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Also known as: ABT-378
Background and Description
On September 15, 2000, the US Food and Drug Administration (FDA) granted Abbott Laboratories accelerated approval for the marketing of Kaletra. This combination product contains 2 protease inhibitors (PIs): lopinavir and Norvir (ritonavir); however, the antiviral activity of Kaletra is mainly because of the lopinavir. The addition of Norvir boosts levels of lopinavir in the blood. A tablet formulation was approved by FDA in October 2005, replacing the capsule formulation by March 2006.
Kaletra can be taken either once or twice a day, depending on a patient's situation. Once-daily dosing of Kaletra is an option only for patients who have never before taken PIs, otherwise Kaletra must be taken twice daily. The levels of Kaletra with this once-daily dose are only 60% of the twice-daily dosing, and patients reported more side effects such as diarrhea than with the twice-daily dose.
Kaletra tablets are dosed as either 2 tablets twice daily, or 4 tablets once daily. If taken by capsule, the correct dose of Kaletra is 3 capsules twice daily, or 6 capsules once daily. If taken by solution, the correct dose is 5 mL twice daily, for a total of 10 mL a day. When Kaletra is combined with either Sustiva (efavirenz) or Viramune (nevirapine) in treatment-experienced patients, once-daily dosing is not possible and the correct dose is 3 tablets twice daily, 4 capsules twice daily, or 6.5 mL of solution twice daily.
Food Restrictions
Kaletra tablets can be taken with or without food. Kaletra capsules should be taken with a meal or snack.
Kaletra tablets do not need refrigeration. Both the capsules and solution should be refrigerated at 36°F to 46°F, but both formulations can be kept at a room temperature of up to 77°F if used within 2 months.
Patient Assistance
Abbott Laboratories offers a patient assistance program for Kaletra. For more information, call 800.222.6885 (option 1).
Side Effects
The side effects most commonly associated with Kaletra are nausea and diarrhea. The most common laboratory abnormalities are increases in some tests of liver function, as well as increases in triglycerides and total cholesterol. Patients with liver impairment should use Kaletra with caution. Elevated triglycerides are associated with a risk of developing pancreatitis. Of note, during clinical trials of Kaletra, approximately 1 in 4 treatment experienced patients saw a serious or life-threatening laboratory abnormality. A small number of patients taking Kaletra may experience a severe skin rash ("Stevens Johnson Syndrome") and should see a healthcare provider immediately if any suspicious rash should appear. As a class, PIs are associated with metabolic (mainly sugar and lipid) and morphologic (body shape) changes, including the development or worsening of diabetes.
Drug Interactions
Kaletra is metabolized in the liver by cytochrome P450 (CYP3A isoform). Other drugs that are metabolized by the same pathway (but not CYP2D6) should not be taken if with Kaletra. These drugs are: Hismanal (astemizole), Seldane (terfenadine), any ergot derivative (e.g. dihydroergotamine or DHE), Propulsid (cisapride), Orap (pimozide), Versed (midazolam), Halcion (triazolam), Voriconazole (VFEND), Mevacor (lovastatin), Zocor (simvastatin), Dilantin (phenytoin), fluticasone (an ingredient in Flonase), and St. John's wort (Hypericum perforatum).
When co-administered with Kaletra, dose reductions are required for Viagra (sildenafil), Cialis (tadalafil), and Levitra (vardenafil). HIV-infected women who are taking estrogen-based contraceptives should use additional or alternative contraceptives while on Kaletra. Important interactions between Kaletra and other agents, including Rifadin or Rimactane (rifampin), Mycobutin (rifabutin), Antabuse (disulfiram), Flagyl (metronidazole), methadone, Desyrel (trazodone), alfuzosin (for prostate problems), and corticosteroids, may require adjusted dosing of either drug.
Kaletra has the potential to reduce the plasma concentrations of Retrovir and Ziagen (also contained in Trizivir); however, the clinical significance of those reductions, if any, is unknown. When Kaletra and Videx are combined, Videx should be taken 1 hour before or 2 hours after Kaletra. Kaletra increases levels of Viread, so patients taking this combination should be monitored closely for Viread-related side effects. Because Kaletra contains Norvir, other protease inhibitors will require dose adjusting if given with Kaletra. Viracept doses should be decreased and Kaletra increased if given together. Finally, Kaletra should not be taken with Agenerase or Lexiva.
Additional Information
Resistance and Cross-Resistance
Genomic point mutations associated with resistance to lopinavir/ritonavir have not yet been identified; however, isolates with reduced susceptibility to Kaletra have been selected both in vitro and in vivo.
The relevance of resistance to other protease inhibitors (PIs) on the virologic success of Kaletra has not yet been fully characterized. In a study of 56 patients who had been treated with at least 2 other PIs, a Kaletra-containing regimen suppressed viral load below the limits of quantification (400 copies/mL) in 24 of 25 patients whose baseline virus contained 5 point mutations associated with resistance to PI therapy. However, these 25 patients, all of whom were naive to non-nucleoside reverse transcriptase inhibitors (NNRTIs), were given Sustiva, a potent NNRTI, in addition to Kaletra and nucleoside reverse transcriptase inhibitors (NRTIs). Therefore, it is difficult to assess the relative contribution of Kaletra to the virologic success experienced by the patients in that study.
Clinical Data in Treatment-Naive Patients
Study 863 is a double-blind trial in which investigators randomized 653 treatment-naive patients to a regimen of Kaletra/Zerit/Epivir or Viracept/Zerit/Epivir. The participants, mostly Caucasian males, had an average baseline CD4 T cell count of 259 cells/mm3 and an average baseline viral load of approximately 79,000 copies/mL. After 24 weeks, 79% of participants in the Kaletra arm had viral loads less than 400 copies/mL, with 65% having viral loads less than 50 copies/mL. Participants saw an average CD4 T cell increase of 154 cells/mm3.
Importantly, 3 patients in the Kaletra arm and 3 patients in the Viracept arm experienced new AIDS-defining clinical events despite having viral loads below the limit of quantification. These data demonstrate that while a reduction in viral load greatly reduces the risk of disease progression on a population basis, even an unquantifiable viral load does not preclude the occurrence of AIDS-defining events in the individual.
Clinical Data in Treatment-Experienced Patients
Study 765 is a randomized, blinded trial using 2 doses of Kaletra, namely 400 mg of lopinavir and 100 mg of ritonavir or 400 mg of lopinavir and 200 mg of ritonavir. The participants, all of whom had taken 1 prior protease inhibitor but were naive to NNRTIs, also took the NNRTI Viramune plus 2 NRTIs. The study volunteers were mostly Caucasian males with an average baseline CD4 T cell count of 372 cells/mm3 and an average baseline viral load of approximately 10,000 copies/mL.
After 72 weeks of treatment, 75% of volunteers in the 400 mg/100 mg arm had viral loads less than 400 copies/mL, with 58% having viral loads less than 50 copies/mL. The average CD4 T cell increase was 174 cells/mm3.


