: In present scenario, imaging in act an important role throughout the integrated medical process from indicative and find out about diseases through studies. Considering most of the imaging techniques have gone directly digital, with unceasingly increasing perseverance, these medical image processing has to confront many upcoming challenges from broad data measures. In our paper we describe the process of analysing cancer cell and how image processing is helpful and immensely important in medical science. The paper analyse and discover bacteria under blood cells through its rate of growth of bacteria in blood with the help of object recognition technique of image processing by getting the image through microscope. This work presents an precise way of static image processing technique of object recognition for detection and prognosis of cancer cell. This method used for diagnosis of abnormal growth of cells in any body part using blood cell image. This procedure include artificial expert system techniques, such as machine learning, artificial neural network, and fuzzy logic with medical imaging techniques. We subsist blood images as input for our expert system to analyse and detect the classification of growth of abnormal cell through static image processing technique. This paper presents another technique of image processing as pattern recognition for analysis and classification of cancer cells using microscopic blood cells images..The proposed method achieved sensitivity of 80%. specificity of 91.04% and accuracy of 96.4%. Bayesian Logistic Regression (BLR) and k-star by using classification accuracy and error rate based on the percentage split method. The result shows that the best algorithm in WEKA is MLP classifier with an accuracy of 83.333% and kappa statistics is 0.625.


Diesel spray experiments at controlled high-temperature and high-pressure conditions offer the potential for an improved understanding of diesel combustion, and for the development of more accurate CFD models that will ultimately be used to improve engine design. Several spray chamber facilities capable of high-temperature, high-pressure conditions typical of engine combustion have been developed, but uncertainties about their operation exist because of the uniqueness of each facility. For the IMEM meeting, we describe results from comparative studies using constant-volume vessels at Sandia National Laboratories and IFP. Targeting the same ambient gas conditions (900 K, 60 bar, 22.8 kg/m{sup 3}, 15% oxygen) and sharing the same injector (common rail, 1500 bar, KS1.5/86 nozzle, 0.090 mm orifice diameter, n-dodecane, 363 K), we describe detailed measurements of the temperature and pressure boundary conditions at each facility, followed by observations of spray penetration, ignition, and combustion using high-speed imaging. Performing experiments at the same high-temperature, high-pressure operating conditions is an objective of the Engine Combustion Network (http://www.ca.sandia.gov/ECN/), which seeks to leverage the research capabilities and advanced diagnostics of all participants in the ECN. We expect that this effort will generate a high-quality dataset to be used for advanced computational model development at engine conditions.


Writer identification is a sub-field in handwriting recognition which its objective is to determine the identity of the writer based on handwriting input. The goal is usually for forensic purposes such as finding the perpetrators of crimes that leave traces of evidence in the form of written messages. In addition, writer identification can also be used to determine the identity of a historical actor if he or she leaves a valuable written artefact. The object of this research is the traditional character of the Lampung region which is so-called Had Lampung by the local community. The traditional character of Lampung consists of 20 main characters and 12 diacritics. Based on selected characters, the writer will be recognized using the Principal Component Analysis (PCA) feature. PCA is one linear feature extraction method of an object in pattern recognition. The PCA algorithm consists of several stages, namely the calculation of the average dataset, the subtraction of the vector dataset with averages, the calculation of covariance, the calculation of eigenvectors and eigenvalues, eigenvector reduction, and the projection of the dataset against reduced eigenvector space. PCA in this paper is used as a feature in image recognition. The dataset utilized in this study is the Lampung Dataset which is a handwritten character recognition (HWCR) dataset. Lampung Dataset consists of 82 Lampung handwritten documents. All Lampung character images in the dataset were extracted from these documents using the connected component extraction algorithm and eventually generated 32,140 images. Furthermore, these images are converted into grayscale images. In this research, as many as 12,500 grayscale images of Lampung handwriting characters were chosen to represent 82 different writers. This data is employed as training and testing data on the proposed method. The highest accuracy of the identification of the writer using this PCA feature is 82.92%, while the lowest accuracy is 28.29%.


A Study to Identify the Factors that Inhibit High School Principals and Teachers from Pursuing Bachelor's and Master's Degrees in Busia District in Kenya by Samuel O. Obaki This study sought to examine the factors that inhibited principals and teachers from pursuing bachelor's and master's degrees in Busia District in Kenya. Up to the mid1990s, teachers of all professional grades studied for National Examinations as private candidates. Those who met university admission requirements were admitted and the Teachers Service Commission granted each of them a study leave with 80% of his or her salary. Some of those who met university admission requirements were admitted to foreign universities, and the Ministry of Education either granted them study leave with or without salary. On passing their examinations or completion of their studies, they were promoted on academic grounds. After the mid-1990s, the Kenyan Ministry of Education changed its policy from promotions on academic grounds to "merit promotions". Merit promotion considered a teacher's teaching effectiveness, co-curricular activities, community involvement, and the principals' recommendations. Merit promotion was applied to those in job group M and above after serving in one job group for at least three years. Promotions from job group J, which was a starting point of a graduate teacher, to job group K, and from K to L, were automatic, provided that a teacher had been in one job group for three consecutive years of service. Although copies of academic qualifications were required when applying for promotion, the Kenyan Ministry of Education did not promote teachers from one job group to another on the basis of their attainment of higher academic qualifications. Consequently, teachers did not pursue further studies because they were not going to be promoted. The purpose of this study was to determine the factors that inhibited teachers from pursuing bachelor's and master's degrees. Stratified purposeful sampling was used to select the participating schools. Thirteen out of 27 high schools were chosen. All teachers in the chosen schools were invited to participate in the study. One hundred thirty-one out of 214 teachers, (61.2% of the total), including principals, completed questionnaires. Nine of the 13 principals invited (69.2%) completed the questionnaire. Conclusions were drawn from the participants' responses. There were overwhelming data expressing the views that widespread teachers' poverty and the policies of the Kenyan Ministry of Education were the major inhibitors of teachers' efforts to pursue bachelor's and master's degrees.


This paper discusses the trade policies and practices of Singapore based on the latest WTO trade policy review. Though Singapore's trade policies have been effective and contributing to its remarkable economic performance, it also faces problems and new challenges in the modern globalisation era. Reviewing Singapore's policies also provides guidance for other small open economies.


Most recommender systems (RSs) predict the preferences of individual users; however, in certain scenarios, recommendations need to be made for a group of users. Tourism is a popular domain for group recommendations because people often travel in groups and look for point of interest (POI) sequences for their visits during a trip. In this study, we present different strategies that can be used to recommend POI sequences for groups. In addition, we introduce novel approaches, including a strategy called Split Group, which allows groups to split into smaller groups during a trip. We compared all strategies in a user study with 40 real groups. Our results proved that there was a significant difference in the quality of recommendations generated by using the different strategies. Most groups were willing to split temporarily during a trip, even when they were traveling with persons close to them. In this case, Split Group generated the best recommendations for different evaluation criteria. We use these findings to propose improvements for group recommendation strategies in the tourism domain.


Malthusian anxieties in speculative fiction' (p. 270). Overpopulation and its effects on ecology had already become a staple of science fiction stories before the Population Council was set up but the council's 'propagandising familiarised the idea' (p. 271); later US pressure groups such as Zero Population Growth also bolstered interest in science fiction, leading to a production surge in the genre which Stableford situates around 1971. The book ends with some engaging discussion of 'the notion of a "carbon footprint": the dark dystopian stain left on the earth's surface by the passage through life of every human being and industrial endeavour' (p. 277). The consequence of the guilt attached to this, in Stableford's view, is a dim view of Epicurianism and obesity: 'hedonism always had a bad press in dystopian fiction, since Odysseus first encountered the listless Lotus Eaters' (p. 277). This negative valuation of pleasure subtends the twentieth-century perception of utopianism as ironically conducive to its opposite: the inexorable slide from Eldorado to Helldorado.


This paper presents a method of performing Life Cycle Energy Analysis (LCEA) for the purpose of material selection. The method applies product analysis methods to the evaluation of material options for automotive components. Specifically, LCEA is used to compare material options for a bumper-reinforcing beam on a 1030 kg vehicle. In this analysis, glass fiber composites and high-strength steel beams result in the lowest life cycle energy consumption. This paper also presents a set of life cycle energy terms designed to clearly distinguish between energy consumption occurring during different phases of a product's life cycle. In addition, this paper compares the results of the LCEA method to those of other energy analyses and demonstrates how different methods of varying thoroughness can result in different material selections. Finally, opportunities are identified for extending this type of analysis beyond both automotive components and energy consumption. In particular, this paper identifies the need to develop similar methods for other environmental indicators.


The Supreme Court of Nebraska ruled that the Nebraska Department of Natural Resources did not have the jurisdiction to hear a dispute regarding the withdrawal and transfer of groundwater from an owner's property.


The self-association of copolymers of N-isopropylacrylamide and N-n-octadecylacrylamide (Pnipam-C18) in aqueous solutions was studied by means of time-resolved fluorescence quenching. The discrete domains consist of several polymer chains interacting through their hydrophobic side chains, since the number of aliphatic side chains involved in the microdomain formation (aggregation number) is larger than the number of aliphatic side chains per polymer. By means of titration microcalorimetry, the interaction of the copolymer with surfactants was studied. Strong association between the copolymer and the cationic surfactants N-cetylpyridinium chloride (C1GPyCl) and cetyltrimethylammonium bromide (CTAB) occurs by partitioning of the surfactants in a noncooperative mechanism. Prior to mixed-micelle formation, individual surfactant molecules adsorb to collapsed polymer coils as can be seen from the large exothermal contribution in the enthalpy curves which result from microcalorimetric titration of surfactant into aqueous Pnipam-C18 solutions.


