: As one of the promising thermal barrier coating (TBC) candidates, stoichiometric (La 0.8 Gd 0.2 ) 2 Ce 2 O 7 (LGC) coatings were prepared by atmospheric plasma spraying (APS), using (La 0.8 Gd 0.2 ) 2 Ce 2.5 O 8 as a spray powder and optimized spray parameters. It was found that spray distance and spray power both play an important role in the phase composition and microstructure of the coating. The LGC coating exhibited lower thermal conductivities than that of La 2 Ce 2 O 7 (LC) coating, which is ~0.67 W/m · K at 1200 ◦ C. Double-ceramic-layer (DCL) optimum (La 0.8 Gd 0.2 ) 2 Ce 2 O 7 /YSZ (LGC/YSZ) thermal barrier coating was prepared and its thermal shock behavior was investigated. The LGC/YSZ DCL TBCs had better thermal shock resistance ability than that of LC/YSZ TBCs, which was around 109 cycles at 1100 ◦ C. However, the failure mode was similar to that of LC/YSZ DCL TBCs, which was still layer-by-layer spallation in the top ceramic layer due to the sintering of the ceramic coating. The composition of the three above coatings were analyzed by ICP-OES. When (La 0.2 ) 2 Ce 2 O 7 , (La 0.8 Gd 0.2 ) 2 Ce 2.5 O 8 , and (La 0.8 Gd 0.2 ) 2 Ce 3 O 9 were sprayed under the same spray parameters, the (La + Gd)/Ce ratio in the as-sprayed coating was 0.78, 1.01, and 1.31, respectively. The results are listed in Figure 2, which shows the relationship of the (La + Gd)/Ce ratio between the coating and the powder. It was found that the (La + Gd)/Ce ratio in the coating increased with the increase of the (La + Gd)/Ce ratio in spray powder under the same spray parameters. When the powder of the (La + Gd)/Ce ratio was 0.8, the (La + Gd)/Ce ratio in the coating deposited was close to 1. Therefore, combined with XRD results, the feedstock powder with a nominal composition of (La 0.8 Gd 0.2 ) 2 Ce 2.5 O 8 can be selected to obtain the stoichiometric LGC coating.


It is known that the matrix predicates of emotion and evaluation subordinate sentential arguments not only with conjunction chto 'that': Obidno / plokho, chto komanda proigrala 'It's a shame / Too bad the team lost', but also with conjunctions kogda / esli 'when' / 'if': Plokho, kogda / esli komanda proigryvaet 'It's bad if the team loses'. The NRC data show that predicates of the other semantic classes that are not mentioned in grammars can also subordinate clauses with conjunctions kogda 'when' and esli 'if'. The article discusses examples of kogda-sentences with mental predicates (znat' 'to know', pomnit' 'to remember', ponimat' / poniatno 'to understand'): Ya pomnyu, kogda po Borodinskomu mostu khodili tramvai 'I remember when trams ran along the Borodino bridge'; Ponyatno, kogda kletki formiruyutsya v khode razvitiya zarodysha, no vo vzroslom organizme? 'It is clear when cells are formed during the development of the embryo, but in an adult organism?'


The relationships between the androgen receptors and cognitive processes in some brain regions such as hippocampus had been well documented in previous studies. The aim of this study was to evaluate the effect of bilateral intra-hippocampal infusion of modafinil on testosterone–induced spatial learning alterations in the Morris water maze (MWM) and also the evaluation of the quantity of BrdU-positive cells in dentate gyrus as a marker of cell proliferation. Bilateral intrahippocampal infusions (1 μL/side) with different doses of testosterone enanthate (10, 50, and 100 μg/side) or modafinil (50, 100, and 250 μM/side) were performed, 30 min prior to training in MWM for four repeated days in male rats. Control groups received dimethyl sulfoxide (DMSO). The behavioural findings of this study, showed considerable raises in time and distance of reaching the hidden platform in testosterone (100 μg/side) – treated animals, and also significant decreases in above mentioned parameters in modafinil (100 μM/side) – treated group compared to their related control groups. We also assessed the effects of modafinil (50, 100, and 250 μM/side) plus testosterone enanthate (100 μg/side), on the spatial learning in MWM and the effect on neurogenesis by recording BrdU-positive in all above mentioned groups. Final results of this study showed that modafinil (100 μM/side) prevented the testosterone (100 μg/side) – induced spatial learning deficits in MWM and also increased the quantity of BrdU-positive cells in dentate gyrus in combination evaluations in comparison with testosterone – treated animals.


ABSTRACT Our work on strawberry pollination started in 1996 because die top cultivar grown in France is 'Gariguette' and growers get good prices widi this cultivar very early in the season (March-April) as the quality of the product is well recognized. Crop management aimed at earliness (early covering, covering with a layer of non-woven fabric or under greenhouse polyethylene film, heating, etc.) induces the plant to flower under conditions unfavorable for pollination such as short days with low irradiation levels and temperatures around 8-10°C which hinder pollen formation. Such conditions often lead later on to problems in strawberry development and shape (large areas with unfertilized ovules, furrows, etc.). This is especially true for primary flowers, which should provide the largest strawberries. A preliminary study was first conducted to assess whether pollination was, indeed, a limiting factor for strawberry production in early crops and whether female reproductive structures also have played a role as well. When this work was completed and pollination was demonstrated as the main limiting factor for strawberry development from the first batch of flowers, the authors studied the different pollen vectors and quantified their action to determine their incidence in terms of production under "limiting" early cropping conditions.


This type of research is Research and Development (R&D) with the 4D development model (Define, Design, Development, and Disseminate). The research subjects were 70 Grade VII students of SMPN, NTB. The results of the Guided Inquiry-based E-Module feasibility test ranged from 89.56% to the very feasible category. This shows that the E-Module can be used as an instrument or learning media. Meanwhile, the results of the practicality test of the E-Module based on Guided Inquiry Learning based on student responses ranged from 88.32% in the very practical category, while the teacher's responses ranged from 93.04% to the very practical category. The test results for the effectiveness of using the Guided Inquiry-based E-Module are shown by the Gain-Score obtained by students after using the E-Module. This can be seen from the Gain score obtained by the experimental class ranging from 78.03% which indicates that the media is quite effective in learning. This can be seen from the Asymp value. Sig. (2-Tailed) ranges from 0.000 <0.05, meaning that there is a significant difference in the analytic abilities of students using guided inquiry learning-based E-Modules.


Abstract We show how two level atoms can be used to determine the local time dependent spectrum. The method is used in a one-dimensional cavity. The spectrum obtained is compared with the mode spectrum determined using spatially filtered second-order correlation functions. The spectra obtained using two level atoms give identical results with the mode spectrum. One benefit of the method is that only one time averages are needed. It is closely related to a realistic spectrum measurement.


In this paper corres ponding,by using the duality principle of geometric programming,we transformed the geometric programming problem into corres ponding duality programming problem,and using the property of geometric programming and duality programming,as well as the result of conjugate gradient method for non-linear programming,we integrated the two,and proposed a algorithm for unconstrained positive define geometric programming,in that a better generalized Armijo step search method is adopted.We proved the decent property and global convergence of the algorithm under weaker condition.


We analyse all the available Chandra observations of the Cartwheel galaxy and its compact group, taken between 2001 and 2008, with the main aim of addressing the variability in the X-ray band for this spectacular collisional ring galaxy. We focus on the study of point-like sources, in particular we are interested in ultraluminous X-ray sources (ULXs; LX ≥ 1039 erg s−1), that we treat as a class. We exploit archival XMM–Newton data to enrich the study of the long-term variability, on time-scales of months to years. We find a total of 44 sources in the group area, of which 37 in total are ULXs positionally linked with the galaxies and of which we can study variability. They are 29 in the Cartwheel itself, seven in G1, and one in G3. About one-third of these 37 sources show long-term variability, while no variability is detected within the single observations. Of those, five ULXs have a transient behaviour with a maximum range of variability (Lmax/Lmin) of about one order of magnitude and are the best candidate neutron stars. The X-ray luminosity function (XLF) of the point-like sources remains consistent in shape between the Chandra observations both for the Cartwheel galaxy itself and for G1, suggesting that flux variability does not strongly influence the average properties of the population on the observation time-scales.


Decision-making increasingly takes place under conditions of complexity and uncertainty. Social, economic, political, and environmental factors all need to be taken into consideration in decision-making and planning practices. In his recent book, Steen Leleur proposes systemic planning as a method for improving strategic decision-making. Leleur, an experienced transport planner, is Professor of decision support systems and planning at the Centre for Traffic and Transport at the Technical University of Denmark. His notion of systemic planning offers a holistic approach to decision-making. The book is divided into eight chapters. In the first chapter, Leleur introduces a systemic planning framework, comprising four interlinked levels: understanding complexity through different perspectives; designing a strategic planning learning process; specifying a toolbox for strategic planning; and applying systemic planning. The first level delineates a theoretical understanding of complexity. In Chapter 2, Niklas Luhmann's social systems theory is introduced. This theory provides an understanding of system complexity, based on the premise that a plurality of realities needs to be understood as different interpretations that create a system/ environment distinction. Chapter 3, then, discusses different 'ways of seeing' through epistemic lenses of complexity and simplicity, utilizing Morin's concept of constructive circularity. Chapter 4 outlines the second level of the framework, the learning process for systemic planning. Chapter 5 combines theory and practice in order to establish the third level, the toolbox for systemic planning. Based on the various paradigms of system theory, Leleur discerns five 'modes of inquiry' that inform systemic planning. Consideration of goals and viability, purpose, fairness, and diversity all inform systemic planning. Accounting for these aspects can further shed light on the complexity inherent in strategic decision-making. Seven 'hard' and seven 'soft' tools that inform strategic decision-making are then introduced. 'Hard' methods include cost–benefit analysis and risk analysis based on Monte Carlo simulation, while 'soft' methods include mind mapping, stakeholder analysis, and critical system theories. Chapter 6 examines which decision tools are most appropriate for each mode of inquiry, and for the various stages of the decision-making process (scanning, scoping, assessing, and choosing). The fourth level of the framework, the application of systemic planning, is covered in Chapters 7 and 8. Chapter 7 presents an example of systemic planning in practice, examining the relocation decision-making process of a Danish firm. Chapter 8 offers further examples of the application of systemic planning, Transport Reviews, Vol. 32, No. 6, 805–806, November 2012


A new universal one-chart smooth manifold model for vector information sources is introduced. Natural coordinates (a particular type of chart) for such data manifolds are then defined. Uniformly quantized natural coordinates form an optimal vector quantization code for a general vector source. Replicator neural networks (a specialized type of multilayer perceptron with three hidden layers) are the introduced. As properly configured examples of replicator networks approach minimum mean squared error (e.g., via training and architecture adjustment using randomly chosen vectors from the source), these networks automatically develop a mapping which, in the limit, produces natural coordinates for arbitrary source vectors. The new concept of removable noise (a noise model applicable to a wide variety of real-world noise processes) is then discussed. Replicator neural networks, when configured to approach minimum mean squared reconstruction error (e.g., via training and architecture adjustment on randomly chosen examples from a vector source, each with randomly chosen additive removable noise contamination), in the limit eliminate removable noise and produce natural coordinates for the data vector portions of the noise-corrupted source vectors. Consideration regarding selection of the dimension of a data manifold source model and the training/configuration of replicator neural networks are discussed.


