text:
Renee Doyle, DMD, MS
Renee Doyle, DMD, MSLocations:Specializing in:
Get To Know
Dr. Renee (Reilly) Doyle is an orthodontic specialist and dentofacial orthopedics. Dr. Doyle was born and raised in Columbia, IL and is a graduate of Columbia High School. For her undergraduate studies, she attended the University of Illinois Urbana-Champaign where she earned a Bachelor of Science in Chemistry. She went on to earn her Doctorate of Dental Medicine at Southern Illinois University School of Dental Medicine in Alton, IL. Following dental school, she continued her education at Saint Louis University Center for Advanced Dental Education. She completed a 30-month residency of specialized training in orthodontics and received a specialty Certificate in Orthodontics, as well as a Master of Science in Dentistry and Orthodontics.
Dr. Doyle is certified to provide braces and Invisalign® to children, teens, and adults.
Dr. Doyle is an active member of the American Dental Association, the American Association of Orthodontics, the St. Clair District Dental Society, the Orthodontic Education and Research Foundation, and the Washington University Orthodontic Study Club. Locally, she is a member of Immaculate Conception Church, Columbia Kiwanis Club (Terrific Kids Advisor), and the Columbia Volunteer Fire Department family.
Dr. Doyle resides in Columbia, IL with her husband Steve, their two sons Bryce and Hudson, and golden retriever Cally. Outside of the office, Dr. Doyle enjoys running, golfing, and spending time with family and friends. In the future, Dr. Doyle and her family look forward to becoming even more involved in their hometown community.
Get To Know
They found their smiles at Rediger.
Actual patients from Rediger Orthodontics.


text:
As someone with a heart filled with wanderlust, not having a travel buddy never much bothered me. Or keep me from getting my passport stamped. In fact, travelling solo is one of my favourite ways to travel. The freedom and being alone with my thoughts is what gets me going and fuels me. But let's not glorify it endlessly, because solo travelling – just as much as travelling with someone – can have its downsides. I've asked eight fellow travel bloggers with tons of solo travelling experience to share their personal downsides of solo travel too:
Having to Pay for a Double Room
submitted by Juliana – The Discoveries of
I love travelling solo. There's something so refreshing about being able to do whatever you want, however you want on a trip. That said, there are always downsides – one of them being that you pretty much always have to pay for a double room unless you fancy booking into a dorm. That, my friends, is a guaranteed way to eat into your budget.
It's fine when you're travelling with someone – you can just split the cost of the room. But paying for rooms when you're flying solo can add up to a hefty amount, even when you're not staying in fancy places.
I remember the first time that I travelled alone, I was absolutely horrified by how much I ended up spending on accommodation. These days, I try to negotiate the cost of the room down – sometimes, like for my fortnight in Bali, it totally works. Others, not so much. But it's always worth a try.
↠ Read Juliana's solo travel tips for London.
Reassuring People at Home You're still OK
Submitted by Maire – Temples and Treehouses
Before my first solo trip, I worried that I wouldn't have as much fun on my own, or that I would struggle to find my way around a foreign country by myself. Instead, I discovered that it's a great feeling dealing with challenges on your own, and you honestly can have so much fun by yourself.
But a surprising outcome of solo travel was needing to regularly reassure friends and family that I was ok! During my 6-month solo trip, I received a lot of messages from home, all asking if I was still travelling on my own. I didn't want people to worry, and I was really grateful for their concern. It made me realise how much more important staying in touch is when you're so far away.
↠ Read about Maire's solo travel experiences.
Different Mindsets
Submitted by Chris Backe – Becoming a Digital Nomad
I enjoyed the solo travelling life as an expat living in South Korea. After a workweek full of kids and policies and the occasional parent, it was nice to just get away and be a traveller.
The biggest downside of solo travel? There was no one to share the adventure with.
And then I met a girl and we went from 'date #1' to 'weekend-long dates' in a couple of months. Will she enjoy the same places as I do? Does she have the same energy level to tackle a place? Do we want to check out the same places when we go to a new city?
A mismatch here is a potential downside — or simply the realization that not every person need to be in lockstep with their partner. While dating, we both knew that we wanted travelling to make up a big part of our lives. Even in a serious relationship, it's sometimes better to go solo to enjoy a place your way.
Too much Unwanted Attention
Submitted by Lisa – TheHotFlashPacker
I am not young, skinny, or cute, but I still get unwanted attention and even propositions, by men when I travel solo. While I kind of expect men to talk to me in a bar, the most persistent men are often on the street or in public transportation. Despite different approaches from acting indifferent to explicitly telling them to go away, sometimes they persist. Sometimes a guy will start walking along while I'm walking down the street and will try to chat me up. Often it will include an invitation to do something with him.
One of the funniest times a guy just wouldn't go away was in a shuttle bus from Armenia to Georgia. The guy in the seat in front of me started chatting me up. He kept on talking, loud enough for the whole shuttle to hear. Eventually, he asked, "are you married?" and I heard several people in the back of the shuttle bus yell "YES!"
↠ Read Lisa's tips for solo camping.
Not Being Trusted as a Solo Male Traveller
Submitted by Dana – Discover Discomfort
Travelling in the Middle East is challenging as a solo female, from what Jo tells me. In comparison, I wouldn't say it's "challenging" to travel as a solo male, but there are prejudices against me to constantly battle. As a man, I am assumed to be more of a threat or a potential creep. People are less likely to spontaneously help me than a woman, and definitely unlikely to agree to meet up soon after meeting.
Now that I'm travelling with my partner Jo in Egypt to learn Egyptian Arabic, I notice many unanticipated benefits. People are warmer and more likely to strike up a conversation with us (well, with her… but I'm there). Friendly strangers often exchange numbers and propose catching up for coffee or lunch soon after meeting us! And we have more options of places to stay in the Middle East, where conservative traditions (and safety guidelines) prohibit single men from staying in many household situations (for example with a single female roommate).
↠ Read Dana's recommendations on travelling solo in Egypt.
Missing Good Chats with Friends
Submitted by Paul – Journey Compass
On the upside, as a solo traveller, you do tend to meet a lot more new people as compared to when travelling as a couple or in a group.
The main downside of solo travel to me is not having good friends around that you can have a chat with. Of course, you do meet people on the road, but often you're on your own too.
It differs per location to me though, for example when I am in Boracay, it's easy to meet new people and have social interactions here and there, since the location is very central, and it has a vibrant social vibe. On the other side of the coin, when I stay in Kyoto, I feel less connected to the rest of the city. So to me, some travel destinations are also just better suited for solo travel than others.
↠ Read about Paul's travels here.
Dining Alone
Submitted by Claire – This Travel Lover
I love travelling alone. However, one of the downsides of solo travel is how hard it is to go out for dinner alone. I used to hate solo dining, but over the years I've become quite accustomed to it. Even if most waiters haven't! That look of surprise and pity when you say 'table for one', then they lead to you the tiny table in the back before ceremoniously clearing the cutlery away from the empty seat in front of you. It doesn't upset me anymore, but I am consistently irritated by how waiters behave – we all have to eat, so I really don't see why someone eating alone is such a big deal!
Actually, that's not the worst thing about dining alone, not being able to order my favourite dishes is simply torture – why don't they make paella dishes for one? Or tapas? Having to forgo some of the tastiest dishes just because I'm alone really isn't fair.
↠ Read Claire's tips for female solo travellers.
The Struggle to Get Great Photos
Submitted by Anna – My Travel Scrapbook
Solo travel is amazing but there are times when you wish you had a partner with you. One of those times is when you want an incredible photo with you in it. There are many tips like bringing your own tripod and setting up the auto timer. These photos require a lot more time though, especially knowing your partner would do this within 10 seconds.
The downside of solo travel? Often your only choice is the other travellers and asking them to take a photo of you. You internally debate whether they will know how to use a DSLR or whether to just hand them your phone and put up with a lower quality photo. Once you have managed to convince someone to take a pic and they then ask the obligatory – yet rhetorical – question of whether the photo is good. You feel awkward asking for another photo and wish you had a better camera buddy!
↠ Read about Anna's travel adventures here.
Medical Emergencies
While I can relate to many things the others have just mentioned, for me, the most frightening and worst of all downside of solo travel is having to go to the ER in a foreign country.
I've had emergency surgery in Mexico a couple of years ago. And had to go to the ER in South Africa just a couple of months ago. Plus I've had my fair share of emergency dentist visits abroad too.
All of this happened while I was travelling alone thus had to take care of everything myself. From calling my travel insurance to getting myself to the hospital or doctor etc. It made me realize how far I can push myself until I reach a safe place. Luckily I've always been conscious to deal with it all. I am frightened of getting in an accident and having to trust others to make the right decisions for me.
View this post on Instagram
When life throws rocks at you and travelling becomes a real challenge. Over the past days there was little that didn't go well. On my first day in Port Elizabeth we went scuba diving und during the back roll entry from the boat, I fell on my ear or some air was trapped under my hoodie and it hurt shortly. Since descending and ascending didn't hurt, I kept on diving for three short dives that day. At night my ear hurt – not bad, but I wasn't comfortable. So I called a dive doctor and he assured me that it wasn't anything serious and that I would stay out of the water for a few days. Side note: the whole reason I even came to South Africa was because of a two week scuba and snorkel trip out of PE and that day was the first day of this tour. The next day my ear was better but I got a tooth ache. Since it was weekend and no emergency dentist to be found, I headed to a clinic for meds. The day after I went to see a dentist who had to do a root canal. But the tooth was so inflamed that it continued to hurt badly the following days. Then out of nowhere my ear started to hurt again. But unlike before I was in a lot of pain. I thought the antibiotics would just need another day to kick in but I couldn't even think straight and woke up in the middle of the night crying because of the pain and headed to the ER. The doctor prescribed an IV-cocktail of antibiotics and pain killers to make me feel better. I headed back to my accommodation with a long list of meds to take. Although I felt slightly better, I was really weak and couldn't even stand up or eat. I slept for more than 20 hours that day and just remember it all very blurry. Two days ago I finally felt better and went out for lunch. It was delicious, but then it made a cracking sound in my mouth. A different tooth had split into two parts (and of course it was late Friday). I just sat there in my chair and burst into tears. Why? I though. Luckily the dentist I had seen before was able to see me and fix it right away. Instead of scuba diving and snorkelling with dolphins, whales and sharks the past week I saw clinics and an ER. 😭 #travelling #southafrica #austrianblogger #morerealityoninstagram
What do you think are the downsides of solo travel? Are there any at all? Share your thoughts in the comments below!
ps. pin me!

