A compound of formula (I): (See formula) where each of x and y is, independently of the other, 0 or 1; R1 is substituted or unsubstituted aryl or heteroaryl, especially phenyl, which is substituted with up to 4 substituents, preferably up to 3 substituents, wherein the substituents are the same or different and are independently selected from halo, for example, F or CI; lower alkyl which can be unsubstituted or substituted with halo, especially methyl, ethyl, propyl or trifluoromethyl; cyano; cyano-lower alkyl, for example, cyanomethyl, cyanoethyl or cyanopropyl; lower alkoxy; Not me; amino-lower alkyl; lower amino alkoxy; amino-lower alkyl sulfanyl; or thiol-lower alkyl, wherein the amino group may be mono- or di-substituted, for example, - (C1-C7) mNR8R9 or -O- (C1-C7) mNR8R9, where m is 0 or 1; and R8 and R9 can be the same or different and are independently H; lower alkyl, for example, methyl, ethyl or propyl; Lower cycloalkyl, for example, cyclopropyl, or R8 and R9, together with the N atom, form a 3- to 8-membered heterocyclic ring containing 1-4 nitrogen, oxygen or sulfur atoms, for example, azetidinyl, pyrrolidinyl , piperidino, morpholinyl, imidazolinyl, imidazolinyl ethyl, piperazinyl or lower alkyl-piperazinyl; amino-carbonyl-lower alkyl, for example, R8R9-N-C (O) -CH2-, wherein R8 and R9 are as defined above; heterocyclyl; heterocyclyl-lower alkyl; heterocyclyl-lower alkoxy; or lower heterocyclyl-alkanesulfanyl, wherein the heterocyclyl is a 3- to 8-membered heterocyclic ring containing 1-4 nitrogen, oxygen or sulfur atoms, for example, imidazolyl, imidazolinyl, pyrrolidinyl, morpholinyl, azetidinyl, pyridyl, piperidino , piperidyl, piperazinyl or lower alkyl-piperazinyl; substituted or unsubstituted amide; amide-lower alkyl, for example, -CH2-CH (NH2) -C (O) -NH2), wherein alkyl can be linear or cyclic, for example, cyclopropylene; and the alkyl in any of the above substituents may optionally be substituted with -NR8R9, wherein R8 and R9 are as defined above; X is C = O or C = S, with the condition that then the dotted line joins X to N is absent, so that X is attached to the adjacent N via a single link and with the condition that then y is 1 and R is hydrogen or an organic functional group that may be attached to nitrogen, or X is (CR7), wherein R7 is hydrogen or an organic functional group, such as lower C1-C7 alkyl; Not me; or amino alkyl, wherein the alkyl can be unsubstituted or substituted with halo, for example, methyl, ethyl, propyl or trifluoromethyl; lower alkoxy, for example; methoxy; or cycloalkyl, for example, cyclopropyl; with the condition that the dotted line then joins X to N is a link, so that X is attached to the adjacent N via a double bond; and with the condition that then y is zero, or y is 1 and then -R is -> O; R2 is hydrogen; R3 is ...


Consumers in e-commerce acquire information through search engines, yet to date there has been little empirical study on how users interact with the results produced by search engines. This is analogous to, but different from, the ever-expanding research on clickstreams, where users interact with static web pages. We propose a new network approach to analyzing search engine server log data. We call this searchstream data. We create graph representations based on the web pages that users traverse as they explore the search results that their use of search engines generates. We then analyze the graph-level properties of these search network graphs by conducting cluster analysis. We report preliminary evidence the presence of heterogeneity among users in terms of how they interact with search engines. This suggests that search engine users may not all benefit from the same functionality in the search engines they rely upon. We also offer additional evidence on the empirical regularities associated with a variety of relevant issues that arise in the business-to-business (B2B) e-market context that we have studied.


The invention relates the cell checkout sensing device, comprising small mobile chamber 1, big mobile chamber 2, input connection 11, capillary 5 and 10, and outlet connection 9. The left end of small mobile chamber 1 is connected with the right end of big mobile chamber 2, between them there is hole 8, left end cover 3 is connected with big mobile chamber 2, on the front of left end cover 3 there is sample connector 4 and capillary 5, input connection 11 is connected with left end cover 3, on the right end of small mobile chamber 1 there is outlet connection 9, in the outlet connection 9 there is capillary 10, sample connector 4 is connected with sample tube, the input connection 11 is connected with sheath tube, and the outlet connection 9 is connected with negative pressure chamber. The invention improves the accuracy and reducing the cost.


The stabs on a busbar for mechanically and electrically receiving circuit breakers, or the like, are shaped so as to have two mutually perpendicular contact plug-in elements on a single stab enabling the single stab to receive circuit breaker contacts that are oriented in mutually perpendicular directions.


My invention relates to the manufacture of fertilizer in which refuse or waste mate rials from packing-house, fisheries or other industries, which are hereinafter termed am moniates, are employed as a source of nitro gen and ammonia. The object of my invention. is two-fold first, to utilize as an ammoniate, pigly refuse or waste material of t le packing house, and fisheries industries, (particu larly tankage, fish-scrap, or fish chun, blood etc.) in the crude state, as it comes from the press and with its contained moisture (40 to 50% by weight), and convert it into good o merchantable condition with out the application of artificial heat, or other Fis drying process, which tends to drive off the effective fertilizing principle, whereby I am enabled to effect both a large saving in ammonia, with corresponding increase in market value of the material, and a reduc tion in the cost of production; second, to combine with said ammotiates substances having the intrinsic qualities not only of add


The pollen morphology and stem anatomy of four Salsola species (Chenopodiaceae) includes S. crassa Bieb., S. jordanicola Eig., S. longifolia Forsk. and S. vermiculata L. from the southern Iraq were studied. The results of the present study demonstrated that the pollen grains of the four species were characterized by isopolate, spheroidal, polyporate, circular pore and nanospinulate ornamentation. The pollen diameter, pore number, pore diameter, average of the distance between the center of the pores and C/D ratio that can play an important role in species separation. Pollen diameter and pores number have been shown to give a good taxonomic significance to divide the species in tow groups. S. crassa have been largest pollen grains and pore numbers than with other three species that had been studied. The results of the stem anatomical features investigation provide really significant taxonomical value to distinguish the Salsola species, thickness of the epidermis, Cuticles, Chlorenchyma Collenchyma, Sclerenchyma and also Xylem row length were important to separate the four species. Pith diameter to stem diameter percentage (P/S) were varied among four Salsola species and showed a taxonomical value among the


It's a kinds of response for a client inquire from the manufacturing enterprise which comprise the objective products' price etc. To refer the client an well-pleasing quotation, to neaten, and to print it fastly, many quoted pricing system were developed in allusion to diversified products. This paper continues to discuss it with the prefab cold storage quoted-pricing system.


The rare-earth oxides M2O3 (M=La, Pr, Gd) are good insulators due to their large band gap (3.9eV for Pr2O3, 5.6eV for Gd2O3), they have high dielectric constants (Gd2O3 K=16, La2O3 K=27, Pr2O3 K=26-30) and, compared to ZrO2 and HfO2, they have higher thermodynamic stability on silicon making them very attractive materials for high-K dielectric applications. Another attractive feature of some rare-earth oxides is their relatively close lattice match to that of silicon, offering the possibility of epitaxial growth and eliminating problems related to grain boundaries in polycrystalline films. Metal-organic chemical vapor deposition (MOCVD) has been preferred to PVD methods because of the possibility of large area deposition, good composition control and excellent conformal step coverage. Herein we report on the synthesis of rare-earth oxide complexes with designed alkoxide and aminoalkoxide ligand. These novel complexes have been characterized by means of FT-IR, elemental analysis, and thermogravimetric analysis (TGA).


Experiments were conducted to examine the dynamics of the sediment‐associated polychlorinated biphenyl (PCB) Aroclor® 1254 using a benthic‐based trophic transfer model (sediments to benthic copepods to juvenile fish). Field‐collected benthic copepods were exposed to sublethal levels of Aroclor 1254 in sediments for 96 h. Accumulation of PCB was measured in the copepods, and these contaminated copepods were fed to the juvenile fish predator Leiostomus xanthurus in uncontaminated sediments. After gut clearance, whole fish were homogenized and examined for PCB accumulation. Similar experiments with L. xanthurus in which meals of uncontaminated copepods were fed in PCB‐contaminated sediments were conducted to determine the relative roles of contaminated sediments and contaminated copepod prey ingestion to PCB transfer. Total PCB transfer as well as PCB congener group contributions were examined. A total of 30 congeners were grouped according to log Kow increments and according to chlorine homologue groups. Copepods exposed to PCB‐contaminated sediments to 90 μg/g accumulated PCBs to 326 μg/g dry weight. Accumulation of PCB in fish feeding in contaminated sediments was five times higher than that in fish feeding on contaminated prey in uncontaminated sediments (p = 0.0498). In terms of congener patterns, log Kow grouping provided clearer discrimination between groups. Congener patterns were similar in PCB stock solution, sediments, and copepods and were different in the two fish treatments. Kow group relative accumulation patterns in fish were mixed. The chlorine homologue groups revealed that the fish preferentially accumulated the tetrachlorinated congeners relative to copepods and sediments.


The coronavirus disease (COVID-19) pandemic has changed the education system, including problem-based learning (PBL), which is the main curriculum model in medical education. Social interaction and acquisition of knowledge and skills are one of the challenges in online learning during a pandemic. This study evaluated the use of the flipped classroom in the PBL curriculum of medical education. This study used mixed-methods design with a concurrent approach. The data collection technique was secondary data collection in the form of data from the block learning evaluation form. The evaluation form contains statements regarding the quality of the learning process, in the form of Likert scales. At the end of the form, there was a fill-in/essay question for more in-depth exploration. The quantitative data were analysed using descriptive univariate analysis, meanwhile, the qualitative data were analysed using thematic analysis techniques. Unbalanced learning load on the block, block learning management, and knowledge retention in block learning were considered lacking in flipped classroom block implementation. The management of time delays, a stage for students to be ready, a step to lessen psychological stress, and the use of media to generate different learning experiences are particular areas that need improvement.


