text:
YES! As an additional reward, you can expect to obtain No cost benefit shipping and delivery on a considerable selection of non-suitable Transport
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Dotpay, What is it?
Dotpay is a third-party online payment platform established in Poland. For any company with a Polish target audience and international growth ambitions, Dotpay is a highly recommended payment method.
Dotpay, How does it work?
Dotpay is a payment method for Polish customers. A customer can choose his own bank in order to pay with Dotpay.
If the transaction is approved by Dotpay, the transaction status will change to completed and MultiSafepay will add the funds to the balance of your MultiSafepay Control.
Dotpay transaction flow
|Order Status
|Financial Status
|A payment link has been generated, but no payment has been received yet.
|A successful Alipay transaction has been received and the funds will be added to your MultiSafepay Control balance.
|Transaction has been rejected.
|An unfinished transaction will automatically expire after a predefined period.
|Transaction has been canceled.
Dotpay transaction, refund status flow
|Order Status
|Financial Status
|A refund has been requested.
|Refund has been successfully processed.
Full API reference on the payment method Dotpay.
Product rules
Some rules may apply to certain payment methods. These rules apply to the payment method Dotpay.
The lifetime of a payment link can be adjusted. This might be beneficial for your inventory. The adjustment can be processed through the days or seconds active.
Full documentation on the lifetime of a payment link can be found on our FAQ page, Lifetime of a payment link
The payment method Dotpay processes the currencies
Euros (EUR)
Zloty (PLN).
Providing first and last name of the customer is mandatory to finalize a payment with the payment method Dotpay. This can not be entered on the payment page. The transaction will automatically be rejected.
How to activate Dotpay
Note: Before applying for the payment method Dotpay, check with your account manager at MultiSafepay if you are eligible for the payment method.
Dotpay is an additional payment method. Therefore, an application is required. Submit your request by contacting your account manager or contact us at [email protected]
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MultiSafepay does not allow you to refund more than the stated amount of the original transaction
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The customer will receive the refund to the bank account number in which the transaction was originally paid to, within the next business day.
Outgoing payments will not be processed if your MultiSafepay balance is insufficient.
When you are not able to refund a Dotpay transaction, contact our support department at [email protected] to assist you further.


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The two major approaches to studying macroevolution in deep time are the fossil record and reconstructed relationships among extant taxa from molecular data. Results based on one approach sometimes conflict with those based on the other, with inconsistencies often attributed to inherent flaws of one (or the other) data source. Any contradiction between the molecular and fossil records represents a failure of our ability to understand the imperfections of our data, as both are limited reflections of the same evolutionary history. We therefore need to develop conceptual and mathematical models that jointly explain our observations in both records. Fortunately, the different limitations of each record provide an opportunity to test or calibrate the other, and new methodological developments leverage both records simultaneously. However, we must reckon with the distinct relationships between sampling and time in the fossil record and molecular phylogenies. These differences impact our recognition of baselines and the analytical incorporation of age estimate uncertainty.
Abundance is one of the primary factors believed to influence extinction yet little is known about its relationship to extinction rates over geologic time. Using data from the Paleobiology Database we show that abundance was an important factor in the extinction dynamics of marine bivalve genera over the post-Paleozoic. Contrary to expectations, our analyses reveal a nonlinear relationship between abundance and extinction rates, with rare and abundant genera exhibiting rates elevated over those of genera of moderate abundance. This U-shaped pattern is a persistent feature of the post-Paleozoic history of marine bivalves and provides one possible explanation for why we find strong support for heterogeneous extinction rates among genera grouped by similarity in abundance yet effectively no net relationship among these rates when using models of directional selection on abundance.
All evolution attributable to natural selection, at any level, is due to a causal covariance between fitness and phenotype. Over macroevolutionary time scales, species selection is one of many possible mechanisms for generating large-scale morphological trends. For species selection to sort morphology, a correlation between morphology and taxonomic diversification rate must be present. Other trend mechanisms (driven mechanisms, e.g., a bias in the direction of speciation) produce a systematic change in the mean phenotype over time. All mechanisms can co-occur. Here I demonstrate (1) an inverse correlation between diversification rate and calyx complexity that demonstrates the effect of species selection on morphology. Genera with simple calyces tend to increase in diversity, whereas genera with complex calyces have a net decrease in diversity; and (2) the presence of a driven trend mechanism in monobathrid crinoids where descendant genera tend to be simpler than their ancestors. The separate effects of these two classes of trend mechanisms can be combined by using the Price's Theorem, which partitions the contribution to the overall change in calyx complexity over time accurately among selection and driven mechanisms. Price's Theorem provides significant conceptual and methodological clarification of the contribution of multiple and interacting hierarchical mechanisms in generating large-scale trends.
Atmospheric dust constitutes particles <100 μm, or deposits thereof (continental or marine); dust includes 'loess,' defined as continental aeolian silt (4–62.5 μm). Dust is well-known from Earth's near-time (mostly Quaternary) record, and recognized as a high-fidelity archive of climate, but remains under-recognized for deep time. Attributes such as thickness, grain size, magnetism, pedogenesis, and provenance of dust form valuable indicators of paleoclimate to constrain models of atmospheric dustiness. Additionally, dust acts as an agent of climate change via both direct and indirect effects on radiative forcing, and on productivity, and thus the biosphere and carbon cycling. Dust from the late Paleozoic of western equatorial Pangea reflects ultimate derivation from orogens (ancestral Rocky Mountains, Central Pangean Mountains), whereas dust from southwestern Pangea (Bolivia) reflects both proximal volcanism and crustal material. Records of dust conducive to cyclostratigraphic analysis, such as data on dust inputs from carbonate sections, or magnetism in paleo-loess, reveal dust cyclicity at Milankovitch timescales, but resolution is compromised if records are too brief, or irregular in interval or magnitude of the attribute being measured. Climate modeling enables identification of the primary regions of dust sourcing in deep time, and impacts of dust on radiative balance and biogeochemistry. Deep-time modeling remains preliminary, but is achievable, and indicates principal dust sources in the Pangean subtropics, with sources increasing during colder climates. Carbon cycle modeling suggests that glacial-phase dust increases stimulated extreme productivity, potentially increasing algal activity and perturbing ecosystem compositions of the late Paleozoic.
EPA has conducted several ex post assessments of regulatory compliance costs, with the ultimate goal of identifying ways to improve ex ante cost estimation. The work to date has culminated in four case studies that examine five regulations using a common conceptual framework. The standardized framework provides a systematic way to investigate key drivers of compliance costs to see if judgments can be made about why and how ex ante and ex post estimates of costs differ. In addition to describing this conceptual framework, we describe the criteria used to select the rules to be analyzed, summarize the main hypotheses for why ex ante and ex post cost estimates may differ and discuss some of the challenges encountered in conducting these ex post analyses.
