ABSTRACT In daily typhoon operation, identifying the intensity of typhoons is always a contentious problem, which can be attributed to the absence of direct observational data when typhoons are present on the ocean. When typhoons move to the offshore region, where many automatic weather stations (AWSs) are present, utilizing automatic observations in non-standard conditions is a good way of identifying the intensity or wind of a typhoon. Before identification, AWS data should be conversed or revised based on statistical experiences from a multilayer wind tower. In this study, the intensity of Haikui (1211) at the landing stage (from 08071200 UTC to 08071920 UTC) is revised carefully. Calculating the wind conversion coefficient between different heights from a 300m multilayer tower observation, the wind data caught by two offshore AWSs were converted to the standard wind of 10 meters and used to identify the intensity of the landing Haikui. The maximum surface wind of Haikui in the landing period was about 45 m/s to 48 m/s and then reduced to 40 m/s to 42 m/s approximately just before landing. On the basis of the discussion in this study, the AWS data in a non-standard environment can be utilized to determine the surface wind at 10 m height by arithmetic conversion. This implies that we should pay more attention and patient to the wind data observed in offshore island AWSs during typhoon identification.


Jeremy Beckett's note about Torres Strait Islanders' views on English and the English-based creole spoken by them (AAS 1984:1) raises some interesting points about the history of that creole (see Anna Shnukal, 1984, 'Blaikman Tok: Changing attitudes to Torres Strait Creole', AAS 1983/2:25- 33).


PROGRAMS RELATED TO PIPING FLEXIBILITY: Elastic Center Pipe Stress Analysis The Need for Thrust Blocks in Buried Thermoelastic Resin Pipe First Natural Frequency for Three Distinct Piping Layouts Flexibility Factors, Virtual Lengths and Intensification Factors PROGRAMS RELATED TO PIPE STRESS: Flanged Connection Bolt Tensioning Fillet Weld Sizing Welded Attachment Shell Stresses Allowable Pipeway Spans for Steel Pipe Support Ring Stresses PROGRAMS RELATED TO INTERNAL PRESSURE: Pressure Reinforcing Pads per ASME/ANSI B31.3 Maximum Allowable Working Pressure Minimum Pipewall Thickness Based on Internal Pressure Pipewall Thickness Class Array for Seamless and Plate-Fabricated Pipe SPECIAL APPLICATIONS PROGRAMS: Turbo- Machinery Loading Analysis per NEMA SM-23 and API-617 Buried Concrete Thrust Block Sizing in Cohesionless Soils.


We hypothesized that differential seedling establishment was responsible for the transition from white fir- to red fir-dominated forest. Nearly 2,000 seeds of each species were sown within six fenced gardens that spanned the ecotone (1,902-2,073 m). Germination and seedling mortality were monitored through the first growing season. Red fir germination percentage exceeded that of white fir in all gardens in sites dominated by red fir saplings and overstory trees, and a similar pattern was true for white fir. Survival at the end of the first growing season was low and statistically similar for both species, as was the average length of life for seedlings and the causes of mortality. Relative demographic performances (an integrated measure of germination and survivorship over time) suggest that: 1) open/xeric microhabitats within the ecotone favor white fir over red fir; 2) both open/mesic and shaded/xeric microhabitats favor red fir over white fir; and 3) shaded/mesic microhabitats are equally favorable for both species. Seedlings of red and white fir were grown for 6 mo in a growth chamber that imitated early summer temperature and soil moisture conditions. Red fir seedlings were consistently heavier than white fir seedlings, in part a result of the 2.5 x greater caloric content of red fir seed. Relative growth rates were similar for both. Allocation of photosynthate to roots was greater for red fir than white fir, a result contrary to the expected pattern, given that white fir occurs at more xeric, lower elevations than red fir. No consistent differences between the species occurred in root growth or morphology.


Pregnancy exposure registries systematically evaluate pregnancies and outcomes exposed to a medicinal compound or device during the gestational period. Historically, such programs partner an academic institution with one or more pharmaceutical companies or are run solely by a pharmaceutical company. However, other examples abound. This article describes what a pregnancy exposure registry is, as well as selected methodological challenges they face, using real examples and applications.


In this paper, we propose a vehicular cooperative navigation system using GNSS, vision sensor and radar sensor that are frequently used in mass-produced cars. The proposed cooperative vehicular navigation system is a variant of the Hybrid-Sum Product Algorithm over Wireless Network (H-SPAWN), where we use vision and radar sensors instead of radio ranging(i.e.,UWB). The performance is compared and analyzed with respect to the sensors, especially the position estimation error decreased about fifty percent when using radar compared to vision and radio ranging. In conclusion, the proposed system with these popular sensors can improve position accuracy compared to conventional cooperative navigation system(i.e.,H-SPAWN) and decrease implementation costs.


The stem cells research was the most active area in current cell engineering.The stem cells were classified and defined.The comparative study between embryonic and the adult stem cell was taken,and the applications of stem cells technique were introduced.The great potentiality of the stem cells particularly the embryonid stem cells in medical science and the whole life science were revealed,and the great reforms were made in the medical science area.


In the genome of Arabidopsis thaliana five genes encode members of the FtsH (Filamentation temperature sensitive protein H) protease family with mutations or deletions in their proteolytic site. De ...


The purpose of this research is to know whether the pictures in descriptive text can improve students' reading comprehension or not at the Tenth Grade Students in SMA Negeri 1 Luwuk. The research design in this research was quasi-experimental using non-equivalent control group design. The Independent variable of this research was pictures and the dependent variable was students' reading comprehension. The Population of this research all students of IPA in SMA Negeri 1 Luwuk of the Tenth Grade were about 216 students, each class consisted of 36 students and the sample of this research were X MIPA 1 and X MIPA 2. The instrument used of this research was test. This research has two classes, experimental class and was control class. The data were taken by giving pre-test and post-test both of classes. The data indicated that, there was a significant difference between students' pre-test and post-test in the experimental class. The mean score of students' pre-test of experimental class was (57.02) and the mean score of post-test was (77.97). In experimental class, mean score of post-test was higher than mean score of pre-test. The result of the calculation statistical hypothesis test showed t value was higher than t table (6.618  1.667) where the formula of significance level df = 005. Therefore, it was concluded that there was a significance effect of using pictures to improve student' reading comprehension in teaching descriptive text at the Tenth Grade of SMA Negeri 1 Luwuk . Keywords: Pictures; Students' Reading Comprehension; Descriptive text.


The amount of mass contained in low-mass objects is investigated anew. Instead of using a mass-luminosity relation to convert a luminosity function to a mass function, I predict the mass-luminosity relation from assumed mass functions and the luminosity functions of Jahreiss & Wielen (1997) and Gould et al (1997). Comparison of the resulting mass-luminosity relations with data from binary stars constrains the permissible mass functions. If the mass function is assumed to be a power law, the best fitting slope lies either side of the critical slope, -2, below which the mass in low-mass objects is divergent, depending on the luminosity function adopted. If these power-law mass functions are truncated at 0.001Msun, the contribution to the local density of stars lies between 0.016 and 0.039 Msun pc^-3, in conformity with the density measured dynamically from Hipparcos stars. If the mass function is generalized from a power law to a low-order polynomial in log(M), the mass in stars with M<0.1Msun is either negligible or strongly divergent, depending on the order of the polynomial adopted.


Congenital adrenal hyperplasia (CAH) (OMIM #201910) is a complex disease most often caused by pathogenic variant of the CYP21A2 gene. We have designed an efficient multistep approach to diagnose and classify CAH cases due to CYP21A2 variant and to study the genotype‐phenotype relationship.


Objective To study the modulation of 5-HT(subscript 2A) receptors on rhythmic respiration discharging activity in the transverse medullary slices of neonatal rats. Methods The transverse medullary slices of neonatal rats were made and perfused with homothermal and improved Kreb/s liquid, the respiratory-related rhythmic discharge activity (RRDA) of hypoglossal nerve root was recorded. The slices were divided into two groups. In group I, the slices were perfused with 5-HT(subscript 2A) receptor excitomotory-(2,5-dimethoxy-4-iodophenyl) -2-aminopropane (DOI) dissolved in modified Kreb's solution. In group Ⅱ, the slices were perfused with ketanserine specific antagonist of 5-HT(subscript 2A) receptor. The effects of DOI and ketanserine on RRDA were observed. Results DOI could increase RRDA, prolonged inspiratory time (TI), shortened expiratory time (TE) and respiratory cycle (RC), increased integral amplitude (IA) of RRDA (P<0.01). Ketanserina could inhibit RRDA, shortened TI, prolonged TE and RC, decreased IA (P<0.01). Conclusion 5-HT(subscript 2A), receptor play an important role in the generation and modulation of RRDA in the transverse medullary slice of neonatal rats.


We study in detail the electron energy spectrum produced by the interaction of atomic hydrogen initially in the 2s state with a femtosecond laser pulse. As a first step, we treat the problem within second-order perturbation theory. For that purpose, we analyze in the first instance the off-diagonal continuum-continuum transition matrix elements and derive asymptotic expressions when both the initial- and final-state energies are very close to the ionization threshold. We also consider the diagonal divergence and extend a recent calculation of Madajczyk and Trippenbach [J. Phys. A 22, 2369 (1989)]. By means of a proper analytical regularization of these matrix elements, we show that they may be considered as a distribution, which, in addition to a \ensuremath{\delta} function and its first derivative, involves three principal parts. When this distribution is acting on a given function of energy, it is shown that the calculation of these three principal parts may be carried out fully analytically. We then present results for the electron energy spectrum. Various pulse shapes are considered, and a detailed discussion is given on the contribution of the intermediate continuum states to the second-order probability amplitude.


