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Laptev Sea
The Birthplace of Arctic Sea Ice
For the past several years, the expanse of sea ice in the Arctic has melted more and more intensively during the summer months. To determine whether, and if so how, this trend will continue, we have to first better understand the processes involved in the formation and disappearance of sea ice. With that goal in mind, AWI researchers like the sea-ice physicist Thomas Krumpen are now especially exploring a region considered to be the ice machine of the Arctic – the Laptev Sea in northeast Siberia.
When Thomas Krumpen flies over the Laptev Sea in springtime, the AWI researcher sees nothing but ice. The sea off the coast of Siberia looks like a splintered pane of frosted glass, a chaotic mosaic of jagged fragments in countless shades of grey and white. The Laptev Sea is essentially the birthplace of Arctic sea ice. Here, in the remote northeast reaches of Russia, during the winter the wind incessantly blows from land out to sea. It pushes against the ice floes in the water, driving them forward - away from the shore and due north. As a result, the ice cover near the coast is increasingly broken up, briefly leaving behind areas of open water referred to as polynyas. But when exposed to the wintry air, which can be as much as 40 degrees below zero Celsius, they quickly refreeze. A thin sheen of ice is created, only to be broken up and then blown onward by the wind... This process constantly produces new sea ice in the Laptev Sea, which then finds its way to the Arctic Ocean. The Arctic ice machine only shuts down in May, when even northeast Siberia grows warmer - and starts back up in early October, when the icy winter winds return.
Sea-ice researcher Thomas Krumpen knows this interplay of frost, wind and water inside and out. Together with peers from the GEOMAR Helmholtz Centre for Ocean Research (Kiel) and experts from Russia's Arctic and Antarctic Research Institute (AARI, St. Petersburg), he conducts experiments in the Laptev Sea area on a regular basis. One of Krumpen's goals is to find answers to the question of why Arctic sea ice is melting more and more each summer. Over the past 25 years, the summer ice cover has shrunk from 8 million to 5 million square kilometres. "Like many other researchers, we're convinced that the increased melting is due to climate change. Our current goal is to better grasp the physical interactions between the sea ice and the Arctic Ocean, those between the sea ice and the atmosphere, and how these processes will change in connection with global warming," explains Thomas Krumpen.
The retreat of the Arctic Sea Ice Cover over time
The ice's journey ends in the Fram Strait
Research efforts in the Laptev Sea offer clues as to how much new ice is formed each winter. But in order to assess the fate of the Arctic sea ice, the researchers also need to determine how much ice flows back out of the Sea. One of the most important outlets is the Fram Strait – the sea lane between Greenland and Svalbard. Each year, between 500,000 and 800,000 square kilometres of sea ice – an area roughly twice the size of Germany – flow through the strait from the Arctic Ocean to the northern Atlantic.
The motor of this ice transport is the transpolar drift, a major current that pushes ice from the Russian marginal seas of the Arctic Ocean over the North Pole and toward the Fram Strait like a giant conveyor belt. "We are working to better estimate the ice mass balance in the Arctic by examining two factors – how ice is created in the Laptev Sea, and how it is lost again via the Fram Strait – in relation to one another," says Thomas Krumpen.
As a rule, it is only the sea ice formed in the Laptev Sea in the early winter that survives its first summer. Caught by the transpolar drift, it is transported to the central Arctic. Once there, it can remain two to three years, growing to several-metre-thick pack ice in the process, before passing through the Fram Strait and into the Atlantic, where it melts. In contrast, the ice formed in the late winter usually melts before it can flow out of the Laptev Sea.
Over the past several years, Thomas Krumpen and his colleague Stefan Hendricks have regularly taken part in plane or helicopter flights over the Laptev Sea and the Fram Strait. During these flights they rely on the EM-Bird, a device that can measure differences in electrical conductivity from the air, allowing it to determine how thick the ice is.
Old ice in Arctic vanishingly rare
Since the 1980s, the amount of perennial ice in the Arctic has declined. This animation tracks the relative amount of ice of different ages from 1987 through early November 2014. The oldest ice is white; the youngest (seasonal) ice is dark blue. Key patterns are the export of ice from the Arctic through Fram Strait and the melting of old ice as it passes through the warm waters of the Beaufort Sea. (Animation by NOAA Climate.gov team)
Early warning signs of the great melting
The AWI sea-ice physicist conducted one such measuring campaign in the much-cited record year 2012, in which the Arctic sea-ice cover shrank to only 3.4 million square kilometres, the smallest expanse recorded since the advent of satellite measuring in 1979.
In a sense, Thomas Krumpen had seen the negative record year coming: in March 2012 he and partners from the Russian-German research project "System Laptev Sea" had made flights over the Laptev Sea and discovered surprising quantities of thin ice. "In places where the sea ice had been up to 1.5 metres thick in the winter of 2007/2008, in the spring of 2012 we encountered stretches up to 400 kilometres across where the ice was only 50 centimetres thick. This allowed us to safely assume that above all the ice in the Laptev Sea region would largely melt away by the end of the summer," he explains.
The amount of old, thick ice in the central Arctic has been dwindling for years thanks to global warming, which has increased the sea ice's drift speed. As a result, more and more ice is flowing out of the Laptev Sea. When this is combined with strong offshore winds, like those in the winter of 2012, huge stretches of thin ice form, only to rapidly melt away come spring.
This melting is accelerated further by the fact that in summer the dark stretches of open water warm much faster than the sea ice. "This warm water intensifies the melting of the remaining ice, an effect we've been able to clearly observe since 2012. For example the Northeast passage, the shipping route leading from the northern Atlantic and along the Siberian coast to the Pacific, was free of ice relatively early in the year," says Thomas Krumpen.
Sentinels on the seafloor
The sea-ice physicist and his colleague Polona Itkin have now succeeded in reconstructing observations of the Laptev Sea with the help of mathematical models and satellite data. By doing so, they have confirmed what had long been only a theory, namely that the ice formed in the Laptev Sea during the winter and early spring plays a key role in determining the fate of Arctic ice in the Northeast passage once the summer comes.
"Now we're interested in how these processes in the Laptev Sea affect the overall volume of ice in the Arctic, because that volume, which depends on both the thickness and the area, is already in decline," claims Thomas Krumpen. According to the AWI researchers' models and measurements, the amount of ice exported from the Laptev Sea appears to be increasing, because the young, thin ice is quickly carried away.
In order to validate their model, the researchers need to gather additional data. With that goal in mind, in 2013 Thomas Krumpen and Stefan Hendricks installed buoys at two points in the Laptev Sea. Anchored to the seafloor, the buoys are equipped with an Upward-looking Sonar (ULS) system, which consists of a transmitter that sends acoustic signals up toward the water's surface. If it encounters ice, the distance travelled by the signal is correspondingly shorter, making it possible to determine how thick the ice is. Unlike flights with the EM-Bird, this method allows the researchers to collect data on a single location for weeks or even months at a time.
Flying halfway around the globe: measuring sea-ice thickness in the Arctic
Anyone who wants to accurately predict the summer ice extent in the Arctic has to first know how thick the ice is at the end of the long winter, which is why the AWI sea-ice physicists set out each spring to measure major sections of the Arctic sea-ice cover. Their flight route usually begins in Svalbard, taking them west over Greenland and Canada and ending in Alaska. The following gallery presents a selection of snapshots taken during flights in the spring of 2015 as part of the NETCARE campaign.
In the air from Svalbard to Canada
As in the Laptev Sea, ice export is also increasing in the Fram Strait. This is indicated by satellite data, which can be used to determine ice drift and concentration. The AWI researchers have also observed that the thickness of sea ice in the Fram Strait has decreased significantly. Together with their American, Canadian and Norwegian peers, Thomas Krumpen and Stefan Hendricks are working to gather the requisite data in measuring flights for the project PAMARCMIP (Polar Airborne Measurements and Arctic Regional Climate Model Simulation Project). For this research campaign, every spring the researchers fly a route starting in Svalbard, continuing over the Fram Strait to Greenland and ultimately to the western coast of Canada, measuring the ice thickness for spans measuring hundreds of kilometres. "But at this time, we still can't say to what extent the increased ice export in the Fram Strait will be compensated for by the lower ice thickness," says Thomas Krumpen.
A further open question is how the altered ice mass balance – the increased export from the Laptev Sea and the Fram Strait – will affect the Arctic as a whole. According to Thomas Krumpen: "The trend of summer ice loss can clearly be recognised – but whether the Arctic will be completely ice-free in the summer, and if so, in how many years, is something we'll only be able to say once we better understand the sea ice."


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I'm looking for ways to manage the installation of non-distro software, with multiple versions of the same software installed simultaneously. For example we'd have ProgramA 1.6 and ProgramB 1.7 installed simultaneously, and users would be able to switch between them.
A common solution to this seems to be environment modules which I know is used with success at many academic sites. Users can then just run
module load ProgramA/1.6 and then running
ProgramA would get them the right version. So conceptually I can maintain a repository of all the modulefiles which users would use to activate the right environment.
My problem lies mostly with creating a reproducible way to actually build the software used by the modules. I'd need a reproducible way to build each software package. What would be a good way to do this? Is it possible to achieve with RPMs in an alternate root location and/or alternate RPM db? Is there another tool I could use to manage the software builds? Should I just cobble it together with shell scripts?
The platform we're running on is Scientific Linux 6, which is basically equivalent to Red Hat 6.

subset: commoncrawl


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You might have seen this quote on Instagram before; "The day you plant the seed is not the day you eat the fruit". This is so true, and such an important reminder to keep in mind. This applies to all things in life. Things do take time, and a continuous effort.
You might want to grow a business. This doesn't happen over night. It takes time and effort. You can start to plant the seed for it, by starting a website or a blog – but that is not enough for you to have a business. You need to continuously water and nurture it, in order to make it grow.
The same goes for many other things in life. If you want a good relationship, you need to continuously water & nurture it. Put in the effort, plan dates, communicate also when things gets hard, do loving things for each other.
Whatever you want to see grow in your life – you need to give attention to, and water and nurture it, otherwise the seed will die out. But if you keep watering it and giving it love and attention, I promise you, one day the seed will have grown big and beautiful and you will be able to reap all the rewards from all the love, attention and dedication you put into it ✨
But remember, in order to grow anything, you also first need to plant the seed. If you want anything in life, you need to plant the intention of it, start it and then you can start to water it.


