text:
O Lord, Who Gave Thy Life for Me
O Lord, who gave Thy life for me, I come now in hu –
mil - i - ty And here my sac - ri - fice im - part: A
con- trite soul, a bro - ken heart. Oh, may Thy love in
mer- cy shine And bind my sor - r'wing heart to Thine.
2. Up - on the al - tar here I lay My pride, my hurt, each
will - ful way, My bur - den all of sin and care, And
in its place Thy yoke I'll bear. Oh, may Thy love my
soul re - fine And bind my trust - ing heart to Thine.
3. My heart is full of love for Thee Be - cause I know Thou
first loved me. Now by that love I'll seek to live And
free - ly, like Thy - self, for - give. Oh, may Thy love my
life de - fine And bind my will - ing heart to Thine.
4. And as I strive to thus en - dure With clean - er hands and
heart more pure, In all a - round I see Thy face And
feel the boun - ties of Thy grace. O Sav - ior, may Thy
love di - vine Now bind my grate - ful heart to Thine.
Text: Alice Johnson
Music: Alice Johnson
Artist: Johnson
Album: Music Published in the Church Magazines: Ensign
Composition Date: 2012-10-02
More Info: Ensign


text:
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subset: commoncrawl


text:
Panasonic VW-CLT2 3D Conversion Lens Review
Contributions by Jamison Cush
Before camcorders with native 3D capabilities became prevalent, Panasonic started off its consumer 3D video push by introducing the VW-CLT2 3D conversion lens. Attaching to the front of select Panasonic camcorder models (in the case of this review, it was tested on a Panasonic V700M) the VW-CLT2 features two lenses to split the image and create a 3D effect (though there is still only the one image processor of the camcorder). So how does it fare compared to more recent 3D home video solutions?
Build & Design
The VW-CLT2 adapter is, put simply, clunky. Never mind the fact that a camcorder with built-in or native 3D capabilities would have a far more graceful appearance, because even for an add-on attachment, this adapter has a cumbersome design.
The entire thought process behind this attachment puzzles me. The adapter is not compatible with all Panasonic camcorders; rather, specific camcorders are designed for it. That's fine, I don't necessarily fault the company for that. What I take umbrage with is that despite that decision, Panasonic did not design the compatible camcorders in such a way that the adapter could just plug straight onto it. Instead, users have to first apply an intermediary ring that screws onto the front of the camcorder and then they can plug the actual adapter into said ring and lock it into place. The whole thing is not only clumsy, but it adds to the amount of stuff sticking off the front of the camcorder.
And on that note, it's worth pointing out that yes, such an awkward approach to 3D does result in a noticeable amount of added weight. Given that the camcorder I tested it out on, the HC-V700M, is relatively lightweight, the 3D adapter just made the entire unit feel front-heavy in my hand. And, of course, the attachment makes the entire unit a good four inches longer, greatly reducing its compactness.
In terms of its actual build quality, the VW-CLT2 feels a little cheap, as it's primarily made up of plastic parts. Perhaps this is for the best, however, as metal or a higher-quality material probably would have just added even more weight to the entire affair.
There is a flip-open panel on the top of the unit that reveals two plastic dials that move the two lenses of the adapter left, right, up, and down. These knobs are used for calibrating the 3D effect before recording. Before turning on the camcorder, the front lens cap for the adapter, which has guidelines drawn on the inside, must be placed on the unit.
Users must then turn on the camcorder and use the dials to adjust the horizontal and vertical position of the lenses until the on-screen guidelines match up with those on the inside of the lens cap. It's a hassle that the 3D effect has to be calibrated manually, and the instruction manual suggests that you do it every time before recording. It's only after doing this that the camera enters an auto-calibration mode where you select an object roughly four feet from the camera and hit 'adjust' to finalize the 3D effect settings.
First and foremost, there are a number of limitations when using the VW-CLT2 conversion lens. What stands out most, perhaps, is the fact that users cannot zoom when using the adapter, which is a restriction that you?d be hard-pressed to find on newer 3D camcorders. There's also the fact that the distance between (and angles) of the two lenses cannot be adjusted, which is an important feature that would allow users to adjust the 3D effect.
And finally, I have never experienced as much sensitivity to movement or panning as I did when using the camcorder with the adapter attached. Anything more than very slow, deliberate movements of the camcorder would cause it to throw up an alert saying that I was panning too fast, resulting in motion blur (and an ultimately disrupted 3D effect). It's probably not a good sign that even in the instruction manual, Panasonic warns against moving the camcorder too much while recording and even recommends just using a tripod.
If you're shooting and you find that you?re experiencing trouble with the 3D effect, there is a quick calibration option that's added to the camcorder's touchscreen menu when the conversion lens is attached. Pressing the button essentially skips over the manual calibration process that involves matching up lines with the inside of the lens cap and takes you to the part where you pick a subject four feet away.
So does it work and produce 3D video and stills? Yes, it does, to a degree. We tested it on a 50-inch Panasonic 3D HDTV with Panasonic glasses, and our footage was there on display in what could be described as three glorious dimensions. But before you get deluded into thinking you will shoot the home video equivalent of Avatar with the VW CLT-2, there are significant limitations with the image quality and effect.
For starters, the color reproduction is extremely drab, the video quality grainy, the 3D effect minimal. Of course, the image grain isn't as big of a deal on a smaller display ? but then the already limited 3D is minimized by the display edges.
3D images should have three levels, with images appearing to come out from the display, in level with the display, and back 'inside' the display. With our test footage, images only popped out slightly, and it's only noticeable if you are looking for it. It would be impossible to recreate those 3D movie moments when a viewer instinctively covers his or her face as an object comes flying out at them.
Compounding any image quality issues is that fact that too many users do not know how to shoot 3D properly. Good 3D requires forethought in order to avoid ghosting or image splitting, and in setting a proper baseline level and no image interruptions from the edge of the frame, which can completely ruin the effect. It?s almost impossible to shoot spontaneous good 3D.
On the one hand, it's difficult to fault Panasonic for the VW-CLT2 Conversion Lens' shortcomings, as it was released a while ago as one of the first consumer products on the market that allowed for shooting 3D home video. But the fact remains that, now that time has passed, there are better options out there, including camcorders that have native 3D capabilities rather than requiring an adapter.
These options, aside from providing a much less clumsy design than the VW-CLT2, also provide a greater 3D effect and maintain video quality rather than devolving into a grainy mess in the conversion process. And to top it off, the VW-CLT2 has an unappealing price tag of $269.99 for an extremely inferior product, so we highly recommend that you look elsewhere.


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RSL MATCH PREVIEW & NOTES: REAL SALT LAKE v. CHIVAS USA – SATURDAY, MARCH 24
"MLS Class of 2005" Cohorts Renew Acquaintances with 7:00 p.m. MT Kickoff at Rio Tinto Stadium
SANDY, Utah (Friday, March 24, 2012) – Real Salt Lake (2-0-0, 6 pts.) will look to maintain its perfect start in 2012 tomorrow, Saturday, March 24, when it will play host to Chivas USA (0-2-0, 0 pts.) in the second home match of its 2012 MLS regular season slate. Kickoff at Rio Tinto Stadium is set for 7:00 p.m. MT, while the festivities at RSL's Sandy "fortress" will begin at 5:00 p.m. with the opening of the Carnival Real pre-game festival on the stadium's East Lawn.
While tickets for the Real Salt Lake-Chivas USA contest remain available, with redemption for the Seven Peaks' "Pass of all Passes" taking place on Saturday morning fans are advised to purchase their tickets in advance via the Zions Bank Ticket Outlet on RealSaltLake.com. Fans that can't make it to Rio Tinto Stadium can watch the proceedings live in high-definition on CW30, the broadcast starting at 7:00 p.m. and concluding with a 30-minute post-game wrap-up show at 9:00 p.m. Fans will also be able to listen to the action live via the team's official radio partners: ESPN 700/ESPN700Sports.com, La Gran D 102.3 FM and Juan 1600 AM.
Real Salt Lake's roster has been inching back towards full health since the start of the campaign two weeks ago, with MF Javier Morales and FW Álvaro Saborío both upgraded to probable for tomorrow's contest and DF Nat Borchers and MF Will Johnson listed as questionable, while only FW Cody Arnoux (L adductor strain) is completely ruled out of action. Chivas USA enters the "MLS Class of 2005" reunion against RSL coming off a pair of tough 0-1 defeats at home and will likely be without the services of star striker Juan Pablo Ángel, who is still suffering from concussion-like symptoms after missing last weekend's defeat against Vancouver Whitecaps FC.
How to Follow Real Salt Lake vs. Chivas USA
- TV: CW30 (30-minute post game show at 9:00 p.m.); live on MLS Direct Kick subscription package (available on DIRECTV, Dish Network, iN DEMAND L.L.C., and Avail-TVN)
- Radio: ESPN 700 (pre-game coverage begins at 6:00 p.m. MT), La Gran D 102.3 FM & Juan 1600 AM
- Online: Live updates via the @RSLkickoff gameday Twitter Feed and MLS MatchCenter on RealSaltLake.com, and streaming video available via MLS Live on MLSsoccer.com (subscription required)
MLS Game Guide for Real Salt Lake vs. Chivas USA Available Online
Following are links to the Adobe PDF and Issuu.com online reader versions of the Major Leagu Soccer Game Guide (media notes) in advance of Saturday's match against Chivas USA at Rio Tinto Stadium. If you have any problems viewing or downloading the documents or are seeking more information on the match, please contact John Koluder in the RSL Communications Department via email at firstname.lastname@example.com.
Click here to download the PDF version of the RSL Game Guide
Click here to browse the RSL Game Guide online via the Issuu.com reader
RSL History v. Chivas USA
While RSL enters Saturday's affair against Chivas USA trailing 7-9-4 in the all-time regular season series, most of that damage was inflicted in the early years of the rivalry, as the Claret-and-Cobalt are undefeated in their last five contests against the Goats (4-0-1) dating back to 2009. RSL is 4-2-3 against Chivas USA at home, including last year's 1-0 win (Johnson 87) on May 7 that was infamously marred by a horrific left ankle injury suffered by MF Javier Morales that kept the RSL playmaker sidelined for the next four months. The Utah side would also post a favorable 1-0 result in the second meeting of the season on August 27, FW Álvaro Saborío's 11th minute goal holding up despite RSL having to play a man down for the final 66 minutes.
www.RealSaltLake.com / www.RioTintoStadium.com / www.ESPN700Sports.com


