text:
I am testing MEG7 in test environment and would like to explore its outbound controls. I have a tesst mail server in my test domain but this domain in not routable over internet. So i am thinking of using to send outbound emails to my production email gateway solution - IRONPORT and send inbound mails to my test mail server. I have tried under "email configuration ->sending" tab settings and configured testdomain.com with test mail server IP & then * to set it for rest of the domains with IP of my IRONPORT but this does not work. can we configure MEG7 to achieve this?
Not sure specifically but I'm sure the SE you're working with or support under a temporary grant can do a webex and figure out what config issue you're battling. They do after all have a vested interest in making your POC successful. The "sending email" portion of the email configuration can be confusing. Is it possible your ironport is rejecting the mail since it's coming from an IP that in the past hasn't normally relayed mail through it?
The way I did the POC and tested MEG without disturbing the client's production mail was to take an unused domain of the client and points its MX record to the MEG. For outbound, an Exchange connector was defined to use the MEG as the outbound hop for a specific external email address domain (I used my personal domain... such that from Outlook if any mail was going to be sent to *@mypersonaldomain.com, Exchange would route it out through the MEG).
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text:
Thank you for sharing your thoughts about the tragedy in Connecticut. Here is a sampling of the more than sixty responses I received from family and friends:
"Every American should fly a flag at half mast every day for one month,
and then on the 14th day of every month until the President signs a strong restriction and control of gun ownership."
"Bring back public executions of those cowards and we will see that stuff end quick. Tell those nut cases that if we catch them dead or alive, they will be fed to hungry chimps. Sick of people thinking it is easy to kill and there is no accountability."
"We too are OUTRAGED!!! Thanks for your posting. "
"Did you read George Skeleton's LA Times column this morning? If people "want & must" have guns then … SINGLE SHOT is the way to go."
"As for me…. I say the cat's out of the bag with all the "weapons of war" on the streets of our great country & true gun control may be impossible so… how about ammunition control?"
"It's like Mirabelle's class, exactly her age. She knows nothing yet as they don't have a tv, so hope it's not a rude awakening tomorrow at school. Her teacher e-mailed the parents that she will play it be ear tomorrow, as some kids may be well informed by TV and by parents."
"My grandkids go to school two exits away. My heart was in my throat."
"We did nothing when a President was shot, when a Senator was shot, when a religious leader was shot, when several schools had mass murders, when a congressional rep was shot, when a movie audience was shot, so now there are hopeful people because 5, 6 & 7 year olds were shot. If some controls are not put in place now, then when?"
"I strongly agree with you. No one needs to own a automatic weapon . Look at what happened in the shooter's family. We need to pay more attention to mental health in this country and provide more services."
Your email addresses many of the same feelings we have.. We all need to be involved and stop this insanity that makes this country one of the most violent countries in the world."
"Automatic weapons, which have the ability to kill so efficiently and maximize damage by allowing bullets to explode inside a body's soft tissue, must be eliminated. NOW. "
I looked at the faces of these dear little children and cried. How could this possibly happen? We want to keep our Sophie close to
us and, as you said, give her lots of love. I can't imagine life without her.
"The NRA must do something to demonstrate responsibility to keep certain kinds of weapons from the public."
Email Dr. Linda

subset: commoncrawl


text:
Also known as portable induction cookers, countertop ovens or just countertop cookers, the best countertop burners in 2018 are products that help a lot of homeowners to prepare food quickly and easily without the need of an oven.
However, the best portable electric stove can also be a great idea for your RV, weekend house, college dorm room or anywhere where you cannot fit a regular stove. In cases like those when your cooking is limited, these countertop burners will certainly make most of your needs.
Some of the best benefits of countertop burners in 2018 include energy efficiency as the main ones. According to research, induction is -80% efficient which means that it can let you save while spending and produce less waste heat.
On top of this, the speed, responsiveness and repeatability of these best countertop burners doesn't match any other device in the kitchen – not to mention their functionality for outside-of-the-kitchen situations.
Below, we are listing a few of the best portable electric stoves in 2018 for different needs and purposes:
And below, we are listing each one of these devices in detail with all of their main features explained.
Duxtop's best cooktop countertop burner is a unit that uses 120 volts and 15 amps of electricity. It is lightweight and compact for easy handling and storage.
There is a digital control panel that is built-in with 1 min increments allowing cooking times of up to 170 minutes.
The temperature range goes from 140 degrees to 460 degrees in Fahrenheit as well as 10 power levels from 200 to 1800 Watts. The auto-pan detection shuts the unit automatically after 60 seconds if no cookware is detected, which speaks enough for the enhanced security of the device.
Similar to the first model – yet a lot different – is Secura's best countertop burner in 2018 which can be found at an affordable price for what it offers.
Speaking of which, this unit offers 15 different power levels from 200 to 1800 Watts, 15 temperature-range options from 140 o 460 degree Fahrenheit and a digital control panel.
At the touch of a button, configuring this countertop burner is easy before each cooking session. As a product, it is one of the most lightweight and compact devices for handling and storage – which also makes it one of the best countertop burners are coming at a reasonable price.
If you are a fan of Duxtop and other induction ready cookware, you should know that this product is fully compatible with them as well as any cast aluminium enameled iron and steel, stainless steel with a magnetic bottom or cast iron.
Lightweight, compact and convenient – those are some of the best ways to describe the Cusimax electric counterop burner that is ideal for students, parents on vacation, campers, man cave pancakes, holiday homes or everyday use and entertaining.
Basically, this product is in the list of the best countertop burners in 2018 because of the fact that it works with every type of cookware.
It is also one of the most affordable countertop burners out there that excels when it comes to cooking food including warm sauces, boiling water, making soup, cooking pasta, scrambled eggs, grilled cheese and everything from the basic needs.
On top of it all, the Cusimax countertop cooker is safe (with an automatic shutoff), easy to clean and durable (backed by a 18-month warranty).
This is one of the best countertop burners in 2018 and a best selling product out there. The reasons for that are numerous.
First and foremost is the fact that it packs a digital LCD sensor which makes the functionality a lot easier – and the cooking more fun.
There is also a child safety lock system, a Fast Boil button and a Keep Warm button which are all designed to meet your needs. With 1-minute increments of up to 10 hours and 20 temperature ranges, this countertop burner for cooking will shut itself off after 60 seconds if there is no cookware on it, ensuring maximum safety.
Approved by North American Standards and coming with a 1 year full warranty, the Duxtop countertop burner is another product in the line of great countertop burners designed by the brand. In order to use it, however, you need to have the right kind of cookware which is magnet and induction-ready.
Last but not the least is a model by Rosewill which is also voted as best countertop burner in 2018 by many people. It comes with five pre-programmed settings for different uses such as warm milk, soup, stir fly, fry or hot pot.
Most importantly, this model comes with a polished A-grade crystal plate surface and a LED large screen display with 4 digits. There are also eight temperature settings that range to 450 degrees in Fahrenheit and a safety compliance with features that match most of the best countertop burners in 2018.
All in all, this is a great product to consider and one that looks very elegant and stylish. Most importantly, it is a compact countertop burner that is easy to clean and even easier to store.
A Final Word
In the end, the best portable electric stoves are here to prove that they are the best alternative way to safe and efficient cooking. They require no major initial cost, are easy to clean, save you electricity and time – all while routinely tailoring to your needs, whether you are camping, hiking or staying in your weekend house.


text:
Everyone has a right to justice regardless how long ago the crime
Sarah Champion
The Times
This week Boris Johnson, the former foreign secretary, described investigations into past child sexual abuse as money being "spaffed up the wall". Spaff is a colloquial term for ejaculation.
Johnson's attitude is appalling on many levels and the impact on victims of child abuse has been immediate and very damaging. I know this as survivors contacted me to tell me how deeply upset they were. They told me the comments triggered their guilt at wasting police time, a common anxiety of survivors; fear that they would not be believed; and concern their cases would no longer be acted on.
There should not be a time limit on justice.
Child abusers, and those that have abetted them, must be held to account regardless of when the


text:
What is Hue Walk of Revolution?
Many visitors to Hue wonder what brand new thing to do in the imperial city if you want to search for trace of wars? We are here to recommend you the Hue Walk of Revolution.
This is a very special Hue Walking Tour which compelling excellent pictures of Vietnam revolution during the French and American Wars in Hue.
Mark, a history buff coming from US, was looking for a tour that is totally different from what normally provide by many agents in Hue, found our tour interesting. Here is what he described his experience after taking the walking tour with us!
What Mark Said about his experience?
I recently returned to the United States after a month long intensive history tour of Vietnam and during that time I had the opportunity to meet a variety of tour guides on a number of excellent tours all over the country from Saigon to Dien Bien Phu.
However, one guide, and one experience, stands towering above them all–unique and distinct: the afternoon of November 7th, 2018 that I spent with Le Huyen My as she guided me around Hue for the "Hue Walk of Revolution" tour.
A gentle, scholarly, insightful guide, My took me around her home town and showed me sites relating to the Revolutionary Movement in Vietnam including a monument commemorating a 1909 strike led by Ho Chi Minh located behind the old French HQ in Hue, a monument to the massacre of Monks by President Diem at the site of a long-gone radio station and ultimately to the Citadel where we visited the War Museum.
While viewing the displays, My talked me through a gut-wrenching presentation regarding America's use of defoliants prompting an intense dialogue. Her passionate, emotional, well-informed presentation was so heartfelt, her love of her country so sincere, her enthusiasm for the topic so moving that I was literally reduced to tears.
She provided me not only with information–anyone can do that–but with an intense, cross-cultural bonding moment that eclipsed anything else I experienced in Vietnam. She touched my heart.
My is an incredible, insightful guide–a lovely young woman, wise beyond her years, who is the best at what she does and I consider myself very lucky indeed to not only have taken her tour, but to have spent a few hours in her company–it was like winning the lottery. Those few hours were the best moments of my vacation and were life-changing, moving and will forever remain important to me; she provided a rare moment that I will carry with me for the rest of my life.
I give the highest possible praise to My and recommend any and all visitors to Hue eagerly partake in their brilliantly led tour. I have toured the world, had dozens of tours, and I have never encountered her equal–no one else even comes close. A special experience, led by a remarkable woman that not only brought the Revolution to life–it sparked a revolution within.
Mark point of views when visiting Dong Ba market
During this special walk in Hue, we also take visitors to Dong Ba Market for a local experience. Instead of walking pass the market, we help our clients taste many tropical fruits and sample Hue specialty.
Here are some colorful picture of Hue market under Mark's point of view:
To have all the experience Mark described above, visit Hue Walk of Revolution. Tour runs daily at 8:30 and 14:00. Hue walking duration is 3 hours.
Instead of doing a self-guided walking tour in Hue, why not join us to make it an educational experience in Hue for yourself?
Not only doing a great history tour about Vietnam wars, Bee Bee Travel also offer these great local experience in Hue you should not miss. Check out:


