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Hosea Announces Punishment for Israel
1People of Israel, stop celebrating your festivals like pagans. You have turned away from your God and have been unfaithful to him. All over the land you have sold yourselves like prostitutes to the god Baal and have loved the corn you thought he paid you with! 2But soon you will not have enough corn and olive oil, and there will be no wine. 3The people of Israel will not remain in the LORD's land, but will have to go back to Egypt and will have to eat forbidden food9.3 forbidden food: The Law of Moses prohibited the eating of certain foods as being ritually unclean (see Lev 11). in Assyria. 4In those foreign lands they will not be able to make offerings of wine to the LORD, or bring their sacrifices to him. Their food will defile everyone who eats it, like food eaten at funerals. It will be used only to satisfy their hunger; none of it will be taken as an offering to the LORD's Temple. 5And when the time comes for the appointed festivals in honour of the LORD, what will they do then? 6When the disaster comes and the people are scattered, the Egyptians will gather them up — gather them for burial there at Memphis! Their treasures of silver and the places where their homes once stood will be overgrown with weeds and thorn bushes.
79.7: Lk 21.22The time for punishment has come, the time when people will get what they deserve. When that happens, Israel will know it! "This prophet," you say, "is a fool. This inspired man is insane." You people hate me so much because your sin is so great. 8God has sent me as a prophet to warn his people Israel. Yet wherever I go, you try to trap me like a bird. Even in God's Temple the people are the prophet's enemies. 99.9: Judg 19.1–30They are hopelessly evil in what they do, just as they were at Gibeah.9.9 Gibeah: At this city some Israelites of the tribe of Benjamin raped a Levite's concubine; this caused a civil war that almost wiped out the Benjaminites (see Judg 19—21). God will remember their sin and punish them for it.
Israel's Sin and its Consequences
109.10: Num 25.1–5The LORD says, "When I first found Israel, it was like finding grapes growing in the desert. When I first saw your ancestors, it was like seeing the first ripe figs of the season. But when they came to Mount Peor, they began to worship Baal, and soon became as disgusting as the gods they loved. 11Israel's greatness will fly away like a bird, and there will be no more children born to them, no more women pregnant, no more children conceived. 12But even if they did bring up children, I would take them away and not leave one alive. When I abandon these people, terrible things will happen to them."
13LORD, I can see their children being hunted down9.13 Probable text being hunted down; Hebrew unclear. and killed. 14What shall I ask you to do to these people? Make their women barren! Make them unable to nurse their babies!
The LORD's Judgement on Israel
15The LORD says, "All their evil-doing began in Gilgal. It was there that I began to hate them. And because of the evil they have done, I will drive them out of my land. I will not love them any more; all their leaders have rebelled against me. 16The people of Israel are like a plant whose roots have dried up and which bears no fruit. They will have no children, but even if they did, I would kill the children so dear to them."
The Prophet Speaks about Israel
17The God I serve will reject his people, because they have not listened to him. They will become wanderers among the nations.
Good News Translation® with Deuterocanonicals/Apocrypha (Today's English Version, Second Edition) © 1992 American Bible Society. All rights reserved. Anglicisation © The British and Foreign Bible Society 1976, 1994, 2004.
The copyright for the derivative work of Anglicisation pertains only to the text within the Good News Translation (GNT) that British and Foreign Bible Society adapted for British literary usage, consistent with Section 103(b) of the United States Copyright Act, 17 U.S.C. § 103(b).
Bible text from the Good News Translation (GNT) is not to be reproduced in copies or otherwise by any means except as permitted in writing by American Bible Society, 101 North Independence Mall East, Floor 8, Philadelphia, PA 19106-2155 (www.americanbible.org). All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording or any information storage or retrieval system, without permission in writing from the publisher.


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Merry Christmas and happy festivities !!
No poll like the last time round, or are you waiting until it's close to a certain milestone (like the debates?)
No problem ! I hope you had a awesome birthday.
Happy Birthday Ubiq!
Happy Birthday, Ubiq!
Enjoy your day with those you wanna have around you. Cheers
Happy birthday !!!
Yeah, I've been trying not to peek at the movies that have won beforehand (unseen ones, at least), so I'll try to do the same with this one.
Ahh okay. I've never seen the movie before, so the reference went right over my head, haha.
About this post... is the movie you're nominating this? Don't want to mess up when I make the poll.
air to surface missiles
The Fabulous Ronettes
check up from the neck up

subset: commoncrawl


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Burzum versus Death? Possessed versus Mayhem? Just what is the difference between black metal and death metal? Perhaps to metalheads the question is elementary, or even insulting, but to the metal novice an explanation is useful. Thankfully, our recent "What's In My Bag?" interview with Warbringer spawned an impromptu lesson. Having many a descriptive thing to say about their music and movie choices, the guys from the Newbury Park thrash metal band had no trouble enlightening us about the differences between the two sub-genres.
"Fundamentally it's this: the objective is different," starts lead singer John Kevill. "Death metal wants to basically crush shit," he says. "Black metal's this more cathartic, emotional thing."
We loved the band's "metalology" lecture so much that we turned it into its own video. In it they break down the technical, emotional, and geographical differences between the two sounds, and the different sub-genres that subsequently stem from them.
Watch Warbringer's lesson on black metal and death metal below:
Black Metal vs Death Metal with Warbringer
Watch and comment on YouTube


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Meet Jamie Parganos
Kids: Alex & Leo Age: 39 Years
CEO & Founder Jamie Parganos started Mommy Hacks with a purpose: to help mothers feel more super. In a world where moms are often overworked and undersupported, Jamie set out to create a carefully packaged toolkit to help mothers be in their power and win at parenting.
As a mom of two little ones, Jamie finds herself constantly devising hacks and clever ways to simplify or enhance everyday parenting activities like going out to eat, getting into the car, bath time, etcetera. Now, you can get these kid tested, mom approved hacks delivered straight to your doorstep.
In a culture where mom-shaming is not uncommon, where there are spaces online where moms get bashed for practicing one parenting methodology over another, Jamie saw another need: a safe space for mothers to share their knowledge and experience. So she created the Wonder Mommy blog and uses it as a platform where super moms with unique strengths are honored and uplifted.
Before founding her companies, she worked as a program director for non-profits in the New York City public school system. A mom who wears many hats, Jamie is also a professional singer. She lives in Queens with her two children, ages 3-years-old and 11 months.
Who is Wonder Mommy?
It's me. It's you. It's that woman at the deli who has a screaming toddler under one arm, is hoisting two gallons of milk onto the counter with the other, and is conducting an interview on her cellphone which is propped between her shoulder and her ear. Great Scott! This truly is a job for a superhero.
The beauty of being a Wonder Mommy is that we don't have to wear the cape all the time. In fact, I've designed Mommy Hacks to help streamline regular parenting activities so that you can be more present and engaging with your children (and with yourself, too).
If You've Ever Wondered…
How do I instill good values in my child?
How do I hold onto my full identity even when motherhood demands so much of me?
How can I "find time" to work on my career or my relationships?
Exactly when will my breasts stop hurting?
Find the answers to these questions and more on the Wonder Mommy blog!
Mommy Hacks: Tips & Hacks
Recent Blog Posts
On Becoming A Single Mom
It's been a while since I've been able to speak about being a mother. When my relationship with my children's father fell apart last summer, I felt like I had lost my family. I felt like a bad mother. I felt like I failed my children. I did everything I could to raise my children well…
What about Me? Notes from a Sibling of a Chronically Ill Child
My older brother Adam was diagnosed with Cystic Fibrosis – a chronic genetic disease that affects the lungs and digestive system – when he was a toddler. I don't remember it because I was a newborn at the time, but my mom always likes to joke about how, when they got his diagnosis, she looked…
How to Raise Boys to Become Decent Human Beings
I have two sons. I don't know much about what it's like to be a boy. I've been a woman my whole life. I certainly know what that's like. And we all know it ain't easy. When I had my sons, I came to a new realization. I don't think it's easy to be a…


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During his career as a police officer, every time Barry Ruhl thought he had heard the last of Larry Talbot, the man's name would crop up again in one investigative context or another. And no one was more surprised than Ruhl when Talbot came back into his life years after the officer had retired. This first-time writer presents his premise about Talbot in the meticulous detail of a police report and while he realizes it may never be possible to obtain justice in the cases he describes, he hopes the very act of getting his suspicions on the record may bring some measure of comfort to the families of the many women whose final hours remain a mystery.
Barry Ruhl was an Ontario Provincial Police Officer for 30 years. After his retirement, he continued to work with the OPP as a counsellor for other officers dealing with substance abuse and post traumatic stress issues. He has a BA in Sociology from University of Waterloo and a BSW (Hons.) from York University and he and his wife Pat live in a small Ontario town on the shore of Lake Huron. They have one son, Jeffrey.


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Please click here to view the video.
For almost a century, Jharia coal fields have been on fire in the Indian state of Jharkhand because of poor mining techniques. Many of the people who live on the burning fields survive by collecting coal illegally. The coal is burned and then transported to nearby markets for very little money. A resettlement plan has been put in place, but the area's residents are reluctant to move to safer grounds because the coal earns them their livelihood.
Bombay Flying Club is an independent audio-visual production house in Denmark consisting of three photojournalists. Their recently-launched Wasteland project is a series of web documentaries about industrial pollution, and the story from Jharia is the first chapter of this ongoing project.
Poul Madsen, BFC founder, has a degree in photojournalism from The Danish School of Journalism and has previously worked as a news photographer for various Danish papers and for the Indian Express in Mumbai, India. In addition to working in online journalism for the past four years, Poul also works in film documentary.
Henrik Kastenskov started out as a fashion and advertising photographer, but his craving for documenting real life stories and situations brought him to The Danish School of Journalism. Since 2006, he worked as a staff news photographer on several Danish papers before turning freelance work.
Brent Foster is an award-winning Canadian video journalist who currently resides in Delhi, India. Brent works on assignments for clients in North America and his work is often featured in Time Magazine and the Globe, and Mail.
Line Wolf Nielsen is a Danish freelance journalist residing in Delhi, India, who covers South Asia for clients in Denmark and elsewhere. Her job has brought her to Nepal, Sri Lanka, Afghanistan, Bhutan, and China.