Objective To evaluate the effects of sufentanil and parecoxib sodium combined with total intravenous anesthesia for patients in laparoscopic cholecysteetomy.Methods 120 patients scheduled for laparoscopic cholecystectomy were divided into 4 groups(n=30) according to different pain-killers:Parecoxib sodium 40mg(group P),Sufentanil 0.2 μg/kg(group S),Parecoxib sodium 40 mg +Sufentanil 0.2 μg/kg(group PS),the same dose N.S(group N).ECG,MBP,HR,SpO2,PETCO2 and BIS were monitored during the operation.Anesthsia was induced with propofol and remifentanil by TCI in all patients.During the operation,BIS was kept between 45 and 55 while maintaining cardiovascular homeostasis.20 minutes before the end of operation,different pain-killers were given through vein to the correspond groups while group N was given the same dose of N.S.Mean arterial pressure(MAP),heart rate(HR) were measured 0 min(T0),10 min(T1) after surgery,1 min before extubation(T2),0 min(T3),5 min(T4),10 min(T5) after extubation.Extubation time,the recovery of spontaneous breathing time,recovery time were measured,visual analogue scale(VAS) was recorded 10 minutes,30 minutes,60 minutes,4 hours and 12 hours after extubation.The related complications were observed and recorded during recovery.Results Compared with T0,MAP,HR increased in group N and group P at T1-5(p0.05).Compared with group N and group P respectively,group S and group PS have lower MAP,HR(p0.05).There was no difference in extubation time,the recovery of spontaneous breathing time and recovery time among the four groups.Postoperative early VAS scores were lower in group S and group PS(p0.05).Compared to group S,group P and group PS have lower VAS scores 12 hours after extubation(p0.05).The related complications is less in group S and group PS.Conclusion Parecoxib sodium 40 mg +Sufentanil 0.2 μg/kg for patients undergoing laparoscopic cholecystectomy has hemodynamics stability during recovery process and better postoperative quality when combined with total intravenous anesthesia.


Treatment results of 271 patients with scoliosis are analysed. All patients have been treated according to the system which was worked out by the author and introduced into practice in Azerbaijan. Within this system the conservative and treatment are considered as the components of a single complex of curative measures. Long course of outpatient treatment included the use of corrective deep plaster beds, dynamic corsets of Lion and Charleston type, kineso- therapy, electrostimulation of muscles, drug therapy for metabolism disturbances. Spine deformity stabilization has been noted in 72.3%) of patients including 21.4%) of those in whom the curvature correction was within 1218. In 75 patients (27.7%) the progression of the deformity continued. 46 out of them have been operated on. Plate correctors of the authors design (23 patients), combination of Harrington instrumentation and plate correctors (5 patients), modified Harrington technique (18 patients) were used. The use of plate endocorrectors in patients with the deformities up to 65 enabled to achieve 35 correction. The combination of two endocorrectors was effective in patients with rigid scoliosis and allowed to decrease the loss of the correction. Systemic pre- and postoperative treatment contributed to the preservation of the achieved correction.


Objectives: Describe the steps and activities involved on the mapping processes performed in Hospital Pharmacy Unit, based in the established by national regulations in the area, as strategy for management and quality improvement.
Methods: This is a descriptive study, with components of action research (problem definition, planning and development of action, evaluate the results). The study used the Joint Application Design technique, the Business Process Manegement model and BizAgi Process Modeler® tool for analysis and mapping of processes performed in the management of pharmaceutical care (with Brazilian concept) in this quaternary hospital of the Health's Secretary of the Distrito Federal. The research was conducted between March 2014 and June 2015.
Results: There were identified five processes in drug management (with their sub-processes and activities): programming, drug storage, stores management, distribution and dispensing. As well, In clinical patient management were mapped four processes: drug conciliation, dispensing, pharmaceutical care and hospital discharge patient orientation.
Conclusions: The work process management has an innovative approach, which proposes changes in a participatory manner and adds value to the activities of the institution. The interface built by the Pharmacy with other hospital units and the participation of all employees of the Unit in the mapping process ensured the feasibility of this work. The quality improvement in the performance of Pharmacy duties may contribute to the effectiveness of the Hospital at the Health Care Network on the Distrito Federal.


Pattern formation associated with ionic currents often occurs in biomembranes. The symmetry breaking is interpreted as resulting from an instability driven by the membrane protein segregation. The velocity of a membrane protein under electric field is determined. Two instability mechanisms are sketched in a flat geometry. Critical parameters are determined and compared with experimental data.


PCDDs/PCDFs contamination in soils at a former tannery site in Eastern Massachusetts was found to be widespread. PCDDs/PCDFs concentrations (the sum as (Cl4 – Cl8); tetra-octachloro totals) in the majority of the soil samples (17/32) far exceeded concentrations (10-1000 times) typically found in soils in industrial/urban settings worldwide (1-10 ppb). The distribution pattern of PCDDs/PCDFs in site soils in combination with highly elevated concentrations did not indicate significant influences from off-site sources (e.g. aerial distribution pattern). Widespread chromium contamination in soils often collocated with elevated concentrations of OCDD suggested that both contaminants could be attributed to a common industrial source: the former tannery operations. (total chromium concentrations in the soil samples ranged from 22.2 – 3,457 mg/kg). Elevated PCDDs/PCDFs concentrations predominated by OCDD were most likely attributable to the historical use of pentachlorophenol (PCP) and/or products containing PCP. PCP was likely used as a fungicide/biocide in tannery processes that took place at the site. PCP origins were established through comparison of PCDDs/PCDFs profiles found in soils to those characteristic of PCP products as reported in the open literature (PCDDs/PCDFs profiles found in PCP products are predominated by hexa, hepta and octa congeners). Elevated OCDD concentrations present in site soils may not be solely attributable to historical use of PCP. OCDD, which is the most common PCDDs/PCDFs


The invention relates to a turbocharger hysteresis compensation device based on air compensation of an intake pipe. An independent compressor and a gas storage tank are additionally arranged on an original engine system. The compressor is connected with an output shaft of an engine through an electromagnetic clutch which is controlled through a controller. When pressure in the gas storage tank is lower than first set pressure, the controller controls the electromagnetic clutch to combine, and the compressor starts to work. When the pressure in the gas storage tank reaches second set pressure, the electromagnetic clutch is controlled to separate, and the compressor stops working. When the rotating speed of the engine is low, a turbocharger does not work, and a high-speed solenoid valve is controlled by the controller to directly supply high-pressure air to the intake pipe of the engine.


The precipitation data observed by 160 meteorological stations in the eastern China(the east of 110°E) in more than 100 years were used to study the changes of precipitation and the distribution of extremely more or less rainfall years in the eastern China including north China,Yangtze River Valley and south China region.The method of Z index was used to transform drought and flood area and study the changes of the dry or waterlogged area and the distribution of extremely dry or waterlogged years in eastern China in more than 100 years.Results show that the extremely more rainfall years in more than 100 years distributed evenly in eastern China and the interval was about 20 to 40 years,and the extremely less rainfall years decreased.There was an oscillating period about 40-50 years for the precipitation variation.The precipitation increased significantly in summer,and decreased obviously in autumn.The trend of annual rainfall along the Yangtze River Basin was consistent with the annual precipitation variation in the east China,which illustrated the Yangtze River Basin precipitation contributed significantly to the eastern China,and the secondary one was south China rainfall.There was no obvious increasing or decreasing trend for drought or flood area in the east China in more than 100 years,but there was obvious interannual and interdecadal oscillation.The maximum drought area mainly concentrated before the 1930s in east China,and after 1969 its change trend wasn't obvious.The extremely drought years in the northeast and north China mostly appeared before 1940,and extremely drought years in the Yangtze River Basin and south China distributed evenly.


The Kadomtsev–Petviashvili (KP) II equation possesses a class of line soliton solutions which can be qualitatively described via a tropical approximation as a chain of rooted binary trees, except at 'critical' events where a transition to a different rooted binary tree takes place. We prove that these correspond to maximal chains in Tamari lattices (which are poset structures on associahedra). We further derive results that allow us to compute details of the evolution, including the critical events. Moreover, we present some insights into the structure of the more general line soliton solutions. All this yields a characterization of possible evolutions of line soliton patterns on a shallow fluid surface (provided that the KP-II approximation applies).


New religious anthropology is defined as an aggregate of doctrines and practices that postulated the existence of a particular arrangement of the human being, distinctive from what was recognized as consistent with the scientific approach of the latter half of the 19th century, as well as the human capacity to acquire superhuman powers. The article is focused on the impact of scientific concepts and ideas on the doctrines of new religious anthropology. It reveals that the key role in the formation of new religious anthropology was played by the processes that determined the development of science, such as institutionalization, specialization and mediatization of scientific knowledge. The article suggests a heuristic typology of new religious anthropology, distinguishing Christian, Scientific, Orientalist and Occult types. New religious anthropology is viewed as a means of overcoming the conflict between the science and the religion that was typical for the discourse of the latter half of the 19th century.


48 Table 1Baseline demographics and clinical features of N=45 patients with a primary or secondary discharge diagnosis of pericarditis, from 2019 to 2020 inclusiveCharacteristic N=45 Male: n (%) 27 (60%) No. of admissions (2019 versus 2020) 17 versus 28 Age in years: mean (SD) 53.35 (21.67) Length of Stay in days: mean (SD) 4.67 (6.86) Positive COVID PCR on admission: n(%) 2 (4.4%) Previous diagnosis of diabetes: n (%) 4 (8.9%) Previous diagnosis of hypertension: n (%) 11 Documented smoker: n (%) 1 (2.2) Documented previous cardiac disease history: n (%) 8 (17.8) Exercise level by ASA Grade: ASA 1 13 (28.9%) ASA 2 20 (44.4%) ASA 3 11(24.4%) ASA 4 1( 2.2%) Investigations N = 45 Echocardiogram completed on admission: n (%) 40 (88. 9%) Chest x-ray completed: n (%) 26 (57.9%) CRP completed: n (%) (mg/L) 43 (95.6%) Troponin positive: n(%) 15 (33%) Troponins completed: n (%) 44 (97.8%) 48 Table 2Discharge prescription and documentation of advice giv n, for N=45 patients with a primary or secondary discharge diagnosis of pericarditis, from 2019 to 2020 inclusiveClinical management on discharge NSAIDs + colchicine: n (%) 22 (48.9%) Colchicine only 8 (17.8%) NSAID only 5 (11.1%) Corticosteroid + colchicine: n (%) 4 (8. 9%) Corticosteroid + NSAIDs: n (%) 3 (6. 7%) Corticosteroid + Aspirin (75mg): n (%) 1 (2.2%) Corticosteroid alone: n (%) 1 (2.2%) No medications: n (%) 1 (2.2%) Sports and exercise discharge advice documented: n (%) 6 (13.3%) ConclusionOur study shows a 1.7-fold increase in the number of patients (28 versus 17) presenting with pericarditis in 2020 compared with 2019. Two patients presented with a directly positive COVID-19 nasal PCR swab. Investigations were undertaken in keeping with ESC guidelines, though the documentation of discharge lifestyle and exercise advice was poor.


