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Sunny Day Beauty
Summer has arrived! Time to brighten and streamline your makeup.
Heavy foundation and loads of liner don't work. Take a cue from your favorite
warm weather clothes and think light, sheer and breathable for summer beauty!
Flawless complexion – without foundation
Apply concealer on imperfections and shadowed areas, blending well. Skip foundation and use a tinted moisturizer (preferably with an SPF).
Your skin will thank you and you won't be worried about foundation running down your face. Tip: choose a waterproof stick concealer for the best hold.
Hold the cream and powder, please
Cream and powder blush and bronzer are more suited for when temperatures drop. Cheek stains and gel bronzers are perfect for the dog days of summer. Use sparingly for a light, sunkissed or pretty flushed look.
Ban the Panda (eyes!)
We all love cute pandas and the marvels of mascara, but no one looks good with panda eyes… those dark rings of flaking, running mascara. Choose waterproof mascara, or the latest tube-technology, which encases your lashes in tiny tubes that act as eyelash extensions… for a fraction of the cost! Not only will your lashes look longer, darker and natural, but tube mascara sets your curl until it is time to remove it. Great for gals whose lashes go limp with humidity.
Go Glossy!
Sheer lip gloss is best for a sizzling summer pout… fuller, riper, even more youthful. Apply a lip stain underneath for more staying power. The newest fresh and fabulous look is deep reds and purples in a sheer gloss!
Get your color pop from nails!
Eyeshadow can be tricky in summer, so indulge your passion for color with bright, polished nails. For a citrus-inspired look, try a neon lime or lemon yellow, for a metallic touch, opt for glittery shades of silver, bronze or marine blues. This summer's fruity shades are cantaloupe or grape. Of course, against a tan, ballet pinks or pearly whites are always classic!
The ultimate summer do… beachy waves!
It's summertime and the living is easy, so your hairstyle should be, too!
Follow our simple steps to create your own waves this summer:
- Start by detangling freshly washed hair with just your fingers.
- Blow dry your roots only, directing your dryer's nozzle down.
- Again, with your fingers, rake a leave-in conditioner through the middle of your hair to your ends.
- Twist your hair into a low bun to create bendy, beachy waves and blow dry the bun.
- When hair is dry, wrap large pieces around a curling iron, leaving the last inch or so uncurled.
- The finishing touch: spray a sea salt spray on palms and gently tug at hair ends.
Tip: This messy-chic style can last for days! Just add a bit of sea salt spray and finger comb your hair to freshen it!
Read more on the subject
Beauty essentials for summer travelRead article +
A practical guide to organizing your makeup kitRead article +
5 makeup trends to try for a radiant summer look!Read article +
Get set for a beautiful Valentine's DayRead article +
Holiday Season make-up trends and tipsRead article +
Summer looks of the starsRead article +
Tips for a natural makeup look at work or at the gymRead article +
Beauty comes in all coloursRead article +
Beauty at every ageRead article +
Get glowing… even in winter!Read article +
How to clean your makeup brushes and other beauty tools?Read article +
Beauty products: Do you get more when you spend more?Read article +
The Balancing Act of MakeupRead article +
Top holiday makeup trendsRead article +
The Midas Touch!Read article +
Back to beauty!Read article +
Be a glow-getter, think pink!Read article +
4 ways beauty products can improve your self-esteemRead article +
Support your Habs with an original 3-colour manicure!Read article +


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Who cares for the Carer article for November Magazine
What is a Carer?
A carer is anyone who cares, unpaid, for a friend or family member who, due to disability, illness, a mental health problem or an addiction, cannot cope without their support.
You would be surprised how many there are and all perform a critical role in the community supporting relatives, neighbours and friends to stay well in their own home. This might be the care a relative offers to a family member with dementia who needs help with their meals or picking up their medication. In another situation a neighbour might be supporting their next door neighbour with a physical disability to manage their weekly shop. A forgotten group of carers are children who may be administering medication to a parent who has a visual disability. Many carers do not recognise the critical role that they are performing and they themselves may need information, guidance or support.
Are You a Carer?
If so Cradley Surgery is here to help you. When completing the Carer's registration form please contact the surgery if you wish to have your details passed on to Herefordshire Carers Support and /or a referral to Adult Care Services for a Carers Needs Assessment.
Our Carers Lead is:
Cradley Surgery
Please Click Here to view Carers Support Policy.
Please Click Here to view Carers Identification and Referral Form.
Herefordshire Carers Support
Is a recognised charity providing practical support and advice to the carer community in the county click here for details http://www.herefordshirecarerssupport.org/
St. Michael's Hospice
Is a local hospice offering various types of support and care for members of the community with life limiting illnesses.
Carers UK
Is a charity set up to help millions of people who look after an older, disabled or seriously ill family member or friend Click here for details http://www.carersuk.or
NHS Choices
There is a wealth of information on the NHS Choices Website (http://www.nhs.uk/conditions/social-care-and-support-guide/Pages/what-is-social-care.aspx
about Carers and Caring.
Here are some links into the site that you may find useful.
Planning for your future care needs (http://www.nhs.uk/Conditions/social-care-and-support-guide/Pages/planning-for-your-future-care-needs.aspx)
What Social Care services are available locally?
( http://www.nhs.uk/Conditions/social-care-and-support-guide/Pages/what-social-care-services-are-available.aspx)
Funding and Care Support ( http://www.nhs.uk/Conditions/social-care-and-support-guide/Pages/funding-care.aspx)
Caring for a Child with complex needs (http://www.nhs.uk/Conditions/social-care-and-support-guide/Pages/parenting-children-with-complex-needs.aspx)

subset: commoncrawl


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May Already Be Suffering From Short-Term Memory LossI've probably written about this, and maybe not that long ago.
I've come to realize that lots of people have "cabins" up here for the summer. I've also come to realize that none of these cabins are ever finished. And they're money pits.
As far as I can tell, cabins are boats on dry land.


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This is not collectible.
Use TB4XJQ2 to reference this item.
First time logging a Trackable? Click here.
Please drop this item in rural OR Premium Member Only caches. Do not place it in an urban cache or abandon it at a caching event. Transport the bug in the original plastic bag for as long as the bag lasts; the bag keeps the trackable clean and prevents tangling with other items. Otherwise, take the travel bug anywhere you wish. No permission is needed to leave the U.S.
Photos in the travel bug logs are appreciated. I will be re-post them here, where they can be seen by other cachers.
Blue 11.5 gram Striped Dice poker chip, white trim.
Gallery Images related to Chip-Blue TB10 blue10View All 2 Gallery Images
Found this puppy with puppies and AnsleyKB/ShineyDime fo the win!
Came from Helen, GA. Enjoy!!
Grabbed this cache in Helen,Ga.
In route to new location
Will find it a good home soon.
Seen in Meister Locked
Move along.
Bear paw-Andy guest Va state park.
Advertising with Us


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In order to unlock items you need to patch your game to 18.104.22.168 version and then go to Hub (for example: Zagore Castle which can be accessed from The Keep>The City Gates, just at the beginning of the game). The items will be dropped on the floor the moment you reach the Hu bfor the first time after patching the game.
Patch 18.104.22.168 will activate all specialGOG-items (once per installation not per in-game character!) without the necessity to redeem the GOG Key. The items will appear ONLY if they weren't redeemed before (in this installation of the game).
Do you have more questions?
Didn't find the answer you were looking for?
We will do our best to respond as quickly as possible. On weekdays, we normally reply within 24 hours, but during weekends we can only respond that quickly to high-priority, time-sensitive cases. All other cases will be looked into first thing next week.Contact us
Want to get help and maybe make some new friends?
We've got a great community here on GOG, which is always eager to help out. Please make sure not to share private data on public forums, though!Ask our community


text:
A few weeks ago I was asked by Irish advertising agency, The Social House, to create some illustrations for their annual Scaryoke halloween bash.
The brief was to create 'scarified' versions of famous pop stars and singers.
The poster was going to be used as an invite to all the guests, and to give them ideas on what to dress up as.
Narrowing it down to just nine singers was a bit tricky, and 'Devilish Presley' didn't make the cut.
We also had to keep one space free for a non-scary singer, but who could look like one at times.
Sorry about that Shane.


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What is a normal glucose level? This question even for doctor's these days is a tough one because so many people don't rely on standard readings anymore they rely on what is normal for that particular patient or diabetic.
A normal glucose level, ranges from patient to patient because what may be normal for me may not be normal for you. Glucose levels also vary from day to day because some people have normal glucose levels for fasting while others have normal glucose levels because of eating everyone has different "normal glucose levels".
A normal glucose level is a good range to have which generally falls in the category of between 70-115/120. If you get higher readings then you could fall into being a hyperglycemic with high blood glucose and if you fall below the 70 range you could be classified as a hypoglycemic with low blood glucose levels.
What is a normal glucose level depends on many different factors such as age, weight, ethnic background, family history and also what type of glucose level you are checking. Naturally if you are checking for a fasting glucose level the readings are going to be lower than if you are checking for a glucose level throughout the day after you have eaten a meal such as lunch or dinner.
What a normal glucose level is, all depends on many things – but by being able to have a normal range to go on it prepares people to know warning signs and symptoms of other problems and conditions if it arises. Why sit back and let something go misdiagnosed or untreated because you aren't sure of the warning signs and symptoms when you can take care of it as it needs to be taken care of. Diabetics not monitoring their blood sugar levels correctly can be dangerous!


