text:
Personalized Kinase Inhibitor Therapy Combined With Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT02779283
Recruitment Status : Completed
First Posted : May 20, 2016
Last Update Posted : May 26, 2020
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
|Condition or disease
|Acute Lymphoblastic Leukemia Acute Myeloid Leukemia
|Drug: Cyclophosphamide Drug: Cytarabine Drug: Dasatinib Drug: Dexamethasone Drug: Doxorubicin Hydrochloride Drug: Idarubicin Drug: Idelalisib Device: In Vitro Kinase Inhibitor Assay Drug: Leucovorin Calcium Drug: Methotrexate Drug: Methylprednisolone Sodium Succinate Drug: Ponatinib Hydrochloride Biological: Rituximab Drug: Ruxolitinib Phosphate Drug: Sorafenib Tosylate Drug: Sunitinib Malate Drug: Vincristine Sulfate
|Phase 1
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|7 participants
|Intervention Model:
|Parallel Assignment
|None (Open Label)
|Primary Purpose:
|Official Title:
|A Phase Ib Feasibility Study of Personalized Kinase Inhibitor Therapy Combined With Induction in Acute Leukemias Who Exhibit In Vitro Kinase Inhibitor Sensitivity
|Actual Study Start Date :
|January 13, 2016
|Actual Primary Completion Date :
|April 19, 2018
|Actual Study Completion Date :
|September 20, 2018
Experimental: Arm I (AML)
Patients receive cytarabine IV continuously over 24 hours on days 1-7, and idarubicin IV over 30 minutes on days 1-3.Patients receive cyclophosphamide IV over 3 hours twice daily (BID) on days 1-3, vincristine sulfate IV on days 4 and 11, doxorubicin hydrochloride IV on day 4, dexamethasone PO on days 1-4 and 11-14, and rituximab IV on day 1 and 11 (day 11 only of course 1). Treatment repeats every 28 days for up to 4 courses in the absence of disease progression or unacceptable toxicity. Based on the results of the kinase inhibitor assay (In Vitro Kinase Inhibitor Assay), patients receive either sorafenib tosylate PO BID, sunitinib malate PO daily, dasatinib PO daily, ponatinib hydrochloride PO daily, ruxolitinib phosphate or idelalisib PO BID on days 8-28 in the absence of disease progression or unacceptable toxicity.
Drug: Cytarabine
Given IV
Other Names:
Drug: Dasatinib
Given PO
Other Names:
Drug: Idarubicin
Given IV
Other Names:
Drug: Idelalisib
Given PO
Other Names:
Device: In Vitro Kinase Inhibitor Assay
Correlative studies
Other Name: Laboratory Biomarker Analysis
Drug: Ponatinib Hydrochloride
Given PO
Other Names:
Drug: Ruxolitinib Phosphate
Given PO
Other Names:
Drug: Sorafenib Tosylate
Given PO
Other Names:
Drug: Sunitinib Malate
Given PO
Other Names:
Experimental: Arm II (ALL)
Patients receive cytarabine IV over 2 hours BID on days 2-3, methotrexate IV over 2-22 hours on day 1, methylprednisolone sodium succinate IV BID on days 1-3, leucovorin calcium IV every 6 hours until methotrexate level is < 0.05 uM and rituximab IV on days 1 and 8. Treatment repeats every 28 days for up to 4 courses in the absence of disease progression or unacceptable toxicity. Based on the results of the kinase inhibitor assay (In Vitro Kinase Inhibitor Assay), patients receive either sorafenib tosylate PO BID, sunitinib malate PO daily, dasatinib PO daily, ponatinib hydrochloride PO daily, ruxolitinib phosphate or idelalisib PO BID on days 8-28 in the absence of disease progression or unacceptable toxicity.
Drug: Cyclophosphamide
Given IV
Other Names:
Drug: Cytarabine
Given IV
Other Names:
Drug: Dasatinib
Given PO
Other Names:
Drug: Dexamethasone
Given PO
Other Names:
Drug: Doxorubicin Hydrochloride
Given IV
Other Names:
Drug: Idelalisib
Given PO
Other Names:
Device: In Vitro Kinase Inhibitor Assay
Correlative studies
Other Name: Laboratory Biomarker Analysis
Drug: Leucovorin Calcium
Given IV
Other Names:
Drug: Methotrexate
Given IV
Other Names:
Drug: Methylprednisolone Sodium Succinate
Given IV
Other Names:
Drug: Ponatinib Hydrochloride
Given PO
Other Names:
Biological: Rituximab
Given IV
Other Names:
Drug: Ruxolitinib Phosphate
Given PO
Other Names:
Drug: Sorafenib Tosylate
Given PO
Other Names:
Drug: Sunitinib Malate
Given PO
Other Names:
Drug: Vincristine Sulfate
Given IV
Other Names:
- Proportion of subjects who start a targeted drug [ Time Frame: On day 8 ]A proportion of subjects whose targeted drug is identified and who start the kinase-inhibitor drug on day 8 will be estimated among all screened subjects along with the 95% confidence interval using the feasibility analysis set.
- Incidence of any grade 3 or higher dose limiting toxicity graded (DLT) according to Common Terminology Criteria for Adverse Events version 4.0 [ Time Frame: Up to 6 weeks post-treatment ]DLT events will be tabulated and summarized. The incidence of DLT and its 95% confidence interval will be provided for the entire safety analysis set as well as for each targeted drug separately.
- Overall objective response rates defined as morphologic, cytogenetic and molecular complete response (CR) rates at the end of induction period [ Time Frame: At 14 days post-induction treatment ]The proportion and its 95% confidence interval will be provided for morphologic CR rate, cytogenetic CR rate, and molecular CR rate at the end of induction period. The descriptive statistics (mean, standard deviation, median, minimum and maximum) will be provided for % blasts at day 14 (+/- 3 days) for acute myeloid leukemia or show signs of disease progression requiring alternative treatment (re-induction) during the 21 day targeted treatment period (days 8-28) for acute lymphoblastic leukemia. The proportion and its 95% confidence interval will be provided for the proportion of patients who show sensitivity to each of the study drugs (i.e., IC50 < 20% of median IC50).
- Proportion of patients who show sensitivity to each of the study kinase inhibitors [ Time Frame: Baseline ]Measured as half maximal inhibitory concentration (IC50) < 20% of median IC50.
- Overall survival [ Time Frame: From date of the first treatment assessed up to 1 year ]Kaplan-Meier method will be used to estimate overall survival.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years to 64 Years (Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Patients must have histologically confirmed AML or ALL, excluding acute promyelocytic leukemia (APL); for histological confirmation, a bone marrow biopsy and aspirate must be reviewed at Oregon Health & Science University (OHSU)
- Patients must have newly diagnosed AML or ALL without previous treatment; hydroxyurea will be allowed to control peripheral blast count as clinically indicated but would need to be stopped prior to initiation of tyrosine kinase inhibitor [TKI]); all-trans retinoic acid (ATRA) is permitted during the period prior to ruling out a diagnosis of APL; previous radiation treatment is allowable; patients must be deemed eligible for treatment with cytotoxic induction chemotherapy with cytarabine and idarubicin for AML or hyper-cyclophosphamide, dexamethasone, doxorubicin, vincristine sulfate (CVAD) for ALL; patients newly diagnosed with ALL must have received no prior treatment for their ALL with the exception of steroids (i.e. prednisone, dexamethasone); intrathecal methotrexate or cytarabine, allowed prior to and throughout the enrollment period for AML and ALL
- Subjects must be aged between >= 18 years and =< 64 for AML and > 40 and =< 64 for ALL
- Eastern Cooperative Oncology Group (ECOG) performance status =< 2
- Total bilirubin < 2.0 x institutional upper limit of normal (ULN)
- Aspartate aminotransferase (AST) (serum glutamic oxaloacetic transaminase [SGOT]) and alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase [SGPT]) =< 2.5 x institutional ULN and thought to be due to hepatocellular dysfunction
- Potassium > lower limit of normal (LLN) or correctable with supplements prior to first dose of study medication
- Magnesium > LLN or correctable with supplements prior to first dose of study medication
- Total calcium (corrected for serum albumin) >= LLN or correctable with supplements prior to first dose of study medication
- Serum amylase and lipase =< 1.5 x institutional ULN
- International normalized ratio (INR) =< 2.0 or correctable to 2.0 with vitamin K therapy
- Corrected QT (QTc) =< 450 msec. for men or QTc =< 470 msec. for women
- Creatinine < 2.0 x ULN
- No clinically significant uncontrolled infections as determined by investigator
- Patients must be able to take oral medications
Persons of reproductive potential must agree to an adequate method of contraception throughout treatment and for at least 4 weeks after study drug is stopped
- Women of childbearing potential must have a negative serum or urine pregnancy test within 8 days prior to start of study drug administration
- Patients must be willing to accept blood product transfusions
- Ability to understand and the willingness to sign a written informed consent document and Health Insurance Portability and Accountability Act (HIPAA) documentation
- Women of childbearing potential (WOCBP) must have a negative serum or urine pregnancy test (minimum sensitivity 25 IU/L or equivalent units of human chorionic gonadotropin [HCG]) within 24 hours prior to the start of study drug
- Women must not be breastfeeding
- WOCBP must agree to follow instructions for method(s) of contraception for the duration of treatment with study drug, plus 30 days (duration of ovulatory cycle) for a total of 30 days post-treatment completion
- Men who are sexually active with WOCBP must agree to follow instructions for method(s) of contraception for the duration of treatment with study drug plus 90 days (duration of sperm turnover) for a total of 90 days post-treatment completion
- Azoospermic males and WOCBP, who are not heterosexually active, are exempt from contraceptive requirements; however, WOCBP must still undergo pregnancy testing
- Investigators shall counsel WOCBP and male subjects who are sexually active with WOCBP on the importance of pregnancy prevention and the implications of unexpected pregnancy; investigators shall advise WOCBP and male subjects who are sexually active with WOCBP on the use of highly effective contraception; highly effective methods of contraception have a failure rate of < 1% when used consistently and correctly
- At a minimum, subjects must agree to the use of two methods of contraception, with one method being highly effective and the other method being either highly effective or less effective
Exclusion Criteria:
- Newly diagnosed AML patients who are identified with FLT3-ITD or tyrosine kinase domain (TKD) point mutation in the codon for an aspartate (D835) or an isoleucine (I836) residue
- Patients with a diagnosis of Philadelphia chromosome (Ph)+ ALL are not eligible
- Subjects who are currently receiving any other investigational agents
- History of allergic reactions attributed to compounds of similar chemical or biologic composition to study agent or other agents used in the study
- Drugs that affect the cytochrome P450 family 3, subfamily A, polypeptide 4 (CYP3A4) systems are allowed but should be used with caution depending on specific kinase inhibitor used
- All outside study medications and supplements will be reviewed and monitored by the inpatient pharmacy team; patients will be discouraged from taking herbals and additional supplements
Patients should not be prescribed concomitant medications that may contribute to prolonged QTc without consultation with the chemotherapy pharmacist; additional ECGs should be done at the investigator?s discretion to ensure the subject?s safety; drugs that are generally accepted to increase the risk of Torsades de Pointes, include (but not limited to):
- Quinidine, procainamide, disopyramide
- Amiodarone, ibutilide, dofetilide, sotalol
- Erythromycin, clarithromycin
- Chlorpromazine, mesoridazine, thioridazine, pimozide
- Cisapride, bepridil, droperidol, methadone, arsenic, chloroquine, domperidone, halofantrine, levomethadyl, pentamidine, sparfloxacin, lidoflazine
- Left ventricular ejection fraction < 50%
- Uncontrolled intercurrent illness including but not limited to, symptomatic New York Heart Association (NYHA) class III congestive heart failure, uncontrolled angina pectoris, myocardial infarction or stroke within 6 months prior to enrollment, or psychiatric illness/social situations that would limit compliance with study requirements
- Patients with a known human immunodeficiency virus (HIV) diagnosis are excluded from the study
- History of hypersensitivity to any of the kinase inhibitors included in this study
- Pregnant or lactating women are excluded from the study
- Diagnosed congenital long QT syndrome
- Any history of significant bleeding disorder unrelated to cancer, including any congenital bleeding disorder or any acquired bleeding disorder within one year of start of study
- Any history of clinically significant ventricular arrhythmia (such as ventricular tachycardia, ventricular fibrillation or torsade de pointes)
- Patients must not have clinically significant malabsorption syndrome or history
- All patients must discontinue anti-platelet agents or anticoagulants 7 days prior to initiation of study drug
- All patients with unhealed wounds or fistulas should not be given vascular endothelial growth factor (VEGF) inhibiting TKIs
- Patients with cytogenetically ?favorable risk' AML (core-binding factor leukemias) will not be enrolled on the ponatinib arm; testing with cytogenetics and fluorescence in situ hybridization (FISH) can establish this subtype within 7 days of the diagnostic bone marrow biopsy
- History of acute pancreatitis within 1 year of study or history of chronic pancreatitis
- Uncontrolled hypertriglyceridemia (triglycerides > 450 mg/dL)
Any history of myocardial infarction, stroke, or revascularization
- Any history of venous thromboembolism including deep venous thrombosis or pulmonary embolism with the exception of upper Extremity/Line associated deep vein thrombosis (DVTs) which are adequately treated (line removed and/or patient anti-coagulated)
- Uncontrolled hypertension (diastolic blood pressure > 90 mm Hg; systolic > 140 mm Hg); patients with hypertension should be under treatment on study entry to effect blood pressure control
- Any history of second or third degree heart block (may be eligible if the subject currently has a pacemaker)
- Known pulmonary arterial hypertension
- Patients may not have clinically significant pleural or pericardial effusion per provider discretion
- Major surgery, open biopsy, or significant traumatic injury within 30 days
- Non-healing wound, ulcer, or bone fracture
- Thrombotic or embolic venous or arterial events, such as cerebrovascular accident, including transient ischemic attacks, arterial thrombosis, deep vein thrombosis and pulmonary embolism within the past 6 months
- Upper Extremity/Line associated DVTs which are adequately treated (line removed and/or patient anticoagulated) are eligible
- Uncontrolled hypertension
- Active bleeding during screening
- Hypersensitivity to sorafenib
- Ongoing drug-induced liver injury, chronic active hepatitis C (hepatitis C virus [HCV]), chronic active hepatitis B (hepatitis B virus [HBV]), alcoholic liver disease, non-alcoholic steatohepatitis, primary biliary cirrhosis, extrahepatic obstruction caused by cholelithiasis, cirrhosis of the liver, portal hypertension, or history of autoimmune hepatitis
- Ongoing symptomatic pneumonitis
- Ongoing inflammatory bowel disease or autoimmune colitis
- Ongoing cytomegalovirus (CMV) infection, treatment, or prophylaxis within the past 28 days prior to the screening test for active CMV
- History of serious allergic reaction including anaphylaxis and epidermal necrolysis
- Chronic active hepatitis C (HCV)
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02779283
|United States, Oregon
|OHSU Knight Cancer Institute
|Portland, Oregon, United States, 97239
|Principal Investigator:
|Stephen Spurgeon
|OHSU Knight Cancer Institute
|Responsible Party:
|Stephen Spurgeon, Principal Investigator, OHSU Knight Cancer Institute
|ClinicalTrials.gov Identifier:
|Other Study ID Numbers:
NCI-2016-00083 ( Registry Identifier: CTRP (Clinical Trial Reporting Program) )
IRB00011766 ( Other Identifier: OHSU Knight Cancer Institute )
P30CA069533 ( U.S. NIH Grant/Contract )
|First Posted:
|May 20, 2016 Key Record Dates
|Last Update Posted:
|May 26, 2020
|Last Verified:
|February 2020
|Studies a U.S. FDA-regulated Drug Product:
|Studies a U.S. FDA-regulated Device Product:
Leukemia, Myeloid
Leukemia, Myeloid, Acute
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Leukemia, Lymphoid
Neoplasms by Histologic Type
Lymphoproliferative Disorders
Lymphatic Diseases
Immunoproliferative Disorders
Immune System Diseases
Calcium, Dietary
Folic Acid
Methylprednisolone Acetate
Methylprednisolone Hemisuccinate
Prednisolone acetate
Dexamethasone acetate
Liposomal doxorubicin