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Next Free Parker Mills Ethics MCLE Program: February 15, 2017
The next free Parker Mills MCLE legal ethics lunch and program is Wednesday February 15 from noon to 1:00 p.m.
The continuing education reporting deadline for attorneys in Group 3 (last names beginning with "N" through "Z") has been extend to March 1, 2017. The February 15 program qualifies for 1 hour of legal ethics continuing education credit.
To attend this free lunch and program, please RSVP by noon, Monday, February 13. Contact Christina Quintero, firstname.lastname@example.com, 213-622-4441. Space is limited.
Location: Parker Mills LLP
800 West 6th Street, Suite 500
Los Angeles, CA 90017-2702


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GCRF Establishment of biopharmaceutical and animal vaccine production capacity in Thailand and neighbouring SE Asian countries
Lead organisation: University of Kent
LSHTM staff : Prof Richard Coker , Dr.Fatim Lakha
Collaborating organisations: LSHTM, UCL, BIOTEC, Imperial College London, National Biopharmaceutical Facility
Support by: GCRF – Global Challenges Research Fund
Project aims:
To produce life-saving Biopharmaceuticals in Thailand for the first time at a cost that allows wide access to patients.
To produce a suite of veterinary vaccines against the major porcine disease that will be made available to farms in Thailand, resulting in a sustained reduction in livestock losses.
To establish state of the art technical capacity for recombinant protein production by Thai groups, which can be expanded upon and consolidated for future growth.
To give neighbouring SE Asian countries full access to the programme's technology and expertise in order to effectively plan similar ventures.
This project brings together Thai groups at the forefront of the country's new programme to produce recombinant proteins, UK groups that have developed state of the art E. coli- and CHO cell-based expressed systems as well as down-stream processing and analytic tools, and Bangkok-based UK specialists in SE Asian healthcare, economic policies and dissemination tools.
This work is funded by the Global Challenges Research Fund and will contribute towards several UN Sustainable Development Goals:
Zero hunger
No poverty
Good health and well-being
Industry, innovation and infrastructure
Please visit the website here.


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(I have left Keri's responses in this where it does not give her away.) I look up to you as we lay there in a mess of sweat. "oh yes Daddy, i did like what she did to me. I smile remembering her licking and sucking my cum out of you. You had looked a little dazed. You did cum so nice that first time. I must have filled you completely too. I have never been touched like that before. so soft and gently, it was like she knew my body better than i did.
When i felt her mouth wrapped around me, I almost blacked out, her movements were so smooth. I wanted to tell her to do something, but when i thought about it, she did it.
It was like she was in my head. my pussy was made so wet by her, that I longed for more of her. i still think about her Daddy, and wonder if she would be interested in me again.
or if she doesn't' like me at all." 'Sheela will do as I want'. 'But she does want you baby girl, she tells me on the phone'. 'I will think about it sweet baby'. 'Right now I want to make you mine and not share you at all'.
'I have made you a woman and want to teach you all there is about love'. 'You are so precious my darling'. I stroke your back and naked bottom, little kisses, loving to sip your lips.
'Daddy, am I going to have a baby now'? I chuckle, 'No Keri, not yet'. 'Someday when we both want you to'. 'Now just enjoy school and being my secret love'.
'You are my love you know, my most precious and wonderful love'. 'How do you feel about me doing this to Sheela and to Mommy'? 'I have to do it to Mommy because we are married and she likes it when she is not mad at me'. 'Sheela, I will do only when I cannot have you baby'.
You giggle a little, 'I can hear you an Mommy sometimes, now I know why she makes those sounds'. 'I don't like it when you and Mommy fight'. 'I think Mommy is so pretty, I wish she liked to do it to me like Sheela'. 'Will you let me watch you and Sheela'?
'The idea excites me Daddy'. 'Yes baby girl, when I decide to let her kiss you again'. One more squeeze of your little body, a long kiss and I say, 'Time for a bath now baby girl'. 'I have something special for us'. I help you up from the couch and we go to the bed master bath. You pick out the soaps, oils and salts you like.
Mom lets you bath in it all the time so there are hers and yours. Some things you share. I get my safety razor and soap. I want to shave again before we loose ourselves in our lovemaking.
I like your pretty face natural and not hot red from my whiskers. A few kisses are exchanged before I help you in to sit facing me with your legs over mine. I open the frozen bottle of Spumante, fill a large frozen glass and we take sips, sharing the glass. You like it as we always let you have some at holidays. You know that mom and I take to this very bath often too.
Just not very often lately. I soak my face with hot water and lather up. I put some on your delicious nose too and make you giggle. I can see in the mirrors on the sauna walls and I make you help me.
Showing you how to shave all my little niches. I tell you how my mother would shave my father sometimes. He was half French and he would coo loving words to her as she shaved him.
I can feel the lips of your sweet pussy as my hard knob kisses them under the water. Finished, all the shaving creme gone you kiss me in all the nice places on my face.
Enjoying how smooth my skin is now. I adore you with my eyes and my hands massage your sweet little butt as we begin to play. I pour our glass full of the slushy Spumante and we begin to neck softly. Your hand pumping my dick slowly.
Your lips so sweet to kiss tenderly. We do not rush now. We have all the time in the world and we both want to get me inside you again but slowly to let your tight little pussy enjoy it and stretch to accept me. 'You are so beautiful Keri'. 'You are the most beautiful girl in the world'. That may be a stretch but you have got to be close. Perfect breasts, firm curved body, lovely smooth legs, angelic face, long dark brown hair and the sweetest little bottom anywhere.
All surrounding a tight little bare pussy that loves to cum. I am so lucky. I have you and you have me. Nothing can take you away from me now. Nothing! I bath you. Using the soft sponge I rinse my cum off your pretty face and neck.
Your hand under the water already working to get me hard and succeeding quickly. You have me throbbing in your small hand and it is straining to kiss your little pussy so close to it. Rinsing your shoulders, I admire their shape and how firm your body is. I rub and rinse your back. So nice, I will kiss your back from your neck to your butt when I have you in bed.
Even if I fuck you here in the tub I will want to fuck you for a long time again before sleep. Mmmmm.
You are the most delicious thing I have ever had and Kan was so special when she was young too. Her body had not had the benefit of good nutrition and healthy exercise like yours has always had. Now for those two wonderful breasts. They are going to be quite large I think. So high and firm now.
You are larger than most Asian women already. I daydream of the day I will see my child nursing from those breasts too. Not for a long time but someday. Giving eat breast its due attention, sucking each nipple, the skin under them and the curve up to your nipples I move my washing down to your tummy.
Leaning you back so that my dick rubs your pussy's lips while I rinse your abdomen slowly. Loving you, my eyes drinking you in. You take my dick and open your pussy with my knob. 'Careful baby girl'. 'You may be too sore'. You kiss me and frown a little as you carefully get my knob in. 'Oh Daddy, oh yes Daddy'. You whimper as you work me half way into you.
Your pussy wanting to swallow my dick so bad but being careful to not make it hurt. 'Daddy, I know you don't like dirty words but can I say some of them when we do this'? You sound a little out of breath as you begin to move up and down on me slowly. You tight pussy getting wetter to take my hard dick deep inside you.
'What words or those baby girl'? 'You can say anything you want now darling'. 'You are a woman now and my woman'. 'I love you and I love everything about you Keri'.
You close your eyes. Feeling me thrust up to meet you. 'Oh Daddy, it feels so good to fuck you'! 'I want to fuck you forever'. 'Never stop fucking me Daddy please'. I kiss you tenderly, push my dick hard into you. 'You can fuck me all you want sweet baby girl'.
'I love to fuck you too'. 'More than anything I love to fuck my sweet daughter, Keri'. I gasp as your pussy grabs me so hard. You using me. Building toward another wonderful cum. 'I will never just fuck you baby'. 'I love you too much and love making you feel good, making you feel loved as a woman and making you cum and cum'. We are thrusting faster now. I thrust up as you come down. You are using all my dick, going up till only my knob keeps you open then pushing down hard to grind your pussy on me.
I am controlling myself. When you cum this time I plan to carry you to bed and continue fucking you till you cannot cum any more. I hold you tight, gentle kisses till your breathing is back to normal. Leaning you back so I can see me in you. It is such a turn on.
My dick completely fills you. Your lips stretched to take it in you. So wet with your cum now, so hot and tight still. I must thrust into you a few times before taking me out of you. I stand in the water and help you up.
Using the sprayer we rinse all the soap off of us and step out on the rug as the water drains away. We finish the wine as we dry each other. You kneel to love my dick with your mouth for awhile. Looking up at me with your smokey brown eyes as you squeeze me with your lips and tongue.
I press my finger into your tiny anus. You jerk and open your eyes. 'Oh Daddy, are you going to fuck me there'? 'No baby girl, your pussy is too good to think of that yet'.
'I want you to give that to Daddy someday but not now'. I am having to grit my teeth to keep control. You have the best feeling body I have ever known.
Eyes closed again, my hot lips on yours, you cum. So sweet this time. So out of breath and so long. Your pussy devouring my dick. Using it, loving it so good. I am so glad you can take my dick, enjoy it. I know I will have you sore again by tomorrow but it will heal and quickly.


