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For about 15 seconds, Toby Imada had James Krause figured out.
Imada landed a right hand right out of the gate, then moved in. But Krause survived the momentary early offense from his opponent, then cruised past him for a unanimous decision in the main event of Resurrection Fighting Alliance 6.
RFA 6 took place at Scottish Rite Temple in Kansas City, Mo. Seven of the eight pro fights on the card aired live on AXS TV.
Imada stood in the pocket with Krause after backing him up with his early right hand. He looked to throw some big bombs, then tried to take Krause to the canvas. Krause worked for a guillotine, but Imada twisted his way out of it and Imada looked for a standing guillotine of his own until Krause broke it off.
But after that, it was all Krause, who pumped a jab over and over and tried to work in kicks, using his range to keep Imada almost constantly on the outside.
Imada, bloodied after the first round, tried for a takedown in the second – anything to change the tempo of how things were going on the feet – but Krause was having none of it. Imada secured a brief takedown in the third, but Krause was back up without much trouble and went right back to his wheelhouse.
Though Krause never appeared to have Imada in trouble of being finished, the continued peppering of the jab, followed by crisp combinations, took Imada right out of the fight. He was left to wing haymakers hoping to stun Krause the way he appeared to surprise him out of the gate. But nothing landed of any consequence.
The fight was a rematch from Bellator 14 in April 2010, which Imada won with a second-round armbar. But Friday's bout told a very different story.
"I really don't like talking about how much I've done this and done that," Krause said. "I'll let you guys be the judge of that. I let my performances speak for themselves, but I think I earned my keep tonight."
Krause then proceeded to ask UFC matchmaker Joe Silva to call him – by giving out his phone number in his post-fight interview, live on AXS TV.
Krause (19-4) has been on a tear and now has won seven straight fights, five by stoppage. He's been hoping for a call from the UFC. He had two shots in the WEC in 2009 but was submitted by Donald Cerrone and lost a decision to Ricardo Lamas. Imada (30-17) has dropped two straight three of his past four.
In the co-main event, Eduardo Pamplona tried to turn the tables on UFC vet Brock Larson, but it was too little too late in the eyes of the judges.
Larson's strong wrestling background helped secure him an early takedown. But Pamplona got back to his feet and briefly changed the course of things. Pamplona tried to work inside leg kicks back in the standup game, but Larson dodged away from them and pushed inside to look for an uppercut.
Pamplona worked out of a brief guillotine attempt from Larson with relative ease and found himself on top with Larson on his back against the fence. Larson looked for a triangle, but Pamplona slammed his way out of it. They traded position with Larson again looking for a final takedown to end the frame, and he got one to likely secure the round.
Larson got a single-leg takedown early in the second and went to work on top. And there he would remain, grinding Pamplona down for much of the round. He again wanted the fight on the ground in the third, but Pamplona defended well early. Midway through the round, Pamplona took advantage of a tiring Larson and got the fight to the canvas himself. He started working punches and elbows with Larson on his back pressed against the fence.
Pamplona worked to pass to side control, but though he couldn't it was still an appropriate turning of the tables against the wrestler. It may have given him the round, but it wasn't enough as all three judges scored the fight 29-28 for Larson.
Larson (36-7) won for the third straight time after a stretch that saw him drop three fights in four bouts. Pamplona (15-4) lost for the second straight time after a 10-fight win streak from 2007-2011.
RFA 6 results:
- James Krause def. Toby Imada via unanimous decision (30-27, 30-27, 30-27)
- Brock Larson def. Eduardo Pamplona via unanimous decision (29-28, 29-28, 29-28)
- Kevin Croom def. Brian Davidson via TKO (strikes) – Round 1, 0:42
- Dustin Ortiz def. Aaron Ely split decision (29-28, 28-29, 29-28)
- Dakota Cochrane def. Deivison Ribeiro via TKO (strikes) – Round 3, 4:32
- Mark Dickman def. Aaron Derrow via TKO (strikes) – Round 2, 4:35
- Bobby Cooper def. Nick Compton via unanimous decision (30-27, 30-27, 30-27)
- Cody Peterson def. Tyler Stokes via submission (armbar) – Round 2, 2:06
For more on RFA 6, stay tuned to the MMA Events section of the site.
(Pictured: James Krause)


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Kate Gosselin and her adorable sextuplets were spotted posing for a family photo yesterday on the beach at Bald Head Island, North Carolina. What a perfect family picture look at the girls long gorgeous hair.
Beach Baby's
Posted by Alisa on Saturday, June 6, 2009 / Comments: (0)
Ryan Phillippe helps coach his son Deacon at his baseball game. Also in attendance was girlfriend Abbie Cornish and daughter Ava, Ava looks so much like her mom Reese Witherspoon
Happy 1st Birthday Honor Marie
OMG HONOR MARIE WARREN IS 1 it seems like yesterday she was in jessicas tummy, Jessica Alba with hubby Cash Warren and daughter Honor head off for breakfast in Santa Monica.
OMG HONOR MARIE WARREN IS 1 it seems like yesterday she was in jessicas tummy, Jessica Alba with hubby Cash Warren and daughter Honor head off for breakfast in Santa Monica.
Kate Gossling and her little Men!
Mother of 8 Kate Gosselin accompanied by security guard Steve Neild and her three youngest sons in Wilmington, North Carolina on Thursday on June 4, 2009.
What Not to Wear host Trinny Woodall and her cute little 5 year old daughter Lyla, arrive for Angelina Ballerina's Big Audition at Wimbledon New Theatre on June 5 in London
Get Harlows Look!
The Beyond ADORABLE Harlow Winter Kate Madden wears a Bellaziza Bling 1 Barrette - $9, available with clear, pink, or ruby red crystals
With just days before welcoming the birth of her daughter her second child, the hit t.v show Gossip Girl Kelly Rutherford picks up a little reading material while enjoying an evening out in Beverly Hills on Thursday.
Rapper and actor celbrity Ice Cube and his look alike son O'shea Jackson Jr.arrive at Staples Center for game one of the NBA Finals featuring the Los Angeles Lakers versus the Orlando Magic in Los Angeles on June 4

subset: commoncrawl


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Edited by: Keedah
Fashion Week is finally upon us which means we'll be hyped up on Diet Pepsi or coffee (or both), running on mininal sleep, and bustling from event to event so we can bring you the latest happenings in the fashion industry. And the blizzard that just hit the New York area isnt making it any easier, but alas we make sacrifices for the sake of fashion. Links this week will give you insight on what trends to expect in the next few months. And as always, if you want to join The Glamarazzi you can find the info here.
- Obsession isn't Just a Perfume discovers for the first time in fashion history the fanny pack is cool thanks to an extreme makeover by Kinies. Fanny Pack Fabulous?!?
- From Her Goody Bag...Shoe Therapy: The Transition Great shoes for now and later!
- K is for Kinky shows you the correct way to care for your lingerie...Just in time for V Day
- The Style Aficionado shows you how to revive your dried out creme liner
- And from The Glamour Whore Here's to hoping MAC's latest collection lives up to it's name...
- Project Danielle thinks its a great time to stock up on your favorite drugstore brands at Rite Aid
- Hot Beauty Health brings us Spring 2010 Beauty Trends
- We get a review of Zoya Reverie Nail Polish Collection (part 2) from Polish Swatches
- Retrodiva visits Susan Posnick Cosmetics headquarters and gets a tutorial on how to use mineral makeup
- Makeup Music Money Me shows you what do you do with your gift bags and boxes
- Diary of a Style Addict is looking for a change and found them in Korean Circle Contact lenses.
- Sparkle Crack Central Gives a review of Cover Girl's Lash Blast mascaras


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Kevin Love says call from LeBron helped make decision
Kevin Love's decision to sign with the Cleveland Cavaliers was helped by a phone call.
Well, more specifically, a phone call from LeBron James.
"LeBron signed to come back with the Cleveland Cavaliers, and a just few hours post he called me and I said, "you know what, 'I'm in,' " Love said "That had a lot to do with my decision."
The Cavaliers introduced Love as the newest member of the team's makeover that began with the signing of James in free agency.
Love spent his first six seasons with the Minnesota Timberwolves, who received Cleveland's 2014 No. 1 overall pick Andrew Wiggins and 2013 No. 1 overall pick Anthony Bennett. The Philadelphia 76ers were part of the trade as well, sending Thaddeus Young to the Timberwolves for guard Alexey Shved and forward Luc Mbah a Moute, along with the rights to the Miami Heat's 2015 first-round pick through the Cavaliers.
Love has never made the playoffs, but that should change on this team. The trio of Love, James and All-Star point guard Kyrie Irving gives Cleveland an exciting Big 3 that will be difficult for teams to defend.
"The endgame is always tough," Love said. "You know, the work I think we'll be able to put in every day and the culture that we'll have here that Griff (Cavs general manager David Griffin) and (owner) Dan Gilbert have set up for us, that culture is going to allow us to work every day. And for us, that will be gratifying. That's what I'm looking forward to, is every day continuing to get better."
Love was asked if he could talk about how long he might be in Cleveland.
"That is something that hasn't been talked about," Love said. "But like I told Griff and Dan Gilbert as well that I"m committed to this team. I'm committed long term to the end goal and that's to win championships here in Ohio."
Love, who is a career 19 point scorer and 12 rebound player, said he has patterned his game after Dirk Nowitzki. He worked on playing inside and outside.
As far as making the adjustment to the Cavaliers from his six seasons in Minnesota, Love went down the Cleveland roster and how he knows each guy.
"I loved my time in Minnesota," Love said. "It was a great six years and I enjoyed my time."


