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Study Makes Case for Gardasil HPV Vaccine in Young Men
A vaccine that is FDA approved to protect young women from HPV (human papillomavirus), which is the leading cause of cervical cancer, can HPV infection in boys as well.
Thursday, Feb. 3, 2011 - The controversial human papillomavirus (HPV) vaccine Gardasil prevented external genital lesions in boys and young men — mainly genital warts — associated with the four virus strains targeted by the vaccine, researchers reported.
In an industry-sponsored multinational randomized clinical study conducted among more than 4,000 boys and young men, the vaccine also prevented infection by the four HPV strains, according to Dr. Anna Giuliano, of the H. Lee Moffitt Cancer Center and Research Institute in Tampa, Fla., and colleagues.
Giuliano and colleagues reported the results in the Feb. 3 issue of the New England Journal of Medicine.
The vaccine has been approved to prevent cervical, vulvar, and vaginal cancer, as well as precancerous lesions caused by HPV types 6, 11, 16, and 18, in girls and women ages 9 through 26.
It's also approved to prevent genital warts caused by types 6 and 11 in both males and females.
In December, 2010, on the recommendation of an advisory panel, the FDA expanded the indication to include anal cancer and anal intraepithelial neoplasia (AIN) grades 1, 2, and 3 caused by the four HPV vaccine types.
Outside experts greeted the current report with a mixture of enthusiasm and caution.
In an accompanying Perspective article, Dr. Jane Kim, of Harvard School of Public Health, said the report is "cause to celebrate the extraordinary potential" of HPV vaccination to improve public health.
But Kim and others added that the expense of the vaccine — about $400 for the complete series of three shots — combined with concerns about the durability of its immune response gives it an uncertain future as a preventive measure in boys and men.
Giuliano and colleagues studied 4,065 healthy boys and men, ages 16 to 26, from 18 countries in a randomized, placebo-controlled, double-blind trial of the vaccine. The primary efficacy goal was to show that the vaccine reduced the incidence of external genital lesions related to HPV types 6, 11, 16, or 18.
The volunteers were analyzed on an intent-to-treat basis, all participants who got either vaccine or placebo, as well as per-protocol -- which included only those who got vaccine or placebo and were negative for 14 strains of HPV, including the four vaccine strains, at baseline. The analyses were meant to mimic the general population and boys before their first sexual encounter, respectively.
But a major shortcoming of the study was the limited follow-up, according to Dr. Diane Harper, of the University of Missouri Kansas City.
In an e-mail to ABC News/MedPage Today, Harper said "duration of efficacy is not addressed, which is always, always, always the most important question" for public health purposes.
While the researchers reported that levels of anti-HPV antibodies peaked seven months after the last shot, Harper noted they gave no information on how quickly those levels tailed off. In trials among girls and women, she said, some women lost immunity to vaccine strains within five years.
The bottom line, she said, is that the vaccine is effective in males against genital warts, a non-life-threatening condition that is one-tenth as common as abnormal Pap smears among women -- but has yet to be shown to be effective against more serious disease.
On the other hand, the study was well done, rigorous, and adds important information to the discussion of whether to strengthen the current permissive recommendation to vaccinate boys, commented Dr. William Schaffner, of Vanderbilt University School of Medicine in Nashville, Tenn.
However, the data by themselves are not enough to "move the needle" toward a recommendation for universal vaccination, Schaffner said in an e-mail to ABC News/MedPage Today.
Like most experts reached by ABC News/MedPage Today, he said the cost of the vaccine is high and must be outweighed by its benefits -- an analysis that still needs to be done. "The higher the cost of the vaccine, the more benefit has to be demonstrated," Schaffner said.
The study was supported by Merck, the National Center for Research Resources, and the NIH. Giuliano reported financial links with Merck, as did several other authors. Several authors also are employees of the company.
Kim did not report any conflicts.
This article was developed in collaboration with ABC News.


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David vs. Goliath is one of those rousing Bible tales that, over the course of several centuries, has become the template for so many stories found in fables, literature, and cinema. Thanks to the human proclivity for compassion and empathy, the idea of the scrappy little guy triumphing against all odds by taking on and defeating a big bad bully makes for heart-warming copy. (Cue Rocky theme music here ...)
Yet, the idea that big is bad and small is good isn't necessarily a truism. But another way, sometimes Goliath isn't really such a bad guy... and sometimes, David is, well, a bit of an opportunistic shyster.
Case in point: the ongoing saga in Alberta involving Calgary-based Minhas Craft Brewery. Minhas employs a PR strategy in which it fancies itself as a hometown David going up against a pair of ruthless, foreign-owned Goliaths in the form of Labatt and Molson.
As I reported last November, company co-owner Ravinder Minhas loves to play the victim card. And why not? By doing so, he received a tax subsidy under Alberta's deeply flawed small brewer tax program that amounted to $5.6 million in 2010. (The program was meant to usher in an environment that allows for local craft breweries to flourish; alas, the precise opposite has occurred.)
Indeed, while Ravinder Minhas likes to position his brewery as an all-Canadian little guy taking on the world, when one examines this brewery a little more closely, such is hardly the case.
For starters, as previously reported, all the Minhas brewing jobs are actually located in Monroe, Wisconsin. That wouldn't be so bad if not for the fact that Minhas has its beer taxed at a lower rate than the big breweries (which actually employ Canadians.) Translation: the Alberta government is essentially subsidizing U.S. brewing jobs with taxpayer money.
But a little recent investigative work has uncovered that Minhas also runs a company called Global Distillers SRL. Do a search of Global Distillers and it turns out that it is based in that great Canadian territory known as... Barbados.
In fact, it turns out that all of Minhas's trademarks are registered to a Barbados-based company (See here). So much for wrapping himself in the Canadian flag. Indeed, Ravinder Minhas is apparently funneling all his profits from the Alberta tax subsidy into an offshore tax-sheltered haven.
The bottom line? Minhas beer is brewed in the U.S., subsidized in Alberta, and sheltered from taxes in Barbados. Some local hero.
And it's a good thing Minhas doesn't have to slum it when he goes south. That's because he has a swank resort in the Barbados, too -- the lavishly-appointed Minhas Villa, where rooms go for US$299 to US$675 per night depending on the season. In fact, Minhas Villa is a delightful place for Canadians to seek refuge from winter and soak up the sun. And one can only wonder about how many Alberta government officials have relaxed on the beach revelling in epic bonfire side stories of Minhas' small business heroics against the "big multinationals."
But alas, Minhas' business plan -- i.e., its reliance on Alberta tax subsidies -- has hit a snag. Based on his overall beverage production (which includes beer, soft drinks and spirits), Minhas is very likely over the 400,000-hectolitre limit. If so, according to the regulations, Minhas no longer qualifies for Alberta small brewer subsidies.
Which means the savvy entrepreneur is now employing Plan B: Minhas is supposedly building a new brewery in Calgary that is supposed to be opening in March 2012.
Situated in an industrial space that is less than 5,000 sq. ft., this facility will output less than one per cent of the volume of his 300,000 sq. ft. Wisconsin brewery (which pumps out 351,000 hectoliters of beer, making Minhas the 14th largest brewer in the U.S.).
Announced in a letter widely distributed into the Alberta government in late November, there is no doubt that Mr. Minhas' postage-stamp sized brewery is being played for all its worth. What better way to lobby for continued and increased Alberta government subsidies than touting Alberta "jobs and investment" -- even if the value of both are outstripped by the rich annual subsidies to Minhas' U.S. operations by an order of magnitude.
There are two sides to every story, of course. Except that when it comes to the Minhas file, nobody's talking. Alberta Gaming and Liquor Commission CEO Gerry MacLennan declined to comment. And shockingly, Ravinder Minhas -- who is somewhat of a media darling as long as the questions are softballs -- abruptly terminated our phone conversation without answering a single query.
Even so, the ball is now in the AGLC's court. Namely, will it revamp the regulations and continue to subsidize a brewery that brews all its beer in the state of Wisconsin and is essentially a Barbadian, not a Calgarian company? Or will the AGLC actually show some respect for Albertan taxpayer dollars and turn off the taps?
Stay tuned.