text:
Government rejects Hackney Council's defence of 'fortnightly' freesheet
The government has set out its reasons for rejecting Hackney Council's defence of its fortnightly freesheet in a letter to the Town Hall.
The Department for Communities and Local Government (DCLG) this week threatened the council with legal action if it does not stop publishing Hackney Today "so frequently" by February next year.
The council has ignored previous government orders to cut publication to quarterly.
In a letter to Town Hall chief executive Tim Shields, a senior civil servant said 24 editions of the freesheet every year was "far in excess of the recommended four".
Alex Powell, DCLG's deputy director of Local Government Stewardship, said communities secretary Sajid Javid rejected Hackney Council's argument that its freesheet does not compete unfairly with local papers.
Powell wrote: "He [Javid] is of the view that more or wider circulating local newspapers would be available in the borough if the council did not publish its own newspaper more frequently than quarterly.
"The reason is that if Hackney Today were produced on a quarterly basis, some of the advertising that it currently takes would potentially be available to other local media…and other markets would probably develop for alternative media…"
Powell then quotes from Citizen editor Keith Magnum's open letter to Hackney Mayor Philip Glanville, published last November, in which he argues the council's selling of advertising "has an adverse effect on local democracy".
Responding to the Town Hall's assertion that Hackney Today is a "cost effective means of communication", Powell said the local authority has "yet to make a wholly convincing argument as regards value for money".
Javid also dismissed the council's argument that quarterly publication would make it more difficult to communicate with hard to reach residents.
Powell said the Secretary of State's view was that "in addition to the internet, the council could use education centres, community centres and libraries as a means to communicate directly with Hackney's diverse population".
A spokesperson for Hackney Council said: "We haven't yet responded to the letter, and it wouldn't be appropriate to comment before we have done so."
DCLG's notice came a day after the council's Procurement Committee noted plans to award £1,382,000-worth of four-year contracts to pay for Hackney Today – £800,000 for printing costs and £582,000 for distribution – which are set to be approved in the coming weeks.
Last month, Mayor Philip Glanville defended the council freesheet at his Mayor's Question Time, saying: "Hackney Today is a rare thing, and it's a controversial thing for some, but actually having a council newspaper that goes to every door and promotes events like this isn't available to most councils."
You can read DCLG's letter to Hackney Council in full here.

subset: commoncrawl


text:
Hello Guomin,Guomin wrote: ↑July 25th, 2020, 5:57 pmGreetings, I just uploaded section 39:https://librivox.org/uploads/alg1001/anectodesofbigcats_39_wilson_128kb.mp3 Length: 03:09
Section 40:https://librivox.org/uploads/alg1001/anectodesofbigcats_40_wilson_128kb.mp3
Length: 03:16
In the audio, there's some weird noise from around 00:30 to 00:50 that occur only when I speak and when I try to clear it, the whole sound track is de-amplified; the biggest problem is that I am using the mic of the computer that is a good distance from my mouth, I have no idea why that happened Wish that doesn't compromise the quality of the recording too much.
Thank you,
I did listen to both 39 and 40 and heard immediately the sound difficulties you are describing, although your reading style is very nice.
Rather than go through the length of both files, I am going to suggest instead that you go ahead and rerecord both of these sections using a plug in mic. They are very inexpensive and make the sound SO MUCH BETTER! I know this because of my own recordings and believe me, the difference is night and day.
When you record, please keep in mind that we must not exceed 1 second at the start of the recording.
I look forward to hearing your "new" chapters.