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Follows on the success of Special Edition release of The Secret of Monkey Island, Monkey Island 2 brings back the beloved sequel with exciting new features including high-definition graphics, a re-mastered musical score, full voiceover, and an in-depth hint system. Plus, experience all new unique special edition features that let you interact with the world of Monkey Island like never before.
Having defeated the evil ghost pirate LeChuck in his first adventure, pirate extraordinaire Guybrush Threepwood sets his sights on the treasure of Big Whoop. Legendary treasures however, come with legendary challenges and Guybrush will have to use his wits and humor to prove himself the greatest pirate in the Caribbean. Voodoo dolls, spitting contests and amusement parks are just some of the challenges Guybrush must overcome as he meets old friends, fights familiar enemies and uses every single ounce of his wits to become the most celebrated pirate ever.
A year ago LucasArts invited gamers to revisit its 1990 PC pirate adventure classic, The Secret of Monkey Island. The graphically enhanced remake quickly shot up the Xbox Live charts and earned enough critical praise that LucasArts decided to do it again. Monkey Island 2 Special Edition: LeChuck's Revenge is coming to Live, PSN, and PC this summer. Read More »
Also known as: Monkey Island 2, The Secret of Monkey Island 2: LeChuck's Revenge [series title]
Release Region: United States
Release Date: July 7, 2010
Publisher: LucasArts
Release Region: United Kingdom
Release Date: July 6, 2010
Publisher: LucasArts
Release Region: Australia
Release Date: July 6, 2010
Publisher: LucasArts
Monkey Island 2: LeChu... at IGN
Monkey Island 2: LeChu... at GameSpy
Monkey Island 2: LeChu... at TeamXbox
Monkey Island 2: LeChu... at GameStats


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Religious freedom office defended by Baird
Foreign Affairs Minister John Baird says his department's new Office of Religious Freedom won't become a vehicle for playing domestic politics in Canada's immigrant communities.
Baird dismissed criticism that the new office could lead to an uncomfortable mix of religion and politics.
"Freedom of religion is one of the first things in the Charter, it's one of the first things in the Bill of Rights, it's front and centre in the UN Declaration of Human Rights – it's an essential human right; I don't see any concern about that at all," Baird told The Canadian Press in a year-end interview.
The Tories announced the creation of the office in their federal election platform last spring, but they have yet to roll out details of the new entity, to be housed within Foreign Affairs. The government is expected to formally announce the new office early this year.
Baird has high hopes for the Office of Religious Freedom, even though it will come with a modest $5-million price tag. That will include a relatively minuscule $500,000 budget for operations, so it won't be a major drag on already thin resources.
But some are warning the office could have a broad impact, and not the positive one the Conservative government is looking for.
Tories accused of secrecy over new office
Alex Neve, the head of Amnesty International Canada, says that while religious persecution "is a serious human rights concern right around the world" he's not confident about the government's approach to the new office.
"We're watching it with interest but also with considerable concern," said Neve. "There is such complete secrecy about it." His organization has met with Foreign Affairs officials, but questions about the office generate vague responses along the lines of "work is under way" and "you'll be hearing more," said Neve.
Neve said religious freedom can have a "contentious relationship" with other crucial human-rights concerns such as women's equality, the equality rights of gays and lesbians, and freedom of expression.
"It's an area obviously where governments need to tread carefully. They need to do so in ways where they don't – either intentionally or unintentionally – convey a message that some religions are preferred over others."
Baird has been consulting internationally, including meetings with the Vatican in Rome and a day of consultations in Ottawa with religious groups in October.
The October consultations were not open to the public. Neve questions why Amnesty and other rights groups were excluded.
Baird offered few details about how the new office will actually function during a pre-Christmas interview.
Details still to come
"It's in the campaign document. What you see is what you get. There won't be any surprises," the minister said, adding he would be "speaking to it in the new year."
Pressed on what exactly the office will do, Baird replied: "It will be promoting religious freedom." He said it would involve "persuasion, lobbying, putting light ... promoting."
The Tories have noted that the concept of the office is not novel to Canada. They point to the fact the U.S. State Department has its own religious freedom office that was created in the late 1990s under the Democratic administration of Bill Clinton.
A May briefing note to Baird, obtained under Access to Information, lays out three priority areas for the new office: protecting, and advocating on behalf of, religious minorities under threat; opposing religious hatred and intolerance; promoting the Canadian values of pluralism and tolerance abroad.
Baird has consulted internationally on the creation of the new office meeting with the Holy See in Rome, the Aga Khan, head of the Greek Orthodox Church in Turkey and the U.S. ambassador at large for international religious freedom.
"They accomplished a lot," Baird said of his meeting last summer with Suzan Johnson Cook, the U.S. Ambassador-at-Large for International Religious Freedom.
But he added "ours will be a made-in-Canada approach."
Baird cited persecution of Baha'i practitioners in Iran, Coptic Christians killed in Egypt and Roman Catholic priests who have been forced underground in China. "Sometimes tough things need to be said. It's really uncomfortable, I think, for the Egyptian government when you talk about the plight of Copts," said Baird.
"If you're one of the 54 Copts who was killed at this time last year, it's pretty uncomfortable for you and your family too, whose only sin was being Coptic."
As the Tories mull their final roll out for the new office, religious violence is sparking the usual time-honoured response of Canadian governments, whether Liberal or Conservative: a written denunciation in the minister's name condemning the perpetrators and an expression of solidarity for the victims.
That's what happened on Christmas Day after a radical sect called Boko Haram claimed responsibility for a series of attacks on churches that killed at least 42 people in Nigeria. Baird's statement that day said: "Our thoughts and prayers are with the victims and their loved ones. These people died practising their religion – a basic human right. Canada strongly denounces such cowardly attacks without reservation."


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Modern frugality isn't about clipping coupons and eating gruel (although, in a pinch, both can work). Find out how much frugal living has to offer.
Being short on a few winks is bad for more than just your health. A bad night's sleep can lead to many harmful money mistakes, too.
Whether it's something as big as a career move or as small as what you're having for dinner, follow these tips to help make great decisions.
With all the information we're faced with every day, it can be hard to know what's what. These seven steps will help you get closer to the truth.
One writer was taught when she was very young — it's a commitment to the little things that makes the big things work.
At 94, my grandmother is as independent, effervescent, and opinionated as ever, and she has some good (and surprising) advice about making decisions.
Sometimes there's just one moment, one little thing that makes us change our lives for the better. Did you have a financial fork in the road?
You can't get there from here if you don't know where you are.
It's easy to avoid making purchases you'll regret later; learn the 14 questions to ask yourself before you buy something new.
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KUALA LUMPUR, Malaysia, Oct. 27 (UPI) -- Ryan Moore rolled in a short birdie on the first playoff hole Monday, edging Gary Woodland to win the rain-delayed CIMB Classic in Malaysia.
Moore (2-under 70) and Woodland (69) each ended 72 holes at 14-under-par 274 Sunday, forcing a Monday playoff after darkness halted play following a pair of lengthy rain delays.
Woodland had a chance to win the event on the 18th hole, but missed a 12-foot birdie putt try while Moore carded a par from in front of the green.
On the playoff hole, Woodland found the rough on his lay-up shot while Moore put his approach within 4 feet of the pin.
Woodland again landed in the rough with his third shot and his chip stopped just a foot shy of the hole, leaving Moore free to drain a birdie for his third career PGA win.
Third-round co-leader Chris Stroud managed a 71 Sunday, ending in a tie for third place at minus-13 with Thailand's Kiradech Aphibarnrat (70).
Sole possession of fifth place at 12-under went to Aaron Baddeley (66), while Jimmy Walker (68) claimed sixth one shot further back.
Charles Howell III (68), Harris English (69) and Graham DeLaet (71) shared seventh place at 10-under.


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Reproductive Endocrinology Assays
Measurements of alpha-fetoprotein (AFP) are used as an aid in managing non-seminomatous testicular cancer when used in conjunction with physical examination, histology/pathology, and other clinical evaluation procedures. It is also used to measure maternal serum and amniotic fluid during gestational weeks 15 through 20 – used in conjunction with ultrasonography or amniography – to aid in the detection of fetal open neural tube defects.
Androstenedione is a useful aid in the diagnosis of various pathologies, including male and female infertility. This steroid is the common precursor to testosterone and estrone in the endogenous synthetic pathways of androgens and estrogens.
DHEAS assists in the evaluation of patients with infertility, polycystic ovarian syndrome, amenorrhea, abnormal hair growth (hirsutism) and balding (alopecia) in women. It is also of value in the assessment of adrenarche and delayed puberty.
DHEAS spec sheet 0.2 MB
'Evaluation of a new DHEAS assay on the ADVIA Centaur system' white paper 0.2 MB
Of the various estrogens, estradiol is the most potent. Measurements are used for monitoring ovulation induction and in the differential diagnosis of amenorrhea and precocious puberty in girls. Estradiol has also proven to be useful in evaluating clinical conditions in the male such as hypogonadism.
White Paper "ADVIA Centaur® Enhanced Estradiol Assay: Performance and Standardization" 1.5 MB
"Performance Evaluation of Siemens' ADVIA Centaur® Enhanced Estradiol Assay and A Split Comparison with LC-MS/MS" Clinical Biochemistry July 2012 PubMed
Free Beta HCG1
Measurements of free βHCG levels have been found to aid in the diagnosis and monitoring of trophoblastic diseases (moles, choriocarcinoma) and certain testicular tumors, where the ratios of the free β subunit to intact HCG can be quite high. Free βHCG may also have clinical utility in first-and second-trimester prenatal screening for Down syndrome and other chromosomal anomalies.
Follicle-stimulating hormone induces ovarian follicular growth and stimulates follicular secretion of estradiol in the female. In the male, it facilitates the development of the testes and stimulates spermatogenesis. It is particularly useful in the clinical evaluation of infertility and menopause.
Performance of LOCI assays for FSH, LH, and Prolactin on the Dimension Vista System 0.3 MB
Human chorionic gonadotropin (HCG) is commonly used to confirm and monitor pregnancy, but also has clinical utility in detection of miscarriages, preeclampsia, neoplasms, trophoblastic diseases, and risk calculations for Trisomy-21 and Trisomy-18.
IMMULTE HCG and Subunits: Assay Specificities and Clinical Utility in Obstetrical Care 0.3 MB
Luteinizing hormone promotes ovulation and the production of estrogen and progesterone. In the male, it stimulates the testes to produce androgens and estrogens. Measurements of LH are used in the clinical evaluation of various conditions including infertility, hypogonadism and menopause.
Performance of LOCI assays for FSH, LH, and Prolactin on the Dimension Vista System 0.3 MB
Pregnancy-associated plasma protein-A (PAPP-A) is used to screen pregnant women in the first trimester of their pregnancy to assess the risk that the fetus they are carrying may have a chromosomal abnormality such as Down syndrome (Trisomy 21) or Edward's syndrome (Trisomy18).
Among its many important functions, progesterone acts in concert with estradiol to control the phases of the menstrual cycle; it also maintains the fetus during early pregnancy. Progesterone measurement is indicated in conditions such as infertility, normal and ectopic pregnancy, and menopause.
Progesterone: Physiology and Clinical Utility 0.2 MB
Prolactin is used as an aid in the diagnosis and treatment of pituitary disorders. It plays an essential role in the secretion of milk and has the ability to suppress gonadal function. Determination of prolactin has become an important tool in the investigation of amenorrhea, galactorrhea and hypothalamic-pituitary disorders.
Performance of LOCI assays for FSH, LH, and Prolactin on the Dimension Vista System 0.3 MB
SHBG measurements are useful in the evaluation of androgen disorders including virilization, hirsutism and polycystic ovary syndrome. SHBG typically circulates at higher concentrations in women than in men, because of the higher ratio of estrogens to androgens in women. For the same reason, SHBG levels in late pregnancy or after estrogen administration may be especially elevated. Administration tends to be associated with decreased SHBG levels. The SHBG assay from Siemens meets the clinician's need for effective and efficient monitoring of androgen status.
'SHBG and the Assessment of Androgen Status' white paper 0.1 MB
'Development of a New Sex-Hormone Binding Globulin (sHBG) Assay on the ADVIA Centaur System 0.2 MB
Validation of SHBG immunoassay on the Centaur 0.4 MB
Testosterone measures are helpful in the evaluation of hypogonadal states in males, and hirsutism and virilism in females. Siemens offers assays for both testosterone and SHBG. When these assays are used in combination, the free androgen index can be calculated from results obtained with the ease and efficiency of an automated system.
Exploring the Free Androgen Index: User-friendly calculator to facilitate the joint assessment of testosterone and SHBG levels in adults.
Unconjugated Estriol
UE3 is used as an aid in monitoring fetal maturity and well-being in the context of high-risk and poorly dated pregnancies. The unconjugated estriol assay from Siemens offers standardization to GC/MS, excellent precision, improved analytical and functional sensitivity and specificity.
Performance of an Improved Automated Chemiluminescent Assay for Unconjugated Estriol on the IMMULITE® 2000 Analyzer 0.2 MB
*Product availability may vary from country to country and is subject to varying regulatory requirements.
1. Not available for sale in the U.S. or Canada.
2. Under FDA review. Not available for sale in the U.S.
For additional information on Siemens' broad range of instruments, assays, and solutions, contact your local Siemens representative or click on the link above.
The products/features (mentioned herein) are not commercially available in all countries. Due to regulatory reasons their future availability cannot be guaranteed. Please contact your local Siemens Healthineers organization for further details.


