David Flemming was a member of the second last graduating class of Saint Mary's High School in 1962, and is also an alumni of Saint Mary's University. David helped create the exhibits and the memorial plaque for the 1988 reunion commemorating 25 years since the closing of the Saint Mary's High School. He was also the Chair of the Saint Mary's Sport Hall of Fame from 1995 to 2000.


Thank You, Tom. Mr. President, members of the Society, ladies and gentlemen: I am deeply honored to have been selected as the Ralph W. Marsden Award recipient for 1999. This award has additional significance for me as Ralph gave me my first job in the mining industry—a memorable summer as a mapping party chief on the Negaunee Iron Range for the Oliver Mining Company division of U.S. Steel. So I have special memories of Ralph and the support that he and the others with whom I worked gave me that summer.

If someone would have told me when I accepted the position of Executive Secretary in 1992 that in eight years we would have achieved half the accomplishments mentioned by Tom, I probably would have thought that person was from another planet—or had been using some mind-altering substance. Those accomplishments, however, represent the volunteer efforts of many, and clearly illustrate the power of voluntarism. The Society has a long and strong history of voluntarism. This is well-documented in the Society's history volume, 75 Years of Progress: 1920 –1995 . As far as I know, no SEG officer ever received direct compensation, that is, a salary, for services performed on behalf of the Society. We are where we are today because of the actions and services—all voluntary—of our predecessors.

As Society members, we are, and have been, bound by our common, deep-seated interest in mineral resources and ore deposits—whether from the aspect of scientific research, in which we have a proven track record of excellence (our Penrose Medalist today, Julian Hemley, is a terrific example), or the application …


The present work extends the semi-integrated method proposed by Antuono and Brocchini ["Beyond Boussinesq-type equations: Semi-integrated models for coastal dynamics," Phys. Fluids 25(1), 016603 (2013)], which comprises a subset of depth-averaged equations (similar to Boussinesq-like models) and a Poisson equation that accounts for vertical dynamics. Here, the subset of depth-averaged equations has been reshaped in a conservative-like form and both the Poisson equation formulations proposed by Antuono and Brocchini ["Beyond Boussinesq-type equations: Semi-integrated models for coastal dynamics," Phys. Fluids 25(1), 016603 (2013)] are investigated: the former uses the vertical velocity component (formulation A) and the latter a specific depth semi-averaged variable, ϒ (formulation B). Our analyses reveal that formulation A is prone to instabilities as wave nonlinearity increases. On the contrary, formulation B allows an accurate, robust numerical implementation. Test cases derived from the scientific liter...


With the rapid evolution in the mobile computing field, the new alternatives are derived in which mobile devices form a self-creating, self-administering and self-organising wireless networks. Mobile Ad Hoc Network (MANET) is one such arbitrary network in which all the nodes are mobile and consists of limited battery power and channel bandwidth. These Ad Hoc networks are often used in emergency situations. The frequent change in topology leads to more consumption of energy, therefore saving power in such situations is of prime importance. In this paper, we will try to make some improvements in the already exciting energy efficient routing protocols in order to get better results. We will find minimum distance from source to destination by changing the route request phase. In this way, the energy of nodes with not suffers from inefficiency. Keywords: AODV, Mobile Ad hoc Networks, Energy Efficiency and Routing.


In this paper, we defined the conceptions of consistent entropy, diverse entropy, inverse entropy, and connective entropy etc. Which are important conceptions in uncertain theory-SPA theory. Furthermore, we study its practical meaning and obtain its measurable formula. Applying this formula into "Investment Environment", we analyze it with qualitative and quantitative and put forward perfect project' measure, As a result, we can choose the better by calculating the infinitesimal entropy of this system. We get decision analysis results based on 17 zones' practical examples of investment environment in Henan province.


Abstract In this paper, a 3d exploration algorithm is presented which always keeps the robots within communication range of each other. The exploration is integrated into a control infrastructure containing sensors, mapping, navigation, and control of actuators. The algorithm is tested in a high fidelity simulator which takes into account the dynamics of the robot, and simulates the required sensors. Furthermore, we test the effect of communication range, and sensor range on the exploration.


In Ghirardato, Macheroni and MArcinaccri (GMM) propose a method for distinguishing between percieved ambiguity and the decision-maker's reaction to it. They study a general class of preferences which includes CEU and a-MEU and axiomatise a subclass of a-MEU preferences. We show that for Hurwicz preferences the proposed measure of ambiguity depends on parameters which intuitively reflect ambiguity-attitude. Furthermore, any a-MEU preferences which satisfy the CEU axioms, satisfy GMM's axioms if and only if a = 0 or 1, that is, the capacity must be convex or concave.


This issue of the "Nursing Clinics of North America", Guest Edited by Diane B. Monsivais, PhD, CRRN, will cover Culturally Competent Care topics including such articles as The Clinically Relevant Continuum Model; Culturally Competent Care for Families with Burn Injury, Chronic Pain, End Stage Renal Disease and Parkinson's Disease; an Innovative Model for Teaching Culturally Competent Care; Acculturation, Somatization of Depression, and Function in an Hispanic American Population; Culture of the Colonias/Constructing the Meaning of Asthma in the Colonias; Genetics and its Relevance on Culture and Ethnicity; and Creating Culturally Appropriate Language Translation.


Abstract Instead of writing equations which when solved yield the response of a vehicle to an input such as the front wheel steer angle, one can often invert the equations so that a response quantity is specified as an input and a new set of equations is solved yielding the steer angle required as an output. Using these equations one can discover the input steer angle a driver would need to impose in order to accomplish a specific maneuver for various vehicles. It is shown that there are many possible inverse equation sets and that the eigenvalues of the inverse equations are hard to interpret since they may have little to do with the vehicle parameters. The linear single-input single-output case is studied first to fix ideas using a simple example. For the bicycle model vehicle, it is shown that any vehicle may have unstable inverse equations depending upon the response quantity used. Extensions to nonlinear and multiple-input multiple output systems are discussed.


Diabetic complications are detrimental problem and the most prevalent cause of morbidity and mortality among the people with Type 2 diabetes mellitus (Morrish et al., 2001). Type 2 diabetes mellitus is a metabolic disease characterized by hyperglycemia resulting from declining beta cell function and insulin resistance (American Diabetes Association, 2011). India has the highest population suffering from diabetes across the world (Kaveeshwar and Cornwall J, 2014). The prevalence of diabetes was 415 million in 2015 and expected to rise to 642 million by 2040 with a maximum increase in India (Whiting et al., 2011). Epidemiological studies demonstrated, 85% of diabetics in the world are suffering from diabetic dyslipidemia. The characteristic features of diabetic dyslipidemia are a high plasma triglyceride (TG) levels, low high-density lipoprotein cholesterol (HDL-C) levels and a high proportion of small dense low-density lipoprotein cholesterol (Mooradian, 2009). Despite numerous antidiabetic drugs are identified, the prominent combination therapy for management of diabetes is still unavailable. The combination therapy based on the rationale with the multitargeted approach has a vital role in the management of diabetes and related complications. Therefore, there is need to identify the combination that improves glycemic and lipid control and reduce the risk of life threatening complications.


Predicting the behavior of surrounding traffic participants is crucial for advanced driver assistance systems and autonomous driving. Most researchers however do not consider contextual knowledge when predicting vehicle motion. Extending former studies, we investigate how predictions are affected by external conditions. To do so, we categorize different kinds of contextual information and provide a carefully chosen definition as well as examples for external conditions. More precisely, we investigate how a state-of-the-art approach for lateral motion prediction is influenced by one selected external condition, namely the traffic density. Our investigations demonstrate that this kind of information is highly relevant in order to improve the performance of prediction algorithms. Therefore, this study constitutes the first step towards the integration of such information into automated vehicles. Moreover, our motion prediction approach is evaluated based on the public highD data set showing a maneuver prediction performance with areas under the ROC curve above 97% and a median lateral prediction error of only 0. 18m on a prediction horizon of 5s.


AbstractAfter reviewing people's participation and gender in development theatre in general, the role of development theatre is described in five water and sanitation programmes in India. The author concludes that collective action and behavioural change require a different type of theatre than now practised in some of these programmes. A gender perspective, present in some cases, is needed consistently to avoid a situation whereby performing arts confirm and reinforce existing gender inequalities. Empirical research is recommended for further insight into gender aspects of contents, access, and impacts.


For a class of nonlinear control system under the network environment, both delay and packed dropout in transmission are addressed. A T-S fuzzy model is employed to represent the nonlinear controlled plant. By using appreciate Lyapunov-Krasovskii function, the robust integrality sufficient conditions of systems with failures of actuator or sensor is analyzed based on delay-dependent approach, and the fault-tolerant control gain can be obtained. The lower bound of the time-delay is introduced in the function, and the free variables which integral inequalities bring are taken advantage of. It guaranteed that does not carry on magnifying or ignoring and the model transformation to integral inequalities, then a less conservative results is obtained. Finally, an example is used to illustrate the effectiveness and feasibility of proposed approach based on OPC technology.


Malaysian traditional furniture has its own characteristics and values. Despite all of the discrepancies in determining the agreed form of 'traditional furniture' several opinions and ideas should be analyzed thoroughly. This is because there is no standard guidelines or rule to be used as a standard scale in identifying what is 'Malay Traditional Furniture'. Within that study the form of approach should be look as furniture design in the general term. 'Traditional' as described by the Oxford Dictionary stated as something to be based on or obtained by tradition. 1 'Furniture' then was described as moveable contents of building or room, accessories far example handles or locks on door. However from the term stated by the Dept of Etanology, the meaning of traditional furniture must comply to any furniture made in the traditional style and carves with the traditional motifs without changing the category of design.