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It's here – the much-anticipated weekend of July 4th, 2011! It's a weekend to entertain or be entertained. My homage to the birth of America is to celebrate with an all-American do-ahead menu. To begin, start with chips and dips of your choice.
Red, white and blue potato salad laden with fresh herbs and a tasty vinaigrette can be prepared up to a day ahead. Traditional American summertime favorites include burgers and ribs on the grill. If it's burgers for the Fourth, season them with finely chopped shallots, a tablespoon of Worcestershire sauce for a pound of ground chuck, salt, pepper and a splash of cream – yummy with sautéed onions and a dollop of ketchup. For long and slow-cooked ribs on the grill I turn to Steven Raichlen's The Barbecue Bible (Workman, 1998), for his baby back ribs. Memphis style. Unless you're a barbecue guru I highly recommend that you reference Raichlen's techniques for foolproof grilling. Quench your thirst with ice tea and/or local beers from Southampton Publick House.
Chilled watermelon to cool and clear the palate is always welcome, but take the sweet ending to another level with a parfait of white chocolate mousse and fresh local berries. And have a Happy Fourth!
Yield: about 8 cups or 10 to 12 servings
2 1/2 pounds white, red and blue fingerling potatoes or an equal mix of Yukon gold, new
red and purple potatoes, scrubbed clean
Kosher salt
2 to 3 tablespoons dry white wine
1/2 cup diced red onion
2 teaspoons grainy Dijon mustard
3 tablespoons red wine vinegar
3 tablespoons extra-virgin olive oil
1/2 cup chopped flat-leaf Italian parsley
1/2 cup thinly sliced fresh chives
1. Place the potatoes in a large saucepan and cover with cold water by and inch or two. Cover pan and bring to a boil over high heat; stir about 1 tablespoon salt into the water. Adjust heat to medium-high and cook the potatoes at a brisk simmer for 16 to 18 minutes until tender when pierced with a knife. Drain in a colander and transfer to a large mixing bowl. Sprinkle with white wine and toss gently to mix. With fork and sharp knife cut the potatoes into bite-size pieces (I do this right in the bowl).
2. Meanwhile soak the onion in cold water in a small bowl for about 20 minutes (this softens the "bite" of the onion). Drain and dry in a clean kitchen towel. Add diced onion to the potatoes.
3. Whisk the Dijon mustard, red wine vinegar and olive oil in a separate bowl and add herbs, salt and pepper to taste. Scrape the dressing into the potato mixture and stir gently to mix with a rubber spatula. Taste for seasoning and transfer to a covered container; refrigerate. Can be prepared up to one day ahead. Bring to room temperature and taste for seasoning before serving.
Steven Raichlen wrote the ultimate cookbook on barbecue!
Serves 6 to 8
4 to 6 pounds baby back ribs
1/4 cup paprika
1 1/2 tablespoons freshly ground pepper
1 1/2 tablespoons firmly packed dark brown sugar
1 tablespoon kosher salt
1 1/2 teaspoon each celery salt, cayenne, garlic powder, dry mustard, ground cumin
1. Remove the thin papery skin from the back of the ribs by pulling it off in a sheet with your fingers, using the corner of a kitchen towel to gain a secure grip, or with pliers. Combine the ingredients for the rub in a small bowl and stir to mix. Rub two thirds of this mixture on both sides of the ribs, transfer to a Pyrex (lasagna-size) dish, cover and refrigerate for 4 to 8 hours.
2. Set up grill for indirect grilling by placing a large drip pan on the bottom center grate. Place charcoal or wood chips in the bottom of a chimney starter (most favored by grill buffs) and pile a few sheets of crumpled newspaper on top. Place the chimney on the upper grate. Touch a lit match to the paper and soon the coals will be blazing. When the coals are ready – this could take about 20 minutes – lift the chimney and dump out the coals on either side of the drip pan. Place the food on the grate. If using a charcoal grill, preheat to medium. If using a gas grill, pre-heat grill to high: when smoke appears, reduce the heat to medium.
3. If using wood chips such as hickory or mesquite presoak chips in a smoker box (for gas) or aluminum loaf pan (for charcoal) for 20 minutes, then place over the ashen coals. For charcoal preheat grill to medium and toss half the wood chips on the coals. For gas, preheat grill to high: when smoke appears, reduce heat to medium.
4. Arrange ribs on the hot grate over the drip pan or unheated side if gas. Cover the grill and smoke-cook the ribs for 1 hour.
5. Toss remaining chips on the fire if using charcoal or wood chips. Continue cooking the ribs until tender and almost done, about 1/2 to 1 hour longer for baby back ribs, somewhat longer for spareribs. If using charcoal, keep adding a few coals to the side of the grill until meat is completely tender and has shrunk back from the ends of the bones. Transfer to a cutting board and slice between the ribs for serving.
The Fourth of July means picnics, parties and tasty treats. If parfait glasses are not available
simply top the berries with the creamy white chocolate mousse.
Serves 6
3 to 3 1/2 ounces fine quality white chocolate
1/2 cup thick crème fraîche
2 tablespoons sugar
1 cup fresh strawberries, hulled and rinsed
1 cup fresh blueberries, rinsed
Grated rind of 1 lemon
1 to 2 teaspoons brandy, optional
Extra whole strawberries for garnish
1. Break up the chocolate into small pieces and put into a mixing bowl large enough to straddle a saucepan. Put about 1/4 cup water in the saucepan and place the bowl with the chocolate over the pan. Place over low heat to melt the chocolate. Watch carefully as chocolate melts, then stir to a smooth cream. Remove from heat and let cool completely.
2. Whip the crème fraîche with the sugar until fluffy. Add the cooled chocolate in a thin steady stream whisking until smooth.
3. Slice the strawberries and mix with the blueberries. Add lemon rind and brandy, if using, and gently stir to mix. To assemble the parfaits, alternately layer the mousse with the mixed berries in parfait glasses or top berries with the mousse. Garnish with whole strawberries, if desired.

subset: commoncrawl


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A former conservative official has rallied 400 economists, including five Nobel Prize winners, to sign a statement supporting Republican presidential hopeful Mitt Romney's economic policies.
Nobel Prize-winning economists Gary Becker, Robert Lucas, Robert Mundell, Edward Prescott and Myron Scholes are among the names listed on the website, Economists for Romney.
The site's founder, James Carter, was a deputy assistant Treasury secretary of former President George W. Bush. Economists for Romney describes itself as "an independent, voluntary association of economists" supporting the former Massachusetts governor and says it "is not an official arm of the 2012 Mitt Romney campaign."
AdvisorOne could find no comparable list of economists supporting President Obama, though the prominent liberal economist Brad DeLong derided the list on his blog, suggesting its signers should "back out" now that Romney has chosen Rep. Paul Ryan, R-Wis., as his running mate. DeLong also said 400 was not a high number in comparison to the more than 1,000 economists who Republican presidents have appointed to positions on the Council of Economic Advisers.
The list is reminiscent of the support Obama received in his first presidential run, when six Nobel Prize-winning economists and others including DeLong, a professor at the University of California, Berkeley, supported the president. The Nobel winners included Paul Krugman, Daniel McFadden, Edmund Phelps, Amartya Sen, Robert Solow and Joseph Stiglitz.
It is not clear how many of these economists still count themselves as Obama supporters. The Obama campaign has yet to respond to a request from AdvisorOne for a list of current supporters among economists.
The statement signed by the group said the governor's economic plan was based on "a more contained and less intrusive federal government, a greater reliance on the private sector, a broad expansion of opportunity without government favors for special interests, and respect for the rule of law including the decision-making authority of states and localities."
Among the specific policies the economists endorsed, they said, are Romney's plan to reduce marginal tax rates and thereby broaden the tax base, ensure that federal spending not exceed 20% of GDP, and restructure regulation so as to end "too big to fail."
The economists blasted Obama for "increasing the size and scope of the federal government, which increases the debt, requires large tax increases, and burdens business with many new financial and health care regulations."
Prominent names among the signatories are Robert Barro (Harvard), Michael Boskin (Stanford), Martin Feldstein (Harvard), Allan Meltzer (Carnegie Mellon) and John Taylor (Stanford).
Big names in the business world on record as supporting Obama in 2012 include former Microsoft CEO Bill Gates and Warren Buffett, the chairman and CEO of Berkshire Hathaway. The Omaha businessman told Fox News in May he supported the president "100%."
As for Obama's 2008 economist supporters, Paul Krugman's most recent blog posts make clear he vociferously opposes the Republican ticket. Columbia University professor Joseph Stiglitz expressed criticism of both Obama and Romney in his most recent New York Times op-ed on U.S. housing policy.


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Scientists have painstakingly measured 2.7 billion-year-old raindrop fossils from South Africa. The size of the ancient droplets tells the story of how the earth was teeming with microbes when it should have been frozen solid.
Between two and four billion years ago, the sun was 30 per cent dimmer than it is today, so really, the earth should have been frozen solid. But we have evidence of rivers and ocean sediments from back then, so something was making the planet warm. The ancient raindrops revealed that it was greenhouse gases — they increased atmospheric pressure, heating up our world.
Here's how the researchers figured all that out.
Hairspray, Latex and Stairwells
A scientist can't just use a barometer to measure the atmospheric pressure of a fossilized droplet. Instead, Roger Buick and Jelte Harnmeijer poured latex over the 2.7 billion-year-old raindrop impressions, which were petrified in volcanic ash found in South Africa. They shipped the latex peels to their lab at the University of Washington in Seattle. There, a high-precision laser scanner measured the droplets.
The size of raindrop impressions gets larger as the velocity of the droplet increases. Higher atmospheric pressure will slow that velocity. The composition of material onto which the raindrops fall also effects the size of the droplets. Previous research showed that raindrops on earth don't exceed a quarter inch in diameter, so the researchers figured that was the largest any of the ancient raindrops could have been, regardless of atmospheric pressure.
In today's atmosphere, the largest raindrops fall at about 9 metres per second. But if the ancient atmosphere was thicker, the speed would have been lower, and the maximum size of imprints left behind would be smaller.
To create a present-day comparison, two other researchers released water droplets of varying sizes 27 metres down an open stairwell onto volcanic ash collected from Hawaii and Iceland. Sanjay Som, lead author on the study, worked with Peter Polivka to coat the raindrop sculptures with liquid plastic and hair spray. This kept the ash molds intact, and then the laser could scan the impressions.
Comparing the two showed that, if the biggest imprints were formed by the largest raindrops, the atmospheric pressure 2.7 billion years ago could have been no more than twice what it is today. And since the largest raindrops were actually few and far between, the pressure was probably the same, or possibly lower. Without a hot sun to create the pressure and heat, they concluded, a buildup of greenhouse gases in the atmosphere was keeping Earth toasty.
Life on Other Planets
If atmospheric pressure allowed life on a planet that should have been frozen, Som said in a statement, scientists could better estimate the probability of life on the exoplanets currently being discovered.
Setting limits on atmospheric pressure is the first step towards understanding what the atmospheric composition was then. Knowing this will double the known data points that we have for comparison to exoplanets that might support life. Today's Earth and the ancient Earth are like two different planets.
Sometimes it sounds really freaking fun to be a scientist. The raindrop fossil test results appear in the March 28 issue of Nature. [Nature]
Image: NASA


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There's nothing in HMRC guidelines that says a company car can't be a hoot to drive. Which is good, because a MINI makes brilliant sense for your business. For one thing, MINI achieves exceptional residual values, so running a MINI for your business is cheaper than you might think.