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CMR Stampede — Oct. 31, 2019
October 31, 2019
Isabel Foley, Staff Writer
October 8, 2020
Many Americans are having trouble comprehending what exactly happened during the Oct. 6 Presidential debate. At the beginning of the debate, which took...
Student journeys to America for one year
October 8, 2020
Everything's wrong with JK Rowling's new book
October 2, 2020
David Miller, Staff Writer
October 8, 2020
Fine arts are in limbo this school year. Uncertainty over issues such as distancing performers, seating audiences, and sanitizing props and instruments...
The student news site of C. M. Russell High School
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Availability: On our shelves now at one or more of our stores
Published: Vintage - March 23rd, 2010
A marriage plot with no infidelity or emotional strife (of the humorless variety, at least) is certainly an odd duck in most domestic fiction but Colwin's novel flies in the face of convention. Illuminating the everyday humor and anxieties of married life with penetrative wit, it is a work interested in celebrating love's less pronounced colors. The characters' endless bemusement and befuddlement is an immense pleasure, revealing the innumerable ways in which we are capable of love.


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Free "Best of Bonnaroo" music for climate change
Monday, March 01, 2010
By Julie Wiegan
The Bonnaroo Music and Arts Festival is giving away free music downloads by major artists that includes Pearl Jam, Dave Matthews Band, Phish, and Jack Johnson. Best of Bonnaroo is a compilation of 17 different live performances that is available at MusicForAction.org.
Although the downloads are free, Bonnaroo is requesting that users email their Senators, the President, or their local newspapers about the issue of climate change. "This generation has an opportunity to be remembered as one that confronted environmental challenges and took responsibility for the future," said Jack Johnson. "With that opportunity comes the responsibility to speak out."
HeadCount and NRDC Action Fund have teamed up with Bonnaroo to provide the free music downloads. HeadCount, a non-partisan civic engagement organization best known for registering voters at concerts, came up with the idea. The NRDC Action Fund, an advocacy group committed to passing legislation that jump-starts the clean energy economy and reduces pollution stepped in with resources, research, strategic guidance and a base of 250,000 supporters.
"The decisions made today will affect you and your children for many years to come," said former Grateful Dead guitarist Bob Weir, a member of HeadCount's board of directors who can be heard on the compilation with has band RatDog. "Whether it's voting in an election or speaking out about issues like climate change, it's critical that we all make enough noise so that politicians have no choice but to listen."
Here is the complete list of Best of Bonnaroo track list:
Wilco Bull Black Nova
Pearl Jam Animal
Jack Johnson Inaudible Melodies
Dave Mathews Band Rapunzel
Death Cab for Cutie Cath…
Ani DiFranco Fuel
Phish Kill Devil Falls
Gov't Mule Banks of the Deep End
O.A.R. Delicate Few
moe. Not Coming Down
Raphael Saadiq 100 Yard Dash
Bob Weir & RatDog Throwing Stones
The Disco Biscuits And The Ladies Were the Rest of the Night
The Decemberists The Wanting Comes in Waves/Repaid
My Morning Jacket Oh! Sweet Nuthin'
Guster Happier
Phil Lesh and Friends Box of Rain


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It gets so cold in January and God I mind it, warm-blooded creature that I am. It turns out we humans aren't that good at cheerfully soldiering on when the temperatures really plunge.
It makes me think of something a nice young cardiologist told me he says to his patients. He tells them, "Embrace the pain," and I had to smile a little, hearing it. I mean he's a heart doctor; most of his patients are heart patients.
"How does THAT go over?" I had to ask. I needed him to explain more. "Well," he said, "you have to just accept your pain on some level. Not fight it, or curse it, or stiffen against it but sort of… open up to it instead. "
Ok I thought. Maybe the way an animal does, when confronted with the wounded paw or the bitten ear, or the fear of the unknown that arises at the sight of that examining table in the vet's office.
It's a compelling theory; I'll give him that. Not sure it works with the cold though.
Cold of the kind we have known lately sets off the body's most unignorable alarm bells. "Danger to the Organism!" it says, the direst message the body can send.
Because cold is the enemy, plain and simple.
These days I pity every cold thing I see out there, except maybe the dead in their cemeteries.
I pity the cemeteries though. The little flags on the veterans' graves shivering on their wee stalks. The headstones themselves, and the thin old ones especially, blading into those winds that seem bent on completely scouring off the names and dates their engravings seek to memorialize.
I pity the waters in ponds and rivers that got frozen – zap! – all at once, as they rippled; that were just stopped like people in some sci-fi movie, turned to stone in mid-gesture.
I pity the birds, hopping stiffly about on their sipping-straw legs, finding who knows what to peck from soil that rings like iron under the foot. I pity the squirrel I saw last week, hanging limply from the talons of a hawk that swooped down just eight feet from me to carry him off for supper. My heart pounded at the sight. I thought for a split-second it was one of our cats he carried off.
But no, not the cats.Because the cats are smarter than all of us.
They stay inside on days like the ones we've had lately, lounging around in their pj's, and sleeping late and waking to lick their paws with all the delicacy of ballerinas smoothing the sides of their satin slippers.
As a matter of fact, the cats gave me the only smile I remember enjoying throughout all of this winter cold.
It was one night when my mate and I were curled in sleep, the only human beings in the house.
Under our pile of quilts and blankets we made a single mound, which the cats, in an uncharacteristic move, decided to scale.
I woke with an unaccustomed sense of pins-and-needles on account of their weight. And I started to shoo them off – until it came to me what we must have looked like: Two little pats of butter on a big warm stack of hotcakes.
That image in mind, I turned over again, thought "Embrace it, girl!" then hugged my pillow tighter and went back to sleep.


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WHO: James Olmos
BROWSER Address: https://3DWebWorldz.com
HYPERGRID Address: grid.opensim.life:8002:Inspiration Island
WHEN: Friday 02/08/19, 6:00 PM Pacific Time.
DRESS: Casual. Come as you are, but cover your bits!
Live music and a movie to get you in a weekend mood
About James Olmos
It doesn't matter if he is serving original ballads or catchy covers; James's soothing guitar, harmonious voice, and lyrical prowess will take you on a musical dream not to be missed! Covering songs from Eric Clapton to Norah Jones; Gun's N Roses to John Mayer as well as ORIGINALS that will leave you BREATHLESS!!
Hypergrid Information – Audio Stream Only
(grid.opensim.life:8002:Inspiration Island):
We have you covered no matter how you choose to participate. We understand that video may not be everyone's cup of tea. Virtual Worlders can hypergrid to Inspiration Island at the address above. Join us at The Warehouse for the audio stream only.
3DWebWorldz Information – Live VideoCam
If you want to enjoy the live streaming video, you have to join us on https://3DWebWorldz.com (all you need is an internet browser!) https://3dwebworldz.com (LogIn as Guest or User and teleport to The Warehouse)
Our weekend schedule
This is the first of two shows on 3DWebWorldz this weekend. Why not join us for both?
James Olmos: Friday, 02/08/19, at 6 PM Pacific
Sonya Jevette: Saturday, 02/09/19, 4pm Pacific
Make Inspiration Island your destination every Friday night! Every week, there is a LIVE SHOW or ENTERTAINMENT at 6:00 pm with an AFTER PARTY of some sort beginning at 7:00 PM. Sick around tonight for a mystery movie.


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UCF has had a remarkably bad 0-10 season. This is quite the shocker for the team that entered the season ranked #1 in the only college football poll that matters. Longtime coach George O'Leary retired midseason and it's been grim down in Orlando. But at least Tre'Quan Smith is still providing us with highlights, like this catch here way over the back of a Tulsa defender.
UCF went on to lose the game 45-30.


