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Cubs manager Dale Sveum and team president Theo Epstein believe the Cubs will take a big step forward this season, and I'm thinking, I guess losing only 90 games would be a big step.
Another 100 losses, however, is easily attainable, don't kid yourself. The execrable Astros have left the NL Central. Heck, they've left the National League. That's fewer chances to beat a patsy, and that's why the Cubs ought to remember Matt Damon's opening line from the seminal poker classic "Rounders:''
"Look, here's the thing: If you can't spot the sucker in the first half-hour at the table, then you ARE the sucker.''
Who plays the sucker better than a franchise that comfortably wears any and every century mark of futility?
The Cubs appear to be marginally better this season. They still have a toxic waste dump at third base, perhaps offset by a full season of Anthony Rizzo. Who knows what they have at catcher, and who knows what he'll be catching from that staff. There's no reason to think the Cubs will run the bases any smarter, but perhaps they'll work more pitches at the plate.
Maybe the so-called big step is a better brand of losses.
More importantly, we need to see a better brand of trades by Epstein and General Manager Jed Hoyer. By the way, they're already trailing in that category. So Cub.
The Cubs signed Scott Baker after arm surgery, and Baker got hurt immediately. Epstein and Hoyer could draft for the Bears.
So, the Cubs open the season with Baker and Matt Garza on the Too Disabled To Trade List. Say this for the new TheoThink: The Cubs can be screwed as easily by someone else's bad trade as by their own dumb signings.
Baker was supposed to be the new Paul Maholm. One of them, anyway. How's that for setting the bar high? But the point was, the Cubs hoped to get lucky with an arm surgery patient and turn their $5.5 million investment into young talent.
Garza, meanwhile, was supposed to be Garza, a No. 1 pitcher, at least on this team. Garza isn't an ace on a good team, but the idea was that a contender team would pay a big price. Short of a "Matt Garza MRI'' giveaway day at Wrigley, I don't know what the Cubs will get out of this guy.
In my world, Epstein and Hoyer blew it last year, waiting on trading Garza and then messing up the Ryan Dempster episodes twice.
They thought they traded Dempster, except they didn't get an official OK from Dempster, who had no-trade rights. Word of the leaked out of the building at Clark and Addison. Apparently some of the stupid gas that used to leak out of that building during Tribune Co.'s legendary ownership was still pumping.
Dempster said no to the Braves. He wanted the Dodgers. Epstein and Hoyer didn't have a deal with the Dodgers. Oops. Dempster refused to say yes to the Braves, and Epstein and Hoyer got pantsed.
But wait. There was more. It leaked out again that they let Dempster listen to phone conversations with the Dodgers. The Dodgers didn't know Dempster was listening as they were explaining why they didn't want him. Oops, part deux.
Have Epstein and Hoyer ever done this trade thing before? We've seen the Cubs audition for amateur hour many times, but this was one of the dumbest episodes by supposedly smart guys.
And they never dealt Garza. Still haven't. They waited and waited, and Garza got hurt last year. He came back this year and called shotgun on the disabled list for most of spring training and right into the regular season.
Epstein and Hoyer eventually traded Maholm to the Braves for less attractive prospects than they believed they were getting in the Dempster deal. That was supposed to be Baker this season, but he'll be out until June. Maybe Scott Feldman and Edwin Jackson will have two good months and get some interest from prospective trade partners. Maybe Epstein and Hoyer will make quicker moves when their inventory of the most injured position in the game is actually healthy.
One other question: Why is Carlos Marmol still here?
I know the lip service Epstein and the Cubs have given to each season, but it's a lot of hooey for this franchise this year, same as last year. Epstein had better change his mantra. The only thing sacred about this season is a chance to draft well and dump every older and marginal player with a blip of trade value:
Garza, Baker, Feldman, Jackson, Marmol, David DeJesus, Nate Shierholtz, maybe Welington Castillo, certainly David DeJesus, maybe Darwin Barney, certainly Alfonso Soriano, maybe even Jeff Samardzija, but certainly the rest of the bullpen except for Ryuji Fujikawa.
That's your Cubs season right there. Those are the wins and losses that matter. It's not what the players can do on the field, it's what Epstein and Hoyer can get for them. That's the real meaning of "Go Cubs, Go.''
Epstein and Hoyer aren't as inspiring as they seemed a year ago. They looked sloppy at times. It's worth reminding that Epstein has never turned this kind of rebuilding into a World Series champion. He certainly hasn't done it without a 'roided-up middle of the order.
Epstein's Boston era, however, drafted and developed terrific players who contributed to and in some cases led those championship teams. Some of those drafting loopholes have closed. That places more importance on finding and executing deals without someone listening in.
If you're keeping score at home, much of the Cubs' success depends on Epstein and Hoyer making trades better than Tom Ricketts makes stadium deals.


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During the past few years, much as been written (some of it by me) about the advantages of alternative investments in client portfolios. Apparently, advisors and the public have been listening. According to Morningstar, in 2007 alternative mutual funds brought in only $2.8 billion; by 2010, inflows had grown six-fold to $18.8 billion.
The reasons behind this meteoric success aren't hard to figure: during the decade ending March 31, 2010, the S&P 500 Index (total return) was down 6.36%, or 0.66% per year, while hedge funds (as measured by the HFRI Fund Weighted Composite Index) were up 77%, or 5.9% a year, and managed futures mutual funds (as measured by the Altegris 40 Index) were up 115%, or 8.0% annually.
What's more, non-correlated alternative funds are well suited to allocated portfolios: From January 1997 to Jan 2012, Managed futures had a -0.15 negative correlation to the S&P. During this same period, the S&P had an annualized standard deviation of 16.5% vs. 10.5% for managed futures and 6.1% for Global Macro funds, all of which can reduce portfolio risk dramatically.
Another reason for alternative funds' recent success is that in recent years, hedge fund managers have warmed to the mutual fund format. "Many hedge fund managers who wouldn't have considered this before, are doing it today," said Jon Sundt (left), president and CEO of Altegris Advisors, which manages some $3.4 billion in alternative funds. "Some hedge funds showed massive redemptions. And there's been fee compression; Hedge fund managers who used to get 1% plus 20% of their gains, are now willing to work for a flat fee. Also, after the credit crisis, long/short managers are using lower leverage: less than two to one, which is required by mutual funds."
Unfortunately, while the mutual fund structure is easier for advisors to manage in client portfolios, many advisors are not aware that there are critical differences between funds that use alternative strategies and funds holding more traditional asset classes.
To help advisors better understand these differences, Altegris recently launched the Altegris Academy, an advisor-only website which offers detailed information on alternatives including the fundamentals and more sophisticated 'How To' solutions. The site contains articles, white papers, videos and analytical tools to better incorporate alternatives into client portfolios.
According to Sundt, advisors' failure to understand the differences of alternative funds can lead them to make any combination of four major mistakes:
- Advisors often choose the wrong managers.
"There is a lot of junk out there," said Sundt, including "long/short and macro funds with underlying managers with questionable track records, and without a deep infrastructure to support them. With a large cap value fund, for instance, when the index goes up, every large cap manager goes up. If you get the asset class right, you've won."
But in the alternative world, he points out, there's not as much correlation between managers: one fund can be long, while another fund is short. "That creates a huge disparity between similar funds," Sundt says. ". One long/short fund might be up 40% while another is down 40%. It's really important to focus on talent."
Sometimes firms will have a sound track record, but for too short a period. Sundt recommends that each of a fund's sub managers have a 10-year track record. For managers with a shorter history, Altegris analytics enables advisors to simulate their performance over a longer period.
- Some strategies aren't viable for '40 Act mutual funds.
Usually the issue here is one of liquidity. Distressed debt, event anticipation, and private equity are investment strategies that typically don't work well in a mutual fund structure.
Strategies that do work well include Managed futures, global currencies, global macro, long/short equity, emerging markets, and small cap and micro cap, provided stocks held have sufficient liquidity.
- Most hedge fund managers don't want to replicate their hedge fund in a mutual fund.
"They'd lose their high-paying hedge fund customers," says Sundt. "Top managers want access to top money that mutual funds can bring in, but they don't want to jeopardize their franchise and disclose all their holdings." To get around this problem, Altegris and other mutual fund sponsors combine multiple hedge fund managers into each mutual fund. That way, when fund holdings are disclosed, it's not clear who holds what. And investors who want a portfolio managed by one specific manager still will be drawn to his hedge fund.
- Fees can be higher.
"If you find a good manager, they are going to want bigger money," says Sundt. "They can't get their usual 1 and 20 in a mutual fund, but we can pay them up to 2%."
Yes, that's more than your typical mutual fund. But for managers who have a record of beating the market with lower risk, and low correlation, it maybe one of the best investments that advisors—and their clients—make in the coming years.