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In 2002, Bill Gates predicted the majority of PCs shipped by now would be tablet PCs, but their numbers are still just a fraction of the market and account for less than 2 percent of all laptop computers shipped.
While tablet PCs are accepted in increasing numbers by medical personnel, insurance adjusters and other vertical users, why haven't they gone mainstream?
Analysts cite at least eight reasons why tablets haven't done better, including their higher cost compared with standard laptops (up to US$300 more), problems with touch technology and handwriting recognition software, and a shortage of suitable applications.
Recognizing those problems, tablet PC makers recently introduced new second- and third-generation devices in both the convertible and slate form factors. More new models are expected later this year running the Vista operating system, which will eliminate the separate Tablet PC Edition in Windows XP and the resulting inefficiencies, analysts said.
"Tablet PCs remain a niche product in the marketplace, used predominantly in vertical applications," said Leslie Fiering, an analyst at Gartner Inc. in a recent conference presentation. The tablet PC's "appeal to horizontal, mainstream users will continue to be minimal" because of higher costs, an "immature" touch interface and other factors, she added.
Fiering, who started following tablet PC trends at their introduction in 2002, makes the strongest condemnations of tablet PCs of five analysts interviewed for this story, but she also offers the greatest optimism.
In an interview, Fiering said she is still "bullish" about what the tablet PC can become. "It's important technology which is slow in coming," she said. "A lot of things have to fall in place, but it's real."
The tablet PC market has tracked fairly closely to Gartner's forecasts, although well behind what Gates was hoping for. Microsoft predicted sales of 1 million tablets in all of 2003, she said, while Gartner predicted sales of 230,000, about 5,000 higher than actual shipments, she said. That 1 million mark was finally reached in 2006.
Several analysts said they have had to consistently revise their forecasts downward for tablet PCs. About 18 months ago, market research firm IDC forecast 7 million tablets would ship in 2010, and last year revised the number down to 5 million, said IDC analyst Richard Shim. Gartner expects the 5 million mark to be hit in 2009.
IDC puts total tablet PCs at only 2 percent of all laptops that shipped last year, a number that might exceed 3 percent this year, Shim said. Other analysts said the amount is less than 2 percent.
"The forecasts have definitely been reduced since they first came out," Shim said. "A lot of hype has been built ... by Microsoft."
Slowness in sales of tablet PCs means nothing to many happy users, however. For example, at the Altoona police department in Wisconsin, U.S., two Lenovo ThinkPad X41 Tablet PCs have been in use inside police vehicles since 2005, and the department is planning to add as many as 15 newer models in the next year, said Officer Dana Brown, manager of the department's technology initiatives.
"There was a US$200 premium over a standard laptop, but we wanted the versatility, and it has definitely paid off," Brown said. "We're getting away from the keyboard ... Tablets are more than a niche for law enforcement."


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Games With Gold December 2019: Last Chance For These Xbox One Games
Two of the four Xbox One games have cycled out, but two more games are now available for free until the end of the month.
Two of the four Xbox One games have cycled out, but two more games are now available for free until the end of the month.
Lost Odyssey and more can now be played on Xbox One.
Microsoft's family focus sees fan-favorite Pixar characters star in minigame collection; Double Fine developing new kid-friendly experience.
Crimson Red and Cosmic Blue colors on sale this Thursday; Toy Story 3 bundle out in August.
Microsoft's online platform updated with new content for People Can Fly's shooter; Games on Demand adds Toy Story 3, Raven Squad, and Sonic and Sega All Stars with Banjo Kazooie.
Heavy Rain proves a critical favourite, picking up three British Academy awards; Mass Effect 2 wins the Best Game prize; Peter Molyneux awarded the BAFTA Fellowship for lifetime achievement.
Sony announces new milestone for home console since debuting in Japan in March 2000; 10,828 titles available, 1.52 billion software units sold since launch.
Company's Interactive arm grows revenue 58 percent to $349 million, citing success of Junction Point's Wii title, Toy Story 3.
Anniversary of October 26, 2000, US and Canadian launch sees aging console's sales top 146 million.
New $100 PlayStation 2 bundle includes copy of video game adaptation of this past summer's blockbuster.
EA's flagship football franchise flattens foes on its way to third-biggest UK launch ever, accounts for nearly two in three Xbox 360 and PS3 game sales.
NCAA Football 10 leads NPD's mostly surprise-free top 20 sales chart; Just Dance, New Super Mario Bros. DS continue sales run.
74% revenue bump from Split/Second and Toy Story 3 sales can't keep interactive media sector out of red; profits rise 40% company-wide.
UK Sales of the new Xbox 360 surpass launch sales of PS2 and PS3 Slim; match those of original Xbox 360.
Disney Interactive Studios' motion picture tie-in, Nintendo's 100 Classic Books, World War II submarine game Naval Assault: The Killing Tide highlight a slow week.
You're the sheriff of your own Western town in this Toy Story sandbox.
Disney's Avalanche Studios crafting film tie-in to launch alongside Pixar's latest animated action figure tale for 360, PS3, PSP, Wii, DS, PC.
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Company Name: Ward Electrical Installations Limited
Telephone: 01623 368603
Mobile: 07739 797422
Address:SUTTON IN ASHFIELD
Our Installer search facility is provided to enable you to find registered NAPIT tradespeople.
The private information contained herein is strictly for non-commercial use and is solely intended for the purpose it serves.
Any misuse of such information will be seen as a breach of our terms and conditions and could potentially incur legal proceedings.
Not all search parameters are expressly assessed by NAPIT and some are an opt-in preference available to the member.