Abstract: In situ imaging of small particles and biota in the water column is commonly used by scientists. Scrutinising such objects by imaging confronts system designers and researchers with a number of technical challenges. Here physical and technical aspects of optical subsea technologies are discussed, including parameters for the identification of suitable systems tailored to the specific scientific question at hand. The chapter tries to 'illuminate' why arbitrary combinations may not necessarily be ultimate guarantors for the required performance, points out common pitfalls, and provides an introduction to the necessary fundamentals of optics and design.


SCO5059, encoded in Streptomyces coelicolor A3(2), was identified as a polyphosphate glucokinase. The K m values of SCO5059 for glucose and polyphosphate (poly(P)6) were estimated to be 12 and 4 µM, respectively, and the k cat value was 0.3 s−1 at pH 7.7 at 28 °C. SCO5059 homologs are highly conserved among Streptomyces, and can work as polyphosphate glucokinase as well.


Kurt Lewin had it right: There is nothing so useful as a good theory. This is especially true for the study of emotional development. Why? Because after decades of conceptual blinders and blind alleys, research on emotional growth has emerged with new perspectives and fresh ideas about developmental change. But what is needed to thrust emotions to the center of developmental thinking is a theoretical view that provocatively integrates what is known and offers exciting new hypotheses. Where is the John Bowlby for emotion developmentalists? To understand the importance of the current moment, think back to what we thought we knew about emotional development not long ago. From the psychoanalytic heritage came the view that emotions develop through the prism of emergent intrapsychic realities, underscoring the fundamentally irrational and frequently disorganizing influences of emotions on behavioral competence. More recently, developmental study has been guided by structuralist accounts that portray emotions from the beginning as discrete, biologically organized constellations of expression, physiology, and subjectivity. Subsequent research has shown that emotions early in life are neither so disorganizing nor so wellorganized, and each account marginalized developmental analysis to the changes in appraisal, elicitation, or socialization that modify emotional experience while leaving untouched the fundamental nature of emotion itself. While taking the best of these earlier traditions (such as the emphasis on relational influences of the psychoanalytic tradition, and the structuralist concern with emotional communication), contemporary researchers have moved in more productive directions. Developmental study is guided by the view that emotions are biologically and psychologically adaptive, and that their development is important to social communication and social understanding as well as to psychological well-being. Functionalist thinking has provided a more open-ended definition of emotion (linked to individual goals) that offers new ways of thinking about emotional development, and has contributed to the explosion of research interest in emotion regulation and its association with competent functioning. Developmental research is also increasingly informed by biologically-oriented and genetically-informed research designs, studies of early risk for affective psychopathology, and the growth of emotion understanding in infancy and early childhood. But these advances do not constitute a coherent theory (for one thing, functionalist approaches still have difficulty answering "what is an emotion?"), even though they signal that the time is right for a useful one. Creating a new theory of emotional development is not for the faint-hearted. One reason is that the study of emotional development is breathtakingly integrative, entailing changes in developing neurobiology, temperamental individuality, relational influences, self-awareness and self-regulation, developing emotion knowledge, personality organization, considerations of emergent affective psychopathology, and the cultural construction of experience. What contemporary developmental theory is equal to this integrative challenge? Moreover, it appears likely that the story of emotional development will be complex and self-organizational (Thompson, Lewis, & Calkins, in press), involving mutually regulatory processes that dynamic systems approaches model but do not quite explain or predict. For a science oriented around linear growth models, this is a formidable conceptual challenge. In this light, Development of Emotions and Emotion Regulation is not the book we are seeking, but it takes us closer to the theory we need. The authors, Manfred Holodynski and Wolfgang Friedlmeier, set out to "formulate a theory that embeds the development of emotions and their regulation within their social and cultural context" (p. 6). Theirs is a life-


Variable β-SCF-CI calculation on the π-electronic transitions and π-electronic energies were performed over a number of possible tautomers of the purines and pyrimidines substituted with potential amino- or hydroxy-groups. The theoretical results, in particular on the monohydroxy-derivatives, were in good accord with the experimental informations about the preferable tautomers. On the whole, the theoretical data on the electronic transitions were fornd to be rather useful for classification of various tautomers into predominant and rare forms.


Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by the accumulation of amyloid plaques and neurofibrillary tangles in the brain. However, there are no peripheral biomarkers available that can detect AD onset. This study aimed to identify such AD biomarkers through an integrative analysis of blood cell gene expression data. We used two microarray datasets (GSE4226 and GSE4229) comparing blood cell transcriptomes of AD patients and matched controls to identify differentially expressed genes (DEGs). Geneset and protein overrepresentation analysis, protein-protein interaction (PPI), DEGs-Transcription Factor interactions, DEGs-MicroRNAs interactions, protein-drug interactions, and protein subcellular localizations analyses were performed on DEGs common to the datasets. We identified 25 common DEGs between the two datasets. Integration of genome scale transcriptome datasets with biomolecular networks revealed hub genes (TUBB, ATF3, NOL6, UQCRC1, SND1, CASP2, BTF3, INPP5K, VCAM1, and CSTF1), common transcription factors (FOXC1, ZNF3, GEMIN7, and SMG9) and miRNAs (mir-20a-5p, mir-93-5p, mir-16-5p, let-7b-5p, mir-708-5p, mir-24-3p, mir-26b-5p, mir-17-5p, mir-4270, and mir-4441). These included 8 previously identified AD markers (BTF3, VCAM, FOXC1, mir-26b-5p, mir-20a-5p, mir-93-5p, let-7b-5p, mir-24-3p) and 13 novel AD biomarkers. Evaluation of histone modification revealed that hub genes and transcription factors possess several histone modification sites associated with AD. Protein-drug interactions revealed 10 compounds that affect the identified AD candidate markers, including anti-neoplastic agents (Vinorelbine, Vincristine, Vinblastine, Epothilone D, Epothilone B, CYT997, and ZEN-012), a dermatological (Podofilox) and an immunosuppressive agent (Colchicine). The subcellular localization of markers varied, including nuclear, plasma membrane and cytosolic proteins. This study identified blood-cell derived molecular biomarker signatures that might be useful as peripheral biomarkers in AD. This study also identified drug and epigenetic data associated with these molecules that may be useful in designing therapeutic approaches to ameliorate AD.


Case studies Migration towards Yugoslavia Border crossing before 1990 Border crossing after 1990: diversification and informalisation of work contexts The Romanian-Serbian border as subject of recent political redefinition Migration towards Hungary Movement of people and goods before 1990 Movement of people and goods during transition Romanian-Hungarian Treaty and Hungarian Status Law: impacts on migration Migration towards Spain Migration from Jebel-Timis to Germany a village case study


Compositions useful for the selective removal of titanium nitride and/or photoresist etch residue materials relative to metal conducting, e.g., cobalt, ruthenium and copper, and insulating materials from a microelectronic device having same thereon. The removal compositions contain at least one oxidant and one etchant, may contain various corrosion inhibitors to ensure selectivity.


Members of the zinc cluster (or binuclear cluster) protein family are characterized by a Zn(II)Cys6 zinc finger involved in DNA recognition and binding. These fungal proteins are transcriptional regulators of genes involved in a wide variety of cellular processes. One member, Gal4p, is involved in galactose metabolism, while others play a major role in primary and secondary metabolism, control of meiosis, and multidrug resistance. Sequencing of the Saccharomyces cerevisiae genome has revealed that 55 genes encoding putative zinc cluster proteins are present in budding yeast. However, the roles of many of these zinc cluster proteins are unknown. In order to better understand their functions, we have performed a phenotypic analysis of these putative zinc cluster proteins. We have implicated a number of them in a variety of processes in the cell, including multidrug resistance. Stb5p has been shown to be a major player in regulating the expression of multidrug resistance genes. Other zinc cluster activators of multidrug resistance genes include Pdr1p, Pdr3p, and Yrr1p. These regulators of multidrug resistance appear to interact with each other, forming many different sub-populations of homo- and heterodimers. Stb5p is found predominantly as a heterodimer with Pdr1p. It also appears that Pdr1p is a master regulator able to interact with many different partners, enabling it to mediate control over multidrug resistance genes.


The purpose of this study is to investigate the effect of Strategic Reading, specifically the Collaborative Strategic Reading (CSR) on Taif University. The participants are students from classes of English at the Department of Foreign Languages, of Arts College. The data mainly came from statistical results, including the questionnaire responses. The findings of CSR will be explored to find out the effect, positive or negative on the Taif university learners' reading comprehension particularly in relation to the comprehension questions on getting the main idea and finding the supporting details. The findings of the study will be used to suggest implementing better comprehension strategy instruction for the learners to adopt some degree of strategic reading behaviours, and to take long-term efforts and practices for EFL learners to fully develop their strategic reading abilities. The present paper is an effort to deliver a base for better understanding the relationship between reading comprehension and reading strategies. The results of this paper will be implemented for better reading strategy instruction at Taif University, KSA.