subset: commoncrawl


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Crowdsourcing gains traction as a resource in legal practice
For inexperienced lawyers, the amount of research and case law that must be studied can prove overwhelming, especially in areas of the law that are newer or uncharted. Even for attorneys who have years of experience, using online research services can be extremely costly, not to mention time-consuming.
So why not turn to the crowd?
Crowdsourcing, a concept that fuels many social networks, is starting to gain traction as a viable option in the legal industry. In its simplest form, crowdsourcing involves seeking input or advice from a large group, usually online. Social media networks like Twitter have helped to facilitate crowdsourcing, allowing information to be shared and spread quickly.
It was the concept of seeking advice from peers that motivated Adam Ziegler, a former litigator in Boston, to start Mootus, an online platform for legal argument and insight.
"I thought there should be a way - given that the law is public - that legal proceedings should be some way to tap into that, for lawyers to discuss, argue and explore legal issues on the Web," Ziegler said.
The more he learned about crowdsourcing, the more it made sense as a potential tool for lawyers. Decisions in the American legal system emerge as a series of decisions over time, he pointed out, "not so much with one court dictating, but a bunch of different sources, usually in uncoordinated activity.
"That, to me, is a form of crowdsourcing, just a lot slower and more inefficient."
On Mootus, users can propose an issue for argument. For instance, "Is a Facebook 'like' considered free speech protected by the First Amendment?" and other users can weigh in, citing case law or other opinions. Users then vote on whether citations are "on point" or "off base," which helps earn status that gives their input more weight.
Mootus isn't just a popularity contest, though, Ziegler said, but a way for lawyers to practice the much-needed skill of effective argument. "Junior lawyers don't do enough citation of primary law before they enter practice," he said.
For Jake Heller, a former litigator with Boston law firm Ropes & Gray, the idea of using already-existing sources of legal expertise was something he had considered since graduating from Stanford Law School.
"I saw how every other field of information had been revolutionized by crowdsourcing," Heller said, offering examples such as restaurant review site Yelp, online encyclopedia Wikipedia, and GitHub, whose online repositories allow collaboration on software development projects. "I kept thinking, 'When will law catch up?' "
He quit his law firm job to start Casetext, which launched last summer. In addition to contributors, the site aggregates free, publicly available content from such sources as law firms' websites and law professors' personal blogs, and presents it alongside legal documents as annotation.
"Lawyers are already producing a lot of information for free - literally thousands of summary analyses," Heller said. "What (motivates) them to write for free, under certain circumstances, is that it helps them build their brand and establish expertise."
The idea of crowdsourcing and collaboration already is prevalent in the legal field, Ziegler notes, in the form of the amicus curiae brief, which allows a third party to offer information or opinion on a case in which it is not directly involved, but may have an interest.
And, he noted, it's important not to confuse crowdsourcing - which is seeking input and opinions from many people - with crowdfunding, which involves seeking monetary contributions. Ziegler said Mootus is not a crowdfunding site, nor are there plans to make it one.
Heller said he thinks that, while sites like Casetext and Mootus provide a valuable service, there will always be a place for the more traditional forms of legal research.
"But I think these major large services have to grapple with how sustainable their prices are," he said. "As law firms are having a harder time financially, they may start to ask themselves how they can afford to pay for an expensive site when there is content being produced for free."
Explore further
©2014 Pittsburgh Post-Gazette
Distributed by MCT Information Services


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Prince Harry has seen and done a lot in his 32 years.
In a candid conversation with Newsweek's Angela Levin, Harry looks back on the death of his mother, Princess Diana, who was killed in a car crash in 1997. "She had the most wonderful sense of humor and always wanted to make things fun for us," he says, "as well as protect us."
Sharing fond memories his mother—and carrying on her charitable legacy—comes easily. But talking about Diana's funeral is much more difficult for Harry, who was 12 at the time. "My mother had just died, and I had to walk a long way behind her coffin, surrounded by thousands of people watching me while millions more did on television. I don't think any child should be asked to do that, under any circumstances," Harry recalls. "I don't think it would happen today."
Harry "shut down" his emotions for nearly two decades, until his older brother Prince William encouraged him to seek professional help at age 28. "My search began when I was in my mid-20s," says Harry, who admits he partied too hard. "I needed to fix the mistakes I was making."
The prince now wants to be seen as a passionate, emotional person. "Sometimes, I can have too much passion," he tells Newsweek. "It has got me into trouble in the past, partly because I cannot stand the idea of people mincing around the subject rather than just getting on with it."
Now that he's older, Harry can better appreciate his role in the royal family.
"My mother died when I was very young. I didn't want to be in the position I was in, but I eventually pulled my head out of the sand, started listening to people and decided to use my role for good. I am now fired up and energized and love charity stuff, meeting people and making them laugh," says Harry, who retired from the army two years ago. "I sometimes still feel I am living in a goldfish bowl, but I now manage it better. I still have a naughty streak too, which I enjoy and is how I relate to those individuals who have got themselves into trouble."
Maintaining an "ordinary life" is a top priority. "My mother took a huge part in showing me an ordinary life, including taking me and my brother to see homeless people. Thank goodness I'm not completely cut off from reality. People would be amazed by the ordinary life William and I live. I do my own shopping. Sometimes, when I come away from the meat counter in my local supermarket, I worry someone will snap me with their phone. But I am determined to have a relatively normal life, and if I am lucky enough to have children, they can have one too," says Harry, who is now fifth in line to the throne. "Even if I was king, I would do my own shopping."
In a time when stars are "Just Like Us," he hopes there's still an air of mystery about the royal family. "It's a tricky balancing act," says Harry, who declines to discuss his personal life. "We don't want to dilute the magic…The British public and the whole world need institutions like it."
"The monarchy is a force for good, and we want to carry on the positive atmosphere that the Queen has achieved for over 60 years," he continues, "but we won't be trying to fill her boots."
Along with his brother and sister-in-law, Kate Middleton, Harry has been shaking things up a bit. "We are involved in modernizing the British monarchy. We are not doing this for ourselves but for the greater good of the people. Is there any one of the royal family who wants to be king or queen?" Harry asks. "I don't think so, but we will carry out our duties at the right time."
With so much attention on Prince George and Princess Charlotte, now is the time for Harry to "make something of my life," he tells Newsweek. "I feel there is just a smallish window when people are interested in me before [the siblings] take over, and I've got to make the most of it."


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ILCC?Softball Clinics April 20-21
Iowa Lakes Community College softball program will hold Softball Clinics on Saturday, April 20, and Sunday, April 21, in Estherville.
The clinic will be divided into three units. The first will be a Youth Clinic serving those ages 5-12 where participants will go over the 'mechanics' of throwing & catching, fielding, base running and hitting. That session will be held from 10 a.m. to noon on April 20.
The Sunday, April 21, clinics will focus on Advanced Hitting and Pitching and are open to all ages. The Hitting clinic runs from 10 a.m. to 11 a.m. Topics covered will include hitting mechanics, drills and mental training.
The Lakers Softball team has another double-header following the hitting clinic, which starts at 12 p.m.
After the games are finished, the last clinic will begin. It's an Advanced Pitching Clinic, which will be held from 4 p.m. to 5 p.m. It will cover pitching mechanics, including the drop/change/rise/curve pitches as well as mental training for a winning attitude. This is also open to all ages; however, each pitcher is required to bring a catcher and organizers would prefer it is a parent or coach.
Participants may select one or all three of the clinics. All sessions will be held at the Softball Field or Christensen Building on the Estherville campus of Iowa Lakes.
To register, contact Coach Jessica Van Loy at 712-362-7928 or mailto


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loadVbCss(yuipath + '/treeview/assets/skins/sam/treeview.css');
Become A Better FishermanbyPublished on 17-09-2015 03:43 AM
The following information is provided courtesy of ALVEY REELS
The sole purpose of this information is to help you become a better angler - to give you good basic information that will make your fishing trips in Australia more enjoyable and let you fully enjoy this relaxing, fulfilling sport.
Alvey Reels Australia, Snyder Glas Rods and Platypus Lines are all privately owned Australian companies that manufacture in Australia. The following information draws from the 200 years of combined knowledge gained from manufacturing a wide range of quality products to suit Australian fishing conditions and from top competitive anglers.
Many books have been written giving instructions to the novice or beginner in the art of angling. Most have defeated their purpose by showing every conceivable knot, serving only to confuse and discourage the reader.
This information shows comparatively simple methods which have been developed and accepted by top competitive fisherman to give the maximum efficiency. Having been proved conclusively in keen competition, these methods can be recommended with confidence as being worthy of a try by all fishermen.
Important Environmental Notice
Remember for fishing to improve we all have to be responsible ... don't litter empty bait bags, beer ring packs ... discarded fishing line should never be thrown in the water ... always return undersized fish, never take more fish than you need.
Fishing Styles
Fishing VarietiesbyPublished on 17-09-2015 03:49 AM
BEACH FISHINGAustralia is fortunate in possessing some of the finest beaches in the world, and with them, excellent fishing. The ever changing formation of our beaches due to natural forces provides both shelter and food for a variety of fish. By learning to "read a beach, you can locate all the popular angling species such as Tailor, Salmon, Flathead, Mulloway, Trevally, Dart, Bream and Whiting.
THE GEAR SUCCESSFUL SURF FISHERMAN USES: ...byPublished on 17-09-2015 03:52 AM
ROCK FISHINGRock fishing can produce some excellent sport for those who are proficient at it. It must be stressed that this is not for the rank amateur. Of all the types of fishing styles, it is the most dangerous. There is some hard and fast rules ...byPublished on 17-09-2015 03:53 AM
The large number of rivers, estuaries and lakes along the Australian coastline and the variety of fish species that frequent them, offer the main source of recreational fishing for the angling public. As with all types of fishing the choice ...byPublished on 17-09-2015 03:56 AM
The upsurge in trailer boat popularity along with the ever improving boat and motor design has seen the offshore reefs come well within range of boat fishermen. Electronic navigation aids such as GPS and LCD fish finders have opened up a new world for the reef fisherman. The safety aspect has been improved by the formation ...byPublished on 17-09-2015 03:58 AM
Freshwater angling over the last few years has experienced a meteoric rise in popularity, due in the main to the stocking with native fish of impoundment's and rivers. Most of our apparently barren ...


