text:
Include Blair Hull, founder of Ketchum Trading, among those who are concerned about the consequences of high-frequency trading, about what he calls the "illusion of liquidity" that it substitutes for the real thing, and among those who has definite ideas as to what the authorities might do about it.
Hull is renowned for buffering the Black Monday crash of 1987. He was buying, and thus restoring liquidity at the bottom, the following day (October 20). In 2005, Trader Monthly compiled a list of "the 40 greatest trades of all time," and put Hull's purchases in the MMI pit that October as the 17th greatest.
Hull addressed The Trading Show Chicago 2012 on June 24, 2012 on this topic: "Examining the Revolution – How Technology is Changing the Trading Landscape."
Trading and Computers
After a preliminary discussion of blackjack, Hull moved to the tangled history of technology on the trading floors. He reminded his audience that it wasn't until 1981 that they could actually write a FORTRAN program to access real-time prices. As late as 1985 exchanges still prevented traders from even having computers on the floor. The irony of course is that the old-fashioned "floors" have nearly disappeared by 2012, and exchanges now, in essence, are computers.
He comes in this way to that 1987 crash. On October 19th, fear took over the trading process and "prices moved almost as if there were no buyers." Why? Because the portfolio insurance company, LOR, had unwittingly managed to substitute the illusion of liquidity for its reality. Their computers were programmed in a way that assumed that one could sell futures at any necessary price.
Rubinstein, the "R" in LOR, was a professor at Berkeley, Hull recalled. Soon after the crash, the two men met at a social event and Rubinstein confessed, "I think I caused the crash." He was one of the first to reach that conclusion, and he was right.
Hull, as if to remind us he isn't against technology, also spoke of how during his time on the CBOE board in the late 1980s he was the "least popular member" there, precisely because he pressed to automate trading. He seems still ticked off that his warnings were unheeded, and that ICE stole a march on the Chicagoans there.
Where We Are Today
In bringing his remarks into the 21st century, Hull gives a shout-out to Scott Patterson's book, Dark Pools. This book describes, in Hull's summary, that traders around the country "took the game away from New York," and in the process invented high-frequency trading. Despite its name, HFT isn't really about speed. It is about queue position and ordering, and thus about cancelling.
In the process of taking the game away from New York, these bright and ambitious traders and technologists were making queue position even more important in trading than price. Here Hull moves into a discussion of Reg. NMS. It is "extremely complicated" but one of the provisions is the order protection rule. Reg NMS was "a tremendous gift to HFT," and its unintended consequences led to the creation of both Direct Edge and BATS.
The Flash Crash and Since
From: Blair Hull's presentation, Chicago Trading Show
The graph above shows the flash crash of May 2010. The impressive chasm near the day's end occupies only about ten minutes: four minutes on the way down, six minutes coming back up. If the fall had come at the day's end, if there had been no time for a recovery, there might well have been more serious macro consequences.
The real problem, Hull says, is that again as in 1987 (in a different way of course) traders were working within a market structure that allowed "the illusion of liquidity" to displace the real thing. He cites an authority, because as he says his firm, Ketchum, likes to stay close to the academic literature. The academic authority is Ananth Madhavan, the article "Exchange-Traded Funds, Market Structure and the Flash Crash." Hull quotes Madhavan saying "Our results show the Flash Crash can be linked directly to current market structure."
From: Blair Hull's presentation, Chicago Trading Show
Hull recommended that the authorities do three things: allow a zero spread; designate a minimum order life; charge for cancels.
As his presentation drew to a close, Hull mentioned briefly microwave technology, which will still further quicken the pace of events in trading. See above graph for the scale of the change
His conclusion, though, was that the SEC could make the business of trading more fair and more stable "if they really understood the problems."


text:
Download FAQs
1. Why Restaurant.com?
There are many ways to reward and retain clients, customers and employees, but nothing works quite like a gift. And few gifts have such universal appeal as a Restaurant.com Gift Card or Certificate. With more than 20,000 restaurants nationwide from which to choose, you're sure to satisfy even the choosiest of taste buds. Restaurant.com Gift Certificates bring the joy of a meal well served to every recipient, while positioning your company brand and marketing message top-of-mind for greater impact. So, no matter the goal, Restaurant.com has a solution for you.
From casual to elegant dining and featuring many popular cuisine types, Restaurant.com Gift Certificates offer recipients an enjoyable dining experience at an affordable cost to you. Based in Arlington Heights, Illinois, Restaurant.com has operated since 1999.
2. How many restaurants participate in the Restaurant.com program?
There are over 20,000 restaurants nationwide to choose from. Additionally, there are great online retailers that also accept the gift certificates. Please go to http://Dine.Restaurant.com to see participating restaurants and online retailers.
3. Do gift cards and certificates expire?
Restaurant.com Gift Certificate codes do not expire.
4. What denominations are available?
Restaurant.com Gift Certificates and Cards are available in denominations of $10, $25, $50 and $100.
5. Are there minimum orders?
The minimum order for Restaurant.com Gift Certificates and non-customized Gift Cards is $200 (not including shipping and handling). Co-branded gift cards and gift certificates with your company logo or other image require a minimum order of 1,000 units. For co-branding of less than 1,000 units, there is a $250 service fee.
6. What forms of payment are accepted?
We accept Visa, MasterCard, American Express and Discover Card. Corporate checks are also accepted.
7. What is your shipping policy?
All gift certificates and cards are shipped via FedEx Ground. Expedited delivery is available for an additional charge. Electronic gift certificates are sent via email to the specified email address on the order form.
8. Are there any special terms for using Restaurant.com Gift Certificates?
The main requirement associated with Restaurant Gift Certificates and Merchant Certificates is that only one (1) may be used per restaurant visit or transaction and may include a minimum purchase requirement. The end-user must be sure to read all specific restrictions for each restaurant or online merchant, as well as our standard terms and conditions.
Get Started Now

subset: commoncrawl


text:
A guest blog post by Andreas Jakl, Tieto
Especially in enterprise and industry scenarios, both NFC and Windows are equally important. While Windows 8 already started exploring NFC features, Microsoft went a lot further with Windows 10. The new operating system version finally enables easy development of sophisticated NFC apps with standard platform APIs, to create apps that scale from mobile and embedded devices to desktop PCs and terminals.
Here is a brief overview of the three most important new NFC features in Windows 10:
Smart Card Access
Windows (Phone) 8 only allows NFC interactions on the open content layer (NDEF standard). Even though the powerful open source NFC / NDEF Library adds a lot of important content handlers, many commercial scenarios like transportation tickets require lower-level communications with the NFC card.
Windows 10 includes an API for smart card access that also allows requesting the NFC communication channel. Once the device detects a smart card, it's only a simple API call to query the basic smart card characteristics. In most cases, the app will then proceed to communicate with the NFC smart card by sending commands and reading the smart card's responses (through APDUs). In particular, for sending custom commands and for getting really down to the raw communication interface, Windows 10 even supports the Transparent Exchange mode.
Host Card Emulation
Earlier versions of Windows Phone already allowed using the secure element of a SIM card. However, "simulating" smart cards with apps has proven to be an approach that is a lot more flexible. Windows 10 Mobile now added Host Card Emulation (HCE) support to enable these new scenarios.
Essentially, the user taps an NFC terminal with the phone – e.g., in a retail store to initiate the payment. The external terminal then attempts to communicate with the corresponding app on the user's phone. If the app is not already running, a background thread of the app handles the communication and (if needed) launches the visible app user interface. More details on the architecture of Host Card Emulation in Windows 10 along with some code samples are available on the Microsoft NFC Team Blog.
NFC Simulator
Maybe the simplest of the three new features, but still tremendously helpful for app development and testing, is the new NFC simulator that's built into the Windows 10 emulator. It allows testing the standard proximity APIs for NFC / NDEF tag access, Smart Card Reading as well as Host Card Emulation – all without the need for real test devices or tags. More details are available in the Microsoft Documentation.
Windows 10 now provides a solid base for all NFC scenarios. It offers more opportunities for app developers, especially in enterprise and industry segments. Services can now integrate with popular NFC infrastructures like smart cards, payment services or ticketing and transportation scenarios.
To get a more detailed walkthrough of new Windows 10 NFC features, watch the recorded session on YouTube: Which new scenarios are enabled by Windows 10 for NFC, Bluetooth LE and Beacons. For developers, a lot of the new NFC features are demonstrated in Microsoft's Windows 10 NFC sample, which can be downloaded from GitHub. Also available on GitHub: the open source NDEF Library with recently added Windows 10 support.
About our guest blogger:
Andreas Jakl (@andijakl) is working as a Mobility Expert at Tieto, to bring the partner's vision for mobile apps to life. In addition, he is organizing the Mobile Developer After-Work event series together with the mobility.builders community, where expert developers share their knowledge. As Microsoft MVP (Most Valuable Professional) for Windows Development, he has created open source NFC and Bluetooth Beacon libraries for Windows app developers.


