text:
|Feb 20, 2013
Two-stage vectors deliver gene silencing therapy to tumors
|(Nanowerk News) Breast cancer patients with the so-called triple negative form of the disease have the lowest survival rate among all breast cancer patients, in large part because this type of cancer does not respond to most anti-cancer agents. Recent studies have shown, though, that triple negative breast cancers are susceptible to agents that interfere with DNA repair pathways, especially a protein known as ATM. Now, a research team from The Methodist Hospital Research has capitalized on this weakness with promising results.
|Haifa Shen and Mauro Ferrari led a team of investigators that created a two-stage delivery vehicle capable of ferrying an agent that targets this protein to triple negative breast tumors. When administered to mice bearing human breast tumors, the drug-bearing vector stopped the production of the ATM protein and greatly inhibited the growth of what otherwise is an aggressive cancer. The researchers published the results of their work in the journal Small ("Multistage Vectored siRNA Targeting Ataxia-Telangiectasia Mutated for Breast Cancer Therapy"). Dr. Ferrari is co-principal investigator of the Texas Center for Cancer Nanomedicine, one of nine Centers of Cancer Nanotechnology Excellence funded by the National Cancer Institute.
|To stop the production of ATM, the researchers created a short interfering RNA (siRNA) that targets the messenger RNA that codes for this protein. siRNA-based therapies have shown promise for treating cancer, but delivering them to tumors at therapeutic levels has proven challenging. Dr. Shen and Dr. Ferrari solved this problem using a two-stage delivery vehicle consisting of a nanoscale liposome and a disc-shaped, nanoporous silicon microparticle. The researchers use the liposome to encapsulate the siRNA agent and they take advantage of the biocompatible silicon microparticles to safely ferry the liposomes through the blood stream and deposit them just outside of the tumors.
|Because of their disc shape, the silicon microparticles accumulate efficiently in the blood vessels that surround tumors. In earlier work ("Discoidal Porous Silicon Particles: Fabrication and Biodistribution in Breast Cancer Bearing Mice"), Dr. Ferrari and his Texas Center for Cancer Nanomedicine colleague Paulo Decuzzi had shown that approximately between six and 10 percent of an injected dose of silicon microparticles accumulate in the tumor vasculature compared to less than 0.1 percent of conventionally administered drug. Once the microparticles settle around the tumor, they gradually degrade into non-toxic materials and slowly release the liposomes. The liposomes then migrate into the tumors, where they are taken up by cancer cells and release their siRNA payload.
|While experiments in tumor bearing mice showed that this two-stage delivery system was effective at suppressing tumor growth, they also demonstrated that it did not trigger a potentially dangerous immune response that is often seen with siRNA therapies. Additionally, during the four-week experiments, body weight, blood chemistry, and tissue histology did not reveal significant toxicities which are often associated with chemotherapies.
|Source: National Cancer Institute
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text:
LWP::Authen::OAuth2::ServiceProvider::Google - Access Google OAuth2 APIs
Version 0.02
See LWP::Authen::OAuth2 for basic usage. The one general note is that
scope is
scope is optional in the specification, but required for Google. Beyond that Google supports many client types, and their behavior varies widely.
See https://developers.google.com/accounts/docs/OAuth2 for Google's own documentation. The documentation here is a Cliff Notes version of that, so look there for any necessary clarification.
Before you can use OAuth 2 with Google you need to register yourself as a client. For that, go to https://code.google.com/apis/console. Follow their directions to create a project, choose your
flow (which is called your
client_type in this document - look ahead for advice on available types), and then you'll be given a
client_id and
client_secret. If you're in the Login, WebServer or Client client types you'll also need to register a
redirect_uri with them, which will need to be an
https://... URL under your control.
At that point you have all of the facts that you need to use this module. Be sure to keep your
client_secret secret - if someone else gets it and starts abusing it, Google reserves the right to block you.
This module only handles the authorization step, after which it is up to you to figure out how to use whatever API you want to access.
Google offers many client types. Here is the status of each one in this module:
- Login
This is for applications that want to let Google manage their logins. See https://developers.google.com/accounts/docs/OAuth2Login for Google's documentation.
This is not yet supported, and would require the use of JSON Web Tokens to support.
- Web Server Application
This is intended for applications running on web servers, with the user sitting behind a browser interacting with you. See https://developers.google.com/accounts/docs/OAuth2WebServer for Google's documentation.
It can be specified in the constructor with:
client_type => "web server",
however that is not necessary since it is also the assumed default if no client_type is specified.
After registering yourself as a client with Google, you will need to specify the
redirect_urias an https URL under your control. If you just need this for one or two accounts there is no need to actually build anything at that URL - just go through the authorization as those accounts and grab your
codefrom the URL. If you will support many, making that URL useful is your responsibility.
With this client type you are not guaranteed a refresh token, so the constructor does not require
client_secret. (Passing them there is still likely to be convenient for you.) However there are several optional arguments available to
$oauth2->authorization_url(...)that are worth taking note of:
access_type => "offline",to
$oauth2-request_tokens(...)> to request offline access. This means that you get a
refresh_tokenwhich can be used to refresh the access token without help from the user. The intent of this option is to support things like software that delays posting a blog entry until a particular time.
In light testing this did not work for me until I passed the next argument, but then it worked perfectly.
approval_prompt => "force",to
$oauth2-request_tokens(...)> to force the user to see the approval screen. The default behavior without this is that the user sees the approval screen the first time through, and on subsequent times just gets an immediate redirect.
If you think you know who the user is, you can pass an email in this parameter to let Google know which account you are trying to access. Google thinks this may be helpful if someone is logged into multiple accounts at the same time.
- Client-side Application
This client type is only for JavaScript applications. See https://developers.google.com/accounts/docs/OAuth2UserAgent for Google's documentation.
This is not supported since Perl is not JavaScript.
- Installed Application
This client type is for applications that run on the user's machine, which can control a browser. See https://developers.google.com/accounts/docs/OAuth2InstalledApp for Google's documentation.
It can be specified in the constructor with:
client_type => "web server",
On the first time it is the client's responsibility to open a browser and send the user to
$oauth2-authorization_url(...)>. If you pass in
redirect_uri => "http://localhost:$port",then your application is expected to be listening on that port. If you instead pass in
redirect_uri => "urn:ietf:wg:oauth:2.0:oob",then the code you need will be in the
titleinside of the page the browser is redirected to, and you'll need to grab it from there.
The returned tokens always give you a refresh token, so you only have to go through this once per user.
The only special authorization argument is
login_hint, which means the same thing that it does for webserver applications.
- Devices
This client_type is for applications that run on the user's machine, which do not control a browser. See https://developers.google.com/accounts/docs/OAuth2ForDevices for Google's documentation.
This client_type is not supported because I have not yet thought through how to handle the required polling step of setting up permissions.
- Service Account
This client_type is for applications that login to the developer's account using the developer's credentials. See https://developers.google.com/accounts/docs/OAuth2ServiceAccount for Google's documentation.
This is not yet supported, and would require the use of JSON Web Tokens to support.
Ben Tilly,
<btilly at gmail.com>
The main bug is that out of 6 client types, 5 of which could reasonably be supported, only two are so far.
Please report any bugs or feature requests to
bug-lwp-authen-oauth2 at rt.cpan.org, or through the web interface at http://rt.cpan.org/NoAuth/ReportBug.html?Queue=LWP-Authen-OAuth2. I will be notified, and then you'll automatically be notified of progress on your bug as I make changes.
You can find documentation for this module with the perldoc command.
perldoc LWP::Authen::OAuth2::ServiceProvider
You can also look for information at:
- Github (submit patches here)
- RT: CPAN's request tracker (report bugs here)
- AnnoCPAN: Annotated CPAN documentation
- CPAN Ratings
Thanks to Rent.com for their generous support in letting me develop and release this module. My thanks also to Nick Wellnhofer <email@example.com> for Net::Google::Analytics::OAuth2 which was very enlightening while I was trying to figure out the details of how to connect to Google with OAuth2.
Copyright 2013 Rent.com.
This program is free software; you can redistribute it and/or modify it under the terms of the the Artistic License (2.0). You may obtain a copy of the full license at:
Any use, modification, and distribution of the Standard or Modified Versions is governed by this Artistic License. By using, modifying or distributing the Package, you accept this license. Do not use, modify, or distribute the Package, if you do not accept this license.
If your Modified Version has been derived from a Modified Version made by someone other than you, you are nevertheless required to ensure that your Modified Version complies with the requirements of this license.
This license does not grant you the right to use any trademark, service mark, tradename, or logo of the Copyright Holder.
This license includes the non-exclusive, worldwide, free-of-charge patent license to make, have made, use, offer to sell, sell, import and otherwise transfer the Package with respect to any patent claims licensable by the Copyright Holder that are necessarily infringed by the Package. If you institute patent litigation (including a cross-claim or counterclaim) against any party alleging that the Package constitutes direct or contributory patent infringement, then this Artistic License to you shall terminate on the date that such litigation is filed.
Disclaimer of Warranty: THE PACKAGE IS PROVIDED BY THE COPYRIGHT HOLDER AND CONTRIBUTORS "AS IS' AND WITHOUT ANY EXPRESS OR IMPLIED WARRANTIES. THE IMPLIED WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, OR NON-INFRINGEMENT ARE DISCLAIMED TO THE EXTENT PERMITTED BY YOUR LOCAL LAW. UNLESS REQUIRED BY LAW, NO COPYRIGHT HOLDER OR CONTRIBUTOR WILL BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, OR CONSEQUENTIAL DAMAGES ARISING IN ANY WAY OUT OF THE USE OF THE PACKAGE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.


