A new approach to assess popularity relies on analysis of the number of times a web article is viewed. Here, a strategy is described to identify chemicals of widespread interest. The strategy makes use of Wikipedia, a rapidly growing publicly editable web encyclopedia that has become an influential knowledge base. While the total number of chemicals mentioned in Wikipedia is unknown, use of the Wikipedia Chemical Structure Explorer (WCSE) developed by Novartis enables identification of those that are described in an Infobox or Chembox along with a Simplified Molecular-Input Line-Entry system (SMILES) code. Using a Python script, all so-listed chemicals (16,243) in Wikipedia were identified and then sorted on the basis of their pageview rankings. Of the 16,243 chemicals, 846 (5.2%) belonged to controlled substances (United States Drug Enforcement Administration), WHO essential medicines, or the top 300 US drugs. These 846 chemicals received 220 million pageviews, which is 41.4% of the pageviews for all members of the Wikipedia chemical list. The number of chemicals described in the entire corpus of Wikipedia remains a tiny fraction of the <107 known chemicals. Much remains to be done to make the venerable literature and data of chemistry readily accessible. Regardless, identification of popular chemicals in this manner can be used to create selected databases, to tailor educational curricula, or to create targeted informational materials (such as safety brochures); such considerations of public demand are likely to engender corresponding widespread interest.


A grid interconnection device 100 comprises a receiver configured to receive an adjustment instruction and a controller configured to control a backward flow power on the basis of the adjustment instruction. The adjustment instruction includes group information indicating an application group to which the adjustment instruction is applied among a plurality of groups G. Customers 30 (each includes a power supply device) are grouped depending on the distance from a substation.


. In this paper we study speedups of dynamical systems in the topological category. Specifically, we characterize when one minimal homeomorphism on a Cantor space is the speedup of another. We go on to provide a characterization for strong speedups, i.e., when the jump function has at most one point of discontinuity. These results provide topological versions of the measure-theoretic results of Arnoux, Ornstein and Weiss, and are closely related to Giordano, Putnam and Skau's characterization of orbit equivalence for minimal Cantor systems.


Pericarditis is common in juvenile polyarthritis, but tamponade is a very rare complication and usually needs pericardiocentesis, pericardiotomy or pericardiectomy. We report an exceptionally rare recurrent tamponade after an 8 years interval in a patient with juvenile polyarthritis: the first tamponade was treated by pericardiotomy; the second episode of adiastole regressed after high dose steroid therapy.


Objective: Comparision of time,manpower used by the circulating nurses and doctors' satisfactory degree and patients' adverse effects after surgery of the lithotomy position before or after general anaesthesia were studied.Methods: 76 patients who need lithotomy position were divided into experimental group and comparision group.Experimental group patients placed lithotomy position before intubation.The patients cooperated actively.Comparision group patients placed lithotomy position after intubation.Results: The time,manpower,doctors' satisfactory degree and patients' adverse effects after surgery diverse significantly between the two groups (P0.01).Conclusion: The general anesthesia patient can cooperate actively with sober condition,and circulating nurse can work more efficiently and the patients feel more comfortable after surgery.


The type of apparatus designed by Dingle and Pryce for determining the concentration of carbon dioxide in air by non-spectroscopic measurement of its absorption of infrared has been modified so as ...


Graphical user interface interaction interview (GUI-ii), is a recently purposed method in which designers can remotely co-design and review GUI prototypes by eliminating the need for physical prese ...


Filters made of cellulose acetate and nitrate were saturated with toluene or bromobenzene and interposed between aqueous solutions. The membranes thus formed behaved like cation exchange membranes with the same capacity for both solvents. K - Na bi-ionic potential, its dependence on temperature, K - Na selectivity and mobility ratio were similar in membranes saturated with the above solvents. However the absolute magnitude of the diffusibility was some 30 times lower in toluene saturated membranes. Activation energy of membrane conductance was higher by about 3800 cal/mole in the toluene saturated membrane. Electroosmotic phenomena in the membranes were negligible or nil. It is suggested that these membranes represent a prototype of ion exchange membranes, where the fixed charges with their counterions and hydration shell are embedded in hydrophobic medium.


The thermal expansion of CD4 solutions in the orientational glass C60 with molar concentration of deuteromethane 20 and 50% has been investigated in the temperature range 2.5–23 K. The orientation ...


Targeting on some serious foundry defects, similar to micro cracks occur in a band casting, the analysis was carried out from the aspect of thermal stress contribution during solidification by using numerical simulation method. The 3D thermal stress contribution in the casting during solidification was calculated by ANSYS software. Based on its formation mechanism, a hot crack prediction method was presented, and stress status of semi-solid phase zone in band casting was focused. The area that has serious hot crack tendency in the casting can be confirmed using the method mentioned above. The simulated results are in accordance with the practical cases approximately. The causes of the defect were also presented, which provide foundation for technical design optimization.


: Understanding the level of environmental risk using vehicle-mounted camera traffic scenes is useful in advanced driver assistance systems (ADAS) to improve vehicle safety. We propose a fast, memory-efficient computer vision based environmental risk perception method using a weakly supervised convolutional neural network-based classifier. We use traffic scenes from Berkley deep drive dataset to evaluate the proposed method. Experimental results demonstrate that the proposed method correctly classifies required driver attention levels by considering multiple environmental risk factors. Further, we use class activation mapping to demonstrate that the proposed network is capable of identifying the underlying environmental risk factors.


: Blood products for transfusion may undergo structural or chemical changes when mixed with other infusion fluids, potentially causing hemolysis or coagulation. Therefore, it is generally preferable to use a single infusion route. How-ever, it is often difficult to secure multiple infusion routes in clinical settings. Case: A one-year-old infant was admitted to our hospital for infusions of fresh frozen plasma (FFP; 20 ml/h infusion) for the treatment of solid tumor. A string-like structure was observed in the infusion route after administration of FFP. The structure disappeared after the degradation test using plasmin, leading to the conclusion that it was composed of fibrin. Discussion: Reacting FFP with calcium results in fibrin precipitation. Given that Ringer's solution which contains calcium was used as the main infusion in this patient, we hypothesize that the saline washout of Ringer's solution after the prior infusion was insuf-ficient at the time of FFP administration. It is also possible that a slow infusion rate and FFP stagnation in the infusion route contributed to fibrin deposition. Conclusion: This case emphasizes the importance of performing a thorough saline washout of the infusion fluid prior to the transfusion and preventing blood products from mixing with other infusion drugs.


The paper considers the estimation of formation of professional competence of cadets in military high school at various stages of training, and ways to improve the quality of education based on the feedback of the university with the customer.


Objective: We created normative growth charts of amygdala functional connectivity in typically developing youth and assessed age-associated deviations of these trajectories in psychosis spectrum youth, and explored how these disruptions are related to clinical symptomatology. Methods: Resting state functional neuroimaging data from four samples (3 cross-sectional, 1 longitudinal) was collected on 1062 participants (typically developing controls=622, psychosis spectrum=194, other psychopathology=246, ages 10–25 years). We assessed deviations in youth with psychosis spectrum and other psychopathology in age-related changes in resting state fMRI (rsfMRI) amygdala to whole brain connectivity from a normative range derived from control youth. We explored relationship between age-associated deviations in amygdala connectivity and positive symptoms in the patient group. Results: Normative trajectories demonstrated significant age-related decreases in centromedial amygdala connectivity with the rest of the brain. In contrast, psychosis spectrum youth failed to exhibit any significant age-associated changes between the centromedial amygdala and prefrontal cortices, striatum, occipital cortex, and thalamus (all q<.1). Age associated deviations in centromedial amygdala-striatum and centromedial amygdala-occipital connectivity were unique to psychosis spectrum youth and not observed in those with other psychopathology. Exploratory analyses revealed that greater age-related deviation in centromedial amygdala-thalamus connectivity was associated with increased severity of positive symptoms (r=0.19, p=0.01, q=0.05) in psychosis spectrum youth. Conclusion: Using neurodevelopmental growth charts to identify a lack of normative development of amygdala connectivity in psychosis spectrum youth may help us better understand the neural basis of affective impairments in psychosis, informing prediction models and interventions. age-associated between CM amygdala and four the striatum, ventrolateral and Age-associated alterations in CM amygdala-putamen connectivity and CM amygdala-occipital cortex conenctivity as did not these age-associated deviations. Exploratory analyses revealed that greater age-related deviations in CM amygdala-thalamus functional maturation were associated with greater positive symptoms in psychosis spectrum youth. Our results provide a novel view of developmental alterations in functional connectivity in psychosis spectrum, implicating alterations during discrete developmental windows within neural circuits implicated in a wide array of cognitive and emotional processes.


Introduction: Ectopic pregnancy may occur in fallopian tube, ovary or abdominal cavity. This study focused on tubal pregnancy outcome. The return of fertility after operative removal of tubal ectopic pregnancy was examined in 237 women who were admitted to Hospital Sultanah Nur Zahirah (HSNZ) for ectopic pregnancy between 2012 and 2016. The follow-up period averaged six months to four years. Materials and Methods: This was a case control, retrospective non-comparative study. Data collected from HSNZ Human Resources Management Information System (HRMIS). Patient who has no pregnancy or delivery record after six months of ectopic event were contacted via phone. Multivariate analysis was done to identify score for patients who were at risk of recurrence, and who require fertility help. Results: One hundred forty eight women (64%) aged 20-35 years old able to conceive spontaneously after ectopic pregnancy, with the mean-time of 8 months if one tube is patent. Ninety three percents of those who conceived had intrauterine pregnancy, 5% had recurrent ectopic pregnancy. Conclusion: From a multivariate analysis, a scoring system, Recurrent Ectopic Pregnancy (REP) score was made to choose most suitable patient for laparoscopic intervention, preserve fertility or facilitate fertility. Significant REP score of 4/5 suggest laparoscopic salpingectomy with contralateral sterilization to prevent recurrence of ectopic. Patient with REP score 2-3 may have spontaneous conception and REP score less than 1/5 will require further fertility treatment.