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Effects of Resveratrol Supplements on Vascular Health in Postmenopausal Women
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT01564381
Recruitment Status : Completed
First Posted : March 27, 2012
Last Update Posted : July 14, 2017
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
|Condition or disease
|Cardiovascular Disease
|Dietary Supplement: ResA Dietary Supplement: Resveratrol Dietary Supplement: Placebo
|Phase 1 Phase 2
Cardiovascular disease is the leading cause of morbidity and mortality in the United States. To reduce the risk of cardiovascular disease (CVD) and its associated health care costs, nutrition and health recommendations strongly advocate the consumption of a diet rich in fruits and vegetables. In addition to essential vitamins and minerals, fruits and vegetables contain a number of bioactive compounds that may be involved in vascular function.
The "French Paradox" refers to diet patterns that, despite being high in saturated fat, are associated with a relatively low cardiovascular risk. An important aspect of many of the diets that were identified in the French Paradox studies is a significant intake of wine, particularly red wine, which can contain an array of phytochemicals that have been postulated to improve cardiovascular health. A polyphenolic that has received particular attention is this regard is resveratrol.
The stilbene resveratrol is found predominately in red grapes, red wine, peanuts and some berries, and it has been touted in the popular press for its potential health-promoting benefits. Emerging evidence suggests a role for resveratrol in the protection against numerous degenerative health problems including CVD and certain cancers, diabetes and some forms of neurodegeneration.
The amount of resveratrol in most foods is very low; thus obtaining the amounts of this compound that have been associated with improved health in animal models is difficult for humans. ResA is a product produced using patented technology that physically binds resveratrol to arginine, creating a novel conjugate. In the preliminary studies the ResA conjugate produced higher peak plasma levels, as well as total plasma levels that persist for a longer period of time when fed to rats. Whether similar results would occur in humans, and the extent to which increasing blood resveratrol concentration can be associated with positive cardiovascular effects in an at-risk population is the subject of this project.
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|64 participants
|Intervention Model:
|Crossover Assignment
|Double (Participant, Investigator)
|Primary Purpose:
|Official Title:
|Effects of Resveratrol Supplements on Vascular Health in Postmenopausal Women
|Study Start Date :
|March 2012
|Actual Primary Completion Date :
|March 2015
|Actual Study Completion Date :
|March 2015
Experimental: Resveratrol
The capsules will contain 90mg of resveratrol.
Dietary Supplement: Resveratrol
90mg of resveratrol.
Experimental: ResA
ResA is a product produced by using patented technology that physically binds resveratrol to arginine, creating a novel conjugate. The capsules will contain 90mg of resveratrol.
Dietary Supplement: ResA
90mg of resveratrol conjugated with arginine.
Placebo Comparator: Placebo
The placebo will be cellulose.
Dietary Supplement: Placebo
Made up of cellulose.
- Bioavailability of a novel formulation of resveratrol (ResA) compared to a standard resveratrol supplement [ Time Frame: up to 2 hour after consumption ]We will assess metabolites concentrations of resveratrol and ResA in plasma via HPLC method.
- Change in vascular function in response to ResA compared to native resveratrol [ Time Frame: up to 2 hours after consumption ]We will assess changes in vascular function measured by peripheral arterial tonometry.
- Change in platelet reactivity in response to ResA intake [ Time Frame: 1 hour after consumption ]We will assess platelet function in response to ADP, collagen and arachidonic acid as measured by platelet aggregometer.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|50 Years to 70 Years (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- 50 to 70 years of age
- Lack of menses in the last year and FSH 23-116.3 mlU/mL
- Subject is willing and able to comply with the study protocols.
- Subject is willing to consume resveratrol supplements/placebo capsules on three separate occasions.
- BMI 18.5-34.9 kg/m2
- Weight ≥ 110 pounds
- LDL-C ≥ 130 mg/dL
Exclusion Criteria:
- BMI ≥ 35 kg/m2
- Self reported use of anticoagulation agents including NSAIDs
- Self reported use of oral cortisone or other immunosuppressive agents,
- Self reported underlying neoplasia or immunological disease
- Food faddists or those taking a non-traditional diet
- Self reported physical activity restricted or reduced due to chronic health conditions
- Self reported diabetes
- Blood pressure ≥ 140/90 mm Hg
- PFA-100 readings 10 % outside of normal reference range (normal reference range for ADP-Collagen: 71-118 sec; Epinephrine-Collagen: 94-193 sec).
- Self reported renal or liver disease
- Self reported heart disease, which includes cardiovascular events and stroke
- Self reported Cushing's syndrome
- Self reported chronic/routine high intensity exercise
- Inability to properly place or wear the PAT probes or abnormal measurements on pre-screening PAT
- Abnormal Liver, CBC or Chemistry panels (laboratory values outside the reference range) if determined to be clinically significant.
- Self reported cancer within past 5 years
- Self reported history of psychiatric disorders i.e. schizophrenia or bi-polar or depression treated with antidepressants within the last 1 year.
- Self reported use of MAOI inhibitor within the last 1 year (e.g. phenelzine (Nardil), tranylcypromine (Parnate), etc)
- Self reported malabsorption (e.g. difficulty digesting or absorbing nutrients from food,
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01564381
|United States, California
|University of California, Davis - Ragle Human Nutrition Research Center
|Davis, California, United States, 95616
|Principal Investigator:
|Robert M Hackman, PhD
|University of California, Davis
|Responsible Party:
|University of California, Davis
|ClinicalTrials.gov Identifier:
|Other Study ID Numbers:
|First Posted:
|March 27, 2012 Key Record Dates
|Last Update Posted:
|July 14, 2017
|Last Verified:
|July 2017
Cardiovascular disease
Cardiovascular Diseases
Anti-Inflammatory Agents, Non-Steroidal
Analgesics, Non-Narcotic
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Anti-Inflammatory Agents
Antirheumatic Agents
Antineoplastic Agents, Phytogenic
Antineoplastic Agents
Molecular Mechanisms of Pharmacological Action
Protective Agents
Enzyme Inhibitors
Platelet Aggregation Inhibitors
Antimutagenic Agents
Anticarcinogenic Agents


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|Indemnitor Obligations
By cosigning a bail bond one inherits a certain responsibility for the accused person they are cosigning for. In most cases the cosigner of a bail bond is our first point of contact if we need to get in touch with a defendant for instance if they miss court or their phone number is no longer valid.
Indemnitor (co-signer) Must:


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Advanced Search
July continued the trend of increasing contract awards that Washington Technology has covered since the beginning of the year. Who stole the show this month?
SAIC has won a $17 million contract with the Indian Health Service to replace its dental records system.
SAIC has won a $7 million Navy contract to provide the U.S. Fleet Forces Command with integrated training and support and execution. The contract was awarded without competition.
SAIC has won a $38 million task order under DISA's ENCORE II contract to provide command and control systems and technical services support to U.S. combatant commands.
SAIC has won a contract with the Army Medical Research and Materiel Command to support clinical research work with project management services.
Greece is being ordered by an international arbitrator to pay SAIC $52 million related to a breach of contract over a command and control system that the company delivered for the 2004 Summer Olympics.
SAIC has won an option with the Navy to support the Military Sealift Command's IT ashore operations.
Thirteen companies have won a contract with the Navy to provide integrated cyber operations services in support of C4ISR systems. They'll now compete for task orders for a variety of services. Who captured this plum prize?
ITT Exelis has won a subcontract with SAIC to provide engineering services toward DARPA's Adaptive Radar Countermeasures program.
SAIC has agreed to pay a sum of money to settle allegations that it violated the False Claims Act through a contract that GSA awarded the company back in 2006.
June brought another increase in the number of contract awards that we've covered during the month, marking the continuation of a trend we've followed since January. So who are June's big winners?
Four companies have won a contract with the Navy to support the Office of the Secretary of Defense's Defense Readiness Support System.