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Yale University, USA: Using patient-specific neurons
Using patient-specific, iPSC-derived neurons to model neurodegeneration in multiple sclerosis
Principal Investigator: David Pitt, M.D.
Institution: Yale University School of Medicine
Country: USA
Amount Awarded: €75,000
Disease progression varies greatly among people with MS. The reason for this is unknown, but may be related to genetic differences in the susceptibility of nerve cells to injury. Glutamate is a compound that is normally found in the brain that can cause injury to neurons when it is present in excessive amounts. This team proposes to use neuron stem cells that have been derived from skin cells from individuals with MS to test if there are genetic differences in their neurons' sensitivity to injury from glutamate. Several medications have been developed that modulate glutamate, and these could be potential new therapies for people with MS if it can be determined who may have glutamate sensitivity.
What does this mean for people living with progressive MS?
If some people are genetically predisposed to sensitivity to glutamate, this subset of individuals may benefit from therapies that address excessive glutamate to slow or stop disease progression.
Principal Investigator David Pitt
David Pitt, MD, earned his medical degree from the University of Marburg, Germany in 1998. Subsequently, he received postdoctoral research training at the Albert Einstein College of Medicine, NY, where he later completed a neurology residency and served as a chief resident. Dr. Pitt went on to complete a three-year fellowship in Multiple Sclerosis and Neuroimmunology at Washington University in St. Louis. At Yale, he conducts basic and translational research focusing on neurodegenerative aspects of multiple sclerosis. Dr. Pitt is funded by the National Multiple Sclerosis Society (USA) and the NIH and collaborates with several companies on various research projects.
Sign up to our e-newsletterfor updates from our growing global initiative to end progressive MS
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Hovevn Health share articles about :Thuốc Dyrenium , side effects – dosage , Thuốc Dyrenium what disease treatment.Other noted issues. Please refer to the details below.
Generic Name: triamterene (try AM teh reen)
Brand Name:Dyrenium
Medically reviewed by Holevn.org on Jul 30, 2019 – Written by Cerner Multum
What is Dyrenium?
Dyrenium is a potassium-sparing diuretic (water pill) that prevents your body from absorbing too much salt and keeps your potassium levels from getting too low.
Dyrenium is used to treat fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney condition called nephrotic syndrome.
Dyrenium is also used to treat edema caused by using steroid medicine or having too much aldosterone in your body. Aldosterone is a hormone produced by the adrenal glands to help regulate the salt and water balance in your body.
Dyrenium may also be used for purposes not listed in this medication guide.
Important Information
You should not use Dyrenium if you have severe kidney or liver disease, urination problems, or high levels of potassium in your blood. You should not take Dyrenium if you also take potassium supplements, or other diuretics such as or spironolactone.
Call your doctor right away if you have signs of hyperkalemia (high potassium), such as nausea, slow or unusual heart rate, weakness, or loss of movement. You may be more likely to have high potassium if you have kidney disease, diabetes, a severe illness, or if you an older adult.
Before taking this medicine
You should not use Dyrenium if you are allergic to it, or if you have:
severe kidney disease, or if you are unable to urinate;
severe liver disease;
high potassium levels (hyperkalemia); or
if you take potassium supplements, or another potassium-sparing diuretic such as amiloride (Midamor) or spironolactone (Aldactone).
To make sure Dyrenium is safe for you, tell your doctor if you have:
heart disease;
kidney disease;
liver disease;
gout; or
a history of kidney stones.
Using Dyrenium may increase your risk of developing hyperkalemia (high levels of potassium in your blood). You may be more likely to have high potassium if you have kidney disease, diabetes, a severe illness, or if you an older adult.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether triamterene passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
Dyrenium is not approved for use by anyone younger than 18 years old.
How should I take Dyrenium?
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use Dyrenium in larger or smaller amounts or for longer than recommended.
Dyrenium is usually taken once or twice per day. Follow your doctor's dosing instructions.
Take this medicine after eating a meal.
Taking a diuretic can make you urinate more often, which could disrupt your sleep if this happens at night. If you take Dyrenium only once per day, take it in the morning to reduce the chance of night-time urination.
While using Dyrenium, you may need frequent blood tests. Your kidney function may also need to be checked.
Your heart function may need to be checked using an electrocardiograph or ECG (sometimes called an EKG).
This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using Dyrenium.
If you need surgery, tell the surgeon ahead of time that you are using Dyrenium.
Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call 115.
Overdose symptoms may include increased nausea, slow or unusual heart rate, muscle weakness, or loss of movement.
What should I avoid while taking Dyrenium?
Dyrenium may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Drinking alcohol with this medicine can cause side effects.
Do not use salt substitutes or low-sodium milk products that contain potassium. These products could cause your potassium levels to get too high while you are taking Dyrenium.
Dyrenium side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor right away if you have signs of hyperkalemia (high potassium), such as nausea, slow or unusual heart rate, weakness, or loss of movement.
Stop using Dyrenium and call your doctor at once if you have:
pale skin, easy bruising or bleeding;
slow, fast, or uneven heartbeat;
jaundice (yellowing of the skin or eyes);
little or no urination;
signs of a kidney stone–sudden pain in your back or side, vomiting, fever, chills, painful urination, and urine that looks, red, pink, brown, or cloudy; or
low potassium–leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.
Common side effects may include:
nausea, diarrhea;
dizziness, headache;
dry mouth; or
feeling weak or tired.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Dyrenium?
Tell your doctor about all your current medicines and any you start or stop using, especially:
any other diuretic;
heart or blood pressure medicine; or
NSAIDs (nonsteroidal anti-inflammatory drugs)–aspirin, (Advil, Motrin), (Aleve), celecoxib, diclofenac, , meloxicam, and others.
This list is not complete. Other drugs may interact with triamterene, including prescription and over-the-counter medicines, vitamins, and . Not all possible interactions are listed in this medication guide.
Further information
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Copyright 1996-2018 Cerner Multum, Inc. Version: 7.01.
The content of Holevn is solely for the purpose of providing information about Thuốc Dyrenium and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor's prescription.
Reference from: https://www.drugs.com/mtm/dyrenium.html
Cập nhật mới nhất ngày


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Festivals and Events
17 Projects Set for Animation Production Day in Germany
Seventeen projects from eight countries have been selected for the Animation Production Day, a business platform event for the animation industry hosted by the 18th Stuttgart International Festival of Animated Film and FMX 2011.
The two-day event is scheduled for May 3-4 and will bring together 100 representatives of the German and international animation industries
The projects will presented in one-to-one meetings. Representatives of 46 participating companies will meet producers, world sales companies, broadcasters, banks and equity investors to discuss new financing channels, product strategies and possible options for exploitation, as well as the brand potential of their projects.
Seven projects from Germany are among those selected, as well as projects from Great Britain, Spain, Columbia, Lithuania, Russia, Israel and Switzerland. This year, the projects under negotiation can boast a total production volume of more than 65 million euros.
On its fifth anniversary the event will, for the first time, feature a conference which bring together representatives of ARD, ZDF and KI.KA TV channels with German producers for an exchange of ideas and a discussion of current programming challenges. The Conference on TV and Production in Germany for Children, Youth and Animation, will take place May 2 in Stuttgart's Literaturhaus, and is a joint event run by the APD and the German Producers' Alliance. At the conference, the Alliance will present its current study on "TV and production for children, youth and animation". This study will deliver, for the first time in years, authoritative figures on the situation on the German market.


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In The Supreme Court
The State, Petitioner,
Naim Jihad, Respondent.
Gerald C. Smoak, Sr., Circuit Court Judge
Opinion No. 25360
Heard March 21, 2001 - Filed September 17, 2001
Attorney General Charles M. Condon, Chief Deputy Attorney General John W. McIntosh, Assistant Deputy Attorney General Robert E. Bogan, Senior Assistant Attorney General Norman Mark Rapoport, all of Columbia; and Solicitor George M. Ducworth, of Anderson, for petitioner.
Kenneth W. Sheppard, of Peachtree City, Georgia; and Nancy Jo Thomason, of Anderson, for respondent.
JUSTICE MOORE: We granted a writ of certiorari in this case (1) and now address the sole issue whether driving a vehicle with a non-functioning brake light supports a traffic stop. We find it does and reverse.
Fifteen pounds of marijuana were seized from respondent's car after a highway patrolman pulled him over for a broken brake light. Respondent was charged with trafficking in marijuana. At a pre-trial suppression hearing, the trial judge ruled the initial traffic stop was not supported by probable cause because South Carolina law requires only one brake light to be working. Accordingly, the trial judge found the initial traffic stop invalid and suppressed the evidence.
The State appealed the trial judge's ruling. (2) In a 2-1 decision, the Court of Appeals held only one working brake light is required under our statutory scheme and, since respondent had one working brake light, he was not in violation of any traffic law at the time he was stopped. The majority therefore ruled the initial stop was not supported by probable cause and affirmed the suppression of the evidence as fruit of the poisonous tree. See Wong Sun v. United States, 371 U.S. 471 (1963). (3)
Brake lights, or "stop lamps" as they are referred to in Title 56, are governed specifically by S.C. Code Ann. §§ 56-5-4730 and -4560 (1991). Section 56-5-4730 provides in pertinent part:
Any motor vehicle may be equipped, and when required under this chapter shall be equipped, with the following signal lamps and devices:
(1) A stop lamp on the rear which shall emit a red or yellow light and which shall be actuated upon application of the service (foot) brake and which may but need not be incorporated with a tail lamp;
(2) A lamp or lamps or mechanical signal device capable of clearly indicating any intention to turn either to the right or to the left and which shall be visible both from the front and rear.
A stop lamp shall be plainly visible and understandable from a distance of one hundred feet to the rear both during normal sunlight and at nighttime and a signal lamp or lamps indicating intention to turn shall be visible and understandable during daytime and nighttime from a distance of one hundred feet both to the front and rear. When a vehicle is equipped with a stop lamp or other signal lamps, such lamp or lamps shall at all times be maintained in good working condition. No stop lamp or signal lamp shall project a glaring or dazzling light.
(emphasis added). Further, § 56-5-4560 makes it unlawful to drive a vehicle on the highways "unless it is equipped with a stop lamp meeting the requirements of § 56-5-4730." (4)
The trial judge and the Court of Appeals majority read these sections to require only one functioning brake light. The State argues that even though only one brake light is required, when there is more than one brake light on a vehicle, they must both be in good working condition. The State relies on the language in § 56-5-4730: When a vehicle is equipped with a stop lamp or other signal lamps, such lamp or lamps shall at all times be maintained in good working condition.
We agree with the State's reading of these statutes. In addition to requiring a single brake light, § 56-5-4730 also applies to discretionary equipment as indicated in the first sentence: "Any motor vehicle may be equipped, and when required under this chapter shall be equipped. . . ." A motor vehicle may therefore have, in addition to the required brake light, more than one brake light.
Further, § 56-5-4730 clearly evinces legislative intent that even a discretionary brake light must be in good working condition by prefacing the good-working-condition requirement with the conditional phrase "when a vehicle is equipped with a stop lamp. . . ." The word "when" in context here means "in the event that" or "whenever." (5) "When a vehicle is equipped with a stop lamp" therefore means "whenever" or "in the event that" a vehicle is equipped with a stop lamp. This phrase has meaning only if it refers to discretionary stop lamps since reference to the mandatory single stop lamp would not require this conditional phrase. See In re: Decker, 322 S.C. 215, 471 S.E.2d 462 (1995) (a statute should be construed so that no word, clause, provision, or part is rendered superfluous).
The Court of Appeals's interpretation of § 56-5-4730 requiring that only a single stop lamp be in good working condition overlooks the "when a vehicle is equipped" phrase which refers back to the first sentence of the statute providing for both mandatory and discretionary stop lamps. We hold, under a plain reading of § 56-5-4730, it is unlawful to drive with a non-functioning brake light. Accordingly, the traffic stop in this case was valid. The Court of Appeals's decision is
TOAL, C.J., WALLER, BURNETT and PLEICONES, JJ., concur.
1. State v. Jihad, 339 S.C. 325, 528 S.E.2d 696 (Ct. App. 2000).
2. The State asserted on appeal that the suppression of the marijuana significantly impaired its prosecution of the case and therefore the trial judge's ruling was appealable. State v. McKnight, 287 S.C. 167, 337 S.E.2d 208 (1985).
3. On appeal to this Court, the State adopts the position of the dissenter in the Court of Appeals and argues there need only be a reasonable suspicion rather than probable cause to support a valid traffic stop. See Illinois v. Wardlow, 528 U.S. 119 (2000) (reasonable suspicion is a less demanding standard than probable cause). "Reasonable suspicion" does not refer to an officer's speculation there may be some law prohibiting the observed conduct but goes to the sufficiency of his observation. It is uncontested in this case that respondent was actually driving with a non-functioning brake light which satisfies the higher standard of probable cause if such conduct is in fact a traffic violation. Accordingly, we need not address whether a reasonable suspicion is sufficient to support a traffic stop in this case.
4. In addition to these two sections specifically regulating stop lamps, S.C. Code Ann. § 56-5-4410 (1991) provides generally that it is unlawful to drive a vehicle that "is not at all times equipped with lights, brakes, steering and other equipment in proper condition and adjustment as required in this article."
5. Random House Dictionary of the English Language, Second Edition, Unabridged (1987).