text:
MLB 2019 Game #2: Mariners vs. White SoxChicago's third baseman Yoan Moncada applies a tag to Seattle's Tim Beckham during the seventh inning on Saturday afternoon.
This afternoon, the Chicago White Sox (3-4, .429) will close out the team's first home series of the 2019 season. Due to inclement weather, the White Sox moved Thursday's home opener against the Seattle Mariners (8-2, .800) to Friday. The White Sox won the opener, 10-8, then the Mariners hammered the Sox on Saturday, 9-2.
The Mariners, who opened the season early with two games against the Oakland Athletics in Japan's Tokyo Dome (and said goodbye to team legend Ichiro Suzuki), have been red hot. Seattle swept the two games in Japan, then won three of four against the defending World Series champion Boston Red Sox, and then swept a second 2-game series against the Los Angeles Angels.
Today, the Mariners will send 34-year-old Wade LeBlanc (1-0, 6.75 ERA) to the mound. During his lone appearance this season, he lasted 5 1/3 innings against the Red Sox. LeBlanc surrendered four earned runs (six total), but Seattle's offense provided enough firepower to give him the win.
Ivan Nova (0-0, 1.29 ERA), will answer for the White Sox. The 32-year-old righty pitched seven innings against the Cleveland Indians. He allowed one run, but the bullpen lost the lead costing Nova the win.
The season is young, but the Mariners maintain a 2 -game lead over the Texas Rangers in the American League West. In the American League Central, the White Sox sit two games off the pace. The Minnesota Twins and Detroit Tigers, both tied atop the division, hold a half-game lead over the Indians.
Photo: Nuccio DiNuzzo / MLB Photos


text:
Kelly & Joe recently got in touch with me and asked me to do some portrait photography for them in a place what was very special in their hearts. They chose to have their shoot in a beautiful Cotswold village called Winson which is just outside of Bibury. They travelled all the way up from Somerset specially for the shoot.
They had visited and stayed in the village a few months before and it was where they got engaged. Kelly & Joe also asked if they could bring their puppy with them to which I absolutely said YES!
Winson village consists of a church, village green and a few houses but there's a really lovely walk over the river and into the fields which gives a fantastic view over the whole village. It provided such a gorgeous backdrop to the shoot.
We spent half the shoot without pup and then it was time to release the hound!
If you're looking to have some portrait photography in the beautiful Cotswolds, please get in touch.


text:
LABS/R – our laboratory software for synthesis optimisation
Support for all stages in the production process
From research & development to technical centres
In any sector, research and production processes are often associated with a large number of experiment series, which include a vast array of raw materials, process steps, parameters, and examinations. These production processes and subsequent examinations of products require a great deal of work and time; are prone to error; often incomplete; and very difficult to imagine without IT support.
Use LABS/R to optimise the production process
As an integration platform, LABS/R for formula and synthesis optimisation, in combination with the LABS/Q® LIMS from the LABS Suite, allows all work processes to be fully supported from project development, planning and the implementation of experiments, to the examination of the manufactured products, through to evaluation.
How synthesis optimisation benefits you
Our LABS/R laboratory software can be used to manually restrict the number of experiments, or to do so supported by a statistical Design of Experiment. During fermentation, the experiments can be automatically transmitted to the machines or process control systems. The direct import of actual experiment results allows the production process for each individual experiment to be monitored and the results to be documented centrally. Because all information is stored in a central database, a variety of graphical and statistical evaluations can be performed and complex reports prepared and distributed. This enables seamless and faultless documentation and the straightforward re-use of your data, saving on both time and costs.
Design of experiment
Description of experiment series
Automatic handling of experiments
Recording of analytical and process-related results
Support with evaluation and reporting


text:
Program Requirements
Students are required to complete 8.0 credits as follows:
1. Courses at the A-level (1.5 credits)
VPMA95H3 Elementary Musicianship
1.0 credit in Performance (Students must choose the graded option for this credit)
2. Courses at the B-level (2.0 credits)
ACMB01H3 Critical Reading, Thinking and Writing for ACM Programs
VPMB01H3 Introduction to Community Music
VPMB82H3 Music in the Contemporary World
VPMB88H3 Materials of Music I
3. Courses at the C-level (0.5 credit)
VPMC88H3 Topics in Music and Culture
4. 4.0 additional credits in Music and Culture (VPM) courses, at least 1.5 of which must be at the C-level, and at least 0.5 of which must be at the D-level.
Students are encouraged to develop depth of learning through study in one or two of the areas of focus described in the Music and Culture Areas of Focus Table.
Students can count a maximum of 2.0 credits of Performance courses toward component 4 of the program completion requirements. Students who count Performance courses towards component 4 must choose the graded option.


text:
Lots of news and trailers are arriving before the E3 press conferences kick off this years onslaught of gaming news. Though EA Games E3 conference sneaks its way in. I'll be covering the gaming news of June 3 to 9, 2018 and please note I cover what I found interesting during the week.
Game Releases:
Totally Accurate Battlegrounds –
A battle royale last man standing game, with weird flippy floppy characters and a Gangsta mode. This comes as a sort of late April fools joke from developer Landfall. It has a wide variety of weapons to use and a crazy art style that sort of makes you grin. It was free for anyone on Steam for the first 100 or so hours after which it will cost 5 USD. It is a PC only game.
Gaming News:
Hitman is back to kill and kill again. A new game in the series titled, Hitman 2, has been announced and has a flurry of trailers to go with it to boot. Now gone from the series however is the episodic nature which they delivered mission. The game will be coming out later this year, November, 13 2018, with pre-orders getting access to Hitman Sniper Assassin.
It looks like another solid entry into the series though the trailer didn't show much actual game play so it is a bit hard to judge it. However, IO Interactive have always created solid Hitman games along with other games that are just fun to play. I feel like this is one of the few instances where I don't necessarily need to see what I'm getting myself into with game play.
Crackdown 3 which has been previously delayed to improve the game, has once again suffered another delay. This time the game is being moved to a February 2019 release date though one doubts it makes it to that date. Visit WindowsCentral.com for the complete story on the delay.
This is beginning to get the feeling of a cursed game that may never come out. Of course only time will tell, but one does get the whole Duke Nukem Forever vibes from this one. Hopefully it does come out and crush it, just right now it seems lost in a no man's land and can't get close to restarting or finishing what it started.
Valve has decided a hands off approach may be the best approach for what content is allowed onto the Steam digital store platform. The only exception being games that are considered "trolling", are in someway illegal, or fail to meet technical quality standards that Valve have set. This comes from a report via PCgamer.com who also believe this decision isn't the wisest of moves.
Oh boy. I get why this is happening but it ain't going to be pretty. Fans generally want well run stores that have some sort of control over the products so that they don't have to sift through to find the best products. Valve seems to be more intent of a free market ideal where everything hits the market and it is your own fault for buying whatever game you bought. It will be interesting to see how this plays out on the store front and if it effects sales of games or not.
Paradox Entertainment have bought another company, this time acquiring Harebrained Schemes. This developer has been responsible for the creation Shadowrun Returns, Shadowrun: Dragonfall, Shadowrun: Hong Kong, Necropolis, and BattleTech. The purchase price was 7.5 million USD plus some of Harebrained Schemes earnings over the next five years. Poygon has a full report on what to expect from this transaction.
This is a pretty straight forward acquisition after the two worked together on BattleTech. The companies share a vision and sometimes the best way to make that happen is sell a company to keep the dream going. The only worry is Paradox's love of DLC and how easily that can fracture a player base.
Abrams, no not the famous tank but rather the famous movie and television producer J.J. Abrams, and his company Bad Robot will soon be making video games. In order to do this they have teamed up with Chinese conglomerate Tencent to make both indie and AAA games for all platforms. This news comes from Techcrunch who have a great breakdown on who will be in what role.
Another deal that makes sense but also makes me a bit nervous, anytime a company becomes associated with Tencent it seems like things never turns out as well as they should. Maybe things will change this time, but aside from Riot Games League of Legends they haven't had much big success.
Rockstar has revealed the preorder bonuses for Read Dead Redemption 2. There are three editions to choose from, Standard which includes the game and some DLC, the Special Edition which includes some side missions that aren't vital to the story plus a map and some other DLC goodies. Then there is the Ultimate edition which includes all the previous content plus some extra weapons and a nice horse. Finally there is the collectors box which does not include the game but has lots of physical goodies like playing cards, a jigsaw puzzle, and a metal box. You can learn all about the preorder bonuses over on IGN.com.
Yeah this leaves me with the impression that Take-Two and Rockstar are going to milk there latest game for all the micro-transactions that they can. I don't blame them, but for me that means this will turn out into a pass until I see how they plan to continue to support the game. Also per me being an absolute nuisance, this game is titled as a sequel to the first game yet is really a prequel to Red Dead Redemption which makes no sense.
EA held its E3 conference with some nice surprises and generally what is expected from them. Aka Battlefield, Anthem, and Sports. Some of the surprises include Respawn's Star Wars Jedi Fallen Order which didn't get shown, Unravel 2, and the new original game Sea of Solitude.
Full Conference:
Some trailers of note:
This wasn't a great conference for EA. They showed games, but the showcase never really felt inspired. Part of that is there need to get through many games that it feels like nothing gets to much focus. That is aside from Anthem which they spent a fair amount of time explaining. The big win for me was Sea of Solitude which looks both lovely and creepy. I'm curious about the Jedi Fallen Order, Unravel 2, Battlefield V, and Anthem but those I want to see more of.
Entertainment News:
The Lego Movie 2: The Second Part got its first trailer, and well it returns to its silly nature with a bit of charm. This time an Alien has kidnapped many of the heroes from the first movie and taken them away to possibly save another world. However, Emmet isn't going to lay down while all his friends have been taken so he sets off to save the day. Starring Chris Pratt and Alison Brie the movie will be arriving in movie theaters on February 8, 2019.
This is a pretty charming little trailer it is very fun and sweet without going to deep into what the movie is about. My issue is that I kind of feel like the trailer was enough for me, I don't feel any need to see any more than what was in it. As the movie gets closer to its release date I may change my mind, but we will see.
Dragons are still in style and the charming movie series How to Train Your Dragon is getting a third movie which will be coming out on March 1, 2019. Titled, How to Train Your Dragon: The Hidden World, it brings back Toothless and Hiicup as Toothless finds love with another dragon and once again peace between dragons and people is threatened by a Dragon hunter.
Another charming trailer and with this one I'm a bit more curious to see it. I liked the first two movies and this makes me want to go back and re-watch them. This is one that I'll look forward to though I'll probably still wait to hear some reviews about it.
Well we began E3 with EA Games and what interesting things that they have going on, plus all the gaming news that squeaked its way in before the crush of actual E3 announcements. But for now I must end this post. Thank you so much for stopping by and taking a look around. For those that wish to contact me for questions, suggestions, or comments all of which I welcome you can do so through three difference ways. You can use the comment section below, you can find me and talk to me on Twitter at @Snipehockey, or you can email me at firstname.lastname@example.com.