We give a direct proof of the additivity of the minimum output entropy of a particular quantum channel which breaks the multiplicativity conjecture. This yields additivity of the classical capacity of this channel, a result obtained by a different method by Matsumoto and Yura [quant-ph/0306009]. Our proof relies heavily upon certain concavity properties of the output entropy which are of independent interest.


Submitted for the DFD09 Meeting of The American Physical Society Displacement flows between Newtonian fluids at moderate Reynolds numbers in rectangular channels PRASHANT VALLURI, Imperial College London, HANG DING, University of California, Santa Barbara, PETER SPELT, OMAR MATAR, Imperial College London — Displacement flows between two Newtonian fluids in rectangular channels is studied by numerical and analytical means. Two-stages are clearly seen in the displacement process: first, a core of the displaced fluid is removed by a finger of the displacing fluid with width less than the channel height; then, the film of the displaced fluid adjacent to the wall left behind is then removed via interfacial instabilities that grow spatio-temporally. The shape of the finger dictated by a meniscus in the front and a tail of nearly asymptotic height; the latter is a function of the viscosity and density ratios, Weber number and Reynolds number. This dependence is studied by means of highly resolved direct numerical simulations using the diffuse-interface method. The interface shapes obtained is compared with analytical steady state solutions of the meniscus shapes in the downstream region and the asymptotic film thickness in the upstream region. Prashant Valluri Imperial College London Date submitted: 05 Aug 2009 Electronic form version 1.4


Aiming at the problem of image quality degradation due to scenes change rapidly, an image enhancement algorithm based on scene intelligent identification is proposed. The algorithm sharpen the image detail by using Laplace operator. Determines the change image scene according to the gray value, constructs different gray mapping function, and adjusts gray value range of image adaptively to improve the contrast ratio of image enhancement. By using parallel processing, the algorithm has high execution efficiency, so it can meet the real-time processing of HD video. Experimental result shows that the proposed algorithm has satisfying performance in the rapidly change scene.


In patients with mild cognitive impairment, pathological changes begin in the amygdala (AMG) and hippocampus (HI), especially in the parahippocampal gyrus and entorhinal cortex (ENT). These areas play an important role in olfactory detection and recognition. It is important to understand how subtle signs of olfactory disability relate to the functions of the above‐mentioned regions, as well as the orbitofrontal cortex (OFC). In this study, we evaluated brain activation using functional magnetic resonance imaging (fMRI), performed during the presentation of olfactory stimuli (classified as "normal odors" not inducing memory retrieval), and investigated the relationships of the blood oxygen level‐dependent (BOLD) signal with olfactory detection and recognition abilities in healthy elderly subjects.


A brief history of archaeological research at Gordion Piecing together documentary sources from areas to the east and west of Anatolia, historians agree that in the eighth century BC, central Anatolia was dominated by people who spoke an Indo-European language, Phrygian (Mellink 1991: 621; Muscarella 1995: 92 with refs). From historical sources we also know the location of the Phrygians' capital, Gordion: Quintus Curtius ( Hist Alex III.1–2) states that the city lay on the Sangarios River 'equally distant from the Pontic and Cilician Seas'. Using this description, Gustav and Augustus Korte travelled across Turkey more than a century ago looking for the physical remains of Gordion and Phrygia. They eventually focused on a mound lying adjacent to the Sangarios or modern Sakarya. The mound, now called Yassihoyuk, is large relative to others in the region, and lies in the proper geographical setting for ancient Gordion; a series of artificial mounds or tumuli scattered across nearby slopes provides additional evidence of the settlement's importance.


Jaime Cortez's Sexile frames the experiences of Cuban émigré and transgender activist Adela Vasquez in a comic book that shows how identities are engendered in a matrix of cultural conventions, sexual exchanges, and acts of self-invention, thus illustrating the interrelations between acts of self-fashioning and the work of social transformation.


Ground-state sulphur atoms were generated in a discharge flow system by the rapid reaction between H and H2S: H + H2S = H2+ HS (1), H + HS = H2+ S (2) The resulting chemiluminescence by the B3Σ–u state of S2 is shown to arise (a) by two-body combination of S atoms into level v′= 10; (b) by three-body recombination into lower levels: S(3P)+ S(3P)+ M = S*2(B3Σ–uv′⩽9)+ M (3), S*2= S2(X3Σ–g)+hv(4), S*2+ M = S2+ M (5) with k3=(1.0 ± 0.2)× 1015 cm6 mole–2 sec–1 and k4/k5= 2.0 × 10–7 mole cm–3 for M = Ar at 298°K; also D(S—S)= 101.7 ± 0.4 kcal/mole. The mechanism of the sulphur-catalyzed heterogeneous recombination of hydrogen atoms is studied and discussed.


The conjunction wāw in Biblical Hebrew is commonly regarded as conveying coordination, but also numerous other meanings. The issue of the multiple meanings of the conjunction wāw has attracted the attention of Biblical Hebrew (hereafter: BH) scholars over the years. Their discussions of this issue are presented in dictionaries, grammars, and several studies. In the present article I do not deal with all the meanings attached to the conjunction wāw in BH down the ages and their justification, but only one of those meanings, namely the wāw of concomitance or accompaniment, commonly named after the Arabic term wāw al-maʿiyyah.


The present invention discloses a preparation of D- xylose utilization phosphoric acid, L- arabinose method. After binding process cane sugar, the phosphate precipitate is dissolved by an acid treatment; bagasse, sugarcane leaf pith or as raw material, the raw material hydrolysis, was phosphate precipitation, purification, to give D- xylose, L- arabinose must be used in the process of sugar cane juice processing aid was added to the re-use of resources. This method facilitates the sugar cane industry environmental protection and resource utilization, hydrochloric acid or sulfuric acid is currently produced using xylose comparison, do not produce an acid hydrolysis pollution, simple operation process, high yield of sugar, low cost, suitable for industrial production, and solve the bottleneck problem of environmental pollution in the production of xylose.


acid residues were similar to those in fractionated human partoid saliva (Bennick & Connell, 1971), with the exception of cysteine, threonine and tyrosine, which these workers did not identify. The presence of rhamnose in dental calculus suggests materials of bacterial origin. The results also indicate that in addition to glycoproteins, another component, acid glycosaminoglycans are present in dental calculus but not in salivaryduct calculus. This was clearly shown by both electrophoretic pattern and the extinction band at 825cm-' characteristic of C-0-S groups in chondroitin sulphate (Brimacombe & Webber, 1964). The finding is regarded as a confirmation of previous results and suggests that glycosaminoglycans as well as the salivary glycoproteins could be involved in the initiation of calcification of oral calculus. Although the source of the former has not been fully investigated, it is possible that they derive as products of the breakdown of gingival tissue in associated periodontal disease. If so, the absence of these substances from salivary-duct calculus may be due to the relatively limited degree of inflammation and tissue destruction during stone formation. Of particular note is theextinction band at 1240cm-' in both materials due to an S=O group, because of reports of other workers on the presence of sulphated glycoproteins in saliva (Schrager & Oates, 1971) and gastric mucosa (Snary &Allen, 1972). It is therefore evident that the generally accepted structural differences between these two classes of compounds requires further clarification.


A "kinder and gentler" nation was promised by George Bush in his 1988 acceptance speech to the Republican convention. Within a few years and perhaps with this in mind, Osby and colleagues (page [3840][1]) of the Nordic Lymphoma Group designed the 2-by-2 study reported in this issue of Blood,


Objective: We investigated the effects of angiotensin II (Ang II) type 1 (AT1) receptor blocker (ARB) olmesartan on impaired endothelial progenitor cells (EPCs) and renal degeneration through angiotensin converting enzyme 2 (ACE2)/ Ang-(1–7)/Mas receptor (MasR) axis in salt-loaded spontaneously hypertensive rats (SHRs).
Methods: Wistar-Kyoto/Izm (WKY) rats and SHR/Izm were salt-loaded. SHRs were treated with vehicle, hydralazine, olmesartan, and olmesartan plus MasR antagonist A779 for 2 weeks. Peripheral blood mononuclear cells were isolated and subjected to flow cytometric analysis to determine the number of circulating EPCs. To evaluate the mechanisms of effects of olmesartan on renal degeneration, we investigated morphological changes and expression of ACE1, ACE2, MasR, VEGF, eNOS, NAD(P)H oxidases, HIF-1α, CTGF and TGF-β1 proteins in the kidneys.
Results: In SHRs, olmesartan was found to significantly increase EPC number and improve glomerulosclerosis; effects which were blunted with MasR antagonist A779. Expressions of CD34, P-eNOS, ACE2 and MasR proteins were significantly lower in SHR kidneys than in WKY rats. Olmesartan was found to significantly upregulate decreased expression of these proteins, this was blunted with A779. Expressions of VEGF, ACE1, NAD(P)H oxidases, HIF- 1α, CTGF and TGF-β1 were significantly higher in the kidneys of SHRs than in WKY rats. Olmesartan significantly downregulated their increased expression, an effect which was also blunted with A779.
Conclusion: Olmesartan improved impaired EPC formation and renal degeneration through the ACE2/Ang-(1– 7)/MasR axis in salt-loaded SHRs, suggesting that the ACE2/Ang-(1–7)/MasR axis represents a potential target for hypertension.