Everything biological varies. Without variation, evolution would not be possible. This is a truism in macroevolution as much as it is within and between organisms. Species vary in their phenotypic and macroecological traits (Brown 1995) and variation also exists in the taxonomic rates of speciation and extinction over time (Alroy 2008), among taxa (Van Valen 1973; Sepkoski 1981; Raup and Boyajian 1988), and within taxa (Van Valen 1973, 1975; Liow et al. 2008; McPeek 2008; Simpson and Harnik 2009; Simpson 2010). Variation in diversification rates produces the major patterns of diversification we observe in the fossil record. Understanding the patterns and causes of variation in diversification rates has been the focus of palaeobiology for decades (Simpson 1944, 1953; Van Valen 1973; Raup 1978; Gould and Calloway 1980; Sepkoski 1981; Raup 1991a, 1991b).
Palaeobiologists, however, are not the only ones interested in understanding the patterns and causes of diversification. Diversification is also interesting to ecologists for at least two reasons. Major spatial patterns of diversity such as the latitudinal diversity gradient are likely to be underpinned by historical patterns of speciation and extinction (Jablonski and Hunt 2006; Krug et al. 2007, 2008; Kiessling et al. 2010). Also, many distributions of ecologically important traits, for example body size, may be, in part, a product of the historical patterns of differential diversification (Stanley 1975; Van Valen 1975). The second interest is the issue of diversity limitation. Data from the fossil record and molecular phylogenetics of extant organisms have been brought in to study this issue and evidence is accumulating that diversity is, in fact, constrained (Cracraft 1982; Nee et al. 1992b; Paradis 1997; Pybus and Harvey 2000; Nee 2001; Ricklefs 2007; Alroy 2008, 2009, 2010; Alroy et al. 2008; McPeek 2008; Phillimore and Price 2008; Rabosky and Lovette 2008a, 2009b; Phillimore and Price 2009; Quental and Marshall 2009, 2010; Rabosky 2009b).
Carbon aerogels with tailored pore sizes were prepared by using a combination of sol-gel processing, supercritical CO2 extraction and pyrolysis. Ruthenium particles were incorporated via impregnation of organometallic precursors using supercritical CO2, followed by in situ thermal reduction. TEM studies reveal that the carbon aerogels are characterized by a continuous pore structure and that the ruthenium particles are highly dispersed with a narrow size distribution. It is found that under certain circumstances the carbon aerogels undergo a structural transition under the electron beam, in which the original tortuous aerogel network transforms into onion-like structures.
We initiate the reverse mathematics of general topology. We show that a certain metrization theorem is equivalent to Π1
2 comprehension. An MF space is defined to be a topological space of the form MF(P) with the topology generated by {N
∣ p ϵ P}. Here P is a poset, MF(P) is the set of maximal filters on P, and N
= {F ϵ MF(P) ∣ p ϵ F }. If the poset P is countable, the space MF(P) is said to be countably based. The class of countably based MF spaces can be defined and discussed within the subsystem ACA0 of second order arithmetic. One can prove within ACA0 that every complete separable metric space is homeomorphic to a countably based MF space which is regular. We show that the converse statement, "every countably based MF space which is regular is homeomorphic to a complete separable metric space," is equivalent to . The equivalence is proved in the weaker system . This is the first example of a theorem of core mathematics which is provable in second order arithmetic and implies Π1
2 comprehension.
Let n be a positive integer. By a βn-model we mean an ω-model which is elementary with respect to formulas. We prove the following βn-model version of Gödel's Second Incompleteness Theorem. For any recursively axiomatized theory S in the language of second order arithmetic, if there exists a βn-model of S, then there exists a βn-model of S + "there is no countable βn-model of S". We also prove a βn-model version of Löb's Theorem. As a corollary, we obtain a βn-model which is not a βn+1-model.
The longevity of the Berlin and Kay theses results from the
way in which they were formulated, contrasted with extreme relativism.
Saunders & van Brakel need not reject colour opponency to reject
universal colour categories. Colour opponency does not manifest itself
in language, even when dealing directly with spectral
Email your librarian or administrator to recommend adding this to your organisation's collection.


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What Android Smart Watch Works Best With Sprint
What Android Smart Watch Works Best With Sprint
Where the Galaxy Watch fails is in its third-party app assistance and also dependence on Samsung software application and services. There just aren't many third-party apps offered for it, and also the third-party watchfaces, though abundant, aren't extremely great. If you make use of the Galaxy View with a phone that's not made by Samsung, you'll likewise need to mount countless apps on your phone to make it possible for all of its attributes, which is annoying.But apart from What Android Smart Watch Works Best With Sprint .
those issues, the Galaxy Watch has to do with like it obtains for Android users.For years Samsung's Equipment series of smartwatches have been dominating the market for all the right reasons. When you take smart marketing and incredible products in order to combine them together, this is what takes place. The Gear S3 is absolutely one of my much-loved smartwatches.Right out of package, you can inform that the S3 is a top smartwatch;
launched earlier this year, the S3 concentrates on everything that was right in the previous versions, and also includes even more features than before. Sure, I know it sets you back relatively higher than some of the other options on the list, but it is okay.Starting off, the construct quality is exceptionally pleasing, with exceptional high quality products used throughout the building. The watch definitely feels like a fashion declaration as a lot as it seems like a premium smartwatch.Unlike some of the various other smartwatches on the market, the Gear S3 does not work on Android Put on, rather, it runs on Samsung's very own OS called Tizen. Prior to my testimonial, I had my uncertainties regarding this OS as it is still something brand-new, and also unknown to me.Luckily, upon utilizing the watch for a week, I can claim that the OS is appealing, however, the serious lack of apps may keep some individuals at bay. Samsung recently pushed What Android Smart Watch Works Best With Sprint
an updated to this watch, permitting you to save offline Spotify playlists onto the 4GB of storage.This function makes my life very easy since I no longer have to rely on my information connection to pay attention to the music whenever I am outdoors. The Gear S3 has an animated always-on display, and also unlike a few of the various other watches I make use of on a typical basis, this is one lovely screen, politeness of Samsung.Another great point that I such as about the Gear S3 is the reality that it comes loaded with task trackers of all kinds, and also while a number of individuals could really feel doubtful about it, particularly when you think concerning the quantity of authorizations it requires. It really is not that big of a problem to be honest.The Gear S3 additionally provides an excellent, intuitive user interface that is among the very best I have seen in any smartwatch.
All of these excellent features integrate and also make this a leading smartwatch. I do have some worries that are needed to be checklist out.For starters, the watch looks huge on your wrist; currently that is something that completely depends on just how your wrists are. This is a subjective problem of course, yet I still think it is essential to direct it out. An additional thing that was a frustration was the sheer absence of proper apps. What Android Smart Watch Works Best With Sprint
That is mainly because of the fact that Tizen is still a smartwatch OS that is creating, and also progressing. If you are fine with these small aggravations, after that I can inform you that the Samsung Equipment S3 is definitely one of the very best smartwatches 2017. Designer smartwatches are catching on, yet most of alternatives available most likely come from Fossil Group's rankings-- and also
among the finest amongst them is the exceptional Skagen Falster 2. It's a unisex watch that is available in a unisex size, although it's undoubtedly one of the a lot more manly coatings in the Fossil Team line-up. Slim and also light, the Skagen challenges those that complain that smartwatches are too beefy, packing a complete 1.19-inch OLED touchscreen. In terms of size, the case has been diminished to 40mm, which as small as any type of smartwatch available-- and also it's extremely light as well. At 0.8 mm thick it's no Daniel Wellington, yet it's as comfortable as any full-screen Put on OS beware there.