Objective To study and eveluate the role of anastomat in low colorectal anastomosis.Methods Retrospective study was used to analyze the experience of anastomat technique in pull-through ultralow resection for 22 patients with rectal cancer.Results (1)Complications included anastomotic fistula in 1 patient(4.5%),anastomotic stenosis in 1 patient.(2)The average 5-year follow-up found the local recurrence of 9.1%(2 cases).(3)Perioperative mortality was zero in this group.(4)The defecation freedom and the defecation function became normal three months postoperative.Conclusion The experience suggests the anastomat technique could allow lower colorectal anastomosis in the patients with rectal cancer which would be impossible with traditional hand-sewn method.


Introduction A massive outbreak of botulism in northern Thailand in March 2006 tested international capacity to respond to a public health emergency. Botulism poisoning due to contaminated home-canned bamboo shoots caused illness in 209 villagers, of whom 134 persons were hospitalized and 42 required mechanical ventilation. A global search for Botulinum antitoxin began, involving international agencies, embassies, national laboratories, airlines and commercial organizations in seven countries. Sufficient antitoxin was obtained from four sources for treatment of 90 patients, but with delays in treatment of 5 to 9 days from time of exposure. Rapid local outbreak detection and an effective international response likely prevented mortality and additional morbidity. However, the international response to this public health emergency was informal and conducted through professional relationships rather than through predefined protocol for antitoxin acquisition. Stronger commitment through formal international agreements, including creation of global and regional stockpiles of critical medicines and supplies, is urgently needed. The outbreak On Wednesday, 15 March 2006, several patients sought treatment at Ban Luang district hospital with reports of gastroenteritis starting at 13:00. An outbreak of botulism was suspected, and an investigation was begun when another 10 patients presented to the emergency unit, some with bulbar palsies and respiratory compromise. (1) All patients had eaten home-canned bamboo shoots one day earlier, when approximately 330 villagers attended an annual religious rite in a small village in this district, during which home-canned bamboo shoots from two 20-litre cans were served without heating in small plastic bags for lunch. Over the following week, a total of 209 villagers had the onset of symptoms compatible with botulism. Among the affected villagers, 134 (64%) were hospitalized with paralysis ranging from minor bulbar palsies to quadraparesis; 42 (20%) of patients required mechanical ventilation for respiratory depression. There were no deaths. The epidemiological investigation of this outbreak has been reported previously. (2) The response Authorities in the province declared a public health emergency on Thursday 16 March. Immediately upon establishing a presumptive diagnosis of botulism poisoning, efforts were begun to obtain Botulinum antitoxin, which is life-saving if given within 48 hours. (3) The total number of cases and those with severe neuromuscular impairment requiring ventilatory support increased over the next several days, to 19 patients on ventilators by the third day and 39 by day six. Numbers of patients requiring ventilator support and times of request and deliveries of antitoxin are shown in Fig. 1. The process of obtaining antitoxin was difficult. Telephone and email contacts were established between the Thai public health ministry in Bangkok; embassies in Bangkok, Geneva and London; the World Health Organization in Geneva; the United States Centers for Disease Control and Prevention (CDC) in Atlanta; the National Laboratory in the United Kingdom; and the Japan National Institute of Infectious Disease (NIID) in Tokyo. [FIGURE 1 OMITTED] Ultimately it was possible to obtain 93 vials (treatment courses) of antitoxin from the CDC, the United Kingdom's National Laboratory and NIID in Tokyo. An additional 10 vials were purchased from a commercial source in Canada. The first 20 patients with most severe neurological impairment received antitoxin on day five, and 70 more patients were treated by the ninth day after the exposure. Table 1 shows time intervals from the original exposure, initiation of requests for antitoxin, initiation of procurement from various sources and delivery to the hospital. If Thai authorities had not been able to mobilize 42 ventilators and staff to manage the most severely affected patients, these delays would have certainly resulted in significant mortality. …


Practical teaching system of hotel management major in higher vocational colleges is the key way to realize the training goal.Starting from the occupation ability of hotel industry,combined with the present teaching situation of the practical teaching of hotel management major in higher vocational colleges,the paper discusses the construction of practice teaching system and the concrete implementation method.


In this paper, a class of fractional Sturm–Liouville advection–dispersion equations with instantaneous and noninstantaneous impulsive boundary conditions is considered. At the beginning, the existence of at least one nontrivial ground state solution is proved by the method of Nehari manifold without the Ambrosetti–Rabinowitz condition. Then, the existence of infinitely many nontrivial weak solutions is obtained by using the genus properties. Finally, an example is given to illustrate the main results obtained in this paper.


It is often argued that suspected terrorists captured in the war on terror can be detained just the same way captured enemy soldiers can: until the relevant war is over. But there is a deep disanalogy between suspected terrorists and captured enemy soldiers. Soldiers cannot be held accountable for the use of force (as long as it conforms to the law of war), whereas terrorists normally can. Detaining people who can be held accountable as if they cannot is crossing an important moral line, sacrificing the rights of the individual for the welfare of the whole.


Taking the Xinguang Bridge in Guangzhou as an example,this paper conducts a study of the dynamic behavior and seismic response of long span continuous rigid-frame and steel truss arch bridge under interaction of weak layered soil,weaker layered soil,harder layered soil,rock foundation and group piles.It is found in the study that different foundation soils have considerable influences on the internal forces and displacement of the arch ribs and V-shape rigid frames of the long span continuous rigid-frame and steel truss arch bridge under different seismic time-history excitations.With the increase of rigidity of the foundation soils,the axial forces of the upper chords of the main and side arch ribs and slant legs of the V-shape rigid frames on side of the side spans basically tend to decrease step by step under seismic excitations transverse to,along and normal to the bridge.However,the variations of the in-plane and out-of-plane moment of the V-shape rigid frames do not have obvious regularities with the variations of the rigidity of the foundation soils.


Moniletrix is an autosomal dominant disorder characterized by a structural alteration in the hair shaft with periodic thinning, giving a beaded appearance to the hair. It can be accompanied by follicular hyperkeratosis and koilonychia, along with other findings. We present two cases, a mother and daughter with monilethrix, who also showed an absent lunula in 20 nails. The hair shaft abnormality was clearly distinguished in dermoscopy with the use of a hand piece at office.


An exploratory investigation of the features of means from short-term CPI inflation fluctuation to long-term balance by timeshare adjustment means shows that the lagged CPI items since 1990 tend to have prominent effects on inflation and intensify the inertia of inflation.The market subject tends to hold forward expectations in time of deflation but backward expectations in time of inflation.Financial expenditure helps restrain the rise of price in time of inflation but reverse the fall of CPI in time of deflation.The price of agricultural produce and indexes of stock price tend to clearly have positive effects on CPI inflation and the rise of real estate produces a "transfer effect" to restrain CPI inflation.In time of inflation general loaning,net export and the inertia of inflation are the major promoting factors,but the participation of the price of produce futures and real estate,the indexes of stock price and the equation of ex-factory price of industrial commodity gives a stronger explanatory power to CPI fluctuation.However,the impact of supply has come to be a most prominent factor to inflation just recently.


Substitution reactions of the type Pd(L)X+ + Y− Pd(L)Y+ + X− with L = dien, 1,4,7-Et3dien, 1,1,4-Et3 dien, 1,1,7,7-Et4 dien, 4-Me-1,1,7,7-Et4 dien and 1,1,4,7,7-Et5 dien, X = Cl, Br or I and Y = OH and I have been studied kinetically as a function of [Y−], temperature and pressure. The first-order rate constant k1, for the solvolysis reaction path decreases along the series dien > 1,4,7-Et3dien > 1,1,4-Et3dien ≫ Et4 dien > MeEt4 dien ∼ Et5 dien, accompanied by an increase in ΔH* and almost constant values for ΔS# and ΔV#. The same applies to the second-order rate constant k2 for the direct substitution reaction path in the case of Y = I, and the activation parameters for both k1 and k2 being indicative of an associative reaction mode for all complexes. For Y = OH, a significant [Y−] dependence was observed for the Et4 dien species only, and the value of Δ V# in this particular case favours a conjugate-base mechanism. The results are discussed with reference to related studies reported in literature.


In humans with cochlear implants, functional measures show considerable variation from one stimulation site to another along the electrode array. Our research has demonstrated that (1) the across-site patterns of the functional data are stable over time but differ across subjects; and (2) the across-site patterns are measure specific. These observations are consistent with the hypotheses that implant performance at a given stimulation site is dependent on specific conditions near the site, and that the various functional measures do not all depend on the same conditions. However, we lack direct evidence as to the specific conditions leading to the site-specific differences in performance in humans. Studies in our guinea pig laboratory and elsewhere have demonstrated highly significant correlations between psychophysical or electrophysiological measures of implant function and anatomical measures of cochlear health. Furthermore, the correlated anatomical features differ across functional measures. Finally,...


The effect of calcium into coal fly ash on trace elements leaching concentration has been investigated through the addition of suppressing material. This study aims to provide the useful reference in controlling As leaching concentration into the environment. Suppressing material, as the by-product of other industries which contain high calcium, has been proven in decreasing of arsenic (As) leaching concentration from coal fly ash. There are three suppression materials that have been tested, that is: calcium hydroxide (Ca(OH)2), paper sludge ash (PS3) and filter cake (FC). Ca(OH)2 and PS3 show almost 85-90% decreasing in As leaching concentration based on ICP analysis. Moreover, the XPS analysis results show that calcium oxide (CaO) is consisting in PS3 and calcium carbonate is consisting in fly ash sample H.