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Old Home Day
1638 - Town of Hampton - 1961
32 Mill Road
This house is a charming example of early nineteenth century Cape Cod construction. It was built by David Marston Leavitt at about 1830. For some unknown reason, Mr. Leavitt later exchanged this property with David Jonathan Garland who had built a house on Winnacunnet Road. For many years this branch of the Garland family lived in the house.
Several families have lived here in the twentieth century. Some Hamptonites remember taking piano lessons in the house when it was occupied by the Gookin family. People of a later generation recall pursuing art lessons in David Leavitt's shop when the Wholleys (Janice Newton [Wholley] Naves) lived in the house.
This old house has many unusual features for the visitor to see. An old fashioned bulkhead entrance to what was a little shop with a fireplace in the cellar gives credence to the story that the cellar room was once used by Mr. Leavitt as a cobbler's shop. Although Mr. Leavitt was a carpenter by trade, it is possible that he carried on the shoe-maker's craft between carpentry jobs.
The paneling around the fireplaces on the first floor of this house is of special significance to Hampton because it was taken from the ends of the old square pews in the fifth Meeting House erected in 1796. Visitors will also find interesting, the so-called "hate room" at the top of the stairs leading from the side of "funeral" entrance. The designation of this as the "hate room" derives from the fact that unless one was extremely wary and stooped low, the very low ceiling would give him a vigorous bump on the head, presumably knocking from his consciousness whatever hate he might be harboring. In the pantry of this house may be seen the old brick oven and laundry sink, those necessary utilitarian adjuncts to the living in the early nineteenth century.
In 1957, this house was purchased by the Misses Helen and Gertrude Clifford of Boston as a summer home and week-end retreat. The Cliffords plan to make this place their permanent home some time in the future.


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Benjamin Gibbard - Words and Music - 2012
12.06.12 1:15pm
You'd think Benjamin Gibbard would have enough on his plate fronting Death Cab for Cutie, but beyond his additional side projects, he's also had a solo career simmering away for awhile. This year, he released his first full-length album purely under his own name, and it's called Former Lives. Check out a couple of the songs performed live during my conversation with Benjamin—which included some baseball talk too.
[recorded: 10/18/12]
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Sunday is Mother's Day. You're welcome for the reminder you thoughtless prick.
I've still got Chloe Moretz fever. I say still because I'm pretty sure I've used this joke before and I know you jag-offs at home are keeping score so I wanted to play it safe. The news here though is that Moretz is in talks with Inferno Entertainment to play a zombie in their new film "Maggie". The film follows Maggie's 6 month transformation into a zombie and will be awesome. Unless Dakota Fanning somehow ends up playing the role. That would blow.
You had me at "From the producer of 'The Crow'". That's sarcasm by the way, I don't want you to ever mistake my sarcasm as love for "The Crow". When I was in High School I was on the football team and there was this prick Marty who painted his face like the Crow before a game. I will hate that kid till the day I die for that reason alone. Well his odd passion for country music too but mostly the crow thing. My point is Edward R. Pressman is working on an adaptation of the graphic novel "Feeding Ground".
"'The Raid' WILL EXPLODE IN OVER 280 CINEMAS ACROSS THE UK & IRELAND ON 18 MAY". I don't care how old I get saying something will "explode" will always make me chuckle. Think about it. Ya know... like when a man... NEVERMIND! But the rumors are true, the little movie that could about a lone cop left standing after a drug raid will be hitting selected theaters this month for your viewing pleasure. Unless of course you're in the US. Then you get no pleasure.
The guys who wrote a bunch of those "Not Another..." movies are now writing a spoof of "The Hunger Games" called "The Starving Games". I don't think I can do this anymore.
Here's a story about a group of 6th grade boys down in Mexico that made a gay porn in one of their classrooms. Congratulations Mexico, you're come up with the most disturbing story I've ever read.
A Florida man, I know shocking, decided to stab his computer with a Samurai sword as police raided is house looking for child pornography. Yes there's no way that this will erase anything from his hard drive but you got to admire his style. Ya know, as much as you can admire a guy who's downloading kiddie porn.


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Alaska State Troopers say a 57-year-old woman drove herself to a hospital after she was mauled by a brown bear.
Troopers were notified yesterday afternoon that Thea Thomas of Cordova was attacked by the bear while hiking on Heney Ridge Trail in the Cordova area.
Salmon were actively spawning in a nearby stream as Thomas hiked with two dogs. The dogs ran off, then returned shortly with the bear running after them.
Troopers say the bear noticed Thomas and attacked her multiple times. The dogs took off again.
After the attack, Thomas walked one and a half miles back to her truck. She found one of the dogs while walking back and the other dog was waiting at her vehicle.
Troopers say the trail is now closed for a week.


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Body Art
Body art is very broad term which includes ear piercing to a funky tattoo, painting or you can say everything related to skin decoration. Today there is a craze among college students especially to get a funky tattoo done. Having a body art done is a means to express themselves and their individuality.
Besides piercing and tattooing body painting is growing in popularity as a body art form. Body art painting treats human body as a blank canvas, and beautiful crafty colorful pictures are drawn on it. Although this artistry may not be your drawing room's show case they are still splendid.
These days companies have employed a new marketing funda of using body painting as a form of advertising. Many advertisements showcase the models with company logos painted onto their bodies.
Be it a sports day at school or cricket match in the country or going in discs beautiful body art, or painting is apparent. Fans many times express their love and compassion for their favorite team by painting the team mascot or writing their favorite team's name.
Tattoo as the popular body art
Tattoos are very old art, anciently practiced as marking to identify animals or some convicts and also as permanent ornaments to decorate the body. The word Tattoo is actually derived from a Tahitian word "Tatau." The regularly growing passion Tattoos differ in patterns between males and females. Where males prefer tribal, skull, scorpion patterns, females go for angel, sun, moon patterns.
Tattoos may be permanent or temporary. Heena or mehandi, sticker tattoo or that drawn from water colors is temporary tattoos. Permanent tattoos are much painful and costly too. Inspite of pain involved tattooing has been practiced by modern as well as tribes across the world. The procedure of making tattoos too sports a wide variety; in some cultures tattoos are formed from scaring and rubbing it with ashes or charring while pricking with thorns to insert dyes in others.
Uses of Tattoo
1. Decorative and spiritual uses of tattoos involve symbols of religious and spiritual devotion, decorations for bravery, mark of fertility, amulets and talismans for protection.
2. Now-a-days people choose to be tattooed for cosmetic and sentimental purposes. Extensive decorative tattooing is common for traditional freak shows and by performers who follow in their tradition.
3. Tattoos are a marking that gives an idea about status and rank of an individual.
4. The tattoos were carved out for identification of inmates by Nazis. Sometime a tattoo can be useful for forensic pathologists as they might help identify burned or mutilated bodies.
5. These days for the cosmetic purpose tattoos are marked as permanent eyebrows, lips liner or lipstick, eye liner and even moles.
6. A new application of tattoo is 'Medical tattoos.' Tattoos are used for in repeated radiotherapy and for breast reconstruction.
Method of Tattooing
Modern days tattoo parlors mushrooming in cities uses the electric tattoo machine which has an oscillating unit that has a mount of group of needles. These needles dipped in Azo- or Acri- dyes goes in and out of the skin around 80-150 times resulting into a gorgeous tattoo.
So, be sure to do some research and think about the pains before GAIN….
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CASCADE, Idaho (AP) – The FBI says it's sending a team to Idaho to investigate the shooting that led to the death of a man suspected of killing a California woman and her young son and abducting her 16-year-old daughter.
Forty-year-old James Lee DiMaggio was killed Saturday after his campsite was spotted in Idaho's rugged Frank Church River of No Return Wilderness.
The teen, Hannah Anderson, was found safe. Ada County sheriff's spokeswoman Andrea Dearden says she has no apparent injuries and there are no reports of injuries among law enforcement.
At a news conference Saturday evening, Dearden said the teen and DiMaggio were spotted not far from where a horseback rider reported seeing the pair Wednesday.
Dearden said she didn't know if DiMaggio fired at officers.
Authorities offered few other details as the team from Washington, D.C., prepares to investigate.