It takes a basic 20mm band, so you can virtually pick anything from the analogue watch world to pimp out your smartwatch.There are downsides for a tech perspective. It made use of older Qualcomm modern technology so battery life is mired around a single day's use and we did see some efficiency problems. If you're looking for design initially as well as technology second-- and also there is absolutely nothing incorrect with that-- the Skagen Falster 2 is well worth your time.Fossil Group might be holding the umbrella over a lot of style residences generating smartwatches, but that does not mean it's not completing in the field itself. As well as with its fourth-generation smartwatches, it's generated maybe the most eye-catching smartwatch on the market, from a style perspective.Sharing some resemblances with the older Michael Kors Gain access to Sofie (our previous ideal style watch pick ), the Fossil Q Endeavor Human Resources desires to stand out, and also followers of an extra elegant watch will possibly locate it a far better fit than those who such as to maintain their wrist wear understated.Fossil is still maintaining display resolution and various other specs under wraps, however we do understand this generation(which includes the men's Fossil Q Explorist Human Resources)is the most feature-packed we have actually seen from the firm.
Building on the design renovations of the third-gen devices, which saw the flat tire eliminated and also a slimmer form aspect, the Q Endeavor HR now likewise harbours some serious tech under the bezel.There's now a heart price monitor, as the name suggests, for tracking beats throughout the day and also throughout exercise, a GPS keep track of to stay on par with your exercises, as well as an NFC chip to allow Google Pay. Add to that the ability to take this underwater up
to 50 metres, all on the top of the renewed Put on OS, and all of it complete as a very total smartwatch experience.One of our leading smartwatch picks for women alongside the Fossil Q Venture is Michael Kors'Gain Access To Runway. The iPhone and also Android-friendly operate on Google's Wear OS and also builds on the previous generation Michael Kors smartwatches, going big on looks once again.Its 41mm case houses a lovely 1.19-inch 390 x 390 AMOLED touchscreen display screen.
There's your option of stainless steel as well as leather bands, and it's additionally offered in a somewhat much more expensive Ceramic model.On the features front, the Runway brings integrated GPS, a heart rate monitor, a swimproof design and also Google Pay to allow contactless repayments.
It's possibly not ideal fit to go with a run with, but if you care regarding using Google's fitness tracking functions, it more than does the job.Google's Wear OS certainly runs the software program program so you're also obtaining notice assistance, Google Assistant, the capacity to transfer music to your watch as well as customisable watch encounters.
There's personalized Michael Kors enjoy faces there as well to much better praise that fashionable watch body.Battery life is the Wear OS smartwatch standard, so you can expect to obtain you through a day as well as possibly a little additional. Profits, you'll need to bill it every day.If you're not planning to obtain perspiring with it and you're searching for a
seriously good-looking smartwatch, the Runway most definitely fits the bill.Luxury smartwatches are a thing and some of them are really extremely excellent. It began with Tag Heuer's smartwatches after that the similarity Louis Vuitton joined the connected celebration as well. Currently Montblanc desires in.Features such as heart price displays, and variety of
other sensing units have actually made their way right into the smartwatches, permitting them to truly change the wearable experience into something much better, and functional at the very same time.Since the marketplace at this factor is full of smartwatches of all sorts, we took it on ourselves to have a look at the finest smartwatches you can purchase, but initially, we are mosting likely to be looking at several of the essential information regarding the smartwatches.Its first smartwatch was underwhelming however, in its second coming, the Top 2 is a watch that provides on layout and on features.
Montblanc has designed its second generation watch on its 1858 collection offering smooth original watch encounters, a high quality construction and also an excellent 1.2-inch, 390 x 390 resolution touchscreen display.Google's Use OS runs the program, however Montblanc handles to leave its mark with extra apps as well as those watch faces we discussed to assist points feel even more unique.
It's now loaded with more hardware attributes including built-in GPS, a heart rate monitor as well as a totally waterproof style to add any type of extra layer of durability.This is also one of the first Use OS smartwatches to work on Qualcomm's new smartwatch tech that offers performance improvements throughout
the board consisting of battery life. You're not going to obtain a week out of it, however it must make it with the day and also maybe a little extra.The brand-new fitness functions may not be best, but it behaves for the laid-back gym goer
. When you're not sweating it out, it'll rest there looking beautiful.The bulk of smartwatches in our checklist have actually been full-screen gadgets, yet
the Withings Steel Human Resources approaches points a little in different ways-- yet is still a powerful connected watch in a plan that evaluates simply 49g. The analogue display shows the time on the main dial (with a month of battery life )and also progress towards your action objective on the 2nd dial-- yet there's a lot more taking place than this.The Withings Steel HR has a 24/7 heart price display that will certainly maintain tabs on VO2 Max as well as it will certainly match up with a mobile phone to track exterior workouts using GPS, although the technology isn't built into the watch itself. It's likewise swimproof to 50m as well as isn't as well shoddy in
the pool either, tracking sizes as well as laps What's more, Withings Wellness Companion application is just one of the most effective around for maintaining tabs on all your diverse wellness data.The remainder of the smartwatch field is largely included variants of Use OS devices that run Google's real smartwatch platform.
The problem with many of these devices is they really feel a minimum of a generation(or more)behind where Apple and also Samsung go to with wearables. They have less features, worse battery life, as well as commonly thick, clumsy designs. Based on our experience, the Use OS enjoys that get on the best are ones made by Fossil and also its secure of brands (such as Skagen), which are readily available in a selection of styles and sizes.It's adept as a connected watch either, as well as will certainly notify you to notices on your smart device making use of vibrations as well as the small OLED screen build into the bezel.