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Today, the NCAA filed its post-trial brief, which summarizes the legal and factual arguments the Association made during the O'Bannon trial. In sum, the plaintiffs' failed to meet their burden of establishing that the challenged NCAA rules violate antitrust laws.
It is the position of the NCAA, as argued in the brief, that the rules that have been challenged in this case are essential to preserving amateur college sports in the United States, which are unique and distinct from professional sports. This position is supported by longstanding Supreme Court precedent. The Supreme Court clearly stated in 1984 that the fundamental principle of amateurism – that athletes not be paid for their performance – is at the core of what distinguishes college sports and that it is essential that the NCAA adopt and enforce rules such as this that preserve the revered tradition of amateurism. The economists hired by plaintiffs' lawyers acknowledged that every other amateur sports organization has rules that prevent athletes from being paid to play. The NCAA is no different, and its amateurism rules are entitled to deference under the antitrust laws.
The plaintiffs did not meet their burden at trial to show that the NCAA's rules violate the law. Under applicable antitrust law, the plaintiffs needed to define a "relevant market" in which the alleged damage occurred. They were unable to identify that market even on the last day of trial and in their post-trial brief. The plaintiffs also were required under the law to show both anticompetitive effects and antitrust injury which they failed to do.
Even if the plaintiff's had established a satisfactory case, which they did not, and the burden shifted to the NCAA to demonstrate that its rules result in procompetitive benefits, there was substantial evidence at trial supporting four procompetitive benefits:
- Rules Maintain NCAA's Unique Amateur College Football and Men's Basketball Product
- Rules Increase Output of Division I Men's Basketball and FBS Football
- Rules Promote Competitive Balance
- Rules Promote the Integration of Athletics and Academics
- Any one of these would provide legally defensible justification for the rules the plaintiffs have challenged.
The plaintiffs also failed to prove that there is a "substantially less restrictive manner" for achieving these procompetitive benefits without "significantly increased cost" as is required under an antitrust analysis.
Finally, there was no evidence presented at trial, or over the several years that this case has been litigated, that would provide a basis for the Court to grant an injunction related to the NCAA's ability to enforce its rules that would be supported by antitrust laws.


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Surrey business and community groups are launching a new campaign to get light-rail transit on track for south of the Fraser.
The Surrey Board of Trade announced a new coalition — Light Rail Links — which is joining the call for an LRT solution to the region's lack of rapid transit infrastructure.
Mayor Dianne Watts has been pushing for years without success for approval of an LRT line rather than a SkyTrain option. She wants to see three light-rail corridors connecting Surrey town centres: one between City Centre and Guildford, along 104th Avenue; one connecting City Centre to Newton, along King George Boulevard; and one connecting Surrey to Langley along the Fraser Highway.
Without new transit investment in the near future, Board of Trade CEO Anita Huberman said, "our ability to attract businesses to Surrey will be compromised. If we don't have good transportation, which is the foundation of our economy, it will suffer."
Increased traffic in Surrey as the population grows is a very real threat, she added, noting it took her 50 minutes by car to get from South Surrey to the Board of Trade office at 104th and 144th Avenues.
Light Rail Links stressed that Surrey — the fastest-growing municipality in the region — is expected to grow 50 per cent to 750,000 residents by 2041. Yet it has not had any significant transit infrastructure in almost 20 years. Less than seven per cent of the $6.6 billion spent on rapid transit in the Lower Mainland has gone south of the Fraser.
Surrey residents are fed up with the lack of action on transit, said Elizabeth Model, CEO of the Downtown Surrey Business Improvement Association.
"Everyone is frustrated. We're the last one in the pecking order [to get transit upgrades], but we're the largest economic engine in the region."
The bus-based system is unworkable for residents without cars, said the Surrey Crime Prevention Association's Karen Reid Sidhu.
"Youth are struggling to get around the city," Sidhu said, noting her 240 youth volunteers find it hard to make it to their commitments via transit. It takes some up to 11Ž2 hours by bus to get from Central City Shopping Mall to Cloverdale.
Mayor Watts said it was time for city residents to speak up.
"They need to let their voices be heard," she said in an interview.
From government and TransLink, Watts said, "there needs to be a recognition that in Surrey, we are building a city. Seventy per cent of growth is coming from south of the Fraser and we need that infrastructure."
Scott Olson, a realtor and past president of the Fraser Valley Real Estate Association, said light rail was also the cheaper option.
"For the price of one extension of SkyTrain, we could create a complete infrastructure with LRT."
The group estimates an LRT line costs 1.5 to 3 times less than a SkyTrain extension.
Fleetwood Community Association President Rick Hart said commuters and seniors in his neighbourhood were poorly served: the Fraser Highway B-Line is often full when gets to Surrey via Langley, and buses and SkyTrain presented mobility and safety issues for seniors.
"LRT is something that will assist those people and help them age in place," he said.
Other citizens' groups have already been working on the issue. The Rail for the Valley Society has been advocating for a light-rail passenger train system running on the existing Interurban line out to Chilliwack.
But not all Surrey community member endorse light rail.
The citizen's group Better Surrey Rapid Transit makes a case for SkyTrain as the better option for the region, arguing LRT will get half the ridership of a new SkyTrain line and will continue to cause congestion as it runs along existing roads.
"Current options look forward to this city's transportation needs to 2041 ... but do not look forward to what the needs will be in 30-50 years and beyond," Better Surrey Rapid Transit member Daryl Dela Cruz said in an email.
"We want to tell Mayor Watts and TransLink that the solution that Surrey needs is bigger than what everyone wants, and we're advocating for that bigger solution that Surrey needs – an expansion of SkyTrain."
Learn more about Light Rail links at www.lightraillinks.com.
Learn more about Surrey's light rail plans visit www.surrey.ca/RapidTransitNow.


text:
This vendor-written tech primer has been edited by Network World to eliminate product promotion, but readers should note it will likely favor the submitter's approach.
Ever since VMware bought Nicira last July the term software-defined networking (SDN) has taken off, with players like Cisco, Juniper, VMware and even HP and IBM jumping on the bandwagon.
SDN represents virtualization's evolutionary step from the server to networks. It is an emerging architecture that separates the control plane from the data plane in network switches and routers. SDN uses dynamic UDP (User Datagram Protocol) tunnels that are very similar to GRE (Generic Routing Encapsulation) tunnels, except that they can be turned on and off dynamically. SDN can be contrasted with traditional networks in which the control and data planes are jointly implemented.
TECHNOLOGIES TO WATCH IN 2013: Cisco products, more maturity for SDNs
The big advantage of SDN is that it lets you rapidly and dynamically carve up your network as you see fit. Why does that matter? Just picture today's typical programmer who thinks he's working on a development system. But unbeknownst to him, a faulty configuration has him actually working on a live production system. One simple typo could devastate the production system -- and therefore the entire business. SDN can solve this problem. The programmer can create a development system isolated in the sandbox, and then in two weeks instantly convert it to a production system.
Sounds abstract? Lets explore an analogy. When I drive my car from San Francisco to Los Angeles I take highway I-5 South -- a public road open to everyone. That represents today's network. With SDN, it's as if an engineer could quickly and inexpensively create private on-ramps, highways and exit lanes for each individual driver. And the engineer can authorize only some to get on and off. You can imagine the driving pleasure and efficiency with that type of road travel system. To do the equivalent in a traditional network would immediately become a cost-prohibitive nightmare.
What you lose: visibility
The only major drawback to SDN is you lose all visibility into your network traffic, making troubleshooting nearly impossible. As an example, imagine your users complaining about slow access to a database. Prior to SDN, the network team could quickly spot, for example, that a backup was slowing the network. The solution would be to simply reschedule it to after hours.
Unfortunately with SDN, you can see a tunnel source and a tunnel endpoint with UDP traffic, but crucially you cannot see who is using them. You cannot know if the culprit is the replication process, the general ledger, the email system or something else. The true top talker is shielded from view by the UDP tunnels, which means that when traffic slows and users complain, you can't readily identify where the problem lies in the network. With the loss of visibility, troubleshooting is hindered and a delay in resolution could be quite detrimental to the business.
What can you can do to stay ahead of SDN problems
Network engineers need to know about such problems, plan for them and have a tool to address them. Fortunately, some network performance management solutions let you know how packets are physically flying around the network and the logic behind the traffic. They can provide the best of both worlds as you get to see the physical network and peek inside the encapsulated SDN tunnels.
With insight into interactions among various virtual machines on each physical host, you can monitor all application traffic traversing the virtual switch, providing real-time and historical visibility into virtualized and private cloud environments. And once the packet and flow data is captured, it can be analyzed to detect end-user experience issues, TCP errors (retransmits, resets), server delay, top talking VMs, utilization and more. This is nirvana for the network manager who is now able to identify problems in the virtual network in a familiar fashion as he does in the physical network.
Love it or hate it, SDN is coming to networks everywhere, so network engineers need to determine where and how best to use the technology as well as consider how to address the network visibility challenge it imposes.
Read more about lan and wan in Network World's LAN & WAN section.