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You might have noticed that the Twitter Mailbag was on hiatus this past week as I was off learning how to change an infant's diaper.
Now that issue is sorted out – mostly – the TMB is back to answer your questions on everything from Quinton "Rampage" Jackson's complicated legacy to Ronda Rousey's practice of using YouTube as a source for hard-hitting news.
If you've got a question of your own, you can find me on Twitter at @BenFowlkesMMA. Please try not to tweet at me in all caps, however. The baby is sleeping, and I have no idea what to do if she wakes up.
* * * *
@benfowlkesmma Sadly Rampage's PRIDE days + UFC title run seem long forgotten, Will we remember him as a LHW great or an aging whiner? #TMB
— Alex Larsen (@LAR13) January 23, 2013
Can't we remember him as a little of both? Throughout his career, when "Rampage" Jackson was interested and motivated and fully present, he was an excellent fighter capable of knocking your head off your shoulders. He was also a bit of a mental case, prone to paranoia and in possession of an endless supply of excuses when he came up short. To ignore any of those aspects of Jackson's career is to tell ourselves a lie about who he is/was.
Jackson displayed flashes of greatness as well as lethargic indifference. He was a charismatic champion who gave himself the benefit of every possible doubt, while also accusing virtually everyone else he came in contact with of being out to get him. He was responsible for some of PRIDE's most memorable moments (on both the winning and the losing end), and he remains the only UFC fighter to ever lead police on a car chase while driving a monster truck with his picture on the side. All of that – the not-fully realized potential, the moments of brilliance, the paranoid conspiracy theories about people poisoning his food and spying on his training camps – is part of the "Rampage" story. It's a package deal, like it or not.
@benfowlkesmma Whats your thoughts on GSP saying Hendricks didnt deserve a title shot cause GSP thought he lost to Koscheck, even though….
— Travis Wansitler (@tdub_72) January 23, 2013
@benfowlkesmma He is now fighting a guy who just lost to Carlos Condit.So do you think this is a double standard to make more $?
— Travis Wansitler (@tdub_72) January 23, 2013
My thoughts are that I'm sick of people arguing in favor of one contender or against another based on their opinion of who should have won a decision. That's not how this works, people. Judging in MMA is an imperfect system, and sometimes even a downright baffling one, but that doesn't excuse us from making up our own results.
Nick Diaz lost via decision in his fight with Carlos Condit. Johny Hendricks won via decision in his fight with Josh Koscheck. Those are facts. You don't have to agree with the judges, but you also don't get to rewrite MMA history by pretending that the winner was the loser. We can't start basing future matchmaking decisions based on how one guy who was not responsible for determining the outcome saw it. That's ridiculous, and Georges St-Pierre does not strike me as a ridiculous person. Seems to me that GSP came up with his own idea of who he wanted to fight first and then came up with the reasoning to justify it second.
@benfowlkesmmaif we suspected Belfort of TRT use in his fight with Jon Jones, should we still be giving him credit for his win vs Bisping
— Christopher Cheung (@christopher_kit) January 21, 2013
This is the sort of question I think we're going to keep coming back to with the issue of testosterone-replacement therapy, much the same way Major League Baseball is revisiting a similar question regarding its own "steroid era." If we know or even just strongly suspect that an athlete had help from a performance-enhancing substance, what does that do to how we view the things they may have accomplished under the influence of it?
It's not just Vitor Belfort, who will neither confirm nor deny that he's ever sought a therapeutic-use exemption for testosterone. What are we supposed to do about the ageless wonder Dan Henderson, who's been on TRT for years now? What about Chael Sonnen and Forrest Griffin? If you win a fight while on TRT, is it like hitting a home run on steroids? How about if you win a UFC title?
Right now I think our sport is still struggling to come up with the answer. But, like baseball, once we do, our history might not be so kind to the current crop of TRT users.
@benfowlkesmma #TMB Is Rashad Evans the biggest threat and most exciting matchup against A.Silva at 185? There is noone else.
— andemz (@andemz) January 22, 2013
Really? There's no one else at 185 pounds except for a guy who is not, as of yet, actually at 185 pounds? I don't buy it. There's Chris Weidman, for one. I know Anderson Silva and his camp claim he hasn't done enough to earn a shot, but something tells me that if they really thought he was so woefully overmatched and out of place against the champ, they'd welcome that fight like it was a rematch with James Irvin. There's also Luke Rockhold, the last Strikeforce middleweight champ, who has arguably as much claim to an immediate UFC title shot as Gilbert Melendez does. Then there's Ronaldo "Jacare" Souza, who's recently added some striking skills to his already formidable ground game. And, if Hector Lombard can avoid getting Okami'd in March, I don't see how he's not in the contender conversation at middleweight.
@benfowlkesmma #TMB what happens to Sonnen if you loses to Jones? Does he move back down to MW where he's lost twice to AS or stay at HW?
— Joshua Arambula (@mataleonmma) January 23, 2013
I assume you mean "stay at light heavyweight" since he has yet to fight as a heavyweight. Of course, that doesn't mean he won't. The way Chael Sonnen's going, a loss to Jon Jones might only encourage him to move up another weight class and immediately challenge Cain Velasquez. And, the way things in the UFC are going, he'd probably get that fight, too. If he lost that, then he'd be forced to either retire or start all over as a flyweight.
But you bring up a good point about Sonnen's career trajectory. He seems to have locked himself into a role that he can't break out of. He's the guy who talks a big game. Trouble is, if you become known as the guy who talks a big game but doesn't win the big fights, you start to seem absurd. Sonnen might not be at that point yet, but he's perilously close.
@benfowlkesmma I'm stoked for this Saturday but if Johnson wins, what does he do next? Are there any other serious threats in the division?
— Ryan Denison (@rdenison13) January 23, 2013
Since the flyweight class is still pretty new to the UFC, it's going to take some time to build a solid stable of contenders. Right now we've got Demetrious Johnson at the top, then the guys he's already beaten – Ian McCall, Joe Benavidez – right below him, and then the guys who are still working their way up, such as John Moraga and Louis Gaudinot. Then, of course, there's the current challenger, John Dodson, whom we shouldn't look past just yet. It's true that there's not a line of clear contenders stretching around the block, the way there is at lightweight, but that shouldn't surprise us this early.
The good news is that, with flyweight all the way at the bottom of the weight class spectrum, there's always the chance that more bantamweights will drop down in the future. Once little guys see there might be a future for them in the UFC, expect to see more of them making a go of it at 125 pounds.
@benfowlkesmma who is truly next for Anderson silva? Weidman? Rockhold? Evans? Jones?#twittermailbag
— Matt Madrigal (@mma_matt88) January 23, 2013
If I had my pick, I'd like to see the champ fight Chris Weidman next. I also wouldn't complain if he did a little champion against champion thing (and not in the Vitor Belfort sense, either) against Strikeforce middleweight titleholder Luke Rockhold. But at this point, I'm not terribly picky. All I ask is that Silva's next opponent is a middleweight who plans to stay a middleweight for the near future. Funny, there was a time when that didn't seem like such an unreasonable request.
@benfowlkesmma Do you think the changes to TUF are big enough to keep it fresh all season? Or will we get used to new FPS before it's over?
— Pat Samson (@samsonmma) January 23, 2013
At least so far I like the new look and feel of "The Ultimate Fighter." Focusing on the fighters' back stories in the first episode made it feel less like a cookie-cutter reality TV show and more like a sports show. Having their friends and families cageside for the first round of fights also eliminated that whole creepy, empty warehouse vibe.
My big concern is that, in a show that's about a bunch of men living in a house with no connection to the outside world, where they do nothing but train, eat, sleep, and fight, there's only so much nuance you can sneak in there. With a show that drags on as long as this one, eventually you have to reach a point where you've told all the stories, jerked all the tears, and all that's left is house hijinks and coaches' feuds. Or, who knows, maybe this is the season where we finally try something new.
@benfowlkesmma Thoughts on Adelaide Byrd judging Aldo/Edgar? Edgar isn't a stranger to close decisions & Byrd has some awful scorecards #tmb
— Paul G (@weepaul7) January 23, 2013
The fact that it's news when Steve Mazzagatti is assigned to referee the same title fight that Adelaide Byrd is assigned to judge is probably not a sign that either currently enjoys the full faith and confidence of the MMA community. One thing that refs and judges have in common in this sport is that if people are talking about you by name, that's usually bad.
@benfowlkesmma What's your take on Dana's response to the whole Rousey/Sandy Hook tweet thing?
— Nicholas Jenkins (@ngjenkins) January 24, 2013
For those who missed it, UFC President Dana White responded this week to questions about the backlash from Ronda Rousey's Sandy Hook conspiracy video tweet by insisting that people were overreacting. Not surprisingly, he used stronger language than that.
Said White: "Everybody has an opinion. She didn't come out and say the thing was a f—ing hoax and s–t. She tweeted something that said, 'Look at this story.' People are f—ing p—–s is the problem."
First of all, a YouTube video isn't a news story. It doesn't go through any fact-checking process or editorial review, which is probably why the people who think everything is a part of some vast conspiracy love it so much. Second, Rousey didn't just suggest people take a look at the video. She referred to it as an "extremely interesting must watch video," which at least implies that she thought the claims made in that video were worth seriously considering. She followed that up with a tweet explaining that "asking questions and doing research is more patriotic than blindly accepting what you're told." In a broad, general sense, she's right about that. But on the subject of "research," I refer you back to the first sentence of this paragraph.
White went on to explain that he thought the Sandy Hook conspiracy video in question was "goofy." That's one way to put it. You could also say it was just plain dumb, and that anyone who could watch that video and come away thinking it was either interesting or something that other people should make time to watch is maybe not the greatest critical thinker on the UFC roster.
White says Rousey is entitled to her opinion, and he's right. It's also true that other people are entitled to their opinions about her opinion. That's how opinions work. I don't think many people are seriously suggesting that Rousey should be fired or officially reprimanded for being taken in by a dumb Internet video. Her job is to fight, so that's the thing people expect her to be good at. If she also happens to believe crazy Internet conspiracies, that doesn't seem like an offense worthy of termination.
It is, however, probably an offense worthy of mockery, which is why Rousey's punishment already fits the crime. When you're a celebrity on Twitter, you have to realize that even vaguely implied support for an idiotic conspiracy theory regarding the very recent murder of 20 children is going to come with some backlash. Some people will see that tweet and conclude that you are not so smart. Others will think you're just being a jerk. Still others will think that you're being incredibly insensitive to the people who were directly affected by this tragedy, and they may make a conscious decision not to support you as an athlete because of it. That's not an instance of people being "f—ing p—–s"; it's an instance of people forming opinions. And, as we know, everybody is entitled to those.
Ben Fowlkes is MMAjunkie.com and USA TODAY's MMA columnist. Follow him on Twitter at @BenFowlkesMMA. Twitter Mailbag appears every Thursday on MMAjunkie.com.


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I haven't posted in a while, so I thought this would be a good post to get back in the swing of things.
One would think that by now people in the U.S. would be experts regarding Iraq. Since George W. Bush talks so much about "bringing freedom" to the Iraqis, saying things like "the safety of America depends on the outcome of the battle in the streets of Baghdad", I assume all law-abiding, patriotic citizens should at least know something about Iraq's culture, its geography, languages spoken, not to mention everything about the daily struggles of the Iraqis. Yeah right, and first thing tomorrow morning, I'm buying a Jaguar for myself and a Porsche for my wife.
It is so incredibly frustrating that the average American is completely ignorant of the current human crisis and refugee situation in Iraq. If this were the 1930's, with no TV, print, or internet, I would understand, but nowadays information is at the tip of the fingertips, one search engine away.
Take this recent article from WireTap Magazine:
Child prostitution is an increasingly widespread phenomenon in Damascus. Out of economic desperation, Iraqi refugee women and girls are forced into these roles. Frequently, women who have lost their husbands or girls who have lost their fathers resort to prostitution to support their families. And sometimes families that have no other financial resources sell their daughters into the sex industry. It is a tragic and horrifying reality.
There are no official figures as to how many of the Iraqi refugees work as prostitutes. But Hana Ibrahim, founder of the Iraqi women's group Women's Will, told The Independent that she puts the figure at 50,000. No one knows how many of the prostitutes are children.
Take a guess if this has EVER been discussed, or at least mentioned, in the mainstream media, with the seriousness this deserves. You certainly won't hear it from the likes of George W. Bush or Dick Cheney. They just don't to talk about the problems, and even if they do, they certainly won't address the causes of it:
The increased trafficking and prostitution is yet another result of the U.S. occupation of Iraq. There are roughly 1.5 million Iraqi refugees in Syria, perhaps 2 million within the Middle East. UNHCR estimates that 50,000 Iraqi refugees arrive in Syria each month. This situation represents the largest refugee crisis in the Middle East since 1948 and is currently the fastest growing refugee crisis in the world. Syria has been accepting more refugees without visas than any other country in the world. On Sept. 11, however, the Syrian government announced new visa restrictions that will sharply decrease the numbers of Iraqis wishing to enter Syria.
50,000 Iraqi refugees each month. That's over half a million last year just to Syria alone. Syria has done a lot for Iraqi refugees, yet you really don't hear much about it. What you do hear is that Syria might get a can of good ol' butt whoopin', shock-and-awe style, if it doesn't do what the U.S. wants. If George W. Bush really cares that much for Iraq's people, then he must be bending over backwards helping Iraqis, right? Wrong:
[…]In a July 2007 press statement, Malcolm Smart, director of Amnesty International's Middle East and North Africa program, states, "The Syrian authorities have responded very positively to the Iraqis' needs, but they and the Jordanian authorities should not be left to bear the weight of this crisis alone." He went on to scold nations who had previously committed to providing financial assistance but had yet to cough up the funds.
But a lack of money is not the only problem. Refugees International underscores that offers from the international community to resettle Iraqi refugees have also been scarce. For example, the United States initially promised it would accept 7,000 Iraqi refugees by October of this year, yet, to date, has accepted only 133. Sweden, which had allowed thousands of Iraqis to resettle, has recently closed its borders to them. The silence of other nations on this issue is deafening.
7,000 measly visas for Iraqi refugees that are fleeing violence, civil war and ethnic cleansing, and of those only 133 have been accepted. Is this the high standard the U.S. currently has in place for the refugees in the very same fucking country it is "liberating"? I mean, give me a fucking break. It's not like the U.S. has never helped refugees before. In 1975, President Ford brought to the U.S. 131,000 South Vietnamese that had worked for the Americans.
We can do a lot better. But I digress. The average American, especially those belonging to that elusive "28%" of the population that still backs Bush in whatever fantasy he spits out of his mouth, doesn't have a clue as to what an average Iraqi refugee has to live with:
According to the UNHCR, Iraqis arrive with three to five months' worth of savings. Due to a scarcity both of resources and of housing, they live in overcrowded neighborhoods outside of Damascus, such as Jeremana, often cramped seven to a room with few furnishings. Iraqis are not allowed to work in Syria, so when their funds run out, they are unable to support themselves. Consequently, many work illegally. Yet these jobs are difficult to come by and poorly paid, and workers frequently face discrimination. A report published by UNHCR and UNICEF last year states that an estimated 450,000 Iraqis in Syria "face aggravated difficulties" related to their "ambiguous legal and unsustainable income." As their savings dwindle, the situation of Iraqi refugees is bound to deteriorate further. Sybella Wilkes, the UNHCR Regional public information officer in Damascus, says that "64 percent of the people who have arrived here have run out of savings."
Bassam Alkadi, of the Syrian Women's Observatory, agrees that the economic desperation is leading to an increase in prostitution. "The standard of living for Iraqis," he says "has gone downhill very quickly."
Yet according to Dubya, freedom is on the march. Sometimes I wish I were more eloquent so I can convey my thoughts and emotions better, but such is not the case here. The Iraqi refugee crisis is something I, along with others that truly give a damn about human rights, have been discussing since before the U.S. invasion of Iraq. One of my main gripes, though, is the hypocrisy that people have towards all of this. They care about the Iraqis, yet don't want or don't care to find out what's really happening. It is all horseshit. Just admit it – this war has nothing to do with WMDs (guess who still believes that nonsense), democracy, or human rights. The average American does not understand or care much about human rights, and neither does Dubya.
Who are you going to believe, me or the president of the United States? Hint: I have been known to be right on occasion.