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Rose Darling Black Off Shoulder Ruched Stretch Mesh Dress
$109 $129
Sku: 2185MCBlack25
An update to everyone's favorite off the shoulder ruched dress is now available in black. Keeping the nude lining and the invisible zipper. The new color update has a black lace up sleeve to match the black ruched. Complete the look with a nude pump and a nude over coat.
- Materials: Stretch Mesh
- Clean: Dry-clean only
- Length:Length: Approx 27inch / 70cm


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I'm looking for help with troubleshooting people-picker in multi-domain environment with one-way trusts. We already executed the
stsadm –o setapppassword -password pickapassword
stsadm -o setproperty -url http://server:port -pn peoplepicker-searchadforests commands.
Before these commands were executed people-picker could find users from the local sharepoint domain. After running the commands, people-picker shows "callback error" immediately upon launching search.
Any ideas?


text: This informative reference reveals how Voice over Wi-Fi is a scalable, secure networking solution that supports today's demanding application needs. The book explains the ins and outs of the 802.11 standard, Softswitch architecture and applications, and related transport network technology so you can deploy full-featured Wi-Fi that has optimum range and signaling. You also learn the economics of 802.11 and Softswitch so you can measure the cost savings and return on investment of deploying Wi-Fi.


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Just ANOTHER reason to choose
Silver Springs Water® in Las Vegas & San Diego
Silver Springs Water will beat any competitors price. Simply show us any advertised price or invoice from any competing water delivery service and, we will meet or beat that price with our best selling or our premium water.
Remember another benefit to doing business with Silver Springs Water, is that we NEVER make anyone sign a ridiculous contract to start water service! Just another reason that makes Silver Springs Water the best water service on the planet. Voted My Vegas Magazines top 30 businesses in Las Vegas!


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Perming hair changes the texture of your hair by using waving or straightening lotions. These chemicals break the natural bonds in the hair shaft to allow your hair stylist to form your hair into its new texture whether curly, wavy or straight. The strong chemicals used to break these bonds strip the hair's cuticle, leaving it drier and more prone to frizz after processing. Take special care of permed hair in order to maintain shiny, healthy hair.
Wash and condition your hair using shampoo and conditioner designed specifically for permed or color-treated hair. These products nourish your hair and return moisture to the shaft, which will help to reduce frizz and improve the texture of your hair.
Allow your hair to air dry or, if not possible, dry your hair using a hair dryer with a diffuser nozzle. Heat styling dries out your hair and causes damage, which leads to frizz and breakage. If you absolutely need to blow-dry your hair, use a diffuser to spread the heat and reduce damage.
Apply a smoothing serum to your dry hair. Place a small amount of serum in your palm, and then run your hands and fingers through your hair. Silicone-based serums will smooth the hair's cuticle, increase the shine and reduce frizz.
Spread a deep-conditioning hair mask onto your hair once a week. After shampooing your hair, place a small amount of the product in your hand, and then spread the product from the roots of your hair to the tips. Select a product that contains keratin and protein to replace these proteins that were stripped from your hair during the perming process. Allow the mask to remain on your hair for 30 minutes before rinsing.


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It takes more than just police and prison
Consider a simple rational choice model below, in which an individual chooses to offend only if the net gains from offending is greater than the net gains from not offending:
\(\quad\quad\quad\quad\quad\quad\) \((1-p)u_{ s }+pu_{ f }\)>u̲
where \(u_s\) represents his gain when he successfully commits crime, \(u_f\) his loss when he commits crime and receives punishment, and p the probability of punishment. u̲ is his gain when he abstains from crime.
So far, we mainly focused on police and prison as two main crime-control tools. Clearly, they would directly affect individuals' criminal choice by increasing \(u_f\) and \(p\). But it is also clear that the choice to offend or not should depend on other factors, such as the level of expected gain from successful crime (\(u_s\)) or the gain from staying out of crime (u̲).
This week, we will examine how effective crime-control policies may involve more than just law enforcement, judiciary, and correctional systems.
For example, most would agree that providing high-quality public education can potentially reduce problem behaviors of children and adolescents and reduce their subsequent criminal behaviors. Government regulations on alcohol and drug use may have important consequences on crimes such as drug trafficking and DUI. Public health and environmental policies may be also relevant to successful crime control.
Economist Jessica Reyes finds that the U.S. government regulation that eliminated lead from gasoline led to a significant reduction in violent crimes during the 1990s. (Childhood lead exposure is believed to increase children's impulsiveness and aggressiveness.)
Can you think of other government policies that may "indirectly" affect crime?
- Reyes, Jessica Wolpaw. "Environmental Policy as Social Policy? The Impact of Lead Exposure on Crime." The BE Journal of Economic Analysis & Policy 7.1 (2007).
© Songman Kang, Hanyang University


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Brendan Walsh MA is an Archaeologist who was born and raised at the foot of Croagh Patrick. In 1995 he became interested in a story he had heard about since childhood when working as part of an archaeological team on the summit of one of the worlds most famous mountains
Bob of The Reek is a little known story from an area steeped in history which acts as a magnet not alone for Christian pilgrims but for archaeologists, photographers and historians. From a spot looking up at Bob's cave , by a stream just yards from his home, Brendan relates the story he first published as an archaeological paper in 2005.
Podcast: Play in new window | Download
To listen now click play or download to listen later.
Please note that this cave is only accessible via a narrow track in very loose scree and unsupervised visits should not be attempted under any circumstances.


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A Quest
Subject: Marcus Brody, Music by Julian Peters, Lyrics and Vocals by Mike Weber
Jones, Its high time that I join you on a quest!
"Is there anyone here who speaks English? Or maybe even Ancient Greek?"
"Water? No thank you, sir, fish make love in it."
"No thank you, ma'am, I'm a vegetarian."
Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported


text: I'm in! Meow Cat Temporary Tattoo by PAPERSELF £7.50$13.92€8.48$10.02 Favourite Favourite Ask Seller View your favourites PRODUCT DETAILS Cute meow cat temporary tattoo hand drawn by PAPERSELF's illustrator! The perfect gift for any cat lover! Beautifully illustrated design marked with gold detail to give a delicate and intricate effect. Perfect for any occasion.PAPERSELF tattoos mix colour and metallic to create beautifully detailed striking designs on the skin.Each design has multiple ways to apply so get creative with how you apply the tattoos! Cut anyway you want to make beautiful designs on the skin! Each tattoo pack contains 2 sheets. Easy to apply! Just cut and wet with water! They last 2-4 days and are suitable for ages 3+ made from: Designed in London and made in China. Non-toxic, safe and skin friendly. Manufactured in accordance with EU and US safety standards. dimensions: H 18.5cm x W 7cm. product code: 603110 see more see less DELIVERY This product is dispatched to you by PAPERSELF. RETURNS You have 28 days, from receipt of cancellable goods, to notify the seller if you wish to cancel your order or exchange an item. Please note: goods that are personalised, bespoke or made-to-order to your specific requirements, perishable products and personal items sold with a hygiene seal (cosmetics, underwear) in instances where the seal is broken are non-refundable, unless faulty. Read more about our returns policy.Should you choose to return or exchange your order you will need to deliver the item(s) to the UK, where this seller is based. quantity personalise


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About the organization
Rags2Riches is a social enterprise that creates eco-ethical fashion and home accessories out of recycled scrap cloth, organic materials, and indigenous fabrics by working with artisans (mostly women) living in poor communities across the country.
RIIR pieces fuse timeless silhouettes with a selection of traditional and contemporary artisanal techniques. Each piece illustrates the tactile richness of different handmade textures as well as the artful interpretations of the lives and values of the artisans.
Business Category
Retail & Ecommerce
Business Sub-Category
Green products, Jewelry, bags & accessories, Home & décor
Year Founded
What makes it a social enterprise?
Rags2Riches partners with artisans from all over the Philippines, and was created to provide these artisans with fair access to the market and the formal economy, as well as with additional skills-based, financial, and health training so they can maximize their career potential and take steps towards long-term financial and personal well-being.
What is its social cause?Employment development & skills training, Entrepreneurship & local business development, Poverty eradication
Who does it impact?Women, Low-income individuals
Phone Number
+63 2 725 1073
67B Washington St.
San Juan City
Where is Rags2Riches in Philippines
Resources to learn more about Rags2Riches
[Huffington post] What It Takes to Be a Social Entrepreneur - An Interview With Rags2Riches
[Philippine Daily Inquirer] Payatas-based Rags2Riches wins US enterprise award
[Cambio & Co.] Interview With A Trailblazer: How Reese Fernandez-Ruiz Built Rags2Riches Into A Leading Eco-Ethical Brand
Rags2Riches USA


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Mick Lewis has been ruled out of Victoria's Ford Ranger Cup match with Western Australia at Shepparton on Sunday after failing a fitness test on his injured hip muscle. Lewis was unable to complete a training session at full pace at the MCG and his absence will mean the Bushrangers enter the game without their eight contracted fast bowlers, all of whom are out injured.
"I can still feel it a bit," Lewis told AAP. "I want to play but I certainly don't want to rush into anything and risk carrying it for the whole season. There are three more one-dayers and a Pura Cup match scheduled for this month and with so many fast bowlers out injured I want to make sure I get back to full fitness rather than risk putting myself on the sidelines for longer."
The decision means Victoria will keep the same 12-man squad that lost to Queensland in their one-day match on Wednesday including the rookie batsman Aiden Blizzard, who hails from Shepparton.
Western Australia will take 13 men to Victoria after adding the fast bowler Tim Macdonald, who made his first-class debut for the Warriors last week, and Darren Wates to the team that lost by one run to New South Wales at the SCG last Wednesday. Shawn Gillies has been omitted from the squad.
Victoria squad Michael Klinger, Brad Hodge, Cameron White (capt), David Hussey, Rob Quiney, Aiden Blizzard, Andrew McDonald, Jon Moss, Adam Crosthwaite (wk), Grant Lindsay, Clint McKay, Darren Pattinson.
Western Australia squad Luke Ronchi (wk), Chris Rogers, Shaun Marsh, Marcus North (capt), Adam Voges, Luke Pomersbach, Sean Ervine, Brad Hogg, Darren Wates, Brett Dorey, Steve Magoffin, Aaron Heal, Tim Macdonald.


