text:
The over-arching purpose of this project is the primary prevention of FGM in Kenya. The project adopts the view that FGM is a public health as well as a human rights issue that fits well with the current thinking on primary prevention of violence against women and girls. The project aims to stop FGM before it occurs by identifying and challenging cultural and social norms that encourage violence on women and girls and promoting the alternative norms of safety, equality, and respectful and non-violent relationships.
The project is grounded on the social norms theory, an approach which has been applied widely in the US with significant successes in reducing some forms of violence and risky sexual behaviors. The project will focus on increasing protective factors for vulnerable girls by coordinating a social norms and advocacy campaign. The project will promote positive social and cultural norms that foster protective factors culminating in the creation of a social movement towards ending FGM.
The project will seek to overturn the current scenario where prevalence of risky behavior is usually over estimated while protective factors are normally underestimated. This is expected to result in the breaking of the culture of silence surrounding the practice of FGM and countering the social and cultural narratives that condone and support FGM. The project will increase the amount of information available on positive social norms by making positive appeals rather than focusing on negative consequences and attaching social stigma to the practice of FGM.
The project is set up at three ecological levels; schools, household and community. We have therefore adopted the Socio-Ecological Model (SEM) to reach in-school youth, teachers, parents, and the general public who will constitute our first-line of change-makers. The media will be engaged to raise the profile of FGM and to promote positive social norms among the general public.
There is a growing consensus and evidence base that violence against women is predictable and preventable, and there is growing interest in what works at the primary prevention level. This approach is an emerging area of interest internationally.
The project will be rolled out in Kajiado County in two (2) urban and two (2) rural communities picked based on predetermined (FGM related) indicators that will form the criteria for selection, and serve as the epicentre of the social change. Kajiado County has particularly been selected because of the rural-urban dichotomy, FGM prevalence levels, SOWED Kenya's physical presence, community good-will and good working relationship with national and county government, and the growing network of SOWED Kenya's partners. In addition, SOWED Kenya has the authority of the State Department of Education to work with schools on topical issues in the county valid for the duration of the project. We are also implementing a donor funded project to counter violent extremism in local schools which the project will leverage on. In 2014/15 we (together with LVCT Health) conducted and launched a formative, (qualitative & exploratory) study in Kajiado County on the types, forms and risk factors of child abuse, and the role of teachers and parents in the primary prevention of the same, which culminated in the design of interventions considered by this project.
Project Objectives
- Building Social-movement through recruitment of End FGM ambassadors.
- Strengthening the capacity of peace clubs to integrate End-FGM campaigns and increase protective factors for in-school girls by building safety nets to address End FGM in 4 public schools.


text:
This article will be permanently flagged as inappropriate and made unaccessible to everyone.
Are you certain this article is inappropriate?
Excessive Violence
Sexual Content
Political / Social
Email Address:
Article Id:
Reproduction Date:
Mauritius – United States relations are bilateral relations between Mauritius and the United States.
Official U.S. representation in Mauritius dates from the end of the 18th century. An American consulate was established in 1794 and was closed in 1911. It was reopened in 1967 and elevated to embassy status upon Mauritius' independence in 1968. Since 1970, the mission has been directed by a resident U.S. ambassador. There is a U.S. Embassy in Port Louis, Mauritius.
Relations between the United States [1] and Mauritius are cordial and largely revolve around trade. The United States is Mauritius' third-largest market but ranks 12th in terms of exports to Mauritius. Principal imports from the U.S. include aircraft parts (for Air Mauritius), automatic data processing machines, diamonds, jewelry, radio/TV transmission apparatus, telecommunications equipment, agricultural/construction/industrial machinery and equipment, casino slot machines, outboard motors, books and encyclopedias, and industrial chemicals.
Mauritian exports to the U.S. include apparel, sugar, non-industrial diamonds, jewelry articles, live animals, sunglasses, rum, and cut flowers. Mauritian products that meet the rules of origin are eligible for duty- and quota-free entry in the U.S. market under the African Growth and Opportunity Act. In September 2006, the Governments of Mauritius and the United States signed a Trade and Investment Framework Agreement to remove impediments and further enhance trade and investment relations between the two countries.
More than 200 U.S. companies are represented in Mauritius. About 30 have offices in Mauritius, serving the domestic and/or the regional market, mainly in the information technology (IT), textile, fast food, express courier, and financial services sectors. The largest U.S. subsidiaries are Caltex Oil Mauritius and Esso Mauritius. U.S. brands are sold widely. Several U.S. franchises, notably Kentucky Fried Chicken, Pizza Hut, and McDonald's have been operating for a number of years in Mauritius.
The United States funds a small military assistance program. The embassy also manages special self-help funds for community groups and nongovernmental organizations and a democracy and human rights fund.
Principal U.S. Embassy Officials include:
This article incorporates public domain material from websites or documents of the United States Department of State (Background Notes).[2]
Media related to at Wikimedia Commons
South Africa, Tanzania, Mozambique, Réunion, Madagascar
New York City, United States, American Civil War, Hawaii, Western United States
Samsung Electronics, Fujitsu, Ibm, Sony, Electronics
Mauritius, France, Pakistan, Bangladesh, Politics of Mauritius
Myanmar, United States, Barack Obama, Washington, D.C., Export
United States, World War II, Barack Obama, Democracy, Vietnam War
Cyprus, United States, Foreign relations of the United States, Foreign relations of Cyprus, Washington, D.C.

subset: commoncrawl


text:
Too Faced is just one of those brands that I've always wanted to buy from. Is it the kitsch packaging or the amazing reviews? I just don't know. Unfortunately I haven't quite got the bank balance yet to be spending £25 on a blusher so instead I headed to the high street to find something similar.
I came across Makeup Revolution's I Heart Makeup collection and as you can imagine their Blushing Hearts Blushers caught my eye. I've heard wonders about them and like everyone says, they really are a great dupe for the Too Faced ones for only £4.99!
At first glance they're pretty much identical and the range of shades are decent. The heart shaped packaging is identical to Too Faced's just without the pretty floral print.
Inside there's three shades, all baked, which consist of a bright pink, dusky pink/coral and more peachy/coral shade in the Candy Queen of Hearts shade. The colours are so pretty and I'm loving them for summer – I've even started using it more than my beloved Stila blusher!
The pigmented formula is soft and easy to blend and the fine shimmer doesn't make you look too similar to a mermaid. Subtle enough for a blusher but you could still work it in and use it as a highlighter perhaps if you have a slightly darker skin tone.
This is definitely a winner for me and I no longer feel the urge to try out the Too Faced Blushers. Praise the Lord for Makeup Revolution!
Repurchase? Yes.


text:
Faced with the task of obtaining accreditation, Carroll County Health Department is asking voters to approve a new property tax levy.
CARROLLTON On the verge of having insufficient funding within a year, Carroll County Health Department officials are asking voters for more financial support.
An additional 0.03-of-a-mill property tax issue will be on the Nov. 7 election ballot. If approved, the five-year levy would generate $280,365 a year.
Carroll County officials familiar with situation say the county Health Department's upcoming challenge to comply with new accreditation standards is a big reason for the request.
"The basis behind what is going on is the state is requiring them to do an accreditation to receive some of the grants they receive," Carroll County Commissioner Lewis Mickley said. "If they don't complete that accreditation, they would lose eligibility for some of that grant funding. They are anticipating a very large expense involved."
To get the levy on the election ballot, the county Board of Health needed authorization from the county commissioners. This will be the second time the Board of Health has asked voters to approve a new tax levy.
Carroll County voters rejected a 0.04-of-a-mill request last November by a 7,259 to 5,483 vote.
Board standards
The accreditation standards are coming from the Public Health Accreditation Board, a nonprofit organization with a mission of improving health of people through enhancing the performance of public health departments. The Public Health Accreditation Board launched its national accreditation program for public health departments in 2011.
A year later, the Ohio Legislature established the Legislative Committee on Public Health Futures. That group concluded that the quality of service from some city and county health departments in Ohio was not being delivered at a level residents should expect. Consequently, the state Legislature gave the Ohio Department of Health authority to require all local health departments apply for accreditation by 2018 and become accredited by 2020.
"The mandates the state has placed on us to be accredited includes a lot of additional expenses," said Dr. Walter Stine, president of the Carroll County Board of Health. "One of those is to have an accreditation coordinator. It is a very long and difficult process to get this done. If we don't get this accreditation, then we won't be eligible for a lot of grants is my understanding."
Efforts to contact Carroll County Health Commissioner Leann Cline were not successful. But she wrote a letter to Carroll County commissioners earlier this year indicated her department "is forecasting insufficient funding in fiscal year 2018. The insufficient funding is due to a continuous increase in operating expenses over revenue."
Among some reasons Cline mentions in her letter are a decrease in licensing fees and a fluctuation in state and federal grant funding. She also cites a change in how the Ohio Department of Health disburses grant funding in 2016. The department now has to make upfront payments in anticipation of grants, and submit monthly or quarterly expense accounts for Ohio Department of Health approval.
"Based on their current levels of funding, they wouldn't have the labor hours to get done what they need to get done," Mickley, the county commissioner, said. "They certified to us they were going to have insufficient funds to get done what they need to get done."
Revenue and expenses
Cline presented to county commissioners a table showing revenue and expenses over a six-year period ranging from 2011 to 2016. Her chart also includes the carryover from year to year. In 2016, the chart shows the Carroll County Health Department had revenue of $1.13 million and expenses of $970,883. The carryover for that year was $138,118.
In year 2011, the revenue was at $1.14 million and expense level was slightly more than $1 million.
In Cline's letter to the county commissioners, she mentions a likely increase in expenses for personnel and training. This would be part of the preparation process to obtain accreditation.
Having the property tax levy revenue "would allow us to keep functioning through this accreditation process so we could get accredited, so we can continue to get the state funding," Stine said.
Along with grants, the county Health Department receives payments for services from the townships and villages in Carroll County. These payments from the political subdivisions are known as apportionments.
"They went to the townships before," Carroll County Auditor Lynn Fairclough said. "But so many of the townships in Carroll County are hurting. They do pay a certain percentage. But she (Cline) wanted that increased. I believe they showed her they don't have additional money to give up."
If voters approve the 0.3-of-a-mill levy, it would cost the owner of a home with a $100,000 valuation $10.50 a year. Some of the duties of public health departments include inspecting well sites and septic systems. Another duty is administering vaccinations and monitoring occurrences of infectious diseases or illnesses.
"Some other things we would like the public to know, being a small health department, it is hard to find qualified people to do all of the things that we do; nurses, sanitarians," Stine said. "We have good people, it is hard to retain them. The reason is we don't pay our people the way others do because we don't have the budget."
The Ohio Department of Health, in a written account of what the accreditation process involves, indicated that some public health departments having difficulty getting accreditation could wind consolidating with others.
"I think that is actually what the state is nudging us toward," said Stine. "The local health departments disappear and they are replaced by regional health departments. You lose your local health board, your local health department and your local control of what is going on. That is what I want to avoid."
Reach Malcolm at 330-580-8305
or firstname.lastname@example.com
On Twitter: mhallREP