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Now that Rep. Spencer Bachus reintroduced his bill to establish an SRO for investment advisors (as Melanie Waddell reported on AdvisorOne on April 25), the focus of the re-reg debate has returned to whether FINRA should be that SRO, and whether it should apply SIFMA's guidelines as a uniform fiduciary standard for brokers and advisors. To sort it all out, I had a conversation with my friend Knut Rostad, compliance officer at Rembert Pendleton Jackson, and founder of The Institute for the Fiduciary Standard.
The conversation started when I asked Knut how he felt about SIFMA's watered-down fiduciary standard. He replied by saying that calling it a "watered-down" version was completely misleading. The truth, he said, is that SIFMA does not support a fiduciary standard for brokers, or at best, supports it in name only. Consequently, using that term only promoted SIFMA's fiction.
Despite my defense that "watered down" is the usual term we apply to laws or regulations that have had their original teeth removed, and that calling SIFMA out and out liars on the subject may tend to marginalize one as a melodramatic, Knut made a compelling case that such strong language is warranted. I'll let you be judge.
Using the PowerPoint from his recent speech at the fi360 conference in Chicago, Knut detailed how the SIFMA standard differs from key elements in the fiduciary standard that RIAs are currently subject to under the Advisers Act of 1940. Here's what the side-by-side comparison looks like:
Product Recommendations
Advisers Act: Recommendations are made in the client's best interest.
SIFMA: Recommendation is suitable; no best-interest due care.
Advisers Act: Undermine unbiased advice; must be avoided at all possible.
SIFMA: Need not avoid; may benefit client; champions conflicted advice.
Fees and Expenses
Advisers Act: Expenses must be controlled, with higher than usual costs in the client's best interest.
SIFMA: Silent.
Scope of Obligation
Advisers Act: At all times when providing investment advice; continuous, based on relationship of trust and confidence.
SIFMA: Limited to recommendations about the purchase or sale of a security, or discretionary decision; sporadic, based on account, discussion topic, or contract.
Disclosure of Conflicted Advice
Advisers Act: Effectiveness for investor; advisor is responsible to ensure the client fully understands disclosure; the transaction in question must meet the best interest standard.
SIFMA: Efficiency for broker/dealer; investor is responsible for understanding disclosure.
As you can see, there is a world of difference between RIAs' current standard and the one proposed for brokers by SIFMA. Is it then fair to say that SIFMA does not, in fact, support a fiduciary standard? Well, it certainly doesn't support a '40 Act standard, which is the requirement for a broker standard under the Dodd Frank Act, that would put advisors and brokers on a level playing field.
If you don't like the work "lieing" let's just say that SIFMA is dissembling—because it certainly isn't supporting any fiduciary standard that I've ever seen.


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Steunenberg Frank -- [Date of Birth] 06/10/1911, [Service Number] 000237237, [Date of Enlistment] 11/02/1932
ARC Identifier 2499484 / Local Identifier MC24013041
Textual Records from the Department of Defense. Department of the Navy. U.S. Marine Corps. Personnel Management Division. (ca. 1947 - )
NARA's National Personnel Records Center (Archival Operations Branch), St. Louis, MO
File Unit from Record Group 127: Records of the U.S. Marine Corps, 1775 - 9999


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FOXBOROUGH, Mass. – The New England Revolution has signed forward Chad Barrett and defender Bilal Duckett. Both players will travel with the team to Tucson today for the next stage of preseason training. Further details of the signings will not be released.
Barrett, whom the Revs drafted in Stage 2 of the 2012 MLS Re-Entry Draft, will officially be added to the team's roster upon receipt of his International Transfer Certificate. Duckett joins the team on a free transfer from the Harrisburg City Islanders, where he spent the 2012 season.
"We're pleased to reach agreements with Chad and Bilal," Revolution General Manager Michael Burns said. "Having faced Chad many times, we're very aware of the type of competitor he is and the determination he brings to the field, and we're looking for him to bring that to the field for the Revs now. With Bilal, we're bringing in a tall, physical defender who gives us depth and versatility along the backline. Having him in camp last fall and this preseason has helped his assimilation into our system."
Barrett, 27, has seven seasons of MLS experience after entering MLS in 2005. He has scored 42 goals and added 27 assists in 192 career appearances with Chicago (2005-08), Toronto (2008-2010) and LA (2011-12). Most recently, he was on loan from the Galaxy to Valerenga of Norway's Tippeligaen, where he made five appearances and recorded one assist through the end of their 2012 season.
The Chicago Fire drafted Barrett as a Generation adidas player with the third overall pick in the 2005 MLS SuperDraft after he played two seasons at UCLA. He is a former member of the U.S. Under-20 team, and earned a call-up to the full U.S. National Team on June 22, 2008, against Barbados in a FIFA World Cup Qualifier.
Duckett, 24, spent the 2012 season with the Harrisburg City Islanders of USL PRO. He made 19 appearances as a defender as the team advanced to the USL PRO playoffs. Prior to signing with Harrisburg, Duckett played one season with Vancouver Whitecaps FC after the Whitecaps drafted him in the third round (37th overall) of the 2011 MLS SuperDraft. He made four appearances, including two starts, as a rookie with Vancouver.
Duckett played collegiately at Notre Dame, where he started 40 of the team's 42 matches in his junior and senior years.
Excited to officially join @nerevolution... It's been a long journey. Thanks to everyone who helped me get here. Y'all are all a blessing— Bilal Duckett (@bilalduckett) February 11, 2013
Jersey Number: 9
Position: Forward
Date of Birth: April 30, 1985 (San Diego, Calif.)
Hometown: Beaverton, Ore.
Height: 5-11
Weight: 185 lbs.
Previous Club: Valerenga (NOR)
College: UCLA
Nationality: USA
How Acquired: Selected by the Revolution in Stage 2 of the 2012 Re-Entry Draft on Dec. 14, 2012; signed by the Revolution on February 11, 2013
Follow @CBarrett19
Full name: Kevin Bilal Duckett
Jersey Number: 16
Position: Defender
Date of Birth: January 9, 1989 (Macon, Ga.)
Hometown: Macon, Ga.
Height: 6-2
Weight: 170 lbs.
Previous Club: Harrisburg City Islanders (USL PRO)
College: Notre Dame
Nationality: USA
How Acquired: Signed by the Revolution on February 11, 2013
Follow @bilalduckett


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More Famous Last Words
From: Diana Oertel
Here are a few more "last words" for your consideration.Yes, you do look fat in those pants.
You shoot first, Mr. Cheney.
I designed it myself.
No, I've never seen Jaws. Why do you ask?
Did I disconnect the what?
You need braces, Mr. Dracula.
Who ever heard of an ostrich killing a man?
I know these woods like the back of my hand.
So... howdya get the name "Killer"?
You call that a watchdog?
Look... he's eating out of my...
Hey, I'm the Croc Man!
Is that a real gun?
Relax. I minored in chemistry.
Nobody actually reads the instructions.