This is qualified of supplying quick and relatively unrefined signals, yet
can reveal you when a message/call/calendar signals are coming through using fast icons.It's a stripped back smartwatch experience however one that's loaded right into an elegant, small as well as comfortable hybrid that does not make as many compromises as you 'd think.Huawei is still selecting its Watch 2, yet in 2018 returned to the table
with something completely various. The Huawei Watch GT packs a huge collection of functions however on top of a personalized os-- those are words we usually utter with a substantial amount of trepidation, yet the Watch GT supplies two weeks of battery life, which is a compelling sell.And it does not scrimp on technology. Huawei has actually loaded in a 1.39-inch, 454 x 454 AMOLED display. Which is amongst the best we have actually played with, conveniently comparing with the vibrancy as well as intensity located on the Galaxy Watch and Apple Watch Series 4. Lite OS might remove several of the much deeper components formerly located in Huawei smartwatches, it's still an excellent task tracker with heart rate monitoring and also sleep tracking.Sports tracking on the basic
is great, but there is one gripe we do have: data can not be shared with third-party applications. Every one of your information can only live inside of Huawei's buddy Health and wellness application. We also located the heart price data to delay means behind achieved sporting activities tracking rivals.Huawei makes huge assurances in the battery division: approximately two weeks with regular usage, a full day of GPS monitoring as well as as much as a month with attributes like always-on display and GPS shut off. And it provides. Despite constant heart rate monitoring transformed on, we've just had to charge the Watch GT when during our three weeks of use.There's now brand-new Huawei Watch GT Classy and active versions that uses a much less flashy appearance yet comes with every one of the exact same attributes including a brand-new Triathlon tracking mode. For those seeking Pebble-esque durability, but want to give up the glitz and attraction of a completely formed operating system and also all the apps and also glamour-- the Huawei Watch GT is an interesting option. As well as with its fourth-generation smartwatches, it's generated possibly the most appealing smartwatch on the market, from a style perspective.Sharing some similarities with the older Michael Kors Accessibility Sofie (our previous finest fashion watch pick ), the Fossil Q Endeavor HR wants to stand out, and followers of a more dressy watch will probably locate it a far better fit than those that such as to keep their wrist wear understated.Fossil is still maintaining display resolution and also other specifications under wraps, but we do know this generation(which includes the guys's Fossil Q Explorist Human Resources)is the most feature-packed we have actually seen from the company. There's customized Michael Kors enjoy faces there also to better compliment that stylish watch body.Battery life is the Use OS smartwatch norm, so you can expect to get you through a day and also maybe a little extra. Currently Montblanc desires in.Features such as heart price screens, and also huge selection of
various other sensing units have made their method into the smartwatches, enabling them to genuinely transform the wearable experience right into something better, and also functional at the same time.Since the market at this factor is filled with smartwatches of all sorts, we took it on ourselves to take an appearance at the finest smartwatches you can get, yet initially, we are going to be looking at some of the essential details regarding the smartwatches.Its first smartwatch was underwhelming however, in its 2nd coming, the Top 2 is a watch that delivers on design and also on features.Montblanc has designed its second generation watch on its 1858 collection offering streamlined original watch deals with, a high grade building and also a top notch 1.2-inch, 390 x 390 resolution touchscreen display.Google's Wear OS runs the program, yet Montblanc manages to leave its mark with extra apps as well as those watch encounters we pointed out to help things really feel even more special. Which is among the ideal we've played with, conveniently matching up with the vibrancy as well as sharpness discovered on the Galaxy Watch and also Apple Watch Collection 4. Also with continuous heart rate monitoring transformed on, we have actually only had to bill the Watch GT as soon as during our 3 weeks of use.There's currently new Huawei Watch GT Sophisticated as well as active editions that supplies a less stylish appearance but comes with all of the exact same attributes including a new Triathlon tracking setting.
Having a small computer strapped around your wrist is no much longer a wishful thinking. The Apple Watch and also other alternatives from preferred makers, like Fitbit, Samsung, LG, as well as Fossil, have actually been gunning to craft the best smartwatch. Now a couple of years extra fully grown, the smartwatch market supplies even more than ever before, whether you're after a particular style, iOS and Android phone compatibility, or simply a bunch of features.Smartwatches remain in disrespectful
health however when it pertains to the most effective smartwatch in 2019, it's undoubtedly the Apple Watch Collection 4. However it comes at a cost, and there are a lot of top smartwatches at cheaper costs and with equally great health and fitness features.Whether you're seeking a fantastic smartwatch for physical fitness monitoring, running or a just taking notifications and phone calls-- there are a lot of fantastic alternatives for every single budget plan. What's even more, smartwatches are getting a lot more stylish too.Today's best smartwatch bargains f you have actually got an Android phone, the Apple Watch will not operate at all, and also
the most effective choice here is Samsung
's Galaxy Watch. The Galaxy Watch does collaborate with both apples iphone and also Android gadgets, however it's finest with an Android phone, as well as specifically, one made by Samsung.The Galaxy Watch has most every one of the functions you 'd expect on a modern-day smartwatch: GENERAL PRACTITIONERS, touchscreen, multi-day battery life, voice control, mobile payments, as well as heart rate monitoring. It has a round face that's simple to review inside and out, and has a really beneficial always-on mode that makes it easy to see the moment at a glance.We're about four years into the Great Modern Smartwatch Experiment, which indicates we've discovered what smartwatches can be excellent for
(physical fitness monitoring, alerts )as well as what they are most definitely not great for(replacing your smartphone entirely). If you remain in the marketplace for a smartwatch, whether that's since you've never possessed one previously and also wonder concerning them or you're aiming to update your older-generation model, you can anticipate today's smartwatches to last a little much longer between costs, be a little faster to achieve points, and perhaps do a pair of new methods you weren't expecting.But the very best smartwatch is still significantly a servant to a smart device, and also also if you fork over for an LTE-connected design as well as pay a solution plan charge for it, it's not going
to free you entirely. Because of that, we do not believe LTE smartwatches are an excellent buy for lots of people-- it's much simpler and less costly to simply maintain your phone with you as well as use your watch as a sort of remote control for the phone in your pocket or bag.Which smartwatch you pick is mosting likely to be based totally on what phone you have, so our picks are broken down right into the most effective alternative for iPhone customers and the very best one for Android owners.The Apple Watch Series 4 is as near to smartwatch perfection as we have actually seen to day-- it's a flexible and powerful wearable that can provide a substantial range of functions. While those trying to find a straightforward smartwatch might locate the Collection 4's massive array of health and fitness, health and linked features to be overkill, it has the ability to change in between fitness tracker, sporting activities watch and also serious health tool at will, making it a significant crowd pleaser.Apple's newest Watch enhancement provides us the most significant layout adjustment considering that the original, bringing brand-new 40mm as well as 44mm dimensions (in contrast to 38mm as well as 42mm). That means more space to display all the most up to date software program attributes presented in watchOS 5. It has just the same core fitness and sports tracking as the Series 3, including built-in GENERAL PRACTITIONERS
for tracking of outdoor workouts and a swimproof design. Fitness monitoring analysis may delay Fitbit, but Apple's special goals-- indicated by the closing of Move, Stand and Calorie rings-- is still a powerful motivator. There's still no indigenous rest monitoring
here, yet this can be done via a third celebration app.The headline functions are the new ECG display that unlocks the capacity for serious heart health and wellness monitoring. It's been FDA got rid of, so the attribute can be utilized to detect heart rhythm abnormalities. It's now offered beyond the United States with Apple including 19 even more nations that can sign in on their heart health from the brand-new Watch. You additionally do not need to do that manually, as well as the Apple Watch constantly monitors for reduced