text:
A preschool program at Utah State University for children on the autism spectrum has received an additional $75,000 in ongoing funding from the Utah Legislature.
According to Tom Higbee, director of the Autism Support Services: Education, Research and Training (ASSERT) program at the Center for Persons with Disabilities, the funds will be used to expand the program.
"It means more kids, more graduate students and more undergrads," he said. "We're excited to be able to expand. It lets us do more of what we already do: the training of students and serving families of children with autism."
ASSERT will be opening an afternoon session starting fall 2014 with room for at least two more families. Openings will be allocated to the morning or afternoon session based on what works best for the school district and the parents.
Sen. Lyle Hillyard was instrumental in securing the additional funding for the program, Higbee said.
"It's very exciting," he said. "We've never gotten increases (in funding), only decreases that were then restored. This is the first-ever addition."
Related links:
- USU ASSERT Program
- USU's Center for Persons with Disabilities
- USU Emma Eccles Jones College of Education and Human Services
Contact: Dr. Thomas Higbee, 435-797-1933, email@example.com
Writer: Sue Reeves, 435-797-1977, 435-797-1977, firstname.lastname@example.com


text:
custom by crash, fork lift operator.... That just hurts.
Search found 109 matches
- Mon Oct 01, 2018 9:25 am
- Forum: General Discussion
- Topic: Starrett #123 26" Vernier Caliper
- Replies: 21
- Views: 9513
- Fri Sep 21, 2018 11:07 am
- Forum: General Discussion
- Topic: oilless compressors
- Replies: 16
- Views: 4979
Re: oilless compressors
I needed an indoor low output oil less. Chose this as no one could stand the noise of equivalent output noise makers. https://www.amazon.com/Makita-AC001-Compact-Air-Compressor/dp/B00SCSBPQA/ref=sr_1_6?ie=UTF8&qid=1537545881&sr=8-6&keywords=makita+air+compressor Three years of intermittent daily use...
- Fri Sep 14, 2018 9:37 am
- Forum: Build Log
- Topic: Father & Sons build project: Fitchburg Northern (2.5" scale, 7.5" gauge)
- Replies: 36
- Views: 31856
Re: Father & Sons build project: Fitchburg Northern (2.5" scale, 7.5" gauge)
That is so great. Makes me feel good to see kids actually working with their hands instead of staring at an electronic device. Carry on.
- Fri Sep 14, 2018 9:33 am
- Forum: General Discussion
- Topic: 60° v block
- Replies: 8
- Views: 2362
Re: 60° v block
Just FYI, in a previous job we/I had a 60 degree 1" mic for a particular 3 flute job. It was a Starrett thimble 0.0001" carbide faced and when worn the cost to resurface the anvils resulted in a new mic. It was a lot more than $100 though. Currently, this $201 is the cheapest on Amazon; https://www....
- Thu Sep 13, 2018 9:03 am
- Forum: General Discussion
- Topic: Interesting article on diamonds
- Replies: 6
- Views: 2311
Re: Interesting article on diamonds
40+ years ago worked in a large job shop plant that made Aluminum Oxide parts. 92%, 96%, 98%, and 99.5% purity compositions. All hard (fired part) grinding was done with diamond wheels, metal bonded mostly, using water based coolant. Green machining was primarily done with carbide single point tools...
- Tue Jul 31, 2018 8:54 am
- Forum: The Junk Drawer
- Topic: Glue for Plastic in Gasoline Tank
- Replies: 31
- Views: 9550
Re: Glue for Plastic in Gasoline Tank
can you heat weld it? Soldering iron?
- Mon Jul 16, 2018 2:53 pm
- Forum: General Discussion
- Topic: How to Steady Small Parts on Workbench?
- Replies: 23
- Views: 7258
Re: How to Steady Small Parts on Workbench?
Prime Day - Panavice 301 on sale https://amazon.com/Panavise-301-PanaVise-Standard/dp/B0002BC1AY/ref=gbps_img_m-8_add6_a45d7110?smid=ATVPDKIKX0DER&pf_rd_p=8ac44747-5904-4589-8814-e212bb08add6&pf_rd_s=merchandised-search-8&pf_rd_t=101&pf_rd_i=13887280011&pf_rd_m=ATVPDKIKX0DER&pf_rd_r=EBHGPNPE7K0QJS7Z...
- Wed Jun 27, 2018 9:13 am
- Forum: Riding Scale Railroading
- Topic: Your RR grading methods??
- Replies: 50
- Views: 37183
Re: Your RR grading methods??
On weed control.... Roundup now has a 365 version claiming to control weeds for a year, pre-emergent built in. I am old so not too worried about contracting cancer from new exposures but wear gloves and use a really coarse spray/solid stream. Blackberries are prevalent in Northern California where I...
- Fri Jun 22, 2018 9:25 am
- Forum: General Discussion
- Topic: Is MSC Totally Useless?
- Replies: 45
- Views: 12465
Re: Is MSC Totally Useless?
Sigh: Don't buy enough there to get the good prices. It's all a matter of what the traffic will bare. If you can sell stuff for 5X and 8X your cost you'll likely be very profitable at the end of the year as long as you don't price your self out of business. For myself in business and personal needs ...
- Wed May 30, 2018 3:12 pm
- Forum: General Discussion
- Topic: Scale weight
- Replies: 10
- Views: 2976
Re: Scale weight
Just to make the discussion a bit more obtuse. Coefficient of friction is "constant" for a given materials pairing. In the case of railroads we are dealing with concentrated loads and things aren't so "constant". A round wheel on a rail starts out a a point load and progresses to a line load which w...
- Wed May 16, 2018 10:29 am
- Forum: General Discussion
- Topic: 3-phase Motor Design (small model)
- Replies: 11
- Views: 3278
Re: 3-phase Motor Design (small model)
When that rotor spins thee will be a lot of centripetal force trying to throw those magnets. Just saying.
- Mon May 14, 2018 8:50 am
- Forum: The Junk Drawer
- Topic: Never enough time
- Replies: 1881
- Views: 231208
Re: Never enough time
Excellent solution, can see myself making a couple of these. May use a similar technique on my jeep can too.


text:
I first met Yukako Ichikawa when she was managing the floor of Matsuri (with near military precision). These days, her former husband's restaurant has closed down, but around the corner her own home-style Japanese venue has a dedicated following. One of her devotees was kind enough to vouch for my commitment to her strict focus on environmental awareness and sustainability. Once inside, I left myself (and my three fellow diners) in her hands, so the dishes you see are sharing creations...
Your "guilty-free" meal will proceed smoothly if you imagine you've stepped into your kindly Japanese grandmother's home.
She'll chide you gently (but emphatically) toward reducing food waste. So expect to find only sustainable amounts of seafood in your inside-out brown rice Salmon Rolls ($9.30/8 pieces), and Sashimi Salad ($20).
Tasty organic Chicken Misozuke ($25.70) arrives grilled with white miso sauce; the Wakame Avocado Salad ($12.15) is compelling; and the crisp onion and scallop Kakiage ($5.90/serve) is also a winner. I tried hard to like the raw Jerusalem Artichoke Sushi Rolls, but couldn't quite get beyond finding them surprising!
Prices are reasonable, and it's thirty percent cheaper if you finish your meal. (Don't consider any shortcuts, Grandmother Yukako's already onto them if her sign in the toilet is anything to go by!)
Her restaurant is licensed, and the certified organic Temple Bruer Chenin Blanc ($30/bottle) suits the cuisine. To dine here on dishes like this Salmon Hotpot, you currently need to be introduced by a member, or stroll past in the hope that her 'Members Only' sign is not on display…
To enjoy this restaurant, it's best if you agree that food wastage is a serious issue. If you don't think so, you'd probably be best to dine somewhere else. It's also good for vegans (menu is clearly marked), vegetarians and organic food fans.
460 Cleveland Street, Surry Hills


text:
Reroute of a Segment of Single Phase 7. 2-Kv Overhead Powerline - Meridian Oil (Ac 1014)
Author(s): Jamie A. Karlson
Year: 1993
This resource is a citation record only, the Center for Digital Antiquity does not have a copy of this document. The information in this record has been migrated into tDAR from the National Archaeological Database Reports Module (NADB-R) and updated. Most NADB-R records consist of a document citation and other metadata but do not have the documents themselves uploaded.
If you have a digital copy of the document and would like to have it curated in tDAR, please contact us at firstname.lastname@example.com.
Cite this Record
Reroute of a Segment of Single Phase 7. 2-Kv Overhead Powerline - Meridian Oil (Ac 1014). Jamie A. Karlson. 1993 ( tDAR id: 315229)
This Resource is Part of the Following Collections
Investigation Types
Reconnaissance / Survey
Geographic Keywords
08067 (Fips Code) • Colorado (State / Territory) • La Plata (County) • North America (Continent) • United States of America (Country)
Spatial Coverage
min long: -108.381; min lat: 36.999 ; max long: -107.481; max lat: 37.64 ;
Individual & Institutional Roles
Prepared By(s): Archaeological Consultants for Bureau of Indian Affairs
Record Identifiers
NADB document id number(s): 616291
NADB citation id number(s): 000000344435
General Note: Sent from: Archaeological Consultants for Bureau of Indian Affairs


text:
|Night Market
|Night Market
The famous Cameron Highlands Night Market "Pasar Malam" is right smack in the center of Brinchang town. It opens during the weekends during normal weeks. But during school holidays or public holiday it opens nightly and they start as early set-up at 3 pm and will end up 10pm or so, you can buy vegetables, flowers, fruits, souvenirs gift, t-shirt, strawberry, tea, etc. It is a lot of food stalls at the pasar malam. Night market also near all the local restaurants with walking distant.
After visiting the fruits and vegetable farms, you might want to buy some. The market is a good place to look for everything under one roof. The main markets are located in Kea Farm and on Saturday nights a night market comes alive in Brinchang offering an abundance of fruits, flowers, vegetables and souvenirs, not to mention food!
白天参观水果和蔬菜农场旅游景点, 周五、周六及学校假期晚上最好的活动,当然是游览Brinchang"碧兰璋"夜市场。这是个一站式购买天堂。这里有大量的本地水果(西红柿、柑、橙、番茄、爱情果、番石榴、水晶梨 等)、花卉、蔬菜 (象胡罗花椰菜、卷心菜、蘑菇、豆、豌豆、花茎甘蓝、芹菜、胡椒、阔叶菜和其它种类的蔬菜) 纪念品和各式各样的食品应有尽有。感受这里夜间的冷,天然冷气空调,如遇到下雨或吹风的季节夜晚特别寒冷。


text:
Flight Arena Sourcein Flight, santoki, Tutorials by santoki
Hello Everyone,
I've decided to release Flight Arena's source as a donationware. There are no restrictions or limitations on this release.
If this release was helpful in anyway, consider donating. The source code has been compiled through Flash CS4. So you will need CS4 of higher (cs4, cs5, or cs5.5).
If you have any questions about the code or implementation feel free to ask me.
Hope this continues on the Cowon s9/J3 app/game community!
Here's the link to the file: [DEV]flighArena
Was this post helpful?Consider donating to help replace Santoki's lost s9.
One Comment
Thanks! This will be a great game!!!