This paper surveys the pros and cons of Central Bank Independence and how it could help set developing economies on the path of steady growth. The research develops a theoretical framework for the analysis of central bank independence in budding democracies. The recent trend in Macro- Economic management has resulted in separation of powers between monetary and fiscal authorities with the resultant effect that governments are supposedly held in check regarding their borrowing and spending potential. Can this check be standardized and replicated in emerging democracies where the true values of democracy is yet to be felt or can Central Banks indeed say no to political pressure?


The article highlights the experience of the program development and technological map designing for Bachelors of Social Work educational practice within the requirements of the FSES for Higher Professional Training and for major "social work in the system of social services" in particular. There defined goals and objectives of the practice, its content and projected results of modules mastering are revealed, the main students activities are characterized and the criteria for assessing their personal and professional achievements are provided in this paper.


The use of hydrofluoroether liquid wetted wipes for the decontamination of sensitive equipment is attracting great interest. Contacting the contaminated equipment with such wipes results in the rap...


This paper deals with the issue of financial literacy as one of the professional competencies of social workers to prevent or solve socio-economic problems of clients. A practical example is presented of resolving the financial problems of a client of a non-profit  social  organization,  a homeless  shelter  in  the Czech Republic. Through knowledge and experience in financial literacy issues, the educated social worker is able to determine the extent and causes of material need persuade the client to cooperate, as well as mobilize him toward alleviating or eliminating his unfavorable financial situation. Original Article 70 Clinical Social Work and Health Intervention Clinical Social Work and Health Intervention Vol. 12 No. 1 202


This paper reviews the implications of the concept of nation and nationality in the Society of Information as well as some fundamental questions which arise from our relationship with new technologies: Which are the new forms of human relations appearing in the net? Which new identities do these new electronic devices generate? How is everything articulated within the global, the regional, the national and the communitarian?


The paper considers peculiarities of the Russian model of Arctic economy; the up-to-date state, urgent problems and near-term outlook of the Arctic transport system development have been revealed.


It is shown in this work that FMOC amino acid chlorides are also applicable to solid-phase syntheses by the simple expedient of in situ conversion to the appropriate N-hydroxybenzotriazole ester via reaction with a 1:1 mixture of HOBt and an appropriate tertiary amine. In cases where acid chlorides are inaccessible due to side-chain incompatibility, pentafluorophenyl esters or BOP-induced couplings represent convenient spot substitutes


The simplicity of the state dependence at relatively high temperatures ofthe many-body potential contribution to the pressure and energy has been pointed out previously (J. Ram and P. A. Egelstaff, J. Phys. Chem. Liq. 14, 29 (1984); A. Teitsima and P. A. Egelstaff, Phys. Rev. A 21, 367 (1980)). In this paper, we investigate how far these many-body potential terms may be represented by simple models in the case of krypton on the 423-, 273-, 190-, and 150-K isotherms, and xenon on the 170-, 210-, and 270-K isotherms. At the higher temperatures the best agreement is found for the mean-field type of theory, and some consequences are pointed out. On the lower isotherms a state point is found where the many-body energy vanishes, and large departures from mean-field behavior are observed. This is attributed to the influence of short-ranged many-body forces.


The puzzle of 3D magnetic interactions in the structurally 2D layered oxide Na$_{x}$CoO$_2$ is addressed using first principles calculations and analysis of the exchange mechanisms. The calculations agree with recent neutron results, favoring AFM stacking of FM planes. Superexchange via direct O-O hopping and through intermediate Na $sp^2$ hybrids couples each Co to its nearest and six \textit{next}-nearest interplanar neighbors equally. The individual exchange constants are rather 2D, like the lattice itself, but due to multiple c-axis exchange paths, the magnetism becomes effectively 3D.


Self‐Reporting Biosensors In article number 2105285, John R. Mercer and co‐workers develop an implantable miniaturised sensor and telemetry system that can detect and discern different cell types associated with in stent restenosis, distinguish sub‐plaque components and differentiate blood from blood clot. This work shows that microfabricated sensors can be used for both stent and grafts implantables to provide clinically actionable data.


This evaluation was conducted on behalf of the Federal Ministry for Climate Action, Environment, Energy, Mobility, Innovation and Technology (BMK) and examines the programme Research Partnerships – Industrial PhD with regard to its concept, implementation, achievement of objectives and impacts. Based on the results of this analysis, the evaluators draw conclusions for the further development of the programme. The evaluation covers the period from 2014 to mid-2020. The methodological basis of the evaluation is a document analysis, a secondary data analysis of the FFG project monitoring data, expert interviews, an online survey of funding recipients and a workshop.


At the present time, various English songs are existed which cannot be understood by citizens who do not exploit that language as the ways of communication in their daily life. Therefore, transaltion shift is needed to get a better translation. Translator must produce many shifts to keep a translated version as nicely rhyming as the source language. Basically, there are four main types of shifts, namely: structure shift, class shift, unit shift, and intra-system shift.
This research focused on the unit/rank shift in Walt Disney Songs of "Frozen" movie. The purposes can be stated as finding out: (1) kinds of rank at unit shift used by the translator in translating Walt Disney songs of "Frozen" movie into Indonesian; and (2) the most dominant rank used by the translator in translating Walt Disney songs of "Frozen" movie into Indonesian.
This research was conducted by means descriptive research design. The data were obtained from two songs of "Frozen" movie in English entitled (1) Let it Go, (2) For the First Time in Forever, and in Indonesian translation entitled (1) Lepaskan, (2) Untuk Pertama Kalinya. This reseach contained all kinds of unit shift, covering upward rank shift and downward rank shift.
Based on the data analysis, the researcher found 2 (two) kinds of rank at unit shift. They were upward rank shift and downward rank shift. The researcher found 39 shifts in "Let it Go" which consists of 6 upward rank shifts and 33 downward rank shifts. She also found 21 shifts in "For The First Time In Forever" which consists of 8 upward rank shifts and 13 downward rank shifts. Furthermore, downward rank shift occurs as the highest frequency and 46 (forty six) items out of 60 (sixty seven) items or 76,6%.


The Atlas of Living Australia (ALA) has developed a software platform since 2009. This open source platform was initially developed by the ALA team in Canberra. The platform is now in use in several other countries as part of the Living Atlases community with support from GBIF. The architecture is a microservices based architecture. As such, it consists of multiple components that communicate through the ALA's web services. This presentation will include a general overview of ALA components. It will cover some of the technologies used and the overall design and philosophy behind the system.


It tries to understand the cooperative structure evolution of innovation policymakers,through a quantitative analysis of 287 policies issued by China's central government institutions from 1980 to 2005 and of 79 policies introduced from 2006 to 2008 to implement "The Medium and Long-Term Plan for the Development of Science and Technology(MLP)(2006—2020)".The result shows that,with the change of innovation strategic scene,there has been a gradual departure from the pattern in which innovation policies are formulated by one single government institution;there are more systematic and consistent cooperation under the process of making policy;the harmony is enhancing between institutions.


Human-driven global warming is critically affecting the hydrological cycle, ecosystems, and economies globally. Despite advancements in predicting Earth's climate response to elevated CO2 levels, refining climate models to reduce uncertainties remains imperative. Limited high-quality continental sedimentary archives result in a bias toward marine and higher latitude settings, but the sediments below long-lived lakes are excellent archives of past climatic and ecological variability. This thesis centers on Lake Chala in easternmost equatorial Africa, ideally located to record the climate history of this region fully dependent on Indian Ocean moisture. The International Continental Drilling Program (ICDP) project DeepCHALLA recovered a continuous core sequence of organic-rich laminated sediments from the lake bottom spanning the last ~250,000 years (250 kyr). These sediments contain ample amounts of glycerol dialkyl glycerol tetraethers (GDGTs) and glycerol monoalkyl glycerol tetraethers (GMGTs), groups of microbial membrane lipids which are useful for paleoclimate research. However, uncertainties surrounding GDGT/GMGT-based climate proxies, including their biological sources and potential biases, complicate their application.
Part 1 of this thesis focuses on GDGT/GMGT proxy validation in contemporary settings. Settling particles, suspended particulate matter, surface sediments, and catchment soils from Lake Chala are analyzed to trace biomarker origins and dynamics. For example, the so-called "BIT index" is validated as an effective moisture balance proxy for Lake Chala, and the functioning of the popular TEX86 palaeothermometry is also assessed. New temperature proxies based on branched GMGTs in East African lake sediments and detailed analysis of the origin and drivers of these lipids in the modern lake are presented. Importantly, these modern studies support that a temperature model based on branched GDGTs in globally distributed lake surface sediments is the most appropriate choice for the Lake Chala sediments.
Part 2 of this thesis investigates the stability of the present-day climate-proxy relationships throughout Lake Chala's 250-kyr history. GDGT concentrations and proxies are compared to independent data for lake dynamics and chemistry (diatoms, seismic data and lithology). Altogether, this data suggests that during the earliest depositional phases (i.e., before ~160 ka), the degree of water column stratification was not comparable to the modern-system, resulting in weaker relationships between the GDGTs/GMGTs and regional climate variability and hindering extrapolation of the inferred climate-proxy relationships throughout the full sequence. The biomarker proxies provide trustworthy records for temperature and moisture balance back to ~160 ka.

Finally in Part 3, the records of temperature and hydrological variability for equatorial East Africa, encompassing the entire last interglacial and glacial periods, are presented and their implications for past a future climate dynamics in the region are discussed. For example, these records facilitate new discussion surrounding the causes of the so-called "African Megdaroughts" in tropical Africa during the last interglacial, and reveal and important climatic tipping point ~11.7 ka between temperature and regional hydrology which is relevant for present and future climate in this region.
This study underscores the importance of climate proxies validation. It reveals Lake Chala's potential as a reference point for Quaternary paleoclimate in the tropics, contributing to a deeper comprehension of Earth's climate evolution.