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- Codes: IS0195 M75805
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GROHE Essentials Glass 40 372 000Glass
Free delivery in 3-5 working days
5 years guarantee
Grohe AG is Europe's largest and the world's leading provider of sanitary fittings under one brand. As a global brand for sanitary products and systems, GROHE relies on its brand values quality, technology, design and responsibility in order to be able to offer "Pure Freude an Wasser". GROHE Quality is more than just a promise. It is a guarantee that all of our products meet and exceed the expectations of our customers by delivering a range of unique water experiences. Our customers rely on our products to perform throughout the day, every day. They are our toughest critics and our best informants. Quality is what sets GROHE apart. The consistently high standard of our products in every category and price range has cemented our reputation as the best value, premium brand within the sanitary industry. "At GROHE we believe quality is defined by the highest levels of craftsmanship, outstanding durability, high levels of functionality, long-lasting design and convenience of use. We work hard to inculcate quality everywhere in our business, in the products we bring to market and in the strategies taking us into the future." GROHE products are designed to last and we rigorously test them to guarantee their longevity. This is a core characteristic of the GROHE brand. Our products are engineered by the most experienced designers and research & development professionals in the industry and all our products are tested for a 15-year lifespan. GROHE's internal testing processes are among the most gruelling in the industry. None of our competitors invest as much in product testing and product life testing. Design at GROHE goes beyond good looks, touch and aesthetic messages. GROHE products have been designed to inspire, form a connection and create an intuitive understanding with the user. Stimulating dialogue and exchange with our customers is precedent. Design is a fundamental pillar of the GROHE strategy to deliver the perfect balance of superior technology, quality and design. These three core values are evident in all our products and remain a fundamental part of our design philosophy. This is the basis of why and how we create unique ways in which to enjoy water.
Modern, timeless and with wide-ranging appeal, accessories in the Essentials range add the final touches to your bathroom. Created to coordinate with a wide range of faucet styles, the collection benefits from our striking GROHE StarLight® chrome finish.
MA Bath Ltd
The Courtyard
Call us on: 0756 290 7028
Registered in England and Wales.
Registration number: 8854876
The Courtyard
Call us on: 0756 290 7028
Registered in England and Wales.
Registration number: 8854876


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Oh Dear! Too Many Deer in Rural Japan
Rural Japan is being over-run by deer that are damaging crops and timber groves. But there's another problem, too: a shortage of deer hunters. WSJ's Chester Dawson reports from Bungo-Ono. (Photo: Corbis)
This transcript has been automatically generated and may not be 100% accurate.
I ... girls Japan hunt is on ... the targets of the country many dear ... he's here being over Iran ... it's getting worse ... in addition to these were the deer population is another ... a shortage of deer hunters ... the average age of Japanese hunters is now over sixty five ... is young people from the countryside continue flocking to the city ... income eyes get more strange ... the decline in the Hunter population due to aging ... is the biggest problem ... increasingly tough gun regulations make it difficult to attract young people ... the deer problem is resulting in lost crops and timber were it's ... it's so bad that the government is considering entered the Seawolves to serve as natural predators ... the grim reality is that the financial toll is mounting ... in Mona Syria's it's getting impossible the harvest ... even if yields are fenced off the deer breakthrough ... for Japanese urbanites charging three the money for it holds little appeal ... another big challenge is getting young people to ... tennis ... Devinder cooking classes like this one in central Tokyo in recruiting year meat consumption to a new generation ... it's a tough sell ... on ... here are two cute of an animal to eat ... that's a sentiment could do themselves can surely get behind ... for the law Street Journal this is Mark Scheffler ...


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Julianne Hough Bobby Pin Hair | Met Gala 2013
Behind the Scenes at the Met Gala: Julianne Hough's 100-Bobby-Pin Updo
Clad in a spiderweb-inspired frock by Topshop, Julianne Hough's Met Gala hairstyle was set to mimic the latticework design of her ensemble. In fact, celebrity stylist Riawna Capri used over 100 visible black bobby pins to secure the star's pompadour updo. The effect was edgy and modern, with the dark pins providing a striking contrast to Julianne's flaxen strands.
To achieve the style, Capri began by prepping Julianne's wet hair with Vidal Sassoon Pro Series Foaming Air Mousse ($5). Her strands were then blown out with a round brush, and a small dose of firm-hold gel was applied throughout. Next, Capri took one-inch sections to create a series of three ponytails on each side of Julianne's head. Loose pieces of hair were secured with the bobby pins in a creative fashion to form a tight style. To finish, Capri molded Julianne's bangs into a pompadour, securing at the back in a crisscrossed pattern. A few spritzes of Vidal Sassoon Extra Firm Hold Hair Spray ($5) to finish lent the perfect amount of punk rock lasting power.