text:
The debt ceiling is expected to be reached, officially, on Monday, December 31st, when the national debt reaches $16.4 trillion. Unofficially, with various "extraordinary measures" employed, the Treasury won't bump into the real limit until early February.
Those measures will give the Treasury some $200 billion in "headroom" and since the government is borrowing $100 billion every month, the math is easy. The question then becomes: what happens next?
President Obama has demanded that any discussion about the debt ceiling be deferred until after the fiscal cliff crisis has been resolved. He frankly would prefer that the issue go away entirely, and has offered to take on the responsibility of raising it unilaterally, effectively removing such responsibility from Congress altogether.
Using a measure first proposed by Senate Minority Leader Mitch McConnell, the White House would request a debt ceiling increase from the Congress and the Congress would then just approve it. If the Congress fails to approve it, the president could then veto the disapproval, unless Congress overrides his veto – a highly unlikely outcome. In simple terms, Obama would be given a credit card with limits that can be raised with a phone call.
This, the president asserts, would give great comfort and assurance to the bond market that the government would never default on its debt, thus keeping interest rates low. Such a measure would also remove the debt ceiling discussion as a hammer by members of congress who want spending cuts from the White House.
All of this is just a charade, according to Peter Schiff, the CEO of Euro Pacific Capital and supporter of limited government. He wrote that "these debates have become nothing more than exercises in feigned outrage. If Congress wants to control the debt, let them do so. If they don't care, just continue on the current path."
Schiff has found agreement from unlikely places. Jay Carney, in a White House press conference earlier this month, said that all raising the debt ceiling does is assure debt holders that they will get paid, or at least have their maturing debt rolled over without incident.
And Isabel Sawhill, an economist at the liberal think-tank Brookings Institute, said:
Those who believe that a refusal to raise the debt ceiling will somehow put limits on spending and shrink the size of government are confusing the need to pay obligations already incurred by Congress with the need to rein in future expenses.
Simply put, using the debt ceiling as a hammer is ineffective at restraining the growth of government as it only allows the government to pay for bills the Congress has already run up. It is backward looking rather than forward looking. Sawhill added:
Spending restraint is needed…and is the right way to fix rising levels of debt. The debt ceiling itself is an anachronism. As Alan Greenspan once put it, we don't need both suspenders and belts.
The debt ceiling law was passed in 1917 in response to fiscal conservatives' demands that the newly created Federal Reserve be limited in how much government debt it was allowed to purchase. By opening the door by just an inch, the Congress allowed the Fed, over time, through the charade of debates over the debt ceiling, to own vastly larger amounts of government debt. Since 1917 there have been 91 debt ceiling increases, and government spending has continued to increase apace.
Schiff has seen through the charade and thinks the only benefit to it would be to alert taxpayers that government spending continues out of control.
The last two debt ceiling debates illustrated the ineffectiveness of them as a tool to bring spending down. In January, 1996, the House refused to increase the debt ceiling and the government had to stop all spending, for just a few days. When Social Security checks were threatened, President Clinton's popularity rose while that of the House plummeted. The House capitulated and the Treasury got its new debt ceiling.
In the summer of 2011 a similar debt ceiling debate raged, which ended with the Budget Control Act of 2011 which allowed the debt ceiling to be raised by the Treasury department without further input from Congress in exchange for will-of-the-wisp promises of spending cuts sometime in the future.
No matter how the current fiscal cliff negotiations turn out, there's another debate waiting to be joined, with a similar outcome likely. Instead of using the debt ceiling as a jousting lance, Congress should attack the spending issue frontally. If it doesn't, the bond market eventually will do it for them.