text:
How does the iGaming affiliate business work? Find out what kind of entrepreneurs are profiting from the 400 billion dollar industry of internet gambling.
Posts tagged "business"
Is your personal life safe when writing tips for gambling?
As I feel a bit tired discussing about gambling, investing and making money all the time for the past 10 years, I thought of starting to write about other stuff I like, under my real name this time. After all, I do have hobbies other than finding the lows of a stock price, predicting which… Continue reading


text:
Property Management Newsletter - Nov/Dec 2018
Fresh Faces at PRD Kyogle
We've had a number of changes occurring at our office, with Shania Jeanneret leaving us to join her family in Queensland. Sadly, Lara Kennedy is also wrapping up with us at the end of the year to spend more time with her three young children.
On the plus side, we've found a wonderful and experienced new agent to join our Property Management team—Leigh Fraser has years of experience with real estate in Casino, and we are thrilled to have her join our team! Leigh lives with her partner and three children in Fairy Hill, and is an active member of the Casino Netball Association. Leigh can be contacted on firstname.lastname@example.com
We've also had Graham Cruickshank join us recently as a rural sales agent. Graham has extensive rural experience from WA to QLD before recently settling in Collins Creek with his wife, and he is another wonderful asset to our team. Graham can be contacted on 0499 988 809 or firstname.lastname@example.com
Holidays Are Coming!
Our office will be closed for the Christmas holidays from the 22nd of December and reopening for 2019 on the 2nd of January. For all landlords and creditors who receive End of Month disbursements, we will be doing one disbursement on the 20th of December, and another one when we return on the 2nd of January. Please contact us on 02 6632 3380 if you have any queries or concerns.
· Irwin Street, Kyogle—3 bedroom house with views over town, $330 per week
· Gardner Lane, Kyogle—refreshed 3 bedroom house, $300 per week
· Kyogle Road, Kyogle—low-set 2 bedroom unit, $200 per week
· Summerland Way, Kyogle—central storage shed, $44 per week
· Gardner Lane, Kyogle—2 bedroom home with self-contained 1 bedroom unit downstairs, $359,000
· Irwin Street, Kyogle—two-story 3 bedroom home with town views, $349,000
· Saville Street, Geneva—tidy 3 bedroom home with excellent tenants in place, $295,000


text:
Have you ever thought about dying? Have you imagined how you would like your final days to be? Thinking about your death may not be your first choice of things to do, but it is an important one. Life is fragile, and none of us knows how long we will live. One concrete thing we can do to prepare is decide what type of care we would like at the end of our life, and let others know about it ahead of time. In this article and next month's I would like to consider the importance of end of life decisions.
In a message to participants in the World Medical Association's 2018 European Meeting on End-of-Life Questions, Pope Francis said that when it comes to end-of-life care, treatments should always be based on human dignity with the person's best interests in mind. He stressed that the medical options provided must avoid the temptation either to euthanize a patient or to pursue disproportionate treatments that do not serve the integral good of the person. He pointed to the importance of palliative care, "which is proving most important in our culture, as it opposes what makes death most terrifying and unwelcome – pain and loneliness."
Here at Jennings we have supported people at the end of their lives for seventy-six years. We believe that human life is sacred, but not absolute. Death is an inevitable and natural part of life. As Pope Francis said, we are here to support people in their final days and hours. Our own Jennings Hospice carries out that mission in a most beautiful and caring way. The most helpful way each person can prepare for their journey from this life to the next is to consider the kind of care they would like to receive at that time, and express their wishes formally by completing the Advance Directives, to inform their family, friends, and health care professionals. Next month we will consider the importance of the Advance Directives in setting the stage for the final act of our lives on earth!
Mission and Ministry Matters is written by Sister Valerie Sweeney, SND, Chief Mission Officer at Jennings


text: Call-for-Proposal (CFP) is announced today (Link). This will remain open ffrom Feb. 01 to Feb. 20, 2016. The area chosen for healthcare domain in this round of CFP and topics suggested (Link), came from the workshop held on 21st January, 2016 at ICMR HQ., New Delhi (Link). This was jointly chaired by Dr. Soumya Swaminathan, Secretary, DHR & DG, ICMR and Prof. Partha P. Chakrabarti, Director, IIT Kharagpur. Prof. Indranil Manna, Director, IIT Kanpur & IMPRINT-India National Coordinator made opening remark through video conference. Mr Manoj Jhalani, Joint Secretary, Department of Health & Family Welfare, Dr M Ariz Ahammed, Joint Secretary (PSU), Department of Pharmaceuticals provided the perspective of healthcare domain and their expectation from IMPRINT activities. The discussion continued and distinguished representatives from DeitY, DST, DBT, DRDO, THSTI, ICAR, NBRC, NHSRC, CCDC, PHFI, SBISR, NIMR, ICPO, NIRRH, NIOH, NICED, NIE, CII, Welcome Trust, AIIMS, ICMR, IISc and IITs shared their view and extended support.


text:
As part of a study before people are actually sent to Mars, a team of volunteers spent 520 days locked inside a fake spaceship. To see if they could all stay alive and not, you know, kill each other.
It was mission success, as the six men - three from Russia and one each from China, Italy and France - emerged the other day safe and sound. So how'd they get along and not die of boredom?
According to 32 year-old participant Alexander Smoleyevsky, whenever tensions threatened to boil over between the men, they'd all settle in for a few rounds of Counter-Strike.
Which only shows these were unique men, blessed with the patience required for the epic voyage for Mars. I mean, put me up against a camper and a cheat for 17 months and I won't just get upset, I'll kill them with my bare hands.
UPDATE 1-'Mars crew' played Counter-Strike to cool tempers [Reuters]
You can contact Luke Plunkett, the author of this post, at firstname.lastname@example.com. You can also find him on Twitter, Facebook, and lurking around our #tips page.


text:
|U.N.C.L.E. - David McCallum?
16 magazine. 1957-2001. A 'fan' publication. Written —primarily—for teenage, American girls. The editorial focus was on television and teen male music celebrities.
How did an editor who extolled the talents of David Cassidy and Paul Revere & the Raiders ever gain such influence? Well, for a start, she gave us answers: What does the Dave Clark Five eat for breakfast? How tall, really, is the Monkees' Davy Jones? What about Paul McCartney's favorite color? Are Sonny and Cher dating or married?
Just considering the career of Gloria Stavers (1926-1983) causes one to hold, and balance, sets of opposed virtues, tastes and interpretations. She is evasive, on one page jabbering about Gary Lewis and the Playboys, the next, discussing the career of Lenny Bruce or getting physical with Jim Morrison.
|Gloria glammed
How this former magazine subscription clerk and model helmed bubblegum pop promotion with such élan has as much to do with ambition and self-confidence than discernible talent. It's as if she willed herself into existence.
As editor-in-chief, she never accepted advertising and readership peaked at more than five million in 1964. Actually, her talent was quite discernible.
The magazine offered clean, sober intimacy, unpinned with grade-school photo collages and non-threatening confessions, trivializing real-world, contemporary concerns. There was little chest hair. Gloria knew who paid the bills.
|Gloria editing
She focused on boys but occasionally let girls through the door—Connie Francis, Hayley Mills, Patty Duke, Susan Dey, Marie Osmond, Farrah Fawcett. But young male readers generally went elsewhere to look at pictures of pretty women.
When she died, Dave Marsh in Rolling Stone opined… "[we have] lost America's original pop-music writer, the force behind what was at one time the most influential and widely circulated rock publication in America."
Dave Marsh wrote that?
Gloria Stavers knew, intuitively, that pop culture is interchangeable with
commercial culture: therein lies its genius, its banality, its endurance, and its fragility.
|Jim and G-L-O-R-I-A