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Volvo has an image problem. But that's nothing a 508-horsepower custom sedan with a $300,000 price tag can't remedy.
Sure, there's a surprising amount of spunk in their $44,000, all-wheel-drive S60 R-Design, a 325 horsepower stab at the sports sedan ideal epitomized by the BMW 3 Series. But the Swedish (by way of the Chinese) automaker's historic obsession with safety makes it all but impossible for them to make serious in-roads to sports car fanatics.
So what to do? Tap into Volvo's little-known racing heritage and leverage the engineering skills of an outside party.
A boutique tuning company called Polestar' which has served as Volvo's official race partner since 1996 and provides warrantied performance tweaks to their factory offerings' Frankensteined an S60 by building a one-off super sedan for an unnamed (and rather well-heeled) Volvo aficionado (yes, they exist).
Since project car zero, five more of these bespoke beasties are being built in order to show exactly how edgy Volvo can be when they set their sensible Nordic minds to it.
"The difference is actually quite big," Polestar's North American sales manager Andreas Naeslund says, referring to – of all things – the S60 Concept's paint when looking at the comparatively pedestrian R-Design sedan. For the record, the "Rebel Blue" hue available from the factory is imperceptibly darker than this particular shade, but that really illustrates more about the Swedes than any cultural guidebook will tell you. These guys revel in nitty-gritty details, and this extra special S60 is rolling, snorting proof.
Weighing some 220 pounds lighter than stock, thanks in part to carbon-fiber bodywork, the Polestar's pavement-devouring personality can mostly be credited to the radically massaged motor lurking beneath the hood. It's based on the same 3.0-liter inline-six cylinder block as the standard car, but that's where the similarities end. A cannon-like intake manifold composed of CNC milled aluminum feeds an engine fitted with everything from forged connecting rods to a massive Garrett 3171 turbocharger. Extra lightness is derived from stuff you can't get in the U.S., like a Getrag manual transmission gearbox that sheds about 90 pounds from the S60's not-entirely-svelte curb weight.
Apart from subtle strips of Alcantara and the otherwise unavailable three-pedal setup, there's little to betray this midsize sports sedan's exotic underpinnings. The six fires up with a guttural hum, and there's a perverse pleasure when you realize the green/yellow/red lights projected onto the windshield and originally used for Volvo's City Safety system have been modified to display engine RPMs. Samuel Hubinette would approve.
It's been a long while since Volvo was the naughty voice whispering in my ear.The Polestar sits wider and lower thanks to swollen fenders and dropped suspension. A flex of your right foot coupled with the release of the heavyish clutch yields a forward push that doesn't feel exceptionally swift. At least not yet. But climb through the rev band, and that demonstrative exhaust howl suddenly becomes an accurate signifier for what's about to unleash from those six eager cylinders. The turbocharger spins up once the engine passes 2,500 rpm, assisting acceleration with a mighty whoosh and an urgent shove, which is allegedly capable of launching this midsize sedan to 60 mph in only 3.9 seconds.
I've been instructed to stay on the mellow side of the clutch, as its mounting hardware has been taxed by some of my lead-footed colleagues, but it's just as well; here on Angeles Crest Highway, some 4,000 feet above Los Angeles, a light snowfall is dusting the road, and the summer-rated Michelin Pilot Sports aren't quite up to the task of taming these sinewy bits.
But there's a certain amount of shame that goes with tiptoeing around a car's eager spirit due to something as trivial as the weather, and the S60 responds to my throttle input with rambunctious, unbridled charges towards redline, whereupon the dashboard light show comes in full swing, illuminating the progression of incandescents like a dragstrip Christmas tree. The roll-on acceleration is otherworldly, and the somewhat notchy transmission, which has been programmed to blip the throttle with rev-matched downshifts, obliges with a cabin-filling boom as the S60 is tossed into a corner.
We're not quite going fast enough to feel the Haldex-equipped driveline's limited-slip rear differential, which spins the rear wheels 1.5 percent faster than the fronts in order to essentially shove the car through a corner, thereby avoiding the annoying tendency of most Volvos to understeer their way through a bend. But we're certainly going quick enough to feel that this firecracker of a sports sedan has more than a trace of supercar blood coursing in its royal blue veins.
Power is routed to the wheels with effortless authority, the remote reservoir-equipped Öhlins suspension conveying every last nook and cranny of these tar-snaked roads, while the six-piston Brembos leave nothing to chance when it comes to deceleration. Most importantly, this Volvo feels alive, egging you on to find out if those Michelins are really as grippy as they seem.
It's been a long while since Volvo was the naughty voice whispering in my ear, but heck, if this ultra low volume proof of concept can't stir my adventurous side, I don't know what will.
Brawny, frisky and hot-rodded to within inches of its otherwise workabout life, this souped-up S60 makes a stunning case for genetic mutations developed deep in the bowels of the race shop. Its ultra-rare origins lend it an impossibly high price tag, but as a whimsical look at how far Volvo could go with this whole ultra high-performance thing, the S60 Polestar Concept certainly gives us hope for a saucier future that's more Elin Nordegren than Swedish Chef.
All photos: Basem Wasef


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Marco Rubio was also in good spirits this morning after the twitter frenzy surrounding his quick drink of water during his response to President Obama's State of the Union address last night. "I needed water, what am I going to do" Rubio told me this morning on "Good Morning America" while pulling out a bottle of water and taking a sip. "God has a funny way of reminding us we're human," he said.
The Florida senator took a more serious tone when responding to the president's call for Congress to keep the government open and uphold the full faith and credit of the United States.
"What really threatens to shut down our government is the $16.5 trillion debt and no serious plan to deal with it, including last night when the president seems to believe we're halfway to our goal of reducing our debt to an acceptable level," Rubio told me. "I mean no one is going to think that that is realistic when you start to look at the numbers. That's the real threat to shutting down our government. No one here is talking about shutting down the government."
Rubio had strong words for the president regarding the impending budget negotiations as lawmakers in Washington work to reach an agreement to avert the across the board spending cuts that are currently scheduled to go into effect on March 1 st.
"He actually came up with that," Rubio told me, referring to the upcoming cuts, known in Washington as the sequester. "It originated in the White House, the idea of these automatic cuts that specifically hit defense and the military and now he's going around saying that we have to get rid of them. We may but don't go around acting like you have nothing to do with it. It was your idea."
In our interview this morning Rubio also reiterated his commitment to passing a comprehensive, bipartisan immigration reform deal that includes a path to citizenship, something both he and the president addressed last night in their respective speeches.
"I'm part of that work group and we laid out our principles and I remain committed to those principles. That's what we're working on," he told me. "We're working on turning those principles into a bill people can support."
"One of those principles is that ultimately it's not good for America to have 11 million people who will never have a chance to become fully invested in the American dream," Rubio said. "There's going to have to have be a process to get there. They're going to have to have a work permit first and the right to ultimately earn a green card and obviously once you have a green card you're five years away from being a citizen."
Source: ABC OTUS NEWS
{Matzav.com Newscenter}


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Difference between revisions of "SpreadsheetML"
m (→Development)
|Line 111:
|Line 111:
| Label ranges [[http://www.bettersolutions.com/excel/EFC133/LE824631331.htm reference]] || || skipped || MS Office 2007 seems to have dropped support for this feature.
| Label ranges [[http://www.bettersolutions.com/excel/EFC133/LE824631331.htm reference]] || || skipped || MS Office 2007 seems to have dropped support for this feature.
| Data validation || || ||
| Data validation || || ||
| Web queries || || ||
| Web queries || || ||
Revision as of 19:48, 10 May 2007
SpreadsheetML is the XML format used by Microsoft Excel 2007 and that is part of the Office Open XML specification.
- 1 SpreadsheetML Basics
- 2 Sample Files
- 3 Implementation Strategy
- 4 Code Organization
- 5 Development
- 6 See Also
SpreadsheetML Basics
A SpreadsheetML document is described at the top level by a workbook part ( /xl/workbook.xml ). The type of the work book type is
The workbook part contains document's metadata and one or more sheets. Each sheet can be a worksheet, a chart sheet, or a dialog sheet.
Both strings and formulas are stored in shared tables to avoid redundant storage and speed file I/O's.
Sample Files
Convenient locations to download sample files are here
Implementation Strategy
Eventually, the code handling SpreadsheetML import will merge with the existing Excel binary filter. As such, the new code needs to be designed with this in mind. It's always desirable to understand how the existing binary filter works when implementing the XML filter to make the future merging work less painful.
Code Organization
Source files for handling the SpreadsheetML format are located in inc/oox/xls and source/xls under module oox. A good place to start tracing the code would be ExcelFilter::Import and follow the calls it makes.
A substream in the XML package is called "fragment", and each fragment has an associated *fragment.hxx header file. For instance, the code for loading of the workbook.xml fragment is found in workbookfragment.hxx, and so on.
A nested element is called "context", and, like the fragments, each context has an associated *context.hxx. For instance, the code for parsing the <sheetData> element is found in sheetdatacontext.hxx.
The term workbook in this context refers to an entire document which includes worksheets and other document metadata, whereas the term worksheet refers to each individual sheet in the workbook.
The existing binary Excel filter is located in sc/source/filter/(inc|excel)/xi(page|view).(c|h)xx. The XclImpTabViewSettings class handles importing sheet's view settings, which corresponds to worksheet/sheetViews context in the XML format.
The UNO interface code is found in sc/source/ui/uno.
Global data
Workbook-wide global data are stored in GlobalData (struct), and handled by GlobalDataHelper (class) which holds reference to the GlobalData instance. All major classes should be derived from GlobalDataHelper to ensure availability of globals in all places.
GlobalData holds reference to ImportBase instance in order to be able to create new fragment handlers.
Different buffers hold the imported data from the fragments if it is needed later, e.g. the SharedStringsBuffer (sharedstringsbuffer.hxx) and the StylesBuffer (stylesbuffer.hxx). These buffers are always part of the GlobalDataHelper.
GlobalDataHelper (class)
It's important to be familar with the member methods of this class, because they are also available in most of XLSX import classes.
Handling Fragment
WorkbookFragment (class)
Handles loading of workbook.xml fragment. It loads the associated relationship file (xl/_rels/workbook.xml.rels) in the constructor.
Handling Context
In most cases the fragment handler will handle all nested contexts by itself to increase performance. For this, some helper classes have been implemented that do all needed work to deal with nested contexts (ContextHelper, FragmentBase, and ContextBase respectively in contexthelper.hxx, excelfragmentbase.hxx, and excelcontextbase.hxx). In general, for implementing a new fragment or context handler, the interface of the ContextHelper class from contexthelper.hxx has to be implemented. The classes FragmentBase (excelfragmentbase.hxx) and ContextBase (excelcontextbase.hxx) already provide default implementations of all virtual functions, but a derived class is free to implement them as well.
Relation (class)
Holds three string data for ID, Type and Target (need more info).
AddressConverter (class)
converts strings to addresses and ranges, and tracks invalid addresses (e.g. a not-importable cell at address ZZZ1000000). Later, this information will be used to generate a "Imported document contains data outside of sheet limits" warning box after loading. Header: addressconverter.hxx
UnitConverter (class)
provides basic unit conversion, including font dependent stuff such as calculating column width from a specific number of characters. Header: unitconverter.hxx
|Framework, fragment handling
|Workbook, worksheet fragment, sheet names
|in progress
|do not insert default sheets (issue 74668)
|Simple cell contents (values, strings)
|in progress
|error cells
|Shared strings fragment
|Styles fragment
|Simple cell formatting (alignment, protection, borders, fill)
|Builtin number formats
|in progress
|missing locales (issue 29949)
|Font handling for cells
|in progress
|asian/complex scripts (issue 74754)
|Cell styles (names, formatting)
|Column settings (format, width, outlines)
|in progress
|outlines, hidden, column width from font (issue 75447)
|Row settings (format, height, outlines)
|in progress
|outlines, hidden, row borders (issue 74667)
|Rich text in cells
|Scheme fragment, scheme colors
|Cell formulas, array formulas
|in progress
|almost ready to be committed.
|Conditional formatting
|on hold
|blocks on formula parser.
|External references/links
|in progress
|parsing of externalLink fragments complete. The external link information is stored in ::oox::xls::ExtRefBuffer.
|Print ranges, builtin defined names
|on hold
|blocks on formula parser implementation because a defined name can be any cell formula.
|Page/print settings
|in progress
|waiting on header/footer task to be completed.
|in progress
|Header/footer height calculation still pending.
|Column/row breaks
|Sheet/document view settings
|in progress
|not possible to set view settings during import; probably needs to create a buffer class to store imported view settings, and apply them after the import.
|Cell hyperlinks
|because a cell hyperlink is a in-cell text field object in Calc, as opposed to a cell property in Excel, a hyperlink will not get imported when the cell is a value cell.
|Label ranges [reference]
|MS Office 2007 seems to have dropped support for this feature.
|Data validation
|on hold
|requires formula parser.
|Web queries
|Pivot tables
|Drawing objects
|OLE objects, form controls
|Auto filter, user filter
|Change tracking
External References
- xl/workbook.xml contains externalReference tags that references relationship items in xl/_rels/workbook.xml.rels by rID.
- xl/_rels/workbook.xml.rels contains path(s) to external link fragments, that are usually xl/externalLinks/externalLink*.xml.
- xl/externalLinks/externalLink*.xml contains summary content information of the external book being referenced. It should provide enough information to display external cell's content. It also contains reference to the path to the external file by rID.
- xl/externalLinks/_rels/externalLink*.xml.rels contains the path to the external file, stored by rID.
Inside a cell that contains an external cell reference, the format is given
as formula.
Page Settings
Refer to class XclPageData which is the data structure used by the existing binary filter. Here is the page for Calc's sheet properties.