Introduc on S gma of people towards mental illness is s ll prevailing in our country due to lack of awareness. General public's view about mental illness remains largely unfavourable. The topic of mental illness itself evokes a feeling of fear, embarrassment or even disgust fostering nega ve a tudes towards mental illness and mentally ill people. There is paucity of ar cles on this topic from our country. Objec ve To inves gate college students' s gma towards mental illness and factors associated with the s gma. Methodology This prospec ve study was done in College students studying Bachelors of Science. A randomly selected sample of students were explained and asked to fill two forms: First containing socio-demographic data and Second Discrimina on Devalua on scale (D-D scale). Data collected were analyzed with SPSS so ware. Descrip ve analysis and Chi-square tests were done. P value less than 0.05 was considered significant. Results There were 78 students included in the study among which 43.6% (n = 34) had high level of s gma towards mental health. This s gma was not significantly associated with age, gender, year of study among the gradua ng students, rural or urban background, history of mental illness, or knowing someone with mental illness. Conclusion S gma towards mental illness is common even in the educated group of people in the country. With the same level of educa on, s gma to mental health is not significantly associated with other demographic variables.


: The Satahi Suga Suga Savings and Loans Cooperative operates in the field of lending and borrowing funds. In other words, managing funds as well as possible is the main focus of the activities of the Satahi Suga Suga Savings and Loans Cooperative, because to assess the effectiveness of managing its funds the Satahi Suga Suga Savings and Loans Cooperative cannot use one financial measure, namely profitability alone, but must also involve evaluating various aspects. The research aims to determine the effectiveness of managing the funds of the Satahi Suga Suga Savings and Loans Cooperative for 2021 based on the Regulation of the Minister of State for Cooperatives and Small and Medium Enterprises of the Republic of Indonesia Number 20/Per/M. KUKM/XI/2008 concerning aspects of capital, aspects of productive asset quality, aspects of liquidity, aspects of independence and growth. The subject of this research is the Satahi Suga Suga Savings and Loans Cooperative where the object of evaluation is the management of KSP Satahi Suga Suga funds. Data analysis techniques in this study used descriptive analysis. In this study data was collected through the documentation method. From the results of the study, the soundness level of cooperatives is included in the "Quite Effective" category with a total score of 56.75 out of a total score of 100. If assessed from guidelines for evaluating the effectiveness of fund management, it has a score of 56.75 which is in the total weighted score of 40-60 with the predicate less effective.


Abstract Tensile testing of two samples of 3·5Ni-Cr-Mo-V steel, differing significantly in carbon and manganese content and hence in strength after heat treatment, has been carried out in a gaseous hydrogen environment. The ductility observed was found to be dependent on both strength level and heat treatment. Treatments that produced 0·2% flow strength levels below about 1700 MN/m2 appeared to induce resistance to embrittlement by gaseous hydrogen, except where heat treatments were carried out in what appeared to be a critical range for temper embrittlement. A tendency towards temper brittleness resulted in a ductility trough around 400°C that was greatly accentuated by testing in hydrogen. This appears to substantiate a cooperative action of temper embrittlement and hydrogen embrittlement. Very different failure modes are associated with the two conditions giving rise to lowstrain, hydrogen-induced failures: quenched or lightly tempered structures give rise to quasi-cleavage, whereas materials tempered ...


In this paper, velocity estimation method for caster odometers is proposed. Caster odometer is a sensor of travel distance and attitude angle using caster mechanism that has two-degree of rotational freedoms. We calculate velocities of a vehicle utilizing the output measured by caster odometers, however, the caster mechanism has nonlinearity component. To deal with the nonlinearity of the caster mechanism, a velocity is estimated by the extended Kalman filter. It is expected to reduce the effect of noise with higher precision than conventional methods (approximated differentiation, extended Luenberger observer). We confirm the accuracy of the proposed estimation by comparing to the conventional method in numerical simulation.


We propose a scheme for generating vibrational pair coherent states of the motion of an ion in a two-dimensional trap. In our scheme, the trapped ion is excited bichromatically by three laser beams along different directions in the {ital X}-{ital Y} plane of the ion trap. We show that if the initial vibrational state is given by a two-mode Fock state, the final steady state, indicated by the extinction of the fluorescence emitted by the ion, is a pure state. The motional state of the ion in the equilibrium realizes that of the highly correlated pair coherent state. {copyright} {ital 1996 The American Physical Society.}


Electrostatic sensors are broadly applied to measure velocity of solid particles in many industries because controlling the velocity particles improves product quality and process efficiency. These sensors are selected due to their robust design and being economically viable. Optimization of different electrode sizes and shapes of these sensors is required to find the ideal electrodes associated with maximum spatial sensitivity and minimum statistical error. Uniform spatial sensitivity is a crucial factor because it would lead to increase similarity between the measured correlation velocity and true mean particle velocity. This thesis proposes a new method to optimize different parameters of electrodes for electrostatic sensors. This technique identified characteristics of the electrostatic sensor in a MATLAB code called Particle Swarm Optimization (PSO). A mathematical model of various electrodes to compute spatial sensitivity and statistical error was applied to extract geometric size information of electrodes to detect suitable equations. To validate the proposed method, different values of electrode designs were applied in experimental tests conducted in a laboratory to measure the velocity of solid particles. The experimental results were optimized through Response Surface Methodology (RSM), an optimization technique for experimentation. The optimized results showed that spatial sensitivity of circular-ring electrode is more uniform in comparison to the other electrodes. The optimal length of circular-ring electrode was between 0.577 cm and 0.600 cm. In addition, the best thickness for the electrodes was between 0.475 cm and 0.500 cm. A close agreement between optimization and experimentation verifies that the proposed method is feasible to optimize physical sizes of electrostatic sensor electrodes. These results provide a significant basis of the effect of geometric dimensions on the sensing characteristics of electrostatic sensors.


A major obstacle in applying orthogonal frequency-division multiplexing (OFDM) in wireless local networks is the need for a highly linear and efficient radio frequency power amplifier. The strong fluctuated envelope of an OFDM signal makes it difficult to build this kind of power amplifier. In this paper, we consider the use of the envelope elimination and restoration method for OFDM power amplification and evaluate its performance tradeoffs. The results are compared to the performance of a linear power amplifier with different power backoffs. In addition, as the envelope of an OFDM signal is concentrated at low level, the average output power is low when a low supply voltage power amplifier is used. Simulation is done to show that the signal power (or signal-to-noise ratio for fixed noise level) can be traded off with clipping level for optimum bit-error-rate without increasing power supply voltage.


In this paper, an inventory model is developed to maximize the total average profit. The rate of deterioration is taken as fixed. The effect of inflation is also considered in this present paper. The demand rate is assumed to be price and stock dependent. Shortages are allowed and partially backlogged. The backlogging rate is assumed to be dependent on weighting time. Numerical examples and sensitivity analysis are presented to illustrate the result of the proposed model.


On 27 February 2008, the Commission announced that it had imposed a penalty payment of € 899 million on Microsoft for its alleged failure to comply with obligations contained in the Commission's…


The replik to the author of the publication: "In response to prof. Józef Piłatowicz". The text was published in the 4th issue of the journal "Historia i Świat" in 2015.


This research was carried out to determine the best fitting model to the growth curve of female Malya lambs from weaning to pre-mating period. To achieve this aim, live weights of 23 weaned female Malya lambs divided into two different groups (n:11 heads; 10 kg 0.93) for group I and (R2>0.91) for group II by the all models. The highest R2 values were determined from Cubic, Quadratic and Gompertz models. The models except for LM have low MSPE and RESC values. The lowest MSPE and RESC values were predicted in CM and GM for two groups. When the combination of these values for both groups is taken into consideration, it is seen that the best fit to growth curves of female Malya lambs was acquired with CM, which was niggardly better than that of QM and GM, and LM fitted worst. In terms of model selection criteria, these three models were found to be mathematically adequate for describing the growth in female Malya lambs.


In the case of the treatment of low back pain, the lumbar corset which is the orthotic therapy is mainly used. However, there is a problem that the trunk muscle group is not used continuously by wearing the conventional lumbar corset for a long time, and muscle decline may occur. In this research, we propose an intelligent pneumatic corset that detects the forward bending posture with a sensor and automatically drives the soft actuator according to the attitude angle. It detects a forward-leaning posture in which the burden on the lumbar region increases, and automatically pressurizes the soft actuator. And, in the corset developed so far, the effect of supporting the muscle of the lumbar region was expected by compressing the abdomen and increasing abdominal pressure. In this paper, the operation support method by the restorative force when the soft actuator is deformed and the design of the intelligent pneumatic corset with built-in them are described.


In this paper, we give a description of polynomial functors from ( finitely generated free) groups to abelian groups in terms of non-linear Mackey functors generalizing those given in a paper of Baues-Dreckmann-Franjou-Pirashvili published in 2001. This description is a consequence of our two main results: a description of functors from (fi nitely generated free) P-algebras (for P a set-operad) to abelian groups in terms of non-linear Mackey functors and the isomorphism between polynomial functors on ( finitely generated free) monoids and those on ( finitely generated free) groups. Polynomial functors from ( finitely generated free) P-algebras to abelian groups and from ( finitely generated free) groups to abelian groups are described explicitely by their cross-e ffects and maps relating them which satisfy a list of relations.


Summary The nomenclatural history of Carex fuliginosa Schkr. and its subsp. Carex misandra R. Br. is recalled. Carex fuliginosa is found in some places in the central parts of the Alps and Carpathian mountains. Its localisation in France is discussed. Carex misandra has a strict periarctic distribution. Morphological features of C. fuliginosa are described and compared to closely related species.


AbstractAccurate knowledge of the impact of internal atmospheric variability is required for the detection and attribution of climate change and for interpreting glacier records. However, current knowledge of such impacts in high-mountain regions is largely based on statistical methods, as the observational data required for process-based assessments are often spatially or temporally deficient. Using a case study of Kilimanjaro, 12 years of convection-permitting atmospheric modeling are combined with an 8-yr observational record to evaluate the impact of climate oscillations on recent high-altitude atmospheric variability during the short rains (the secondary rain season in the region). The focus is on two modes that have a well-established relationship with precipitation during this season, El Nino–Southern Oscillation and the Indian Ocean zonal mode, and demonstrate their strong association with local and mesoscale conditions at Kilimanjaro. Both oscillations correlate positively with humidity fluctuati...