In many colonized and formerly colonized countries, modernity and colonialism have been introduced as two sides of the same coin. Engaging the discourse of colonial modernity and introducing the concept of ''Protestant modernity,'' Choi shows how in colonial Korea under Japanese rule gender relations were challenged and deconstructed/reconstructed under the powerful influences of Christianity. She carefully articulates ''the concept of Protestant modernity as a heuristic device'' for understanding the complicated dynamics of gender relations and its interactions with global Christianity and defines it as ''a composite of religious morality, historical outlook, and material practices that could mean different things to different historical subjects'' (15). Recognizing the dynamics between Japanese colonial imperatives, Korean nationalism, Western modernity, and global evangelical Christian ambition, she analyzes how transnational dynamics and flows between transferring knowledge and the mobility of people through Christian networks influence gender norms and culture. Concentrating on the period from the late nineteenth century to the early twentieth century (up to around the 1930s), she demonstrates how Korean elite women as the subject—not the colonial object—understood transnational encounters and used Christian networks to develop their own ways of building modern, cosmopolitan, and national identities to participate in the restoration of the Korean nation. In chapter 1, Choi shows how the ideology of ''wise mother, good wife'' played out in different cultural contexts and contributed to forming gender ideology in Korea. As she examines Japanese colonial gender ideology from


This study is an examination of the effect of interorganizational dependencies on compliance with government affirmative action demands. Defense contractors were the subjects in the study. The spee...


The purpose of this study was to find paint remover for defective coating of inotocycle oil tank. Base components as well as the action - mechanism of paint remover were prelidrinery investigated. in addition, the application and operating hints were described by examples.


In practical orthogonal frequency division multiplexing (OFDM) systems, some virtual subcarriers are reserved for easing the requirements on the filter. In this case, the conventional discrete Fourier transform (DFT)-based filtering in frequency-domain suffers from a spectral leakage, which results in an irreducible error floor. On the other hand, the DFT-based filtering or interpolation in time-domain also has performance degradation for system with high Doppler frequency. In order to solve these two problems, we propose a two dimensional discrete cosine transform (2D DCT)-based channel estimator for OFDM systems with virtual subcarriers and high Doppler frequency. Simulation results show that the performance of the proposed method can well approach the 2D minimum mean square error (MMSE) channel estimation.


OBJECTIVE To investigate whether C.elegans may represent a suitable model for rapid preliminary acute toxicity studies of pharmaceutical compounds.METHODS Sensitivity of the wild-type C.elegans strain N2 and mutant-type strain glp-4;sek-1 in the presence of the same drugs was determined by lethality.The half lethal concentration(LC50)(72 h) of four types of antibiotics and 3 anti-tumor drugs was measured.RESULTS LC50 of erythromycin on N2 strain and glp-4;sek-1 strain was 250 and 120 mg·L-1.LC50 of azithromycin on N2 strain and glp-4;sek-1 strain was 411 and 286 mg·L-1.glp-4;sek-1 Strain was more sensitive than N2 strain,so glp-4;sek-1 strain was used as model system for toxicity assessment of drugs.LC50(72 h) was 100-300 mg·L-1 for macrolides,300-400 mg·L-1 for tetracycline,400-2500 mg·L-1 for aminoglycosides and 40-60 mg·L-1 for anti-tumor drugs.Compared with mice,C.elegans was susceptible to the toxicity of drugs.Also,toxicity of most tested drugs presented in C.elegans system was similar to that of the mouse system,indicating that the two evaluating systems had a good positive correlation.CONCLUSION C.elegans is a suitable model system to determine the toxicity of drugs.This approach allows for an easy and fast ranking of compound toxicity,which may facilitate a more rational choice for further in vivo tests.


Over the past few decades the authors have visited a number of developing countries in Africa, Asia and the Americas, providing both general ophthalmology care and specialised consultation, teaching and service. The programmes initially were largely oriented towards cataract surgery and glaucoma care in more rural areas, then towards teaching in the field of paediatric ophthalmology and strabismus in large city hospitals. There seems to be a never-ending amount of service needed in these countries, although, over time, the ability of colleagues to provide service to their own people has increased. However, as the cataract backlog is reduced, there develops an interest in learning specialised ophthalmic concepts and surgery techniques.

Volunteers visiting a developing country should not make assumptions based on previous visits because perceptions and conditions in the country vary. It is essential to have good communications with colleagues in the country visited.

The recognition and application of three major principles should be observed on medical mission trips:

Appropriate technology based on the existing infrastructure and the needs determined at both local and national level.

'Empowerment' of the physicians and paramedical personnel in the country. This should include informal teaching in the clinic, working together with colleagues in the operating room, as well as formal lectures and courses at centres of medical education.

Project sustainability. Equipment should be donated to local organisations, such as Lions Clubs or Rotary Clubs with support organisations placed in those Clubs so that return trips can be organised more effectively. There is a need, also, for colleagues in these countries to come for further training in more developed countries. This provides the greatest amount of 'multiplier effect', as then a person can return to his or her own country and devote his or her career to service in ophthalmology – particularly paediatric ophthalmology and strabismus, the specialty interest of the authors.

Appropriate Technology
Supporting the improvement in technology in a developing country should be 'step by step', rather than by introducing the latest technology, which may remain unused. For example, phakoemulsifiers at small hospitals in the poorly served periphery (e.g., rural areas) may be used by the visiting specialist, after which it may be placed under a dust cover for years. In countries where the water supply is not clean, sediment in the water supply typically contaminates the lenses of lasers, reducing effectiveness and ultimately the use of the laser. It is best to work with colleagues in these countries to select what is appropriate. Surgical instruments are most commonly needed.


There are at least two races of spotted dolphin, Stenella attenuata, in the eastern Pacific, based on length, color pattern, and skeletal differences. The coastal form is provisionally called S. attenuata graffmani. The offshore form is distinct from a third, Hawaiian race. Likewise, at least three unnamed races of spinner dolphin, S. longirostris, occur in the eastern Pacific. Length, shape of adult male, color pattern, and cranial differences are used to distinguish a Costa Rican, an eastern, and a whitebelly race. An Hawaiian race is distinct from these. A distributional break may indicate two stocks of the striped dolphin, S. coeruleoalba.


To study the surface hydrophobicity of solid materials with the lattice Boltzmann method, a rough surface is approximately treated as simple periodic rectangular, saw-tooth and semicircular protrusion structures separately. A two-phase lattice Boltzmann model is used to simulate the change of surface hydrophobicity by calculating the contact angle of a droplet on the rough surface. Finally, the fluid flow in a nano-channel with rough walls is studied.


Objective:To explore the infection status of adult Metorchis orientalis in the definitive host,the domesticated ducks,in Huainan area.Methods:Sixty female domestic ducks,aged 18 month and weighing(2.5±0.5)kg,were purchased from the fishermen living in the water areas of Yaohe and Gaotanghu in Huainan District,and all animals were killed to obtain the adult worms from the hepatobiliary system,with calculation of infection rate.Results:Adults of Metorchis orientalis were found in the hepatobiliary systems in domesticated ducks in Huainan area,and the infection rate of this parasite was 18.3%(11/60).Conclusion:Metorchis orientalis has been detected in the hepatobiliary systems in ducks natively raised in Huainan Area.


Abstract Icing scaling tests were performed in the NASA Glenn Icing Research Tunnel to evaluate a new scaling method (Ref. 1), developed and proposed by Feo for glaze icing, in which the scale liquid water content and velocity were found by matching reference and scale values of the nondimensional water-film thickness expression and the film Weber number. For comparison purpose, tests were also conducted using the constant We L method for velocity scaling. The reference tests used a full-span, fiberglass, 91.4-cm-chord NACA 0012 model with velocities of 76 and 100 knot and MVD sizes of 150 and 195 m. Scale-to-reference model size ratio was 1:2.6. All tests were made at 0° AOA. Results will be presented for stagnation point freezing fractions of 0.3 and 0.5. Introduction The ability to conduct icing tests with subscale aircraft components in an icing wind tunnel depends critically on our understanding of physical mechanisms that affect the ice accretion process and our ability to measure and control test conditions in an icing tunnel. The need to develop appropriate scaling methods has been long recognized, and research efforts have begun as early as in the 1950s and continue to the present. Recently, Anderson (Ref. 2) and Anderson and Tsao (Ref. 3) have completed two NASA reports that provide a detailed technical review of recommended scaling methods for ice accretion on unprotected, unswept aerodynamic surfaces in Appendix C and super-cooled large droplets (i.e., SLD) conditions, respectively. It was concluded from those two references that acceptable scaling results could be achieved by matching the 


One-dimensional (1D) cadmium sulfide nanorods were successfully synthesised using cadmium nitrate and sulfur powder as starting materials and polyvinyl alcohol (PVA, MW = 1 25,000) as a capping agent in ethylenediamine as a solvent by solvothermal method at 200°C for 24 and 72 h. X-ray diffraction patterns (XRD) indicated a single phase of hexagonal wurtzite CdS structure, of which the results are in accordance with those of selected area electron diffraction (SAED). The morphologies of CdS were observed using scanning electron microscopy (SEM) and transmission electron microscopy (TEM) which showed 1D nanorods. The length and diameter of CdS nanorods were increased when PVA was added and the reaction times were prolonged. High resolution transmission electron microscopy (HRTEM) showed that growth direction of wurtzite CdS nanorods is along [001] direction or c-axis. Raman spectra presented the 1LO and 2LO at 299.36 and 600.72 cm−1, respectively. The 2LO/1LO intensity ratios were increased when the length of CdS nanorods became longer.