This interface device (10) is disposed between an analog connection (a2) of TELECOMMUNICATIONS and a digital connection (d2) of telecommunications. analog dial codes on the analog link (a2) are converted into control codes for controlling a digital interface (12) for telecommunications, attached to the digital link (a2) to provide access to a digital telecommunications network ( 16, 18, 20). Access to the connection (a2) telecommunications is selectively activated by the interface device (10) in response to a password encoded as an analog dial sequence over the analog link (a2). The interface device (10) delays the establishment of the call with a modem (6) connected to the analog connections (a1, a2) for synchronizing the end of the call establishment with a procedure call setup a remote link connected to the network (16, 18, 20).


In healthcare information exchange (HIE) environments, a publish/subscribe system for the selective and dynamic dissemination of information becomes more and more important due to increasing demand for timely and accurate data sharing among healthcare enterprises. Integrating the Healthcare Enterprise (IHE) proposes a general framework for defining publish/subscribe interactions, and a subscription mechanism using the framework. The mechanism relies on simple document metadata matching. However, in most HIE environments the data are disseminated in the format of XML documents. A more sophisticated filtering mechanism is expected to exploit the structure of the XML documents to perform more efficient and more accurate dissemination of information. We have developed an XPath-based filter for IHE XDS documents. In this paper, we describe the XML schema over which the XPath-based filter is constructed, and show the technical viability of XPath-based filter in the formulation of complex queries on the content and the structure of XDS documents.


This paper reports on a randomized evaluation of two teacher incentive programs, which were conducted in a nationally representative sample of 420 public primary schools in Guinea. In 140 schools, high-performing teachers were rewarded in-kind, with the value of goods increasing with level of performance. In another 140 schools, high-performing teachers received a certificate and public recognition from the government. After one year, the in-kind program improved learning by 0.24 standard deviations, while the recognition treatment had a smaller and statistically insignificant impact. After two years, the effect from the in-kind program was smaller (0.16 standard deviations) and not significant; the paper provides suggestive evidence that the reduction may be due to the onset of an Ebola outbreak. The effects of the recognition program remained small and insignificant. The effects differed by teacher gender: for female teachers, both programs were equally effective, while for male teachers, only the in-kind program led to statistically significant effects.


A chemical exchange process that has been thought to be an unrealistic process for uranium-235 enrichment is being reevaluated because of the great improvement recently reported in Japan and France. This separation process should be given close attention as a method which is suitable for the current requirements on uranium enrichment such as resistivity against nuclear proliferation or effective use of uranium resources. In this paper, the ACEP-process (Asahi Chemical Exchange Process) - a newly developed chemical exchange process in Japan - is outlined. Progress in research and development as well as a concept of an enrichment plant based on this process are presented along with appropriate comparisons with conventional chemical exchange processes.


Capillary rheometry data of a range of commercial polyamide engineering materials was obtained from a mould-flow analysis material database, from which melt viscosity data was obtained at different temperatures, which made comparison of the viscosities difficult. In an attempt to make a reasonable comparison between the melt viscosities of the various polyamide materials at different temperatures, it was necessary to obtain the mathematical functions which describe the relationships between: (i) the melt viscosity and the shear rate, (ii) the melt viscosity and temperature and (iii) the melt viscosity and the combined effect of the shear rate and temperature of each of the polyamides studied. Therefore, melt viscosity was modelled as a function of shear rate at the three temperatures (275°C, 295°C and 315°C), at which the viscosities were determined. The function obtained represented smoothed versions of the experimental data, eliminating the experimental noise and enabling the generation of melt viscosity data at the six different shear rates of the original data. It was established that the melt viscosity as a function of shear rate at constant temperature, in the shear rate range 500-700 s m 1 , is incorrectly described by the Ostwald-de-Waele's model, \eta_{\rm T}={\rm f}({\dot \gamma})={\rm K}({\dot \gamma})^{({\rm n}-1)} , while the melt viscosity of the polyamides studied, as a function of temperature, is correctly described by the model \eta_{\dot \gamma}={\rm g}{(\rm T)}={\rm Pe}^{\left (\rm {QT/R}\right )} . But the response-surface melt viscosity is effectively described as a function of both shear rate and temperature by the model: \eta=\vert {\dot \gamma}\vert^{(\rm n-1)}{\rm Ae}^{(\rm ET/R)} . The parameters A, E and n are highly interrelated as they all influence the average melt viscosity. All are temperature sensitive and also, to some degree, shear sensitive.


"TNNOVATORS, disturbers of the peace, of the church, sowers of | heresies and seditions"; "Turners of the World upside down" l L these and like charges were made against those ministers of the Gospel, called by mid-eighteenth century America "New Lights." Minissters of various sects, although chiefly of Presbyterian and Congregational persuasion, the "New Lights" rebelled against the conventional preaching and religious practices of the period, insisted on personal religious experience and "inner light" as essential for every minister as well as for every layman and, in their enthusiasm, brought disturbance and division into staid congregations and presbyteries. Occasionally they were even charged with inciting to treason, because of some utterance from the pulpit or some statement in a pamphlet.


On Friday the 13th of March 2020, my most immediate concern was getting to the supermarket. I hadn't slept well and woke up at 5 a.m. No matter, it allowed me to get my kids off to school early so ...


We examined cardiac catheterization (cath) data of 104 children with VSD and left to right shunt, with 1st cath in the 1st year and a later cath without intervening surgery. 19% had pulmonic stenosis (PS) initially. Of the remaining 84, 20% later developed PS, leaving 67. 12% of the 67 VSD's were small, with right ventricular systolic pressure/left ventricular systolic pressure (RVSP/LVSP)≤ .39, 27% were ½ systemic (RVSP/LVSP .40-.60), 29% were 2/3 systemic (RVSP/LVSP .61-.74) and 32% were nonrestrictive (NR) (RVSP/LVSP .75-1.0). For the 67 without PS, pulmonary artery (PA) systolic pressure fell or was unchanged on later cath in 100%, 89%, 83%, S 57% of the small, "2 systemic, 2/3 systemic and NR groups respectively. Mean PA pressure fell or was unchanged in 100%, 89%, 80%, & 39% respectively. RVSP/LVSP fell more than .10 in 50%, 78%, 83%, & 52% respectively. Thus the defect got smaller in 40/67 for all groups. Pulmonary vascular resistance (PVR) increased in 7/67, and these 7 were all in the 2/3 systemic or NR groups.41 of the 104 patients had 2 caths in the first year. 28/41 never had PS, and of these 28, 14 were NR and 10 were 2/3 systemic. Of the 14 NR, 7 got smaller and 3 of the other 7 increased PVR. Of the 10 in the 2/3 systemic group, 8 became smaller and 2 increased PVR.We conclude that for patients with 2/3 systemic or NR VSD's, it is much more common for the defect to get smaller than for the PVR to increase.


objective To establish a rat ulcerative colitis(UC) model and observe the abnormality of its electrical activity of colon.Methods The rat-models of ulcerative colitis were induced by 2,4-dinitrochlorobenzene(DNCB),an electrode was buried in rats' colon and their colonic electricity was recorded.Conclusion It was found that colon of rat-models developed typical ulceration and colonic electricity was abnormal,the basic electric rhythm(BER) of colon was slowed;extent of contractile electrical complex(CEC) was decreased and the percentage of BER and CEC loaded with peak electricity were markedly lowered.


Background: The modified Lapidus is a surgical procedure for managing moderate to severe hallux valgus, especially in the presence of first tarsometatarsal joint arthritis or hypermobility. It has good long-term results but reportedly can lead to transfer metatarsalgia due to inherent shortening of the first metatarsal. Methods: A retrospective analysis of all adult patients who underwent a modified Lapidus procedure during a 3-year period was performed. Clinical notes were evaluated to look for nonunion or any other complications related to the surgery. Pre- and postoperative standard weightbearing radiographs were used to establish the relative metatarsal length (RML), intermetatarsal angle (IMA), hallux valgus angle (HVA), and distal metatarsal articular angle (DMMA). A total of 69 modified Lapidus procedures were identified, with 32 included in the study. Results: The mean pre- and postoperative RMLs were −0.8 and −4.9 mm, respectively. The average RML shortening due to the procedure was −4.1 (P < .0001). The mean pre- and postoperative IMAs were 15 and 5 degrees, respectively (P < .0001). The mean pre- and postoperative HVAs were 33 and 9 degrees, respectively (P < .0001). One patient reported transfer metatarsalgia, which was attributed to elevation of the first metatarsal. Conclusion: We found a statistically significant degree of shortening of the relative length of the first metatarsal without any clinically significant metatarsalgia. The low rate of transfer metatarsalgia following the modified Lapidus procedure could be attributed to the sagittal plane correction and stability obtained by performing a first tarsometatarsal fusion. Level of Evidence: Level IV, retrospective case series.