Dr. Herrnheiser, consultant radiologist to the Connaught and the St. Margaret's Hospitals, London, and a former Professor of Radiology at the German University of Prague, died suddenly on May 13. He was born in 1890 in Prague, and studied medicine at the University Medical School there, and also at Munich. After graduating M.D. in 1914 he spent seven years in post-graduate work in Prague; at the morbid anatomy department under Ghon and at the department of internal medicine under Jaksch v. Wartenhorst. In 1920, on the advice of Jaksch, he decided to train in radiology, and he joined the radiological department of the University Medical School in Vienna under Holzknecht. Five years later he returned to Prague as Dozent in radiology to the German University Medical School, and in 1931 he was appointed to the chair of radiology.


The Upper Muschelkalk sedimentary record constitutes a major transgressive pulse of north‐eastern Iberia during the Ladinian. This record is arranged in two transgressive–regressive (T–R) sequences formed by two stepped microbial‐dominated carbonate ramp systems where accommodation was mainly controlled by extensional faults. This study seeks to gain new insights into how the evolution of syn‐rift subsidence controls the creation of accommodation space, the depositional styles and, especially, the palaeogeographical domains where specific microbialites developed (thrombolites and stromatolites). Thrombolite bodies (at least 40 m thick) display two types of architecture, biostromal and mud‐mounded and stromatolite bodies (at least 7 m thick) consist of tabular and domed, head‐shaped morphologies. Domed and mounded forms are usually developed during stages of increasing accommodation rates, low‐to flat‐nelief forms tend to grow in association with periods of low accommodation rates. A sea‐level fall of at least 50 m occurred at the end of the Early Ladinian leaving the platform subaerially exposed. As a result, a prominent karst with significant erosional incisions and profuse collapse breccia fillings was formed in the inner and middle ramp settings. The resultant subaerial unconformity bounds T–R sequences 1 and 2. Subsidence curves display two stages of rapid/decelerated total subsidence, constituting two discrete rift/post‐rift pulses in the large Triassic rifting period: (i) Buntsandstein – Middle Muschelkalk, and (ii) Late Muschelkalk – Imon Formation (Rhaetian). The second pulse is characterized by a rapid syn‐rift subsidence during the Late Muschelkalk, and a decelerated post‐rift subsidence throughout the deposition of Keuper facies and Imon Formation. The Late Muschelkalk rapid syn‐rift pulse of total subsidence produces gains in accommodation, which controls the development of the stromatolites and thrombolites (biostromes and mud‐mounds).


This paper probes the nanoparticle (NP) interaction with hydrogels using electroacoustic spectroscopy at MHz frequencies. We measured dynamic electrophoretic mobility spectra of silica NPs in polyacrylamide gels for a variety of NP sizes and gel concentrations. The spectra are exquisitely sensitive to NP entrapment, size, and charge as well as to gel rheology and gelation kinetics. For NPs that are large compared to the gel mesh size, many of these influences can be quantified using electrokinetic theory, which furnishes the apparent NP ζ-potential and a complex gel shear modulus at MHz frequencies. The methodology provides new insights into the NP–hydrogel interaction, since it noninvasively probes the nanostructure and the combined influences of particle and gel properties. Electroacoustic spectroscopy may therefore be a valuable new tool for characterizing soft nanocomposites—one that complements other noninvasive methods, such as bulk rheometry and microrheology.


Background: Postoperative CSF leakage is one of the most common complications after pituitary adenoma resection by endoscopic endonasal transsphenoidal approach (0.6%–3.5%). Sellar reconstruction has been postulated as a crucial step in this approach to overcome such complications. Aim of the study: to evaluate the efficacy and safety of different grafting types and factors that determine which sellar repair is needed according to the size of arachnoid defect or CSF flow. Patients and Methods: Retrospective study included 32 patients at Al azhar university hospitals who underwent endoscopic endonasal sellar repair (EER) with different grafting types after pituitary surgery. 14 patients repair with fascia lata graft, 12 patients with dural substitute (Duragen Integra LifeSciences Corp, USA) and 6 patients vascularized nasoseptal flap. Results: The mean age was (33.68 ± 10.2) years, with (59.4%) females and (40.6%) males. Regarding post-operative complications; (21.9%) of patients had CSF leakage, (6.2%) had epistaxis and sinusitis, (9.4%) had pneumocephalus, and the overall complications rate was (34.4%), with success rate (78.1%), and failure rate (21.9%). On comparing the 3 grpups, seven patients (21.9%) had repair failure and required reoperation for repair of persistent CSF leak and need recurrent sellar repair, 4 patients (12.5%) from fascia lata group and 3 patients (9.3%) from dural substitute group. Conclusion: vascularized nasoseptal flap is effective as regards success rate, repair failure and complications rates. The other types (fascia lata and dural substitute) are effective and safe with low CSF leakage rates.


This paper presents the results of research on the energetic use of self-combusted hemp pellets and co-firing with pine pellets. The tests were carried out with the use of a boiler equipped with a Lester Projekt Company gasifying burner and an automatic fuel feeding system. The boiler is equipped with an additional heat exchanger that enables the simulation of any heat load. The experimental stand so built guaranteed to obtain results adequate to the real operating conditions. The research material consisted of pellets made of waste biomass of the Futura 75 sowing hemp and pine sawdust pellets. The experiment was carried out in five proportions by mass of mixtures of both fuels (C-hemp, P-pine): 0:100 (P100), 25:75 (C25/P75), 50:50 (C50/P50), 75:25 (C75/P25), 100:0 (C100). For each variant, the following were determined: effective boiler power, boiler energy balance, boiler energy efficiency, the volumetric composition of flue gas (carbon monoxide, carbon dioxide, hydrogen, sulfur dioxide, nitrous oxide), excess air coefficient and the dust content of particle matter—PM10, PM2.5. The heating value was also determined for hemp pellets and pine sawdust pellets, accordingly 17.34 and 19.87 MJ·kg−1. The obtained test results were related both to the volume of exhaust gases leaving the boiler and to one kilowatt hour of heat produced. The obtained test results showed that the boiler fed with pine pellets achieved the highest thermal power (P100)—14.17 kW, while the smallest—hemp pellets (C100)—4.92 kW. The CO2 emissivity increased with the addition of pine pellets, from 26.13 g (C100) to 112.36 g (P100) relating to 1 m3 and from 430.04 g (C100) to 616.46 g (C25/P75) relating to 1 kWh of heat. In terms of dust emissions, it was found that the combustion of hemp pellets and mixtures thereof is a little worse than that of pine pellets.


1) A concise statement of problem areas; personnel outside of the planning section should be asked to supplement and/or modify a list of these areas. 2) A brief statement as to the proper remedial action that must be taken to correct existing problem areas. Again, the considered opinion of line and staff executives should be requested during the formulation of the short-range action plan. 3) New problem areas currently not processed mechanically or electronically; these should be defined and should be investigated in terms of possible application and solution by use of different source information or processing techniques. 4) A firm schedule against which periodic progress reports may be measured. 5) Using the aforementioned four steps, a general statement recording 1-, 3-, and S-year goals of information handling should be spelled out. This should include a statement specifying the planning philosophy and the general direction in which the plan is approaching the stated objectives.


Accountability has become a major issue in organisations, as it has been identified as one of the main values and key determinant factor of the organisation's effectiveness. Within the organisation, accountability is a value that theoretically underpins behaviours of managers, as they should be held accountable for the decisions made and actions taken. This paper explores empowerment as a motivational tool in exercising accountability, as well as how empowerment shapes one's values and leadership. This paper elicited perceptions of middle managers in an institution of higher learning in Malaysia by using multiple types of data,
such as, interview, questionnaire and virtual social discussion on Facebook. It was found that empowerment enhances managers' skills and
motivation in instituting reward in organisation. Moreover, managers are able to apply the appropriate values required to make decision and take action in pursuit of organisational effectiveness


In this paper, we present an adaptive superpixel-based graph construction method for unsupervised image segmentation. The empirical findings in this study provide a new understanding of applying non-local image patches to image segmentation. We demonstrate that high-level segmentation cues can be revealed by non-local similar patches, and based on it the similarity between superpixels overlapped with these similar patches can be adaptively constructed. The experimental result on the Berkeley Segmentation Database demonstrates the effectiveness and superiority of the proposed algorithm.


FIELD: organic chemistry. SUBSTANCE: product: benzoxazinones of the formula (I) where X is halide; Xis trihalidemethyl or pentahalideethyl and Z is O that can be used for inhibition of reverse transcriptase activity of HIV (including resistant species) and for prevention and treatment of HIV-infections and AIDS. Indicated compounds can be used also as their pharmaceutically acceptable salts, or as components of pharmaceutical compositions using both separately and in combination with other antiviral agents, immunomodulating agents, antibiotics or vaccines. Invention relates to also methods of treatment of AIDS and methods of prevention or treatment of HIV-infections. EFFECT: improved method of synthesis, enhanced effectiveness of prophylaxis and treatment.


