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Saalbach Hinterglemm Leogang Fieberbrunn
800 - 1914 m
Slope details
Ski lifts
x20 x22 x28 x1
Ski slopes
easy 149.00 km medium 110.00 km difficult 20.00 km total 279.00 km
Snow depth
Na górze: 90cm Na dole: 55cm
Weather conditions
Weather Saalbach Hinterglemm4°C -3°C 3°C Clouds Early/Clearing Late Thursday 2°C 7°C PM Light Rain Friday
The Skicircus Saalbach Hinterglemm Leogang and Fieberbrunn is growing to form the largest interconnected ski area in Austria, with an unbeatable range of winter sports on 270 km of pistes.
The Skicircus Saalbach Hinterglemm Leogang and the neighbouring Tyrolean Fieberbrunn ski area are growing together; from December 2015, there will be a new 10-seater gondola lift TirolS and a new 3.5 km Vierstadlalm piste linking the 2 ski areas. This means that from the winter season 2015/16 the expanded Skicircus will have 270 km of pistes and 70 lifts, making it not only the largest interconnected, but also one of the most varied ski areas in Austria. Both sides of the link bring with them their individual strengths, offering an unbeatable range. The present Skicircus entices especially thanks to the expansiveness of its ski area with it perfectly prepared pistes and World Cup runs, snow parks, skimovie, speed and race slopes, floodlit pistes, and snow trails, as well as an unparalleled provision of Alpine huts and the best in après-ski. Fieberbrunn is well known for its extensive freeride area that has been internationally renowned for many years.
The Skicircus in figures
The largest interconnected ski area in Austria offers winter sports fans uncompromising variety from the winter season 2015/16 with: 270 km of pistes, of which 140 km are blue, 110 km red, and 20 km black; 70 lifts, 60 cosy ski huts, 4 snowparks, 5 natural freeride parks, 2 floodlit pistes, 5 toboggan runs, skimovie, speed, and race slopes, funcross and snow trails, snowtubing, cross-country trails, and more besides. In addition to all this, there is a range of further activities including Snowmobil-City, Flying Fox XXL, and the treetop walk.
The Region
Saalbach Hinterglemm is situated in the province of Salzburgerland close to the German border. In summer the resort is transformed into a well known area for families, bikers and hikers. During winter, the resort is one of the largest and most modern ski areas in the alps. Framed by the rolling hills of the Pinzgauer grass mountains as well as the imposing peaks of the Kitzbühler alps, Saalbach Hinterglemm is an ideal Winter sport destination for many activities in the great outdoors. Skiing, snowboarding, cross country, as well as snow shoeing and winter walking. At every level only the best developed infrastructure can be expected.
The resort of Saalbach Hinterglemm is situated in the Glemm Valley and can be reached from one side only. At the Talschluss (end of the valley) visitors will find an exciting world of adventure in a natural environment amidst the mountains. For adventure, aside the piste, there are so many possibilities with huts and guest houses catering for the needs of the more mature and young alike. For accommdation, guests can choose from a large selection of different types of lodging. Whether it be a cosy alpine hut, a comfortable hotel room, modern apartment or reasonable priced youth hostel:
Saalbach Hinterglemm has something to suit all tastes and pockets!
|Ski pass category
|1 Day (2016-2017)
|26,00 €
|39,00 €
|52,00 €
|52,00 €
|2 Days
|51,50 €
|76,50 €
|101,50 €
|101,50 €
|3 Days
|72,50 €
|109,00 €
|145,00 €
|145,00 €
|4 Days
|92,00 €
|137,50 €
|183,50 €
|183,50 €
|5 Days
|107,50 €
|161,00 €
|214,50 €
|214,50 €
|6 Days
|125,00 €
|187,50 €
|250,00 €
|250,00 €
Notes prices
*Prices shown in "low season" correspond to the "pre season" (03.12. - 18.12.2015)!
*Children: born 2000 - 2009
*Youth: born 1997 - 1999
For all ages an official photo ID is required
Opening hours
Monday: 08:30 - 16:30 Tuesday: 08:30 - 16:30 Wednesday: 08:30 - 16:30 Thursday: 08:30 - 16:30 Friday: 08:30 - 16:30 Saturday: 08:30 - 16:30 Sunday: 08:30 - 16:30
Season: 2016-12-24 - 2017-03-17