subset: commoncrawl


text:
Before we process your gift, would you consider something?
Will you help rescue 3 babies from abortion in the next year by converting your one-time gift into an ongoing $15 monthly gift?
We know exactly how much it costs to save a baby from abortion. It's true. A gift of $60 can help save one baby from abortion. That means you could help save 3 babies in the next year with a smaller monthly gift of $15 today. Your monthly gift will equip pregnancy resource centers across the country with ultrasound machines and resources through our Option UltrasoundTM program. This allows mothers considering abortion to see their babies, hear their heartbeats, and choose life.
You will become part of an exclusive group of people committed to sharing the Gospel of Jesus Christ and communicating Christ's love and affection to thousands of mothers through the heartbeats of His little ones.
Will you convert your gift to a monthly gift and help save babies from abortion on an ongoing basis?


text:
It started innocently enough about a decade ago.
"I'll do it once or twice," I thought. "It's no big deal."
At first, it wasn't.
Then a few times a year, turned into a few more times per year, and as the years piled on, so did the obsession. Now I'm here at the beginning of yet another year, and my once or twice habit, has turned into a financial drain that has added a lot of undue stress to my life.
Nearly every dollar I make, I struggle over the decision of using it to pay a bill, put away for a rainy day, or feed the beast. The beast is winning more and more often.
I was on the prowl all night last night looking for a fix, and finally went to bed depressed because I didn't have the cash to score what I wanted, what I needed.
I feel like I'm losing control, which means my friends and family probably realized I lost control a long time ago. The addict is always the last to know.
My stereo equipment is inadequate, and my vinyl collection isn't what i want it to be. It's sad but true. It's consumed me.
Last night I was searching for tube amplifiers, and phono preamps with tubes, and speakers capable of making such a purchase worthwhile. No matter where I turned, or what dark Internet rabbit hole I went down, I never had enough cash to be satisfied.
It didn't used to be this way.
I bought a few records on a whim one day. I didn't even have my own turntable. I had to use one belonging to someone else. It wasn't long before I was on the hunt for my own.
That was when the cheap stuff was just fine. If it plugged into my receiver, and made noise, it did its job.
Then the records began to pile up. Not too many at first. Just a few here and there. It didn't become a weekly habit for several years, and it wasn't until earlier this year that I became a daily searcher.
Three years ago, I decided my turntable wasn't good enough.
Then I got my hands on a classic Realistic LAB-395 Direct Drive turntable with its original Shure RXT-4 MM Cartridge, that only needed a stylus replacement.
Then my receiver wasn't good enough.
It still isn't, but until I do something with my speakers, there's no point in chasing that dragon.
Since the speakers and tubes are still out of reach, I keep eyeballing an upgrade on the turntable, and maybe even a better phono amp that doesn't have tubes.
The cycle is endless now.
If I'm not looking for high-priced audio equipment, I'm looking for over-priced accessories like dust arms, record cleaners, and stabilizer clamps.
I'm even considering learning how to solder and assemble electronics so I can get shit to put together myself.
I'm sick. I need help.
If it wasn't for the steady flow of records I bring into the house, I'd be a miserable wreck with a bad case of the shakes.
There aren't any Betty Ford clinics for this. I've just got to deal with it on my own.
I just hope I can come to grips with my problem, before I start pawning my grandmother's jewelry and prostituting myself for .50 cents per ride downtown.


text:
Ugh… I have an ulcer on my cornea. It is kind of crazy that I saw 3 different doctors today. I spent much of the afternoon and evenings visiting my GP office at 2pm, LGH Emergency at 4:30pm, then at the VGH Eyecare Clinic at 8pm. The above picture is from August 2009 when I had a corneal abrasion – thought possibly due to sand/grit from hanging out at Kalmalka Beach in Vernon, during a wind storm. Obesity can lead to corna ulcer apart from different unhealthy conditions, exercise and weight loss are some of the best ways to prevent this, bioharmony advanced can help you keep a healthy diet.
My regular doctor was all booked up so I saw her office partner Dr. Yam. After putting some dye on my eye, she thought I might have a "tear" on my cornea, so she sent me to emergency. At Lion's Gate Hospital, I saw Dr. Andolfatto, who confirmed there was something wrong on my eye, and made an 8pm appointment for me to go to the Eye Clinic at VGH, where I saw Dr. Silver who made the final diagnosis. Nice to know we have a great healthcare system that can set me up with an ophthalmologist at 8pm on a Friday night.
Well.. if it was a stomach ulcer… I wouldn't be able to drink any alcohol. But since I have an eye patch, and the ulcer is on my eye… I can have a shot of Captain Morgan for every drop of anti-biotics that I put in my eye… which is each hour.
What Are Medical Treatments for a Corneal Ulcer?
- Your ophthalmologist will remove your contact lenses if you are wearing them.
- Your ophthalmologist will generally not place a patch over your eye if he or she suspects that you have a bacterial infection. Patching creates a warm dark environment that allows bacterial growth.
What Medications Treat a Corneal Ulcer?
- Because infection is a common occurrence in corneal ulcers, your ophthalmologist will prescribe antibiotic eyedrops. If the infection appears very large, you may need to use these antibiotic drops as often as one drop an hour, even throughout the night. Some patients require more than one type of treatment and some require eyedrops that are compounded at specialty pharmacies or in hospitals. Find the latest supplements and medicine reviews at sparkhealthmd.
Are There Home Remedies for a Corneal Ulcer?
- If you wear contact lenses, remove them immediately.
- Apply cool compresses to the affected eye.
- Limit worsening of infection by washing your hands often and drying them with a clean towel.
LESSON LEARNED: update contact lens solutions, don't leave lens in eyes for too long… otherwise corneal abrasion or ulcer will develop. "Deep ulcers extend into or through the stroma and can result in severe scarring and corneal perforation… This type of ulcer is especially dangerous and can rapidly result in corneal perforation, if not treated in time." http://en.wikipedia.org/wiki/Corneal_ulcer


text:
The Project Health
The Camacho Dental Association tries to help any community that lacks dental assistance, people from any place or background that for different reasons find it very difficult to get access to modern medicine.
The C.D.A. also feels proud to have provided some help to the Evangelic Community of the Temple of Mahanain.
This community does not live in isolation from modern life, but face many difficulties due to poverty and inequalities among ethnic groups in their country, Panama. Due to their social and economic situation they lack dental treatment, and most of the population has poor dental hygiene.
This religious and humble community is also in desperate need of health assistance. The C.D.A. has given away hundreds of T-shirts from the association to spread awareness on the importance of Dental Health; as well as providing them with tooth brushes, education on dental hygiene techniques, and diagnosis of cavities informing of the necessity of visiting a Dental professional.
The ultimate goal for the Camacho Dental Association is to bring portable materials to these communities in order to also be able to treat their dental problems.


text:
Touch 'n Go-Ant Financial deal paves the way
ELECTRONIC wallets (e-wallets) are all the rage in countries like India and China but only make up a small presence in Malaysia.
And yet, a race has begun for e-wallet operators to gain a strong foothold in the market.
This week a significant deal was inked – Touch 'n Go (TNG) teamed up with global player Ant Financial that operates the Alipay e-wallet in China mostly. That TNG has 10 million cards issued in Malaysia and is majority owned by one of the largest banking groups in Malaysia, namely CIMB Group Holdings Bhd is a big deal, says an industry player.
"You could say the deal adds impetus to the rest of us to get cracking to fight for this market."
E-wallets are essentially apps residing on your mobile device that can be loaded with money and used to pay for goods and services as long as merchants accept that payment method.
The usage of such mobile payment systems are welcomed as part of the global move towards cashless societies, a direction most central banks are increasingly pushing for as it costs a lot to keep cash in circulation. The digitisation of money is also safer and cheaper to manage and promotes financial inclusion and weeds out corruption.
In Malaysia, the ratio of currency-in-circulation versus GDP stands higher than that of advanced economies.
To be sure, the move towards the use of debit cards was and continues to be a key move towards using less cash.
E-wallets are also ideally suitable for small or micro transactions.
An oft-cited anecdote of these digital payments are that they are used even by chai-wallahs in India. And in China, some beggars have started using QR codes to collect their alms.
But while e-wallets issued by giants such as Alipay and Wechatpay in China and Paytm in India have a large user base with billions of dollars being transacted via those systems, it is not going to take off like wildfire in markets like Malaysia.
And here's the reason why: the market is already well served by banks and most Malaysians have at least a debit card to use. Cash is also widely available and accepted.
"The main competition to e-wallets here is simply debit cards, at least for now," says a banker.
In other words, it is going to take a lot of convincing for users to begin downloading and using e-wallets. So why bother?
The banks, not wanting to miss out on the e-wallet wave, are clear that it is something they have to do.
"It (the e-wallet) is a growing trend because of its ease of use. Banks issuing e-wallets are readying to respond to customer's needs," says a banker.
The team comprising CIMB and TNG officials had worked with Ant Financial for almost a year to seal this deal. CIMB owns 52% of TNG while MTD Capital Bhd and PLUS Expressways Bhd own 28% and 20% respectively. The deal also marks the seriousness of CIMB Bank's move into the fintech space.
In April, CIMB Group chief executive officer Tengku Datuk Seri Zafrul Aziz said the bank was prepared to "invest significantly in fintech propositions that will add value and enhance the customer experience" of their 12 million customers across the region.
At the signing event this week, CIMB Bank CEO, group asset management, Effendy Shahul Hamid said TNG's tie-up with Alibaba's Ant Financial Services Group to build an e-wallet for the Malaysian market is an exclusive deal.
"While the digital platform that we will build will be open to integration with all other financial institutions here, the partnership with Ant Financial to build a specific e-wallet component for Malaysia is exclusive to TNG," Effendy said.
He stressed that the partnership was synergistic in many ways. "We feel that the joint venture will have a competitive advantage, leveraging on TNG's strong domestic presence and adding a proven technology platform in the form of Alipay."
Ant Financial has inked similar deals with a number of institutions in a few countries in the region, such as Emtek Group in Indonesia, CP Group's Ascend Money in Thailand, Paytm in India, Kakao Pay Corp in South Korea and Mynt in the Philippines.
The need to woo customers
All e-wallet issuers will have to invest to win over customers. For the TNG/Alipay venture, for example, merely having 10 million TNG cards in issuance does not automatically translate into the venture securing users for its e-wallets. What TNG would need to do is convince customers to download the e-wallet into their mobile devices and start using it. That is essentially the challenge for all e-wallet issuers.
Industry experts say it will take a lot of encouragement in the form of incentives and other sweeteners to attract users to e-wallets.
"There is going to be significant customer acquisition costs to woo people using cash and debit cards to the e-wallet. But will that be a sustainable venture?" questions Naysan Munusamy, a fintech entrepreneur. He says aside from that, there are also significant merchant acquisition costs to be considered.
But the returns could be potentially lucrative. E-wallet issuers get to enjoy a mouth-watering prospect – the float of money in the accounts. This is now a well document story of how Alipay had access to hoards of cash that sat in the e-wallets of its millions of users, an unintended bonus that enabled them to make lots of money from the interest accrued.
The huge amount of float, some argue, could be lead to the e-wallet operator to have a bank-like balance sheet.
But one banker argues that the days of this "free float" are coming to an end.
"The next evolution in this game will be synching the e-wallets to the bank accounts of users. This means that there will not be a reason to 'top up' your e-wallet anymore, rather it would be a direct deduction from the users' savings account sitting in a bank. This, he argues, means there will hardly be a float left for e-wallet operators. So, why chase the e-wallet game then? The answer lies in eco system ownership and big data, a term used to describe the large amount of data pooled from users, which in turn can be monetised through targeted marketing efforts.
Who will win?
Considering it is early days, it is hard to tell who will concur the e-wallet space. Five Malaysian banks and as many as 23 non-bank entities hold e-money licences issued by Bank Negara which are allowed to issue e-wallets. Not many of them are active in the e-wallet space, and are focused instead on loyalty and petrol cards.
The big boys are in the game. Malayan Banking Bhd, the largest bank in the country, lays claim to being the first to launch the country's first mobile wallet payment platform in the form of MaybankPay. Subsequently, it partnered Samsung to launch the Samsung Pay mobile wallet.
Maybank says the transactions and usage of its mobile wallets are growing by more than 50% annually, a much higher pace than its growth of credit and debit cards although the latter still accounts for the bulk of non-cash transactions.
Then there are the China giants. Even before Alipay announced its tie-up with TNG, Tencent Holdings Ltd said it had applied for a licence in Malaysia to offer local payment services via its WeChatPay, in what would be a first for the platform outside of China.
The advantage WeChat has is that many Malaysians already use this messaging app, meaning that they merely need to be convinced to switch on their payment function and use it in outlets in Malaysia.
Niche players are also getting into the scene. For example, a brand called Kiple is being trialled in the food and beverage (F&B) and services space, with close to 1,000 outlets in the Klang Valley accepting payment via this e-wallet.
Kay Tan, the CEO of Green Packet Bhd, the licensed issuer of the Kiple e-wallet says it is not just about making ease of payment but building a collaborative ecosystem to benefit both consumers and merchants. We are building a platform for continued patronage, ease of use, tracking and relevant rewards among others."
He adds that the winners will be those who offer a better service and value add both to the consumer and merchants.
Did you find this article insightful?