In this work,we demonstrate the technology of wafer-scale transistor-level heterogeneous integration of Ga As pseudomorphic high electron mobility transistors(p HEMTs) and Si complementary metal–oxide semiconductor(CMOS) on the same Silicon substrate.Ga As p HEMTs are vertical stacked at the top of the Si CMOS wafer using a wafer bonding technique,and the best alignment accuracy of 5 μm is obtained.As a circuit example,a wide band Ga As digital controlled switch is fabricated,which features the technologies of a digital control circuit in Si CMOS and a switch circuit in Ga As p HEMT,15% smaller than the area of normal Ga As and Si CMOS circuits.


Anaesthetic efficacy of eugenol was investigated on Pterophyllum scalare. A total of 130 fish with average weights of 1.0 ± 0.5, 5.0 ± 1.0 and 10.0 ± 1.0 g were subjected to 1.25, 2.5, 4.0, 5.5 and 7.0 mg/L eugenol, and behavioural responses were observed. Induction and recovery times were significantly affected by the interactive effect of eugenol concentration and fish weight (p < .05). Generally, 49.9–128 s after exposure to 1.25–7 mg/L eugenol, fish reached stage 3. Fish entered stage 4 over 55–135 s post exposure to such concentrations. Recovery time was 393.5–597.7 s in all sizes. Any increase in eugenol concentration led to a significant decrease in the induction time with a subsequent increment of the recovery time. Concentrations of eugenol and fish size along with their interactive effects have significantly contributed to the regression models, with concentration recording the highest beta values for stages 1, 2, 3 and 4 (−0.903, −0.898, −0.976 and −0.864 respectively) and the product of size and anaesthetic concentration for full recovery in smaller fish (0.647) and eugenol concentration in larger ones (0.967). Recovery time was fitted to induction time to stage 4 via quadratic and linear regression models in smaller and larger fish respectively. Results revealed the minimal eugenol concentration to induce anaesthesia in various size classes of angelfish in less than 3 min was 1.25 mg/L. Our results showed eugenol as an effective and safe anaesthetic; however, it is not advisable for live fish transportation.


In this paper is presented the design, construction and evaluation of an autonomous mobile robot, designed to outdoor competitions. The category of outdoor competition, in Brazil named Trekking Pro, is based on a mobile robot in an open field, which must pass through preset coordinates. A commercial (at first remote controlled) robot was adapted for autonomous operation. The perception of the robot consists of 9-axis Absolute Orientation Sensor and an encoder. At fist, the system was simulated in a ROS (Robotic Operation System) environment integrated with a scene V-REP (Virtual Robot Experimentation Platform). PID controllers, were used in implementation. Afterwards, a prototype was built, that participated in a competition with success, winning the first place. Both simulation and real-world experimental results of the constructed prototype are shown in detail. The robot described in this paper was the champion of the Winter Challenge 2018 (Robocore - Brazil) in the Trekking Pro category.


Facing the demands of medical and health services and the opportunities and challenges of big data, traditional medical informationization cannot effectively cope with them. This paper designs a three-tier model of medical cloud for medical data processing, which integrates "cloud architecture" with the existing hospital information system perfectly by using private cloud of hospital, and establishes a new medical resource projection mode of "cloud service" hospital information system as service by using medical community cloud. And the medical data processing system can effectively use "cloud computing" to process and utilize medical data. With cloud computing as the brain, big data as the soul, hospital informatization as the carrier, based on cloud computing and big data core technology and concept, the application of medical cloud and big data is realized in stages under this model.


Gypsum maze caves of Western Ukraine are characterized by a complex spatial structure, which can be treated as fractals and can be studied using appropriate mathematical tools. Capacitance and correlation fractal dimensions of largest gypsum caves of the region were calculated. The results were used to predict findings of new, yet undiscovered parts of cave mazes.


An algorithm is presented to automatically delineate the endocardium in echocardiograms. The algorithm uses an optimization technique to overcome the poor image quality of existing algorithms and to use dynamic information. The information used in the process consists of grey level gradient, texture gradient, smoothness of the contour, and deviation of the present contour with respect to one of the previous video frames. The optimization algorithm locates the best compromise between image information and continuity in space and time. The automatic delineation is used for wall motion analysis and calculation of volumes and volume changes of the left ventricle (LV). An assessment of the accuracy of the volume calculations and indirectly the delineation was made by comparing the actual and calculated volume of the LV of excised dog hearts filled with a known amount of water. It is demonstrated that the dynamic programming technique is promising in detecting the myocardial borders.<<ETX>>


Melt dispersion technique was investigated for carnauba wax microparticles production. Microbeads with spherical shape and narrow size distribution were produced. The main objective of this study was to investigate the effect of significant process variables (initial wax concentration, stirring speed, stirring time, and surfactants) on sphericity, size distribution, and morphological properties of wax microparticles. Optimal conditions were evaluated on the basis of particle size distribution and visual analysis. Surface morphology of microparticles was characterized by scanning electron microscopy (SEM). Effects of process conditions on the size distribution of particles were evaluated by sieve analysis. Main purpose of these investigations was to apply optimized parameters to aroma encapsulation for their use in food and feed industry.


A rare case of spindle cell hemangioendothelioma (SCH) was reported. The patient was a 62-year-old female, whose chief complaint was a soft nodule on the left submandibular region. She was treated by surgical excision. Pathological diagnosis was SCH. There has been no sign of recurrence to date. This is the first case of SCH at the submandibular region.


Dynamic web content is a challenge to archive, because the underlying web technologies are constantly advancing. For example, new JavaScript frameworks and Scalable Vector Graphics web elements make the capabilities of archiving tools a moving target. Moreover, the order of execution of events on a web page can affect the page state and the crawling path. To date, a smart crawler capable of solving the daunting task of driving all action elements on a page with all possible traversal paths does not exist, due to the complexity and cost of operation. Consequently, conventional crawling usually does not activate interactive elements on the page, and thus preserves pages with missing information. In our approach, we use a pre-crawl curated web navigation session to record the navigation plan (or Trace) via our Chrome browser extension. We implemented a Trace-driven crawler that can take the navigation plan recorded in the Trace and apply it to a class of webpages with like HTML layouts and interactive options. The Trace-driven crawls are particularly useful for sites where software development work and scholarly research are now kept, such as GitHub, Slideshare, and Publons. Our crawler and other tools are open-sourced to help the web archiving community efficiently capture the valuable information now housed in the interactive web of productivity portals.


Mutations in genes encoding for cilia associated proteins lead to complex developmental defects and although individual ciliopathy diseases are very rare, together they represent a significant disease burden. Due to extensive genetic heterogeneity and phenotypic as well as genetic overlap, molecular diagnosis using Sanger sequencing has been proven very difficult in the past. However, the development of Next Generation Sequencing techniques such as Whole Exome Sequencing (WES) offers new diagnostic tools. We have investigated 61 Jeune Asphyxiating Thoracic Dysplasia (JATD), 37 Bardet-Biedl-Syndrome (BBS), 7 Joubert and 9 other ciliopathy cases (total of 114 cases) using WES and were able to identify the disease causing gene in approximately two thirds of all cases with 50% of JATD and Joubert cases but up to 90% of BBS cases caused by mutations in known disease causing genes. Mutation analysis led to revision of the initial clinical diagnosis 10% of the cases and revealed new phenotype-genotype associations, especially in JATD. However, the proportion of solved cases was a lot lower among less well defined (potential) ciliary phenotypes. In contrast to BBS cases, where we frequently identified two loss of function alleles per proband, all JATD cases carried at least one missense allele confirming the hypothesis that JATD patients are hypomorphic for the disease while BBS patients often represents true "Nulls". More than 2 mutated alleles were identified in 25% of the BBS patients, however, the third allele was always a missense allele with exception of a single case. Copy number variations in known as well as in new genes were identified in approximatively 10% of solved cases from the WES data. We have further identified several new genes (some previously associated with Intraflagellar transport (IFT) as well as "new candidates") for which functional studies using zebrafish and cell culture model systems are currently under investigation. Summary: Our findings in this large non-motile ciliopathy cohort demonstrate that WES is a very efficient tool in the genetic diagnosis of heterogenous recessive disorders and that deep phenotyping facilitates the genetic diagnosis. A surprisingly large number of cases is caused by mutations in known genes and this study also identified several new ciliopathy genes. Compared to NGS gene panel sequencing, WES potentially offers additional opportunities to identify new genes previously not associated with the condition investigated.


Recently the rapid growth of on-line game industry is in the limelight as next generation industry with whole industry influencable. But the dark side of quantitative growth of game industry has a problem that service quality control for customers doesn't get realized. So this industry doesn't build up the foundation of the sustainable growth. In this situation, on-line game industry can grow by revisiting and using game continuously through continuous customer satisfaction. The existing study were game of developmental view or general web-site estimation model. But this research studies and conducts an more effective setting plan of estimation model by showing estimation model of on-line game under the reality of on-line game industry. Especially this study tries developing comprehensive model of people in all age with considering casual on-line game that uses the bulk of age in on-line game fields. In other words, this research tries offering game company chances that can give special services in on-line game industry by showing estimation model for web-site that classifies into casual one of on-line games and studying factor of web-site quality on users' characteristic.