subset: commoncrawl


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Feeling overwhelmed by social media and social networks? Does it occasionally seem that all this connectivity comes at the expense of your free time? Struggling to decide whether to follow back or friend up that guy you met at the local Chamber of Commerce event whom you don't really know, but might be a useful contact some day?
Maybe it's time to set some social media limits.
Unless you're a professional athlete, or just happen to be the guy from my high school whose entire life revolved around the french horn, you probably have a multitude of interests. Finding other people with similar interests and connecting with them is the whole point of social media. I'm not suggesting that you only friend/follow people you actually know in "the real world". That's just an electronic version of your current address book. What's the point?
But, to avoid driving yourself crazy with Facebook and Twitter and Linkedin and Ning and Myspace and Flickr and Slideshare and YouTube and whatever-else-you're-into-Tube invites and distractions, here's my recommendation for creating some order amidst chaos. (incidentally, "order amidst chaos" was the runner-up for the name of this company. Convince & Convert won based on concerns about people misspelling chaos).
1. List Your Passions
This may sound ridiculous, and it certainly is Amish-level old school, but it absolutely works. Grab a piece of paper and a pen and write down all the things in the world that you are interested in and about which you can contribute. The second part of that equation is key. I'm moderately interested in learning how to make balloon animals, but I have literally nothing of value to add to the balloon animal community. Remember, one of the 5 ways to be a social networking smash is to be helpful.
2. Get Selective
Look at your piece of paper. If there are ten or fewer areas of interest written there, you're all set. Move to step 3. If you have more than 10, narrow down to the 10 that are most vital to you. How do you narrow? Imagine yourself sending tweets at 2am about that subject. Does the thought of doing so make you frustrated, or excited? If it's the former, cross it off.
In the interest of transparency (or translucency, the term Beth Harte coined that I prefer), here are my 10 in no particular order: Flagstaff, Greater Phoenix, Food/Wine, Social Media, Email, PR, Fantasy Football, Jeep, Travel/Home Exchange, Indie Rock.
3. Assess Your Peeps
I find the best way to do this is with Facebook friends, but you may find better results using Twitter followers or some other collection of connections. Look through your current contacts and put a hash mark next to whichever of your 10 interests each friend shares. This doesn't have to be a massive spreadsheet or anything, but taking the time to look at your current contacts and examine WHY they are connected to you will help create social media limits.
4. Create Your Spheres
Take your piece of paper and pen and draw circles for each of your 10 interests. If the interests (or the communities around the those interests) intersect, create intersecting circles. The idea is to find 5 or 6 interests that you love, but that also are related enough so that you can introduce people from one community to people in another community.
This is the digital equivalent of having a dinner party, and inviting groups of friends that you love for different reasons, many of whom don't know one another. Making those introductions – those connections – is what being a good host and community member is all about. The best way to narrow your list of 10 interests to 5 or 6 is to better understand how you can tie your communities together.
Here's how my final spheres look:
Flagstaff and Phoenix interesect a lot because a lot of people I know spend time in both places (like me). I'm interested in food and wine in Phoenix, but more so in Flagstaff, because that's where I review restaurants.
Social media and PR are of course related communities, and because I used to work in those industries in Phoenix, those communities overlap a bit.
The outlier here is music. I'm a big indie rock guy and have been for 20+ years. But, I'm finding that I spend less time in that community than I used to, and examining my spheres, I can see why. There's little time efficiency or connectivity potential. If I had to cut out an interest to make more time for the rest, that would be the one I'd throw overboard.
5. Use Your Filter
Presto! By identifying your spheres, you've created natural social media boundaries. Now, use those boundaries as a filter for future connections. If somebody wants to connect with me and they are a member of one my six spheres, chances are I'll friend/follow them back. If they aren't a member of one of those six, I probably won't connect – although balloon animal professionals are always welcome.
What are your spheres? Will you list them in the comments?
(photo by laffy4k)


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- WiFi
- Car park
- Spa
- Pets admitted
- Rural
- Transfer service
- Sports
Choose your room
The family-run Hotel-Pension Bleckmann is only a few steps from the Ringstraße boulevard, Vienna University and the Votive Church. It provides free Wi-Fi and a breakfast buffet. The rooms have a private bathroom, satellite TV and a desk. All rooms facing the street have sound-proofed windows. Most rooms look onto the courtyard and are very quiet. For an additional fee, guests at the Bleckmann can park their cars in a parking garage across from the hotel. The closest tram and bus stops are only 325 ft away. The Schottentor Underground Station at the edge of the historic first district of Vienna is only a quarter mile away. The Museum Quarter and the Hofburg Palace are 3 subway stops away.
Reviews: Hotel Pension Bleckmann
Useful information:Other names for Hotel Pension Bleckmann:
Bleckmann Pension


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Niners CEO Jed York said All-Pro outside linebacker Aldon Smith would seek treatment, presumably for a substance-abuse problem, and would not be with the team when it visits the Rams on Thursday night in St. Louis.
York offered no timetable for Smith's return. Smith, 23, was arrested at 7:02 a.m. for suspicion of DUI after his pickup slammed into a tree in a residential neighborhood in San Jose. It was the latest off-the-field incident for Smith, who was also arrested for DUI in January 2012 and stabbed at a party at his house 15 months ago.
"I'll support our players as long as they're willing to work towards getting better, and being better teammates, and being better member of the community," York said. "And I believe Aldon wants to do that. And I will support him and I will stand by him as long as that's what he's willing to do … I believe Aldon wants to tackle this problem and we're going to do everything we can do to help him with this."
Smith addressed reporters after the 49ers' 27-7 loss to the Colts at Candlestick Park. He exhaled deeply before speaking, without notes, for about 30 seconds. Before Smith spoke, 49ers public relations director Bob Lange said he would not take questions.
"First off, I wanted to apologize to the team, the organization, my family, everybody I let down," Smith said. "I just wanted to let it be known that this is a problem and it's something I will get fixed. And I will do everything within my power to make sure this never happens again. I also wanted to let everybody know that, once again, I'm sorry. Like I said, this won't happen again."
York said he met with Jim Harbaugh and general manager Trent Baalke regarding Smith's playing status for Sunday. Smith didn't miss a defensive snap, collected five tackles and no sacks. York said Smith wanted to play, and he suggested the 49ers allowed him to do so because of his willingness to seek treatment. Smith earns about $99,000 in base salary per game.
"Our opinion was sitting somebody down, and paying them to sit down, when they are going to seek treatment in the future didn't seem like an appropriate punishment," York said. "I k now it might not sound reasonable, but for Aldon to be able to face the media, face his teammates and take full responsibility for what he's doing, we felt that was the best situation for Aldon himself. And for the team. And, ultimately, for the community at large. I realize people might not agree with that decision. That was the decision that we felt was best."
Without Smith, either Dan Skuta or rookie Corey Lemonier, a third-round pick, will start in his place Thursday night. Skuta, who was an inside linebacker during his first four seasons in Cincinnati, has made four starts since entering the NFL as an undrafted free agent in 2009. The 49ers traded two outside linebackers — Parys Haralson and Cam Johnson — before the season opener.
The 49ers could also be without All-Pro inside linebacker Patrick Willis, who left Sunday's game late in the third quarter with a groin injury. Willis declined an interview request after the game and the severity of his injury is not known.


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Aluminum Oxide White - 5 Lbs
- Item #: AOw5Lbs
White Fused Aluminum Oxide (Al2O3) (Alumina)
White Fused Aluminum Oxide is a high purity fused aluminum oxide. It achieves its white color as it is lower in impurities than brown or pink fused aluminum oxide. It typically has higher friability than brown fused aluminum oxide. With a Mohs hardness of 9, Aluminum Oxide is a high strength, wear-resistant material possessing a strong ability to resist vigorous chemical attacks (such as acid and alkali) at extreme temperatures. Its high degree of refractoriness, along with its superior electrical insulating properties, dielectric properties, and high melting point make White Fused Aluminum Oxide a desirable material choice for a diverse range of applications. Panadyne offers a full range of aluminas to meet your application. Our Aluminum Oxide is offered in standard FEPA grading or custom sizing. The white fused aluminum oxide is available in standard and microdermabrasion grade.
Aluminum oxide is lighter than metallic media and has twice as many particles per pound. Al2O3 is able to provide a fast cutting action which minimizes damage to thinner materials by eliminating surface stresses caused by heavier, slower-cutting media.
White Al2O3 is used in the Automotive & aircraft industries for things like cleaning engine heads, valves, pistons and turbine blades. It is also used for preparing hard surfaces for painting.
Typical Properties:
- High Hardness
- High Compression Strength
- Abrasive Wear-Resistance
- Ability to Resist Vigorous Chemical Attacks at Extreme Temperatures
- High Degree of Refractoriness
- Superior Electrical Insulating Properties
- Dielectric Properties
- High Melting Point
Typical Applications:
- Refractories
- Body and Vehicle Armor
- Blasting Media
- Microdermabrasion
- Grinding
- Polishing
- Lapping
- Metal Preparation
- Anti-Slip
- Laminates
- Coatings
- Filtration
- Abrasives
- Refractory
- Milling