text: > Danny Stroud <dannystroud at msn.com> wrote: > > >So how do you reconcile the increasing number of private facilities? Although > >not exchange points in the truest sense ala MAEs and NAPs, they do carry an > >increasing percentage of cross-network traffic. The number of these types of > >facilities will grow. Maybe our difference here is that I count these and > >others do not. des > > Er. Private exchanges are there only because public exchanges are running > out of gas. They have the same problems with routing as public exchanges do. Actually... many of the private exchanges are there for several other reasons as well. First, it can be convenient to set up a connection with a net you're passing lots of traffic to so you can go direct to them instead of through 7 or 8 odd routers outside your net. (obviously) Second, it can be significantly cheaper to split the costs between the participants and not have to pay a third party for access to the exchange. (heck of a lot easier too..) Third, and going along with the first point, private exchanges can help to more geographically orient your local corner of the network. That way, to get across town, you don't have to go to mae-west, over to denver, and back down to phoenix to travel 6 miles. This also serves to take a little traffic AWAY from the public NAPs and can help reduce congestion and problems there. The principle disadvantage of lots of small exchange points, as far as I see it, is that there may well be potential for A) many more paths to get from A to B, meaning that each router will hold that many more BGP entries and B) possibly a greater potential for route flap. -Wayne


text:
News from the world wide web.
The CIA's communications...
11.11.18, 00:11
News from the Internet, Software, Hardware etc.
Youtube recently deactivated...
23.08.20, 13:10
Newest messages of the game manufacturers.
FIFA 21. Anyone waiting for...
06.10.20, 10:57
News from the P2P world.
EU copyright reform
30.03.19, 19:18
News from the sport world.
Tanya Aldred: we will miss...
11.08.11, 23:49
News about movies, music etc.
Selena Gomez gets death...
19.10.20, 14:50
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text:
Religious Facilities
Rendering of the completed Sagrada Familia
The project has been under construction since 1882.
All images courtesy of RBB Architects
RBB Architects designed the building.
All renderings courtesy Gensler
What once destroyed Notre-Dame will now serve to make it stronger.
Pictured: Klein A45, Catskill Mountains, New York, by Bjarke Ingels Group. This prototype mountainside cabin is entirely customizable for homeowners to purchase, tailor, and have the tiny house built within 4-6 months in any location, for any purpose. Photo: Matthew Carbone
Bjarke Ingels Group's prototype mountainside cabin and Fieldwork's forest pedestrian bridges are...read more
Trinity Church Wall Street, which hasn't been renovated since 1946, will be closed through the Spring of 2020 for extensive upgrades and improvements. Image: Courtesy of Trinity Church
Improvements will include a new lighting and sound system, and a movable altar.
The Sealing Room is where couples are married and sealed to one another in the LDS faith. Interior finishes needed to capture purity, eternity, and love. All photos © Intellectual Reserve, Inc.
Parts of the tabernacle's exterior shell were the only things that survived the blaze.
The plant is the first in a series of upgrades planned for 2017 to adapt one of New York's earlie...read more
Rendering courtesy of Foster + Partners.
The Foster + Partners-designed building will address the shortage of accommodation in Mecca.
Rendering courtesy of InGenious Studio
The Hindu temple will stand 700 feet-tall when completed, easily surpassing the current tallest c...read more
Mypower will install 150 solar panels on the roof, making it the oldest cathedral in the UK, and...read more
Pixabay Public Domain
Gensler, Leo A Daly, Brasfield & Gorrie, Layton Construction, and AECOM top Building Design+C...read more
Ark Encounter. Photo and video courtesy Ark Encounter.
Ark Encounter, the largest timber-framed structure in the world, opened in Kentucky.
The Philadelphia Episcopal Cathedral, with the 3737 Chestnut building in the background. Courtesy BLT Architects. Click here to enlarge.
The Philadelphia Episcopal Cathedral capitalizes on hot property to help fund much needed upgrade...read more
A 50-foot x 90-foot metal building system from Star Buildings allowed the church to build its bas...read more
Rendering courtesy Adrian Smith + Gordon Gill Architecture. Click here to enlarge.
The ellipse-shaped building has plenty of gathering spots and outdoor views.
The recently completed St. Nicholas the Wonderworker in Plovdiv, Bulgaria, includes a 12-ton metal dome, the first of its kind to be included in new construction of a basilica in that country. Image: HMC Construction
The church is 2½ times larger than the basilica in Ukraine it references.
Perot Museum of Nature and Science. Photo: Joe Mabel via Wikimedia Commons
Morphosis' Perot Museum and Studio Gang's WMS Boathouse are among the projects to win AIA's highe...read more
This AIA CES Discovery course discusses the six elements of an EIFS wall assembly; common EIFS fa...read more
Six new towers to be added will make the cathedral Europe's tallest religious building.
Six new towers to be added will make the cathedral Europe's tallest religious building.
The 16,000-sf temple, in the wooded suburbs north of Columbus, OH, utilized a Star Building System. Although it does not look it, it is a single-slope roof structure.
The beliefs of the congregation required specific compass-orientations for certain rooms
Images courtesy Murphy Burnham & Buttrick Architects
The three-year reconstruction project included more than 30,000 preservations and repairs.
A Boston developer is proposing to build an eight-story residential building along the existing wall of a former 19th-Century church, which has been vacant for five years. Rendering courtesy Finegold Alexander Architects
Former churches, many of which are sitting on prime urban real estate, are being converted into l...read more
People would be able to enter the restaurant from Fifth + Columbia, a $400 million, 43-story tower that Daniels started building in June 2014 and is scheduled to complete in 2017. Rendering: ZGF Architects
A Seattle-based real estate developer plans to convert a historic downtown building, which for mo...read more
The Vanderbilt Medical Center at One Hundred Oaks Mall transformed a former 1960s-era indoor shopping mall in Nashville, Tenn., into a mixed-use medical office center for Vanderbilt University. Photo courtesy Vanderbilt University
Approximately one-third of the country's 1,200 enclosed malls are dead or dying. The good news is...read more
The Illinois Institute of Technology's Main Building is among the city buildings at the highest risk of being lost to demolition or decay, according to the group Preservation Chicago. All photos provided by Ward Miller of Preservation Chicago
Preservation Chicago released its annual list of historic buildings that are at risk of being dem...read more
Image via Wikipedia
Architect Jordi Fauli has taken over responsibilities for finishing Antoni Gaudi's masterpiece. F...read more
Metal church in Spitak, Armenia (then part of the U.S.S.R), built after the earthquake in 1988. Photo courtesy of Mcsochi/Wikimedia Commons.
Affordability and speed of building are important factors.
Photo credit: Mikkel Frost
Copenhagen, Berlin, and Rotterdam are the cities where most of the shortlisted works have been bu...read more
Nearly 100 years after Antoni Gaudí's death, Chile will begin constructing a chapel using his des...read more
Calatrava reveals that he wanted to retain the "tiny home" feel of the original church building t...read more


text:
We are proud to present an updated version of video conferencing server for private corporate networks — TrueConf Server 4.1.3.
In addition to the updated TrueConf Client 6.4.1 for Windows, this version also includes some minor changes to improve the reliability
and stability of the software.
Fixes in TrueConf Server 4.1.3 on Server Side:
- Fixed a bug when main domain controller could be defined wrong if there are multiple domain controllers in the network and the LDAP mode in
TrueConf Server is on.
- Several bugs with SIP devices integration were fixed due to improved SIP protocol support.
TrueConf Client 6.4.1 Server Client Application Update:
- Added a built-in screen capture driver installation for Windows 8/8.1, that was excluded since version 6.4.0.
- Fixed a problem with video freezing in HD mode during calls on PCs with certain versions of Intel HD Graphics integrated
graphic processor.
- Changed 'Alt + W' shortcut combination for closing chat tabs in some keyboard layouts, including Polish.
- Fixed problems when establishing a call using Transparent Proxy connection to TrueConf Server.
- Noises fixed during group video conferencing when CPU usage is high.
- Fixed a bug with "Microphone Off" icon, that used to be displayed only once per user during a conference.
You can download the latest version of the software from our website. Feel free to contact us if you have any questions!


text:
A witty design, the each piece in the Twist Coaster Set stacks together. As they're stacked, the rotation builds so that the column appears to twist upward. Sold as a set of six.
- Made of Acacia Wood and Nambé Alloy
- Stacked: 4.25" L x 4.25" W x 3.5" H
- Indv: 4.25" L x 4.25" W x 1/2" H
- Hand wash; dry immediately
- Designed by Lou Henry
- DESIGNER: Lou Henry
- DECOR STYLE: Mid-Century Modern
- OVEN SAFE: no
- DISHWASHER SAFE: no
- ONLINE ENGRAVING: no
- GIFT TYPE: For Him
- LIMITED EDITION: no
- MATERIAL TYPE: Wood
- ONLINE EXCLUSIVE: no
About The Designer:
Lou is the creative force behind A2, Inc., a product development firm based in New York City.
A2 has been designing products to meet the demands of everyday living for the last 25 years. They have won numerous design awards & recognitions, including IDEA Gold awards, Good Design awards, a Top Ten IF award in Germany, and Time Magazine's Top Ten Designs. Lou's work can be seen in the permanent collections of a number of museums such as The Chicago Athenaeum and MOMA in New York. A2 is named on hundreds of utility and design patents.
Having earned a degree in industrial design from Carnegie Mellon University, Lou has since been busy putting his personal touch on an endless stream of products and developing entire brands from the ground up. His work is characterized by unique solutions and a relentless pursuit of simplicity


text:
Chiltern landscape oil painting 'A break in the clouds'
I made this painting on Chorleywood common during the last couple of hours of sunlight. Chorleywood common is on the edge of the Chiltern landscape and is one of my favourite locations for oil painting. I was hoping that as the sun dipped nearer the horizon it would drop below the cloud cover on this fairly overcast day, and I was lucky. The painting was made in-situ with artist quality oil paint on a hand made canvas panel and is available to purchase at £225, which includes free UK delivery. The artwork is initialed on the front and signed on the back and also has a signed certificate of authenticity. 'A break in the clouds' is sold unframed but framing options are available if required. Please drop me a line at firstname.lastname@example.com for details. The image copyright is retained by the artist.
Back to Landscape Painting Gallery


text: It doesn't make any sense and it doesn't really do anything useful, but I've been playing around with Word Perhect for the past half hour. I can't do it justice by trying to explain it here except to say that it's a hilarious online word processor that doesn't actually do anything. It's either the dumbest thing ever or a stroke of genius. Maybe a bit of both. Anyway, give it a whirl.