The current research is based on the organizational transformation of PT. Bank Mandiri (Persero)in order to improve the performance of the company. New culture adopted by PT. Bank Mandiri (Persero), Tbk certainly affects the future of the company alone. Company is committed to improving the performance and job satisfaction of their employees in pursuit of organizational goals. Several factors have influenced employee performance and job satisfaction, and in this study were limited to two factors, organizational culture & organizational commitment. The present study aimed to test the relationship between organizational culture and organizational commitment to employee performance and to test the effect of job satisfaction on the relationship among organizational culture, organizational commitment and employee performance. The research data was obtained from primary and secondary data through the dissemination of questionnaires to employees, which contained various statements related to the variables studied. The subject of this research is the entire staff of 40 people at PT Bank Mandiri (Persero), Tbk. Data analysis in this study uses moderated regression analysis. The study concludes that organizational commitment has a significant impact on employee performance, while organizational culture does not significantly affect employee performance. Organizational culture and organizational commitment simultaneously impact employee performance. Job satisfaction influences the relationship between organizational culture and performance and job satisfaction is a moderating variable rather than an independent variable


Objectives: Estrogenisoneof theimportantfactorsintheprogressionof breastcancer. CytochromeP450Superfamily(CYPs)plays an important role in the metabolism of estrogen. The CYP1A1 gene has been shown to be involved in the metabolism of estradiol. Several studies have reported a significant association between CYP1A1 polymorphisms and breast cancer. Methods: In the present work, the association between CYP1A1 polymorphism (Thr461Asn) and breast cancer in Guilan province was investigated. The blood samples were obtained from 120 patients and 80 controls. After DNA extraction, specific primers were adapted to amplify the specific fragment using restriction fragment length polymorphism-polymerase chain reaction (RFLP-PCR) and the results were examined through gel-electrophoresis. The product of amplification was digested with restriction enzyme BsmA1. Results: Genotype distributions of the CYP1A1 gene showed no significant difference between patients and controls (P = 0.12, Allele A in patients 0.16, in controls 0.10, Allele C in patients 0.84, and controls 0.9, respectively). Conclusions: The results from this study suggest that the Thr461Asn polymorphism of CYP1A1 gene may not be associated with the risk of breast cancer in the population of Guilan province. Further studies are needed to confirm the role of CYP1A1 gene in breast cancer.


The generally acknowledged sources of renewable energy are wind, geothermal, biomass, solar, hydropower, and hydrogen. Renewable energy technologies are crucial to the production and utilization of energy from these regenerative and virtually inexhaustible sources. Furthermore, renewable energy technologies provide benefits beyond the establishment of sustainable energy resources. For example, these technologies produce negligible amounts of greenhouse gases and other pollutants in providing energy, and they exploit domestically available energy sources, thereby reducing our dependence on both the importation of fossil fuels and the use of nuclear fuels. The market price of renewable energy technologies does not reflect the economic value of these added benefits.


People are living longer lives due to advances in medicine, science, and technology. In the past two decades, the population of those people less than 65 years of age grew 19% while the population of those greater than 65 years rose by 56% (Weinstein & Clark, 1989). By the year 2000, people over 65 will constitute 13% of the U.S. population (Weinstein & Clark, 1994). As a result of increased longevity, hearing loss has become more prevalent (O'Rourke, Britten, Gatschet, & Krien, 1993), as there is a direct correlation between age and hearing loss. Given that a significant percentage of older Americans have hearing loss and that the number of older Americans is increasing, it is clear that hearing health care is important to this segment of society. The provision of hearing health care is particularly important in those areas of medicine that serve the older population, where hearing loss is known to be one of the most prevalent chronic physical disabilities. Rehabilitation medicine is one such area. Unfortunately, many health-care practitioners, including physicians, view hearing impairment as a rather benign problem, viewing it as a non-threat to physical, emotional, or social function (Lavizzo-Mourey & Siegler, 1992). On the contrary, however, hearing loss has been found to impair emotional well-being, social interaction, cognitive assessment, and perceived well-being of affected individuals (Mulrow, 1991; Voeks, Gallagher, & Langer, 1990). It has also been associated with the functional problems of poor general health and reduced mobility (Weinstein & Ventry, 1982). In the health-care setting, people with hearing loss who pretend to understand what is said to them creates a potentially dangerous situation, as case histories and explanations regarding illness, medications, and therapy all rely on verbal interaction (O'Rourk e. al., 1993). Specific to the rehab setting, hearing acuity will have an impact as to how well the individual manages the many types of therapy in which they are involved. Hearing loss is not easily detected by informal assessment alone, and undiagnosed hearing loss can lead to poor communication between the affected person, staff, and significant others. Hearing loss is measurable, treatable, and manageable as long as there are appropriate audiological test protocols in place. Since many people involved in an intensive rehabilitation program are older, it is expected that there would be a need for aural rehabilitation--not only to improve the quality of patient care in the hospital, but more importantly, to improve the quality of life after hospital discharge (Dalzell & Puccia, 1983). While professionals seek to rehabilitate the individual following illness or injury, it is vital that the rehabilitation program is inclusive to incorporate audiological testing and aural rehabilitation into the program. Afterall, how can valid test results be obtained from individuals when they have not correctly heard what was asked of them? How can people fully benefit from any type of rehabilitation when they do not hear well enough to understand, exactly, what is expected of them? In short, how can people effectively socialize and interact with their peers and professionals when they find it difficult to hear and understand what others are saying? This study was undertaken to determine the hearing sensitivity of people admitted to a hospital-based rehab program and to determine how many of those people who have hearing loss use hearing aids. Specifically, the purpose of this study was to describe a large sample of people admitted to a hospital-based rehab program in terms of admission diagnosis, hearing loss, use of hearing aids, self-perceived hearing handicap, and amount of hearing loss by age. We hypothesized that the outcome of this study would clearly support the inclusion of audiological evaluations in the multidisciplinary assessment of people admitted to a rehabilitation unit. …


The aim of the paper is to investigate, design and construct the Global Positioning System (GPS) navigation system, communications bus, and central computer for an autonomous ocean vessel. The objectives were: to interface a GPS receiver to a host processor; to design a communications bus connecting the central computer to the host processor; and to design the central computer. The software to control the GPS receiver remotely from the central computer has been completed. The host processor is now able to request the GPS receiver for any message, and is able to command the receiver to perform different tasks and change current settings. Buffers have been incorporated into the code to increase efficiency. The host processor can now transmit to and receive from the central computer across the communications network. A marine navigational bus standard, NMEA 0183, has been researched and found suitable for this application. Interfaces to the bus have been constructed and tested. The functionality of the central computer has been implemented on an IBM-PC compatible, and is able to control the host processor. This paper aims to inform of the results obtained in the above mentioned areas.


In order to study the kinetic energy level correlation of conduction electrons in small metallic particles, we measured the magnetic field dependence of the Knight shift of 63Cu in copper small particles. We observed the suppression of the anomaly in spin paramagnetic susceptibility in the magnetic field so high that the Zeeman energy is larger than the average spacing of the energy levels. This suppression is explained as that the levels of electrons with opposite spins at the Fermi energy is lost in high fields.


Abstract: We report a case of acute rheumatic fever in a 46-year-old man diagnosed with the assistance of contrast cardiovascular magnetic resonance imaging. This case demonstrates the use of contrast cardiovascular magnetic resonance imaging as a noninvasive method for detecting carditis and contributing to the diagnosis and management of acute rheumatic fever.


This study proposes an incremental extreme extraction method based on the waveform characteristics of ground vibration signals obtained from open-pit mines to investigate the distribution and characteristics of ground vibration from deep-hole blasting. Firstly, an incremental extreme extraction method is proposed based on the waveform characteristics of borehole blasting vibration signals in open-pit mines. The proposed method could extract and screen the extreme values of blasting vibration signals and effectively improve the utilization rate of the data. The space vector of particle vibration is introduced to analyze the angle change between the particle velocity vector and the ground surface when the extreme value increases. Finally, the relation between the particle velocity vector and the angle between the ground plane and the increasing extremum position of several sets of measured signals is studied. Based on the statistical analysis, the results show that the particle velocity in the vertical direction has a significant advantage over that of the other two directions, and the angle between the extreme particle velocity vector direction and the ground plane is primarily distributed in the range of 60°~90°. After an unstable distribution of particle velocities in the transition zone, the particle velocities in each direction gradually attain a relatively balanced and stable attenuation condition as the distance increases. This proves the reliability of the proposed vector analysis of particle velocity in understanding the mechanism of rock blasting.


In future energy systems, storage will have a primary role, allowing smaller generation units. What is more for non-intermittent renewable energy sources such as solar and wind, storage is strictly necessary. The cost of electrical batteries is still very high, so one of the preferred storage technologies is the thermal one. In fact, thermal energy is used both as it is and as a source to be convert it into other forms. Thermal energy storage can increase the efficiency of industrial plants by exploiting waste heat and the efficiency co-generation plants by making the generation independent from the demand curve. Among thermal energy storage phase change materials(PCM) represent an opportunity thanks to their large latent heat that can reduce the size of storages. The main purpose of this thesis is the modelling of phase change material units macro-encapsulated in commercial hot water storage tanks. It starts with a literature review about the different phase change materials for latent heat storage applications and the numerical methods to model them. These methods are tested by launching different simulations of a study case on Comsol. The numerical results are compared to each others and to the experimental results in order to verify which of the methods better models the real case. The best one is then used to model the charge and discharge of a PCM unit in a climatic chamber. The results are then compared with the experimental ones to validate the model and a study on the effects of the different empirical parameters on the solution is done. In chapter 7 two different commercial hot water storage tanks are modelled on Matlab with the finite volumes method and are both validated with experimental results. The first tank has one immersed coil, while the second one has two coils for charge and discharge. These models can be coupled with the one of the PCM-unit to simulate the behaviour of the PCM macro-encapsulated into commercial hot water storage tanks. One of the prospective studies is, indeed, the validation of the model of the PCM-water tank storage system.


,n r r r " 1 = and whenever m n s s r r r " " 1 1 = = (where m n s s r r , , , , , 1 1 " " are irreducibles), then m n = and the j s can be renumbered so that i r is associated to . ) , , 1 ( n i si " = Denote the set of arithmetic functions


A powder metallurgy route based on hot isostatic pressing (HIPing) of tape-cast monotapes was used for the direct fabrication of dense thin sheets (250–300 μm thick) of gamma titanium aluminide (γ-TiAl). Polarized light microscopy revealed a fine-grained microstructure (average grain size ~ 3 μm) but a few isolated larger grains (~20 μm) were also present. The primarily metastable α2 microstructure of the rapidly solidified starting powder transformed to the equilibrium near-γ microstructure during HIPing. Chemical analysis revealed that the dense sheet had a carbon content of 0.13 wt.%, which was only 0.04 wt.% higher than that of the starting powder, but the oxygen content was significantly higher, presumably introduced during the decanning step. The hardness measured using Vickers microindentation technique was 384 + 9 HV. Manipulation of the as-HIPed microstructure was performed by heating for up to 1 hour in flowing argon at temperatures (1170-1385C) below and above the alpha transus (1355°C). Below 1250°C, limited grain growth and no discernable change in the as-HIPed (near-γ) microstructure occurred. Sheets heated to 1320°C and 1365°C had a duplex microstructure of γ and α2 grains, with some lamellar grains. Except for a thin surface layer (20–30 μm thick), the microstructure of the heat-treated sheet was uniform, but a fully lamellar microstructure was not achieved even after heating for 1 h at 1385°C.