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Program Description
USQ is offering up to 25% international student scholarships.
Read more about the scholarships offered below:
International Accommodation Scholarship
International Student Support Scholarship
International Student Support Nursing Scholarship
Learn to capture and transform Big Data
With constant advances in technology, internet speed, and social media, professionals are facing the challenge of capturing, storing, transferring and organizing large quantities of data. USQ's Bachelor of Information and Technology (Data Analytics) will equip you with cross-disciplinary skills to capture, process and interpret large volumes of data and communicate the valuable information to the intended audience.
You will explore computing, statistics, data mining, information systems, data management, sorting, and presentation, as well as problem-solving, project management, teamwork, communication, and ethics.
Apply your skills in our High-Performance Computing facility with cutting edge and industry-related technologies. Now is the time to take that first step into a career that will be dynamic, global and in demand.
Professional accreditation
USQ is currently seeking accreditation with the Australian Computer Society (ACS).
Career outcomes
With the explosion of data, data analytics professionals are in high demand. Graduates will be well-positioned to work as a data analyst, data scientist or data statistician in almost all job sectors including IT, public relations, retail, advertising, and banking.
Programme structure
Courses to be studied
- Core courses (8 units)
- plus 1 x major (8 units)
- plus second major
- or 2 x 4-unit minors
- or 1 x 4-unit plus 4 x approved courses (8 units)
How much will it cost?
Approximate annual costs for your first year of study (8 units) in this programme are:
Study Mode/ Cost
- Commonwealth supported: AUD 9,352
- Domestic full fee paying: AUD 20,000
Loan to help you pay your fees
You may not have to pay your course (subject) fees upfront. HECS-HELP and FEE-HELP allow you to defer your fees until your income reaches a certain level.
You may also be eligible to receive financial support from Centrelink.
Scholarships and financial assistance
You may be able to apply for scholarships to help with your study costs.
Entry Requirements
- Subject pre-requisite: English (4, SA) or equivalent
English Language Requirements
You are required to satisfy the applicable English language requirements. This programme requires a minimum of IELTS 6.0 or equivalent.
If you do not meet the English language requirements you may apply to study a University-approved English language programme.
Admission pathways
A number of other pathways are also available if you haven't been able to study previously or don't meet the requirements for entry into your programme of interest.
*Further admission information
An adjusted Selection Rank is a result of combining additional ranks through special entry schemes for admission.
Special entry schemes for admissions may help you get into the programme of your choice by increasing your Selection Rank, through the allocation of additional ranks in certain circumstances.
How to apply
Closing dates
Applying directly to USQ:
- Semester 3, 2020 - applications close Monday 5 November, with semester 3 commencing on Monday 19 November 2020.
- Semester 1, 2021 - applications close Monday 18 February, with semester 1 commencing on Monday 25 February 2021.
- Semester 2, 2021 - applications close Monday 1 July, with semester 2 commencing on Monday 15 July 2021.
If you are applying via QTAC, you will need to check the QTAC closing dates.
Credit for previous study or work experience
You may be eligible for credit if you have previously studied or had relevant work experience. This will help to reduce the number of courses that you need to study to finish your programme.
About the School
Are you thinking about studying in Australia? The University of Southern Queensland (USQ) prides itself on providing the best support possible to help you reach your study and career goals. USQ studen ... Read More


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The beauty of working out on a treadmill from the comfort of your own home is not only convenient, but it can also save you a great deal of money. Paying a gym a monthly fee can end up costing thousands per year which can put a damper on your budget.
When you invest in the best manual treadmill on the market, you are saving yourself some money as well as giving yourself quite a gift. It can be a challenge to fit in time to go to the gym when you are working full time, taking care of your family, and participating in social activities.
Because of this, when you invest in the best rated manual treadmill, you can workout from the comfort of your own home whenever it fits into your daily routine. One of the best perks of working out at home means that you don't have to worry about gym hours or to get to a fitness class before it fills up.
So, what is the best manual treadmill? There are many great options to choose from, but there are some things to keep in mind while you conduct your research on the best manual treadmill.
1. Not all treadmills are conducive to all fitness levels. If you are an enthusiastic runner, you will want to find a treadmill that can keep up with your endurance, stamina, and speed. By searching for the best manual treadmill for jogging, you are sure to find something that is going to fit your goals and fitness lifestyle.
2. A treadmill doesn't have to be heavy and get in the way of your family life. In fact, many great treadmills are portable and can be folded up and stored while not in use. The best portable manual treadmill will be easy to move with durable wheels and will also be easy to fold up and put away.
3. There is a treadmill to fit your lifestyle. Whether you are a child, teenager, adult, or even a senior citizen, there is a treadmill that will work for you! In fact, the best manual treadmill for seniors offer features that are conducive to that specific target market. For example, a treadmill built specifically for seniors will provide additional safety features as well as extra cushioning on the walking platform.
4. A treadmill that is made especially for walking may not be conducive to those who have the desire to run. The best manual treadmill for walking may have a lower maximum speed and less horsepower than the best manual treadmill for running. That is why it is essential to research the treadmill you will commit to buying as your fitness companion. You do not want to end up with a great walking treadmill when you are a runner. You will end up being disappointed in the lack of speed and ability for the machine to keep up with your endurance level. Running takes more endurance and stamina than most walking which means you need a device created explicitly with a runner in mind.
Best Manual Treadmill
Lifespan TR1200 Under Desk Treadmill
The Lifespan TR1200 Treadmill is perfect for someone who works an 8-hour day sitting at their desk. Research has indicated that sitting is now the new smoking epidemic as it is causing many to live a sedentary lifestyle which often results in weight gain and cardiovascular problems.
To mitigate sitting for 8 hours a day, many are investing in an under the desk treadmill such as the Lifespan TR1200. Small, compact, and ready to use right out of the box, this treadmill is sturdy and has a maximum user weight of 300 pounds. With a generous warranty package, this treadmill is a significant investment that could save your life!
Pros and Cons
- Great for those who sit at a desk all day
- Small and compact
- Fully assembled out of the box
- Max user weight is 300 pounds
- Lifetime warranty on frame, 3-year warranty motor, 2-years parts, 1-year labor
- Not eligible for international shipping
- Does not offer Bluetooth compatibility like other models
Exerpeutic TF1000 Ultra High Capacity Electric Walking Treadmill
The Exerpeutic TF1000 Treadmill is ideal for those who want an efficient machine that is made for walkers. It is important to note that this treadmill offers a motor that is limited to 1.5 horsepower. Where most treadmills on the market only support those who are around 220 pounds, this treadmill is quite rare in that it can help a person who weighs up to 400 pounds.
Made with high-quality components, the manufacturer provides a 5-year motor warranty and 1-year frame warranty. It is essential to note that this treadmill is not conducive to those who prefer to run on a regular basis.
Pros and Cons
- Great for walkers
- Offers 1.5 horsepower motor
- Supports up to 400 pounds
- 5-year motor warranty, 1-year frame warranty
- May not be eligible for international shipping
- Not conducive to runners
Assault Air Runner Treadmill
The Assault Air Runner Treadmill is not like any other on the market. If you hate to run on a treadmill and prefer to run outdoors, this treadmill is one that you should seriously consider. The reason is that this treadmill makes it feel as if you are running on air and is indeed a unique and exhilarating experience.
Research has also indicated that this machine is proven to produce 30% more calorie burn than a standard treadmill. With a 150,000-mile belt life, this treadmill does not use any electricity and is an entirely sustainable option.
There are many great perks to this treadmill but it is important to note that it does come with expert assembly and the maximum user weight is unknown.
Pros and Cons
- Expert assembly included
- Feels like running on air
- Burns up to 30% more calories
- 150,000-mile belt life
- Sustainable and uses no electricity
- Not eligible for international shipping
- Max user weight is unknown
Sunny Health and Fitness SF-T7603 Treadmill
Sunny Health is a company that is well known for manufacturing high-quality treadmills that can withstand the test of time. The SF-T7603 model offers a 2.2 horsepower motor as well as nine built-in fitness programs which makes it easy to get fit.
With a generous surface space and a motor that produces speeds up to 9 miles per hour, this treadmill is excellent for avid and novice runners alike. While this treadmill has many great qualities, it is important to note that it cannot accommodate individuals over 220 pounds.
Pros and Cons
- 2.2 horsepower motor
- Generous 16x49 inch surface
- Nine built-in user programs
- Speed up to 9 mph
- Not eligible for international shipping
- Only suitable for people up to 220 pounds
Redmon Fitness Treadmill for Kids
Treadmills aren't just for adults! In fact, many are beginning to invest in a treadmill for their kids, such as this Redmon Fitness model. The reason for this is that many kids are finding themselves sitting and watching a tablet more often than creatively playing with toys and using their imagination.
Investing in an affordable treadmill for your child will provide the opportunity for them to be active while they enjoy their favorite kid's programming. Great for children between the ages of 3 and 6, this treadmill is easy to assemble and only needs 2 AA batteries to operate. With additional safety features, this treadmill is ideal for children, not adults.
Pros and Cons
- Non-motorized and safe for kids
- Easy to assemble-tools included
- Only needs 2 AA batteries to operate the motor
- Great for ages 3-6
- Safe and reliable
- Limited shipping out of the USA
- Not recommended for an adult
Merax JK1603E Electric Treadmill
If you are looking for a treadmill that will not cause you stress in setting it up, the Merax JK1603E offers easy set-up right out of the box. The easy to read multi-function display showcases one's speed, distance, time, and calories.
The convenient size and quiet motor noise make this treadmill perfect for those looking for a machine that is easy to use and set-up. While it only provides standard incline functionality, many raves about this treadmill as it can provide consistent workouts for years to come.
Pros and Cons
- Easy assembly
- Multi-function display
- Convenient size
- Low noise motor
- Not eligible for international shipping
- Manual Incline
Confidence Fitness Magnetic Treadmill
The Confidence Fitness Magnetic Treadmill offers a quiet and smooth user experience which is great for those who live in a small space and do not want to disturb fellow neighbors, roommates, or family members.
Suitable for those up to 220 pounds, this treadmill comes with a 12-month warranty and is foldable and easy to store when not in use. It is important to note that the running surface could be a bit wider but if you are looking for a treadmill for a narrow and small space, this will do just fine.
Pros and Cons
- 12-month warranty
- Suitable for those up to 220 pounds
- Multi-function screen
- Quiet and smooth user experience
- Foldable and easy to store when not in use
- May not be eligible for international shipping
- Running surface could be wider
ZAAP TX1000 Motorized Electric Treadmill
This motorized treadmill by ZAAP is convenient as it folds up and is quickly put away while not in use. Perfect for small apartments, this treadmill offers a multi-function display that showcases speed, distance, calories, and elapsed time. The 12 built-in fitness programs make working out on a daily basis a fun experience that you will not tire of.
It is important to note that this treadmill has a max peak speed of 6 miles per hour and it is unclear as to how much weight it can accommodate.
Pros and Cons
- Max speed of 6 mph
- Foldable for easy storage
- Includes 12 built-in fitness programs
- Multi-function LCD display
- May not be eligible for international shipping
- Max user weight is unknown
EFITMENT Adjustable Incline Treadmill
Offering a generous running surface and an easy to read LCD monitor display, the EFITMENT Adjustable Treadmill is durable, heavy, and is made with high-quality components. The LCD monitor makes it easy to keep track of your progress as it displays speed, distance, time, and calories burned.
This treadmill offers excellent all-around convenience, from the hand pulse sensors that make keeping track of your biometric statistics hassle-free to the foldable frame that makes it easy to store when not in use.
Pros and Cons
- Generous running surface
- LCD monitor displays speed, distance, time, calories
- Hand pulse sensors for biometric screenings
- Easy fold up storage
- Heavy
- May not be eligible for international shipping
- Manual Incline
Binxin Folding Electric Treadmill
Last but certainly not least, the Binxin Folding Electric Treadmill is unique in that it is portable, offers a built-in heart rate monitor, special safety functions, and an easy to read multi-function LCD display. The display provides information such as speed, distance, time, and calories burned.
It is important to note that this machine has a max user weight of 220 pounds and the warranty information could not be found at the time of publication.
Pros and Cons
- Multi-function LCD display
- Safety function
- Heart rate monitor
- Portable
- Max user weight of 220 pounds
- May not be eligible for international shipping
- Warranty information is unknown
Final Thoughts
Searching for the perfect manual treadmill does not have to be a taxing process. This guide outlines a variety of manual treadmill options ranging from portable to machines that are made explicitly for various lifestyles.
With affordable pricing, generous warranty coverage, and free shipping, investing in a treadmill is a smart and healthy decision.