and raised heart prices, along with AFib. There's additionally a new loss discovery setting that can allow individuals gain access to Siri to get in touch with emergency situation solutions or an emergency situation contact.If you are seeking a fantastic smartwatch that does not set you back a whole lot of money, the S928 Sports Watch may be an excellent alternative. It is one of the cheapest smartwatch on my list, and while I am normally adamant when it pertains to examining such items, it captivated me to the core.The watch is made rather simply, and rather than having a fancy display screen or high resolution, it makes use of a straightforward, monochromatic screen. Honestly, I do incline that at all, smartwatches are everything about being simplified in my point of view, and the S928 Sports Watch does a wonderful job at that.Where it lacks a screen, the S928 Sports Watch composes by offering some of the very best functions that you can want in a smartwatch. In order to make points simpler for the visitor, I am note down the features below.Heart Price Screen: The watch includes a heart rate monitor that has the ability to provide genuine time heart price updates.GPS: The S928 Sports Watch likewise include a constructed in 3D accelerometer +gyroscope3D, allowing the individuals to be able to track every action they make throughout their workout regime.Outdoor Data: The watch is additionally qualified of keeping a record of the outside data, indicating that you get real time updates on how the climate problem is outside. Enabling you to be able to intend your workout carefully.These are several of the standard or advanced functions that are in the watch. While they might not look sufficient, it is necessary to recognize that these functions function throughout the whole ecological community of the
watch, allowing these sensors to take complete control of the situation.The smartwatch can be managed with an application that is readily available on both iphone and also Android. Truthfully, the app is as basic as it can obtain, and also can make use of a bit
much more gloss. There are a couple of more things that I did not recognize regarding the watch; you can not transform the moment format to 12 hours if you desire to.In addition to that, the watch itself just supports English as a language, while the app itself has 12 languages in total amount. This incongruity can be a problem for people who do not have English as their main language, as well as also though 12 languages behave to have, they are simply enough.The advantage here is that the app is being regularly updated by the designer, so I can think that extra
languages will certainly be added at some point in the future. Very same opts for the watch as the firmware can be upgraded when released.All in all, the S928 is a decent smartwatch for Android, it is affordable, functions as it is meant to, and does not come with unnecessary attributes that can drain the battery. I would state that this smartwatch features the bare basics, and certainly has a market amongst the giants.Sure, the lack of advanced features, and languages is startling, yet you additionally require to take price right into factor to consider when you are evaluating a product.Although smartwatches have existed for a long, long period of time, their foray into the mainstream is just recent. With companies like Samsung, Apple, Asus, Huawei, and numerous others are burning the midnight oil to boost the watches, as well as genuinely make the experience a whole lot better.Amidst all this, there exists the customer frame of mind that still thinks that the standard, analog watches are means, means far better as they are crafted with fantastic accuracy, as well as excellence. This has led to numerous discussions how smartwatches shouldn't exist, or are taken into consideration bane of the wrist watch concept.Still, for individuals that in fact like their watches present all the necessary info that comes
to their phone, all tied right into one ecosystem really consider smartwatches to be really helpful, as well as complying with that into the market, the smartwatch industry now is creating a different entity for itself.The Collection 4 comes packing LTE when again so you can take it out sans iPhone as well as still make/receive calls, obtain texts and also all various other notifications you would certainly on your phone. A brand-new audio speaker additionally makes Siri talks and telephone call audio louder as well as clearer.Battery life is
the primary gripe still, as well as for all the renovations, Apple can still only supply 24-48 hrs-- which for many just isn't excellent enough.The Fitbit Versa is the company's 2nd smartwatch and also, in addition to an adjustment in design direction, it's most importantly offered at a more economical price than the Apple Watch-- it can usually be grabbed for around$179.99. And also do not neglect-Fitbit has actually introduced the Versa Lite Edition(more on that listed below)which clocks in at $159. The Fitbit Versa comes in a host of various surfaces and with a large collection of bands to mix up the look. And also thanks to the runaway success of the smartwatch, there's a dynamic market of bands to pick from.The Versa supplies every one of the exact same fitness as well as sports monitoring features you 'd anticipate from the Fitbit ecological community, though the huge omission right here is the absence of GPS. If you wish to track runs and also trips, you'll require to take your mobile phone with you, and also the watch can piggyback your phone's information.
For many this won't be a large issue, however as significant runners it's a degree of difficulty we such as to avoid.Fitbit OS 2.0 brings a new-look UI that supplies much more understandings right into your daily information and also quick reply assistance for Android phone individuals(iOS assistance coming at a later date). You can still download and install apps as well as an entire great deal of watch deals with, pay from your wrist making use of Fitbit Pay, as well as take advantage of Fitbit Coach. The brand-new ladies's health tracking has actually likewise been presented for the initial time, which is likewise offered for the
Ionic, too.But it's battery life that really has the power to oblige buyers, as well as the appealing cost. You can get five days on a single charge, which suggests much less problem on weekends away, and simpler rest tracking.Fitbit had such wonderful success with the first
Versa that it determined to make a less expensive variation that strips out several of the smartwatch features.The Lite is almost identical to the initial Versa in appearances, save for currently just a single physical button on guard body, which implies you'll be relying a lot more on the touchscreen display screen to browse the Versa Lite. In our experience, we really did not miss the second button as well much.In regards to the attribute that are lost, you don't obtain a built-in music player or swim monitoring (it's still waterproof though). You do get an optical heart rate monitor as well as all the conventional physical fitness monitoring as well as sporting activities tracking features in addition to app-based features like ladies's health tracking. There's additionally no much longer Wi-Fi, with Fitbit introducing a new as well as less complicated means to upgrade your smartwatch via step-by-step background downloads.Sports and health and fitness monitoring efficiency is not that various from what we located on the first Versa.
Rest monitoring is still a standout attribute, while the heart price screen still has a tendency to fail for high intensity exercises. As a core smartwatch experience it's suitable, however it still lacks in contrast to its closest competitors.
Specifically in the app department. If you enjoy watch deals with though, you're well offered here.Thankfully you still get the same four-day plus battery life, which can certainly extend to five days depending on use. That's still far better than what Apple and Google's Use OS watches can summon up appropriate now.If you liked the Versa, but like to invest a little much less, the Versa Lite Edition is suitable alternative. The swim tracking is a frustrating noninclusion extra so than the songs player, but if you can live without checking your swimming pool sessions it's still an excellent smartwatch to consider at a terrific price.The Samsung Galaxy Watch is the follower to the Gear S3 and also is still one of the most effective watches around. Compatible with Android and also iOS, it currently can be found in both 42mm and 46mm models.Samsung footsteps in between smartwatch and also health and fitness tracker, also cramming in a heart price sensor alongside the GENERAL PRACTITIONER and also its much-improved Samsung Health software program. There's likewise the option of LTE, if you want an untethered connection, with a standalone audio speaker for taking contact the watch. It's currently waterproof too, including swim tracking abilities that are on par with the Watch Collection 4. The Galaxy Watch runs on Samsung's Tizen OS 4.0 and also really feels like a better alternative to Google's Use OS today. You still obtain that revolving bezel and also among the very best displays you can discover on a smartwatch. The app selection
still delays method behind the Apple Watch as well as Wear OS tools. That stated, the Spotify app is great as well as supplies offline playback.Battery life, we need to state, is additionally strong, obtaining you 2-3 days on the 42mm version and also even more on the 46mm variation.