IE E E S P E C T R U M • M ar ch 2 0 0 1 T en years ago, Linus Torvalds was a shy undergraduate at a Finnish university, his Linux operating system did not exist, and few took seriously the idea that large amounts of quality software could be developed outside the closed framework of commercial companies. Today, open source and free software runs most of the Internet, and Linux is the fastest-growing operating system, prompting a sea change in how many companies do business. Glyn Moody charts this rapid transformation in his book Rebel Code: Linux and the Open Source Revolution and tells how chance and fortune combined with the Internet and the availability of cheap processing power to make the impossible possible. IEEE Spectrum's Stephen Cass talked to him to find out more.


No contradiction can exist between the economic and the political aspects of a revolutionary conception, even supposing the clearest organic and functional demarcation between them. The same is true for any reactionary conception. Hence the present interpenetration, the agreement and collaboration between unions economic organs and political parties ideological organs gives us the key to understanding both, from whichever side one looks at the matter. This statement proceeds from an old and unalterable principle, more than proven by reason and verified by men in the course of a thousand years' experience : every idea or political action arises from an economic foundation which then plays both a controlling and determining role. In the course of this work we will examine, under different aspects, the interpenetration of politics and economics and evaluate unions by taking a look at how they presently function. Unions first appeared as defensive organs of the working class, faced with sub-human conditions of work, presenting themselves, on the industrial plane, as extensions of the old brotherhoods and corporations. On the basis of their aspirations unions do not even reach the level of reformism. Reformism, utilizing ideological and economic analyses, claims to demonstrate that, by means of capitalist democracy, it would be possible to attain socialism through a legal evolution and without any need for revolutionary acts. For unions there was never a question of either evolution or revolution, still less of socialism. Unions go no further than attempting to obtain, for the exploited worker, conditions of labor which are less intolerable and less humiliating, but also, as time has demonstrated, more profitable for capital. In spite of this limitation the early unions were organs which, if not revolutionary, at least had a working class spirit and a sound composition compared to the corruption and false class character of today's unions. At the end of the 19th and the beginning of the 20th century a so-called revolutionary unionism (syndicalism) appeared. This was an eclectic doctrine adapted to the situation then prevailing, drawn from the marxist conception, the so-called a-politicism of anarchism, and the strictly economic claims made by the old trade unions. There is no paradox in the fact that the period of the greatest influence and the strongest thrust of this type of unionism coincided with the apogee of reformism. Sorel and Bernstein, besides being contemporaries, had more points in common than differences. While Sorel offered, in syndicalism, the panacea to the problems of historical development, Bernstein and his tendency saw in parliamentarism, and even in the necessities of capital accumulation, the happy mechanism of a certain and harmonious evolution towards socialist society. In reality revolutionary syndicalism and reformism were united by the same bonds to the formidable economic drive of the bourgeoisie. This was the period in which the bourgeoisie attained the zenith of its civilizing possibilities, granting the greatest amount of liberty and illusions to those who, without completely escaping its ideo-economic complex, leaned to the left. For this reason the political bankruptcy of 1914 would carry with it the syndicalists and reformists. Even the Spanish C.N.T. was not an exception, although the military neutrality of Spain spared it the capitulatory phrases and attitudes of the French C.G.T.; its particular bankruptcy, as we will see later, took place at the moment of the proletarian revolution in 1936-1939. The numerical strength and the social weight of the unions has grown continually since 1914 and if in some countries, like France, their numerical strength has considerably diminished in the course of the last few years their importance has continued to grow. It has been said that the disaster of 1914 was necessary for the unions to really come into their own. This is because until that time capitalism feared the unions as a destructive force and had not yet seen except perhaps in England the collaborative role that unions could play. But since the end of the first world war numerous experiences of « worker's control » in the factories have surprised the capitalists by their satisfactory effects. « Worker's control » has attenuated the struggle of workers against capital, facilitating the operation of the factories and above all increasing output. The unions stood out not only as defenders of the fatherland that specifically capitalist entity but as effective collaborators in the mechanism of exploitation itself. That made their fortline and opened as yet unsuspected horizons to them. However, it was during the years 1936-1937 years which for many reasons were a very important landmark in the history of the international workers' movement that the unions took on their definitive orientation. In this period they displayed the qualities thanks to which they have become one of the most solid pillars of capitalist society.


The bright F8 V solar-type star upsilon Andromedae has recently been reported to have a system of three planets of Jovian masses. In order to investigate the orbital stability and mutual gravitational interactions among these extrasolar planets, both forward and backward integrations from the latest observed orbital elements for all three planets' orbits have been performed under the coplanar assumption. We reconfirm that the middle and the outer planet have strong interaction leading to large time variations in the eccentricities of these planets, which was shown by the previous studies. However, we discuss the validity of the ignorance of the innermost planet. We argue that this planetary system is likely to be stable and oscillate around current orbital elements since it was formed. We suggest that one possible way to produce these orbital elements: the innermost planet has very low eccentricity but the outermost planet has high eccentricity could be the interaction with the protostellar disc.


The method given in [1] recognize abbreviations and their definitions in one text (refereed texts are not examined). The method iterates through each word sequentially in the text. For each word, the method check the word against a set of rules to tell if it is an abbreviation (section5). If it is an abbreviation, it is parsed into abbreviation pattern. Abbreviation pattern reveals the structure of the abbreviation. The pattern consists of a sequence of abbreviation elements which can a letter, non-alphanumeric character or a number. To look for definition, the method assume that definition appear around the abbreviation (within the search space defined in section 6). (It only search for definition in


We studied correlations between the superconducting gap features of Te-substituted FeSe observed by scanning tunnelling spectroscopy (STS) and break-junction tunnelling spectroscopy (BJTS). At bias voltages outside the superconducting gap-energy range, the broad gap structure exists, which becomes the normal-state gap above the critical temperature, Tc. Such behaviour is consistent with the model of the partially gapped density-wave superconductor involving both superconducting gaps and pseudogaps, which has been applied by us earlier to high-Tc cuprates. The similarity suggests that the parent electronic spectrum features should have much in common for these classes of materials.


The Active Directory (AD) is the catalogue management of Windows 2000.It is expandable and layer upon layer catalogue structure.it store information of network objects.you can manage the catalogue information much easierly and design the network even more convenientily and flexily by using AD.This paper introduces the conception,structure of AD,setup and manage deeply and simply application.


Arteriovenous malformations or hemangiomas are rarely reported complications postrhinoplasty. While surgical lasers are gaining increasing use in the treatment of other etiologies of arteriovenous malformation, the potential for unacceptable cosmetic results justifies examination of other, more traditional techniques for repair of these difficult vascular problems. This case presentation details a successful surgical approach to treatment of the postrhinoplasty arteriovenous malformation and outlines the clinical judgments and findings used to rule out use of the laser as a primary surgical modality.


An experimental and theoretical investigation was made of the magnetoacoustic resonance in a cylindrical argon plasma. The plasma, which was immersed in an axial magnetic field, was generated by a discharge current and was highly ionized. The wave was excited at the plasma boundary by an auxiliary B/ sub z/-coil and traveled radially to the center of the cylinder. Linearized theory was used to obtain the solution for the general case of partial ionization. The solutions for resonance curves and radial distribution of the wave magnetic field are presented with the degree of ionization as a parameter. Measurements are shown to be in good agreement with theory. It is shown that magnetoacoustic resonance can be used as a diagnostic method for determination of the ion density of a partially ionized plasma. Densities measured spectroscopically from Stark broadening of the H/sub BETA / line were in agreement with densities measured with magnetoacoustic resonance within the errors. The decay of the ion density, which followed the cooling of the plasma, is discussed. (auth)


Chinese allusions of New Year and the Lantern Festival used by M.A. Bulgakov in the 6th chapter of the novella "The Fatal Eggs" are studied. White and black ritual magic, mythological images of Chinese agricultural calendar are considered from the perspective of Chinese festive culture and its carnivalization: Peach tree, "Fire judge", "White inconstancy" and "Black inconstancy", "Purple girl". The mythopoetic analysis of the novella involves a "fantastic and satirical" novel by a medieval Chinese writer Wu Cheng'en "Journey to the West" (1590). It is shown how M.A. Bulgakov inscribes this unusual, exotic, religious work that captures the basics of Chinese culture in his text. In addition to the mythological content, the allusions analysis sphere on the Chinese text involves the image of a medieval Chinese official, Chinese etiquette, a celebratory feast, street and areal decorations of the spectacle and jollification. The miracle-play character of the novella is researched. Not only the rituals of summoning the gods, demons, and spirits of the dead are described, but also the traditional for all the miracle-plays initiation of the "neophyte", one of the main stages of which is the catabasis (descent into hell), called by C.G. Jung as the archetype of "the knight's departure into the dark". The main character's path to the Chinese tartarus of the novella by Professor V.I. Persikov turns out to be such a catabasis, shown in a parody key. Close attention is paid to such a modernist method of depicting Russian reality as the method of collision/interference of times. Chinese carnival "madness" is becoming a real Russian madness associated with the reforms of the national economy. Therefore, a special place in the study is giv-en to the satirical means analysis of influencing the viewer: elements of eccentricity, comedy play, parody and grotesque. In this field of Bulgakov's caustic satire lies, we think, the image of the "the world's first socialist state" founder V.I. Lenin and the internal policy of the leaders who replaced him, announced the beginning of the Russian peasantry destruction era and the beginning of the collectivization and agriculture mechanization era. The phantasmagoria genre, manifested in the mass hysteria of Muscovites and blazing fires from burning mountains of dead chickens, also strengthens the satirical character of the story.