Tel.: +2348036904117 Introduction: Diabetes mellitus is a chronic metabolic disorder which has the potential of leading to the development of microvascular complications such as retinopathy, nephropathy and neuropathy. Peripheral sensory neuropathy is common among persons with type 2 diabetes, and manifests as loss of sensory modalities such as touch, joint position and vibration sense. The vibrometer is an electronic device used in clinical diagnosis of peripheral neuropathy as well as in quantifying the extent or severity of the condition. Aim: to determine the prevalence of peripheral neuropathy among individuals with type 2 diabetes, as well as outline its associated predisposing factors. Methodology: One hundred (100) adults with type 2 diabetes participated in the study. Relevant history such as age, sex, and duration of diagnosis of diabetes was obtained from each participant. Anthropometric indices – height, weight and waist circumference—were also measured. A vibrometer was used to assess vibration perception threshold (VPT) in both feet of each participant. A VPT of greater than 15 volts in one or both feet was used as diagnosis of peripheral neuropathy. Serum lipids (triglycerides and cholesterol) were also assayed. Results: Females comprised 68% of the study population. Mean age of study participants was 57.8±11.6 years and mean duration of diagnosis of diabetes was 10.1±6.6 years. Prevalence rate of peripheral neuropathy in study population was 75%. The independent predictors of peripheral neuropathy were age (OR = 4.00; 95% CI 1.46 – 10.77) and duration of diagnosis of diabetes ≥ 10 years (OR = 3.37 95% CI 1.23 – 9.25). Conclusion: the risk of developing diabetic peripheral neuropathy increases with age and with the length of time an individual has been known to have diabetes mellitus. This information will be helpful in identifying high risk groups during screening programmes for diabetic peripheral neuropathy.


Multilayer synthetic quasi-TEM transmission lines (TLs) are applied to the CMOS hybrids miniaturization. Two meandered synthetic quasi-TEM TLs are integrated in the form of CMOS multilayer structure and shielded by the mesh ground plane. Theoretical analyses are performed to extract the guiding properties of the multilayer synthetic quasi-TEM TLs. The extracted results are applied to the CMOS hybrid designs. The prototypes of Ka-band power divider and 180-degree hybrid (rat-race hybrid) are implemented by using the standard 0.18-mum 1P6M CMOS technology, achieving the circuit sizes of 180.0 mum times 180.0 mum and 210.0 mum times 480.0 mum, respectively. The experiments show intrinsic loss of power divider is less than 5.26 dB over a bandwidth of 10-GHz when the input return loss is kept higher than 10.0 dB. In the rat-race design, the measured insertion loss is 4.98 dB and the isolation is higher than 17.0 dB.


Objective To determine the content of total saponins in extracts of Clinopodium herb,and investigate the extraction method.Methods The content of total saponins in Clinopodium herb was determined by using spectrophotometry.Results The content of saponin A in Clinopodium herb showed a linear relation with the spectrophotometric absorbance within the range of 134.6-673.0 μg,and the linear equation was A=0.537 6 c-0.013 6(r=0.998 8).The average recovery of total saponins was 100.2%,and RSD was 1.3%.Conclusion Spectrophotometry is reliable,accurate and suitable for the quality control of the total saponins in extracts of Clinopodium Herb.


ABSTRACT This study explores how five pre-service subject teachers from different disciplines made sense of and characterized their teacher identity after completing their yearlong pedagogical studies. Leaning on the Bakhtinian dialogical approach and socio-culturally oriented discourse analysis, we examine how the students negotiated multiple voices in their narratives (interviews) and how they positioned themselves in relation to these voices. In the students' identity negotiation, the Discourse based on participatory pedagogy and education responsibility contradicted with the Discourse of traditional pedagogy that the students had as a cultural resource from their own youth. These different Discourses collided with each other and were tested and reflected in an internal dialogue. Through this process, the students negotiated their prospective subject teacher identity.


Operation of multi-reservoir systems is known as complicated and often large-scale optimization problems. The problems, because of broad search space, nonlinear relationships, correlation of several variables, as well as problem uncertainty, are difficult requiring powerful algorithms with specific capabilities to be solved. In the present study a Self-adaptive version of Melody Search algorithm is presented and applied to obtain Operating Rule Curves for multi-reservoir systems. The self-adaptive mechanism is implemented to satisfy problems constraints and perform algorithm parameters evolution going through different iterations. The research initially evaluates capability of extended algorithm using eight benchmark problems comparing other well-known metaheuristic algorithms, and verifies its effectiveness. Then, the algorithm is adopted for optimal operation of a four-reservoir system located in Karkheh river basin to properly meet agricultural requirements and to decrease the probability of major failures; and finally, the results are provided.


The study deals with the conscious use of the medium "language" in the design of vocational teaching/learning processes in order to make the examination and assessment process of learning outcomes more transparent and appropriate. For this purpose, the study focuses on the use of tasks in written examinations in vocational teaching and in particular on the operators used in these. The question will be investigated as to whether the teaching of operator meanings and the actions required with them leads to an improvement in the results of processing and the understanding of tasks among learners. The theoretical approach is based on the knowledge and action theory of AEBLI (1980; 1981), on the basis of which an instrument is developed for verifying the understanding of tasks. To answer the question, a quasi-experimental intervention study in pretest posttest design with one experimental and control group (n=42) is carried out. For this purpose, the instrument is used to verify the understanding of the tasks in the vocation "educator" at a vocational school. For the development of the treatment, selected operators are conceptually defined, which are frequently used in written final examinations of this profession. The experimental results show that instruction on operators has a significant positive effect on the results of the tasks performed by the learners in the experimental group. This is also obvious for an improved understanding of the learner's tasks, since here too there are significant positive changes in individual segments of understanding. Finally, conclusions are derived for the development of a mutual understanding of the tasks of teachers and learners as well as for the pedagogical-practical activity of vocational teaching. Keywords: operator, academic-pedagogical special language, speech comprehension, didactic order


We consider the effective field theory formulation of torsional gravity in a cosmological framework to alter the background evolution. Then we use the latest H 0 measurement from the SH0ES Team, as well as observational Hubble data from cosmic chronometer and radial baryon acoustic oscillations, and we reconstruct the f(T) form in a model-independent way by applying Gaussian processes. Since the special square-root term does not affect the evolution at the background level, we finally summarize a family of functions that can produce the background evolution required by the data. Lastly, performing a fitting using polynomial functions and implementing the Bayesian information criterion, we find an analytic expression that may describe the cosmological evolution in great agreement with observations.


3089 Deep venous thrombosis (DVT) in the critically ill patient is not a new problem and represents an old foe to those who regularly care for trauma patients (1). Until the introduction of highresolution ultrasound equipment in the mid 1980s, lower extremity (LE) DVT was diagnosed through venography, a painful and time-consuming procedure that caused DVT development in a small percentage of patients (2). Ultrasound delivered through traditional consultative pathways or at the point-of-care (POC) is now considered the effective gold standard (3). Few patients apart from those with cancer are as susceptible to the development of DVT as major, polytrauma victims (4). These patients are also at increased risk because of the coexisting illness and the potential for ongoing hemorrhage, which may limit the use of anticoagulation as well as localized thrombolysis (5). In the study published in this issue of Critical Care Medicine by Thorson et al (6), researchers determined that the prevalence of LE DVT development among high-risk trauma patients is high and the proportion of asymptomatic DVTs is alarming. A risk stratification tool to identify high-risk patients for LE DVT proved successful when compared against controls. This study also raises several dilemmas. First, the fact that LE DVT development is common in high-risk trauma patients, even with prophylaxis. The potential for Medicare, and then, third party insurers, to drastically limit hospital reimbursement for trauma patients who develop LE DVT is a sobering thought. DVTs are so frequent that additional large numbers of patients could effectively receive free care and seriously strain trauma facilities. For the study, the facility performed approximately 291 ultrasound examinations on 106 study patients and generated charges of $308,751. This number represented 0.5% of total hospital charges for these patients. The researchers even ponder if "looking" for DVTs will increase the baseline prevalence of DVT, referring to surveillance bias phenomenon. This poses an interesting philosophical dilemma; is it better not to even look for DVT? Obviously, performing an LE ultrasound examination will not itself cause DVT development. We are discussing asymptomatic and silent DVTs that eventually resolve without obvious embolization during the patients' hospital stay. The difficulty is that such asymptomatic DVTs regularly kill people by becoming massive pulmonary embolisms unsuspected by patients, physicians, and families (7, 8). Is the cost of missing some asymptomatic DVTs and not being reimbursed for the few that result in a recognized PE less than disclosing to Medicare how many patients on a trauma service have DVT? In dollars, it may well be. What is clear is that for some, if not many trauma services, screening for LE DVTs is part of a future where compensation may depend on early detection. The ultrasound examination is quite accurate, potentially easily repeatable, and can be relatively inexpensive (9). This last fact seems less convincing if the $1,061.00 per examination charged by the author's institution is relevant. There is also the cost of extra demands on traditional consultative imaging pathways, which are already burdened by service to the entire hospital. The authors do an excellent job mentioning critical care or POC ultrasound performed by the clinician caring for the critically ill patient. Multiple fatal barriers are offered up as to why this is actually not a viable solution to the problem of regular screening for high-risk trauma patients. However, each of these points is highly debatable and worthy of doing so. First, because cost drives so much of what we do today, is the cost to the healthcare system. The authors contend that there would simply be a transfer of money from radiology to critical care. This is not quite accurate for several reasons. Many clinicians fail to or are blocked from billing for critical care ultrasound performance. Assuming an even playing field where critical care physician can obtain reimbursement for their POC ultrasound studies, the charge for a POC LE ultrasound examination to rule out DVT by clinicians is close to one fifth of what the authors institution charged (10). Doubt is raised about the accuracy of the examination in the hands of critical care clinicians; yet, acceptable results have been obtained repeatedly by a variety of clinical specialists (9, 11, 12). The POC ultrasound examination has proven to be just as accurate as the traditional radiology approach in the largest comparison study published to date (13). The issue of time, given that many trauma facilities are already stretched to the limit between patient care and teaching, is an important one. Fortunately, the focused LE ultrasound examination takes <3.5 mins to perform (12). This would allow medical students, residents, or fellows to perform screening examinations during rounds and then duplicate them in teaching rounds at a later point. The last issue is one of the available manpower. This is challenging, but critical care is hardly the first specialty faced with a new development that requires training physicians who are already in practice as well as fellows. Considerable efforts are under way to train critical care fellows and their teachers. Society of Critical Care Medicine now runs two annual courses to meet demand, and an increasing number of fellowships are teaching ultrasound. A long-term solution to the manpower issue is the increasing number of medical *See also p. 2967.