text:
Top Miami Motorcycle Accident Lawyers
Payer & Associates
Payer and Associates is a personal injury law firm in Miami, Florida. They hand cases relating to car accidents, workers compensation, motorcycle accidents and other personal injuries. They work vigorously to ensure that you get the just you deserve. If you have been injured, give our Miami injury attorneys a call today.
Address : 2210 NW 4th Terrace, Miami FL, 33125
Phone : (305) 854-4442
Law Offices of Mark A. Kaire
At The Law Offices of Mark A. Kaire, you can reach a personal injury attorney at any time: 24 hours a day, 7 days a week. We handle cases involving: Motor vehicle accidents, Medical malpractice, Workplace accidents and construction accidents, or Dangerous or poorly maintained property.
Address : 80 SW 8th Street Suite 1710, Miami, FL 33130-3038
Phone : (866) 769-0123
Gerson & Schwartz
Our Miami, Florida personal injury attorneys handle cases in a number of different practice areas including: Car, Motorcycle, and Auto Accidents, Trucking Accidents, Premises Liability, Slip and Falls, Security Negligence, Wrongful Death, Nursing Home Abuse and Neglect, Medical Malpractice, Vehicle Rollovers and Tire Defects, and more.
Address : 1980 Coral Way, Miami, FL 33145
Phone : (305) 606-8140
Friedin Dobrinsky
We help personal injury victims of car and truck accidents, medical malpractice, and premises liability. Our lawyers also serve consumers throughout Florida, including Miami, Ft. Lauderdale and Ft. Myers, who are victims of consumer fraud or unfair and deceptive business practice.
Address : 2 S. Biscayne Boulevard Suite 3100, Miami, FL 33131
Phone : (305) 371-3666
Bernstein & Maryanoff
Bernstein & Maryanoff is a well-established personal injury law firm with offices in Miami and across Florida. With a staff of approximately 40 people, including six lawyers and 34 support personnel, we have the legal resources to handle catastrophic personal injury and wrongful death cases.
Address : 15055 SW 122 Avenue, Miami, FL 33186
Phone : (305) 253-1000
Needle & Ellenberg, P.A.
Our experienced team of lawyers is available to handle brain and spinal cord injury cases and all other varieties of catastrophic injury cases related to motor vehicle accidents, such as: Car Accidents, Truck Accidents, Motorcycle Accidents, Aviation Accidents, Railroad Accidents, and Boating Accidents.
Address : 1401 Brickell Ave. Suite 900, Miami, FL 33131
Phone : (305) 530-0000


text:
Free Return on all orders. . shipments will be delayed.
Free Return on all orders. . shipments will be delayed.
Turtleneck women's sweater crafted from plain knitted cashmere. The mock turtleneck features a dense micro-ribbed pattern. Its precious and exclusive yarn turns this garment into the luxury version of an essential knitwear item.
This sweater is made with the best cashmere fibres, accurately selected by Lanificio Colombo in the Hircus goats breeding farms of Inner Mongolia. Lanificio Colombo is one of the few companies in the world able to guarantee a complete supervision of the entire production chain, from the purchase of the fibres through the manufacturing process in its plant among the green Alpine valleys until the finished garment.
How to use
A "must-have", essential to any women's wardrobe. The exclusive fabric, extremely soft and enveloping, is a valuable plus.
Composition: 100% cashmere
Colour: black
Classic fit
Micro-ribbed mock turtleneck
Made in Italy ***
The model in the picture is 180 cm and wears a size 42.


text:
This 9 piece hex key set from Wera features 9 individual hex keys, each at different lengths and thicknesses, enabling the set to cater for a multitude of tasks in a domestic or commercial environment.
Features and Benefits Ball ends improve access to restricted areas The keys are precision formed to give an exact dimensional tolerance, to give a precise fit The L shape and long reach makes it easy to reach deeply in-set bolts Make use of both ends of the hex key 20% more torque transfer High corrosion protection Each key is engraved, making key location easy Secure, wear resistant clip keeps all keys secure when not in useWhat size are the Hex Keys?The contents of the hex key set include: 1 x 1.5x90, 1 x 2.0x100, 1 x 2.5x112, 1 x 3.0x126, 1 x 4.0x140, 1 x 5.0x160, 1 x 6.0x180, 1 x 8.0x200 and 1 x 10.0x219Did you know?A Hex Key is commonly referred to as an Allen Key, this is because Allen was the original manufacturer of the Hex key.Also, a hex key can be reconditioned using an electrical grinder, or similar type of equipment. Through removing the worn out part, the hex key has the capability of functioning like its brand new again – Although this type of maintenance should be minimal if the hex key is cared for and kept in a good condition.
From Wera comes this high-quality L-shaped hex key set for hexagonal socket screws, finished with a chrome plating for high corrosion protection and long service life. Supplied in a practical wear-resistant clip fastener that ensures secure storage and simple key removal, your tools will be to hand when you need them most.
A hex key is most commonly known as an Allen key or Allen wrench and is mostly used as a small hand tool to drive bolts or screws with a 6-sided hexagonal or Allen socket.
They are an incredibly versatile tool that can be used across a variety of applications. Hex Keys & Bit Sets are used by Plumbers, Electricians, Mechanics and Electronic Engineers.
Is this a ball end hex key?
Yes, this set of hex keys has a ball tip on one end to assist with angled, around-the-corner screwdriving jobs.
Are Allen keys and hex keys the same?
Yes, they are the same. Allen is a registered trademark/brand that is particularly popular in the US and has become like a synonym for hex keys.
Are the hex keys imperial or metric?
This set of hex keys is metric.
What is in this hex key set?
This hex key set contains:
|Imperial or Metric
|Number of Pieces
|Hex Key Size
|Short or Long Arm
|Hex Key Type
|Ball End


text:
Ward gets easy win over Barrera in light heavyweight debut
OAKLAND, Calif. (AP) — Andre Ward unanimously outpointed Sullivan Barrera in his light heavyweight debut Saturday night, setting the stage for a potential title fight against unified champion Sergey Kovalev.
Ending a nine-month layoff while fighting for just the fourth time in four years, Ward (29-0) knocked down Barrera in the second round with a sharp left. The 34-year-old Cuban bounced up quickly before Ward landed another pair of stinging lefts to the head.
About the only thing to go wrong for the Oakland fighter came late in the eighth when referee Raul Caiz deducted a point from Ward for a low blow that sent Barrera (17-1) down to one knee. Ward also drew a warning in the 10th for an accidental head butt.
All three judges had Ward winning easily. The scores were 117-109, 119-109 and 117-108.
The win paves the way for Ward to fight Kovalev, the Russian slugger who has defended his title three times since beating Bernard Hopkins in a unification match in 2014. While talks between both camps have been ongoing, things are expected to heat up now.
Fighting in front of his hometown crowd, Ward was the quicker fighter most of the night and used his jab to score often, mixing it with a powerful left hook that landed to the head frequently. He also ducked away from most of Barrera's punches and at one point in the sixth smiled after Barrera swung and missed twice.
Ward continued to score with his big left hand throughout the bout and drew loud cheers from an intimate but raucous crowd at Oracle Arena.
Barrera, the IBF's No. 1 contender going into the night, landed his own jab with some success but couldn't put much together and lost for the first time in his career.
NBA MVP Stephen Curry of the Golden State Warriors watched the fight from ringside not far from Oakland Raiders owner Mark Davis. Former NFL running back Marshawn Lynn and former world boxing champions Roy Jones Jr. and Shane Mosley also were on hand.
Kovalev, who called Ward a "gentleman, a nice man," before the fight, was in the crowd as well.
The 32-year-old Russian predicted an easy Ward win before the fight and said a matchup against the former Olympic gold medalist would be the biggest challenge of his career.
"November is a great time," Kovalev said. "Let's do it, me and him, a done deal."
Kovalev and Ward could each have another warm-up before their eventual bout which is expected to be on pay-per-view.
Had Barrera won, the picture would have been a lot more uncertain.
Although the stakes were billed as being for the expected title shot with Kovalev, Ward had a stipulation added to the contract guaranteeing him a rematch with Barrera first.
It didn't happen, setting the stage for what many are already billing as a potential fight of the year even though no deal has been finalized.
"It's going to be the opposite from Mayweather-Pacquiao in every way," said Main Events promoter Kathy Duva, whose stable includes Kovalev.
In the semi-main event, Joseph Diaz Jr. remained unbeaten with a 10-round unanimous decision over Jayson Velez.