The article deals with the topic of contemporary criticism of Orthodox Christianity in Russia. A detailed picture of the phenomenon of religious criticism in today's socio-cultural discourse is presented, several leading directions criticism of orthodoxy, both from representatives of the church, and from among the representatives of secular society is analyzed. Criticism of Contemporary Orthodoxy reflects the contradictory situation of religion in the modern world. The collapse of the Soviet ideological system created a certain ideological vacuum which was to fill the Russian Orthodoxy. Selected influenced by internal "Right Forces" conservative development path gradually became more controversial and contrasted with liberalism 90s in Russia. Sharp government policy in the direction of conservatism during the presidency of Vladimir Putin considerably influenced the process of convergence of church and state. In the official Church rhetoric were conflicting narratives, in terms of many in the liberal society like "Russian world" and "Symphony of spiritual and secular power". In general conservative course of Russia socio-political role of the Church began to gradually narrow to the State Institute of spreading the conservative and nationalistic ideology. This contradictory position of the Church caused a consistent criticism on the part of members of secular society, and by the different origin and political orientation of internal Church groups. Secular society representatives focused on the growing level of ecclesiastical fundamentalism, political and economic activity of the Сhurch, its rapprochement with the state and attempting to influence the institution of public education. Liberal-minded members of the Сhurch community criticized domestic conservatism, lack of reforms, strict hierarchy, low educational work of the Сhurch. Conservative circles of ROC criticized the passivity of the Russian Orthodox Church in opposition to ecumenism and globalization processes.


Ayurveda is the age-old science of healing which encompasses the scriptures of Acharyas like Charaka, Sushruta, and Vagbhata etc. What differentiates Ayurveda from other Pathy is its supreme objective that is to help maintain the health of healthy individual and cure of diseases of a patient. Shotha (edema) is dealt in Ayurveda by different names such as Shotha, Shopha, Shvayathu, Utsheda, samhata etc. In Charaka Samhita, Chikitsa sthana chapter- 12 Shvayathu chikitsa, Acharya Agnivesh questioned the great sage- Lord Atreya about the etiology, sign and symptoms and treatment of Shvayathu roga regarding which the Lord Atreya explained in detail about the disease. Although, Shotha has been documented in Charaka Samhita, Sushruta Samhita, Ashtanga sangraha but the profound essence of pathogenesis is found in Madhava nidana (700 AD) which is influenced by the Brihat trayees. In clinical practice, many patients come with the symptom of hasta-pada Shotha (swelling of the limbs) and without the proper knowledge of Ayurvedic literature, it is very much difficult for an Ayurvedic practitioner to differentiate them as whether it is a symptom of disease or prodromal symptom or complication of a disease etc. This paper is an honest effort on differentiating hasta-pada Shotha in different diseases or conditions.


Although 'research income' is one of the most common indicators for assessing research quality, its validity has never been systematically investigated. The conditions under which Australian and German physicists obtain external funding were analysed in a comparative qualitative study. The study demonstrates that success in obtaining external funding is only partly related to the quality of researchers and their proposals. Therefore, the validity of a straightforward counting of external funding must be assumed to be low. A comparison of external funding with citation indicators shows ways to improve the validity of indicators based on external funding. Copyright , Beech Tree Publishing.


Objective. Intrathecal baclofen (ITB) has become the first choice in the management of deleterious spasticity that does not respond to oral and intramuscular medications following spinal cord injury, traumatic brain injury, and cerebral palsy. The usefulness of ITB in severe spastic hemiparesis following stroke is studied. Methods. A total of 8 patients underwent clinical and video assessment following ITB bolus application (n = 5) and during continuous infusion via a temporary catheter system (n = 3). Results. The mean daily dosage alleviating spasticity on the hemiparetic side—without affecting the nonparetic side—was 119 μg/day (range 50 to 360 μg/day). However, 6 patients experienced functional deterioration as ITB weakened their paretic side such that the antigravity pattern they used for ambulation was suppressed. In 2 patients, spasticity-associated pain and spasms subsided and they underwent implantation of a long-term drug delivery system. Conclusions. ITB may reduce spasticity in a dose-dependent manner irrespective of its origin. Although not primarily antinociceptive in humans, ITB may alleviate pain if arising from increased muscle tone. A functional benefit may result if ITB can uncover "subclinical" motor control that had been suppressed by spasticity. However, when a patient uses antigravity patterns for ambulation in the absence of more complex motor control, ITB may cause the loss of residual walking ability, which becomes a major limitation for patients with hemiplegic stroke.


We present a general formalism describing the propagation of an arbitrary multi-particle wave packet in a one-dimensional multimode chiral channel coupled to an ensemble of emitters which are distributed at arbitrary positions. The formalism is based on a direct and exact resummation of a diagrammatic series for the multi-particle scattering matrix. It is complementary to the Bethe Ansatz approach and to approaches based on equations of motion, and it reveals a simple and transparent structure of scattering states. In particular, we demonstrate how this formalism works on various examples, including the scattering of one- and two-photon states off two- and three-level emitters, off an array of emitters, as well as the scattering of coherent light. We argue that this formalism can be used constructively for the study of the scattering of an arbitrary initial photonic state off emitters with an arbitrary degree of complexity.


Cultivating and improving the property management talents' quality is a realistic subject which must be discussed and studied under the new situation in enterprises.It is suitable for market economy.This paper expounded some humble opinions on the cultivation of property management talents' quality from the present situation of property management talents' quality in our country and the requirement of the society,for reference to everybody.5refs.


This paper presents a fatigue testing method using a multi-notched test specimen for the purpose of estimating the distribution function of fatigue crack initiation life by a small number of fatigue tests. Emphasis is put on the effective use of the fatigue data provided by one test specimen and to decrease the number of specimens required in the fatigue tests. The experimental results indicate that two or three multi-notched specimens are enough to determine the distribution function of crack initiation life of practical level.


The model for end-stage liver disease (MELD) is a good predictor of 3-month mortality for waitlisted patients with end-stage liver disease (ESLD). Conversely, the impact of MELD in predicting post-transplant survival has been a matter of debate since its introduction as the allocation system. The paper by Gy€ ori et al. (1) published in this issue of Liver International addresses the effects of delta-MELD, defined as the MELD-point increase from listing to liver transplantation (LT), on post-transplant survival within the Eurotransplant region. This study shows that a delta-MELD ≥ 10 (10point increase in MELD score from listing to transplantation) carries a 10% increase in 1and 5-year mortality after LT. These results point towards the different likelihood of survival after LT between two different ESLD patients with the same MELD score at transplant depending on how rapidly liver and renal function worsens as assessed by MELD in the 4 months before LT (Fig. 1). These results are in agreement with those reported from a single UK centre showing a 14.1% increase in 1-year post-transplant mortality of recipients with a delta-MELD > 1 (2). It is worth noting that both results must be read in the context of very short waiting times (median time less than 4 months from listing to transplantation). By contrast, the median time on the waiting list in the US was 11 months in 2013 for patients with MELD 15–34 (3). Would these results be reproducible in the UNOS setting or other countries with longer waiting times? The conclusions are consistent with previous studies suggesting that sicker patients, especially those with ongoing deterioration of liver function, have a significantly higher mortality after LT (4, 5). However, other well-designed studies have been unable to detect different outcomes or to set reliable MELD cut-off values to determine a poor outcome (6–8). The current definition of delta-MELD as a MELD increase from listing to transplantation classifies patients with a rise of 15 points of MELD (from 15 to 30; delta-MELD = 15) over a 1-year period identically to other patients with the same delta-MELD of 15 in barely 4 months. A new delta-MELD definition as the increase in MELD in a predetermined time-frame before LT or the slope of MELD increase on the waiting list would eliminate the bias resulting from different waiting times among different transplant regions, and might be more sensitive in detecting patients with poorer outcomes in the same MELD range. Therefore, delta-MELD should be adjusted by time in order to be comparable in different series of patients. Post-transplant mortality increases linearly among MELD ranges from 10 to 25–30 and increases exponentially at MELD scores higher than 25–30 (4, 6, 9). This observation entails a non-linear relationship between MELD and post-transplant mortality with incremental hazard ratios for mortality per point of MELD beyond a MELD of 25. Therefore, when using delta-MELD it is unclear whether patients with a MELD increase from 15 to 25 will have a similar posttransplant survival compared to those with a MELD increase from 25 to 35. The non-linear increase in post-transplant risk by MELD at transplant should be considered in order to set a reliable delta-MELD cutoff level. In the study by Gy€ ori et al., the survival of patients with a delta-MELD ≥10 was lower compared to those with a stable MELD score of 30, suggesting the marked effect of the dynamic behaviour of liver disease and renal dysfunction before LT on post-transplant mortality. It seems evident that a rapid deterioration of hepatorenal function carries greater risk than being stable in the previous months. However, it is also evident that a prolonged situation of severe hepatorenal insufficiency, even if stable, is associated with increased post-transplant mortality. Further analyses assessing the interaction between delta-MELD and MELD at transplant with post-transplant mortality are needed to figure out this matter. Appropriate selection of patients and variables are essential to improve the prognostic estimation of posttransplant survival. Hepatocellular carcinoma, hepatitis C virus infection (2, 10) and the functional status of the receptor are important factors in shortand longterm post-transplant mortality (11). Simple variables such as life support, ventilatory support or renal replacement therapy influence the likelihood of survival after LT (6, 12, 13). Renal failure and scores such as SOFA or APACHE before LT also predict posttransplant survival (14, 15). Some studies have addressed the additional effect of donor and surgical variables on the outcome of liver transplant recipients


The living condition and psychological characteristics of vocational college students has aroused wide social attention. It is especially important at present to study vocational college students' frustration psy-chological characteristics and rules, to discuss the importance of frustration on the growth of college students on the basis of analyzing students' behavior of frustration reaction and the cause, and to seek the basic appro-aches of carrying out frustration education among college students.