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La Hacienda Steel Multi-Function Pizza Oven
- £130.00
Check stock
Tell us where you are to check stock:
About this product
This stylish, multi-function outdoor pizza oven is perfect for those who love dining alfresco. Constructed from durable steel and finished in a stylish black high temperature paint with stainless steel flue, this brilliant pizza oven can cook artisan style pizza, tasty BBQ style treats and can also smoke fish and meats. Includes temperature gauge, cordierite pizza stone, wire bottom shelf, ash tray, air vents and flue damper. Buy today and create homemade restaurant-quality pizza at the fraction of the cost.
- Includes log grate and cooking grill. The perfect centre-piece for you garden! .
- Made from 95% steel.
- Stand and grill included.
- Size H157, W51, D38cm.
- Weight 22.5kg.
- 2 person self-assembly.
The small print
BBQ safety<p>WARNING: Danger of carbon monoxide poisoning - never light this product or let it smoulder or cool down in confined spaces.
*Prices correct as displayed but are subject to change.
The customer and brand answers you'll see above are submitted independently. As we don't review these answers, we can't take responsibility for anything they may say. The responses from Argos colleagues are accurate at the time of publishing. For the latest info, you should check the product page.


text:
Disclaimer: MP3 Song & Video files used in this site are collected from various sources including net, cassettes and CDs. You may downlaod for evaluation purpose only. You should delete them within 24 hours. We are no way responsible for quality or copyright issues. All rights are reserved to the respective owners of the copyrighted material.
|Film Name
|Song Name
|Ovvoru Nanbanum Thevai Machchaan
|Irudhayam mudhan murai veliyilae thudikuthae
|Vignesh Kannan Srisha Vijaysekhar


text:
Machine Á Eau for Cello solo and String Ensemble (1998).
Machine á eau was written under the auspices of the Pépinères europènnes poru jeunes artistes programme with support from PEJA, the City of Mons and the Royal Chamber Orchestra of Mons, Belgium.
First performance: Royal Chamber Orchestra of Mons, with solo cellist Jean-Paul Dessy, at La Machine á eau in Mons, 20th June 1998.


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Monthly Donations
Your monthly support is vital to support our program and the youth and communities that it serves.
TBI's monthly donors find it more convenient to have a small amount of their choosing deducted each month.
You will also be helping TBI have a reliable steady source of funds which allows us to budget and plan more effectively. There's no risk to you either, as we guarantee that you can change or even cancel your monthly donations at any time for any reason simply by contacting us. You can also become a monthly donor through Canada Helps
Your monthly gifts qualify for a tax receipt which will be issued at the end of the year or when your participation concludes.
Cumulative monthly gifts equalling more than $50.00 in one year qualify you to become a TBI member!
2018 monthly donor pledge drive:
Thank you for considering becoming a monthly donor!
Help us reach our goal of 30 Monthly Donors.
Sign up now or between May 1st and 22nd to participate in the pledge drive and win!
Our prizes include:
- Three Nautical books generously donated by the nautical mind
- A 15$ Amazon gift card
- A Framed poster of the T.S. Playfair
Each 5 dollars donated gets you one more ticket entered into the raffle to win.
The names will be drawn on May 23rd so donate today!
Who's donating
Christine Chesterman started a monthly donation 2019-03-30 10:22:28 -0400
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Greg Blake posted about this on Facebook 2018-05-16 13:29:47 -0400Just made a month;y donation to Toronto Brigantine Inc.
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Renee Lehnen posted about this on Facebook 2018-05-01 13:52:19 -0400Just made a donation to Toronto Brigantine Inc.
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Christopher J Donner posted about this on Facebook 2017-04-05 10:01:35 -0400Just committed to a monthly donation to Toronto Brigantine Inc.
Christopher Donner started a monthly donation 2017-04-05 10:00:25 -0400


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A Rotherham supermarket may not fully reopen until Wednesday after thieves ploughed a car through its entrance and drove around the store.
A grey Vauxhall Insignia smashed through the doors of Tesco in Dinnington at around 2am on Sunday before travelling throughout the store.
READ MORE: These are the eight killed in stabbings in Sheffield so far this year
Posting on Twitter, Tesco said: "Due to this closure being caused by a police investigation, I can't confirm exactly when the store is going to open but should be fully functioning by October 10."
READ MORE: Robber jailed for 11 years for targeting elderly women in Sheffield
The Star has contacted South Yorkshire Police for more information and is awaiting a reponse.
READ MORE: Thieves ransack elderly Sheffield man's home while he is in hospital


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Anna Wintour was on Late Night with David Letterman last night. Did you watch? It was fantastic! Loved the banter about his socks. Anna was a very good sport - she didn't back away from Dave's tough questions (i.e. the portrayal of her in the Devil Wears Prada) and showed a sense of humor about her 'ice queen' persona. If you haven't seen it yet you should watch the clip. What do you think about Anna's appearance on Letterman?
Tuesday, August 25, 2009
Labels: Anna Wintour, Vogue
3 comments:
- Jess MyersAugust 25, 2009 at 9:21 PM
Love how she walked out in her shades but then took them off for the interview. Need to see September Issue!ReplyDelete
- AnonymousAugust 25, 2009 at 9:39 PM
Love her and love Dave. Such a fun interview.ReplyDelete
Need to watch that once I get back from work...btw like your blog a lot:)ReplyDelete
Subscribe to: Post Comments (Atom)


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Product Group : Electronics
Product Sub-Group#1 : Audio
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Product Categories : Speakers & Subwoofers
Product Model : VM Audio VAS310P-PAIR-A


text: AOCALA PAREMENT VAC has been set up unknown in state . The current status of the business is . The AOCALA PAREMENT VAC principal address is 000000000 FL368 CYPRESS ROAD, OCAL, A. Meanwhile you can send your letters to FL34472. The company`s registered agent is L 000015601 SW 10 S OC. The company`s management are - Fl34476 000000000000, - 0906200. The company annual reports filed on Annual reports – unknown.