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Fossorial water vole (Arvicola terrestris) population cycles and their phase-associated microbial communities
Monitoring of montane water vole populations on the Jura plateau during the phases of a demographic cycle: relative densities, reproduction parameters, weight, relative age (crystalline weight), and microbial community composition. Those data have been collected in the framework of Petra Villette's ...
Mass screening for Alveolar echinococcosis in south Gansu, China
Data related to human population screening and dog surveys carried out in 1996-97, 2005-6 and in 2014/15 in South Gansu, China
Water vole and plant diversity in a productive hay meadow of the Doubs department
Data of 32 vegetation plots located in a productive hay meadow disturbed by water voles. It includes the plant species lists and the associated community descriptors.
Sampling of Mediterranean fan mussel specimens (Pinna nobilis) for molecular analyses of the byssus and of the shell matrix
This document describes a field mission carried out in May 2017, at the Observatoire Océanologique de Villefranche-sur-Mer. This mission aimed at collecting live specimens as well as dead shells from the Mediterranean fan mussel, Pinna nobilis, an endemic species protected by European Directive ...
DAT-Af-BASE: database for azole resistant Aspergillus fumigatus
The University hospital of Besançon has an extensive collection of A. fumigatus isolated from clinical and environmental samples. Azole resistant strains are part of this collection and have been characterized: evaluation of resistance phenotypes, sequencing of the main gene involved in resistance, ...
Cholera database of Democratic Republic of Congo
This database contains information on the weekly monitoring of cholera in the health zones of the DRC since 2000.
DNA Library - CNR Echinococcoses
DNA Library is a database associated to a web interface, created to improve the storage and the life of a biological sample collection, closely related to the research activities of the National Reference Center for Echinococcosis (CNR Echinococcoses, University Hospital of Besançon, France). A ...
EWET : EmsB Website for Echinococcus Typing
The EWET database (EWET-DB) contains genotyping data on the parasite Echinococcus multilocularis, obtained after the analysis of the microsatellite EmsB. A set of information is also avaible on the sampled parasite isolates (host, geographical position, sampling conditions, laboratory of reference, ...
Bromadiolone kinetics in common and montane water vole populations
Field measurements describing the kinetics of bromadiolone in two vole populations (Microtus arvalis and Arviola scherman) after a field control of water voles, Arvicola scherman. Those data have been obtained during Mickael Sage's doctorate.
Grassland vegetation monitoring in the French Jura Mountains
Plot-based vegetation survey. Diachronic observations of the grassland plant communities in the Franche-Comté region.
Permanent grasslands of the French Jura Mountains (synchronic study BioGEcoP)
Vegetation, orthopteran communities, soil and landuse descriptors of 48 mesic grasslands in the French Jura Mountains.
Bromadiolone en Franche-Comté
Anticoagulant rodenticides (bromadiolone) treatments in Franche-Comté
Noise map Besançon 2008
Urban noise (road traffic, train traffic, pedestrian area, springs)
Wildlife Ecotoxicology - Small mammals - Metaleurop Nord
This database presents morphometric (body size and mass, organ mass or size...) and ecotoxicological (concentrations of pollutants in some organs, various biomarkers) data from small mammals (voles, mice, shrews...) captured in the surroundings of a former lead and zinc smelter named Metaleurop Nord ...


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BEIRUT (AP) — Syria will supply "game-changing" weapons to Hezbollah, the chief of the Lebanese militant group said Thursday, less than a week after Israeli airstrikes on Damascus targeted alleged shipments of advanced Iranian missiles bound for Hezbollah.
Israel has signaled it will respond with airstrikes to any future weapons shipments, meaning it could quickly get drawn into Syria's civil war if the Hezbollah chief's declaration is more than an empty threat
Tension has been rising in the region since Israel struck targets inside Syria on Friday and Sunday. Hezbollah and Israel fought several battles in the past three decades, including a 34-day war in 2006 that left some 1,200 Lebanese and 160 Israelis dead.
Israel has largely tried to stay out of Syria's 26-month-old conflict. It never acknowledged the airstrikes, but Israeli officials have signaled Israel's air force would strike against any shipments of strategic missiles that might be bound for Hezbollah.
Israel and Hezbollah have been exchanging threats over the past months.
Israeli officials say the Lebanese militant group has tens of thousands of rockets, though most of them are unguided. The shipments targeted last week included precision-guided missiles, the officials said.
Hezbollah chief Sheik Hassan Nasrallah has said in the past that his group has missiles that can strike anywhere in Israel, including as far south as the Red Sea resort of Eilat.
Meanwhile, Hezbollah and Iran have become increasingly involved in Syria's civil war, supplying troops and military advisers to help Syrian President Bashar Assad fight armed rebels trying to oust him.
Nasrallah spoke Thursday to mark the 25th anniversary of the founding of Hezbollah's radio station, Al-Nour, in a speech televised in Beirut. Nasrallah has rarely appeared in public since the 2006 war, for fear of being targeted by Israel.
Nasrallah said Hezbollah could expect strategic weapons from Syria in the future.
"Syria will give the resistance special weapons it never had before," Nasrallah said. "We mean game-changing."
Nasrallah said the weapons shipments were Syria's response to the Israeli airstrikes. "This is the Syrian strategic reaction," Nasrallah said. "This is more important than firing a rocket or carrying out an airstrike" against Israel.
The military alliance between Syria and Hezbollah will continue, the Hezbollah chief said.
"We in the Lebanese resistance declare that we stand by the Syrian popular resistance and give our material and moral support, and cooperate and coordinate in order to liberate the Syrian Golan," he said.
Israel captured the Golan Heights from Syria in the 1967 Mideast war and later annexed the strategic plateau.
Asked to comment on Nasrallah's declaration, Israeli Foreign Ministry spokesman Yigal Palmor said: "We don't respond to words. We respond to action."
In a related development, Israeli security officials said Thursday they have asked Russia to cancel the imminent sale of an advanced air defense system to Syria.
The officials said Israel shared information with the United States in hopes of persuading Russia to halt the planned deal to provide S-300 anti-aircraft missiles. The Israeli officials spoke on condition of anonymity because they were not authorized to brief reporters.
In Rome, Secretary of State John Kerry said Thursday the transfer of advanced missile defense systems from Russia to Syria would be a "destabilizing" factor for Israel's security.
Kerry said the U.S. has expressed concerns about what such defensive systems in Syria would mean for Israel's security, though he declined to address what the missiles might mean for Syria's civil war.
Earlier Thursday, the Assad regime said it welcomed efforts by the United States and Russia to try to bring the sides to the negotiating table before the end of the month.
Syrian Information Minister Omran al-Zoubi said the government is willing to consider any proposals for a political solution of the conflict, while it retains the right to fight "terrorists," the regime's term for the opposition fighters and their supporters.
Al-Zoubi did not specifically mention the U.S.-Russian initiative in his brief remarks to reporters in Damascus, carried by the state-run SANA news agency.
The main Western-backed opposition group, the Syrian National Coalition, said Wednesday it welcomes the U.S.-Russia effort to reach a political solution but that any transition must begin with the departure of Assad and officials in his regime.
The U.S.-Russian initiative is identical to a plan, set out in Geneva last year, to bring the Damascus regime and opposition representatives together for talks on an interim government. Each side would be allowed to veto candidates it finds unacceptable.
The Geneva proposal also called for an open-ended cease-fire and the formation of a transitional government to run the country until new elections can be held.
Even modest international efforts to halt the fighting have failed as neither side in the Syrian civil war has embraced dialogue, underlining their resolve to prevail on the battlefield.
In Cairo, the U.S. ambassador to Egypt, Anne Patterson, briefed Arab League chief Nabil Elaraby on the U.S.-Russian efforts, according to a diplomat at the Arab League. Patterson called for Arab support for the plan, including pressing the Syrian opposition to back it, said the diplomat, who spoke on condition of anonymity because he was not authorized to discuss details of a private meeting.
Separately, Egyptian Foreign Minister Mohammed Amr Kamel welcomed an international Syria conference and said Egypt is willing to help make it work.
At the United Nations, an Arab-backed resolution calling for a political transition in Syria and strongly condemning Assad's regime's escalating use of heavy weapons and "gross violations" of human rights was circulated Thursday to the 193-member U.N. General Assembly.
The Arab group decided to seek approval of a wide-ranging resolution on Syria in the assembly, where there are no vetoes, to reflect international dismay at the growing death toll, which has surpassed 70,000, and the failure to end the more than 2-year-old conflict.
A General Assembly resolution would also counter the paralysis of the deeply divided U.N. Security Council, where Syrian allies Russia and China have vetoed three Western-backed resolutions aimed at pressuring Assad to end the violence. Unlike Security Council resolutions, which are legally binding, General Assembly resolutions cannot be enforced. But if they are approved, especially by a large majority, they do reflect world opinion and can carry moral weight.
In fighting Thursday, Assad's forces attacked rebel positions in Aleppo and Idlib in the north, said the Britain-based Syrian Observatory for Human Rights. The group said warplanes hit rebels near the Mannagh military air base outside Aleppo.
The rebels stormed the base near the border with Turkey and captured parts of it on Sunday but were later forced to retreat in the face of the regime's superior air power.
In neighboring Idlib province, heavy clashes were under way Thursday outside several army bases near the government-controlled provincial capital, according to the Observatory, which relies on a network of informants inside Syria.
In Damascus, the state-run SANA news agency said government troops regained control of one more village and some land near the border with Lebanon on Thursday. The agency claimed troops inflicted heavy losses on the rebels in Aleppo and Idlib.
In Lebanon, a senior security official said several rockets landed Thursday on Lebanese territory, the latest incident of the Syria conflict spilling over the country's volatile borders. The official spoke on condition of anonymity in line with state regulations. There were no reports of casualties in the northwestern Lebanese town of Harmel.
Associated Press writers Suzan Fraser in Ankara, Turkey, Aron Heller in Jerusalem, Bradley Klapper in Rome and Sarah El Deeb in Cairo contributed to this report.