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Canada's top emerging technology company, Shopify Inc., continues to outperform expectations, reporting 2016 results Wednesday and introducing 2017 financial forecasts that were well ahead of analyst targets.
The Ottawa company's stock rose by more than eight per cent and has now gained more than 250 per cent since it went public in May 2015 at $17 a share.
"I think the company is in really, really, really good shape right now," chief executive and co-founder Tobi Lutke said on a conference call with analysts.
Shopify, which provides a cloud-based online software platform used primarily by small and medium-sized retailers to manage their e-commerce and bricks and mortar operations, booked revenue of $130.4-million (U.S.) in the fourth quarter, an increase of 86 per cent over the same period a year earlier. That exceeded average analyst forecasts of $121.7-million as well as the guidance Shopify had provided to the Street.
The company also posted a $9.3-million operating loss, up from $6.5-million in the fourth quarter of 2015. But analysts were watching for the "adjusted operating loss," which amounted to $0.8-million, well below expectations. The company posted a quarterly net loss of $8.9-million, or 10 cents per share.
The fourth quarter is Shopify's busiest, encompassing the holiday shopping season. Shopify ended the year with 377,500 merchants using its platform, up by more than 50,000 since Sept 30, and said merchants on average increased the value of merchandise sold through the platform in 2016 by 25 per cent year over year
The company also said it expected revenue in 2017 to range between $580-million and $600-million, ahead of average analyst expectations of $562-million. That would represent a 49 per cent-plus increase over the company's $389.3-million revenue for 2016. Revenues are expected to be $120 million in the first quarter, up 65 per cent year over year.
"Shopify delivered an exemplary quarter and revenue growth outlook, Canaccord Genuity analyst Richard Davis wrote in a note. "Given the high probability that Shopify will execute well this year and beyond, there should be plenty of growth investors waiting in line to buy this stock"
Shopify management reiterated its earlier goal to exit 2017 running its business in the black on an operating profit basis. But analysts questioned on a conference call why it forecast a full-year operating loss of $73 million and $77 million, double last year's level.
Senior management responded the company would be continuing to invest in expanding the company's offerings to merchants. Last year, Shopify has launched retail channels on Facebook Messenger and Amazon, expanded its shipping services, retooled its mobile app and launched a merchant financing division, which provided $35 million in cash advances to customers in the fourth quarter. Shopify also more than doubled the number of larger customers using its "Shopify Plus" offering to 2,500, adding such brands in the fourth quarter as Moet Hennessy and the Wall Street Journal.
"We're in a very strong position," chief financial officer Russ Jones said. "We just think investing for the long term is the right thing to do."
Citi Research analyst Ken Wong wrote in a research note: "The strong quarter and guid[ance] should be enough for [the fourth-quarter results] to be viewed positively" and lead the stock price "to trend higher."
Despite opposition and a threatened boycott from some merchants and customers to the fact Shopify hosts the online store of alt-right publication Breitbart News, there was no evidence of any impact on its results, and analysts asked no questions pertaining to the matter.


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Tech moves fast! Stay ahead of the curve with Techopedia!
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Linux Containers (LXC) is a type of virtualization setup that works with virtual containers created at the operating system level. This innovative type of virtualization allows for sharing resources like CPU and memory, without actually creating virtual machines. Linux Containers supports isolated namespaces and shows users various views of the operating system environment.
Container-based virtualization has emerged as an alternative to traditional hypervisor virtualization, where a central resource manages various partitioned and designated virtual machines with their own CPU and memory allocations. By contrast, in a container environment, instead of setting up virtual machines, the system sets up resources for each container and delivers them directly from the operating system, which, in the case of LXC, is the kernel. Other container setups include Docker and CoreOS.
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H.R.6346 - To extend certain trade preference programs, to authorize the extension of nondiscriminatory treatment (normal trade relations treatment) to the products of Vietnam, to modify temporarily certain rates of duty and make other technical amendments to the trade laws, and for other purposes.109th Congress (2005-2006)
BillHide Overview
|Rep. Thomas, William M. [R-CA-22] (Introduced 12/05/2006)
|House - Ways and Means
|Latest Action:
|House - 12/05/2006 Rules Committee Resolution H. Res. 1092 Reported to House. Rule provides for consideration of H.R. 6346 with 1 hour of general debate. Previous question shall be considered as ordered without intervening motions except motion to recommit. Measure will be considered read. Bill is closed to amendments. (All Actions)
This bill has the status Introduced
Here are the steps for Status of Legislation:
- Introduced
Subject — Policy Area:
- Foreign Trade and International Finance
- View subjects
Summary: H.R.6346 — 109th Congress (2005-2006)All Information (Except Text)
There is one summary for H.R.6346. Bill summaries are authored by CRS.
Shown Here:
Introduced in House (12/05/2006)
Africa Investment Incentive Act of 2006 - Amends the African Growth and Opportunity Act (AGOA) to extend duty-free treatment to specified imported sub-Saharan African apparel articles. Extends the AGOA through 2015.
Amends the Internal Revenue Code to allow a tax credit against foreign income earned by U.S. companies doing business in sub-Saharan Africa.
Amends the Trade Act of 1974 with respect to limitations on waivers of competitive need under the Generalized System of Preferences (GSP) Program. Extends the GSP Program.
Haitian Hemispheric Opportunity through Partnership Encouragement Act of 2006 - Amends the Caribbean Basin Economic Recovery Act to provide duty-free treatment for specified Haitian apparel articles.
Andean Bridge to a Reciprocal Trade Partnership Act - Amends the Andean Trade Preference Act to extend duty-free treatment and other preferential treatment to articles imported from Bolivia, Ecuador, Colombia, and Peru.
Authorizes the President to extend nondiscriminatory treatment (normal trade relations treatment) to the products of Vietnam.
Miscellaneous Trade and Technical Corrections Act of 2006 - Amends the Harmonized Tariff Schedule of the United States to repeal certain expired provisions reducing temporarily the rate of duty on specified chemicals.
Provides, through December 31, 2009, for new duty suspensions and reductions and existing duty suspensions and reductions.
Amends the Tariff Act of 1930 to provide for certain reliquidations.
Establishes the Pima Cotton Trust Fund.