text:
Book your Caribbean getaway
Escape to picturesque Turks and Caicos and combine an award-winning flight with a great value hotel.
Escape to picturesque Turks and Caicos and combine an award-winning flight with a great value hotel.
A beautiful British Crown colony, that consists of 40 islands and cays, eight of which are inhabited. With miles of unspoilt coral reefs and magnificent natural wonders - from the breathtaking cliffs of Mudjidin Beach to the spectacular limestone caves of Middle Caicos.
Absorb the splendour and tranquillity of Turks and Caicos - where each island has its own individual character. Providenciales, more commonly known as 'Provo' is the most developed island and where you'll find our handpicked range of hotels. Combine pure escapism with unforgettable adventures and wonderful attractions that have been carefully preserved to maintain their original glory. Laze on beautiful Grace Beach, which was ranked as "Best Beach" by Conde Nast magazine or see the lagoons and stalagmites of Conch Bar Caves National Park. Hike the Crossing Place Trail and take in some of the islands finest views or head to the smaller cays for incredible bird watching.
Book flight + hotel together and save
BA Star Rating
TripAdvisor rating
1096 reviews
BA Star Rating
TripAdvisor rating
13387 reviews
Find a British Airways flight for less, we'll refund the difference.
Fly with British Airways and enjoy award-winning service and excellent value for money.
Economy prices include:


text:
Liberty Barbecue
Top tags:
For your safety and ours, please note that there will be an enforced hour and a half time limit placed on ALL diners. No one with a fever or symptoms of COVID-19, or with known exposure in the prior 14 days, is permitted in the restaurant. We ask everyone to maintain SOCIAL DISTANCING of at least 6 feet at all times. Guests are responsible for compliance with the VDH and CDC guidelines as it relates to mask usage throughout your visit with the exception of while eating or drinking. Thank You
Liberty strung lights outside and spread tables across the parking lot to create a festive but safe-feeling vibe, with music playing and dogs enjoying the evening with their owners. The food was terrific, lots of beer and wine choices, and servers were friendly and efficient. We will be back!
Great outdoor seating area
Great patio for socially distanced dining.
It was great as usual. Glad to eat at their facility again. We've done a lot of take out from them during the pandemic. We even had them cater our Friendsgiving party last fall right before Thanksgiving and we also had a turked from here on Thanksgiving.
It was good overall. I would recommend it to a friend.
This is my FAVORITE BBQ place in the DMV! The food is amazing, the staff is friendly, and the ambiance is fun and lends well to social distancing.
My husband loved the pulled pork. We had a great lunch
Great to be able to sit outside! Nice days! Shaded seating!! Great service. Will be back!!
Slow service but food is good for what you're getting.
I wanted to love it, but it was just ok. We got ribeyes, and both were barely luke warm...as in the butter on top didn't melt at all. My cut had significantly more fat than expected as well (the size of my fist). The service was good though.
First time. I love the outdoor patio...and the cheese and chips.
We ordered a three meat plate to try the varied meats offered-all of it was great and delicious! we will be visiting again and trying other menu items.
Liberty Barbecue is one of my favorite restaurants. I love the brisket. The service is always good and they are very welcoming and accomodating. I give this a 5 for indoor, outdoor and drive-up service.
Had a family of four, to include two picky eaters. It was a great Father's Day there! Food and service were great!
Food was OK...lacked a sauce that wasn't completely vinegar based. I would have liked something a little sweeter and/or spicier. Meat was tasty and tender.
Excellent BBQ, mac-n-cheese and fried chicken. Will be adding this to our go-to restaurant list.
Glad that Liberty is open again for outdoor and indoor eating! As always the food (salmon salad) and service was great.
Father's Day!!! Staff was super friendly!! Food delightful.
Our favorite barbeque place in the DMV. Awesome corn muffins too!
The food was good but I've had better bbq. The margaritas were really good and the service was awesome!
We were seated on the outdoor patio due to COVID-19 regulation. They were at capacity but maintained excellent service. It's a very casual style with food being served in throw away containers. I had ribs with sides of potatoes salad and brussel sprouts and my adult son had pulled bbq chicken sandwich. There was nothing exceptional about any of it. So we were a bit disappointed. It's not likely that we will return.
As always the service and the food was great especially the salmon salad!
Delicious meat, well smoked, and great sides. for the money, though, I wish the quantity was more. So while super delicious, we found the portions on the small side. For reference, we got the 3 meat platter w/ 2 sides.
Seated outdoors due to COVID restrictions, we felt welcomed and appreciated. Umbrellas could have been placed a little better to keep the sun out of our eyes but that's a minor point.
Food was excellent. I had ribs and brisket while my wife had pulled chicken and pork. Portions were generous and sides were tasty. Limited dessert menu but the chocolate cream pie was great.
Great to be dining out again. Liberty Barbecue was just what we needed.
Good portions, good service, nice patio. We will definitely return.
Excellent service and food
Excellent food, great service and great margaritas! Its a winner in Falla Church.
Brussel sprouts and margaritas are fantastic here! Staff is friendly and accommodating. Thanks for a nice dinner!!
Maybe it was an off night. Beef was very fatty and the chicken was not pulled it was chopped, big difference. Also they still kill the baked beans with caraway flavor. The brussel sprout and cauliflower sides are great and good beer list
While we enjoyed our meal, the only negative thing that I can say is that our hostess made our guest wait over 15 minutes to join us at the table. It could be that she was having a bad day which took away from our experience.
Liberty BBQ delivered the goods. Went with a group of 8 and ordered a couple of the platters. We had plenty of food and it was delicious. Especially enjoyed the brisked and ribs, and also the cole slaw..
On top of the quality of the food, the service was great and our round table allowed for all my guests to enjoy a group conversation. We'll be back..
Smoked wings were awesome, but they brought our entrees oust right on top. Great Q but a bit pricy, for example 4.50 for a cup of tasty Brussels sprouts....
Was a little noisy but not bad, great service, the food left a lot to be desired, way too much pepper on the meat, and the bbq beans were really tangy
We went for brunch to celebrate my husband's birthday - we had a rather large group and this was the perfect spot to gather!
This was a great find. The weekend buffet was wonderful -- the usual suspects plus mussels, salmon and barbecue! Plate by plate I ate every dish in order, until I had to make choices due to being full. The biscuits and gravy are a stand-out, as were the salmon and mussels (total surprise). As were the brownies. I passed on the waffles and challah french toast and have regretted it all week! I expected the place to be packed, but it was not! We were seated promptly despite the fact that only 2 of us showed up (at first). The others found their way to us. Our waitress went above and beyond, handling the 11 of us with courtesy and confidence. If I had my own business, I would hire her -- she is that type of person who is always competent and confident, and creates a wonderful impression. I will go back here again and again, maybe not always picking up a check for 11, but definitely for Happy Hours etc.
We love Liberty BBQ. Food and service are great. Deviled egg appetizer, fried chicken, and smoked meats are all excellent. Unfortunately, they never have the sausage in stock even though it's always on the menu. What's up with that?
I have been telling everybody about our brunch at Liberty BBQ. My husband and I took our three boys for brunch on Sunday. We were all happy about the variety of food and every single item was just fantastic. It was a little quiet when we got there (11:30) but that just meant no waiting in line for us! We all left there stuffed. We will go back for sure.
Our second time. Food good! Band fun!
I happened to be driving by, and made the connection between Liberty Tavern and Liberty BBQ, so figured I needed to check this place out! I took my parents there for my mom's birthday -- she loves BBQ. We had a great time; our waiter was very attentive, especially to my food allergy, which I always appreciate. I'm also glad we went during a time that wasn't super-crowded. We enjoyed it!
We tried the ribs, pulled pork and beef brisket. They all get a home run in our book, and we love BBQ! The variety of BBQ sauce from vinegar-based to sweet, tomato-based made us happy too. The potato salad was a bit salty and needed more umph for my taste. The brisket Navy beans were good. In the future I would order their 3-cheese mac'n cheese and perhaps one of their more unique sides (Brussel sprouts or cauliflower?).
The cocktail menu looked intriguing, even if you wanted a mocktail adaptation.
Liberty Barbecue offers takeaway which you can order by calling the restaurant at (703) 237-8227.
Liberty Barbecue is rated 4.5 stars by 52 OpenTable diners.
Yes, you can generally book this restaurant by choosing the date, time and party size on OpenTable. Due to local restrictions, this restaurant may not be accepting reservations at the moment.