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This module corresponds to section 3.1.2 (String Queries) and chapter 7 (Appendix: Extensions) of the OpenAL Specification and Reference (version 1.1).
alExtensions :: GettableStateVar [String]Source
Contains the list of available extensions.
alIsExtensionPresent :: String -> GettableStateVar BoolSource
To verify that a given extension is available for the current context, use
alIsExtensionPresent. For invalid and unsupported string tokens it contains
False. The extension name is not case sensitive: The implementation will
convert the name to all upper-case internally (and will express extension
names in upper-case).
alProcAddress :: String -> GettableStateVar (FunPtr a)Source
To retrieving function entry addresses, applications can use
alProcAddress. It contains
nullFunPtr if no entry point with the given
name can be found. Implementations are free to use
nullFunPtr if an
entry point is present, but not applicable for the current context. However
the specification does not guarantee this behavior. Applications can use
alProcAddress to obtain core API entry points, not just extensions. This
is the recommended way to dynamically load and unload OpenAL DLLs as sound
alEnumValue :: String -> GettableStateVar ALenumSource
To obtain enumeration values for extensions, the application has to use
alEnumValue of an extension token. Enumeration values are defined within
the OpenAL name space and allocated according to specification of the core
API and the extensions, thus they are context-independent.
alEnumValue contains 0 if the enumeration can not be found. The presence of
an enum value does not guarantee the applicability of an extension to the
current context. A non-zero value indicates merely that the implementation is
aware of the existence of this extension. Implementations should not attempt
to use 0 to indicate that the extensions is not supported for the current
alVersion :: GettableStateVar StringSource
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Lake Loop 2014
EVENT DATE: Oct 12, 2014
Nixon School
275 Mount Arlington Blvd
Landing, NJ 07850
Online Registration Closed
Online Registration Ends: 10/11/2014 (12 noon)
Pre-Registration is free when you raise a minimum of $35 for the cause. Day of Event Registration is a $50.00 flat fee and opens at 8am on October 12th. For those that want to check-in prior to the event, if you have cash or check donations to drop off, need some extra equipment or want to get your fundraising prizes early we will be at Marty's Reliable Cycle in Randolph on October 11th from 11-1pm.
A few important things you should know...
About the event...
Come enjoy breathtaking views of Lake Hopatcong on a scenic bike ride or 3-mile walk to raise funds for NJ's largest lake! The cycling course will go clockwise around the lake and consist of approximately 20 miles of rolling terrain. This course is not flat but, there are no significant hills that might deter those looking for an enjoyable ride. The 40 mile course includes a hilly 20 mile extension added to the middle of the 20 mile course. The 3 mile walk will take participants down through King's Cove and around Bertrand's Island before heading back to the finish line at Nixon School. 'GET FIT' for the lake, when you register and create your own fundraising page, reach out to friends and family to support you on your journey. Prizes will be awarded for fundraising accomplishments. An adult parent or guardian must accompany each rider younger than 18. No trikes or training wheeled bicycles allowed. Helmets are required. All fees and donations are non-refundable. This event will go on rain or shine.
Lake Loop 2014 includes organized ride, tour map of historical landmarks on route, prizes for top individual and team fundraisers, stocked rest stops, cue sheets, mechanical support, door prizes, SAG vehicle, post-ride music by Byrdgrass, food and fun! First wave leaves at 9:30am from Nixon School.
Click Here to download the Lake Loop 2014 Flyer.
Day of Event Schedule:
Day of Event Registration ($50 flat fee) and Check-in: 8am
Dunkin Donuts coffee will be available at check-in. Mechanical support will abe available for riders. Lake Loop welcomes TransOptions, Inc. to Lake Loop 2014. Stop by their table, get information on bike safety and a free helmet fitting. Fitness Innovations will be doing warm-up's for our participants after check-in.
40 Mile Cyclists Depart: 9:30am
20 Mile Cyclists Depart: 9:45 am
3 Mile Walkers Depart: 10am
Food will be served 11:15-1:30
When you return from you walk or ride take pictures at our TapSnap photobooth, enjoy great food and music, VIP's (those that raised $500 or more) can enjoy the VIP tent with massage and more.
GET FIT for the lake fundraising...
Check out fundraising incentives under the GET FIT for the lake tab below. Participants who raises more than $100 will receive an event item. We are thrilled to announce an exciting team prize. The top fundraising team PRIZE will be a group rental on Miss Lotta, check out the boat at lakehopatcongcruises.com
Need help with your fundraising effort? Check this out...Individual Fundraising Letter Lake Loop and Lake Loop Paper Pledge Form. Personalize the letter and use it to let people know about the great things the LHF is up to.
Participants must sign a waiver. We will have printed waivers to sign upon check-in. If you want to expedite the process print and bring your waiver to registration.
CLICK HERE to print off your Walker Waiver.
CLICK HERE to print off your Cyclist Waiver
About the Lake Hopatcong Foundation
Proceeds for this event will support The Lake Hopatcong Foundation, a 501c3 non-profit organization dedicated to improving Lake Hopatcong for everyone now and in the years to come. The purpose of the Foundation is far-reaching, and includes everything from public safety to community cohesiveness, to historical preservation, but its core initiative is to keep the lake clean. To learn more about the Foundation's important initiatives visit LakeHopatcongFoundation.org
Visit us at LakeHopatcongFoundation.org
Contact us
Questions contact Becky Rubenstein at email@example.com or by phone at 973-663-2500
Top 10 Reasons to GET FIT for the lake!
Click here for the Top 10 Reasons to participate in Lake Loop 2014
The Route
Click the below links to see the routes:
3 Mile Walk: http://ridewithgps.com/routes/5169501
40 Mile Route: http://ridewithgps.com/routes/5169368
20 Mile Route: http://ridewithgps.com/routes/5169262
Click Here for a list of historic landmarks you will pass on the ride and Click Here for a coordinating map of the lake showing where the landmarks are located.
Lake Hopatcong Foundation thanks our generous sponsors Marty's Reliable Cycle, PowerBar, Taco Truck, Dunkin Donuts, BTS Landscaping, Salmon Brothers, TapSnap, Kimberly Hipwell with Remax House Values, Revolution Indoor Cycling Studio, Mogavero's Fitness Innovations, Shoprite. Would you like to become a sponsor, email firstname.lastname@example.com


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A devastated world…
Blistering combat
Take control of YoRHa 2B, the most advanced combat android ever built, and embark on a perilous mission to retake your home world in this PlayStation 4 exclusive sequel to PS3 fan favourite NieR.
Follow the events that unfold after the original game and discover a future in which mankind has been driven from the planet by an invading mechanized force. As a weapon of the human resistance, return to the surface to do battle with the gigantic mechanical weapons who've laid waste to civilization.
Explore the deserted lands discovering more about the mysterious events which shaped mankind's ill fortunes and work to set the record straight with devastating, high-speed combos and slick takedowns.


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RALEIGH, N.C. — C.J. Leslie and Richard Howell just weren't going to let this game get away. It's why No. 20 North Carolina State celebrated a huge win against No. 1 Duke.
Leslie scored 25 points, including six straight during a key second-half run, to help the Wolfpack beat the Blue Devils 84-76 on Saturday.
Howell added 16 points and 18 rebounds in a relentless performance for the Wolfpack (14-2, 3-0 Atlantic Coast Conference) in a matchup of the teams predicted to finish 1-2 in the league.
N.C. State was picked for the first time in nearly four decades to win the league, though two early losses drained some buzz.
No longer. Now N.C. State is back on everyone's radar, while the Blue Devils (15-1, 2-1) are no longer unbeaten.
Seth Curry scored 22 despite missing the final minutes with an ankle injury for Duke, which shot 45 percent and hung around early by crashing the boards for second-chance baskets. But the Blue Devils had no answer after halftime for Leslie and Howell, a duo that helped the Wolfpack lead all second half.
"They played well," Duke Coach Mike Krzyzewski said. "I thought we played our butts off. … Our kids played with a lot of heart, their kids played with a lot of heart, and they were a little better than we were."
Fittingly, Howell hauled in the rebound on Duke's final shot to end this one, then passed the ball to Lorenzo Brown as Leslie began jumping around near midcourt to celebrate. As the horn sounded, Brown flung the ball high into the air while students and Wolfpack fans stormed to the court – the charge led by a fan in a wheelchair – to celebrate.
Fans soon lifted Leslie and Brown on their shoulders amid the sea of red-clad celebration.
"I saw the whole court and I couldn't see a bit of court," Leslie said. "I couldn't see one part of the floor. It was just people everywhere. So that's going to be a remembrance that we'll never forget. We'll always keep this in our minds."
This was the kind of moment N.C. State fans long hungry to challenge perennial heavyweights Duke and North Carolina atop the league have been hoping for all season. Their team certainly rose to the occasion, whether it was Leslie performing to his status as the preseason ACC player of the year or Howell attacking the boards and scoring on second-half putbacks that fully seized momentum for N.C. State.
With his team protecting a 58-57 lead, Leslie went to work, knocking down a jumper then getting past Josh Hairston in the lane for another bucket. On the next possession, he muscled the ball up between two defenders, and soon the Wolfpack pushed its biggest lead to 67-57 with 7:44 left.
The Blue Devils got no closer than four again, with Leslie scoring over Mason Plumlee inside to answer the Blue Devils' last push with 1:41 left. The Wolfpack closed this one out confidently, hitting eight straight and 9 of 10 free throws in the final minute to stay in front.
N.C. State shot 51 percent to earn its 10th straight win and its first 3-0 start in ACC play since the 1988-89 season.
The Blue Devils played the final 3-plus minutes without Curry, who crumpled to the court after slipping on a wet spot on the court. They were already without starting forward Ryan Kelly, who it out indefinitely with a foot injury and was on crutches on the Duke bench for this one.
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Letters to the Editor
Curry focuses on county's top issues
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Senate District 13 blessed to have Maxmin


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Jovica Storer
(listen - ambient - electronical)
Jovica Storer is Jovica Storer.
Well, OK, that was maybe a bit too easy. Let us have a look what is said on his myspace page:
Joost Carpentier (aka Jovica Storer) is a Belgian electronic music composer/producer who has been addicted to aural vibrations ever since his youth. He learned to play the piano as a child an started improvising his own creations as a teenager. After being a radio jockey for several years, he went DJ-ing in several pubs and on local parties. In his early twenties he bought his first synthesizer and a computer and started sequencing. Since that day in the summer of 1989, he has never ceased to explore new territory on the planet of electronic sound.
Visit this man on: http://profile.myspace.com/jovicastorer
You can also check his favorite links on our site.
Jovica Storer explores his borderlines and proposes new work where no genre will be untouched.
Electronic Innerscapes REMASTERED! 31 colourful photorealistic heart opening aural paintings.
Finally back and fully REMASTERED on C-O-L-O-U-R-S. 3 hours of music! This masterpiece is a perfect match for the seekers of inspirational atmospheres.
Following the exhibition "Innerlijk Ritme" (= "inner rhythm"), Jovica Storer sets off again with a vivid and moving musical journey of more than four hours.
In cooperation with haiku-master Geert Verbeke who added wonderful singing bowls flavours. Element is an aural interpretation of the five Japanese Elements. This is a remaster of a succesful musical milestone by Jovica Storer.


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Wreaths, Garlands & Swags
Alpine Frost 24" Holiday Wreath
Alpine Frost Holiday Teardrop
Lemon & Hydrangea
Faux Flower Wreath
Ranunculus & Lavender
Silk Flower Wreath
Eucalyptus Artificial Foliage Wreath
Wild Fern & Berry
Faux Foliage Wreath
Pansy & Dianthus Silk Flower Wreath
Zinnia & Daisy Silk Flower Wreath
Daisy & Sunflower
Silk Flower Wreath
Graciously welcome guests to your home with a lovely decorative wreath hung on your front door. Add a touch of seasonal color to a wall space or above the mantle. Our collection of artificial wreaths, swags, and garlands make seasonal decorating quick, easy, and fun. All of our welcoming designs arrive expertly packaged, ready to hang, and backed by our 100% Customer Satisfaction Guarantee!