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|Research type
|Post-Doctoral Advanced Research Institute
Field of research
|All areas of Science
|Prof. José Manuel Martínez Sierra
|26 Trowbridge
|Cambridge, Massachusetts, 02138
|Harvard University
Complutense University
The Real Colegio Complutense at Harvard University (Cambridge, Massachusetts):[1] The RCC at Harvard is an academic institution aimed at providing intellectual exchange between Harvard and the Spanish Academia. It is located at 26, Trowbridge Street, Cambridge (MA).
The RCC was founded as a joint cooperative institution to foster intellectual and scientific interaction between Harvard University and the Universidad Complutense de Madrid, with the support of HM King Juan Carlos I, HM Queen Sofia of Spain and the Commonwealth of Massachusetts. It follows the tradition of the Royal Spanish College, founded in 1364 to host Spanish Visiting Scholars at the University of Bologna. In November 1990, the Dean of the Universidad Complutense de Madrid at the time and the then-president of Harvard, Derek Curtis Bok, signed an alliance to create the Real Colegio Complutense. The King of Spain inaugurated the building in 1993 and the agreement was extended in 2009. RCC is currently celebrating its 25th anniversary.
The RCC accord is the only one of its sort ever to have been approved by Harvard. The institution is directed jointly by the President of Harvard and the Rector of Complutense University. The RCC academic and advisory councils include outstanding members from both universities. Recently, the RCC has incorporated three new Partner Universities, which are the Universidad Politécnica de Madrid, Universidad Rey Juan Carlos, Universidad de Alcalá de Henares and Universidad de Sevilla, each of them represented by official delegates.
The current director is Prof. José Manuel Martínez Sierra, Jean Monnet ad personam[2] Professor for the Study of European Union Law and Government. He is Faculty Affiliated of the Minda de Gunzburg Center for European Studies at Harvard and Faculty Associate of the David Rockefeller Center for Latin American Studies. He is also a Member of the IGLP Advisory Council at Harvard Law School.
Every year, the RCC offers Research Grants to a select number of Spanish scholars who conduct their research at Harvard as Visiting Scholars. It also offers a number of Graduate Fellowships to Spanish students who attend the different Graduate Schools at Harvard. In addition to this, faculty and researchers from the Partner Universities and other affiliated centers are eligible to becomeRCC Fellows, enjoying the same privileges as Harvard's non-tenured Faculty.
The RCC sponsors a number of Research Projects and Programs that cross over different fields of study, including Experimental and Social Sciences, Architecture, Health, Engineering, Education, Communication and Humanities. The relevance of RCC Fellows, Associates and Alumni/ae, as well as their partnerships with local scholars and the Faculty of Harvard University, allow these projects to generate international knowledge networks and to promote intellectual exchange in a multidisciplinary framework.
As part of this framework, the institution hosts academic lectures and scientific events for an open audience, including Harvard professors and students.
The RCC has signed several agreements with Spanish and International Institutions to organize summer seminars and workshops at the center. These institutions include the ISDI (Instituto Superior para el Desarrollo de Internet), the Fundación Rafael del Pino, the International Academic Program of the Universidad Autónoma de Madrid and the Centro de Investigaciones Sociológicas.
- ^ "Real Colegio Complutense at Harvard". rcc.harvard.edu. Retrieved 29 October 2014.
- ^ "Jean Monnet Program".
External links
|Wikimedia Commons has media related to Real Colegio Complutense.
- RCC Website
- Harvard University
- Universidad Complutense de Madrid
- Universidad Politécnica de Madrid
- Universidad Rey Juan Carlos
- Universidad de Alcalá
- Universidad de Sevilla


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The most popular daily soap Yeh Hai Mohabbatein is all set to show another major twist in the storyline.As per the current track, Ruhi (Aditi Bhatia) is against Raman (Karan Patel) as she trusts Nikhil.Raman is getting irked with Ruhi & Nikhil's love affair…
therefore he confronts Shagun and seeks her help in separating Nikhil and Ruhi.
As we all are well aware of Shagun's character and her evilness having no limit.
Shagun traps Nikhil with a girl where suddenly Ruhi comes and gets shocked seeing Nikhil's intimacy with a girl.
Ruhi's anger bursts and she slaps Nikhil unfolding another major drama…and tags him characterless and cheater.
Will Ruhi come to know Nikhil's innocence..??
Keep Reading For More Updates Of Star Plus Show Yeh Hai Mohabbtein
That's How Shagun and Raman Will Trap Nikhil In Star Plus show Yeh Hai Mohabbtein Reviewed by Unknown on September 28, 2017 Rating:


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What Is CBD?
CBD, short for cannabidiol, is one of over 100 cannabinoids found in cannabis plants. Cannabinoids (including CBD, THC, and many others) are chemical compounds that act on the receptors in your body's endocannabinoid system (ECS).
CBD is the most abundant cannabinoid in cannabis plants and is being researched for its ability to help those suffering from anxiety, arthritis, epilepsy, and various other conditions. CBD is legal in much of the United States and is being used by many to promote general wellness and to combat anxiety, stress, sleeplessness, inflammation, and more.
Where Does CBD Come From?
CBD comes from the cannabis plant, and that's where the confusion begins for a lot of people.
Cannabis is a family of plants containing multiple species including marijuana and hemp. While similar, these plants have one major difference, and that's the amount of THC (tetrahydrocannabinol) present. THC is mostly known for its ability to cause psychoactive effects in users. Hemp contains less than or about 0.3% THC (i.e., the legal limit). Marijuana, however, contains much more.
For this reason, it's common for CBD products to be derived from hemp, not marijuana.
How Does CBD work?
Without getting into the technical details, understanding the science behind CBD requires a brief overview of the endocannabinoid system (ECS).
Back in the 1990s, researchers found that there were receptors in animal brains that were extremely sensitive to THC, which kick-started a massive biological breakthrough. It turned out that our bodies naturally produce similar chemicals, called endogenous cannabinoids (i.e., cannabinoids from outside the body) or "endocannabinoids," which gives the system its name.
The ECS regulates several essential processes in the body with its receptors, and the most important of these are called CB1 and CB2.
CB1 & CB2 Receptors
CB1 receptors are mostly found in the brain and are intensely compatible with THC. Tiredness, mood, appetite, and pain are all affected by the CB1 receptors. CB2 receptors, on the other hand, are spread throughout the body. These largely influence skin health and inflammation.
Effects of CBD in the Body
Whereas most chemicals directly influence the body's processes, CBD can make your body better at doing its job. CBD doesn't bind to either CB1 or CB2, but it can maximize the effects of the endocannabinoids your body naturally produces. For example, CBD inhibits the enzyme that breaks down anandamide, which reduces pain and boosts happiness. Science still has a long way to go with CBD, but it's promising. The FDA has approved two epilepsy medications derived from this chemical, so research around the benefits of CBD continues.
Frequently Asked Questions About CBD
Is CBD legal?
Check your state laws to see if CBD is legal where you live. In most cases, if the CBD oil has less than 0.3% THC in it, then it should be acceptable to use.
Can CBD get you high?
No, CBD can't get you high. THC is the chemical responsible for the "high" associated with marijuana. In fact, CBD actually makes THC less effective.
What's the difference between CBD and THC?
There are several differences, which are better explained in this guide to CBD vs THC.
Will CBD show up on a drug test?
No, CBD itself won't cause you to fail a drug test. Full spectrum CBD oils do contain trace amounts of THC, but it shouldn't be enough to test positively. That said, if taking high enough doses of CBD products containing THC, it is possible for THC to show up in a drug test. If you're still concerned, use 100% THC-free products.
Is CBD addictive?
No, CBD isn't chemically addictive. But like anything, it can become a habit.
What's the proper CBD dosage?
That depends on a multitude of factors, such as your weight and the type of CBD product you're using. It's best to start with the recommended dose listed on the product you purchase, and adjust as you learn how CBD effects you.
Where can I buy CBD products?
With Frontier Jackson! We offer everything from CBD oils and edibles to CBD topicals and pet products. We strive to provide high-quality, all-natural CBD products that promote a balanced and healthy lifestyle. Search our CBD products now.
New to CBD? Try This.
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Heritage Action Zone for Buxton Announced!
In May 2019, Historic England launched a new £95m fund to champion and revive historic high streets through the High Streets Heritage Action Zones as part of the Government's Future High Streets Fund initiative.
This scheme will provide support for historic high streets and the communities who use them so they can adapt to the challenges they face. Working with local councils and communities, Historic England will deliver physical improvements and cultural activities to regenerate these high streets and restore local historic character. This revival will become the catalyst for wider regeneration, with heritage and local character at its heart.
The Council's intitial Expression of Interest to develop a Heritage Action Zone in Buxton has been approved and will compliment the Future High Street Fund application heritage elements of the town centre.
The positioning of Buxton as a leading spa town and centre of wellbeing is crucial to its future development.The town has been an exemplar of heritage-led regeneration focusing on; its historic parks, the Crescent and spa buildings, the former Devonshire Royal Hospital, Opera House and the Market Place)
The current retail environment of Spring Gardens does not reflect the high heritage value present elsewhere in the town and meet the expectations of a premier historic destination. It does not offer the variety and experiences that modern visitors want. Without intervention, the recent closure of banks and national retailers will further acerbate its decline.
The ambition of the council, community and partners is to make Spring Gardens part of the visitor experience by exploiting the high heritage value of the environment. This creates an exemplar, distinct and unique backdrop to generate;
- New cultural experiences
- High quality retail, food and drink establishments
- Enhanced public realm
- Night time economy and town centre living.
A number of these themes are reflected in the Future High Street Fund bid for Buxton. In order to complement this the HAZ would focus upon the following themes:
- Production of a suite of guidance leaflets regarding traditional shopfront and signage.
- Explore the restoration and continuation of the missing colonnade around the Cavendish Arcade
- Repair and conversion of vacant listed buildings.
- Repair and restore the external façade of upper floors
- Heritage interpretation at key visitor entrance points
- Offer a complementary face lift scheme to allocate small grants towards modern units to improve colour scheme and signage
- Fund and deliver an education pack for school children.
Over the coming months the Council will be working with Historic England to put together a detailed delivery plan to enable the HAZ to commence in April 2020.
Contact Regeneration Team for further information.