text:
This content has been marked as final. Show 8 replies
Re: How hard is to get a loan?LUCKIEST Aug 3, 2009 6:19 PM (in response to mgdphotos)How hard is to get a loan, Welcome
If you want to raise money to finance a new business, you need a business plan.
Tell us more. Go to Members page and share some info.
Do you know about SCORE?? SCORE is FREE
<!--Session data-->
Re: How hard is to get a loan?mgdphotos Aug 6, 2009 10:17 AM (in response to LUCKIEST)
Thanks for replying
I do have a business plan, but is only 3 pages I have notice that a lot of business plan is more than 3 pages so I'm not sure if mine is good enough to present it. I've heard from Score but I tried to contact a local counselor, I have send several emails and I have not received a reply back. My husband knows a guy the owns more than 8 restaurants in my area, we are meeting with him today to see if he can help us with the money part. Do you think it will be a good idea? Give me some advice, please
Re: How hard is to get a loan?colin104 Aug 3, 2009 6:19 PM (in response to mgdphotos)For a business loan the most important thing is your business plan. Make sure you have a good business plan which "proves" that you have the skills, knowledge and vision to lead your business to success. The only thing you need is part of the money, but the lender's risk is minimal because of the aforementioned and because you will co-finance the venture yourself. Lenders ask for your credit history, business plans, collateral, etc only to minimize risk. Try to convince them that your restaurant business bears negligible risk.
Re: How hard is to get a loan?colin104 Aug 3, 2009 5:15 PM (in response to mgdphotos)You have to make sure you have a good business plan. Lenders try to minimize risk, so if don't have collateral or a perfect credit history, you should have at least a very good business plan that "proves" that you have all the skills, experience and vision necessary to bring your venture to success.
link=http://www.digitalhotspot.comDigitalHotSpot[/link] - the place for online business owners
Re: How hard is to get a loan?mgdphotos Aug 6, 2009 10:17 AM (in response to mgdphotos)I do have a business plan, but compare to other business plan that I have seen mine is not good I guess because is small compare to other plans.
Re: How hard is to get a loan?colin104 Aug 8, 2009 6:03 AM (in response to mgdphotos)If you can afford it get professional help to prepare a good business plan. If you can't, then I suggest you start with a good template and put your best effort to prepare it yourself. You can find excellent business plan templates at www.next-to-free.com
Re: How hard is to get a loan?Anderson1978 Aug 8, 2009 9:33 AM (in response to mgdphotos)If your credit is not good, don't waste your money paying someone to write a business plan, because you will not be approved for a bank loan. If your credit is weak, the bank won't overlook that just because you have a business plan. For the amount of money you are looking for, you are more likely to finance your business if you borrow from friends and family. If you can't raise enough that way, you can always use credit cards.
My solution is not ideal, and does not fit the boilerplate advice that you'll get from small business advisors. But most entreprenuers will tell you that at the beginning, you scratch and claw and do what you need to do.
Re: How hard is to get a loan?bentenn Aug 8, 2009 6:17 PM (in response to mgdphotos)If you have been successful making and selling cakes and other desserts, my suggestion is to do more of it and earn your way to finance your dream business. And from experience, $25k is really not much money to start a restaurant of almost any size. And yes, a 3-page business plan suggests you may not have reviewed all the issues you will face with a much more complicated business than your current business including a detailed one year projection, etc.
One idea I suggest to clients is to continue doing what you are doing now to continue to earn some money and build on your past success while taking a job, any job, at a restaurant to learn more about the ins and outs of that complicated business. Learn from the inside what issues you will be facing from ordering food to managing a crew of employees at various skill levels to marketing to location and much more. A 1-year stint in someone else's restaurant can be a great education before getting started on your own. And please know the #1 new start up business that fails most often is opening a restaurant.
All the best to you. And if you do need professional no cost help with your business plan and suggessions on how you might secure some additional funding, contact your local Small Business Development Center (SBA) for counseling and advice and low cost workshops. Ben
Go to original post
Reply to original post
I've been doing cakes, pastries and catering for the past couple of years. But I want to open a restaurtant I do have some money save up but I know that it will cost me over 25,000 to open a restaurant. How can I get a loan if my credit is not that good? Am I going to have a lot of problems getting a bussines loan?
I've been doing cakes, pastries and catering for the past couple of years. But I want to open a restaurtant I do have some money save up but I know that it will cost me over 25,000 to open a restaurant. How can I get a loan if my credit is not that good? Am I going to have a lot of problems getting a bussines loan?


text:
Cool feature
Short, concise description of the idea
A button called "on this day". you press it and see previous posts over the years on that day.
Full description of the idea
I think the sentence above explains it pretty well. Might be nice to have a "friends on this day" too where you could see what everyone on your friends list was doing on that day.
- this is a little crazy! I have to put a benefit? um it will be nice for your users!!?
- THis is even sillier, I have to list problems? Isnt this your job. Im just the idea guy.


text:
Unity is becoming even more critical to indie (and AAA) developers around the world. Hit games like Hearthstone, Wasteland 2, Cities Skylines, and many others were developed on the platform.
Here's a video from the Unity Keynote at GDC 2019 on some of the exciting changes coming to the platform in the year ahead:
Whether you are an event coordinator, press, or general attendee, if you have an event video to share with us, please let us know and we'll be happy to feature it.


text:
The HMinfo Research Library contains an in-depth collection of materials on home modifications and related subjects.
The Research Library does not lend books and other items. Under special circumstances, requests to use the library may be made by emailing .
Millions of Americans are plagued by serious problems of inadequate health care benefits, limiting their access to services & creating hardship. For those under age 65, the problem is a lack of insurance, while for those 65+, the problem is one of underinsurance in terms of both cost & coverage, particularly for long-term care. Policies of cost containment & shifting costs to consumers have exacerbated these problems, & current health policy proposals offer little respite. Arguments are made for a public national health care program, & policy interventions are considered at four levels: incrementalism, modification, alteration, & transformation. A proposal is presented for universal health benefits that are organized & operated to eliminate for-profit medical care & to promote social & preventive care.
Reads 273


text:
Diving In Shallow Water
Category: /General/I am rolling down,
(19 views)0
down, in dream, thinking of
you pulling a thorn.
A butterfly flirts.
You find shelter in pain. The
power wants to celebrate the dark.
The hands tell your
anxiety. They tremble while
holding a pen writing a name.
Favorite Favorite Comment Comment Share Share
Report an item by sharing it with support.
© individual authors and creators. Create, Share and Profit at etastic.com.