text:
Five months from now, Chael Sonnen (27-12-1 MMA, 6-5 UFC) will fight for the UFC's light heavyweight title.
He hasn't registered a 205-pound win in the octagon since 2006, and he was soundly defeated by UFC middleweight champion Anderson Silva in his most recent appearance. So why did UFC light-heavyweight champion Jon Jones (17-1 MMA, 11-1 UFC) agree to coach opposite Sonnen on "The Ultimate Fighter 17" and ultimately face him in the octagon?
"Bones" said it was an easy choice. This is his chance to silence the trashtalking master by beating him down in a cage.
"Chael definitely doesn't deserve to fight me, and everybody sees that," Jones told MMAjunkie.com (www.mmajunkie.com). "As long as people see that at the end of the day, I'm happy with that. But at the same time, a lot of people have said, 'Why not be the guy to shut him up once and for all? Why not be the guy to make his words very irrelevant once and for all – put a stamp on what Anderson did to him.' That's what I'm going to try to do."
Sonnen, of course, has in recent years established himself as one of the sport's biggest superstars by not only beating the likes of Michael Bisping, Nate Marquardt, Yushin Okami and Brian Stann but also serving up some of the most memorable trashtalk in MMA history. For the past few years, Silva had been Sonnen's primary target, but after falling short in a July rematch with "The Spider," the self-described "gangster from West Linn, Oregon" turned his attention to Jones.
Sonnen often refers to the champ as "Little J.J." and frequently offers wisecracks related to Jones' May arrest on a misdemeanor DWI charge. Of course, Sonnen was willing to back up the talk when he accepted a proposed UFC 151 with Jones that the champ ultimately turned down, resulting in the cancellation of the event.
In typical Sonnen fashion, he responded by offering up "The Jon Jones" at his Oregon restaurant Mean Street Pizza. "Loaded with chicken and full of cheese," the menu read. "Comes with a six-pack of beer."
Jones has endured previous run-ins with the likes of Quinton "Rampage" Jackson and Rashad Evans, and he admits their verbal barbs often affected him personally. This time around, however, he insists Sonnen's quips are more entertaining than hurtful.
"Earlier in my career, I would have taken things a lot more to heart, I think," Jones said. "But I've faced so much adversity in such a short amount of time, it's just really making the game so easy. I'm facing all the drama, all the controversy, I'm facing it at such an early stage, there's going to be nothing left for me sooner or later."
Still, if Sonnen's barbs didn't bother Jones, then why take the fight? After all, Jones has defeated former UFC champions in each of his past five appearances, so facing a middleweight coming off of a loss hardly seems necessary.
Jones said it was the challenge of taking on the sport's most-revered trashtalker and doing so in the pressure cooker that is "The Ultimate Fighter."
"I'm doing what most people wouldn't dare to do: face this guy's main gift while being around him all day, every day for six weeks," Jones said. "Most people can't stand to have Chael be interviewed about them. Most people want Chael on their side. Chael can be intimidating when it comes to insults and selling a fight. But I'm doing what most people would think I'm crazy to do. I'm going to be around you all day, every day. Let's hear what you got.
"I'm a winner. I believe I'm a winner. When you're a winner, why should you be afraid of anybody's gift? He's got the gift of gab. So what? I believe me just simply being myself will prevail. I'll out-do any tactics or insult that Chael has for me, and at the end of the day, I think I'll win because I'm confident in being a good person."
Jones, Sonnen and a cast of prospective UFC fighters are currently in Las Vegas filming "TUF 17," which debuts in January on FX. The two coaches then face off on April 27 at a UFC pay-per-view event that is expected to take place in New Jersey.
Sonnen's wit is unquestionably going to play a major role in not only the reality competition series but also the build-up to their championship fight, and the tension is expected to build. Additionally, both Jones and Sonnen have proven polarizing figures in their UFC careers and seem to strike major chords with fans who either love or hate both the dominant champion and the brash challenger. So while the fight between the two doesn't necessarily make a ton of sense in a traditional rankings manner, most fans seem to a have vested interest in watching one of the two men get his ass kicked.
Jones said it's that fan emotion that ultimately swayed him toward taking the fight.
"First and foremost, it was about giving people what they wanted to see," Jones said. "Chael Sonnen is somebody that I respect because of his past performances, but he doesn't intimidate me at all. I have no doubt in my mind that I'll beat Chael. But this is a chance to give the fans what they want, to show who I am as a person for 'TUF' and to let Chael show who he is as a person and to just entertain the fans – to be that guy.
"I'm confident. I have no worries. People will get to see who I am, and that's awesome. In the cage, that speaks for itself. Outside of the cage, I'm excited to let who I am speak for itself, too."
For more on "The Ultimate Fighter 17," as well as "UFC in Newark: Jones vs. Sonnen," stay tuned to the UFC Rumors section of the site.
(Pictured: Jon Jones)