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With over 5 million users EpocCam is the most popular webcam app. EpocCam transforms your iOS device into wireless High Definition PC webcam for Windows and macOS. Replace your USB-webcam and integrated webcams now with wireless high-definition webcam. It's also a perfect baby monitor, spycam, security camera and pet cam. Setting up EpocCam is very simple, anyone can do it. Just download EpocCam drivers for free to your PC/Mac and you're ready to go! Connection is fully automatic, no need for manual setup. Features: • High quality realtime video streaming to computer - quality comparable to most expensive USB-webcams • Support both cameras - use device back camera for best quality and front-facing camera for easy self-portraits • Fully replaces USB webcam or integrated webcam, works with all webcam-enabled applications • Full Windows 10 support including Skype • Automatic connectivity • Over 20 feet wireless range (depending on signal strength) • All data is secured with strong encryption to keep your videos private • Use the flashlight in dark environment • Tap to focus and autofocus modes • Audio support, use your phone as a wireless microphone* • Publish video to Syphon framework on Mac - use EpocCam as source to Isadora, Modul8, GrandVJ and other applications *Available for Windows. Mac version is coming soon. Requirements: - iOS device running iOS 10.3 or later - Computer running Windows 7 or later or Mac running macOS 10.10 or later - WiFi network, 5 GHz WiFi recommended See http://www.kinoni.com/epoccam_support.html for setup guide.
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This was published 7 years ago
Fresh hope for life on watery world
Hot on the heels of NASA's recent announcement that the subsurface ocean on Jupiter's moon Europa is one of the solar system's likeliest bets for alien life is more food for thought.
Saturn's giant moon Titan, larger than the planet Mercury, is also home to a subsurface ocean — only this one seems likely to contain as much liquid as all the world's oceans combined.
Earlier this week, NASA's Saturn-orbiting spacecraft, Cassini, swooped low across Titan's surface, making crucial gravity measurements. (A better understanding of the moon's gravity will reveal more about the size and composition of its subsurface sea.)
At its closest approach, the Cassini probe flew within 1978 kilometres of the distant moon's icy surface.
Although it is too soon to be certain of exactly what the ocean consists of, astrophysicists can hazard a shrewd guess. "The data will take months to analyse," says Cornell University astronomer Jonathan Lunine. "But we can be very certain from past flybys that there is a liquid layer underlying the crust of Titan."
Dr Lunine is part of a team of scientists, led by Luciano Iess of Italy's Sapienza University, who previously studied how Titan's gravity and shape alter as the giant moon orbits its parent planet.
After calculating the likely properties of an ocean below the thick icy crust of Titan, the team was convinced that the subsurface ocean is predominantly liquid water. If true, this would offer the chance of finding extraterrestrial life.
"Solutes like ammonia will lower the density a bit, while sulphur will raise it," Professor Lunine explains. "But it isn't a layer of liquid methane — the density would be too low to account for the observed gravity data. And the overlying water ice crust would, in any event, founder if it were atop liquid methane."
It is not yet possible to peer into inside Titan, reminds CSIRO astrophysicist Kurt Liffman. So the presence of a liquid ocean is based on models of the interior. "Measurements of Titan's shape as the moon travels around Saturn can be compared with predictions from different models," Dr Liffman notes.
Other ingredients
Some scientists believe that, in addition to vast quantities of water, Titan's ocean might also contain ammonia and perhaps a little methane.
"Based on the estimated abundances of nitrogen, hydrogen and carbon, plus the expected temperatures and pressures in the Saturnian region of the disc of gas and dust that surrounded the early sun, it is reasonable to expect the presence of ammonia and perhaps methane within Titan," Dr Liffman says.
In the view of Monash University astrophysicist Andrew Prentice, the subsurface ocean most likely consists of pure methane and beneath that a layer of ammonia ice that is quite soft.
"My model predicts a fairly thin layer of liquid methane about six kilometres deep and located 50 kilometres below Titan's outer solid crust of water-ice," Dr Prentice explains. "Beneath the liquid layer there is probably a 14-kilometre-thick layer of soft ammonia ice."
It would be very tough for any life form to survive in a subsurface ocean since there is so little sunlight that reaches the surface, Dr Prentice says. "Titan's source of internal heat through the decay of short lived radio nuclides is also very tiny."
By contrast, Jupiter's large Galilean moon Europa has a greater chance of harbouring life forms, most scientists believe.
Titan revealed
Discovered in 1655 by Christiaan Huygens, Titan — covered in an orange haze of cloud, morning mist and naturally produced photochemical smog – has been scrutinised by telescopes and, more recently, by spacecraft.
In 2004, a small NASA probe called Huygens separated from its mother craft, Cassini. After several weeks, the probe parachuted down to Titan's surface and, for several hours, relayed close-up images to Earth.
"The Huygens probe imaged channels, but its descent through the atmosphere was at low latitudes and so it didn't detect any lakes," says Elizabeth Turtle of Johns Hopkins University's Applied Physics Laboratory in the US.
Since then, scientists have deduced that beneath the moon's clouds lurk large lakes, some spanning thousands of square kilometres. That would make them roughly the size of the Black Sea or Caspian Sea; one is thought to be bigger than Lake Superior, the world's largest freshwater lake by surface area.
"The lakes and seas are found at high latitudes and predominantly in the northern hemisphere, although there are some near the southern pole," Dr Turtle adds.
"There appear to be no permanent bodies of liquid at equatorial latitudes. However, there was once a large rainstorm over low latitudes and there may still be some areas of ponded runoff — although they've been receding."
Titan has seasons, says Candy Hansen, Cassini scientist at NASA's Jet Propulsion Laboratory in Pasadena, California.
"That's partly why there are more lakes right now in the northern hemisphere, and why some lakes are evaporating," Dr Hansen explains. "These seasonal changes occurred as the sun has moved from the southern to the northern hemisphere in the last eight years that Cassini has been exploring Titan."
The differences between the northern and southern summers are also caused by Saturn's orbital eccentricity and possibly longer-term orbital variations, she adds.
Frozen solid
Titan is in a state of deep freeze, with surface temperatures averaging about minus 180 degrees. If the lakes contained water they would be frozen solid. But these lakes hold liquid hydrocarbons, mainly ethane and some methane, that freeze at much lower temperatures than water.
The remote moon has something resembling Earth's water cycle, with surface liquids evaporating and returning as rain. But on Titan, it rains ethane and methane — not water — the only moon in our solar system to have such a cycle.
At Titan's South Pole, the Cassini orbiter once detected fog, caused by surface methane evaporating and then condensing into humid air.
Other likely surface features include wandering streams and riverbeds, probably carved by liquid ethane, beaches — that get more exposed as the lakes they border slowly evaporate — plains, ancient craters and volcanoes, though probably not active ones.
Weirder than weird
Is it feasible for life to exist in Titan's liquid ethane lakes? Weird life maybe, suggests Dr Prentice. But even the hardiest of microbes would struggle to tough it out, he says.
Titan appeals to life scientists, in part, because its planet-like atmosphere is denser than that of Mercury, Earth, Mars or Pluto. It is, in fact, the solar system's only moon with a thick atmosphere and a pressure about 50 per cent higher than that at sea level on Earth.
Its atmosphere consists mainly of nitrogen, the Earth's main gas — as well as hydrogen. (Some pundits say it might be similar to what the atmosphere was like here many eons ago.)
Titan is also the only place in the solar system, apart from Earth, to have liquid both on and beneath its surface.
Cassini's next flyby of Titan will be April 5, at 1400 kilometres, followed by another on May 23 at 970 kilometres. Stay tuned for more unearthly surprises.
- Please send bright ideas for new science topics to email@example.com
Daniel Hurst covers federal politics, focusing on education, employment and workplace relations.


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Nokia has been hit with a class-action lawsuit for failing to turn around its smartphone business in six months and reporting substantial losses for the first quarter of this year.
Investor Robert Chmielinski says that between October 11th, 2011, and April 10th, 2012, Nokia engaged in fraud. Over that period Nokia CEO Stephen Elop made a number of confident statements about the prospects of the company's then-forthcoming Lumia range of Windows Phone handsets. On April 11th, however, Nokia issued a warning that its quarterly performance would be worse than expected. The company posted losses of €1.34 billion ($2.17 billion) for the first quarter of 2012. Combine that with the $100 rebate for early Lumia 900 buyers—a move that knocked 16 percent off Nokia's share price—and the company's shares have taken a beating.
As is customary, Nokia's forward-looking statements were all suitably disclaimed. The Private Securities Litigation Reform Act of 1995 has a "safe harbor" provision that protects companies from legal action should their forward-looking statements turn out to be untrue. Nokia included the necessary wording to indicate that the statements were dependent on market conditions and many other factors, and that reality might diverge from its predictions.
However, Chmielinski argues that Nokia isn't protected, because Elop and other company officers knew that the forward-looking statements were false, and were not related to any business plan or projections. Chmielinski is claiming class-action status, with anyone who invested in Nokia in that six-month period included in the class.
Nokia has issued a statement saying that it is aware of the lawsuit, believes it to be without merit, and is investigating further.