text: Implementation and Operational Research: Epidemiology and PreventionTreatment Interruption in a Primary Care Antiretroviral Therapy Program in South Africa: Cohort Analysis of Trends and Risk FactorsKranzer, Katharina MBBS, MRCP, MSc, MSc*†; Lewis, James J BA, MSc, PhD‡§; Ford, Nathan MPH, PhD‖; Zeinecker, Jennifer MBChB, MPH*; Orrell, Catherine MBChB, MMed, MSc*; Lawn, Stephen D BMedSci, MBBS, MRCP, MD*†; Bekker, Linda-Gail MBChB, FCP, PhD*; Wood, Robin BSc, BM, MMed, FCP*Author Information From the *The Desmond TUTU HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Science, University of Cape Town, South Africa; †Department of Infectious and Tropical Diseases, Clinical Research Unit, London School of Hygiene and Tropical Medicine, London, United Kingdom; ‡Aurum Institute for Health Research, Johannesburg, South Africa; §Department of Epidemiology and Population Health, Infectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, London, United Kingdom; and ∥Centre for Infectious Disease Epidemiology and Research, University of Cape Town, South Africa. Received for publication May 3, 2010; accepted July 16, 2010. The authors K.K. and S.D.L. are funded by the Wellcome Trust, London, United Kingdom. J.L. is funded by the Consortium to Respond Effectively to the AIDS TB Epidemic, who received funding from the Bill and Melinda Gates foundation. R.W. is funded in part by the National Institutes of Health through a CIPRA grant 1U19AI53217-01 and RO1 grant (A1058736-01A1). No conflicts of interest to declare. The authors K.K. designed the study, collected the data, and wrote the article with input from N.F., J.L., J.Z., C.O., S.D.L. and R.W.; K.K. designed and did the statistical analyses with input from J.L. and N.F; J.Z. and C.O. oversaw the field site; and R.W. was responsible for research infrastructure. All authors contributed to and approved the final version of the article. Correspondence to: Katharina Kranzer, Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory 7925Cape Town, South Africa (e-mail: email@example.com). JAIDS Journal of Acquired Immune Deficiency Syndromes: November 1st, 2010 - Volume 55 - Issue 3 - p e17-e23 doi: 10.1097/QAI.0b013e3181f275fd Free Metrics Abstract Objective: To investigate antiretroviral treatment (ART) interruption in a long-term treatment cohort in South Africa. Methods: All adults accessing ART between 2004 and 2009 were included in this analysis. Defaulting was defined as having stopped all ART drugs for more than 30 days. Treatment interrupters were patients who defaulted and returned to care during the study, whereas loss to follow-up was defined as defaulting and not returning to care. Kaplan-Meier estimates and Poisson regression models were used to analyze rates and determinants of defaulting therapy and of treatment resumption. Results: Overall rate of defaulting treatment was 12.8 per 100 person-years (95% confidence interval: 11.4 to 14.4). Risk factors for defaulting were male gender, high baseline CD4 count, recency of ART initiation, and time on ART. The probability of resuming therapy within 3 years of defaulting therapy was 42% (event rate = 21.4 per 100 person-years). Factors associated with restarting treatment were female gender, older age, and time since defaulting. Conclusions: Defaulting treatment need not be an irreversible event. Interventions to increase retention in care should target men, less immunocompromised patients, and patients during the first 6 months of treatment. Resumption of treatment is most likely within the first year of interrupting therapy. INTRODUCTION Access to antiretroviral therapy (ART) has improved substantially in resource-limited settings in Africa, Asia, and South America where 90% of people with HIV/AIDS reside. According to World Health Organization (WHO) estimates, more than 4 million people with HIV/AIDS in low-income and middle-income countries had initiated treatment by the end of 2008.1 Despite this success, ensuring that patients remain in care over time remains one of the major challenges in resource-limited settings. Much attention has been paid to patient adherence,2-5 loss to follow-up, and mortality in ART programs in resource-limited settings.6-9 A systematic review of 33 patient cohorts from 13 African countries reported that only between 46% and 85% of patients remained in care at 2 years.8 The realization that a substantial proportion of patients reported as lost to follow-up may have died has led to concern that there may be significant biases in program outcome reports of survival.10 Another potential source of bias is the fact that a proportion of patients may only transiently default, returning to care at a later stage. Such unstructured treatment interruption has been reported to occur in around 20% of patients in industrialized settings.11-14 The proportion of patients who transiently interrupt treatment in resource-limited settings is largely unreported. Treatment interruptions, planned or otherwise, have been found to increase the risk of opportunistic infection and death,15-17 with viral load increase and associated CD4 decline most pronounced in the first 2 months.16,18-20 Interruptions raise similar concerns with respect to drug resistance and increased mortality as suboptimal adherence.11,15,21-23 However, few studies have addressed the issue of unstructured treatment interruptions in resource-limited settings. The aim of this study was to investigate the frequency and risk factors of defaulting treatment and identify factors associated with subsequent return to care in a long-term treatment cohort in South Africa. METHODS Study Site and Data Collection The study was based in a periurban township in the greater area of Cape Town, with a population of approximately 15,000 people and an estimated adult HIV prevalence of 23% in 2005.24 The community is served by a single public-sector primary care clinic which provides ART free of charge. ART provision began in 2004. From 2005 to 2009, ART services were partly provided according to the antiretroviral treatment protocol of the Western Cape and partly through a study funded by the National Institutes of Health (NIH). Patients enrolled in the NIH-funded study could access ART with a CD4 count below 350 cells per microliter or WHO stage 3 disease as compared with 200 cells per microliter or WHO stage 4 disease in the provincial program. The NIH-funded study completed enrollment in 2007 after which all patients were treated in the provincial ART program. Initial evaluation for ART eligibility included medical history, physical examination, and CD4 cell count. A follow-up appointment was scheduled 1-2 weeks later when the laboratory results were reviewed, and ART eligibility was determined. Patients eligible for ART underwent 3 adherence counseling sessions before starting treatment. The initial follow-up schedule for those starting ART included 1 visit 2 weeks after ART initiation, followed by monthly visits until month 3. Patients who were stable on ART and did not experience any adherence problems were thereafter seen every 3 months. Three attempts were made to contact patients who had missed appointments. All patients aged ≥15 years accessing ART in the primary health care clinic between March 01, 2004, and December 31, 2009, were included in the analysis. Sociodemographic and clinical data at baseline and laboratory data were collected prospectively using a standardized data form. All laboratory tests were performed by the National Health Laboratory Services in Cape Town. Definitions "Patients defaulting treatment" were defined as those who had not presented at the pharmacy for ART refills for more than 30 days. This category included patients who subsequently returned to care and restarted ART (treatment interrupters) and patients who had not returned to care at the time of censoring (loss to follow-up) (Fig. 1).FIGURE 1: Flow chart of patients in care, first time defaulters and treatment interrupters. *Defaulting treatment was defined as having stopped all ART drugs for more than 30 days. This category included patients who subsequently returned to care and restarted ART (treatment interrupters) and patients who had not returned to care at the time of censoring (loss to follow-up). †Loss to follow-up was defined as stopping ART for more than 30 days and not returning to care at the time of censoring. ‡Treatment interruption was defined as a patient-initiated episode of more than 30 days of stopping ART and subsequently resuming treatment.Treatment interruption was defined as a patient-initiated episode of more than 30 days of stopping ART (same definition as defaulting) but who subsequently resumed treatment (Fig. 1). "Patients lost to follow-up" were those who stopped ART for more than 30 days and had not returned to care at the time of censoring (Fig. 1). Study Design In-program data on death, transfers outs, and loss to follow-up were collected prospectively. Death on ART was defined as any death within 3 months of drug refill. If the exact date of death was not recorded, it was estimated to be the 15th of the month after the last clinic appointment. Patients who had stopped ART for more than 30 days and resumed therapy were identified using the pharmacy dispensing data. The electronic pharmacy dispensing system records each time medication is dispensed to a patient. Treatment interruption was verified through folder reviews. The first endpoint was the time from ART initiation to the first time at which all drugs were stopped for a period of at least 30 days (default). Follow-up of patients on continuous therapy was censored at the date of death, date of transfer, or study end (December 31, 2009). The second endpoint was treatment resumption, defined as the time from defaulting treatment for the first time to the time of restarting ART. Follow-up of patients for whom therapy was not resumed was censored at the date of death, date of transfer, date of migration, or study end. For a proportion of these patients (48%) vital status, date of death, date of transfer, and date of migration was determined by home visits. Statistical Analysis All analyses were carried out using Stata version 10.0 (Stata Corp LP, College Station, TX). Frequency tables were produced for all categorical baseline characteristics. For continuous baseline characteristics, the median and interquartile ranges were reported. Standard survival analysis methods, including Kaplan-Meier estimates and Poisson regression models, were used to analyze the rate and determinants of defaulting therapy and of treatment resumption after defaulting treatment for the first time. The proportional hazards assumption for potential interaction between each variable and time was tested using the likelihood ratio test. A univariate Poisson regression model was used to determine risk for time-to-event outcomes for each exposure variable. Multivariate models were built through backwards elimination. Sensitivity analyses were conducted excluding individuals with unascertained vital status. All reported P values are exact and 2-tailed, and for each analysis, P < 0.05 was considered significant. Ethical Approval The study was approved by the University of Cape Town Ethics Committee and the London School of Hygiene and Tropical Medicine Ethics Committee. Written informed consent was obtained from all patients at enrollment. RESULTS Patient Characteristics A total of 1154 patients were included in the analysis (Table 1), and the median time of follow-up was 1.45 years [interquartile range (IQR): 0.48-3.24]. The majority of patients were young women (65.2%) and residents in the township (95.5%). Before treatment initiation, the majority of patients were in WHO clinical stage 3 (51.1%) and 4 (25.1%), and median CD4 count was 122 cells per microliter (IQR: 54-190). The number of patients initiating ART per year doubled from 137 in 2004 to 279 in 2006 and declined thereafter.TABLE 1: Baseline Characteristics of Patients (n = 1154) Who Enrolled in the ART Program Between 2004 and 2009A total of 291 patients defaulted treatment at least once (Fig. 1). Among these, 96 resumed therapy (treatment interruption), whereas 195 did not resume therapy during follow-up (lost to follow-up). Of the 96 individuals resuming therapy, 75 individuals had 1 episode of treatment interruption, 19 had 2, and 2 had 3. The median time patients failed to receive ART was 228 days (IQR: 126-409) during the first episode of treatment default and 194 days (IQR 121-278) during the second episode. Thirty-five patients who had stopped treatment underwent rescreening that included clinical assessment, laboratory tests, and adherence counseling and yet did not resume therapy during the period of the study. Subsequent analyses investigated first episode of treatment interruption by analyzing the time to stopping treatment for the first time and resuming therapy thereafter. Factors Associated With the Probability of Defaulting Treatment The overall rate of treatment default for the first time was 12.8 per 100 person-years [95% confidence interval (CI): 11.4 to 14.4]. The Kaplan-Meier estimate of the probability of defaulting treatment for at least 30 days was 14.9% (95% CI: 12.7 to 17.4) by 1 year, 25.6% (95% CI: 22.7 to 28.8) by 2 years and 41.0% (95% CI: 37.0 to 45.3) by 5 years from ART initiation (Fig. 2).FIGURE 2: Kaplan-Meier plot showing the probability of not defaulting ART from the time of initiating ART up to the end of the fifth year of treatment.Factors associated with increased risk of defaulting therapy in univariate analysis were male gender, higher baseline CD4 count, recency of ART initiation, and shorter duration on ART (Table 2). Defaulting rate was highest in the first 6 months of ART (18.2 per 100 person-years, 95% CI: 14.7 to 22.5) but decreased thereafter and had more than halved after 2 years (8.8 per 100 person-years, 95% CI: 7.0 to 11.0).TABLE 2: Risk Factors for Defaulting TreatmentGender, baseline CD4 count, time on ART, and date of initiation remained significantly associated with defaulting in the multivariate model. Men were 1.51 (95% CI: 1.18 to 1.93) times more likely to default treatment compared to women, as were those patients with a higher baseline CD4 count. The adjusted risk of defaulting treatment increased by 1.30 (95% CI: 1.17 to 1.44) for each calendar year. Patients on treatment for more than 2 years had a lower risk of 0.69 (95% CI: 0.48 to 0.98) of defaulting compared with patients during the first 6 months of treatment. Similar results were found in a sensitivity analysis that excluded individuals whose vital status could not be ascertained. Factors Associated With the Probability of Resuming Therapy A total of 291 patients defaulted treatment at least once. The overall rate of treatment resumption after defaulting treatment for the first time was 21.4 per 100 person-years (95% CI: 17.5 to 26.2) (Fig. 3). The Kaplan-Meier cumulative estimate of the probability of treatment resumption was 26.7% (95% CI: 21.7 to 32.7) in the first year, 37.1% (95% CI: 31.1 to 43.9) in the second year, and 42.1% (95% CI: 35.2% to 49.7%) in the third year after stopping treatment.FIGURE 3: Kaplan-Meier plot showing the probability of resuming ART from the time of defaulting therapy up to 3 years after defaulting treatment.In univariate analysis a greater likelihood of resuming ART was associated with older age and shorter time since defaulting (Table 3); gender, residency, calendar year of defaulting, and CD4 count nearest to the time of defaulting was not associated with resuming treatment.TABLE 3: Risk Factors for Resuming Treatment After DefaultingIn multivariate analysis, men were less likely to resume treatment compared with women (incidence risk ratio [IRR]: 0.67, 95% CI: 0.43 to 1.04, P = 0.07); whereas patients >30 years old were more likely to restart treatment (IRR: 1.80, 95% CI: 1.13 to 2.89). The likelihood of resuming treatment decreased significantly beyond one year of defaulting treatment (IRR: 0.40, 95% CI: 0.25 to 0.63). Of the 96 patients resuming therapy, 86 had a CD4 count measurement while receiving therapy and before the treatment interruption; the majority of these (80) responded to ART with an increase in CD4. Patients who resumed therapy were found to have a median CD4 count (150.5 cells/μL, IQR: 73-266) comparable to their baseline CD4 count before initiating therapy (138.5 cells/μL, IQR: 73-188). The median time between the measurement of CD4 count and resuming therapy was 13 days (IQR: 0-28 days). Excluding individuals with unascertained vital status revealed similar results with regards to parameter estimated, but the association with male gender became nonsignificant (incidence risk ratio: 0.81, 95% CI: 0.52 to 1.26, P = 0.35). DISCUSSION To our knowledge, this is the first study from sub-Saharan Africa to report on unstructured treatment interruptions in a routine program setting. Our analysis shows that treatment interruption is a common phenomenon. The probability of ART defaulters to resume therapy within 3 years was 42%. Most ART cohorts report on loss to follow-up, defined as not attending the clinic for more than 3 months,8 and assume that loss to follow-up is an irreversible event. Our study shows that patients who fulfill the widely used definition of loss to follow-up at one time point might resume therapy later. In this cohort, the median duration of the first treatment interruption was 7.5 months. The median CD4 count of those resuming therapy was similar to their initial CD4 count before starting treatment, which underscores the potentially negative impact of interruption leading to a reversal in immunological recovery made although on treatment. Data from industrialized settings suggest that treatment interruption has detrimental effects on CD4 count, viral load suppression, and clinical progression.11,12,19 Programs that report patient attrition and the number of patients in care will not account for the potential that up to 14% of patients in care have interrupted treatment at least once. We were able to determine risk factors for defaulting ART and factors associated with resuming therapy. Male gender, high baseline CD4 count, recency of ART initiation, and the first 6 months of treatment were associated with a higher risk of defaulting. Treatment resumption was more likely in women, patients elder than 30 years and within the first year of stopping therapy. Our finding that men were at higher risk of defaulting treatment and less likely to resume treatment is consistent with studies showing that HIV-infected men are less likely to access treatment,25,26 have an increased risk for loss to follow-up in the pretreatment period,27 present with more advanced stages of HIV disease,28 and have a higher mortality risk on ART.2,9,29-33 Strategies to diagnose HIV in men earlier and to link and to retain them in care might include the following: (1) extending clinic hours into evenings and weekends, (2) training male health care staff and counsellors, (3) offering additional adherence sessions to men, and (4) initiating male support groups. Individuals initiating treatment in more recent years were more likely to default, suggesting that programatic factors might influence retention in care. A study including data from 15 treatment cohorts from Africa, Asia, and South America showed that early patient losses were increasingly common when programs were scaled up.6 Increasing cohort size in an environment of scarce human resources for health has been suggested to influence both the scale-up capacity and the long-term retention in ART programs.34 In the study, clinic resources and staffing were further reduced when enrolment for the NIH-funded study finished in 2007. In contrast, year of defaulting was not associated with resumption of treatment, suggesting that patient tracing was less influenced by cohort size (although this would vary according to tracing procedures). Treatment defaulting was more likely in patients with less advanced immunodeficiency at baseline. This may be explained by the fact that individuals who default treatment and stay alive do so because they feel better on treatment, a phenomenon that has been reported by other studies.35 This finding is particularly important in view of the 2009 WHO guidelines recommending ART initiation at CD4 counts below 350 cells per microliter36 and when considering initiation of ART regardless of CD4 count as proposed in the "test and treat" strategy.37 Initiating ART at the time of HIV diagnosis will result in increased numbers of relatively immunocompetent individuals on ART who may have a higher risk of defaulting treatment. Specific interventions aimed at these individuals need to be developed to ensure optimal retention in care. This study has several limitations. First, ascertainment of vital status for treatment defaulters was incomplete, which may have led to a misclassification of deaths as defaulters. However, sensitivity analysis excluding individuals with unascertained vital status did not influence our overall findings. Second, resumption of therapy was not ascertained in patients who moved to other communities, possibly resulting in underestimation of treatment resumption. Third, the clinical and immunological consequences of treatment interruption were not analyzed due to lack of laboratory data, in particular, the lack of capacity to perform routine viral load, and the small number of individuals resuming therapy. However it has been shown in industrialized settings that treatment interruption impacts negatively on CD4 count, viral load suppression, and clinical progression.11,12,19 We consider that the main finding of this study that a considerable proportion of treatment defaulters return to care is likely to be generalizable to similar settings. Nevertheless, risk factors for defaulting and resuming therapy might differ with regards to eligibility criteria and resources available for patient tracing. A strength of this study is that the relatively large sample size and follow-up time. This allows for an assessment of risk factors for defaulting and treatment interruption that in turn allows for several proposals to be made to limit defaulting and treatment interruption in similar programme settings. In particular, interventions to keep patients in care should be targeted at men, patients with higher CD4 counts and during the first 6 months of ART. Moreover, the finding that the probability of resuming therapy was highest in the first year after treatment defaulting suggests that efforts to bring patients back into care might be most successful early into defaulting treatment. ACKNOWLEDGMENT The authors gratefully acknowledge the dedicated staff of the ART clinic and the Desmond Tutu HIV Centre in particular Dr. Philip Ginsberg and Carl Morrow.REFERENCES 1. World Health Organization. Towards Universal Access: Scaling Up Priority HIV/AIDS Interventions in the Health Sector: Progress Report 2009. Geneva, Switzerland: World Health Organization; 2009. Available at: http://www.who.int/hiv/pub/tuapr_2009_en.pdf last. Accessed April 16, 2010. Cited Here 2. Mills EJ, Nachega JB, Bangsberg DR, et al. Adherence to HAART: a systematic review of developed and developing nation patient-reported barriers and facilitators. PLoS Med. 2006;3:e438. Cited Here 3. Nachega JB, Mills EJ, Schechter M. Antiretroviral therapy adherence and retention in care in middle-income and low-income countries: current status of knowledge and research priorities. Curr Opin HIV AIDS. 2010;5(1):70-77. Cited Here 4. Karcher H, Omondi A, Odera J, et al. Risk factors for treatment denial and loss to follow-up in an antiretroviral treatment cohort in Kenya. Trop Med Int Health. 2007;12:687-694. Cited Here 5. Orrell C, Bangsberg DR, Badri M, et al. Adherence is not a barrier to successful antiretroviral therapy in South Africa. AIDS. 2003;17:1369-1375. Cited Here 6. Brinkhof MW, Dabis F, Myer L, et al. Early loss of HIV-infected patients on potent antiretroviral therapy programmes in lower-income countries. Bull World Health Organ. 2008;86:559-567. Cited Here | PubMed 7. Brinkhof MW, Pujades-Rodriguez M, Egger M. Mortality of patients lost to follow-up in antiretroviral treatment programmes in resource-limited settings: systematic review and meta-analysis. PLoS One. 2009;4:e5790. Cited Here 8. Rosen S, Fox MP, Gill CJ. Patient retention in antiretroviral therapy programs in sub-Saharan Africa: a systematic review. PLoS Med. 2007;4:e298. Cited Here 9. Lawn SD, Harries AD, Anglaret X, et al. Early mortality among adults accessing antiretroviral treatment programmes in sub-Saharan Africa. AIDS. 2008;22:1897-1908. Cited Here | PubMed 10. Bisson GP, Gaolathe T, Gross R, et al. Overestimates of survival after HAART: implications for global scale-up efforts. PLoS One. 2008;3:e1725. Cited Here 11. Holkmann Olsen C, Mocroft A, Kirk O, et al. Interruption of combination antiretroviral therapy and risk of clinical disease progression to AIDS or death. HIV Med. 2007;8:96-104. Cited Here 12. Touloumi G, Pantazis N, Antoniou A, et al. Highly active antiretroviral therapy interruption: predictors and virological and immunologic consequences. J Acquir Immune Defic Syndr. 2006;42:554-561. Cited Here 13. Taffe P, Rickenbach M, Hirschel B, et al. Impact of occasional short interruptions of HAART on the progression of HIV infection: results from a cohort study. AIDS. 2002;16:747-755. Cited Here 14. d'arminio Monforte A, Cozzi-Lepri A, Phillips A, et al. Interruption of highly active antiretroviral therapy in HIV clinical practice: results from the Italian Cohort of antiretroviral-naive patients. J Acquir Immune Defic Syndr. 2005;38:407-416. Cited Here 15. Seminari E, De Silvestri A, Boschi A, et al. CD4+ guided antiretroviral treatment interruption in HIV infection: a meta-analysis. AIDS Rev. 2008;10:236-244. Cited Here 16. El-Sadr WM, Lundgren JD, Neaton JD, et al. CD4+ count-guided interruption of antiretroviral treatment. N Engl J Med. 2006;355:2283-2296. Cited Here | PubMed 17. Mugyenyi P, Walker A, Hakim J, et al. Fixed duration interruptions are inferior to continuous treatment in African adults starting therapy with CD4 cell counts <200 cells/microl. AIDS. 2008;22:237-247. Cited Here | PubMed 18. Skiest DJ, Morrow P, Allen B, et al. It is safe to stop antiretroviral therapy in patients with preantiretroviral CD4 cell counts >250 cells/microL. J Acquir Immune Defic Syndr. 2004;37:1351-1357. Cited Here 19. Poulton MB, Sabin CA, Fisher M. Immunological changes during treatment interruptions: risk factors and clinical sequelae. AIDS. 2003;17:126-128. Cited Here 20. Sungkanuparph S, Kiertiburanakul S, Apisarnthanarak A, et al. Rapid CD4 decline after interruption of non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy in a resource-limited setting. AIDS Res Ther. 2007;4:26. Cited Here 21. Oyugi JH, Byakika-Tusiime J, Ragland K, et al. Treatment interruptions predict resistance in HIV-positive individuals purchasing fixed-dose combination antiretroviral therapy in Kampala, Uganda. AIDS. 2007;21:965-971. Cited Here 22. Bansi LK, Benzie AA, Phillips AN, et al. Are previous treatment interruptions associated with higher viral rebound rates in patients with viral suppression? AIDS. 2008;22:349-356. Cited Here 23. Parienti JJ, Das-Douglas M, Massari V, et al. Not all missed doses are the same: sustained NNRTI treatment interruptions predict HIV rebound at low-to-moderate adherence levels. PLoS ONE. 2008;3:e2783. Cited Here 24. Wood R, Middelkoop K, Myer L, et al. Undiagnosed tuberculosis in a community with high HIV prevalence: implications for tuberculosis control. Am J Respir Crit Care Med. 2007;175:87-93. Cited Here 25. Remien RH, Chowdhury J, Mokhbat JE, et al. Gender and care: access to HIV testing, care, and treatment. J Acquir Immune Defic Syndr. 2009;51(Suppl 3):S106-S110. Cited Here 26. Muula AS, Ngulube TJ, Siziya S, et al. Gender distribution of adult patients on highly active antiretroviral therapy (HAART) in Southern Africa: a systematic review. BMC Public Health. 2007;7:63. Cited Here 27. Amuron B, Namara G, Birungi J, et al. Mortality and loss-to-follow-up during the pre-treatment period in an antiretroviral therapy programme under normal health service conditions in Uganda. BMC Public Health. 2009;9:290. Cited Here | PubMed 28. Cornell M, Myer L, Kaplan R, et al. The impact of gender and income on survival and retention in a South African antiretroviral therapy programme. Trop Med Int Health. 2009;14:722-731. Cited Here 29. MacPherson P, Moshabela M, Martinson N, et al. Mortality and loss to follow-up among HAART initiators in rural South Africa. Trans R Soc Trop Med Hyg. 2009;103:588-593. Cited Here 30. Zachariah R, Harries K, Moses M, et al. Very early mortality in patients starting antiretroviral treatment at primary health centres in rural Malawi. Trop Med Int Health. 2009;14:713-721. Cited Here 31. Sieleunou I, Souleymanou M, Schonenberger AM, et al. Determinants of survival in AIDS patients on antiretroviral therapy in a rural centre in the Far-North Province, Cameroon. Trop Med Int Health. 2009;14:36-43. Cited Here 32. Manosuthi W, Chaovavanich A, Tansuphaswadikul S, et al. Incidence and risk factors of major opportunistic infections after initiation of antiretroviral therapy among advanced HIV-infected patients in a resource-limited setting. J Infect. 2007;55:464-469. Cited Here 33. Nachega JB, Hislop M, Dowdy DW, et al. Adherence to highly active antiretroviral therapy assessed by pharmacy claims predicts survival in HIV-infected South African adults. J Acquir Immune Defic Syndr. 2006;43:78-84. Cited Here 34. Assefa Y, Van Damme W, Hermann K. Human resource aspects of antiretroviral treatment delivery models: current practices and recommendations. Curr Opin HIV AIDS. 2010;5(1):78-82. Cited Here 35. Dahab M, Charalambous S, Hamilton R, et al. "That is why I stopped the ART": patients' & providers' perspectives on barriers to and enablers of HIV treatment adherence in a South African workplace programme. BMC Public Health. 2008;8:63. Cited Here 36. World Health Organization. Rapid Advice: Antiretroviral Therapy for HIV Infection in Adults and Adolescents. Geneva, Switzerland: World Health Organization; 2009. Available at: http://www.who.int/hiv/pub/arv/rapid_advice_art.pdf. Accessed March 2010. Cited Here 37. Granich RM, Gilks CF, Dye C, et al. Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model. Lancet. 2009;373:48-57. Cited Here Keywords:antiretroviral; Africa; HIV; loss to follow-up; unstructured treatment interruption © 2010 Lippincott Williams & Wilkins, Inc.View full article text