In a recent paper the present authors proposed a way to find a new class of analytical solutions for gravity resonances. In this letter we give a step further to show a generalization of this method of finding analytical solutions for fermion localization in Randall-Sundrum (RS) models. This is important for understanding the structure of resonances of massive modes. As before, it is defined a smooth version of the warp factor with an associated function. We find the associated equation and the boundary conditions satisfied by it for the fermion case. After this we find the new solutions to this equation and analyze the spectrum of resonances. We also show that there exist coupling with scalar and fermions that gives discrete massive localizable modes.


Canada is a leading global agricultural exporter, and roughly half of Canada's farmland is in Saskatchewan. New agrivoltaics research shows increased biomass for a wide range of crops. This study looks at the potential increase in crop yield and livestock in Saskatchewan through agrivoltaics along with its financial implications. Then, the legislation that could influence the adoption of agrivoltaics in Saskatchewan is reviewed. Specifically, experimental results from agrivoltaic wheat production are analyzed for different adoption scenarios. The impact of converting the province's pasture grass areas to agrivoltaics and using sheep to harvest them is also examined. The results indicate that approximately 0.4 million tons of wheat, 2.9 to 3.5 million tons of forage and 3.9 to 4.6 million additional sheep can be grazed using agrivoltaics in Saskatchewan. Only these two agrivoltaics applications, i.e., wheat farmland and pastureland, result in potential additional billions of dollars in annual provincial agricultural revenue. The Municipalities Act and the Planning and Development Act were found to have the most impact on agrivoltaics in the province as official community plans and zoning bylaws can impede diffusion. Agrivoltaics can be integrated into legislation to avoid delays in the adoption of the technology so that the province reaps all of the benefits.


A new japonica rice variety Nanjing 50 with good eating quality, high yield and multi-resistance was developed from Japanese variety Kantou 194 carrying low-amylose content gene Wx-mq and resistance gene Stv-bias the male parent to cross with Chinese variety Wujing 13 in Jiangsu province, through the method of mixed pedigree combining with the technology of marker assisted selection. This variety had many high yield characteristics, such as proper height, vigorous growth, strong tillering ability and large spike. Its yield structure for 650 kg/667 m2 should meet these indicators that the number of effective panicles per hectare, grain number per panicle, seed setting rate and 1 000-grain weight were 200,000, 140~150, 90%~95% and 25 g respectively. Nanjing 50 had not only good resistance to most of disease including rice blast, stripe virus, sheath blight and bacterial blight, but also had excellent eating quality with low amylose content compared with that of ordinary rice varieties, and it was suitable for commercial development for high-grade quality rice. The variety was released to farmers by Jiangsu Provincial Crop Variety Release Committee in 2013 and could be cultivated in south of Jiangsu Province.


OF THE DISSERTATION ii ACKNOWLEDGEMENTS iv DEDICATION vi TABLE OF CONTENTS vii LIST OF FIGURES xi LIST OF TABLES xxii Chapter


THE STRUCTURAL BASIS OF EQUINE NECK PAIN By Nicole Rombach To date there are large gaps in the knowledge about the phenomenon of neck pain in the horse. This dissertation, which consists of four studies, aims to elucidate neck pain in the horse based on the concepts of neuromotor control and dynamic stability associated with neck pain in people. The first study describes the anatomy and morphology of two perivertebral muscles, namely, m. multifidus cervicis and m. longus colli. Both muscles are closely associated with neuromotor control and dynamic stability in people with neck pain. Based on findings in dissection, their anatomy and morphology are similar to those in people. As such, both muscles may play a role in vertebral stability in the neck of the horse. The second study investigated the prevalence and severity of osseous degenerative lesions in the articular process articulations of the equine cervical and cranial thoracic spine. Based on grading of osseous lesions of the articular process articulationsin this anatomical region, osseous degeneration is most prevalent in the mid-cervical and cervicothoracic region, and more prevalent in older and larger horses. In the first part of the third study, a technique was developed for repeatability of measurement of the cross-sectional area of m. multifidus cervicis and m. longus colli in the equine cervical spine, using ultrasound imaging. In the second part of this study, intraand inter-operator repeatability was determined for measurement of the cross-sectional area of m. multifidus cervicis and m. longus colli in the equine cervical spine, using the ultrasound imaging technique that was developed in the first part of the study. Evaluation of the size of both muscles is of particular interest in programs of therapeutic rehabilitation, which aim to increase the size of perivertebral muscles to improve vertebral stability and reduce the recurrence of episodes of neck pain, particularly those associated with osseous degenerative changes in the cervical spine. Results from this study show that US is a repeatable technique for CSA measurement of m. multifidus cervicis and m. longus colli at specific levels of the equine cervical spine. The fourth study used behavioral responses from horses during a manual examination to develop an ethogram of specific behaviors that may be observed in manual examination of horses with neck pain. Distinct aversive behavioral responses from manual palpatory assessment and mobilization techniques in the cervical spine and cervicothoracic junction of horses were identified in some horses with neck pain. This study also investigated whether manual examination techniques could be applied in the equine cervical spine to identify horses with diagnosed neck pain as compared to control cases. In blinded examination, the manual therapy practitioner who carried out the evaluations was able to correctly place each horse into its respective category of neck pain versus control subject, according to responses from the manual examination techniques that were applied to the


Networks can be used to represent a variety of real world complex interacting systems in which vertices represents interacting entities and a network link represents a connection between two nodes or entities. A citation network is a network that gives the information about the citations within a collection of documents. Citation networks are widely utilized in a variety of graph mining situations like citation recommendation and locating research hotspots. Link prediction is considered as a significant task in data and graph mining and deals with prediction of the future or missing network links based on the given network knowledge. There are many link prediction techniques which can be mainly classified into supervised and unsupervised techniques. The purpose of this work is to discuss and analyze the current state of link prediction in citation networks.


This paper aims to solve the optimization problems in far-field wireless power transfer systems using machine learning techniques. We assembled the RF power transfer robot, which can emit the electromagnetic wave to charge the energy harvesters that are deployed in the experimental field. The wireless transmitter intends to charge all the energy harvesters in a fair manner. Since the energy harvesters can be either stationary or mobile, a multi-armed bandit(MAB) problem is formulated and we use Upper Confidence Bound(UCB) algorithm to determine the optimal transmission strategy. As the number of the transmitters is increased, multiple wireless transmitters coordinate with each other to boost the levels of energy harvesting at all energy harvesters. Correspondingly, we formulate a combinational MAB problem and UCB algorithm is applied to determine the optimal transmission strategy for each transmitter. The simulation results prove the superiority of the Multi-armed bandit approach in solving the proposed optimization problems.


We aim to apply cognitive neuroscience insights to vocabulary learning practice. Towards this end, we review current educational methods in relation to important characteristics of the mental lexicon, such as similarity-coding. This shows that methods relate poorly to the mental lexicon, and that especially contrasting - explicitly distinguishing similarities - receives little attention. To remedy this, we run experiments to put these findings into practice. First, we ask participants to learn artificial vocabulary using retrieval practice multiple-choice, manipulating the orthographic and semantic similarity of distractors. The prediction is that learning will be harder but more effective depending on similarity and translation direction. Second, we test whether participants show indications of gradient descent learning when guessing in recall retrieval practice. Thirdly, we use cognitive neuroscience and large scale word learning data to model the mental lexicon. Combined, these studies potentially offer relevant scientific and societal insights, applicable to school settings.


The defects connected with the presence of phosphor in both optical and EPR spectra are examined. In the visible spectral range the color centres connected with the PO4-2 defects (POHC) were investigated. The spatial distributions of the respective bands found both for optical and EPR ranges were attributed to the lower valency phosphor defects. The thermally generated changes in both the types of spectra were recorded. The examinations of yellow luminescence (in the 500-750 nm range) connected with Ge06 and conditioned by the phosphor presence have been initiated.


On the occasion of the eight hundredth anniversary of the Battle of Bouvines (July 27, 1214), this essay examines its significance for the Capetian monarchy and its impact inside and outside the French kingdom. It argues that Philip II Augustus's victory safeguarded the administrative reforms he had undertaken since 1190, boosted royal ideology, extended royal control in northwestern and central parts of France at the expense of Anglo-Angevin claims, cleared the path for the Albigensian crusade in the south, and eliminated Flemish and German threats from the north and east; the battle's ramifications for internal English, Flemish, and German affairs were far-reaching. The battle thus secured Capetian supremacy in France throughout the thirteenth century, but at the turn of the fourteenth century Flanders and Gascony again posed intractable problems.


verges 4 times faster than backpropagation, and about 1.5 times faster than Quickprop, although both backprop-agation and Quickprop needed non-standard extension to converge at all. The fact, that the pure RPROP algorithm was used and no further modiications had to be applied, again demonstrates the advantage of the new algorithm with respect to the simplicity of use. In the following, the best results of the several learning algorithms are listed in an overview. The gures show the average number of epochs used on the learning tasks described above plus the results on an additional gure recognition task. The second row from below shows the results of the RPROP-algorithm using the standard parameter choice (4 0 = 0:1; 4 max = 50:0). As can be seen, even without annoying parameter tuning very good results can be achieved. The proposed new learning algorithm RPROP is an easy to implement and easy to compute local learning scheme, which modiies the update-values for each weight according to the behaviour of the sequence of signs of the partial derivatives in each dimension of the weight-space. The number of learning steps is signiicantly reduced in comparison to the original gradient-descent procedure as well as to other adaptive procedures, whereas the expense of computation of the RPROP adaptation process is held considerably small. Another important feature, especially relevant in practical application, is the robustness of the new algorithm against the choice of its initial parameter. RPROP is currently beeing tested on further learning tasks, for example on pattern sets containing continuous target values. The results obtained so far are very promising and connrm the quality of the new algorithm with respect to both convergence time and robustness.