text:
Gear Coupling Troubleshooting and Reliability
Gear couplings have been around for a long time. And yet there are still frequent equipment failures due to improper selection, use, and maintenance of couplings.
Keep in mind that a coupling problem can manifest itself in subtle ways. A broken coupling is pretty obvious. However, you could see symptoms such as:
– Increased vibration readings in the equipment
– Overheating of shaft bearings
– Unusual resonances in your vibration data
– Overload and overheating of motors
The Equifactor® module of the TapRooT® VI software service has some great troubleshooting tables, one of which is focused on gear couplings. Once you determine that you have a coupling issue, you can look up the symptoms you are seeing and determine what could be causing that symptom.
I also found a nice article describing problems you might have with a coupling, and how to maintain the reliable operation of a gear coupling. Take a look and let me know what you think.


text:
Press releases
Nordstjernan accepts bid for Norwegian listed furniture Group Ekornes
The investment company Nordstjernan AB ("Nordstjernan") has through pre-acceptance confirmed that the company is divesting its holding in the Norwegian listed furniture Group Ekornes ASA ("Ekornes"). This is provided that the transaction entered into today between Ekornes and a Chinese consortium, headed by the Chinese furniture company Qumei Home Furnishings Group Co. Ltd. ("Qumei"), is completed.
Nordstjernan owns 6,359,652 shares in Ekornes, corresponding to 17.2 percent of capital and voting rights in the company. Ekornes was established in 1934 and Nordstjernan has been the largest shareholder in Ekornes since 2008.
"Ekornes is a first-rate company, and owns one of the world's strongest furniture brands – Stressless®. The company's management and Board of Directors has been highly successful in recent years, rationalizing costs and acquiring the Southeast Asia-based furniture company IMG. In the next phase, I believe Qumei can create new growth opportunities and represents a good option as a new industrial owner of the company. I also consider the bid of NOK 139 per share attractive. If the bid is accepted, this means, together with the dividend paid of NOK 31, returns over the past 24 months have totaled 85 percent excluding the reinvestment of dividends. Because we consider the bid attractive, both for Ekornes and its shareholders, Nordstjernan has decided to support the pre-acceptance," says Tomas Billing, CEO of Nordstjernan.
Tomas Billing
President and CEO
Nordstjernan AB
Questions will be answered by:
Tomas Billing, CEO of Nordstjernan
Telephone: +46 8 788 50 18
E-mail: firstname.lastname@example.com
Nordstjernan AB is a family-controlled investment company whose business concept is to be an active owner that creates long-term and positive value growth. More information about Nordstjernan can be found on www.nordstjernan.se.


text:
VALUES - How we do it?
D uty– do the right thing unconditionally.
O penness– promote agility, flexibilityand consistency.
K nowledge– create with curiosity, experienceand advanced tools.
I nnovation– do it our way!
N etwork– grow our family of clients and focus on their needs.
G roup– cultivate the team work culture


text:
Report of the Local Electoral Area Boundary Committee
Report of the Local Electoral Area Boundary Committee
Mr. Phil Hogan T.D., Minister for the Environment, Community and Local Government announced today (30 May 2013) the publication of the Report of the Local Electoral Area Boundary Committee established by him in November 2012 to review and make recommendations on local electoral areas.
The Minister in publishing the Report announced that he has accepted in full the recommendations in the Report and that he will be making the necessary local electoral area orders to give effect to these in due course. The local electoral areas specified in these orders, and the number of members to be elected for each electoral area, will apply at the 2014 local elections. The Minister thanked the Committee for carrying out its important work in a timely and efficient manner.
The Minister said "the completion of this report is an important next step in the Government's programme for local government reform. The review had a specific goal of improving balance and consistency in representational ratios in local government, while taking particular account of factors such as the location of towns in the new municipal governance arrangements provided for in the Action Programme for Effective Local Government. The terms of reference for the review provided for minimum levels of representation in lower population counties and cities."
The Committee has made recommendations on the division of each Council area, other than Cork City, into local electoral areas. These are named, detailed and mapped in the report. The Committee has also made recommendations on the number of members of each council to be assigned to each local electoral area.
Arising from the recommendations in the report a total of 949 councillors will be elected at the 2014 elections, in 137 local electoral areas, for 31 local authorities. This is a significant reduction from the current 1,627 councillors (of which approximately 200 are both town and county councillors).
"Many will focus on the reduction in the number of council seats from 1,627 to 949 and the number of local authorities from 114 to 31. However, beyond these reductions is the development of a far more integrated approach between county and municipal government to better serve the needs of all citizens. This radical structural reform will provide a sound platform for the wider development and strengthening of the local government system in the future," said Minister Hogan.
The current number of councillors in local authorities was set in the distant past. There have been huge changes in population in recent decades, which have resulted in great disparities in the ratios of councillors to population as between different counties.
Whereas previous local electoral area reviews left the totals in each local authority unchanged, the current review involved a fundamental reform of the system to take into account the population changes and representational disparities.
In carrying out its work, the Committee was also required to have regard to the Action Programme for Effective Local Government and in particular the proposals for a new municipal district structure for local government in counties outside Dublin. The recommended local electoral areas will form the basis for configuration of the new municipal districts. The Committee also had regard to the decision of Government to merge the councils of Limerick City and Limerick County, North Tipperary and South Tipperary and Waterford City and Waterford County.
The Action Programme for Effective Local Government recognised the need for a certain minimum critical mass to enable a council to operate effectively and accordingly, the terms of reference for the boundary committee provided for a minimum of 18 seats per council, so that the smaller rural authorities in particular have a much more favourable level of representation than would have been the case if population ratios were being uniformly applied.
Absolute equality is not feasible. If the overall average ratio of 1:4,830 was applied to the 4 Dublin local authorities for example, this would result in an increase in the total number of councillors to 264, more than double the current total, which would not be sustainable in the context of reform. Accordingly, the number of seats in each of the Dublin counties has been capped at 40 and the membership of Dublin City Council has been increased to just 63. This is considered appropriate in the context of rebalancing the distribution of council seats nationally.
The Report is available online at www.boundarycommittee.ie and at www.environ.ie and will be available next week from the Government Publications Sale Office, tel. 01 6476834.
Municipal districts
The recommendations on local electoral areas will provide the basis for the configuration of the municipal districts to be established in counties outside Dublin in accordance with Putting People First: Action Programme for Effective Local Government. Generally, each municipal district will consist of a single electoral area. However in some particular circumstances, for example for reasons such as geographic coherence, population, or other factors related to the configuration of municipal districts such as the definition of 'metropolitan' municipal districts within the unified authorities in Limerick and Waterford, a district may comprise more than one local electoral area.
The Local Government Bill 2013 being prepared will provide for a range of reforms across local government including structures i.e. mergers, sub-county and regional reconfiguration. It will include specific provision for the determination of municipal districts by the Minister by order.
The tier of town local government as we know it will no longer exist. These existing sub-county structures will be replaced by a new, coherent model of municipal governance which will address current weaknesses and anomalies in the existing system of town local government.
Municipal Districts will cover the entire territory of each county, reflecting European norms, uniting towns with their hinterlands, removing outdated boundaries and ending the anomalous treatment of some larger urban centres.
Recommended Local Electoral Areas by Size - see page 12 of report.