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Mechanic - Fire Safety
Columbia University
Mechanic - Fire Safety
Columbia University
Continue To Application
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February 23, 2019
New York, New York
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Advertised Summary Job Description:
LOCATION: Fire Safety Shop
SCHEDULE: Monday - Friday, 330pm - 12am
The Mechanic is responsible for providing immediate and effective response to work assigned by supervisor, or by job order, and for ensuring that the work is completed in a good workmanship-like manner and that the physical condition of the building is safe and in good repair; ensure that all building certifications and licenses are properly displayed and updated; performs all duties of an Assistant Mechanic and Mechanic Trainee. The Mechanic shall be skilled in the performance of all phases of repair and maintenance and shall demonstrate required knowledge and the safe use of equipment and tools, and shall have the ability to accurately read blueprints, schematics and diagrams. Works independently with complex building systems involving multi-disciplinary skills without supervision. Must provide current and updated home telephone number. In accordance with the collective bargaining agreement, may be required to respond to any emergency on a 24-hour basis and may be required to work overtime. As per Transport Workers Union, Local 241 collective bargaining agreement responsibilities to include - basic knowledge in all areas and skills with a demonstrated proficiency in Preventive Maintenance and at least two of the following skills (Electrical, Plumbing, Carpentry). Responsibilities: As per TWU, Local 241 collective bargaining agreement administrative responsibilities to include: Assist in planning for maintenance repair. Conduct periodic inspections of individual rooms and common areas to report maintenance needs. Maintain accurate and up-to-date records of daily assignments and follow work order process. Effectively perform duties as required by operating and computerized management systems. Recommends products and equipment to be used on assigned jobs, as requested by supervisor. Participate in implementation of preventive maintenance programs and in the development and application of standards of quality and productivity for the facilities. Maintain records to ensure routine compliance with all applicable codes and regulations. Order supplies according to established procedures. Assist in evaluating new equipment for purchase. Calculate quantity of materials needed and requisition all supplies. Perform all related duties, as assigned.
General Minimum Qualifications:
High school diploma, GED or equivalent required. Satisfactory passing of applicable tests. Three years of experience in trades and/or technical discipline.
Additional Specific Minimum Qualifications:
Must have all applicable licenses and permits. Ability to read and interpret documents such as safety rules, regulations, operating and maintenance instructions, blueprints, schematics, diagrams and procedure manuals. Ability to prepare routine reports and correspondence. Ability to interpret and follow instructions in written, oral, diagrammatic or schedule form. Ability to define problems, collects data, establish facts and draw valid conclusions. Ability to interpret technical instructions necessary to carry out the above duties and skills. The incumbent must be able to perform duties on ladders and scaffolding, indoors and outdoors as well as lifting a maximum of 50 lbs. and moving heavier objects with assisted devices. The work environment includes working near or with moving mechanical parts, chemicals and electrical equipment.
Preferred Qualifications:
As a member of the National Collegiate Athletic Association (NCAA) and the Council of Ivy Group Presidents (Ivy League), it is imperative that members of the Columbia University community, in all matters related to the intercollegiate athletics program, exhibit the highest professional standards and ethical behavior with regard to adherence to NCAA, Conference, University, and Department of Intercollegiate Athletics and Physical Education rules and regulations.
Columbia University is an Equal Opportunity/Affirmative Action employer.
Internal Number: 126_174783
Create a Job Alert for Similar Jobs
About Columbia University
Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.
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A brand-new development constructed in the area of what used to be known as the LONG HOUSE, 183 LongHaus will expect for you to present its new offers. The location is ideal at 183 LongHaus for the individuals who just wish to blend in the center of the city, since in the area there are lots of Brand stores and associations to be located. Right through the road, the Thomson Imperial Court are available, alongside the Thomson Community Club, making the building situated perfectly for folks that constantly go to these special areas.
The site is appropriate for redevelopment into a 4-storey mixed-use development with stores on the lower levels and residential flats on the top levels.
The subject property is located next to an exclusive enclave of low rise housing estate in the good sought after Upper Thomson place. It appreciates the advantage of being the approaching Upper Thomson MRT Station, along with near the Marymount MRT Station. The property is conveniently located within proximity to the stretch of shopping, dining and amusement facilities and also Thomson Plaza along Upper Thomson Road.
In regards to folks that simply wish to relax in this region, just around the corner of 183 Long Haus, the Sin Ming Plaza are available, alongside the Shunfu FC Marketplace, for shopping lovers. For those that just want to take a stroll, to begin with, the Nature Reserve are available in only a short space. In case you just intend a straightforward jog, then the Taman Pemata Park is really on the opposite side of the road, only waiting to provide you with a few minutes of quiet and peace. For those who own a family, or if you're thinking about doing thus, in several minutes' distance from the 183 LongHaus, the Soo Chow as well as the Jalan Pinlau Playground Walk Playground are available, a tremendous area wherever your kids may enjoy their time in the wide open atmosphere.
In regards to educational institutions, 183 Long Haus is the place to selected, since the Modern Montessori Preschool are available in the region, together with the Centre for the Whiteley Secondary School as well as Exceptional Children. In the exact same place, a great Medical Center may be discovered, making this an ideal location for folks that are thinking about obtaining work in the Mount Alvernia Medical Centre, or Hospital, or who just need to feel safer by living to a life saving facility. By saying all these, I am hoping the latest building on this particular old area has everything you may want for a completely new location, for your precious family as well as you!
|2 Bedroom
|529/589/556/690/811 sqft
|3 Bedroom
|787 sqft
|4 Bedroom
|1,077 sqft
|433/840/862/1135/1220 sqft
|667/700/1051/1077/1414 sqft
|183 LongHaus
|Property Name
|183 LongHaus
|183 Upper Thomson Road
|District No.
|Total Units
|40 Residential Units + 10 Commercial Units
|Estimated TOP
|Tee Land Limited
|Plot Size
|16, 959 sqft


text:
Hotel Sarthak Palace in New Delhi, is a superb hotel. In New Delhi, Hotel Sarthak Palace offers online booking and comfortable living. Contact Hotel Sarthak Palace in New Delhi for tariffs.
We welcome you to our hotels , upscale hotels that are setting new standards in the hospitality industry in budget accommodation in India. We provide you top class Facilities and Services. Here, the culture, mystique and hospitality of Indian blend with modern facilities and services to give you finest business class luxury hotels with unbeatable choice of distinctive suites and rooms, upscale amenities.
The company is managed by a board of directors, which comprises of top hoteliers and professionals with decades of experience in Hotel and Tourism industry.
Flawless attention to create an experience of living, variety of services designed to appeal business and leisure travelers including conference rooms, office supplies, broadband internet, restaurants, banquets, lounges and meeting space with unique ambience, known for superior hospitality and affordable luxury with common sense price and best value for money,


text:
The Audain Art Museum Read more [...]
Kitimat Museum & Archives
Place Category: Museums & Heritage Sites
Explore town history with the coming of Alcan's aluminum smelter in the 1950s, early valley settlement, and Haisla traditional arts and technology. Additional displays feature regional geology, flora, and fauna.
Annual Events
Summer of Adventure: July & August
During July and August the Kitimat Museum & Archives offers six weeks of children's summer programs and learn various things about local geology, culture, and animals.
Annual North West Photo Fest Exhibit: August
The Kitimat Museum & Archives holds a month-long exhibition showcasing local and regional photography, in the Upstairs Gallery. This exhibition officially opens the Annual weekend Photo Fest which features seminars, workshops and guest speakers.
Annual Christmas Gift Shop: December
Three weeks before Christmas each year, the Kitimat Museum & Archives hosts local crafters in its Upstairs Gallery for browsing and sales to the visiting public.
Related Links
Bulkley Valley Museum
Nielsen Gallery
Smithers Art Gallery & Gift Shop
House of Sim-Oi-Ghets
Museum of Northern BC
Nisga'a Museum/Hli Goothl Wilp Adokshl
Nisga'a Haida Gwaii Museum at Kay Llangaay
Dawson Creek Art Gallery


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In what was the final game of the regular season for Cane Ridge and Rhea County, the hosting Ravens took the contest by a final score of 35-14, bringing their record to 9-1, and dropping the Eagles to 5-5.
The game was well fought from both teams, but the speed of the Raven offense proved too much on a rain-soaked night.
The first quarter saw neither team accomplish much offensively, but that changed in the second as the Ravens overcame a slow start to take a comfortable lead into the locker room that they would not relinquish for the remainder of the game.
Despite it not being reflected in the final score, the Eagles had a nice performance running the ball with star senior wingback Christian Simon, senior fullback Brandon Hunt, and, in one of his most impressive rushing games of the season, junior quarterback Zack Pemberton leading the way.
Eagles' head coach Mark Pemberton tweeted Sunday, "It's Playoff Time!! Throw the regular season record out the window. It's a one game season each week."
Eagles enter the first round of the playoffs this week as a #2 seed with a rematch with Knoxville West, a #3 seed, in Evensville slated for a 7:00 kick this Friday night.


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MICHELE NORRIS, host:
From NPR News, this is All Things Considered. I'm Michele Norris.
MELISSA BLOCK, host:
And I'm Melissa Block. Now to a ruling today from the Supreme Court. The Court split five to four and ruled that when a person is wrongly arrested because of a record-keeping error, any evidence found at the time of the arrest can still be used to prosecute the defendant. NPR's Nina Totenberg explains.
NINA TOTENBERG: Nearly a century ago, the Supreme Court created a rule that excludes from trial evidence that is illegally obtained. The so-called exclusionary rule was created to ensure that there was no premium for police in violating an individual's constitutional right to be safe from unreasonable searches. Thus, in most instances if police conduct an illegal search, the evidence obtained cannot be used for a prosecution.
Critics of the rule have long lamented that because the constable errs, the criminal goes free, and three years ago the Supreme Court's four most conservative justices said they were willing to get rid of the exclusionary rule. The four, however, were one vote shy of a majority. So today there was a five-justice majority for a more modest approach undercutting one aspect of the exclusionary rule. For the first time, the Court said that when police record-keeping is erroneous, the evidence may still be used to prosecute.
The facts are these: Bennie Dean Herring had a history with an Alabama policeman named Mark Anderson. Herring had told the local DA that Anderson had been involved in the killing of a local teenager. The policeman had visited Herring trying to get him to drop the accusation. And weeks later when Herring was at the sheriff's department to retrieve his belongings from an impounded vehicle, the policeman asked the department's warrant clerk to see if there were any outstanding warrants for Herring's arrest. The answer was no.
Anderson then asked the clerk to check the neighboring county. This time the answer was yes, whereupon Officer Anderson arrested Herring, searched him, and found methamphetamine residue in his pocket and a pistol which because of Herring's previous criminal record was illegal for him to possess. Within minutes, though, it turned out that there was in fact no outstanding arrest warrant from Herring. It had been withdrawn five months earlier and the database had not been updated. So, the arrest was illegal and therefore so was the search. But could the evidence still be used against Herring?
The lower court said yes, and today the Supreme Court agreed. Writing for the five-justice majority, Chief Justice John Roberts said, in essence, that a police screw-up in record-keeping does not justify suppressing otherwise valid evidence. The exclusionary rule, he said, serves to deter deliberate reckless or grossly negligent conduct or in some cases systemic negligence. The error in this case, he said, did not rise to that level, since Officer Anderson thought he was conducting a search incident to a valid arrest warrant. Stanford law professor Pam Karlan, who represented Herring, sees the Court's ruling as limited but...
Professor PAM KARLAN (Stanford Law School): The handwriting on the wall for the future is the Supreme Court is not very committed to the exclusionary rule, and when it can find ways of getting around the exclusionary rule, there seemed to be five justices who are prepared to give the rule lip service and then whittle it down to a doorstop. And I think that's actually a characteristic, in some ways, an emerging characteristic of the Roberts court is there are a lot of areas where they are not overruling the precedents that are on the books, but they are narrowing them down so that they are, you know, to quote an old Supreme Court case, like "railroad tickets good for this train and this day only."
TOTENBERG: George Washington University law professor Stephen Saltzburg, author of a leading criminal law textbook, agrees.
Professor STEPHEN SALTZBURG (Law, George Washington University): The door is open for all arguments that police behavior, while it was mistaken or it was wrong, is not so egregious as to warrant exclusion. I think that's where we are, that the battle will be fought on how bad the police behavior was. And you see a lot of that in Chief Justice Roberts' opinion.
TOTENBERG: Joining Roberts in the majority were Justices Scalia, Thomas, Alito and Kennedy. Writing for the four dissenters, Justice Ruth Bader Ginsburg said that in the modern era of interconnected databases, there is little recourse for erroneous records except through constitutional protections. The result of today's ruling, she said, would likely be more innocent people wrongly arrested, handcuffed, humiliated, and searched. This, she said, is evocative of the unlimited search powers that so outraged the founders of the republic that they adopted the Fourth Amendment requiring judicial warrants and banning unreasonable searches. Nina Totenberg, NPR News, Washington.
Copyright © 2009 NPR. All rights reserved. Visit our website terms of use and permissions pages at www.npr.org for further information.
NPR transcripts are created on a rush deadline by Verb8tm, Inc., an NPR contractor, and produced using a proprietary transcription process developed with NPR. This text may not be in its final form and may be updated or revised in the future. Accuracy and availability may vary. The authoritative record of NPR's programming is the audio record.