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Download link (right click and 'save-as') for playing in VLC or other compatible player.
Recent experimental evidence suggests that living organisms are using quantum mechanics in a sophisticated fashion to enhance the efficiency of photosynthesis. Bacteria are essentially performing a quantum computation to extract energy from light. I will show how plants and bacteria perform quantum information processing, and will discuss how living creatures engage in all sorts of quantum hanky-panky in their efforts to survive and reproduce.


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Pictures and Review of the 2012 Fall Couture Chanel Show
2012 Paris Couture Fashion Week: Chanel
2012 Paris Couture Fashion Week: Chanel
Karl Lagerfeld showed Chanel's Fall 2012 Couture collection in Paris's Grand Palais to a star-studded crowd that included Diane Kruger, Clémence Poésy, and Sofia Coppola. Themed "new vintage," the collection highlighted a chic array of the brand's signature tweed cut in true ladylike fashion — skirt sets, dresses paired with cropped jackets, and slouched trouser suits inspired by Coco Chanel all emoted an understated elegance, while slouched beanies and metallic tights injected a dose of modernity. But that's not to say the drama was missing, as eveningwear highlighted the designer's decadent side. Lagerfeld's intricately beaded separates, silver lurex gowns, and silk dresses were the perfect mix of vintage modern glamour. However, the pièce de résistance was the closing look worn by Lindsey Wixson: a white tulle and pearl embellished gown, which reportedly took over 3,000 hours to make. More details from the collection below.
- Trends: Ladylike tweed, metallics, loose trousers, beading.
- Colours: Grey, pink, purple, black, silver, blush.
- Key Piece: The slouched trouser sets and jaw-dropping tulle and pearl embellished white gown.
- Accessories: Metal cap-toe pumps, metallic leather fingerless gloves, metal belts, slouched beanies, shimmer tights.
- Who Would Wear It: Girls who crave chic looks with a twist like front-row attendees Diane Kruger and Clémence Poésy.


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Wearing: Brandy Melville Sweater | All Saints Jeans | Deena&Ozzy Oxfords | Alexander McQueen Bangle | Remi&Emmy Bags
Loving all my new purchases featured in this post…and even more excited to introduce you guys to one my favorite new handbag lines, Remi&Emmy. The uptown girl in a downtown world inspired collection was designed for bloggers and street stylists that inspired the creators. And, guess who was one of them? ME! I worked with several other bloggers in the design collective for Remi&Emmy and can confidently say we did an awesome job. Check out more from the line here. Remi&Emmy is available exclusively at Dillards & Lord & Taylor.
For my outfit: The All Saints jeans that come in five other colors are the perfect fitting skinny jean and you can't see it here, but they have zippers on the back ankle. Yes, and bought a second pair too. My other new purchase are these oxfords that are on sale at Urban Outfitters for super cheap; if you haven't realized yet, I love my oxfords and have this pair in the tan color (I spray painted the tips recently).


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State Police blotter for Jan. 20
Sunday, Jan. 20
* Michael A. Holder, 53, of Poland, was charged with driving while intoxicated and aggravated driving while intoxicated.
* Eden M. Sumderman, 44, of Cazenovia, was charged with an inadequate plate lamp, operation of a motor vehicle with a blood alcohol content of .08 percent and driving while intoxicated.
* Kenneth M. Merriman, 30, of Hamilton, was charged with petty larceny.
* Ian Nasutowicz, 20, of Vernon, was charged with driving while intoxicated, operating a motor vehicle with blood alcohol content of .08 of one percent or higher, and unlawful possession of alcohol by a person under 21.


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Recipe from Travis Perkins of La.
4 boneless skinless chicken breasts
1 stick of butter
1 can of cream of chicken soup
1 to 1&1/2 cups grated cheddar cheese
4 medium butter gold potatoes
Melt butter in skillet and brown the chicken breasts. Place breasts in casserole dish. Preheat oven to 300 degrees. Mix soup with butter and stir until smooth; I rinse the can with a little water. Pour soup/butter mixture over chicken breast and top with grated cheese. Bake one hour. Cut potatoes into about 1 inch squares and fry, then salt. Top chicken and cheese with fried potato squares and serve.
*DISCLAIMER*: The information contained in or provided through this site section is intended for general consumer understanding and education only and is not intended to be and is not a substitute for professional advice. Use of this site section and any information contained on or provided through this site section is at your own risk and any information contained on or provided through this site section is provided on an "as is" basis without any representations or warranties.


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+ Add kit to stash (beta) + Add new Blog/Work in Progress + Request instruction + Upload new instruction
"It is more blessed to give than receive"
Upload unique instruction to get 10 extra points right after my approve.
Upload unique instruction to get 10 extra points right after my approve.
Click on advertise to get +3 extra point.
Blogs Alert From now, You can share Your modelling Work in Progress at: Blogs section
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M3A3 Bradley CFV Standard Edition
Serial no.: IM002
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text: Aspergillus terreus Thom (ATCC® 20542D-2™) Strain Designations: Genomic DNA from Aspergillus terreus strain MF4845 (ATCC® 20542™) / Product Format: dried Total DNA: Approximately 2µg of DNAOD260/OD280: 1.7-2.0 General Information Characteristics History Documentation Print Email Share Share this product Facebook Twitter Google+ Permits and Restrictions View Permits Strain Designations Genomic DNA from Aspergillus terreus strain MF4845 (ATCC® 20542™) Biosafety Level 1 Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. Product Format dried Total DNA: Approximately 2µg of DNAOD260/OD280: 1.7-2.0 Type Strain no Preceptrol® no Genome Sequenced Strain Yes Comments This preparation of high molecular weight DNA is appropriate for the use in the polymerase chain reaction (PCR)* process and other molecular biology applications. *The PCR process is covered by patents owned by Hoffmann-La Roche Inc. Use of the PCR process requires a license. Genomic DNA from Genome sequencing strain (Microbia, Inc., USA). Our DNA sequencing results raised the question about the strain's identity as Aspergillus terreus. Further investigation is planned. Name of Depositor ATCC Special Collection DNA Cross References Nucleotide (GenBank) : AABT01000000 Aspergillus terreus ATCC 20542, whole genome shotgun sequencing project. Permits These permits may be required for shipping this product: Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment. Basic Documentation Product Sheet Certificate of Analysis SDS


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I dont get it.
Ragnarok Arena is a sidescrolling multiplayer shooter developed on the Source Engine. Gameplay is brutal and fast paced, with realism being thrown to the side in exchange for adrenaline-fueled arcade action. Relive the joy of playing in the style of older titles like Mega Man, Contra and Metal Slug with friends in eye-popping HD, and with a new control scheme custom-tuned for a keyboard and mouse.
I dont get it.
Well, it means I haven't experienced an early death, for one.
Only registered members can share their thoughts. So come on! Join the community today (totally free - or sign in with your social account on the right) and join in the conversation.
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text: Fluids and gases can move in strange and mysterious ways that aren't always apparent to our unaided eyes. It's only with the use of tracers or dyes, photographic techniques and a bit of luck, that we can capture fluid dynamics in action. Here are some of the weird and beautiful ways in which fluids flow. Above: Supersonic Shock Wave When an object moves faster than the speed of sound, funny things start to happen. The bullet in the image above is moving so fast, the air in front of it can't get out of the way quickly enough. So it starts to pile up in front of the bullet, forming an area of compressed air — a shock wave. The same thing happens with supersonic jets. As they fly faster than the speed of sound, they build up a shock wave in front of them. The sonic boom that accompanies these aircraft is actually the wave of compressed air hurtling by your ears. Image: Andrew Davidhazy/Rochester Institute of TechnologyVon Karman Vortex Streets In the image above, winds blowing cloud cover over the Pacific Ocean encounter obstacles in the form of Alaska's Aleutian Islands. Two of the islands are visible as darker spots on the right side of the image. When flows like air currents encounter an object like an island, they split and go around the obstacle. This sets up a low-pressure area just behind the object. As the air comes around the island, the flows curl in toward the low pressure. This curl, or vortex, acquires a spin and breaks off from the rest of the stream. The flows alternate spinning off vortices, forming a trailing line of swirling clouds. Images: 1) U.S. Geological Survey/NASA. 2) NASA/MODIS.Inverted Drafting Inverted drafting happens when a leading object encounters less drag than the object behind it. An example is when flows encounter passive objects, like flags, arranged one behind the other. Flags are considered passive because they flop around with every shifting breeze, unlike humans who are considered rigid objects. In this image, two white, S-shaped lines are flags oriented one behind the other. The flag in the follower position cuts into the wake given off by the flag out front. By cutting into the leader's wake, the follower reduces the overall resistance the leader experiences. Image: Leif Ristroph and Jun Zhang/New York UniversitySaffman-Taylor Instability These beautiful patterns are the result of interactions between fluids of different viscosity, which is a measure of how thick a liquid is. For example, water is less viscous than honey. In the first image below, a viscous fluid called glycerin is sandwiched between two clear plates. When a less viscous fluid like water is injected into the glycerin, the water intrudes in the form of fingers. The pattern grows when the finger tips split into more fingers. Video: Jessica Rosenkrantz. Images: 1) Dustin Grace, Jessica Todd, Marilyn Poon, and Robert Neilson/University of Colorado. 2) Jessica Rosenkrantz/FlickrConvection A classic example of convection begins with the goblet in the image above filled with warm water. As the air around the glass heats up, it begins to rise. Eventually the air will lose its heat to the surrounding environment, cool and then sink back down. In the second image, an ice cube floating in a pool of water cools the liquid around it. Since cold water is more dense than warm water, the heavier liquid begins to sink. Images: 1) Andrew Davidhazy/Rochester Institute of Technology. 2) J. Kim Vandiver and Harold E. Edgerton/MITCavitation When an object like a propeller blade moves through a fluid with enough speed, it creates a void in the liquid. That cavity, or bubble, collapses in on itself, generating shock waves and jets of water. Cavitation bubbles can also form when a small area of water is hit by an electric spark or laser, as in the video below. This creates a bubble of gas that quickly implodes, also generating shock waves and water jets. In the image above, a laser created a cavitation bubble in a water droplet. When it collapsed, the bubble formed two jets &emdash; a taller, thinner jet coming up the middle of a shorter, wider jet. The small ring of bubbles inside the droplet is the remains of the initial cavitation bubble. https://www.youtube.com/watch?v=gR0YBAhY2PQ Image: Claus-Dieter Ohl/Nanyang Technological University. Video: ESA, Danail Obreschkow, Philippe Kobel, Nicolas Dorsaz, Aurèle de Bosset, Mohamed Farhat.Kelvin-Helmholtz Instability The waves in the cloud image above illustrate what happens when two flows right next to each other travel at different speeds, creating what is known as a Kelvin-Helmholtz Instability. When this occurs, the area where the two flows meet builds up friction, which rolls one layer up into vortices. Kelvin-Helmholtz instabilities show up well on planets like Saturn (below), that have alternating atmospheric bands. Images: 1) Kate Calder/Flickr. 2) NASA-JPL.Bouncing Jet Normally, when you pour a liquid into a pool of another liquid, the stream plunges right in. But if that pool is moving when the liquid hits it, the stream can actually bounce along a thin layer of air just above the pool's surface. In the image above, silicone oil is poured into a moving bath of the same liquid. When the stream hits the air layer above the pool, the weight of the stream bends the pool's surface like a rubber band — surface tension keeps the stream from punching through the top of the pool. The oil then bounces up out of the little dip it's created and arcs over the pool. https://www.youtube.com/watch?v=BVpGCy5ZdZc Image: Matthew Thrasher/University of Texas at Austin. Video: Matthew Thrasher, Sunghwan Jung, Yee Kwong Pang, Harry L. Swinney / Center for Nonlinear Dynamics, University of Texas at Austin.See Also:- Earth's Most Stunning Natural Fractal PatternsGallery: 10 Stunning Science VisualizationsGeeky Math Equation Creates Beautiful 3-D WorldJellyfish Are the Dark Energy of the Oceans