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27 September, 2011 | (01 hr)
Sign In to access this Webcast
This Conference KeyNotes Webcast will provide highlights of the keynote address from The 2011 Corporate Citizenship and Sustainability Conference (June, 2011). James Weigand, President, DuPont Sustainable Solutions will discuss "Sustainability and Ethics: A Vibrant New Partnership."
Video footage of the conference will set context for live questions and answers with the presenter.
Who Should Attend:
Executives responsible for Corporate Citizenship, Corporate Responsibility, Sustainability
Dawn Rittenhouse
Ms. Rittenhouse is director of Sustainable Development for the DuPont Company. Ms. Rittenhouse joined DuPont in 1980 and has held positions in Technical Service, Sales, Marketing, and Product Management within the Packaging and Industrial Polymers business and Crop Protection businesses. In late ...Full Bio
James R. Weigand
Mr. Weigand leads a global consulting, training and technology licensing business specializing in workplace safety, process safety management and environmental management. The vision of DSS is to lead the transformation of workplaces and work cultures to become safer, more efficient and env...Full Bio


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SA Orthopaedic Journal
versión On-line ISSN 2309-8309
versión impresa ISSN 1681-150X
SA orthop. j. vol.13 no.1 Centurion ene./mar. 2014
Giant cell tumour of the tendon sheath (GCT-TS) in the foot: A case report
Z Mayet
BSc, MBChB, FC Orth(SA), MMed Orth(Wits) M Street MBBCh, Registrar T Noble MBBCh, Intern, Chris Hani Baragwanath Academic Hospital SKM Magobotha FC Orth(SA), Deputy Head of Department (CHBAH). Division of Orthopaedics, University of the Witwatersrand, Johannesburg
Giant cell tumour of the tendon sheath (GCT-TS) has been described as the most common tumour of the hand following ganglion cysts. In contrast it is much rarer in the foot, with only 3-10% of GCT-TS being described in the foot. A PubMed and Medline search of the topic has revealed two case series and 12 case studies. It is therefore an uncommon condition, but should be considered as part of a differential diagnosis for a mass in the foot.
We present the case of a 42-year-old male who presented with a large painful mass in in the third web space of his left foot, which was 7 cm in length in vivo. It crossed the anatomical compartments of the forefoot and midfoot. Our case report showed the typical findings of a GCT-TS. Along with this we also present a review of the literature.
Key words: giant cell tumour of the tendon sheath, GCT-TS, benign tumours, foot tumours.
Giant cell tumour of the tendon sheath (GCT-TS) is a benign, solitary, proliferative tumour that arises from the complex of the tendon sheath of small joints in the hands and feet.1 GCT-TS occurs most commonly in the fourth to fifth decades, but can occur between 10 and 60 years.2 The female to male ratio is 3:2 and there is no racial prepon-derance.2,3 GCT-TS has been described as the most common tumour of the hand after ganglion cysts.2,4 In contrast it is much rarer in the foot, with only 3-10% of GCT-TS being described in the foot,2 and is reported to make up 0.8% of foot and ankle masses.5 This equates to a condition that is not rare, but is uncommon.
The case presented here shows the typical findings of GCT-TS, which grew to a considerable size due to its long history. It crossed the anatomically confined spaces of the forefoot and midfoot. We further present a review of the topic.
Case report
A 42-year-old male presented with a painful mass in the third web space of his left foot. It was a slow-growing mass, which was first noticed many years earlier.
Approximately 12 years prior to presentation, a biopsy was performed from the dorsal aspect of the foot at a peripheral hospital. No clinical notes or histology results were available to us. At the time of presentation to our unit, the patient complained that the mass had increased in size considerably over the last year, and he felt as if he was walking on a stone. Despite the use of orthotics and shoe-wear modifications, he was experiencing a lot of pain on weight bearing and he complained of numbness in the third and fourth toes.
Examination of the foot revealed a healed surgical incision in the third web space. There was a fullness visible in the area on the dorsum and plantar aspects, and the third and fourth toes were splayed. Palpation revealed a large mass that was more prominent on the plantar aspect of the foot (Figure 1), and its full extent could not be felt. The mass was non-tender, but there was pain when the metatarsals were compressed to perform a Mulder's test. Sensation was altered in the third web space and on the third and fourth toes. He had an antalgic gait and he preferred heel walking because of the pain. His general examination was unremarkable and he was in good health. There were no lymph nodes palpable.
His X-rays showed a soft tissue mass in the third inter-metatarsal space, with splaying of the adjacent rays. There were no bony erosions, and no calcifications in the mass. Serology was unremarkable. Our differential diagnosis at this point was giant cell tumour of the tendon sheath, synovial sarcoma and Morton's neuroma. We also considered tuberculosis and pigmented villonodular synovitis, but these were thought to be less likely.
An MRI scan of the lesion revealed a well circumscribed mass in the third intermetatarsal space, which extended into the plantar aspect. It was homogenous and showed a low intensity on the T1 and T2 images. It enhanced on the gadolinium images of the MRI. The proximal aspect of the mass could not be well visualised on the available films or on the computer, but was thought to be around the level of the tarsometatarsal joints. The size measured on MRI was 33 mm x 26 mm x 27 mm (Figures 2 and 3).
The mass was excised in its entirety. This was achieved through a primary dorsal incision which spanned the intermetatarsal space (Figure 4). The distal end was blind-ending, and no flexor tendons were seen distally to the third and fourth toes. Proximally a second incision was needed on the plantar aspect. The mass was found to originate from the tendon, and a tenotomy was performed proximal to the mass through healthy tendon. A large, yellowish-tan, rubbery-hard mass was removed. It measured 7 cm in length in vivo, which was larger than that seen on MRI (Figure 5). Its length in situ appeared to be much longer, which is probably due to the elasticity of the tendon and mass. The wound was found to have no residual traces of the mass. Digital nerves were not seen in the intermetatarsal space. Closure was done on a Portavac drain, and compression dressings were applied in an attempt to close down the splaying of the rays.
Macroscopic examination of the specimen showed a lobulated mass with no areas of calcification, haemorrhage or necrosis. It had a yellowish-tan colour. Microscopic examination showed a spindle cell neoplasm arranged in fascicles. Interspersed between the spindle cells were osteoclast-like giant cells (Figure 6). There was a background chronic inflammation, and haemosiderin pigment was seen. Two mitoses were seen per 10 HPF. The periphery of the specimen was covered in adipose tissue and skeletal muscle. A final diagnosis of GCT-TS was made.
The post-operative period was uneventful and the patient did very well. He has no problems with weight bearing or footwear and the splaying has disappeared. He reports normal sensation and no pain. There are no signs of recurrence after 1 year of follow-up.
A PubMed and Medline search of the topic for articles in the English language has revealed two case series, and 12 case studies. The first series of 17 patients was collected retrospectively over 17 years.1 The second was also a retrospective study of 20 patients treated over 5 years.6 This is in keeping with GCT-TS being an uncommon condition.
The most common site of occurrence was originally described as the great toe.2 Wang et al however presented a group of 30 patients presenting for ultrasound of GCT-TS, of which seven (23.3%) were foot cases. Most of these occurred in the forefoot.4 A review of the articles in the orthopaedic literature gave us 49 cases to evaluate the anatomic site of origin1,3,4,7,8-15(Figure 7). The forefoot had 32 cases (65%)- of which 81% occurred on the medial side. The midfoot had four cases (8%) and the hindfoot 11 cases (22%). There were a further two cases that crossed anatomical boundaries. The first is our case which involved the flexor digitorum longus tendon and crossed the forefoot and midfoot with a 12-year history. The second case involved a longstanding large tumour reported in the extensor digitorum longus tendon which crossed anatomical boundaries of the hindfoot- midfoot and forefoot.9
Figure 7 also shows a case of a tumour in the fourth toe. This was a case report of a large tumour in the form of a macrodactyly after an 11-year history.11
Table I presents a comprehensive differential diagnosis for foot and ankle masses and GCT-TS. As is usual with such long lists, most conditions will be excluded by clinical presentation, including site of the lesion.516 The few remaining conditions are usually difficult to exclude, even after radiology, and a diagnosis has to be made histologically. Pre-operative diagnostic accuracy in the two case series was 20% and 17.6%, which highlights the difficulty clinicians have with making a diagnosis.1,4
Patients will generally present with a painless mass that gives discomfort on weight-bearing or difficulty with footwear.1 Occasionally there is an associated sensory deficit secondary to compression of the digital nerves. There are also two reports of patients with GCT-TS presenting with hallux valgus deformities.8,12 Plain radiology may show a soft tissue mass or swelling which may cause splaying and erosion of the adjacent bone.3 However to make a diagnosis using radiology, an ultrasound or MRI is needed.
GCT-TS is seen as a hypo-echoic nodule with ultrasonog-raphy. The mass could have either homogenous or heterogenous echogenicity. Under Doppler imaging, 71% of lesions also show substantial flow, while the rest show minimal flow. A finding of hypervascularity is typical of GCT-TS; however, it is not specific. This hypervascularity has led to a misdiagnosis of haemangioma.1 It will however exclude ganglions, which are typically avascular or anechoic.4,17
MRI is considered an important diagnostic tool, and has very typical features. GCT-TS has a low intensity signal on T1 and T2 weighted images, and has homogenous enhancement on gadolinium-enhanced images.6,18 These findings, although typical, are not absolute or specific. Most lesions are said to be hypointense as compared to muscle; however, some are isointense. These low signal images also occur in pigmented villonodular synovitis, densely mineralised tumours and tumours with large amounts of fibrous tissue. A gradient-echo sequence is helpful to be able to differentiate haemosiderin from fibrous tissue.6,17,18
A definitive diagnosis however can only be made on tissue samples. This is routinely done by histology. Stromal cells can either be spindle-shaped or polygonal. The nuclei of stromal cells are a source of much debate in microbiology, but are now said to be of variable morphology. Giant cells which resemble osteoclasts are also seen. Mitoses vary considerably from 0-9 per 10 HPF. Lastly, xanthomatous change is present and haemosiderin-laden macrophages can be seen. Fine-needle aspiration can also be considered, with Venkateswaran et al stating that cytodiagnosis is now possible. Cytology findings generally mirror the features on histology as he found in a 20-case series.19
Treatment takes the form of a marginal excision. Recurrence rates are quoted as 0% at 85 months and 20% at 5 years in the two available case series.1,6 None of the case studies reported any recurrences, and complete local excision is stated as the only method of preventing recur-rence.1,3,4,7-9,20 Recurrence is treated by marginal excision in the case of the localised forms that occur in GCT-TS of the foot. Radiotherapy is used as an adjunct in other forms of the disease outside the hand and foot.20 There was no mention of any malignant transformation in any of the literature for masses appearing in the foot and ankle.
GCT-TS is an uncommon condition in the foot and ankle, with most orthopaedic surgeons seeing only one case in a career. It presents as a mass in the foot and ankle, and making a definitive diagnosis is difficult without histology. Clinical features are usually of a slow-growing mass that causes compressive symptoms. Findings on MRI are typically of low signal intensity on T1 and T2 images. Our case report showed the typical features. However, because of the longstanding nature of the case, our patient presented with an unusually large mass, which crossed the confined anatomical spaces of the forefoot and midfoot.
1. Gibbons CLMH- Khwaja HA-Cole AS-Cooke PH- Athanasou NA. Giant-cell tumour of the tendon sheath in the foot and ankle. JBJS-B 2002;84-B(7):1000-1003. [ Links ]
2. Giant cell tumor of tendon sheath - foot and ankle http://www.bonetumor.org/tumors-foot-and-ankle/giant-cell-tumor-foot-and-ankle [ Links ]
3. Occhipinti E- Heinrich SD- Craver R. Giant cell tumor of tendon sheath arising in the toe. Fetal and Pediatric Pathology 2004;23:171-79. [ Links ]
4. Zhang Y- Huang J- Ma X- Wang X- Zhang C- Chen L. Giant cell tumor of the tendon sheath in the foot and ankle: case series and review of the literature. J Foot Ankle Surg 2013;52(1):24-27. [ Links ]
5. MacDonald DJM- Holt G- Vass K- Marsh A- Kumar CS. The differential diagnosis of foot lumps : 101 cases treated surgically in north Glasgow over 4 years. Ann R Coll Surg Engl 2007;89:272-75. [ Links ]
6. Yuexiang Wang-Jie Tan- Yukun Luo. The value of sonography in diagnosing giant cell tumors of the tendon sheath. J Ultrasound Med 2007 26:1333-40. [ Links ]
7. Findling J- Lascola NK- Groner TW. Giant cell tumor of the flexor halluces longus tendon sheath. J Am Podiatr Med Assoc 2011;101(2):187-89. [ Links ]
8. Kuo CL- Yang SW- Chou YJ- Wong CY. Giant cell tumor of the EDL tendon sheath : An unusual cause of hallux valgus. Foot Ankle Int 2008;29(5):534-37. [ Links ]
9. Guryel E- Coleridge S- Bendall S. Unusual presentation of a giant cell tumor of the tendon sheath in a foot. J Surg Orthop Adv 2004 13(2):110-11. [ Links ]
10. Muramatsu K- Mine T- Ichihara K. Atypical tenosynovial giant cell tumor of the extensor hallucis longus tendon. J Am Podiatr Med Assoc. 2006 Jul-Aug;96(4):359-61. [ Links ]
11. Skaliczki G- Mady F. Giant cell tumor of the tendon sheath of the toe imitating macrodactyly: case report. Foot Ankle Int. 2003 Nov;24(11):868-70. [ Links ]
12. Young KW- Lee KT- Kwak JJ- Lee YK- Park YU. Mass-induced unilateral hallux valgus. Orthopedics. 2010 Dec 1;33(12):927. [ Links ]
13. Vasconez HC- Nisanci M- Lee EY. Giant cell tumour of the flexor tendon sheathof the foot. JPRAS 2008;61:815-18. [ Links ]
14. Ming Xie BM- Kai Xiao MM- Zhen-hua Fang MM- Jing-jing Zhao MM- Wu-sheng Kan BM. Giant cell tumor of the tendon sheath of the toe. Orthopaedic Surgery 2011;3(3):211-15. [ Links ]
15. Goni V- Gopinathan NR- Radotra BD- Viswanathan VK-Logithasan RK. Giant cell tumour of peroneus brevis tendon sheath a case report and review of the literature. BMJ Case Rep 2012;13. [ Links ]
16. Bos GD- Esther RJ- Woll TS. Foot tumors : Diagnosis and treatment. JAAOS 2002;10(4):259-70. [ Links ]
17. Ganguly A- Aniq H- Skiadis B. Lumps and bumps around the foot and ankle: an assessment of frequency with ultrasound and MRI. Skeletal Radiol 2013;42:1051-60. [ Links ]
18. Llauger J- Palmer J- Monill JM- Franquet T- Bague S- Roson N. MR imaging of benign soft tissue masses of the foot and ankle. Radiographics 1998 Nov-Dec;14(6):1481-98. [ Links ]
19. Venkateswaran K- Kusum K-Kusum V. Fine-needle aspiration cytology of giant cell tumor of tendon sheath. Diagnostic cytopathology 2003;29(2):105-10. [ Links ]
20. Van Der Heiden L- Max CL. Gibbons H- Bass Hassan A- Kroep JR- Gelderblom H- Van Rijswijk CSP- Nout RA- Bradley KM-Athanasou NA- Sander Dijkstra PD- Hogendoorn PCW- Van De Sande MAJ. A multidisciplinary approach to giant cell tumors of tendon sheath and synovium - a critical appraisal of literature and treatment proposal. Journal of Surgical Oncology 2013;107:433-45. [ Links ]
Dr Z Mayet
Division of Orthopaedics
PO Bertsham 2013
Tel: (011) 933-8914
Email: email@example.com
The content of this article is the sole work of the authors, and no benefit of any form has been received or will be received from any commercial party.