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Ms. Hoots has worked as an engineer supporting new product manufacturing, distribution and repair processes for over 15 years. The last ten years of her career she has worked in HP's Americas Environmental Compliance organization. In this organization, she has been involved with understanding the recyclability of HP products and the affect new regulations have on product design. She currently helps ensure HP products meet or exceed environmental regulation requirements and works with legislators and industry associations so that they understand the impact environmental regulations can have on the environment.
Additionally, Ms. Hoots has been certified in production and inventory management with APICS, the Association of Operations Management since 1990. She teaches Supply Chain management classes for APICS and is currently the VP of Education for the local APICS Sacramento chapter.
Ms. Hoots resides in Roseville, California with her husband, her three kids, and her animals on a Christmas tree farm. In her spare time, she enjoys being outside with her kids and tending to her Christmas trees.
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subset: commoncrawl


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Getting There -- Navajo National Monument can be reached by taking U.S. 89 N. to U.S. 160 to Ariz. 564 N.
Fees -- Monument admission is free.
Visitor Information -- For information, contact Navajo National Monument, HC 71 Box 3, Tonalea, AZ 86044 (tel. 928/672-2700; www.nps.gov/nava). Late May through mid-September, the visitor center is open daily from 8am to 6pm; in winter the visitor center is open daily from 9am to 5pm. The monument is open daily from sunrise to sunset.
Note: This information was accurate when it was published, but can change without notice. Please be sure to confirm all rates and details directly with the companies in question before planning your trip.


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Inspiration connection workshopOn Sunday May 12th 2019. This inspiration workshop will cover connection with your guides through inspiration writing and speaking in the morning. In the afternoon we will extend this connection through art, looking a psychic art and messages that come come from drawings.
Sharon medium and Chris a spiritual artist from Bengalrose is running this wonderful workshop Bettws in Bloom, 1 Lambourne Way, NP20 7TL, Newport. Pre-booking and payment is essential as spaces are limtied. Please cancellation rules on www.bengalrose.co.uk workshops.
Please bring a packed lunch and the workshop is £40, please contact Sharon to book your space.
Sunday May 12th 2019.
£40 per person
You will link to your guides:
- Work on building you power and connection to your guides and beyond
- You will be inspired by words, thoughts and the wisdom of spirit
- Your creative flair will be tapped into to help you bring forward message form the spirit world in a new way you never imagined


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Monday, April 5, 2010
Posted by Linda McCoy at 10:46 AM
Labels: Pet Portrait
1 comment:
Nice guide! thank you!/I love it ! Very creative ! That's actually really cool Thanks.ReplyDelete
Pet Portraits
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My fine art pet portraits will capture your special animal companion's unique personality and likeness. I try to portray your pet's physical appearance as well as their essence and spirit that you love so much. Each portrait is hand painted in oil (from your favorite photo or a photo I take of your pet) on stretched canvas in a realistic style that will reflect your pet accurately and beautifully.Check out my webpage also at www.artwithlindamccoy.com
Nice guide! thank you!/I love it ! Very creative ! That's actually really cool Thanks.
Pet Portraits


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Grace's new medication arrived today from Holland, it's called Vigabatrin and is not currently available in the US as of yet and the FDA has yet to approve.
We will make dosage increases over the next month. She starts at 250mg at bedtime for one week, then 250mg twice a day, then 500mg twice a day, and finally 750mg twice a day. We should know if Vigabatrin is going to work within a month.
I've been feeling this come on let's go anticipation about starting Vigabatrin, but now that it is here and Grace has received her first dosage it's more of a holy crap what if this doesn't work feeling.


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Yes!! FREE SHIPPING offer on this product extended to 31st May 2019
12ft Replacement Trampoline Net- Inside Net Design
Keep the kids safe with the Up-Shot 12ft Replacement Net . Made with quality anti-graze mesh for superior safety and durability. For additional safety Up-Shot net includes a double-lock zip-and-clip entry system . Suitable for trampolines with inside net design. Order your Up-Shot 12ft Replacement Net today!
- Anti-graze mesh
- Enclosed safety netting
- Safe double-lock zip-and-clip entry
- For inside net trampoline designs
- Number of Net Poles: 8
- Entrance System: Dual secure Clip n' Zip
- Safety Net: Reinforced polyethylene
- Carton Weight: 2.6kg
- Carton Dimensions (W x D x H): 68 x 35 x 14cm
Package Includes:
- 1x Up-Shot 12ft Replacement Net
Add this to your cart today, and pay over time with your choice of Afterpay, zipPay or LayBuy!