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Enka singer Hanamizakura Kouki, who is actually the vocalist of visual kei band D=OUT, has announced the release of his second single for September 5th.
Wasuregasa will come out in three editions: two limited CD+DVD editions and one regular CD-only type. All three will feature the title track, the B-sides Bara no itsuwari and Donna kotoba yori dakishimete as well as their respective karaoke versions. Together with the above-mentioned tracks, the regular type also features an exclusive song titled Tokyo ondo 2018 ~Ouka ranbu ver~.
The DVD included with Limited Edition A features the music video and making-of footage for Wasuregasa, while Limited Edition B's DVD comes with digest footage of an acoustic set of four songs, including his debut song I love Tokyo, instead.
Wasuregasa follows his debut single I love Tokyo, which was released in February 2015.
Below, you can watch a 30-second spot for Wasuregasa:
New Single from Hanamizakura Kouki
news - 07.15.2018 13:15
source: OHP
© 2015 Tokuma Japan Communications CO., all rights reserved.


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Random pics
Kasey and Jess's halloween costumes. Ninja turtles
P.J day in school (pjamas)
Everyone knows that I love turkey, so this was my last dinner before I moved
Last day of October
Go Raiders!!!!
I can't believe it
My weekend was awesome!
Men, du far ha en underbar dag idag ocksa da. Du ar varldens gulligaste farfar. Jag alskar dig!! ♥
Min nya vardsyster Jessica gjorde en film till dig
Choir performance
I cutted my hair yesterday to. It's so much cheeper here in the States, even cutting hair.
Here is some pictures from choir. And grandpa (Stig), I have a surprice for you later today. I was supposed to put it on my blog earlier, but I didn't get the intenet to work.
Me and my choir teacher (Mrs. H)
Me, Norah, Klara and Katie
Carson, me, Norah and Klara
Alyssa, me, Noah and Klara
Todays plans
Hey again!
I'm having journalism right now and I'm doing nothing. This week is as I said a dress-up week. There's a dress-code for everyday. Today is red, but not very many people remembered that since we had a day off yesterday. Tomorrow anyway is P.J day, everyone will go dressed in their pjamas. I'll bring my camera and if a lot of people get in to it, I'll take pictures and show you what it looks like.
Today after school a photographer is comming to our house, so we'll be photographed. And in the evening Jess's having volleyboll.
Well, I gotta go now. Have a good day! ♥
Shopping in Indy
Långt svar till en fråga om kulturskillnad
Älskar din blogg!
Pink-day in school
Baby shower, last weekend
Random pics
Svar på 3 frågor
I'm there
Indianapolis tomorrow
I'm on Klaras computer right now since I dont have mine at the time. We are staying the night here at Tracy and Gregs house because tomorrow we are going to Indianapolis with Greg. That's gonna be awesome and we both are so excited!!!!
Greg is dropping us off at the mall (circle center - Indianapolis for you who're interested) and it's located downtown. We'll leave from here 7 in the morning, because he has to be at work early. So our plans until the mall opens is to take pictures and eat breakfast on Starbucks or something alike. It's gonna be good too!!
Well, I've gotta go now. I havn't tried to get the internet to work at Jessicas house yet, but I'll try that some day this weekend. And by the way, we're off Friday (tomorrow) and Monday next week (for fallbreak).
Have a good weekend and I'll talk to you again as soon as I can.
Svensk forklaring till vad som hander idag
Okej, det ar digital desgin igen och jag har absolut ingenting att gora. Sa jag tankte klargora lite saker. Jag har tankt att beratta detta valdigt lange nu, men jag tyckte inte det var en jattebra ide att skriva det pa engelska, och heller inte pa svenska. Men jag skriver det pa svenska nu, for annars blir det svart att forklara kommande inlagg.
Jag ska flytta idag. Jag har inga problem over huvud taget med mina vardforaldrar, men det ar tyvarr dags att flytta. Min vardmammas pappa gick bort och det ar valdigt ledsamt sa det ar for det battre att vi flyttar. Jag berattar allt i detalj senare, pa grund av olika skal.
Jag ska i alla fall flytta in hos Jessica, den andra blonda tjejen som ni sakerligen har satt pa bilder. Vi kommer ha sa sjukt kul tillsammans. Klara flyttar in hos vardan EF representant har i Versailles. Det som ar sa bra med denna flytten ar att jag inte behover borja om, byta skola och allt sant dar. Det hade varit rattsa jobbigt. Visst, om det hade varit till en storstad hade det varit ballt, men den chansen ar sa liten.
Okej, jag vet inte vart jag slutade nu, eller om detta blev rorigt for jag sitter och snackar med mina kompisar och den forsatter skriva osv. Vet inte om detta klargjorde nagot over huvud taget. Men det viktigaste ar i alla fall att jag flyttar idag. Jag vet inte om jag kommer ha internet (men forhoppningsvis). Jag har INGA problem med min familj, jag gillar dom sa mycket och vi kommer fortsatta traffas massa. Det ar ett maste! Och Klara flyttar in till en annan, alltsa vi skilljs at. Detta har jag heller inga problem med, hon kommer bo tva kvarter ner och jag flyttar in med Jessica som ocksa ar en senior. Hade en bild pa mig och henne for tva inlagg sen. Se har.
Nej nu maste jag dra. Jag har inget mer att skriva. Har ni fragor, kommentera sa ska jag svara. For mig ar allt sjalvklart men det ar det formodligen inte for er.
Journalism again
Another day in journalism. I should start writing my stories, but I don't feel inspired at all. This week I'm gonna have a lot of articles and pictures. Or, not a lot, but two. One about Swedish sports (so Erik, if you read this, you'll be in our school papers), and one about Swedish fashion. All boys and girls (my age) that reads my blog, please send me a picture of an outfit. A styled one with jewellry and all that. Boys is more important, because I have less outfits from them. So please, send it on Facebook or on my mail.
Well, gotta go now! Talk to you later.
Photo shoot
This is why
I am in school right now, having journalism. I found some pictures that I think you'd like to see so I'll post them too.
This weekend, Luke and Justin was here and we had a lot of fun. We hanged out at grandmas, home and we also went to a babyshower. We spent most of the time with our family here this weekend though.
The babyshower was a new experience for me. It's a friend from school who's pregnant. Yeah, from high school, so it's almost like "16 years and pregnant" on MTV. No, not really, but she's a senior here in school (my age).
Well, I have to go now. I'll try to give you another update my last period (2-3 american time/20-21 swedish). If you want to skype with me you have to log on that time. I think I'll be able to, not 100 % yet, but I might. Hopefully!!
Pumpkin Show candidate walkthrough
Jessica and I (she has my clothes, and I have her's)
Our journalism-class
Sunday, and a lot of plans
Pizza in the States
Time for a nap
Fridays outfit
Digital Design, again
I'm still finished with everything in this class and everyone else (almost) is still working. In 2 weeks, we'll start to work in Photoshop which I'm excited for. I think that will be so much more fun!
I read your comment Julia, and thanks. I'm having a great time but of course I miss you too. You are my gullunge and you know that. I miss everyone, all of my friends in Sweden, but I'm not homesick at all to be honest. I'm doing something all the time here, and when I'm not, I just feel to relax for a bit. We need that too, actually.
Here is a picture. My teacher said that I can explore "Mesh Tool", so I did... for like 1 minute. No, okey, I'll get back to "work" now. Have a nice day and I'll talk to you later again.
I love my family
This is what we are doing. On the last picture, the limegreen is from marking the same fill color to change the pictures outlook.
Some of my new clothes
Try to smile in the morning
Boot country
Kings Island
Blueberry ice-cream
Pictures from this and last weekend
About my weekend
Since I havn't blogged for all weekend I have a lot to tell. I had so much fun!
Last Friday I was sick. I was home from school and did nothing but sleep and eat. It was so boring but I guess I needed it. Tracy woke me up a couple of times to check on me, but every time I just fell back to sleep again.
I don't know what I had. It hurted in my head (felt like it was going to explode) and in my ears and eyes. The same evening I got a high fever (I don't know what high is because it was in fahrenheits haha). Anyway, I took some antibiotics and something else and fell asleap. It's wierd to take that, everyone here treats it as it's nothing special if you complare with what we have to do to get one dose of it in Sweden.
The next day was the day of excitment. We were suppose to go to Kings Island, which is kind of the same as Liseberg. I was really excited about this before I got sick, but I still wanted to go. That's a big risk to take though, because after all the roller coster, it might be a lot worse than before.
I decided to go and I don't regret that for a second. It became worse and worse after every roller coster but it was worth it. I had so much fun and we rode some awesome rides. It was also the premiere of the haunted-houses (we would say horror-houses I think). Anyway, i was so scared walking through them, but it was so fun at the same time.
We also rode the drop-zone which is kind of like "uppskjutet", but 300 feet (90 m) instead of 60 or something like that. It feels so good when the thing release from the top and you just drops down real fast. You cant even breath on the way down. That's a good feeling.
Then it was time to go home and that night I went to bed around half past 3. I was lucky though, because I didn't have to go to church the next day. That wouldn't be a good combo, of feeling bad, to less sleep and a full day at Kings Island (=wore out).
The next day, Sunday, Caleb woke be up around 12. After that we went to a cowboot store and Caleb baught some boots. I tried to find some but I didn't. I will keep looking though, cause I have the perfect ones in my head. I doubt I'll find them but I'll try. I don't want them to look like real cowgirl shoes, like exstream ones. I just want them to look like normal boots but you can sense the cowboy design haha. How hard is that to explain in English? I hope you get it.
As you see I had a lot to do this weekend. I actually didn't have the time to update you guys, eventhough I was halfway done with some posts at some times, but then we had to do something. So I tried! I took pictures though, and I'll show you all of them when I come home.
Today I have to do a lot of homeworks and boring stuff like that. But somedays has to be like that when you normally just don't do what you are supposed to. We dont have a hole lot, but we have some. For example, I'm supposed to have read 2 books next Monday. I'm also suppose to finish English Vocab, History Vocab, English assignment and I guess some Math. I have a Math-test today by the way. Wish me luck!
Well, that's all for now. I'll give you the pictures when I come home this afternoon. Have a great afternoon Sweden, and a good day America.
Best cook!
Blue hair and feathers
Green & white day
Right now I'm having journalism which basecly is a writing-class. It's here we are writing the newspaper for school and all that, that you may have seen pictures of on my blog.
Today, I was thinking about going to the volleyball-game after school. but I think I'll go home instead. I need to talk to my parents and some friends today, and I also have to do some assignments. But at the same time, I want to go to the volleyball game. Big problems, right? I don't think we'll go.
Tomorrow is a "green and white" day in school. I don't remember why, I think it was because the soccer-team won sectionals or something like that. But I cant say it for sure. I'm excited though, but I don't have very much green. We'll see what I can find (and yes, you'll get pictures).
Okey, that's it for now. Next period is choir... I'm so not excited. You know the feeling of singing and yawning at the same time, that's how I'll feel next period.
A picture from the funeral. His favourite color was red, that's why I had a red flower in my hair, red nails and red jewellery.