text:
WINNIPEG, Manitoba — The city of Winnipeg has three Catholic cathedrals with artistic gems that reflect Manitoba's rich religious and cultural heritage.
St. Mary's Cathedral of the Archdiocese of Winnipeg, which serves Latin-rite Catholics — primarily English-speaking — is situated near the Winnipeg Convention Centre, in the city center. The building was consecrated late in the 19th century, but its exterior belies some of the contemporary works inside, such as the art over the 21st-century baptismal font at the back of the church. The glass pane above the font depicts the baptism of Jesus and reflects the nave.
(In the interest of full disclosure, photos for this blog were taken with a point-and-shoot camera, not the normal equipment used by CNS.)
The Archdiocese of Saint-Boniface serves the area's French-speaking Catholics. When people think of this cathedral, they often picture the impressive French-Romanesque façade. But inside the shell of the early 19th-century structure is a modern church. The artwork is stunning and reflects the liturgical, cultural and historical roots of the area, dating back to native peoples and French explorers.
The 1970s cathedral, including its windows, was designed by Etienne Gaboury. He used modern images for his work, including the windows depicting the Stations of the Cross, which form most of the nave's side walls. His stained-glass Last Supper, over the entrance to the nave, is a three-dimensional phenomenon.
Winnipeg is also home to the Ukrainian Catholic Church's Archeparchy, the term for an Eastern Catholic archdiocese. The Cathedral of St. Volodymyr and Olha is full of Eastern symbols and icons. Its stained-glass windows were designed by Dutch-Canadian artist Leo Mol.
But for many visitors, perhaps the most impressive church art will be the iconostasis, the ornate gold screen in front of the altar.


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I am currently enrolled in an online course for AP Computer Science, and it is becoming confusing without a teacher to ask questions to. I am having some difficulty with inheritance methods. In this course I am using BlueJ as a compiler and the textbook is "Java Au Naturel" by William C. Jones. My assignment that I can't finish is as follows:
Exercise 1.12* Write a StarTurtle class with two instance methods: One draws a five- point star (hint: turn 144 degrees) and one draws a six-point star (two overlapping equilateral triangles with symmetry). Make them 60 pixels per line segment. // I've done this part, it was not a problem at all, 1.13 is the difficulty.
Exercise 1.13* Write an application program that uses a StarTurtle object, as defined in the preceding exercise, to make an interesting drawing with at least five stars in it.
The wording in the book is a little confusing about inheritance. In BlueJ I have three classes, Turtle, TurtleT, and the one that I use to program. I quite honestly have no idea where I go to do inheritance. Do I make another class? Or another method? Just lost.
Here is what I had for 1.12 if it helps:
public class StarTurtle extends Turtle
// Draw a 5 pointed star, 60 pixels per line, 144 degree turn
// Draw a 6 pointed star. (Two equilateral triangles)
public void make5star() {
star.paint (144, 60); // All 5 of these create a side of the star
star.paint (144, 60); //
star.paint (144, 60); //
star.paint (144, 60); //
star.paint (144, 60); // end star
} // this right-brace marks the end of the main method
public void make6star() {
star6.move (-180, 200); //Gets away from the first star
star6.paint (120, 60);
star6.paint (120, 60);
star6.paint (120, 60); //First triangle complete
star6.move (90, 30); //Move away from triangle
star6.paint (90, 60);
star6.paint (120, 60);
star6.paint (120, 60); //Second triangle complete
} // this right-brace marks the end of the main method