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1. Vintage photobooths have been around long before the craze took hold. Starting in Echuca, they've now grown their business to most Australian capitals. The booths are Art Deco inspired design with lush fittings and plenty of props to have guests cramming themselves in.2. Self Preservation showcases the talents of a selection of independent jewellery
Adam and ChantelleFrom the moment I met Adam, I knew there was something special about him, he was funny, talkative and had a spark that I decided I never wanted to be without. We met at work in 2007 and 10 months later moved to London to pursue our mutual dream of living and working
Callista features bold fat lettering in the cursive style. Callista is from the Greek for 'most beautiful' and it certainly is that – easy to read, bold and yet with just enough curly bits to add charm. This font doesn't need much – perhaps just a simple border to set it off, and your invitations
Thi and JamesI did a double take as I was working through the images of Thi and James' wedding. Surely it must be in Bali? Or a tropical Island? Nope, this beautiful wedding took place on Queensland's Sunshine Coast, but could easily be mistaken for a far flung destination with it's relaxed beauty.Thi tells the
When it comes to the newest in store collections from Australian designers, Spring has well and truly sprung and with it, brought some beautiful options for Spring bridesmaids! Floral patterns, rich raspberry reds and soft, feminine pinks. Such a beautiful look for garden, spring time weddings!1. Alannah Hill "My Love Shock! Frock" Gown 2. Review
The story of Zac and I started at uni, in the library, where he walked past me casually and caught my eye. I knew from that moment that I had to speak to him! I started to bombard my friend with questions about whether she knew him and it turned out she did. She introduced
We were delighted to be introduced recently to the Geo F Trumper range for men by online retailer Men's Biz and I asked Papa Polka and Mr Polka to test out the products for me. Let's establish straight off the bat that I had to write the review because they both claimed to be horrid
Good morning! Did you have a lovely weekend? It's been a big few weeks of developments at Polka Dotty land and I'm looking forward to getting this week underway!Before we get started into a jam packed week of inspiration, let's take a peek at Ms Polka Dot's DirectoryPlease take a moment and check out our
1. Charm bracelet from MichelesCottage 2. Crystal and pearl bracelet from PixieDustFineries 3. Swarovski white pearl bracelet from MelJoyCreations 4. Bracelet from PearlyJaneBridal 5. Peapod bracelet from JenniferMoonJewelry 6. Bracelet from myfirstjewellery
I have been blown away by today's guest's success I still remember her first gowns and I remember the gown that I seem to see every single time I log onto Pinterest! Welcoming to Polka Dot Wisdom today, Melbourne designer Anna Campbell!Please tell us a little about yourself – is there someone special who was/is
As some of you may know I am currently in Greece (part for holiday and part for family obligations) so I guess a Mediterranean theme was bound to pop up! What surprised me as I was putting this together was that I wasn't drawn to the bright blues and yellows of the Greek Mediterranean but
Photo by Chanelle Leslie
Kendall & MarkI love today's engagement shoot. It's so wintery, cosy and warm and pays homage to the couple – Kendall and Mark's, story. Kendall and Mark have been together a long time and have a little boy Ned and twins yet to come! The wedding was moved (due to the impending arrival) so together
I have to make a confession before we get into today's inspiration board. I am not a neon girl. I am not one to own a yellow neon satchel, or don a pair of orange neon flats. To be honest I feel a bit silly, I'm not quite cool enough! But there is no denying
Photo from If I (Your Photographer) Was The Boss Of The World And Your Wedding by Studio SomethingWhat a week it has been dear Dotties, we are this close to launching a project I have been working on for the past six months (hooray!) and I've been sitting here getting more and more wistful as


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Great news for me this week. I've been able to confirm my trip to Guatemala in January. This time the trip isn't for cup of excellence but for me to go and visit some of the farms we have bought from and plan to buy from next year. Also it's a chance for me to expand my coffee knowledge with trips to farms and to mills to see from seed to cup. Of particular excitement to me is the chance to go and see coffee farms during harvest time.
I hope to bring back lots of pictures, lots of storeys and lots of great coffee. Got to say thank you to Mrs Has Bean who is letting me go off on this expedition, who will be holding the fort while I'm away, she puts up with a lot bless her.
There will be more about this as it gets closer, in fact you may have to tell me to shut up


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Innovations and breakthroughs in the world of modern technology are continuous, and there isn't a day going by that some genius inventor or conceptualist is storming up ideas on what new discoveries are to be realized. For the most part, today's society finds it easy to adapt to these changes and improvements, but there are some folks out there who aren't so keen on learning new things. In fact, they're so used to keeping things simple that the stuff you see in store shelves these days prove to be such undecipherable devices and gadgets that will just confuse them even further. Case and point the following pictures…
We get the importance of hardware maintenance. We are PC users ourselves, and we'd like to make sure that all the internal parts are fully functional. Yet, what's a little dusting off anyway? Not effective enough for you, bro? You just had to wash it down? Good luck turning it on again.
Yeah, that's how you read the logo. There is a company called DY... In that thing you call a mind, mom. Wait, what's that? I said to turn the laptop upside down? Oh, HP Laptop, that's what it's called? Yes, that's what it's called.
Again with the lack of appropriate knowledge on the use of modern tech. Yes, we understand that you're still exploring stuff around your mobile device. Yes, we understand that you can't remember all the shortcuts. Yes, we are totally laughing at your expense right now. Talk about old school, this surely defines it.
Gotta love parents. For all their knowledge of the harsh realities of this world we're living in, they sure can be somewhat amusing when it comes to modern technology. Then again, we can just be smart asses about their accidental naivety on all things digital. Yes, we totally agree with the child here. We'd be driving several Fords too if we owned Google.
We can only imagine the look on his face if his mom ever moved the icons on the tray by accident. We just wonder how many photos of himself he can take to get the message across. That'll be a whole lot of unnecessary storage used up on the computer. The next thing you know, your mom's going to complain that everything's so slow in working. Oh well, time to delete some stuff then.


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Dumpster Rental in Peoria City, IL
The Best Rolloff Dumpster Rental Prices in Peoria City IL For Construction or Residential Dumpsters
- What size do you need?
- How much will it cost?
- Do you need a permit?
- What about recycling?
A good plan is the key to the success of any endeavor. The beauty of the whole process is that you just throw the debris and junk into the container, and call us once you are finished. We might be sanctioned for proceeding without legal authority. There's also the issue of permits that you need to secure from your local city office if you plan to rent a dumpster, and you have no idea about the timeline of approval.
Dumpsters come in all types and sizes. It's important that you know the carrying weight beforehand before having one roll into your property in the Peoria City area. However, you have to settle on the right size for the dumpster to be rolled into your property. The cost will hinge upon how large the container is, as well as the type of container you need.
To Help answer any roll off rental questions you may have we've put together this Guide to Renting a Dumpster, we hope you find if helpful:
- Choosing The Best Dumpster Size For Your Project
- Understanding Dumpster Rental Prices in Peoria City
- When Do You Need a Dumpster Permit & When Don't You
What Size Dumpster Is Right For My Project?
10 Yard Dumpster
20 Yard Dumpster
30 Yard Dumpster
40 Yard Dumpster
It would merit a fine on our end. It takes a dumpster expert to know the right amount of junk to go inside a dumpster. Well, you probably can if the volume of your waste does not exceed the container's capacity. Otherwise, you must know that overfilling your dumpster is not wise. In fact, you may have to pay an additional fee for that, or worse, the driver may leave you with all the junk that can no longer fit in the container. You should strive to find the one that will fit your height. You need to know exactly which type of dumpster meets all your needs, so it's a good idea to research about it and find as much information as you can until you figure out which one to rent. Afterwards, the disposed of trash is recycled in an environmentally friendly manner.
The most common sizes include the 10, 20, 30, and 40-yard dumpster containers. If you are dealing with a simple general cleaning and getting rid of waste that take up too much space in your yard, or a major renovation project that will accumulate unimaginable waste, we can help you. No matter what your project is, debris will always be present. Pick the correct size for your project to avoid problems along the way. There are also several sizes in between like the 15-cubic yard, 20-cubic yard and the 30-cubic yard.
To discuss your needs, please give us a call at 309-319-7119. The type of dumpster you need also significantly contributes to the final price. The entire rental process is made easy by using a roll off rental company that can help you decide on the proper size and style of dumpster container that can best suite your needs. These are but general reference points, just to give you an idea on what is the appropriate dumpster size for a particular project.
What Our Customers Have to Say
What Is the Price of Dumpster Rentals?
We cannot give you the exact price, though, because there are factors that come into play. We cannot provide an estimate without first talking to you and finding out some basic information. While we can't really give specific numbers without first getting the basic information coming from our potential clients, let's just say that you will spend anywhere between $100 and over $1,000. Here are the various types you must be aware of:
- construction job sites
- remodeling projects
- roofing projects
- landscaping jobs
- home cleanouts
- just about any kind of debris removal
Here are some examples of dumpster content:
- roofing & shingles
- dirt & yard waste
- construction debris
- concrete
- household junk
Talk to us at 309-319-7119 so you will know further the prohibited items in the landfill. The costs are higher when you are getting rid of materials that are hazardous or prohibited. For one, liquid and hazardous wastes like mercury, lead, paint, thinners, and automotive fluids are banned.
Legal Authority to Use a Dumpster Rental Service
We recommend your forward planning if you're wondering whether or not you need permits for your dumpster. If you have made up your mind about the type of dumpster you want. What then? If you need to secure a permit, then do so by all means.
Obtaining a permit is tantamount to respecting your neighbors and the local Peoria City regulations. Not obtaining one may subject you to violations resulting in additional fines, which you surely do not want right now. In addition, don't forget to check the rules for your HOA or rental community if one of them is applicable. In this case, you will be required to obtain a permit.
Call our number at 309-319-7119 if you want more clarification. We hope that we answered your questionsregarding rentinga roll-off container.