text:
THE standard of bereavement care in general practice has been challenged by new research published in Family Practice.
The study was the first randomised controlled trial (RCT) of a bereavement intervention in general practice. Undertaken within the Danish national health system, it aimed to evaluate the efficacy of a bereavement intervention delivered by GPs, and the GPs' ability to diagnose severe grief.
The study did demonstrate greater improvements in grief scores for patients in the intervention group than those in the control group, but the difference was just below statistical significance. This finding is consistent with meta-analyses of RCTs of various interventions for the prevention and treatment of complicated grief that demonstrate modest effectiveness.
However, the recent research failed to show improvement in the GPs' diagnostic abilities in recognising prolonged grief disorder, otherwise known as complicated grief — a particularly severe form of grief that has been proposed as a distinct mental disorder for the DSM-5.
This form of grief, experienced by about 10% of bereaved persons, is characterised by a risk profile and a distinct symptomatology, including severe separation distress with intense yearning. Along with other forms of severe grief, complications include significant physical and mental illness such as cardiac crises, exacerbation of existing illness, substance abuse, social dislocation and suicide.
Unlike adaptive grief, which affects about 80% of bereaved persons, complicated grief does not recede over time. Without therapy, it runs a prolonged course with multiple complications. Psychosocial interventions are considered effective and recommended for all those experiencing severe grief and for those otherwise needing support.
his has direct relevance for GPs. As family doctors, we regularly encounter bereaved patients: we live the bereavement with them as we attend to their dying family members; and we pick up the pieces of the complications of their grief months, or even years, later.
A preliminary study of general practice patients that I conducted in Adelaide found around 25% to be experiencing grief from a death loss.
GPs are often the professional of choice for those experiencing grief as they are available and affordable. They are uniquely equipped with their prior comprehensive knowledge of the patient, diverse clinical skills and expertise in chronic problem management, and theoretically are well placed to care for the bereaved in the community.
Yet the Danish study poses the question: why were the results so minimal? Other than methodological difficulties common to bereavement research, the authors say the answer is in the nature of the intervention and insufficient GP expertise.
Translating this from the Danish national health system to the Australian context, would we do any better? Are we aware of who is most at risk? Where is our training?
My particular clinical focus is on grief counselling, but I had to go outside my discipline to the funeral industry, psychology, the social sciences, psychiatry and palliative care for information and training.
Are we complicit with our death-denying society in neglecting an important area of clinical practice? After all, bereavement care is embodied in the Australian national mental health and suicide prevention strategies.
With the known morbidity of severe grief, demonstrated evidence for the effectiveness of bereavement care and the substantial prevalence of bereaved people in the general practice population, it behoves us to take action.
We need training programs evaluated for their efficacy, a body of research literature in the general practice setting, and diagnostic tools and therapeutic guidelines evaluated with appropriate instruments. Cost–benefit may be impossible to measure when the multidimensional long-term possible outcomes are considered, but the literature evaluating illness prevention would support the initiative.
This latest study highlights the need for general practice to formally recognise its role in grief and implement an evaluated program of bereavement care.
Dr Sheila Clark is a GP with a special interest in grief counselling, based in Adelaide, and adjunct senior lecturer with the Discipline of General Practice at the University of Adelaide.
Posted 22 October 2012


text:
If you opt to watch the video instead, scroll right down to the bottom of the page or click right here »»»» but it is advisable to learn this article utterly for higher understanding. Passives for this construct are lined by Spiritual Attunement (for mana regeneration), Pierce The Veil (for an increased harm increase) and Spirit Vessel (for cooldown discount on Spirit Walk and the power to potentially cheat dying every 90 seconds). This is very important to remember when you've got employed someone to build enterprise web site for you.
The JQuery website has a complete documentation and tutorials to get even an absolute beginner in programming to get the ball rolling with this library. Post your footage here if you'd like to assist set nice pictures free for shows, re-interpretation and connecting with others. But trust me, should you can read and write in easy English, you are able to do this your self without having to pay hundreds of dollars to any web site designer to build your website for you!!
Any website template order consists of complete e-mail support in addition to access to our searchable support website with assist for all points of web site setup. Note that when you preview your web site, it is not going to present any cheap internet-web page as a result of you have not imported your web site yet and do a few of the essential steps I will present you as you learn alongside. I started utilizing this tool and it turns out it's a easy internet improvement tool that is all plug and play… It's hard for me to imagine a web site being ten occasions extra stunning than what you can construct with Strikingly.
Sure, there are some technical hurdles to overcome, but once you've got acquired it arrange (and Hostgator help is very helpful indeed), maintaining a website constructed on WordPress software isn't any tougher than maintaining a Blogger weblog. For free blogs with the potential for making some revenue sharing and cash from promoting, I would choose Blogger.
However it has a diminishing popularity, since having been superseded by web requirements (HTML5) and is not supported by main mobile working methods iOS (Apple) and Android (Google). The website is offered from smartphones and tablets, there are constructed-in contact forms that allow prospects to contact our magnificence experts immediately. While Hosting Ireland will at all times do it is upmost to verify customers receives an AdWords voucher, supply cannot at all times be assured.


text:
151226 Crayon Pop's Japanese Photobook "pop in book" Information Revealed
December 26, 2015 | News | 28 Comments ||
Crayon Pop, along with their 1st Japanese album, are releasing a photobook titled "pop in book". It is 144 pages. It will be released on 20 January 2016, the same day as the Japanese album. Cover and sample photos below.
It can be bought here.


text:
Foundation for Louisiana is the people's foundation. We tackle the issues that most deeply impact our communities, advocating alongside Louisianans to chart our own futures. We are transparent and accountable to our community around what we fund, who we fund, and how we make funding decisions. We have strong, stated, actualized values. We use our power responsibly, acknowledge it, and push it outward. We are Black-led and honor the knowledge of people of color, women, two-spirit and transgender individuals -- and the many ways in which these identities intersect. We are bold in our analysis and movement towards freedom, amplifying the lived experiences of Louisianans closest to the work. We bring people with us, and people bring us with them. We will continue to be courageous.
FREEDOM. Our work is rooted in the legacy of abolition movements that have existed in Louisiana for hundreds of years. We will press on until our state sees true collective freedom for all Louisianans.
JUSTICE. Achieving justice for all Louisianans requires effective public policy and systemic change, a decolonial framework, and an intersectional understanding of systems of oppression. We are interconnected, and our work must address legacies of slavery and anti-Black racism, and acknowledge that we are on Native land.
ACCESS. Removing barriers and creating paths to resources and opportunities for those who have been denied access to them is necessary for systemic change.
KNOWLEDGE. The grassroots wisdom of Louisiana residents is our most valuable resource. Given appropriate support, communities can and will solve their own problems and chart their own futures.
LIVED EXPERIENCE. Those who are most impacted by injustice are also best equipped to lead positive change in their communities. As such, our board and staff are representative of our communities across Louisiana.
TRANSPARENCY. Being clear and open about our work holds us accountable to each other and to our communities, and maintains our integrity as an organization.
DIGNITY. Individuals and families have the right to thrive in everyday life, and amidst both natural and man-made disasters.
COMMITMENT. Continuous individual and collective growth improves our work. We are committed to doing our best and always aim to do better.
COURAGE. We acknowledge the longevity of our struggles. We find the strength necessary to persevere in the face of violence by remembering that we walk in the footsteps of our ancestors.
Our Board of Directors have strong ties to every part of the state, as well as leadership skills, business expertise, and philanthropic experience that has been recognized nationally and throughout the world. This powerful combination of local investment and talent makes the Board one of Foundation for Louisiana's strongest assets.
Learn more about our Board of Directors in their bios.
Pamela Jenkins, Ph.D., Chair, Research Professor of Sociology, Women's Studies Program, University of New Orleans
Linetta J. Gilbert, Chair Emeritus; Managing Partner, Gilbert & Associates
Ambassador James A. Joseph, Chair Emeritus
Jainey K. Bavishi, Director of the New York City Mayor's Office of Resiliency
Lieutenant Gen. Russel Honore, Retired
Telley S. Madina, Senior Policy Officer, Oxfam America
May Nguyen, Development Director, Asian Pacific Environmental Network
Alvertha Bratton Penny, Principal, Alvertha Penny and Associates
Mark L. Quinn, Conrad N. Hilton Endowed Chair in Entrepreneurship and Assistant Professor of Entrepreneurship at Xavier University; director, Xavier University Entrepreneurship Institute
We depend on our dedicated staff to carry out FFL's mission. The Foundation's high-engagement team works closely with Louisiana residents to provide resources in support of their work . The staff brings a wide array of experience and talent to our work and shares an abiding commitment to building a better Louisiana.
Learn more about our Staff in their bios.
Flozell Daniels, Jr., President and CEO
Charmel Gaulden, Chief Operating Officer
Dana Delpit, Chief Financial Officer
Laquitta Bowers, Programs Associate
Caressa Chester, Coastal Community Programs Associate
Asti Davis, Climate Justice Network Engagement Manager
Michele Garval, Staff Accountant
Ra'Shaud Haines, Community Investment Fund Manager
Keeta Jackson, Racial Justice Programs Associate
Desmond Johnnie, Grants and Fiscal Sponsor Manager
Maria Cherry Rangel, Director of Strategic Initiatives
Nicole Washington, Executive Assistant to the President & CEO
Liz Williams Russell, Coastal Community Resilience Director