If you're not a fan of Use OS and don't want an Apple Watch, this is the leading alternative to take into consideration instead.Garmin has actually been producing go-to smartwatches for sports fans for a while currently. Operating, biking, swimming, golf-- Garmin has had us well and truly covered. In spite of the Leader name, the 645 Music is a lot more in the mould of the Vivoactive 3 Music. It's got a similar look as well as likewise brings the music this time. This aids make the Garmin even more of a smartwatch opponent to the Apple Watch, Samsung Gear or Fitbit Ionic than before.Not only are you obtaining sufficient storage for 500 tracks, however you're getting the offline playlist support for Spotify, Deezer and iHeartRadio. For moving your very own tracks, boot Garmin Express on your computer, select the Music tab as well as pick from your very own music to port over.That exact same eye-catching stainless-steel layout is below. The 240 x 240 pixel display screen at the heart of the body is by no indicates the brightest or most dynamic you'll find, but most importantly supplies strong visibility in most exercise conditions, whether you're sweating it out indoors or outside. There is no touchscreen or touchpad below, so you'll have to resort to pressing some buttons.As far as the number of sports available to track: while it's even more of the same, there are some significant exclusions-- like golf tracking as well as open water swimming( pool swimming is there though). Heart rate tracking is decent if not class-leading, and also it will not maintain you lingering for a GENERAL PRACTITIONER signal. There's additionally all the stress and anxiety tracking goodies from Garmin's fitness trackers. As multi-sport smartwatches go, this is the best in our eyes, and also builds on all the great work Garmin finished with its previous iterations.For apple iphone owners, Apple's Collection 4 Watch is by far the ideal choice readily available. The Apple Watch has a huge, bright screen; sleek, comfortable hardware; quick efficiency; very trusted battery life; and an entire host of health and fitness tracking and health-related features. The Apple Watch also has the toughest third-party What Android Smart Watch Works Best With Sprintecological community-- there are many bands, devices, chargers, anchors, applications, and also watchface complications you can use with the Apple Watch.The Apple Watch stands out at offering fast accessibility to any notices that come in to your phone, as well as it allows you respond to messages right from your wrist promptly and easily. You can use it as a speaker phone whenever you seem like replicating Penis Tracy, as well as it's wonderful for regulating What Android Smart Watch Works Best With Sprint
songs playing on your phone. It also has Apple Pay for buying points without a pocketbook or your phone, GPS as well as heart price tracking for workouts, as well as even the ability to advise you if it finds particular heart problems.THE APPLE ENJOY SERIES 4 HAS ALL OF THE FUNCTIONS ANTICIPATED IN A SMARTWATCH Battery life can differ depending on just how much you utilize the Watch to track activities and the number of notices you receive, yet in our testing, the Collection 4 Watch never ever failed to last a minimum of a whole day between costs, as well as often it can choose two days. It's still something you require to bill instead consistently, but you don't have to fret about it passing away on your wrist halfway via the day if you have actually started with a full tank.Unlike virtually every other smartwatch on the marketplace, the Apple Watch still does not supply an always-on display screen, nevertheless, so it does not in fact tell you the moment up until you touch the screen or lift your wrist. It's still extremely ironic that things the Apple Watch is the worst at is being an What Android Smart Watch Works Best With Sprint
actual time-keeping device.But apart from that, there's really little to whine about with the Apple Watch Collection 4, as well as it's easily the best alternative for apple iphone users.Of training course, we're noting the Leader right here as a smartwatch, as well as Garmin has included decent smarts. Health and fitness monitoring is great and Garmin Link is a respectable ecosystem for wellness data from steps and sleep The Galaxy Watch does function with both iPhones as well as Android devices, but it's best with an Android phone, as well as especially, one made by Samsung.The Galaxy Watch has most all of the attributes you 'd expect on a modern-day smartwatch: GENERAL PRACTITIONERS, touchscreen, multi-day battery life, voice control, mobile settlements, and also heart price surveillance. For that reason, we don't think LTE smartwatches are a great buy for a lot of people-- it's far less complicated and also more affordable to just maintain your phone with you as well as utilize your watch as a type of remote control for the phone in your pocket or bag.Which smartwatch you choose is going to be based entirely on what phone you possess, so our choices are broken down right into the finest choice for apple iphone individuals and also the ideal one for Android owners.The Apple Watch Collection 4 is as close to smartwatch perfection as we have actually seen to day-- it's a powerful as well as versatile wearable that can supply a huge variety of features. While those looking for a simple smartwatch might locate the Series 4's substantial selection of physical fitness, health as well as linked functions to be overkill, it's able to morph in between fitness tracker, sports watch and severe wellness tool at will, making it a serious crowd pleaser.Apple's latest Enjoy addition gives us the most significant design change because the original, bringing brand-new 40mm and also 44mm dimensions (in comparison to 38mm as well as 42mm). Honestly, I do not mind that at all, smartwatches are all about being simplistic in my viewpoint, as well as the S928 Sports Watch does a great job at that.Where it lacks a display, the S928 Sports Watch makes up by providing some of the ideal attributes that you can want in a smartwatch. In order to make points much easier for the visitor, I am listing down the functions below.Heart Rate Screen: The watch comes with a heart rate screen that is able to give genuine time heart rate updates.GPS: The S928 Sports Watch likewise come with a developed in 3D accelerometer +gyroscope3D, permitting the individuals to be able to track every step they make throughout their exercise regime.Outdoor Data: The watch is also qualified of keeping a document of the exterior data, suggesting that you obtain real time updates on how the climate problem is outdoors. What Android Smart Watch Works Best With Sprint


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Lisa R.
Love the shirt and coffee mug I got -- great quality, fun saying, attention getting.
Kristen K.
Love the size of the cups and the weight, so many with saying on them are too heavy, these were perfect!
Jeanette D.
Received my mug yesterday, and I love will be showing it off, and will be doing business with you again.
Tawana T.
Love my new shirt and coffee mug...Will use often and will soon order another one!
Pat J.
I received my mug and I love it! In the future I definitely will be ordering more items!
Margo D.
I recently received my cup and was quite pleased with the appearance. Very satisfied with the product.
Cindy H.
I was pleased with my mug, it is heavy and sturdy enough to adequately perform the job of a mug, and the quote suits me to a tee.
Colette B.
I have received my cup and I dearly love it and I give it a 5 star rating and I would send other people to you since I love it so much and thank you so much..
Flo B.