text:
Cool quotient, hot button topics
Mumbai's LGBT film festival Kashish gets 'Top Five Coolest LGBT film festivals in the world' accolade, with mix of celebrations, sizzle and celebrity attendance
Tomorrow, Sunday December 1, is a red ribbon day. The red ribbon is a global symbol of awareness about HIV. Perhaps the most robust anti-HIV/AIDS program is going on within gay community. Gay, bisexual and other Men who have Sex with Men (MSM) are one of the most susceptible segments to HIV/AIDS.
Even though the 80s decade saw realization creeping in about HIV/AIDS and the gay community, it was marked first by ostracism, misconceptions and then paranoia. Several LGBT movies and books, are a window to those years and the work that was being done in the field in order to create awareness.
This year's Lesbian Gay Bisexual Transgender (LGBT) film festival called Kashish Mumbai International Queer Film Festival 2013, had screened two important documentaries on HIV called 'Vito' by Jeffrey Schwarz which was a moving documentary about Vito Russo, filmmaker and activist who spoke out vocally about the need for low cost AIDS drugs in the late 80s. Another called, 'United In Anger' by Jim Hubbard was a revealing documentary about the ACT UP movement where men and women across races, classes and sexualities came together to work in fighting the AIDS epidemic in USA in the 1980s.
It was this topicality, diversity and visibility coming together, which may have been a factor in Kashish making it to MovieMaker Magazine's 2013 Top Five Coolest LGBT film festivals in the world. Kashish made its debut in 2010 and is the country's only mainstream LGBT film festival. Sridhar Rangayan, the festival director says that KASHISH which means attraction in the Urdu language, celebrates good cinema, but more importantly highlights hopes, desires, struggles and victories of the LGBT communities around the world. "It is a way of raising the rainbow flag high above proudly." The rainbow is symbolic of the gay community because the different colours stand for diversity.
MovieMaker, has been publishing its annual list of coolest film festivals from around the world every year. This year, it decided to expand that and add niche categories like Documentary and Horror/Sci-Fi Festivals, Short Film and Comedy Festivals and Environmental/Social Cause /Women's Film Festivals, LGBT and Ethnic/National Film Festivals. They asked their readers to nominate and vote for what they see as the 'coolest'.
When asked specifically about how one would define coolest, Rangayan says, "The definition of coolest was seen as a combination of quality cinema, great parties, alternative venues, shoestring-budget, the opportunity to gawk at celebrities and connect with fellow movie makers --- a mix that they might not get to see anywhere else. Over four months, they received more than 15,000 votes and finalized the audiences favourites."
Kashish did have pre-event parties where the community could connect, it was held on a budget, in fact, the organizers were looking for 'crowd funding' for the festival and had a slew of celebrities endorsing it. Whether it was Bollywood's Simone Singh, who was most memorable in 'Being Cyrus' at the opening night or the fact that top awards at the festival were sponsored by Anupam Kher, the glitzy association means that stars who are always so careful about their image, are now unafraid of being seen at, or associated with a queer-centric film festival. When you see that there was sponsorship by a Bollywood name, one realizes that the 'support' they talk about is not just on the surface.
Having said that, there are still some celebrities who are wary of being seen at a mainstream LGBT event. Yet, organizers are confident that this would change in a very short time. Talking about physical spaces, Rangayan says that Kashish has been screened at mainstream places. "In 2010, it was screened at PVR Juhu and in the next three years at Cinemax Versova." From physical spaces to mental ones, the LGBT film festival is one more in a slew of events aimed at bringing greater acceptance of the community. Like brazen placards say at LGBT events in the city these days: 'We're here, we're queer, get used to it'.
Sign up for all the latest news, top galleries and trending videos from Mid-day.comSubscribe


text:
Law Firms
Practice Areas
Marketing Opportunities
Frequently Asked Questions
Publicizing Guidelines
Lawyer Directory
Law Firms
Practice Areas
Labor Law - Management
Labor Law - Management
Labor Law - Management
Labor Law - Management involves the legal representation of employers and their management in all facets of federal, state, and local labor law and in managing their relationships with employees and, where present, labor unions.
Representation of private employers is subject to federal jurisdictions pursuant to the National Labor Relations Act and Railway Labor Act, and includes: advising and handling representation petitions and disputes, decertification and de-authorization elections, unfair labor practice and carrier interference charges and proceedings, union jurisdictional disputes, negotiation of collective bargaining agreements, arbitration of union grievances and contractual disputes, managing and responding to labor strikes, lockouts, picketing and concerted activities, representation in federal and state court injunction proceedings, and managing and responding to union boycotts and corporate campaigns.
Ogletree, Deakins, Nash, Smoak & Stewart
Ogletree, Deakins, Nash, Smoak & Stewart
Find a Ranked Labor Law - Management Firm
Other Practice Areas
See overviews for the practice areas included in our Best Law Firms research.
Select Practice Area
Administrative / Regulatory Law
Admiralty & Maritime Law
Advertising Law
Antitrust Law
Appellate Practice
Aviation Law
Banking and Finance Law
Bankruptcy and Creditor Debtor Rights / Insolvency and Reorganization Law
Bet-the-Company Litigation
Biotechnology Law
Business Organizations (including LLCs and Partnerships)
Civil Rights Law
Closely Held Companies and Family Businesses Law
Commercial Finance Law
Commercial Litigation
Commercial Transactions / UCC Law
Communications Law
Construction Law
Copyright Law
Corporate Compliance Law
Corporate Governance Law
Corporate Law
Criminal Defense: General Practice
Criminal Defense: White-Collar
Derivatives and Futures Law
DUI/DWI Defense
Economic Development Law
Education Law
Elder Law
Eminent Domain and Condemnation Law
Employee Benefits (ERISA) Law
Employment Law - Individuals
Employment Law - Management
Energy Law
Energy Regulatory Law
Entertainment Law - Motion Pictures & Television
Entertainment Law - Music
Environmental Law
Equipment Finance Law
Ethics and Professional Responsibility Law
Family Law
Family Law Mediation
FDA Law
Financial Services Regulation Law
First Amendment Law
Franchise Law
Gaming Law
Government Relations Practice
Health Care Law
Immigration Law
Information Technology Law
Insurance Law
International Arbitration - Commercial
International Arbitration - Governmental
International Mergers & Acquisitions
International Trade and Finance Law
Labor Law - Management
Labor Law - Union
Land Use & Zoning Law
Legal Malpractice Law - Defendants
Legal Malpractice Law - Plaintiffs
Leisure and Hospitality Law
Leveraged Buyouts and Private Equity Law
Litigation - Antitrust
Litigation - Banking & Finance
Litigation - Bankruptcy
Litigation - Construction
Litigation - Environmental
Litigation - ERISA
Litigation - First Amendment
Litigation - Health Care
Litigation - Insurance
Litigation - Intellectual Property
Litigation - Labor & Employment
Litigation - Land Use & Zoning
Litigation - Mergers & Acquisitions
Litigation - Municipal
Litigation - Patent
Litigation - Real Estate
Litigation - Regulatory Enforcement (SEC, Telecom, Energy)
Litigation - Securities
Litigation - Tax
Litigation - Trusts & Estates
Mass Tort Litigation / Class Actions - Defendants
Mass Tort Litigation / Class Actions - Plaintiffs
Media Law
Medical Malpractice Law - Defendants
Medical Malpractice Law - Plaintiffs
Mergers & Acquisitions Law
Mining Law
Mortgage Banking Foreclosure Law
Municipal Law
Mutual Funds Law
Native American Law
Natural Resources Law
Nonprofit / Charities Law
Oil & Gas Law
Patent Law
Personal Injury Litigation - Defendants
Personal Injury Litigation - Plaintiffs
Privacy and Data Security Law
Private Funds / Hedge Funds Law
Product Liability Litigation - Defendants
Product Liability Litigation - Plaintiffs
Professional Malpractice Law - Defendants
Professional Malpractice Law - Plaintiffs
Project Finance Law
Public Finance Law
Railroad Law
Real Estate Law
Securities / Capital Markets Law
Securities Regulation
Securitization and Structured Finance Law
Sports Law
Tax Law
Technology Law
Timber Law
Trademark Law
Transportation Law
Trusts & Estates Law
Utilities Law
Venture Capital Law
Water Law
Workers' Compensation Law - Claimants
Workers' Compensation Law - Employers
See Overview
Featured Firms
Frazer Ryan Goldberg & Arnold LLP
Bonnie L. Booden, Attorney at Law P.C.
Search All Law Firms
Best Law Firms
The annual
U.S. News – Best Lawyers
"Best Law Firms" publication is the definitive rankings guide to 14,000 firms in 127 practice areas in 188 metropolitan regions and 8 states.
Preview the Publication


text:
Welcome to Collaroy Plateau Community Kindergarten – your local Community Based Kindergarten/Preschool.
Collaroy Plateau Community Kindergarten is located in Collaroy Plateau on Sydney's beautiful Northern Beaches. At the time of European settlement the Northern Beaches was the traditional home of the Guringai people. We acknowledge and respect the values and customs of the Guringai people who are the traditional custodians of this land whereupon Collaroy Plateau Community Kindergarten is situated. We pay our respects to the elders both past and present and welcome all Aboriginal and Torres Strait Island people to our Preschool.
At CPCK, we accept the responsibility of developing an awareness and appreciation of Aboriginal history and culture and the diversity of the many cultures found within the Preschool community which, we believe, strengthens and enriches our lives and the lives of our children.
Our Story
CPCK offers a play-based, child-initiated preschool curriculum across three key environments. We provide a social environment that fosters a strong sense of community and belonging, an emotional environment that is beautifully nurturing and a physical environment that is natural and inspiring.
We provide care and learning under the unique community-managed, not-for-profit service delivery model. Community management facilitates child-centered decision making that compliments and reflects the local community. There is a strong sense of connection for families as CPCK nurtures relationships and networks that support children through the transition to school and society.
The sense of community at CPCK is enhanced by its over 60-year history of caring for Northern Beaches preschoolers. Many families continue to open the CPCK doors across multiple generations.
Children attend on the same days each week, interacting with the same classmates and teachers. Our long-established teachers are experienced, passionate, energetic and dedicated. In this social context, children are able to develop a sense of belonging that extends outside of the family unit. Their experiences are meaningful, their independence grows and they develop ownership of their learning.
We provide two-day and three-day programs for children aged 3.5 – 5 years at our location of Hall Avenue, Collaroy Plateau. Application is free and can be made online. We invite families to visit our preschool and experience first-hand the unique learning environment we have created for our children.
Our preschool is on the L80/180 bus route with a bus stop at the front of the preschool. The bus travels from the city along Pittwater Road before heading up to Collaroy Plateau. We are therefore easily accessible for anyone without a car who is travelling from the city, Dee Why, or anywhere on Collaroy Plateau. Street parking is available as well.
Click here for more information on Community Preschools: Preschools – education for life
We would like to thank Northern Beaches Council for their continued support of Collaroy Plateau Community Kindergarten through the provision of the Preschool building premises and property. Northern Beaches Council and Collaroy Plateau Community Kindergarten continue to work in partnership with each other to uphold a long standing community service that continues to provide to the local community since 1954 in the form of preschool Education and Care.
Enrol now –
- Preschool education for your child in the year prior to school
- Long standing, highly experienced and qualified teachers and educators
- Friendly families who will welcome you as part of the Preschool community
- The same children attend the same days in the same class with the same teachers
- Subsidies available for 3 and 4 year old children for families with a Low Income Health Care Card and children from an Aboriginal and Torres Strait Islander background
Phone us to organise a tour – 9982 6167


text:
Brett Kavanaugh. Photo: Alex Wong/Getty Images
Supreme Court nominee Brett Kavanaugh has moved a step closer to his confirmation after he submitted a 110 page questionnaire with another 2,000 pages of material to the Senate Judiciary Committee on Friday, reports Politico.
What they're saying: Senate Judiciary Committee Chairman Chuck Grassley praised Kavanaugh in a statement for completing the document, calling it "the broadest and most comprehensive questionnaire" ever sent by the committee. The questionnaire contained biographical information, previously delivered speeches, writing and past court filings from the prospective judge.