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Second-generation genome sequencing and alignment of the resulting reads to in silico genomes containing antimicrobial resistance and virulence factor genes were used to screen for undesirable genes in 28 strains which could be used in human nutrition. No virulence factor genes were detected, while several isolates contained antimicrobial resistance genes.
A large variety of bacteria are intentionally added to the food supply. These include starter cultures for production of fermented foods and probiotics in food and dietary supplements. Since these bacteria are typically viable when consumed, considerable characterization is required to ensure the absence of undesirable properties (11, 13).
European Food Safety Authority (EFSA) guidelines specify the presence of transmissible antimicrobial resistance genes and virulence factors as undesirable (1, 3). More than 375 types of antimicrobial resistance genes, encoding resistance to nearly 250 antimicrobials, are described in the Antibiotic Resistance Genes Database (ARDB) (7). The Virulence Factor Database (VFDB) (15) contains the sequences of 2,353 genes, representing 408 virulence factors and 24 pathogenicity islands.
Construction of in silico genomes.
Antimicrobial resistance gene sequences were downloaded from GenBank and imported into Genomic Workbench 3 (CLC bio, Aarhus, Denmark) to create an in silico genome containing >250 concatenated gene sequences (see Table S1 in the supplemental material). The primary sources were ARDB (7) and an online overview of tetracycline and macrolide-lincosamide-streptogramin B (MLS) resistance genes (http://faculty.washington.edu/marilynr/), supplemented with our knowledge of antibiotic resistance genes in species relevant to food, previously described genes in Gram-positive bacteria, and EFSA recommendations regarding particularly undesirable antimicrobial resistances (2).
All 2,353 DNA sequences from VFDB (15) were downloaded into Excel, imported into Genomic Workbench, and converted into an artificial genome of virulence factors (see Table S2 in the supplemental material).
RNA polymerase B subunit (rpoB) genes were included as positive controls. The nucleotide sequences of both in silico genomes are included in the supplemental material.
Bacterial strains are listed in Table 1; the prefix CHCC designates strains from the Chr. Hansen Culture Collection isolated from food and other natural sources. Bifidobacterium animalis subsp. lactis IPLAIC4 has been described previously (5). Taxonomic designations are based on 16S rRNA gene sequences.
Preparation of genomic DNA and sequencing.
Bacteria were cultured overnight in M17 (Oxoid, Cambridge, United Kingdom) or MRS broth (Difco, BD, Franklin Lakes, NJ) and harvested by centrifugation (5 min at 4,000 × g). Total genomic DNA was purified using the DNeasy blood and tissue kit (Qiagen Inc., Valencia, CA) according to the manufacturer's instructions for Gram-positive bacteria, with one modification: purified DNA was eluted in water and concentrated to 200 ng/μl by vacuum drying. DNA was sequenced using Illumina GSII 38-bp single reads or 38-bp paired-end reads by Source BioScience (Nottingham, United Kingdom). Results were 2 to 15 million raw sequence reads in Fastq format, corresponding to 20- to 300-fold genome coverage. The sequences of Escherichia coli strains MG1655 and TW03542 were from the NCBI Sequence Read Archive (14).
Genome assembly and analysis.
The in silico genomes were used as scaffolds to assemble the 38-bp sequence reads into contiguous sequences. Assembly occurs only when there is significant similarity, and a gene is detected only when many overlapping fragments can be assembled. When a gene is present, it is possible to assemble the complete gene with a depth of coverage comparable to that of rpoB from the same species. Variations in the efficiency of DNA sequencing and genome size result in different depths of coverage. Results are considered reliable if the depth of coverage is >20. rpoB is chromosomal in all species studied and was used to determine the relative copy number for any gene detected. Partial genes and chimeric genes can also be identified. When a gene is absent, no assembly to that part of the in silico genome occurs.
Sequence assembly was done as "Reference assembly" using Genomic Workbench 3, with up to 4 mismatches allowed per 38 bp. The specific parameters used are as follows: fast, ungapped reference assembly; mismatch cost, 2; and limit, 8. In the case of paired-end data, the parameters were as follows: minimum read distance, 180 bp, and maximum read distance, 600 bp.
Detection of antimicrobial resistance genes and virulence factors.
Figure 1 indicates the detection of tet(W) in B. animalis subsp. lactis IPLAIC4 and tet(S) in Lactococcus lactis CHCC6005. tet(S) in CHCC6005 has a coverage 12-fold higher than the corresponding rpoB gene and is inferred to be plasmid borne. All other antimicrobial resistance genes detected (Table 1) have the same coverage as the relevant rpoB gene and are inferred to be chromosomal.
Antimicrobial sensitivity testing was done using Etest strips (AB Biodisk, Solna, Sweden) as described previously (6). B. animalis subsp. lactis strains CHCC13471, ATCC 27536, and IPLAIC4 show low-level resistance to tetracycline, which has a MIC of 16 μg/ml for these strains. L. lactis CHCC6005 shows high-level resistance to tetracycline (MIC > 256 μg/ml). Gueimonde et al. (5) showed by molecular techniques that IPLAIC4 indeed contains tet(W). The presence of tet(S) on a plasmid in CHCC6005 was confirmed by Southern hybridization and DNA sequencing (12). None of the MICs of the antimicrobials tested (ampicillin, streptomycin, kanamycin, gentamicin, chloramphenicol, tetracycline, erythromycin, quinupristin-dalfopristin, vancomycin, trimethoprim, ciprofloxacin, linezolid, and rifampin) for the other strains were above the breakpoints described previously for the various species (4, 6, 10).
Only the two E. coli strains contain any of the virulence factor genes (Table 1).
Advantages of the screening method.
In contrast to phenotypic methods, this screening method is independent of growth conditions. Detection of newly discovered genes does not require laboratory work; a simple in silico analysis is sufficient. False-positive results will not occur, as a complete gene cannot be assembled, at a depth of coverage similar to that for rpoB, if the gene is absent from the strain. False-negative results are also unlikely, especially for well-known genes, of which many variants are included in the in silico genome. This type of analysis can be used for the detection of any gene of interest.
Screening is done without gap filling, generation of a complete circular genome sequence, or annotation. While some sequences may be missing, it is unlikely that, with a depth of coverage of >20, any gene will be completely absent from the sequence data. Assembly of the sequence reads for Lactobacillus johnsonii CHCC5774 to the published genome sequence of Lactobacillus johnsonii NCC 533 (9) reveals many single-nucleotide differences but only four small deletions (<200 bp). Thus, use of raw sequencing reads is unlikely to lead to undesirable genes escaping detection.
Safety considerations.
We have tested 28 strains for the presence of >250 antimicrobial resistance genes and >400 toxin and virulence factor genes. L. lactis CHCC6005 carries the tet(S) gene on a medium-copy-number plasmid, of which this strain should be cured before use. All three B. animalis subsp. lactis strains contain tet(W). This determinant is widespread in B. animalis (5); no naturally occurring B. animalis subsp. lactis strain lacking tet(W) has been described. Transfer of tet(W) from B. animalis subsp. lactis to other bacteria has never been demonstrated (5, 8); thus, tet(W) is not considered to be transmissible.
We show here that second-generation genome sequencing can be used to screen strains for unwanted genetic content and provide a conceptual framework for querying any collection of genes assembled into an in silico genome. This screening supports, but does not replace, normal safety assessment of new strains.
Masoumeh Taremi, Jannie Schnabl, and Karin Schlichter are thanked for technical assistance.
- Received 22 October 2010.
- Accepted 8 February 2011.
- Accepted manuscript posted online 18 February 2011.
↵† Supplemental material for this article may be found at http://dx.doi.org/10.1128/AEM.02493-10.
- Copyright © 2011, American Society for Microbiology


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February 13, 2019
The availability of metals is conditional for the development of innovation-critical technologies needed in the transition to a sustainable society. However, the extraction and processing of such metals need to be sustainable. On challenge with this transition is to ensure that investors, consumers and producers have information and knowledge about the sustainable burden of metals used in production. Today, the information available does not include, for example, details of the environmental impact of certain metals or whether the employment of child labour are used in the mining and refining of metals.


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Either you are up for buying the new car tires or wondering whether you should have a new set of tires or not. In any of these two cases, there are a few important questions that you must ask yourself before heading to the dealership. So let's dive in:
What type of Tire Should I Buy?
When it comes to type, there're 5 most common options you can consider. For example Summer Tires, winter tires, all-season tires, truck tires and performance tires. The type of tires you are supposed to choose entirely depends upon the area you live and driving needs. If you live in an area that receives snow and wintery season almost 1/3rd or 2/3rd of the year, then winter tires are the best choice for you to get along with.
On the other side, all-season tires would be the best fit if you live in an area that receives all four seasons. Besides weather, also consider points like braking, handling, driving noise and rolling resistance etc.
How much tread do I have left?
Apart from the tire damage situation or overall age of the tire, it's mostly about how much tread the current tires have when it comes to replacing the car tires. If you are wondering about your tire's tread depth, here's the best way out. Just try out the penny test. Just grab a penny and place it in the tread grooves. If most of the coin is out, the tread life is at its end. Consequently, it's time for you to consider buying the new car tires.
Should I buy in pairs or all four at once?
Usually, experts always recommend that you should buy car tires in the sets of four. But still, it depends totally on the situation of your vehicle. Keep in mind that all four tires should have a similar tread pattern and type. When you buy all four, you can easily figure out the wearing time of your car tire. Since they all were bought at the same time, they are more likely to have the same amount of wear within the same time span.
But some of you may not be financially sound enough to afford all four at once. Therefore, you can purchase only 2 at a time. When you buy the new tires in the set of 2, make sure that the new tires will be installed on the rear axle.
What are my dimensions and vehicle type?
Always pick the correct size whenever you plan to buy car tyres online Dubai. Do you know the exact size of your car tire? If no, don't worry about it. You can easily find it in the owner's manual. In case you can't find that for whatever reason, you'll find it written on the sidewall of your current car tires. Just take your car to the dealership, they will read it from your car and give you the best and a suitable car tire.
Important Note: Never Mix & Match the different sizes and tire types.
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Laura and I are so excited to be able to open as from Monday 13th July and looking forward to seeing you all.
We still are following all government and professional guidelines, therefore limited patients per clinic days and a reduced treatment list for the time being.
Please see our latest newsletter for important information on the measure and changes that have taken place:
The Latest: On the 5th October I (Jayne) attended Tear Trough Training with Teosyal Redensity II. The training was intense and fabulous! if you want to know more, please contact me
Alumier is a medical grade skincare with active Ingredients that have an effect on the skin which can be ordered directly from Alumier using the code: 623W7ZF8
Forbes feet is a new range to pamper and delight your feet and is supplied by Protocol, please get in touch and I will pass along your order
We have invested heavily in PPE (Personal Protection Equipment) and complied with goverment guidelines to ensure we are able to offer our usual exceptional level of service safely to all our clients.
Please contact me:
One of the most celebrated ingredients in medical-grade skincare is vitamin C, and for good reason.
Read the editorial from HELLO and find out more...
Please contact Jayne directly below for more information
Contact Details
07977 138 242
Body Centre Clifton
68 Alma Rd, Bristol BS8 2DJ
0117 973 2790
Redcliffe Hair And Beauty
14-16 Queens Rd, Portishead, Bristol BS20 8HT
01275 848712
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JayneMolyneux.co.uk trading as Pure Clinic LTD. Registered in England & Wales. Co. Number 8165776.