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|Biosequences .. Software .. Molbio soft .. Network News .. FTP
Life Science Journal for All the Scientists: A Formal Journal - Life Science Journal has been published in The United States from this year (ISSN 097-8135). The Life Science Journal is an international journal dedicated to the dissemination of fundamental knowledge in all areas of life science. It publishes full-length papers, reviews and rapid communications on the life science field. Research Reports and regular manuscripts that contain new and significant information of general interest are welcome. The journal is collecting article now. Besides of the submission of the original copy of the printed manuscript we would also appreciate it if you could submit a IBM formatted computer diskette. The publish fee: US$20/page. For further information, please contact: Editorial Supervisor of Life Science Journal, 1527 Hatch Road, Okemos, Michigan 48864, USA, Telephone: (517) 349-5824/(517)355-7782, E-mail: chengu at pilot.msu.edu or hongbao at pilot.msu.edu Thank you for your contribution! -- ********************************************************** Ma Hongbao, Ph. D. 702 Cherry Lane Apartments, Apt. 107 Michigan State University, East Lansing, MI 48823, USA Telephone: [517] 355-7782 [Home], [517] 432-0623 [Office] E-mail: hongbao at pilot.msu.edu Home Page: http://pilot.msu.edu/user/hongbao **********************************************************


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Complete Story
Charter Emerges From Chapter 11 Bankruptcy Protection
By: Mike Farrell, Multichannel News
Charter Communications said Monday that it has completed its restructuring and has emerged from bankruptcy protection, ending an eight-month process.
Charter filed for bankruptcy protection on March 27, reaching agreement with the majority of its bondholders on a plan that would shave $8 billion in debt from the company's books and pump about $3 billion of new equity into the company.
In a statement, Charter said that it has successfully emerged from bankruptcy and that it would issue a new stock no earlier than 45 days after emergence. That would put the earliest date for a new stock offering sometime after Jan. 14.
"This successful financial restructuring is a significant accomplishment and makes Charter a stronger company for the benefit of our customers, vendors, employees and the communities we serve," said Charter CEO Neil Smit in a prepared statement. "We have restructured our balance sheet without losing sight of serving our customers and maintaining our business relationships. Charter will remain focused on further enhancing the customer experience and is positioned to generate free cash flow. On behalf of the management team, I would like to thank the more than 16,000 Charter employees across the country for their hard work and dedication throughout this process."
Charter has said that it is positioned to generate positive free cash flow through the reduction of more than $830 million in annual interest expense. Charter's outstanding debt now stands at about $13.5 billion, or around 5.4 times projected 2009 cash flow, in line with its publicly traded MSO peers.
While details on the new stock are few, Charter offered a peek into its plans last week in a filing with the Securities and Exchange Commission, where it appeared to set a maximum proposed price for the shares of $19.37 each.
In an SEC filing Nov. 25 for a new employee stock ownership plan, Charter said that it is authorized to issue as many as 1.17 billion shares in total, including 900 million shares of Class A common stock, 25 million shares of Class B super-voting stock and 250 million shares of preferred stock. In the filing, Charter proposed setting aside about 3.8 million shares of Class A common stock with a maximum offering price of $19.37 per share for employees.
That would be around the price that Charter stock originally traded when it went public in November 1999. Charter's initial public offering was priced at $19 per share, opened at $21.50 per share and the stock climbed as high as $26.31 each in its first week of trading. The stock had fallen on hard times since - it's peak in the last five years was $5.69 per share - and it had traded under $1 each in the months leading to Charter's bankruptcy filing on March 27.
Charter received approval for its reorganization plan - which would reduce its debt by $8 billion and pump $3 billion of new equity into the company - on Nov. 17. Also last week, a group of lenders and bondholders who had tried to block approval of the plan were rejected in their request for a stay of that approval while they filed an appeal. U.S. District Court Judge Sidney Stein rejected the motion for a stay, stating that the lenders hadn't shown the necessary possibility of success on appeal, according to a Bloomberg News report.
Source: http://www.multichannel.com/article/391033-Charter_Emerges_From_Chapter_11_Bankruptcy_Protection.php


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Chris Kaman on Potential Trades: 'I don't care'
With the NBA trade deadline looming in 11 days, the Hornets remain open to trading veteran center Chris Kaman, according to league sources. But Kaman said he doesn't care what the Hornets may decide to do before the trade deadline."I dont care what they do,'' Kaman said. "So if they want to trade me, trade me. If they want to keep me, keep me. I don't care, but not in a disrespectful way. I just know I can't control that part of it, so it something I don't care about.
HoopsVibe's Very Quick Call: Chris Kaman isn't at fault for this. Commissioner David Stern and the 30 owners he represents are.
Remember, Kaman came to the Hornets from the Clippers in the Chris Paul trade. The Hornets, who are owned by the NBA, had to accept an inferior package from the Clippers after Stern vetoed a blockbuster swap involving the Lakers and Rockets.
Stern nixed Paul joining the Lakers because he was concerned about the optics of a glamour team getting a superstar days after ushering in a supposedly more equitable Collective Bargaining Agreement.
Instead of getting a package of Luis Scola, Kevin Martin, Lamar Odom, Goran Dragic, and a first round draft pick, the Hornets accepted Kaman, Eric Gordon, and other pieces.
All for optics.
Gordon has been injured. And Kaman, who struggled behind Emeka Okafor, was told earlier in the year by management to go home and wait for a trade. He recently returned when a trade couldn't be found.
The bright side to this saga: Kaman's $14 million per year contract expires at the end of the regular season.
So, the Hornets will get cap space if a deal can't be found.
Got thoughts? Well, get at HoopsVibe News in the comment box below.


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Turner Cube, 1990s
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Zone 3 Public Safety Council aims to be a unified voice for residents concerns
May 26, 2009
If all goes as planned, the Zone 3 Public Safety Council will soon become the main and united voice of the 11 neighborhoods in the Zone 3 police district.
Zone 3 Commander Catherine McNeilly plans to prioritize officers' attendance at community meeting to specific problems rather than monthly appearances. She said the officers' time is better spent working on projects that better deliver service to the residents.
Commander McNeilly would like "focused" monthly meetings with the Zone 3 Council on the most important and significant issues in the neighborhoods so that they may be addressed and tracked efficiently and effectively. She said there would still be time that the police would attend local community meetings, when appropriate.
Zone 3 Public Safety Meetings will now be held in the fourth floor Conference Room of the station at the corner of Arlington and Warrington avenues. They will be continue to be held on the third Wednesday of each month, except in January and August, and will begin at 6 p.m.
Due the size of the conference room the revamped council will be limited to two representatives from each of the 11 neighborhoods of Zone 3. The meetings will still be open to the general public, but those attending are asked to contact Officer Luffey so accommodations can be made for their attendance.
Commander McNeilly stressed that the station is still accessible by calling the same number, 412-488-8326, and that Crime Prevention Officer Christine Luffey can still be reached by calling 412-488-8425, or by email at email@example.com .pa.us.
Mr. Wolfe said the Zone 3 council is currently working on a Website for the Zone where anyone may log on to find out meeting information, download Silent Complaint Forms and more.
The next meeting of the Zone 3 Public Safety Council will take place on Wednesday June 17, 6 p.m., at the station.