For the investigated indolamines, the recovery following extraction with n-butanol and acetic acid ethyl ester from alkaline solution amounted to 80-90%. Using benzene only the two 5-methoxyindolamines were transferred from the alkaline medium into the organic phase. The reaction of the o-phthaldialdehyde with substituted indolamines was optimized in regard to higher fluorimetric detection sensitivity. The lower limit of determination was 2.0 ng for 5HT and 5OHDMT, and 1.0 ng for 5MeOT and 5MeODMT.


This medieval adage might well be applied to the children of the poor in the United States-to the children of sharecroppers and farm laborers who have been forced off the land by farm machines, to the children of unskilled laborers in cities, to the sons and daughters of unlettered parents everywhere. Despite the disadvantages of an impoverished cultural and economic background, these boys and girls must try to make their way in a society that is becoming more literate and more technical.


A study was conducted to evaluate the effect of feed cycling on specific growth rate, condition factor and RNA/DNA ratio of Labeo rohita. Fingerling L. rohita were randomly collected from Qadria Fish Farm and Hatchery, Multan, Pakistan and divided into control, 5 days and 10 days feed cycling groups. Specific growth rate (% g day-1), body composition, condition factor, and RNA/DNA ratio of individual fish and of each group were calculated. There was a highly significant (P<0.001) effect of feed cycling on specific growth rate and RNA/DNA ratio of L. rohita. However, the effect on condition factor was non-significant. A gradual decline was observed in specific growth rate and RNA/DNA ratio with increasing length of starvation. L. rohita was able to maintain its main body constituents such as fat, protein, organic and inorganic contents indicating a compensatory growth, which was independent of duration of starvation


When grinding the surface of military or precise bearings,accuracy degree of M7475B surface-gringding machine cann't meet its processing demands.Some methods in improving precision and maintenance were put for- ward on the basis of testing analyzing and adjusting the construction and precision of the machine,the effectiveness was also good.


This work proposes an invariant descriptor and a pipeline for the registration of surface range images based on segmentation/reconstruction making use of an edge detection technique combined with a clustering technique using mesh decimation. This novel descriptor is applied to contours and it is invariant to similarity transformations including rotation, translation, uniform scale and it is robust to noise. The proposed feature descriptor makes use of corresponding points extracted from two images and a signature label is assigned specifically to a point considering the geometrical distribution of its neighbourhood, reducing possible areas of overlapping and the ambiguity in the search process. The descriptor was evaluated through a series of tests with various object range images. To validate the candidate transformations, the fitting errors between the two range images are evaluated by the iterative closest point algorithm. This study also presents and discusses results from the application of the developed pipeline in a vision sensor mounted on a robot arm specially built as part of a R&D project to acquire range images by laser scanning over the surface of hydraulic turbine blades. The sensor generates 3D surface models to be registered in the 3D coordinate system of the robot controller.


Materials with tunable long persistent luminescence (LPL) properties have wide applications in security signs, anti-counterfeiting, data encrypting and other fields, which have attracted great attention. However, the majority of reported tunable LPL materials are pure organic molecules or polymers. Herein, a series of metal-organic coordination polymers displaying color-tunable LPL were synthesized by the self-assembly of HTzPTpy ligand with different cadmium halides (X = Cl, Br, and I). In solid state, their LPL emission colors can be tuned by the time-evolution, as well as excitation and temperature variation, realizing multi-mode dynamic color tuning from green to yellow or green to red, and representing the first example in single component coordination polymer materials. Single-crystal X-ray diffraction analysis and theoretical calculations reveal that the modification of LPL is due to the balanced action from single molecule and aggregate triplet excited states aroused by external heavy-atom effect. The results suggest that the rational introduction of different halide anions into coordination polymers to realize multi-color LPL is promising for different domain applications, including imaging, anti-counterfeiting and security protection.


In vitro brain slice preparations are instrumental in developing our understanding of the nervous system. However, the current lifespan of an acute brain slice is limited to approximately 6-12 hours. This reduces potential experimentation time and leads to considerable waste of neural tissue. We have designed, developed and tested a novel incubation system capable of extending the lifespan of these brain slices. This is done by controlling the temperature and pH of the artificial cerebral spinal fluid in which the slices are incubated while continuously passing the fluid through a UVC filtration system. This system is capable of maintaining extremely low bacterial levels and significantly extending the brain slice lifespan to at least 24 hours. Brain slice viability was validated through electrophysiological recordings as well as live/dead cell assays.


: New details of F-actin organisation in leaf epidermal and stomatal cells were revealed by rhodamine — and fluorescein — phalloidin staining of fixed epidermal peels of Tradescantia virginiana and visualisation by confocal microscopy. Non-specialised epidermal cells contain highly organised arrays of fine cortical actin filaments aligned in transverse or oblique orientations. In interphase guard mother cells (GMCs), the arrangement of cortical F-actin changes on the periclinal and anticlinal cell walls at different times during differentiation. Initially, cortical F-actin on the periclinal surfaces is oriented transversely and F-actin is evenly distributed around the anticlinal walls. Following polarisation of the adjacent subsidiary mother cells (SMCs), actin in GMCs concentrates on the lateral anticlinal walls, but not on the transverse walls. Subsequently, F-actin on the periclinal walls reorients to radial and then longitudinal. Organisation of F-actin in SMCs appears to be influenced by the adjacent GMCs and co-ordination in F-actin arrangements in cells of the stomatal complex continues through to the formation of the guard cell pair. Our studies indicate that actin bands marking the division site in prophase cells, and detected in microinjected living material, are a particularly labile subset of F-actin. Actin bands were difficult to preserve, even when aldehyde fixation was avoided, in contrast to all interphase and mitotic F-actin.


The purpose of this paper is the identification of determinants, and the assessment of their influence, of the decision to innovate in Turkish manufacturing firms, with an emphasis on the impact of trade liberalization. A binomial logit model is used to assess the influence of explanatory variables on the probability that firms will innovate. Size, market structure, and profitability exert a positive impact on that probability. Competition on international markets, international technology transfers, skill level of the workforce, a lower degree of vertical integration, and price level all have a positive influence. Competition on domestic markets, acquisition of technology licenses by local firms, and foreign direct investment do not exert a statistically significant effect on the innovation decisions of firms.


Autonomous systems are currently trending with the radar taking a major role. Due to the advantages like compact sizes and having high performance, radars are used in advanced driver assistance systems (ADAS) such as the adaptive cruise control (ACC). Since passenger safety has a high priority, it is necessary to detect and classify targets in the near-field environment of the vehicle. Existing approaches use methods such as data fusion with additional sensors. This paper describes a classification process of moving targets using a dual automotive radar system and convolutional neural networks (CNN). Due to the detailed resolution of the radar and the great adaptability of the CNN a high classification probability has been achieved in first measurement trials.


Here we report a case of co-infection of hydatid cyst with invasive apergillosis, in a previously healthy, non immunocom- promised, 26 year old man. Chest x-ray revealed a large cystic cavity in left upper lobe of lung histopathologic examination of the specimen confirmed the diagnosis of hydatid cyst with numerous fungal hyphea which invaded the laminated wall of the cyst. Although, co-infection with hydatid cyst is very rare finding but, in this patient hydatid cyst caused a new cavity formation which is the most common predisposing factor for development of aspergilloma, so we should consider aspergil- losis infection in every lung cavity formation.


Conceptual fundamentals of making up of professional competence of military specialists are systematised: factors, measure, frame of professional qualities, etc.


In this article,the oxidation-fibroin peptide anti-pilling treatment was used on cashmere knitting fabric because of particular superficial structure of cashmere fiber,and the optimal technology was obtained by orthogonal experiment.The optimal technologies were concentration of oxidation 40 ml/L,pH Value 7,50 ℃,50 min,concentration of sodium pyrophosphate 6 g/L,concentration of fibroin peptide 6%(owf),pH Value 9,40 ℃,30 min.The improved anti-pilling effect was showed on the cashmere knitting fabric which was treated with oxidation-fibroin peptide.


Objectives : This in vitro research was conducted to investigate the effect of the Ginseng Radix plus Crataegi Fructus. on the cytokine protein release and Nitric oxide release in releted to Alzheimer's disease. Methods : Specifically, the effects of the Ginseng Radix plus Crataegi Fructus extract on , IL-6, of BV2 microglia cell line treated with lipopolysacchride. Results: The Ginseng Radix plus Crataegi Fructus extract suppressed the production of inflammatory cytokine protein , IL-6, and in BV2 microglia cell line treated with lipopolysacchride. Conclusion: These results suggest that the Ginseng Radix plus Crataegi Fructus extract may be effective for the prevention and treatment of Alzheimer's disease. Investigation into the clinical use of the Gin-CHF extract for Alzheimer's disease is suggested for future research.


The utility model discloses a splice-type LED (Light Emitting Diode) illuminating light fitting and a connecting piece thereof. The illuminating light fitting comprises a light fitting housing and a light source module strip mounted on the light fitting housing, wherein the light source module strip comprises an LED light source and a light source mounting base; the light fitting housing is formed by splicing a plurality of arch structures side by side; two adjacent arch structures are spliced by the connecting piece; the light source mounting base, the connecting piece and the light fitting housing are all long strip-shaped stretching profiles; both opposite sides of the stretching direction of the connecting piece are provided with slots respectively for insertion of the light source mounting base and the lower end of the arch structure; and the slots are obliquely arranged. The LED illuminating light fitting provided by the utility model has the advantages that through the connecting piece with specific structure, a large light fitting can be formed by splicing, and the mounting and dismounting are simple and convenient.