text:
Link Building is a process of improving search engine rankings and different strategic tactics are used to get quality websites to link to the certain website. In this way a webmaster may improve back links of the websites which is helpful to enhance web-rankings into multiple search engines e.g. Google, MSN, Yahoo etc. the link builder has to adopt different strategies of search engine optimization to boost up the popularity of the websites among the visitors and search engines. The unique web content and link exchange are valuable features of link building to improve the quality and popularity of the websites. The link builder has to find out relevant data of authority sites which may refer as resource to visitors to the specific kind of website.
Our SEO Company serves the customers by offering high quality links with optimum relevancy and business popularity. Our dedicated search engine optimizers are expert in employing different techniques of link building and you would find your websites with maximum site indexes. We offer online technical support to enhance link popularity of the websites of our clients. Our Link building services help to promote your online business by linking different relevant websites to your site. We use different strategies and multiple anchor text and actual thematic description of the websites to develop relevant links to the website. we use all kinds of link building tactics including reciprocal link exchange programs, buying links, directory submissions, SEO-Type articles and one way link promotion programs etc. There is a need of research-based study of the website in order to find out relevant and potential back link' data. The professional search engine optimizers have to plan new criteria every month to maximize the visibility and popularity of websites into search engines.
Linkage is referred to a connection of well-authorized sites with other sites via inbound and outbound links and if the website has optimal linkage to other sites, there would be high ranks of the website into search engines resultantly. Every webmaster has to deal with most updated link building strategies which are important to promote specific criteria of SEO algorithms and web-rankings for multiple keywords which are assistive tools to increase link popularity of the website to maximum levels. The techniques of link exchange are very beneficial to target the potential customers for the enhancement of sales and you can promote your online business with low-rated budget rather than other advertising campaigns. Apparently link exchange campaign seems simple and effortless job but there is need of in-depth research and analysis of your link partners in order to ensure credibility and popularity of the websites. The link builder has to consider the quantity and quality of links and well-balanced formation of linkage with low-ranked and high-ranked websites may generate natural way of link building and the major search engines are likely to accept such kind of link building to increase web-rankings. We offer reliable link building services to promote web rankings, user-friendly traffic and internet visibility for long term. We provide all web promotion tools including one way linking, reciprocal linking or link exchange, text links, buying links and directory submission of articles etc. You would find fine-quality service of search engine optimization in cost-effective rates if you get services of our professionals!
Contact Our Link Building Experts To get more


text:
Home Zone
All students who live within the home zone shown on the list of roads published on the School Zone page shall be entitled to enrol at the school.
Each year, applications for enrolment for the following year from in-zone students, will be sought by a date that will be published in a daily or community newspaper circulating in the area served by the school. This will enable the Board to assess the number of places that can be made available to students who live outside the home zone.
For more information about enrolment at St Heliers School or an application form, please contact the school.
Pre-school Visits
As a student nears their fifth birthday, pre-school visits are encouraged. One or two morning visits can be arranged. The Deputy Principal should be contacted to arrange these.
International Student Enrolments
For information on International Student enrolments go to International Students
Out of Zone Enrolments
Each year the Board will determine the number of places that are likely to be available in the following year for the enrolment of students who live outside the home zone. The Board will publish this information by notice in a daily or community newspaper circulating in the area served by the school. The notice will indicate how applications are to be made and will specify a date by which all applications must be received.
NB: There are no places available for out of zone students for 2019 or 2020.
Applications for out of zone enrolments will be processed in the following order:
- First Priority. This priority category is not applicable at this school because the school does not run a special programme approved by the Secretary.
- Second Priority will be given to applicants who are siblings of current students.
- Third Priority will be given to applicants who are siblings of former students.
- Fourth Priority will be given to applicants who are children of Board employees.
- Other Priority will be given to students who have been accepted for enrolment in the following special programme run by the school and approved by the Secretary for Education.
If there are more applicants in the second, third, fourth or fifth priority groups than there are places available, selection within the priority group will be by a ballot conducted in accordance with instructions issued by the Secretary under Section 11G(1) of the Education Act 1989. Parents will be informed of the date of any ballot by notice in a daily or community newspaper circulating in the area served by the school.


text:
A new survey of the top 10 cities with solar potential has Texas making a strong showing. Heading up the pack at number 1 is Houston, while San Antonio and Dallas take 4th and 9th place, respectively.
The survey was conducted by Google using its Project Sunroof tool, which shows the solar potential of individual rooftops. Here's a look at the Top 10:
if you add the numbers for the three Texas cities, you could generate a little over 35,000 GWh (gigawatt-hours) of electricity in a year. And those panels would last 25-30 years. That's as much electricity as the state already generates in a year from nuclear, coal, wind, and solar.
Let's say it more clearly: Installing solar panels on all the suitable rooftops in Houston, San Antonio, and Dallas could generate nearly all the electricity Texas needs, for decades to come.
It's important to note the tool only measures incoming sun, not the potential for saving money with solar. That's where we come in.
Saving money with solar in Texas
The Lone Star State gets a lot of sun, but going solar on your roof can be difficult. That's because the state's deregulated energy market means low prices, which in turn means low savings with solar. Still, if you live near one of the big cities, you have options.
There are even electric utilities that will buy your solar power for the full retail rate. And Texas is so sunny, you don't need a big system to make a lot of electricity.
To get started, connect with a trusted local installer to see if solar is right for your roof.
Learn more about solar in Texas
Check out the two best ways to go solar in Texas below, then go to our special Texas solar page to read more about Texas solar laws, incentives, and savings estimates.
Last modified: March 17, 2017
One thought on "Texas has 3 of the nation's top 10 cities for solar potential"
When I do a study my net energy savings (Austin area) is -16000 over 20 years. I totally disagree with subidies (Stealing from me as a tax payer and forcing something down our throats). If it can't survive on market economics it doesn't need to be here. Solar is great for areas where bringing the grid to a location is cost prohibitive, or maybe at utility scales (MW Level) but the cost to get it on a local roof is just not feasable at current prices and energy levels.


text:
Went to the open knitting session at Down Cellar this afternoon and stayed an extra hour so that I could finish all the knitting on the bag. When I got home, after supper and walking the dog, I sewed all the loose ends in and sewed 6 buttons around the 2 flaps I knitted to hold in the bamboo-ring handles. I also crocheted 2 rings attached to one of the flaps. There will be a third ring for the final button on that side, and then there will be 3 more rings to go around the buttons on the other side.
The final product looks incredible, and I can't wait to finish it and show it to you. Won't be long now.


text:
- Outdoor style
- Lifestyle
- Garden essentials
- Wildlife
- Pets
- Gifts
- Kids in the garden
- Summer
- Sale items
- Best sellers
Garden essentials >
Store your twine in style with this vintage-style string dispenser. Made from cast iron and painted white with an unusual bird finial, this lovely string dispenser has an aged effect and looks gorgeous on any shelf indoors or out in the potting shed. This string dispenser comes with jute twine and a handy pair of antique-style metal scissors so you can cut the length you need. The prefect gift for any gardener. 12.7 x 12.7 x 21 cm


text:
Corner Records
Solothurnerstr. 50
CH, 4053 Basel
Corner Records
Solothurnerstr. 50
CH, 4053 Basel
What is it about corners? Places of chance encounters, moments of uncertainty about what may lay on the other side. Two directions converge and intersect and new directions reveal themselves.
In 2006 a series of coincidences and convergences brought Swiss producer Shaka and Canadian producer Breandan Davey together. Recognizing their convergent personal styles of music and their belief that modern electronic music must take on new directions, they formed an idea of a new label which by 2007 began to take shape, and Corner Records was born. >>>
Corner Records was founded in order to provide a viable marketing vehicle to talented musicians that push musical boundaries, whom due to the underdeveloped infrastructure of the independent electronic music industry receive little recognition or compensation for their efforts.
As Corner Records was founded by artists, the company believes strongly in honesty and integrity in dealing with our artists and the music we release. Corner believes artists should receive a fair return for their work and actively seeks out opportunities for touring and licensing of material in order to expose the artist and to help provide a sustainable income from their music.


text:
this is the next song (The livings)
"This is the next song" is a typical sentence the singer of a band would say to introduce the title of the coming song, after which the audience would be silent and expecting… Jianan Qu "writes" the sentence with a wet cleaning rag on the white museum wall. Leaving the audience to the fading sentence, the piece questions the role of expectation in the art space. As it dries, the wall itself becomes the performer.
Photo & Video : Dominik Galleya
Performance, 2017


text:
Welcome to ARISCOM
The Association for Research in Social Sciences, Commerce and Management (ARISCOM), is an emerging research initiative established with the objective of promoting scientific research through various workshops, seminars, conferences, training programmes etc. vis-a-vis publishing journals, edited books, occasional papers, monographs, white papers and case studies. The Society also aims at undertaking research projects on leading socio-economic and business management issues in coordination with various government departments, public and private undertakings and other research organisations.
ARISCOM Journals
ARISCOM publishes two Journals: ARISCOM Journal of Social Sciences (AJSS) and ARISCOM Journal of Management (AJM). The Society has received ISSN 2581-6365 for AJSS, while the same is under process for AJM. Both the Journals are registered with the Registrar of Newspapers of India (RNI No. of AJSS: JHAENG/2018/75342, RNI No. of AJM: JHAENG/2018/75345). We thank all our stakeholders, patrons and well wishers for their continued support and faith in our purpose and in our activities.