Talk helps organize the activities it is part of; people maintain regularity of activity through the typification of talk. Similarly, the recognizable similarity among written texts (i.e., recognition of genre) helps maintain social and cognitive structure within activities producing or using those genres. Enduring written texts and systems of texts provide a conservative, reproductive force on local activities. Events are particularly held accountable with those texts that count as knowledge, and thus knowledge-bearing texts are influential in the organization of daily life. Further, disciplines concerned with the production of knowledge represented in textual form develop their structures of social and intellectual practice in dialectic with the textual forms by which knowledge is created and circulated. An examination of the discursive organization of the fields of knowledge production gives us tools for examining the roles knowledge serves within modern culture and opens up questions of how society is...


The classic old definition of congenital heart block by Yater (1929) is still generally accepted: 'Heart block establishedin a young patient. There must be some evidenceof the existenceof the slow pulse at a fairly early age and absence of a history of any infection which might cause the condition after birth: notably diphtheria, rheumatic fever, chorea and congenital syphilis'. However, other definitions are used. We systematicallyreviewed 1825 cases from 38 separatestudies. We conclude that complete AV blocks detected in utero in the absence of structural abnormalities differ from blocks detected later in life with respect to pathogenesis (they are generally associated with maternal anti-Ro/SSA antibodies), poorer childhood prognosis, increased risk of developing late-onset dilated cardiomyopathy, different maternal clinical features and increased risk of recurrence in future pregnancies.For these reasons we propose a new modern definition of congenitalcomplete AV block which might be acceptable to cardiologists, rheumatologists, pediatricians and obstetricians: 'an AV block is defined as congenital if it is diagnosed in utero, at birth or within the neonatal period (0-27 days after birth)'.


This paper presents a low power head-mountable deep brain stimulation (DBS) device operated with harvested energy. The electrical energy generated by a mini solar panel is used to operate the low power head-mountable DBS device. The DBS device consists of a power management unit, a low-power microcontroller, and a constant current source. The proposed indoor solar energy harvesting system can supply a sufficient amount of dc power to run DBS device or to charge battery for DBS device. The energy harvesting scheme might increase the longevity of the low power DBS device. The size of low power DBS device is 25 mm (L) × 25 mm (W) × 5 mm (H). This device can deliver continuous stimulation electric pulses with variable parameters of width (80–200) µs, frequency (100–250) Hz, and amplitude (0.25-10) mA. The frequency and amplitude of the current pulse are controlled by potentiometer according to the requirement for the activation of abnormal neural tissues.


A combined experimental and computational study of the dinuclear rhenium(V) complex containing (ReO)2(µ-O) core is presented in this article. The solid-state [Re2Cl4(O)2(µ-O)(3,5-lut)4] (3,5-lut = 3,5-dimethylpyridine) complex was characterised structurally (by single crystal X-ray diffraction) and spectroscopically (by IR, NMR, UV-VIS). The electronic structure was examined using the density functional theory (DFT) method. The spin-allowed electronic transitions were calculated using the time-dependent DFT method, and the UV-VIS spectrum was discussed.


The author develops the concept of the different aspects of TICS Architecture, and shows needs and developments within Europe. Architecture is defined, and concepts are discussed. A glossary of standard terminologies for reference models, architectures and taxonomy is given.<<ETX>>


ADAR1 (adenosine deaminase acting on double‐stranded RNA 1) is an RNA‐editing enzyme that me‐diates adenosine‐to‐inosine RNA editing events, an important post‐transcriptional modification mechanism that can alter the coding properties of mRNA or regulate microRNA biogenesis. ADAR1 also regulates the innate immune response. Here, we have demonstrated that ADAR1 expression increased in LPS‐stimulated macrophages. Silencing ADAR1 by using small interfering RNA in macrophages resulted in the pronounced polarization of macrophages to M1, whereas ADAR1 overexpression promoted M2 polarization, which indicated that ADAR1 can inhibit macrophage hyperpolarization and prevent immune hyperactivity. The RNA‐RNP immunoprecipitation binding assay demonstrated a direct interaction between ADAR1 and miR‐21 precursor. Significant up‐regulation in IL‐10 and down‐regulation in miR‐21 were observed in ADAR1‐overexpressing macrophages. We evaluated miR‐21 target mRNAs and macrophage polarization signaling pathways and found that forkhead box protein O1 (Foxo1) was up‐regulated in cells that overexpressed ADAR1. In a mouse allogeneic skin transplantation model, grafts in the ADAR1‐overexpressed group survived longer and suffered less immune cell infiltration. In ADAR1‐overexpressed recipients, splenic macrophages were significantly polarized to M2, and levels of sera IL‐10 were markedly higher than those in the control group. In summary, ADAR1 modulates macrophage M2 polarization via the ADAR1‐miR‐21‐Foxo1‐IL‐10 axis, thereby suppressing allogeneic graft rejection.—Li, J., Xie, J., Liu, S., Li, X., Zhang, D., Wang, X., Jiang, J., Hu, W., Zhang, Y., Jin, B., Zhuang, R., Yin, W. ADAR1 attenuates allogeneic graft rejection by suppressing miR‐21 biogenesis in macrophages and promoting M2 polarization. FASEB J. 32, 5162–5173 (2018). www.fasebj.org


Visual quality measures seek to algorithmically imitate human judgments of patterns such as class separability, correlation, or outliers. In this paper, we propose a novel data‐driven framework for evaluating such measures. The basic idea is to take a large set of visually encoded data, such as scatterplots, with reliable human "ground truth" judgements, and to use this human‐labeled data to learn how well a measure would predict human judgements on previously unseen data. Measures can then be evaluated based on predictive performance—an approach that is crucial for generalizing across datasets but has gained little attention so far. To illustrate our framework, we use it to evaluate 15 state‐of‐the‐art class separation measures, using human ground truth data from 828 class separation judgments on color‐coded 2D scatterplots.


As well known, low rank representation method (LRR) has obtained promising performance for subspace clustering, and many LRR variants have been developed, which mainly solve the three problems existing in LRR: 1) Problem of mean calculation; 2) Problem of deviating from the real low rank solution; 3) Problem of high computation cost on the large-scale data. In this paper, we first propose a universal LRR method referring to the first two problems. More specifically, we introduce the ability of removing the optimal mean automatically into LRR and extend it to a Schatten $p$ -norm minimization problem. Then, referring to the third problem, we reformulate the universal LRR version as an equivalent fast optimization version by removing the null space of data. More importantly, the effective theory proof is proposed to guarantee that the fast optimization method can dramatically improve the algorithmic computation efficiency on the large-scale data but without any loss of information. Finally, experimental results demonstrate the effectiveness and efficiency of the proposed method.


1. Change agent: d e s c r i p t i o n o f the i n d i v i d u a l s and orga n i z a t i o n conducting the prevention program 1.1 d e s c r i p t i o n 1.11 p u b l i c or p r i v a t e agency 1.12 size of the o r g a n i z a t i o n 1.13 l o c a t i o n 1.14 t r a i n i n g had or r e q u i r e d o f personnel 1.15 o r g a n i z a t i o n a l a f f i l i a t i o n s , e.g., p a r t o f Boy Scouts 1.16 d e s c r i p t i o n of person i n d i r e c t contact w i t h t a r g e t p o p u l a t i o n 1.17 dates of ope r a t i o n ' 3a source of items used to describe the t a r g e t population and delinquency s t a t u s was Moles, 0 . J r . , L i p p i t t , R, 6i Withey, S. B. Se l e c t i v e review o f research and t h e o r i e s concerning the dynamics • o f delinquency, Inter-Center Program o f Research on Ch i l d r e n , Youth and Family L i f e , Ann Arbor, Mich. 1959; the an a l y s i s o f change agent and program draws on L i p p i t t , R., Watson, J . , 6c Westley, B. The dynamics o f planned change, Harcourt, Brace & Co. N.Y, 1958.


This paper summarizes the intermediate lessons learned from the analyses of the risk management problems in three technological endeavors. These problems are: the absence of a structure for rewarding successful project risk management; the need for an ever-more accurate economic measure of risk; and the difficulty of transferring risks to contract-bound independent outsourcing entity. This paper also describes recent advancement towards providing answers to these challenges and future research endeavors in this field.


Jamie O'Neill (b. 1962) has written three novels: Disturbance (1989), Kilbrack (1990), and the award-winning At Swim, Two Boys (2001). Disturbance and Kil brack are relatively short and focus mainly upon a single character in a small community; At Swim, Two Boys, in contrast, is a long, sweeping, deeply histor ical novel, whose technique and style might best be described as modernist in the vein of Joyce's Portrait The rendering of voice and consciousness is complex and tigh?y connected to the novel's major theme of coming-of-age within and against the tide of historical crisis. 'O'Neill has come to be regarded as one of the most gifted of contemporary Irish novelists; the novelist's sheer delight and vir tuosity in language shows in such passages as this:


PURPOSE: To detect an open load having a low threshold with high accuracy by means of a simple circuit configuration by incorporating a device which only turns on a transistor having a high resistance value and a device which detects the open-load when a current falls within a low-value range in the configuration. CONSTITUTION: When an open-load detecting circuit is switched on and a synthesized transistor TR is turned on, a control signal OFFG rises to '0' so that the signal OFFG may be triggered by a TRTP2 only and a TRTP1 which is held in a cut-off state by a signal OFFPP operates. Then the TRTP2 is controlled and a load current IL is generated, and then, the gate voltage VG2 of the TRTP2 increases. Since the TRTP1 is cut off during the operation, the gate voltage VG1 of the TRTP1 rises and the current flowing through a load only flows through the auxiliary TRTP2. An alarm signal AL 1 rises to '0', because the whole load current flows through the TRTP2. When the current flowing to the load decreases and becomes a threshold IL 0 , an open-load is detected, because a signal OL is turned on. COPYRIGHT: (C)1994,JPO


The genetic instability of cancer cells may be related to inappropriately activated DNA repair pathways. In present study, the modulated expression of DNA-dependent protein kinase (DNA-PK), a major DNA repair protein, in human cancer metastatic cells was tested. The expressions of Ku70/80, regulatory subunit of DNA-PK, and the Ku DNA-binding activity in various highly metastatic cell lines were higher than those in each parental cell line. Also, the expression of DNA-PKcs, catalytic subunit of DNA-PK, and the kinase activity of the whole DNA-PK complex in highly metastatic cells were significantly increased as compared to those of parental cells, suggesting that the enhanced DNA repair capacity of metastatic cells could be associated with aberrant use of DNA repair, which may mediate tumor progression and metastatic potential. Increased EGFR (epidermal growth factor receptor) signaling has been associated with tumor invasion and metastasis, and the linkage between EGFR-mediated signaling and DNA-PK has been suggested. This study showed that PKI166, the new EGFR tyrosine kinase inhibitor, modulated the expressions of Ku70/80 and DNA-PKcs and also revealed the chemosensitization effect of PKI166 against metastatic cells may be in part due to inhibition of Ku70/80. These results suggest that interference in EGFR signaling by EGFR inhibitor resulted in the impairment of DNA repair activity, and thus DNA-PK could be possible molecular targets for therapy against metastatic cancer cells.