This paper describes the concept, design and development of a new highly flexible diagnostic system for diesel powered equipment. An application involving an Ingersoll-Rand compressor and electrical generator for aircraft ground support is reviewed. The diagnostic system consists of three microprocessor based modules that communicate with each other. These modules provide the function of performance monitoring, data logging, fault diagnostics, simulation, calibration and operator interface.


Science fiction literature is commonly disregarded by main stream literature. Gratuitously: e.g. H. G. Wells, Isaac Asimov, Robert A. Heinlein, Ray Bradbury and Arthur C. Clarke can hardly be insignificant scribblers ... In late 1960s, in 1968 to be precise, Zhongguo Shibao《中國時報》China Times published Zhang Xiaofeng's 張曉風 novel Panduna《潘渡娜》Pandora. It is regarded as the first example of Taiwanese science fiction prose ever written. In the 1970s and 1980s science fiction literature experienced the turbulent progress in Taiwan: sci-fi literature was published by newspapers, periodicals and publishing houses, sci-fi magazines were established, the first competitions for authors of science fiction literature were announced, the first prizes were awarded. In addition, the first critical works were written and sci-fi stars such as Huang Hai 黃海 and Zhang Xiguo 張系國 appeared. The twenty years of development of Taiwanese sci-fi came to a halt in the early 1990s with the boom of science fiction cinema. The beginning, development and decline of science fiction literature in Taiwan as a definite phenomenon can therefore be analysed and described. Its history is almost completed, thus we can not only elevate, but also compare her development with the most influential science fiction literature in the world: American science fiction. A description of the development and a comparison are the main purpose of this paper.


A high average power, optical parametric oscillator (OPO) based system has been developed for the purpose of generating output in the 3-5 /spl mu/m mid-IR band. The system uses a cw diode array-pumped, Nd:YAG master oscillator power amplifier (MOPA) as the pump source and two tandem OPOs for wavelength conversion to the mid-IR. A Type II degenerate KTP OPO was used to convert the pump beam to 2.13 /spl mu/m and a Type I near (ZGP) OPO was used to generate broadband radiation in the 3.7-4.1 and 4.4-4.8 /spl mu/m wavelength range.


Solutions of wind-tunnel and entry-flight flow around the vehicle are obtained from the Navier-Stokes equations coupled with the chemical species continuity equations if needed. The time-iterative method employs several techniques: shock fitting, chemistry-split ADI and an algebraic grid in conformal spherical-polar space. Sensitivities of the results to numerical parameters and to frozen, equilibrium and finite rate reactions are investigated in the forebody computation. Quantitative results are obtained for the shock layer and the near wake for the entire vehicle corresponding to both ground test and flight conditions. Complex flow characteristics are analyzed on the basis of the complete flowfield over the aerobrake and simplified afterbodies. The method is stable and cost effective, and has yielded shock locations and wall pressure distributions which are in good agreement with wind-tunnel data.


Anemia is a very common problem in obstetrics and perinatal care. Iron deficiency and related anemia during pregnancy are highly prevalent both in developed and underdeveloped counties and even within a country in different geographical regions with different etiologies such as standards of living. To find the differences in the prevalence and causes of IDA as well as contribution of different etiological factors in promoting IDA in pregnant women. A sample size of 280 was calculated and the study was carried to analyze the frequency of IDA at Khyber Teaching Hospital and the impact percentage of different etiological factors in development of IDA in pregnant women of age less than 40 years and without any comorbidities. Following causes were identified; low socioeconomic state, food quality, education level, number of previous pregnancies and stage (trimester) of pregnancy. Out of 280 pregnant women 185 were found normal Hb levels, 84 having mild anemia ,11 were found to have mild anemia. 95 women had microcytic anemia. Additionally, 173 out of total anemia pts were found to have monthly income of less than 20,000 being the most predictable factor. Third trimester was mostly credited for IDA in pregnancy. Similarly triplet, followed by twin and then singleton pregnancy was responsible for IDA. Anemia has serious longterm effects on the health of mother as well as fetus besides obstetrics complications.


This study examines the effects of vertical error in digital elevation models (DEMs) on the determination of flow-path direction. Flow-path data are widely used in hydrologic modeling applications, but the sensitivity of flow-path algorithms to error in DEMs has not been addressed in a systematic fashion. This study employs a simulation-based approach in which numerous realizations of an error-free DEM are produced that conform to different assumptions about the statistical and spatial properties of error. Results suggest that extreme caution should be used when employing flow-path data derived from DEMs, especially if there is reason to suspect that vertical error is large or positively correlated with terrain slope. Flow-path data are least reliable in areas of low slope where even small amounts of error can induce significant changes in flow-path direction. In some cases, the level of reliability is only marginally better than the level that would be obtained if flow paths were assigned on a random basis.


A frequency and polarization reconfigurable patch antenna is presented in this paper. The antenna consists of a circular patch surrounded by four sector-shaped patches. Four pairs of varactor diodes are introduced to bridge the gaps between the circular patch and the sector-shaped patches. By adjusting the reverse bias voltage of the varactors, the proposed antenna can switch between linear polarization (LP), right-hand circular polarization (RHCP) and left-hand circular polarization (LHCP). Furthermore, the operating frequency of each polarization state can be independently tuned. The results indicate the proposed antenna with a continuously tunable frequency range from 1.82 to 2.28 GHz in LP states, and from 1.88 to 2.25 GHz in either RHCP or LHCP states. Meanwhile, stable radiation patterns are achieved for all states.


The invention relates to a laser coating for performing laser for an identification card. The laser coating comprises the following raw components in parts by weight: 2 to 10 parts of hexamethylene diisocyanate tripolymer, 10 to 40 parts of bi-functional isocyanate, 50 to 60 parts of macromolecule dihydric alcohol, 4 to 8 parts of chain extender, 10 to 30 parts of solvent, 0.1 to 0.3 part of catalyst, 3 to 6 parts of neutralizer, 3 to 15 parts of hydroxyethyl methylacrylate, 5 to 30 parts of 2-hydroxypropyl acrylate, and 240 to 280 parts of deionized water. The laser coating provided by the invention is manufactured by performing catalyzing and chain extension through macromolecule polyalcohol and then emulsifying and dispersing; and the laser coating is high in physical property and chemical property, and high in computability regarding to a plurality kinds of ink. Therefore, the laser coating can be directly subjected mould pressing laser, and as a result, the process of individually cementing a laser pattern layer on the identification card is reduced, the manufacture process is simplified, and the production cost is decreased.


Educational games can enhance students' motivation to learn. This article reports and reflects on the development of the educational games and board games. The author proposes a new concept educational board games which has the characteristics of both educational games and board games. By game design, test design, the author has discussed the possibility of applying educational board games into teaching. Can Anne Go upstairs? Is the first game on senior school English classroom teaching that is readily available for its description of the cards and its rule of the game. The results have put forward its framework and try to test the promotion in the classroom. Key words—educational board games, senior high English teaching, curriculum-based game-design


PurposeThe purpose of this paper is to examine the relationship of the interaction effect of perceived organizational support (POS) and self-efficacy (SE) with work engagement (WE) within the primary education industry.Design/methodology/approachThe paper relies on structural equation modeling (SEM) with AMOS (V.22) to test and resolve the conditional hypothesis that fusion of POS and SE is necessary for WE.FindingsThe scale of effect of POS on WE depends on SE; hence, the assumption of nonadditivity is achieved. Precisely, the interaction of POS and SE is necessary for WE.Research limitations/implicationsThe study was based on a single research methodological approach, namely quantitative research methodology, which could have been affected the outcome of this investigation. Future studies could investigate WE interaction model through qualitative lens in order to provide a triangulation opportunity. Moreover, the findings from the current study are cross-sectional, and data were collected at a snapshot. Therefore, future research should consider the multiplicative effects studied in this paper across time.Practical implicationsAttempts to heighten WE levels, among government primary school teachers in Uganda, would require that management regularly ventures into finding a more practical and feasible fusion of POS with SE in order to provide significant levels of WE among employees of primary education industry.Originality/valueThis is the first study that tests the interactive effects of POS and SE on WE in Uganda's primary education industry.


It has long been suggested that moves toward equality can have serious disincentive effects and, after a point, lead to unacceptable losses in real income.' We will now offer some theoretical grounds for believing that an approximation to equality achieved via the traditional instruments-transfer payments and progressive taxation-will cause an income loss far more serious than many of us have realized. We will prove that under a set of reasonable assumptions, any attempt to guarantee absolute equality of incomes using only progressive income taxes and transfers for the purpose must, at least in theory, reduce society's output to zero! However, we do not conclude from this that the search for very much increased equality is quixotic. Rather, we take this as a criticism of the means so far used for the purpose. What is called for is an exercise in imagination and ingenuity, to find some alternative ways to go about this quest. We will then show explicitly and examine an alternative procedure that, at least in theory, can achieve any desired degree of equality without necessarily exacting a serious loss in output, and will end by discussing briefly the possibility of practical approximations to such an arrangement.


Purpose – This study aims to provide insight on the meaning of communication overload as experienced by modern academic librarians. Communication is the essence of reference librarianship, and a practically endless array of synchronous and asynchronous communication tools (ICTs) are available to facilitate communication.Design/methodology/approach – This study relied on a phenomenological methodology, which included nine in‐depth interviews with academic librarians. The interviews were transcribed and analyzed using RQDA, a qualitative analysis software package that facilitates coding, category building, and project management.Findings – Seven themes about librarianship emerged from this research: attending to communication abundance, librarians of two types, instruction not reference, twenty‐first century librarianship, user needs, trusted methods: filter not retrieve, and self‐impact. The shared meaning of communication overload among these librarians is that it is a problem when it detracts from or hin...