Collaboration among the National Highway Traffic Safety Administration (NHTSA), an independent automobile research company (Calspan) and the Chrysler Corp. has produced an ultra-safe, fuel-efficient and very practical car. Called the Calspan-Chrysler RSV (Research Safety Vehicle), the five-passenger hatchback only weighs 2651 lb (1203 kg). This car is based on Chrysler's Simca 1306 which has been restructured to permit a safe front barrier collision at 50 mph (850 kmh) and safe car-to-car impacts of 45 mph (72 kmh) on the side and 50 mph (80 kmh) in the rear. It also has an "inflatabelt" restraint system, new run-flat tires, a special soft front end designed for pedestrian protection, transverse front-wheel-drive and other safety features, including see-through head restraints. The new run-flat tires contain a plastic ring which clamps around the wheel and permits the tire to run for 50 mi (80 km) at up to 50 mph (80 kmh). Rubber-like front and rear ends on the car protect it from a 6 mph (9.6 kmh) front end barrier impact and 2 one-half mph (4.0 kmh) rear barrier collision. This RSV is powered by a 85.4 cu-in. (1.4 l) four-cylinder engine that provides a combined city-highway mileage of 30 mpg (12.8 kml).


Twenty-five neonates receiving intensive care were monitored to determine the value of near-infrared spectroscopy (NIRS) for bedside assessment of cerebral oxygenation. NIRS gives a real-time measure of changes in oxyhemoglobin, deoxyhemoglobin, blood volume, and cytochrome aa/sub 3/. Periods of cerebral oxygen insufficiency unassessed by standard monitoring techniques were detected, and rapid changes were observed in cerebral oxygenation in response to different care procedures and therapies. Most importantly, this technique provides an opportunity to study neonatal physiology and the pathophysiology of disease processes.<<ETX>>


Objective:To study the expression of hepatocyte growth factor(HGF) during the progression of renal interstitial fibrosis in rat unilateral ureteral obstruction(UUO) model and the effect of Shenfu injection.Methods:The obstructive nephropathy model was established by unilateral ureteral obstruction(UUO),fifty-six rats were randomly assigned into sham group,operation group(UUO group) and treatment group(UUO+shenfu).At 7th and 14th day,renal function and histopathological changes were evaluated.The expression of HGF in renal tissue was examined by immunohistochemistry.Results:In comparison with the sham group,the renal interstitial fibrosis was obvious and the expression of HGF significantly increased(P0.05) in UUO group.In comparison with the UUO group,the degree of interstitial fibrosis was significantly ameliorated and the expression of HGF significantly increased at 7th day(P0.05) and at 14th day(P0.05).Conclusion:Shenfu injection may protect the kidney by up-regulating the expression of HGF in the progression of renal interstitial fibrosis.


FIELD: chemistry. SUBSTANCE: invention relates to a biodegradable plastic having increased biodegradation speed. Said biodegradable plastic having increased biodegradation speed is characterised by that it comprises: (a) approximately 0.1 to 40 wt% of finely distributed particles of a biodegradable, water-soluble, organic component with a mean particle size of less than 10 mcm, wherein said water-soluble component is a component based on water-soluble saccharide, which is saccharose, glucose, maltose and/or lactose, and (b) finely distributed particles of a water-soluble, inorganic component containing N, P and/or S, promoting growth of microorganisms and with a mean particle size of less than 10 mcm. Also disclosed is use plastic for producing threads or for producing film. EFFECT: technical result is high biodegradability. 17 cl, 1 tbl, 1 ex


Caught in the act: N-Heterocyclic carbene copper(I) complexes (1; IPr=1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene) serve as an excellent catalyst for the carboxylation of alkylboranes (2; R=alkyl) with CO(2) to afford a variety of functionalized carboxylic acids (3) in high yields. A novel copper methoxide/alkylborane adduct (A) and its subsequent CO(2) insertion product (B) have been isolated and shown to be true active catalyst species.


The IJS was an initiative of the judiciary at a time when many members of the public and the profession took the view that newly appointed judicial officers went to the bench fully equipped with the skills they needed. The judiciary responsibly indicated that this was not the case and set up a permanent resource for judges recognising that professional development was a significant element in judicial performance. 2


Photodetectors based on two-dimensional (2D) materials have attracted considerable attention because of their unique properties. To further improve the performance of self-driven photodetectors based on van der Waals heterojunctions, a conductive band minimum (CBM) matched self-driven SnS2/WS2 van der Waals heterojunction photodetector based on a SiO2/Si substrate has been designed. The device exhibits a positive current at zero voltage under 365 nm laser illumination. This is attributed to the built-in electric field at the interface of the SnS2 and WS2 layer, which will separate and transport the photogenerated carriers, even at zero bias voltage. In addition, the Al2O3 layer is covered by the surface of the SnS2/WS2 photodetector to further improve the performance, because the Al2O3 layer will introduce tensile stress on the surface of the 2D materials leading to a higher electron concentration and smaller effective mass of electrons in the films. This work provides an idea for the research of self-driven photodetectors based on a van der Waals heterogeneous junction.


&NA; The recently described modification of the osmium tetroxide method for demonstrating lipid1 can be used on liver biopsies taken for diagnostic purposes. An unstained section is used for the quantitation of lipid and sequential sections can be stained by all the 'routine' liver stains.


The analysis is about the education situation of that time in the United States,as well as on the base of lifelong education thoughts R.M.Hutchins,who is one of American famous educationalist,puts forward the concept and the thoughts of learning society.He thinks that the learning should overstep the wall of school and everyone must to be learning without intermission.The thoughts of Hutchins'learning society have an important implication for current adult education.


Next generation wireless networks are expected to be heterogeneous consisting of several wireless technologies including, but not limited to, UMTS, GPRS, Satellite and WLAN networks. These networks provide bandwidths that range from tenth hundreds of Kbits/sec provided by technologies such as GPRS, to tens of Mbits/sec provided by Broadband wireless LANs such 802.11a. Here we study the problem of resource allocations in heterogeneous wireless networks, where the demand for bandwidth is growing at an enormous rate. Wireless networks may cooperate either because they can not deal with resource allocation demands alone or because they can reduce their cost by working together. We formulate our approach as an optimization problem that allocates resources to mobile users and maximizes benefits for networks. In addition, we employ an exponential cost function to balance load across multiple heterogeneous networks. A resource allocation model made of the three wireless networks and a user is presented. Cooperative game-theory concepts are used to identify stable resource allocations, under which all three networks find it beneficial to cooperate. The results suggest that an allocation that maximizes revenues exists, which makes this cooperation attractive to all networks.


In the Transcendental Aesthetics, Kant introduces the distinction between intuitions and concepts. Intuitions are immediate and singular representations. Concepts are mediate and universal representations. In the Transcendental Logic, Kant defines the concept as a function or rule. The concept is a rule of unity of the multiplicity of intuition. This investigation aims to show that there is a tension between the definition of concept in the Aesthetics and the Dialectic with the notion of concept as function, according to its presentation in the Transcendental Logic. Our hypothesis is that the definition of concept as a function that is introduced in the Transcendental Logic is grounded on a sui generis notion of concept that comes into tension with the definition of concept as a representation by common marks.


The article presents the simulation results of electromagnetic effects of a 25 kV electric traction network on a steel pipeline with a pipe diameter of 250 mm. It is shown that a pipeline with insulating pipe coatings can induce stresses dangerous to operating personnel. At certain points of the pipeline, grounded on both sides, the magnitude of the induced voltage can reach 116 V with an approach width of 100 meters. Therefore, it is required to develop and implement special measures to protect operating personnel. With an increase in the approach width to 400 m, the maximum values of the induced voltages did not exceed the permissible level. In modes of short circuits in the electric traction network, the induced voltages in the pipeline may briefly exceed 500 V. The highest voltages are observed at points located near the short circuit point. In case of short circuits at the terminals of the traction substations, the magnitudes of the induced voltages are reduced to 75 V. To reduce the induced voltages, the following measures can be assumed: reducing the length of parallel passage sections of pipeline and railway, increasing the approach width, installing additional groundings. During the operation of the structure, the magnitude of the "pipe-to-ground" transition resistance may decrease, which will result in a decrease in induced voltages.


The behavior of energy E(t) is studied for a class of reaction diffusion equation ut = f(u)+ϵΔu; here ϵ > 0. The asymptotic behavior of the energy is of particular interest to indicate singularity formation in the solution in the long run. While for sufficiently large diffusion coefficient ϵ > 0, decay of energy is expected, small ϵ or the limiting ϵ = 0, show some interesting behavior which is related to the singularity formation of solutions in the long run. From the numerical experiments we observe that energy may tend to a non trivial asymptotic, and in some cases it may grow unboundedly.


The romanopendata.eu portal is the culmination of the knowledge representation efforts conducted during the "EPNet: Production and distribution of food during the Roman Empire" project. The aim of the portal is to allow access to the project's epigraphic data on Roman amphorae to both the project members and the community in a standard and interoperable way. To this end, it provides two main interfaces. The core interface is a virtual knowledge graph, which is presented in RDF, conforms to an ontology, and is queryable through a SPARQL endpoint. The second interface is a visual query system, built on top of the SPARQL endpoint, that allows non-technical users to explore the data without having to worry about writing queries.


The aim of this study is to propose a novel flexible dry electrode and assembly to a wearable single-lead ECG patch for continuously monitoring atrial fibrillation (AF) in a real-life scenario. Silver ink was screen-printed on a flexible polyurethane substrate to fabricate the multilayered dry electrode. A wearable recording patch with three dry electrodes was developed to collect single-lead ECG signal, particularly to provide a robust anti-artifact capability by employing a driven right leg electrode as reference. The characterization of the dry electrode based patch was quantified by combing the engineering measurement on raw signal quality and the clinical evaluation of automatical AF detection. A total of 50 patients (age 70 ± 11) were enrolled. Each patient wore one or two patches and a standard Holter simultaneously for a continuous 24 hours ECG recording in a real-life scenario. The averaged R wave peak amplitude, signal-to-noise ratio, and signal-to-artifact ratio were 0.75–1.47 mV, 3–6 dB, and 3–7, respectively. Compared with two different cardiologists' interpretations of the ECGs from dry electrodes, an offline detection algorithm automatically interpreted AF with the overall accuracy 93.57% and 85.94% during the stationary and movement states, respectively. The obtained results demonstrated the ability of using a flexible screen-printed dry electrode and assembly to a wearable patch to effectively record ECG signal in patients even disturbed by body motions, which may establish its clinical validity and applicability.