This research aims at investigating how well EFL university students in the Department of English Colleges of Basic Education/ University of Mosul master the patterns of the English sentence. It hypothesizes that students of EFL do not have the level of proficiency of English Grammar that enables them to recognize different patterns and elements of sentences. The research also hypothesizes that there are some of the sentence patterns that are more easily recognized by EFL students than others.             With (50) participants, the instrument used for testing these hypotheses is a questionnaire designed by the researcher. This questionnaire is used to measure students' knowledge and command of the seven patterns of the English sentence. Using the software package SPSS, the data is analyzed. The results show that participants are still unable to learn and develop their recognition of correct sentence elements and patterns. Moreover, some patterns have been mastered by EFL learners better than others.


The construction sector exerts detrimental environmental impacts on natural ecosystems. Mitigating these impacts and reducing pollution necessitates the adoption of an assessment tool. During the design phase, decisions must factor in building typology, materials, construction techniques, dimensions, functions, and contextual considerations. Crafting solutions that effectively address all these facets presents a formidable challenge. The European Union (EU) advocates for employing the Life Cycle Assessment (LCA) methodology to evaluate environmental impacts in the construction industry. This approach encompasses the entire lifecycle of a product, encompassing production, usage, and disposal stages. However, integrating additional elements such as the urban context and digital twin technologies remains intricate. Given the impending need to enhance energy efficiency in the European building stock through extensive redevelopment, this research aims to identify a robust methodology for selecting optimal building materials. This review seeks to offer an updated perspective encompassing the choice of eco-friendly building materials and the incorporation of digital twin technologies, which facilitate real-time building assessments. By amalgamating insights derived from this analysis, this research strives to contribute to a holistic framework that addresses the multifaceted aspects of sustainable construction. Such a framework would streamline the selection of environmentally conscious building materials while harnessing the potential of digital twin methodologies for rapid and precise building evaluations. Ultimately, this research aspires to bridge critical gaps in sustainable practices within the construction sector, aligning with the EU's overarching objectives of promoting greener and more efficient built environments.


We report velocity-resolved spectroscopy of infrared hydrogen recombination lines in the interacting region of the Antennae galaxies (NGC 4038/4039). It generally has been assumed that the active star formation found there is due to the interaction of the disks of the two galaxies and indeed two molecular cloud complexes, separated in velocity by ~100 km s-1, have been observed in the southern part of this region. Our measurements imply that the two cloud complexes are moving away from each other. This result poses interesting questions about the physical mechanisms leading to starbursts in Arp 244 and other interacting galaxies.


Crafts and industries were a main feature of the economic life of the people of Paralakhemundi Zamindari since very early times. Although agriculture formed the main feature of the economic life of the people, yet there existed several crafts and industries in Paralakhemundi and it's surrounding areas during the rule of Sri Krushna Chandra Gajapati, the king of Paralakhemundi. A considerable portion of population of this region earned their livelihood working as manufacturers of various agricultural and non-agricultural products.


As one of the difficulties and hot of computer vision and image processing, Image segmentation is highly valued by the research workers. Yet there is no image segmentation algorithm which is generic, and it is difficult to obtain an optimal feature representation method. In this paper, particle swarm optimization has proposed to segment the image. PSO algorithm can improve the efficiency and quality of the picture some extent through the experimental results. The algorithm has some versatility, as long as the corresponding parameters are adjusted, it can also handle the other images. The results show that PSO algorithm is very stable, and the fusion result is more satisfactory.


We herein describe a case of 45-year-old female, who presented with multiple non-healing ulcers over both shins from past 2 years. She was being treated for vasculitis from some private institution till date. After proper history given by the attendant she was found to be using pentazocine injections for multiple somatic complaints. With subsequent psychiatric counseling, the lesions healed after 3 months of treatment.


National Cooperative Highway Research Project (NCHRP) 9-49, which was completed in 2013, developed guidelines for warm mix asphalt (WMA) mix design and quality control to identify and minimize any possibility of moisture susceptibility. The objective of the current project, NCHRP Project 9-49B, was to validate and revise, if necessary, the thresholds in the guidelines developed in NCHRP Project 9-49. The research was based on a survey of the state departments of transportation (DOTs) and paving contractors to identify WMA mixtures with available field performance, mix design, and quality assurance data, including wet indirect tensile (IDT) strengths and tensile strength ratios, wet resilient moduli and ratios, and Hamburg wheel tracking parameters. The survey identified 89 field projects with either IDT or Hamburg wheel tracking results. These results were analyzed to validate the thresholds established for the tests in NCHRP Project 9-49. The key practical outcome of the research is a flowchart presented in this report for conditioning and testing WMA laboratory specimens in the mix design process that incorporates the validated thresholds.


Assuming that there has been thorough trial prepa ration and that the witnesses and evidence have been appropriately prepared, the critical day in court has finally arrived. A few simple amenities should be observed. First, the client should be properly dressed to present the kind of image that will complement the legal position and the testimony of the client. Appearances are im portant, particularly initial ones. Second, both attorney and client should arrive in the courtoom promptly. The initial irritation of the judge by having to wait for a party or a lawyer be comes a minor obstacle to be overcome, but never theless a prejudice to the case. Third, expect the judge to hold a pretrial conference immediately before the hearing. Judges like reasona ble attorneys and reasonable litigants. Any position taken by the attorney during the pretrial conference should be persuasive, but not overbearing. When representing the parent who wants to relo cate, the attorney should emphasize the urgent neces sity for the move and the fact that there may be no other realistic alternative residence for the client. Per haps even more important, the attorney should be


Since the discovery of the laser, a significant level of scientific research has relied heavily on advanced laser technology. The remainder of laser usage falls into the commercial, industrial and medical categories. Whether using single frequency lasers for high resolution spectroscopy, femtosecond lasers for ultrafast spectroscopy, scientists in many fields of research benefit from the unique properties of lasers. Significant achievements have taken place in the generation and amplification of ultrashort optical pulses from the femtosecond to nanosecond time scales. The emergence of new ultrafast optical modulation techniques has opened the way towards a new femtosecond laser technology based on solid state gain media. Femtosecond laser systems have proven their potential in research laboratories in a variety of applications that were previously unthinkable, in fields as diverse as material processing, photonic device production, microscopy, and biomedicine. Laser power, wavelength, linewidth, pulse length, and beam profile must all be optimized for a particular application. In the future, they may be a critical component of space based remote sensing systems, communications systems and laser medicine.


This paper proposes a method to assess the impact of the uncertainty in electric vehicle (EV) charging loads on system static performance reflected through the resulting uncertainty in system states, i.e., bus voltage magnitude and phase-angles. Historical EV charging data is fit to a Gaussian mixtures model (GMM), which can capture generic probability distributions. The GMM is then propagated through a linearized power flow model to yield a probabilistic characterization of the voltage magnitudes and phase-angles. As a direct consequence of the linear model approximation, the resulting characterization is also a GMM, the parameters of which can be computed in closed form. Numerical simulations involving the IEEE 33-bus distribution test system demonstrate the effectiveness of the proposed method to assess uncertainty in system states.


This paper addresses the problem in academic environment where the balance must be found between academic freedom and IT security challenges that every education and research organization must face today. The proposed approach includes risk management model which quantifies risks, based on actual threats and balances it with academic freedom that every academic environment employs. Preventive IT security measures that could be taken and solutions to improve IT security in academic environment are discussed in this paper.


Background: The etiology of Crohn's disease (CD) is still unknown. It is believed that altered immunological function of intestinal mucosa contributes a significant role to the pathogenesis of CD. Aims: To investigate the role of signal transducers and activators of transcription 3 (STAT3) in the pathogenesis of trinitro-benzene-sulfonic acid (TNBS)-induced experimental colitis of mice. Methods: TNBS-induced experimental colitis was constructed in mice. STAT3 antisense oligonucleotide (ASON) was administered intracolonally on day 3. The mice were sacrificed on day 7. The lamina propria mononuclear cells (LPMC) were isolated from the inflamed mucosa. Apoptosis of LPMC was assessed by FACScan cytofluorometer. Western blot analysis was used to assess the expression of STAT3, pSTAT3, Bcl-2 and Bax. The levels of proinflammatory cytokines tumor necrosis factor (TNF)-α and interferon (IFN)-γ in colonic tissue were measured by enzyme-linked immunosorbent assay (ELISA). Results: The expression of pSTAT3 in colonic mucosal LPMC of TNBS-induced colitis mice increased; the expression of Bcl-2 was up-regulated and Bax down-regulated, while the levels of proinflammatory cytokines TNF-α and IFN-γ in inflamed colonic tissue increased significantly. In STAT3 ASON-treated mice, the expression of STAT3 and pSTAT3 decreased; Bcl-2 expression increased and Bax expression decreased. Levels of TNF-α and IFN-γ in the inflamed colonic tissue also decreased markedly. Conclusions: STAT3 via modulating the secretion of proinflammatory cytokines and the expression of LPMC apoptosis-related protein, plays a significant role in the pathogenesis of TNBS-induced experimental colitis. Inhibiting the activation of STAT3 can significantly ameliorate the degree of severity of TNBS-induced experimental colitis in mice.


Recent work has shown advantages of incorporating knowledge graphs (KGs) into BERT (Devlin et al., 2019) for various NLP tasks. One common way is to feed entity embeddings as an additional input during pre-training. There are two limitations to such a method. First, to train the entity embeddings to include rich information of factual knowledge, it typi-cally requires access to the entire KG. This is challenging for KGs with daily changes (e.g., Wikidata). Second, it requires a large scale pre-training corpus with entity annotations and high computational cost during pre-training. In this work, we efficiently construct entity embeddings only from the type knowledge, that does not require access to the entire KG. Although the entity embeddings contain only local information, they perform very well when combined with context. Furthermore, we show that our entity embeddings, constructed from BERT's input embeddings, can be directly incorporated into the fine-tuning phase without requiring any specialized pre-training. In addition, these entity embeddings can also be constructed on the fly without requiring a large memory footprint to store them. Finally, we propose task-specific models that incorporate our entity embeddings for entity linking, entity typing, and relation classification. Experiments show that our models have comparable or superior performance to existing models while being more resource efficient.