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Personality Unisex Engraved Alloy Bracelet Photo Watch 40mm
- Description
Surprise your loved one with a custom photo watch which is purely custom made to fit any personality. Add happiness to your life. The image of design is directly printed onto the inside of watch surface. Once you place an order, you'll be able to preview how it will appear on the watch. Please do remember high resolution picture will come out better than the preview. This custom photo watch cannot be refunded once we start the making process. A custom photo watch always makes a great gift and will never go out of style. Buy yours today!
- Details
ColorSilverMaterialSpecial AlloyTechnicsAnti-oxidation
- Shipping
You can choose the delivery method during checkout:
USPS First Class Shipping : $5.99 - Free U.S. shipping over $69.00
Delivery usually takes 8-10 business days
DHL Express Shipping : $16.95 - Free Over $150.00
Delivery usually takes 3-5 business days
Please note that the time frame mentioned above doesn't include production time.
over $49.00
by world's top designers
Precious Metals


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General Portrait Photography
Other Disciplines:
Art & Landscape Photography
Commercial Photography
Jenny Barker is a photographer catering for the corporate and humanitarian sector. She holds a LIPPA with the Irish Professional Photographers Association and is a member of the PPAI and the SWPP.
Her images have appeared in a variety of magazines, newspapers, brochures, websites, annual reports and fundraising campaigns.
Jenny's work includes corporate head shots, event/conference and commercial photography, and profile images for media publications.
She also specialises in humanitarian photography, working with NGO's and charities which has brought her to work on challenging projects throughout India, Haiti and Africa. She is a recent recipient of the Simon Cumbers Media Fund.
By investing in the talent and expertise of an IPPVA photographer or videographer you are insuring that careful planning goes into unobtrusively capturing the key moments, people and atmosphere of your big day.
When you engage the services of an IPPVA photographer or videographer you will be working with someone who upholds the strictest professional standards, who deals fairly and honestly with you, and who strives to create images that you will cherish for years to come.


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The REAL ID and Renewing Your MA Driver's License
March 15, 2018
UPDATE: Due to the COVID-19 pandemic,the Massachusetts RMV will not issue any REAL IDs until September 2020.
But don't worry. The Department of Homeland Security is extending the REAL ID enforcement deadline by one year. The new deadline is October 1, 2021. (This means your will still be able to board domestic flights and/or enter federal buildings with just your regular license until 10/1/21). We will keep you posted as new RMV updates emerge.
You may have heard the buzz about a new form of identification— the REAL ID —which will soon be required whenever you board a plane, including domestic flights (within the U.S.), beginning in October 2021. What do you need to know about these identification cards? How do they compare to your current MA driver's license? We've summed it up below:
What is the REAL ID?
The REAL ID is a new type of credential that the Massachusetts RMV will begin to issue on March 26, 2018. Although it is not a federal identification card, it represents a new set of federal security standards that are being adopted across the country. (After the 9/11 attacks, national leaders agreed that we needed more secure, more consistent personal identity documents.) Some states are already in compliance with these new standards and have already issued REAL ID cards to all appropriate residents. Other states, like Massachusetts, have received extensions to phase in the new standards by 2021.
In the meantime, the Massachusetts RMV has been working to upgrade its licensing software system and design new identification cards that will comply with REAL ID Act standards.
What's the difference between a REAL ID and a MA driver's license?
Going forward, the REAL ID will function as both a driver's license and a federally-compliant ID card. It will have a gold star in the upper-right corner, indicating that it is an acceptable form of identification for entering government buildings or boarding airplanes.
If you prefer, you can still apply for/renew a standard Massachusetts driver's license or ID card—even after 2021. And in fact, you may prefer to do this if you enjoy the convenience of being able to process your license online. (REAL IDs cannot be processed online; you must visit a Massachusetts RMV service center in person.) If you need to fly or enter certain government buildings after October 2021, you would need to carry your passport.
Which type of identification do I need?
The Mass RMV put together this handy quiz to help you determine if you need to get a REAL ID now, later, or never. Basically, if you have a current passport and plan to maintain it (renew when necessary), you're all set. The RMV doesn't recommend banging down the door to get your new ID card (even though technically you can apply for one).
If however you don't have a passport, and you do plan to fly, and your license is up for renewal soon, it might make sense to renew with an ID versus a traditional Massachusetts driver's license.
To sum things up: You don't need a REAL ID until October of 2021. And even then, you may not absolutely need it. In most cases it's best to wait and apply for it when your MA license/ID is due for renewal.
How do I get a REAL ID?
Applying for an ID will soon be part of the application process to renew your driver's license—either online or at the DMV. Starting on March 26, 2018, individuals applying for registry credentials will be encouraged to visit www.mass.gov/rmv and answer a few questions. The website will help you decide between:
- a REAL ID driver's license
- a REAL ID card
- a standard driver's license
- a standard MA ID card
The website will also tell you exactly which identification documents are necessary for each option. Keep in mind: starting on March 26, 2018, in order to get or renew any Massachusetts driver's license, ID card, or learner's permit, Mass residents will need to show proof of U.S. citizenship or "lawful presence" as required by federal and state law.
Do my kids need IDs?
The TSA does not currently require passengers under 18 to provide proof of identity, but their travel companion(s) would need federally-compliant ID. For international travel, passengers of all ages must present a valid passport.


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With their cars temporarily out of commission, Sandy Faulkner and Pat Sprague aren't as mobile as they'd like to be these days. Fortunately, they don't have far to travel for fresh fruits and vegetables.
Every Wednesday morning, a farmers market sets up right outside Lincoln Park Tower Apartments on Lake Avenue in Worcester. Faulkner, Sprague and other residents of the Worcester Housing Authority property just walk out the front door of the tower and do their produce shopping.
Last week, they could choose from collards, bok choy, red and golden beets, snap peas, honey, corn, tomatoes, blueberries and much more from the long tables sitting aside the main driveway of the complex.
"I think it's great," Faulkner said after buying cucumbers. "Everything is just really nice."
Since many people at the apartments are unable to go to the farm, the Regional Environmental Council brings the farm to them, as it does to residents in other areas of the city who might not have easy access to locally grown food.
The mobile farmers market, an effort of the council's Food Justice Program, is on the road Tuesdays, Wednesdays and Thursdays, through October. (REC also holds traditional, fixed-site farmers markets Mondays at Beaver Brook Park and Saturdays at Fuller Family Park on Murray Avenue.)
"It makes it a lot easier," Sprague said after shopping at the mobile market Wednesday. "I don't have to worry about going to the store, and the prices are reasonable."
The market accepts a variety of payment methods, including Electronic Benefit Transfer cards for people getting government assistance.
Using her EBT card, which qualified her for a 50 percent discount, Sprague spent $2.62 for onions, sweet corn, cauliflower and cucumbers. Last week, she paid $3.25 for a London broil steak that she bought from the Schultz Farm van, which is part of the mobile market and sells meat and eggs in addition to produce from the family farm in Rutland.
The stop at Lake Avenue was just the first of the day for the mobile market, which later visited Webster Square Towers on Main Street, Seven Hills Foundation on West Boylston Street, the Women, Infants and Children office on Chandler Street and the YWCA downtown. In all, the market makes 16 stops over three days.
After taking care of a couple of last-minute customers on Lake Avenue, Anthony Gardner, the farmers market coordinator, and Brian Monteverd, an REC food justice associate, loaded the produce into the mobile market van, a handicapped access vehicle donated by the Worcester Regional Transit Authority.
The blue van with brightly colored fruits and vegetables painted on its sides has been retrofitted for its new purpose. A wheelchair lift has been replaced with portable steps, and bins of produce snap into place on a rack on one inside wall, with cardboard boxes packed by the farms stored underneath.
For now, blasts from the vehicle's air conditioner do the cooling, but soon the van will be equipped with a freezer and a refrigeration unit powered by solar panels, funded by a grant from the U.S. Food and Drug Administration.
Even before setting up at the day's first stop, Gardner drove to Foppema's Farm in Northbridge and New Lands Farm in Sutton, an agriculture program for refugees run by Lutheran Social Services, to stock the van. The mobile market does business rain or shine, there's lots of loading and unloading and the days, which can stretch to 12 hours, are long.
Not that Gardner's complaining. As he drove the van from Lake Avenue to Main Street last week, he turned down the air conditioner so a passenger could hear and spoke enthusiastically about bringing healthy, local and affordable food into the city's less affluent neighborhoods.
Gardner, 32, a native of East St. Louis who has lived in Worcester since 2000, volunteered at the Meals on Wheels program and at the Regional Environmental Council before getting his current job at the council. He said obesity in his family and in the general population motivates him to do what he's doing.
When he arrived at Webster Square Towers, colleague Daniel Nguyen was already setting up for a cooking demonstration, during which he saut�ed collards, onion and thick-cut bacon from Schultz Farm on a single-burner propane stove.
Besides making food available, the environmental council gives out recipe cards provided by the Community Harvest Project, and shows people how to prepare what they're buying through weekly cooking demos at the mobile market and through two-hour cooking classes for which a schedule is being developed.
Many low-income residents have not had access or been able to afford fresh food, and may not know how to prepare it, according to Casey Burns, director of the council's Food Justice Program.
"It's not just access and affordability," she said of the program's mission.
For more information on the Regional Environmental Council farmers markets and mobile farmers market, visit www.recworcester.org. Burns said a schedule for cooking classes should be posted soon.