In this paper, we find a conformal vector field as well as a Killing vector field on a compact real submanifold of the canonical complex space form (Cm, J, 〈 , 〉). In particular, using immersion ψ : M → Cm of a compact real submanifold M and the complex structure J of the canonical complex space form (Cm, J, 〈 , 〉), we find conditions under which the tangential component of Jψ is a conformal vector field as well as conditions under which it is a Killing vector field. Finally, we obtain a characterization of n-spheres in the canonical complex space form (Cm, J, 〈 , 〉).


New etching solution for chemical penetrant inspection of Inconel(R) 718 castings and weldments. Etchant does not introduce artifacts mistaken for defects. Applied by swabbing or by immersion. Used to detect unwanted residues of Nioro(R) (or equivalent) gold brazing alloy on type 347 stainless steel.


A miniaturized dual-band half-mode patch antenna for water utility Advanced Metering Infrastructure (AMI) is proposed. The proposed antenna consists of a semicircular patch with a shorting via to generate the higher order mode. In order to reduce the size in half, the proposed antenna adopts a half-mode concept. The radius of the proposed antenna is 209 mm and the height is 30 mm. The simulated 10-dB return loss bandwidths are 3 MHz (264 MHz - 267 MHz) at the low band and 10 MHz (907 MHz - 917 MHz) at the high band. The simulated results show that the proposed antenna has an omni-directional radiation pattern with a maximum gain of 2.4 dBi at the low band and a directional radiation pattern with a maximum gain of 7.7 dBi at the high band.


Analysis of intra-atrial electrograms (EGMs) nowadays constitutes the most common way to gain new insights about the mechanisms triggering and maintaining atrial fibrillation (AF). However, these recordings are highly contaminated by powerline interference (PLI) due to the large amount of electrical devices operating simultaneously in the electrophysiology laboratory. To remove this perturbation, conventional notch filtering has been widely used. However, this method adds artificial fractionation to the EGMs, thus concealing their accurate interpretation. Hence, the development of novel algorithms for PLI suppression in EGMs is still an unresolved challenge. Within this context, the present work introduces the joint application of common notch filtering and Wavelet denoising for enhanced PLI removal in AF EGMs. The algorithm was validated on a set of 100 unipolar EGM signals, which were synthesized with different noise levels. Original and denoised EGMs were compared in terms of a signed correlation index (SCI), computed both in time and frequency domains. Compared with the single use of notch filtering, improvements between 4 and 15% were reached with Wavelet denoising in both domains. As a consequence, the proposed algorithm was able to efficiently reduce high levels of PLI and simultaneously preserve the original morphology of AF EGMs.


Objective: To investigate the effect of transforming growth factor-β1(TGF-β1) on store-operated calcium entry(SOCE) and the role of SOCE on TGF-β1-promoted proliferation of airway smooth muscle cells.Methods: Rat airway(bronchial) smooth muscle cells(ASMCs) were cultured and then treated with or without TGF-β1 for 24 h;intracellular Ca2+ concentration was measured with Fluo-3/AM fluorescence by laser confocal microscope;proliferation of ASMCs was determined with MTT reduction assay.Results: In TGF-β1-treated ASMCs,intracellular Ca2+ increased due to the higher Ca2+ releasing than that in control cells,and the Ca2+ increased due to SOCE was also higher than that in control ASMCs.The proliferation of ASMCs induced by 2.5% FBS was higher in TGF-β1-treated ASMCs when compared with control cells;this promoting effect of TGF-β1 on ASMC proliferation was inhibited by non-specific Ca2+ channel blocker SKF-96365(10 μmol/L) and Ni2+(100 μmol/L),but not by La3+(100 μmol/L),which were proven to be effective in inhibiting SOCE of ASMC in our previous study.Conclusion: Our findings demonstrate that TGF-β1 has a regulatory effect on SOCE of rat ASMCs,and this effect may contribute to its promotion on the proliferation of ASMC.Our results may shed some light on the mechanism of airway remodeling during asthma.


By using the Kalman filtering method and projection theory, the existing white noise estimation theory is extended to general stochastic systems, where the system noise is correlated at adjoining times, and the system noise and measurement noise are correlated at same and adjoining times. The unified optimal and steady-state white noise and quasi-white noise estimators are presented. A simulation example shows their effectiveness.


Reading Paulo Freire' s Pedagogy of the oppressed, one might easily conclude that rhetoric has no place in a classroom so thoroughly imbued with the ethics of dialogue. However, this essay suggests that rhetoric plays a productive and in fact necessary role in Freire's pedagogy of the oppressed. Drawing from the sophistical techniques of imitatio and dissoilogoi, I suggest that true liberation from a dominated consciousness goes through rather than around the methods of rhetorical persuasion, methods that not only develop rhetorical skills in students but that also encourage rhetorical performance on the part of the educators. Dialogue remains central to this pedagogy but becomes enriched by its natural counterpart, rhetoric, so that the aim is not only cognitive liberation but the accrual of practical power.


In order to solve the global marine ecological environment problems and ensure their own marine strategic interests, we should participate in the global marine ecological environment governance in an all-round way. There are still some problems in the evaluation system, supervision mechanism, and performance evaluation of the marine ecological environment. Considering the impact and analysis on the ecological environment in the effect of marine governance, this paper puts forward the performance analysis of marine ecological environment governance based on DPSIR (Drive Pressure State Impact Response) and entropy weight TOPSIS model and constructs the performance index evaluation system of marine ecological environment governance combined with the current situation of marine ecological environment governance. Using entropy TOPSIS (technique for order performance by similarity to ideal solution) model and geographic detector, this paper explores the influencing factors of governance performance. From the perspective of marine ecological environment governance effect, the governance effect is good. The influence of pressure factors such as ecological environment, population, and economy is generally large. The main causes of marine environmental pressure are the massive amount of industrial wastewater, the utilization of water resources in coastal areas, and the employees involved in the sea. Through the factor detection method of geographic detector, the strength calculation of the three criteria of pressure-state-response which affect the performance level of marine environmental governance is carried out, and the pressure layer index, state layer index, and response layer index have good response. In marine science and technology innovation ability, government investment in marine construction has a significant impact on environmental governance performance.


Participation in sports activities combined with unique sports resources can provide people with extraordinary experiences. It is especially true for tourism where sports activities are an important content of stay. The aim of this paper is to analyse how sports experiences could be planned and managed for the tourism purposes from the aspect of sports facility managers. In addition, the interrelations within the four realms of an experience were analysed and supported by proposed management models and examples. Results of the analysis indicate that it is possible for a facility to provide a full spectrum of experiences but only if it meets the standards of professional sports. Recommendations suggested by the paper provide new insight on organising the sports offer in the destination, and can be used by sports facility managers in order to better serve sports and sports tourism needs.


Purpose: Chondroid syringoma, previously known as 'mixed tumor of the skin', is a rare benign tumor. It usually presents an asymptomatic solitary firm intradermal or subcutaneous slowly growing nodule. It occurs frequently in the head and neck region of middle-aged men. We would like to report an uncommon chondroid syringoma about the clinical and histologic presentation. about the clinical and histologic presentation.Methods: We experienced two cases of chondroid syringoma on the nose and the upper lip, each other. Both masses were totally excised with clear margin. Results: On histologic examination, the masses showed a biphasic pattern-an epithelial component exhibiting apocrine/eccrine differentiation and a stromal component exhibiting myxoid/collagenous change-consistent with the diagnosis of chondroid syringoma. There have been no evidence of recurrence and malignant transformation during postoperative follow-up. Conclusion: There is no one distinctive clinical feature that is specific for chondroid syringoma. However, it should be included in the differential diagnosis of a solid nodule in head and neck region with long standing duration, such as epidermal inclusion cyst, pilomatrixoma, dermoid cyst, sebaceous cyst, neurofibroma, and basal cell carcinoma.


A review of new results concerning kinetics, thermodynamics and mechanism of epoxy oligomers curing with various nucleophilic agents (amines, phenols, carboxylic acids) has been made. The concept of the mechanism of such reactions is formulated on the basis of this study. Kinetic data obtained are interpreted within the framework of cyclic transition state. The addition of nucleophilic agent to epoxy ring is rather complicated. It results from preliminary formation of homo- and heteroassociates of reaction system components which finally form reactive cyclic heteroassociates. Reaction products are formed as a result of monomolecular rearrangement with synchronous transfer of electrons in the reactive cyclic heteroassociates.


In this paper we compute the small mass expansion for the functional determinant of a scalar Laplacian defined on the bounded, generalized cone. In the framework of zeta function regularization, we obtain an expression for the functional determinant valid in any dimension for both Dirichlet and Robin boundary conditions in terms of the spectral zeta function of the base manifold. Moreover, as a particular case, we specify the base to be a d-dimensional sphere and present explicit results for d = 2, 3, 4, 5.