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The opinions expressed in this commentary are solely those of Paul R. La Monica. Other than Time Warner, the parent of CNNMoney, Abbott Laboratories and AbbVie, La Monica does not own positions in any individual stocks.
Remember how stocks did nothing but go up all the time? That's so 2013.
Volatility is back. Investors are growing increasingly jittery about geopolitical flare-ups in Ukraine and Gaza (and beyond). People are worried about market valuations.
The CNNMoney Fear & Greed Index is at the Extreme Fear level of 6 and can't go much lower! (There is no such thing as a negative reading.)
I wrote last week about how long-term Treasury bonds have outperformed stocks this year. Since then, bond prices have climbed further (sending yields down) and stocks have fallen a bit more. It shows that investors are craving safety.
But rushing into bonds and ignoring stocks because of short-term risks is not a smart move for the long haul.
Related: 5 big retirement mistakes
"History says that when investors get nervous, that is a reasonable time to go the other way. Selling when stocks are down is the opposite of what you should be doing," said Patrick Kaser, a managing director for Brandywine Global. "Investors have to retrain their brains to think of a longer-time frame."
Exactly. I said as much last week in the video below.
So now's the time (Paging Charlie Parker! Bebop fans will be rewarded at the end of this column) to be looking at blue chip, dividend-paying companies that can hold up well during rocky periods for the broader market.
Kaser likes industry giants such as Cisco (CSCO), Microsoft (MSFT), GM (GM), JPMorgan Chase (JPM), Citigroup (C) and Metlife (MET).
All six stocks pay dividends and five of them (Citi is the exception) have dividend yields that are greater than the 2.45% yield on the 10-year Treasury.
Related: Small stocks are sinking
They are all bargains as well. The three financials and GM each trade for less than 10 times 2015 earnings estimates. Cisco and Microsoft are valued at 12 and 16 times forecasts for 2015 profits, respectively.
"We're not invested in these stocks just because they are big. We're in them because they are cheap," Kaser says.
Mark Eveans, chief investment officer of Meritage Portfolio Management, also is favoring larger, brand name stocks. His firm owns tobacco titan Altria (MO), semiconductor leader (INTC) and defense contractor Lockheed Martin (LMT) in its Meritage Yield-Focus Equity fund.
Intel and Lockheed pay dividends that yield more than 3%. Altria's stock has a yield of 4.5%.
Related: The 4 biggest mistakes investors are making
Eveans says these kinds of companies offer protection for investors in uncertain times. They all have strong balance sheets -- so you can count on the steady dividend payments even if the stock prices don't rise all that much.
"If the broader market sluggishness continues, high-yield stocks should do well over the long-term," he said, adding that "dividends should play a bigger role in any investment strategy."
Eveans is hopeful that the recent market pullback will also make companies think twice about using cash to buy back more stock. Share repurchases are often viewed as a good thing by investors because it's an easy way to improve earnings per share since it lowers the share count.
Related: 5 reasons why the stock market won't crash
But a dividend is tangible. It's actual money an investor can use to buy more stock ... or other things that could help boost the economy.
Eveans also advises investors to think globally. His fund owns British drug maker AstraZeneca (AZN), Canadian banks Toronto-Dominion (TD) and Bank of Montreal (BMO) as well as Australian financial firms National Australia Bank (NABZY) and Australia and New Zealand Banking Group (ANZBY).
Kaser said investors need to think beyond the U.S. as well. His firm owns China Mobile (CHL) and Toyota (TM).
Related: China stocks are back from the dead
Of course, none of these stocks will be immune from broader macroeconomic trends. But if you are willing to buy the argument that what's going on now may be nothing more than the start of a healthy correction and not the second coming of 2008, then sticking with blue chips is a way to help you sleep better at night.
As any halfway-decent poker player knows, you don't fold your hand when you've got good cards.
Reader Comment of the Week ... and The Buzz is going on a late summer hiatus! It's a bit strange to me to see so much anxiety about this market "slump" since the S&P 500 is still just 3% from its all-time high. But one Twitter follower hopes to profit from this "panic."
Well-played. Good luck with Pfizer (PFE). And bonus points for this Godfather of Soul video following my tweet on Coach (COH) and Michael Kors (KORS) earnings!
Anyway, I hope everyone enjoys the dog days of summer. I'm off tomorrow and the next two weeks. So I'll be back on Twitter on 8/25 and will have a column on 8/26.
Sorta sad to be missing Cisco earnings next week. So I'll get this out of my system. CAYSH!
And for those of you who have stuck around this long due to the promise of a Bird video, I am a man of my word. Enjoy.
This article was published in the October issue of Money magazine.
Searching for stocks that are likely to thrive in 2014? If recent history is a guide, one place to look is among shares that are badly lagging the S&P 500 this year.
Best Buy (BBY) and Hewlett-Packard (HPQ), after all, are soaring after MOREPaul R. La Monica - Oct 14, 2013 10:45 AM ET
The opinions expressed in this commentary are solely those of Paul R. La Monica. Other than Time Warner, the parent of CNNMoney, Abbott Laboratories and AbbVie, La Monica does not own positions in any individual stocks.
The Dow Jones industrial average hit a new all-time high today, topping the 14,200 level for the MOREPaul R. La Monica - Mar 5, 2013 12:00 PM ET
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|100% Clear (Platinum)
|This is the platinum trophy and is unlocked automatically when all trophies have been unlocked.
|Advanced Cooperation (Bronze)
|With different users controlling the pitcher and fielders, complete a strike 'em out throw 'em out double play.
|Batting Performance Evaluated (Silver)
|As a Batter in RttS, have 3 or more 'Good' or better At Bats in a single game at the MLB Level.
|Beat LA (Gold)
|Beat the Dodgers. Must be completed vs. the CPU with both pitching and batting set to Legend. RttS excluded.
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|Place in the top 33% in any single week of Challenge of the Week.
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|After falling behind in the count 0-2 work back to full count. Completed vs. CPU with both pitching and batting set to All-Star or higher difficulty.
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|Compete in the Challenge of the Week in back to back weeks.
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|Hit a Home Run to dead center in Coors Field.
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|In any mode get an inside the park Home Run. Must be completed vs. the CPU.
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|Pick off the CPU runner on 1st.
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|In any season mode, hit a Home Run on Mother's Day with a pink bat.
|Patience... (Bronze)
|Draw a 4 pitch walk in any mode. Must be completed vs. the CPU on All-Star or higher difficulty.
|Peak Training (Gold)
|In RTTS, reach level 5 in all training modes as a pitcher or a batter.
|Pesky... (Bronze)
|In any single at bat, see 10 or more pitches. Must be completed vs. the CPU on All-Star or higher difficulty.
|Pitching Performance Evaluated (Silver)
|As a Pitcher in RttS, in a single game, face 6 or more consecutive batters achieving a 'Good' or better rating at the MLB Level.
|Poor Billy... (Bronze)
|Win a game on an error.
|Psychic (Gold)
|With Guess Pitch on, in any mode, correctly guess 10 pitches in a row (Location OR Pitch) vs. the CPU on All-Star or higher difficulty.
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|In a single game, steal 3rd twice. Must be completed vs. the CPU.
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|Make 5 or more errors in a single game.
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|In RttS, earn more than 20,000,000 over the course of your career.
|The Billy Goat (Bronze)
|In Season or Franchise mode, win World Series as the Cubs. Must be full 9 inning games, simulating of World Series games will invalidate the trophy.
|Today... I am the greatest (Gold)
|In any mode, with any single player, accumulate 130 or more stolen bases in a single Season.
|Tough Loss (Bronze)
|As the away team, take a shutout into the bottom of the 9th and lose the game. Must be completed vs. the CPU.
|Yankees 'Inhale Deeply Through The Mouth'! (Gold)
|Beat the Yankees. Must be completed vs. the CPU with both pitching and batting set to Legend. RttS excluded.


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Monserate Chapter, NSDAR
Fallbrook, California
Any DAR member age eighteen through thirty-five years (until her thirty-sixth birthday) is a Junior Member. She holds full DAR membership and may serve as an officer or chairman at the national, state, and chapter levels. The California State Society prides itself on its many active Junior Members at all levels of the Society. The goals of the National Junior Membership Committee are to:
Pages, also known as the "Ladies in White," serve the Society at the California State Conference, council meetings, teas, and other California State Society events. They help the meetings progress smoothly by running errands, opening doors, answering questions, and assisting the California State Board of Directors and guests. A DAR member is eligible to serve as a page until her forty-first birthday. Paging is a fun way to learn more about DAR, make long-lasting friendships, and support the National and State Societies.


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SRD:Helm of Underwater Action
From D&D Wiki
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Helm of Underwater Action: The wearer of this helmet can see underwater. Drawing the small lenses in compartments on either side into position before the wearer's eyes activates the visual properties of the helm, allowing her to see five times farther than water and light conditions would allow for normal human vision. (Weeds, obstructions, and the like block vision in the usual manner.) If the command word is spoken, the helm of underwater action creates a globe of air around the wearer's head and maintains it until the command word is spoken again, enabling her to breathe freely.
Faint transmutation; CL 5th; Craft Wondrous Item, water breathing; Price 24,000 gp;Weight 3 lb.
Back to Main Page → 3.5e Open Game Content → System Reference Document → Magic Items


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Mormon church lowers age limit for missionaries
The Mormon church will lower its minimum age requirements for missionaries from 19 to 18 for men and from 21 to 19 for women, the faith's president announced Saturday.
Thomas S. Monson said at the church's 182nd semiannual General Conference that the historic change is expected to significantly increase the missionary force of The Church of Jesus Christ of Latter-day Saints - currently more than 55,000 worldwide.
The new age requirements will take effect immediately and replace limits that had been in effect for decades. Mormon men serve full-time, two-year missions, while women serve 18-month missions.
"I am not suggesting that all young men will - or should - serve at this earlier age," Monson said, adding it's an option based on individual circumstances and a determination by local church leaders.
Missionaries must be graduates of high school or its equivalent, he said.
Monson also said the church will build temples in Tucson, Ariz., and Arequipa, Peru. In Arizona, three temples already are in operation and two others - in Phoenix and Gilbert - were under construction. The state is home to about 400,000 church members.
The temple in Arequipa will be the third in Peru, which has more than 500,000 church members. Members in Arequipa, Peru's second most populous city, currently attend temple services about 500 miles away in Lima.
The church, with its more than 14.1 million members, has 139 operating temples worldwide and has another 29 planned or under construction.
At a later news conference, Jeffrey R. Holland, of the Quorum of the Twelve Apostles, said church leaders were unsure how many more missionaries would serve due to the lowered age requirements but they expect a boost.
He also said leaders considered extending the length of missions for women to two years, but decided to see how the lower age goes first before possibly taking that step, The Salt Lake Tribune reported.
Tens of thousands of Mormon faithful were gathering in Salt Lake City through Sunday for the general conference.