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Helly Hansen Watersport Centre, 15 The Quays, Salford, M50 3SQ
£200 per week plus two offsite trips
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Barry Lessin, MS, is a licensed psychologist who has been serving the Philadelphia region for over 40 years. In his practice, he helps youth and families avoid the harms of drug use and build stronger relationships. He's also co-founder, along with Carol Beyer, of Families for Sensible Drug Policy, an organization dedicated to implementing innovative public health initiatives with the goal of empowering families to increase access to effective substance use disorder treatment and reduce the harmful consequences of oppressive drug policies.
I asked him to explain how we should talk to kids about marijuana, now that it's becoming legal across the country. Here's what he said:
"Good parenting is good parenting, regardless of what state you live in. Experimenting with risky behaviors and challenging authority is part of the reality of normal teen development.
I don't condone cannabis use – abstinence or delayed use is the best choice for young people. In cannabis-friendly states, the challenge is greater for parents because of the culture of greater acceptance and availability.
Safety is the main priority. Be proactive by educating yourself and kids about the law and consequences for underage use in your state. The earlier you have conversations about cannabis, the better. In fact, when kids know that they can ask questions, they're more likely to make good choices and share more openly about other kinds of issues.
Kids need us to 'be real' about drug use by listening to what they have to tell us about their lives and feelings. Listen well and remain positive. This doesn't mean you're agreeing with use, it means you're not judgmental – and judgment always shuts down dialogue."
Brooke Feldman, BSW, is a Certified Youth Recovery Specialist and in long-term recovery from drug problems as a youth. She shared this:
"I see it just like how we talk about tobacco or alcohol use. There are risks for young people to use any substance with a still developing brain. Through education and offering activities and young people enjoy, we can support young people to avoid using any kind of substance that can impair their brain development."
Education, open dialogue, and parents really listening to their kids rather than preaching or judging are the keys to keeping kids safe in a world that is rapidly changing.
Additional Reading: Voices From Both Sides of the Medical Marijuana Debate
Image Source: iStock


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Model trains in O scale with strikingly realistic landscape
This is a very beautiful model train layout with marshalling yard and goods station located in a strikingly realistic landscape. When Pilentum visited a model railway exhibition for model trains in O scale in Germany, there were two modular model train layouts that were assembled to one big model railroad layout. The model railway is operated by two model railway clubs.


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Dear Members & Guests,
We are excited to announce that the course is currently open for play! Various measures have been implemented to ensure a safe and healthy environment.
To book a tee time, or if you have any questions, please call the pro shop at 613-283-5318. Tee times can also be booked online through Visual Golf by clicking here.
We hope to see you soon!
Yours truly,
Rolling Greens Management


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Capital Advocates are proven strategic communication experts valuing a collaborative team approach to drive meaningful business development, organizational change management & policy outcomes with our client partners.
Strategic communication to your key audiences is essential for business development and improving organizational readiness to capitalize on opportunities or overcome challenges. Defining the end goal and working back from it to educate, motivate and activate key stakeholders is key.
Capital Advocates helps business development by identifying the key areas where change is needed. Do you need to support a shift in operations or implement a new technology? We create effective strategic communication plans aligned with key leadership, management and employee stakeholders to convey the benefits of the intended organizational change.
Capital Advocates and its network of highly skilled professionals are experts in helping our clients drive new business development and productivity through strategic communication planning.
Where needed, Capital Advocates' strategic communication planning aligns your strengths and needs with influential government sector decision-makers and public opinion leaders. Our network of experts includes top level state and federal government relations professionals to support this communication.


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Party sources within the United National Party state that the appointment of Deputy Leader may well take longer than expected.
Although speculation was rife that Former Deputy Leader Sajith Premadasa would be appointed to the post during the next party working committee meeting, this decision is expected to be delayed.
Moreover a recent statement made by parliamentarian Sajith Premadasa during the party member's promotion campaign has been scrutinised by senior party figures, which in turn has been attributed to delays in a final decision being formulated.
Meanwhile discussions are also under way to decide if Rukman Senanayeke should be appointed the UNP's next Deputy Leader.


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Head to the end of this post right now if you dig Hatebreed, Killswitch Engage, Sepultura, or all three of these bands.
There's video footage capturing Hatebreed's cover of Sepultura's "Refuse/Resist," complete with Sepultura's guitarist Andreas Kisser.
The performance happened last night at the Monsters Of Rock festival in Sao Paulo, Brazil.
In the video, the Sepultura cover occurs around 27 minutes in.
Also note that Hatebreed, for the entire set, employed the handy bass-slapping prowess of Killswitch Engage's Mike D'Antonio.
Mike, an all-around rad dude, filled in on bass as Hatebreed's Chris Beattie continues to recover from broken bones.
If you enjoyed this post, please consider leaving a comment or subscribing to the RSS feed to have future articles delivered to your feed reader.


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Forever21 Cream Trousers (Similar Here, Here & Here) & Striped Sweater (Red Version) // Gojane.com Heels (Similar Here & Here) // Thrifted Bracelet
So I'm back in Ireland again and I guess, back to reality. I do miss New York (it's definitely starting to hit me today), but I must admit that it's also really nice to be home and to see everyone again. There are some very busy weeks ahead and I'm really excited to get working on some great projects. Like my post last week, these photos were also shot in the stunning Battery Park by Emily Malan. Both this striped sweater and slouchy cream trousers are from Forever21, a store I was so impressed by all Summer. The quality and on-trend pieces had me in the shop a couple of times every week!
Have a great week everyone!
Stylishly Yours,
Erika x


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The goal for this project was simple: receive a push notification whenever someone presses my doorbell. This was made possible (cheaply) by using one of my favorite products from Adafruit: the HUZZAH ESP8266 Breakout Board. This $10 microprocessor has built-in WiFi capabilities, so it's perfect for little IoT projects like this. This project could be built a number of different ways, but my approach aims to be cheap and easy to install.
Parts Required
- Adafruit HUZZAH ESP8266 Breakout
- TIP120 or similar transistor
- Breadboard
- 1K resistor
- Diode
- FTDI / USB Cable
- Existing wired doorbell
- 12V AC/DC adapter, ~500ma (from an old router or something)
- 5V USB charger
- Assorted wire / jumpers
Circuit Setup
The circuit is very simple. All we need to do is power the HUZZAH, hook up the inputs and outputs, and control the doorbell's solenoid using a transistor. Normally, doorbells operate on 12-20 volts AC. However, controlling AC current is potentially more complicated, dangerous, and expensive. Most doorbells also function on 12V DC, so that's the route I took. For the short intervals in which it will operate this should not be a problem (although I'd love to hear any criticisms).
In order to receive commands over the internet and send text messages, two services are needed:
- Twillio is a cloud messaging service, which offers an API to send text messages. After signing up, it's easy to create a phone number for sending messages.
- Temboo is an IoT hub that can interact with many other services, including Twillio. Each interaction is organized into a "Choreo" which you can save and call from code using their software kit. Creating a Choreo for Twillio gives you a key for activating the task.
For anyone new to Arduino, I suggest reading Adafruit's Introduction to the HUZZAH. Once you have figured out how to make it blink, just copy and paste the following gist into the Arduino IDE and replace all the #define values with the actual values from the previous step.
#include <SPI.h>
#include <ESP8266WiFi.h>
#include <Temboo.h>
#define TEMBOO_ACCOUNT "YOUR_TEMBOO_ACCOUNT_NAME"
#define TEMBOO_APP_KEY_NAME "YOUR_TEMBOO_APP_KEY_NAME"
#define TEMBOO_APP_KEY "YOUR_TEMBOO_APP_KEY"
#define TEMBOO_CHOREO_NAME "YOUR_CHOREO_PROFILE_NAME"
#define WIFI_SSID "YOUR_WIFI_SSID"
#define WPA_PASSWORD "YOUR_WIFI_PASSWORD"
WiFiClient client;
int last = -1;
int inputPin = 2;
int flashPin = 0;
int outputPin = 4;
// prototypes
void sendSMS();
void flash(int times);
void setup() {
// Init pins
pinMode(inputPin, INPUT);
pinMode(outputPin, OUTPUT);
pinMode(flashPin, OUTPUT);
// Init serial output
// Init Wifi
int wifiStatus = WL_IDLE_STATUS;
while(wifiStatus != WL_CONNECTED) {
wifiStatus = WiFi.begin(WIFI_SSID, WPA_PASSWORD);
if (wifiStatus == WL_CONNECTED) {
} else {
Serial.println("Setup complete.\n");
void loop() {
int value = digitalRead(inputPin);
if (value != last) {
last = value;
if (value == LOW) {
digitalWrite(outputPin, HIGH);
digitalWrite(outputPin, LOW);
} else {
digitalWrite(outputPin, LOW);
void runSendSMS() {
TembooChoreo SendSMSChoreo(client);
// Set Temboo account credentials
// Set profile to use for execution
// Identify the Choreo to run
// Run the Choreo
unsigned int returnCode = SendSMSChoreo.run();
// Read and print the error message
while (SendSMSChoreo.available()) {
char c = SendSMSChoreo.read();
void flash(int times) {
while(times-- > 0) {
digitalWrite(flashPin, HIGH);
digitalWrite(flashPin, LOW);
I highly recommend getting everything working at your workstation before installing. You can simulate a button press by grounding the input pin and test the circuit with a multimeter. The meter should read 12V very briefly off the transistor and you should receive a text message!
If you're feeling creative, you could easily modify the code to ring the bell using a different rhythm.
Warning: The following steps involve potentially dangerous electrical work- if you don't know what you're doing, just stop.
First, shut off the power to your doorbell. Test the doorbell before and after and take all other necessary precautions to ensure the power is off.
Next, locate your existing doorbell transformer (usually in your basement) and disconnect the wires from it. If you're lucky, there will be two sets of wires - one for the push button and one for the solenoid. In a normal installation, the button closes the circuit and activates the solenoid to ring the bell. We are going to change it so the button is an input for the Arduino, which will then programmatically control the solenoid using the transistor circuit and external power supply.
Lastly, mount the board somewhere safe, connect the wires as show in the schematic and plug in the power supplies.
With the power back on, you should get a satisfying ding-dong, follow shortly by a text message.