Received the mug free after purchase of sweatshirt. The mug is sturdy and I love the colors on it. The sweatshirt is dark blue and lets the colorful threads stand out. Love it!!
Karen L.
I love this mug. This is now five that I have ordered from your website. The quality of the mugs is amazing and the artwork on them is also truly amazing. I have them lined up in my glass door cupboards so they can be seen when you walk into my kitchen. Each one is exquisite in its own way. You definitely have a customer for life! Thank you for the amazing items you offer!
Bonnie L.
This item was a gift for my mom and she loves it. The processing and shipment were very quick. Would order again.
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|作者:曹云珍 , 张艳萍
|来源:[J].Statistics and Application, 2019, Vol.08 (03), pp.463-470汉斯出版社
|摘要:Objective: Toexplore the influence of non-genetic factors on the incidence of esophagealcancer in Chinese population, and to provide scientific basis for the earlyprevention of esophageal cancer. Methods: Meta-analysis was used toquantitatively analyze 12 non-genetic factors affe...
|作者:张艳萍 , 刘茜
|来源:[J].Operations Research and Fuzziology, 2017, Vol.07 (04), pp.138-147汉斯出版社
|摘要:For semi-infinite programming problems, we provide a new generalized exact penalty function, which contains many commonly used penalty functions as a special case. It is proved that the local optimal solution of the unconstrained optimization subproblem is also the local opt...
|作者:马晓迪 , 张艳萍 , 徐涛
|来源:[J].Pure Mathematics, 2017, Vol.07 (03), pp.155-158汉斯出版社
|摘要:Let G be a finite extension of a finitely generated torsion-free nilpotent group and α be an automorphism of order four of G. If the map G→G defined by Gφ=[g,α] is surjective, then the second derived subgroup G'' is included in the centre of G and CG(α2) is an Abelian g...


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Basso 26 1 Threaded Road Fork 201mm Shaft, 22mm Thread in Purple Made - qdicwq6124-Vintage Bicycle Parts
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*Square Capital, LLC is a wholly owned subsidiary of Square, Inc., d/b/a Square Capital of California, LLC in FL, GA, MT, and NY. All loans are issued by Celtic Bank, a Utah-Chartered Industrial Bank. Member FDIC, located in Salt Lake City, UT. Loan eligibility is not guaranteed. FW0418


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Providence, RI · View map · Visit website
Providence G is a unique wedding venue located in Providence, Rhode Island that will bring your vision to life. The building was originally built in the 1920s, still having those historic architectural details that make it one of a kind.
Facilities and Capacity
Providence G has many versatile event spaces that will provide you with a personalized and elegant experience. Located in the heart of Downtown Providence The Ballroom at Providence G is the cities newest luxury event space. Historically known as the Providence Gas Company lobby, our simple but elegant decor is an ideal setting for weddings, social gatherings, birthday soirées, or any large group event. Our ballroom can comfortably fit 250 guests for seated events, whereas during cocktail style events it can fit in the upwards of 300. Our ballroom is tailored to create a customizable feel allowing clients to generate an event individually unique to their style.
Providence G also has Providence's first and only rooftop restaurant and bar, which can be transformed into the ideal location for an on-site ceremony or cocktail hour.
Services Offered
This luxurious venue has many packages and enhancements that will make your wedding day fun and stress free. Services provided:
Photos from reviews
17 Providence G Reviews
Married on 06/08/2019
Loved this as our wedding venue!
We had our ceremony and reception at the Providence G and absolutely loved it! We had ceremony and cocktail hour on the Rooftop and then reception in the ballroom and both are so beautiful. Our guests ... Read more gave us so many compliments about both spaces. Rebecca and her staff at the G are so wonderful to work with - she is so thorough and patient with questions and helped make our day run so smoothly.
Married on 10/20/2018
Wedding Venue
I could not be more happy with having the Providence G as our wedding venue on October 20, 2018! We had our cocktail hour on the roof deck with the fireplaces and it was absolutely gorgeous and the ... Read more food was great! We had the reception in the ballroom which was so elegant and beautiful! Lastly we had our after party at the G Pub downstairs with snacks and games which was so convenient and fun! The venue itself was great but what made our day beyond perfect was the wedding coordinator Rebecca Miller who did everything from helping us with vendor selections to running around the day of to make sure our day was everything we dreamed of and more - she helped to get a stain out of my dress when I dropped and app and helped with my very difficult bustle and everything in between! I could not recommend the venue and Rebecca more! If you are considering having your wedding here you will not be disappointed!!
Married on 10/14/2018
Rebecca is the MVP
We cannot say enough good things about the experience we had working with Rebecca at the Providence G. From beginning to end, Rebecca was unbelievably responsive, helpful, professional and everything ... Read more in between. As for the venue, it is everything you could ask for. Our guests raved about the cocktail hour on the roof and the ballroom was the perfect space for our ceremony and reception. We rounded out the night in the G Pub with games and late night snacks. Thank you Providence G for making our wedding everything we could have hoped for!
Do you have a site fee for wedding receptions at your venue?
What is the starting site fee for wedding receptions during peak season?
$ 5,500
What is the starting site fee for wedding receptions during off-peak season?
$ 3,500
Do you have a site fee for wedding ceremonies at your venue?
What is the starting site fee for wedding ceremonies during peak season?
$ 500
What is the starting site fee for wedding ceremonies during off-peak season?
$ 500
Which of the following are included in starting site fee?
Bridal Suite, Chairs, Event Planning, Parking, Tables
Which of the following are included in the cost of wedding catering?
What is the starting price per person for bar service?
$ 3
Which of the following are included in the starting price for bar service?
How many event spaces or rooms does your venue offer?
Describe your venue
Ballroom, Garden, Historic Building, Restaurant, Rooftop
What kind of settings are available?
Indoor, Covered Outdoor, Uncovered Outdoor, Scenic Views
Which of the following wedding events does your venue service?
Ceremony, Reception, Bridal Shower, Engagement Party, Elopements, Rehearsal Dinner
What event services do you offer?
Bar Services, Event Planner, Outside Vendors, Wifi
What catering services do you offer?
Cocktail Reception, Hors d'oeuvres
What bar services do you provide?
Bartender(s), Cash Bar, Champagne Toast, House Beer, House Liquor, House Wine, Limited Bar, Liquor License, Open Bar, Outside Alcohol, Premium Liquor, Signature Drink, Specialty Beer, Specialty Wine
What event items are available?
Chairs, Tables
What food and beverage items are available?
What transportation and access is available?
Parking, Valet
What months are included in your peak season?
May, June, July, August, September, October
What months are included in your off-peak season?
January, February, March, April, November, December
1 endorsements
100 Dorrance St Providence, RI, 02903 See on map


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Tools for Call of Cthulhu: Dark Corners of the Earth
Write more, thats all I have to say. Literally, it seems as though you relied on the video to make your point. You definitely know what youre talking about, why throw away your intelligence on just posting videos to your blog when you could be giving us something enlightening to read?