The paper considers approaches to optimization of known designs of traditional rolling stock beam. The authors have studied a classic case of loading a console with force. They have gained values of stress and full deformations for a console with a rectangular cross-section. The authors have studied a possibility to optimize design by means of decrease of mass and prevention of actual stress above the limit of material fluidity (local stress hasn't been considered). On the basis of analysis of gained results they have proposed a more rational profile of a console - its construction is optimized along a horizontal transverse axis. Verification of stress and deformations of the optimized model have been carried out in a calculation module, Results show a significant improvement of workability of the optimized console design that differs in reduced mass without losing in strength and rigidity.


There are controversial data about of the most suitable method of delivery for the infants with pre- and ante-natal diagnosis of gastroschisis . The objective of the present study is to investigate the role of the gestational age and mode of delivery on the outcomes of infants with gastroschisis . Twenty seven infants diagnosed with gastroschisis were included in the current study . The study was conducted at Al-Zahra Teaching Hospital in Al-Najaf city, in Iraq , during the period between October 2017 to October 2020 . The results of the current study show that there is a significant relationship between each of mode of delivery and gestational age with type of surgery (p value = 0.04) . It also shows a high significant relationship between gestational age and age at presentation (p value = 0.01) . The study concluded that the outcome of newborn with gastroschisis might be slightly affected by timing and mode of delivery .


The relationship between social insurance, which provides families protection against certain risks, and child economic security is understudied. Using the 2004 Survey of Income and Program Participation (SIPP) matched to Social Security Administration benefit records, this article investigates the economic welfare effects of the child component of the US Social Security program. We examine how the poverty rate of child beneficiaries would change, absent Social Security income, and how heavily the family incomes of these children rely on it, by family characteristics. Our findings reveal that Social Security plays an important role in mitigating economic insecurity among children deprived of a wage-earning parent through disability, death, or retirement. Family structure, earnings, and employment status are identified as key factors moderating the effect of Social Security on child recipients' financial circumstance.


"American citizens are not protected by a law akin to the British firearms Act 1920. These regulations, along with the laws passed in 1936, 1968, and 1988, have protected British citizens for nearly three generations. Quite apart from America, "where buying a handgun is as easy as buying a tooth brush," British society is far more circumspect about private weaponry. To obtain a gun license, potential owners must satisfy local police that they have "good reason" for possessing a gun and that they are "fit to be entrusted with it." One of the guiding philosophies behind British gun restrictions—that personal protection is not a good reason for having a firearm—may seem untenable (possibly quaint) to some Americans. Yet defenseless Britons remain comparatively safe in their homes with a murder rate one tenth of that in the USA.


Sampling for arc-fault detection, ground-fault detection, and grounded-neutral fault detection uses a single analog-to-digital converter (ADC). The arc-fault and ground-fault sampling occurs at regular sampling periods that are relatively short compared to the time between them, thus allowing grounded-neutral fault sampling to occur before and/or after one of these sampling periods. A predefined event may be used to ensure the grounded-neutral fault sampling occurs immediately before and/or after one of the periodic sampling periods. The predefined event may be the expiration of a timer or the time for a sinusoidal signal in a ground fault sense circuit to make a predefined number of zero-crossings. This avoids interference between the arc-fault sampling, the ground-fault sampling and grounded-neutral fault sampling, allowing a single ADC to perform all samplings concurrently. The timing of the predefined event may be periodically reset to compensate for any changes due to temperature and/or over time.


We investigate nonperturbatively the effect of a magnetic dopant impurity on the edge transport of a quantum spin Hall (QSH) insulator. We show that for a strongly coupled magnetic dopant located near the edge of a system, a pair of transmission anti-resonances appear. When the chemical potential is on resonance, interaction effects broaden the anti-resonance width with decreasing temperature, thus suppressing transport for both repulsive and moderately attractive interactions. Consequences for the recently observed QSH insulating phase of the $1$-T$^{\prime}$ of WTe$_2$ are briefly discussed.


Evaluation of e-government systems is difficult duty since it involves many perspectives that complicate enumerating its benefits. Although the literature has reported several e-government evaluation frameworks, several shortcomings still exist in the previous work. The objective of this paper is to propose a formative and holistic framework to remedy the current research gaps. The formative position of the evaluation framework ensures the objectives achievement and the holistic side ensures completeness and continuity of the evaluation process. The framework can be used as a template for researchers and practitioners to assess e-government projects. We demonstrate the applicability and practicability of the framework by applying it to the Korean Government-for-Citizen (G4C) project.


Advancing the performance of Light Water Reactors, Advanced Nuclear Fuel Cycles, and Advanced Reactors, such as the Next Generation Nuclear Power Plants, requires enhancing our fundamental understanding of fuel and materials behavior under irradiation. The capability to accurately model the nuclear fuel systems to develop predictive tools is critical. Not only are fabrication and performance models needed to understand specific aspects of the nuclear fuel, fully coupled fuel simulation codes are required to achieve licensing of specific nuclear fuel designs for operation. The backbone of these codes, models, and simulations is a fundamental understanding and predictive capability for simulating the phase and microstructural behavior of the nuclear fuel system materials and matrices. In this paper we review the current status of the advanced modeling and simulation of nuclear reactor cladding, with emphasis on what is available and what is to be developed in each scale of the project, how we propose to pass information from one scale to the next, and what experimental information is required for benchmarking and advancing the modeling at each scale level.


A hydroponic experiment was carried out to investigate the effects of Cd 2+ on antioxidant enzyme activity and content of MDA of Horsebean.The results showed that when Cd 2+concentration was 0mg/L,5mg/L,10mg/L,20mg/L,30mg/L and 50mg/L,the activity of POD and CAT increased with Cd 2+ increment, while when Cd 2+concentration was over 50mg/L, the activity of POD and CAT decreased.The SOD activity increased with Cd 2+increment up to 80mg/L and MDA content continuously increased with increment of Cd 2+content.


BACKGROUND
It is known that anti-citrullinated protein (a-CCP) antibodies and rheumatoid factor (RF) can be present in systemic sclerosis (SSc) patients, particularly with joint involvement.

OBJECTIVES
The aim of the study was to assess the prevalence of a-CCP antibodies and immunoglobulin M class (IgM) RF, and the relationships between their presence and joint manifestations in patients with SSc.

MATERIAL AND METHODS
The study included 100 European Caucasian SSc patients hospitalized consecutively in the Department of Rheumatology and Connective Tissue Diseases (Lublin, Poland). Anti-citrullinated protein antibodies and IgM RF were determined using a commercial enzyme-linked immunosorbent assay (ELISA) test.

RESULTS
Anti-citrullinated protein antibodies were found in 10 out of 100 (10%) SSc patients and IgM RF in 71 out of 100 (71%) SSc patients. In the study, 90/100 (90%) SSc patients had joint manifestations (arthralgia or arthritis), 34/100 (34%) had arthritis and 6/100 (6%) had a systemic sclerosis-rheumatoid arthritis (SSc-RA) overlap syndrome. Significantly higher a-CCP antibody levels (p = 0.012), erythrocyte sedimentation rate (ESR) (p = 0.029) and C-reactive protein (CRP) levels (p = 0.020) were observed in the SSc group with arthritis. A significant correlation was found between the group with arthritis and the presence of a-CCP antibodies, and between the arthralgia group and the presence of IgM RF.

CONCLUSIONS
The prevalence of RF and a-CCP antibodies is relatively high in SSc, and joint involvement occurs frequently. There was a significantly higher prevalence of IgM RF in the group with joint manifestations. About 1/3 of SSc patients had symptoms of arthritis. Arthritis is connected with the presence of a-CCP antibodies, while arthralgia is connected with the presence of IgM RF.


BACKGROUND
Ulcerative colitis (UC) overall disease severity index (DSI) has been established. A prospective cohort study was performed to find the value of DSI to predict colectomy within one and four years and explored the association between DSI and other indexes.

METHODS
The hospitalized UC patients were enrolled from March 2018 to January 2019 in this single center study. DSI, Truelove&Witts criteria, Mayo index and Seo index were assessed by medical records. Outcome was whether to undergo colectomy within one and four years and was obtained by telephone survey or medical records. Index values of predicting colectomy within one and four years was evaluated using receiver operating characteristics (ROC) curves.

RESULTS
We enrolled 138 of 233 hospitalized UC patients. Within one year, the follow-up period was less than one year for 6 patients and 2 patients had died. A further 9 patients underwent colectomy. The Spearman correlation coefficient between DSI and Truelove&Witts criteria, Mayo index and Seo index were 0.730, 0.839, and 0.843, respectively. Using these indices to predict colectomy within one and four years, the area under the curve of DSI was more than those of other indices and the cutoff value of DSI was 79.

CONCLUSIONS
We demonstrated DSI had a good correlation with other indexes. DSI can be used to predict the need for colectomy within one or four years.


Review(s) of: Gender and scientific discourse in early modern culture, by Long, Kathleen P., ed., Literary and Scientific Cultures of Early Modernity, Farnham, Ashgate, 2010; hardback; pp. 330, 23 b/w illustrations, R.R.P. 65.00 pounds, ISBN 9780754669715.


We study the information leakage to a guessing adversary in index coding with a general message distribution. Under both vanishing-error and zero-error decoding assumptions, we develop lower and upper bounds on the optimal leakage rate, which are based on the broadcast rate of the subproblem induced by the set of messages the adversary tries to guess. When the messages are independent and uniformly distributed, the lower and upper bounds match, establishing an equivalence between the two rates.


Purpose of this study is effective registration of low-amplitude high-frequency components with predictive value - ventricular late potentials (VLPs) - in electrocardiosignals (ECS) by Ist standard lead. 232 signals were preliminary evaluated to detect VLPs by Simson's method. VLPs were detected in 34 signals. Modification of signal-averaged approach was applicated to analyzed signals. Power spectrums of heartbeat signals' terminal part were analyzed in this study. Designed algorithm showed 82.75% of correct decisions. Originality: new parameter to detect VLPs by Ist standard lead lead was proposed. Parameter's threshold value is calculated. Threshold frequencies with maximal percentage of correct decisions were determined. Opportunity to detect VLPs in signals by Ist standard was evaluated: it is possible to detect VLPs using spectral analysis. Practical significance: results will be useful for ECS analysis block in telemedicine systems and onboard communications.