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Arborvitae - Emerald Green (Smaragd)
Best Planted in USDA Hardiness Zone: 3-8.
Plant Quick Guide
Growing Zones:
Mature Height:
12-14 ft
Mature Width:
3-4 ft
Full (6-8 hours)
3-4 ft
Growth Rate:
- Description
- Shipping
- Planting
- Care
The Emerald Green Thuja is a very popular plant for hedges and screens, especially in colder climates. It can also make a good foundation plant and is sometimes planted singly as a landscape specimen plant. Occasionally, this plant is pruned to form spiral topiaries. While other members of the T. occidentalis species can be towering specimens as much as 60 feet tall, 'Emerald Green' is a semi-dwarf cultivar that has a narrow pyramid shape. The foliage consists of flat sprays of glossy bright green. The tree has urn-shaped cones about 1/2 inch long that turn reddish brown in fall. Most specimens are 7 to 15 feet in height, occasionally reaching 20 feet. It reaches a maturity size of 12 to 14 feet tall, with a spread of 3 to 4 feet. USDA Hardiness Zones: Zone 3, Zone 4, Zone 5, Zone 6, Zone 7, Zone 8.
Orders are typically shipped within 5-7 business days from the date of your order. You will receive a tracking email upon shipment of your Plant Me Green purchase. Delivery time cannot be guaranteed. Shipping and handling charges are calculated based on the tables below. Please note West Coast states ship only on Monday due to transit time and it will include a $10 shipping fee regardless of whether an order is over $100 due to shipping carrier costs.
Most Plant Me Green trees can be shipped and planted any time of year, unless the variety is specified as only seasonal delivery (such as bare root trees). Our shipping schedule is Monday, Tuesday, and Wednesday. This is to ensure our trees do not stay in a box longer than necessary and arrive to you as healthy as possible. If a package needs to arrive prior to a specific date, or at a more convenient time for you, please notate that upon placement of your order. On some occasions, severe weather and other unusual issues can delay shipping and delivery of your Plant Me Green package. Holiday shipping schedules are set by the carriers.
First, decide on a planting location. Consider carefully what kind of sun, soil, and growing-space your tree or shrub will need. Once you've located the perfect spot, the hole you are digging must be at least double the width and as deep as the root system you are planting. The top of the root system should be level with the ground. Before placing the tree or shrub in the hole, use your hands to gently break up the root system. Once the tree is in place, backfill the hole with native soil and any leftover potting material. Pack down the soil to eliminate any air pockets. When finished, water thoroughly. To insure your plants a successful growth rate and productive life, plant your seedlings per the instructions included in your PlantMeGreen package.
Plant your Thuja in an area with well-drained soil and where it will receive about six hours of direct sunlight each day. Water regularly after planting, making sure to give the tree a deep watering. Try running a slow hose over the roots for an hour or two to accomplish this. While you should fertilize your Green Giant about three times a year, it needs little pruning. Simply remove any dead limbs.


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Black Lives Matter (Sermon)
KEY TEXTS // "The same law shall apply to him that is a native and to the stranger who sojourns among you" [Ex. 12:49, MEV]. "You shall do no unrighteousness [injustice] in a court. You shall not be partial to the poor, nor honor the person who is great, but in righteousness you shall judge your neighbor" [Lev. 19:15]. "Does God pervert judgment? Or does the Almighty pervert justice?" [Job 8:3]. "Therefore the law is powerless, and justice never goes forth. For the wicked surround the righteous; therefore injustice proceeds" [Hab. 1:4]. PRAYER // Our Father and God: we ask and pray that you would equip your Church to advance biblical, social justice in the land. We lament the tragedies of Ahmaud Arbery, Breonna Taylor, and George Floyd—to name only but three recent cases of injustice. There are countless, and we find


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Boys' Clip-On Bow Ties - Prints
Because the misters like to dress up, too! Our collection of assorted colors and prints make Olive + Peony clip-on bow ties the perfect accessory for little man for family pictures and dress-up special occasions, or to make a coordinating sibling set with sis.
Our Lucky Lad Green Plaid pairs with our Lucky Lass Skirt and Scattered Shamrocks Ruffle Tee for St. Patty's Day. The orange dotted Pumpkin Pie matches our Pumpkin Pie Dress, and the Gray/Ivory Check coordinates with our Hovering Hummingbird Sundress and Sweet as Nectar Romper. Other options include Black Check, Baby Blue Dottie, Cardinal Bird, and a White Mini Dino print.
Need a tie in a color or size not pictured here? E-mail us at email@example.com and perhaps we can make you a custom!
Hint: These small bow ties can also double as girls' hair bows!
Flat Lay Measurements:
1 - Length
2 – Width
S - toddler/little boy
3 ¾"
Content: 100% cotton, exclusive of decoration.
Care: Spot clean only; do not launder.
Made in St. Louis, Missouri, USA of imported materials.
*Shipping note - ordering just bow ties today? Use the code BOWTIESONLY at checkout for free shipping on your bow tie order. Code not valid on purchase of any other merchandise or if other items are also in your cart; if code is applied to other merchandise besides bow ties, the order will be cancelled and will have to be resubmitted to apply shipping.


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Bortezomib in Treating Patients With Waldenstrom's Macroglobulinemia
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT00045695
Recruitment Status : Completed
First Posted : January 27, 2003
Last Update Posted : May 17, 2013
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
RATIONALE: Bortezomib may stop the growth of cancer by blocking the enzymes necessary for tumor cell growth.
PURPOSE: Phase II trial to study the effectiveness of bortezomib in treating patients who have untreated or relapsed Waldenstrom's macroglobulinemia.
|Condition or disease
|Drug: bortezomib
|Phase 2
- Determine the efficacy of bortezomib, in terms of response rate, in patients with previously untreated or relapsed Waldenstrom's macroglobulinemia.
- Determine the toxicity of this drug in these patients.
- Determine the time to progression, stable disease duration, and response duration in patients treated with this drug.
OUTLINE: This is a multicenter study.
Patients receive bortezomib IV over 3-5 seconds on days 1, 4, 8, and 11. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.
Patients are followed at 4 weeks. Patients with complete or partial response or stable disease are followed every 3 months thereafter.
PROJECTED ACCRUAL: A total of 15-25 patients will be accrued for this study within 1.5-2 years.
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|27 participants
|Intervention Model:
|Single Group Assignment
|None (Open Label)
|Primary Purpose:
|Official Title:
|A Phase II Study Of PS-341 (NSC 681239) In Patients With Untreated Or Relapsed Waldenstrom's Macroglobulinemia
|Study Start Date :
|August 2002
|Actual Primary Completion Date :
|March 2006
|Actual Study Completion Date :
|December 2009
- Drug: bortezomib
PS-341 bolus intravenous injection twice weekly* for 2 out of every 3 weeks
- Response rate [ Time Frame: 4 years ]To assess the efficacy (response rate) of PS-341 given as a bolus intravenous injection twice weekly for two out of every 3 weeks in the treatment of a population of patients with previously untreated or relapsed Waldenström's Macroglobulinemia
- Toxicity [ Time Frame: 4 years ]To assess the toxicity of PS-341 in patients with Waldenström's Macroglobulinemia as well as time to progression, stable disease duration and, if responses are observed, response duration.
- Cytogenetics and genome profiling [ Time Frame: 4 years ]To assess bone marrow and peripheral blood for cytogenetics and genome profiling by microarray in patients with Waldenstrom's macroglobulinemia.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years and older (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Diagnosis of Waldenstrom's macroglobulinemia confirmed by immunofixation or immunoelectrophoresis
- Newly diagnosed or untreated with IgM ≥ 20 g/L OR
- Previously treated with IgM ≥ 5 g/L
- Non-refractory, defined as no disease progression during prior therapy or within 4 weeks of the last dose of most recent prior therapy (12 weeks for rituximab)
Must have 1 or more of the following:
- Symptomatic lymphadenopathy
- Hepatomegaly and/or splenomegaly
- Anemia (i.e., hemoglobin < 11.0 g/dL)
- Hyperviscosity syndrome
- No other lymphoproliferative disease including transformed aggressive lymphoma
- 18 and over
Performance status
Life expectancy
- At least 12 weeks
- See Disease Characteristics
- Absolute granulocyte count ≥ 1,000/mm^3
- Platelet count ≥ 50,000/mm^3
- Bilirubin ≤ 1.5 times upper limit of normal (ULN)
- AST or ALT ≤ 2.5 times ULN
- Creatinine ≤ 1.5 times ULN
- No uncontrolled bacterial, fungal, or viral infection
- No pre-existing sensory or motor neurotoxicity grade 2 or greater
- No other prior malignancy except adequately treated nonmelanoma skin cancer, curatively treated carcinoma in situ of the cervix, or other curatively treated solid tumor for which patient has been disease free for at least 5 years
- No other serious illness or medical condition that would preclude study participation
- No unreasonable geographical limitations
- Not pregnant or nursing
- Negative pregnancy test
- Fertile patients must use effective contraception
Biologic therapy
- See Chemotherapy
- See Disease Characteristics
- At least 12 weeks since prior rituximab (for patients who have progressed)
- At least 24 weeks since prior rituximab (for patients who have not progressed)
- No prior high-dose chemotherapy and stem cell transplantation
- No prior radioactive monoclonal antibodies
- See Disease Characteristics
- See Biologic therapy
- At least 4 weeks since prior chemotherapy (6 weeks for nitrosoureas or mitomycin)
No more than 2 prior chemotherapy regimens
- The same chemotherapy combination given for first-line and second-line therapy is considered 2 regimens
- Single-agent rituximab not considered 1 prior regimen
- No concurrent cytotoxic chemotherapy
Endocrine therapy
- No concurrent corticosteroids
- At least 4 weeks since prior radiotherapy (except for low-dose, non- myelosuppressive radiotherapy) and recovered
- No prior radiotherapy to more than 25% of bone marrow
- At least 4 weeks since prior major surgery
- At least 4 weeks since prior plasmapheresis
- At least 4 weeks since prior investigational anticancer therapy
- No other concurrent investigational anticancer agents or therapies
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00045695
|United States, Illinois
|Hinsdale Hematology Oncology Associates
|Hinsdale, Illinois, United States, 60521
|United States, Pennsylvania
|Abramson Cancer Center at the University of Pennsylvania
|Philadelphia, Pennsylvania, United States, 19104-4283
|Canada, Alberta
|Tom Baker Cancer Centre - Calgary
|Calgary, Alberta, Canada, T2N 4N2
|Cross Cancer Institute
|Edmonton, Alberta, Canada, T6G 1Z2
|Canada, Manitoba
|CancerCare Manitoba
|Winnipeg, Manitoba, Canada, R3E 0V9
|Canada, Nova Scotia
|Nova Scotia Cancer Centre at Queen Elizabeth II Health Sciences Centre
|Halifax, Nova Scotia, Canada, B3H 1V7
|Canada, Ontario
|Margaret and Charles Juravinski Cancer Centre
|Hamilton, Ontario, Canada, L8V 5C2
|Cancer Care Ontario-London Regional Cancer Centre
|London, Ontario, Canada, N6A 4L6
|Toronto Sunnybrook Regional Cancer Centre
|Toronto, Ontario, Canada, M4N 3M5
|Princess Margaret Hospital
|Toronto, Ontario, Canada, M5G 2M9
|Canada, Quebec
|Maisonneuve-Rosemont Hospital
|Montreal, Quebec, Canada, H1T 2M4
|Canada, Saskatchewan
|Saskatoon Cancer Centre
|Saskatoon, Saskatchewan, Canada, S7N 4H4
|Study Chair:
|Christine I. Chen, MD
|Princess Margaret Hospital, Canada
|Responsible Party:
|NCIC Clinical Trials Group
|ClinicalTrials.gov Identifier:
|Other Study ID Numbers:
CDR0000257042 ( Other Identifier: PDQ )
|First Posted:
|January 27, 2003 Key Record Dates
|Last Update Posted:
|May 17, 2013
|Last Verified:
|September 2011
Waldenstrom macroglobulinemia
Waldenstrom Macroglobulinemia
Neoplasms, Plasma Cell
Neoplasms by Histologic Type
Hemostatic Disorders
Vascular Diseases
Cardiovascular Diseases
Blood Protein Disorders
Hematologic Diseases
Hemorrhagic Disorders
Lymphoproliferative Disorders
Lymphatic Diseases
Immunoproliferative Disorders
Immune System Diseases
Antineoplastic Agents