text:
ROYAL ASTRONOMICAL SOCIETY OF CANADA PLANETARY SECTION Bulletin No 4 July 17, 1962. PROGRESS The following additions and alterations have been made to the list of REPORT planetary contacts since Bulletin No 3 was published: Centre Contact Address Calgary Jim Wright 218 Fourth Ave. N.E., Calgary, Alta Edmonton Rickey Salmon 10341 117 Ave., Edmonton, Alta Montreal Geoffrey Gaherty, Jr 2800 Bill Park Rd, Montreal 25, Que. Ottawa Bill Day 2647 Ayers Ave., Ottawa 1, Ont. Vancouver Terry Taylor 3229 V. Third Ave., Vancouver 8, B.C. Mr B. F. Drew of the Regina Astronomical Society has agreed to act as my contact with that group. Also, one of our unattached members in the U.S., Mr Rodger W. Gordon of Pen Argyl, Pa, has been submitting observations. The change in my own address indicated is effective immediately. Enclosed are sample copies of Forms 1-J and 3, as well as a two-page sheet describing the use of Forms 2 and 3. As with the forms distributed earlier, additional copies are yours for the asking. SATURN Due to personal circumstances, this Bulletin is being sent out rather later than I had hoped. Although the event is only a few days away, I would like to ask that a special effort be made to observe the occultation of the star B.D.-19°5925 by Saturn on the night of July 22/23 predicted on p.60 of the Handbook. Notes should be made on the times of contact and on any fluctuations in the star's brightness during its passage behind the rings. JUPITER Early observations indicate great changes in the giant planet's appearance since it was lost to sight last year. Both components of the SEB seem to have been rejuvenated while the NTB remains invisible. There is a striking contrast between the extreme duskiness of the EZ and the brilliance of the STrZ, the latter making the ES a most conspicuous object in small telescopes. With Jupiter moving into the evening sky, I look forward to receiving observational reports in increasing quantities. VENUS Both Toronto and Montreal Centres are engaged in active Venus programs. I will endeavor to make any observations submitted to me available to Len Chester and Klaus Brasch who are co-ordinating these programs for their respective Centres. It is usually best to view Venus while the Sun is still above the horizon; against a dark sky the contrast of the brilliant planet will wash out any detail, which is very indefinite at best. SUBMISSION OF Ideally, I would like to receive copies of all observations made by our OBSERVATIONS members. This should pose no problems in the case of quantitative observations (transits, satellite phenomena, etc.) since carbon copies are more than adequate for my purpose. On the other hand there is no easy method of copying pencil drawings. The most common way is to make tracings of major detail with a light-box end then fill in the finer detail by hand; with care an almost identical copy can be produced. Photographic copies have also been suggested, and several Centres are experimenting along these lines. Since this is one of the most serious difficulties facing us at present, I would appreciate hearing any ideas which you might have on this subject. Geoffrey Gaherty, Jr, National Co-ordinator, Planetary Section, Standing Committee on Observational Activities. 2800 Hill Park Road, Montreal 25, Quebec. Tel.: 514-932-7485.
Planetary Section Bulletin No. 4
Other Bulletins