In recently years, the Web service composition becomes a new approach of distributed application integration. The time cost of the composed Web service is one of the most concerned characters by users. Due to the long delay and uncertainty of the Internet, the performance prediction becomes a difficult problem for the Web service composition. A novel performance simulation model, called STPM, is presented in this paper. Based on the stochastic timed Petri net, the STPM model can simulate and predict multiple performance characters, such as the average delay time of the service request, the average length of the service request queue and average response time of the service request etc. To examine the validation of the STMP model for performance simulation of WSC, some simulation experiments have been fulfilled based on the CPN tools, a modeling and simulation tools based on the hierarchical CPN. The experiment results demonstrate the feasibility and efficiency of the STPM model.


Genevieve M. Bieg A STUDY EXAMINING THE EFFECTS OF ATHLETICS ON FEMALES' MATHEMATICAL ACHIEVEMENT 2003/2004 Dr. Louis Molinari Master of Arts in Elementary School Teaching The purpose of this study was to explore the possibility of a correlation between females who actively participated in athletics and a high achievement in mathematics. A comparison of females who actively participated in athletics and females who did not actively participate in athletics was made using an independent samples t-test. The design for this study was the use of a survey, data collection and an independent samples t-test. This study used the sample of forty-one sixth grade females. Each female attended the same middle school and had the same math teacher. Each participant filled out a survey that determined the extent of her athletic participation. Two distinct groups were then made. Each groups' scores on the Terra Nova Assessments and the GPAs were examined and compared using an independent samples t-test. The analysis of the statistics for both instruments proved no significant difference between the two groups of females. The generated null hypothesis for this study was


Utah chub Gila atraria, a temperate freshwater minnow, formed valid otolith annuli (annual growth rings), even when raised in a constant-temperature desert spring environment. This suggests that factors other than seasonal variation in water temperature control annual otolith marking.


This thesis describes theoretical calculations in two subjects: the primordial recombination of the electron-proton plasma about 400,000 years after the Big Bang and electric dipole radiation from spinning dust grains in the present-day interstellar medium. Primordial hydrogen recombination has recently been the subject of a renewed attention because of the impact of its theoretical uncertainties on predicted cosmic microwave background (CMB) anisotropy power spectra. The physics of the primordial recombination problem can be divided into two qualitatively different aspects. On the one hand, a detailed treatment of the non-thermal radiation field in the optically thick Lyman lines is required for an accurate recombination history near the peak of the visibility function. On the other hand, stimulated recombinations and out-of equilibrium effects are important at late times and a multilevel calculation is required to correctly compute the low-redshift end of the ionization history. Another facet of the problem is the requirement of computational efficiency, as a large number of recombination histories must be evaluated in Markov chains when analyzing CMB data. In this thesis, an effective multilevel atom method is presented, that speeds up multilevel atom computations by more than 5 orders of magnitude. The impact of previously ignored radiative transfer effects is quantified, and explicitly shown to be negligible. Finally, the numerical implementation of a fast and highly accurate primordial recombination code partly written by the author is described. The second part of this thesis is devoted to one of the potential galactic foregrounds for CMB experiments: the rotational emission from small dust grains. The rotational state of dust grains is described, first classically, and assuming that grains are rotating about their axis of greatest inertia. This assumption is then lifted, and a quantum-mechanical calculation is presented for disk-like grains with a randomized nutation state. In both cases, the probability distribution for the total grain angular momentum is computed with a Fokker-Planck equation, and the resulting emissivity is evaluated, as a function of environmental parameters. These computations are implemented in a public code written by the author.


As current generations of students are entering the classroom having had years of "screen time," it is imperative to rethink and remake traditional teaching practices. The present paper thus aims to explore multimedia publishing and the possibilities it has to offer foreign language learners in the consumption and production of popular culture texts. As multimodal types of literary texts, podcasting, video publishing and live streaming prove pivotal in enabling students become engaged in global communication.


THE ESSENTIAL PROPERTIES OF BITUMINOUS SLURRIES ARE GRIPPING CAPACITY, LOW WATER PERMEABILITY AND HIGH RESISTANCE TO ABRASION, BOTH WHEN WET AND DRY. IN THIS REPORT, A MEASURING PROCESS FOR DETERMINING WET ABRASION IS DESCRIBED. A SAMPLE OF THE SLURRY IS DRIED OUT, RE-WETTED AND BRUSHED WITH WIRE BRUSHES DRIVEN BY AN ELECTRIC MOTOR. AFTER BRUSHING THE SAMPLE IS WEIGHED, AND THE LOSS IN WEIGHT DUE TO ABRASION IS DETERMINED. /RRL/


It is widely acknowledged that the learning and teaching writing in English is of great difficulty for both learners of English majors and teachers. Although almost all institutions at the tertiary levels offer writing course in English, learners or even teachers consider it a sticky business. Teachers teaching writing are challenged with too much marking work and the learners are anxious about writing compositions. This paper, from the perspective of writing tasks, aims, and methodology, raises and discusses certain issues concerning the status quo in teaching writing in English.


A unified scale for predicting non-specific solvent polarity employs the physicochemical properties of solutes, such as NMR, EPR, electronic transitions, etc., and the equation Δχ=S′P+W in order to produce a scale of non-specific solvating ability. This approach is successful due to the exclusion of data for systems where donor–acceptor interactions exist. In this paper, the Unified Scale is extended to include systems in polar acceptor solvents by using the equation Δχ=EA′EB+CA′CB*+S′P+W, which takes into account both the non-specific and specific donor–acceptor interactions of these solvents with donor solute probes. An experimental procedure which leads to the separation of solute solvation into non-specific and specific components is described.


Digital holographic microscopy (DHM) is an effective method that can be used to investigate transparent objects. The technique allows to get both intensity and phase distributions of wavefronts transmitted through samples without scanning or destructing them. In this paper, a DHM setup with sub-micrometer resolution is used to record the deformation of hydrogels during the swelling and shrinking process. To overcome the out-of-focus imaging caused by the shifting and deformation of the samples, numerical focusing instead of mechanical focusing is employed. The intensity images at different depths can be reconstructed by using one single hologram, and the phase change as a function of the time can be also determined.


The thesis examines to what extent dominant undertakings, within the evolving technology industry, are considered to use an anti-competitive conduct when strategically combining technical tying and different patent combinations. Such conduct may result in leveraging a position from one product market to another, leading to evergreening and possible abuse of such dominant position, in accordance to Article 102 TFEU. The EU patent system, is becoming more centralized, and may contribute to a better-balanced cooperation between competition law and patent law. The US perspective is considered in order to discuss whether potential guidance is needed within the EU legal assessment.


On account of the problems of drawing automatic generation methods and the poor quality of drawings view,Study on intellectualized and rapid adjusting technology of drawing the three-dimensional turning to two-dimensional automatic generation and optimizing Based on parametric template.The system can realize generating drawings automatically and adjust the drawings,view layout,view proportion,and mark location automatically,after model driven,so as to realize the intelligent rapid drawing,ensure the correctness of design,and improve efficiency and quality of design.


The mitochondrial Permeability Transition Pore (PTP) has been characterized in mammals as a Ca2+-activated channel whose opening allows solutes of molecular mass ≤ 1.5 kDa to equilibrate across the inner membrane, potentially causing matrix swelling, rupture of the outer membrane and release of pro-apoptotic factors. Together with Ca2+, the onset of PTP opening is favored by oxidative stress, membrane depolarization and Pi; conversely, acidic pH, adenine nucleotides and Mg2+ are the major physiological desensitizers. So far, cyclosporin A and derived compounds that prevent the binding of the positive effector cyclophilin D, as well as new compounds identified by our laboratory, have been discovered to be potent antagonists of the channel. Whether or not the PTP is a conserved feature in yeast has long been debated. Several studies suggested that yeast mitochondria might present different independent permeability pathways with peculiar features and modulations, including an ATP-activated pathway that might play a role as an energy-dissipating mechanism. A high-conductance channel considered to be the yeast equivalent of the PTP (yPTP) is inhibited rather than activated by Pi and is insensitive to CsA, and due to the lack of a mitochondrial Ca²⁺ uniporter in yeast, its Ca²⁺ dependence has been difficult to assess. In our recent paper (see Publication 1), we confirmed the existence of Ca²⁺-activated PTP in S. cerevisiae, as previously suggested by Shinohara and Coworkers, taking advantage of the Ca2+ ionophore ETH129, which allows the electrophoretic accumulation of added Ca2+. We found that yPTP opening is strongly sensitized by the thiol reagents phenylarsine oxide, copper-o-phenantroline and diamide, which are effective PTP inducers in mammals, and that this effect could be reverted by reducing reagents. Our laboratory recently proposed that F-ATP synthase dimers are the crucial component of mammalian PTP (mPTP). We carried out a Blue-Native PAGE separation of yeast mitochondrial proteins with digitonin, identified F-ATP synthase dimers through an in-gel activity assay for ATP hydrolysis, and reconstituted them in planar lipid bilayer for electrophysiology experiments. Our data show that dimers of yeast F-ATP synthase form a Ca²⁺- and oxidant-activated channel with "flickering" features resembling those of the mammalian PTP, although with a lower conductance of about 250-300 -pS. Like in mammals, activity of the channel was inhibited by ADP and Mg²⁺. These findings provide evidence that the PTP-forming properties of F-ATP synthase have been conserved in evolution. To verify the role of F-ATP synthase dimer in yPTP formation, we analyzed knock-out mutants for subunits reported to be involved in dimerization of the enzyme. These subunits, localized in the lateral stalk, are subunit e (TIM11) and- subunit g (ATP20). ΔTIM11, ΔATP20, as well as double null mutants, did not display the presence of dimers when analyzed with a BN-PAGE. Furthermore, the Ca2+ retention capacity (CRC, a measure of the propensity to pore opening) of mitochondria devoid of subunits e and/or g displayed an increased resistance to yPTP opening. BN-PAGE analysis after treatment with CuCl2, which promotes the formation of disulfide bridges between adjacent Cys residues, demonstrated that some dimers formed upon thiol oxidation even in absence of "dimerization" subunits, which may explain why the yPTP could open at high Ca2+ concentration even in their absence. Very interestingly, these dimers show a channel conductance of about 30 -pS, which is remarkably decreased compared to that measured in wild-type strain. Further analysis in single KO mutant for e- and g subunits is under way in order to define the contribution of single subunits to channel conductance.
To identify the Cys residues affected by CuCl2 treatment (which should be involved in dimer formation following oxidation), we carried out site-directed mutagenesis of each of the Cys residues of F-ATP synthase in the e- and g- null genetic background. There are eight Cys residues in the yeast enzyme (six in subunits encoded by nuclear DNA and two in subunits encoded by mitochondrial DNA). We found that Cys23 of subunit a (ATP6) is the target of oxidation, and mediates formation of a disulfide bridge between the two monomers thereby stabilizing the dimeric form. Another important finding was that the unique Cys of OSCP, the subunit located on top of the lateral stalk of F-ATP synthase, appears to mediate the effect of diamide on PTP activity, at least at low concentrations. Indeed, CRC analysis revealed that OSCP C100S mutant are less sensitive specifically to diamide, whereas the sensitivity to other oxidants is unaffected.
My results provide the first demonstration that yeast F-ATP synthase dimers form high conductance channels analogous to those formed by the mPTP and thus that channel formation is an evolutionarily conserved feature of F-ATP synthases. It is now possible to unravel the many open questions about structure and regulation of the PTP with the powerful methods of yeast genetics.