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San Francisco will probably always struggle to shrug off the 40-year-old 'Summer of Love' weight of history that hangs over one the most beautiful and chilled of US cities. We've had punk, Bay Area thrash metal and hardcore since, but the love and peace era personified by the Haight-Ashbury hippie revolution and the Golden Gate Park 'Be-Ins' of 1967 continue to fascinate.
Recently a handful of bands loosely based in and around the city have taken the free experimental spirit of '60s bands such as the United States of America, the Velvet Underground, Silver Apples, and the West Coast Pop Art Experimental Band and filtered their sound through the motorik shuffle of krautrock and the discordance of obscure minimalist composers. I spoke to Wooden Shjips guitarist/vocalist and founder member Ripley Johnson via the magic of e-mail and asked him to explain a few things about their retro-futurist sound.
When I listened to the recent Wooden Shjips track on last month's Mojo cover-mounted CD I got the track listing mixed up and initially thought I was listening to the early Soft Machine demos when in fact it was your track! Anyway, it piqued my interest being one of only two contemporary tracks on the CD. Is it possible to explain how the band came to be and how its original improvisational style mutated into the band's sound today?
"Ha ha! I don't really know much about Soft Machine either, though I've read good things. The original plan was to integrate elements of different genres of music: the minimalist movement of the '60s and '70s, especially the music of Angus MacLise, Terry Riley and John Cale; primitive rock, a la the Velvet Underground, Link Wray, the Seeds; and the improvisation of jazz and psychedelic rock. Originally we just jammed together and felt our way forward. No real songs. We did that for about nine months before playing our first show."
From an admittedly unseasonably warm autumnal London it's easy to romanticise a San Francisco/West Coast scene in which you're swapping riffs with Howling Rain, Earthless and Assembled Head in Sunburst Sound. Is there any reality to this at all?
"Ha! Unfortunately, no. We opened a Roky Erickson show with Howlin' Rain earlier in the year, and we have a show with Earthless coming up. That's about the extent of it so far."
Whilst referencing some classic '60s and '70s psych/kraut and experimental bands, your music (to me anyway) seems equally informed by a more '80s aesthetic of taking these influences and spinning them (I'm thinking Loop, Spacemen 3, Scientists etc here). Does my shoddy theory have any relevance? I'm not saying you're stuck in the '80s!
"Actually, no. We've gotten those comparisons before. Obviously, we need to go record shopping. I really like Loop, but it's a relatively new discovery. I don't think the other guys have heard any of those bands. I suspect that they were influenced by the same music as us: Velvet Underground, Stooges, 13th Floor Elevators, etc. I think it's just natural for bands to want to beat a riff into the ground over and over. It's always been that way. Whether krautrock, or the electric Miles Davis bands, or ? and the Mysterians."
In this age of blogs and MySpace sites I was, after hearing your track on the Mojo cover mount, able to track down a lot of info about you very quickly. Do you think this loss of any intended or accidental mystique is a good or bad thing?
"It's just different. I grew up deciphering album covers for little clues about a band, and referencing the Harmony Encyclopaedia of Rock for discographies. Hunting for records used to be more of a sport. If someone really wanted to remain a mystery today, I think they could. It would take a profound commitment. The flipside is that you can be relatively obscure and have a substantial audience. That's good for everyone."
You've released some hard to find, over here anyway, singles: is the plan to keep releasing odd singles with various labels?
"Absolutely. How we'll release them, I don't know. In some ways it's easier to do it ourselves because we can keep the overhead low and the turnaround quick. We just co-released one with Holy Mountain to benefit Food Not Bombs. The first pressing proceeds will go to them, the second pressing will go towards our rent. We like that model and are thinking of doing a holiday record in a similar way."
Could you describe the Wooden Shjips live experience and are there any plans to bring the Wooden Shjips over to Europe/UK to play in the foreseeable future?
"From my perspective on stage, I would describe it as loud and loose. We would love to come to the UK. We're hoping sometime next year!"
Let's hope they do! Wooden Shjips' debut album is released on the mighty Holy Mountain label and is in the shops now; the DiS review can be found here. Feed your head at MySpace.