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WIT 2019 Conference
Marina Bay Sands, Singapore
Singapore, Singapore
WIT is a community for anyone passionate about travel technology, distribution and marketing.
This basically means if you love travel, and if you are a bit of a technology freak in terms of wanting to understand how technology is changing travel, you are one of us.
WIT 2019 Conference is organized by webintravel.com


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Rodents Are Picked To Order The Day of Delivery to Guarantee Freshness.
We Feed only Top Quality 20% Protein Rodent Block
We Spare No Expense So You Get The Best Feeder Possible!
Due to the High Cost of Shipping, Customer Pickup at the listed locations is the economical and only choice at this time.
Instructions for Orders:
Place & Pay For Your Orders here on the website.
Pickup orders at either of the two pickup locations.
*** Please bring a cooler with frozen packs or ice to complete your journey home if you order frozen feeders.
Delivery: Wednesday Evenings Each Week:
5:30pm - 6:30pm: 2371 Corporation Parkway, Burlington NC (In the BMOC)
7:00pm - 8:00pm: 1601 Wiley Lewis Road, Greensboro NC


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Rodeway Inn Wahpeton (Est. 16 miles away)
Nightly Rate: $68 - $69
Hotel Features.
DAKOTA MAGIC CASINO HOTEL (Est. 16 miles away)
Nightly Rate: $70 - $71
Dakota Magic Casino And Hotel Features 117 guestrooms Including 10 Jacuzzi Rooms And 2 hospitality Suites, Designed For The Ultimate In luxury And Comfort....
Select Inn Breckenridge (Est. 17 miles away)
Nightly Rate: $59 - $61
Hotel Features.
AMERICINN WAHPETON (Est. 18 miles away)
Nightly Rate: $75 - $112
- Hotel - Limited Service year Built - 1996 additional Property Description - Located On The North Side Off The Hwy 210 Bypass, Americinn Wahpeton Has Been Recently Renovated With All New Carpet, Beds, Linens, Tvs And More. Spacious Guest Rooms, Wireless Internet, Meeting Rooms, Indoor...
Baymont Inn And Suites Wahpeton (Est. 18 miles away)
Nightly Rate: $77 - $102
Hotel Features.
Super 8 Wahpeton Nd (Est. 18 miles away)
Nightly Rate: $39 - $53
Hotel Features.
Comfort Inn Fergus Falls (Est. 27 miles away)
Nightly Rate: $82 - $93
Hotel Features.
AMERICINN FERGUS FALLS (Est. 27 miles away)
Nightly Rate: $73 - $129
- Hotel - Inn/Chalet - Limited Service year Built - 1995 Year Remodeled - 1997 additional Property Description - Welcome To Fergus Falls Join Us Monday Through Thursday At 5pm For Our Guest Reception With Food And Drinks. Americinn Offers Free Breakfast Featuring Sausage,...
AMERICAS BEST VALUE INN (Est. 27 miles away)
Nightly Rate: $39 - $54
Welcome To Americas Best Value Inn Of Fergus Falls, minnesota. Our Hotel Offers Unbeatable Service, An Attentive 24-Hour Front Desk Staff, And Competitive Rates. Our Indoor swimming Pool Is Open May Through September. Our Smoke-Free hotel Features An On-Site Guest Laundry Facility And Free daily Continental Breakfast....
SUPER 8 FERGUS FALLS MN (Est. 27 miles away)
Nightly Rate: $51 - $75
- Hotel year Built - 1977 Year Remodeled - 2004 additional Property Description - The Super 8 Of Fergus Falls Welcomes You To The City Where You Can Find Us, And Lose Yourself. Fergus Falls In Conveniently Located 2 1/2 Hours From Minneapolis/St. Paul And An Hour From Fargo/Moorhead Area. This...
BEST WESTERN THE FALLS INN (Est. 27 miles away)
Nightly Rate: $77 - $125
- Full Service - Hotel year Built - 1972 Year Remodeled - 2001 additional Property Description - Escape To This Fergus Falls, Minnesota Hotel And Enjoy Exceptional Accommodations And Convenient Access To Otter Tail Power, Red Horse Ranch Arena And...
SUPER 8 SISSETON (Est. 36 miles away)
Nightly Rate: $71 - $89
- Hotel year Built - 2003 additional Property Description - The Super 8 Sisseton Would Like To Welcome You To The Glacial Lakes Region. A Bustling City Of More Than 2,500. Sisseton Is Located On The Northeast Slopes Of The Coteau Des Prairies Where The Area S Natural Endowment Of Scenic Beauty Will Take...
Xanadu Island Bed and Breakfast and Restaurant (Est. 43 miles away)
Nightly Rate: $105 - $165
SUPER 8 MORRIS (Est. 44 miles away)
Nightly Rate: $53 - $101
- Hotel year Built - 1994 additional Property Description - University Of Minnesota, Morris - 6 Blocks--Indoor Pool And Whirlpool, Jacuzzi Suites, Andes Tower Ski Area - 45 Minutes, Snowmobile Trails, Super Start Breakfast, Free High Speed Internet...


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rederick Scholl, associate teaching professor of cybersecurity and director of the cybersecurity program at Quinnipiac, has some important advice for consumers on how they can protect themselves on Cyber Monday — and beyond.
"My motto for online shopping is 'only the paranoid survive,'" Scholl said. "That is an especially good rule of thumb on Cyber Monday, a day when everyone is in a hurry to get in on the best deals. People who are under stress can make mistakes. I almost spent $1,000 on a flashlight but caught the error just before I clicked. There are also many subtle ways people can be attacked beyond their computers because systems are not perfect and neither are we."


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chelfitsch & Teppei Kaneuji "Eraser Mountain"
About the event
chelfitsch & Teppei Kaneuji
Eraser Mountain (Theater), Eraser Forest (Museum)
Eraser Mountain: OCT. 5th (Sat),6th (Sun), 2019
Eraser Forest: FEB. 7th (Fri)~16th (Sun), 2020
@21st Century Museum of Contemporary Art, Kanazawa
What is theater released from a human scale?
People, objects, time, space, and language appear in unknown forms…
Playwright/Director: Toshiki Okada
Scenography: Teppei Kaneuji
Cast: Izumi Aoyagi, Mari Ando, Yuri Itabashi, Takuya Harada, Makoto Yazawa, Yo Yoshida, Leon Kou Yonekawa
Is it possible to create theater not only for the people watching at one moment in time? Can we use theater to present a world in which people and objects are completely equal, rather than trapped in their usual subservient relationship?
Devastated by the Great East Japan Earthquake in 2011, the city of Rikuzentakata in Iwate Prefecture is now undergoing immense reconstruction to elevate the area as a countermeasure against future tsunami waves and restore the lifestyles that the residents lost. However, the use of local rocks to raise the land more than ten meters (33 feet) higher than it was before has led to severe damage on surrounding mountains.
Visiting the area in 2017 and witnessing the landscape that had been so rapidly and artificially changed, Toshiki Okada started to conceive a new work in which he would raise doubts about the so-called criteria or measures that humans use. As his collaborator, Okada welcomes Teppei Kaneuji, the artist who has expanded the possibilities of his practice by voraciously incorporating theatrical perspectives into his main methodology of collage. The resulting work also integrates the "EIZO Theater" that chelfitsch has developed since last year, attempting to take yet another approach to language and the body of the actors. What is the landscape that emerges when we deviate from anthropocentrism?
Eraser Mountain is the very latest in chelfitsch's ongoing endeavors to update theater.
Ticket information
On sale July 26th (Fri) ,2019 11pm~
Adult Advance ¥4,000 / Day ¥3,500
Youth*, Students Advance ¥3,000 / Day ¥3,500
High School Students & Younger Advance and Day both ¥1,000
Pair ¥7,500 (Advance Only)
*Youth Tickets: available for those aged 25 and under
South Hall, ROHM Theatre Kyoto
13 Okazaki Saishoji-cho, Sakyo-ku, Kyoto, Japan 606-8342
Eraser Mountain
5th (Sat) 18:30-
6th (Sun) 14:00-*, 19:30-
*Post-performance Talk
Duration: 100min
*Performed in Japanese with English surtitles
South Hall, ROHM Theatre Kyoto
KYOTO EXPERIMENT: https://kyoto-ex.jp/home/
Eraser Forest
FEB. 7th (Fri)~16th (Sun),2020
21st Century Museum of Contemporary Art, Kanazawa
21st Century Museum of Contemporary Art, Kanazawa: https://www.kanazawa21.jp/
- Playwright/Director
- Toshiki Okada
- Scenography
- Teppei Kaneuji
- Cast
- Izumi Aoyagi
- Yuri Itabashi
- Takuya Harada
- Makoto Yazawa
- Yo Yoshida
- Leon Kou Yonekawa
- Costume
- Kyoko Fuzitani (FAIFAI)
- Lightinig Director
- Masayoshi Takeda (RYU)
- Sound Director
- Raku Nakahara (LUFTZUG)
- Video Designer
- Shimpei Yamada
- Technical Director
- Koro Suzuki
- Stage Manager
- Chikage Yuyama
- Assistant Director
- Nagara Wada
- Producer
- Tamiko Ouki (precog)
- Associate Producer
- Miyuki Tanaka
- Publicity Design
- Shota Yamauchi
- Flyer Design
- Yusuke Akai(paragram)
- Web Design
- Yosuke Hayashi(HAUS)
- Production
- chelfitsch
- Co-produced by
- [Eraser Mounrain] KYOTO EXPERIMENT, Wiener Festwochen, Festival d'Automne à Paris, Künstlerhaus Mousonturm Frankfurt
- [Eraser Forest] 21st Century Museum of Contemporary Art, Kanazawa
- Planning & Production Management
- precog co.,LTD.
- In co-operation with
- CONNELING STUDY/YAMABUKI FACTORY, Steep Slope Studio, Kyoto City University of Arts
- Kyoto Art Center Artists-in-Studios program
- This project consists of two versions, "Eraser Mountain" (premiere: October 2019 / KYOTO EXPERIMENT) and "Eraser Forest" (premiere: February 2020 / 21st Century Museum of Contemporary Art, Kanazawa).