text:
Customer Testimonials
We're very proud of our excellent reputation. Below are a selection of comments and testimonials from our customers.
"May I express my thanks for the excellent work carried out by your team on my premises. Everything seemed to go like clockwork and nothing was too much trouble. A very satisfactory job."
Jane Delaney, Chester
"rom my first polite and courteous meet with you, through all the work carried out with constant care and efficiency by your hard working team to the completion of the work, with which I am very pleased. I would recommend your company without hesitation."
Mrs Watson – Ellesmere Port
"Very pleased with the work carried out, a few problems arose which were rectified and carried out very professionally. Excellent approach with no payment until job finished and customer satisfied with work carried out. Returned after a few weeks to make sure everything was still OK. Also the men doing the work were all very pleasant and efficient, tidy workers."
Adam Rogers, Sandbach
"I am writing this letter to say how happy we are with the workmanship of the drive you laid for us recently. We had an old cracked, sloping tarmac surface with inadequate drainage, which required a complete overhaul. This included digging up the old surface, ensuring good drainage, and then laying tarmac with paving edges. The result is exactly as we requested, and we are delighted with the end result."


text:
|TRASH Gordon
TRASH Gordon is a science fiction adventure book which OSCAR THE GROUCH reads to his pet WORM SLIMEY to help him sleep. Introduced in SESAME STREET Season 35, the segments appear at the end of every episode, & replace the older sponsor tags.
"TRASH Gordon" features Gordon as a parody of "Flash Gordon", who finds himself stranded on strange planets & comes up with non-combative ways of overcoming his adversaries. Each segment ends with Gordon reminding viewers of the letter & number of the day.
Starting with Season 38, TRASH Gordon is only seen occasionally. Other times, OSCAR reads SLIMEY a different story, which also ends with Gordon announcing the episode's sponsors. In 2 episodes, The Adventures of Gina the Veterinarian replaced TRASH. The segment was retired in Season 39.
In the 2007 book Abby Cadabby's Rhyme Time, OSCAR is reading TRASH Gordon: Space Glory.
TRASH Gordon's AdventuresEdit
Several of the beginning & ending sequences are reused in several episodes; thus the chapters feature random numbers that are duplicated & progress out of order.
Season 36 (2004)Edit
| Planet MUD
|TRASH is attacked by the Muddy Mudons, until he gives them some apple pie a la Mud.
| Planet WORMHole-5
|TRASH combats of a gang of WORMS by reading them to sleep from a book of his own adventures.
| Planet Gorgonzola
|Poor Trash's nasal passages are threatened by the Stinky Cheese Guys, whom he clears with a sneeze.
| Planet of ROTTEN Bananas
|TRASH saves himself by taking out an Intergalactic Space Monkey, which makes the "bananas split".
| Planet Pizza
|TRASH is chased by a smelly pepperoni & anchovy pizza (w/ extra garlic), till he boxes & sends it off to New Jersey.
| Planet Honk
|TRASH is cornered by a gang of noisy Honkers. He solves the problem by hosting a Honker-DUCKIE-Dinger Jamboree.
| Planet Penguin
|TRASH feeds a big smelly fish to a gang of hungry penguins.
| Planet Dinger
|TRASH is almost driven off a cliff by Ding the Merciless, until he whips out his hotel bell, & they both have a ding-a-long.
| Giant Space Chicken
|TRASH drives his spaceship around a giant space chicken, for no other reason than to get to the other side.
| Planet Very Hairy
|TRASH brushes & combs the hair of the planet's residents.
| Planet Chicken
|TRASH handles a mob of angry chickens by playing "Clucky Clucky Chicken" on a tape player.
| Planet Oink
|TRASH is bothered by a gang of oinking pigs, until he puts on his earmuffs.
| Planet Snore-a-Lot
|TRASH can't get to sleep cause of the snoring Snorecians. He solves the problem by playing his bugle & waking them up.
| Planet DIRTY Laundry
|The smelly dirty laundry runs away when confronted with TRASH's box of laundry detergent.
| Planet Stuck-in-the-Muck
|TRASH frees a duck from being stuck on a mucky rock - but then becomes stuck himself.
| Planet SCRAM
|TRASH is confronted by a gang of GROUCHES shouting "SCRAM!" until he pulls the old snake-in-the-can trick on them.
| Giant Grumpy Guppy
|TRASH scares away a giant grumpy guppy by pretending to be a kitty cat.
| Planet Huff-&-Puff
|TRASH handles the wind of a The Big Bad Wolf by fighting air with air.
| Giant Cranky Monster Baby
|TRASH handles the baby by giving it a giant bottle.
Season 36 (2005)Edit
| Planet Itch-on-Your-Back
|TRASH & the Itchies have an itch on their backs which they can' reach. They all cooperate by scratching each other's backs.
| Planet TRASHpile
|TRASH is cornered by giant piles of TRASH, which he scares away with a TRASH CAN.
| Planet Triangle
|TRASH finds himself taunted by the planet's residents until playing his triangle.
| Planet of the Shoes
|TRASH plays music to get a pair of wingtips to dance away.
| Planet Nothing
|TRASH breaks a cycle of inactivity by reading a book of his own adventures.
| Space Bunnies
|Surrounded by Space Bunnies (all played by Benny Rabbit), TRASH throws a head of cabbage, thereby dispersing the crowd.
| Planet Pots & Pans
|TRASH bangs the biggest pot tops together, persuading the Pots & Pansians to stop doing the same. Video: Elmo & Zoe's Scientific Exploration
| Planet Spaghetti
|TRASH distracts a pasta dish with a pair of meatballs.
| Planet of the Cakes
|On the Crummy Planet of the Cakes, TRASH blows out a birthday cake's candle.
| Planet Double-Trouble
|TRASH Gordon comes face to face with his double.
| Planet Surprise
|TRASH looks for a surprise, but gives up. Suddenly, a gang of Surprisians pop up & surprise him with a party!
Season 37 (2006)Edit
| Planet Spaghetti
|TRASH fends off a meatball with a sneeze.
| Planet of the
Giant Ringing Telephone
|TRASH conquers the phone by answering it.
| Planet of the Stinky Sock
|TRASH copes, with its lone resident by taking off his own sock, forming a pair.
| Planet Upside-Down
|TRASH turns himself upside down to avoid scaring the Upside-Downians.
| Planet Screechy Violins
|TRASH conducts the GROUCHES' playing with a baton.
| Furballs
| TRASH encounters a flock of furballs, which he finds are actually friendly.
Video: BIG BIRD's Wish
| Planet Fairytale
|TRASH contacts Little Bo Peep by interstellar cell phone to bring her sheep home.
| Planet Vacation
|TRASH is heroically tired & relaxes on a lawn chair.
| Planet Conga Line
|TRASH is unable to stop dancing...until he changes the Conga Liners' radio station.
| Planet Booboo
|TRASH bandages the Booboobians' booboos.
| Planet Pebble In Your Shoe
|TRASH shakes the pebble out of his shoe, inspiring the Pebble People to do the same.
More picsEdit
See alsoEdit
- GROUCH books
- TRASH Gordon (character)
- TRASH Gordon (disambiguation)
- "TRASH Gordon" on the Muppet Wiki
- "TRASH Gordon" on the OSCAR THE GROUCH Wiki
|Previous page:
|Next page:
|TRASH CAN (disambiguation)
|TRASH Gordon (character)


text:
Local and general anesthetic agents are commonly used in pregnancy, especially for epidural or combined spinal epidural analgesia at delivery. Although surgery requiring general anesthesia is less common, such use is still relatively frequent.
Local anesthetics are given by injection or topically, and include benzocaine, bupivacaine (Marcaine, Sensorcaine), chloroprocaine (Nesacaine), camphor, dibucaine (Nupercainal), levobupivacaine (Chirocaine), lidocaine (Xylocaine, Octocaine), mepivacaine (Carbocaine, Polocaine), pramoxine, prilocaine (Citanest), procaine (Novocaine), ropivacaine (Naropin), and tetracaine (Pontocaine). For neuraxial analgesia, low doses of bupivacaine, lidocaine, or ropivacaine – with or without a small dose of an opioid such as fentanyl – are commonly used. Use of injectable anesthetics for dental procedures also is common in pregnancy. Maternal toxicity involving the central nervous and cardiovascular systems may result from inadvertent intravenous administration or excessive doses.
Topical anesthetics are commonly used in dermatologic products; many are over-the-counter (OTC) products with multiple trade names not listed here. Such agents include benzocaine, butamben, cocaine, dibucaine, lidocaine, pramoxine, prilocaine, tetracaine, and dyclonine (a bactericidal and fungicidal local anesthetic used in lozenges and throat sprays for sore throats). The three topical cocaine products are controlled substances. Because of rapid absorption that can produce toxicity in the user, they are best avoided in pregnancy. Ethyl chloride (chloroethane) is a refrigerant used as a topical anesthetic. Although there are no reports of its use in pregnancy, the low absorption suggests that it is safe.
Benzocaine and pramoxine are available in OTC preparations for anorectal indications, such as hemorrhoids. The human pregnancy data are limited, but because there are more than 50 such products and hemorrhoids are common in pregnancy, these agents appear to be widely used in pregnancy. Systemic absorption may occur from mucous membranes or from damaged skin with the amount absorbed dependent on the dose.
The local anesthetics available for ophthalmic use are lidocaine (Akten), proparacaine (Alcaine, Ophthetic, Paracaine), proparacaine combined with fluorescein (Flucaine, Fluoracaine, Flurate, Fluress, Flurox), and tetracaine (Altacaine, Tetcaine).
In the above situations, with the exception of cocaine, the risk of any aspect of developmental toxicity from appropriate doses and administration of local anesthetics appears to be rare or nonexistent.
General anesthetics can be classified as injectable, gases, or volatile liquids. The injectable agents include droperidol (Inapsine), etomidate (Amidate), fospropofol (Lusedra), ketamine (Ketalar), methohexital (Brevital), midazolam (Versed), propofol (Diprivan), and sodium thiopental (Pentothal). The volatile liquids include desflurane (Suprane), enflurane (Ethrane), halothane (Fluothane), isoflurane (Forane), methoxyflurane (Penthrane), and sevoflurane (Ultane). All of the agents in these two categories of general anesthetics have the potential to cause neonatal depression or adverse neurobehavioral effects if used close to birth. For most agents, developmental toxicity during other periods of gestation, including organogenesis, has not been reported, but the human pregnancy experience is either absent or very limited. Moreover, the animal reproduction data, when these agents were used alone, were reassuring.
Because nitrous oxide is a gas, concerns have been raised about the potential for adverse effects on the embryo-fetus, as well as the potential effects on women of reproductive potential working in surgical areas. Moreover, when used for surgery, nitrous oxide is always combined with other general anesthetic agents. In animals, the gas is an embryo-fetal toxin (growth restriction, structural anomalies, and death), but the maternal exposures were sometimes high and prolonged. Long-lasting effects reported in animals include permanent brain damage resulting in abnormal behavior effects in motor development and general activity.
In humans, reports have described spontaneous abortions, infertility, and decreased birth weight in exposed pregnancies and in women of reproductive potential working in surgical areas and dental offices. Many of these retrospective reports were subject to self-reporting and/or recall bias, as well as confounders such as lack of information on exposure dose, type of anesthesia, use of other drugs, maternal age, and smoking. Scavenging and ventilating surgical rooms will lessen the exposure of personnel, but will not completely free the area of waste gases. Fortunately, the data do not support an association between acute or chronic nitrous oxide exposure and structural anomalies, but the news for neurotoxicity is troubling.
A 2004 study compared 40 children (ages 5–13 years) born to female physicians and nurses who were exposed to waste anesthetic gases (specific agents not identified) with 40 nonexposed controls matched for age, gender, and maternal occupation. The developmental milestones in the two groups were similar, but the exposed children had significantly lower gross motor ability and more evidence of inattention/hyperactivity. Moreover, the level of exposure was significantly and negatively correlated with fine motor ability and IQ performance (Birth Defects Res. A. Clin. Mol. Teratol. 2004;70:476–82). This study supported the hypothesis that occupational exposure to waste anesthetic gases during pregnancy might be a risk factor for minor neurological deficits in the offspring. Although more data are needed, women of reproductive potential working in surgical areas should consider decreasing or eliminating their exposure to anesthetic gases if pregnancy is a possibility. Moreover, postponing elective surgery until after pregnancy or, at least, after the period of organogenesis, also should be considered. Pregnancy tests should be conducted in any woman of reproductive potential before surgery.