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Flexible octopus arms exhibit an exceptional ability to coordinate large numbers of degrees of freedom and perform complex manipulation tasks. As a consequence, these systems continue to attract the attention of biologists and roboticists alike. In this article, we develop a three-dimensional model of a soft octopus arm, equipped with biomechanically realistic muscle actuation. Internal forces and couples exerted by all major muscle groups are considered. An energy-shaping control method is described to coordinate muscle activity so as to grasp and reach in three-dimensional space. Key contributions of this article are as follows: (i) modelling of major muscle groups to elicit three-dimensional movements; (ii) a mathematical formulation for muscle activations based on a stored energy function; and (iii) a computationally efficient procedure to design task-specific equilibrium configurations, obtained by solving an optimization problem in the Special Euclidean group SE(3). Muscle controls are then iteratively computed based on the co-state variable arising from the solution of the optimization problem. The approach is numerically demonstrated in the physically accurate software environment Elastica. Results of numerical experiments mimicking observed octopus behaviours are reported.


This paper presents a spatial-temporal single harmonic switching (STHS) transmitter array architecture with enhanced efficiency in the power back-off (PBO) region. STHS is an electromagnetic and circuit co-designed and jointly optimized transmitter array that realizes beamforming and back-off power generation at the same time. The temporal dimension is originally added in STHS to achieve back-off efficiency enhancement, which can be combined with conventional PBO enhancement methods such as Doherty amplifiers and envelope tracking. The design is validated through a simulation of a two-stage power amplifier in 65-nm CMOS at 77 GHz, which achieves a peak drain efficiency (DE) of 24.2%, a 22% DE at 3-dB PBO, 16% DE at 6-dB PBO, and 10.2% at 9-dB PBO. The efficiency exhibits a 57% improvement at 3-dB PBO, 100% improvement at 6-dB PBO, and 190% improvement at 9-dB PBO compared with class A/B amplifiers.


: A novel device for intracellular microinjection was designed to integrate controlled pressure microinjection and electrical microinjection (iontophoresis) with membrane poten tial recording and a limited capacity for turgor measurement. The validity of the device was verified by microinjection of a mixture of the fluorescent probes, Texas Red sulfonyl chloride and 10 kDa-LYCH-dextran conjugate, into epidermal cells of var iegated Coleus blumei leaves. Continuous monitoring of the fluorochrome movement by confocal laser scanning microscopy evidenced that the novel device succeeded in differential micro-injection of the fluorescent probes by pressure and iontophor esis. The multifunctionality of the microinjection system was further demonstrated by showing that both microinjection methods functioned in parallel with cellular membrane poten tial measurements in Vicia faba stem tissue. Advantages and prospective applications of the integrated microinjectionjmem-brane potential measurement system are briefly discussed.


Presently, one of the most promising sources for a future of abundant, lowemission, and efficient energy comes in the form of nuclear fusion. However, in order for it to become a reality, fusion technology must overcome the obstacle of plasma confinement. Utilizing the tokomak based design for magnetic plasma confinement; ITER is currently developing a fusion reactor to prove its commercial viability. The purpose of this research was to determine the feasibility of pulling superconducting cable with a press-fit grip sleeve that utilizes friction to generate a gripping force. Such a design is being considered by ITER to integrate (join) 800 m long sections of superconducting cable and conduit for use in toroidal field plasma confinement coil construction. In order to see if friction alone had the potential to withstand the required pulling load, eight grip sleeve samples were subjected to monotonic tensile loading until failure (sleeve slippage) occurred. It was also important that the grip could withstand the variable loading that will likely occur during the pulling process due to friction between the cable and conduit. Therefore, a period of cyclic loading, prior to tensile loading, was incorporated into the testing regimen. Based on the results of each experiment, additional modifications were made until the sleeve's gripping strength exceeded that of the weld joint used in the design, meaning the physical limitations of the grip sleeve had been reached. Once the design was optimized, additional samples were tested under identical conditions to establish repeatability. In addition, Finite Element Analysis was used to obtain better insight into the deformation behavior of the cable. Based on the findings of this research, it was determined that a 300 mm long press-fit sleeve with a 25.4 mm long reinforcement grip ring is capable of supporting a 116 kN (26,000 lbf) to 126.5 kN (28,500 lbf) tensile load, with little to no adverse effects from fatigue testing. Since this value exceeds the 8,000 lbf load used by a Russian team to perform this same task, it can be concluded that the press-fit grip design is capable of performing the required cable pull with a generous safety factor.


Evaluating dynamic properties of geomaterials is an essential step for solving geotechnical earthquake engineering problems. The shear stiffness-reduction curves of soils are commonly presented in normalized form and have many applications in equivalent-linear and nonlinear dynamic analyses. In this study, a radial basis function (RBF) neural network model was developed to predict normalized shear modulus of cohesive soils. The most important factors that affect this parameter include effective confining pressure, shear strain, and plasticity index. The comprehensive database used for the development of the model was obtained from previously published experimental results. Validation of the model performance was carried out by using centrifuge tests results. A parametric analysis was then performed to evaluate sensitivity of the proposed model to variations of the influencing parameters. The results indicate that the neural network model could provide predictions more accurate than those obtained by the previous models. ARTICLE INFO


Abstract Linked Data (LD) is a well-established standard for publishing and managing structured information on the Web, gathering and bridging together knowledge from different scientific and comme...


A fuzzy control strategy on viscosity of a polymeric melt during the extruding processes is proposed to ensure producing the quality-consistent end products. Because the viscosity model in the control system varies with respect to different conditions of the system command (e.g., screw speed), we focus on using a fuzzy controller accomplished with a fuzzy modeling technique to solve the model-variant viscosity control system. Also, system stability analysis is presented. According to the simulation and the implementation results, better performances and a suitable using method are concluded.


Many health economists, ranging from Democratic advisor Jonathan Gruber1 to the Heritage Foundation,2 have argued that tax subsidies for employer-paid health insurance encourage over-insurance and are highly regressive, directed mainly to higher-income families. We beg to differ. The subsidies meet the usual definition of progressivity: they taper down (as a percentage of income) as income rises. Ending them would inflict a regressive tax increase, taking a larger share of income from insured near-poor and middle-class families than from the wealthy. The confusion may arise from the dazzlingly large sums that high-income families gain from these tax subsidies. According to a . . .


Fresh flowers of Tagetes erecta L., the flavonoid was isolated by extraction and fractionation with different solvents. It was then identified as patulitrin (10mg/100ml) by various tests. It was then subjected to disc diffusion assay to assess its antibacterial potentials against Alcaligens faecalis, Bacillus cereus, Campylobacter coli, Escherchia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus vulgaris, Streptococcus mutans and Streptococcus pyogenes. The flavonoid possesses antibacterial activity against all the tested strains and shows maximum zone of inhibition for Klebsiella pneumoniae (29.50 mm). T.erecta flavonoid patulitrin is one of the potential elements for therapeutic use.


An increasing number of studies indicate that changes in cytosolic free Ca2+ ([Ca2+]c) mediate specific types of signal transduction in plant cells. Modulation of [Ca2+]c is likely to be achieved through changes in the activity of Ca2+ channels, which catalyse passive influx of Ca2+ to the cytosol from extracellular and intracellular compartments. Voltage‐sensitive Ca2+ channels have been detected in the plasma membranes of algae, where they control membrane electrical properties and cell turgor. These channels are sensitive to 1,4‐dihydropyridines, which in animal cells specifically affect one class of voltage‐regulated plasma membrane Ca2+ channel. Ca2+‐permeable channels with different pharmacological properties have been found in the plasma membrane of higher plants. Recent evidence suggests the existence of two discrete classes of Ca2+ channel co‐resident in the vacuolar membrane (tonoplast) of higher plants. The first is gated by inositol 1,4,5‐trisphosphate, and bears a number of similarities to its animal counterpart which is located in the endoplasmic reticulum (ER). The second tonoplast Ca2+ channel is voltage‐operated. However, the specific roles of these tonoplast channels in signal transduction have yet to be elucidated.


York Police in York are appealing for information after a 24-year-old woman was followed home and attacked by a man. The woman was walking home after ...


In dry sub-humid and semi-arid regions, where rainfall is limited to only a few months per year, rainfall is the most important factor affecting crop growth and yield. Every year, farmers are faced with the crucial question of when to start planting. Do the first rainfalls after the dry season resemble the onset of the rainy season (ORS) or not? A fuzzy logic-based algorithm for estimating the ORS and the optimal planting date was developed. It is based on rainfall data and accounts for agriculturally meaningful aspects. The ORS algorithm, which calculates the planting date for each year, was coupled to the physically-based crop model CropSyst. A Monte Carlo approach was applied to generate annual planting dates from 1979 to 2003. Therefore, the definition constraints, which are allowed to vary within reasonable parameter ranges, are generated randomly. The averaged crop yield served as a performance measure for each realization. The parameter range of the best realizations is retained. Various iterations are necessary to obtain a robust set of "optimal" definition parameters. The coupled ORS definition-crop modelling system was applied for two different crop species and five different observation stations across Cameroon for the period 1979—2003. It is shown that the derived "optimal" planting dates would allow for significantly increased crop yields compared to the existing planting rules in Cameroon.


Sedudo Waterfall Tradition is a ceremony that has passed from ancient times until now, the culture of Siraman since the Majapahit era and the glory of Islam in Java Island, is often used to bathe the weapons of the heirlooms of the former kingdom. Relic of Indonesian culture still preserved by government and society in Ngilman Village, Sawahan Sub-District, Nganjuk Regency, East Java. In this tradition of balustrade various ceremonial traditions, better known as Siraman Sedudo Waterfall. This objection is aimed at 1) the happiness of selametan in one suro, 2) including the procession of the anniversary of Nganjuk, 3) showing the handicrafts, Javanese art and introducing Sedudo Waterfall tour in Ngilman Village, Sawahan Sub-District, Nganjuk Regency, and showing among other people in the region. The benefit is to increase the regional income of the Ngilman community in the Nganjuk regency. With the processions at this event, the many stages that must first pass the gambyong dance performances are six female dancers, then to take twelve to get water with twelve pejakas. After completing the tradition of chopping girls and pejaka begin to enter the sedudo waterfall that has been prepared to take the water fell from the top, just under the waterfall and bring the water in the kendil directly to the big pot, to be stored and enshrined in Pendopo Kabupaten Nganjuk.Semua done in the procession there is a meaning of its own.