A laser synthesis scheme via the superposition of single-color and hyper-Gaussian pulses is proposed, and the synthesized laser pulse is adopted to interact with pre-aligned molecules for the production of an isolated attosecond pulse (IAP). The numerical results based on strong-field approximation disclose that the proposed scheme is efficient for the generation of an IAP under suitable hyper-Gaussian parameters, and the intensity of an IAP is sensitive to molecular pre-alignment angles, and thus an optimal set of hyper-Gaussian parameters and pre-alignment angles can support the strongest IAP.


In recent years due to the magnificent development in CMOS technology to reduce area and power of chip designs take attention in research area. Decoder plays an important role in the code conversion and encryption of codes. It is having application in much area. A decoder is used to change a code into a set of signals and translate the encoded data in its original form. In this paper Decoder has been designed and simulated using different CMOS layouts. Design methodologies are used such as standard cell based design, semi custom design and full custom design of the Decoder to reduce area, power and size of the circuit. The paper analyzes and optimizes area and power of the Decoder using 90 nm technologies. The area gets reduced in full custom design by 50.57% from standard layout and 42.68% from semi custom design. The complexity and area get reduced in the full custom designed.


Background and Hypothesis Quantitative acoustic and textual measures derived from speech ("speech features") may provide valuable biomarkers for psychiatric disorders, particularly schizophrenia spectrum disorders (SSD). We sought to identify cross-diagnostic latent factors for speech disturbance with relevance for SSD and computational modeling. Study Design Clinical ratings for speech disturbance were generated across 14 items for a cross-diagnostic sample (N=343), including SSD (n=97). Speech features were quantified using an automated pipeline for brief recorded samples of free-speech. Factor models for the clinical ratings were generated using exploratory factor analysis, then tested with confirmatory factor analysis in the cross-diagnostic and SSD groups. Relationships among factor scores, speech features and other clinical characteristics were examined using network analysis. Study Results We found a 3-factor model with good fit in the cross-diagnostic group and acceptable fit for the SSD subsample. The model identifies an impaired expressivity factor and two interrelated disorganized factors for inefficient and incoherent speech. Incoherent speech was specific to psychosis groups, while inefficient speech and impaired expressivity showed intermediate effects in people with nonpsychotic disorders. Network analysis showed that the factors had distinct relationships with speech features, and that the patterns were different in the cross-diagnostic versus SSD groups. Conclusions We report a cross-diagnostic 3-factor model for speech disturbance which is supported by good statistical measures, intuitive, applicable to SSD, and relatable to linguistic theories. It provides a valuable framework for understanding speech disturbance and appropriate targets for modeling with quantitative speech features.


The aim of this paper is to provide a suitable method to estimate the volatility parameter for the purpose of real option project valuation, especially that of renewable and traditional energy projects. The method is based on the concept of implied volatility of financial options. Then, we obtain implied volatilities for renewable and traditional energy firms by using their debt-to-equity ratios instead of "moneyness" or the strike price used in the case of financial options. For a given debt-to-equity relation of the project, the implied volatility is obtained by employing the stochastic alpha-beta-rho (SABR) model. Our methodology may be extended to find the volatility of any real option


RESUMO: O grande desenvolvimento das atividades da construção civil gera uma preocupação dos profissionais de maneira geral em relação à quantidade de resíduos produzidos nas obras. A remoção desses resíduos descartados irregularmente tem um alto custo para os municípios. Partindo deste princípio, o presente trabalho tem como objetivo avaliar a viabilidade da adição de resíduos de construção em solo para melhoramento de suas propriedades mecânicas para aplicação em camadas de pavimento. Nesta pesquisa foram utilizados 2 tipos de resíduos: resíduos de bloco de concreto, denominados aqui por resíduo de ABSTRACT: The development of civil construction activities generates a concern of the professionals in general regarding the amount of waste produced in the construction works. The removal of these irregularly discarded residues has a high cost for the cities. Based on this principle, the present work aims to evaluate the feasibility of adding construction waste to the soil to improve its mechanical properties for application in pavement layers. In this research, two types of waste were used: concrete block waste, referred to here as white construction waste (RCB), and ceramic block construction waste, referred to here as red construction waste (RCV). The soil used in the research consists of a residual soil typical of the city of Rio Verde-GO, Brazil. This soil was collected and sent to the Geotechnics laboratory of the University of Rio Verde, where characterization, compaction and California Bearing Ratio (CBR) tests were carried out. Construction waste (RC) was added to the separate samples for compaction, by means of mass substitution, so that tests were carried out without addition (reference soil), with mass substitution of 10, 20, 30 and 40% of the RCB (available in greater quantities for research) and mass substituition of 10 and 30% of the RCV. The compactions were carried out with a large cylinder and Intermediate Proctor energy, according to NBR 7182: 2016, corrected version 2020. The results showed that the increase in the RC content added in the samples results in the reduction of the optimum compaction moisture, as well as in the increase maximum dry apparent density, CBR and soil expansion, although the expansion increases were not significant. It can be concluded that the addition of RC in paving soils was beneficial for the studied soil, since when compared with the reference values in the DNIT manual (DNIT, 2006), the increase in CBR allowed that the soil being applied in the sub-base layer of a road pavement in three different dosages. However, it's necessary to be aware with the expansion values obtained, since for soils with relatively high expandability, the addition of RC can further worsen this situation.


In the pre-national era in the Balkans, ethnonyms could have different meanings and refer not only to ethnic, but also confessional, social and occupational groups. In addition, a person's claims about his/her ethnic or national appurtenance had a different importance, other emotional connotations and moral implications depending on the historical period, social status and educational level of the speaker. In our presentation we aim to show differences in understanding of ethnic appurtenance in the village and the city, relying on available information on the status in the Bulgarian city of Plovdiv and the surrounding villages. It appears that political maturing of ethnic consciousness in the village took place partially as resistance to the cultural influence of French Enlightenment, which was promoted and spread in cities.


Background— Smoking is a major risk factor for cardiovascular events. One of the potential mechanisms may be related to both coronary endothelial dysfunction and increased inflammatory response. The present study was designed to test the hypothesis that smoking is associated with epicardial coronary endothelial dysfunction and inflammation. Methods and Results— Coronary endothelial function in response to acetylcholine was assessed in 881 patients (115 current smokers and 766 nonsmokers, including 314 previous smokers). Smokers were significantly younger than nonsmokers (43±1 versus 51±1 years, P<0.0001), had more epicardial vasoconstriction in response to intracoronary acetylcholine (−19±2% versus −14±1% change in coronary artery diameter, P=0.03), and were more likely than nonsmokers to have epicardial endothelial dysfunction (46% versus 35%, P=0.005), but their microvascular endothelial function was intact. Smokers had higher white blood cell counts than nonsmokers (7.7±0.2 versus 6.6±0.1×109/L, P<0.0001), higher myeloperoxidase (156±19 versus 89±8 ng/mL), higher lipoprotein-associated phospholipase A2 (242±12 versus 215±5 ng/mL), and higher levels of intracellular adhesion molecule (283±14 versus 252±5 ng/mL). There were no differences in the levels of C-reactive protein, fibrinogen, or vascular cell adhesion molecule between the groups. Conclusion— Young smokers are characterized by epicardial coronary endothelial dysfunction, preserved microvascular endothelial function, and increased levels of inflammatory biomarkers and oxidative stress. The present study provides further information regarding the potential mechanisms by which smoking contributes to cardiovascular events.


Abstract Growing demand for local food has spurred the emergence of aggregation and distribution businesses, called food hubs. They developed to retain the values of the local food movement, help small farmers achieve economies of scale, and supply large markets. While appearing as an innovative solution to several key constraints of local food systems, there is debate on how these businesses should function and whether the insertion of a middleman breaks down the basic premise of local food, namely the focus on face-to-face transaction. This paper highlights the affective nature of local food purchases, examining ethnographically how one particular food hub with close ties to the local food movement in Atlanta, Georgia contends with this issue as it articulates with larger markets. It finds that building a resilient and sustainable local food system beyond the level of direct markets necessitates illuminating the role affect plays in economic decision-making.


BA.2 is a novel omicron offshoot of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has gone viral. There is limited knowledge regarding this variant of concern. Current evidence suggests that this variant is more contagious but less severe than previous SARS-CoV-2 variants. However, there is concern regarding the virus mutations that could influence pathogenicity, transmissibility


Aim: to present a clinical case of pancreatic PEComa with liver metastases with an emphasis on morphological features, radiology diagnostic methods and features of treatment tactics, allowing practitioners to get an idea about this rare mesenchymal tumors composed of "perivascular epithelioid cells", and a review of literature data on pancreatic PEComa, including 32 author's cases.General statements. A 22-year-old woman who was surgically treated for pancreatic head PEComa with infiltration of the duct of Wirsung, common bile duct, duodenal wall, focal invasion into the blood and lymphatic vessels, and perineural space infiltration. Synchronously, metastases were detected in both liver lobes, for which she took Everolimus for 6 years under the control of radiology methods with dose adjustment and frequency of administration. At the A.V. Vishnevsky National Medical Research Center of Surgery, the patient underwent right-sided hemihepatectomy and atypical resection of II-III liver segments.Conclusion. To determine clearer criteria for the diagnosis and differential diagnosis of PEComa, to identify criteria for the malignancy of these tumors, to develop treatment tactics and further dynamic monitoring, a set of statistical data of significant group and randomized clinical trials are needed. Pancreatic PEComas in this group are extremely rare and often have a benign course. The presented clinical case demonstrates the most malignant form of this tumor with localization in the pancreas and liver metastases.