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Dance of the Dolphins Needlepoint Kit - Dimensions
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The thyroid hormones, triiodothyronine (T3) and thyroxine (T4), are tyrosine-based hormones produced by the thyroid gland that are primarily responsible for regulation of metabolism. Iodine is necessary for the production of T3 and T4. A deficiency of iodine leads to decreased production of T3 and T4, enlarges the thyroid tissue and will cause the disease known as goitre. The major form of thyroid hormone in the blood is thyroxine (T4), which has a longer half-life than T3. The ratio of T4 to T3 released into the blood is roughly 20 to 1. T4is converted to the active T3 (three to four times more potent than T4) within cells by deiodinases (5'-iodinase). These are further processed by decarboxylation and deiodination to produce iodothyronamine (T1a) and thyronamine (T0a).
Both T3 and T4 are used to treat thyroid hormone deficiency (hypothyroidism). They are both absorbed well by the gut, so can be given orally. Levothyroxine is the pharmaceutical name (INN) of physiological thyroxine (T4), which is metabolised more slowly than T3 and hence usually only needs once-daily administration. Natural desiccated thyroid hormones are derived from pig thyroid glands, and are a "natural" hypothyroid treatment containing 20% T3 and traces of T2, T1 and calcitonin. Also available are synthetic combinations of T3/T4 in different ratios (such as liotrix) and pure-T3 medications (INN: liothyronine). Levothyroxine is usually the first course of treatment tried. Some patients feel they do better on desiccated thyroid hormones, however, this is based on anecdotal evidence and no clinical trials have shown any benefit over the biosynthetic forms.
Thyronamines have no medical usages yet, though their use has been proposed for controlled induction of hypothermia, which causes thebrainto enter a protective cycle, useful in preventing damage during ischemic shock.
Synthetic thyroxine was first successfully produced by Charles Robert Harington and George Barger in 1926.
Today most patients are treated with levothyroxine, or a similar synthetic thyroid hormone. However, natural thyroid hormone supplements from the dried thyroids of animals are still available. Natural thyroid hormones have become less popular, due to evidence that varying hormone concentrations in the thyroids of animals before they are slaughtered leads to inconsistent potency and stability. Levothyroxine contains T4 only and is therefore largely ineffective for patients unable to convert T4 to T3. These patients may choose to take natural thyroid hormone as it contains a mixture of T4 and T3, or alternatively supplement with a synthetic T3 treatment. In these cases, synthetic liothyronine is preferred due to the potential differences between drug lots of natural thyroid products. Also it would be counterintuitive to supplement with a T4/T3 combination if the patient cannot convert T4 to T3. Some natural thyroid hormone brands are F.D.A. approved, but some are not. Thyroid hormones are generally well tolerated. Thyroid hormones are usually not dangerous for pregnant women or nursing mothers, but should be given under a doctor's supervision. In fact, if a woman who is hypothyroid is left untreated, her baby is at a higher risk for birth defects. When pregnant, a woman with a low functioning thyroid will also need to increase her dosage of thyroid hormone. One exception is that thyroid hormones may aggravate heart conditions, especially in older patients; therefore, doctors may start these patients on a lower dose & work up to avoid risk of heart attack.
Most of the thyroid hormone circulating in the blood is bound to transport proteins. Only a very small fraction of the circulating hormone is free (unbound) and biologically active, hence measuring concentrations of free thyroid hormones is of great diagnostic value.
When thyroid hormone is bound, it is not active, so the amount of free T3/T4 is what is important. For this reason, measuring total thyroxine in the blood can be misleading.
|bound to thyroxine-binding globulin (TBG)
|bound to transthyretin or "thyroxine-binding prealbumin" (TTR or TBPA)
|unbound T4 (fT4)
|unbound T3 (fT3)
T3 and T4 cross the cell membrane easily as they are lipophilic molecules, and function via a well-studied set of nuclear receptors in the nucleus of the cell, the thyroid hormone receptors.
T1a and T0a are positively charged and do not cross the membrane; they are believed to function via the trace amine-associated receptor TAAR1 (TAR1, TA1), a G-protein-coupled receptor located in the cell membrane.
Another critical diagnostic tool is measurement of the amount of thyroid-stimulating hormone (TSH) that is present.
Contrary to common belief, thyroid hormones can not traverse cell membranes in a passive manner like other lipophilic substances. The iodine in o-position makes the phenolic OH-group more acidic, resulting in a negative charge at physiolocical pH. However, at least 10 different active, energy dependent and genetic regulated iodothyronine transporters have been identified in humans. They guarantee that intracellular levels of thyroid hormones are higher than in blood plasma or interstitial fluids.
Little is known about intracellular kinetics of thyroid hormones. However, recently it could be demonstrated that the crystallin CRYM binds 3,5,3′-triiodothyronine in vivo.
The thyronines act on nearly every cell in the body. They act to increase the basal metabolic rate, affect protein synthesis, help regulate long bone growth (synergy with growth hormone) and neuronal maturation, and increase the body's sensitivity to catecholamines (such as adrenaline) by permissiveness. The thyroid hormones are essential to proper development and differentiation of all cells of the human body. These hormones also regulate protein, fat, and carbohydrate metabolism, affecting how human cells use energetic compounds. They also stimulate vitamin metabolism. Numerous physiological and pathological stimuli influence thyroid hormone synthesis.
Thyroid hormone leads to heat generation in humans. However, the thyronamines function via some unknown mechanism to inhibit neuronal activity; this plays an important role in the hibernation cycles of mammals and the moulting behaviour ofbirds. One effect of administering the thyronamines is a severe drop in body temperature.
Both excess and deficiency of thyroxine can cause disorders.
Preterm births can suffer neurodevelopmental disorders due to lack of maternal thyroid hormones, at a time when their own thyroid is unable to meet their postnatal needs.
Thyroxine and triiodothyronine can be measured as free thyroxine and free triiodothyronine, which are indicators of thyroxine and triiodothyronine activities in the body. They can also be measured as total thyroxine and total triiodothyronine, which also depend on the thyroxine and triiodothyronine that is bound to thyroxine-binding globulin. A related parameter is the free thyroxine index, which is total thyroxine multiplied by thyroid hormone uptake, which, in turn, is a measure of the unbound thyroxine-binding globulins.
Thyroid hormones (T4 and T3) are produced by the follicular cells of the thyroid gland and are regulated byTSH made by the thyrotrophs of the anterior pituitary gland. Because the effects of T4 in vivo are mediated via T3 (T4 is converted to T3 in target tissues), T3 is 3- to 5- fold more active than T4.
Thyroxine (3,5,3',5'-tetraiodothyronine) is produced by follicular cells of the thyroid gland. It is produced as the precursor thyroglobulin (this is not the same as TBG), which is cleaved by enzymes to produce active T4.
Thyroxine is produced by attaching iodine atoms to the ring structures of tyrosine molecules. Thyroxine (T4) contains four iodine atoms. Triiodothyronine (T3) is identical to T4, but it has one less iodine atom per molecule.
Iodide is actively absorbed from the bloodstream by a process called iodide trapping. In this process,sodium is cotransported with iodide from the basolateral side of the membrane into the cell and then concentrated in the thyroid follicles to about thirty times its concentration in the blood. Via a reaction with the enzyme thyroperoxidase, iodine is bound to tyrosine residues in the thyroglobulin molecules, formingmonoiodotyrosine (MIT) and diiodotyrosine (DIT). Linking two moieties of DIT produces thyroxine. Combining one particle of MIT and one particle of DIT produces triiodothyronine.
Proteases digest iodinated thyroglobulin, releasing the hormones T4 and T3, the biologically active agents central to metabolic regulation.
Thyroxine is believed to be a prohormone and a reservoir for the most active and main thyroid hormone T3. T4 is converted as required in the tissues by iodothyronine deiodinase. Deficiency of deiodinase can mimic an iodine deficiency. T3 is more active than T4 and is the final form of the hormone, though it is present in less quantity than T4.
Thyrotropin-releasing hormone (TRH) and thyroid-stimulating hormone (TSH) start being secreted from the fetal hypothalamus and pituitary at 18-20 weeks of gestation, and fetal production of thyroxine (T4) reach a clinically significant level at 18–20 weeks. Fetal triiodothyronine (T3) remains low (less than 15 ng/dL) until 30 weeks of gestation, and increases to 50 ng/dL at term. Fetal self-sufficiency of thyroid hormones protects the fetus against e.g. brain development abnormalities caused by maternal hypothyroidism.