AIM: To evaluate resistive index in various stages of liver cirrhosis and to determine its significance in developing hepatorenal syndrome. METHODS: Study included 60 cirrhotic patients divided into 4 groups (15 patients each): compensated liver cirrhosis (group A), diuretic responsive ascites (group B), refractory ascites (group C), hepatorenal syndrome (group D) and ten healthy persons as control group (E). All patients subjected to detailed history taking and clinical examination. Laboratory investigations included simple urine analysis, complete blood picture, liver function tests, blood urea and serum creatinine, serum sodium and serum potassium, and protein concentration. Ultrasonographic examination and renal duplex Doppler were under taken to assess the Resistive index. RESULTS: The RI of interlobar and arcuate arteries were significantly higher in all patient groups than in control group (p <0.05), the RI was significantly higher in patients with refractory ascites than in patients with diuretic responsive ascites, and also in patient of diuretic responsible ascites than in patients with compensated cirrhosis (p < 0.05), in patient with hepatorenal syndrome than in patient with diuretic responsive ascites and patients with compensated cirrhosis (p<0.05). Also Creatinine levels & blood urea levels in patients with the hepatorenal syndrome was significantly higher than that of other different groups (p<0.05) but there was no significant change in creatinine levels between patients with compensated cirrhosis and control group. While creatinine levels in patient with diuretic responsive ascites was significantly higher than that in patient with compensated cirrhosis (p<0.05) there was no significant change between patient with diuretic responsive ascites and patient with refractory ascites. CONCLUSION: Resistive index increases with degree of hepatic decompensation. Renal duplex ultrasound is a non- invasive, simple and easy method to study intrarenal hemodynamics in patients with liver cirrhosis INTRODUCTION: Renal hemodynamic changes with intense intrarenal vasoconstriction begin early in the course of liver disease before changes in the level of serum urea and serum creatinine1. Patients with liver cirrhosis and portal hypertension develop circulatory dysfunction characterized by disturbance in systemic and renal hemodynamics. Hepatorenal syndrome (HRS) is a "functional" and reversible form of renal failure that occurs in patients with advanced chronic liver disease. The distinctive hallmark feature of HRS is the intense renal vasoconstriction caused by interactions between systemic and portal hemodynamics. This results in inactivation of vasoconstrictors and suppression of vasodilators in the renal circulation. Although the assessment of kidney function is of great clinical importance in patients with liver cirrhosis and ascites, serum creatinine and even


The aim of this paper is to present some existence results for a system of two coupled second order differential equations with three point nonlocal boundary conditions. The main tool used in the proofs is Guo-Krasnosel'skii's fixed point theorem. An example is included to illustrate the results.


Paper 18: Stephen K. Lucas, "Approximations to π derived from integrals with nonnegative integrands," American Mathematical Monthly, vol. 116 (2009), p. 166–172. Copyright 2009 Mathematical Association of America. All Rights Reserved.


0 HAVE national culture and be free from barbarism seems to be the primary moral requisite for a people which is to exercise the rights of war, if not the rights of peace. Russia has been shown to be primitive, England practical, Germany transcendental, France aesthetical. In our own country, the sense of national unpreparedness along lines martial seems as yet to have been unaccompanied by the feeling of unfitness in things fine and intellectual. Can we fight without arms? Should we fight without ideals? As far as France is concerned, no one seems to have thought to question the right of the French to conserve their national ideals, so that it is not inappropriate but quite fruitful to inquire concerning the sincerity and consistency with which the Gallic mind asserts its artistic and intellectual principles. No critic dare repudiate the Gothic of the French nor deny that in France the drama received a treatment worthy of the classic master; if, in painting, France had no Renaissance comparable to the Florentine, the Barbizon men of 1830 revealed the fact that "painting" may vie with "art." Granted that French art may, at times, become Parisian, granted further that Gallic aestheticism has known the flamboyant, the decadent, the risque, the superiority of the French creative gerxiis needs no apology. But, the historical fact of culture is not necessarily one with the internal, spiritual principle of belief in culture; hence, one must meet French enlightenment with the query concerning the authenticity of that which the French genius has produced. Is French fineness culture or dilettantism? Has France shown faith in her works? Where the cultureproblem is raised, it must be admitted that France has been the leader in the attempt to scrutinize the work of


Experts now recommend that all Helicobacter pylori infections be eradicated unless there are compelling reasons not to. As with other infectious diseases, effective therapy should be based on susceptibility. H pylori infection is an infectious disease and should be treated like one, with due consideration of resistance.


Music education is an important university quality education is one route of transmission,which help to promote physical and mental health of university students to promote ideological exchanges,cultivate character and temperament perfect for building a harmonious campus has a positive effect.As information technology and the international community diversity,pop culture,the ideological impact of learning and living,making music,profound changes in aesthetic values,the value of this musical culture has both positive and negative effects,how to properly carry out the quality of training music to build a good musical aesthetic standards,improve their musical taste and artistic accomplishments of contemporary college students research focus.


The purpose of this study was to provide an understanding of how disability is addressed in the Journal of Counseling and Development (JCD), the flagship journal of the American Counseling Association. A review of disability content in JCD was compared with a review of disability in Social Work (SW), the flagship journal of the National Association of Social Workers. A series of between and within analyses for JCD and SW addressed the frequency, focus areas, and trends concerning how both journals addressed disability content over their histories. Overall, SW published a higher rate of disability content articles. Mental health was the most common disability domain addressed in both journals; however, JCD has published most of its disability content articles on mental health over the past two decades. The findings of the present study are discussed concerning prior research, historical events, and implications for accreditation.


ABSTRACT Introduction: Black cumin (Nigella sativa) oil is a natural antibacterial product containing thymoquinone. Thymoquinone is a powerful antibacterial substance towards gram-positive bacteria. The research objective was to compare the inhibitory effects of black cumin oil, Cresophene® and Ca(OH) 2 towards the growth of Staphylococcus aureus. Methods: Experimental laboratory by taking Staphylococcus aureus from deciduous teeth pulp necrosis that has been isolated in Brain-Heart Infusion (BHI) medium. Inhibitory of black cumin oil, Cresophene® and Ca(OH) 2 were measured by making three different 6 mm diameter wells contained each substances. Data then analyzed by two-way ANOVA using statistical analysis program. Results: Cresophene® had the largest inhibitory zone with the average zone was 32 ± 0.05mm and stable from the 1 st day until the 4 th day then decreased on the 5 th day and remain stable until the 7 th day. Ca(OH) 2 had average inhibitory zone of 15.9 ± 0:10 mm and remain stable from the 1 st day until the 7 th day. Black cumin oil had average inhibitory zone of ± 7.9 ± 0.2 mm and remain stable from the 1 st day until the 7 th day. Conclusion: The inhibitory zone towards Staphylococcus aureus isolated from deciduous teeth pulp necrosis consecutively was Cresophene®, Ca(OH) 2 and black cumin oil. Keywords : Staphylococus aureus, Black cumin oil, Cresophene® , Ca(OH) 2 , Inhibitory zone


Three-component photoresists were prepared from hyperbranched polyester,multifunctional(acrylate) monomer and photoinitiator.The hyperbranched resin had —COOH,—OH and methacryloxy groups at their chain ends.The dried resist on glass substrate showed an H~HB pencil hardness.A high sensitivity with(E_(0)~)5.5 ×10~(-3) J/cm~(2) and a high contrast with γ~8 were obtained for the resist exposed with a mixed UV light and developed with TMAH aqueous solution.Sensitivity and contrast upon UV exposure were tunable by development solution and the amount of photoinitiator.The resist exhibited a unique linear relationship(between) exposure energy and etching depth.This property provides a controlling of surface profile of micro(optical) elements fabricated with photoresists.Microlens arrays(200 μm×200 μm) were prepared from these photoresists with a moving-mask.


The problem of two identical chaotic systems with noise is investigated in this article.The instantaneous mean square error(e) is analyzed based on the Jacobian equation of the response system.A synchronization scheme is proposed here,and the time-varying coupling parameter sequence used in this new scheme is obtained by minimizing the instantaneous e.Numerical simulation shows that two 2-D logistic map reach the state of synchronization with the time-varying synchronization method.


We generalize the school choice problem by defining a notion of allowable priority violations. In this setting, a weak axiom of stability (partial stability) allows only certain priority violations. We introduce a class of algorithms called the student exchange under partial fairness (SEPF). Each member of this class gives a partially stable matching that is not Pareto dominated by another partially stable matching (i.e., constrained efficient in the class of partially stable matchings). Moreover, any constrained efficient matching that Pareto improves upon a partially stable matching can be obtained via an algorithm within the SEPF class. We characterize the unique algorithm in the SEPF class that satisfies a desirable incentive property. The extension of the model to an environment with weak priorities enables us to provide a characterization result that proves the counterpart of the main result in Erdil and Ergin (2008).