Pre-construction surveys for spring landbird migratory stopovers were conducted at the Port Ryerse Wind Farm in Feature LBMS01. Feature LBMS01 is greater than 5 hectares, located within 5 km of Lake Erie, and contains a variety of habitats including forest, plantation, and agriculture. These attributes contribute to the potential for this habitat to be used by migratory landbirds as a resting and foraging stopover area (MNR 2012). Surveys conducted throughout this feature in fall 2012 found this feature to be significant Landbird Migratory Stopover habitat based on migratory bird observations, the details of which are included in the Natural Heritage Assessment for the Port Ryerse Wind Farm (Stantec, 2013). This feature was surveyed over 20 early-morning visits in the fall of 2012. Ten of the 20 visits had greater than 200 individual birds and all 20 visits had greater than 10 species. Greater than 35 species were observed over the entire season.


The societal cost of heart failure (HF) is matched by few other medical conditions. More than 670 000 new cases will be diagnosed this year.1 It commonly affects the aged and is associated with other chronic illnesses. Despite significant improvements in outcomes associated with contemporary medical and electric therapies, HF tends to be a progressive condition with a median survival of only 2 to 3 years after diagnosis.2 In addition, HF is the second most costly condition for Medicare.3 The total expenditure on this disease in the United States is estimated between $20 to $39 billion,1,4,5 which corresponds to 1.5% to 4% of total health care costs.6 Further, the majority of medical financial resources are consumed in the final 2 years of life, a cost estimated at nearly $155 000.7

Patients with advanced HF failing optimal treatments have limited therapeutic options. A small subset may qualify for cardiac transplantation, but stringent candidacy criteria and a limited supply of donor hearts limits its value to the larger HF population. In the past 5 years, improvements in left ventricular assist devices (LVAD) have made this a viable option to bridge a patient to transplant (BTT) or as permanent therapy (Destination Therapy, DT). The inability to define the size of the population that may ultimately be candidates for VAD therapy, particularly as DT, has led to widespread angst about the health care cost implications of this technology. The primary focus of this article is to critically review the available literature on the cost of VADs as well as alternative treatments for advanced HF.

Patients with advanced HF have a 1-year survival of only 10% to 25%.8 Initial clinical trials of older pulsatile flow LVADs used as destination therapy demonstrated 1-year survival of …


In today's development of SMEs are dominated from culinary, travel and fashion, so it needs reinforcement and development of the right business model in order to continue to survive. Java Seven is a fashion group SME that has a main product in the form of shoes and bags that require reinforcement and development of the right business model so as not to lose with its competitors. This study aims to perform Analysis of Business Model Strengthening Using Business Model Canvas. In this research will be strengthening business model that occurs in Java Seven by using business model analysis canvas. After getting the data fo'[rm the business model of Java Seven will then be used additional analysis of SWOT to strengthen the business model of SMEs Java Seven itself. After that will form the results of strengthening and development of business models Java Seven. Data collection method is done by interviewing two informants from Java Seven. And also analysis through kuisoner which is useful as complement of data to two informant. Based on the results of data processing can be seen that the form of business models through business model analysis canvas Java Seven owned is good enough because the business model currently owned able to meet the Nine element building blocks on Business Model Canvas. But some blocks such as value proposition, revenue streams, cost structure, customer segments and channels have a high threat and threaten the business model of Java Seven so it needs to be strengthened and development. And in the end Java Seven will have a new form of business model in order to stay in the market and can compete with competitors..


The structural ability and magnetism of Fe@C/sub 20/, Fe@C/sub 20/H/sub 20/, and Fe/sub 2/@C/sub 30/ are studied using ab initio calculations. The binding energy and magnetic moment are obtained by solving the Kohn-Sham equations with localized orbital basis set. The values of the binding energy of each encapsulated Fe atom and Fe dimer are then used to calculate their chemical stability. The effects of the carbon encapsulation on the chemical stability and magnetic moment of the atom and dimer are investigated.


Postmodernism, as cultural thought in the modern western ,has influenced the animation profoundly.It includes deconstruction and construction dimensionality, which is reflected in the animation vividly.With the support of postmodernism, the foreign adult animation has relieved the forbidden region.The paper analyzes the postmodern features in the Animation Film, which will stand by the animation madein China.


This article analyzes the competitiveness of the regions of Georgia. The analysis is based on the model of comparative and absolute competitive advantage of the EU member states' regions, which is published every three years. The indicators used in the article correspond to the EU model, however, the difference in this case is only in the variables included in the indicators of the research. As a result of the article, the ranking of comparative as well as absolute evaluation of the competitive advantage of the regions of Georgia will be obtained.
Keywords: Regions of Georgia, Competitiveness, Regional Development, Public Policy, Comparative Analysis.


................................................................................................................................................................... viii List of Abbreviations Used .........................................................................................................................................ix Acknowledgements ...................................................................................................................................................... x Chapter 1: Introduction .............................................................................................................................................. 1 Background ............................................................................................................................................................... 1 Context and Significance of Study ............................................................................................................................ 1 Research Questions and Purpose ............................................................................................................................. 2 Study Design and Methods........................................................................................................................................ 2 Summary ................................................................................................................................................................... 3 Chapter 2: Literature Review ..................................................................................................................................... 5 Food Security ............................................................................................................................................................ 5 Impact of socio-economic status (SES). .............................................................................................................. 6 Chronic disease. ................................................................................................................................................... 6 Food Systems ............................................................................................................................................................ 7 Municipal food systems. ...................................................................................................................................... 7 Built environment. ............................................................................................................................................... 8 Mobile Food Markets (MFMs) ............................................................................................................................... 10 Health Promotion Relevance .................................................................................................................................. 13 Halifax Regional Municipality (HRM) Context ...................................................................................................... 15 Food insecurity and food systems. ..................................................................................................................... 15 Halifax's MFM. ................................................................................................................................................. 17 Partnerships and Participation ............................................................................................................................... 22 Methodology and theoretical approaches in partnership research. ..................................................................... 23 Partnership development, operation and sustainability. ..................................................................................... 25 Community partnerships. ................................................................................................................................... 26 MFM partnerships. ............................................................................................................................................. 29 Conclusion .............................................................................................................................................................. 29 Chapter 3: Methodology ........................................................................................................................................... 30 Case Study Method ................................................................................................................................................. 31 Conceptual Frameworks ......................................................................................................................................... 32 Feminist poststructuralism (FPS). ...................................................................................................................... 32 Social ecological model. .................................................................................................................................... 38 Study Population ..................................................................................................................................................... 39 Sample................................................................................................................................................................ 39 Recruitment. ....................................................................................................................................................... 40


In this paper, a new method of achieving anticipatory and complete synchronization through threshold coupling of two threshold controllers based chaotic oscillators is proposed. Until now, most of the synchronization of chaotic systems stated in the literature are based on common coupling methods like unidirectional and bidirectional coupling but rarely, cascaded and delay coupling. In this direction to add on a new kind of coupling known as threshold coupling is employed in this work. This coupled systems exhibit complete (CS) and anticipatory synchronizations (AS) for decreasing coupling resistor value without parameter mismatch and delay line. The proposed circuit is investigated experimentally and circuit behavior is also simulated using Multisim.


a national scale. Mass-merchandising techniques to sell political candidates began to develop. The practitioners of this industry have emerged from a variety of backgrounds: journalism, public relations, advertising, radio and television, and traditional political party or staff positions. And as a group they have come increasingly to perceive of themselves as skilled professionals. Rosenbloom says: &dquo;The most unanimous finding in this entire study revolves around the managers' self-image of professionalism.... They argue strongly that they bring scientific, or at least objective, views into an arena long dominated by myth and incompetence.&dquo; Rosenbloom sees a serious threat to democracy in this phenomenon. He writes: &dquo;A new political elite is developing at the very core of democracy that does not meet a crucial test, a relationship of responsibility to the people.... The campaign managers are increasingly accountable only to themselves and to their own vision of politics.&dquo; The lack of true accountability on the part of those who increasingly dominate our electoral processes is indeed a cause for concern in a democratic society.


Thank you for downloading the decline and fall of the us economy how liberals and conservatives both got it wrong. As you may know, people have look numerous times for their chosen novels like this the decline and fall of the us economy how liberals and conservatives both got it wrong, but end up in harmful downloads. Rather than reading a good book with a cup of tea in the afternoon, instead they juggled with some infectious bugs inside their desktop computer.


concepts Land as the object of property rights is different from most other types of property. In many cases there is not a 'logical' object. The object has to be defined, has to be legally constructed, and can change relatively easily (compare § 2.2.5 and § 3.2.4). The objects are separated by boundaries which define where one landowner's territory ends and the next begins. Even though there often is a reasonably high congruity between topographic boundary features and legal extent, there is no necessary identity between the topography of a parcel and the legal extent of that parcel. The extent and boundaries of land parcels are a matter of legal definition. (Burdon 1998: 152) Parcels and boundaries are abstract concepts. This makes a very large difference with most other types of geo-information, which depicts 'real life' geographical phenomenon. (compare van der Molen 2001: 15). Title plans and parcel maps are legal documents in a graphical form and not just another dataset for a geographical information system (GIS) (Burdon 1998: 154). Similarly the rights in land are abstract concepts. Property rights are an important example of institutions; humanly devised constraints that shape human interactions (see § 1.2.3). Rights in land are usually described in a complex system of land tenure. Through the abstract concept, land rights can grow into much more than a distribution mechanism for land use. The rights can be activated as capital, allowing inter alia for (cheaper) loans against collateral (see § 1.2.1). 78 SYSTEMS OF LAND REGISTRATION


Melittin, a natural antimicrobial peptide comprising 26 amino acid residues, can kill bacteria by inducing pores in cell membranes. Clinical applications of melittin as an antibiotic require a thorough understanding of its poration mechanism and mutations that enhance its antimicrobial activity. Previous experiments showed Melp5, a variant of melittin with five mutations, exhibits a higher poration ability. However, the mechanism of the enhanced poration ability is not fully understood. Here, we investigated the mechanism by comparing the poration of melittin and Melp5 using coarse-grained (CG) and all-atom (AA) molecular dynamics (MD) simulations. We observe that Melp5 is likely to form a pore with 5 peptides (pentameric), while melittin is likely to form a pore with 4 peptides (tetrameric). Our atomistic MD simulations show that the pentameric pore of Melp5 has a higher water permeability than the tetrameric pore of melittin. We also analyze the stability of the pores of melittin and Melp5 by calculating the interaction energies of the pores. In particular, we investigate the effects of mutant residues on pore stability by calculating electrostatic and LJ interactions. These results should provide insights on the enhanced poration ability of Melp5 and push it toward applications.