If there is a deficiency of dietary iodine, the thyroid will not be able to make thyroid hormone. The lack of thyroid hormone will lead to decreased negative feedback on the pituitary, leading to increased production of thyroid-stimulating hormone, which causes the thyroid to enlarge (goiter)endemic colloid goiter. This has the effect of increasing the thyroid's ability to trap more iodide, compensating for the iodine deficiency and allowing it to produce adequate amounts of thyroid hormone.
Iodine uptake against a concentration gradient is mediated by a sodium-iodine symporter and is linked to a sodium-potassium ATPase. Perchlorate and thiocyanate are drugs that can compete with iodine at this point. Compounds such as goitrin can reduce thyroid hormone production by interfering with iodine oxidation.
There are no herbs (plant chemicals) that contain thyroid hormone. Therefore, while there are some herbs that may provide some help for a sluggish thyroid (i.e. if the thyroid is producing a low amount of thyroid hormone, but has not stopped completely), myxedema requires treatment with synthetic or desiccated natural thyroid hormones.However, there are many edible plants that have high concentrations of iodine (e.g., seaweed and kelp). Iodine is an irreplaceable precursor to the biosynthesis of thyroid hormones.
Thyroid hormone treatment in thyroid disease
Thyroxine-binding proteins is a protein which binds thyroid hormone. Examples include:
Thyroxine-binding globulin (TBG) binds thyroid hormone in circulation. It is one of three proteins (along with transthyretinand albumin) responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. Of these three proteins, TBG has the highest affinity for T4 and T3, but is present in the lowest concentration. Despite its low concentration, TBG carries the majority of T4 in the blood. Due to the very low concentration of T4 & T3 in the blood, TBG is rarely more than 25% saturated with its ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. TBG is synthesized primarily in the liver as a 54 kDa protein. In terms of genomics, TBG is a serpin; however, it has no inhibitory function like many other members of this class of proteins.
TBG tests are sometimes used in finding the reason for elevated or diminished levels of thyroid hormone. This is done by measuring resin binding to labeled thyroid hormone, which happens only when the labeled thyroid hormone is free.
The patient's serum is mixed with the labeled thyroid hormone; then, the resin is added to the whole mixture to measure the amount of free labeled thyroid hormone. So, for instance, if the patient is truly hypothyroid, and TBG levels are normal, then there are many sites open for binding on the TBG, since the total thyroid hormone level is low. Therefore, when the labeled hormone is added, it will bind mostly to the TBG, leaving little of it left for binding to the resin. In contrast, however, if the patient is truly hyperthyroid, and TBG levels are normal, the patient's endogenous hormone will saturate the TBG binding sites more, leaving less room for the labeled hormone, which allows greater binding to the resin.
In the situations described above, TBG testing is not very useful. However, if total thyroid hormone levels point to hypothyroidism or hyperthyroidism in the absence of accompanying symptoms, the utility of TBG testing becomes more evident, since TBG production can be modified by other factors such as estrogen levels, corticosteroid levels, or liver failure. If, for example, the TBG level is high, which can occur when estrogen levels are high, the TBG will bind more thyroid hormone, decreasing the free hormone available in the blood, which leads to stimulation of TSH, and the production of more thyroid hormone. In this case, the total thyroid hormone level will be high. And so, when labeled hormone is added, since TBG is so high, it will bind to the TBG, leaving little free labeled hormone for uptake into the resin. On the converse, in the presence of corticosteroids, which lower TBG levels, the total thyroid hormone (bound and free) in the blood will be low. Thus, when the labeled hormone is added, since so little TBG is available in the blood, only a small portion of it will bind, leaving plenty available for uptake by the resin.
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December, 2015
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Posted by: Admin | December 8, 2015
The 3 Magical M's of Marketing, part 3
This month we continue our look at the Three Magical M's of Marketing. For the past two months we examined the first two Key Elements that you must carefully consider to be successful with your marketing; 'Use the Right Media' and 'Create the Right Message'. This month we will continueRead More …
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Pro Circuit Round-up:
Rybakov, Townsend defend titles
Sally Milano | June 18, 2018
Taylor Townsend captured her ninth career USTA Pro Circuit singles title in Sumter, S.C., without having to step foot on the court, and Alex Rybakov claimed his second pro singles championship in Buffalo, N.Y., in a shortened match, as both players successfully defended their titles in the 2018 editions of the tournaments held last week.
Townsend, the top seed in the Palmetto Pro Open in Sumter, was to face No. 2 Alize Lim in the final, however Lim withdrew just before the scheduled start of the match with a back injury, giving Townsend the ninth singles title of her career.
"I have never had something like this happen in my career," Townsend said. "I completely understand, though, that Alize has to take care of her body in order to get healthy and play again this season."
Townsend advanced to the final without dropping a set after surviving an opening-round, 7-5, 7-6 (7) challenge from Australia's Astra Sharma.
She went on to defeat Americans Anastasia Nefedova, 6-1, 6-1, in the second round, No. 6 Maria Mateas, 7-5, 6-3, in the quarterfinals and Gail Brodsky, 6-2, 7-6 (4), in the semifinals before reaching the final.
The 21-year-old Chicago native has had a red-hot spring, winning two titles in three weeks at the $80,000 events in Dothan, Ala., and Charleston, S.C., and reaching semifinals at the $60,000 events in Indian Harbour Beach, Fla., and Charlottesville, Va.
Her wins in Dothan and Charleston catapulted her into first place in the USTA French Open Wild Card Challenge, giving her a wild card into the 2018 French Open, where she won her first-round match against Myrtille Georges before falling to eventual champion Simona Halep in the second round.
Townsend is now ranked No. 75 in the WTA rankings, just four spots below her career-high mark of No. 71 that she reached in May.
Rybakov (pictured above) claimed his second straight singles title at the Sargent & Collins, LLP Men's $25,000 Futures in Buffalo Sunday, after his opponent, No. 4 seed Deiton Baughman, retired in the second set of their match with the score at 7-6 (5), 3-1.
Rybakov, seeded fifth, easily won his first two matches and then pulled out a 6-7 (4), 7-6 (3), 6-3 comeback win over Mateo Martinez of Argentina in the quarterfinals. He had not played a pro match singles January, when he reached the quarterfinals at the $25,000 Futures in Long Beach, Calif.
Rybakov won his first pro singles title last year in Buffalo. The 21-year-old lefty recently completed his junior season at TCU, where he went 19-6 in singles as the team's captain and led the Horned Frogs to their third straight Big 12 regular-season title.
Other results of Americans competing last week on the USTA and ITF pro circuits include:
- Michael Redlicki finished runner-up in singles at the $25,000 USTA Pro Circuit event in Winston-Salem, N.C. Alexander Ritschard reached the semifinals, while Brian Shi and Yuval Solomon advanced to the quarterfinals. Ronnie Schneider and Trevor Johnson teamed together to reach the doubles final.
- John-Paul Fruttero was a doubles finalist at the $15,000 ITF Futures event in Gyeongsan, Korea.
- Sumit Sarkar was a singles finalist at the $15,000 ITF Futures event in Martos, Spain.
- Emmett Ward reached the singles quarterfinals, and Jordan Parker reached the doubles final at the $15,000 ITF Futures event in Harare, Zimbabwe.
- In other Sumter singles action, Ashley Lahey reached the semifinals, and Robin Anderson and Hailey Baptiste advanced to the quarterfinals. In doubles, Julia Elbaba reached the final.
- Jessica Ho won the doubles title at the $25,000 ITF Pro Circuit event in Barcelona, Spain.
- Hanna Chang won the singles title at the $15,000 ITF Pro Circuit event in Gyeongsan, Korea.
- Nick Taylor was the quad singles and doubles champion at the VINCI Wheelchair Czech Open ITF 2 Series in Prostejov, Czech Republic.
- Dana Mathewson reached the singles final and doubles semifinals in the Women's Open division at the Toyota Open International de L'ile de Re - ITF 1 in France. In the Quad Open division, Bryan Barten reached the singles semifinals and doubles final, Greg Hasterok advanced to the singles quarterfinals and doubles semifinals, and Steve Baxter reached the singles and doubles quarterfinals.
- Casey Ratzlaff was the singles and doubles champion in the Men's Open division at the Windsor Classic - ITF Futures Series in Windsor, Canada. Conner Stroud reached the singles final and doubles semifinals at the event, while Chris Herman advanced to the singles and doubles semifinals. On the women's side, Emmy Kaiser won the singles title, and Joanna Nieh finished runner-up.