Developments in the Middle East and Southwest Asia after the events of September 11, 2001, suggest that the historical geopolitical imperatives driving United States policy in the region since World War II continue to be salient. The context in which the United States is now operating, however, is fundamentally different from the zero-sum rivalry between great powers that characterized the Cold War. In the postCold War/post-9/ 11 world, the "great game" of imperial rivalry has been transformed.' On one hand, regional powers (states capable of projecting themselves regionally) that possess or seek to possess weapons of mass destruction have become the most serious threat both to stability and to vital U.S. interests in the region.2 Among international, or great, powers, on the other hand, the threat of nuclear war has receded; common threats such as regional wars and international terrorism are facilitating a recognition of common interests; old rivals have become allies of a sort; and the great game is morphing into a clash of values and principles that cuts across traditional borders and cultures, posing serious problems but also providing opportunities for enlightened leadership. The new great game is not a conflict between civilizations, as some would have it; rather, it is a conflict within states, within cultures, and within an increasingly global community over the values and ideas that underpin modernization and the norms and direction of modern civilization-a conflict being played out on a global playing


Letters from Ann Clar k(Mrs Weston) to sister Jane dated around 1831 regarding gowns, bonnets and ribbons, building at Hythe's New Zealand pine flooring. From the family papers of William & John Clark of Cluny, Bothwell 1812-1872 : Royal Society Collection - RS8/F6-7, RS8/F6-8 & RS8/F6-15


A 62‐year‐old male presented with generalized weakness and abdominal discomfort since the past 4 months; there were no other significant complaints. On examination, the patient was pale and his abdominal palpitation revealed an enlarged, firm, nontender splenomegaly 10‐cm below the costal margin. His complete blood count results were as follows: white blood cell (WBC) count, 3.0 × 109/L; red blood cell count, 2.37 × 1012/L; hemoglobin, 6.7 g/dl; and platelet count, 30 × 109/L. A peripheral blood smear demonstrated normocytic normochromic red cells with a WBC differential count of 22% polymorphs, 70% lymphocytes, 2% monocytes, 1% eosinophils and 5% atypical cells [Figure 1a and b]. Bone marrow aspiration was not possible ("dry tap"). The hematoxylin and eosin staining of the trephine bone marrow biopsy showed an infiltration by cells with a characteristic "fried egg" appearance of the cytoplasm [Figure 2].


Localization is one of the fundamental tasks in wireless sensor network. Measuring time of arrival (TOA) and time difference of arrival of a signal (TDOA) are two widely used criteria for localization. In TOA based schemes target must be synchronous with anchors while target can be asynchronous with anchors in TDOA schemes. In this paper, we propose a target localization scheme based on measuring TDOA for inhomogeneous underwater environment. One of the properties of inhomogeneous underwater is that waves travel over curved path due to the inhomogeneity of the underwater. This phenomenon makes TDOA based localization in underwater a different problem from localization in terrestrial wireless sensor network. Our proposed TDOA based localization is developed by iterative algorithm. Simulation results shows that while our proposed underwater-TDOA algorithm converges to the Cramer Rao Lower Bound (CRLB), it outperforms the line-of-sight-TDOA algorithm in accuracy sense and also underwater-TOA algorithm for localizing an asynchronous target.


We describe the successful use of cannula cricothyroidotomy and the Rapid-O2™ oxygen insufflation device (Meditech Systems Ltd, Dorset, UK) for rescue of a can't intubate/can't oxygenate (CICO) scenario in a patient with severe airway haemorrhage post-debridement of laryngeal amyloidosis. This case highlights the practical utility of a cannula technique for CICO rescue when appropriate equipment is used and when institutional measures are taken to prepare for this rare anaesthetic crisis.


The minimally invasive approach of arthroscopy means less pain and faster recovery time for patients compared to open surgery. However, it implies a high difficulty of performance. In this paper, a functional prototype of a virtual reality simulator for training wrist arthroscopic surgery is introduced. This simulator allows medical students as well as surgeons to interact with anatomical structures by modeling and operating on virtual objects displayed on the computer screen. A 3-D virtual representation of the bones constituting the wrist of a patient is shown. Also, algorithms that model objects using the convex hull approaches and simulate real time collision detection between virtual objects during the training on the operation are presented. In addition, a force feedback device is used as a haptic interface with the computer simulation system. This leads in the development of a low cost system that is used by trainees with the same benefits as professional devices. In this regard, the wrist arthroscopy can be simulated and medical students can easily acquire the system and can learn the basic skills required with safety, flexibility and less cost.


The dynamical mechanism of the formation and development of Chinese parks of sciences is analyzed through expatiating on the definition and development background. Moreover,combining with the spatial distribution characteristics and existing problems of Chinese parks of sciences, some corresponding strategies and suggestions for their planning and management are put forward.


Purpose
This paper aims to conduct a detailed analysis of the feasibility of issuing sukuk in China and examine the regulatory issues related to the issuance of sukuk in China.

Design/methodology/approach
This study uses SWOT analysis to explore China's internal and external environments related to the issuance of sukuks and examines the application of sukuks as an alternative financing instrument in China.

Findings
As a unique financial instrument, a sukuk can assist in meeting China's current financing needs. Moreover, it is feasible to issue a sukuk. China should be prepared to modify its legal system and set up a regulatory framework conducive to the issuance of sukuks. Furthermore, blockchain technology can be used to overcome certain limitations of sukuks.

Originality/value
This study provides a detailed analysis of sukuk issuances in China. This study discusses the issue of sukuk issuance in China from the perspective of finance and law.


Background : Skeletal tuberculosis constitutes about 1% of all tubercular cases. It usually affects the spine and long bones. Tubercular osteomyelitis of skull is a rare entity and therefore diagnosis is not suspected. Skull bones usually involves secondarily from the lung or lymph node focus. Biopsy in these cases confirms the diagnosis. Case Report : A 20 year male patient presented with gradually progressive headache, with multiple episodes of seizures. Magnetic resonance imaging (MRI) brain revealed heterogeneously enhancing extra-axial bi-frontal convexity mass lesion. Histopathology showed necrosis and many caseating as well as non-caseating well defined epithelioid granulomas. Conclusion : A high index of suspicion is important to recognize tuberculous involvement of the skull. Biopsy confirms the diagnosis.


The Human Rights Commission was established in July 2001. It was set up as a direct result of the Good Friday Agreement of 1998 which provided for the establishment of a Human Rights Commission in this jurisdiction and for a Human Rights Commission in Northern Ireland. Under the Good Friday Agreement, the Commissions are charged with promoting and protecting human rights in their respective jurisdictions and working together to improve the protection of human rights on the island of Ireland.

Sector: Community Development
Address: 4th Floor, Jervis House, Jervis Street, Dublin, Dublin
Phone: +353 (0)1 858 9601
Email: firstname.lastname@example.com


In 1987 we built our house in an area of natural bushland in the Melbourne suburb of Rowville, where three Eucalyptus spp. (Long-leaved Box E. goniocalyx, Silver-leaved Stringybark E. cephalocarpa and Peppermint Gum E. radiata) were already well-grown. It was not until 2008 that fruit-bodies of a large bolete Phlebopus marginatus began to appear on the ground under one of the Long-leaved Box trees. This fungus has grown in the same area most years since. I didn't see it in 2012, but it reappeared in the autumn of 2013, when it also grew near the Silver-leaved Stringybark.


Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is the most common inherited disorder of mitochondrial fatty acid β-oxidation in humans. To better understand the pathogenesis of this disease, we developed a mouse model for MCAD deficiency (MCAD−/−) by gene targeting in embryonic stem (ES) cells. The MCAD−/− mice developed an organic aciduria and fatty liver, and showed profound cold intolerance at 4 °C with prior fasting. The sporadic cardiac lesions seen in MCAD−/− mice have not been reported in human MCAD patients. There was significant neonatal mortality of MCAD−/− pups demonstrating similarities to patterns of clinical episodes and mortality in MCAD-deficient patients. The MCAD-deficient mouse reproduced important aspects of human MCAD deficiency and is a valuable model for further analysis of the roles of fatty acid oxidation and pathogenesis of human diseases involving fatty acid oxidation.


The Daozang contains forty odd texts or portions of texts which are devoted to one or another form of divination. These texts are of three main types: numerological and symbological exegesis related to the Yijing; oracle slip (qian) collections; mantic procedures, including texts of calendarology, hemerology, astrology, meteoromancy, topomancy, and physiognomy. The main interest of the first group is that it exists, for this reminds us that the Yijing is not the exclusive preserve of Neo-Confucians. Among the second group we take special note of the Huguo jiaji Jiangdong wang lingqian: it is the oldest extant text of its kind (1225-1227), and we have precise information about its composition and cultic use. ; But it is the third group which is of the greatest significance: in it we find texts which reveal the link between the divinatory almanacs of the pre-imperial period and Taoist calendarology of the Six Dynasties, texts of the early Song which help us to understand the relationship between the Dunjia system and Liuding rites, and texts which may represent an intermediary step between the Indo-Iranian astrology imported by the Buddhists during the Tang dynasty and the post-Song system of the horoscope (mingli xue).


Fashion has always been an essential feature in our daily routine. It also plays a significant role in everyone's lives. In this research, convolutional neural networks (CNN) were used to train images of different fashion styles, which were attempted to be predicted with a high success rate. Deep learning has been widely applied in a variety of fields recently. A CNN is a deep neural network that delivers the most accurate answers when tackling real-world situations. Apparel manufacturers have employed CNN to tackle various difficulties on their e-commerce sites, including clothing recognition, search, and suggestion. A set of photos from the Fashion-MNIST dataset is used to train a series of CNN-based deep learning architectures to distinguish between photographs. CNN design, batch normalization, and residual skip connections reduce the time it takes to learn. The CNN model's findings are evaluated using the Fashion-MNIST datasets. In this paper, classification is done with a convolutional layer, filter size, and ultimately connected layers. Experiments are run with different activation functions, optimizers, learning rates, dropout rates, and batch sizes. The results showed that the choice of activation function, optimizer, and dropout rate impacts the correctness of the results.