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BILL NEALA super… Super Bowl Special Review:10 Hold up… Wait a minute… Oh man, get on your feet and jam… We don't need no music. We got soul… If you ain't gonna party, take your dead xx home… The roof, the roof, the roof is on fire…We don't need no water let the xx burn… Awwww Sooki Sooki now!! Yep, all of them. You can use all them good old par-tay shout outs and it won't come close to what Beyonce did… Are–You–Kiddin–Me? Did you see her? Did you see them? Did you see her?? There will be an emergency meeting called with the "Top Ten Committee" cause somebody's "body" has got to go! Ms. Beyonce has just moved into the No. 1 spot. Sorry Halle and J-Lo. Step it down one. By the way, she gets 4 stars—4 basketballs—hell—4 cucumbers, I don't care… it's over!!!:09 You can't discount the emotional ride. Just ask Hines Ward how bad they wanted to win for Jerome Bettis. The Ravens rode the Ray Lewis emotional horse all the way to the Super Bowl title. Well played Ray, well played. Deer antler juice and all!:08 Did ya'll see Beyonce?!? Oh my bad. Back to the game.:07 Don't get me wrong. Emotion is good and talent is essential, but it sure doesn't hurt to have a no-call when Jimmy Smith assaulted Michael Crabtree in the end zone. That was a flag, no doubt about it. C'mon ref!:06 Joe Flacco named MVP… I am ok with it, but a lot can be said for Jacoby Jones' more than 300 collective yards, including the 108 yard kick-off return, longest in Super Bowl history.:05 The night the lights went out in New Orleans. Call it a desperate attempt by the 49ers to slow the Ravens machine down. Call it bad luck in the bayou, but if you ask me, that was Miss Rudolph putting a "root" on somebody and the stadium just got in the way.
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June Jamrich Parsons is the author of 'New Perspectives on Microsoft Excel 2010, Introductory (New Perspectives Series: Individual Office Applications)', published 2010 under ISBN 9780538742399 and ISBN 0538742399.[read more]
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Hooked On Driving - Northeast @ Pocono Raceway
Hooked On Driving - Northeast
Thursday, July 30, 2020
Pocono Raceway, Long Pond, PA
ATTENTION! Your web browser is either very old or portions of MotorsportReg.com are being blocked. As a result, some things on this and other sites may be out of place or look broken. Before you try and register for events, learn how to correct it.


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Nikki Thompson, also known as Nikki and The City, is an urban media expert from Chicago who loves to travel and report on issues that impact different cultures and communities. Nikki's work has been featured on Huff Post LIVE, Jet Magazine, and ESSENCE just to name a few. Visit her blog at www.nikkiandthecity.com.
Recent Stories
Why All Black People Should Visit Africa
I was 23 years old when I took my first trip to Africa, and if you ask me my trip occurred a little too late. It should have happened as soon as I developed comprehension and understanding. It should have happened before the "African booty scratcher" jokes became funny to me, and before Africa became the dark continent in my mind. However, thank goodness it happened. After visiting the beautiful country of Zambia on two different occasions, I'm convinced that every Black person should visit Africa at least once. It will change your entire life. It most definitely changed mine.
Is It Necessary To Celebrate Black History Month?
We don't have a White history month, so why is there a Black history month? Is It Necessary to celebrate Black History Month? Read on...
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This new era of beauty among Black women celebrates the mind. It celebrates our beautiful spirits, our beautiful struggles, and our beautiful hopes.
Why We Need Another Civil Rights Movement
As a child I would often watch old clips of the Civil Rights Movement and desperately wish I could have participated. The focus and eloquence of Dr. King inspired me. The courage of the children challenged me, and the unity of Black people was something I'd yet to witness in my generation. My soul longed for the days when Black people didn't sit around and hope for change, but actually fought for it to happen.


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Reality Television star Scott Disick and his 3-year-old son Mason were seen dining at Sugarfish in Calabasas, CA on Wednesday (September 11).
Scott Disick and his sweet son Mason
Posted by Alisa on Thursday, September 12, 2013 / Comments: (0)
Alessandra Ambrosio and son Noah
Posted by Alisa / Labels: Model Moms / Comments: (0)
Model Mom Alessandra Ambrosio was seen running errands with her 1-year-old son Noah in Brentwood, CA on Thursday (September 12).
Louis C.K. and his daughter Mary make a cute pair
Comedian Louis C.K. and his adorable 5-year-old daughter Mary were seen sharing a snack on their way home from school in New York on Wednesday (September 12).
Kate Middleton's first public appearance since giving birth to baby George
Kate Middleton attended her first carpet event since becoming a mum to baby George on July 22, 2013. The Duchess of Cambridge looked slim and healthy as she accompanied her hubby Prince William to the Tusk foundation gala at The Royal Society in London on Thursday (September 12).
Miranda Kerr's smiling sweetheart
Posted by Alisa / Labels: Model Moms, Orlando Bloom and Miranda Kerr / Comments: (0)
Miranda Kerr took her beautiful 2-year-old son Flynn to the American Museum of Natural History in New York City on Wednesday (September 11).
Penelope Cruz's Slim Post-baby figure
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Penelope Cruz showed off her post baby figure while on holiday in Spain with her husband Javier Bardem and their children Leonardo, 2, and Luna, 2 months.


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Living Like a Native in Rio de Janeiro
Mingle with the locals in Rio de Janeiro and have a true experience of the city
Rio de Janeiro is considered one of the party capitals of the world. World Famous for the Rio Carnival, its Samba music and pristine beaches, there is more to Rio de Janeiro than just these facets. To get to know the real Rio it will help to live like a native. Brazilians are welcoming of tourists and feel privileged to help and show the city around, so as also being careful of who you are with try to keep an open mind as you can make friends with the locals and have a true experience of the city.
Before you go
The native language of Rio de Janeiro is Portuguese, not Spanish like many believe. Try and take some lessons in Portuguese for a few weeks before you arrive. Your knowledge of the language will get you into areas where no one speaks a foreign language and all the locals hang out.
Live Like a Native
To live like a native, do not book a room at one of the tourist hotels that line the beaches. Instead look for a bead & breakfast or an apartment for rent located in a residential neighborhood. Or consider swapping homes with someone in Rio de Janeiro. Just be sure your accommodations are in a safe neighborhood.
Look like a Native
To live like one of the locals you must look like one of the locals. First, get yourself a pair of Havaiana flip flops. Everyone wears them and most locals have 3 or 4 pairs. Men usually wear speedos to sunbathe and others wear boardshorts, mostly surfers. Women wear the famous brazilian bikinis that tend to be smaller but have various beautiful designs, make sure you buy one. Covering up to go home is recommended, the ladies at the beach use something called ' canga'. The canga is also useful to be laid on it. Cangas are sold by vendors all over the beach. They are colorful and are usually of Rio sites such as the Christ statue, make sure you get one as they make a great souvenir.
Act Like a Native
Eat lightly at night, tapas or appetizers are the norm for the locals. Ordering a big meal at night will peg you as a tourist. Instead, eat your largest meal at lunch. Ask the locals where they go to dine, drink and dance and be sure to frequent those places.
Hiring a local tour guide is another sure way to live like a Carioca. A native guide can show you all the attractions as well as the best local hot spots. Another really nice way to get to know people of the city is through couch surfing. This website gives you a chance to meet people from all over the world.
Most importantly have a positive attitude, Rio is known for being a relaxed place, and things might not go the way you expect so try to make the most of every experience, that's how natives go on with their lives, if things can't be changed they just take it as an opportunity to have fun.