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Newseum > Events > Panel Discussion > Global Trends: Paradox of Progress
Industrial and information age achievements are shaping a world both more dangerous and richer with opportunity. Human choices will determine whether promise or peril prevails.
Global Trends is the Intelligence Community's major assessment of the forces — and choices — shaping the world over the next two decades. Unique among intelligence products of this depth and stature, the National Intelligence Council's quadrennial Global Trends report is completely unclassified.
National Intelligence Council's latest edition of the report, Global Trends "Paradox of Progress" will be released Jan. 9, 2017, exploring trends and scenarios over the next 20 years.
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Have you ever had difficulty remembering an event that happened? Certain details seem fuzzy. You might start out a conversation recollecting an event in perfect detail but by the end of the conversation the person you are talking to has managed to change your perspective of what "really" happened.
It constantly happened in the organization. At first, you might not be aware it was happening. If you were newer, you felt you were subject to making mistakes or not quite understanding the situation. You quickly learned to accept the criticism and correction of your ordinates. You trusted them implicitly. They were, after all, the leaders of the movement. Questioning was discouraged, but when it happened you were re-educated.
If you hear it over and over again, you feel it must be true. If you say something over and over again, you believe it must be true.
Such repetition is constant. It starts with the basic pitches or spiels you use while engaged in the various organizing activities. You go out on a bucket drive and your most important tool is your written pitch. Same with phone calling, speaking engagements, any activity. As you develop your skills, you learn to deliver the pitch without use of the written spiel for you have it memorized. You can adapt it to a particular situation. If someone raises a question, you can cite sections from other pitches or presentations flawlessly. It included the written pitches or briefings.
Sooner or later you would run into a contradiction. Maybe you began to realize that a tuberculosis epidemic could not be really happening, for if it was then the CDC would have stepped in a long time ago to close down the farm labor camps. They could not just let that pass. You listen as the organizer explains that due to the migratory nature of the population, the CDC is ill-equipped to track the migrations. Farm workers will move on before the CDC can move in, either on their own or at the behest of their crew chiefs. It seems to make sense. Then you hear it again at a local National Labor College presentation. You hear it from other organizers and volunteers.
It did not have to be limited to aspects of organizing. Persons in leadership positions had to maintain firm control of their ordinates. If something happened that in their eyes appeared problematic, no matter how professional the person came across or no matter how upset the person appeared, their goal was to get you to believe their perspective of what really happened.
I remember one incident, but it is hazy in my mind. I was throwing up and had diarrhea. I figured it was the stomach flu or something. Two cadres came to talk to me for almost three hours. By the end of the discussion, I was convinced that I was sick because I had allowed doubt to get in the way of work, it was manifesting physically and the only solution was to get back to work. It did not matter that I sat typing traffic on the floor with a bucket next to me, for everyone else knew the problem was psychosomatic and they were there to help me work through it.
Why could it not have been the stomach flu? At the time, that was my initial question but three hours later I "knew" it was not the flu. I had doubts about the leadership that stemmed from my insecurities over the (at the time) recent arrests of several cadres. How could the organization allow comrades to be arrested? It was a temporary setback, soon to be remedied, the result of an enemy determined to destroy the organization, which meant we had to fight harder.
There comes a point when something happens, you know what really happened but others try to convince you it did not happen that way. When you dig in your heels, you endure hours of lecturing. You refuse to budge from your position. You saw one cadre hit another cadre as her way of waking up that cadre, she just hit the cadre who barely had her eyes open from the noises of reveille. They try to tell you that the sleeping cadre started hitting first but you know it did not happen like that. Then you end up in Oldie's office and he is furious with you, having heard from the operations officer that you were acting in a contrary manner.
You do not want to lie to him but you also do not want to disappoint him. It was, after all, his organization. He has more important things to deal with. You finally concede the point maybe you had missed the sleeping cadre hitting the other cadre first but it does not sit too well with you. He senses this, being very astute at sizing up people. He wants to make you feel like you are still capable of making an important contribution to the situation. Then he dictates the famous Reveille Protocol. You hear the conversations, everyone agreed the sleeping cadre hit first, you "know" you were wrong but something good came out of it.
No matter how major or minor the situation, it could be reinvented to fit the agenda of the person manipulating the other person. It was about control, after all. You might have two groups disagreeing about a particularly course of action until ultimately Oldie would come in over the top and either side with one group or put down both groups altogether in favor of his particular agenda.
Manipulating situations is not something exclusive to cults. Have you ever been at an office staff meeting listening to someone drone away about a marketing strategy? You begin thinking, "Boring!" All it takes is one exaggerated yawn, and pretty soon everyone else in the room is yawning. The speaker finally shuts up and the meeting is concluded. You have managed to take away that person's control by creating a sense that his agenda is unimportant and no one cares.
In an organization, it is important for those in leadership positions to maintain control. Even if an individual does hit upon a real problem, to discover it before a leader does causes another problem. The leader must change events such that he or she has the answers, the individual has been corrected and sees things the way the leader wants him or her to see them.