Taylor and Francis RIAC_A_462138.sgm 10.1080/1 49 71003616292 Inter-Asia Cultural Studies 464-9373 (pri t)/1469-8447 (online) Original Article 2 10 & Francis 1 0 0 00June 010 P u Wi leme p lwil em n@goo lemail.com Inter-Asia Cultural Studies is to be commended for publishing an anniversarymarker in the form of a critical look-back on the work accomplished to date. However, I find myself incapable of responding to this request as generously as I would like. The main reason is one with which I want to conclude this brief note. Suffice it to say at this time that the invitation to contribute a comment from a suitably critical distance risks pushing me – a non-Asian intellectual – into prematurely occupying a position that will become available to me only after a respectable number of Asian scholars have pitched their tents on that site. The main, even though rather trivial comment that I wished to make on the journal's work to date is that there is danger in its success. Since one of the main purposes of the journal was to open up pathways for Asian scholars of cultural studies and what loosely may be called 'cultural activists' of many different kinds to interact, discuss, connect and so on, the first phase of the journal's life and of the back-up organization's activities must be deemed very successful indeed. The danger is then, precisely that IACS risks becoming an Asian companion alongside umpteen cultural studies journals and organisations, all of them practising perfectly respectable variations of cult/studies, none of them making any difference to the overall dynamics that bestow a hierarchy on the fora that constitute cultural studies as an academically bounded field (with job opportunities, career paths, disciplinary demarcations, turf-wars etc.). In other words, once a platform has been developed that is particularly in tune with the requirements of especially young-ish Asian cultural studies scholars, the journal risks becoming just another cultural studies journal or, worse, it risks ticking the cultural studies box in the range of area studies publications. That would be the most pessimistic prospect of all: IACS as a generalist precursor of a series of national cultural studies publications. The second comment that I wanted to submit is derived from Slavoj [ Zcar on] i[ zcar on] ek's recent book First as Tragedy, Then as Farce. He warns against a tendency that besets all cultural studies work nowadays, including many of the contributions to IACS: routinized antiessentialism. [ Zcar on] i[ zcar on] ek writes in a footnote:


An exact parametrisation of the two-state close-curve-crossing reduced scattering matrix for the BNO or DT model is used to define semiclassical deflection functions for impact parameters close to and beyond the crossing radius. These deflection functions connect smoothly with the ones defined from the Stueckelberg scattering matrix for smaller impact parameters and are shown to behave classically as the impact parameter increases through the crossing region.


In general, we can classify the psychological practice in two main blocks. On the one hand, Psychology as its representation in society, like a scientific activity of applicable, useful and profitable knowledge. On the other hand, as a critic and auto-critic perspective, a way of thinking the Psychology that contrast with the first classification, in which actions do not emphasized in capitalize results. The purpose of this reflection is to trace general lines about this Psychology, that we call "weak", a possibility in the middle of a predominant and prevailing "psychological complex", where several practice are legitimize in a mercantilist, health/illness model. This manuscript is an invitation to reflect about the current psychology tasks, in which we present psychology as a liberating intellectual movement, and not as submission movement.


Smart Tbk. is one of multinational integrated palm oil companies which produce palm oil derivative product such as margarine and shortening. The company has problems with the high inventory cost due to un-optimal ingredient inventory system management by PPIC Department. Therefore, need further analysis about inventory planning using Monte Carlo Simulation. The objective of this research is to determine the optimum amount of each ingredient ordering in order to minimize inventory cost using Monte Carlo simulation method and EOQ. Monte Carlo simulation method is used to forecast demand while EOQ method is used to determine the inventory planning by probabilistic inventory model. By using those methods, the company can improve efficiency by Rp 951,542,844 during the year compared to current inventory policy.

  Key words: Inventory, Monte Carlo Simulation, EOQ, Probabilistic


TPS3116Background: Cancer cells contain unique DNA mutations that result in altered amino acid sequences known as neoantigens. Growing evidence supports a central role for neoantigens as targets fo...


A wideband low-voltage millimeter-wave gyrotron traveling-wave amplifier (gyro-TWT) that incorporates precise axial tapering on both the magnetic field and the interaction circuit for broadband operation is discussed. The amplifier operates in the TE/sub 10/ rectangular waveguide mode at the fundamental cyclotron frequency at a beam voltage of 33 kV and a beam current of 1.6 A. By using an electron beam with an alpha of around 0.6, small signal gain in excess of 16 dB is observed over a wide instantaneous frequency range (33%, 27-38 GHz), in good agreement with theory. Work on the large signal characterization of the amplifier is reported. Nonlinear calculations indicate saturated gains of around 16 dB with approximately 30% bandwidth and 10% efficiency.<<ETX>>


Multi-pass wet wire drawing process is used to produce fine wire in the industrial field. The production of fine wire through multi-pass wet wire drawing process with appropriate dies pass schedule would be impossible without understanding the relationship among many process parameters such as material properties, dies reduction, friction conditions, drawing speed etc However, in the industrial field, dies pass schedule of multi-pass wet wire drawing process has been executed by trial and error of experts. This study investigated the relationship among many process parameters quantitatively to obtain the important process information fur the appropriate pass schedule of multi-pass wet wire drawing process. Therefore, it is possible to predict the many important process parameters of multi-pass wet wire drawing process such as dies reduction, machine reduction, drawing force, backtension force, slip rate, slip velocity rate, power etc. The validity of the analyzed drawing force was verified by FE simulation and multi-pass wet wire drawing experiment. Also, pass redesign was performed based on the analyzed results, and the wire breakage between the original pass schedule and the redesigned pass schedule was compared through experiment.


Mobile recommender systems support the decision making process of users by providing suggestions for items that are of potential use for them in a certain mobile context. This dissertation presents a framework that indicates how developers can improve the user experience of mobile recommender systems. A key contribution lies in the evaluation of this framework consisting of concrete presentation guidelines, efficient algorithms, a strategy to automatically generate interactive explanations and a suitable stereotype user model.


Ecology of extreme environments is an area of interdisciplinary research aimed at increasing the efficiency of processes to reduce the concentration of heavy metals from contaminated industrial areas. Authors' research on the influence of heavy metals on the dynamics of planktonic and benthic organisms from the industrially contaminated aquatic ecosystems in Oltenia Plain revealed a numerical abundance of the species of microorganisms, invertebrates and plants linked to the presence and distribution of metal ions. By analyzing the biocenotic structures of the lakes in Cetate – Calafat sector, it was found to have a high degree of trophicity reflected by the quantitative and qualitative composition of communities of planktonic and benthic organisms. With regard to the presence of bivalent heavy metals in sediments and shells of freshwater snails, it resulted that they can accumulate higher level of Mn, Fe, Cu and Zn than the admissible environmental values (0.001-0.01 mg/l) according to Order no. 161/2006. The performed analyzes illustrate the capacity of the pulmonary snails species such as Radix balthica and Lymnaea stagnalis to accumulate metal ions type Mn, Fe, Cu and Zn in direct correlation with the concentration of the respective ions in the soil.


The biosynthetic pathways involved in the formation of four everninomicin antibiotics were studied. Carbon-14 labelled substrates added to liquid cultures of Micromonospora carbonacea var. aurantiaca revealed that acetate, malonate and glucose were good precursors. Degradation of the antibiotics revealed the primary importance of acetate and malonate for the synthesis of the dichloroisoeverninic acid, an aromatic moiety commonto all of the four everninomicins studied, thus indicating its relationship to the biosynthesis of orsellinic acid. The incorporation of the methyl group of methionine into the methoxy group of dichloroisoeverninic acid could also be demonstrated. The remainder of the everninomicin molecule is apparently derived principally from glucose.


Electrically variable transmission family of the present invention the first, second and third differential gear sets, a battery, an electric motor or the two electric machines to function interchangeably as generators, and four or five selectable torque transfer devices (2 provide two clutches and two or a small size and a low cost electrically variable transmission mechanisms including three brakes). Torque-transfer device, and wherein said selectable is used, in combination dog alone or in combinations of two to provide a continuously variable speed range (including reverse) and four mechanically fixed forward speed ratios on EVT. The torque transfer device, wherein the motor brake (s), and the first and second motor / generators are the electrical, including battery reverse mode, EVT reverse mode, reverse and forward launch modes, continuously variable transmission range mode, and fixed ratio mode it is operable to provide five operating modes of the variable transmission.