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Difference between revisions of "2014 Group Project 1"
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Revision as of 18:08, 8 October 2014
|2014 Student Projects
|2014 Student Projects: Group 1 | Group 2 | Group 3 | Group 4 | Group 5 | Group 6 | Group 7 | Group 8
|The Group assessment for 2014 will be an online project on Fetal Development of a specific System.
This page is an undergraduate science embryology student and may contain inaccuracies in either description or acknowledgements.
- 1 Respiratory
- 2 Lung Development Stages
- 2.1 References
- 2.2 Current Research, Models and Findings
- 2.3 Historic findings
- 2.4 Abnormalities
- 2.4.1 Newborn Respiratory Distress Syndrome (Hyaline Membrane Disease)
- 2.4.2 Meconium Aspiration Syndrome (MAS)
- 2.4.3 Bronchopulmonary Dysplasia
- 2.4.4 Cystic Fibrosis
- 2.4.5 Laryngeal Atresia
- 2.4.6 Congenital High Airway Obstruction Syndrome (CHAOS)
- 2.4.7 Congenital Laryngeal Webs
- 2.4.8 Congenital Pulmonary Airway Malformation
- 2.4.9 Azygos Lobe
- 2.4.10 References
- 2.4.11 Laryngo-tracheo-oesophageal clefts
The respiratory system allows the body to take in oxygen and exhale carbon dioxide. The respiratory system is formed by the endoderm. The splanchnic mesoderm develops into connective tissue, cartilage and muscle of the respiratory system. The respiratory system moves the air in from the nose to the pharynx, larynx, trachea, bronchus and alveoli, which is where gas exchange occurs. During the embryonic and fetal stage the respiratory system is developing. The embryonic stage is the first 1-8 weeks and anything after that till about week 37 or birth is the fetal stage. However the respiratory system does not carry out gas exchange until birth. Whilst the embryo or fetus are in the mother, gas exchange occurs through the placenta. Once born the lungs of the new born are drained and fill up with air automatically. The lungs do not inflate completely till about 2 weeks of the new born. The surfactant in each alveoli helps keep the lungs open and prevents it from collapsing. The respiratory tract is divided into two main parts; the conducting zone and the respiratory zone.
Conducting Zone
The conducting zone is made up nose to bronchioles and its function is to filter, warm, and moisten air and conduct it into the lung. The conducting zone includes the nose, pharynx, larynx, trachea, bronchi and bronchioles. Nares are the opening into the nose and is where nasal cavity is lined with cilia, mucous membrane and consists of blood filled capillaries. The oral cavity id formed by the stomodeum, which is the depression in the embryo located between the brain and the pericardium. This depression is known as the precursor of the mouth and the anterior portion of the pituitary gland. The stomodeum is ectoderm lined depression, separates the primitive pharynx by the buccopharyngeal (oropharyngeal) membrane. The membrane later breaks down and stomodeum opens into the pharynx forms the vestibule of oral cavity. The larynx is developed from endoderm of laryngotracheal tube. The splanchnic mesoderm is important for the development of connective tissue and muscle. The bronchi is formed in week 4 and the lung buds develop and further divide each into more divisions. The left 2 and the right 3. These bronchioles will continue to divide until 17 subdivisions. After the baby is born the the bronchiole tree further divides 6 more divisions.
Respiratory Zone
The respiratory zone includes the terminal bronchioles, alveolar ducts and alveoli. The respiratory zone is where the oxygen and carbon dioxide exchange with the blood. The alveolar ducts and the bronchioles cause the 10% of gas exchange. The rest of the 90% is due to the alveoli. Terminal bronchioles are the passageway for air to pass through from the bronchioles to the alveoli (air sacs) of the lungs. The alveolar ducts allows the oxygen and the carbon dioxide to move between the lungs and bloodstream. The alveoli is where the carbon dioxide and the oxygen exchange.
Lung Development Stages
|Embryonic (week 4-5)
|Lung buds would have formed and lung lobes and the bronchopulmonary segments. The stem diverticulum will have differentiated into trachea and larynx.
|Pseudoglandular (week 6-16)
|The events that occur in this stage include the formation of extensive airway branching of about 14 or more generations of branching resulting in terminal bronchioles. The conducting epithelium tubes are formed and are surrounded by thick mesenchyme. At 2 months all of the segmental bronchi would have formed. The distal structures at this stage are lined with cuboidal epithelium.
|Canalicular (week 16 to 25)
|The terminal bronchioles divide into two or more respiratory bronchioles and an increase in capillaries that get in contact with the cuboidal epithelium. The beginning of alveolar epithelium development is now underway and the lung morphology has drastic changes occur. the respiratory vasculature is now being developed. the differentiation of the pulmonary epithelium results in the formation of air-blood tissue barrier. This differentiation of cells transforms into specialised cell types known as ciliated, secretory,alveolar cells type 1 and 2. It is notable that the differentiation of the future conducting airways of the lung from the future gas exchange region is noticeable.
|Saccular (week 24- 40)
|The terminal sacs along with the alveolar sacs and ducts have now formed. The saccules both widen and lengthen the air sac. There is a dramatic expansion in future gas exchange region in this stage. Fibroblasts also differentiate, they can now produce extra matrix, collagen and elastin. The vascular tree is also seen to grow in length and diameter. The terminal sacs will continue to develop until well into childhood.
|Alveolar (week 36- 8 years of age)
|The secondary septation occurs and a significant increase in the number and size of capillaries and alveolar. postnatally from 1-3 years the alveoli will continue to form and in asa result increasing the surface area for gas exchange.
Anatomy and development of oral cavity and pharynx
<pubmed>22844507</pubmed> <pubmed>5323506</pubmed>
Current Research, Models and Findings
Current Models
Current Reseach and Findings
Current research looks at the molecular processes that underpin two important developmental stages of the lung. The lung can anatomically be divided into two parts; an upper respiratory tract and a lower respiratory tract [1].However, physiologically, the organ can be divided into two parts 2 that occur subsequently:
- The Conducting system- consisting of all the tubular structures such as the larynx, trachea, and bronchi.
- The Functional unit- An alveolus. Alveoli (Plural). Specialised epithelial cell, the at which gas exchange of carbon dioxide and oxygen takes.
Much research has been undertaken to understand how each of these processes occurs individually. However, a study conducted last year shows evidence that during later stages of fetal development, when the expands, these two important processes involve co-ordinated cellular interactions and take place at a precise time within development and at a specific location [2].
By week 8, the respiratory system of the fetus is well underway and the development of the lung is at the pseudoglandular stage (see above for more information for the properties of this stage). The three germ layers (ectoderm, mesoderm and endoderm) have each contributed to the development of the lung and their involvement is crucial for regulating a cascade of sequential number of events including bronchial branching (see 1. The conducting system) and alveolar differentiation (see section 2. Functional Unit).
1. The Conducting system - The respiratory network
Branching morphogenesis is the growth and branching formation to build a treelike tubular network ending with specialized air bubbles (alveoli) as sites for gas exchange[2].
• In 2013, a review study conceptualised how we now currently understand the model of branching morphogenesis. There are currently three geometrically models proposed for the way in which the primary bronchial buds branch:
- Domain branching
- Planar bifurcation
- Orthogonal bifurcation
- Trifucation --add reference from intro
• Another recent study conducted in 2013[2], suggests that there is a correlative interaction between the lung epithelium and the surrounding plural mesenchyme. The mesenchyme secretes fibroblast growth factor (FGF10) secreted by the mesenchyme, which in turn activates its membrane receptor co-worker (FGFR2). The epithelium, sequentially then generates a small amount of GTPase (KRAS). Both these contributions are involved in a cascade of signaling pathways essential for normal branching morphogenesis of the lung.
2. The Functional Unit
At the end of the conducting system or at the end of the tertiary bronchial, lie the sites of gas exchange- alveolar air sacs. This process of differentiation from building on to the branched duct to specialised alveolar cells is a process named alveolar differentiation.
• There are two alveolar cell types[2]:
- Type I alveolar cells are flat and cover more than 90% of the alveolar surface, across which gases diffuse. The exchange of carbon dioxide, CO2 for 02. However, whilst the fetus is still growing inside the uterus this gas exchange does not occur. The first breath is just after delivery and hence the first time in which the alveolar serve their purpose is after birth.
- Type II alveolar cells are cuboidal and play and crucial role in the respiratory development of the fetus post-natally. They synthesize pulmonary surfactants, lipoprotein complexes that hydrate the alveolar surface and prevent alveolar collapsing by reducing surface tension.
- ↑ <pubmed>24058167</pubmed>
[1] <pubmed>22844507</pubmed> <pubmed>20692626</pubmed> <pubmed>22359491</pubmed>
Historic findings
Historical knowledge predating modern imaging techniques has most often been confirmed by contemporary studies that provided evidence for the claims of early respiratory development. At times, theories put forward for fetal respiratory development were enhanced with further detail, whereas elsewhere paradigms were shifted and challenged due to the availability of proof otherwise [3]. The understanding of the development of the upper and lower respiratory system during the fetal period from week 8 onwards, as well as their respective functions, have been around since the 19th Century [4].
- 1929: The earliest recorded observation regarding the necessary presence of something in the lungs was proposed by Swiss physiologist Kurt von Neergaard through experiments performed observing the surface tension within the alveoli [5]. Unfortunately these findings were largely disregarded until decades later when they resurfaced in importance.
- 1954: Research on warfare chemicals by Pattle, Radford and Clements led to the understanding of the physical properties of surfactant [6].
- 1959: The final link to provide a sound understanding of the importance of surfactant was by Mary Ellen Avery and Jere Mead. They had published a study showing that premature neonates were dying from respiratory distress syndrome (RDS) due to insufficient pulmonary surfactant [7]. The lung extracts obtained from hyaline membranes of babies with RDS showed this deficiency.
- 1963: Adams et al observed that fetal lung surfactant possessed particular characteristics that indicated it came to be present within the lung due to an active secretory process, which became foundational in linking the role of Type II pneumocytes with the secretion of surfactant. [8]
- 1994: Discovery made regarding the reversed process of clearing pulmonary fluid from the lung rather than secreting it as surfactant by the baby upon birth, was conducted by Hummer et al. The experiment was performed in mice and indicated towards neonates who die as a result of failure to clear liquid from their lungs in the first 2 days of birth. [8]
Alveoli formation
- An Italian scientist by the name of Marcello Malpighi (1628-1694) contributed greatly to medicine, particularly the understanding of anatomy as he was a pioneer biologist to utilise newly invented microscopes to closely observe. For this reason, he is most recognised as the discoverer of the pulmonary capillaries and alveoli. [9]
- Studies of the early 1900s specifically in regards to the cellular content of alveolar wall linings indicated that there was a high presence of nucleated cells in the fetus. This led to a greater understanding in the functionality of the alveoli when just at the fetal stage. [10]
- J. Ernest Frazer conducted studies to research lung development along with improving the understanding of general human anatomy during his time. [11]
- The differentiation of surrounding mesenchyme into alveoli was contained within a membrane known as the pleural cavity that was separated off the peritoneal and pericardial cavities --> When was this distinction discovered..
- ↑ <pubmed>24058167</pubmed>
- ↑ https://php.med.unsw.edu.au/embryology/index.php?title=File:Cryptorchidism.jpg.
- ↑ <pubmed>23431607</pubmed>
- ↑ <pubmed>16601307</pubmed>
- ↑ <pubmed>18446178</pubmed>
- ↑ <pubmed>15985753</pubmed>
- ↑ <pubmed>14509914</pubmed>
- ↑ 8.0 8.1 <pubmed>24160653</pubmed>
- ↑ <pubmed>23377345</pubmed>
- ↑ <pubmed>19972530</pubmed>
- ↑ Keith, A. (1902) Human Embryology and Morphology. London: Edward Arnold.
1. Developmental Biology, 6th edition By Scott F Gilbert. Swarthmore College Sunderland (MA): Sinauer Associates; 2000. ISBN-10: 0-87893-243-7
- Links: | Developmental Biology
Comparative embryology with detail on historical understandings of early respiratory development observed in various species. Accessible through PubMed.
2. Human Embryology and Morphology, 1902 By Arthur Keith London: Edward Arnold.
Historical images of past understandings on respiratory development
3. YouTube Video explaining early respiratory development
4. Lavoisier
Newborn Respiratory Distress Syndrome (Hyaline Membrane Disease)
Newborn Respiratory Distress Syndrome (NRDS), also known as Hyaline Membrane Disease (HMD) is characterised by the lack of or inability to synthesise surfactant in the premature lung of neonates.
The incidence of NRDS occurs in babies suffering form immature lung development, usually from premature birth with increased severity and incidence in correlation to decreased gestational age [1]. Preterm births do not allow for full lung maturation of the preterm infant due to process in which the respiratory system forms (from upper respiratory tree to lower). Type II Pneumocytes secrete surfactant into the alveoli, reducing surface tension and thus preventing the collapse of the alveolus – they are the last respiratory cells to differentiate. Preterm infants usually lack Type II Pneumocytes in their lung tissue causing the instability of their alveoli, oedema from immature alveolar capillaries and hyaline membrane formation[2].
NRDS mostly occurs in preterm neonates but can occur in post-term and term babies for a variety of reasons including:[3]
- Intrauterine Asphyxia – commonly caused by wrapping umbilical cord around the neck of the neonate, impairing development[1]
- Maternal diabetes – high levels of insulin can delay surfactant synthesis[4]
- Multiple pregnancy (twins, triplets etc) – associated with high rates of preterm births and resulting lung immaturity [4]
- Rapid labour, fetal distress, placenta previa, preeclampsia, placental abruption – that impair lung maturation in final stages of pregnancy [4]
- Preterm Caesarean delivery – not allowing for lung maturation[5]
- Genetic abnormalities that impair surfactant synthesis (ABCA3)[6]
- Meconium Aspiration Syndrome (MAS) - causes damage to the lower respiratory tract after aspiration of Meconium in amniotic fluid[7].
Meconium Aspiration Syndrome (MAS)
Meconium Aspiration Syndrome (MAS) affects newborn infants in response to some form of fetal stress during the third trimester and/or parturition, often due to: acute hypoxia, intrauterine hypoxia (often caused by the wrapping of the umbilical cord around the neck of the baby) and other physiological maturational events. [7][8].
Stress on the baby before or during labor can cause relaxation of the anal sphincter leading to expulsion of Meconium by the foetus into the surrounding amniotic fluid which can then be aspirated by the fetus, damaging the upper respiratory tract and possibly the lower respiratory tract. [9].
Problems associated with Meconium aspiration include[7]:
- Pulmonary gas exchange deficiency -caused by damage to the lower respiratory tract epithelium.
- Pneumitis and pneumonia - due to chemical damage and irritation from Meconium interaction with the airways.
- Blockage of the airways
Bronchopulmonary Dysplasia
Bronchopulmonary dysplasia (BPD) is a common complication in the treatment of Newborn Respiratory Distress Syndrome (NRDS) in infants born more than 10 weeks premature and of low weight. Efforts to treat breathing difficulties associated with NRDS can cause damage to the vulnerable lungs of the infant[10]. The complications can occur from a number of reasons following treatment[11]:
- Oxygen therapy causing inflammation to the lung epithelium due to the higher amounts of oxygen administered
- Used in more critical cases because of the complications associated with this form of treatment, air pressure from ventilation machines can further damage the premature lungs.
- There is some growing evidence that genetics may play a role in the predisposition of BPD [12].
- Infections from treatments involving ventilation can also occur leading to inflammation of the upper respiratory tract.
Cystic Fibrosis
Cystic fibrosis (CF) is caused by a mutations of the cystic fibrosis transmembrane conductance regulator (CFTR)[13]. The defect associated with this mutation results in the excretory glands of the body producing a thick sticky mucus as well as salty sweat. The disease affects several organs in the body but mainly affects the respiratory system allowing impairing the response to bacterial infection and causing inflammation in the airways[14][15]. This aberrant production of mucus can lead to the mucus stasis in the pulmonary epithelium, airway plugging, inflammation and chronic bacterial infection causing the decrease in lung function.
Laryngeal Atresia
Laryngeal Atresia (LA) is incredibly rare and occurs as a failure of the laryngo-tracheal tube to recanalise, obstructing the upper respiratory tract leading to a larynx with no lumen[16]. This can cause Congenital High Airway Obstruction Syndrome (CHAOS) [17]. Genetic abnormalities have been identified as having an association with AL [18].
Congenital High Airway Obstruction Syndrome (CHAOS)
Congenital High Airway Obstruction Syndrome (CHAOS) is extremely rare and is the result of an obstruction to the fetal airways. This obstruction can be caused by atresia of the larynx or trachea, laryngeal cysts, laryngeal webs and subglottic stenosis[19]. Reviews have revealed that most cases are fatal[20] but ex-utero partum treatments (EXIT) have been successful in treating this condition[21]
Congenital Laryngeal Webs
Similarly to Laryngeal Atresia, Congenial Laryngeal Webs (CLW) are caused by failure of the laryngo-tracheal tube to recanalise, usually at the level of the vocal chords. The lumen and vocal chords of the larynx is usually developed after the epithelium is reabsorbed but in the case of CLW, this reabsorption is incomplete leaving 'web-like' formations in the larynx that obstruct normal development and airflow. [22]
Congenital Pulmonary Airway Malformation
Congenital Pulmonary Airway Malformation (CPAM) occurs at varying degrees and is defined by its location in and the level of differentiation of alveoli[23]. In the cases of type I and II, CPAM involves the presence of cysts affecting the terminal bronchioles and lung parenchyma. CPAM is thought to be caused by an abnormal development of the lung bud in week 4-5 of development and leads to the malformation of the pulmonary airways via the formation of lung abscesses, pulmonary infections and the sequestration of areas of the lung[24]. Recent reviews have also suggest that thyroid transcription factor 1 (TTF1) may have a role in CPAM as it is involved in the differentiation of lung epithelium and overall pulmonary development. [25].
- Type I - is defined by large multilocular cysts occurring in one of the pulmonary lobes
- Type II – define by the presence of smaller more uniform cysts.
- Type III – is defined by larger lesions that affect the lung parenchyma of en entire lobe.
Azygos Lobe
Azygos lobe (also known as Adam's lobe) occurs due to the aberrant formation of the azygos vein as it veers from its normal course over the apex of the right lung to penetrate the upper lobe. An accessory fissure is formed in the upper lobe and the pulmonary parenchyma located in the medial portion is identified as the Azygos Lobe. There have been three observed types of azygos lobe that are relatively harmless and present little clinical significance (except during surgery due to variations in the course of the phrenic nerve): [26].
- Upper Azygos Lobe
- Lower Azygos Lobe
- the Lobe of the Azygos Vein
- ↑ 1.0 1.1 <pubmed>20468585</pubmed>
- ↑ <pubmed>6071188</pubmed>
- ↑ <pubmed>10829971</pubmed>
- ↑ 4.0 4.1 4.2 <pubmed>20848797</pubmed> Cite error: Invalid
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- ↑ <pubmed>14629318</pubmed>
- ↑ <pubmed>15044640</pubmed>
- ↑ 7.0 7.1 7.2 <pubmed>10612363</pubmed>
- ↑ <pubmed>16651329</pubmed>
- ↑ <pubmed>19399004</pubmed>
- ↑ <pubmed>22785261</pubmed>
- ↑ <pubmed>19712501</pubmed>
- ↑ <pubmed>25031518</pubmed>
- ↑ <pubmed>24685676</pubmed>
- ↑ <pubmed>16928707</pubmed>
- ↑ <pubmed>22763554</pubmed>
- ↑ <pubmed>14325849</pubmed>
- ↑ <pubmed>2342705</pubmed>
- ↑ <pubmed>3566610</pubmed>
- ↑ <pubmed>22167132</pubmed>
- ↑ <pubmed>12778398</pubmed>
- ↑ <pubmed>9802816</pubmed>
- ↑ <pubmed>16798587</pubmed>
- ↑ <pubmed>24672262</pubmed>
- ↑ <pubmed>21355683</pubmed>
- ↑ <pubmed>21762550</pubmed>
- ↑ <pubmed>16333920</pubmed>
<pubmed>22151899</pubmed> <pubmed>22214468</pubmed> <pubmed>12547712</pubmed>
Laryngo-tracheo-oesophageal clefts
- Bronchopulmonary Dysplasia.
- Surfactant Metabolism Dysfunction and Childhood Interstitial Lung Disease (chILD).
- Evaluation of fetal vocal cords to select candidates for successful fetoscopic treatment of congenital high airway obstruction syndrome: preliminary case series.
- The epidemiology of meconium aspiration syndrome: incidence, risk factors, therapies, and outcome.
- Antenatal infection/inflammation and postnatal lung maturation and injury.