text: Matthew Palmer wrote: > As a kind of an adjunct to the other discussion on PHP libraries, what about > PHP programs? Not quite so touchy, as I can't see a single way forward here > (and there's no blazingly obvious reason to do so). So what are people's > best thoughts on the matter? Most packages I've seen put their > web-accessible content in /usr/share/<package>, then either set up a > separate apache config and include it from the main apache config > (phpgroupware does it this way, for one example) while other packages modify > apache.conf more intrusively. I'm a fan of the phpgroupware method, which > at least minimises pain. The best thing would probably to split such a package properly: /etc/$package/ for an apache.conf file and package configuration /usr/share/$package/root/ for the DocumentRoot for this package /usr/share/$package/include/ for additional include files[1] /usr/share/$package/data/ for additional data files /usr/share/doc/$package/ for documentation Since PHP files, include files and data files are not arch-specific, static and belong to a package they should be placed inside of the /usr directory and not inside the /var directory A PHP package should not install or link into /var/www directly since that's where the user/admin most likely places his own web pages. I won't feel very happy if random PHP packages would install themselves inside of existing web space, especially if they are likely to be used with a virtual host on their own. > But what if people are using a different Web server? It's possible, so why > are we blindly assuming apache? Should we cater for the default, and anyone > doing differently should know enough to fix the problem themselves? That's > a possibility. I'd say, include an apache.conf because Apache is the most widely used webserver that runs PHP. You'd probably be very kind if you would include configuration snippets for all available web servers, though, I wonder if it's worth the effort. > And what about where in the docroot we put our program for accessability? In general it should not matter since you should probably use relative pathnames within the namespace of the particular package. Hence if it is installed in /, the files are referenced as /foo.php, however, if they're mapped into the web server as /bar/, then all files will be referenced as /bar/foo.php. Since the user needs to map the package into his own namespace, either in his main web space in /var/www or into one of his virtual hosts, but that's really an issue of the user. I don't think a package could find out all possibilities of Apache configurations and (virtual) hosts configurations to add itself into the proper one. Hence, I'd say, leave it to the admin. Footnote: 1. Include files should not be executable on their own and hence should not be placed inside the web tree directly Regards, Joey -- Every use of Linux is a proper use of Linux. -- Jon "Maddog" Hall Please always Cc to me when replying to me on the lists.