As various resources have been developed by human-beings in river basins and the conflict between human and land has been increased,the research on man-land relationship areal system in a river basin becomes important.The paper constructed evaluation indexes system for evaluating the man-land relationship areal system in river basins by selecting 40 indicators related to socio-economic sub-system and resource-environment sub-system.After using analytic hierarchy process to determine index weight,the coupling status of the man-land relationship areal system in the Weihe river basin from 1996 to 2006 has been analyzed empirically by using a dynamic coupling model for the harmonious development based on the system theory.The results show that the socio-economic level in the main stream basin of the Weihe River has increased its volatility from 1996 to 2006 accompanied with the fluctuations of resource-environmental state.The resource-environment sub-system shows repeated fluctuations with deterioration and improvement in turns.The research shows that the coupling degree in the man-land relationship areal system increases rapidly in the Weihe River basin.At present,the man-land relationship areal system in the Weihe River basin is at an over-exploitation phase.Also,the crisis of resource-environment is in the incubation period.If we do not pay attention to environmental protection and go on to overexploit resources,the situation will get worse quickly.At that time,the growth of economy and the increase of consumption of resources will overwhelm the resource-environment system and lead to continuous decrease of environmental quality.Then the relations between the two systems will be deteriorated,and also the socio-economic development will be constrained.The system will enter a phase of negative growth.So it is crucial to adopt proper socio-economic development mode to realize the coordinated development in the Weihe River basin.


The serious charging effect of polymer film with a thickness of the order of microns under the radiation of high-energy transmission electron beam, on the reliability of the micro-nano electronic device in electron microscopy detection is investigated. The charging effect of the polymer film is numerically calculated in this paper. The scattering process is simulated by the Monte Carlo method. The elastic scattering is calculated with the Rutherford scattering model. The inelastic scattering is simulated with the fast secondary electron (SE) model and the Penn model. The transport, the capture, and the recombination process of the charges are treated with the finite difference method. The fourth-order Runge-Kutta method is used to solve the trajectory of the emitted SEs. The dynamic distributions of the net charge, the built-in electric field, the surface emission current, and the transmission current are investigated, and the influence of the film thickness and the beam energy on the charging characteristics are analyzed. The results show that due to the emission of electrons near the sample surface, the distribution of the net charge in the sample is first positive and then negative along the incident direction. In addition, under the irradiation,higher charge quantity is deposited in the sample, and the net charge density increases gradually. However, with long-time irradiation, the deposited electrons transport to the surface under the action of built-in electric field which reduces the surface net charge density. Therefore the net charge density tends to a stable value. The space potential is positive in the surface and negative inside the sample. Therefore some emitted SEs return to the surface, resulting in the electron beam-induced current. With the irradiation, the positive surface potential increases and tends to a stable value. Hence the actual surface emission current decreases to a stable value and the sample current increases to a stable value. The sample current remains unchanged due to the weak charging strength. Increasing the film thickness leads the transient time to increase, which contributes to the decline of the surface potential and the increase of the actual emission currentand sample current. The increase of the beam energy causes the transmission current to increase and the sample current to decrease. In addition, it reduces the positive surface potential and the actual surface emission current accordingly. The results conduce to the decrease of the charging effect of the polymer film under the radiation of high-energy electron beam in the electron microscopy.


Objective:To investigate the expression of CD40 in pulpitis,and to elucidate its potential role in the development of pulpitis. Methods:We detected the expression of CD40 in acute and chronic pulpitis using immunohistochemical staining method. Results:There was no CD40 expression in normal pulp tissue. In acute and chronic pulpitis tissue,CD40 was immnohistochemically expressed in macrophages and plasma cells,which was much stronger in chronic pulpitis. Conclusion:CD40 may play important roles in the development of pulpitis.


Congo red (CR) is a stable anionic diazo dye that causes allergic reactions with carcinogenic properties. The rapid removal of CR using cation-incorporated nanohydroxyapatite (pristine HAp: X (X = Fe, Ni, Zn, Co, and Ag)) was investigated. The pristine and cation ion-doped HAp adsorbents were coprecipitated and subjected to hydrothermal and ultrasound treatments and subsequent microwave drying. The dopant ions significantly engineered the crystallite size, crystallinity, particle size (decreased 38–77%), shape (a rod to sphere modification by the incorporation of Ag+, Ni2+, and Co2+ ions), and colloidal stability (CS) of the adsorbent. These modifications aided in the rapid removal of the CR dye (98%) within one minute, and the CR adsorption rate was found to be significantly higher (93–99%) compared to previously reported rates. Furthermore, the kinetic, Langmuir, Freundlich, and DKR isotherms and thermodynamic results confirmed that the CR adsorption on the HAp was due to the strong chemical adsorption process. The order of the maximum CR adsorption capacity was Fe-HAp > HAp > Ag-HAp > Co-HAp > Zn-HAp. Whereas the CR regeneration efficiency was Fe-HAp (92%) > Ag-HAp (42%) > Ni-HAp (30%), with the other adsorbents exhibiting a poor recycling efficiency (1–16%). These results reveal Fe-HAp as a potential adsorbent for removing CR without the formation of byproducts.


Higher education in business has had an interesting, albeit brief, history in the United States (McKenna, 1989). The forces of change that have impacted collegiate level business education have, in some instances, been evolutionary. In other instances, the academy has responded to criticism leveled by respected authors in the popular and academic press (c.f., Jennings, 1994; Putka, 1995). Finally, in a third set of instances, a more planned and structured change has resulted from the actions of the principal accrediting body, the American Assembly of Collegiate Schools of Business (AACSB). In the Spring, 1985 issue of the California Management Review Earl Cheit (then Dean of the School of Business at U.C. Berkeley) summarized and responded to the criticisms and changes that were impacting collegiate level business education. Cheit noted that the early roots of business education grew out of a highly vocational, skill focused training regime. It was his belief that only with the publication of the Pierson (1959) and Gordon and Howell reports (1959) did business education begin to find some legitimacy, within the University. Several writers have also observed the crucial importance of prestige/legitimacy in the academic community (see Caplow and McGee, 1958; Thompson/1967). The quest for legitimacy was quite implicit in the reports of Pierson (1959) and Gordon and Howell (1959). Basically, academic prestige is a way of acquiring power and the fostering of prestigious images is widely evident among universities (Thompson, 1967). However, with the development of academically legitimate AACSB accreditation standards, a new concern has arisen, one involving the relevancy of business school education. This issue ultimately led Cheit to conclude that business schools face a dual responsibility. On the one hand, they must give consideration to the academic audiences of which they are inevitably a part, while on the other hand, they also must seek to meet the often conflicting needs of professional audiences for whom they train students. Cheit's concern and later the concern of Porter and McKibbin (1988) and Jennings (1994) was that business schools had become so successful academically and so far removed from their professional constituencies that they failed to understand and address problems of concern to business. In other words, business schools were training graduates to be technical specialists with quantitative and theoretical tools but with little capacity to really do the hands-on job of leading people. In order to better understand this lack of relevancy in collegiate business education, Cheit proposed two explanatory models. TWO MODELS OF BUSINESS EDUCATION Cheit maintained that business schools, being accountable to both professional and academic audiences, should consider the simultaneous pursuit of two models: academic and professional. The academic model treats the field of business as a science; its objective is to develop in students habits of mind and analytic competence that will be useful in analyzing future problems that are today unknown. In this model, the function of a manager is to allocate the organization's resources to maximize long-term value using sophisticated decision-making models. Faculty who subscribe to the academic model emphasize graduate instruction and have little relationship with the business community. Alternatively, the professional model is essentially "field driven," or responsive to the perceived needs of the business community. This model challenges faculty to work with students in helping them deal with developing judgment in resolving complex and unstructured practical problems. In the professional model setting, linkages with the professional community are critical and faculty regularly pursue consulting and executive development activities. Research, while not as critical as in the academic model, supports the investigation Of applied problems of current concern to managers. …


The implantable CNT-based sensor is suggested to detect CSPGs which is main compositions of glial scar which inhibit the axonal regeneration after spinal cord injury. The suggested sensor is fabricated using spin-coated polyimide and patterned by MEMS process. Multiwalled CNT networks are formed by air spray method on the interdigitated sensor electrodes as the sensing element of CSPGs. The feasibility of the fabricated sensor is successfully confirmed in vitro by measuring the resistance change of CNT networks versus various CSPGs concentrations. The results show that the suggested sensor accurately detects the low CSPGs concentration to sense the regeneration-inhibitory effect of CSPGs.


The mechanisms by which moisture interacts with the Himalayas largely determine the amount of precipitation in Himalayan basins. While many recent studies have focused on mechanisms of independent precipitation events, climatological studies that are essential for a complete understanding of precipitation‐generating mechanisms are limited. This work presents synoptic regimes, which produced precipitation across all seasons in the Western Himalayas (WH) from 2000 to 2018. Using the k‐means clustering algorithm, seven clusters are employed to define relatively mild, moderate and wet regimes, showing distinct seasonality and a synoptic meteorology. We found positive precipitation anomalies at lower elevations in monsoonal regimes (M1, M2 and M3) but at higher elevations in winter (W1 and W2) and transitional regimes (T1 and T2). Moist monsoonal regimes are associated with dynamical interactions between low‐level tropical cyclonic circulations and mid‐level subtropical troughs. Synchronous primary and secondary cyclonic circulations facilitate tropical moisture influx and obstruct the further northward movement of cyclonic circulations, which results in large magnitudes of precipitation at lower elevations in monsoonal regimes. On the other hand, winter regimes exhibit intense western disturbances, which enable orographic ascent of tropical moisture towards higher elevations. Despite weaker dynamical interactions, a stronger thermodynamical instability and a steeper terrain gradient trigger deep convection at higher elevations in transitional regimes. Overall, monsoonal regimes account for 52% of rainy days, whereas winter and transitional regimes account for 20 and 28%, respectively. We present a methodology that identifies hotspots of anomalous precipitation over vulnerable higher elevations by tracking atmospheric variables in Delhi. Our results illustrate the dynamical and thermodynamical interactions responsible for precipitation and highlight the significant contribution from nonmonsoonal regimes to the precipitation across higher elevations in the WH.