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Justice Department OKs Michigan redistricting plan
LANSING, Mich. (AP) -- Michigan Attorney General Bill Schuette says the U.S. Justice Department has cleared the state's redistricting plans as required by the Voting Rights Act.
Michigan and 15 other states need federal approval for some or all redistricting plans.
The Republican-controlled Legislature approved the plans for redrawing U.S. House and state legislative districts, and Republican Gov. Rick Snyder signed them.
In November, Republican Schuette asked U.S. District Court in Washington, D.C., to approve the plan, and the Justice Department said Jan. 12 it doesn't object.
On Dec. 8, labor and civil rights groups sued to challenge new boundaries for Detroit seats in the state House.
The suit says the new map forces black incumbents to run against each other and dilutes the political representation of Hispanics. That case continues.


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Today we found articles on things you can do with eggs besides eat them, space saving ideas for a small closet, and the best online subscriptions for buying books.
We don't know exactly what 2017 will bring, but we do know that these grocery items will cost less!
The Easter Bunny brings a wealth of knick-knacks and treats. Stuck wondering what to do with those goodies post-Sunday? Repurpose them!
This list of egg-ceptional evening egg recipes doesn't include frittatas and quiche — but you will find egg-citing new ways to bring eggs to the dinner table.
Breakfast… for dinner? Go ahead, everyone does it, and you will more than once with these delicious recipes to choose from.
How many ways can you make an egg? Here are six techniques for making egg-cellent eggs every time, from scrambled to sunny side up.
If you're looking for filling, inexpensive protein to anchor your meals, there are more options than you may think (and they're delicious!).
If you've thought about getting your own set of fowl, this starter guide will have you well on your way to fresh eggs and friendly wake-up calls.
You know that they're edible; now learn why these frugal sources of protein are incredible.
Once upon a time, eggs came in medium and large, white and brown, and which one you chose wasn't of much consequence. Nowadays, this cheap source of nutrients and protein comes in
Have you ever eaten an egg from a chicken that lives outside, eating bugs and worms and grubs instead of just chicken feed? You notice the difference as soon as you crack the she
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PJ1 Sandable Primer White (18-PRMW) 57-10181 by PJ1
PJ1 Sandable Primer White (18-PRMW)
11oz Aerosol Paint Primer
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Shipping Information
Most orders are shipped from our main warehouse in Trenton, Michigan. However, we also ship from nine other warehouses across the United States and we may, due to parts availability and your location, ship some or all of your parts from our satellite warehouses. If your order is split and ships from multiple locations you will not be charged any additional shipping charges for this service. The shipping charge you are quoted when you place your order is all you will pay - even when shipped free.
We use UPS, USPS and FedEx to deliver your packages. The carrier and service that we select depends on distance, delivery schedule, cost, and parts stocking location as well as a number of other factors.
This product can expose you to chemicals which is known to the State of California to cause cancer/birth defects or other reproductive harm.
For more information go to www.P65Warnings.ca.gov.


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06 December 2012 | News | By BioSpectrum Bureau
Bluechiip, MiTeGen sign licence deal for crystallography goniometer bases (cryopins)
Singapore: Bluechiip signed a license agreement with US-based high-technology manufacturing company, MiTeGen, for tracking cryopins. The joint development, collaboration and license agreement with Bluechiip allows MiTeGen to integrate the former's tracking technology into the cryopins.
MiTeGen manufactures and sells cryopins to organizations like the Australian Synchrotron, for which Bluechiip has just completed a project, as well as other synchrotrons around the world. The agreement allows MiTeGen to develop with Bluechiip, and sell the enhanced product. This adds a further product to Bluechiip's range and another revenue stream as the company moves into the commercialization phase.
MiTeGen, which is based in New York, US, designs, manufactures and distributes products for crystallization, crystallography and x-ray diffraction of proteins, viruses and small molecule and inorganic compounds. MiTeGen supplies crystallography goniometer bases, which are also commonly referred to as cryopins, for crystal mounts that are used in synchrotrons. MiTeGen's customers include academic, medical, pharmaceutical, government and industrial laboratories in more than 40 countries.
Mr Brett Schwarz, managing director of Bluechiip, said that, "We are confident that the agreement with MiTeGen will lead to better products and greater sales for both organisations, as well as prove the 'platform technology' nature of the bluechiip tracking technology."
Mr Robert Newman, CEO, MiTeGen, said that, "MiTeGen has a history of bringing cutting-edge sample handling innovation to crystallographers. We are excited to continue this tradition by partnering with Bluechiip to bring their sample tracking technology to beamlines and crystallography labs worldwide. The bluechiip technology offers numerous advantages over traditional bar-coding of bases and is extremely well suited for cryogenic conditions, as well as room temperature studies."


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Talk about retail therapy. 25 days after news broke that he'd entered a substance-abuse program, fashion designer Marc Jacobs was seen strolling into West Hollywood's Fred Segal store with professional rock star-muse (and possibly pregnant) Amanda de Cadenet. And it looks like Marc scored himself some stylish parting-gifts during his get-sober stint: A killer tan and a tote bearing the name and logo of Arizona's Sierra Tucson treatment center. Could Sierra Tucson bookbags be the start of a new trend? Copycat fashionistas and Marc obsessives, you can get your own such tote here for the very un-Marc price of $9.95. Glad we can be of help.
Sierra Tucson Store - Keepsakes [SierraTuscon]
Related: Breaking: Marc Jacobs In Rehab [Fashionista]
[Image via Splash, 4/7/07]


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Asked by:
How to sync between different platforms
I have a project with the following requirements:
- There must be a Desktop-based (preferably WinForms) client and a WP7-based client.
- Both will use the same data model
- The clients need to be able to sync with each other, and each is an OCA .
- The clients are completely independent (ie. can run at different times, and need not know the other even exists).
- The database is located on a remote server
As far as I can tell, the best way to do this is to use Sync Framework. Using the tools provided in the 4.0 CTP release, I have a web service that works great for the WP7 client, but cannot find an example of how to use this kind of service with a Windows Forms application.
Temporarily, syncing the windows forms application directly with the server (violating the remote server requirement), is acceptable, but I have not been able to make this work either (using the local database cache provided with Sync Framework 2.1). I can generate the files, but whenever I call "Synchronize" from the SyncAgent, I get a "MissingSessionVariable" exception.
I am using SQL Server 2008 and Visual Studio 2010 as my development tools, and C# as my development language.
All replies
I suggest you use the Sync Toolkit instead of the 4.0 CTP. The Sync Toolkit is what has become of the 4.0 CTP. You can download the bits here: http://code.msdn.microsoft.com/Sync-Framework-Toolkit-4dc10f0e
Now, the Local Database Cache wizard and the Sync Toolkit are using a different of set of sync providers and they track changes differently.
I suggest for your WP7-based client, you use the Sync Toolkit (which is actually built on top of Sync Framework 2.1).
For your WinForms app, use the full Sync Framework 2.1 using WCF and have both of your WP7 and WinForms app sync to the same scope on the server.
you can find a sample WinForm app here:
I'll try the code samples you provided; I assume that they will connect to the OData based WCF service correctly? Also, the last time I tried using the full Sync Framework (albeit without WCF) I always got a "MissingSessionVariable" exception when I called Synchronize(). Can you think of a reason that would be happening, or a way to fix it?
I previously downloaded the Sync Toolkit, when I built it it looked like it was just the CTP tools (SvcSyncUtil) with some client examples. Were there any other differences that I should be aware of? (Note: when i built and ran the tool project, it crashed...).
Thanks for the help.
the 4.0 CTP never made it a v4. MS instead release the CTP 4.0 bits as the Sync Toolkit. So, the Sync Toolkit is essentially the released bits of the supposedly v4.0.
The Sync Toolkit is primarily built for clients that can't have the full Sync Framework SDK/Runtime (SilverLight, WP7, iPhone, HTML5, etc...)
The Sync Toolkit service on the server side is still using Sync Framework 2.1. It's just exposing the endpoint as OData.
With regards to the error you got, how did you configure it? i'm guessing must be some wrong config somewhere.
Note that the Local Database Cache Wizard providers is totally different from what Sync Toolkit is using. So even if you get it running, you will end up with two totally different synchronization components (e.g. duplicate change tracking)
When I got the error, it was a default configuration. SQL Server 2008 with change tracking for the server (direct ADO.NET connection, no WCF or anything), SQL Server Compact for the local database cache. I set up a timer on my form to call Synchronize, and every time I would call it I got the exception (this was without any changes being made to any data).
I'm guessing there is something I need to add to the configuration, I just have no idea what.
Thanks again for the help.
yes, I tried regenerating the code and was always using incremental changes.
I looked at the code samples you suggested, and they definitely look like what I need. The only problem I am having is difficulty in locating the database specific fields that I need to modify for my actual schema. Is there a tutorial on how to use/modify this code for any use?
I'd like to use SQL Server Express so I can connect to it using Entity Framework.


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About this paper
In the pharmaceutical industry, the overarching goal is to bring drugs and devices to market faster that improve health outcomes for patients. But what happens once those drugs are in the market and clinical trials conclude? Real world evidence (RWE) can provide deep insight into how a drug is actually used and how it performs in the real world with all its variety of settings and circumstances. This paper explores how RWE is transforming drug development, the new opportunities and benefits from RWE, and the challenges that remain.
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A collection of scholarly works about individual liberty and free markets. A project of Liberty Fund, Inc.
"Sur l'admission des femmes au droit au cité" Journal de la Société de 1789, 3 juillet 1790, no. V. https://oll.libertyfund.org/titles/1014,
|Available in the following formats:
|Facsimile PDF
|This is a facsimile or image-based PDF made from scans of the original book.
A facsimile of the first edition of this essay. Condorcet's essay is an early defence of the right of women to particpate in politcs. It was written during the first years of the French Revolution.
The text is in the public domain.
This material is put online to further the educational goals of Liberty Fund, Inc. Unless otherwise stated in the Copyright Information section above, this material may be used freely for educational and academic purposes. It may not be used in any way for profit.