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OHCHR in Togo2014-20172010-20112008-20092006-2007
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The OHCHR Country Office in Togo was established in November 2006 to help build national capacities to protect human rights. It assists the Government in designing policies to implement the 22 commitments on democracy and human rights undertaken with the European Union in April 2004 and the recommendations of the UN mission of inquiry issued in 2005. As it moves into the second year of its operation, the Office will focus on the administration of justice and rule of law, human rights education, and the integration of human rights into the activities of the UN Country Team.
The political parties and the Government of Togo signed a Global and Political Agreement, brokered by President Blaise Compaoré of Burkina-Faso, on 20 August 2006, and established a follow-up committee. The Agreement proposes the creation of two commissions that will be responsible for establishing the truth on past postelectoral crimes and human rights violations, and for promoting reconciliation. The Country Office will provide technical, neutral support for the process.
The UN Special Rapporteur on torture visited Togo in April 2007 at the invitation of the Government, illustrating the Government's willingness to open itself up to independent and objective scrutiny of its human rights situation. The Special Rapporteur commended the Government for the progressive implementation of the undertakings with the European Union, of the UN mission's recommendations, and the Global Political Accord. At the same time, he recommended that the Government take further measures against impunity by establishing an effective and independent mechanism to investigate incidents of torture; continue its efforts to improve detention conditions; support the National Human Rights Commission in its efforts to become an effective player in the fight against torture; establish effective mechanisms to enforce the prohibition of violence against women; ratify the Optional Protocol to the Convention Against Torture; and establish effective national mechanisms to carry out unannounced visits to all places of detention.
Since November 2006, the Office has organized and supported training for judges, the media, the military, police and civil society. The Office is viewed as an impartial arbiter and is respected for its courage in taking the lead on such sensitive issues as those related to impunity,which are now openly discussed. The Office has built constructive and dynamic relationships with all national actors. It monitored the human rights situation throughout the country before, during and after the parliamentary elections that took place on 14 October 2007. Five temporary sub-offices opened in Aneho, Atakpame, Kara, Mango and Sokode monitored the human rights situation and conducted sensitization programmes in each area.
The Office will support the establishment and functioning of justice and accountability mechanisms, in accordance with international human rights standards, to monitor, investigate and redress violations of civil, political, economic, social and cultural rights.
Building on experiences from Sierra Leone, Burundi, Liberia and elsewhere, the Office will advise and support the Government in establishing the two accountability mechanisms envisaged under the Global Political Agreement. The Office will also launch a human rights education campaign and a national campaign against impunity.
OHCHR will provide technical assistance and financial support to the National Human Rights Commission and NGOs. Joint monitoring, reporting and advocacy activities will be undertaken, including assistance to the Ministry of Human Rights in implementing the national human rights action plan adopted in May 2007 and working with the Ministry of Justice on the Modernization-of- Justice Programme. Human rights training for NGOs, the security forces, the judiciary, lawyers, prison officials and the media will help bridge knowledge and capacity gaps in national human rights monitoring, reporting and advocacy.
The Office will develop an advocacy strategy and provide technical advice to the Government to ensure that national legislation complies with international human rights standards. This support, especially in the field of women's rights and gender-based violence, prevention against torture and discrimination will result in legislative and policy changes in compliance with Togo's international treaty obligations.
OHCHR will advocate for the implementation of recommendations of the Committee against Torture (CAT), the Committee on the Rights of the Child (CRC) and the report of the Special Rapporteur on torture. Support given to the Inter-ministerial Committee on Reporting will result in the development of a national framework and plan of action to implement the recommendations and to ratify standards related to migration, persons with disabilities, and the optional protocols to the Convention against Torture and Other Cruel Inhuman or Degrading Treatment or Punishment, the Convention on the Elimination of All Forms of Discrimination Against Women and the Convention on the Rights of Persons with Disabilities. The Office will also continue to provide its support to Special Rapporteurs who visit the country.
The Office will continue to work with the UN Country Team, particularly the UN Governance Working Group, to encourage joint activities on human rights themes, including activities commemorating the 60th anniversary of the Universal Declaration of Human Rights, and follow-up on concluding observations of the CAT and the CRC. Training sessions on international human rights mechanisms and standards and on rights-based approaches will be intensified to facilitate coordination with the humanitarian and development components of the UNDAF. The Office will also continue its ongoing joint action with UNHCR to protect returnees and will develop other joint activities with UNICEF on human trafficking and slavery-like practices. In addition, it will work with the United Nations Regional Centre for Peace and Disarmament in Africa (UNREC) and UNDP on conflict prevention and resolution.
OHCHR's visibility and presence outside the capital, Lomé, is of strategic importance in its next phase to help bring the human rights message closer to the people and facilitate closer monitoring of the human rights situation and public reporting. Thus the Office plans to open two field offices, in Sokode (centre) and Dapaong (north), in 2008.
Field Operations and Technical Cooperation
Division (FOTCD)
Contact in Geneva, Switzerland.
Africa Branch
Tel. +41 22 917 9220
African Commission on Human and Peoples' Rights
African Court of Human Rights
Geneva Conventions
ILO Conventions
Organisation Internationale de la Francophonie
National Human Rights Commission
Refugee Conventions


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Tyler sits down with Morningstar's Heather Brilliant to find out how they picked Canadian Pacific's Hunter Harrison as the top CEO of 2013.
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A period romantic drama set in the 1980s, Undiporaadhey is inspired by real-life incidents. The film follows a young girl and boy who meet and fall in love during their college days, and an unexpected turn of events that changes their lives forever.
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Quantitative determination of biogenic volatile organic compounds in the atmosphere using proton-transfer reaction linear ion trap mass spectrometry. Analytical Chemistry. 82(19):7952-7957.. 2010.
Ubiquitous influence of wildfire emissions and secondary organic aerosol on summertime atmospheric aerosol in the forested Great Lakes region. Atmospheric Chemistry and Physics. 18(5):3701-3715.. 2018.


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In the pornified music world populated by churned-out female pop stars pumping and grinding to a sexualised script, cavorting semi-naked and presented as sexually insatiable, we see Miley Cyrus simulating sex acts while denuded of real sexuality.
While many around the world condemned what was seen as an overtly sexualised performance at the recent MTV music awards, her crotch-centred routine – which included rubbing the groins of herself and Robin Thicke with a giant hand possibly stolen from a Coles "down, down, prices are down" ad – was one of the most desexed stage performances I have seen.
Miley Cyrus is a business. Her mostly male management would have scripted every plastic fake sex move. In an industry dominated by men, Cyrus thrusted and writhed because these same men thought there would be money in it.
The view of some young people whose thoughts I sought in schools last week was that it was less an expression of sexuality than of ugliness. For them, Cyrus' performance represented a distorted version of female sexuality. And if Cyrus' management thought the act would shore up her fan base, they have misjudged.
Almost without exception, the girls groaned and rolled their eyes when I asked them about it. Grace, 13, says: "The performance portrayed a negative image of women."
Alex, 13, drew attention to the shaping of boys' thinking. "It shows boys that's how we are, our image."
Megan, 12: "She thinks it's cool, she'll attract more people, but she hasn't."
Emma, 11: "I felt overexposed to something I shouldn't have watched."
These girls noted that the women on stage wore less clothing than the men. They wanted to know why this differential nakedness was acceptable. It troubled them that Robin Thicke – whose Blurred Lines song has been condemned as justifying non-consensual sex, is almost twice Cyrus' age. (Defined Lines, a parody by three female University of Auckland students sending up Thicke's song, was temporarily removed from YouTube for displaying sexually explicit content, while his clip containing topless women can still be viewed in full online.)
X-rated artificial sex routines have become banal. The girls expressed a desire to enjoy female talent free of predictable objectified routines. They want to see an emphasis on the song more than the body.
Lady Gaga pulls a machinegun out of her vagina, Katy Perry shoots whipped cream from her breasts and Rihanna offers S&M and bondage themes. It may be porny, but it's far from erotic.
And, of course, there is a contrast in the judgment afforded to women compared with men. Men are so often let off the hook. US rap artist Tyler, The Creator, who sings about rape being fun, raping a pregnant woman and calling it a three-way and raping female corpses, was given a visa to perform his live misogyny at "all ages" Australian concerts recently.
Flo Rida's Can't Believe It, at No. 7 on the top-40 charts, also enforces the female-artist-as-porn-performer theme. The song opens with, "Damn, that white girl got some ass", and the video features objectified, headless women with oversize backsides. Women are depicted visually as ice-cream and in porn-style poses.
Justin Timberlake's Tunnel Vision clip has him in a suit surrounded by naked women whose sole purpose is to writhe around him. It is a complete double standard. We don't see male artists gyrating their bums before the cameras.
The female students I spent time with wanted to see more female performers who defied limited visions of womanhood. They saw Adele and Taylor Swift as women who respected themselves, were devoted to their voices and who refused to conform to the standard expectations of women in the music industry. For a truly beautiful and sensual performance, give me Sade Adu, the British singer touring this country for the first time in 25 years in December. Here is a woman who understands you don't have to take your clothes off for a lads' mag to prove you are a real woman.
Churning out one manufactured fantasy after another, in which women are always presented as "up for it", doesn't constitute an expression of female independence or agency. The girls I spent time with saw it as co-operating in your own exploitation. "Miley exploits herself now," says one student, 13.
They wanted something more than a singing, dancing sexual puppet. Why can't the music industry give them that?
Melinda Tankard Reist