text:
Photo Credit: http://www.fleamarketgardening.org/2014/05/05/garage-sale-shopping-101/
Every weekend, there's one constant as I drive around town... garage sale signs. I shouldn't care much about them as I rarely find interest in going, but when I see a sign written with a dinky ballpoint pen on cardboard in small text, I cry on the inside. And so, I want to go over a few things that garage sale signs teach us about the importance of design basics.
Your Audience
Let's assume this is a one-person garage sale shopper. This person is:
- Responsible for driving safely around others (hopefully)
- Driving fast (within the means of the speed limit, hopefully)
- Has a very small window of time to locate, analyze, and process the information seen on your sign (while staying on the road... hopefully)
- Really interested in making it to your garage sale ASAP
Your sign is this shopper's only hope.
This person has nobody else helping figure out where the garage sale is located. Your sign needs to convey a lot of information in less than a second. Your purpose and the shopper's needs should align to ideally benefit both parties. How can we do that?
The content should have purpose and intent. Think back to your audience's needs. They're driving fast and have a very small amount of time to process information. In the case of garage signs, they need pertinent information such as:
- Am I following a garage sale sign?
- Where should I turn next?
- When is this sale happening?
In the case of following a garage sale sign, there needs to be...
Because as more and more signs appear, it's important the driver continues to say "yes" to:
- Am I following the signs for the same garage sale?
Keeping the same colors, font, location of content, and wording for all signs will help. But consistency will only get us so far if the driver can't read your sign.
Contrast and Text Size
Where readability is concerned, contrast is the PB to text size's J.
The dinky ballpoint pen should be substituted for a thick, fat Sharpie®. Big, bold letters. While street signs are pretty stale, there are very rare occasions where I can't process the street sign. Take a cue from standard street signs for your garage sale sign. Big text improves readability.
In addition, when looking at materials for your sign, consider a white or highlighter yellow/pink background rather than a cardboard box. Brown on black is going to be harder to read than a white sign with black writing. This is coming down to contrast. Higher contrasts make text more readable, therefore making it easier for drivers to read your sign. My personal favorite signs have highlighter pink with black text. It's eye-catching and good on contrast.
Outside the Box
There's one item that always grabs my attention and if I could give out points for effort, I would.
Balloons have been a fantastic way to grab my attention and immediately process that I am following the same garage sale signs. There's the occasional blockage of information; however, they are so effective that I can overlook some of their weakness in displaying information easily.
...did you seriously talk about garage sale signs this long?
Yes. Yes I did.
Because good design exists everywhere, even in these weekend signs we encounter. Maybe we ignore them most days, but when we have a goal to find a great deal at a garage sale, these signs matter. Hopefully, the next time you are working on a project, consider the basics of design.
Read more of Nicole's blog posts on web design and usability:


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text:
(written from a Production point of view)
Peter Allan Fields (12 May 1935 – 19 June 2019; age 84) was a writer of many Star Trek: The Next Generation and Star Trek: Deep Space Nine episodes. He was also executive script consultant on Next Generation during the latter half of the fifth ("The First Duty" – "Time's Arrow") and during the sixth season. He then became a co-producer on Deep Space Nine during its first season and producer for its second season. Field contributed to three DS9 episodes after he left the writing staff. Showrunner Ira Steven Behr has credited Fields for the introduction of the Elim Garak character. (What We Left Behind)
Fields was interviewed by Terry J. Erdmann in the Star Trek: Deep Space Nine Companion and by Bill Florence for the article "Peter Allan Fields – Man of "The Inner Light", published in The Official Star Trek: The Next Generation Magazine issue 21, pp. 22-25.
Before Star Trek and following his career as a lawyer, Fields wrote several episodes for The Man from U.N.C.L.E., the show Deep Space Nine did a homage to with Del Floria's Tailor Shop on Deep Space 9's Promenade. Later, Fields was as an associate producer and writer on McCloud, an NBC series starring Diana Muldaur. Soon afterwards, he became a writer and executive story consultant for the popular ABC series The Six Million Dollar Man.
In addition to his work on Deep Space Nine, Fields worked with DS9 co-creator Michael Piller on the latter's short-lived UPN series, Legend (1995, starring John de Lancie). Other television shows for which Fields wrote include Knight Rider (1986), Jake and the Fatman (1988), and Xena: Warrior Princess (1995-1996).
Star Trek credits
- "Half a Life" (teleplay, story with Ted Roberts)
- "Cost of Living"
- "The Inner Light" (teleplay with Morgan Gendel)
- "Dax" (teleplay with D.C. Fontana, story)
- "Progress"
- "Duet" (teleplay)
- "The Circle"
- "Necessary Evil"
- "Blood Oath"
- "Crossover" (teleplay with Michael Piller, story)
- "For the Uniform"
- "In the Pale Moonlight" (story)
- "The Dogs of War" (story)
Star Trek award
Peter Allan Fields has received the following award:
- Hugo Award
- 1993 Hugo Award in the category "Best Dramatic Presentation" as Teleplay Writer for the episode "The Inner Light", shared with Morgan Gendel and Peter Lauritson
External links
- Peter Allan Fields at Wikipedia
- Peter Allan Fields at the Internet Movie Database
- Remembering TNG & DS9 Writer, Peter Allan Fields at StarTrek.com, the official Star Trek website


text:
A Little Bit MORE About Us!
Description: Kenny and Elle share their stories and how they got involved in youth ministry. Links: Grow Youth Ministry Curriculum We Need Your Help: Did you like what you heard? Please help us out by taking a few seconds to rate and review our podcast on iTunes. It really will go a long way to help us spread this tool to Kids min workers all over the world.Click Here To Rate And...Read More


text:
1or annoying. Really depends!
Did you ever watch Friends and laughed — so hard, that you couldn't really stop anymore? If this series taught me one thing then it's definitely "I'll be there for you". Might seem a little romantic and overwhelming(1) but that is actually how I feel about working on a project: I'm there, 100%.
I believe in the good. Good people, good products, good design. Since I can think I wanted to be a graphic designer. Today I'm so proud and honored to make a living from my passion.
A dear friend of mine asked me once if design could change the entire world. Not sure about this, but: It definitely changed mine.
I'm always up for new challenges. My goal for 2020: Clients who become friends or collaborators. Because I don't want to work for them – but with them. To a more sustainable, environmental-friendly, socially or emotionally meaningful year, filled with topics that I'm allowed to visualize. So looking forward!
I'm Fran. German Graphic Designer, Illustrator & Art Director with a Mexican heart. Based in Berlin since late 2018. Besides I lived and worked in Mexico-City and Kuala Lumpur.
Ideas and excited about it?
If you can't sleep
Brands & Clients
Marou Chocolate, Gracias a Dios Mezcal, Satom Organic Farm, Black Ivory Coffee, WWF, Deutsche Aidshilfe, Brot für die Welt, Kokeshi CDMX, Rokai Ramen, Rötter, Dante, Sombra Del Agua, Trade Rebublic, Metronom, Chanel, Hugo Boss, Görtz, Street One, Esprit, BODYART, Billy Boy, La Metropolitana, Subtropen Brand New Worlds GmbH, Creo-media GmbH, Prettysucks, Ablüh clothing, PRINZ Hannover
Abierto Mexicano De Diseño, Mexico-City, 2017
Vitrina, Mexico-City, 2017
Campamento De Diseño, Guadalajara, 2017
Collecteral, Kuala Lumpur, 2016
Schnittmenge, Hannover, 2015
Design made in Germany