text:
Dr. Zhaoxin PuFormer Research Fellow
Innovation and Entrepreneurship Research
Areas of Interest:
Economics of Innovation, Industrial Organisation, Organizational Economics, Empirical Methods
Academic Résumé
10/2015 - 07/2020
Junior Research Fellow at the Max Planck Institute for Innovation and Competition (Innovation and Entrepreneurship Research)
Doctoral Candidate at the LMU Munich Graduate School of Economics, Graduate Programme 'Evidence-Based Economics'
Doctoral Thesis: "Spillovers and Selection of Ideas – Firm-Level Evidence from Innovation Networks, Multinationals in China and Crowdfunding Platforms"
09/2012 - 08/2015
Economic Analyst, NERA Economic Consulting, London
09/2011 - 06/2012
Master Studies in Economics (M.Sc.), London School of Economics and Political Science
09/2010 - 06/2011
Consultant and Carlo-Schmid Fellow, International Trade Centre (UN/WTO), Market Research and Analysis, Geneva
07/2008 - 06/2009
Work Experience as Teaching Assistant and Student Research Assistant at the University of Mannheim and as an Intern at Allianz / Dresdner Bank Economic Research
09/2007 - 08/2010
Bachelor Studies in Economics (B.Sc.), University of Mannheim and Università Commerciale Luigi Bocconi Milan
Academic Prizes / Honours / Memberships
2011 - 2012
Haniel Scholarship from Studienstiftung des Deutschen Volkes and the Haniel Foundation for Graduate Studies at the LSE
2010 - 2011
Carlo Schmid Scholarship from the German Academic Exchange Service (DAAD) and the Studienstiftung des Deutschen Volkes for a Traineeship at the International Trade Center
2008 - 2012
Scholarship by the Stiftung der Deutschen Wirtschaft
2008 - 2009
Scholarship by the University of Mannheim and Dean's List
Discussion Papers
Max Planck Institute for Innovation & Competition Research Paper, No. 18-05. DOI(2018). Openness as Platform Strategy - Evidence from a Quasi-Experiment in Crowdfunding,
- A platform's decision to open up its marketplace is at the core of its business strategy. It needs to balance between the benefits of market thickness and the costs of potential congestion and quality concerns. We discuss how openness can increase platform value and test our hypotheses by analyzing the strategic decision of a leading crowdfunding platform to switch from access control to de facto openness. The decision increased market thickness on the previously access-controlled supply side of crowdfunding projects. The platform hereby gained market share from its main competitor. Market matches on the platform increased in absolute but not in relative terms. Moreover, quality on the supply side declined immediately, lowering platform value for demand-side users.
- Available at SSRN
meaStudies, 12. Mannheim: MEA, Mannheim Research Institute for Economics of Aging.(2015). Abhängigkeit der Pflegeversicherungsausgaben von der Entwicklung der Pflegewahrscheinlichkeiten,
Presentations and Lectures
The Unintended Effects of Intended Effects of Trade Liberalization on the Sources of Learning
TUM Workshop on Innovation, Technological Change, and International Trade
Location: Heilbronn
The Unintended Effects of Intended Effects of Trade Liberalization on the Sources of Learning
MPI Junior Researcher Workshop 'From Science to Innovation'
Location: Munich
Openness as Platform Strategy - Evidence from a Quasi-Experiment in Crowdfunding
Strategy, Entrepreneurship & Innovation (SEI) Doctoral Consortium
Location: Munich
28. - 30.06.2018
Openness as Platform Strategy - Evidence from a Quasi-Experiment in Crowdfunding
2nd EBE Summer Meeting
Location: Ammersee


text:
By Julie Ingwersen and Karl Plume - March 1 (Reuters) - Flooding and ice buildup on key rivers in the U.S. Midwest has stalled the movement of barges that supply export terminals at the Gulf of Mexico with grain and soy, barge and grain traders said. One lock on the Ohio River became impassable last week, halting vessels moving to and from the Mississippi River until as late … [Read more...]
U.S. Confirms China Soybean Purchase, But No Clarity Over More Sales
By Julie Ingwersen and Humeyra Pamuk CHICAGO/WASHINGTON Dec 13 (Reuters) - U.S. government officials on Thursday hailed China's first meager purchase of U.S. soybeans since its trade war with the United States began in July and said they hoped for, but could not guarantee, more to come. The U.S. Department of Agriculture (USDA) announced private sales of 1.13 million … [Read more...]
Spoils of Trade War: Argentina Loads Up On Cheap U.S. Soybean
By Hugh Bronstein and Karl Plume BUENOS AIRES/CHICAGO, Nov 30 (Reuters) - A ship named the Torrent is nearing the end of a 5,000-mile trip carrying soybeans from the U.S. Great Lakes to Argentina - a journey that only makes economic sense because of the U.S.-China trade war. The ship is scheduled to dock in the Rosario grains hub on Dec. 4, days after the leaders of the … [Read more...]


text:
Many secondary metabolites of plants have medicinal properties. It is their misuse that creates problems. Justify the statement with an example.
Many secondary metabolites obtained from plants are used for their'medicinal properties, e.g. opiates derived from poppy plant are used as drugs to relieve pain.
The problem starts when these metabolites are misused for having pleasure and are taken in doses above the prescribed limit, e.g. opium addict- loses wight , fertility and interest in work.


text:
Supplementary feedingstuff for all rodents and dwarf rabbits.
healthy crude feed for every day. The low-calorie taste experience from a composition of nine different herbs supports the dental abrasion, and
the well-balanced mixture of vitamins and trace elements contributes to a healthy, shiny fur. The high crude fibre content ensures optimal digestion and thus enhances the feeling of well-being.
Feeding recommendation:
Mixed with hay or other herbs; or additionally for daily hay ration.
green oat, parsley 20%, lucerne, green wheat, nettle 7.7%, melissa, dandelions, The plant life which grows on the permanent pastures of the Alpine foothills, peppermint, chamomile 2.3%
Analytical constituents:
Protein 16.9%, fat content 2.6%, Crude fibre 21.2%, Crude ashes 10.9%
250 g


text:
From American Thinker and Frontpage comes this:
There is not a whisper of this yet in the mainstream media, but there is a trail of evidence strongly suggesting that Ismaaiyl Abdullah Brinsley, the assassin of officers Liu and Ramos, was a jihadist. Daniel Greenfield of Frontpagemag. com discovered on his Facebook page a shot of the Koran with a telling verse on jihad:
Against them make ready your strength to the utmost of your power, including steeds of war, to strike terror into (the hearts of) the enemies, of Allah and your enemies, and others besides, whom ye may not know, but whom Allah doth know. Whatever ye shall spend in the cause of Allah, shall be repaid unto you, and ye shall not be treated unjustly. (emphasis added)
Intrepid jihad researched Patrick Poole has also uncovered evidence on Brinsley's Instagram trail indicating he may have visited a notorious mosque in Brooklyn:
Responding to a comment on his message, he notes that he is headed to "Al-Farooq Tomorrow inshallah." His social media traffic indicates that he transited from Atlanta, Baltimore and Brooklyn on a regular basis.
If this reference by the cop killer was from Brooklyn (which is hard to discern since his Instagram account has been taken down), it may indicate that he was going to visit Masjid Al-Farooq in Brooklyn.
Al-Farooq's long history of terror support goes back more than 20 years, when the 1993 World Trade Center bombing was hatched by members. One imam from the early 1990s, when Al-Farooq was a hub of the nascent Al-Qaeda and was hosting Al-Qaeda co-founder Abdullah Azzam, was Fawaz Damra, who was charged, convicted and later deported for lying to immigration officials about his terror ties when he applied for U.S. citizenship.
Another Al-Farooq imam, Gulshair Shukrijumah, was not only a regular translator for the Blind Sheikh Omar Abdel Rahman, but his son, Adnan, became a top Al-Qaeda operative and was killed in a gun battle with Pakistani intelligence just a few weeks ago.
Yet another mosque official, Sheikh Mohammed al-Moayad, was charged in 2003 with using the mosque as a front to raise $20 million for Al-Qaeda. At the time, the New York Times noted the mosque's extensive connections to terrorism.
Poole cautions that this may not be the same Brooklyn Al-Farooq mosque. But if it is, we have another dot to connect.The enemies of ordered liberty are legion.


text:
Come and join Imperial College Iranian Society for an evening of football, supporting Iran's national team at the 2018 FIFA World Cup. Appetizers and refreshments will be served from a local Iranian restaurant.
Contact the organizer for latest event info. Kodoom.com is not responsible for any changes made in the above information. Report or Flag this event


text:
Directed by Quentin Dupieux
Dolph Springer awakens one morning to find he has lost the sole love of his life – his dog, Paul. Desperate to reunite with his best friend and to set things right, Dolph embarks on a journey which spirals into the realm of the absurd. On his quest, he drastically alters the lives of several severely bizarro characters.
Dolph Springer wakes up one morning to realize he has lost the love of his life, his dog, Paul. During his quest to get Paul (and his life) back, Dolph radically changes the lives of others -- risking his sanity all the while.
Cast: Jack Plotnick, Eric Judor, Alexis Dziena, Steve Little, William Fichtner, Regan Burns, Mark Burnham, Arden Myrin
Member Reviews
This movie 自慰 my brain.


text:
First published in 1968, four years after Ian Fleming's death, this was the first Bond 'continuation' novel, penned by one of Britain's finest novelists, Kingsley Amis.
'A man in my line of business shouldn't work to a timetable'
Lunch at Scott's, a quiet game of golf, a routine social call on his chief M – James Bond's life has begun to fall into a pattern that threatens complacency…until the sunny afternoon when M is kidnapped and his house staff savagely murdered. The action ricochets across the globe to a volcanic Greek island where, stripped of all professional aids, Bond must avert a world-menacing conspiracy and face unarmed the monstrous devices of the glacial, merciless Colonel Sun.
Keine Bewertung
Kein Eintrag


text:
What Matters To Me: Lavine Hemlani, Ed-tech Entrepreneur
In the What Matters To Me series, a Generation T honouree describes what they do, why they do it, and why it matters.
Lavine Hemlani wants to change the future. Through his ed-tech startup Xccelerate, the former Wall Street investment banker is offering individuals and companies the chance to upgrade their skills for the modern workplace. At school, most of us learned algebra, geography and history; Hemlani wants to teach people about artificial intelligence, software engineering and blockchain—and hopefully bring Hong Kong to the centre of the tech universe in the process.
A few years ago, I was working in New York, but I got tired of Wall Street. So I decided to change everything and move to Namibia to build schools. It was an incredible experience and made me realise how interested I am in teaching and the school system. After I moved back to Hong Kong, I decided to combine my two passions: education and startups.
Hong Kong is a very fast-paced city but the talent—particularly when it comes to tech—is often not up to par and this makes it difficult for companies to launch startups or hire top-quality engineers. Spotting a gap in the market, I launched Xccelerate, a learning centre for blockchain, coding and all things tech-related.
Every startup faces obstacles but, unusually, ours showed us that we were on the right track professionally. It really wasn't easy to find the right people to work for us—those who had tech experience and were diligent and talented. Through Xccelerate, this is a challenge I'm trying to solve.
I've got pretty ambitious plans for the future. In 10 years I would like us to have built an IP-centric platform that powers thousands of platforms in countries around the globe. I want to create real educational change for people in India, China and further afield.
Education is the number one driver for economic progress in a country and I don't think politicians or journalists focus on it nearly enough. Countries with amazing educational systems consistently outperform those everywhere else. Just look at Finland and the way they focus on blended and hybrid learning. It has incredible results. Currently we are not looking at what the future holds; our educational systems are under pressure as they are designed for prehistoric jobs rather than the new tech world we live in.
The best advice I can give anyone launching a startup is not to be afraid. Don't worry about failure or about making mistakes, and just embrace the idea that you will go through some pain before you experience real success; this is part of the journey. And be prepared to work really, really hard.