text:
I normally work in many UNIX-like environments using Xterm. I have grown fond of the non-blinking block-cursor it uses. In fact, I have grown so accustomed to it (especially in Vi) that it has become difficult to edit without it. Now that I am working with Windows XP... well, you get the idea.
Does anyone know any program, command, registry entry, ANSI escape sequence, or technique to get the aforementioned cursor in the standard Windows XP command-prompt (cmd.exe)? Using alternatives (such as Console) is not possible in the environment I am working in.
Any help is greatly appreciated.


text:
Royal Mail Postal Rate Change 2020
The date for the 2020/21 postage tariff updates for Royal Mail and Parcelforce Worldwide has been confirmed as Monday 23rd March 2020, with the latest franking rates and savings on standard stamp prices listed below. Simply download the sheets to see Mailmark savings up to 34% against stamps, click on the 'Machine Instructions & Checker' for machine update information, or fill in your details below to be kept updated on postage rates.
Franking Machine Downloads
To make sure your machine is ready for the new Royal Mail rates, please click below for download instructions, or to check that the new rates are uploaded to Mailmark devices.
Call our dedicated Rate Change team if you have any questions:
0800 652 9178 – For Mailmark and franking machines that update online
0800 652 6246 – For older machines that update with rate cards/chips
What Happens If You Use The Old Rates?
Although modern Franking technology is designed to make sure you pay the best rate for your mail, your machine does have to be updated with the latest Royal Mail products, service and rates to ensure you make the most of the franking savings and avoid any surcharges for underpaid mail.
Under the Business Customer Surcharge guidelines, any underpayment on franked mail can produce a charge for the missing postage, along with an administration fee per item. Your franked mail will still be delivered without delay, though via your unique Die number Royal Mail will write to the business re the reason for any charges, or simply collect the underpayment (and reduced fee) directly on newer Mailmark machines. Royal Mail FAQs on Surcharges
As the new tariffs will differ by a few pence from the current rates, any franked mail using the old rate could incur a charge, so it's important that your machine is updated for the changeover on 23rd March 2020. We'll update the download links when available and inform TMR customers via email, though please register interest above, or call customer services if you have any questions.
Request a call back
We'll call you back, leave us your details below and we will call you back.


text:
City Hall Hours
Mon-Fri 7:30 - 4:00
City of Mannford
300 Coonrod Road
Mannford, Oklahoma 74044
Phone (918) 865-4314
Fax (918) 865-5270
Welcome to Mannford, Oklahoma!
Located off of the Cimarron Turnpike just 20 miles from downtown Tulsa, Mannford provides small town living with the conveniences of a major metropolitan just minutes away. Perhaps the most valuable asset to residents and visitors of Mannford is the beautiful Lake Keystone. A 26,000 acre lake with a reputation for world class fishing, Lake Keystone is a magnificent destination for swimming, boating, skiing, camping, hiking and RVing.
Mannford provides its residents amenities not typically afforded to communities of their size. The Mannford Activity Center provides organized exercise and sporting activities as well as an indoor pool. Mannford offers good schools, a safe community, year round recreation and friendly neighbors. Come find out why we say Mannford is a great place to live, work and play!
Phone Payments 866-277-1216
Pay Online


text:
Skip to Content
Rush Copley Medical Center
Home > Services We Offer > Hospitalists
Many Rush Copley Medical Group primary care physicians have partnered with Rush Copley Hospitalists to manage the care of their patients while they are hospitalized at Rush Copley Medical Center. By using a hospitalist, a primary care physician has more time to dedicate to their patient's office visits.
A hospitalist is a physician who specializes in the care of patients who are admitted to the hospital. They have undergone special training and are experienced in managing complex medical issues. They work solely at the hospital and are available to take care of emergencies and provide patients with around-the-clock care.
During a hospital stay, the hospitalist will:
When the patient is discharged, the hospitalist will direct the patient back to their Rush Copley Medical Group primary care physician for all follow-up care.
View More
© Copyright 2020 Rush Copley Medical Center • 2000 Ogden Avenue; Aurora, IL 60504
Main: 630-978-6200 • Physician Referral & Information: 630-978-6700 or 866-4COPLEY (866-426-7539)


text:
Cover blurb:
One man alone knows that something's wrong: Maxwell Edison, Stockbridge's unofficial ambassador to the Universe. Or 'flying saucer nut', as the locals have it. He'll need help proving it: from the local postmistress Miss Nyssa, perhaps; or the village Doctor, the fellow that's been living at the Green Dragon Inn these last 30 years.
They'd better hope that autumn never comes to Stockbridge. When autumn comes, the world is doomed...
|Go back


text:
In Previous article, i have discussed the multiple times firing of telerik Rad Window and its solution at code side. (C#)
In this article i will provide solution of same problem in Javascript style. 🙂
How to set the problem of loading popup three time…
- Any page must have only one RadWindowManager, if have more than one manager then usually it sets the setting of first manager…. Ambiguity
- ReloadOnShow must be false. Instead of this use below technique.
Create a random javascript number and send as a URl parameter while opening from client side, in this way, it will ensure to load page with reload option. And therefore no need of this flag.
I have found that if the Reload is turned on, it will hit the window page twice for some reason (not desired). If you turn the Reload off though, it will never show the updated page if you are reusing the same window. So far, what seems to work best is to add a random number into the url so the window does not use a cached version (see below). It will only hit the page once, and will also actually display the new page.
Client side code:
// Need a random item in the querystring so the RadWindow does not pull from cache. var WinId = "Win" + Math.random().toString(); var Url = "query_preview.aspx?id=" + elReportSavedQueryID.value + "&wid=" + WinId; var oManager = GetRadWindowManager(); var oWnd = oManager.GetWindowByName("ExportPreviewWindow"); if (!oWnd){ alert("No window object found!"); return; } oWnd.SetUrl(Url); oWnd.Show();
Window Manager in Page:
<radw:radwindowmanager id="RadWindowManager1" runat="server" left="" navigateurl="" skinspath="~/RadControls/Window/Skins" title="" top=""> <Windows> <radW:RadWindow ID="ExportPreviewWindow" DestroyOnClose="false" Modal="true"EnableViewState="False" VisibleStatusbar="true" Width="600px" Height="400px" NavigateUrl="" /> </Windows> </radw:radwindowmanager>


text:
City College Norwich: Enter stage right
PUBLISHED: 17:50 20 December 2016
Laura Hodges of City College Norwich explains the qualities that a good performer needs and gives her advice on how to nurture a young person's talents
Winter is a time for visiting the theatre, and with the magic and excitement that each show or panto brings, there will be many young people in the audience hoping that, one day, they will be able to perform on stage.
Laura Hodges, professional theatrical and musical director, founder of the Norwich Young People's Theatre and course leader for City College Norwich's Musical Theatre courses, has helped many aspiring young stars to achieve their dreams in the performing arts. With more than 15 years' experience, Laura knows what it takes to be a good performer and how to become successful in the industry.
"A good performer needs to be fit, healthy and willing to work hard, but most importantly they need to be talented. Most theatrical directors, especially those who are involved in musical theatre, are looking for people who are what is known as 'a triple threat' performer, which means that they are gifted in singing, dancing and acting. However many are now also looking for a fourth threat, which can either be the ability to read music and play an instrument or being able to do gymnastics.
"The theatre industry is tough because everybody is very talented and it can sometimes be difficult to make yourself stand out, so getting your first big break is as much about luck as it is about your abilities. However, once you get your first big break, the main thing that will get you your second job is if you are a good person to work with, which is what is known in the industry as being a 'good company member'. Because of this, we always ensure that we teach our students the importance of being kind, on time, willing to help, and of supporting colleagues, alongside working with them to develop their existing talents.
"For those who are looking to nurture their child's gifts at a young age, my advice would be to only take them to dance, acting and singing classes if they're enjoying it. From my experience, I have found that young people who are being taken to classes that they don't like generally won't continue with them in later life. If classes are unavailable, watch the shows they want to put on at home and they will learn through those. If they choose to pursue their passions when they're older, studying a performing arts course at college is an ideal opportunity for them to hone their skills in their chosen specialism and gain valuable performance experience . This will allow them to study a wide variety of courses at drama school or university and bring them one step closer to achieving their dreams."