text:
A Dark Day.
What a great night the old Count had had,
There's something awfully good about being bad,
On her side the poor pure pallid virgin lay,
Well… she had been unsullied yesterday.
How had she fallen for this old mountebank?
Had he spiked the drinks she drank?
That sly old dog had pulled out all the tricks
Once she'd removed purity ring and crucifix.
Towards well earned sleep he began to sink,
Daybreak came, revealing her in the pink ,
Then light disturbed his slumber and he awoke-
And the new day and his waters broke.
For it dawned on him, he had overslept
And from a deeply satisfied sleep he leapt,
He snatched frenziedly at the flimsy curtain-
Drac's no morning person, that's for certain.
For to be up and awake at daybreak
Could prove to be a grave mistake,
This was the finest sunrise Dracula had seen
Since contracting morning sickness back in 1517.
It's a cruel cruel world every soul must learn
And Drac's old poor pupils began to burn,
With mounting fear the Count was gripped,
Then mortal terror as the curtain ripped.
Clear and bright the sun was shining,
No black clouds, no silver lining,
How the old roue rued his dinner date
But Dracula's last regret was- too late.
When Drac was 'entertaining' some fair maid
Ironically a 'Do Not Enter' sign was displayed,
Behind the door, snoring in sweet surrender
One lay, young and slender, neck slightly tender.
Now Igor, Count Dracula's idiot servant
Was slow and simple but not unobservant,
Igor was charged with Castle Housekeeping
And assumed Drac was somewhere sleeping.
Dracula had long been bit of a rover,
Igor thought he must be sleeping over,
And Igor decided, while the bat's away
He wouldn't bust his hump today.
It was only as the dark shadows crept in
Igor returned and conscientiously swept in,
As usual, the Counts bier was a bloody mess,
No Count, only a comatose damsel in distress.
The Counts chamber left Igor disgusted,
Just last week he'd had it done and dusted,
Now he'd gone off, but left behind a filthy cleaner
Wondering if White Spirit might shift this patina?
Igor took a dark look around the room,
Then, teeth gritted, started pushing broom,
Last weeks hard work looked hardly worthwhile-
Though by the window he saw he'd missed a wee pile.
Since the dirty Count was beyond caring
He'd give the Castle a damned good airing,
Boy, that backwoods bumpkin went to town,
Igor even turned the belfry upside down.
He transformed a last resort for the unwary
Into a sun-drenched dream home, light and airy,
He made a cold creepy Castle into a keeper
Unless the prospective buyer dug a little deeper.
But since Drac has gone to his dark lord
His helping hand grows lonely and bored,
Now the sparkling Castle is oppressively still,
With no more Drac chat Iggy has time to kill.
Igor misses the old master's companionship
So he drops into the village tavern for a nip,
In the darkest corner Igor will gloomily sit,
The villagers tend to shy away from him a bit.
Igor casts a sad, tragic and lonely figure,
He has just one friend, butt uglier and bigger,
He has a battered mug, he's a bleedin' nightmare,
When it comes to ghastly looks he's had his share.
He causes quite the stir down at the Shtup Inn,
Striding through the door and shambling in,
Before he begins one of his monstrous binges
He's already blown the door off its hinges.
This poor creation has been badly built,
With more stitches than a patchwork quilt,
Any good Doc would stop, then start again,
Well… any decent Doctor with half a brain.
But just as long as the tab gets paid
They get a warm welcome from the barmaid,
For it's with a prodigious thirst both are blessed;
It's gonna get wetter and wilder than Oktoberfest.
Big Bertha became one busy busty fraulein
Taking the pilsner out to that ugly Stein,
But sadly the more good spirits they uplifted
The more downbeat the mood shifted.
The conversation Igor totally dominated,
His offsider couldn't be less animated,
Frankly, all he could do was silently nod,
He's lost his tongue, the poor sod.
It would take twenty thousand volts
To get a grunt out of that bag of bolts,
He's strong, he's silent, he's big and dumb,
But give him 1.21 gigawatts and hear him hum!
Soon the gruesome twosome were knockin' it back
Tossing out toasts in memory of dear old Drac,
For despite the dark life the Count had had to live
He always tried to turn A Negative into B Positive.
First comes far too many 'Cheers'
Then come the maudlin tears,
Over this not-so-pretty pair
Settled a funereal air.
Now it's Igor who silently sits
While his beer buddy falls to bits,
Is there any sight sadder than
A big blubbering Bitter man?
In the olden days those tears would invoke
Laughter and jeers from the towns volk,
And with pitchforks they'd be pointedly driven away,
Now this odd miss-matched couple are here to stay.
Thanks to the terms of Dracula's will
Igor gets to keep his Castle on the hill,
The peasants long to burn it to the ground
But Igor owns all the farms for miles around.
So there won't be any torches lit,
No rowdy unruly mob pitching a fit,
Any fiery outbursts, Frank will stomp 'em out,
Peasants, his presence means- no arson about.
Now in a room once cold dreary and eerie
Igor sits by a blazing fire, bright and cheery,
His serfs remember Dracula as vile and hateful;
When Igor stirs the ashes he remains truly grateful.


text:
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Broadcasters share memories of Connecticut radio
NEWINGTON, Conn. (AP) -- Modern-day satellite radio and televisions that pause and fast forward through commercials; these contrivances aside -- the discussion at Paradise Pizza on East Street on a recent night was about a much slower, simpler time in broadcasting.
The Newington Kiwanis assembled a variety of newscasters, TV and radio personalities both young and old, for a nostalgic stroll into the old days for the club's monthly public forum.
The evening's most esteemed guests were "A Bunch of Old Broadcasters" -- folks who spent many years in the business and who meet at Hartford's legendary Arch Street Tavern monthly to revel in the old days.
The group spent the evening sharing memories of local airway icons like Mitch Betters, Bob Steele, Bob Ellsworth, Ben Hawthorne, Una King, Ivor Hugh, Dick Bertel, Arnold Dean, Charlie Parker and others.
Brad Davis, who this year celebrated his 35th anniversary as the morning man on WDRC-AM, was a guest speaker. Davis recalled the day he was hired by WTIC as a young man, igniting a flurry of laughter across the room.
"I walked into the set and said, 'I don't know anything about the teleprompter or microphones,'" said Davis, rehashing his reaction to a commercial for 'Friend's Beans' during which he told the man who would soon be his boss that his grandmother used the brand to make her signature hot dogs once a week, a quirky move that ended up earning him his position with WTIC.
Davis' commentary led into that of former Channel 30 News anchor and WTIC-AM (1080) broadcaster Bill Hennessy, who was 22 when he was first hired by the station.
Hennessy, who co-emceed the event with Steve Parker (the son of the late-great Charlie Parker of WDRC) offered the media professionals in the room some wise advice about an industry he had far-reaching history in:
"If you are honest and tell the truth and are loyal to your sponsors and your audience, you'll succeed."
Hennessy went on in his career to win an Emmy for his investigative prowess in a refugee story, citing "passion, inspiration and hope" as three qualities any radio personality should possess when addressing their listeners.
Although Arnold Dean came sauntering in a few minutes late, it didn't forestall the enthusiastic applause that broke out as soon as the large group saw the familiar figure in television and radio for almost 65 years arrive. Dean founded WTIC SportsTalk in 1976 and went on to talk with favorites like Jackie Robinson, Joe DiMaggio and Ted Williams.
When Dean was handed the microphone at Monday night's program, he shared his memories of interviewing all the big band greats, like Benny Goodman and Duke Ellington, and chronicled moments from an unforgettable Red Sox game in 1977.
But one of the Rocky Hill resident's more notable interviews was with former White House Press Secretary Pierre Salinger, shortly after the assassination of President John F. Kennedy in 1963.
Many of the guests who attended the evening knew each other, but hadn't been in touch in years. Program Chair Al Cohen, a long-time Kiwanis member, was happy to see old friend Ivor Hugh, who was music director at WCCC (AM) for over 10 years starting in the early '50s and also known for his 'Good Evenin' Good Music' program on WJMJ.
"One of my greatest joys is having listeners make requests," said Hugh, who just celebrated his 85th birthday.
"In all my years of broadcasting, the thing I loved most about radio is it's so personal," he added. "You're in the car and the person you're listening to becomes your friend. I don't think any new technology can take that away."
Phil Callan, a former broadcaster with WMMW-AM, WRCQ-AM and WDRC-FM, was another guest speaker.
"I had a lot of fun in radio. I like to tell people I never made a lot of money but I never got up in the morning dreading going to work," he remarked.
Information from: New Britain Herald, http://www.newbritainherald.com


text:
Just like its titular storybook character, THE BABADOOK came out of nowhere and enchanted and haunted audiences. After picking up a lot of steam at its Sundance premiere, the story of a widowed mother and her son coming up against a creature right out of legend found itself a large audience after it arrived on Netflix. Being a critical and financial success it was only a matter of time before we saw the film's writer and director Jennifer Kent's next project taking shape.
Thanks to The Hollywood Reporter, we know that Kent's follow-up film, titled NIGHTINGALE, is starting to find both financing and its cast. Per THR, NIGHTINGALE "is set in Tasmania in 1825, and follows a 21-year-old Irish convict who, after witnessing the brutal murder of her husband and baby by her soldier master, takes justice into her own hands, finding an Aboriginal male tracker to enter the wilderness with her to seek revenge."
Sam Claflin, previously seen in THE HUNGER GAMES, THE HUNTSMAN: WINTER'S WAR, and ME BEFORE YOU, will star in the film along with Aisling Franciosi, Damon Herriman, Ewen Leslie and Harry Greenwood. Also rounding out the cast is Aboriginal Djuki Mala dancer Baykali Ganambarr and East Arnhem Land indigenous model Magnolia Maymuru.
Along with the cast, the film is finding financing from Bron Creative, Made Up Stories, Screen Australia, Screen Tasmania, and the South Australian Film Corporation.
What did you think of THE BABADOOK? Does it get you excited to see Jennifer Kent's next film?


text:
MATEC Web Conf.
Volume 125, 201721st International Conference on Circuits, Systems, Communications and Computers (CSCC 2017)
|Article Number
|Number of page(s)
|Published online
|04 October 2017
Triangulation positioning system network
1 University of Brunel - Dept of Electronic and Computer Engineering, UB8 3PX Kingston Lane, Uxbridge Middlesex, United Kingdom
2 Technological Educational Institute of Crete (TEI of Crete) - Dept of Electronic Engineering, Romanou 3 Chalepa Greece
This paper presents ongoing work on localization and positioning through triangulation procedure for a Fixed Sensors Network - FSN.The FSN has to work as a system.As the triangulation problem becomes high complicated in a case with large numbers of sensors and transmitters, an adequate grid topology is needed in order to tackle the detection complexity.For that reason a Network grid topology is presented and areas that are problematic and need further analysis are analyzed.The Network System in order to deal with problems of saturation and False Triangulations - FTRNs will have to find adequate methods in every sub-area of the Area Of Interest - AOI.Also, concepts like Sensor blindness and overall Network blindness, are presented. All these concepts affect the Network detection rate and its performance and ought to be considered in a way that the network overall performance won't be degraded.Network performance should be monitored contentiously, with right algorithms and methods.It is also shown that as the number of TRNs and FTRNs is increased Detection Complexity - DC is increased.It is hoped that with further research all the characteristics of a triangulation system network for positioning will be gained and the system will be able to perform autonomously with a high detection rate.
Key words: Fixed Stations Network / Triangulation / Localization / Network Blindness / Triangulation Area
© The Authors, published by EDP Sciences, 2017
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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