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We started our journey lighting village Sirohi in Haryana, with solar power in 2012, after which it found its place on the virtual map (read: google maps).
As we spent more time in villages in and around Sirohi, we discovered weaving techniques and intriguing plastic material used in their charpais; and unearthed an underground supply chain of rag pickers that were converting industrial waste plastic wrappers into ropes used for indigenous purposes. Check out our model to know more.
Dedicated to the village that gave us our name, identity and inspiration, we present to you SIROHI.


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Finally Holi arrived.
Giving in to popular demand (masterminded by Anya), ASR (yes ASR!) agreed to have a small pool (more like a big shallow tub) put up at the bottom of the lawns where the children could play Holi to their heart's content. But in return, ASR bargained for diplomatic immunity – he would not play and neither would he be forced to play.
Anya argued with him for over an hour but then she conceded the deal. The stakes were too high.
All the kids had a blast. Anya insisted that the adults too (minus ASR of course) take a dunking in the 'tub' and woe betide if they protested too much, instantly all the kids would be swarming all over them like bees and pummel him or her till then gave in. Khushi and Garima were excused on doctor's orders.
Nani was the most sporting, followed by Mamiji. Even Anjali and Payal had to step into the tub. Khsitij, surprisingly, put up a big fuss and the children cheered loud and long when they finally managed to force him. The twinkle in his eye gave him away, it was clear to the discerning that he had put up an act that so that the children could have some additional fun, at his expense.
This year Devansh had no qualms about joining in all the fun, largely because where his Big Bro and Di went, he simply had to follow suit. And it was the same with Palash. And of course the water was an irresistible attraction and Devansh got his long unfulfilled desire to explore a pool. It took Poo over an hour to clean him up and make him recognizable as ASR's son.
ASR tucked his hands in his pockets and watched the entire messy hullabaloo with a superior smirk alongside a morose Khushi.
Khushi stood watching with a wistful expression on her face, "Aapne jaan bhoojkar hume pareshan karne ke liye itna badiya intezaam kiya na? Aapko pata tha na ki hum iss saal hum paani main nahi jayenge?" she took out her frustration on him.
Arnav's eyes crinkled but he said blandly enough, "Yeah I guess you are right! Tumhe pareshan karne main bahut mazaa aata hai," he put his arm around her and gently steered her away from the crowd. He hiccuped. Khushi stared at him in astonishment.
Was that 'bhang' that he had been drinking?
"Aap ne bhang piya?" Khushi burst out.
He shrugged, "Haan toh?!"
"Par aap toh bhang nahi peete!" she was taken aback.
He shrugged, "Can't get through all this nautanki without a bit of exogenous 'support'," he leaned forward and whispered into her ear, "Waise bhi shaadi ke baad main bahut kuch karta hoon jo pehle nahi karta tha," he waited till his warm intense gaze had its desired effect, she blushed rosily, "Mera 'turnover' jo gaya hai!" he wrapped his arms around her.
Khushi hastily looked around and pushed him ineffectually; she gave up and laughed, she said admiringly, "Aapki yaadasht toh badi achchi hai!" then a bit surprised, "Aapko kaise pata Mamiji ne yeh kaha?"
"Woh… I dunno," he shrugged, his brow cleared, "I think Aakash ne kabhi bataya tha…"
"Aur hume Jiji ne!" Khushi laughed again.
Arnav looked at her glowing face and brushed aside her bangs, "Khushi, I love you Khushi, you know that don't you?"
Khushi smiled at him mistily and nodded her head, "Haan, I too love you, par aap aise kyon bol rahein hain?" she was surprised.
He looked at her regretfully, "I am so busy in my work, I hardly have any time to spend with you, tumhe bura lagta hoga na?" he shook his head, the bhang making him maudlin and sentimental, "Nani ko bhi jabardasti Delhi main rok liya; she must also be unhappy here," his shoulders drooped.
"Arnav," she cupped his face and turned him towards her, "Kya hua? Aap kya baat kar rahein hain hume kuch samajh nahi aa raha hai," she frowned at him, "Yeh sab bhang ka asar hai!" she declared.
He shook his head and turned to leave, she held him back by his hand, reluctantly he turned back to face her, "Khushi," he murmured softly, "Uhh…I was wondering, everything ok between you and Nani? I mean you get along fine right?" he hastily corrected himself at her dumbfounded expression.
"Me and Nani! Kyon? Aisa kyon pooch rahe hai?" Khushi was justifiably amazed at the out of the blue query, then worried, "Nani ne kuch kaha kya?"
"Nahi nahi," Arnav quickly dismissed her concern, aware that he had botched up, he had been a bit worried and concerned about the relationship between the two of them ever since his conversation with Aakash. And a bit guilty too, in his preoccupation with his work, his love, his child, he had as usual not really bothered about what was going on in the house. He really had no clue as to what kind of relationship Khushi and Nani shared, neither had bothered to give him any feedback and he too hadn't bothered to keep track. But Aakash's outpourings left him mildly shaken as his questions had struck a chord, it was a well known fact that two women in the same house was bound to lead to unpleasant ego clashes, but then he consoled himself, maybe he was making a mountain out of molehill, neither had complained and best you keep your nose out of such matters, let them sort it out, he told himself. But then when had he ever listened to reason, 'still I should know, it is my responsibility, after all I forced Nani to stay here and suppose she is not happy?' he worried. Nahi, Khushi would never, he had been sure but still, a niggling doubt demanded clarification and the bhang loosened his tongue, hence the outpourings of guilt.
"Phir?" Khushi questioned him round eyed.
"Nahi," he shrugged, "Aakash said something and I just wondered…" he trailed off unwilling to go into the details. But then he didn't need to, it was suddenly all clear to Khushi, she nodded her head and was suddenly serious, "Oh! Jijaji bhi pareshan hain?" she knotted her fingers, "Jiji is also very unhappy," she looked at him and put her hand on his shoulder, "Hume kuch karna chahiye Arnav."
Arnav looked at her astounded, "What do mean Khushi! Hum isme kya kar sakte hain," he protested, "Husband-wife ka problem hai, personal hai, we can't just interfere like that!"
"Husband-wife! Personal!" Khushi glared at him, "Aap aisa kaise keh sakte hai, aapke bhai hain, aur humari Jiji!"
Arnav looked helplessly at Khushi, "Haan par," he raised his hands defensively, "Ok ok, we will think about it later, maybe talk to Nani about it," he knew he was making a big mistake (Khushi would surely hold him to his promise), but anything to postpone the discussion so not suited for his current state of bhang induced nasha. The mighty khadoos ASR was grappling with a strong wave of nostalgia, his Khushi was still his Khushi, his heart swelled with joy and gratefulness and as the unfamiliar emotions flooded him he felt as if he were on top of the world.
Khushi instantly brightened and nodded her head happily, "Theek hai," she hugged him, "Aur aap humare aur Nani ke baare main chinta mat kariye, Di aur Nani dono humare 'best friends' hain!" she smiled at him brilliantly.
Arnav hurriedly clutched at the slipping edges of ASR's cloak. He looked down at her a bit put off, "Achcha! Woh tumhare best friend hain! Aur main kya hoon?"
A/N Hello friends! A big thank you for participating in the discussion and here's another question – Which do you think is the best way to help Payash? Feel free to drop in with your own unique ideas in the CB as well. And don't worry about putting any ideas in my head, for remember this is a flashback and it has all been said and done! Cheers!
- Arshi could arrange for Payash to get away for a honeymoon to reconnect
- Khushi could try a reverse drama on Aakash, tell him Payal was terminally ill or something
- Nani could recommend that Payash separate out from Mama/mami?
- None of the above (hope to see the naysayers in the CB!)
Click here for Chapter 223