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Indica et Buddhica offer Resources for Indologists and Buddhologists. This is an overview of the resources provided, as mentioned on the site itself:
1. Indica et Buddhica: http://indica-et-buddhica.org/ — provides resources for Indologists and Buddhologists; as the top level domain, this is the public portal or entrance to the site.
2. Lexica: Sanskrit, Tibetan and English: http://lexica.indica-et-buddhica.org/ — an interface giving access to definitions from two Sanskrit to Tibetan word lists and Monier-Williams Sanskrit-English Dictionary; remote client access is available using the Dictionary Server Protocol (DICT).
3. Philologica: Machine Readable Texts: http://philologica.indica-et-buddhica.org/ — provides machine readable texts and digital instruments for philological research; a full text search, retrieval, and analysis system is available for a collection of Sanskrit texts, including the Mahabharata and Ramayana.
4. Scholia: Indological and Buddhological Scholarship: http://scholia.indica-et-buddhica.org/ — enables researchers to catalogue, store and retrieve bibliographical materials, including data on articles, books, images, theses, software, working papers and so on; records can be viewed and downloaded in various formats including BibTeX, EndNote, RIS, and Dublin Core.
5. Catalogus Bibliothecarum: A Catalogue of Collections: http://catalogus.indica-et-buddhica.org/ — a virtual union catalogue providing central access to over 130 library servers with significant Indological and Buddhological collections; enables users to conveniently locate and obtain records with a single interface; records can be viewed and downloaded in various bibliographical formats.
6. Repositorium: A Storage Place for Materials: http://repositorium.indica-et-buddhica.org/ — a digital archive designed to capture, store, index, preserve, and distribute materials pertinent to Indology and Buddhology; holds materials for the study of Nagarjuna and Santideva, a manuscript catalogue, and Sanskrit and Tibetan lexica.
7. Tabulae: Tables of Contents for Indology and Buddhology: http://tabulae.indica-et-buddhica.org/ — increases the availability and usefulness of online journals containing Indological and Buddhological material; links, aggregated feeds and bibliographical data makes this material easier to find, access and use.