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Twenty-Six Indicted in Drug Distribution Investigation That Led to Uncovering of Massive Health Care Fraud
Twelve Pharmacists, Four Doctors, an Accountant, and a Psychologist Among Those Charged in Scheme Alleging Criminal Activity at Over 20 Pharmacies Statewide
|U.S. Attorney's Office August 02, 2011
An indictment returned by a federal grand jury in Detroit was unsealed today, charging 26 individuals for their participation in a large-scale health care fraud and drug distribution scheme, United States Attorney Barbara L. McQuade announced today. McQuade was joined in her announcement by Special Agent in Charge Robert L. Corso of the Drug Enforcement Administration, Special Agent in Charge Andrew G. Arena of the Federal Bureau of Investigation, and Lamont Pugh, Special Agent in Charge of the Inspector General of the Department of Health and Human Services.
"Health care fraud steals funds from programs designed to benefit patients, and we all pay for it," U.S. Attorney McQuade said. "Federal and state investigators have teamed up in recent months to detect and prosecute those who commit health care fraud, and we hope that the strength of our efforts will have a deterrent effect."
Robert L. Corso, Special Agent in Charge of DEA's Detroit Field Division stated, "Confronting the illegal diversion and abuse of controlled pharmaceuticals is a top priority of DEA and our law enforcement partners. Today's arrests and the allegations in the indictment bring to light one of the largest diversion conspiracies ever uncovered in the state of Michigan. The allegations against these 26 individuals, particularly of the medical professionals, are significant. These individuals abused their positions of trust and endangered the lives of countless people by illegally distributing more than 6 million doses of opiate painkillers and depressants throughout southeast Michigan and beyond. This indictment makes it clear that the DEA and our partners in law enforcement will continue to investigate and bring to justice those individuals that are responsible for the illegal distribution of prescription medicines."
FBI Special Agent in Charge Arena stated, "Health care fraud and the abuse/diversion of prescription medications are increasing criminal threats to the United States. Dishonest health care providers involved in fraudulent activities frequently exploit Medicare and Medicaid through fraudulent billing schemes which abuse tax payer's dollars. The FBI remains committed to investigating this type of fraud and bringing these individuals to justice."
"The diversion of prescription medications coupled with the fraudulent billing of Medicare creates a toxic scenario that can place a individual's health and safety at risk as well as taxpayers dollars," said Lamont Pugh III, Special Agent in Charge of the Chicago Region for the U.S. Department of Health and Human Services, Office of Inspector General. "The OIG will continue to work with our law enforcement partners to hold those who seek to harm the Medicare program accountable."
The 34-count indictment alleges that Babubhai "Bob" Patel, 49, a Canton pharmacist, was the beneficial owner and controller of some 26 pharmacies statewide (referred to in the indictment as "the Patel Pharmacies"). Babubhai Patel concealed his ownership and control over many of the Patel Pharmacies through the use of straw owners. The indictment alleges that Babubhai Patel would offer and pay kickbacks, bribes, and other inducements to physicians, in order to induce those physicians to write prescriptions for patients with Medicare, Medicaid, and private insurance, and to direct that those prescriptions be presented to one of the Patel Pharmacies for billing. In exchange for their kickbacks and inducements, the medical professionals would write prescriptions for the patients, and bill the relevant insurers for services supposedly provided to the patients, without regard to the medical necessity of those prescriptions and services. The physicians would direct the patients to fill their prescriptions at one of the Patel Pharmacies. There, according to the indictment, Babubhai Patel and his pharmacists would bill insurers, including Medicare, Medicaid, and private insurers, for dispensing the medications, despite the fact that the medications were medically unnecessary and/or never provided. Patients were recruited into the scheme by patient recruiters, who would pay kickbacks and bribes to patients in exchange for the patients' permitting the Patel Pharmacies (and the physicians associated with Patel) to bill their insurance for medications and services that were medically unnecessary and/or never provided.
The indictment further alleges a conspiracy to distribute controlled substances at the Patel pharmacies, a purpose of which was to facilitate the submission of false and fraudulent claims to Medicare, Medicaid, and private insurers in accordance with the scheme outlined above. According to the indictment, Babubhai Patel and his associates paid physicians and podiatrists associated with the scheme kickbacks and other inducements in exchange for the medical professionals writing prescriptions for controlled substances for their patients, and directing those patients to fill the prescriptions at a Patel Pharmacy. The controlled substances involved included the Schedule II drug OxyContin, the Schedule III drug Vicodin, the Schedule IV drug Xanax, and the Schedule V drug cough syrup with codeine. According to the indictment, prescriptions for these drugs were written outside the course of legitimate medical practice. Babubhai Patel and his pharmacists would then dispense the controlled drugs to patients without medical necessity. The distribution of controlled substances in this manner was intended, in part, as a kickback to the patients for agreeing to enable their insurance cards to be billed for medications purportedly dispensed at the Patel Pharmacies. The indictment also alleges that Babubhai Patel and his pharmacists dispensed controlled substances outside the scope of legitimate medical practice to patient recruiters, as a kickback for their efforts to recruit patients into the scheme.
According to the indictment, the Patel Pharmacies billed the Medicare program not less than $37.7 million for medications purportedly provided to Medicare beneficiaries over the course of the scheme (since January 2006), and not less than $20.8 million for medications purportedly provided to Medicaid beneficiaries over the course of the scheme. The indictment further alleges that since January of 2009, the Patel Pharmacies have dispensed not less than 250,000 doses of Oxycontin, not less than 4.6 million doses of Vicodin, not less than 1.5 million doses of Xanax, and not less than 6,100 pint bottles of codeine cough syrup.
In addition to Babubhai Patel, those named in the 34-count indictment were physician Paul Petre, 43, of Rochester Hills; pharmacist Dineshkmar Patel, 33, of Canton; pharmacist Anish Bhavsar, 35, of Canton; pharmacist Ashwini Sharma, 33, of Novi; pharmacist Pinakeen Patel, 32, of Sterling Heights; pharmacist Kartik Shah, 34, of Canton, pharmacist Viral Thaker, 30, of Findlay, Ohio; pharmacist Hiren Patel, 31, of Novi; pharmacist Miteshkumar Patel, 37, of Troy; pharmacist Lokeh Tayal, 35, of Canton; pharmacist Narendera Cheraku, 33, of Farmington Hills; accountant Chetan Gujarathi, 38, of Canton; business associate Arpitkumar Patel, 26, of Romulus; business associate Sumanray Raval, 54, of Farmington Hills; business associate Harpreet Sachdeva, 38, of Canton; business associate Ramesh patel, 50, of Canton; business associate Rana Naeem, 60, of Rochester Hills; podiatrist Anmy Tran, 40, of Macomb; physician Mark Greenbain, 69, of Farmington Hills; physician Mustak Vaid, 38, of Brownstown Township; psychologist and patient recruiter Sanyani Edwards, 32, of Ferndale; business associate Komal Acharya, 27, of Farmington Hills; patient recruiter Leodis Elliott, 41, of West Bloomfield; and patient recruiter LaVar Carter, 34, of Macomb.
The investigation of this case was handled by the Drug Enforcement Administration, the Federal Bureau of Investigation, and the Department of Health and Human Services Office of Inspector General. Assisting in the investigation were the United States Marshals Service, Homeland Security, Immigration and Customs Enforcement, the Michigan Attorney General's Office, the State of Michigan Department of Community Health, Gross Ile Police Department, River Rouge Police Department, Livonia Police Department, Livingston County Sheriff's Department, Dearborn Heights Police Department, and the Clinton Township Police Department. The case is being prosecuted by Assistant U.S. Attorneys John K. Neal and Wayne F. Pratt.
An indictment is only a charge and is not evidence of guilt. A defendant is entitled to a fair trial where it will be the government's burden to prove guilt beyond a reasonable doubt.