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The first installment of Aqaara has been posted on Outer Places: https://www.outerplaces.com/science-fiction/item/19034-aqaara-two-don-gibson
Please read, share and comment!
The first installment of Aqaara has been posted on Outer Places: https://www.outerplaces.com/science-fiction/item/19034-aqaara-two-don-gibson
Please read, share and comment!
She wanted to leave the party for the tour of the Mali pavilion so that we could steal their catalogs. I was terrified because I had just seen a documentary about how they kept criminals confined with their heads strapped together. But she was insistent, leaning forward, tightening her pants.Traffic was bad, both getting there and then with all of the magazines falling over from their stacks, and there was a roadblock at the bottom of the hill.I cursed her for getting me into this, and I almost turned off into the bushes. She laughed at me. "They don't care about us." And she was right.
The crowd was larger, people up both walkways, chants and holograms everywhere. A bright orange drone floated above, slowly coming down.
"Hello, how are you doing?" It was the man from the Hive, now dressed and atop a glider, floating behind the drone.
"Want me to smash that thing?"
"We're making a film," he replied.
Dee frowned.
"Name's Norich." He raised his eyebrows at her as he glided down. "How would you feel about me filming you now?"
"For what?"
"A document."
"For your personal pleasure?"
"Sort of Cinema Verite." The camera-drone, an orange sloped contraption, floated down over his shoulder. "I'm examining the nature of The Hive for the Ark News. The impetus of that, right? I'm thinking individually, right? Why do we do the things we do?" He looked half drunk, the way he glanced back and forth between them. "Like, what is to experience it?"
Dee shrugged. "Go ahead and try it."
He landed, leaning forward, wincing at the effort to think of an answer that could not be deflected. "Wisdom, knowledge, that is very human."
Dee studied his long face, almost earnest, knowing he wanted to listen, his hands open in front of him, waiting for something. "Sex, that's what I think you're after, sex and more of it." Norich nodded back at her. "You know how people say that men want to have sex with young women to avoid their fear of death? That gorgeous taut flesh, so primal and real, the dream of the boy through the old man, it's got nothing to do with dying, my friend. It's just being alive, that sexual drive, mindless and direct. But to avoid death? No, it's not that. Everything is to avoid death. Eating, drinking, going to the bathroom—"
"What about good driving habits then?" Dee added.
"That's sure as hell part of it, awareness of what you are – your limitations, that you have a perspective, that you're aware that we tend to think that we know something—"
"You men?"
"Us people. That we know something that no one else can exactly understand. Even with as much as anyone might know, in their mind for a certainty, whatever is gathered through books and media, experience, relationships, there's only that, only that perspective."
"Humility then," Dee ventured.
"Yes, that's part of it."
"I think what you really mean is sex," Dee concluded. "And the answer is no."
"It's more our limitations." Norich tried to pat her on the shoulder. "It's all about being aware of that."
"So we're in agreement then." Dee went past him into The Hive.
Alexander Weinstein's moral is as clear as white light in his collection of short stories, Children of the New World, that technology is no replacement for the real world. The stories suffer from what Weinstein terms in Cartographers as "nothing but white light", broad strokes, many of those poorly thought, and no effective detail.
Sentences such as "Can't beat a cold beer," I said, taking a swig (13), '(I) traveled endless hours, numbed by bad sleep and bland airplane food (67), surrounded by pressurized air and bland airplane food (80), 'I stopped talking, hating the clunkiness of words (190) are the clunky norm. Worse is his adolescent portrayal of sex, the male character – let's call him Misogy – obsessed with sleeping with porn stars (38), being fucked so good (112) and fully exposing the vulva (136), leaving the reader to wonder if technology might actually be better than having to read this.
Davis stood in the back corner of the convenience store, nervously eyeing the owner. She was old, an Asian woman, who probably didn't care. Or maybe she did. Maybe she would lecture him and call his step-mother.
Heart pounding, he snapped the Penthouse from the rack and approached. The woman took the magazine, slid it into a paper bag and waited to be paid. He walked outside, pausing at the corner of the parking lot to slide the magazine into his pant leg.
"Hey." His step-brother, Flynn, appeared behind him. "Can I see that after you're done?"
Davis redid his shoelace. "Huh?"
"That Penthouse."
Davis couldn't understand how he had appeared, where he had come from. "Yeah, okay."
It was a good issue, four pictorials, lipstick lesbians, the centerfold Pet leaning back with a cigarette in her hand. He took the magazine to Flynn and went back to his room, laying uneasily on his bed. He never spoke with Flynn. They had nothing to say to each other. And now this. Was this some kind of turning point? Would they talk about the naked women? Which was best? What they liked? What they did as they looked at them? What were they supposed to say? There was a knock. Davis sat up abruptly, crossing the room and opening the door to find the magazine, face down on the beige carpet, Flynn's door closing down the hall.
In the continuing quest for inspiration in writing my science fiction book Aqaara, I was recommended the graphic novel series Saga by Brian Vaughn and Fiona Staples. I was most interested in its apparently profound treatment of sexual themes and imagery, and yet was disappointed to realize that it is neither thought-provoking nor titillating. The work is nothing more than a morass of simplistic morality propped upon a landscape of superficial sexuality in which – surprise! – a transgender character recently appears. The story-line is vapid, the dialogue interminable to say nothing of the farcical content. But worse of all are the references to the authors' own process themselves, their love of books and killing off their babies. Which they never did and really should have.
What one must aim for in the struggle to control the desires was the condition of "ethical virility" according to the model of "social virility". In the use of male pleasures, one had to be virile with regard to oneself, just as one was masculine in one's social role. In the full meaning of the world, moderation was a man's virtue. To be immoderate was to be in a state of nonresistance with regard to the force of pleasures, and in a position of weakness and submission. In this sense, the man of pleasures and desires, the man of non-mastery (akrasia) or self-indulgence (akolasia) was a man who could be called feminine.*
*Taken with a grain or two of salt.
It's a simple thing. Give them what they want. Sweet or sultry. Just open the case.
Anne Imhof's "Faust", German's 2017 entry at the Venice Bienalle, offers little on the surface, except the surface.
It's more about the people watching than the performers – all the legs passing by.And the arms and hands. And then it is high above on a glass platform.
And that's just weird.
Part of the discovery made at Pompeii, the city entombed by ash in 79 AD, a collection of over a hundred objects was found. Many causing offense to common morality of the time, the Cabinet of Lewd Objects – then called more gracefully Cabinet of Reserved Objects – was walled in 1852 so that its memory would be dissipated. In 1860, Giuseppe Garibaldi proclaimed himself Dictator and re-opened the collection for cataloging. In 1931, during the triumph of fascism, the Ministry ordered again its closing, after which, in 1972 it was opened for visitors. The collection is composed of vases, frescoes and mosaics with erotic scenes, little ithyphallic (figures with erections) statues with fauns, midgets, grotesque caricatures, tintinnabula which are wind chimes that have penises with magic powers against misfortune and evil eye. (English translation of Eros in Pompeii: The Town of Venus)
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Powershop, Powerwalls and power plays. The new year has started with a depressingly familiar political tone, but technology and projects march on regardless.
Powershop boss Ed McManus joins the Energy Insiders podcast to discuss his company's ground-breaking deal last week that will result in the construction of Victoria's biggest solar, and two other wind farms. He also explains why his is buying three hydro plants.
The other big news came on Sunday when Tesla announced with the South Australia government that it plans to install rooftop solar and Tesla Powerpacks's at 50,000 homes, creating a "virtual power plant" of 250MW and 650MWh of storage.
McManus explains why this is a good idea, and will benefit consumers, and how the so-called Tesla big battery is already delivering savings for his company through reduced costs.
And McManus tells us how and why the National Energy Guarantee might just work. Of course, it's all in the detail, and whether it favours the big gentailers or not.
To listen to past episodes of Energy Insiders as well as our sister podcast Solar Insiders, please click here.


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Search results for author:"Swee Noi Smith"
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Learning through Computer?Mediated Communication: A Comparison of Australian and Chinese Heritage Students
Peter J. Smith; Jo Coldwell; Swee Noi Smith; Karen L. Murphy
Innovations in Education and Teaching International Vol. 42, No. 2 (May 2005) pp. 123–134
Twelve Australian and 12 Chinese heritage students from a third-year university computer ethics subject completed a Readiness for Online Learning Questionnaire; and six students from each of these two groups participated in a student-facilitated...