In the aftermath of the devastating earthquake in Turkey in the aftermath of the COVID-19 pandemic, which has affected all lives globally, online education continued in 2023. This situation has shown that online education is an indispensable alternative at a local or national level for various reasons in the coming years. Past research has demonstrated the potential of online education to bring about changes in students' daily routines. Just like online education, fasting during Ramadan, one of the Muslim societies' religious practices, affects individuals' daily lives in various ways. By conducting a comprehensive analysis of university students' sleep habits during Ramadan and considering the role of online education, this study aims to provide valuable insights into the factors contributing to these changes and provide evidence-based recommendations for maintaining optimal sleep quality. Seventy-four university students from two universities in Turkey were evaluated using the Pittsburgh Sleep Quality Index (PSQI) before and after Ramadan. The results indicated a significant deterioration in subjective sleep quality, sleep latency, sleep disturbances, daytime dysfunction, and overall sleep quality (global PSQI score) during Ramadan. However, no significant changes were observed in sleep duration, habitual sleep efficiency, and sleep medication usage. The findings underline the need for tailored strategies to support university students' sleep hygiene during Ramadan, particularly in the context of online learning.


The nearest star α Centauri is a triple system. The star α Cen, one of the pointers to the Southern Cross, is itself a −0.3 mag visual binary consisting of a α Cen A, a G2V star popularly considered to resemble the Sun, and α Cen B, a KOV star. The orbital period is 80.089 years, the semimajor axis is 23.5 AU, the distance 1.34 pc, the masses are 1.11 and 0.92 (±0.03) M⊙ (Kamper & Wesselink 1977). The third star, Proxima Cen (V645 Cen) is a faint common proper-motion companion separated from α Cen AB by about 2°. It is known to most people only by virtue of being slightly closer to the Sun than is α Cen A, and therefore actually the closest star.. This 11th mag flare star is undoubtedly coeval with a α Cen AB, but being the least massive by a considerable margin, may have been ejected from the system shortly after formation.


Objective
To explore the precision, efficiency and safety of robot-assisted stereoencephalography (SEEG) electrode implantation applied in epilepsy surgery.

Methods
A retrospective analysis was conducted on 23 patients of refractory epilepsy who were admitted to Beijing Institute of Functional Neurosurgery, Xuanwu Hospital of Capital Medical University from February 2018 to June 2018 and underwent robot-assisted SEEG electrode implantation ('robot' group). A total of 25 refractory epilepsy patients admitted from October 2017 to January 2018 underwent CRW stereotactic apparatus-guided SEEG implantation and served as control ('CRW' group). Continuous thin-slice CT was conducted post operation in each case, based on which the distance between the actual and planned target of each electrode trajectory was measured and set as operational deviation.Operational duration for each electrode implantation and incidences of postoperative complications were documented. The parameters as above were compared between the 2 groups.

Results
In the 'robot' group, a total of 179SEEG electrodes with 2 642 contacts were implanted in this series (23 cases), with the median of 8 (5-10) electrodes with 120 (76-136)contacts in each patient.In the 'CRW' group, 25 patients underwent implantation of 172 electrodes with 2 520 contacts, with the median of 7 (6-9)electrodes with 100 (60-128) contacts in each patient.The operational deviation of each electrode was 1.4 (0.4-9.3) mm ('robot' group) and 1.4 (0-4.6) mm ('CRW' group), respectively, which had no statistical difference (P>0.05). Compared with 'CRW' group, the 'robot' group had significantly shorter operational duration[8(5.9-12.8) min vs. 14.7 (10.3-18.5) min, P<0.01] for each electrode implantation. In the 'robot' group, there were 2 cases (8.7%) of asymptomatic intracranial hemorrhage. No cases of infection or other complications were observed. In the 'CRW' group, there were 1 case (4.0%) of intracerebral hemorrhage causing contralateral paralysis, 1 case (4.0%) of asymptomatic hemorrhage and no cases of other complications.

Conclusions
Robot-assisted technique seems to be able to remarkedly increase the efficiency of SEEG electrode implantation with relatively good precision and safety, which could thus be recommended for clinical use and promotion.

Key words:
Epilepsy; Neurosurgical procedures; Robot; Stereotaxic techniques; Intracranial electrode


We describe the use of surface-deposited nickel nanoparticles to enhance the fluorescence signatures of fluorophores. Different density Ni nanoparticulate substrates were fabricated and characterized using both AFM and optical absorption techniques. When fluorophores were placed in close proximity to the substrates, metal-enhanced fluorescence (MEF) was observed. The wavelength dependence of the metal-enhanced fluorescence corresponded with numerical finite-difference time-domain simulations also showing a broad range (500−800 nm) for the enhanced electric field of Ni nanoparticles as compared with traditionally ≈400 to 500 nm for the widely used Ag nanoparticles. This broad wavelength range for an enhanced electric field enables nickel nanoparticles to enhance near-field dipoles in the visible to the infrared region. In addition, the decay times of fluorophores were also reduced near the Ni substrates, suggesting both an enhanced electric field and a plasmon-coupling component are the mechanisms for fluo...


The need for increased computational speeds beyond what most physical devices can deliver-has led machine designers to explore parallelism in computer architectures. New hardware may exploit the parallelism inherent in application programs at any of several levels, including single operations (data flow), loop vectorization (pipelining), subroutine tasks (multitasking), and user Jobs (independent uniprocessing). The Cray X-MP-2 is a multiprocessor system capable of two types of operations: simultaneous scalar/vector processing of independent job streams and .simultaneous scalar/vector processing of independent tasks within one Job. Consequently, it is capable of exploiting more than one level of parallelism at the same time. This article presents an overview of the hardware and software that .support multitasking on the X-MP and describes the programming conisiderationis required to write multitasking programs. Although the Cray X-MP-2 has the same physical appearance as the Cray-1, the chassis niiw contains two processors, each an enhanced version of the Cray-I CPU. Moreover, a combination of several architectural changes2 contri'butes to anl improved performance in each processor (see Table 1 for major differences). The clock period is reduced from 12.5 to 9.5 ns, thereby quickening the issue and execution of instructions. The number of memory ports per processor is increased from one to four, allowing two memory reads, one memory write, and 1/0 to proceed simultaneotusly in each processor. Finally, the "chaining" mechanism, which allows results of prey ious operations to enlter the computational pipeline, is improved by eliminating the fixed-chain slot time (the clock period when links are put together). 3 Chains of operations can now include both memory reads and writes and arithmetic computations , and intermediate results automatically enter the pipeline as soon as they become available. Figure 1 illustrates the overall system organization. The mainframe communicates with the front-end system and external data-storage devices through the 1/0 subsystem. An optional solid-state storage device, SSD, provides an internal, second-level store. Both processors share a central memory. Each Liser's program and data area in memory are separated by individual base and limit registers. Special hardware enables the efficient and coordinated application of multiple processors to a single job. All processors assigned to a job share a unique set of binary semaphore and data registers. The semaphore registers allow the two processors to exchange signals indicating that processing should begin, should wait, or has been completed. Semaphore deadlock, a programming bug that cautses each processor to wait on the other, …


To study the real perform situation of the medical instrument quality system among the medical instrument manufacturing enterprises in Guangdong Province,we reviewed the quality system in nearly 300 enterprises of second-class medical devices in 2007,2008 and 2009 respectively. The results showed that it was very common that these enterprises failed to match with the demand of quality system during the process of manufacture. What caused the results? Meanwhile,what problems should be concerned while the enterprises established and maintained the quality system? To solve these doubts,we comprehensively analyzed the quality evaluation system and the system review for 3 years during 2007-2009,and put forward some recommendations and suggestions to improve the quality evaluation system as a reference for the enterprises.


What are the personal characteristics required to be a successful entrepreneur? Before making the personal sacrifices required to start and build a major enterprise, would-be entrepreneurs should engage in serious soulsearching to be sure they have what it takes to thrive in the toughest jungle of the business world. To assist in this introspection, the following guidelines have been prepared by principals of Venture Founders Corporation (VFC). Founded in 1970 to design and apply new approaches to venture development and financing, VFC serves investor clients both in the United States and in the United Kingdom. These clients have committed capital to funds that finance new and young ventures that are found, evaluated and assisted by VFC. Venture capitalists say they prefer a grade A entrepreneur with a grade B business idea to a grade B entrepreneur with a grade A idea. And it is generally a strong management team, not a lone entrepreneur that they back. With that in mind, there are some initial questions that would-be entrepreneurs must consider: Do I have adequate commitment, motivation and skills to start and build a major business—to be a successful entrepreneur? Does my management team have the necessary skills to enable us to succeed in building a particular venture? And finally, do I have a viable idea? If these questions can be answered affirmatively, then it may be wise to consider developing a business plan and beginning a search for venture capital. This, however, is only the first step of the entrepreneurial self-examination process.


Objective: Cognitive Estimation Tests (CETs) are used to assess decision-making. Previous versions include culturally- biased questions likely to disadvantage certain sections of the population. This study aimed to develop a new culture fair questionnaire and assess its reliability and validity.
Method: A 30-item questionnaire was developed and assessed for culture fairness. A normative range of answers was gathered, and a scale developed to define level of deviation from typical responses. Performance in a group of people with brain injury was compared to a matched group of healthy controls. Those with brain injury deemed able to make significant life decisions were compared with a group considered to lack this capacity, to determine whether this test may be useful when assessing decision-making capacity. Correlational analyses were conducted to determine whether there was a relationship between the test and performance on the Dysexecutive Questionnaire (DEX), a measure of everyday executive functioning. Test-retest reliability was examined with 30 of the normative sample.
Results: Results confirm previous literature showing that those with brain injury perform significantly worse than healthy controls. The test did not discriminate between patients with and without capacity to make important decisions, did not significantly correlate with the total score on the DEX and demonstrated relatively poor consistency. Conclusions: Based on these results, CETs do not appear to be reliable or valid enough for use in clinical assessments. A sub-set of the most sensitive items may prove useful, but further work is required to examine the reliability and validity of this item subset in new samples.