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I'm always going on and on about how to save money by joining Netflix. Why not save some money on something that will make you look good too?
Thrillist.com is running a new promo called "Cheap Gear Rundown" where they provide their readers with a ton of great promos. Check it out now – and signup for their daily e-blasts – for discounts on everything from sports inspired clothing from Amongst Friends to manly grooming from Jock Soap.
One of my favorite products from Jock Soap is Topical Storm Exfoliating Body Wash. It has a light scent and is perfect for getting rid of all that dead skin after a long day of playing ball in the scorching sun with the guys.
Click here for additional product suggestions for looking good while beating the heat.


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Hold on to your hats, it's time for the Kentucky Derby! An opportunity to celebrate Louisville, sip Mint Juleps, and for every lady to bring out her inner Southern Belle. Wondering what to wear in order to fit in at the Greatest Two Minutes in Sports? Or maybe you won't be at the track, but are headed to a classy Kentucky Derby Party. Either way, here are a handful of tips to help you out and get you looking the part, from head to toe.
Want to dress to the nines on a budget? Make your own Kentucky Derby hat!
Shoes to Spare
If you are headed to Churchill Downs, be warned, Derby Day can be a long day indeed. It is a day filled with fun and excitement, but still, it is long. So, although heels may be just the thing for your grand entrance, you may want to have something more forgiving in your bag. Trust me, you won't be the only one to switch into a low flat for an hour or two. In fact, you might even see a few people with sandals or flip flops, simply giving their Kentucky toes a break.
Yes, You Need a Hat
All you have heard is true, Kentucky Derby hats are big, wild, and ornate. Most women will have them and a lot of the men, too. Think colorful and festive when choosing a hat. And although there are plenty of opportunities to spend a bundle on your Derby accessory, you can always make your own Derby hat, too. It is a fun, celebratory tradition. Enjoy it and join in the fun without getting to hung up on the details.
Watch the Weather
Kentucky can be hot come the first Saturday in May, but then again, it can be cool. That's right, unpredictable. The warmest Kentucky Derby came in at 94 degrees in 1959, but there have been cold Derby Days, too. In 1935 and 1957, the thermometer only made it up to 47 degrees. Usually, at least over the past decade, the temperatures are normally in the 60s and 70s. Many ladies opt for a summer dress, then, if the temperatures fall, they can choose to top it with a jacket or sweater.
Be Creative
Matching your shoes, handbag, and dress is allowed and will be worn by many. But you will also see plenty of folks dressed funky! Just as the gals are donning a fabulous dress and hat, gents should suit up as well. Since the temperature may be warm, many men choose seersucker or linen.
Wondering what to wear? No problem, below are a few spots to get you started.
Want to dress to the nines on a budget? Make your own Kentucky Derby hat!


text: Well my labs did not come back great. But at least I am not anemic. They are going to put me on prescription medication to help with my high cholesterol and triglycerides. I also need to take D3 supplement which I am insufficient in. Watch carbs and sugar intake and get exercise 7 days a week. They will retest my levels in 90 days and see if I need more tests. This makes me feel old and much more out of shape than I want to feel at 37 years old. So starting tomorrow I will keep a daily health and fitness diary to see how I am doing for next 90 days. Wish me luck 🙏


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It's no secret that signing up for a travel rewards credit card is a great way to earn points and miles. From gas to groceries, almost any purchase can help you move one step closer to your dream vacation.
But better yet, why not accelerate your earning potential by adding an authorized user to your travel rewards credit card and open the door for even more savings? Plenty of travel rewards credit cards offer special perks to cardholders with more than one authorized user. Here are three benefits I think are the most worthwhile.
Bonus Points and Miles
If you're just a few points or miles short of a loyalty reward, then adding an authorized user to your travel rewards credit card may be all you need to do to reach your goal. For example, Chase Hyatt Credit Card members receive 5,000 Hyatt Gold Passport points for each authorized user they add to their account. American Express Hilton cardholders enjoyed a similar promotion this past summer that awarded 10,000 Hilton HHonors points for each new user added to the card.
Since most of these promotions last no more than a few weeks, it's important to stay on top of your favorite travel reward credit card's social media channels. At least once every few days I hop on Twitter and Facebook to see if there are any special offers coming down the pike. I also sign up for email newsletters from my favorite travel brands, so I can be fully informed on any upcoming offers – involving authorized users and otherwise.
Complimentary Airport Lounge Access
I don't know about you, but racing to the gate minutes before boarding isn't something I enjoy doing. In fact, I'll often arrive at the airport hours before my flight, giving me plenty of time to kill. Luckily, all authorized users of the Citi AAdvantage Executive World Elite MasterCard receive complimentary access to Admirals Club lounges all across the world. So rather than sitting at a crowded gate, I can make the most of my time at the airport by getting some work done or just relaxing in an Admirals Club lounge.
Yet another travel rewards credit card that offers airport lounge access to family and friends who you designate as authorized users is the Citi Prestige Card. For just $50, each authorized user will receive a Priority Pass Select membership, which includes access to Priority Pass lounges for themselves and two free guests.
Attainable Sign-up Bonuses
When it comes to attracting new cardholders, sign-up bonuses often do the trick. After all, who could turn down 25,000 free miles just for signing up? For cardholders, the real challenge comes much later. Most travel reward credit cards require members to spend a specific dollar amount during the first few months in order to earn a sign-up bonus. With authorized users, reaching such spending bonuses becomes much easier.
Say your spouse is an authorized user. Since both of you can make purchases with the travel rewards credit card, the time it takes to reach a spending bonus will be cut in half. For example, a friend of mine recently signed up for the Starwood Preferred Guest Business credit card. Earlier this year, Starwood offered two free nights to cardholders who made at least $5,000 in purchases within the first three months. Instead of trying to reach the spending goal by herself, my friend added her husband as an authorized user.
Together, they were able to spend enough to earn the free nights.
It's important to remember that as the primary cardholder, you are responsible for any and all purchases. Before signing up for a travel rewards credit card, take a few moments to consider who you might choose as an authorized user. Is the potential candidate someone you can count on? If so, then you could be well on your way to enjoying all that this additional rewards-earning strategy has to offer.


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Couture Club
LAUDED as one of the most wearable Couture Fashion Weeks in recent memory, the shows at Paris Couture Fashion Week for autumn/winter 2010-11 saw designers including Chanel, Valentino and Christian Dior present stunning collections that we could see ourselves wearing. Hair and make-up looks were equally as manageable with a focus on natural skin, and a strong lip or eye.
Find out how to wear the biggest Couture Fashion Week beauty trends here >>


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Blog Archives
Fish House in Stanley Park
Back in November of last year, we stopped by the Fish House in Stanley Park for lunch. It's been years since we last visited this restaurant located next to the tennis courts. Being a touristy spot, I was worried that it would be busy at lunchtime but I guess the rain kept everyone away because we were the first ones there (a few diners did eventually arrive a bit later).


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Unioto Beats SE to Share SVC Volleyball Title
Unioto will defend their SVC volleyball championship, needing to beat Southeastern twice this fall in order to share the crown with the Panthers at (12-2). Thursday's 25-19, 18-25, 25-21, 25-21 victory over Southeastern enabled the Shermans to overcome losses to Huntington and Zane Trace and finish as co-champs. Southeastern's only two conference losses were to Unioto, but still win their first SVC volleyball title since 1989.
After trading the first two sets, Unioto overcame third set deficits of three points at 7-4, 11-8 and 13-10 to draw even at 13-13. The set would be tied again at 18-18, 19-19 and 20-20, but Unioto never trailed at any point enroute to their pivotal 25-21 win.
The Shermans led practically the entire fourth set, although Southeastern rallied from deficits of 17-12, 18-13, but never got closer than two points the rest of the final set. The Panthers got to within 22-20, but Unioto scored 3 of the next four points for the match-win.
Unioto was powered by seniors Amanda McGlone and Jocie Fisher at the net, getting 17 and 12 kills respectively, to go with Amber Cottrill's 10 kills. McGlone also had four solo blocks to go with four assisted blocks.Hallie Pinkerton and Jocie Fisher led the defense with 16 digs, whiel Cottrill added 11.
Southeastern was led by Jess Bolte's 19 kills, Skylar Hice had 15 and Lyndsey Skeens added 9. Hice had 23 digs, Lauren Goebel 22, Lexi Lockwood 20, Holly Walsh 17 and Sierra Delong with 16 as players in double figures.
Southeastern concludes the regular season at (12-2/19-3) while the Shermans are (12-2/20-2).
Unioto 12-2 (Co-Champ)
Southeastern 12-2 (Co-Champ)
Zane Trace 9-5
Huntington 9-5
Adena 7-7
Westfall 5-9
Piketon 2-10
Paint Valley 0-14
You can hear a replay of the WKKJ broadcast with Mike Smith and Tom Beard as heard on 94 Country WKKJ, on our podcast link found below....


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The Scientific World Journal
Volume 2014, Article ID 732141, 9 pages
Research Article
Design, Synthesis, Characterization, and Computational Studies on Benzamide Substituted Mannich Bases as Novel, Potential Antibacterial Agents
M. M. College of Pharmacy, Maharishi Markandeshwar University, Mullana, Ambala, Haryana 133207, India
Received 16 August 2013; Accepted 8 October 2013; Published 19 January 2014
Academic Editors: A. Guijarro and A. Marra
Copyright © 2014 Suman Bala et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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