Buckwheat has gained scientists concern due to its nutritional and medicinal values in recent years, and many important bioactive compounds. The present study was performed to investigate the influence of the varietal performance and environmental conditions on the content of rutin and quercetin in Tartary buckwheat germplasm. A total of 44 foreign Tartary buckwheat germplasms were examined and compared their contents based on the collected countries, seed shape, and seed color. The highest number of germplasm (16) was found in ranged from 600 mg/100 g to 800 mg/100 g of rutin content. In case of quercetin content, the highest number of germplasm (19) was observed in ranged from 5 mg/100 g to 10 mg/100 g. However, the rutin content showed the highest value (1326.6 mg/100 g) from CBU408 and quercetin content showed the highest value (22.5 mg/100 g) from CBU456. The number of germplasm showed the highest value (23) in ranged from 3000 mg/100 g to 4000 mg/100 g of rutin content. The number of germplasm is the highest value (30) in ranged from 100 mg/100 g to 200 mg/100 g of quercetin content. When rutin and quercetin content in seed was compared according to collected countries, seed shape, and seed color respectively, no association was appeared with rutin and quercetin content. In sprout of whole Tartary buckwheat germplasm, mean of rutin content and quercetin content was 3362.9 mg/100 g and 14.2 mg/100 g respectively. In conclusion, the results observed from the present study suggest that highly rutin germplasm could be used more efficiently via breeding to develop a highly rutin content variety for using in sprout. No correlation was appeared in the case of quercetin. However, the quercetin content in sprout was 4~90 times more than seed. So, sprout could be used more efficiently than seed in the case of quercetin. Our results suggest that the varietal variation and qualitative characteristic differences of rutin and bioactive compounds may provide important nutrient sources and industrial application of Tartary buckwheat.


The ET(30) values in the core region of water/AOT/SC ethane micelles were determined for the first time as functions of pressure and water content of micelles (W0, [H2O]/[AOT]) at 310 K. The ET(30) values increased with increasing W0, but remained independent of pressure after system changed to a homogeneous micellar solution. The ET(30) values ranging from that observed in pure ethanol to 1,3-propanediol were obtained, with increasing W0 from 1 to 8.


While organizations are suggested to have been transformed by communication networks, the practices through which networks are realised and sustained are less well understood. The purpose of this p...


Objective: Aeromonas species (spp.) are emerging pathogen that is present in drinking water supplies which are a major reason for public health concern. Factors contributing to virulence include toxins, haemolysins, adhesins and various hydrolytic enzymes. The present study aimed at investigating the incidence of Aeromonas spp. and its virulence factors from environmental water bodies in Coimbatore. Methods: A total of 180 water samples were collected and screened for the presence of pathogenic Aeromonas spp. using starch ampicillin agar. The conventional method of identification might lead to misidentification of Aeromonas spp. thus molecular based identification using 16S rRNA gene was carried out followed by the identification of production of extracellular virulence factors like haemolysin, gelatinase, caseinase, lipase and DNase. Results: Incidence of Aeromonas in water sample was found to be 55% (100 positive isolates) which was also confirmed with the molecular identification. The isolates showed 60% of haemolytic activity,, 34% of gelatinase activity, 77% of caseinase, 52% of lipase and 48% of DNase activity. Conclusion: This study, thus, provides valuable information for the existence of pathogenic Aeromonas spp. in the environmental water bodies. Use of such water for domestic and commercial purpose might lead to the transfer of the pathogenic Aeromonas spp. Keywords: Aeromonas spp, Haemolysis, Caseinase, DNase, Gelatinase and lipase.


1. Introduction 2. What is literary fiction? 3. The fictional communication process 4. The cognitive and aesthetic dimensions of literature 5. The limits of the literary work 6. Intention and message 7. Problems related to the sender 8. The structure of the action 9. Selection 10. Voice 11. Viewpoint, focalization 12. Frequency 13. Order 14. Suspense 15. The functions of literary fiction 16. Evaluation 17. Conclusion BibliographyIndex


The present investigation "EMISSION OF CARBON DIOXIDE FROM MOTOR VEHICLES IN THE CITY OF LOJA" helps to improve air quality through the analysis of carbon dioxide emissions from motor vehicles in the city, as a result of a characterization of the urban vehicle fleet and the estimation of the level of emission of carbon dioxide (CO2) derived from motor vehicles.
To characterize the fleet was applied the technique of the survey focused primarily at the year and brand of vehicles, quantity and type of fuel, mileage, speed of movement, among other parameters. In the same way the vehicular capacity, in eight points higher flow in the urban area of the city, and on the basis of six categories of vehicles (motorcycles, cars, trucks, taxis, trucks and buses). It should be noted that information was also gathered from primary institutions, such as: the Municipal Unit of Land Transport Transit and Road Safety (UMTTTSV), Registration Center of vehicular Decentralized Autonomous Municipal Government of Loja, among others.
Obtained the information basis, it is calculating the amount of CO2 emission by applying the general formula generated by the Environmental Protection Agency of the United States (USEPA); resulting in the city of Loja the fleet emits 253.520 tonnes of CO2 a year, being the private transport category that contributes most (68.43%) to the total emission of the fleet in the city of Loja
The factors that determine the amount of CO2 emissions into the atmosphere, from the automotive transport land, are mainly: the number of vehicles and the hours of operation.
Keywords: Vehicular characterization, contamination by CO2, estimate of emissions from mobile sources.


The main difference between the case teaching method and the traditional one is the teaching body,the teaching way and the difference of the teaching material.The key factor includes the case types design and case librarys construction and its working program.By the way of practice,the case teaching method show advantage beyond compare.


Currently, the development of the police information system is an important field of the computer application studies, especially the development of automatic reasoning software of Steal Criminal Investigation.It faces a vast market for application and a considerable bright future. According to the software design principle-Fuzzy logical reasoning, with the combination of C++ procedure design language and V- Arity Prolong, we develop the automatic detective reasoning software tool, and accomplish the anticipative effect by mocks.


Currently in Brazil the ethnic groups are considered remaining of the communities of the quilombos racial, according to auto-attribution criteria, with proper trajectory, endowed with specific territorial relations, with swaggerer of related black ancestry with the resistance to the historical oppression suffered, to constructed concept on the basis of antropologico and sociological scientific knowledge, and fruit of ample quarrel technique, recognized for the Decree no 4,887/03 in its art. 2o. The Brazilian State, by means of the public agencies, works with this category, as well as all the society: the public press, agencies and agent politicians. Today if quilombola speaks of quilombos as a legal-constitutional assignment for delimitation of the territory. Therefore, one understands that the elaboration of deepened study is excellent that supports the elements that had constituted the concept of quilombo.


Since the breakup of the USSR, trade has contracted sharply for the fifteen new independent states, both with each other and with the rest of the world. This paper analyzes the factors that contributed to the decline and recommends approaches that will enable these countries to restore trade relations with each other and to integrate their economies effectively with the broader international economy. For governments of the new independent states, the paper recommends actions to: (a) phase out remaining price controls and related export restraints and import subsidies; (b) strengthen competitive forces in trade by terminating state trading, promoting entry of private firms, and encouraging enterprise-to-enterprise trade; (c) improve the institutional infrastructure in support of trade, especially the domestic and international payments system; and (d) increase intergovernmental cooperation in addressing trade and payments issues. For the international community, the paper also recommends support of these countries' efforts through actions to: (a) provide technical assistance and policy advice for strengthening the institutional capabilities of these countries to compete internationally; and (b) improve access for exports of the new independent states to markets in developed industrial countries by reducing these countries' trade barriers on imports of manufactures and agricultural products.


I had a strange dream the other night. Two elderly gentlemen were sitting on a park bench engaged in a philosophical discussion. I came on the scene long after the discussion between the two had started. I started taking notes, but the notes were incomplete. Suddenly the two men departed from the scene and I had nothing to go on but my partial rendering of a discussion that I had come upon long after it had started. So, I was faced with the decision whether to discard my notes altogether or reconstruct the debate. On the one side, if I were to discard my notes, I would lose for myself what I thought would be an enlightening and intellectually crucial discussion. On the other side, if I were to reconstruct their discussion from my incomplete notes, I would create a somewhat fictional and false account of their discussion. I chose the latter course of action: perhaps my misinterpretation might shed some understanding on a rather complex but fundamental problem.