The MLR family of COMPASS-like complexes are histone methyltransferase complexes that are associated with the activation of gene enhancers. In D. melanogaster, Cara mitad (Cmi, also known as Lpt) and Trithorax related (Trr) are central subunits of a complex orthologous to mammalian Lysine methyltransferase 2 C and D (KMT2C and KMT2D, also known as MLL3 and MLL2/4) that catalyze H3K4 monomethylation. Previous studies have demonstrated that mutations in these genes are associated with cancer and developmental disorders, but the mechanisms by which these alterations contribute to disease states are unknown. The Cmicontaining COMPASS-like complex and orthologous vertebrate complexes have been identified as necessary co-regulators of multiple critical developmental signaling pathways, and knockout experiments have demonstrated that these complexes are necessary for development and viability. My research shows that Cmi has a distinct expression pattern in developing tissues, and the knockdown abrogates normal developmental patterns in both the embryo and ovary. Ubiquitous shRNA mediated knockdown of Cmi in the embryo results in early embryonic lethality, and shRNA expressed in certain ovary tissues results in reduced egg-laying efficiency and incomplete ovary development. By elucidating the embryogenesis stage at which the COMPASS-like complex performs its function as well as its requirement in the female germline, future experiments aimed at revealing gene targets can be narrowed to these key developmental periods.


The stability of the stressed samples of pseudoephedrine hydrochloride sustained-release tablets was evaluated after acid, alkali, hydrogen peroxide, heat and light treatment. Reversed-phase high-performance liquid chromatography for the simultaneous determination of impurities associated with the tablets was developed and validated. The examined samples were analyzed on a C_ 18 column (250 mm×4.6 mm, 5 μm) and a mobile phase containing 0.5% triethylamine(adjusted the pH to 3.0 with phosphoric acid)-methanol(9∶1), a flow rate of 1.2 mL/min and UV detection wavelength of 257 nm. The degradants generated during the test were well detected, suggesting that HPLC can be used for the quality control of pseudoephedrine hydrochloride sustained-release tablets.


In §§138–47 of the Basic Laws of Arithmetic, Frege attacks the notion that mathematical objects can be 'created', criticising Stolz, Hankel, and Dedekind directly, and Cantor and Hilbert indirectly. This paper tries to assess exactly what Frege's criticism criticises, concentrating particularly on Frege's opposition to Dedekind and Hilbert. Frege's ostensible target is arbitrariness, and the need for consistency proofs and the method of achieving them. However, the analysis here argues that the real target is the hidden existential assumptions which are called on, as well as the attempt to avoid what Frege would consider proper definitions. This is then compared to Frege's description of his own procedure. In the light of this, the paper concludes that Frege's criticism is unfair, that he attacks these other mathematicians for not doing what he himself is unable to do. At the end, attention is also drawn to another attack on the idea that we create mathematics, that of Gödel. Gödel's core concerns and core arguments differ from Frege's, many of them being rooted in the various incompleteness phenomena discovered long after Frege's work. Nevertheless, there are parallels, which it would be instructive to pursue.


With the reform of the fishing system and the changing of the fishing vessels' possesion construction, the number of national fishing vessel reduced but individual ones increasesed. The fisherfolks are lack of qualities, they kniw little about marine laws, especially collision regullations, which caused the sailing area become bad and marine accidents increase. Through the research of the big marine accidents and the analysis of the people, machinery and environment, this article brings forward some precautions of preventing marine accidents.


Three concentrate mixtures E1, E2 and E3 prepared by incorporating cocoa pod shells (20%), cocoa husk (30%) and cocoa pod shells + cocoa husk (20% each) respectively, were compared with a conventional concentrate mixture (C) by feeding to four groups of bullocks. The DCP content of mixtures C, E1, E2 and E3 was 14.00, 11.11, 12.81 and 11.51% respectively. The corresponding mixtures had 79.50, 58.35, 66.16 and 61.28% TDN. The DCP and TDN contents of experimental groups were lower (P<0.05). Inclusion of cocoa byproducts as ingredient of concentrate diet reduced the cost from Rs. 217 to Rs. 175 per 100 kg. However, factors responsible for repressing digestibility of nutrients by cocoa byproducts need further study.


This is a statement by Roberto Garcia-Lopez at the meeting of July 12, 2001 concerning the Country Assistance Strategy progress report, the Programmatic Financial and Public Sector Adjustment Loan and the Agricultural Reform Implementation Project for Turkey.


Many genetically multi‐modified donor lines for xenotransplantation have a background of domestic pigs with rapid body and organ growth. The intrinsic growth potential of porcine xeno‐organs may impair their long‐term function after orthotopic transplantation in non‐human primate models. Since growth hormone is a major stimulator of postnatal growth, we deleted its receptor (GHR‐KO) to reduce the size of donor pigs in one step.


The phosphatidylinositol 3‐kinase (PI3K)/Akt pathway is important for tissue proliferation. Previously, we found that tissue regeneration after partial pancreatic resection was markedly attenuated in aged mice as compared to young mice and that this attenuation was because of an age‐dependent reduction of PI3K/Akt signaling in the pancreatic acini; however, the mechanisms for the age‐associated decline of pancreatic PI3K/Akt signaling remained unknown. To better delineate the mechanisms for the decreased PI3K/Akt activation with aging, age‐associated changes in cell proliferation and PI3K/Akt signaling were investigated in the present study using in vitro primary pancreatic acinar cell cultures derived from young and aged mice. In response to treatment with insulin‐like growth factor 1 (IGF‐1), acinar cells from young but not aged mice showed increased activation of PI3K/Akt signaling and cell proliferation, indicating that intrinsic cellular mechanisms cause the age‐associated changes in pancreatic acinar cells. We also found that the expression of PI3K p85α subunit, but not IGF‐1 receptor or other PI3K subunits, was significantly reduced in pancreatic acinar cells from aged mice; this age‐associated reduction of p85α was confirmed in both mouse and human pancreatic tissues. Finally, small interfering RNA (siRNA)‐mediated knockdown of p85α expression in acinar cells from young mice resulted in markedly attenuated activation of PI3K/Akt downstream signaling in response to IGF‐1. From these results, we conclude that exocrine pancreatic expression of PI3K p85α subunit is attenuated by aging, which is likely responsible for the age‐associated decrease in activation of pancreatic PI3K signaling and acinar cell proliferation in response to growth‐promoting stimuli.


In this article, I describe my narrative walking project, StoryWalks, as a methodology that underscores the concept of movement in relation to place-based narratives. I describe several community member's walking narratives, theorizing movement through Deleuze and Guattari's concept of the refrain and through Donna Haraway's concept of storytelling as open signification and materialization in order to think about the various ways in which walking with stories is an entanglement of memories, place-based inquiry, history, future goals, and imaginings that matter for an ethnic and racial politics of place, identity, and belonging. I highlight storytelling through walking as an affective production of political, social, and cultural formations within communities.


A striking feature of the radiation belts is that values of observed electron fluxes and modeled phase space density (PSD) vary by several orders of magnitude. This extremely wide range may present certain problems for standard data assimilation methods, such as the Kalman filter and its various implementations. In this study, we rely on log-transformed PSD and subsequent nonlinear modifications to Kalman-filter—type methods, to make it more efficient for assimilating data in the radiation belts by using a 1-D diffusion model and observations from multiple satellites. We present sensitivity simulations using synthetic data, as well as actual satellite observations using the conventional data assimilation algorithms, on the one hand, and algorithms developed in this study, on the other.


The present invention relates to a three planetary gear with two clutches of a dual mode, a hybrid electric vehicle, to increase the efficiency by making it possible to convert a mode more than a predetermined speed the power transmission using the device, Two motors 110 '(120' ', but includes a motor 1 110 and a single planetary gear 210' at the same time for connecting a) a "ring gear (213 a), the planetary gear 210, the ring gear connection, the axle (500 of the vehicle 213 'to) and, the connection, the carrier (212 engine 400, a), conventional hybrid electric connecting, the sun gear (211 motor 2 120' in) powertrain of the car has an energy cycle occurs as the vehicle speed rises, the reverse speed of the generator, and the energy circulation is much higher quality bar had the disadvantage of the system's efficiency decreases rapidly, Two motors, three planetary gears, but having two clutch, connecting the motor 1 to the sun gear of the planetary gear 3, and connects the engine to the ring gear of the planetary gear 1, the sun gear and the connection of the motor 2, the planetary gear 1 and, the connection to the axle of the vehicle and the carrier of the planetary gear 2, the planet gear clutch on either side of the ring gear 1, according to the present invention as claimed the like by connecting a second mode at a speed higher than the set speed, using the clutch of the conversion, by it is possible to drive by selecting a high-efficiency mode in the period and higher order in interval lower order, by preventing the energy circulation through the mode conversion from the higher speed can be used for both the motor and the battery of low capacity compared to conventional methods, and by mode conversion in a high degree in effect it can be obtained such as being able to reduce the speed of the motor. Hybrid electric vehicle, the power transmission device, the dual mode, the planetary gear, the motor, clutch


A low-rate, low-pressure stimulation technique using a new surfactant retarded, acid-in-oil emulsion has been found effective in providing better sustained production increases than previously obtained in stimulations using 15% and 28% hydrochloric acid in wells having high-temperature, low-permeability, carbonate formations. A fracturing technique also using the emulsion provided significant initial production increases, but rapid declines occurred in most wells. The results of 22 treatments using the low-rate, low-pressure technique and 12 stimulations using the fracturing technique are presented, and are compared to 80 previous treatments using 15% and 28% hydrochloric acid in wells having similar conditions.


