious objection in the context of Latin American societies, characterized by deep structural asymmetries which become vulnerable conditions. We will also consider the role of education in the recognition and dissemination of topics of bioethics and conscientious objection in the context of these structural conditions.


[President Washington] possessed a deep-seated understanding of the importance of good administration both as a means of consolidating popular support for the general government, and as an essential source of strength of the government itself. He understood good administration to be characterized by integrity, system, energy, reliance on facts, relative freedom from detail, and due responsibility to Congress. (The Federalists, 1948, p. 114).


This article aims to analyze reference-memories of three teachers beginning their careers in higher education, through (auto)biographical research. For that, an interview was used with questions about life history, school education, academic path and professional development. The aspects highlighted by them in the study demonstrated considerable elements in the choice of the profession and the constitution of teaching learning. In view of the reference-memories, it was evident that the marks and images of teaching come from a repertoire of these subjects' own life history. Such reminiscences are loaded with positive and happy feelings configured by the family influence in the referred choice, by trajectories with the old masters, in addition to the games and the processes of insertion/initiation to teaching at the university. Learning in this area did not happen in a neutralized way, but rather woven by the training paths experienced by teachers in their life stories and by professional journeys in maintaining or overcoming beliefs and values about the teaching profession. Furthermore, the subjectivities that permeate the construction of teachers' identity were seen, that is, how 1 Translated by Ívina Natalino do Carmo: E-mail address: email@example.com. 2 This study had the support of Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) – Financing Code 001. DOI: http://dx.doi.org/10.1590/0104-4060.75550 * Universidade do Tocantins. Arraias, Tocantins, Brazil. E-mail address: sebastiaosilva@uft. edu.br https://orcid.org/0000-0002-5572-014X ** Universidade Federal de Uberlândia. Uberlândia, Minas Gerais, Brazil. E-mail address: firstname.lastname@example.com https://orcid.org/0000-0002-8956-9564 DOSSIER The biographical dimension as formation process, self comprehension and world understanding Educar em Revista, Curitiba, v. 37, e75550, 2021 1 they were constituted in the profession and in various historical contexts of formation.


In the wake of corporate scandals involving companies such as Enron, Arthur Andersen, WorldCom, and Tyco, the Association to Advance Collegiate Schools of Business (AACSB) International adopted modifications to its accreditation standards for business schools. Much of the debate over adopting ethical standards focused on the merits of covering ethics in a specialized course versus integrating ethical analysis throughout the curriculum. This debate is timeworn and unresolvable. Curriculum-based efforts should be continued, of course, but students, business schools, prospective employers, and society must come to understand that ethics in business education is about conduct as well as coursework. Moreover, the strategies utilized by students in pursuit of a degree are a persuasive predictor of the actions they will take after graduation: individuals who cheat to get good grades are more likely to follow unethical paths in their careers. This article is based on the premise that there is a relationship between academic integrity and business ethics. The AACSB, business schools, and employers should acknowledge this link and explicitly communicate, through their actions, that academic dishonesty is critically relevant.


The nucleus of the tractus solitarius (NTS) is the site of integration of several autonomic functions. Lesions occurring in this part of the brainstem are lethal, and for this reason, one century ago, this structure was named "noeud vital."' It is known that the control of respiratory* and cardiovascular3 functions requires the integrity of the NTS. This nucleus constitutes the most important part of the respiratory network which is responsible for the central respiratory rhythmogenesis.' The NTS receives direct projections from vagal (Xth) and glossopharyngeal nerves (IXth),' and therefore receives the afferent inputs from arterial baroreceptors, chemoreceptors, and lung stretch receptors: Different neuropeptides have been found in this part of the central nervous system. Some of them, such as the opioid peptides, are located in somata as well as in terminal^.^ Other neuropeptides such as substance P are more particularly located in terminals' and may be vehiculated by vagal afferents.' Cholecystokinin octapeptide (CCK-8) is present in the NTS, located mostly in terminals.'o Since it has been found in the vagus nerve'' and since CCK concentration is reduced in the NTS after destruction of tractus solitarius afferents,'* terminals containing CCK may originate in IXth and Xth cranial nerve ganglia. However, other possibilites cannot be excluded since somata immunoreactive to CCK-like substances have been located in the pontine parabrachial nucleus, which projects partly to the NTS, and in the hypothalamus, which also projects to the NTS." We have previously demonstrated the involvement of neuropeptides, especially that of opioid pep tide^'^ and substance P,I5 in autonomic functions regulated by the NTS. The aim of this study was to investigate the possible role of CCK in the control of cardiovascular and respiratory functions by the NTS.


The paper considers vector ARMA processes with nonstationary innovations. It is suggested that this class of models provide a very efficient framework for nonstationary problems. A generalization of the Yule-Walker equations relating the underlying process is obtained. Identification procedures are discussed. The associated prediction problem is solved using the Hilbert space approach.


Purpose – The purpose of this paper is to derive a new method for developing sizing systems for the mass customization of garments.Design/methodology/approach – A range of recently published works has been studied. A new method is derived by following a basic statistical analysis on anthropometric data which are supported by an iterative mass customization model and introduced "satisfaction performance" indices. The derived method is applied successfully to an anthropometric data consisting of 12,810 Greek men.Findings – With the proposed method, it is possible to control the degree of mass customization and the corresponding number of garment sizes. Under this way, a balance between the number of sizes (in other words: production cost) and the percentage satisfaction of consumers can be achieved. The proposed method consists of six subsequent tasks which are applied to the target population data for the development of mass customization models for male shirts, coats and trousers.Research limitations/impl...