Purpose – The purpose of this paper is to describe how healthy performance of facilities can be monitored and performance data delivered as information flow according to specific user groups' needs.Design/methodology/approach – The context of performance in facilities is described, and a tool for the collection of performance data and communicating the data as relevant information for the facility management (FM) and other stake holders is developed.Findings – Various user groups are utilizing the same performance data to ensure optimal and healthy conditions. The integration of performance data to deliver meaningful and exploitable results for each user requires collection of the relevant data, compilation of data into information, and delivery of user specific information to the correct instance. A performance sensing system with data management was developed into a FM tool for this purpose.Practical implications – FM is enabled to real time decision making by sensor‐based performance monitoring.Origina...


In this paper,taking the computer system as the research object, the computer power cord, video cable and optical drive bus are respectively injected with pulse signal, the current probes and near-field probes are used to measure the induced voltage on the computer connection cable ,the seams and vents of the housing. When a pulse signal is injected into a cable, video cable, the computer power cord, keyboard cable, mouse cable, and monitor power cord also have corresponding pulse signals. Based on this measurement,because of the common-mode current,useful computer information is also present on the above-mentioned cables,the seams and vents of the housing,and is being transmitted. Using this injection method, it can also be used to diagnose cables and components with strong radiation capability or disturbance pick-up capability in computer systems.


Background Peripheral artery disease is a major socioeconomic challenge in the diabetes mellitus community and non‐surgical treatment options are limited. As remote ischemic conditioning (RIC) improves vascular function and attenuates ischemia‐induced tissue damage, we investigated the efficacy of RIC on vascular and neuronal function in type 2 diabetes mellitus patients with peripheral artery disease. Methods and Results We enrolled 36 type 2 diabetes mellitus patients with moderately reduced toe pressure (40–70 mm Hg) in a randomized sham‐controlled double‐masked trial. Patients were allocated to 12 weeks once daily upper arm cuff‐based treatment of either RIC treatment (4 cycles of 5‐minute ischemia followed by 5‐minute reperfusion) or similar sham‐device treatment. Primary outcome was transcutaneous tissue oxygen tension of the instep of the feet. Secondary outcomes were aortic pulse wave velocity, toe pressure and toe‐brachial index. Tertiary outcomes were markers of peripheral and autonomic nerve function. We enrolled 36 patients (83% men). Patients had a mean (SD) age of 70.7 years (6.8), diabetes mellitus duration of 18.4 years (8.3), HbA1c (gycated hemoglobin) of 59.7 mmol/mol (11.2). Eighty percent had peripheral symmetrical neuropathy. The mean difference in change of transcutaneous tissue oxygen tension from baseline between the RIC and sham‐treated groups was −0.03 mm Hg ([95% CI −0.1; 0.04], P=0.438). RIC did not elicit any change in additional outcomes. Three patients experienced transient skin petechiae in the treated arm. Conclusions Long‐term repeated remote ischemic conditioning treatment have no effect on tissue oxygenation, vascular or neuronal function in patients with type 2 diabetes mellitus and moderate peripheral artery disease. Clinical Trial Registration URL: http://www.ClinicalTrials.gov. Unique identifier: NCT02749942.


Objective: To determine the antioxidant and anti-inflammatory activities of the solid powder extracted from the ethyl acetate fraction of the flower Hibiscus vitifolius L.
Methods: The flower extract assessed for antioxidant activity using the 1,1–diphenyl-2-picryl-hydrazile (DPPH) radical scavenging assay and the reduced power assay was performed using the Ferric Reducing Capacity (FRC) assay. In vitro anti-inflammatory activity was assessed using human peripheral blood mononuclear cells (PBMC) induced by lipopolysaccharide (LPS) to test the production method of nitric oxide (NO).
Results: The solid powder extracted from the ethyl acetate fraction of the flower Hibiscus vitifolius L showed good antioxidant activity in the scavenging DPPH radicals and the FRC assay compared to the standard sample. This powder sample also showed good anti-inflammatory activity in cell viability (LPS induced PBMC) assay and nitric oxide (NO) assay.
 Conclusion: These results suggest that the powder sample extracted from the ethyl acetate fraction of the flower Hibiscus vitifolius L has substantial antioxidant and anti-inflammatory activity.


SUMMARY: The effects of a high salt diet on renal destruction and the therapeutic effects of amiloride (Na+/H+ exchanger inhibitor) and furosemide (Na+K+/2Cl− exchanger inhibitor) were examined in 5/6‐nephrectomized rats fed a high salt diet. A simultaneous analysis of the effects of a high salt intake on the renal expression of Na+/H+ exchanger‐1 (NHE‐1), transforming growth factor‐β1 (TGF‐β1) or platelet‐derived growth factor‐B (PDGF‐B) mRNA was performed in this model. the 5/6‐nephrectomized Sprague‐Dawley rats were given a diet containing 8 or 1% sodium chloride for 5 weeks. This high salt diet accelerated the elevation of blood pressure and aggravated both glomerulosclerosis and interstitial fibrosis in 5/6‐nephrectomized rats. the daily administration of amiloride was found to be protective against the elevation of blood pressure, glomerular hypertrophy and the aggravation of renal histology which were induced by a high salt diet. the expression of TGF‐β1 and PDGF‐B mRNA was up‐regulated by a high salt diet, but the expression of NHE‐1 mRNA was not. the overexpression of TGF‐β1 and PDGF‐B mRNA was reduced by the daily administration of amiloride but not by furosemide. In conclusion, the destructive effects of a high salt diet on the kidneys may be mediated through hypertension, glomerular hypertrophy and the overexpression of the growth factors. Amiloride may thus be more protective for high salt induced renal aggravation than furosemide, although the expression of NHE‐1 mRNA did not show any substantial increase due to a high salt diet.


The article studies social media as a communication platform during the war. The set of mass communication tools to meet the audience's information needs, coordination of volunteer activities, popularization of the volunteer movement, and involvement of the Internet community in helping the Armed Forces were analyzed. During the Russian-Ukrainian war, social media became the platform where the exchange of information takes place much faster; good analytics could be found quickly, which were pushed out of the information space. Also, social media have taken on the role of a platform where you can coordinate work, unite society around important issues, organize assistance to the army, and report on the needs of the Armed Forces. That is why the presentation of volunteering in social media is considered a relevant research topic because the presentation of volunteering in social networks has generally changed the content of blogging. Stars of show business, politicians, people of art, and educational and scientific fields have done incredible things with social media's help in organizing military aid. We believe that the volunteer movement through social media has expanded the functions and role of these communication platforms, demonstrating the importance of Internet communication and the effectiveness of using the latest media tools in wartime. The historiography of the study covers the works of Ukrainian and foreign scientists. Among them are L. Horodenko, V. Hvozdiev, B. Potiatynyk, G. Synorub, A. Rohulskyi, D. Rashkoff, and others. The war situation in Ukraine has opened up new requests for blogging activities, exceptional support, and initiation of volunteering. The content of bloggers is now 80 percent filled with the topic of war. The presentation of volunteer work is considered individually and collectively on behalf of foundations and public organizations. We believe that a significant advantage of an active volunteer movement in social networks is fast communication, which contributes to the rapid resolution of crucial tasks. Keywords: social media, volunteering, information, war.


The present invention relates to a dual channel asynchronous pipeline SAR ADC. SAR ADC system according to the present invention is a clock signal and the clock delay signal level of by creating a META signal that determines the output of the comparator to a high logic level of the comparator when the not the READY signal indicating the completion of operation of the comparator output between the steady-state It may include metastable state detection circuit to reduce output due to an error. Also it can be implemented to share one comparator in order to minimize the offset mismatch between the first stage and the second stage two with no additional correction techniques to channel SAR ADC. In addition, the second stage SAR ADC may use a DAC of the R-2R resistance based to minimize switching power consumed in reducing the number of the capacitor chip area and the DAC is used, using a technique that determines the least significant two bits.


In this paper a novel pumping strategy, based on the use of a single drop of ferrofluid as the active mass and an analog driving system, is presented. The absence of mechanical moving parts and solid-inertial masses provides high reliability and the possibility to implement the pumping mechanism on pre-existing channels. Experiments dedicated to estimate the average amount of pumped liquid, the drop pressure and the capacity as function of frequency and amplitude of the driving signals, have been performed. Other measures to estimate the average amount of pumped liquid and the maximum drop pressure for a different size of the outlet tank and the amount of pumped liquid in vacuum, are achieved.


In the late sixties and early seventies students in large numbers left their residence halls to live off campus. In 1973 there seems to be the beginning of a reversal of this trend, with more students re questing to stay another year, and more freshmen and transfer stu dents showing a positive desire to live in college dormitories. The implications of these shifts in student preferences are important, not only for the fiscal stability of institutions which have large bonded indebtedness for dormitory construction, but also for the educa tional values which may inhere in college residence. "Educational values" can cover a multitude of things, and the personnel of residence halls are apt to defend as educational any program they inaugurate, whether it be a chess tournament, a lec ture on ESP or Human Sexuality, or an address by James Van Allen on outer space. On some campuses, students are grouped, or group them selves, in accordance with academic or other common interests. On other campuses, there is opposition to such groupings on the grounds that students prefer diversity, not homogeneity: they come to college to meet different kinds of people. A thesis popular with many students, as well as residence hall staff, is that freshmen should be placed in situations of diversity, but that options for homogeneity should be available to upperclass students.


This study based on characteristics of network traffic is significant, it can improve network design, improve network performance, is often used in the abnormal traffic detection and so on. In this paper, the significance of abnormal flow monitoring is design based on an analysis of network behavior anomaly traffic monitoring system, the system for use of the network traffic characteristics of network attacks detected has a good prospect.


Thoughts of literary anthropology have remarkable aesthetic value in Frye′s symbolization theory.He breaks the boundaries between literary criticism and other fields.Frye regards ceremony as literary narration and dream as literary meaning.He regards myth as a language communication between ceremony and dream.The origin of literary narration and meaning in his theory provides us a new view of literature research.