Venlafaxine belongs to a group of Antidepressant with a novel chemical structure. In these studies describes a simple, accurate, precise and cost effective UV-visible spectrophotometric method for the estimation of Venlafaxine hydrochloride in bulk and pharmaceutical formulations. The method is based on the measurement of absorbance of Venlafaxine hydrochloride solution in 0.1N NaOH at 225 nm. The method obeys Beer's Lambert's law in the selected concentration range 5–25 μg/ml in selected solvent. The slope, intercept and correlation coefficient were also calculated. Results of percentage recovery study shows that the method was not affected by the presence of common excipients in tablets. The parameters like linearity, precision, accuracy were studied according to International Conference on Harmonization (ICH) guidelines. The developed method was validated in terms of accuracy, precision, linearity, limit of detection and limit of quantitation which proves suitability of proposed method for routine estimation of venlafaxine hydrochloride in bulk and pharmaceutical formulations.


In this paper we have studied how barrier crossing dynamics is affected by colored additive non-Gaussian noise if the barrier fluctuates deterministically. Our investigation indicates that resonant activation(RA) is either enhanced or it becomes robust if noise characteristic is deviated from the Gaussian behavior. We find that additive colored non Gaussian noise can induce the RA-like phenomenon. Another interesting observation is that the turnover behavior persists even in presence of barrier fluctuations at finite rate. Finally, it is observed that mean first passage time(MFPT) decreases with increase of non-Gaussian characteristic of the additive colored noise for a given noise strength and noise correlation time and ultimately reaches to a limiting value. The limiting value remains almost the same if the barrier fluctuating frequency is zero or far from the resonant condition. But near the resonant condition the mean first passage time initially decreases and then increases passing through a minimum as the non Gaussian parameter grows.


The invention discloses an automatic control system of a sludge deep dewatering overall process and a treatment method. The automatic control system comprises a sludge pre-concentration control system, a sludge tempering control system, a sludge deep dewatering control system and a mud cake transmitting control part. According to the invention, the whole sludge deep dewatering process is controlled on the basis of an optimization algorithm. The design concept of the automatic control system is as follows: the operation cost in a boundary range set by a user is always lowest and the total property is maintained optimal. The automatic control system has the advantages of providing the real-time monitoring for a sludge conditioning and deep dewatering integrated process, ensuring the lowest dose quantity and the maximum treating capacity in a set target range, enabling a mud cake to accord with the set requirement, and guaranteeing the stable and continuous optimal operation.


In order to solve the problems existed in MAN and fulfill the requirement on full-service operation from China Mobile,the service types,characteristics and development of a MAN in full-service network are analyzed.The future evolution strategy and structure of the full-service of MAN are discussed,while balancing the existing network equipment,resources and the traditional business of evolution.The complementary strengths in the application of several optical network technologies are developed,the application of PTN(packet transport network),PON(passive optical network) and other optical network technology in the full-service MAN is studied.A design model and construction scheme of the full-service MAN can be established.


Recently, large population-based studies gain increasing focus in the research community. Epidemiological studies acquire numerous data by means of questionnaires and examinations. Many of these studies also collect imaging data, for instance, magnetic resonance imaging or ultrasonography from hundreds or even thousands of participants. Here, we consider several on-going epidemiological studies conducted in Europe as well as challenges of subsequent image analysis and visualization of heterogeneous data, which were obtained within these studies. In particular, the main focus is on airway extraction tasks and the visual analytics problems. Available solutions and future directions for computer science specialists are presented and analyzed in terms of user-friendliness, speed, and efficiency.


October 2013 was not a great time to be on the health care reform team in the Obama White House. The rollout for healthcare.gov--the web site that had been set up for the federal insurance exchange mandated by the 2010 Patient Protection and Affordable Care Act (aka Obamacare)--had been bungled, with only a few thousand sign-ups a month after the site's launch. Pressure was growing for the administration to appoint a high-profile manager to coordinate interagency efforts to solve the technological problems, improve communications, and implement the immense and complex health care legislation to give Americans plenty of time to sign up for new insurance plans before the December 23, 2013, deadline. This kind of bureaucratic solution to a major, salient policy challenge was not unique; indeed, it has been so commonplace over the past several decades that the phenomenon has its own term: czar. From managing the war on drugs to overseeing efforts to avert potential Y2K disaster, czars have long been a preferred response to coordinating policy action that required cooperation across the myriad agencies, offices, and departments of the federal government. Czars have not always been an uncontroversial administrative solution, however, and no president knew more than Barack Obama just how contentious the usage of presidential policy czars really could be. Following his 2008 defeat of Senator John McCain (R-AZ), controversy grew over not only the new administration's alleged overreliance on czars, but also whether the staffing practice itself was constitutional (Vaughn and Villalobos 2012). Several years later, the furor over czars in the Obama White House has largely subsided, but the czar phenomenon itself remains cloaked in misunderstanding. In this article, I attempt to resolve much of the uncertainty and unease surrounding the roles policy czars have played and continue to play in the contemporary presidency. In doing so I first discuss what constitutes a czar. I then examine why czars have been controversial and, in light of that controversy, provide a theoretical explanation for why presidents continue to use them. Finally, I conclude with a discussion of the key factors involved in successful czar policy leadership and how presidents can better utilize their czars, suggestions that can help enhance presidential success while minimizing public controversy. Defining "Czar" The term "czar" has been bandied about enough by politicos that it has become accepted shorthand for an influential administration official involved in a central policy area. For example, former George H. W. Bush deputy press secretary Alixe Glen notes a czar is "someone who can run it all. In a town like Washington that has so many fiefdoms and committees with long acronyms, calling someone simply a 'czar' gets the point across" (Trausch 1989). Obama administration spokesman Tommy Vietor sounded a similar refrain as he sought to tame the aforementioned staffing controversy in the administration's early days: "The term 'czar' is largely a media creation to make jobs that have existed under multiple administrations sound more exciting. Every president since Nixon has hired smart and qualified people to coordinate between agencies and the White House" (Markman 2009). This opinion appears to be shared across the ideological spectrum, as Gene Healy (2009) of the libertarian CATO Institute suggests that "'czar' is a media-coined, catchall term for presidential assistants tasked with coordinating policy on issues that cut across departmental lines" and Bradley Patterson (2009)--whose government service included stints in the Eisenhower, Nixon, and Ford administrations--has testified that "'czar' is not an official government title of anybody; it is a vernacular of executive branch public administration, harking back--in one account--at least to the Coolidge years. It is a label now used loosely hereabouts, especially by the media. …


The self-organizing maps is an unsupervised learning algorithm.This algorithm shows poor robust and reliability when the distribution of study samples has many states and becomes highly nonlinear.The study based on kernel function,performing a nonlinear data transformation into some high dimensional feature space,increases the probability of the linear separability of the patterns within the feature space.But be aimed at the different data,the classification effect of various kernel functions is different.So the choice of kernel function is depend on the questions.A tunable kernel function algorithm which based on the SOM network is proposed.By studying and adjusting modulus which genetic algotithm produces,the effect is better than the result by using single kernel function.


Unrecognized cognitive disorders present ethical and logistical challenges for consenting older adults undergoing surgery. Twenty percent of adults aged 65 years or older have mild cognitive impairment or dementia, and the prevalence may be higher in perioperative patients. There is little literature on the epidemiology of preoperative incapacity, although diminished cognition correlates with impaired capacity for medical decision-making. As the population ages, it is imperative to recognize and manage patients with incapacity to consent for their upcoming surgeries. Studies suggest that physicians often overlook incapacity. In a cohort of 123 older adults presenting to a surgical ward, 111 (90.25%) had consented themselves for surgery, yet 33 (39.7%) had cognitive impairment, and 18 patients (16.2%) were unable to state the reason for admission to the hospital. Often, patients with profound impairment remain able to express a choice, without possessing an indepth understanding of the attendant risks and benefits. Although performing formal capacity assessment on all patients in busy preoperative clinics is infeasible, a brief cognitive screening tool may allow for rapid identification of patients at highest risk of incapacity. The current pilot study had three aims: (1) determine feasibility of cognition and capacity assessment in a perioperative clinic; (2) describe the prevalence of incapacity in older adults presenting for surgery; and (3) examine the relationship between cognitive performance and capacity.


Background: In Prader-Willi syndrome (PWS) obesity and partial growth hormone (GH) deficiency are frequently observed. The risks of cardiovascular diseases and early death are increased. We examined inflammatory markers in adult PWS, before and during 12 months of GH treatment. Method: Twelve PWS adults, median age 23.5 years (17–37) and median BMI 33.8 kg/m2 (21.2–50.4), participated. Serum interleukin-6, tumour necrosis factor α, high sensitive protein C-reactive protein (HCRP), cholesterol, triglycerides, leptin, adiponectin, glucose, insulin, insulin-like growth factor I and body composition were measured at baseline and after 6 and 12 months of GH treatment. Results: Median and range at baseline for interleukin-6 was 9.87 ng/l (1.76–10.72), for tumour necrosis factor α 2.39 ng/l (1.00–3.26) and for HCRP 7.64 mg/l (0.41–41.1) (normal values < 5 ng/l, < 8 ng/l and<5 mg/l, respectively). At baseline correlations between inflammatory markers and age, anthropometry, body composition and the metabolic parameters were non-significant; only positive associations were found between tumour necrosis factor α and body weight (r = 0.617, p = 0.033) and between HCRP and BMI (r = 0.594, p = 0.041). GH treatment non-significantly decreased the levels of the inflammatory markers. Conclusion: In this pilot study, levels of interleukin-6 and HCRP were increased, and GH intervention did not significantly reduce the levels. Chronic inflammation might contribute to the increased cardiovascular morbidity and mortality in PWS.