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Saturday, October 24, 2020
Palestine mourns a dear friend, Jo Cox, British Labour MP murdered last Thursday in West Yorkshire
- June 19, 2016
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Jo Cox, 41 year old Labour MP for Batley and Spen in West Yorkshire was murdered in her constituency on Thursday. She was shot and stabbed multiple times in broad daylight on the steps of her constituency surgery. Shortly after the attack, the suspect, 52 year old Thomas Mair was arrested and weapons were recovered, police said at a press conference. According to The guardian, at least two witness said that the killer screamed "Britain first" as he stabbed and shot Cox. Before standing for parliament, Cox had been the Oxfam aid agency's Policy Chief in Brussels. She was elected in May 2015, for the Batley and Spen constituency in West Yorkshire, Northern England, and was going on a promising political career. Jo Cox was deeply involved in the Palestinian cause and was an active member of the Labour Friends of Palestine and the Middle East group. Last February, she challenged the Conservative Government on the proposed ban of the Boycott Divestment and Sanctions movement in the UK, and defended the right to boycott companies involved in Israeli settlements: "I believe that this is a gross attack on democratic freedoms. It is our right to boycott unethical companies". She also launched a survey on the Israel boycott ban. She was well known for her advocacy work on the rights of Palestinian children, in particular denouncing the way in which children are arrested, detained and treated by Israeli forces in the occupied Palestinian territories. Dr. Mustafa Barghouti, founder of PMRS knew Jo Cox from the ranks of the Parliamentary Solidarity with Palestinian People : "We lost in Jo Cox a very important leader of the Labour Party in Britain, a wonderful person who was committed to the people, committed to supporting social justice and who was a very close friend to the Palestinian people and a great supporter of our Palestinian cause. We sympathize with her family, we express our solidarity and deepest condolences to her family, and we think her assassination is an example of how far racist behavior can go and how far people who believe in racism can go in terms of killing honest people."
Her assassination is an example of how far racist behavior can go and how far people who believe in racism can go in terms of killing honest people
The PLO Executive Committee Member Dr. Hanan Ashrawi add that Palestine Mourns "the death of 'Palestine's dear friend and peace and justice activist." She added that "MP Cox, a devoted humanitarian and member of the Labour Friends of Palestine and the Middle East, was a passionate, courageous leader and human rights defender who tirelessly advocated for various causes, including the plight of Syrian refugees, Palestinian child prisoners and an end to the illegal blockade on Gaza." Jo Cox was also a prominent advocate for refugees globally. She supported the recent campaign for giving shelter to refugees in the UK, especially for refugees fleeing the war in Syria. During a debate in April 2016 Cox called for greater support for child migrants and refugees, saying "I know I personally would risk life and limb to get my two precious babies out of that hell-hole." The MP's husband, family and friends have set up a fundraising page in memory of Jo Cox on Friday to raise money for the charities that she was personally committed to. In less than a day the page has reached more than £500,000 - proof of the affection that many hold for Cox.
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When Phil Ciganer stood on the stage of the Towne Crier in Pawling on New Year's Eve 2011 and announced that he would be closing the historic venue once his lease expired, suggestions and offers as to where he could relocate came in immediately. As in: that very same night.
When Phil Ciganer stood on the stage of the Towne Crier in Pawling on New Year's Eve 2011 and announced that he would be closing the historic venue once his lease expired, suggestions and offers as to where he could relocate came in immediately. As in: that very same night.
"One of the members of the horn section who was playing that night and ringing in the new year came up to me and said, 'Hey, I'm a contractor. I do most of my work in Beacon, and there's this great space on Main Street you should take a look at," Ciganer recalled.
Ciganer had been to Beacon many times in the 1970s and '80s when he was working on the Clearwater Music Festival. He'd often give Beacon native Pete Seeger a ride down to the festival. "I always made sure my car doors were locked when I was going through town," he said with a chuckle. "Beacon was a very different place back then. But I didn't know that my recollection was totally different from what was actually happening here today. So I told him, 'Beacon's not for me.'"
Ciganer searched the Hudson Valley and beyond for the Towne Crier's next home, but nothing felt right. Friends, colleagues and strangers kept urging him to give Beacon another chance.
Finally, he returned to Beacon and took a look at the old DMV building on Main Street, which had stood empty for more than 15 years.
"l looked at the space, I took a walk up and down Main Street and the light went off. I thought, 'This is it.'"
Tonight, the lights go on for the Towne Crier's grand reopening. The rootsy psychedelic band The Grand Slamboivans — who was the last band to play the previous incarnation of the Towne Crier back in June — will play to a sold-out house. It will mark not only the next chapter in the Towne Crier's 40-year history, but in Beacon's history as well.
Beacon has come a long way from Ciganer's memories in the 1970s and '80s. When the Dia:Beacon opened here in 2002, it kickstarted this former industrial town's transformation into a thriving arts community. With the opening of the Towne Crier, it's now poised to also become the live music capital of the Hudson Valley.
Local musician Stephen Clair, who played a warmup gig at the Towne Crier last weekend to promote his new album, "Love Makes Us Weird," remembers when this wasn't the case.
Clair moved to Beacon in 2007 and was disappointed that the city had no real live music scene to speak of.
"I wanted to be in a place that great live original music," Clair said. "And that's not where I landed."
He began inviting bands that he knew to come to town and play anywhere he could find a spot: coffeehouses, art galleries, restaurants with outdoor decks, anywhere. When he put on a night of live music at the Howland Cultural Center and packed the place, he realized that the momentum was building. "Without having ever been a presenter of music, I found a community of people who were hungry for it and appreciated it and trusted me."
Tom Schmitz had a similar realization when he opened the bar and live music venue Dogwood at the far west end of Main Street last year. Like Clair, Schmitz was a Brooklyn expat who came to Beacon in search of something different.
"Brooklyn feels played out," Schmitz said. "But this feels like Brooklyn felt in 1982: really wide open, lots of opportunity and a nice small community where everyone knows each other. Now is the time for Beacon." The first night Dogwood opened, Schmitz had the same experience as Clair at the Howland Cultural Center. "We got hit by a wall of people."
Schmitz is doubling down on the Beacon revival with the imminent reopening of Quinn's Luncheonette. He took over the beloved Main Street diner a few months ago when the original owner retired. Although he's keeping the decor intact — including the faded brown Canada goose wallpaper and the misspelled sign out front — the menu will be a little different. "We're hoping to open soon as a Japanese restaurant during the day, bar food at night, and when we're ready we're going to look to add live music shows in the future."
Thanks to Quinn's and the Towne Crier's reopenings, the much maligned middle section of Beacon's Main Street is undergoing a revival of its own. Ciganer points out that while the historic East and West ends of Main Street have flourished, the middle section of Main Street still has remnants of the old Beacon that he used to avoid. "But everyone's cleaning up their act," he said. "Us being here helps give a facelift to this section of town, and things are really starting to move forward."
Realtor Charlotte Guernsey of Gate House Realty, who was instrumental in getting the old DMV space on Main Street developed, said there are more people looking to open businesses on Main Street than there are available spaces. She thinks the Towne Crier will finally bring foot traffic to the middle of Beacon's main street. "It's going to be a great anchor for Main Street and a real destination."
For his part, Ciganer is so impressed with Beacon that he's been rethinking some previous decisions. "This is a blossoming community, something we can really contribute to and be in good company right here on Main Street," he said. "Maybe this is what I should have done in 1972."
The past can't be changed, but Beacon's future is looking brighter than ever. For Stephen Clair, it's been a long time coming.
"Finally, this is the place I dreamed of moving to."


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It Could Happen to You1994 - 101 minutes Movie A waitress gets a life-changing tip when a cop comes up short on pocket change and promises her half of his potential winnings from a lottery ticket.
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Recruited by a secret society of babysitters, a high schooler battles the Boogeyman and his monsters when they nab the boy she's watching on Halloween.


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Disconnect therapy for depression, phobias, anxiety, headaches, allergies, sleep problems, dyslexia, stage fright, depression etc.
The following menu includes discussions of the various causes of mental problems and what
you can do about them. In all cases, the voice therapy I present attempts to disconnect you
emotionally from past emotionally upsetting events in your life, remembered or not, that may
be causing at least a part of your problem.
I now have about 50 videos of disconnect therapy on YOUTUBE . I have no idea how they compare in effectiveness with this website.
If you are taking a mood-altering drug, it is unlikely anything on these pages or my videos will help you. In some way the drugs interfere with reprogramming the subconscious. That is my experience. Maybe others have different experiences. I do not do smoking and weight-loss because for me the success rate is very low. You have to want to change and most people don't, so it's a waste of time.
There are lots of words on my pages, but written words won't get you well. Neither will talk. What you must have done to have a chance of functioning better is get a reprogramming of your subconscious mind. That is best done by voice "disconnect therapy" on my pages. There are two sources. The streaming audio you see with player buttons at the bottom of the pages, and the automated therapy which is a telephone call in to a computer and is listed just below. And now the YOUTUBE site. Each has its merits. Repetition of the message often helps. All is free. All is experimental and not everyone will be helped. Nothing goes "snap". You just generally feel better and cope with stresses better.
Most popular pages for this website are fingernail biting, headaches, anxiety and sex techniques.
Additions: I have added information on physical diseases as I am now active in the alternative health movement for cancer and heart disease. See "Physical Diseases" below.
About Psychological Research Foundation, Inc.
Disconnect therapy is used in all the following exercises. Please note: I am not a doctor.
Sound file to disconnect you from stage fright
Possible help for asthma
Possible help for chronic anxiety
The Subconscious Mind
Depression as a result of an abortion
Fingernail biting
Ordinary Headaches
Migraine headaches
Disconnects you from humiliating and embarrassing experiences
Voice messages meant to improve your self esteem
Panic attacks
Fear of thunderstorms
Food Allergy
Skin diseases
Simple Therapy
How this simple therapy works
Notes for Therapists
Automated Therapy by Telephone (It really works! With 36 different messages you can select)
Sound file to disconnect childhood upsets to age 12
Sound file to disconnect high school upsets
Sexual problems: Adults only, please. This is explicit information on techniques and problems frequently encountered in sexually dysfunctional adults or those who would like to function better.
Therapy for men's sex problems
More therapy for men's sex problems
Therapy for women's sexual response problems
Therapy for women who can't climax with man inside.
A page for men to help their women
Lovemaking techniques for men using suggestion
Therapy for the "Wet Noodle" syndrome
Physical Diseases (primarily Cancer):
I have a website now entirely devoted to cancer and the mind.
All articles below were published in Medical World (defunct) up to 1935 by doctors who were getting people well of terrible diseases at virtually no cost, using very dilute hydrochloric acid and potassium salts. I found it extremely interesting, and if you have an interest in cancer and some other "incurable conditions", you may enjoy (relish) reading it too. Copy was scanned and may have errors. Loren Parks 3-5-2002
Introduction to Three Years of HCl Therapy
Hydrochloric acid therapy (cancer in general --1935)
Acid Mineral Chlorides (cancer in general --1935)
Toxemia and Alkalosis (1935)
The Conquest of Cancer (1935 article)
Relation of Iron to Cancer (1935)
The Treatment of Cancer (1935 article)
Nature is the Best Doctor (infections, tuberculosis)
Hydrochloric Acid Produces Leucocytosis (acute infections, nephritis))
The Metchnikoff Idea
A Further Report of Cases (1935 article)
Hydrochloric acid therapy (Hodgkins Disease -- 1935)
HCl therapy in the jungles of Mexico (malaria, meningitis, tetanus, smallpox, scorpion bites, pain control, pneumonia, diabetes -- 1935)
These audio files are in Real Audio format. You can download the free Real Player here if you don't have it. Real Player streams the audio, and will start playing almost immediately, depending on your connection speed. If you're on dial-up, it may take a minute or two to load.
Streaming audio on the web to disconnect you emotionally from your ex-husband
Streaming audio on the web to disconnect you emotionally from your abusive childhood.
Streaming audio on the web to disconnect you emotionally from the death of a loving husband
Streaming audio on the web to disconnect you emotionally from a person
Streaming audio on the web to disconnect your craving for sweets
Audio on the web to possibly help you lose weight.
Streaming audio on the web to disconnect you emotionally from the causes of a learning disability
Streaming audio to disconnect you emotionally from a loving mother's death
Streaming audio to disconnect you emotionally from death of a pet
Streaming audio to treat the emotional upset from being jilted
Streaming audio to treat fear of flying
Streaming audio on the web to disconnect you emotionally from putdowns (derogatory remarks by others)
Streaming audio on the web to disconnect you emotionally from the possible cause of some of your headaches
Streaming audio on the web to disconnect you emotionally from early experiences causing motion sickness
Streaming audio on the web to disconnect you emotionally from the emotional upset following an abortion
Streaming audio on the web to disconnect women emotionally from early guilt about sex
Audio file to disconnect you from upset over a death.
Streaming audio to disconnect cause of hair pulling
Streaming audio to disconnect cause of a driving phobia
Streaming audio to disconnect you from several mother issues
Mesmer came up with "Animal Magnetism" in the 1700's and later James Braid, M.D. in the 1800's in England with "Hypnosis". A pioneer in the U.S. was Milton Erickson, M.D. In about 1921 he came up with what we now call "ideomotor finger signaling", a method of getting the subconscious to talk back to the therapist in response to questions that have YES, NO, or I DON'T KNOW answers. Hypnosis was not recognized by the American Medical Association as a valid healing method until 1966. No matter how you look at it, SUGGESTION is the necessary element. Getting the subconscious to ACCEPT the suggestion is the problem. I do what the stage hypnotists do. I use a suggestion and a "trigger" to install the suggestion (click on the mike or sound a buzzer), but I don't use hypnosis.
Many years of using various therapeutic techniques have shown me who can be easily helped and who cannot. People in ongoing, acute stress are less likely to be helped than those with chronic emotional problems (assuming normal intelligence). But if the condition is long standing, the emotional component of the causes can be disconnected by a simple technique I'm glad to share. What I do is Pavlovian in nature (from Psych. 101 in college). I try to extinguish conditioned responses installed in the subconscious by upsetting emotional events of the past.
I have an extensive background in group hypnoanalysis as well as with individuals, and most of the phenomena of the deep trance in hypnosis. I never use the deep trance in therapy (as Dr. Erickson did) because it doesn't work better than the simple methods outlined in these pages. I have not "hypnotized" anyone for at least 15 years because it isn't necessary to get the results I'm after. In fact, it's a hindrance since so many people are not readily hypnotizeable and are afraid of it because of movies they've seen. Also they have a preconceived idea as to what it is to be in hypnosis and it is totally false. In the deep trance, one does not realize it until afterwards, when he realizes some time has passed.
If I work with someone in person and have the time, I will use hypnoanalysis and ideomotor finger signaling as described by the late David Cheek, M.D., in his recent book "Hypnosis--The Application of Ideomotor Techniques." I cannot teach you that method on the web, nor perform it by automated therapy. But the simplified technique I describe works well for many people. Keep in mind that in hypnoanalysis or working with someone on the phone, I clean out a whole bunch of garbage from the past, not just one thing. I tailor-make the therapy to that person. That's why the telephone automated hotline or the streaming audio can only do so much. But if you choose the right message fitting your past, it can work quite well.
Also, we are using suggestion. Suggestions can "wear off" after a while. Maybe hours, days or months, even years. It wears off rapidly if you get under stress. By all means, repeat the exercise as much as you want or need.
Failures to cure or lessen depression are caused primarily because the person is still living in the stress situation and/or is on a tranquilizer. I don't know why it is, but this therapy and I suspect all others are not as effective when the person is on a tranquilizer or is hyperactive.
There may be nutritional or hormonal causes for depression after menopause. DHEA at the health food store may help people over 40. Loneliness, poverty, illness, out of work, love affair or marriage gone bad, etc. are difficult to deal with because they are ongoing.
Things I do work best for events or relationships that are over and done with. You'll do best having a friend work with you for ongoing stress. I am not skilled at teaching self hypnosis nor have I had much luck with it.
I am what is known as a "Lay Therapist." All I do or present is free. I do the best I can to give people insight into how our minds work, using the internet and my quite extensive personal experience.
NOTE: The author of this page is not a state or medically-licensed professional.
Loren Parks,
Psychological Research Foundation, Inc.
P.O.Box 5669
Aloha, OR, 97006
Please send questions to: firstname.lastname@example.com