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How to Make A Move Painfree
Moving can be tough. As most people know, I've moved several times. My move last month was unexpected but, to be honest, we found what we needed in a house. If we had known how the events of our previous house would play out, we probably would have kept looking last year. My apologies for not giving an exact reason of moving. We left on good terms with our landlords. Unexpected but good conditions.
Life happens and sometimes you need to roll with the punches! We only moved 4 miles away from our previous house.
A lot of people have asked: how do you prepare for so many moves?
The short answer is: Not accumulating a lot of junk.
But let's look at the long answer.
Here is my personal step process for an easy and relatively stressless move. Keep in mind this works for me but might not work for you!
Step 1: Clean out your current house. Every move I use as an excuse to see what I'm not wearing or using. If I haven't worn or used something since the last move, it gets donated. Someone else will use it more than I am! We have started cleaning and sorting about one month before leaving. We give away items we haven't used in a year.
Step 2: Take one room at a time. We conquer each room one day at a time. We have each room scheduled of when we are going to pack it. That way the move doesn't get too overwhelming. We can also take our time figuring out what we need and don't need. This process starts about two weeks before the actual move. Our previous house had eight rooms, and it took us about ten days.
- Important to note during Step 2: It's important to make sure essential items stay away from the packed items. Personally, we have a lock box with our valuable items as well as passports, important documents, and extra car keys. You don't want those to pack those.
- Also important to note is inventory everything. We label each box with the room it's going. We also number the box and have a master list on the computer. The last thing you want it to get to your new destination and be trying to figure out which box went missing.
Step 3: This is the part where you pack up everything and move from house to house…I have done a 4-mile move and I have done 3000-mile moves. It's about the same: Move all of your boxes from one house to the other.
Step 4: Unpack in the new house. If you've labeled your boxes by room, this makes it a lot easier. You can quickly drop off items in the appropriate room.
It's safe to say after three weeks of living in our new house we are nearly unpacked. After I had taken a nasty fall the weekend we moved, I lost some motivation to unpack. When you have a giant piece of your flesh missing, you seem to be more lazy than normal (So I've heard). It might have taken us a little bit longer to unpack, but no move, training cycle or anything is that perfect.
Questions for you:
What advice do you have for people moving?
What are the shortest moves and longest moves you have done?
For me, the shortest was now, and the longest was when I was a child from the UK to the US (but maybe that doesn't count since mom did most of that).


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On the Shelf
America The Great Cookbook
Edited by Joe Yonan
What happens when 100 (mostly) revered food heroes and chefs are asked what foods they prepare for their loved ones? We get this beautiful book. Featured contributors, such as Carla Hall, Ruth Reichl, and Marcus Samuelsson, give the reader a peek at their lives and how they turn their craft inward to honor the people they care about the most. Recipes explore each contributor's home region, including local ingredients and time-honored traditions. By the time you're done reading, you will have traveled across the country and enjoyed Sunday dinner with 100 new friends. A portion of this book's sales proceeds benefit No Kid Hungry, an organization that provides children with nutritious meals and teaches families how to shop and cook for themselves on a budget. This collectible book offers delicious recipes, compelling stories, and stunning photography while helping our food-insecure population.
The Recipe Box
By Viola Shipman
Award-winning author Wade Rouse chose Viola Shipman as his pen name to honor his grandmother, whose heirlooms and family stories inspire his fiction. In The Recipe Box, Rouse introduces us to Sam Mullins, a young woman who feels trapped working at her family's pie shop. After a brief escape to New York City goes awry, Sam returns home, resigned to give working for the family business one more shot. She soon discovers a treasure trove of family history hidden in her mother's and grandmother's recipes. Rouse's talent for bringing his characters to life—especially Willo, Sam's feisty grandmother—elevates this book. The inclusion of actual heirloom recipes, such as rhubarb sour cream coffee cake and pumpkin bars with vanilla cream cheese frosting, are a delicious bonus.
Salt, Fat, Acid, Heat
Mastering the Elements of Good Cooking
By Samin Nosrat
If you are like me, cooking is key to relaxing. Planning and preparing food for family and friends gives me a huge sense of accomplishment (especially if they enjoy it). It's a great stress reliever. I often spend Sundays learning new culinary techniques and experimenting with new dishes. This book is my new culinary companion. The author has taken a unique approach to identify the basics of each of the titular cooking elements, and encourages beginning and advanced cooks to incorporate each into their cooking—without using detailed recipes. Also included are sample recipes to help cooks experiment. Throughout the book are charming illustrations that help visualize the concepts. Even longtime home cooks can learn new tricks. Nosrat has created not only a very accessible and encouraging cookbook, but also an essential one.
—Ronald Block, Cuyahoga County Public Library


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So pretty. So smelly. Must be a Venice canal.
That's what I'd always been told anyway.
Actually, I think the smelliness of Venice is greatly overstated. Yes, it's true that if you get up close there's a bit of a dirty seawater odour, but it's only in certain places and it's hardly overwhelming.
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Our Airbnb was on a canal and we had our bedroom window open all night and it was positively pleasant.
Until a delivery boat parked right below us very early in the morning and the deliverymen started shouting at each other as they unloaded…


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N.A.T.B. Dogs Sports is a National amateur sports club that was formed by individuals who felt there was a growing need for positive promotion of dog-related sports in a non-biased, friendly and constructive manner. We are open to inviting new members to join our club if we feel they have similar attitudes and are willing to abide by our club's Code of Conduct and Trail Etiquette.
About our Members:
N.A.T.B. Dog Sports is a club of champions but you don't need to be a champion to be part of our club, you just need to know how to have fun with your dog and eat cake!
We are a very proud and friendly club and are privileged to be able to tap into the wealth of experience and knowledge provided from within our membership, many members have been participating for many years in the various dog sports disciplines we cover. So, whether you are just starting out or already have 20+ years' of experience, you would be a valued member of our club.
We are proud to be sponsored by Paws, Play & Stay. Exeter Canine Hydrotherapy Treadmill and K9 Fitness.
Our events are proudly sponsored by the awesome company Edgar Cooper. They provide us with their awesome food, not only in our goodie bags as testers but also as first prize awards and a discount code for all competitors. We thank them massively and confirm our dogs love their food, and we know its the best for them!
We are also extremely excited to be affiliated with Cotswold Outdoors giving our members wonderful discounts, just another reason to become an NATB!
We are, of course, willing to help out and share knowledge and experience with non-members of the club too (even more willing when bribed with cake!), so please do come and speak to us, contact us via Facebook PM or email us.
Details: firstname.lastname@example.com if you are interested in becoming a member. o
Contact Us


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Shimano Peddles a Soft Sell
Bike enthusiasts, whether city commuters, spandex-bedecked road cyclists, dirt-loving mountain bikers or all others that fall in between, are a supremely cliquish, predictable breed, and are no less so as consumers. Show us anything that resembles a crank or spoke or calls to mind the passion that motivates us to ride, and we salivate and feel a kinshiplike members of an elite club.
So it's no surprise that when I received this 5-1/2" x 7-1/2" four-panel self-mailer with the picture of a man in a business suit and helmet riding a bike into his company parking lot, I was both thrilled and intrigued. Obviously the sender knew me well enough to know I'd be among the thrilled, which made me beam even more. And I was intrigued because I could see from the start that I had a top mailing in my hands, from the use of enticing photography to the motivational copy and pillow-soft sell.
The mailing was sent by Shimano, an international cycling and fishing parts and products provider, to promote Bike to Work Week, an initiative to encourage cycling, sponsored by Shimano, the League of American Bicyclists and various local cycling organizations in 15 participating, cyclist-populated cities (Archive code #910-701149-0505).
Spot-glued together, the interior of the four-color self-mailer opens to reveal a photo on the left panel of a mud-splattered business woman giving a work presentation, surrounded by unfazed onlookers.
The right panel lists in poetic-verse form the various reasons to ride to work, with the word "ride" colored in blue for emphasis:
Ride for the planet. Ride for your city. Ride for you and you alone. Ride to be a hero to kids in passing school buses ...
The back panel shows a list of bike shops in the prospects' area and offers a free coffee tumbler when recipients get a tune-up at one of the shops and test a bike equipped with Shimano's new Nexus components.
According to Dustin Brady of Shimano consumer marketing promotions, the mailing was a combined effort with Rodale, publisher of Bicycling Magazine and organizer of Bike Town USA, an effort similar to Bike to Work Week, where members of a town are selected to receive bicycles and take part in an experiment to show what happens when people incorporate biking into their lives. Shimano used Rodale's database to reach cycling enthusiasts, says Brady, because the individuals on their lists are enthusiasts and influencers who reach out and get their neighbors to ride.
The mailing's purpose, says Brady, was to promote Bike to Work Week and get people to support their local bicycle dealers. Once prospects get into the local shops, the soft sell of encouraging them to become familiar with Shimano's Nexus component line serves more as a long-term investment to build awareness of new products, he adds.
And Brady seems confident that direct mail is the best way to build that awareness. "Last year we did radio spots, weekly ads and direct mail in five markets," says Brady, "and we saw higher return on the direct mail, so we took out our other media buys."


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Leadership Rising Up: visions for the future by Shirlee Harel The young generation in Israel has spoken. For too long, young Israelis returned from their post-army travels with a sense of indifference and complacency. Recent outbursts of public protests around Israel have … [Read more...] about Leadership Rising Up
Israel's Summer of Protest
Marching Alone
400,000 people thronged the streets of Israel to protest the social situation while Jews in America remained silent. by Tuval Chesler The year was 1965: the height of the civil rights movement demanding equality for African Americans in the United States. In the town of … [Read more...] about Marching Alone
Israeli Social Protests: A Challenge of Hope to Diaspora Jewry
by Robert Hyfler Saturday night, 450,000 Israelis, including the largest number of people to ever sing Hatikvah in one place at one time, gathered under the slogan "ha'am doresh tzedek chevrati" - the nation demands social justice. 450,000 Israelis, mostly young, but not all … [Read more...] about Israeli Social Protests: A Challenge of Hope to Diaspora Jewry
Leadership and Israel's New Social Contract
by Shirlee Harel Mahatma Gandhi recognized an essential component of effective leadership: "We must become the change we want to see in the world". Leaders should lead by example in a manner that reflects their ideals and hopes for the future. However, today we see many modern … [Read more...] about Leadership and Israel's New Social Contract
Rothschild on the Hudson: An Israeli in NY Inspired by J14
by Uri Leventer-Roberts "My heart is in the East, and I am at the ends of the West." Never have the words of the 12th century Jewish poet and writer Yehuda Halevi resonated more with me than in the past four weeks. Halevi wrote about the challenge of living in prosperous Spain … [Read more...] about Rothschild on the Hudson: An Israeli in NY Inspired by J14