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Although the number of young people applying for a work permit and temporary lawful status under the Deferred Action for Childhood Arrivals (DACA) program has fallen in recent weeks, one thing hasn't changed: the number of cases being approved remains (as it has been for several months) around 96%. It's almost uncanny. You can check out U.S. Citizenship and Immigration Services' (USCIS's) latest figures here.
And for more information on the DACA program, check out Nolo's series of articles.


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"The energy efficiency of the Fujitsu hardware is great and there has been a massive difference in performance in terms of latency and Input/Output. Importantly, we will also be able to incorporate GPUs to handle the demands of processor-intensive applications such as Adobe Creative Suite, Corel Draw, Solid Works and XYZ 3D Printing software"
James Henderson, Network Manager, Kennet School
Kennet School is an academy secondary school in Thatcham, Berkshire. In 2011, Kennet School was the highest achieving state school in West Berkshire according to contextual value added results and third-highest using five good GCSEs. The school has an annual income of just over £8.9 million and spends roughly £5,000 per student per year. The school opened on 11 September 1957 as a secondary modern, before converting into a comprehensive in 1971 and finally changing to an academy on 1 April 2011. The school has over 2,000 pupils with 121 teachers and 78 non-teaching staff.
Kennet School wanted to virtualise its desktop infrastructure and needed a reliable and flexible server platform to support the project.
Following an evaluation process, the school decided that Fujitsu offered the best price/performance ratio as well as being the only vendor to enable GPU integration.
Read the full Kennet School case study (732 KB/A4, 2 pages)
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Sake School: Rick Smith and Hiroko Furukawa of Sakaya in NYC
In December 2007, Rick Smith and Hiroko Furukawa opened what is to this day the East Coast's only store dedicated entirely to sake. But they weren't always sake's biggest fans.
Rick, who held a ten year tenure as Associate Publisher of Food & Wine, had his first sake epiphany in late 2000, during a company dinner at Jewel Bako. After initially resisting proprietor Jack Lamb's suggestion to pair his meal with premium sakes, Rick gave in and his eyes were opened to a world completely different from the "jet fuel" sake he'd tried before.
Although Hiroko was born and raised in Japan, she didn't fall in love with premium sake until she went to New York's temple of sake, Sakagura. Hiroko and Rick met shortly thereafter, and their shared passion for premium sake eventually led them to open Sakaya.
I recently had the opportunity to chat with Rick and Hiroko about their reasons for getting into this business, customer observations, and much more.
What made you decide to open a sake store?
We often found ourselves trekking to New Jersey to buy sake at Mitsuwa, and visiting the many wine stores around the city with interesting sake selections, but we still felt like we weren't getting the true variety and selection we desired. We were further inspired by visiting True Sake in Northern California (the first sake store in the US) and talking with Beau Timken, proprietor and sake aficionado. We felt that if San Francisco, with one tenth of NYC's population, could sustain a sake store, then we definitely had a shot as well.
Do you feel that there are any categories or price ranges missing in what's available in NY?
We're fortunate to have an excellent variety of sakes in many price ranges in NY. We do sometimes feel that it's tough to turn people on to sake due to the price gap between bulk sake and premium sake; however, although we make an effort to offer sake in a more approachable price range, we consistently see that our best sellers are sakes in the higher end categories.
What is your advice for a beginner who wants to learn about sake?
Try lots of different sake and take notes on each one. Writing down your thoughts requires concentration on the sake's characteristics, which tends to ingrain the sake in your memory. As you build a body of experience, familiarity with styles, rice, and yeasts will begin to take form in your mind. We also recommend reading John Gauntner's The Sake Handbook as a foundation or framework to use as the basis for sake exploration. And check out our website!
Do you feel that your customers' level of familiarity with sake has grown over the years?
Absolutely. Our longtime customers have identified the styles they like after trying a bunch over time, and that greatly increases their confidence in selecting sakes. Also, lately people are walking in the door, pulling out their phones and showing us photos of sake they've had in restaurants, or have typed the names of sakes into their Blackberrys. This attention is a great sign that people are starting to take sake more seriously.
What style of sake do you recommend to new sake drinkers?
We try to match the style to the drinker's taste preferences, so for us, there really isn't one all-encompassing answer to this question. Since everyone has different taste, there isn't really a "one-size fits all" sake.
What are some frustrations that you've had about the sake market in the US?
Despite the increasing enthusiasm of sake drinkers, sake still isn't an 'everyday drink' for most people. We see people who probably go through a case of wine every week in their household, who will only ever pick up a bottle of sake for special occasions.
People also seem limited in their expectations of sake's versatility. So many people still think that sake can only be enjoyed with sushi. At Sakaya we make a big effort in our shelf talkers to recommend food pairings outside of just sushi—anything from cheeses to Bolognese sauces.
How do you see the sake business changing in the next 10 years or so?
We think there is great potential for growth. Premium sake in the U.S. is at a similar stage to where wine was about 20 years ago—back then, people knew very little about wine aside from the fact that there was red and white. As premium wines became more widely available, drinkers became interested in the differences between them and sought more information about where they came from. We see a similar learning curve for premium sake.
What have been some of the challenges and surprises for you during your time owning Sakaya?
Since neither of us had any business start-up or retail experience, everything was a challenge at first (and continues to be)! It has been round-the-clock and all-consuming and we've learned so much along the way. Fortunately we've had some wonderful people who shared the benefit of their experience with us. We didn't know what to expect but relied on our instincts and thank goodness, that seems to have kept us growing steadily since day one. Surprises? I would say that we're pleasantly surprised at the level of enthusiasm and degree to which people have embraced the shop. We're also tremendously happy about the excitement that the sake brewers have shown in their support of SAKAYA. Their visits to our shop, hosting us at their breweries, and year round communication with us are essential to our ability to provide our customers with a greater depth of understanding of what goes into producing the sake that we carry.
What is the most adventurous sake and food pairing that you've done lately? Kagatobi Junmai Ginjo with dark chocolate. This sake has a great nuttiness and acidity, and the rich texture that really matches the intensity and nuttiness of dark chocolate.
What are some of the most popular styles of sake at Sakaya? Definitely bold, intense, fruity styles of sakes like namazake (unpasteurized sakes) and genshu (undiluted, higher alcohol sakes). Probably second after that would be soft, elegant, very easy drinking sakes.
Are there any programs you offer at the store to give people an ongoing sake education?
We offer America's first "Sake of the Month" tasting club. We focus on a different sake theme every month, and offer six sakes in that genre to members of our mailing list. Each focus is a basic principle that we are working on educating people on, such as sake to match with grilled dishes for the summer, comparative tastings of different types of sake rice, East v. West, etc.
Along with the sakes we include information about each one, including background on the yeast, rice, SMV, and alcohol, along with serving and pairing suggestions. It's very flexible: people can opt in each month, and there is an option to try 2, 4, or 6 different sakes. We try to keep each pair of sake under $80 total so that it stays fairly affordable. We also deliver—so it's a great way to get a feel of what we're about if you're not close enough to stop by in person!
324 East 9th Street, NY 10003 (map) 212-505-7253; sakayanyc.com
All products linked here have been independently selected by our editors. We may earn a commission on purchases, as described in our affiliate policy.