text: T-ZERO PRO line Written on Saturday, 24 October 2020 A new line for Trime is coming... Read more T-ZERO PRO line Written on Thursday, 22 October 2020 Introducing the X-Solar Hybrid Read more The Churchill Way Flyovers Written on Monday, 19 October 2020 Read more Green Apple Award Written on Sunday, 20 September 2020 Trime UK win a Green Apple Award for their X-Solar Hybrid lighting tower Read more Trime create a Monster Written on Friday, 17 July 2020 Press Release - New Product for the Mining Markets Read more A-Plant conference Written on Tuesday, 16 June 2020 Benchmark X-Eco lighting during A-Plant conference in Manchester on Wednesday 4th March... Read more X-TR Written on Wednesday, 10 June 2020 Is it a toilet or is it a lighting tower, or is it both? XTR on it's way to final costumer. Read more X-ECO Written on Sunday, 07 June 2020 X-ECO market leader solution is lighting up new Bum Nuttal Plant road construction site along M27 motorway in the south of England. Read more PRESS RELEASE: Caterpillar partner Written on Monday, 01 June 2020 Lighting tower specialists, The Trime Group, partner with Caterpillar Read more Go Solar, Go X-Pole! Written on Thursday, 21 May 2020 Go Solar, Go X-Pole! Read more PRESS RELEASE Written on Monday, 18 May 2020 Lighting Tower Specialist the Trime Group Expands Read more Airport- and Aircraft Lighting Written on Tuesday, 05 May 2020 Flughafen- und Frachtflugzeug-Beleuchtung Read more TRIME X-City Hybrid Written on Sunday, 03 May 2020 1st Mobile Lighting Tower with assisted electrical movement Read more TOP 1000 Written on Sunday, 22 March 2020 TOP 1000 Best Companies in Italy – We are IN. Read more Why Hybrid? Written on Sunday, 16 February 2020 Hybrid technology is becoming the way forward in many industries. Read more Plug-In or Battery Lighting Towers Written on Sunday, 09 February 2020 How to know which one is right for you Read more Greenline vs Standard Lighting Towers Written on Monday, 03 February 2020 Greenline vs Standard Lighting Towers Read more Kuwait Written on Sunday, 19 January 2020 Al-Bahar National Company deliver X-START 6x150W LED. Read more Event & Film Lighting Written on Sunday, 19 January 2020 Surprising places you can find lighting towers. Read more Trime acquires DOA Written on Sunday, 19 January 2020 From khl - International Rental News Read more Living Green - Having an Eco-Friendly Lifestyle Written on Tuesday, 07 January 2020 This year we have seen even more climate change protests... Read more Boels expand their fleet Written on Thursday, 19 December 2019 With this latest investment, the Boels UK fleet of X-ECO LED sets... Read more A-PLANT Written on Monday, 16 December 2019 A-Plant has added 250 of our lighting towers. Read more ELEKTRO-LEHMANN Written on Thursday, 01 August 2019 TRIME & ELEKTRO-LEHMANN & LEHMANN Notstromaggregate Service GmbH:New solutions for events... Read more X-MINE monster Written on Wednesday, 12 June 2019 TRIME introduces X-Mine Monster Read more X-MESSAGE Written on Thursday, 16 May 2019 X-MESSAGE is the first machine in the world that combine an HYBRID solution together with an HIGH EFFICENCY LED SCREEN. Read more New Lighting Section Written on Wednesday, 13 March 2019 Trime has created a new lighting section and provides to its customers a wide range of floodlights sold separately according to customer needs. Read more X-TS, another step forward in eco-sustainable lighting solutions Written on Wednesday, 06 March 2019 Costumers of diesel engine driven only light towers have been consumed by the amount of time it takes to keep a diesel light tower operational. Read more X-TT ideal for events, but not only... Written on Thursday, 14 February 2019 Trime family becomes ever more numerous Read more X-START lighting solution just landed in Casablanca Written on Monday, 11 February 2019 X-START lighting solution just landed in Casablanca in order to light up a very important construction project!!! Read more Trime awarded at the Green Apple Awards Written on Thursday, 15 November 2018 Trime has been awarded at the Green Apple Awards for the environmental care in its engineering activity. A prestigious award that we are really proud of. Read more Limestone Quarry - LED Mobile Lighting Towers Written on Wednesday, 24 October 2018 Trime tells you how we solved a lighting need for mining activities with our mobile lighting towers. Here is our recent case history. Read more TRIME'S LIGHTING TOWERS AWARDED BY A-PLANT Written on Monday, 03 September 2018 Trime has been awarded by A-Plant with the Excellence in Innovation Award 2018 for X-ECO Battery and X-Solar Hybrid lighting towers. Read more News Greenline Written on Thursday, 26 July 2018 Trime R&D department in the pass couple of months have done an amazing job working daily very hard in order to lunch 5 new model machines in a very short period of time! Read more Murphy Plant goes green with Trime towers Written on Monday, 09 July 2018 Murphy Plant, part of the infrastructure company J. Murphy & Sons, has expanded its rental fleet, with a significant investment in our lighting towers. Read more Deloitte rewards the Italian Best Managed Companies Written on Thursday, 07 June 2018 Trime has been awarded by Deloitte with the Best Managed Companies award. An important recognition that rewards the hard work of our company. Read more Illumin8 Lights lead the way with Trime's LED lights. Written on Wednesday, 16 May 2018 Illumin8 Lights continues its collaboration with Trime UK with the purchase of eighty X-ECO LED lighting towers. The rental company owns now 300 Trime lighting sets. Read more Trime's X-ECO lights up Energy Generator Hire. Written on Thursday, 19 April 2018 Energy Generator Hire Limited has acquired thirty-five X-ECO LED lighting towers. An ecological choice that pays off in terms of consumption and durability. Read more Boels joins the Trime chain gang Written on Monday, 02 April 2018 The rental company Boels has acquired seventy-five X-CHAIN LED lighting towers from Trime. Boels possesses now about 800 Trime units. Read more X-Eco Battery, an eco-friendly and portable light tower Written on Monday, 12 March 2018 Trime S.p.a. presents X-Eco Battery, a portable light tower totally compatible with the environment. Here are its technical features. Read more Construction lighting solutions Written on Tuesday, 06 March 2018 Steve Scattolini of FTG Equipment Solutions talks about the future of the world of construction lighting solutions and its suppliers. An industry that must pass through innovation in order to stay healthy, such as Trime is doing with the LED technology. LED is the future By Steve Scattolini Read more Trime's time is well spent at the Executive Hire Show Written on Saturday, 03 March 2018 Trime UK presented its new X-ECO BATTERY lighting tower for the Executive Hiring Show. A great success in terms of public and requests. Read more TRIME celebrated the Chinese New Year Written on Wednesday, 28 February 2018 Thanks to the collaboration with ARKTIC Trading Service Co. from Hanoi – Vietnam, TRIME celebrated the Chinese New Year. Read more X-CHAIN lighting tower, not just light Written on Tuesday, 20 February 2018 Trime has provided our X-CHAIN lighting tower systems to A.C: ChievoVerona, one of the most important football clubs in Italy. Read more Are you ready for the Revolution? Written on Sunday, 11 February 2018 So proud to announce that at ARA show next week we will officially lunch for the first time the following unique lighting towers. Read more The right light Written on Friday, 02 February 2018 Trime Spa confirms a huge investment in brand new mobile lighting towers. A project to offer a better service to our clients. Read more Visit us at Executive Hire Show Written on Sunday, 28 January 2018 Come and see us at:Executive Hire Show - Coventry UK7th & 8th of February. Read more Upcoming Exhibitions Written on Sunday, 21 January 2018 Visit us at: Read more Andrew Owen Written on Tuesday, 09 January 2018 We have appointed the highly experienced sales expert, Andrew Owen, as our new sales manager. Read more X-SMART on USA Written on Monday, 18 December 2017 As already said, all big changes are simple… Are you ready for the new X-Smart mobile lighting tower on fast tow trailer? Read more X-Chain lighting towers solutions for Skanska Written on Wednesday, 22 November 2017 Trime Spa, the leading manufacturer of sustainable site lighting equipment, has confirmed an order for a fleet of their new X-Chain lighting towers solutions from the Swedish division of the construction giant, Skanska. This is the first order from Skanska for Trime lighting products. Read more Royal Dutch Army Written on Tuesday, 14 November 2017 The Royal Netherlands Army has been raised on 9 January 1814-however, its origins date back to 1572; therefore, the Netherlands has one of the oldest standing armies in the world, dating back to the 16th century. Read more Occupational safety Written on Wednesday, 01 November 2017 Discover X-Chain, our line of lighting towers with a patented emergency brake system Read more Executive appointed to reinforce Trime (UK) Written on Tuesday, 03 October 2017 Trime (UK) Limited, the market leading manufacturer and supplier of advanced engine driven LED lighting towers have announced that Ashleigh Webb has joined their sales and marketing team as marketing executive. Read more Welcome Written on Wednesday, 06 September 2017 We are happy to introduce you our new staff members: Andrea Rognoni and Simone Dalu.Meet the team here! Read more New "spare parts" section Written on Tuesday, 20 June 2017 Now available: new "spare parts" section is online at www.trime.it. Each of our machines is equipped with fast movings spare part catalog in the "easy to read" version. Pics and ordering number will guide you to order always right spare parts for each of our lighting towers. Kindly to have, nice to consult, an easy help for all Trime's worldwide costumers. Read more X-Chain & CRAMO Written on Thursday, 01 June 2017 Finnish based Cramo - one of Europe's leading companies specialized in equipment rental services and rental of modular spaces – purchased 165 of the new X-Chain lighting towers. Read more Visit us at IRE 2017 Written on Wednesday, 19 April 2017 TRIME will attend IRE 2017 - Amsterdam from 2 to 4 May - stand 5603 (look at the plan) Read more Trime' lighting towers expand into Northern Ireland Written on Monday, 27 March 2017 Trime UK reports that business in Northern Ireland has got off to a brisk start following the recent appointment of Dungannon-based Glendun Plant Sales as its lighting towers dealer and distributor for the region. Read more Pope Francesco in Milan Written on Tuesday, 21 March 2017 First batch of lighting towers (67pcs in total) ready to go for the Pope visit in Milan Sunday 25th March 2017Primo lotto di torri faro (67pcs in totale) pronte a partire per la visita di Papa Francesco a Milano Domenica 25 Marzo 2017 Read more Executive Hire Show Written on Friday, 03 March 2017 Thanks to Executive Hire Show, we've been crowned as best exhibitor of the congress! Read more 'Outstanding' entries shortlisted for European Rental Awards Written on Monday, 20 February 2017 TRIME is one of the eighteen rental companies and equipment manufacturers from 12 countries that have been shortlisted for the 2017 European Rental Awards. Our X-Eco Lighting Tower has been nominated as Rental Product of the Year. Read more GAP lights up with Trime X-Eco Written on Wednesday, 15 February 2017 UK-based GAP Hire Solutions has purchased the new X-Eco LED 6 sustainable lighting tower from Trime. Read more Boels invests in lighting masts Written on Monday, 03 October 2016 Rental company Boels has expanded its fleet with new stationary lighting masts and balloon lighting masts from manufacturer Trime. Read more


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1970 reprint of the memoir of travels through the 19th century Muslim world by a Spanish spy. Second volume of two. In great condition.
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1970 reprint of the memoir of travels through the 19th century Muslim world by a Spanish spy. Second volume of two. In great condition.
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Where Science Meets Care
At Gen1, we believe that research should keep pace with the patient. That's why we've simplified the clinical trial process and made conducting research easy. Gen1 brings the clinical trial directly to the physician. That way, doctors can stay in their practice, focus on the patient, and avoid extraneous expenses. By harnessing the power of technology, Gen1 Research brings medicine to market faster. Let's make treatment more accessible, and success stories more common.
For Patients
Get exceptional care and advanced treatment, free of cost. Find a trial that's a perfect match. Help others like you find a cure and lead a better life.
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We're by your side from startup to closeout, providing a fully embedded experience. Streamline your clinical trial without compromising quality or care.
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Access our fast-growing network of over 90 multi-specialty physicians. Recruit and retain individuals that are typically unable to participate in clinical research.
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Helping patients is a group effort. That's why we partner with organizations around the United States who are as dedicated to the power of research as we are.
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The Action Alliance's newly-launched Project for the Empowerment of Survivors ("PES") helps to bridge the justice gap in Virginia by connecting survivors of intimate partner violence with the legal services they need.
Since 1993, the Action Alliance has provided sexual assault and domestic violence survivors with emotional support, safety planning, and other trauma-informed services through its toll-free statewide hotline. Over the years, the hotline (and the demand for hotline services) has grown by leaps and bounds, including by adding a dedicated LGBTQ+ helpline, expanding hotline hours to provide 24/7/365 support, and increasing the number of multilingual advocates who are available to answer calls from survivors.
The PES, the hotline's new legal services division, is a natural outgrowth of these existing services. Survivors often have legal questions in addition to other inquiries. While some callers can access the legal services they need through Legal Aid or other pro bono resources, numerous studies confirm the ever-widening justice gap in Virginia and elsewhere.
The "justice gap" refers to the civil legal needs of low-income Americans, versus the legal resources available to meet those needs.[1] In Virginia alone:
- Over 80% of the civil legal needs of low-income individuals go unmet;
- One in eight Virginians is eligible for free legal services from Legal Aid, but there are not enough Legal Aid attorneys available to meet the need for services;
- There is one Legal Aid lawyer per 7,237 low-income individuals in Virginia; and
- Individuals who have attorneys are twice as likely to have a favorable outcome in court, versus individuals who are unrepresented.[2]
The need for free or low-cost legal services is particularly acute for survivors of intimate partner violence, where "[i]ndirect and lasting economic consequences ripple throughout survivors' lives long after the abuse has stopped, compounding their effects and creating increased vulnerability to future abuse."[3]
The PES seeks to bridge the justice gap for survivors in the following ways:
- By partnering with local sexual assault and domestic violence agencies to identify survivors who need legal services;
- By employing dedicated legal interns and advocates to answer legal questions and provide legal information to survivors;
- By employing on-staff attorneys to provide free legal counsel and advice to survivors;
- By referring survivors to community-based private attorneys who agree to take cases on a reduced fee or pro bono basis;
- By training attorneys and advocates to provide trauma-informed legal services and legal advocacy; and
- By helping survivors from marginalized communities pay for private attorneys through the use of our Legal Fund.
If you are a survivor in need of legal services, please call our Statewide Hotline at (800) 838-8238 and ask to speak with a member of our legal team. We are here to help.
If you are an attorney who is interested in providing pro bono or reduced fee services to domestic violence and sexual assault survivors, please contact Carmen Williams, PES Project Manager, at (804) 377-0335, or email us at firstname.lastname@example.com.
Janice Craft is one of two attorneys with the Project for Empowerment of Survivors at the Virginia Sexual and Domestic Violence Action Alliance. Prior to her work with the Action Alliance, Janice served as the statewide policy director for NARAL Pro-Choice Virginia and clerked for the Chief Judge of the Court of Appeals of Virginia. Janice is a graduate of William and Mary Law School, where she served as Editor-in-Chief of the William & Mary Journal of Women and the Law.
[1] See Legal Services Corporation, America's Partner for Equal Justice, https://www.lsc.gov/media-center/publications/2017-justice-gap-report (last accessed Nov. 17, 2017).
[2] "Access to Justice: Free and Low Cost Legal Resources in Virginia," Virginia State Bar, available at http://www.vsb.org/docs/probono/access-guide.pdf (last accessed Nov. 17, 2017).
[3] Shoener, Sara J. & Sussman, Erika A., "Economic Ripple Effect of IPV: Building Partnerships for Systemic Change," Domestic Violence Report (Aug./Sept. 2013), available at https://csaj.org/document-library/Shoener_and_Sussman_2013_-_Economic_Ripple_Effect_of_IPV.pdf (last accessed Nov. 17, 2017).