text:
Home » Careers » Available positions
SOGESE is operative on the whole national territory and is growing abroad. We constantly look for professionals all over the main Italian and European areas. Our group offers great opportunities for people willing to gain experience and to go deeper into the world of dry containers and refrigerated containers all over the main Italian and European areas. If you are a dynamic person, with an enterprising spirit and you wish to work in a creative and dynamic environment, then have a look at our open positions and send us your resume.
SOGESE is looking for a carpenter and welder with work experience in damage estimation and reparation of shipping containers. The candidate must have knowledge of the standard container estimation criteria(IICL/CW/CIC). The knowledge of the related technical English language is required.
To apply for this position please click on the following link: APPLICATION FORM.
Sogese is looking for a senior reefer technician with, at least, two years of experience in the repair and maintenance of reefer container machines . The candidate must have a deep knowledge of the common reefer machines as well as of their parts and electric circuits. He must be familiar with spare parts and with their required procedures for issues related to the management of the warranties. The knowledge of the related technical English language is required.
(*) required field
I agree the use of my personal data


text:
|McDonald's France California & Chicken
|McDonald's American Summer 2014 Promo
Consumed on 20 July 2014
Location - McDonald's Evreux, Normandy, France
Combo Price - 8.80EUR = $11.80USD
Calories - ~675kcal
|McDonald's France Receipt
|I wonder if they ran out of promo boxes, since this was nearing the end of the run
My wife and I made out way of Paris to Normandy to attend my friends wedding (the reason why we were in France). The day after the wedding, we spent a leisurely day in Évreux, the largest town near the wedding venue. Since it was a sleepy Sunday in a small town in the French countryside, which meant was only a single other restaurant open for lunch and it didn't look all that impressive, so it was a perfect opportunity to try the two "American Summer" promos, the first of which I'll review was the "California & Chicken". Although released in the same series, we didn't get the Classic Chips this time, since they were such a disappointment when I ordered them with The 280 Recette Fromagere.
I guess the "California" in the name must have been the special Bacon and Avocado sauce which topped the burger since the "Chicken" was just a standard chicken piece used in other burgers. Unlike some of special-sauced burgers in Asia, this one actually had a generous serving of the special sauce, but unfortunately...it wasn't any good and the burger probably would have been better with half the amount provided. Going in, I knew it was a Bacon-Avocado sauce, but my wife went in blind. When I took my first bite, other than being a lukewarm burger (there were hardly any other customers, and we were in the countryside, I can see why it sat for a while), it didn't turn me off all that much. I didn't think it was great, but I didn't think it was that bad either. The sauce was heavy on the "bacon" and very light on the avocado. So much in fact that if you told me that it was purely a bacon sauce, I wouldn't have questioned you otherwise. The bacon, wasn't a fresh bacon either, it tasted like those bacon bits you can have on your salad. I also believe that it was similar to the sauce served along with the fries, that it was fresh cream based, rather than mayonnaise based since it had a tangy after-taste which I've never noticed with any of the mayo based sauces. I have been unable to find any ingredient list for this sauce, so if you know for certain, leave a comment, or message me on Twitter.
The processed cheese slice was supposed to have bits of pepper inside, and although you could see them, it added nothing to the taste whatsoever. I think this may have been because the sauce was so overpowering.
The lettuce was green I'll give it that, but that's all the praise I'll give, because it was very limp and soggy. My wife took a bite, thought that it was pretty gross, but praised the white meat chicken patty (which is a rarity in Singapore) but since we had a number of other things to try, didn't elaborate any further, so we moved on to other items.
|A surprisingly thin piece of chicken for a promo
After a couple minutes, I moved back to California & Chicken, where it had progressed from lukewarm, to that point where something is no longer warm, but you can't consider it ice cold either, slightly higher than room temperature. But let me be clear, it's not like my wife and I had a 1 hour conversation between our first bites and the second, this couldn't have been more than 3-4 minutes. Either I didn't notice it before or it was masked because the burger was warmer, but the sauce had a terrible, off-putting smell. I took another bite of the burger, and I actively disliked it, which was a big change from the first. I asked my wife as she took her second bite, if she thought it also smelt like sweaty armpit (the closest comparison I could think of). She immediately put the burger back down, and that's where it remained until we left, although I did try to dip a couple fries in the sauce to see if I could get ANY avocado flavour out of it...I failed). I guess the combination of artificial bacon, (sour) cream, and whatever avocado was supposed to be in the sauce just didn't fair well with the temperature change. That, or it was made right when they started lunch service (about 90 minutes prior) and had been festering under a heatlamp until our arrival.
Rating - 1.5/5
As terrible as this burger was, at least the restaurant itself was cool enough. It couldn't have been more than a couple years old.
|McDonald's Évreux Exterior
|McDonald's Évreux Interior


text:
20 generic drugs taken off Portuguese market amid clinical trial concerns
January 30, 2015 2:01 am
LISBON, Jan. 29 — Twenty generic drugs have been withdrawn from the Portuguese market following concerns raised by the European Medication Agency (EMA) about clinical trials carried out by Indian drug maker GVK Biosciences, Portugal's National Medication and Healthcare Products Authority (Infarmed) said in a statement issued Wednesday.
The EMA published last Friday a list of hundreds of generic drugs manufactured by GVK Biosciences with the recommendation that their sale be suspended in European markets.
The recommendation followed an inspection of GVK Biosciences' premises in India, which found irregularities in the company's clinical trials methods.
The inspection of the Indian company found manipulation of results of electrocardiograms during clinical trials.
A total of 64 drugs on the list have been or are currently sold in Portuguese pharmacies. Of those, Infarmed said additional information that proves the safety of the generic drugs was not available for 24, of which only 20 are currently being sold.
"Despite not having information on evidence, they are putting public health at risk. While awaiting a final decision from the European Commission, based on the principal of precaution, Infarmed requests holders of the market authorizations voluntarily to remove the 20 medications sold in Portugal," the statement said.
The withdrawn medications include analgesics, antidepressants, anti-allergy drugs, as well as drugs to treat angina, schizophrenia, bipolar disorder, Parkinson's disease, osteoporosis and Alzheimer's disease. (PNA/Xinhua)


text: VS Battles… Editing Template:! 0 You do not have permission to edit this page, for the following reasons: The action you have requested is limited to users in one of the groups: Autoconfirmed users, FANDOM Staff, FANDOM Helpers, Wiki Managers, Content Team Members. Please log in to edit this wiki.Joining VS Battles Wiki is free, and it only takes a minute.We hope that you sign in, and become a member of the community!Click here to log in or create an account You must confirm your e-mail address before editing pages. Please set and validate your e-mail address through your user preferences. more + You can view and copy the source of this page: <onlyinclude>|</onlyinclude> {{documentation}} Templates used on the current version of this page: Template:!/doc (view source) Template:Documentation (view source) Template:T (view source) Template:T/piece (view source) Template:Tocright (view source) Return to Template:!. Retrieved from "https://vsbattles.fandom.com/wiki/Template:!" Edit summary Preview Mobile Desktop Show changes


text:
It is said that a picture says about 1000 words then think about what video will do. Putting your video online can help you convey your messages to your audience. Here are few reasons that help you understand why you need a video online. Read More
Why do you need Video Online?
Video Creates Sales
Video Creates Sales
Video brings people in touch with the product without having to experience it in person. It emotionalises the viewers decisions and bring confidence and familiarity to the brand.
52% of consumers say that watching product videos makes them more
confident in online buying decisions.1
More than three out of five consumers will spend at least two minutes
watching a video that educates them about a product they plan to
buy, and 37% will watch for more than three minutes.2
Businesses find that shoppers who view video are 174% more
likely to buy than viewers who did not.3
Online retailers find that 33% of online sales came from the
13% of site visitors who viewed video.4
34% of clothing shoppers are more likely to buy after viewing an
online video ad, versus 16% after watching an ad on TV.5
1 Internet Retailer. Online Videos Help Build Confidence in Purchases.
2 Marketing Charts. Product Videos Found Boosting Purchase Confidence Among Viewers.
3 Retail TouchPoints. Retail TouchPoints Channel Innovation Awards 2012.
4 NRF Stores. Set a Spell: BizChair.com Gives Customers a Closer Look.
5 ReelSEO. Back-to-School Shopping Trends: Video is Key to Retail Clothing Sales for 2012 [Study].
Are You using YouTube for Business?
Are You using YouTube for Business?
- More than 1 billion unique users visit YouTube each month
- Over 6 billion hours of video are watched each month on YouTube—that's almost an hour for every person on Earth
- 100 hours of video are uploaded to YouTube every minute
- 80% of YouTube traffic comes from outside the US
- YouTube is localized in 61 countries and across 61 languages
- According to Nielsen, YouTube reaches more US adults ages 18-34 than any cable network
- Millions of subscriptions happen each day. The number of people subscribing daily is up more than 3x since last year, and the number of daily subscriptions is up more than 4x since last year
- 500 years of YouTube videos are watched on Facebook per day
- 700 YouTube videos are shared on Twitter a minute.