This collaborative project aimed to apply the processing technology used for MEMS/NEMS to low-dimensional semiconductor quantum structures in order to explore the physics and application of quantum effects in terms of these structures' elastic degrees of freedom. Progress in this research could lead novel devices developed by hybridizing their elastic functionality into optical and electrical ones. We have successfully formed nanoscale conductive cantilevers by applying self-organization growth technique to the fabrication process. We have also succeeded in fabricating novel semiconductor nano-objects by engineering the strain in lattice-mismatched heterostructures. We have observed for the first time that the piezoresistance is strongly enhanced by the quantum effects in semiconductor low-dimensional structures. This phenomenon can be applied for the highly precise displacement/force sensing. An anomalously large drag effect was observed at high filling factors of the Landau levels in separately contacted two-layer electron systems. Magnetization of MnAs thin films grown by molecular beam epitaxy was studied by cantilever-beam magnetometry. We have theoretically clarified the atomistic processes of self-organized growth of semiconductor surface nanostructures. The influence of the surface on the elastic properties is also theoretically discussed.


Introduction Anthropologists recognise that all societies use intoxicants in aspects of their cultural lives (Lewin 1964; Rudgley 1993). Modern analysis of plants that early peoples believed to have intoxicating or healing properties has, in many cases, demonstrated the presence of pharmacologically active chemicals such as alkaloids and flavonoids that account for these effects. In his work on drugs in ancient and primitive societies Emboden (1979), improving on previous work by Lewin (1964), classified intoxicants into the different groups summarised in Figure 37. Clearly, some well-known intoxicants do not fit easily into one category, opium, for example, being both narcotising and hallucinogenic, depending upon the circumstances of its use. Although the use of animal- and mineral-derived drugs is well described in Egyptian medical practice (Nunn 1996), these do not tend to act as intoxicants, and thus, for this study, the subject materials of interest tend to be derived from plants. Little is known about the use of intoxicants in ancient Egypt beyond the widespread consumption of beer, as part of the staple diet, and wine, by the elite. The cultural use of alcohol by the Egyptians is well documented and will not be considered here. This chapter will focus on a small number of intoxicants that may or may not have contributed to Egyptian society as a medicine, recreational drug or in sacred rituals.


Lake Albert and Albert Nile are a major source of fisheries resources sustaining the riparian communities in Uganda and the Democratic Republic of Congo (DRC). Like all shared bodies of Uganda Lake Albert and Albert Nile fisheries are faced with immense exploitation pressure one time described as the tragedy of the commons. In Uganda, the lake is shared by five riparian districts namely: Buliisa, bundibugyo, Hoima, Kibaale and Nebbi. The lake covers a total estimated surface area of 5,270 km2 with approximately 60% within Ugandan waters (Walker, 1972). It is located in the western part of the great rift-valley at an altitude of 618 m above Sea level. The central parts of the lake are characterized by steep escarpments whereas the northern and southern parts lie in a plain of the rift valley. The plains are gently sloping, resulting in shallow swampy inshore waters in many places. The major inflowing rivers are the Semliki and Kafu in the south, and the Victoria Nile at the northern tip. The lake has a diverse fish fauna with a gradient of multi-species fisheries in different parts of the lake.


A stack-ring configuration is proposed for designing a dual-band circularly polarized (CP) antenna. Each ring generates different resonant frequencies. A good CP performance at both resonant frequencies is achieved by adjusting the relative distance between the two rings. The two operating bands are separated with a small frequency ratio of 1.07. Measured results show that radiation patterns with good CP characteristics are obtained at the two resonant frequencies.


Abstract Financial markets are seen as one of the most important markets in economic terms. The activities of investors in the financial markets consist in predicting how best to invest the accumulated capital, using all kinds of analyzes and forecasts. In the literature on the subject, apart from fundamental analysis, technical analysis is distinguished. While the first one is to help you choose a specific asset with profitable potential, technical analysis is designed to help the investor find a specific moment that is most suitable for buying or selling. The aim of the article is to demonstrate the potential benefits associated with modifying the default settings of technical analysis indicators on the example of the EUR/USD currency pair using the MetaTrader4 investment platform. Analizing was carried out on the basis of the most popular currency pair in terms of turnover on the Forex market - EUR/USD. The research used an investment strategy based on Parabolic SAR and Relative Strength Index RSI technical analysis indicators, whose indications were verified both in the context of default settings and after the author's modification. The results of the conducted research indicate significant differences, depending on the adopted parameters of the above-mentioned indicators.


In this paper, we consider the robust output containment problem of linear heterogeneous multi-agent systems under fixed directed networks. A distributed dynamic observer based on the leaders' measurable output was designed to estimate a convex combination of the leaders' states. First, for the case of followers with identical state dimensions, distributed dynamic state and output feedback control laws were designed based on the state-coupled item and the internal model compensator to drive the uncertain followers into the leaders' convex hull within the output regulation framework. Subsequently, we extended theoretical results to the case where followers have nonidentical state dimensions. By establishing virtual errors between the dynamic observer and followers, a new distributed dynamic output feedback control law was constructed using only the states of the compensator to solve the robust output containment problem. Finally, two numerical simulations verified the effectiveness of the designed schemes.


km 2 , which account for 60% of the total area of Qinghai-Xizang Plateau. They have been subdivided into 110 maps of regional geological survey at a scale of 1: 250, 000. Mapping of more than two third of the blank regions was completed by the end of last year. Significant progress has been made as evidenced from a large volume of new and important data obtained from the regional geological survey (Bureau of China Geological Survey, 2004a, 2004b, 2004c). These data are extensive and effective for interpretation and re- evaluation of the geological problems that are related to the formation and evolution of Qinghai-Xizang Plateau. Discoveries and identifications of a series of ophiolitic melange zones, main faults and important regional discontinuities offer new, important information to reconstruct the tectonic framework and evolutional history in Qinghai-Xizang Plateau. The significant findings in Yarlung Zangbo ophiolitic melange zone are T 2-3 , T 3 -J 1 radiolarian assemblages from argillaceous-siliceous rock in Tangga, Pomulong, and T 2-3 radiolarian assemblages from siliceous rock in Zedang. An ophiolitic melange zone called Shiquanhe-Namu Co-Jiali was identified in Gangdise. Identification of Hongliugou-Lapeiquan ophiolitic zone, Apa-Mangya ophiolitic zone (Cambrian- Ordovician) in A'erjin region and Qimayute-Qimantage ophiolitic zone (Cambrian-Ordovician), Yanbishan-Xiangyangshan ophiolitic zone (Ordovician-Carboniferous), Subashi-Muzitage ophiolitic zone (Carboniferous-Permian) in Kunlun mountain region enables reconstruction a clear evolutional history for the northern Qinghai-Xizang Plateau. Furthermore, Recognition of significant regional angular unconformities in Himalayas (Ordovician / metamorphic basement), Gangdise (P 3 / P 2 , and T 3 /P 3 , J 1-2 /P 3 etc.) and Qiangtang (T 3 /J 2 ) clearly show the evidences of orogenesis in different regions of Qinghai-Xizang Plateau (Wang et al. 2004).


Cross sections for 7/sup 2/D and 8/sup 2/D fine-structure mixing in Rb, induced by collisions with various ground-state atoms and N/sub 2/ molecules, have been determined using methods of atomic fluorescence. Rb vapor, pure or mixed with a buffer gas, was irradiated in a glass fluorescence cell with pulses of radiation from a N/sub 2/ laser-pumped dye laser, populating a /sup 2/D fine-structure state by two-photon absorption. The resulting fluorescence included a direct component arising from the optically excited state and a sensitized component due to the collisionally populated fine-structure state. Measurements of relative intensities of the two components in relation to buffer-gas pressure yielded the following cross sections (in units of 10/sup -14/ cm/sup 2/): Q(7/sup 2/D/sub 3/2/..-->..7/sup 2/D/sub 5/2/) = 1 4.1, 15.5, and 10.0; Q(7/sup 2/D/sub 3/2/reverse arrow7/sup 2/D/sub 5/2/) = 9 .0, 10.5, and 6.9, for Kr, Xe, and N/sub 2/, respectively; Q(8/sup 2/D/sub 3/2/..-->..8/sup 2/D/sub 5/2/) = 8 .9, 4.9, 12.4, 24.9, 25.8, 12.1, and 43.1; Q(8/sup 2/D/sub 3/2/reverse arrow8/sup 2/D/sub 5/2/) = 5 .8, 3.2, 9.4, 15.1, 17.6, 8.3, and 28.5, for He, Ne, Ar, Kr, Xe, N/sub 2/, and Rb, respectively. Cross sections for the effective depopulation of the /sup 2/D states weremore » also determined.« less


We thank S. Couillard for his interesting comments related to our publication on the effects of interleukin (IL)-5 deficiency on the transcriptome of residual eosinophils of Il5-deficient mice and mepolizumab-treated patients [1]. We indeed document stronger upregulation of the expression of the SOCS3 gene following stimulation with IL-33 ex vivo that is conserved between eosinophils from mepolizumab-treated patients and from Il5-deficient mice. It is too early to conclude on a potential biological significance of increased SOCS3 gene expression in blood eosinophils of mepolizumab-treated patients stimulated with interleukin-33 ex vivo https://bit.ly/3wuXMit


Abstract This paper focuses on an analysis of an application of active learning in the international relations (IR) classroom. We present an experience of the so-called Challenge Game that allows the professor to explore analytical categories and basic assumptions of realist theory of IR. In addition, describing the operation of the game in its basic modality, several variations are also presented in order to help explore realism, both in its classic and structural version. We show that key concepts found in realist and neorealist theories, such as the elements that influence the behavior of states in the international system, different conceptions of power and interests, aspects of competition, the centrality of the rationality of the state, alliances building, balance of power, the anarchy of the system, and the idea of hegemony can be either introduced or revised in a dynamic fashion in an IR theory class. The game has been thought to provide means to promote active (instead of passive) learning. As a result, the class can become more dynamic, with the consequent increase of the students interest on the issue. Besides, the activity can provide an environment for discussion, boosting students' potential to think about the content.