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A red tide bloom moved northward to Siesta Public Beach, causing respiratory problems for beachgoers and tourists vital to the region's economy.
UPDATE: Countless dead fish washed ashore Thursday morning on Southwest Florida shorelines, including Siesta Public Beach, as a red tide bloom moved northward, causing respiratory problems for beachgoers and an eyesore for tourists vital to the region's economy.
The greatest concentrations of red tide were reported along Siesta Key, from Turtle Beach at Midnight Pass Road south to Blind Pass Beach. Fish kills and respiratory difficulties have also been reported on Holmes Beach and as far north as the tip of Anna Maria Island.
The bloom and its toxins are expected to linger offshore for about a day and then return south as winds shift, blowing from the north, said Jason Lenes, a researcher with the Center for Prediction of Red Tide at the University of South Florida.
"The bloom has the potential to leave the area but could linger," Lenes said, adding that the bloom could be sustained if algae near the ocean bottom rise to replace departing algae near the surface.
By Saturday or Sunday, the bloom is expected to move southward along the shores in south Sarasota and Charlotte counties, Lenes added, and then possibly move west into the Gulf.
Windy weather is forecast to continue today, creating high surf conditions on the beach. Forecasters expect breezy conditions to continue through Saturday, with gusts exceeding 20 mph.
Florida red tide blooms are caused by single-cell algae called Karenia brevis. The algae occur naturally at very low levels, usually about 30 miles offshore. Typically during the fall, ocean currents move the red tide to the coast. If conditions are right, the cells proliferate into a toxic bloom.
The last major bloom here ended in January 2007, after nearly six months. Prior to that an enormous bloom that began in January 2005 lingered for 13 months before dying off in February 2006.
Virginia Haley, president of Visit Sarasota, said noxious air and fish-littered beaches are problematic for the region's tourism-based economy, but not devastating because many visitors book extended trips ahead of time.
"When it's happened in the past you didn't really see a huge impact in the tourist season," Haley said, "except a huge drop in our overall visitor satisfaction."
Sarasota typically ranks in the 90s in visitor surveys, Haley said, with two memorable exceptions: a long cold snap in 2010 and the last red tide outbreak.
The greatest hurdle for tourism officials is getting up-to-date information to visitors as conditions quickly change.
"I'll get a call from a bride, and she'll say should I continue my plans for a beach wedding?" Haley said, exasperated. "It's the uncertainty that makes it difficult."
Murky water and pungent air greeted those who visited Siesta Beach Thursday, as snowbirds and residents slowly walked the shores inspecting piles of small dead fish.
Some beachgoers experience coughing, sneezing, scratchy throat or teary eyes, effects that are temporary and typically subside away from the beach.
Many were coughing and said they had even more trouble breathing earlier in the morning, before winds shifted from a direct hit on the shore.
"It was so strange," said Deloris Pollard, visiting from Dayton, Ohio. "You would see one person cough and then another."
"Like a chain reaction," her husband, Jim Pollard, interjected.
About a mile north, near Siesta Village, 75-year-old Marcy Shelling weaved through the fish during a morning walk.
"It's terrible," the Michigan resident said.
She's visiting for nine weeks, and though the fish kill and toxins in the air have hampered her beach experience, she says she's sticking around.
"You do what you can do," Shelling said. "And you accept it."
In Venice on Wednesday, beach walkers found signs of red tide along Caspersen Beach. While there was only a faint whiff of the noxious air, dead fish lined the shore north of the Venice Fishing Pier.
Sarasota County workers, along with nonviolent offenders enrolled in Sarasota County sheriff's offender work program, removed dead fish that washed on Caspersen Beach.
Other cleanup efforts were under way at other county beaches, including Manasota, Blind Pass and Venice.
EARLIER: Higher levels of the algae that causes red tide have been found at several Sarasota County beaches, including Siesta, Nokomis and Venice, as a red tide patch from Charlotte Harbor moves northward where its effects could harm beaches and shoo away tourists vital to the regional economy.
The greatest concentrations of red tide were reported along Siesta Key, from Turtle Beach at Midnight Pass Road south to Blind Pass Beach.
Sarasota County lifeguards reported slight to moderate respiratory irritation caused by red tide's airborne toxins blowing ashore at various beaches, according to a Sarasota County news release. Dead fish have also washed ashore in some places.
Beachgoers may experience coughing, sneezing, scratchy throat or teary eyes. The effects are temporary and should subside once away from the beach.
But people with asthma or other chronic respiratory conditions are warned to avoid areas where red tide has been reported because toxins can trigger their conditions.
County officials said they hoped that a cold front predicted for Thursday will change wind patterns and reduce the effects of red tide over the weekend.
South-southwesterly winds are expected to shift Thursday, blowing more from the north over the next several days.
In Venice, beach walkers found signs of red tide along Caspersen Beach Wednesday morning. While there was only a faint whiff of the noxious air that can cause watery eyes and coughing, dead fish lined the shore, north of the Venice Fishing Pier.
Residents and tourists were also startled by an apparently unrelated fish kill to the north where hundreds of dead fish washed ashore from North Manatee Beach to the tip of Anna Maria Island Tuesday and Wednesday.
All the fish found and collected by Manatee County Parks and Recreation crews were male mullet, suggesting the dead fish had been unloaded by Gulf fishing crews harvesting female mullet for their roe.
"If it was red tide you would have all types of species dead," said parks worker Lee Copeland as he shoveled a pile of dead fish into a plastic bag.