text:
Skip to Main Content »
Dip-n-Go Sludge is a fast-acting mandrel release for lampworkers. Works with solid and hollow mandrels of all sizes. Provides an easy release when cool, and a strong hold while working with the flame.
So far, you have no items in your cart.
Adding $200.00 of items to your Cart will move you into the 10% discount tier for eligible items.
© Bullseye Glass Co.


text:
Shipping information
Receive your purchases in 10-12 working days after your order has been placed.
Exchange and refund
Exchange or refund items within 7 days from the delivery date. All items must be returned in perfect condition with the label attached along with a copy of your initial invoice. In case items are not available for an exchange, you will be refunded. Your account will be credited within 15 days.
All sale items are final sale. Are not exchangeable or refundable.
The return shipping costs are at the customers charge. We recommend shipping your return with a service that provides package tracking to avoid delays and lost. Please note that a package refusal does not suffice as a request for a refund. We reserve the right to decline your return if these Sales Conditions are not met. Please contact us if you ve any concerns or questions regarding your exchange or return.
Please send your returned goods: Natalie Constantinidou,12 Emiliou frankou st,Limassol 3120,Cyprus


text:
Lenny Gray has been a professional bassist for over 30 years. Although most of his experience is with local bands he has shared the stage with such national musicians as Benny Bailey, Victory Wooten, Roy "Future Man" Wooten, Howard Levy, Pharez Whitted and jazz trombonist Slide Hampton. Lenny has been teaching bass guitar for 7 years. He enjoys sharing his knowledge of the instrument and watching students grow. Lenny is pleased to be among the excellent teaching staff at Stebal Drums.
Teacher Bios


text:
Small set of utilities. Hangs in system tray. 3. Alarm clock:.
Free download of PasClock 2.7, size
2.32 Mb.
AutoTyping Word is a handy and reliable application designed to make word suggestions as you type text. . Free download of AutoTyping Word 1.2, size 0 b.
With the program "I-Wallpaper Changer" it is easy to install as wallpaper of a desktop of a pictures, video (including flash), local html-pages or web links (for example your web-site). It is possible to create the lists of files for wallpaper and to be switched between them. Files and folders can be added in the list dragging from the. Free download of I-Wallpaper Changer 1.1, size 1.60 Mb.


text:
Meare Court is a 17th Century grade 2 listed manor house with beautiful original features. These include an elm medieval rustic screen on the third floor and a beautiful Georgian panelled dining room. There are original flagstone floors, beams and a huge open fireplaces. Meare Court is ideal for big house weekends and large group stays, featuring its own private hot-tub in garden. Free wireless internet.
- 5 bedrooms:
- 1 king size + single ensuite
- 2 king size + single,
- 1 twin
- 1 large elm panelled room with 2 singles and a four poster bed.
- 1 bathroom with bath and shower.
- 1 shower room.


text:
Concept: Hereditary nonpolyposis colorectal cancer
Adiposity and cancer at major anatomical sites: umbrella review of the literature
- BMJ (Clinical research ed.)
- Published over 3 years ago
- Discuss
Objective To evaluate the strength and validity of the evidence for the association between adiposity and risk of developing or dying from cancer.Design Umbrella review of systematic reviews and meta-analyses.Data sources PubMed, Embase, Cochrane Database of Systematic Reviews, and manual screening of retrieved references.Eligibility criteria Systematic reviews or meta-analyses of observational studies that evaluated the association between indices of adiposity and risk of developing or dying from cancer.Data synthesis Primary analysis focused on cohort studies exploring associations for continuous measures of adiposity. The evidence was graded into strong, highly suggestive, suggestive, or weak after applying criteria that included the statistical significance of the random effects summary estimate and of the largest study in a meta-analysis, the number of cancer cases, heterogeneity between studies, 95% prediction intervals, small study effects, excess significance bias, and sensitivity analysis with credibility ceilings.Results 204 meta-analyses investigated associations between seven indices of adiposity and developing or dying from 36 primary cancers and their subtypes. Of the 95 meta-analyses that included cohort studies and used a continuous scale to measure adiposity, only 12 (13%) associations for nine cancers were supported by strong evidence. An increase in body mass index was associated with a higher risk of developing oesophageal adenocarcinoma; colon and rectal cancer in men; biliary tract system and pancreatic cancer; endometrial cancer in premenopausal women; kidney cancer; and multiple myeloma. Weight gain and waist to hip circumference ratio were associated with higher risks of postmenopausal breast cancer in women who have never used hormone replacement therapy and endometrial cancer, respectively. The increase in the risk of developing cancer for every 5 kg/m(2) increase in body mass index ranged from 9% (relative risk 1.09, 95% confidence interval 1.06 to 1.13) for rectal cancer among men to 56% (1.56, 1.34 to 1.81) for biliary tract system cancer. The risk of postmenopausal breast cancer among women who have never used HRT increased by 11% for each 5 kg of weight gain in adulthood (1.11, 1.09 to 1.13), and the risk of endometrial cancer increased by 21% for each 0.1 increase in waist to hip ratio (1.21, 1.13 to 1.29). Five additional associations were supported by strong evidence when categorical measures of adiposity were included: weight gain with colorectal cancer; body mass index with gallbladder, gastric cardia, and ovarian cancer; and multiple myeloma mortality.Conclusions Although the association of adiposity with cancer risk has been extensively studied, associations for only 11 cancers (oesophageal adenocarcinoma, multiple myeloma, and cancers of the gastric cardia, colon, rectum, biliary tract system, pancreas, breast, endometrium, ovary, and kidney) were supported by strong evidence. Other associations could be genuine, but substantial uncertainty remains. Obesity is becoming one of the biggest problems in public health; evidence on the strength of the associated risks may allow finer selection of those at higher risk of cancer, who could be targeted for personalised prevention strategies.
Global trends and predictions in ovarian cancer mortality
- Annals of oncology : official journal of the European Society for Medical Oncology / ESMO
- Published about 4 years ago
- Discuss
Over the last two decades, ovarian cancer mortality rates have levelled or declined. There are, however, persisting and substantial differences in ovarian cancer patterns and trends.
The association between talc use and ovarian cancer: a retrospective case-control study in two US states
- Epidemiology (Cambridge, Mass.)
- Published almost 5 years ago
- Discuss
Multiple studies of ovarian cancer and genital talc use have led only to consensus about possible carcinogenicity. Seeking greater clarity, we examined this association in 2041 cases with epithelial ovarian cancer and 2100 age-and-residence-matched controls.
Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts
Lynch syndrome (LS) is characterised by the development of colorectal cancer, endometrial cancer and various other cancers, and is caused by a mutation in one of the mismatch repair genes: MLH1, MSH2, MSH6 or PMS2. In 2007, a group of European experts (the Mallorca group) published guidelines for the clinical management of LS. Since then substantial new information has become available necessitating an update of the guidelines. In 2011 and 2012 workshops were organised in Palma de Mallorca. A total of 35 specialists from 13 countries participated in the meetings. The first step was to formulate important clinical questions. Then a systematic literature search was performed using the Pubmed database and manual searches of relevant articles. During the workshops the outcome of the literature search was discussed in detail. The guidelines described in this paper may be helpful for the appropriate management of families with LS. Prospective controlled studies should be undertaken to improve further the care of these families.
A randomised controlled trial comparing surgical intervention rates between two protocols for the management of asymptomatic adnexal tumours in postmenopausal women
INTRODUCTION: Detection of asymptomatic adnexal tumours in postmenopausal women has increased due to wider use of diagnostic ultrasound and imaging quality improvements. Reliable methods to differentiate between benign and malignant tumours are required to avoid delays in treating ovarian cancer and to prevent unnecessary interventions for benign lesions. In the UK, the Royal College of Obstetricians and Gynaecologists has issued guidance for the management of adnexal cysts in postmenopausal women, which is considered standard in routine clinical practice. The protocol utilises the Risk of Malignancy Index to assess the risk of adnexal lesion being malignant. This protocol has a relatively high intervention rate in order to avoid a delay in a cancer diagnosis. The Simple Rules Protocol designed by International Ovarian Tumour Analysis Group reports a low false-positive rate in the diagnosis of ovarian cancer without a loss of sensitivity and therefore has the potential to reduce unnecessary interventions in asymptomatic postmenopausal women with benign cysts. METHODS AND ANALYSIS: 140 postmenopausal women aged 40-80, with incidentally detected adnexal tumours on ultrasound scan will be recruited to this study. They will be randomly allocated, to be assessed and managed according to either of the two protocols under investigation. In both arms of the study the tumours will be classified into three groups: high, intermediate or low risk of malignancy. Women with high risk of malignancy will be referred for management in a tertiary cancer centre, women with low-risk tumours will be managed expectantly, while those with intermediate risk findings have surgery in their local hospital units. Analysis will be on an intention-to-treat basis. ETHICS AND DISSEMINATION: Research ethical approval was granted by the North London Research Ethical Committee 2 (10/H0724/48). Trial results will be published according to the CONSORT statement. TRIAL REGISTRATION NUMBER: Registration at http://www.controlled-trials.com/ISRCTN89034131/. ISRCTN89034131.
Aurora kinase A mediates epithelial ovarian cancer cell migration and adhesion
Aurora kinase A (AURKA) localizes to centrosomes and mitotic spindles where it mediates mitotic progression and chromosomal stability. Overexpression of AURKA is common in cancer, resulting in acquisition of alternate non-mitotic functions. In the current study, we identified a novel role for AURKA in regulating ovarian cancer cell dissemination and evaluated the efficacy of an AURKA-selective small molecule inhibitor, alisertib (MLN8237), as a single agent and combined with paclitaxel using an orthotopic xenograft model of epithelial ovarian cancer (EOC). Ovarian carcinoma cell lines were used to evaluate the effects of AURKA inhibition and overexpression on migration and adhesion. Pharmacological or RNA interference-mediated inhibition of AURKA significantly reduced ovarian carcinoma cell migration and adhesion and the activation-associated phosphorylation of the cytoskeletal regulatory protein SRC at tyrosine 416 (pSRC(Y416)). Conversely, enforced expression of AURKA resulted in increased migration, adhesion and activation of SRC in cultured cells. In vivo tumor growth and dissemination were inhibited by alisertib treatment as a single agent. Moreover, combination of alisertib with paclitaxel, an agent commonly used in treatment of EOC, resulted in more potent inhibition of tumor growth and dissemination compared with either drug alone. Taken together, these findings support a role for AURKA in EOC dissemination by regulating migration and adhesion. They also point to the potential utility of combining AURKA inhibitors with taxanes as a therapeutic strategy for the treatment of EOC patients.Oncogene advance online publication, 21 January 2013; doi:10.1038/onc.2012.632.
Overexpression of YAP and TAZ Is an Independent Predictor of Prognosis in Colorectal Cancer and Related to the Proliferation and Metastasis of Colon Cancer Cells
Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) are nuclear effectors of the Hippo pathway. Although they are abundantly expressed in the cytoplasm and nuclei of human colorectal cancer (CRC), and related to tumor proliferation status, there have been few studies on the predictive role of YAP and TAZ expression on the overall survival of patients with CRC. This study investigated YAP and TAZ expression in both CRC patients and colon cancer cell lines, and assessed their prognostic value.
Refining Ovarian Cancer Test accuracy Scores (ROCkeTS): protocol for a prospective longitudinal test accuracy study to validate new risk scores in women with symptoms of suspected ovarian cancer
Ovarian cancer (OC) is associated with non-specific symptoms such as bloating, making accurate diagnosis challenging: only 1 in 3 women with OC presents through primary care referral. National Institute for Health and Care Excellence guidelines recommends sequential testing with CA125 and routine ultrasound in primary care. However, these diagnostic tests have limited sensitivity or specificity. Improving accurate triage in women with vague symptoms is likely to improve mortality by streamlining referral and care pathways. The Refining Ovarian Cancer Test Accuracy Scores (ROCkeTS; HTA 13/13/01) project will derive and validate new tests/risk prediction models that estimate the probability of having OC in women with symptoms. This protocol refers to the prospective study only (phase III).
The potential of circulating tumor DNA methylation analysis for the early detection and management of ovarian cancer
- Genome medicine
- Published almost 3 years ago
- Discuss
Despite a myriad of attempts in the last three decades to diagnose ovarian cancer (OC) earlier, this clinical aim still remains a significant challenge. Aberrant methylation patterns of linked CpGs analyzed in DNA fragments shed by cancers into the bloodstream (i.e. cell-free DNA) can provide highly specific signals indicating cancer presence.
A randomised-controlled trial of 1-year adjuvant chemotherapy with oral tegafur-uracil versus surgery alone in stage II colon cancer: SACURA trial
- European journal of cancer (Oxford, England : 1990)
- Published over 2 years ago
- Discuss
Efficacy of adjuvant chemotherapy in patients with stage II colon cancer is still controversial. The SACURA trial is a randomised-controlled study evaluating the superiority of 1-year adjuvant treatment with oral tegafur-uracil (UFT) to surgery alone for stage II colon cancer.