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When you visit our Cape Cod Bed and Breakfast, we will do our very best to provide you with information we hope will be helpful in your exploration of the Cape. If you have never visited the Cape (as we locals call it), it may be helpful for you to learn about the various villages and towns that make up this lovely area that attracts so many visitors each year. There is so much to see and do here and we hope this over-view and website links will help you in planning your Cape Cod visit.
Cape Cod is made up of three distinctive areas; Upper Cape, Mid Cape, and Lower Cape. This blog will feature an overview of the villages and towns of Upper Cape Cod.
Sandwich is where Cape Cod Begins. It is located just an hour from both Boston, Massachusetts and Providence, Rhode Island, where major airports are located. Settled in 1637 and incorporated in 1639, Sandwich holds the distinction of being the oldest town on the Cape. As you travel the winding back roads and pathways of old Sandwich Village, you are strolling through living history surrounded by distinctive boutiques, restaurants, and unique lodging choices. Located in the village are many working museums, art galleries, and a multitude of opportunities for exploration, recreation, and relaxation. Sandwich has it all.
Spend time visiting our many museums, bike the Cape Cod Canal Bike Path, stroll through the 100 + acres of beautiful Heritage Museums & Gardens, take a jam making class at the Green Briar Nature Center Jam Kitchen, walk on the beach, and by all means enjoy some wonderful local cuisine. See the "What's Inn Our Sandwich" page on our website to read about some of the reasons people from all over the world come to visit.
Bourne is located adjacent to Sandwich. The town of Bourne is made up of nine villages, one of which is Gray Gables. During the 1890's, this village was home to the first summer White House where President Grover Cleveland spent vacations. The village of Buzzards Bay is a commercial center with views of Buttermilk Bay. The Cape Cod Canal Bike Path runs through Bourne and the Aptucxet Trading Post is located there. Bourne is also home to the Massachusetts Maritime Academy, the country's oldest co-ed maritime college.
South of Bourne is the town of Falmouth, the second largest town on Cape Cod. Falmouth has 14 harbors and numerous saltwater inlets. At Falmouth Harbor you can catch the Island Queen, a quaint pedestrian ferry, to the village of Oak Bluffs on Martha's Vineyard. The author of "America the Beautiful," Katherine Lee Bates, was born and raised here. There is a beautiful downtown area with a Town Green that was once a common cattle-grazing area.
Falmouth is home to historic Highfield Hall, which was built in 1878. The 20,000 square-foot restored Victorian mansion is open to the public April through October. The former stable for Highfield Hall now houses the Falmouth Theatre Guild, where Broadway musicals are produced fall through spring. In the summer months, the theatre is home to the renowned College Light Opera Company. Visit their website for a complete listing of performances.
Located in North Falmouth is Old Silver Beach. This white sandy beach is a great place for sunbathing and watching the sun set. Falmouth is also home to the Shining Sea Bike Path, which is a lovely 8-mile ride along the coast with a beautiful view of Nobska Light.
A part of Falmouth is the Village of Woods Hole. This charming village is home to three world-class scientific institutions: Woods Hole Oceanographic Institute, the Marine Biological Laboratory, and the National Marine Fisheries Service. The beautiful Nobska Lighthouse is located here and is open to the public with limited visiting times. Woods Hole has many charming restaurants including Fish Mongers and a bakery that is a personal favorite of this innkeeper, Pie In The Sky. The Steamship Authority ferries to Martha's Vineyard depart from Woods Hole.
Mashpee, the only Cape Cod town with a Native American name, was home to one of the Wampanoag tribes (the Massipees) long before European settlers arrived. The Indian Meeting House located on Route 28 in Mashpee is still used by the tribe for meetings, events, and religious services. Mashpee is home to Mashpee Commons, one of the most upscale village-style shopping centers on Cape Cod. The Commons has become a community hub, hosting events and concerts throughout the year.
We hope to welcome you to our Inn very soon. Sandwich is a great place to stay and explore the rest of Cape Cod and the islands of Nantucket and Martha's Vineyard. See the "Specials" page of our website for packages and specials.
Jan Preus, the Innkeeper, chef, and artist in residence at the 1750 Inn at Sandwich Center, Sandwich, Cape Cod, Massachusetts
Wednesday, March 9, 2011
Cape Cod Vacation - The Upper Cape
Posted by 1750 Inn at Sandwich Center at 7:48 PM
Labels: About Cape Cod
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An up-and-coming musician who goes by the name of Wolfgang Amadeus Mozart has the best-selling CD of the year. Not Kanye. Not Drake. Not even Salieri. Mozart.
So how did it some guy that no one's ever heard of sold more CDs than Drake? And how come no one cares for Salieri anymore?
Turns out, Decca released a monster collection in commemoration of the 225th anniversary of Mozart's death, which sold 1.25 million copies in its first five weeks. That's right, while Salieri was becoming "the patron saint of mediocrity," Mozart was going platinum.
Mozart 225: The New Complete Edition contains every piece of music Mozart ever wrote, reports Billboard. That's 240 hours worth of music — not that anyone's trying to make a collection for Salieri, who just wanted to sing to God, but God made him mute.
Still, this man, this creature, who still outsells Salieri, had a trick up his sleeve. The box set contains 200 CDs, so actually 6,250 box sets were sold. So while it's a lot for someone no one has ever heard of, Drake still beat him in streaming. According to The Verge, Drake, who also outsells Salieri was streamed 4.7 billion times.
And yet, Salieri goes unnoticed, absolving mediocrities everywhere.
Side Note: Milos Forman's Academy Award-winning biopic of Mozart, Amadeus is streaming on Netflix. If you didn't watch twice a week in band during high school, now's your chance to check it out.


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New York state's 64-campus university system is undertaking a major virtual expansion, adding new online degree programs and enhancing academic and technical support for students taking classes via computer.
In what it's calling "Open SUNY," the State University of New York goes live Tuesday with eight new online degree programs at six campuses and plans to add more in September. SUNY currently offers more than 12,000 courses and 150 degree programs online.
Students will be able to complete degrees online or through a combination of virtual and brick-and-mortar classes.
Chancellor Nancy Zimpher announced plans for the expansion a year ago. The goal is to enroll 100,000 new online students over the next five years.
"Our reach is already pretty big — 465,000 students is huge," Zimpher said in a telephone interview. But "It's important to look at underserved and undereducated citizens."
SUNY continues to court the traditional college-age student to live and study at its network of campuses, but it also wants to attract a new class of online learners from among the 6.9 million adults in the state who completed high school but lack college degrees. SUNY hopes the online initiative becomes its signature.
The new offerings will be aligned toward jobs in high demand. They include a clinical laboratory technologies degree program at SUNY Broome, an electrical engineering degree program from Stony Brook and an informations systems program through Empire State College.
At the center of Open SUNY is a website — described by the chancellor as "an open door" — that will guide students through course selection, financial aid, internships and other practicalities of study.
"They will see how to subscribe, they will be assured they will be supported with online mentoring," Zimpher said. "We'll help them with their finances, we'll make sure they're taking the courses in the right sequence, and we will give them access to a support base."
The support will be especially important for students who have been frustrated by college in the past by getting shut out of courses or unable to connect with an adviser, she said.
The ambitious goal has some university faculty worried about a potential strain on technology or ballooning section sizes, said Fred Kowal, president of United University Professions. Professors also want assurances they will remain in control of their classes.
"We certainly support the use of online education as a methodology," he said. "We want to make sure it's done well and enhances the reputation of the university."
The initiative also includes support for faculty wading into online learning and for those with experience.