text:
What I love the most about blogging is discovering new authors, especially those overseas who I might otherwise not hear about. So I was delighted when Australian Samantha Wood, author of The Bay of Shadows. responded to my shout out for authors to take part in guest posts for this Crime Fiction month.
"Everybody dies in your books!" she continued.
"Not everybody," I protested. "Just the bad guys."
It did get me thinking about my piece for this blog, though. Especially Sharon's question about why crime fiction/psychological thrillers are so popular. And what attracted me to write in this genre.
It certainly wasn't a conscious decision, rather I think it was an essential element of the storyline, and one which unfolded organically. In The Bay of Shadows my main protagonist, Elena, is faced with a situation that can only be described as kill-or-be-killed and so decides to take whatever measures necessary to ensure her safety and that of her foster child, Daniel. When I started writing I didn't know how the story was going to pan out so I let my characters lead the way – the end result was part romance, part thriller, part crime, which suited the plot and gave me a lot to work with. The other thing that really attracted me to this genre was the question, and the tagline of the novel: how far would you go for love? When people say "I would never do that," I'm always intrigued by that answer. My first thought is: are you sure? Because we are all capable of amazing and terrible things given the right circumstances. As Elena says after a particularly violent encounter with her child's father, "I'll do whatever it takes." And that is the message at the heart of the novel, that love makes us really powerful.
Having said that, it was still really hard to write about the crime elements. They were essential to the story, because it was the only way of conveying the true danger that Elena and Daniel faced, but it was still hard. Describing a woman – or anybody for that matter – being assaulted, even a fictional one, was incredibly difficult. Anyway, in the end, it added so much to the authenticity of the story which, as authors, is what we are all striving to achieve. You write better when you are honest but it still took a few breaks from the computer to get it done!
As for the bad guy?
Well, he gets it in the end, but we all kind of knew that was going to be the case. It is, I think, the main appeal of crime fiction: that good will, for the most part, triumph over evil. Good always wins. It's a super hero concept, but I like it, and I think a lot of readers do too.
How far would you go for love?
In a rambling house in a small Australian beach town, Elena Jameson is recovering from her recent divorce. To her delight, she is given the opportunity to foster a little boy, Daniel, whose mother is dead and whose violent father is in rehab. As Elena and Daniel explore the beautiful bay and wild bushland, they form a profound bond that will change their lives forever.
Then Daniel's father discovers his whereabouts and begins a campaign of terror – not to get his son back, but to prevent Elena giving Daniel a new life.
As the violence escalates, Elena finds that she's willing to do whatever it takes to protect Daniel from the brutality of his past and an uncertain future. Sometimes the only way to get what you want is to pay the price in blood
Amazon UK: http://amzn.to/2pna0ov
Amazon US: https://www.amazon.com/dp/B01NCI60OZ
Kobo: https://www.kobo.com/au/en/ebook/the-bay-of-shadows
Smashwords: https://www.smashwords.com/books/view/687395
iBooks: https://itunes.apple.com/au/book/the-bay-of-shadows/id1183502249
Samantha Wood was born in Victoria in 1971. Her first book, the memoir, Culua: My Other Life in Mexico was published in 2003 after extended visits to Mexico, and was essentially a love letter to her mother's country.
Samantha graduated from Monash University in 2005 with a Master's degree in Translation Studies (Spanish) focusing on the translations of Gabriel Garcia Marquez's little-known children's stories where angels crash landed in chicken coops and the world's handsomest man washed ashore. It was this love of the magic of language and words that inspired the story for her first novel, The Bay of Shadows.
In 2007, she joined Ai-Media, a world-leading broadcast captioning service that provides access for the Deaf and hard of hearing. She lives in Melbourne, Australia.
Website: http://www.samanthawoodauthor.com
Facebook: Samantha Wood author
Instagram: samanthawoodauthor


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Find out more about the amazing Pattaya Orphanage and what services and care they offer orphaned children throughout Pattaya and Thailand.
This amazing place is certainly not what you would class as a tourist attraction, and it probably doesn't even get recognition from the vast majority of tourists who visit Pattaya. For certain caring individuals however the Pattaya Orphanage can be an extremely life changing experience. This home for long abandoned children is a place that is filled with hopes and dreams for the future of Pattaya and Thailand.
The Orphanage has a very rich and detailed history. In 1972 the Rev. Fr. Raymond Allyn Brennan opened the door of the church that he was serving at to find a newborn child laid on the steps, abandoned by its mother. In an effort to help the child, he took it in and helped foster its care for the time being. Quickly, word spread of what Fr. Raymond had done and more children were being left at the church that he was working at.
Seeing a need for some type of place where these children could be cared for Fr. Raymond met with an American serviceman to help deal with the overwhelming issue of orphaned children. The majority of the children that were being orphaned were those of American military members who were serving in the Vietnam War.
Eventually a building was built and after many years it became known as the Pattaya Orphanage, this remarkable place officially opened its doors in 1982 after gaining its license. It now takes in an average of 160 children that range in ages from newborn infants all the way up to children that are aged around 15 or 16. There is no child that is denied entrance or acceptance into this Orphanage.
In 1999, the Orphanage in Pattaya decided to extend its doors to include a location known as the Sotpattana. Sotpattana Pattaya as it is officially known, is a building devoted to the learning and education of children that are deaf or mute. It is a fully developed audio learning center that helps ensure that every deaf child has a right to an education and a way to learn and communicate. The children that attend this Sotpattana center do not have to be orphaned children, even though the location is run by the Orphanage trust.
Funding for the Pattaya Orphanage is partly sponsored by the government, however a large majority of the funding comes from trusts that have been created all over the world. These trusts allow people to donate money to help develop the many buildings that the Orphanage in Pattaya has, and also to help with the costs of food, living expenses and other educational costs that are incurred by the Pattaya Orphanage.
Even after 36 years of being in existence the Pattaya Orphanage Trust still holds true to its original goals and values that it started out with. It is established with the idea of helping orphaned and abandoned children and giving them food, shelter, education and a chance for a loving family. The Orphanage also offers children the chance to engage in activities that normal children would engage in such as educational classes and sports teams. One of the major benefits that the Orphanage in Pattaya has is that it can work with families in Thailand and around the world that wish to adopt children that are staying at the Orphanage.
If you wish to visit the Orphanage here are the contact details;
Address: 384 Moo 6, Sukhumvit Highway Km.144, Banglamung, Chonburi 20150, Thailand.
Tel: +66 (0) 3842 3468, (0) 3841 6426
Fax: +66 (0) 3841 6425, (0) 3871 6204
Email: email@example.com
Or find the exact location on Google maps by clicking the link below.
Even if you don't get a chance to visit or see the Orphanage in Pattaya it is just an amazing feeling that one has walking by a center that is doing so much good for children who would otherwise have lost hope or been abandoned long ago.
[Go from this Pattaya Orphanage page back to the home page]
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To find the best deals on your Pattaya Hotels, and get a full list of all the Hotels in Pattaya click on the link above, this trusted hotel booking service will save you money on your hotel costs.