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She is the daughter of the late Walther Sommerlath and his Brazilian wife Alice, née de Toledo, also deceased. The Queen has two older brothers: Ralf and Walther Sommerlath. Her third brother, Jörg Sommerlath, passed away in 2006.
The Sommerlath family lived in Sao Paulo, Brazil between 1947 and 1957, where Walther Sommerlath held various positions, including President of the Brazilian subsidiary of Swedish company Uddeholm. The family returned to West Germany in 1957.
After graduating, Silvia Sommerlath worked at the Argentinean Consulate in Munich.
The engagement of King Carl XVI Gustaf and Silvia Renate Sommerlath was announced on 12 March 1976. They were married on 19 June the same year, at Stockholm Cathedral.
Initially the Royal Family lived in an apartment at the Royal Palace of Stockholm. In 1982 they moved to Drottningholm Palace.
She makes regular visits to national and municipal authorities, as well as schools, universities and other educational institutions, in order to gather information.
She frequently participates in anniversary events, openings of conferences and symposia and other official events.
The Queen is a member of the Lutheran Church of Sweden.


text:
Buy A Boat
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2004 Princess 45 Flybridge The 45 is, above all, a boat for enjoying convivial company. - 46'
Euros €269,000
Lignano, Italy
Hull Material
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4.27 m
Length on Deck:
13.64 m
Draft Drive Up:
Direct Drive
Dry Weight:
12501 kgs
Volvo Penta
Engine Model:
Engine(s) HP:
(1662 Liters)
(588 Liters)
Hull Shape:
Modified Vee
Additional Specs, Equipment and Information:
Designer: Olesinski
Flag of Registry: Austria
Hull Shape: Modified Vee
LOA: 13.92 m
Beam: 4.27 m
Length on Deck: 13.64 m
Minimum Draft: 1.30 m
Dry Weight: 12501 kgs
Total Power: 960 HP
Engine 1:
Engine Brand: Volvo Penta
Year Built: 2004
Engine Model: TAMD 75P EDC
Engine Type: Inboard
Engine/Fuel Type: Diesel
Engine Hours: 495
Drive Type: Direct Drive
Engine Power: 480 HP
Engine 2:
Engine Brand: Volvo Penta
Year Built: 2004
Engine Model: TAMD 75P EDC
Engine Type: Inboard
Engine/Fuel Type: Diesel
Engine Hours: 495
Drive Type: Direct Drive
Engine Power: 480 HP
Fresh Water Tanks: (588 Liters)
Fuel Tanks: (1662 Liters)
Number of single berths: 6
Number of heads: 2
Seating Capacity: 10
TV set
Inside Equipment
Microwave oven
Manual bilge pump
Air conditioning
Hot water
Electric head
Battery charger
Sea water pump
Electric bilge pump
Bow thruster
Electrical Equipment
Shore power inlet
Electrical Circuit: 220V
Outside Equipment/Extras
Hydraulic gangway
Cockpit table
Cockpit cushions
Cockpit shower
Swimming ladder
Teak cockpit
Electric windlass
Cockpit cover
Bimini Top
The 45 is, above all, a boat for enjoying convivial company and the excitement of cruising. The flybridge is an entertaining area in its own right, and there is stowage on the extended swimming platform for a tender or wetbike. Accommodating three cabins in a craft this size without sacrificing comfort is a remarkable achievement. Doing so in a boat with exhilarating performance, self-assured seakeeping and long-range cruising abilities is exceptional.
Additional Description
INTERIOR FINISH * Furniture finished in natural cherry wood with clear lacquer finish, (classic cherry optionally available) * Console area finished with burr elm panels * Galley worktop in Avonite (or similar) * Choice of upholstery fabrics, carpets and curtains from co-ordinated range * Timber laid galley floor. STORAGE * All suites and cabins have generous storage comprising lockers, drawers and shelves as appropriate.
Additional Description
AFT COCKPIT * Self-draining * Teak laid deck * Upholstered L-shaped seat with fender and life raft stowage space below * Lockable gas strut assisted hatch to lazarette stowage area * Lockable access hatch to engine room * Steps to side decks and flybridge with teak capping * Overboard vented, self-draining locker for 2 Camping or Calor gas bottles * 220/240v shore support inlet and cable stowage locker * Cockpit lighting * Transom door leading to integral bathing platform * Cockpit cover * Stainless steel handrails * Reserve manual bilge pump * Remote fuel cocks located in locker * Full size transom bathing platform with teak decking, storage compartment, fixing points for dinghy or wetbike, foldaway swimming ladder, hot and cold shower. FLYBRIDGE * Helm position with repeat engine controls and instrumentation * Repeat log/echo sounder and autopilot controls * Hydraulic steering * Rudder position indicator * Trim tab controls * Anchor winch remote control * High speed compass * Searchlight remote control * Horn * Remote VHF handset location * Intercom to lower helm * Compass and instrument light controls * Visual and audible engine warning system * Bilge pump audible alarm * 2-seater helm seat * U-shaped upholstered sofa with drinks table * Double sunbed * Loudspeakers linked to saloon hi-fi * Integral stairway from aft cockpit with access hatch * Wind deflector screens * Stainless steel handrails * GRP radar arch * Console and seat covers * Matched whip aerials for VHF R/T and radio.
Additional Description
DECK SALOON * U-shaped sofa with dining table to starboard * Moveable 2 seater sofa opposite * Stereo CD/radio with saloon and exterior speakers * Sideboard with refrigerator (24v/240v), glass, bottle and general stowage * Tinted opening side windows * All windows in toughened safety glass with stainless steel frames * Triple stainless steel framed sliding doors to cockpit, for maximum opening * Curtains, venetian blinds or sunscreens to all windows and doors * Overhead downlighters * Clock and barometer.OWNER'S SUITE * Large double bed with quilted bedspread * Dressing table with mirror * Large wardrobe * Cupboard with shelves * Storage locker * Forward mirror * Individual berth lights * Deck hatch with flyscreen and blindSTARBOARD GUEST CABIN * 2 full-size single berths with quilted bedspreads * Wardrobe with shelf space * Eye level and bedhead storage lockers * Downlighters and individual berth lights * 2 opening portholes.PORT GUEST CABIN * 2 full-size single berths with quilted bedspreads * Wardrobe * Storage locker * Downlighters and individual berth lights * 2 opening portholes * Mirror.
Additional Description
ELECTRICAL SYSTEMS 24 Volt: 2 x heavy duty batteries for engine starting * 4 x heavy duty auxiliary batteries * Engine alternators change via blocking diodes to isolate engine start batteries from auxiliaries * 45-amp 24v float battery charger connected to both battery banks * Remote battery master switches with control switch at main switch panel * Circuit breakers on all circuits. 220/240 Volt: Shore support inlet in cockpit locker with storage for cable * Polarity check system * Earth leakage safety trip * Circuit breakers on all circuits * Power points in owner's stateroom, guest suite, galley (double) and saloon (2) * Shaver points in both bathrooms.
Additional Description
GALLEY * Avonite (or similar) worktop * Recessed 3-burner gas hob with flame failure protection and cover * Combination microwave/conventional oven with grill * Twin bowl stainless steel sink with mixer tap * Chopping board * 24v/240v fridge/freezer * Waste disposal bin * Hob extractor fan * Overhead lighting * Dedicated crockery and cutlery stowage * General storage cupboards * Water gauge * Opening porthole.
Additional Description
FUEL SYSTEM * Twin fuel tanks (in N4 marine grade alloy) with interconnection system giving 360 gallons (1636 litres) capacity * Fuel fillers on port and starboard side decks * High capacity fuel filters/water traps * Remote fuel cocks in cockpit locker * Fuel gauges at main helm. WATER SYSTEM * Water tank of 122 gallons (554 litres) plus 7 gallons (32 litres) hot water calorifier * Water heated by engine and 240v immersion heater * Automatic water pump with filter * Main circuit breaker at switch panel * Water level gauge * Deck filler. FIRE EXTINGUISHERS * Automatic fire extinguisher in engine room * Hand operated fire extinguishers (3) in owner's suite, guest suite and galley. BILGE PUMPS * Automatic electric bilge pumps (with manual override) in engine room, forward accommodation and aft lazarette (3 in all) * High capacity manual bilge pump with valve system and suction points in same areas.
Additional Description
POWER AND DRIVE SYSTEMS * Engine room soundproofed * High volume air intakes * Engine room extractor fan with electronic time delay * Engine exhaust silencers and water cooled exhausts * Engine beds integrally moulded with hull for strength and vibration absorption * Engines flexibly mounted * Engine room forward and aft bulkheads integrally bonded * Automatic fire extinguisher * Automatic and manual bilge pumps * Engine room lighting * Engine room access hatch and ladder from cockpit * Propeller shafts in Temet * 4-bladed Aquafoil propellers in nickel aluminium bronze * High speed, balanced rudders * Cathodic protection for sterngear * Sterngear, engines, fuel tanks, fillers etc all electrically bonded * Hydraulic steering system.
Additional Description
* Modified deep 'V' with moulded spray rails and incorporating propeller tunnels for improved propulsive efficiency and reduced draft * Hand laid glass fibre construction with isophthalic gelcoat backed by initial lay-up of powder bound matt and isophthalic resin * Integrally bonded girder stiffening system * Standard finish white high gloss gelcoat * GRP/balsa core/PVC foam sandwich construction for deck and superstructure, for strength and high thermal insulation * Moulded non slip surfaces on side decks, flybridge and cockpit decks * Integrally moulded flybridge stairway * Hull antifouled.
Additional Description
* Reversible electric anchor winch (1000W) with foredeck, main helm and flybridge controls * Self-stowing 16kg Delta anchor with 30 metres of chain * Stemhead roller with automatic anchor launch and retrieve * Deck hatch access to chain locker * Stainless steel bow, stern and spring cleats * Bow and stern fairleads * Stern rope storage lockers * Stainless steel pulpit and guard rails * Stainless steel coachroof and flybridge handrails * Foredeck hatch * Stainless steel rubbing band with rubber insert * Full set of IMCO navigation lights * Riding light * Searchlight with dual station remote controls * Twin electric horns * Intercom/loud hailer * Fuel and water fillers.
Standard Equipment
Dual station autopilot. Remote control electric anchor winch. Electro-hydraulic trim tabs. Dual station log and echo sounder with alarm. Flybridge sunbed. VHF R/T with dual station facilities. Flybridge intercom. Searchlight with remote control. Saloon/flybridge stereo CD/radio. Cocktail bar with refrigerator. Flybridge refrigerated coolbox. Triple opening stainless steel saloon doors. Stainless steel framed saloon windows and curved windscreen all in toughened glass. Transom door leading to full size bathing platform. Teak laid cockpit deck and transom platform. Hot and cold transom shower. 24v DC Electrical system 240v shore power with 45-amp float battery charger. Microwave/conventional oven/grill. Cockpit night cover.
Engine Options - Diesel
2 x Volvo Penta TAMD63P (2 x 370hp) Speed range: 26-28 knots 2 x Volvo Penta TAMD74L (2 x 430hp) Speed range: 29-32 knots 2 x Volvo Penta TAMD75P (2 x 480hp) Speed range: 31-33 knots
Engine Notes
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The General's likely got its party bus on call and decked out with Cristal, tequila shooters and the phone numbers of local talent (and their "representatives") on speed dial. The company made quick work of the 2007 North American Car and Truck of the Year awards, this morning, accepting awards for the Saturn Aura and Chevrolet Silverado. Among the cabal of journos who voted, the Aura edged out the Honda Fit and Toyota Camry, while the Silverado opened a carafe of bootstomp on the Mazda CX-7 and Ford Edge. The results were kept in "a mayonnaise jar on the front porch of Funk and Wagnalls until noon today, at which time Ed McMahon took a long pull on a bottle of Jim Beam and exclaimed, Hiho!
Jalopnik Reviews: 2007 Chevrolet Silverado / GMC Sierra, Part 1 [internal]