text:
The best decision to feed the child thoracal milk. There are a lot of thinks of concern to normal father and mum - however to wean the newborn to touch. Problem how to disaccustom a baby from the swing is very important.
How to look for the child - modern parent worries. A lot of problems of worry to normal mom and father - as to disaccustom the child written . Thinks disaccustom a child from night feeding is highly influential.
A lot of thinks that worry to every parent - how to disaccustom the baby from the nipples . Problem as to wean the child suck his thumb is very influential. Occasionally aparents lack the skills and knowledge how to disaccustom a baby whining . Sometimes extremely influential time to take leaving of a child.
Thoroughly wash a newborn in a evening. Not any better to nourish the baby breastmilk. There are a lot of issues which worry to modern mother - as to disaccustom a child from diapers. Issues as to wean a baby from a habit is very serious. Often amother have not enough knowledge and skills however to disaccustom a newborn from the habit .
From pristenochny
Bodies of the digestive and respiratory systems are called as vegetative bodies, as serve only vegetable or inactive organism aspect of life.
Only recently the last researches showed, just bodies vivatsya.
There is a following: in the uniform layers there are points, or the centers, which suddenly on chinat to show high biological activity.
From pristenochny matrixes cages are formed and start Faure to mirovaniye of body, or rudiments of body.
Irrespective of, what is body, the scheme of its emergence is always identical..
Похожие статьи
Объявления2020-Jun-18 12:06 AKaxadvannimi из [email@example.com]
buy cialis2020-Jun-23 07:06 AKaxadvannimi из [firstname.lastname@example.com]
cialis online cheap


text:
New event for Northern Rivers gourmet food lovers
A FUN new event will light up the streets of Byron Bay where a world of flavours will ignite your taste buds with over 20 gourmet food trucks from all around the region.
The front carpark of the Byron Bay Brewery will light up when it's taken over by 20 food trucks, live music and family fun entertainment.
This year's Bluesfest Busking Competition winner Tay Oskee will be providing the entertainment with his unique style of roots, folk and rock.
Sydney-based artist Harvey will continue the entertainment in the beer garden, performing coastal folk tunes.
Event parking will be at the Butler St Reserve.
Festivities will be held from 4pm-10pm on Saturday, April 29 at 1 Skinners Shoot Rd, Byron Bay.


text:
poor little guy was still not feeling well last week and i….well…i bribed him with ice cream in order to get him to do a photo shoot.
there i admitted it!
truth be told we were both tired of being in the house so i took advantage of his willingness to model for me. he took advantage of the free ice cream cone. it was a win-win situation!
i just can't resist dressing up those boys of mine. they are just so handsome…and so easily bribed.


text:
Shirt / Leggings/ Blanket/ Book
Like many of you, I am also in self-isolation at home when I'm not working due to COVID-19. Although Netflix & chill sounds like a great idea, you can only binge watch so many shows before boredom kicks in. We have a lot more free time in our hands, and there are several activities you can do to pass the time.
I've had so many projects on hold because I'm always running around or would much rather hang out with my family, fiancé, and friends. Quarantine can be the perfect excuse to practice some self-care, spending much needed time with your family, or de-cluttering your closet and drawers.
- De-Clutter Your Life
Marie Kondo is just what I needed! Out with the old, in with the new! I can't tell you how satisfying it was to clean out my closet and drawers. If you haven't worn it in six months get rid of it, you can donate it or sell it.
- Get Your Fitness On
All we have is time and setting aside 40-60 minutes a day to sweat it out and work on your fitness is a must! Plus, it'll help keep you from going stir crazy. There are so many workout apps to choose from that have tones of options to choose from, such as Tone it Up, Fitonapp, Sweat. Fitness studios like Peleton, Oranage Theory, and Pure Barre are offering free online workout classes during this time. So get ready to burn some calories and tone that body!
- Game Night with the Fam
Get those board games out and get ready for some competitive fun! If you're lucky enough to be self-isolating with your family take advantage and bring out your favorite games.
- Book Club
Time to finish reading your book that's been sitting on your nightstand for the last five months (guilty). Pour yourself a glass of wine or hot tea, get a cozy blanket, and pick up that book you've been meaning to read. There are plenty of digital book clubs!
- FaceTime with Friends
I know I'm not the only one who misses human interaction. I can't wait to hug and see all my gals and familia! Thank God for FaceTime and Zoom that allows us to set up group chats and catch up with the people we love! Comb your hair, pour your favorite drink, and get ready to get digital.
- Get Some Rest
One way to boost your immunity is to ensure you're getting at least 8 hours of sleep. Spray lavender on your pillows, use a sleeping mask, and try your best to get some sleep. I know so many American's are worried about how they are going to pay their bills, will they have a job, or when this will be over.
- Spa Day/ Night
We can all use some self- care right about now; maybe you can finally try that homemade hair or face mask. A DIY manicure and pedicure might happen soon in my living room because my no-chips are on hold until further notice, lol.
Do you guys have any ideas you would like to share?!


text:
==> Généthique.org :
"Deux médecins américains, Eli et Amy Friedman, viennent de demander la légalisation de la vente d'organes provenant de donneurs vivants. Ces spécialistes de la transplantation rénale pensent qu'il s'agit du seul moyen pour lutter contre la pénurie de donneurs et pour stopper le développement du marché noir international.
Des européens en attente de rein vont ainsi payer jusqu'à 150 000 Euros à des trafiquants pour obtenir un organe acheté en Europe de l'Est moins de 2500 Euros.
Eli et Amy Friedman proposent de créer une agence gouvernementale chargée de réguler ce marché officiel des organes. Ils suggèrent de verser 40 000 dollars à un donneur de rein".
"Selon un rapport du Conseil de l'Europe, 40 000 patients européens attendraient une transplantation rénale. 15 à 30% d'entre eux mourront faute d'avoir pu trouver un donneur".
© genethique.org
Chaque article présenté dans Gènéthique est une synthèse des articles de bioéthique parus dans la presse et dont les sources sont indiquées dans l'encadré noir. Les opinions exprimées ne sont pas toujours cautionnées par la rédaction.
==> All Things Considered, February 16, 2006.
"An article in the journal Kidney International proposes the legalization and regulation of the sale of human kidneys. One of the authors, Dr. Amy Friedman of Yale University Medical Center, explains to Robert Siegel the rationale behind this growing opinion."
==> "Junk medicine: organ donation", by Mark Henderson
"No need for a meat market
More than 5,500 British patients are waiting for a new kidney. However, the shortage of organs is such that only 1,700 of these can expect a transplant each year. More than a quarter of the lucky ones have a friend or relative to thank for their new organs. Of the less fortunate, more than one a day will die on the waiting list.
Though the NHS's transplant registry has been running for more than a decade, demand for donated organs still far outstrips supply. Only one Briton in five has recorded a wish to help someone else to live in the event of an untimely death. Too many people who would not object to donation fail to make their wishes known and many bereaved relatives are thus understandably reluctant to sanction a transplant.
The result is great human misery and significant cost to the NHS — the recipient of a kidney transplant costs between half and a third as much as a dialysis patient over five years.
This week, two American doctors suggested that society address this problem by thinking the unthinkable.
In the journal Kidney International, Eli Friedman, of the State University of New York, and Amy Friedman, of Yale University, proposed that medicine break down a great taboo and consider a regulated market in organs sold by the living.
Permitting the sale of kidneys would ensure that paid donors received a fair price — the paper suggests $40,000 (£23,000). The cost could be financed by savings on dialysis. Legalisation would also clean up a murky field, in which rich 'transplant tourists' travel to developing countries for new organs.
Friedman and Friedman compare the sale of a kidney to surrogate motherhood and sperm and egg donation, for which payment is permitted in the US, though not in Britain. But while their paper is thought-provoking, it goes too far. Their analogy with reproductive medicine is a false one — a sperm donor parts with nothing that threatens his health, while the risks of egg donation and surrogacy are trivial when compared with the loss of a kidney.
The best response to the existence of a black market that exploits the poor is not necessarily to accept it. To institutionalise the sale of organs might improve the medical care of paid donors but at a cost of encouraging the vulnerable to mutilate themselves for money.
It is not a price worth paying, particularly as there is a simple and proven solution to the organ shortage that has none of the drawbacks of paid donation. This is to adopt a policy of 'presumed consent', by which everybody is regarded as a potential donor unless they have specifically indicated otherwise. Where Britons opt into the donor system, citizens of Spain, Belgium and Austria must opt out.
The experience of these countries suggests that presumed consent makes a vast difference. Those with objections to transplantation, such as Jehovah's Witnesses, have their rights protected. The deceased's next-of-kin can still refuse permission but the assumption in favour of donation makes this less likely in practice. In Britain, almost half the relatives of potential donors refuse to release their organs. In Spain, the rate is just 24 per cent.
Spanish waiting lists for new organs have halved since the system was changed ten years ago.
Yet when presumed consent was proposed to Parliament in 2004, with the backing of the British Medical Association, it fell under a government three-line whip. A squeamishness about organs and consent — the legacy of the Alder Hey affair — has strangled a perfectly ethical measure that would alleviate much suffering, while saving scarce funds.
The dead — and, for that matter, their families — have no call for kidneys and livers. Until this source of organs for transplants is maximised with presumed consent, the kidney of a living person will remain an unethical purchase."
Mark Henderson is the Times science correspondent
© TimesOnline.co.uk
Merci de ne PAS poster de messages concernant la vente d'un organe et comportant des coordonnées téléphoniques, e-mail, etc. La loi française interdit la vente d'organes.
Un marché pour légaliser la vente d'organes ?
Aucun commentaire:
Inscription à : Publier les commentaires (Atom)