Many important problems in Computational Geometry needs to perform some kind of angle processing. The Polar Diagram [4] is a locus approach for problems processing angles. Using this structure as preprocessing, one can eliminate exhaustive searches to flnd objects with smallest angle. Handling data in change is a signiflcant concept in Computer Science. One of the design and analysis tools used in the modeling of moving geometric objects is the kinetic data structure (or KDS) framework Kinetic Data Structure is a framework for maintaining a certain attribute of a set of objects while moving in a continuous manner. In this paper, we use the notion of kinetic data structure to model the dynamic case of the Polar Diagram, i.e we maintain the the Polar Diagram of a set of continuously moving objects in the scene. We show that our proposed structure meets the main criteria of a good KDS.


Social-based recommendation systems exploit the selections of friends to combat the data sparsity on user preferences, and improve the recommendation accuracy of the collaborative filtering strategy. The main challenge is to capture and weigh friends' preferences, as in practice they do necessarily match. In this paper, we propose a Neural Attention mechanism for Social collaborative filtering, namely NAS. We design a neural architecture, to carefully compute the non-linearity in friends' preferences by taking into account the social latent effects of friends on user behavior. In addition, we introduce a social behavioral attention mechanism to adaptively weigh the influence of friends on user preferences and consequently generate accurate recommendations. Our experiments on publicly available datasets demonstrate the effectiveness of the proposed NAS model over other state-of-the-art methods. Furthermore, we study the effect of the proposed social behavioral attention mechanism and show that it is a key factor to our model's performance.


Cartap is among the most popular pesticides that are widely used to boost food production, however, its residues pose a great threat to human health and the environment. We presented simple and effective colorimetric sensor based on aggregation of gold nanoparticles (AuNPs) with appropriate diameter and fluorescent sensor via inner filter effect (IFE) of AuNPs on cadmium telluride quantum dots (CdTe QDs), respectively. Firstly, effect of diameter of AuNPs was investigated and the results indicated that AuNPs with diameter of 13nm (AuNPs13nm) showed better sensitivity toward cartap. Thus, AuNPs13nm was chosen for colorimetric and fluorescent cartap assay. On one hand, mercaptoacetic acid (MA) was functionalized on AuNPs13nm for the improvement of anti-disturbance ability for discrimination study. A decent linear relationship for cartap was obtained in the range from 1μM to 50μM with detection limit of 1.32μM for colorimetric readout; on the other hand, fluorescent sensor based on AuNPs13nm displayed excell...


Cesarean section (Sectio Caesarea) is an attempt to remove the fetus through surgery on the abdominal wall and uterus. The use of inappropriate prophylactic antibiotics will lead to infection and resistance. The purpose of this study was to determine prophylactic antibiotic use, in cesarean section patients, to know prophylactic antibiotic use in cesarean section patients in accordance with antibiotic use guidelines (PPAB) Ulin Hospital in 2017, to know prophylactic antibiotic use in cesarean section patients in accordance with Permenkes RI Number 2406 / PER / XII / 2011. This research is a non-experimental type of descriptive study retrospectively by taking medical record data of cesarean section patients at Ulin Banjarmasin Hospital in 2017 with saturated sampling method, obtained a population of 99 medical records of cesarean section with a total sample of 99 medical records. The use of prophylactic antibiotics in Ulin Banjarmasin Public Hospital is a class of third generation cephalosporins namely ceftriaxone and cefotaxime with doses of 1-2 grams / day and duration of 3-5 days. Comparison of the percentage of prophylactic antibiotic use with the guidelines for drug use in Ulin Hospital in Banjarmasin in 2017 is the name and class of 100% is appropriate and 0% is not appropriate, the dose is 100% appropriate and 0% is not appropriate, the duration of administration is 69.70% is appropriate and 30.30% is not corresponding. Comparison of the percentage of prophylactic antibiotic use with Permenkes RI Number 2406 / PER / XII / 2011 is the name and class of 0% is appropriate and 100% is not appropriate, the dose is 0% is appropriate and 100% is not appropriate, the duration of giving 0% is appropriate and 100 % it is not in accordance with.


3-Oxo-1, 2, 3, 4-tetrahydro-1-naphthoic acid obtained by reduction of 3-methoxy-1-naphthoic acid with sodium amalgam was condensed with N-methyl-N-acetylhydrazine to give the corresponding hydrazone (VIII). VIII was submitted to catalytic reduction over Adams catalyst, methylation with formic acid-formalin, hydrolysis with hydrochloric acid, esterification with methanol and intramolecular cyclization to afford 3, 4-dimethyl-3, 4, 5, 6-tetrahydro-1, 5-methanobenzo [e][1, 2] diazocin-2(1H)-one(XII). Treatment of XII with lithium aluminum hydride gave an abnormally cleft product, 4-methyl-5, 6-dihydro-1H, 4H-1.5-methanobenzo [e][1, 2] diazocine (XVII). XVII was reduced with lithium aluminum hydrode to give 4-methyl-1, 2, 3, 4, 5, 6-hexahydro-1, 5-methanobenzo-[e][1, 2] diazocine (XVIII). Structures of XII, XVII and XVIII were confirmed by chemical as well as spectral methods.


ABSTRACT Although much has been written about the ideology of Laurent Gbagbo's Front Populaire Ivoirien in Côte d'Ivoire and its impact on the Ivorian politico-military crisis, little attention has been paid to the ubiquitous role of the law in the discourse and political strategy of the pro-Gbagbo elite. The Ivorian case may provide important insights about the connection between ultranationalist ideology and a legalist, formalist conception of democracy and national sovereignty. The article analyses the circumstances of the emergence of 'legalist nationalism' in Côte d'Ivoire by looking at key episodes of the Ivorian transition between 2002 and 2012. The article discusses the relevance of Pierre Englebert's concept of 'legal command' and the turbulences of democratic transitions in accounting for the prominence of legalism in Ivorian politics. It explores the implications of the Ivorian case for understanding the connection between law and politics in Africa.


Given C*-algebras A and B acting cyclically on Hilbert spaces H and K, respectively, we characterize completely isometric A,B-bimodule maps from B(K,H) into operator A,B-bimodules. We determine cogenerators in some classes of operator bimodules. For an injective cogenerator X in a suitable category of operator A,B-bimodules we show: if A, regarded as a C*-subalgebra of Al(X) (adjointable left multipliers on X), is equal to its relative double commutant in Al(X), then A must be a W*-algebra.


The device comprises at least one element is connectable to a hot fluid circuit and in turn flows in the operation of the hot fluid. This element (2) consists of an extruded profile made of aluminum or aluminum alloy having internal longitudinal channels (5, 6) which are flowed through by the hot fluid. The profile element (2) is mounted between end pieces and intermediate pieces for connecting this element to the hot fluid circuit or for connection of such profiled elements to each other. The apparatus is used for heating the passenger compartment of vehicles for common passenger transport.


This analysis of upstream dam flooding leads the staff to conclude that the issue deserves further evaluation to determine what else the NRC might need to do. No immediate safety concerns were identified during the preparation of the analysis. The NRC conducted this analysis as part of the third, or screening, stage of the agency's five-stage Generic Issues (GI) Program. The NRC staff conducts this screening solely to determine, based on readily available information, whether an issue requires more detailed evaluation within the GI program. This analysis says nothing about whether existing nuclear power plant (NPP) licensing bases, design requirements, or regulations are adequate, nor whether plants comply with those standards. Although the analysis discusses some current regulatory actions regarding flooding issues at specific plant sites, it is silent regarding the performance of those or any other licensees. Plant performance is judged by other regulatory processes, primarily the Reactor Oversight Process (ROP). Finally, this analysis reaches no regulatory conclusion about dam reliability or the likelihood of beyond-design-basis failure events. Those decisions are addressed in subsequent stages of the GI Program to determine the need for, and strength of, additional NRC regulatory actions.


In this short article I explore the display of waxworks by modeller Joseph Towne (1806–1879) at the Gordon Museum at King's College London. Using a framework of visibility, I consider how the dichotomy of seen and unseen is interwoven in the representation of the body in Towne's work. The previously hidden world of the internal structure of the human form is depicted with brutal accuracy in Towne's large-scale anatomical waxes, immortalizing the encounter between anatomist and cadaver in the nineteenth-century hospital. This is contrasted with the very visible world of dermatology, a discipline founded on the ability to read the signs of disease manifest on the skin. In his realistic renderings of skin conditions, Towne has unexpectedly captured the faces of the hospital's nineteenth-century patients. I contend that the collection of dermatological moulages allows the historian to glimpse the diversity of the patient population of the mid-Victorian hospital, a testament to the variety of bodies which came under the physician's gaze. The Gordon Museum at King's College London is open by appointment to medical students, practitioners, and historians of medicine.


It is well known that the "world's oldest profession" was widespread across all of the Old World and that almost every pre-modern city had one or more brothels or "bathing houses", even though official public opinion and governments may not have encouraged this. In actuality, such establishments were a part of the local offer of amusements, especially in market towns and harbors which were frequently visited by outsiders. This contribution focuses one of these establishments – the official city brothel, its personnel and clientele using medieval Dubrovnik as a case study. Moreover, considering how even today public opinion is sharply divided on the issue of prostitution, investigating its medieval past also shows a wide range of conflicting


A kind of Radioactivity Monitor System with Vehicle Contour Acquisition Module based on Optical Screen is developed.The system can reduce the shielding effect caused by the passing vehicles,so that the alarming sensitivity is improved.This paper introduces the work situation of the system and preliminary experimental results.