Unsolicited rating agencies convey information about potential borrowers to investors whether or not the borrowers want it to do so. However, as they do this without the consent of the borrowers, they are not paid for this service by the borrowers. It is often argued that this is done to build reputation. In this paper, we develop a model that identifies the scenarios where unsolicited ratings can co exist profitably with solicited ratings. JEL Classification No. G140, G200, G290


Redundant protection, tariffs that exceed the domestic import-price differential, is an important feature of nineteenth century U.S. tariff history and remains a common practice in many developing countries. This paper develops political-economy models of the tariff-setting process when the world price of the importable product is stochastic. The optimal endogenous tariff may involve redundant protection even if agents are risk neutral. These political-economy models also permit us to assess the comparative static effects of changes in the mean-preserving spread of the world price under differing assumptions about the political process. Copyright 1993 by Oxford University Press.


We consider the tails of probability density functions (PDF) for different characteristics of velocity that satisfies Burgers equation driven by a large-scale force. The saddle-point approximation is employed in the path integral so that the calculation of the PDF tails boils down to finding the special field-force configuration (instanton) that realizes the extremum of probability. We calculate high moments of the velocity gradient $\partial_xu$ and find out that they correspond to the PDF with $\ln[{\cal P}(\partial_xu)]\propto-(-\partial_xu/{\rm Re})^{3/2}$ where ${\rm Re}$ is the Reynolds number. That stretched exponential form is valid for negative $\partial_xu$ with the modulus much larger than its root-mean-square (rms) value. The respective tail of PDF for negative velocity differences $w$ is steeper than Gaussian, $\ln{\cal P}(w)\sim-(w/u_{\rm rms})^3$, as well as single-point velocity PDF $\ln{\cal P}(u)\sim-(|u|/u_{\rm rms})^3$. For high velocity derivatives $u^{(k)}=\partial_x^ku$, the general formula is found: $\ln{\cal P}(|u^{(k)}|)\propto -(|u^{(k)}|/{\rm Re}^k)^{3/(k+1)}$.


This study presents auxiliary support techniques for tree selection strategies based on the spatial structure indices and three competition indices in secondary forests, and discusses the importance of tree competition in forest management. The spatial structure parameter in the structured management is used as a quantitative index—the uniform angle index and three competition indices are used in the design of the algorithm for selective thinning for secondary forest. Based on the target tree-based management principles, simulation of selective thinning was carried out using GIS and C# programming languages. Data for this study were collected from experimental sample plots at Jilin Wangqing Forestry Bureau in China. The simulation results strongly support the use of auxiliary technology for scientifically selecting trees for thinning, avoiding the subjectivity of the traditional manual selection. Selection is largely based on the uniform angle index and competition index. Hegyi's competition index and its improved version used in the algorithm provided almost identical simulation results, i.e., thinning intensities suggested by these indices for the first sample plot are 21.8% and 21.5%, respectively, and for the second plot are 21.3% and 21.1%, respectively. Thus, one of these competition indices can be used to select trees for thinning. The comprehensive competition index (CCI, a combination of an improved version of Hegyi's competition index with tree species mingling) can avoid the selection of individual trees with high mingling and help maintain the tree species diversity. CCI suggests thinning intensities of 18.3% and 18.4% for the first and second sample plots, respectively. Presented methods and results may provide auxiliary supports for scientific thinning and help promote the application of information technology in forest management.


The present study was undertaken to assess the potential of Borassus flabellifer mucilage (BFM) to act as a biodegradable carrier for colon specific drug delivery. Hence an attempt was made to develop matrix tablet of olsalazine sodium based formulation using BFM which protects the drug in upper GIT and release the major amount of drug in colon due to degradation by bacterial enzymes. Colon targeted matrix tablets of olsalazine sodium were prepared by direct compression method using different concentrations viz; 5, 10, 15, 20 and 25% w/w of BFM. Tablets were evaluated for hardness, friability, weight variation, drug content, in vitro dissolution test in simulated gastric, intestinal and colonic fluid with and without 4% (w/v) rat caecal matter and stability study. FT-IR and DSC studies confirmed the absence of any drug polymer interaction. In vitro studies revealed that the tablets containing 25%w/w of BFM (F5) have limited the drug release in stomach and small intestinal environment and released maximum amount of drug in the colonic environment. Optimized formulation (F5) showed no change either in physical appearance, drug content or in dissolution pattern after storage at 400C/RH75% for 3months. Mathematical modeling showed that release pattern follows the Peppas model. X-ray images were taken to investigate the movement, location and the integrity of the tablets in different parts of gastro intestinal tract in rabbits and it clearly supported the in vitro study. The study showed that BFM can be used successfully for colon specific drug delivery system.


We study the asymptotic winding angle distribution of a two-dimensional Brownian curve around a given point. The influence of boundaries and/or drifts on this distribution is addressed. In particular, we show that, for some special drifts, the limiting distribution is given in terms of Levy laws.


In the frame of detail mapping of parametamorphic rocks on the southeastern slopes of Mt. Medvednica (Zagorje-Mid-Transdanubian zone, Croatia), samples of the chloritoid schists from the upper part of geological column were analyzed in more detail. This study is a part of preliminary research that included XRD, XRF, ICP-MS, SEM, electron microprobe and microstructural characterization of chloritoid schists in order to determine their petrography, microstructural features, mineral assemblages, phase composition, whole-rock and mineral chemical composition and morphology of accessory minerals (zircon typology). The samples can be categorized as chlorite-muscovite-quartz schist, chloritoid-chlorite-quartz-muscovite schist, chlorite-muscovite-quartz-chloritoid schist and interbeds of marble. Accessory minerals in chloritoid schist are tourmaline, zircon and rutile. Microstructural features show two deformational events, the sinmetamorphic and postmetamorphic events. The latter deformational event is recorded in the development of flazer structure, where the mineral grains in cleavages are translated, fractured and rotated. The whole-rock chemical analyses show high concentrations of SiO2 (74.79 wt. %), K2O (2.5 wt. %), Al2O3 (13.22 wt. %), and low values of MgO (0.99 wt. %) and CaO (0.08 wt. %).These results indicate that acid rocks could be a possible protolith. The REE distribution normalized to chondrite shows higher LREE to HREE concentrations ((La/Yb)N=5.68, (La/Sm)N=3.05, (Gd/Yb)N=1.21), while the Eu anomaly has a low value (Eu/Eu*=0.7). Such metamorphic mineral assemblage is characteristic for low-grade metamorphism. The chlorite-chloritoid geothermometer gives metamorphic temperature values of approximately 450°C. The source rocks of the chloritoid schist are argillaceous sandstones, derived from acid magmatic rocks, interbeded with carbonates. Carbonate interbeds indicate deposition in a marine environment. The morphology of zircons shows that the source for protolith is of granitoid composition, while their weak roundness indicates a short transport.


Background: Mount Merapi Eruption 2010 in Sleman affected psychological trauma that can appear more than 10 years. The population that susceptible to this impact is preschool children. Symptom that appear on preschool children is decrease their independent level. Children more dependent to the caregiver. This conditions need to manage in order that there is no interfere on child development. One of the effort to increased independent level of child is local cultural wisdom games.
Objective: The study aimed to identify influence games based on local cultural wisdom to independet level of kindergarten student at dwelling in Cangkringan Sleman.
Method: The study was quasi experimental with pre-test and post-test control group design. The study carried out on February-April 2014. Sample was children age 4-6 years old from 2 kindegarten near the dwelling that consist of 49 children intervention group and 49 children control group. Data of this study analized with parametric t-test.
Result: There was significant difference between intervention group and control group. Before intervention of local cultural wisdom games, child independent score in intervention group was 81,79±8,43 and control group was 82,36±7,94. After intervention, child independent score in intervention group was 85,89±8,13 (p=0,001) and control group was 82,71±6,99 (p=0,410).
Conclusion: There was influence of gemes based on local cultural wisdom to independent level of kindergarten student at dwelling in Cangkringan Sleman.


With the development of the Internet of Things, new devices need more diversified input methods. Gesture recognition has become a hot research field, and air-writing [1] is a significant part of the field of gesture recognition. In our previous air writing recognition system, we proposed an input system that measures dynamic data based on an inertial measurement unit that uses a dynamic time warping (DTW) algorithm for recognition. In this paper, cDTWw algorithm, KNN & DTW classification algorithm and fastDTW algorithm are used for comparative experiments. In order to improve the actual recognition ability of the air writing system, save the recognition time as much as possible , and optimize the recognition accuracy. We found that the cDTW w algorithm has a faster recognition speed than the fastdtw algorithm in the air writing recognition system. KNN & DTW class fication algorithm significantly improves the recognition accuracy in the air writing recognition system.


That the other cases had been of a similar eheaWactew seemed to me almost certain, from the perfeet; simiity df bthe symptoms they had presented. The i~w iab1e qularrel which had preceded them favours this view, such occurrences being common attendants on and consequences of a drinking bout amongt low persons. The peculiarity of the phenomena is probably to be explained by the age of the patients and their social relations. It is not probable that they would be allowed to sit and drink with their seniors or masters, and their potations would probably be stealthy, and a consequence of the stealthiness would be that whatever liquor they took would be swallowed hastily, as it were en masse, not sipped. There can be no doubt that this makes a great difference in the effect of intoxicating liquors. The cases that we see reported of fatal alcoholic poisoning are almost invariably those of persons who for some foolish freak, wager, or "bravado, have drunk off at once large doses of spiits, quantities which probably would have been comparatively harmless, at least not fatal, had they been taken in a less brutish and irrational manner; the symptoms of such cases differ from those I have deocribed rather in degree than in kind. It is also possible that the mere age of the patient may have something to do with the peculiar phenoma. I have certainly noticed that the narcotic effeets ofalcohol are more readily, or at all events more quently, developed in young persons than in their elders. The explanation of this fact, if it be a fact, is not very patent. Whether it depends upon the greater rapidity of ingestion, or on the local action upon the somach and its nerves being greater, or upon a more facile absorption, I cannot tell.* So much for these cases themselves. If it be true that tiey are intrinsically of but limited interest, stil they suggest, not very directly perhaps, other considerations of the highest and most practical importance. We all know that of late years the practice of administering laxge doses of alcohol in acute disease ha been revived. The beneficial effects which sometimes attend this practice are explained by some upon the supposition that alcohol supplies the place of tbod, by others on the theory that it stimulates the nervous system. Each class rely much upon the absene of alcoholic odour in the breath, or perspiration, as showing that the alcohol is all consumed in the system, and can exercise no pernicious influences. .And yet it is to be observed that there was no alcoholio odour in the breath, or perspiration, of these patients, who were as it seems to me suffering from distinwt, though not severe, alcoholic poisoning. The further remarks that I have to offer are intended for the consideration of those who base their therapeutial se of alcohol upon the stimulant theory. Supposing as I do that our conception of the idea of a stimulant is mainly derived from observation of the effects of certain doses of alcohol upon certain persons, I am not about to deny that these effects masy be producible in disease; nor am I at all prepared to dispute that these stimulant effects are, or ma,y be to some extent beneficial; but on the other hand, I venture to suggest that when we prescribe alcohol we should not, as has hitherto been done, absolutely ignore the unquiestioned and unquestionable fwht that it does possess narcotic powers.