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This FOA will support integrated, interdisciplinary research teams from prior BRAIN technology and/or integrated approaches teams, and/or new projects from the research community that focus on examining circuit functions related to behavior, using advanced and innovative technologies. The goal will be to support programs with a team science approach that can realize meaningful outcomes within 5-plus years. Awards will be made for 5 years, with a possibility of one competing renewal. Applications should address overarching principles of circuit function in the context of specific neural systems underlying sensation, perception, emotion, motivation, cognition, decision-making, motor control, communication, or homeostasis. Applications should incorporate theory-/model-driven experimental design and should offer predictive models as deliverables. Applications should seek to understand circuits of the central nervous system by systematically controlling stimuli and/or behavior while actively recording and/or manipulating relevant dynamic patterns of neural activity and by measuring the resulting behaviors and/or perceptions. Applications are expected to employ approaches guided by specified theoretical constructs, and are encouraged to employ quantitative, mechanistic models where appropriate. Applications will be required to manage their data and analysis methods in a prototype framework that will be developed and used in the proposed U19 project and exchanged with other U19 awardees for further refinement and development. Model systems, including the possibility of multiple species ranging from invertebrates to humans, can be employed and should be appropriately justified. Budgets should be commensurate with multi-component teams of research expertise including neurobiologists, statisticians, physicists, mathematicians, engineers, computer scientists, and data scientists, as appropriate - that seek to cross boundaries of interdisciplinary collaboration.
Invasive surgical procedures provide the unique ability to record and stimulate neurons within precisely localized brain structures in humans. Human studies using invasive technology are often constrained by a limited number of patients and resources available to implement complex experimental protocols and are rarely aggregated in a manner that addresses research questions with appropriate statistical power. Therefore, this RFA seeks applications to assemble diverse, integrated, multi-disciplinary teams that cross boundaries of interdisciplinary collaboration to overcome these fundamental barriers and to investigate high-impact questions in human neuroscience. Projects should maximize opportunities to conduct innovative in vivo neuroscience research made available by direct access to brain recording and stimulating from invasive surgical procedures. Projects should employ approaches guided by specified theoretical constructs and quantitative, mechanistic models where appropriate. Awardees will join a consortium work group, coordinated by the NIH, to identify consensus standards of practice, including neuroethical considerations, to collect and provide data for ancillary studies, and to aggregate and standardize data for dissemination among the wider scientific community.
This funding opportunity announcement (FOA) encourages applications for the Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) D43 program for institutional research training programs in low-and middle-income countries (LMICs, as defined by the World Bank classification system). Applications may be for collaborations between institutions in the U.S and an eligible LMIC or may involve just LMIC institutions if there is a previous track record of externally funded research and/or research training programs by the lead LMIC institution. The proposed institutional research training program is expected to sustainably strengthen the NCD research capacity of the LMIC institutions, and to train in-country experts to develop and conduct research on NCDs across the lifespan, with the long-range goal of developing and implementing evidence-based interventions relevant to their countries. The main focus of research training covered in the application must be relevant to the interests of at least one of the participating NIH ICs as stated by each in this FOA. Other NCD topics may be included as secondary and complementary focus areas.
The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis and manipulation of complex circuits and provide insights into cellular interactions that underlie brain function. Critical advances in the treatment of brain disorders in human populations are hindered by our lack of ability to monitor and manipulate circuitry in safe, minimally-invasive ways. Clinical intervention with novel cell and circuit specific tools will require extensive focused research designed to remove barriers to delivery of gene therapies. In addition to identification and removal of barriers, the need to specifically target dysfunctional circuitry poses additional challenges. Neuroscience has experienced an impressive influx of exciting new research tools in the past decade, especially since the launch of the BRAIN Initiative. However, the majority of these cutting edge tools have been developed for use in model organisms, primarily rodents, fish and flies. These cutting edge tools, such as viral delivery of genetic constructs, are increasingly adaptable to large brains and more importantly are emerging as potential human therapeutic strategies for brain disorders. A pressing need to develop tools for use in large brains, more directly relevant to the human brain is the focus of this initiative. The new tools and technologies should inform and/or exploit cell-type and/or circuit-level specificity. Plans for validating the utility of the tool/technology will be an essential feature of a successful application. The development of new genetic and non-genetic tools for delivering genes, proteins and chemicals to cells of interest or approaches that are expected to target specific cell types and/or circuits in the nervous system with greater precision and sensitivity than currently established methods are encouraged. Methods to track and monito
The purpose of this Funding Opportunity Announcement (FOA) is to support the discovery of promising candidate biomarkers that will facilitate the development of non-opioid therapeutic options for the treatment of pain conditions. The goal of this FOA is to encourage a biomarker discovery process that will result in the development of pain biomarkers that can withstand rigorous clinical and analytical validation. It is hoped that an increased availability of rigorous biomarkers for pain will facilitate the discovery and development of transformational non-opioid therapeutics for pain.
The purpose of this funding opportunity announcement (FOA) is to support the development of novel tools and technologies through the Small Business Innovation Research (SBIR) program to advance the field of neuroscience research. This FOA specifically supports the development of novel neurotechnologies as well as the translation of technologies developed through the BRAIN initiative or through other funding programs, towards commercialization. Funding can support the iterative refinement of these tools and technologies with the end-user community, with an end-goal of scaling manufacture towards reliable, broad, sustainable dissemination and incorporation into regular neuroscience research.
The purpose of this funding opportunity announcement (FOA) is to support the development of novel tools and technologies through the Small Business Technology Transfer (STTR) program to advance the field of neuroscience research. This FOA specifically supports the development of novel neurotechnologies as well as the translation of technologies developed through the BRAIN initiative or through other funding programs, towards commercialization. Funding can support the iterative refinement of these tools and technologies with the end-user community, with an end-goal of scaling manufacture towards reliable, broad, sustainable dissemination and incorporation into regular neuroscience practice.
This Funding Opportunity Announcement (FOA) solicits applications to develop web-accessible data archives to capture, store, and curate data related to BRAIN Initiative activities. The data archives will work with the research community to incorporate tools that allow users to analyze and visualize the data, but the creation of such tools is not part of this FOA. The data archives will use appropriate standards to describe the data, but the creation of such standards is not part of this FOA. A goal of this program is to advance research by creating a community resource data archive with appropriate standards and summary information that is broadly available and accessible to the research community for furthering research.
This Funding Opportunity Announcement (FOA) solicits applications to develop informatics tools for analyzing, visualizing, and integrating data related to the BRAIN Initiative or to enhance our understanding of the brain.
This Funding Opportunity Announcement (FOA) solicits applications to develop standards that describe experimental protocols that are being conducted as part of the BRAIN Initiative.It is expected that applications will solicit community input at all stages of the process. It is recommended that the first step of standard development will involve sharing data between different key groups in the experimental community in order to ensure that the developing standard will cover the way that all of those groups are collecting data. The developed standard is expected to be made widely available.


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