A stroller wandering on Boston's waterfront will find in one of the better known wharving districts a pier that is a prolongation of State Street (known as King Street in Colonial days), the financial avenue of the City. There will be a penetrating tang of fish in the vicinity, and well might this be so for practically the only vessels that put into this wharf are fishermen's schooners and smacks. There is certainly nothing pretentious about this quay, and yet if some of its rotting timbers only had the powers of speech, what a story they might tell. It is, indeed, Long Wharf, the center of Boston's expanding shipping interests from early Colonial days up to the middle of the nineteenth century. However, we do not have to wait for the old timbers to acquire speech in order to ferret out the romance of Long Wharf; for there are references to it in most Boston histories, and in addition there are numerous business papers of the pier's proprietors now deposited in the Baker Library.


www.nursingmanagement.com Patient handling and time outs: s a nurse leader, our challenges are many, and one universal concern is protecting staff from physical injuries related to patient handling. According to the Occupational Safety and Health Administration, healthcare workers suffer injuries and illnesses at twice the national average.1 In fact, in 2011, hospitals reported an incidence rate of 6.8 occupational injuries and illnesses per 100 full-time workers in comparison with 3.5 per 100 in all U.S. industries combined. Of the injuries and illnesses reported among nurses and unlicensed assistive personnel (UAP), nearly 50% were related to musculoskeletal injuries.2 An estimated 12% to 18% of nursing professionals leave the profession annually due to chronic back pain. Additionally, another 12% consider job transfers due to the high risk of patient-handling injuries.3 The CDC states, "The greatest risk factor for overexertion injuries in healthcare workers is the manual lifting, moving, and repositioning of patients, residents or clients... manual patient handling."4 At a time when the nursing profession must care for an aging population, as well as an increasing number of obese and morbidly obese patients, nurse leaders must work to create a healthy, safe work environment to retain nurses who are already in short supply.5 This article is about a 38-bed acute medical-surgical unit that faced this challenge directly and took control of safe patient handling and the health of its bedside caregivers.


For promoting the development of martial arts in university,this essay analyzes the current development of martial arts,concluding that the unsatisfactory situation is due to the lack of martial arts teachers,the adoption of traditional routines as teaching contents (which leads to the students' lack of interest in martial arts),the lack of venues and equipment,the lack of martial arts societies and public activities,and the lack of competitions between universities (which leads to the situation that no leaders pay much attention to it and teachers and students have no high competition consciousness).Based on these existing problems,some researchers have raised the following countermeasures: playing down traditional routines,learning techniques and focusing on practices.At last,this essay discusses the research approaches on university martial arts education.


This Article analyzes the importance of trust in securities investing and how guilt about breaching such trust has implications for securities regulation. Both U.S. federal securities laws and the regulations of the National Association of Securities Dealers impose high standards of professional conduct upon securities professionals. But exactly what are and should be the legal responsibilities of securities professionals remain the subject of much debate. In particular, courts disagree over when broker-dealers are fiduciaries of their clients. A legal consequence of a fiduciary relationship is a duty of fair dealing. This Article is the first to analyze the emotional, moral, and psychological consequences of broker-dealers' being fiduciaries. This Article explains how finding that securities professionals are fiduciaries can alter both expectations about securities professionals' behavior and that behavior itself, as well as cause those professionals to feel guilt from breaching their clients' trust or pride from honoring such trust. This insight has implications for the costs and benefits of finding a fiduciary duty. In particular, there is an emotional or psychological deterrence effect, in addition to the deterrence effect of monetary fines or legal sanctions, from finding a fiduciary duty. This Article demonstrates how fiduciary law can affect behavior even without extensive enforcement or severe legal penalties.


This paper studies dividend growth predictability without restricting conditioning information set to dividend yield alone. We highlight that predictability crucially hinges on how dividend growth is constructed. Dividend growth without reinvestment is significantly predictable both in-sample and out-of-sample by a number of economic fundamentals. The results are robust across subsamples. When dividend growth predictability is properly taken account of, it leads to a different picture of variance decomposition of returns. Contrary to the prevailing views, the cash flow news is important in driving stock price movement in aggregate level after incorporating dividend growth predictability.


484 those who simply cannot get enough of this fascinating era. It has less to offer academic specialists. Kentucky readers especially will appreciate the attention given to Henry Clay. Although the portrait of him is not flattering, it is surely accurate. That he could be so central to national politics in 1840 but by the end of the 1840s seem so strangely out of touch speaks to how much the country changed in this crucial decade.


A 75-year-old man undergoing emergency laparotomy for a ruptured abdominal aortic aneurysm in January 2001 was found incidentally to have a solid tumor of the jejunum 3cm in diameter, necessitating Y graft re-placement and partial jejunal resection. Microscopically, the tumor consisted of fascicles of spindle cells and stained positive for CD34 and KIT, leading to a histological diagnosis of gastrointestinal stromal tumor(GIST). Low mitotic figures(1 (cid:1) 50 high-power field)and a low MIB-1 labeling index(3%)evidenced no malignancy. Abdominal computed tomography showed an intrabdominal mass 8cm in diameter in September 2003, so we conducted laparotomy in October 2003, resecting the main omental tumor and 2 small nearby lesions. Micro-scopically, the tumor morphologically resembled the previous intestinal GIST, but mitotic figures were fre-quent(16 (cid:1) 50 high-power field).C-kit mutation analysis showed both tumors to have the same mutation at exon 11 of the c-kit gene(deletion of codon 564―576).The omental tumor was diagnosed as recurrent intestinal GIST. The patient is doing well 8 months postoperatively without any sign of recurrence.


Winter wheat is an important food crop. On the gross grain harvest and areas under crops it ranks first in global agriculture. In 2015 more than 2,2 ml ha of the sowing areas were cultivated in the Rostov region. The increase of it is going to be up to 2,4 ml ha to 2020. Nowadays grain branch of Russia is greatly influenced with several global factors, among which global climate warming, fertility decrease and new phyto pathogens effect.  Development of winter wheat varieties adapted to definite climatic conditions with a guaranteed of productivity increase is a solution to the problem of grain production stabilization. The article considers economic-biological characteristics of soft winter wheat variety of intensive type 'Rostovchanka 7'. The tested traits of the variety show, that fertilizing is the main agro technology which determines the amount of harvest of the variety. The variety of intensive type 'Rostovchanka 7' was introduced in the State Register of breeding achievements of RF from 2011. It's middle early, highly productive variety. Its grain productivity if 9,5 t/ha. It possesses a high resistance to common leaf and stem diseases of wheat. The flour and baking properties are excellent. The variety is included in the list of the most valuable wheat of Russia. The most valuable traits of the variety are its frost and drought resistance.


The present invention relates to a compound having a skeleton kolran for use in the treatment and / or prevention of FXR and TGR5 / GPBAR1 mediated diseases.


The present invention provides a chip coating module with nitegral packing and radiating structure, and aims at providing packed IC circuit board with simple production process, high heat radiating and fixing effect. It includes chip coating module and heat radiating structure; and the heat radiating structure is an integral coating layer.


This Focus Review describes the evolution of artificial proteases, which are synthetic catalysts for peptide hydrolysis that mimic the action of natural proteases. The evolution took place through discovery of catalytic centers for peptide hydrolysis, attachment of substrate-recognition sites to the catalytic centers, and the advent of target-selective artificial proteases. Application of the target-selective artificial proteases led to a therapeutic option for amyloid diseases, such as Alzheimer's disease and diabetes.


Coffee packaging colour is a factor used to attract consumer attention and generate sensory and hedonic expectations. This study aimed to understand the effect of colour packaging on consumer expectations. A cross‐sectional study with 432 volunteers was carried out using coffee packaging with black, red, green and yellow colours. Each coffee packaging was compared with another similar coffee packaging having the opposite colour in the chromatic circle (white, light blue, pink and dark blue colours). Results from volunteers using free word association show that important attributes related to coffee could be induced in the volunteers using food packaging with black, red and green colours. Furthermore, the white colour can also be used in coffee packaging; however, this colour was not correlated with warm products as expected in coffee. Finally, coffee packaging having pink, light and dark blue, as well as yellow colours was rejected by the volunteers, suggesting that those colours should be avoided in packaged coffee.


In-vehicle audio/video communication has recently received considerable attention in the automotive industry. First, because of the increasing number of audio/video oriented nomadic devices in the consumer electronic market and the requirement to integrate them in the car. Second, because the number of real-time audio/video based driver assistance systems is growing fast. So far, the interconnection of in-vehicle stream oriented devices has been performed by different and proprietary, automotive oriented network systems with limited transmission capacities. Ethernet provides good conditions for audio/video streaming, due to its high transmission capacity. But it unfortunately fails in providing adequate QoS. In this work, a new network architecture for in-car audio/video communication based on the Ethernet technology is introduced and solutions are proposed to extend Ethernet with QoS guarantees while keeping its cost low.


Abstract Data from the Finnish milk recording system consisting of records for the first three parities from a total of 66 554 Ayrshire and 9664 Friesian cows were analysed using REML methodology and sire model. Factors with statistically significant effects on body weight were: year, age and season of calving and lactation stage. The influence of the random herd effect was also evident. Within-herd herit-abilities for body weight in the first three parities were from 0.29 to 0.41 in Ayrshires and from 0.21 to 0.34 in Friesians. Genetic correlations between body weight and 305-day milk, fat and protein yields varied from +0.09 to +0.34 in the Ayrshire data and from -0.06 to +0.28 in the Friesian. Phenotypic correlations were slightly larger and positive in both breeds. Genetic correlations between body weight and fat and protein percentages were negative and phenotypic correlations were near zero.