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Rule 17: Minimum Standards for Gun Locking Devices
17.1 Definitions (9 NYCRR Section 492.1)
As used in the Rule, the following terms shall mean and include:
Gun Locking Device means an integrated design feature or an attachable accessory that is resistant to tampering and is effective in preventing the discharge of a rifle, shotgun or firearm by a person who does not have access to the key, combination or other mechanism used to disengage the device.
Magnetic Key or Electronic Key means a magnetic or electronic device which is encoded with a unique magnetic signature or which emits a unique electronic signal that disengages a gun safety device or other safety feature of a weapon.
17.2 Standards Pertaining to the Characteristics, Design, Operation and Construction of Gun Locking Devices (9 NYCRR Section 492.2)
A gun locking device must:
- Open only by either a numeric combination, key, magnetic key or electronic key. Those devices that operate by means of a combination must require the entry of at least three variables of numbers, letters or other appropriate symbols entered in a specific sequence on a keypad, dial or tumbler device.
- Be constructed with such quality of workmanship and material that it may not be easily pried open, removed or otherwise defeated by use of common household tools.
A gun locking device must not:
- Be locked by means of a screw or screws.
- Have any exposed screws that, if removed, would render the gun locking device ineffective.
- Be disengaged by a handcuff key or common household tool.
- Be subject, at the time of sale, to voluntary or involuntary recall by the manufacturer.
17.3 Standards Pertaining to the Performance of Gun Locking Devices (9 NYCRR Section 492.3)
When properly applied, a gun locking device must be effective in preventing the discharge of a rifle, shotgun or firearm by a person who does not have access to the key, combination or other mechanism used to disengage the device.
17.4 Standards Pertaining to the Instructions for Use of Gun Locking Devices (9 NYCRR Section 492.4)
A gun locking device must be accompanied by written instructions on its proper installation and removal.
Authority: General Business Law § 396-ee.


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Accepting Co-Authors for this. But only if your an...
200 Reason Why I Love Hybrid9141520
- by Nitori Mikoshiba
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- Published: 6 Jul 2014
- Updated: 20 Jul 2014
- Status: In Progress
These are 101 reasons why I love Hybrid/Kai...I hope you forgive me...we are best friends infinityever
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Sir Paul McCartney joined the impressive roster of celebs greeting the crew of space shuttle Atlantis today, following Elton John and Michael Stipe's musical messages to space earlier this week.
Following a blast of Good Day Sunshine, McCartney chirped: "Good morning guys! Wake up! And good luck on this, your last mission. Well done!"
Suitably roused, the International Space Station's residents will now get back to even more box-shifting from the Raffaello multipurpose logistics module.
Commander Chris Ferguson, though, will first have to tackle a failed computer aboard Atlantis. The crew was woken last night by an alarm triggered by a problem with general purpose computer 4 (GPC 4).
Atlantis has five such computers, and the failure doesn't present much of a problem. NASA explains: "Only two of the shuttle's computers are needed when the shuttle is orbiting the Earth, so the functions that computer had been responsible for were simply transferred to another computer."
The agency adds: "While troubleshooting is underway on GPC 4, GPCs 1 & 2 are operating Atlantis' systems and GPC 3 is in a standby mode. The first step in today's procedure is underway, transmitting the memory of GPC 4 to Mission Control for evaluation."
Once they've done another hard day's work heaving boxes from Raffaello, the Atlantis and International Space Station Expedition 28 crews will have a chat with president Obama before turning in.
Here's NASA's video round-up of yesterday's action aboard the ISS, including an insight into the patriotic "All American Menu":
You can find the latest on Atlantis' last mission right here. ®


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Torrey Smith's brother dies in motorcycle crash
Wide receiver to play in Sunday's game
Ravens Nation rallied Sunday around Baltimore Ravens wide receiver Torrey Smith after the death of his younger brother.
Tevin Chris Jones, 19, died Sunday morning when his motorcycle ran off the side of the road and hit a utility pole in Westmoreland County, on the Northern Neck peninsula of Virginia.
Police in Virginia said Jones was wearing a helmet during the crash, and speed was not a factor. A cause remains under investigation.
Smith was notified at the Ravens' downtown Baltimore team hotel shortly after 1 a.m., and he left immediately to be with his family. He tweeted his grief Sunday morning.
"I can't believe my little brother is gone ... be thankful for your loved ones and tell them you love them ... this is the hardest thing ever. I can't say a bad thing about him ... proud to have him as a brother ... RIP Tevin."
Head coach John Harbaugh met with Smith before he left the hotel and issued this statement:
"This is devastatingly sad, sad news. Smith and his family are a close, special family, and our hearts and thoughts reach out to all of them. Our hearts ache today. We pray for Tevin, his mother, Torrey and the rest of the family. God bless Tevin."
During the day, it was unclear whether Smith would play in Sunday evening's home game against the New England Patriots. But come game time, he was suited up and hit the field after he said he got only one hour of sleep.
"It was tough. Emotionally, I didn't know how I would hold up," Smith told reporters after the game.
Not only did he play, Smith scored two touchdowns and had six catches for 127 yards.
"I didn't want to hurt my team. When I came here, the more I was grounded and the more comfortable I started to feel," Smith said. "I'm glad I came back up here. I think it helped me out."
"Thanks to my teammates and coaches and all the support from everyone around the league and just everyone everywhere. … I just thank everyone on behalf of my family," Smith said.