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I Did It My Way: Best Customized Kids' Projects — Best of 2012
Editorial Rating:
Average Rating: ( 0 votes)
One of the biggest decorating trends, which shows no sign of slowing down, is customizing your home and the pieces in it. You're not starting from scratch with a pile of wood, but you're taking an existing object and putting your own stamp on it: sometimes literally. Here are ten of our favorite custom jobs from the past year: • IKEA Malm Gets an Upholstered Ombre Makeover • A Graphic Remedy for the Malm Dresser • 10 DIY Glider & Rocker Makeovers • Modern Craft Idea: Cross Stitched Cane Back Chair • By the Numbers: Numerical Dresser & Wardrobe Makeovers • A Customized Fire Station Play Structure • 10 Ways to Customize the Kura Loft Bed • DIY Kids' Plate • Make It Yours: DIY Kids Table Makeovers • IKEA Expedit as LEGO Playhouse More


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Recipe from Eva Sherwin of Denham Springs, La.
handful of dried chili de arbol
3 cloves of garlic
1/4 onion
1-8 oz. can tomato sauce
1/8 c. oil
2 c. of corn masa
2 c. beef broth
1 tsp baking soda
2/3 cups lard or shortening
pinch of oregano & cumin
pack of dried corn husks
First boil meat until it's tender.
Remove from heat.
Boil chili until soft.
De-stem and put in blender with 4 cups cold water 3 cloves of garlic and 1/4 of onion, tbls. salt, and 8 oz. can tomato sauce.
Blend and strain seeds out.
In large skillet, add 1/8 cup of oil over med high heat, add chili, pinch of oregano, and cumin and stir until boiling.
Shred and add meat and stir until mix begins to boil again, add just enough cold water and corn starch to thicken.
Remove from heat.
While cooling slightly, separate and rinse your dry corn husks then place them in warm water to soften.
In large mixing bowl, add 2 cups corn masa, 2 cups broth or water, (I use 1 cup broth and 1 cup chili) baking soda, 1/2 tsp salt, and2/3 cup lard.
Mix should be kind of spongy and soft, adjust water oil or masa as needed.
You are now ready to assemble tamales. Spread masa mix over corn husk, spoon meat/chili mix over masa flip sides and bottom of corn husks towards center. Place in steamer. Stack tamales in standing up. Cover with towel then place lid on pot. Steam for 1- 1 1/2 hours. (Tip: put a penny in pot, if penny starts jumping around lower heat.)
*DISCLAIMER*: The information contained in or provided through this site section is intended for general consumer understanding and education only and is not intended to be and is not a substitute for professional advice. Use of this site section and any information contained on or provided through this site section is at your own risk and any information contained on or provided through this site section is provided on an "as is" basis without any representations or warranties.


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I have created a new website where I will be posting helpful information on the college admission process as a homeschool student. I have learned a lot of helpful tips from my personal experience as a homeschool college applicant and would love to share it with you all!
I will be posting updates regularly and would love to answer any questions you might have! I have done extensive research on college admissions and have worked closely with admission officers from different colleges to learn more about how they review homeschool students.
My site is: http://homeschoolapplicant.wordpress.com
Homeschooling + College Admission
How do you organize what your children have done into a record of work? Discuss this and other related issues here!
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Thank you for your information on college admission.
I saw your website where you try to provide information to us on college admissions. It is really not only informative but also helpful to us. Although there are other sites like collegehelp1.com helps students to get admissions in a better college but your site helps students to choose best college where they should learn.
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LOS ANGELES, Calif. - J.J. Redick gave Orlando its first lead on a 3-pointer with 42 seconds left, Arron Afflalo tied his season high with 30 points, and the Magic beat the Los Angeles Clippers 104-101 on Saturday to snap a 10-game skid.
The loss ended the Clippers' franchise-record 13-game, home-winning streak and provided them with a scare when All-Star guard Chris Paul went down holding his right knee with 54 seconds to go. Paul returned after a timeout and hit a 15-footer to draw his team within one with 33 seconds left.
But the Clippers turned the ball over on Jamal Crawford's offensive foul. Josh McRoberts found Nikola Vucevic open under the basket, and Vucevic dunked to extend Orlando's lead to 104-101 with 8 seconds left.
After a timeout, Crawford missed a 3-pointer as time expired.
Redick added 21 points, and Vucevic had 18 points and 15 rebounds for the injury-riddled Magic, who ended the franchise's longest skid since 2003-04 while also stopping a four-game road losing streak.
Blake Griffin tied his season-high with 30 points, Crawford added 13 points, and Paul had 10 points and 16 assists for the Clippers.
Crawford's 3-pointer gave the Clippers a 95-87 lead in the fourth. But the Magic rallied to tie the game at 95-all with eight straight points. The run was capped by Vucevic's jumper after Afflalo made a 3-pointer while being fouled by Matt Barnes, who picked up his fifth.
The Magic had earlier fourth-quarter leads against Miami, the Knicks, Portland and Denver, but were unable to finish. Not this time against a sluggish Clippers team that was coming off two days' rest, as was the Magic.
Orlando opened the third with a 17-9 run, including 12 by Afflalo to make it 66-66.
Powered by Griffin, the Clippers ended the period on an identical 17-9 spurt to lead 83-75. Griffin scored their final 10 points, highlighted by an alley-oop dunk and back-to-back hook shots, the latter banking in on a turnaround move.
Grant Hill made his season debut for the Clippers, entering the game to a standing ovation in the fourth. The seven-time All-Star had missed 36 games with a bone bruise in his right knee. He made two free throws and had two rebounds in six minutes.
The Magic had been struggling since big man Glen Davis hurt his left shoulder on Dec. 19. They finally won their first game without him, improving to 6-11 on the road and 13-23 overall since he got injured.
The Clippers led by 13 points twice in the first half. The Magic tied the game three times in the second quarter before the Clippers restored their lead to double digits on a 3-pointer by Paul that capped a 13-0 run.
NOTES: Hill played his 998th NBA game. He hadn't played since Oct. 13 when he had eight points and three rebounds in an exhibition game against Miami in Shanghai. ... Magic coach Jacque Vaughn said Davis is progressing back in Orlando and there's "nothing negative" in his rehab. ... Clippers coach Vinny Del Negro watched his alma mater, 20th-ranked North Carolina State, upset No. 1 Duke before his game. ... Vaughn spent the team's off-day visiting his parents in nearby Pasadena, where he starred as a prep player. ... Shaquille O'Neal sat courtside wearing a Dodgers hoodie, while Dodgers manager Don Mattingly attended, too.