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Other than the win-loss record, the earliest barometer each fall about how well the Detroit Lions are playing is when the first questions start about the upcoming draft.
No matter what though, draft questions usually start at some point in October, six months before the three-day, made-for-prime-time NFL draft.
It's not just three days of 32 teams selecting for their future, it's a growth industry.
It's all amazing.
Here's something else. Mel Kiper, ESPN's draft analyst, said he saw it coming back when he was age 18. He jumped in and has not looked back.
"To see it the way it was when I started in 1978, the 1978 football season was my first year covering the draft, and to see it grow to this point, obviously I thought it could,'' KIper said in a recent conference call.
"I wouldn't have gotten into this business if I didn't think it had a chance to be successful and create this industry, as you said, which is huge. And think about what ESPN does with the draft and all the other entities that are covering this and the coverage on the internet and then the talk from August until April about the draft,'' he added.
We're less than three weeks away now from this year's version of the draft which starts the night of April 25 for the first round; April 26 for rounds two and three; and then April 27 wrapping it up with the final four rounds.
The Lions have eight picks -- one in each round with two in the seventh. Due to last season's 4-12 record, the Lions have the fifth overall pick. Last year in the first round (23rd overall) they selected Riley Reiff.
If a team doesn't draft well (Lions fans think Matt MIllen) they will not find success. It's that easy.
"The NFL has always been the king of all sports. The only way -- there was very few trades, free agency didn't exist. The only way your team changed its makeup from a year to a year and improved was the draft, and it was 17 rounds back in the day, then it was 12 rounds, then it became eight, then seven, and it's seven right now as we speak,'' Kiper said. "It's the only vehicle to improve your team, and people weren't able to see a lot of these players in the '70s and '80s. The only thing about that, you couldn't see players. Nobody watched players.''
Kiper did though. Back then he went to two games every Saturday and called schools to get film. He put in a big satellite dish so he could see as many games as possible.
Today statistics are readily available, you just have to know where to look. Back then the internet didn't exist.
"So you had to work hard; you had to do a lot of research to find out just tackles and sack numbers,'' Kiper said. "I had to call every school. The internet didn't exist. I had to call every school to get basic statistics on a player. You know how time consuming that was?''
He said he worked 20-hour days to get his annual draft book done which came out in early to mid-March.
"To see it grow to this point is tremendously satisfying for me because it's shown that back at age 18 I at least had the vision and the foresight to get into something that down the road became as huge as this is,'' said Kiper who predicts the Lions will draft cornerback Dee Milliner or defensive end Ziggy Ansah in the first round.
Last year the first round of the draft drew a combined 25.3 million viewers on ESPN and the NFL Network combined. It was an 18-percent increase over 2011.
The draft and the NFL Combine have made the NFL a year-round commodity even though the games last five months, including the playoffs.
Included in the process is the NFL Combine which has become so huge -- 7.25 million tuned into the NFL Network over four days in February. That was an 11-percent jump over 2012.
The Combine, the prelude to the draft, has become so popular that the NFL is considering selling seats at Lucas Oil Stadium in Indianapolis for it. And they will sell, even though it's just to watch hundreds of players run drills.
It's the NFL, that's all that matters.
(Follow @PaulaPasche on Twitter. Order her new book, "100 Things Lions Fans Should Know & Do Before They Die'' here. It's also available at bookstores.)


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Let It All Bleed Out
Man Behind Anti-Islam Film Gets Year In Prison
Mark Basseley Youssef also was ordered to serve four years of supervised release after his prison term. The sentencing by Judge Christina Snyder came in a Los Angeles federal court after a hearing Wednesday in which Youssef admitted using an alias, which prosecutors said violated his probation.
The amateur filmmaker from Cerritos, California, was identified in initial news accounts in September as Nakoula Basseley Nakoula, the name used in the bank fraud case. But the probation revocation case lists the defendant as Mark Basseley Youssef, which the filmmaker stated in court is his legal name.
In a plea deal, Youssef admitted to using a name other than his legal one; possessing a driver's license under the Nakoula name; possessing a fraudulent driver's license; and falsely telling his probation officer last month that he hadn't used the name of Sam Bacile, a name he allegedly used in making the controversial film.
While on probation, Youssef was prohibited from using any other name without consent of his probation officer.
Youssef's attorney, Steven Seiden, told reporters Wednesday that his client pleaded guilty in part because he wanted to save all parties the expense of going to trial. Prosecutors agreed to dismiss four other charges.
Youssef garnered international attention following protests against the "Innocence of Muslims" film throughout the Muslim world. The amateurish film portrays the Prophet Mohammed as a womanizer, buffoon, ruthless killer and child molester. Islam categorically forbids any depictions of Mohammed, and blasphemy is an incendiary taboo in the Muslim world.
The film was initially implicated in a violent demonstration in Libya that left the U.S. ambassador and three other Americans dead on September 11.
U.S. officials initially said the attack on the U.S. diplomatic compound in Benghazi and a nearby U.S. annex came as protesters outside the consulate rallied against the online video. But the Obama administration now says the incident was a terrorist attack, occurring 11 years to the day after the September 11, 2001, attacks on New York's World Trade Center and the Pentagon.
Still, the film, backed by hardcore anti-Islam groups in the United States, prompted protests in Egypt, Yemen, Tunisia, Morocco, Sudan, Iran, Iraq, Israel and the Palestinian territories when an Arabic translation of the film's trailer was released online a few weeks before the anniversary of September 11.
Youssef had been on probation since being released from federal prison in June 2011 after serving 21 months in the bank fraud case. Assistant U.S. Attorney Robert Dugdale said in court Wednesday that the new sentence was appropriate, asserting Youssef's use of aliases was part of "a long-running pattern of deception," and that the film's actors and actresses "had no idea he was a recently released felon."
Cast and crew members have said they didn't know that they were shooting a film having anything to do with Islam or the Prophet Mohammed. The prophet's name was dubbed in after the film was shot, some of them have said.
Seiden said Wednesday that Youssef admits to being the film's writer, and that he might also have been a "cultural consultant" on the film.
Source -