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As the third annual Women in the World Summit concluded on March 10 in New York City, A Daily Beast commenter on a blog posted:
"Most American women know how good they have it without visiting a third-world country where women are treated as pack animals. In America women are respected, revered and of course they have 'the vote'. The occasional leftie that hates America would be unhappy anywhere — it's really herself that she dislikes."
Indeed. The three-day summit amply illustrated how stark oppression against women can still be in today's world. Suma Tharu, a 16-year old who managed to escape indentured servitude in Nepal sang for the crowd at Lincoln Center while the "moral obligation to educate girls" around the world was discussed. It should be clear to any rational thinking person that women's rights in some parts of the planet have a long way to go. But, as the commenter points out, should American women be satisfied because in most cases they are "respected, revered" and have the right to vote?
The insurance industry was involved in the event. Paul Alexander, senior vice president of communications for Liberty Mutual Insurance introduced the "Responsibility Project: Women in Film" series, which immediately made me think of a feature I wrote for the March issue of National Underwriter Life & Health on the state of women in the insurance industry. What I found while conducting research for that article was that, although women comprise half of the workforce in the industry, they are vastly underrepresented when it comes to high-level executive positions.
The article, through the oral histories of women who are currently working in the industry, diagnosed a problem and discussed why it was the case without giving any one theory for it. (There isn't one.) But according to the commenter's logic, women in the U.S. should just be happy that they are where they are, that they are not overtly or institutionally mistreated, and go on with their lives. Any time they feel that there is an obstacle to their progression they should compare themselves to women in some of the poorest places on earth that are struggling with ancient cultural traditions that systematically oppress them.
I would dismiss the comment as the flawed logic of an obscure individual but I know that there are people out there who agree with the statement and are not able to see that the argument is riddled with defects.
The argument itself reminds me of an episode of The Sopranos, in which Tony Soprano gripes to his therapist, Dr. Melfi, that Americans are the only people on the planet that think that happiness is a right. "Just because we have surpassed the basic needs of food, clothing and shelter does that mean that we have no problems left?" Melfi retorts. "Maybe since we are not scrounging for our next meal, we have time to delve into the deeper problems of the human psyche."
It would appear, according to the commenter, that since women have overcome certain obstacles, they should become stagnant, and every time they feel pangs for greater things (to reach the top management level in an insurance company, for example) they should compare themselves to the child bride in Pakistan or to the indentured servant in Nepal. This notion is as asinine as it is self-defeating, and the degree to which the commenter and others subscribe to it is frightening. Expecting equality at the workplace is no mere first-world-problem. Indeed, it pales before the plight of women in other parts of the world, but to make that comparison as a means of deflecting the need to improve things here at home is less than productive. To let some accomplishments stymie further ones is, if nothing else, moronic.


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Venerable Copres of Palestine
Saint Copres was found as a newborn infant by monks of the monastery of Saint Theodosius in Palestine. He lay upon a dung-hill (in Greek "kopria"), where his mother left him during an invasion of the Hagarenes (Moslems).
The monks took the infant, named him Copres, fed him goat's milk and raised him in their monastery. Saint Copres later accepted monastic tonsure and spent his whole life in his monastery. Having attained to an high degree of virtue and the gift of wonderworking, Saint Copres died peacefully the age of ninety.


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diet, food and drink regularly consumed for nourishment. Nutritionists generally recommend eating a wide variety of foods; however, some groups of people survive on a very limited diet. The traditional Eskimo diet, for example, depended heavily on meat, but Eskimos ate nearly all of the animal; organ meats are rich in vitamins and minerals. Vegetarians exclude meat (and sometimes by extension dairy products) from their diet, often for philosophical reasons. Others exclude only red meat, but eat poultry and dairy products. To maintain a healthy diet, vegetarians need to eat a wide variety of plants whose nutrients complement each other, providing a balance of amino acids and vitamins.
Sections in this article:
The Columbia Electronic Encyclopedia, 6th ed. Copyright © 2012, Columbia University Press. All rights reserved.
See more Encyclopedia articles on: Food and Cooking


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Welcome to TORCommunity, your all-in-wonder SWTOR fansite for guides, databases, tools, and more!
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Hello all,
TORCommunity is looking for help in maintaining and update the site and databases. Since the day after it was announced in October of 2008, we've done our best to provide useful information to the community regarding the game. What started out with guides evolved into a robust database of information and other tools we hoped the community would find useful throughout their SWTOR adventure.
Unfortunately, like most games over time, the community of SWTOR has dwindled and most of our founding team has retired and moved on. Neverthless, we made a promise that we would support the game until its servers shut down, and we intend to keep that promise. Currently, we lose over a hundred dollars a month keeping the site running.
Thank you for all of your support over the years, and may the Force be with you.
- The TORCommunity Team
When I first started working on Star Wars?: Knights of the Old Republic? in my early days at BioWare, I knew we were making something amazing. It wasn't just the thrill of creating an RPG in the Star Wars? universe, or being able to bring the Old Republic setting to a wider audience. Right from the beginning, I knew that the character of Revan was something special ? a way for players to connect to the Star Wars universe and explore the duality of the light and dark sides of the Force? in a new way. Because of this, I was convinced almost from day one that KOTOR was going to be a hit.
Over the years, I've been asked many times about my role as Lead Designer on Star Wars?: Knights of the Old Republic?. I am forever grateful to have been part of that team and it's a team I am still proud to be a part of as many of us are still here at BioWare.
The Star Wars?: The Old Republic? team is excited to celebrate Microsoft's release of the original Star Wars?: Knights of the Old Republic? coming tomorrow, October 24th, to Xbox One.
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A well proportioned octagonal Nickel plated solid brass centre knob for the front door. This door pull is a very popular classic Victorian design. A similar version can be found on No.10 Downing street. Traditionally it is used in the centre of the door to pull and push the door and is fixed using a large bolt that passes through the door and fixes on the inside. This centre pull is available in a larger size and a Unlaquered polished brass finish.
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Events , Governance & Risk Management , Incident & Breach Response
Data Breach Summit Kicks Off in BengaluruSecond Edition Of ISMG's Global Summit Sees Firm Traction
Risk-oriented security and resilience are the cornerstones of a future-proof strategy for the enterprise today. With Indian enterprises increasingly going digital, this is the core message upon which ISMG's second Data Breach Summit focused. The event kicked off today at the Taj West End, Bengaluru.
See Also: 451 Research Report: Tackling the Visibility Gap in Information Security
Technology alone is not enough to tackle the constant threat of data breaches today, said the summit's keynote speaker, Dr. A. S. Ramasastri, who is director at IDRBT. Focus on governance, policy, skills and robust ecosystems are the urgent priorities. The topic for his keynote session was "Managing Data Breaches: Assembling the Jigsaw Puzzle."
"The need of the hour is to emphasize on areas like online big data analytics system and digital forensics. Crime investigation in the digital world also needs to be improved," Ramasastri added. He also highlighted the need to have a hybrid security model, which spans across the corporate, sectoral, national and global levels.
This is especially the case in India, given the lack of any kind of mandated disclosure, despite the increasing number of attacks being reported in the wild by practitioners. Challenges in managing data breaches leveraging the latest vulnerabilities and vectors means that organizations must look beyond the traditional approach to security, which is still where the Indian marketplace is evolving from, experts at the summit say.
Key Messages
Against the backdrop of the year 2015, which set a benchmark for breaches and proved that any data of any perceived value is at risk of being targeted, Indian organizations must recognize the need for a practical, risk-based approach, which was one of the key messages at this summit.
The lineup of speakers and the different areas being addressed distinguishes the event, says Biju Tilak, mobile security strategist, IBM Security. "A complete and holistic takeaway is of great value. The community needs more collaboration and a platform like this aggregates all these core issues and disseminates them to the community at large, which I feel is of great value," he says.
Tilak was a speaker at the summit today and spoke on the mobile vulnerability landscape in Indian enterprises.
The second key message that set the tone for the conversations was: How to survive attacks and thrive in the face of them, given that these threats aren't going away.
"I hope that the Data Breach Summit will provide us with a lot of insights around how to tackle the emerging threats around areas like cloud and mobile. Another area of interest for me is how the banking sector will embrace the transition to virtual payment systems," shares Mahesh Kalyanaraman, Deputy General Manager, Corporate Security, Tata Communications.
Participants such as Manoj K Sarangi, Vice President, Chief Information Security Officer, HCL are looking for "actionable information."
"We hope that the Summit sets the right environment which fosters a meaningful discussion in the industry," added Sudeep Kumar Das, Lead-Sales Engineering, EMC India.
Hot Sessions
Other themes at the event include security of critical infrastructure and a fresh look at emerging threats, with a specific focus on the Indian context. Legacy strategy and mindsets mean that practitioners are constantly fighting off the omnipresent and relentless waves of successful targeted cyberattacks. Dr. Ramasastri's session provided an overview of the different elements that go into the management of a data breach in India.
Some of the other speakers included Shree Parthasarathy, Partner and National leader for cyber risk at Deloitte, who shared recommendations on making the threat intelligence available to organizations; and Shivakumar Sriram, who talked about securing payment innovations taking place in the country. Sivakumar is Chief Risk Officer South Asia at VISA.
This summit is the first in this series this year, with the second being planned in June at Mumbai, and others across the country subsequently. You can get more information on ISMG's Data Breach Summits here.
Additional Summit Insight:
Hear from more industry influencers, earn CPE credits, and network with leaders of technology at our global events. Learn more at our Fraud & Breach Prevention Events site.