text:
Wriddhiman Saha: from the sidelines to the starring role4 min read . Updated: 29 Mar 2017, 05:05 PM IST
Over the last 14 Test matches, Wriddhiman Saha emerged as the crisis man at No.6 for Indian Test team
Wriddhiman Saha was the fourth highest scorer among Indians, after Cheteshwar Pujara, K.L. Rahul and Ajinkya Rahane, in the just concluded four-match series against Australia that India won 2-1 on Tuesday.
This is no fluke. Over the last 14 Test matches, Saha has emerged as the crisis man at No.6. Though he scored only 31 runs in the first innings of the last Test at Dharamsala, his 96-run partnership with Ravindra Jadeja was critical in India getting a psychologically decisive lead.
"They (captain and coach) have a created a conducive environment," explains Saba Karim, who was part of the selection committee for four years. "They have made him feel that he is an important member of the side. The kind of space given by management has helped his game in the same way Pujara has been backed."
It has been a long waiting game for this unpretentious cricketer. Saha had to wait many years, for Deep Dasgupta's exit, to get into the Bengal Ranji Trophy team in 2007. By the time Saha could make his first-class debut in November 2007, Mahendra Singh Dhoni was already a Twenty20 World Cup-winning captain and a wicketkeeper-batsman for India.
"Dhoni's success at the international level was always a motivation for small-town boys. Saha's father Prasanta was a football goalkeeper in the 1970s and wanted his son to follow in his footsteps. But he chose cricket when he came to our coaching camp," recalls Jayanta Bhowmick, Saha's childhood coach from Siliguri.
Saha made his Test debut in February 2010 against South Africa as a specialist batsman (after Rohit Sharma suffered an injury on the morning of the match). Two years later, he got another chance in Adelaide (January 2012) when Dhoni was fined for slow over-rate and had to sit out. Almost three years later (December 2014), Saha played his third Test, again in Adelaide, after Dhoni retired from the longest format.
In the next eight Test matches Saha played, no one complained of missing Dhoni the wicketkeeper. But Dhoni the batsman was being missed as the Bengal wicketkeeper averaged around 21 with just two 50s.
It wasn't entirely surprising when Ravichandran Ashwin was promoted ahead of Saha at No.6 in the batting order on the West Indies tour in 2016. Even if it was largely a recognition of Ashwin's improved batting, it also reflected poorly on Saha, who had a better batting average (around 44) than Ashwin at the first-class level.
Adding insult to injury was the superb batting performance of Parthiv Patel (who scored 195 runs in four innings at an average of 65), who came as a replacement (when Saha got injured during the England Test series last year) after a hiatus of eight years.
Such was Patel's inspirational comeback that the Irani Trophy match between Ranji champions Gujarat (Patel was the captain) and Rest of India (ROI) in January was billed as a battle between two wicketkeepers.
Saha failed to open his account in the first innings. In the second, ROI needed 379 to win and had lost four wickets for 63 runs when Saha scored an unbeaten double hundred to take his team to victory.
Match won, the Test team selection formalities were completed and, more importantly, he got his batting position back against Bangladesh in the Hyderabad Test last month.
The 32-year-old scored his first Test ton on his comeback. The selection committee was unanimous in its choice for India's No.1 wicketkeeper and M.S.K. Prasad (himself a former India wicketkeeper) categorically stated that Saha had nothing to prove apart from his fitness.
"It's a great plus for the players," Saha had said after his first ton. "Because after an injury break, when one comes back, if you are clearly told that as and when you recover you will be back in the team, the individual gets more motivated and that helps in your performance."
Saha scored his second ton when Ranchi hosted its first-ever Test match against the Australians a fortnight ago. "He has always stood up when the team needs him and this game was no different," captain Virat Kohli said in his post-match conference in Ranchi.
"He's one guy who is always willing to do anything for the team. He has no problems in batting after Ashwin, before Ashwin, whenever we want him to do it. He plays any kind of role—positive, defensive, you know, whatever we ask him to do, he never says no," added Kohli.
Saha doesn't have a charismatic personality like his predecessor, Dhoni, but he is as valuable to the team. The rise of Dhoni from a small town like Ranchi is part of cricket folklore and in many ways Saha's journey isn't too different. Siliguri is more low-profile than Ranchi, which is almost 500km away from Saha's hometown.
Saha the batsman now looks more relaxed. "Initially, when I came into the Test team, I played those shots—the sweep and the shot over the top stepping out—hesitantly, but now I am 100% confident," he said in Ranchi.
Many observers believe he should not be compared with Dhoni—the former captain was a completely different package, and perhaps an aberration, like former Australian wicketkeeper Adam Gilchrist. It took Dhoni 40 matches to score three centuries; Saha has done it in 25.
If Saha keeps improving, matching Dhoni's career average (around 38) will not be difficult. That will be an accomplishment for a player who takes pride in calling himself a wicketkeeper first.
Vimal Kumar is the author of Sachin: Cricketer Of The Century and The Cricket Fanatic's Essential Guide. He tweets at @Vimalwa.
Click here to read the Mint ePaperMint is now on Telegram. Join Mint channel in your Telegram and stay updated with the latest business news.