[1] The magnetosheath is characterized by a variety of low-frequency fluctuations, but their features and sources are different. Taking advantage of multipoint magnetic field measurements of the Cluster spacecraft, we present a statistical study to reveal properties of waves. We compute cross-correlation coefficients of magnetic field strengths as measured by pairs of the Cluster spacecraft and determine the correlation length of magnetosheath waves. We discuss the relationship between the correlation length and upstream parameters as well as its connection with the wave mode and frequency power spectrum. In the frequency interval of 0.001–0.125 Hz, we found that the correlation length of fluctuations increases (1) through intervals of high solar wind speeds, (2) with increasing interplanetary magnetic field (IMF) strength, (3) if the cross-correlation between the IMF and magnetosheath magnetic field is higher, and (4) if the amplitude of fluctuations is larger.


Aluminium thin film is widely used for high reflectivity reflector. However, it is readily corroded in a variety of environments and in oxygen saturated water. Coatings deposition on it is considered as a way of increasing its corrosion resistance. Among all available deposition techniques, the use of plasma-assisted technologies has grown rapidly. Organosilicon monomers have been successfully used as precursors of Si-based films and among them hexamethyldisiloxane (HMDSO) has gained increasing interest owing to its lower cost and higher deposition rates comparing to similar silicon containing monomers. This work studies the effects of depositing parameters on the structure and composition of the coating and at last on the corrosion protection performance concerning their use as protective coatings on reflective aluminum metallisations. Therefore, we have done a serial of experiments and got corresponding samples with different parameters such as HMDSO glow discharge power and depositing time. In the experiments, the plasma polymerized HMDSO thin films have been obtained in a DC glow discharge from the monomer vapor. And then the corrosion protection performances are analyzed by environment experiments. To analyze the reason of the deposition parameters effect on protection performances, the chemical structure and composition of the films have been analyzed.


Graphene is a sp2-hybridized carbon sheet with an atomic-level thickness and a wide range of graphene applications has been intensely investigated due to its unique electrical, optical, and mechanical properties. In particular, hybrid graphene structures combined with various nanomaterials have been studied in energyand sensor-based applications due to the high conductivity, large surface area and enhanced reactivity of the nanostructures. Conventional metal-catalytic growth method, however, makes useful applications difficult since a transfer process, used to separate graphene from the metal substrate, should be required. Recently several papers have been published on direct graphene growth on the two dimensional planar substrates, but it is necessary to explore a direct growth of hierarchical nanostructures for the future graphene applications. In this study, uniform graphene layers were successfully synthesized on highly dense dielectric nanowires (NWs) without any external catalysts. We also demonstrated that the graphene morphology on NWs can be controlled by the growth parameters, such as temperature or partial pressure in chemical vapor deposition (CVD) system. This direct growth method can be readily applied to the fabrication of nanoscale graphene electrode with designed structures because a wide range of nanostructured template is available. In addition, we believe that the direct growth growth approach and morphological control of graphene are promising for the advanced graphene applications such as super capacitors or bio-sensors.


A new interest in intertemporal choice is fueled by evidence of non-constant time discounting and a much better understanding of its theoretical consequences. This paper reports the results of a …eld experiment in rural Malawi designed to evaluate, directly, the relationship between intertemporal choice under commitment and time-inconsistency. The experiment used real choices over money to elicit time preferences from approximately 2,200 subjects. The stakes of the intertemporal choices were high, representing a total of about one month's wages, on average. A randomly selected subset of respondents was later approached in the two weeks prior to their …rst disbursement of money. These subjects were reminded of their initial choices and asked if they would like to revise them and thus exhibit time-inconsistency. Choices under commitment reveal important heterogeneity in basic consistency of choice, time preference, and dynamic consistency. When the commitment is broken, revisions are common, and they are only somewhat more likely to reallocate income backward in time. Following the theory, revisions are strongly associated with preferences under commitment. Niall Keleher, of Innovations for Poverty Action, was instrumental to the design and implementation of this study. We thank him for his important contributions to this project. We also thank James Andreoni, Stefano DellaVigna, Yoram Halevy, Glenn Harrison, Pam Jakiela, Damon Jones, David I. Levine, Stephan Meier, Ted Miguel, Matthew Rabin, and participants in several seminars for their many helpful comments. yGiné: Development Economics Research Group, World Bank (firstname.lastname@example.com); Goldberg: Ford School and Department of Economics, University of Michigan (email@example.com); Silverman: Department of Economics, University of Michigan and NBER (firstname.lastname@example.com); Yang: Ford School and Department of Economics, University of Michigan and NBER (firstname.lastname@example.com).


Successful relationships involve a significant amount of give and take. A problem arises when one partner starts to believe that he is doing more than receiving in return. Rather than bring it up directly into the open where it can be dealt with, couples usually allow their feelings to smolder until frustration builds into resentment. At that point, partners become critical and accusatory or shut down and then pull away from their mate.


This paper analyzed the lesson of manage of plantation forest nearly decade in Heilongjiang province,summarized the experiences about manage the plantation.We must do some working from five aspects: protects of originality of natural forest,cleaning of cutting natural forest,natural reproduction of plantations,protection of biodiversity,protection of natural female forest and elite breed base building,in order to achieve nature and concordant of natural manage of forest.


This  study  aims  to  examine  the  effect  of  greed,  opportunity  on fraud Procurement of  Government Goods   /   Services with moderated leadership ideals. This type of research is quantitative research, using a questionnaire as a research instrument.
The method of analysis in this study used the Partial  Least  Squares  Structural  Equation  Modeling  (PLS  SEM) .
The  results  showed  that  greed, opportunity has  positive  effect  on fraud Procurement of Government Goods / Services. These results show that the higher the greed in individuals, the higher the potential to commit fraudulent acts of procurement of goods/services.   The higher the opportunity to commit fraud, the higher the potential for someone to commit fraud. Moderate variable analysis shows that the idealism of the leader is able to moderate the greed and opportunity.


&NA; A 72-year-old man who had received four cycles of the anti-cytotoxic T-lymphocyte antigen-4 (CTLA-4) ipilimumab1 for advanced metastatic melanoma, presented with a rapid deterioration in mental state, deranged serum electrolytes, abnormal thyroid function and evidence of diabetes insipidus. Serum biochemistry and brain imaging raised the possibility of immune-mediated hypopituitarism related to ipilimumab. After failure to respond to therapy, active treatment was withdrawn. Methods: The post-mortem findings are reported, with emphasis on the pituitary histopathology, including immunohistochemical elucidation of the inflammatory infiltrate. Results: Near total loss of anterior pituitary endocrine tissue and patchy chronic inflammatory involvement of the neurohypophysis, consistent with infundibulo-panhypophysitis.2,3 Notably there was no residual melanoma identified in the sites suspicious on pretreatment imaging of metastases. Discussion: Auto-immune hypophysitis is a rare immune-mediated adverse event associated with administration of ipilimumab2,4–6 used in the treatment of advanced melanoma.7–9 Trials suggest that autoimmune hypophysitis may occur in up to 17% of treated patients.2 Generally, patients are diagnosed on imaging and show a clinical-radiological response to steroids and hormone replacement therapy, and biopsy is not performed.2,4,8,9 This case offers a rare opportunity to examine the histology of infundibulopanhypophysitis after treatment with the anti-CTLA-4 antibody ipilimumab. ReferencesFong L, Small EJ. Anti-cytotoxic T-lymphocyte antigen-4 antibody: the first in an emerging class of immunomodulatory antibodies for cancer treatment. J Clin Oncol 2008; 26: 5275–83.Dillard T,Yedinak CG, Alumkal J, et al. Anti-CTLA-4 antibody therapy associated autoimmune hypophysitis: serious immune related adverse events across a spectrum of cancer subtypes. Pituitary 2010; 13; 29–38.Caturegli P, Newschaffer C, Olivi A, et al. Autoimmune hypophysitis. Endocr Rev 2005; 26: 599–614.Gutenberg A, Landek-Salgado M, Tzou SC, et al. Autoimmune hypophysitis: expanding the differential diagnosis to CTLA-4 blockade. Expert Rev Endocrinol Metab 2009; 4: 681–98.Ribas A, Camacho LH, Lopez-Berestein G, et al. Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206. J Clin Oncol 2005; 23: 8968–77.Attia P, Phan GQ, Maker AV, et al. Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4. J Clin Oncol 2005; 23: 6043–53.Weber J. Ipilimumab: controversies in its development, utility and autoimmune adverse events. Cancer Immunol Immunother 2009; 58: 823–30.Barnard ZR, Walcott BP, Kahle KT, et al. Hyponatremia associated with Ipilimumab-induced hypophysitis. Med Oncol 2012; 29: 374–77.Carpenter KJ, Murtagh RD, Lilienfeld H, et al. Ipilimumab-induced hypophyositis: MR imaging findings. Am J Neuroradiol 2009; 30: 1751–3.