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Fires in Mato Grosso, Brazil12.9S 54.1W
Plumes of smoke can be seen from fires in the state of Mato Grosso, in western Brazil. The two main fires, best observed in the full image, can be seen in the lower left and upper right quadrants, releasing smoke westward. Between the two fires is a tract of heavily forested land through which the Ronuro River flows.


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On October 18, 2014, nearly 200 women from diverse communities across Chicago came together at the end of a two month process to forge, through discussion and debate, the first "Chicago Women's Agenda." Some issues* — like equal pay and reproductive rights — are long time challenges faced by previous generations of women. Others reflect more recent concerns – about Democracy, protection of public assets, gun violence. Together these issues represent the thoughts and desires of women on which we intend to act and on which we will judge our would-be elected leaders and their policies.
*All agenda items are of utmost value. They are numbered for clarity and ease of reference.
The Chicago Women's Agenda
What Chicago Women Want For Women Everywhere
- Full Reproductive Rights: Ensure full, affordable access to health services, including contraception and abortion, as well as the pre-natal and family health care services, paid sick leave, and other family-friendly policies that make real choice possible.
The ability to control if and when to become pregnant is central to a woman's ability to control all other aspects of her life – her education, employment, the very life she can lead. That is why the core issues of reproductive justice are full access to contraception and abortion. Yet full reproductive justice also requires that the choice to have children be made knowing that they can be raised in safe and healthy environments, with economic and housing security
Older women have particular needs as well. As women typically take more time off to care for family members, they often face great challenges as they age since their lifetime earnings, pensions, and retirement savings are likely to be less than those realized by men.
Potential Actions:
- Protect full access to contraception and abortion in Illinois
- Pass the Family and Medical Insurance Leave Act
- Pass the Family Care Act
- Protect Social Security and pass the Caregivers Act
- Boycott businesses that deny women full health care and insurance
- Economic Security: Raise the minimum wage to $15 per hour for a full week of work, and ensure equal pay for equal work.
A great many Chicago-area women are responsible for their own economic security and that of their families. According to the National Partnership for Women and Families, 476,550 households in the metro area are headed by women. About 29 percent of those households, or 138,676, have incomes below the poverty level. With 66 percent of low-wage jobs held by women, and women earning 80 cents for every dollar earned by a man, only by ensuring equal pay for equal work, raising the minimum wage, and guaranteeing a 35 – 40 hour work week will women be assured of a "sustainable family income".
Potential Actions
- Pass minimum wage and minimum hour legislation at the City, County, State and Federal levels, preferably at $15 per hour
- Pass federal legislation calling for equal pay for equal work
- Pass the Federal Paycheck Fairness Act to protect and empower women
- Support legislation and worker efforts to ensure full-time employment with benefits
- Economic Empowerment: Ensure that women have the opportunities they need for economic success, including access to quality, affordable education and training and to capital for entrepreneurial ventures.
Women need access to high quality education from early childhood to college and post graduate training, with a focus on higher paying STEM skills. A two-year degree means an average 38 percent increase in pay; with a four-year degree, a woman earns 88 percent more than with a high school diploma. Increasing financial aid, counseling and career guidance, and support services such as childcare and transportation, will ensure that women receive the education they need and want. Education alone is not enough. While entrepreneurship is perhaps the best route to better pay, even with education and ideas, women are often denied capital. Seven percent, or 183 of 6,517 companies receiving venture capital funding from 2011-2013, had a woman CEO. With 7.8 million women-owned businesses in the United States, only 3 percent of total venture capital dollars, or $1.5 billion out of the total of $50.8 billion invested during 2011-2013, went to companies with a woman CEO.
Potential Actions:
- Ensure STEM programs for girls in all neighborhood and specialized schools
- Reduce the interest rate on student loans to zero percent
- Create funds to help women start and scale businesses to triple job growth.
- Expanded Opportunities for Young Women: Increase access and funding for sports, education, good nutritional choices, and health care, and end objectification, including rape and sex trafficking, that stifles possibilities.
Girls face unique challenges to their health and development that are often overlooked. Despite Title IX, girls, particularly those of color or living in poor communities, do not have equal access to sports and fitness opportunities and face higher rates of obesity and other related health risks, yet less than 4 percent of national funding is directed to girl-specific programs and opportunities.
While much progress has been made, sex stereotypes, parental, educator and peer expectations as well as the dominant culture too often discourage girls from fully realizing their potential.
Potential Actions:
- Ensure that there is parity in City, State and Private funding for after- school and summer programs for young women as well as health education and care
- Encourage girls' leadership in science, sports, and other non-traditional activities
- End stigma and discrimination on the basis of sexual orientation.
- Real Immigration Reform: Pass comprehensive immigration reform legislation that protects women and reunites families.
More than 16 million people live in mixed-status families in the United States, with at least one person an unauthorized immigrant – vulnerable to exploitation and deportations that disrupt families with dire consequences. Recent years have seen a dramatic increase in deportations, with an estimated 204,000 parents of children with U.S. citizenship deported between July 2010 and September 2012 alone. The harm is palpable: from families that suffer the loss of income to the suffering of thousands of children who end up in the public child welfare system; from the under-reporting of domestic violence by women who fear deportation more than their abusers to the children and parents who often miss work or school to avoid encounters with law enforcement and bureaucracies.
Potential Actions
- Provide access to schools, health care, drivers' licenses and bank accounts for all immigrants
- Replicate Illinois' immigrant-friendly policies in other states
- Pass comprehensive Federal immigration reform
- Freedom from Violence: Create real consequences and laws to end the violence against women, particularly young women, that affects every realm of their lives – from harassment on public transportation, sexual assaults in the military, and on campus, to the violence that occurs at home.
Sexual assault and domestic violence are pervasive, seen in recent revelations about sex trafficking, sexual assault on campus and in the military. Domestic violence and date rape are not simply problems, they are crimes and should be treated as such. Girls, in particular, face the challenge of violence; from public harassment to sexual exploitation in the privacy of home, to rape on college campuses, where nearly 1 in 5 young women are sexually assaulted.
Of growing concern is the increase in human trafficking. Over 100,000 children are commercially exploited for sex each year in this country; most of them girls. This will only end with efforts to eliminate demand, prosecute traffickers, and provide services and shelter to victims.
Potential Actions
- Pass the Sexual Assault Bill of Rights for students pending in the Chicago City Council
- Begin anti-violence education in the schools at an early age
- Increase funding for legal advocacy and domestic violence shelters
- Monitor media for 'blame the victim' and voyeuristic coverage
- Prosecute human traffickers and increase services for victims
- Common Sense Gun Control: Enact sensible gun control laws that outlaw assault weapons and make guns of all types less accessible.
Gun violence in schools rivets public attention, and nightly news reports are filled with stories of yet another young person killed. Women in particular are vulnerable to gun violence. As moms, sisters, and daughters, spouses and girlfriends, they suffer first-hand the effects of the more than 11,078 homicides and 19,393 suicides that occur each year. According to the Center for American Policy, from 2001 through 2012 alone, 6,410 women were killed with a gun by a husband or boyfriend. -his is a figure that, according to the Center for American Progress, is "more than the total number of U.S. troops killed in action during the entirety of the Iraq and Afghanistan wars combined"
Potential Actions:
- Pass meaningful gun control legislation at the federal state and level
- Increase funding for mental health services
- Boycott stores (like Target or Walmart) that sell guns
- Criminal Justice Reform: Decriminalize drug laws and reform police, courts and prisons to end brutality, wrongful convictions and sentences that impair lives.
Called the New Jim Crow, today's criminal justice system is filled with youth of color – victims of poverty, racial profiling, and disparate sentencing, and too often of police brutality and wrongful conviction. That the tragedy of such injustices is compounded by laws that make gainful employment, housing and even voting difficult has created whole communities where poverty, prison, and constrained options combine to harm women and families most at-risk.
Potential actions
- Pass legislation to decriminalize minor drug possession
- Press for transparency of police review board records of those involved in shootings or beatings and support reparations for Burge victims
- Restore rights to those who have served time and returned to communities to begin or resume productive lives with real freedom
- Protection of Public Assets: Preserve and protect the public institutions and assets that provide opportunity and well-being for women and their families.
Much of America's social mobility derives from the creation and protection of public assets – schools, parks, health care, roads, etc., from which all benefit. The privatization of schools, and the shuttering and selling off of assets like schools, health clinics, and roads, deprive women and their families of needed assets, robs communities of anchors, and shuts doors on opportunity.
Potential Actions
- Demand public vote referenda before public assets (parks, schools, lakefront, etc.) are converted to private use
- Strengthen the power of landmarks and other preservation entities
- Protect national parks and other parts of the country's patrimony
- Restore mental and other public health care clinics to public stewardship
- Safeguard public schools and keep them public
- Protection of Democracy: Ensure the right to vote, the right to speak and voice unpopular opinions, to gather in public places and to unfettered access to the Internet.
The past decade has not been good for democracy. The draconian rules passed in the wake of 9/11 that restrict public gatherings, criminalize certain relationships, and enable the vast surveillance network of the NSA, threaten both public and private spaces for thought and dissent. At the same time, the U.S. Supreme Court decisions created corporate personhood and 29 states attempted to restrict voting rights. Not since African Americans and women won the right to vote has democracy been so threatened.
The third front of the battle is one of technology. With the advent of the smart phone and digital technology, the Internet can be a great force for more democracy—only if it remains an open and accessible, where all content is considered equal and where access cannot be bought or sold.
Potential Actions:
- Keep Illinois free of special identification requirements and other prohibitive rules, and repeal City, State, and
- Federal laws designed to curb demonstrations
- Protect free speech rights on campuses and in the workplace
- Encourage women of all ages to engage in the digital world
- Protect the Internet from a two-tiered content system
- Overturn Citizens United
11. Livable Conditions: Pass legislation and engage in practices that ensure that the environments in which women and families live are affordable, healthy, and safe, with access to nutritious food.
A safe, affordable home near employment, good schools, transportation, and nutritious food is essential to raising a family. Yet too often women, with their lower wages, are priced out of housing in such locations. Policies are needed to assure fair, affordable housing in a supportive environment, so that low and moderate income residents can live sustainably.Toxic chemicals and pesticides in the air, water and earth (crops) are responsible for a variety of women's health risks. They enter body tissues and breast milk and are passed on to infants. Sustainable development demands recognition and value for the many ways women's lives intersect with environmental realities. The State of Illinois ranks 7th in the country for carbon pollution from power plants which are the state's largest single source of dangerous emissions.
Potential Actions:
- Increase the availability and amount of well-located affordable housing through Federal, State
and local funding
- Create an independent Illinois Environmental Justice Commission
- End Petcoke stockpiling, fracking and Great Lakes oil exploration