ZnO thin films were grown by metal-organic chemical vapour deposition using methanol as oxidant. Rapid thermal annealing (RTA) was performed in an ambient of one atmosphere oxygen at 900 °C for 60 s. The RTA properties of the films have been characterized using scanning electron microscopy, x-ray diffraction, x-ray photoelectron spectroscopy, photoluminescence spectra and Hall measurement. The grains of the film were well coalesced and the surface became denser after RTA. The full-width at half maximum of rocking curves was only 496 arcsec. The ZnO films were also proved to have good optical quality. The Hall mobility increased to 43.2 cm2 V−1 s−1 while the electron concentration decreased to 6.6 × 1016 cm−3. It is found that methanol is a potential oxidant for ZnO growth and the quality of ZnO film can be improved substantially through RTA.


elementary treatises on Physiology published in this country of late J ears, have scarcely brought their information up to the level of the science which existed even at the time of their first appearance : and the rapid progress of physiological knowledge has now left them far in the rear. The works of Bostock, Elliotson, Mayo, and others, though confining much valuable matter, scarcely touch upon certain facts recently established, and views recently divulged, which at present give, to the


The main purpose of a democratic state is that of protecting the civil rights and liberties. The fundamental condition for a good government and for guaranteeing social and individual freedom is based on the the deployment of a democratic national security system. Geo-political movements and the globalization phenomenon are real challenges for the national security system, regarding organized crime, weapons of mass distruction, international terrorism. All these threats require flexible laws to allow the national security system to function and accomplish its objectives without tainting or restricting civil rights and liberties. For these reasons, both government and civil society have the opportunity and responsibility to work together in creating a formal agenda on public policy reforms regarding the protection of civil rights and liberties while redesigning the national security system.


Multiphase (more than three phases) is very much popular due to their eminent features compared to conventional three-phase counter parts. In order to drive the multiphase machine, it requires same phase input w.r.t the no of phases at the output. This paper mainly focuses on five phase, because even after failure of one phase, the performance does not degraded much. Voltage source inverters (VSIs) are used to feed the induction motor. voltage source inverters (VSIs) switches are ON and OFF precisely to control the output. In order to implement harmonic waveform characteristic, carrier based PWM (pulse width modulation) is performed. By using with and without third harmonic injection machine torque is highly improved. Using MATLAB software, the simulation results are presented in the form of computer traces and high traded performance of the machine are discussed.


The novels of "Orphanage Consciousness",represented by Wu Zhuoliu's The Asian Orphan,reveal Taiwan intellectuals' embarrassing situation and survival experience in that special historical background during the Japanese colonial period.The journey of root-seeking and atonement of Hu Daming,typical of Taiwan intellectuals,was the very representation of their efforts to overcome the "orphanage consciousness",but not the "Taiwanese consciousness" so called by today's separatists,nor the justification for "Taiwan Independence".


Descriptive reports of South Wales English indicate front rounded realizations of the nurse vowel (e.g. Wells 1982; Collins & Mees 1990; Mees & Collins 1999; Walters 1999, 2001). However, the specific phonetic properties of the vowel are not depicted uniformly in these studies. In addition, they have relied entirely on auditory descriptions, rather than instrumental measurements. The study presented here is the first to provide a systematic acoustic and articulatory investigation of the nurse vowel in South Wales English, and to explore its relationship to realizations of Standard Southern British English /ɜː/ and Standard German /øː/. The results indicate systematic differences between the three vowels, with the South Wales English vowel produced with an open rounded lip posture, yet the acoustic characteristics of an unrounded front vowel. Implications for the notion of 'front-rounding' are discussed.


Despite improved methods for detecting and treating many forms of cancer, ethnic and racial minority groups continue to experience higher rates of cancer-related morbidity and mortality compared with Whites ([1][1]). Consequently, reducing and ultimately eliminating cancer disparities is now a


Dielectric spectroscopy has been employed to study the local and global dynamics of polyisoprene in the asymmetric star (polystyrene)(polyisoprene) 2 (SI 2 ) and in the 3-miktoarm star terpolymer (polystyrene)(polyisoprene)(polybutadiene) (SIB). All measurements refer to the ordered phase where PS cylinders are embedded on the I and I/B matrix, respectively. Effectively, we are studying the local and global dynamics of tethered PI chains in two environments : one made by I-chains (SI 2 ) and another by the I/B-chains (SIB). At low temperatures, the PI local segmental dynamics in SI 2 and SIB are different, reflecting the modification of the local friction by introducing the faster PB chains in the latter. At higher temperatures, however, this effect diminishes due to the demixing of I and B. To explore the thermodynamic and mobility effects on the global dynamics, we have studied, respectively, a ternary blend composed of PI, PB, and PS and binary blends of SIB and SI 2 with short PB chains. The PI global dynamics in SI 2 and SIB resemble the dynamics of PI stars with additional entanglement effects in the latter.


Quincke first suggested in 1879, and it is now generally agreed, that the direct cause of reflux oesophagitis is destruction of tissue by gastric or occasionally intestinal secretions, however odd it may seem for an organ to be at risk from the legitimate activities of its neighbours. In fact, the only tissue naturally immune to peptic digestion is the surface epithelium of the gastric mucosa, not even the whole thickness of that membrane.


This study aims to identify the factors that influence employee's perception towards sexual harassment at the workplace. The employee's perception was investigated from related aspect such as, level of awareness, work environment, organizational policy and preventive actions. The aim of this research is to identify factors that lead to sexual harassment at the workplace in
Malaysia. Its objectives are to identify a significant relationship between level of awareness, work environment, organizational policy and preventive actions and employee's perception towards sexual harassment as well as to identify the differences between gender and employee's perception towards sexual harassment and to identify dominant factor that leads to sexual
harassment at the workplace. This research design is quantitative study using survey methodology whereas a questionnaire designed by the past researchers was randomly distributed to 60 employees at the supermarket in Kota Samarahan, Sarawak. Data processing was analyzed
using Statistical Package for the Social Science (SPSS 15.0) software to find the frequency, mean and standard deviation. Meanwhile, Independent T-test, Pearson Correlation Analysis, and Multiple Regression were used to analyze the hypotheses. The findings showed that there is a significant relationship between work environment and employee's perception towards sexual harassment. However, the other finding indicates that there is no significant relationship between level of awareness, preventive actions and organizational policy with employee's perception towards sexual harassment. This research fording also found that there is no difference between gender and employee's perception towards sexual harassment at the workplace. Meanwhile, Multiple Regression Analysis was used to identify dominant factor that influence employee's perception towards sexual harassment at the workplace and the result showed that work environment is the dominant factor which 14.2% changes in employee's perception towards sexual harassment was caused by work environment.


Compared with the stable orders of traditional manufacturing, cloud manufacturing (CMfg) fulfilled with masses of random orders, so the CMfg server needs an algorithm with low time and space complexity to prevent the server from crashing due to excessive instantaneous data. Besides, the random changes of manufacturing resources and service must be considered when establishing a scheduling model for CMfg. To solve this problem, we propose an adaptive Deep Q-Networks (ADQN) method with a resizable network that converts cloud manufacturing scheduling problems with multiple objectives into specific reinforcement learning goal and can adapt to changing environments. Our experimental results show that ADQN is comparable to other real-time scheduling methods, the average subtask completion time and the standard deviation of occupation obtained by ADQN keep at a low level.


This quotation, cited by Greil Marcus in his 1989 "secret history" Lipstick Traces, is, according to the author himself, probably apocryphal. Yet it remains the trope animating most, if not all, punk rock epiphanies—the unsuspecting fan is transformed by a heretofore unknown approach to rock and roll that fundamentally changes not only their understanding of music itself, but also how they view both the world and their place in it. There are multitudes of these early empowering punk rock moments (mine was in 1977 at my first Ramones gig) and, taken as a whole, they function as the foundation upon which the history of punk is built. For many in the US and the UK it was the Sex Pistols who defined and authenticated—attitudinally, musically, and sartorially—all that was presumed to be quintessentially punk. A band that seemed to encapsulate a feeling redolent of 1976 Britain where "[a]pocalypse was in the air and the rhetoric of punk was drenched in apocalypse: in the stock imagery of crisis and sudden change" (Hebdige 27). When the Sex Pistols made their live debut on 6 November 1975 opening for pub rockers Bazooka Joe at St. Martins College of Art in London (a performance silenced after only 20 minutes), no one could have imagined that, in less than a year, they would appear on Tony Wilson's Manchester-based program So It Goes and debut their forthcoming single "Anarchy in the UK." Released four months later the song was "[a]n index of [the Sex Pistols'] increasing ambition, their wish to get into the world beyond the confines of the music industry, it was a call to arms, delivered in a language that was as explosive as the implications of the group's name" (Savage 204). Furthering the controversy surrounding the song was the band's drunken, expletiveladen appearance on the Bill Grundy Show, one that the tabloidDaily Mirror decried as "The Filth and the Fury," an expression of loathing that the band would ultimately embrace. From that moment, the career of the Sex Pistols played out in fast forward: three more singles, one official LP released in October, 1977, the sacking of bassist Glen Matlock and the hiring of the cartoonish and tragically self-destructive Sid Vicious, until the end came after a shambolic gig at San Francisco's Winterland on 14 January 1978. Despite a few excellently received and financially lucrative reunion tours, there has been no new music since 1978. In that sense, the Sex Pistols may have burned out but never really faded away. They remain always present when the words "punk rock" are uttered.


The principal electric characterstics of half-wavelength transmission lines are discussed taken into account possible voltage transients resulted from asymmetric faults. Although this non-conventional technology has some attractive advances for electric power transmission through long distances, if compared to well-established HVDC and HVAC systems, important issues should be investigated concerning overvoltage levels along the transmission line due to temporary asymmetric operation conditions, e.g. phase-to-ground faults. Depending of the type of fault and location along the half-wavelength transmission line, ovenroltage levels at some points through the line exceed 1.8 p.u. Thus, since some critical fault occurrences and overvoltage location are known, an alternative method for ovenroltage suppression is proposed by using ZnO surge arresters directly at the phases in parallel with the tower insulators.


The utility model relates to an automatic assembling machine for battery covers, which comprises a material-loading device, a positioning device, a material-loading device for a primary vibrating disk, a material-loading device for a secondary vibrating disk, a primary stamping device, a secondary stamping device, a short-circuit detecting device, a placing device for qualified products, a placing device for disqualified products, and a device for detecting whether products exist. The devices of the assembling machine are installed on an operating platform surface, a turnplate is installed in the middle part of the operating platform surface, a mould for positioning the battery covers is installed on each station of the turnplate, and the devices of the assembling machine is clockwise installed on the operating platform surface around the turnplate in series. The assembling devices are installed according to different stations, so that the working efficiency is greatly improved, the structure is simple and the operation is stable.