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Ambient Air Heated Forced Draft Vaporizers
The performance of ambient forced draft air heated vaporizers, which use the relative ââ¬Åheatââ¬Â of the atmosphere to derive the energy necessary for the vaporization of the liquid cryogen, is subject to many factors. These include flow rate, duty cycle, ambient temperature, relative humidity, freeze period, altitude, wind, solar radiation, operating pressure and proximity to adjacent structures. The effects of average solar and wind conditions are not included in quoted ratings. Performance is based on mean ambient conditions of 70 0F (210C) and 70% relative humidity. Special conditions may vary considerably for different application, thereby affecting performance. Ambient forced draft vaporizers represent the most cost effective equipment to vaporize or re-gasify liquid cryogens. Once installed there are minimal maintenance costs. All that is required is regular defrosting of the heat transfer elements.
LOW PRESSURE standard all aluminum units MAWPs available: 275 psig (19 bar); 450 psig (31 bar); 588 psig (40 bar) Other MAWPs on request
Connections: Mueller four bolt, ANSI RFWN or SORF or DIN specification flanges.
HIGH PRESSURE standard all aluminum ââ¬Ëmetal linedââ¬â¢ units MAWPs available: 3600psig (250 bar) and 6000psig (400 bar) Models available up to 15,000psig (1000 bar). Connections: SCBW (square cut butt weld); ýââ¬Â NPTF; others on request. Liner materials available: Types 304, 316 and 310 Stainless Steel, Monel, other materials on request.
All ISPL vaporizers are designed and manufactured in accordance with the UBC and applicable sections of ANSI A 58.1. Units available for seismic zone 4 locations and 100mph (44m/s) wind speed with normal ice loading. Vaporizers may be manufactured in compliance with any internationally recognized pressure specification, such as ASME; TUV; PED; KGC or ISQL. ASME U STAMP VAPORIZERS AVAILABLE.
INCRYO SYSTEMS PVT. LTD. All Rights Reserved.(Terms of Use)
Developed and Managed by Infocom Network Ltd.


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- Essential Oil Singles
- >
- 15ml Conventional Tangerine
15ml Conventional Tangerine
Country of Origin: USA, Conventionally Grown
Botanical Name: Citrus reticulata
Plant Part: Peel
Note: Fresh, Citrus, Sweet, Fruity
Man Found Standing, Medicine Man Practitioner writes: Tangerine is one of the few essential oils that has a very limited supply of certified organic material. Because of this, the cost of the organic oil is many times more expensive than the conventionally grown. Any company saying they are selling Organic Tangerine is probably not telling the truth unless that oil is many times more expensive than the standard conventional pricing. This is one of the oils I like to look at when trying to determine if a company is telling the truth or selling low quality, adulterated essential oils. For greater details, see the picture printout from my book. Historically Tangerine has been used to assist in:
- Nervous System: stress, anxiety
- Digestive Aid: constipation, laxative, flatulence, intestinal spasms, detoxifier
- Lungs: congestion, coughs, decongestant
Extraction Method: Cold Pressed
Historic Benefits: The oil from the peel was use as a general health tonic and to uplift and elevate the mind.
Blends Well With: Cedarwood, Chamomile, Citrus, Clary Sage, Frankincense, Geranium, Lavender, Rose, Sandalwood, Ylang Ylang
Precautions: Phototoxic and skin irritant to sensitive individuals.


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Backlash after French female celebrities criticise #MeToo
Issued on: Modified:
IN THE WORLD PAPERS - Wednesday, January 10: The international backlash continues after French female celebrities condemn the #MeToo movement as puritanism. Also, Benjamin Netanyahu's son is embroiled in a scandal some are calling "Strippergate". And sales soar of a Canadian author's book about the Second World War, "Fire and Fury", after people mistakenly purchase it instead of Michael Wolff's tell-all blockbuster about Donald Trump!
Le Monde's piece has got everyone talking today. In an open letter, a group of prominent French women - including actress Catherine Deneuve - condemn the #MeToo movement as "puritanism" that has essentially blurred the lines between sexual harassment and flirty behaviour. In their opinion, "a woman can, in the same day, manage a team of people and enjoy being the sexual object of a man, with being qualified as a 'whore' nor as a vile accomplice of the patriarchy". They go on to say "a woman can fight for an equal salary, but not feel traumatised by someone who brushes up against her in the metro, even if that is a crime".
Also, Israeli Prime Minister Benjamin Netanyahu is embroiled in a new scandal - this time involving his eldest son Yair, an audio tape recording, a debaucherous night on the town and his friend's super-rich father, with whom Benjamin Netanyahu did business deals. Haaretz has a great explainer here.
And people looking to pick up a copy of Michael Wolff's salacious Donald Trump tell-all have been buying the wrong book! Vice reports that Canadian author Randall Hansen has seen sales soar of "Fire and Fury" - his one, though, is about the Allied bombing of Germany during the Second World War!
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On the Blog
Posts Categorised: Progesterone and Cancer
Many people have a misconception that progesterone and synthetic progestins (as found in HRT and the pill) is the same hormone.
They are not!
This confusion, even among certain health care professionals, misleads into believing that natural progesterone poses a cancer threat.
Studies published in 1995 found that women who had been exposed to HRT for longer than 5 years had a 32% increased risk of getting breast cancer. If the estrogen was combined with a progestin, it went up to 41%, and for those women who were post-menopausal the risk went up to 71%, while the risk of getting ovarian cancer went up by 72%. Further sub analysis showed that the SYNTHETIC PROGESTIN was actually the culprit causing the increased breast cancer risk. (Source Dr Anna Garrett)
Clinical studies by the Emory University suggest that progesterone is a beneficial and effective hormone. The University has been investigating this hormone for the last 20 years. A study conducted in 2006 on the victims of traumatic brain surgery also established that progesterone is effective in reversing the brain oedema after the injury. Progesterone showed no harmful side effects on the victims.
There are many studies that suggest how progesterone protects from cancer by activating the gene p53. Abnormal cells keep growing and multiplying when this gene is inactive.
Too much estrogen is known to trigger heart diseases and cancer. Progesterone protects from cancer by slowing down the production of the estrogen.
Various studies highlight the protective function of progesterone in the body. It prevents hypertension, lowers blood fat, prevents coronary artery disease, protects from endometrial and ovarian cancer, and epilepsy. The presence of progesterone in the body is essential for a healthy pregnancy as well as preventing miscarriages, it also aids in vasomotor symptoms.
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Progesterone protects from Cancer
The alarmingly increased rate of cancer is a result of pollution, toxins from agriculture and industry, processed foods and increase usage of prescription medicines such as estrogen. Studies reveal that only 5% of cancer is heredity.
A study in 2002 also revealed that the increasing occurrence of cancer in humans is due to a lack of UV-B and vitamin D3. Experts suggest by having careful exposure of sun and taking vitamin D supplements regularly can help in reducing the rate of cancer. Progesterone and vitamin D are of similar nature and studies suggest that a lack of vitamin D reduces the benefits of progesterone.
Exposure to high level of estrogen can result in cancers of the breast, ovaries, and endometriosis in women and prostate, testicular, and breast cancer in men.
The studies also highlight the fact that the longer a woman is exposed to her own natural estrogens, she will be at a greater risk of developing breast cancer. Women who have low levels of progesterone are 5% more at risk of developing cancers.
How much progesterone to use?
The daily recommended progesterone dosage for women is 100 -200 mg daily, and for men it is between 10 – 100 mg per day. However the dosage should be increased until the estrogen dominance symptoms are taken care of. Progesterone can be used to sooth the radiation burn of radio-therapy and regenerate the skin. Progesterone is neuro protective agent as well as prevents lipid per-oxidation and protects the vascular system. This hormone works as an anti-inflammatory agent and is known to reduce the response of natural killer cells.
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Good News!!..But how long have people been saying this!!
Women with breast cancer could benefit from taking progesterone, after research discovers how it modulates the actions of the estrogen receptor.
Researchers have discovered why breast cancer patients whose tumours display both oestrogen and progesterone receptors have the best chance of survival, which has long been observed but not understood.
The finding could benefit up to half of all breast cancer patients, leading to the development of a hormone treatment that is cheap, safe and widely available.
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It has long been known that tumours with oestrogen receptors (ER) and progesterone receptors (PR) (ER/PR double positive) have the best clinical outcome, but the interplay between the two proteins has remained unknown. Both are transcription factors, which means they are both involved in switching genes on and off in cells.
Breast cancer cells have increased sensitivity to oestrogen. Once oestrogen has bound to ER on the surface of these cells, the ER enters the cell and ends up in the nucleus, where it attaches to specific regions of DNA, switching on transcription of a group of genes that promote cell division and hence tumour growth.
Exactly what the PR does – if anything – while this is happening has remained unclear. All that was known was that the presence of these receptors would slow tumour growth. Now, Jason Carroll of Cancer Research UK's Cambridge Research Institute and colleagues, have taken a closer look.
"We've used cutting-edge technology to tease out the crucial role that progesterone receptors play in breast cancer — a mystery that has baffled scientists for many years," says Carroll. "This important laboratory research helps explain why some breast cancer patients have a better outlook."
The team grew breast cancer cells that displayed both ER and PR in the laboratory, and made sure the cells had enough oestrogen and progesterone to bind to the receptors. The researchers then removed the PR (which had bound to progesterone) from the cells, and were surprised to find that the PR was now bound to the ER.
Since both receptors are transcription factors, Carroll's team investigated whether this unexpected binding would affect gene transcription. They examined where the ER would attach to DNA in the absence of progesterone, and looked at where the ER would attach to DNA in the presence of progesterone and its receptor.
The researchers found that the receptor bound to different regions of DNA depending on whether progesterone was present. In other words, the PR (that had bound to progesterone) was changing the genes that the ER was switching on or off. Alongside this, the researchers saw that progesterone was associated with a slowing of cancer cell growth. The pattern was seen again in studies with different cancer cells and in mice.
The findings are particularly exciting because progesterone, which slowed tumour growth in both cells and in an animal model, is a cheap, safe, and widely available drug.
"These findings are an exciting development in our understanding of how hormones may make certain breast cancers grow," says Samia al Qadhi, chief executive of the breast cancer support charity, Breast Cancer Care.
source: pharmaceutical-journal.com
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