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Ashampoo Internet Accelerator 3 3.20
Ashampoo Internet Accelerator analyzes your computer and optimizes all the relevant settings with a single click
We all take the Internet for granted nowadays but what your computer has to do to allow you to surf is actually amazingly complicated. Windows has a long list of settings for tuning the performance of your Internet connection. Thats fine if youre a computer expert, the rest of us will generally make things worse rather than better if we can find all the well-hidden settings in the first place. Ashampoo Internet Accelerator analyzes your computer and optimizes all the relevant settings with a single click. You dont need to know anything, just select the automatic optimizer and youre done. The new version also includes an Internet connection speed test tool so you can test your performance directly. In addition to automatic optimization advanced users can still access all the individual settings and adjust them manually. Easier to use, plus new tools and settings: Weve redesigned the layout, making the program even easier to use. Everything is explained directly, youll probably never have to refer to the help. In addition to this weve also added a set of new tools and features for managing your Internet connection.


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Skip to 0 minutes and 13 seconds Here we are at Limestone Corner. And this is a great place to think about how the Romans built the ditch in front of the wall. For the most part, they could have used tools like these, a spade, a reconstructed spade, and mattock. But unfortunately, the geology was not terribly understanding or forgiving. This is not an area of limestone at all. What we're dealing with here is volcanic rock. And this is one of those cases, where Roman military efficiency came up against the natural order and lost. And we can actually see that moment. Soldiers have clearly come through. They've cut away a ditch here, despite the hard rock. And then they've got to this point. They've prepared the stone for breaking.
Skip to 0 minutes and 57 seconds We can even see where they've tried to drive or started to prepare to drive wedges into the stone to break it, and they've given up. It's an interesting moment in the history of the wall.
Facing the enemy: why bother with a ditch?
To the north of the Wall lay a ditch, normally omitted only where the presence of crags and marshes rendered it unnecessary.
Its appearance varied from place to place, but it was generally between 8.23-8.53 m (27-28 ft) wide. Some of the material from the ditch was smoothed out to make a mound to the north, other elements may well have been used to help build the Wall itself. How important was the ditch to the Hadrian's Wall system? It clearly had a role to play, but it is fascinating to see what happened when the Roman working party began digging a ditch at Limestone Corner. Unfortunately, despite its modern, rather ironic name, the geology of this area is not characterised by nice soft limestone, but by brutally hard volcanic dolerite! One wonders who decided what to do next. An interesting point to note is that while the Romans did not complete the ditch to the north of the Wall here, they did persist in completing the vallum to the south, despite the fact that it obliged them to cut through the same stone!
© Newcastle University


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Reddish/Pink Sapphire
ZigZag™ Cut
ZigZag™ Cut
Browse through our selection of custom cut Leaf/Flame gemstones below. Click the photo of a colored gemstone you are interested in to view more information about that stone.
Looking for more gems like these? Check out our other pages using the navigation below.
If you are a retailer, please register here or call 1-715-830-0126 for wholesale pricing.


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Copyright 2012 © Deere & Company. THIS DATA IS THE PROPERTY OF DEERE & COMPANY. ALL USE AND/OR REPRODUCTION NOT SPECIFICALLY AUTHORIZED BY DEERE & COMPANY IS PROHIBITED.
All information, illustrations and specifications in this manual are based on the latest information available at the time of publication. The right is reserved to make changes at any time without notice.Foreword


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Concert in the Park is another of my favorite traditions. This year we had absolutely amazing weather. One week we were even a little bit chilly!
I took the kids to Coconut Cove for the first time. It was so awesome. We practically had the place to ourselves. Shannon and I sat and chatted while the kids played. It was perfect!
We did some fun 4th of July crafts at home. The kids painted Popsicle sticks and we turned them into flags. So cute!
Ava came and grabbed me one day in the family room and ran over to the kitchen. She was so proud to show me what she had done. Emptied all the ikea dishes out onto the floor and arranged them like this. So cute!
Cute sisters. Kallie set this all up for them.
Another craft at Michael's. We went with neighbors this time and had a blast.
Kallie asked me to match Ava's outfit and hair to her own, so of course I obliged.
Then Kinley and I discovered we were matching too, but on accident.
Lunch at Arctic Circle.
We went swimming at Scera with Brandon one evening after work for a couple hours before the pool closed and it was so much fun. Not crowded at all and we enjoyed every minute.
My sweet friend Kawehi invited us over one afternoon to enjoy her shaded backyard and we had so much fun visiting while the kids sang kareoke and ate snacks.
More park days!
Another friend Rebecca had us over for a fun water day in her backyard and fed us lunch. We had such a great time!
Jessica and Ryan invited us for a family swim party to celebrate Mady's birthday. Ava wasn't feeling well so I spent a lot of time sitting with her on the side but it was still a great day.
This pool had the most amazing view and the kids had a blast jumping off the diving board over and over.


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Everything should be waterproof. Especially phones, because you know how you love to poop and talk. You can thankfully drop Fujitsu's new line of waterproof Android phones and tablets in the crapper without ruining them.
The 10.1-inch, 16GB tablet has a 1GHz Dual Core processor, 1280 x 800 WXGA display and front and rear facing cameras and has an LTE antenna so you can Internet like a crazy person. Even crazier, it has a remote hand gesture function so you can control the tablet without actually touching it. Also, we used it while submerged in a fishbowl. The future! The one I saw was running Honeycomb, but Fujitsu said it would be upgradable.
Meanwhile, the slim little Android phone is equally waterproof, has a Gorilla Glass front with a 4-inch 480 x 800 AMOLED display, and is a mere 6.7 mm thick. It only has a rear facing camera, and well, Android 2.3. But come on, you can make calls with it from underwater. Again, the future!
No pricing was available on either.


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Howell / University of Illinois at Champaign-UrbanaAdditional media resources available at right. To book an interview, click on the "Book an Interview" button.
Thursday, July 29, 2010
News releases: 7/29/2010 | 7/12/2010
Fired U of I professor vindicated, will again be allowed to teach Catholicism classU of I says Kenneth Howell will continue as adjunct professor
Thursday, July 29, 2010
ADF attorneys representing Howell sent a letter to university officials on July 12 explaining that the university's actions violated his rights protected by the First Amendment and asked that he be reinstated.
"A university cannot censor professors' speech--including classroom speech related to the topic of the class--merely because certain ideas 'offend' an anonymous student. We greatly appreciate the university's move to put Professor Howell back in the classroom, but we will be watching carefully to make sure that his academic freedom is protected throughout the university's ongoing process," said ADF Senior Counsel David French.
A letter from the University of Illinois Office of University Counsel admits no wrongdoing on the part of the university but states, "The School of Literatures, Cultures and Linguistics will be contacting Dr. Howell to offer him the opportunity to teach Religion 127, Introduction to Catholicism, on a visiting instructional appointment at the University of Illinois, for the fall 2010 semester. Dr. Howell will be appointed and paid by the University for this adjunct teaching assignment."
The letter then adds that a university committee will continue its investigation of Howell's situation.
Howell, who had been teaching at the university since 2001, was relieved of his teaching duties based in part on an anonymous complaint sent via e-mail to university officials. The e-mail was sent by the friend of an anonymous student who claimed to be "offended" by a May 4 e-mail Howell sent to students elaborating on a class discussion concerning Catholic beliefs about sexual behavior.
The May 4 e-mail from Howell addressed a May 3 lecture in which he explained how the Roman Catholic Church distinguishes between same-sex attraction and homosexual conduct. He accurately stated the church's teaching that homosexual conduct is morally wrong, framing the issue in the context of natural moral law.