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As Judge Alito sat still and unsmiling, Democratic members of the Senate Judiciary Committee expressed strong concerns about his views on some of the most contentious legal issues of the day: the scope of presidential power in national security cases, the power of Congress to write laws affecting the states, the validity of the 1973 ruling establishing the right to an abortion, and the one-person-one-vote doctrine.
}Some Democratic senators challenged his integrity and pledged to question him vigorously in his bid to fill the Supreme Court seat being vacated by Justice Sandra Day O'Connor.
}"He has supported a level of overreaching presidential power that, frankly, most Americans find disturbing and even frightening," Senator Edward M. Kennedy, Democrat of Massachusetts, said in an opening speech that at times was reminiscent of the lacerating remarks with which he greeted Judge Robert H. Bork before that Supreme Court nomination failed in 1987.
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There are some thwarted expectations in Redbelt, David Mamet's middling, slightly baffling drama. A thoroughly honorable West L.A. jujitsu teacher named Mike Terry is played by one of the very best actors around, Chiwetel Ejiofor. As in seeing Philip Marlowe, we can tell at a glance that Terry is honest: he lives in L.A., and yet he has no money.
Through a chain of events, Terry encounters a powerful Hollywood star (Tim Allen). The star hires him as a consultant on an Iraq War movie he's shooting in the nearby desert. On the strength of this new job, Mike's wife, Sondra (Alice Braga), gets into debt.
All of this pushes Mike in the one direction where he doesn't want to go. This black-belt, whose motto is "There is always an escape," is forced into a free-style prize-fighting match he wants nothing to do with. The sinister gimmick: the fighters have to draw lots, a black or a white marble, to see whether or not a limb will be immobilized before the fight.
Richie (David Paymer), the loan shark, learns that he's out $30,000. Instead of raging about it, he clutches his stomach in panic. It must be a variation of the proverb about how if you owe a large enough amount of money, you own the bank, the bank doesn't own you. With a defaulting customer, Richie is now in trouble with his higher-ups. This clutching of the belly may be the most sensible reaction by a, er, microfinancier onscreen since Travolta's Chili in Get Shorty noted that if break your debtor's legs, how is he going to pay you off?
Similar common sense prevails in a moment where a traumatized rape victim (Emily Mortimer) is given her first lesson in self-defense. We also note some craft in the hard-bitten lines for Ricky Jay, here playing a fight promoter. The key incident in Redbelt, the story of a valuable watch, sounds like a true anecdote. (It may be something Mamet spun off from Maupassant, but it sounds plausible, like a piece of Hollywood gossip you just ache to believe.)
Mamet appears to be reaching out to an action-movie crowd. The foreign-language-training-tape quality of his dialogue doesn't seem to echo off of the plywood of the sets, as it does in some of his other films. The gears mesh—it's just that the machine as a whole doesn't work.
It seems that Mamet trained in martial arts for five years, and he has all due reverence for his teachers. He insists on the selflessness and the good hearts of such teachers. Fair enough.
Even so, Redbelt has a Chuck Norris plot, no matter how much an intelligent writer-director refines it. Mamet would have thrived in the days when movies were 60 minutes long. Shorter running times would have let him glide by the weak spots, like the baffling behavior of a dumb but decent policeman who has fewer cops looking out for him when he's in trouble than any cop you've ever seen in a movie. A shorter running time might also make up for the almost translucent thinness of the female characters.
And as always in Mamet, the women here are men, second-class. They might be promoted to men someday, if they keep up the good work.
'Redbelt' opens on Friday, May 9, at the Century CineArts at Marin, 101 Caledonia St., Sausalito. 415.331.0255.
New and upcoming film releases.
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[youtube http://www.youtube.com/watch?v=OcY-uX2Uo3A?rel=0%5D
[youtube http://www.youtube.com/watch?v=mbQLzfLFzkM?rel=0%5D
The UFC's traditional pre-event preview show returned Tuesday, and now the full episode of "Countdown to UFC 157" is available for online viewing.
The FUEL TV special previews Saturday's pay-per-view event at Honda Center in Anaheim, Calif.
Taking up the bulk of the special was a look at the historic headliner, which pits newly crowned UFC women's bantamweight champion Ronda Rousey (6-0 MMA, 0-0 UFC) against former Strikeforce title challenger Liz Carmouche (8-2 MMA, 0-0 UFC). It's the first women's bout, title fight and headliner in UFC history.
Co-headliners and light-heavyweight contenders Dan Henderson (29-8 MMA, 6-2 UFC) and Lyoto Machida (18-3 MMA, 10-3 UFC), as well as main-card bantamweights Urijah Faber (26-6 MMA, 2-2 UFC) and Ivan Menjivar (25-9 MMA, 4-1 UFC), also are featured.
Check out both segments above.
For more on UFC 157, stay tuned to the UFC Rumors section of the site.


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A Phase IIIB Study Evaluating the Effect on Serum Lipids Following a Switch to Atazanavir in HIV Infected Subjects Evidencing Virologic Suppression on Their First PI-Based Antiretroviral Therapy
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT00067782
Recruitment Status : Completed
First Posted : August 28, 2003
Last Update Posted : April 14, 2011
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
|Condition or disease
|HIV Infections
|Drug: Atazanavir (immediate switch) Drug: Atazanavir (Week 24 switch)
|Phase 3
|Study Type :
|Interventional (Clinical Trial)
|Intervention Model:
|Parallel Assignment
|None (Open Label)
|Primary Purpose:
|Study Start Date :
|December 2002
|Actual Primary Completion Date :
|March 2005
|Actual Study Completion Date :
|March 2005
|Active Comparator: 1
Drug: Atazanavir (immediate switch)
Capsules, Oral, 400mg, Once daily, 48 weeks.
Other Name: Reyataz
|Active Comparator: 2
Drug: Atazanavir (Week 24 switch)
Capsules, Oral, 400mg, Once daily, 48 weeks.
Other Name: Reyataz
- Time to virologic rebound for subjects with HIV RNA < 50 c/mL at baseline; Magnitude/ durability of increases from baseline in absolute CD4 (Time-Averaged Difference) through WK12; Mean % change from baseline in fasting LDL cholesterol at WK12.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|16 Years and older (Child, Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Key Inclusion Criteria:
- Must be on current HIV treatment regimen at least 3 to 6 months prior to study (this must be one protease inhibitor, or ritonavir-boosted protease inhibitor, and two nucleoside reverse transcriptase inhibitors) must be subject's first PI ever received
- Plasma HIV-1 RNA level < 50 c/mL within 3 to 6 months prior to study start
- Fasting LDL cholesterol > 130 mg/dL
Key Exclusion Criteria:
- WOCBP who do not use effective barrier contraception for any reason
- Women who are pregnant or breast feeding
- A life expectancy < 12 months
- Presence of a newly diagnosed HIV-related OI or any medical condition requiring acute therapy at the time of enrollment
- Cushing's Syndrome
- Uncontrolled diabetes mellitus, history of diabetic ketoacidosis or hyperosmolar syndrome
- Untreated hypothyroidism or hyperthyroidism
- Nephrotic syndrome or significant proteinuria
- Obstructive liver disease
- Active alcohol or substance abuse
- Proven or suspected acute hepatitis in the 30 days prior to study entry
- Intractable diarrhea (greater than or equal to 6 loose stools/day for at least 7 consecutive days) within 30 days prior to study start
- History of acute or chronic pancreatitis
- Inability to swallow capsules
- Presence of cardiomyopathy
- Known history of prolonged QTc interval
Any of the following:
- clinical symptoms potentially related to heart block
- heart rate < 40 bpm
- any of the following EKG abnormalities:
i) pause length > 3 seconds ii) second or third degree AV heart block iii) QTc interval > 450 msec for males iv) QTc interval > 470 msec for females
- Fasting serum triglyceride level > 750 mg/dL
Any of the following lab values within 2 weeks of starting study drug:
- serum creatinine greater to or equal to 1.5 times the upper limit of normal
- total serum lipase greater than or equal to 1.4 times the upper limit of normal
- liver transaminases greater than or equal to 3 times the upper limit of normal
- total serum bilirubin greater than or equal to 1.5 times the upper limit of normal
- Hypersensitivity to any component of the formulation of study drug
- Use of any lipid-lowering agent within 4 weeks prior or during study
- Use of a PI-containing ARV regimen prior to entry which is comprised of more than one PI
- Inclusion of an NNRTI in the PI-containing regimen
- Prisoners or subjects involuntary incarcerated for treatment of psychiatric or physical illness
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00067782
|United States, Arizona
|Local Institution
|Phoenix, Arizona, United States
|United States, California
|Local Institution
|West Hollywood, California, United States
|United States, District of Columbia
|Local Institution
|Washington, District of Columbia, United States
|United States, Florida
|Local Institution
|Altamonte Springs, Florida, United States
|Local Institution
|Ft. Lauderdale, Florida, United States
|Local Institution
|Miami, Florida, United States
|Local Institution
|Tampa, Florida, United States
|United States, Massachusetts
|Local Institution
|Boston, Massachusetts, United States
|United States, Minnesota
|Local Institution
|Minneapolis, Minnesota, United States
|United States, Missouri
|Local Institution
|St. Louis, Missouri, United States
|United States, New Jersey
|Local Institution
|East Orange, New Jersey, United States
|United States, New York
|Local Institution
|New York, New York, United States
|United States, North Carolina
|Local Institution
|Huntersville, North Carolina, United States
|United States, Ohio
|Local Institution
|Cleveland, Ohio, United States
|United States, Oklahoma
|Local Institution
|Oklahoma City, Oklahoma, United States
|United States, Pennsylvania
|Local Institution
|Philadelphia, Pennsylvania, United States
|United States, South Carolina
|Local Institution
|Columbia, South Carolina, United States
|United States, Texas
|Local Institution
|Fort Worth, Texas, United States
|Local Institution
|Houston, Texas, United States
|Study Director:
|Bristol-Myers Squibb
|Bristol-Myers Squibb
|ClinicalTrials.gov Identifier:
|Other Study ID Numbers:
|First Posted:
|August 28, 2003 Key Record Dates
|Last Update Posted:
|April 14, 2011
|Last Verified:
|January 2010
Treatment Experienced
HIV Infections
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
Atazanavir Sulfate
HIV Protease Inhibitors
Protease Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Anti-HIV Agents
Anti-Retroviral Agents
Antiviral Agents
Anti-Infective Agents


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Johnny's Auto & Marine Electric Service means quality work. We take pride in everything we do. We can also service your marine electric system! Location: 1573 Mechanical Blvd, Garner, NC 27529 Phone: (919) 661-1553 When you need auto electric service, who do you call? Your electrical system is more than just your battery, and as computerized controls are installed in more vehicles, and becoming more important to those vehicles, it's never been more important to ensure that your auto electric system is in peak condition. Small voltage fluctuations today could be a crisis on the road tomorrow. If you need any sort of electric service on your vehicle, we urge you to call us today. View all posts by Johnnys Auto and Marine Electric