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When I think of Boho, L.A immediately springs to mind. The desert wanderer vibes and dusky hues mixed with an effortless style that I automatically want to recreate. Come summer, I love to dig out my favourite boho pieces in a bid to adopt an effortless boho look. Whilst the likes of Isabel Marant and Chloé triumph in the effortless boho chic department, I tend to turn to the high street for more affordable pieces to create my capsule summer wardrobe. With that said, I stumbled across this crepe halter neck dress on a recent visit to Forever 21 and had to do a serious double take. Not only was it a mere £19 (I was convinced that the price was wrong) but it had an uncanny resemblance to a Chloé dress I had seen a while back. After heading straight to the fitting room and trying this dress on (I went for an XS for those of you wondering) it really was love at first try. The crepe material, low back and rope halter neck detailing make this dress so pretty and an absolute steal. Naturally I headed straight to the till no questions asked.
As many of you may have seen from my previous blog post, I recently headed to the beautiful island of Mykonos. If your anything like me, you will know what it's like to have a pre holiday wardrobe panic where you think you have nothing to wear. I know full well I do but for most people a holiday only happens once a year so you want to look your best and wear all the pretty clothes that its been too cold to wear in England. This dress seemed like the perfect piece for wandering the pretty streets of Mykonos town. Paired here with a simple lace up tan sandal and straw beach bag, achieving effortless boho chic couldn't be easier or more comfortable. This undoubtedly has to be one of my favourite summer looks, especially with its throw on and go capability. What are your holiday wardrobe essentials?


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A Pilot Study Assessing Intra-Metastasis Administration of Autologous KLH-pulsed Dendritic Cells With Tumoral Radiation Therapy in Patients With Metastatic Pancreatic Carcinoma
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT00843830
Recruitment Status : Terminated (Study closed early secondary to inability to obtain grant funding to conduct.)
First Posted : February 13, 2009
Results First Posted : November 5, 2014
Last Update Posted : December 8, 2015
- Study Details
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
This study is being done to determine whether it is possible to use an investigational vaccine that consists of dendritic cells in patients with pancreas cancer. Dendritic cells are immune cells that are obtained from your blood that are important in the body's immune response to foreign substances. The vaccine would be injected directly into a tumor that has spread to the liver after a short course of radiation therapy has been given to that tumor. The study will try to determine if this treatment would be safe and effective in treating this cancer.
This is a phase 1 pilot study of this treatment. Phase 1 trials test the best way to give a treatment where little is known about its possible risks or benefits. Phase 2 studies then test the possible benefits of a treatment and may show the specific situations where they are seen. Promising treatments are then tested in Phase 3 trials which compare the new treatment to standard treatment in a larger group of patients. Phase 4 trials are those conducted on a treatment after it has been approved for general use outside of research. A pilot study tests a treatment in a small number of patients to learn if and how the treatment could be tested in a larger group. Pilot studies can be performed at any phase but are commonly performed in the earliest phases of research on a treatment.
|Condition or disease
|Metastatic Pancreatic Carcinoma
|Radiation: tumoral irradiation Biological: Dendritic cell vaccination
|Phase 1
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|4 participants
|Intervention Model:
|Single Group Assignment
|None (Open Label)
|Primary Purpose:
|Study Start Date :
|October 2006
|Actual Primary Completion Date :
|December 2008
|Actual Study Completion Date :
|April 2010
Experimental: Treatment Arm
Participants will receive tumoral irradiation and dendritic cell vaccination.
Radiation: tumoral irradiation
On day 1 of the study treatment, patients will begin tumoral irradiation, which will be given daily for 4 days in 6Gy fractions (days 1 through 4)
Biological: Dendritic cell vaccination
Three intra-tumoral injections of 1 ml cell suspensions of KLH (keyhole limpet hemocyanin)- pulsed DC (dendritic cells) will be delivered percutaneously under ultrasound into a selected hepatic metastasis in the outpatient setting.
- The Percentage of Participants That Patients Complete Radiation Therapy, All Three Vaccinations, and Evaluation for Tumor Response Four Weeks After the Third Vaccination. [ Time Frame: 10 weeks ]The primary objective of this study was to evaluate the safety and feasibility of this combined modality protocol in patients with metastatic pancreatic carcinoma. The treatment will be deemed feasible if 80% or more patients complete radiation therapy, all three vaccinations, and evaluation for tumor response four weeks after the third vaccination.
- Number of Patients That Respond to Treatment [ Time Frame: 10 weeks ]To evaluate the anti-tumor response as determined by RECIST criteria
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years and older (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Pathologic diagnosis of pancreatic carcinoma
- Radiologic evidence of hepatic metastasis with at least one lesion > 2.0 cm that is amenable to ultrasound or CT guided intra-tumoral DC injection
- Age > 18
- Life expectancy > 3 months
- Karnofsky Performance Status > 70%
- Patients must not have received any anti-neoplastic chemotherapy, immunotherapy or radiotherapy for the four weeks preceding entry onto the study (six weeks for nitrosoureas and mitomycin C).
- Adequate baseline hematopoietic function defined as WBC (white blood cell) > 3000/mm3, hemoglobin > 9g/dl, and platelet count > 100,000/mm3.
- Adequate baseline organ function defined as creatinine < 2.0, total bilirubin < 2.0 mg/dl
- Patients taking warfarin are not eligible. Adequate coagulation function defined as PT (prothrombin time) < 15, INR < 1.5 and PTT (partial thromboplastin time) < 35.
- Ability to give informed consent
Exclusion Criteria:
- Previous anti-tumor vaccine therapy
- Prior hepatic irradiation
- Known brain metastases
- History of prior autoimmune diseases (e.g. SLE (systemic lupus erythematosus), rheumatoid arthritis, myasthenia gravis)
- Regular corticosteroid use within the past one year or any corticosteroid use in the four weeks preceding study entry
- Evidence of HIV infection, AIDS, Hepatitis B or Hepatitis C infection
- Active bacterial, fungal or viral infection
- Pregnancy or lactation; women of childbearing potential and men must agree to use effective contraception during the course of this clinical trial
- Uncontrolled or unstable medical conditions including angina, arrhythmias, bleeding, or thromboembolic conditions,
- Any medical or psychiatric illness that might compromise the patients ability to tolerate treatment
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00843830
|United States, Michigan
|Universtiy of Michigan Comprehensive Cancer Center
|Ann Arbor, Michigan, United States, 48109
|Principal Investigator:
|Mark M. Zalupski, M.D.
|Universtiy of Michigan Comprehensive Cancer Center
|Responsible Party:
|University of Michigan Rogel Cancer Center
|ClinicalTrials.gov Identifier:
|Other Study ID Numbers:
|First Posted:
|February 13, 2009 Key Record Dates
|Results First Posted:
|November 5, 2014
|Last Update Posted:
|December 8, 2015
|Last Verified:
|November 2015
Pancreatic Neoplasms
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Digestive System Neoplasms
Neoplasms by Site
Endocrine Gland Neoplasms
Digestive System Diseases
Pancreatic Diseases
Endocrine System Diseases
Immunologic Factors
Physiological Effects of Drugs


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Royal Botanic Gardens, Kew
Creating a TV and cinema advert for the world's largest Victorian glasshouse
The brief: attract a new generation of visitors to Kew Gardens
RBG Kew had embarked on an ambitious £41m plan to refurbish the Temperate House, the world's largest surviving Victorian glasshouse. Kew needed a high-quality TV and cinema advert to inspire a new and younger audience to visit the gardens from May 2018. Cue Echosix!
Step 1: exploring client needs
After winning a highly competitive bidding process, we immersed ourselves in Kew's marketing, digital, horticultural and senior management teams to establish what made Kew such a special place. We then submitted three creative concepts to stakeholders for selection.
Step 2: scriptwriting and approval
Once the concept had been chosen by Kew's team, we fleshed out the script and meticulously planned each shot and angle, ensuring the plants, people and architecture of Temperate House were always centre stage.
Step 3: film production
Our film team brought together a crew of young talent, a cast of Kew volunteers to star in the ad and a camera drone to film while restoration work was ongoing. Edits, original music, voiceover and CGI work to disguise the lack of grass around Temperate House were added in post production.
Step 4: coming to a cinema near you
By the end of the project we had created four versions of the film for different mediums – 8 and 12 seconds for digital, 30 seconds for TV and a 60-second version for cinema. The 35-week campaign delivered 263 million impacts across all mediums, establishing Temperate House as the must-see attraction for the summer.
Our film