text:
Rumors EVERYWHERE
- The command staff is to report to HQ to get their digital radios with a special federal channel in case everything goes to Hell. (might be true)
- Cancelled days off and 12-hour days start as soon as closing arguments begin, maybe as soon as Wednesday, certainly by the weekend (probably true, but dictated by the pace of trial)
- The Jewels' store sent out a managers memo to put all shopping carts inside at night under lock and chain to discourage expected looters from carting out merchandise and limiting losses to hand carry. Also Oscos' will not restock any liquor this week and suspended all deliveries.(would be the smart thing to do, so maybe true)
- CPS will allow all student to participate in any manner of choosing to protest at anytime during school hours. Buses and free lunches will be provided.(so nutty it HAS to be true)
Labels: rumors


text:
KETE korero, the official newsletter of the Diocese of Hamilton, was launched in 1996, the fourth newsletter format since the first Hamilton Diocesan News was published in July 1982. The name KETE korero, meaning 'baskets of talk' was chosen by Bishop Takuira Mariu SM. Thanks to the generosity of sponsors and advertisers, KETE korero is delivered free of charge to all the parishes and several schools in the diocese.
To make news and information about the Diocese of Hamilton available to the people of the diocese, and to share stories about people, parishes, schools and groups.
To source news and information from as wide a base as possible, and to be as inclusive as limited space allows.
Organisations and individuals who have something of interest to contribute are urged to do the following:
· Let the editor know in advance that something is coming up.
· Advance information is preferred to reports that may be weeks old before they are published.
· Note that the length of the average story is short – long accounts of events will almost certainly be cut. Articles should be around 500 words.
· Photographs are appreciated provided they are clear and well lighted. Close-ups reproduce better than distance shots. People in groups should also be positioned close together, without wide gaps in between. Photographs may be sent as prints or digital files. The latter should be high quality and in jpg format.
· Information published in KETE korero are also published on the diocesan website.
The Editor
KETE korero
P O Box 4353, Hamilton East
Tel: 07 856 6989
Fax: 07 856 7035


text:
New fund tackling loneliness opens to applications
Posted: Mon, 23 Jul 2018 16:09
Charities and community groups in England can now apply for a share of close to £9 million aimed at tackling loneliness by building strong social connections and welcoming communities.
The money is from the £11.5 million Building Connections Fund announced on 19 June by the Prime Minister, Theresa May, and lead Minister for Tackling Loneliness, Tracey Crouch, in response to the Jo Cox Commission's recommendations on Loneliness.
Almost £9 million will be distributed by the Big Lottery Fund, the largest funder of community activity in the UK, and will support projects already working to prevent or reduce loneliness to increase their impact.
Grants of between £30,000 and £100,000 will be available for projects which reach out to people of all ages who feel lonely or isolated, and encourage them to take part in activities, helping them to feel more connected.
This could include making the most of community spaces, improving access to transport, using digital technology, or joining up local services to have a bigger reach.
Applications open Monday 16 July and will close on Friday 24 August. Guidance and criteria are available on the Big Lottery Fund website.
Minister for Loneliness, Tracey Crouch MP, said: "Loneliness is a serious issue that can affect anybody. Communities suffer when people feel disconnected or alone but by working together we can reduce its stigma and build on the legacy of Jo Cox.
"I encourage charities and community groups across the country to help us tackle loneliness. This fund will help improve people's lives and build stronger communities."
Dawn Austwick, Chief Executive of the Big Lottery Fund, said: "Feeling connected to the people around us can have a profound impact on our wellbeing, encouraging a sense of belonging and helping to prevent loneliness.
"That's why we're proud to be launching this new fund in partnership with Government and the Co-op Foundation. Thanks to funding raised by National Lottery players, it will help inspire community spirit and spark new friendships between people of all ages."
The remaining £2 million from the £11.5 million Building Connections Fund will be distributed by the Co-op Foundation, the UK's leading funder of projects tackling youth loneliness.
Grants of up to £80,000 will be available for youth organisations already helping young people avoid long-term loneliness.
Successful applicants will receive funding to explore youth loneliness in greater depth, test youth-led innovations within their current services, and share learning as part of the Co-op Foundation's national Belong network of youth partners.
Applications to this youth-focused strand of the Building Connections Fund will open in August 2018. Guidance and criteria are available on the Co-op Foundation website.
Groups should apply to the strand which is most appropriate to support their work.
All grants will be announced in December 2018, with funding available to support projects until March 2021.


text:
Oct. 19, 2020
From Central American beaches to African plains, Biola's Student Missionary Union (SMU) sent four teams of students overseas during Interterm to share the love of Christ. SMU commissioned teams to El Salvador, Swaziland, Thailand and Spain.
El Salvador 2012 from Cody Ramaekers on Vimeo.The team in El Salvador set out to equip fellow believers and share the gospel through a surfing ministry organized by a Christian family. Led by junior Cody Ramaekers and sophomore Christa Rorer, a group of eight ministered in this Central American nation. Kids from the area attended the camp to learn how to surf but they left with more than just refined surfing skills. The kids experienced the love of Christ through the Biolans who taught them. The team attended a Christian Surfers International meeting, traveled to local orphanages and saw many friendships form with the locals.
The four teams will share their collections of photos and many stories at "Pix 'n Pizza" on Feb. 12, 2012 at 6 p.m. in the Cafeteria Banquet room.
See an overview of the four trips, with introductions to each leader, here.
Written by Abbey Bennett, Media Relations Intern. For more information, contact Jenna Bartlo, Media Relations Coordinator, at 562.777.4061 or at firstname.lastname@example.com.
Manager of Media Relations
Director of Communications
media [dot] relations [at] biola [dot] edu


text: Full_Name: Pierangelo Masarati Version: HEAD/2.3 OS: Linux URL: ftp://ftp.openldap.org/incoming/ Submission from: (NULL) (220.127.116.11) run test010 with -b ldif; this causes back-ldif's get_entry() to call dnParent() with the o_req_dn in non-normalized/pretty form (in detail, with a space " " following a comma ",": "cn=smd5, dc=example,dc=com") that causes an assertion fault. The function passwd_extop() doesn't pretty/normalize the o_req_dn field. I've fixed it in HEAD. This error may impact other backends, and thus 2.2 as well; however, it appears that o_req_dn is never used in those cases. p.


text:
Aune history
Aune is the brand of the largest Chinese audio technology community HIFIDIY.NET (2004-2014), which had ten years of histroy In the past ten years, they have accumulated a large number of excellent designs. High performance and high quality is aune's pursuit, it is our first time to coming into Europe, hoping aune products can bring you happiness!
Aune Audio, a Chinese audio brand, has taken the audio world by storm with its highly durable and pocket-friendly audio devices. Hi-Res audio players are specially designed to produce high-resolution sound through your high impedance headphones and earphones. TechnoVolume brings to you the best Aune Audio Hi-Res audio players, at the best prices online. These audio players feature DSD technology, stable power supply, HiFi components, and more. Aune Audio is an audiophile grade audio player that converts digital audio into a high resolution analog sound. We have a wide range of Hi-Res audio players that fit every buyer's need and budget, from the best brands across the world. Plug in and enjoy a louder and better music experience with sound clarity that makes you feel like you're in a studio. Buy the best Aune Audio Hi-Res audio player from TechnoVolume at the most affordable prices.
Aune Audio Europe is official EU Netherlands distributor for Aune. Our products are distinguished in the absolute sense in pure sound quality and finish and thus fit into our philosophy. The brands on this website like Aune Audio had chosen to sell there products not through a dealer network but to have only one sole distributor and direct salespoint.
Aune Wuhan AO LAI ER Technology Co.ltd company is one of China's first dedicated high-quality digital audio company, it is a development and manufacture of integrated enterprise, with high-end design team unity, excellent operational management team. Full of scientific and technological innovation mission, we are constantly exploring different solutions in the high-quality digital audio field.
Aune are not only the first launched mastering digital audio player in China, launched its supporting 32bit/192kHz advanced decoder and peripheral products, but also supporting the development of personal computers around the traditional audio equipment, developed a high-quality USB decoder and the traditional CD turntable.
In addition to the innovation of R&D, from operations to customer service, from product manufacturing to the user manual, every detail, Aune pursue excellence. Brand firmly believe that the "pursuit of perfection" is endless. Meanwhile, Aune company's HIFIDIY.NET as the sound field to focus on portal – since 2004 to become the largest Chinese audio site and community, with nearly 1,00,00,00 members. It is the foundation of Aune brand rooted, making Aune brand has extensive influence in the Chinese community, received numerous accolades.


text:
Here are the three best things you can do in December to help grow your print and mail business in 2017:
- Embrace and become highly proficient with LinkedIn (LI). With almost 500 million users, LI is today's professional network and the best place to expand your reach, promote your personal brand, stay top of mind and generate traffic to your company website. Think you already have it down? What about LI Showcase or LI Sales Navigator? There are so many tools and strategies to explore. I just did a webinar for PIA on this topic. Reach out if you would like to discuss this.
- Develop a customer retention program. All sales growth begins with retention. It's less costly to keep an existing client than to cultivate a new one. Follow the 90 day rule. Use a multi-channel strategy to engage each of your customers at least 4 times per year (good marketers shorten this to 30 days) in a non-selling manner. A company newsletter or magazine, customer education events such as a webinar or lunch and learn, brief email notifications that present useful, customer focused content, customer appreciation events, etc.
- Learn marketing. It's no longer about learning to be a great closer or prospector. The most important trait a salesperson can have today is to be a good marketer. Smart marketing increases sales reach and effectiveness. Join marketing associations and LI marketing groups. Sign up for various marketing newsletters- there is a wealth of highly relevant information right at your fingertips! Being a smart marketer will also allow you to provide greater value to your customers and prospects.
Thanks to PIA for the opportunity to present to their members and thank you to my many loyal clients who utilize my company's marketing services. If anyone would like information on our turn-key marketing solutions, please visit us on the web and submit a sample request. Cheers to a safe and joyous holiday season!