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Make the honor roll, go for the promotion, or try the tastiest entrée on the menu. In almost every facet of our culture, we are told to "go for the gold." So, why settle for "good enough" when "something better" is within reach? According to a new study in the Journal of Consumer Research, constantly striving for the best may be magnifying negative feelings like regret and dissatisfaction in other parts of our daily lives.
"We found that individuals who have a 'must have the best' mindset experience more regret and are less satisfied with the products they purchase or consume. They are also more likely to return the items or switch brands entirely," write authors Jingjing Ma and Neal J. Roese (both Kellogg School of Management, Northwestern University).
Across seven experiments, the authors examined the impact of what they term the "maximizing mindset" on participants' ability to make decisions when they are feeling or behaving in a certain way. Consumers with a maximizing mindset typically have a tendency to compare and adopt a goal of getting the best, even if it requires them to work harder, search more deeply, and ultimately perform better than their peers.
In one study, participants played a computer game that measured typing speed and were told the response times were a measure of their intelligence levels. Next, participants were asked to select a brand of backpack from a list of five choices and describe the features of their current backpack. The test takers were then given false computer game results that ranked them as either in the top 10% of intelligence level or below average. The researchers found that the participants who received poor test results expressed more regret about their backpack choice than those who fell in the top 10%.
"Our research shows the potential impact of the maximizing mindset on post-purchase regret, customer satisfaction, and brand loyalty, particularly for companies claiming to offer the best available product on the market. We also offer an insight on the impact the maximizing mindset has on our daily lives. Constantly comparing and focusing on getting the best can have a negative effect on our psychological well-being, particularly when we do not get the best," the authors conclude.
Jingjing Ma and Neal J. Roese. "The Maximizing Mind-Set." Journal of Consumer Research: June 2014. For more information, contact Jingjing Ma (email@example.com) or visit http://ejcr.


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February 10, 2012
Information and Communication Technologies for Development
This paper provides a snapshot of agriculture solutions that are emerging through information and communication technologies. It describes how these solutions are beginning to be...More
March 1, 2010
The Use of GIS in Crop Disease Management
This document summarizes the contributions and use of geographic mapping tools (GIS/GPS) in a disease management project. It discusses challenges that the project encountered. It...More
March 1, 2010
Final Report on the Great Lakes Cassava Initiative
Cassava roots account for more than one third of all kilocalories consumed in many parts of the Great Lakes Region of sub-Saharan Africa. Cassava Mosaic Disease and Cassava Brown...More
April 20, 2015
Delivering Health Microinsurance through Savings and Internal Lending Communities
Catholic Relief Services and partners piloted a health microinsurance product and delivered it through savings groups in Benin. We introduced a digital solution to improve...More
October 4, 2011
Tools for Field Staff›Guidelines
Institutional Strengthening
Institutional Strengthening is a reference for organizations that wish to develop or improve existing institutional strengthening systems and processes. It presents principles,...More
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Mapping mHealth Success
This report provides an overview of CRS' Reducing Maternal and Newborn Deaths (ReMiND) project developed a mobile application for Accredited Social Health Activists (ASHAs) and...More
January 20, 2017
Midterm Evaluation Summary
This report summarizes the midterm evaluation of the Reducing Maternal and Newborn Deaths Project (ReMiND) conducted by CRS in 2014. The evaluation included a qualitative study...More
January 20, 2017
Six steps to mHealth success
The Reducing Maternal and Newborn Deaths (ReMiND) project offers solutions to community-level health systems bottlenecks in India and globally. The six key steps in ReMiND's...More
January 20, 2017
Tools for Field Staff›Learning Briefs
Strengthening Community Health Systems through mHealth
This learning brief outlines the impacts of a mobile application for Accredited Social Health Activists (ASHAs) that was developed by CRS' Reducing Maternal and Newborn Deaths (...More
February 9, 2017
Research›Case Studies
Implementing the Principles for Digital Development
This case study illustrates how CRS and its partners have been implementing the Principles for Digital Development since 2011 in The ReMiND Project in the Kaushambi district of...More


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Last night I was reunited with the gf.
She had dinner with a classmate, so when I got back to Yotsuya I decided to make some curry risotto rice with vegetables and pork.
By the time I was almost done she came through the door and still had room for some of my dinner.
Today we slummed it, resting most of the day.
When we finally left the house we made our way to the Yotsuya library so I brought back those CDs I last had. In its place I borrowed Best of T-Rex and Nirvana, Nikka Costa (feat. Lenny Kravitz), and a Rolling Stone magazine.
We went into Shinjuku after that. There are a lot of clothing sales at the moment. The gf was looking for a new dress for a wedding she'll be going to in two weeks. I patiently tagged along.
On our way home we had sushi together for the first time.
Maybe it's strange after almost seven months in Japan for me to not have done it sooner. While none of the fish tasted bad, I still prefer to eat sushi in small doses. I'm just not used to eating fish raw.
This is some funny english from the menu.
"We recommend this tasty tuna with BIG CONFIDENT!" and "semi fatty tuna", "mostly fatty tuna". I didn't think fish had fat. Yes, it was tasty.
Sunday, 6 January 2008
Raw Like Sushi
Last night I was reunited with the gf.


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If you have any questions regarding the 13th Annual AMCSI Conference, please don't hesitate to contact AMCSI at firstname.lastname@example.com.
With a condition so rare that only one in 3000 babies born have this neuromuscular disorder it's easy to comprehend how alienated anyone with arthrogryposis multiplex congenita (AMC) must feel. Through the hard work of one mother's vision and an army of members, the AMC support group has helped bridge the gap with the power of the internet. It is not only the group's mission to provide and encourage a greater understanding and awareness of this condition, but also to provide a support system. To help those that have felt all their lives an outcast or alone, meet others who have lived that same life, to meet other families who have the same concerns and to provide a resource of information.
But meeting online is not enough. It's hard to explain to a mom exactly how another mom has taught her child to sit up without the use of his arms, or how one child learned to stand. What so many people take for granted: the ease of walking, typing, eating and breathing those with AMC have had to struggle to adapt to this world. Our conferences solidify that bridge and strengthen the bond of our AMC family. Once a year we come together, bring professionals, doctors, physical therapists, occupational therapists, provide workshops and invite people throughout the world to learn, share, laugh, cry and grow.
Interested in advertising at the conference? Click here.
If you have any questions regarding the 13th Annual AMCSI Conference, please don't hesitate to contact AMCSI at firstname.lastname@example.com.