We present preliminary results of a search for charmless two-body B decays to charged pions and kaons using data collected by the BABAR detector at the Stanford Linear Accelerator Center's PEP-II storage ring. In a sample of 8.8 million produced B-anti-B pairs we measure the branching fractions B(B^0 --> pi^+pi^-) = (9.3^{+2.6}_{-2.3}^{+1.2}_{-1.4}) x 10^{-6} and B(B^0 --> K^+\pi^-) = (12.5^{+3.0}_{-2.6}^{+1.3}_{-1.7}) x 10^{-6}, where the first uncertainty is statistical and the second is systematic. For the decay B^0 --> K^+K^- we find no significant signal and set an upper limit of B(B^0 --> K^+K^-) 6.6 x 10^{-6} at the 90% confidence level.


Monitoring of the process coefficient of variation (CV) with one‐sided CUSUM charts has been considered in the literature. In this short note, we develop a near‐optimal one‐sided CUSUM chart (with an explicit mathematical expression of the reference parameter) for detecting either increases or decreases in the CV of a normally distributed process. It is shown that the run‐length profiles of the existing and proposed one‐sided CUSUM‐CV charts (despite the fact that both charts possess different control‐charting structures) approximately remain the same. However, the proposed one‐sided CUSUM‐CV charts can be easily optimized when detecting a specific upward or downward shift in the in‐control process CV.


KEY MESSAGE(S):
- Medical research will not improve if we simply interpret our results using the clear-cut difference between statistical significance and non-significance
- Medical researchers should be more interested in the size of the observed result than in its statistical significance
- Confidence intervals provide more information than P-values.


The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in late 2019, and has caused a huge number of hospitalizations and deaths worldwide [...]


The paper presents micromechanical formulations of stress dilatancy and their connection to a flow rule in classical elastoplasticity. Dilatancy is inarguably the manifestation of an internal kinematic constraint involving both particle shape and connectivity (texture or fabric) with operative interparticle friction against applied stresses. However, this notion of microstructural dependence is nonexistent in most stress-dilatancy formulations in the literature. We present two different micromechanical approaches that arrive at stress-dilatancy expressions with embedded micromechanical information in the form of a second-order fabric tensor. In connection to stress dilatancy, the underlying nature of the flow rule is next discussed with respect to the dependence of the plastic strain increment vector on the direction of loading (stress increment). It is demonstrated analytically that the flow rule is singular in three-dimensional stress and strain conditions. Finally, the dependencies of dilatancy on fabric are illustrated through various numerical simulations using the micromechanically enriched stress-dilatancy models and a discrete element method.


Smothering of plants when covered by ice sheets. Smothering of alfalfa may cause injury within 1 to 3 weeks, and death within 2 to 6 weeks. Red clover and white clover have tolerance to smothering that is similar to alfalfa, while birdsfoot trefoil and ladino clover are more susceptible to injury. Grasses are more tolerant than legumes to smothering and can withstand injury for up to 10 to 14 weeks. Leaving 6 to 8 inches of vegetative stubble in the fall can help reduce the occurrence of ice sheet formation. Mid-winter dehardening of plants from exposure to extended warm periods. Plants that deharden over winter during warm periods use some of their carbohydrate and nitrogen reserves during this premature regrowth attempt, leaving the plants with a reduced level of cold hardiness and less reserves available for continued survival during the remaining winter and for spring regrowth.


Interest and demand for bacterial pigments is growing due to rising awareness of toxicity of synthetic dyes. This study evaluated on the production of flexirubin-type pigment from Chryseobacterium artocarpi CECT 8497 using liquid pineapple waste in 5-L bioreactor and its application as environmental-friendly ink. Liquid pineapple waste supported bacterial growth and pigment production for C. artocarpi CECT 8497. The ink was successfully formulated with polyvinyl butyral and polyvinyl pyrrolidone giving a smooth texture. The functional groups of formulated ink identified using FTIR were OH, C-C and C-H. Flexirubin ink was stable during the entire storage period of 30 days at temperatures, ranging from 25 to 70°C, pH 1.0 to 11.0 and in the presence and absence of light. This is the first report on ink formulation of flexirubin-type pigment from C. artocarpi CECT 8497 and its potential application on plastic materials.


In the field of vibration control, Direct Acceleration, Velocity and Displacement FeedBack (DAVDFB) is desirable according to the skyhook control theory. We have proposed a first-order differential type seismic displacement sensor which can simultaneously detect absolute acceleration, velocity and displacement signals. Due to low detection sensitivity and narrow bandwidth, however, its control performance is not enough for practical use in industrial scenes. This paper presents a high sensitive method by increasing the number of coil turns, because back electromotive force of a calibration coil is utilized as the velocity signal. Sensitivity calibration and practical control tests are conducted as to ascertain the efficacy using an anti-vibration apparatus.


: The previously reported asymmetric Baeyer–Villiger (BV) oxidation of 3-substituted cyclobutanones promoted by a co-factor flavin derivative was revisited to broaden its scope. The correlation between the stereochemical outcome and the catalyst structure was examined, and only one stereocenter was found to be critical for achieving high stereoselectivity. This observation led to the identification of a new, simpler catalyst with improved selectivity. By positioning a lone pair donor on the substrate, the selectivity was further enhanced to 95% ee using the original catalyst or >99% ee with the new catalyst, among the highest selectivities achieved for the BV reaction using a small-molecule catalyst. This observation supports our hypothesis that the H-bonding network is central to the catalyst. This study demonstrates the power of mechanistic investigation to broaden the scope of catalytic systems and aid in catalyst design. We are currently exploring methods to expand the applicability of this catalyst and demonstrate its use.


ABSTRACT We studied assemblages of soft-walled, single-chambered foraminifera (monothalamids) at eight stations in the area of Zernov's Phyllophora Field (ZPF) on the NW continental shelf of the Black Sea. This work is based on samples collected during Cruise 70 of the RV Professor Vodyanitsky and provides the first analysis of the taxonomic composition of monothalamids from this region. These delicate, poorly known foraminifera were found at all stations in the studied area. They were represented by nine forms that are identified to species or genus level as well as 14 undescribed species, nine of which are found in the Black Sea for the first time. Four species, Psammophaga sp., Vellaria pellucida, Goodayia rostellata and Krymia fusiformis, were most abundant, with Psammophaga sp. being the dominant species overall. Previous studies have suggested a link between members of this genus and eutrophication. There are a number of taxonomic parallels between these ZPF assemblages and those from the Adriatic Sea, e.g. the occurrence of the genera Goodayia, Psammophaga and Vellaria, although it is possible that some other taxa are endemic to the Black Sea.


Ternary compounds of Fe and/or Co with the ThMn12 structure are of interest as possible permanent‐magnet materials. We have studied the electronic and magnetic structures of YCo10V2 using self‐consistent spin‐polarized calculations. The calculations employ the linear‐muffin‐tin‐orbitals method in the local‐density approximation. The Co 3d states dominate the density of states near the Fermi energy with an average exchange splitting of about 1 eV. The calculated magnetization per formula unit for one of the V‐atom configurations (8.11 μB/FU) is in reasonable agreement with the experimental value (7.19 μB/FU). The Co moments for the three sites are quite different (μf = 0.75 μB, μi = 1.39 μB, μj = 0.91 μB). The V and Y atoms develop moments opposite to those of Co due to interatomic exchange interactions with the Co atoms [μ(V) = 0.50 μB, μ(Y) = 0.29 μB].


We establish the complexity of several graph embedding problems: Subgraph Isomorphism, Graph Minor, Induced Subgraph and Induced Minor, when restricted to H-minor free graphs. In each of these problems, we are given a pattern graph P and a host graph G, and want to determine whether P is a subgraph (minor, induced subgraph or induced minor) of G. We show that, for any fixed graph H and epsilon > 0, if P is H-Minor Free and G has treewidth tw, (induced) subgraph can be solved 2^{O(k^{epsilon}*tw+k/log(k))}*n^{O(1)} time and (induced) minor can be solved in 2^{O(k^{epsilon}*tw+tw*log(tw)+k/log(k))}*n^{O(1)} time, where k = |V(P)|.

We also show that this is optimal, in the sense that the existence of an algorithm for one of these problems running in 2^{o(n/log(n))} time would contradict the Exponential Time Hypothesis. This solves an open problem on the complexity of Subgraph Isomorphism for planar graphs.

The key algorithmic insight is that dynamic programming approaches can be sped up by identifying isomorphic connected components in the pattern graph. This technique seems widely applicable, and it appears that there is a relatively unexplored class of problems that share a similar upper and lower bound.


Diabetes mellitus (DM) is the most challenging problem in today's world, it is a complex disease characterized by chronic hyperglycemia, metabolic abnormalities, and long-term macro and micro vascular complications. Type 2 diabetes mellitus (T2DM) accounts for over 80% of cases of DM. HbA1c is a more useful marker to determine mean blood glucose levels over a long time period. This study aims to assess changes in platelet indices and neutrophil / lymphocyte ratio in type 2 diabetes mellitus and their correlation with diabetic control. It is single center study, patients were selected from the outpatients and inpatients of the Endocrinology Department at Al-Zahraa University Hospital, through the period from February 2021 to July 2021. The study was conducted on 40 cases with type 2 diabetes mellitus which divided into two subgroups, group A (n=19) controlled diabetes (HbA1C <7%) and group B (n= 21) patients with uncontrolled diabetes (HbA1C >7%) in parallel with 40 apparently healthy individuals. For all subjects, platelet indices, and neutrophil/ lymphocyte ratio (NLR), prothrombin time (PT), international normalized ratio (INR), and activated partial thromboplastin (PTT) time were investigated. In this study, a significant increase in mean platelet volume (MPV) and PTT were observed in the diabetic group in comparison to the control group. There was a significant increase in WBCs and lymphocyte count between controlled and uncontrolled diabetes. while there was no statistically significant difference of PLTs, MPV, PDW, PCT, NLR, PTT, PT, & INR between controlled and uncontrolled diabetes. Our study revealed that a significant increase in MPV in diabetic patients additionally there is a significant positive correlation between HbA1C and MPV , in addition, changes in coagulation profile (specially PTT) contribute to the thrombotic state in diabetes mellitus.