text:
It's time to announce our latest Review of the Month, and I'm pleased to say that the £100 gift voucher is going to a veritable Lovehoney veteran. Sex Squid uploaded their first sex toy review in 2006, meaning they've been a proud part of our community for a decade. We're impressed!
Of course, we were also impressed by their wonderful review of the Vixen Mustang VixSkin Bright Realistic Dildo with Suction Cup 7 Inch, which includes a comparison to the Mustang Royale.
"I'm sure I'm not alone in finding that this joyous dick makes me want to burst into song! It's just so happy-looking. And as with my other Vixen dildos, it feels simply incredible. The VixSkin dual density silicone is remarkable. It's squishier than a real cock, but I don't see that as a bad thing. In fact, riding it anally, or when worn in a harness for pegging, it's lovely squashiness makes it more comfortable for anal than any other toy I've tried. When thrust deep and hard, the head can bump against your insides without causing you any discomfort, which means there's no need for your partner to pause. A submissive's dream then!" Read the full review here.
Congratulations Sex Squid, and enjoy your prize. Want in? Write your review now to be in with a chance to win next.


text:
Craig Pollock's 'Pure' company has paused its operations, the German website motorsport-total and journalists Dieter Rencken and Stefan Ziegler have revealed. Pollock, formerly the founder of Brackl...
Pollock, formerly the founder of Brackley based BAR and Jacques Villeneuve's manager, announced last year he intended to supply 'Propulsion Universelle et Recuperation d'Energie' (Pure)-branded engines to formula one customers for the 2014 V6 regulations.
The company set up camp at Toyota's Cologne headquarters earlier this year.
But the project, which also involves former Ferrari and FIA engine boss Gilles Simon, has hit a financial roadblock, the German-language report said.
A key investor pulled out a month ago, and now Pure will have to move out of Cologne, where it utilised office space, a workshop and engine test stands.
Simon informed Pure's partners and suppliers of the unfortunate development by email, explaining a financing problem.
Motorsport-total.com said Pollock confirmed the news.
"The situation is very simple," he is quoted as saying. "The investor is from the United States."
He went on to explain that Pure needs financing to come from Europe in order to satisfy Swiss tax rules.
"Until now we've been manufacturing parts and assembling engines in Cologne, but as of today, all of this has stopped," said Pollock.
He said he is expecting new European-based finance to be in place by "the end of the month".


text: As would be expected, fresh seafood is the main feature here, including grilled and steamed fish, cracked conch and other conch dishes, with lobster in season. Local specialties are fresh free-range mutton, turtle soup, peas and rice, and baked macaroni and cheese. You can find traditional Bahamian dishes at Ponderosa, Sheila's Fisherman's Lounge, and Silver Tails Fishing Lodge. The restaurants are not open regularly, except on mail-boat day and national holidays. However, you can always get a meal from places like Sheila's with prior notice and People-to-People volunteers who have personal relationships with regular boaters will often invite them to eat with their families when they're in the area.


text:
Category Archives: Bookkeeping
Success of Business Lies in Good Bookkeeping
Where does the success of each business lie? Many business owners mistakenly believe that once their businesses acquire a solid and wide market, and that their markets continue to patronize their services or products, their companies would naturally flourish. But this is not so. A good business should have all of these key factors- finance, … Continue reading


text:
Western dresses are comfortable for the individuals who wear it consistently, however, wearing a dress for a gathering is unique. You should know different tips and hacks to be agreeable in the dress and have a great time in the gathering alongside that being the sight to behold of the occasion.
Western dresses are presently in form and each young lady like them. They are in vogue, attractive and originator and give an astounding look to their identity. There are diverse stores that exhibit western dresses only for you. You can attempt a few and look perfect at any occasion, gathering or event. Wearing a western dress is no major ordeal yet there are sure things which you should know or take after while picking or wearing a western dress for parties. Dresses are intended to make you look and can rest easy and not to make you feel low. So it is critical to know how and what to wear while going out for a gathering particularly in western dresses.
The following are sure things which you should think about wearing western dresses for parties so you can have an extraordinary day ahead with you smart dress and look:
- The principal thing about wearing a western dress is picking the correct one. You need to pick a dress that runs well with the gathering. On the off chance that you host a themed gathering at that point, pick a dress in like manner.
- Try not to disregard the texture or other vital subtle elements of the dress since they are essential to make you look great.
- The texture that you wore ought to be agreeable and vaporous and you ought not to feel choked in the dress.
- Ensure that you pick the correct shading that matches your skin tone and make you look engaging and appealing and not dull and exhausting.
- You ought to be certain about what you are wearing so ensure that the dress is agreeable. It is for the most part on account of one piece dress.
- The dress ought to run with the gathering and you ought not to investigate or under dresses.
- Coordinate your dress with your footwear and accomplices to get a complimentary look and be the gorgeous sight of the occasion.
With the previously mentioned ways, it is conceivable to look perfect in a gathering and you should simply keep the previously mentioned focuses in your psyche. For purchasing western dresses for ladies visit istylefreak, the best web based shopping store for a wide range of western dresses at a spending benevolent cost and prevalent quality. Rest you can be guaranteed of different variables since they have a gigantic gathering and fluctuated plans only for you to look wonderful.
6183total visits,0visits today


text:
Book now
San Marco 2828/B 30124 Venice Italy
Area: --
View map
Book online or call +39 041 8624040
view info & map
Property Location
With a stay at this apartment in Venice (San Marco), you'll be a 3-minute walk from Academy Gallery and 12 minutes by foot from St. Mark's Basilica. This apartment is 0.6 mi (1 km) from Rialto Bridge and 0.3 mi (0.5 km) from Peggy Guggenheim Museum.
Make yourself comfortable in this apartment, featuring a kitchen with a refrigerator and an oven. A flat-screen television with digital programming provides entertainment, while complimentary wireless Internet access keeps you connected. Conveniences include a desk and a separate sitting area, and housekeeping is provided on a limited basis.


text:
Core Values
Because the Bible is the fully true Word of God
(2 Timothy 3:16), we will offer and require the study
of all 66 books of the Bible before graduation with a degree. We will seek to creatively integrate classical theological disciplines and ministry training by studying books of the Bible(i.e. Church History will begin with the Books of Acts and keep going; Pastoral Leadership will come through the study of the Pastoral Epistles; Systematic Theology will flow out of the study of the Pauline Epistles).
Because He is Lord (Philippians 2:11),
we will continually ask Jesus Christ to sit on the throne
of the seminary and on the throne of the lives of its faculty, administrators, and students for the
glory of God (1 Corinthians 10:31).
Because apart from Him we can do nothing (John 15:5),
we will continually seek to plug into the Vine Jesus Christ through yielding to Him in prayer. We will offer a unique emphasis on prayer including classes on prayer,
a school of prayer, prayer faculty, and multiple prayer opportunities in the life of the seminary.
Because the return of Christ awaits the evangelization of all people groups (Matthew 24:14), we will keep our eyes on the unreached peoples of the worldand train our students to have a heart for the fulfillment of the Great Commission (Matthew 28:18-20) by seeking to reach millionsof souls for Jesus Christ.
Because the local church is God's plan (Matthew 16:18),
we will be based in the local church and have a symbiotic relationship of service and training with local churches
and parachurch ministries.
Because we were created for community
(Genesis 1:26; Romans 12:5).
We will seek to build a campus-based fellowship
where the "one anothers" of Scripture are
lived out, where authenticity and accountability
are practiced, and where integrity is modeled and taught.
Because God has a huge heart for the poor
and overlooked (Matthew 25:31-46), we will strive
to motivate, equip, and train students to minister
to "the least of these" as a lifestyle.