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Privacy Policy
This Privacy Policy describes how ConforMIS, Inc. ("ConforMIS") collects, uses and discloses information about Users and their use of the ConforMIS.com and [ConforMIS.Orders.com] sites (each, the "Site"). ConforMIS has a strong commitment to protecting the privacy of Users and to assuring the integrity of the Site. This Privacy Policy has been developed with these goals in mind and will be continuously assessed against new technologies, business practices and Users' changing needs.
1. Information We Collect
Our primary goal in collecting information from Users is to provide a Site with integrity and to enable us to provide you with efficient and professional products and services.
In general, ConforMIS does not collect "personally identifiable information" about you, except when you knowingly provide such information as the result of the use of one or more of the features of the Site. Although you do not have to provide us with any personal information to visit the Site, you may not be able to fully use all the services on the Site if you choose not to provide certain information. If you do choose to give us personally identifiable information through the Site, we will collect and retain that information in accordance with this Privacy Policy.
(a) User Information. To request information concerning our products and services, Users may contact us using our online request form or automated email, where they are required to provide us with User information, including personally identifiable information such as name, entity/practice name, address, telephone number, email and other information. We may also collect other types of non-personal information (information that, by itself, cannot be used to identify or contact you), such as demographic information (your age, gender, income, education, profession, zip code, etc.) and information about your personal interests, which we may associate with personally identifiable information. Furthermore, to [purchase our products or] access certain features available on the Site, Users must register using our online registration form, where they are required to provide us with User information, including personally identifiable information such as name, address, telephone, email and other information. If you purchase products or services from us, or desire access to certain features, you will be assigned a Password to identify you and your account. Finally, our Site may offer message boards, conversation pages, chat rooms, social community environments, profile pages, and other Public Forums (as defined in the Terms of Use governing our Sites (the "Terms of Use")), as well as other features in which you may provide us with User Submissions (as defined in the Terms of Use). If you provide personal information when you use any of these features, that personal information may be publicly posted and otherwise disclosed without limitation as to its use by a third party. Our rules regarding User Submissions are described in the Terms of Use.
(b) Usage Information. We also automatically track certain information about Users based upon their behaviour in the Site. Such information may include the URL that the User just came from, which URL the User next goes to, what browser the User is using, and the User's IP address.
c) Information Not Collected. We will never ask you for personal information such as your social security number, or any banking, credit card or credit history information, and such information should not be submitted to ConforMIS or posted on the Site.
2. Third Party Sites
Users may be redirected from the Site to a third party Site in order to access such third party's information, or to use such third party's online tools [including order and payment processing to complete the payment of any applicable product fees to ConforMIS]. Users may provide that third party with personally identifiable information, or other information which may be requested or collected by such third party, including banking and credit card information. ConforMIS does not have access to that information, and a User's disclosure of such information to a third party is at its own risk and subject to such third party's privacy terms.
3. Our Use of Information
Generally, we use information about our Users to analyze Site usage, to improve our content, products and service offerings and to customise our Site's content, layout, and services to meet our Users' needs. We use information to process User requests, to contact Users regarding their use of, changes to, or new products or services that we offer, and to do internal research on our Users' demographics, interests, and behaviour to better understand and serve our Users. We may use information to market our products and related services, including special offers and promotions. These marketing and promotional materials may be sent to you by postal mail, email or other means. However, the individual or organisation will always be given the opportunity to elect to "opt out" to not to receive further marketing information from us. See Section 8 below for ways to opt out. Finally, we may use your information to complete transactions requested by you (such as your purchase of a product or service offered on our Site), or to send you administrative communications either about your account with us or about features of our Site, including any future changes to this Privacy Policy. Because these do not involve sending you promotional materials, your opt-out option will not apply permitted transactional or administrative uses of your personal information.
4. Our Disclosure of Information
ConforMIS's policies regarding the disclosure of User information are as follows:
We do not sell, rent or loan User information to any third party.
We will obtain permission before disclosing any User information for a purpose not authorised by a User or this Privacy Policy.
We may occasionally aggregate our User information and disclose such information to third parties in aggregate form for a number of business purposes, including running and enhancing the Site. In these situations, we do not disclose any information that could be used to personally identify our Users.
Occasionally, we may disclose User information to third parties we engage to facilitate our services. In such instances, we obligate those third parties to conform to our privacy standards. In addition, our corporate policies require that employees with access to confidential information about our Users may not use or disclose the information except for ConforMIS's business use.
ConforMIS may transfer personal information subject to this Privacy Policy to a purchaser in connection with the sale of all or a portion of its business or assets.
We reserve the right to disclose or report information about our Users in limited circumstances where we believe in good faith that disclosure is required under law, to cooperate with regulators or law enforcement authorities, and to protect the rights, safety and security of ConforMIS, the Site and our Users. Furthermore, we may disclose User information to enforce our Terms of Use, or enforce contest, sweepstakes, promotions, and/or game rules that we may offer on the Site.
5. Security Measures to Safeguard Information
The security and confidentiality of your information is extremely important to us. We have implemented technical, administrative, and physical security measures to protect User information from unauthorised access and improper use. From time to time, we review our security procedures in order to consider appropriate new technology and methods. Please be aware though that, despite our best efforts, no security measures are perfect or impenetrable.
6. Cookies
We use cookies to assist us in securing your transactions and to enhance the performance of the Site. We use a common technique, HTTP-header cookies, to identify one page request from another. The cookies the Site creates do not contain any personal information. They merely allow us to recognise that a page request comes from someone who has already logged on. While your browser may allow you to "reject" cookies, the Site requires that you accept all cookies in order for the features and security mechanisms to function fully. Cookies are stored on a User's hard drive, not on the Site. Cookies are "session cookies", meaning that they are automatically deleted at the end of a session, or are automatically "timed out" after extended inactivity.
7. Security and Browsers
Any time a User enters information on the Site, we encrypt it using Secure Socket Layer (SSL) technology. SSL protects information as it crosses the Internet. To support this technology, Users need an SSL-capable browser, preferably with strong encryption.
8. Opt-Out Options
There are several methods by which you can exercise your opt-out choices to not receive marketing communications from us: (a) during the registration process on our Site; (b) after registration, by logging on our Site, clicking on our "Privacy Policy" links [going to the Site's "Member" section], and following the opt-out directions; or (c) by replying with the subject line "unsubscribe" in an email to email@example.com.
9. Changes to User Information and Transaction Information.
If you are a User and have a concern about your User information, or want to correct, update, or confirm such information, please log in to the Site and view and/or change such information under the Site's ["Member" section].
10. User IDs and Passwords
Your email address, together with your Password, is your private entry key into accessing the premium features on the Site. You should never share your account information or Password with anyone, and you should change your Password periodically on the Site [at the Member link]. If you need to recover your Password, you can also contact us via email at email@example.com . Please include information in the email that will help us identify your account so we can assist you with your request. We will associate that email address and Password with the User information that you provide during registration (that is, your postal address, email address, or any other information that would directly enable us to contact you) and information that we collect during your subsequent transactions such as online orders and your use of the premium services on the Site. In some cases, your account may expire or be terminated under our Terms of Use. If so, you may contact us [at Member Services] at the address in the Contact Us link to update your information and opt-out choices (to the extent that we still retain them).
11. Application of this Policy
This Privacy Policy applies only to personally identifiable information collected on the Site where this Privacy Policy is posted and does not apply to any other information collected by ConforMIS through any other means.
12. Contact Us.
If you have any questions or concerns about this Privacy Policy, please contact us by email at firstname.lastname@example.com or by telephone or postal mail as indicated under Contact Us
13. Amendments.
We may amend this Privacy Policy at any time. If we amend this Privacy Policy to permit material changes in the way we collect, use, and/or share your personal information, we will notify you of such amendment by sending you an email at the last email address that you provided us, and/or by prominently posting notice of such amendment on the Site. Any such amendment will be effective thirty (30) calendar days following either our dispatch of an email notice to you or our posting of notice of the changes on the Site. Please note that, at all times, you are responsible for updating your personal information to provide us your current email address. In the event that the last email address that you have provided us is not valid, or for any other reason is not capable of delivering to you the notice described above, our dispatch of the email containing such notice will nonetheless constitute effective notice of the amendment described in the notice. In any event, an amendment to this Privacy Policy may permit material changes in the way we use and share personal information that you provided us prior to our notification to you of such amendment. If you do not wish to allow such material changes, you must so notify us (in the manner we specify) prior to the effective date of the amendment. If you provide us this notice, we may choose to deactivate your account. Please be advised, however, that, regardless of whether you provide such notice to us, any such amendment to this Privacy Policy will apply to any personal information that you provide us on or after the effective date of such amendment.