text:
I-Motion Gym
I-Motion started in November 2010 with a great idea of providing high quality service and equipment to the public with the vision of refreshing the concept of fitness. We put together a team of experienced and dynamic people to reach the objectives we have set at that time. All objectives were reached rapidly and it was time to rethink the way we wanted people to be aware of their health and actions they can take to seek a better mental and physical condition. This never ending goal makes I-Motion a continuously evolving company being now main actor of the fitness industry in Mauritius and a trend setter toward competitors.
Group Class Studio
The multipurpose studio gives you a wide range of possibilities from Karate classes, Yoga, Zumba, Belly Dancing to Circuit training. See the group classes schedule to see what's on and call our team on 468 11 11 for more info or for a trial.
Corporate Gym Services
I-Motion is the main actor of fitness and gym solutions for the corporate. Our team can guide you for a corporate fitness solution: - Gym membership for your staff - Group classes for your associates - Creation of a gym in your premises - Supplying of fitness equipment and coaches to your premises


text:
Ops Engineer (Swift Squad)
Empployé / CDI | Technologies de l'information | Expérimentés | Belgique | G | 2020-09-10 | 059146
Are you looking for a position of OPS engineer?
A position in which you can integrate any application on our RHEL7 systems, scoping from OS up to application configuration.
The SWIFT squad is primarily based on a product centric model based on standard IT deliverables. The squad has an incontestable client focus dealing with several hierarchical levels, geographical zones (locations and branches) and numerous stakeholders.
The systems and the team are seen as one entity part of the global SWIFT competence centre for the ING Group. We deliver our services world-wide, for Americas over Europe across Asia till Australia.
Are you someone who is …
- proactive and result-oriented
- analytical and strong in problem-solving
- multi-tasking and able to work in AGILE environment
- has a hands-on mentality, well organized, able to take up ownership and see things to the end
- communicates clearly, is able to present concepts, data and issues in a structured way
- Be organized, responsive and a team player with positive and constructive attitude
- Be self-motivated and able to work without close supervision
- Be professional, resourceful and accountable
We look for
A colleague with a talent for taking it on and making it happen, enthusiasm for helping others to be successful and always being a step ahead. In other words, you strive to keep the job done and embrace challenges in a fast changing and complex environment. You are a naturally collaborative person who listens and invests in others to achieve common goals. You love to challenge the status quo and are eager to propose creative solutions to problems.
As an OPS engineer to integrate new application on our systems, for the SWIFT squad you will need to:
- Be educated in computer software engineering or a proven minimum 5 years professional experience dealing with maintenance of IT assets.
- Good knowledge on Linux distro(RHEL7,….)
- SWIFT application and general knowledge about SWIFT are added-values, but not mandatory.
- Web Application Server, network load balancers, ... are added values.
- Education background with application development appreciated.
- Have strong analytical and problem solving skills
- Capabilities to document newly designed functionalities, technical writing skills.
- Good knowledge of English (also French and/or Dutch is considered as an asset)
- Adhere to the agile philosophy and the DevOps concept
Plus d'informations


text:
The New Year kicked off with a lot of exclusive biotech news and features, and next week will be even busier when I'm attending next week's JP Morgan Healthcare Conference in San Francisco.
—Alder Biopharmaceuticals was one of the Seattle biotech companies that emerged in 2009, but few people realize what humble beginnings it had six years ago when all the founders lost their jobs in a downsizing at Celltech. We published the story of how they bootstrapped the Bothell, WA-based company for its first 20 months, putting it on a course to snag a $1 billion partnership with Bristol-Myers Squibb.
—Seattle-based ZymoGenetics (NASDAQ: ZGEN) saw its stock double in 2009, and this week it decided to seize on that growing interest to hit up investors for more cash. The company ended up netting $79 million after expenses from an underwritten stock offering. It plans to use the money for R&D, and to inject some life into its lone marketed product, recombinant thrombin for surgical bleeding.
—Bothell,WA-based Halosource, the developer of a cheap and simple technology for purifying water in developing countries, said it has raised $10 million in a new equity financing. The company has gotten some momentum with more than 4 million people using its technology in India, and it plans to use the money to expand further in other countries.
—Antibody drugs that target diseased cells and spare healthy ones have been one of the big successes in biotech, but Seattle Genetics (NASDAQ: SGEN) says it's not really the cutting edge anymore. The Bothell, WA-based company's CEO, Clay Siegall, says it is "unlikely" it will introduce any more plain antibodies into clinical trials, and that the future will belong to antibodies that are "empowered" to be more potent.
—We had a number of insightful guest editorials. Stephen Friend, the founder and CEO of Sage Bionetworks, offered his view of five biotechnologies that will fade away this decade. Bob Nelsen of Arch Venture Partners chimed in with his top five innovations to watch during the '10s (or whatever we're calling this decade). And Stewart Lyman looked back at the year that was in Seattle biotech.
—Stratos Genomics, the Seattle-based developer of a faster and cheaper DNA sequencing technology, has received three months of access to a microfabrication laboratory at the Washington Technology Center on the University of Washington campus. This was part of a stimulus program for small technology businesses in Washington state.


text:
My first poop video ever. Preparing a special treat for a toilet slave of mine. First I strip then I tease with my feet, pussy, and asshole. You know you want to suck these toes and lick my private parts… I pee into a Tupperware jar first. Then I make my chocolate onto a plate which I then pick up with a glove and put it into another Tupperware. My sub is in for a very special treat!
Length: 6:09s Resolution: 1920x1080Download Format: mp4File Size: 247 MB


text:
Published in The Hindu on October 22, 2009
The results of the Phase III AIDS vaccine trial using a prime-boost (ALVAC and AIDSVAX) vaccine undertaken in Thailand, published in The New England Journal of Medicine (NEJM), show that the vaccine is able to produce 31.2 per cent protection in those who are not infected at the time of enrolment.
This is the first time ever that a vaccine has been able to provide statistically significant protection. The trial was conducted on nearly 16,500 volunteers.
Despite this good news, the results clearly show that the vaccine cannot be used as a public health control measure.
That is because the volunteers primarily belonged to the low- and moderate-risk groups that were at risk of being infected through the heterosexual route. Nearly 48 per cent of the volunteers belonged to the low-risk group and 28 per cent belonged to the moderate-risk group.
The reality
The authors claim that the prime-boost vaccine tested "may reduce the risk of HIV infection in a community-based population with largely heterosexual risk." But the Editorial published in the same issue of the journal makes it very clear that it cannot be used for public health control. "The vaccine regimen studied is unlikely to be a public health control measure for HIV-1 infection," notes the Editorial.
Additionally, the researchers found that the duration of immune response, and hence protection offered, may have decreased in the first year after vaccination.
This is despite the fact that the vaccine tested was a prime-boost combination and six injections (four to prime the immune response and two to boost it) were administered.
They also found that the vaccine efficacy (ability to protect against HIV infection) was greater in people who were at low risk for infection. An acceptable vaccine for public health control will be the one that provides more statistically significant level of protection to both the high-risk and the low-risk groups.
The Editorial notes that the trial has brought out the fact that the "requirements for protection against transmission in low-risk, heterosexual persons are considerably different or less stringent than in high-risk subjects." That could be the silver lining for further research in AIDS vaccine.
Unexpected result
Though both the vaccines failed when used alone in trials conducted earlier, the combination has been found to provide nearly 31 per cent protection. That appeared strange to many people working with AIDS vaccine.
However, the researchers have not been able to find the answer to how the combination protected some of the individuals. They note that the data was not able to answer the "related question of whether it was a single vaccine or the combination of vaccines that induced a potentially protective immune response."
A prime-boost combination is supposed to produce qualitative or quantitative protective immune response that is not otherwise seen when the vaccines are administered alone.
But the study data has not addressed this important issue. Despite the several shortcomings and limitations, the trial has provided the much needed hope for future work on AIDS vaccine.


text:
Sienna Miller on her flight from Hitchcock
The Hollywood actress discusses how she drew on her own traumas to play Tippi Hedren, a woman wooed and then broken by Alfred Hitchcock
For the past decade Sienna Miller has been trapped in the headlines, not so much for her films (Factory Girl, Layer Cake) but cast variously as Jude Law's scorned fiancée, a paparazzi magnet, a cool fashion designer, a star in a reasonably priced car on Top Gear and a standard-bearer against press intrusion.
But now she is content as a new mother. "My life is really different: it's much better," says the actress of her latest role as mum to baby Marlowe, the daughter she had in July with her fiancé, actor Tom Sturridge.
"People told me not to have kids, but I think motherhood's got a bad rep – I don't feel compromised. In fact, I don't want to be anywhere else except with her."
When we first met, Miller was three months pregnant, and in the middle of a brutal shooting schedule for The Girl, which tells the story of Alfred Hitchcock's obsession with Tippi Hedren, the model he cast in his 1963 film The Birds after seeing her in a TV commercial.
"I think he wanted to create his ideal blonde, his ideal woman," says Miller. "He found this unknown so that he could mould her. Initially she trusted him. Then it started to get really weird." Weird meant manipulative, lewd and, finally, vindictive.
For the famous scene in The Birds where Hedren's character Melanie Daniels is attacked in an attic, Hitchcock had live birds wired into Hedren's clothing. One of them gouged her cheek; Hitch had told her they would be using mechanical models. Hedren's attic-scene ordeal lasted for five days.
For their next film, Marnie, Hitchcock insisted on a rape scene, against his producers' advice. When she still rebuffed him, Hitchcock kept her under contract for a full seven years, but never cast her again, effectively ruining her career.
Tippi Hedren lives in California these days, running a sanctuary for big cats. Miller was summoned to meet her.
"I think she wanted to make sure that physically I fitted the mould. She said that a lot of actresses are so tall and athletic now – and I'm not athletic at all.
"And she was worried that an English person was playing her, until I said I'd played more Americans [Miller has an American father and dual nationality]. In the end she was happy that I was doing it. We've spoken on the phone a lot and she's been great."
While re-enacting the making of The Birds, Miller had to endure many of the things that Hedren did. "I did go through a bird attack for two hours. It pales in comparison to what she was subjected to, but it was pretty horrible. There were men in off-camera with boxes of birds, throwing seagulls and pigeons in my face."
Hedren was in her early 30s when she made The Birds; Miller is 30; both started out as models and achieved fame in ways they never foresaw; and both found themselves at the mercy of controlling men.
In Miller's case, it was photographers – she told the Leveson Inquiry that she was often pursued by ten to 15 of them, verbally abusing her and trying to get "an emotional reaction". At the height of his obsession, Hitchcock paid henchmen to follow Hedren and report back.
Miller plays down the comparison, but appreciates Hedren's ordeal. "Initially that kind of attention is very flattering. Then the next thing you know there are people following you and you're being asked what you're doing out with this person. Suddenly you're into something you had no idea you were walking into, and it's too late to get out."
The Girl will be broadcast tonight at 9:00pm on BBC2