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- paraben, sulfate, phthalate, phosphate & gluten free. cruelty free. vegan.
- recyclable packaging.
- made in the u.s.a
Welcome to Donna's Fashions!
this large slow-burning candle is crafted with an all-natural proprietary blend of soy, palm and coconut wax and will fill the room with the aura of kai's intoxicating scent. 10 oz
8 in stock
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text: I came here with a discount coupon. I heard it was expensive, so I thought this was a good time to try this place. Everything was certainly overpriced, especially the tiny bottles of sake. The food is very good, but for the price I'd have rather had something a little more memorable, or a larger portion. I tried it, it was fine, but probably wont be back. I'll stick to Nanami or some smaller local places. If you do go, try the beef bulgogi or the heart attack roll. Skip the miso. It's bland.


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So, I did it! Alongside commuting to London every day, I spent 7 weeks at the end of last year taking an online course about depression through Coursera.org. Coursera lets you take university modules for free in LOADS (and I really mean LOADS) of different subjects. Mine was from the US, but you can also study from Russian, Chinese, German…all kinds of universities.
Why did I decide to do this? I have a number of people in my life who suffer with depression. Having depression sucks, but also having a loved one with depression sucks (arguably) just as much, so in an effort to help, I decided to learn a little more. If I can train to be a depression counsellor, that would be great. But that's both very time consuming and also very expensive so that's not on my horizon just yet.
I learnt so much on the course, and it was really full-on, especially alongside a full-time job. But these are the things that really stood out in my mind as I studied:
Depression and Diabetes are Linked
There is a strong link between depression and diabetes, with each one potentially causing the other.
"The women on antidepressant medications had a 25% higher risk of developing diabetes compared to those without depression." Source
There isn't enough known at this point into how they affect each other, but this is just one more sad item to add to the list of dangers when a person falls into depression (others being loss/gain in weight, stomach issues, suicide and many more).
A Good Lifestyle Can Help
There are some things that can really help fight depression – two of which are a healthy diet and lots of walking. Fitness in general is good for someone suffering with depression, but walks can help clear the mind of clutter, fighting the depression demons.
Different Cultures see Depression Differently
One of the most interesting things I learnt was how different people view depression.
There was a study of African cultures wherein they monitored people with depression. So, they went to all these different groups of people and said "can you show us a few people who have depression?" And the people said "oh depression! You mean tummy aches!" and then some other people said "depression? Oh, person-weakness!" and "ah! Sleepless disease!" They didn't see depression as the same thing that we see it as – as something that makes you very sad, but as something with different symptoms. Which makes sense, as depression is such a multi-faceted disease.
This is a very long study that looks into all kinds of things like this.
The biggest Cause of Depression is…
If something really crap happened in your life – a death, stress, a breakup, whatever – who would you talk with? If you have someone in mind that you know you could go talk to and they would listen then you are good. If you could not think of someone who you would go to talk to, then you are at risk.
Friends are important, we all know that. But making sure you have someone to speak with regularly about things, and especially someone to turn to when things are a bit crap is vital to your mental wellbeing.
What can you do if you don't have a close friend? I know as well as anyone that making friends is bloody hard work, but it's worth it in the end. Go out there, join meetup.com, go out and find people you like and work to build friendships. If you have people around you that you like but aren't that close to, then invite them out, or even invite them round. Cook them a meal. Go see a film. I'm absolutely serious because people having close friends is the single most important thing in fighting depression.
So that's the end of my rant (haha…)
I can highly recommend the course and can't wait to learn something else on Coursera. If you could study one thing, what would you study?


text: Game Goblins is excited to host the 6th annual International TableTop Day! As always, we'll have a myriad of games available to demo, TableTop streaming on the big screen, and giveaways galore! As a retailer, we get exclusive access to all the TableTop promos that you've come to love, and our knowledgeable staff and volunteers will be on hand to answer questions (or jump in and play)!


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New in 2017, our elite Athletics development programme allows young people to develop and enhance their performance in a range of Athletic events. The athletics sessions will be led by Mrs Cann and Miss Allason, who are both UKA qualified coaches at Basildon athletics club.
Our programme is designed to provide extra support and opportunities to young athletes who show commitment and passion within Athletics. There are three sessions a week, two before school and one after which will include a range of sessions such as strength and conditioning, event specific training and general fitness and power sessions. It allows the students to develop their skills and techniques during school hours, whilst making sure they continue to progress academically.
The coaches and teachers will have very high expectations for the students involved, pushing them to achieve their potential. This will be highly demanding mentally and physically but gives the students a great start on the road to becoming a dedicated and focused athlete.
Coaches Details:
Name: Katie Allason
Role at Woodlands:
PE Teacher and Head of EPD Athletics
Coaching Qualifications:
UKA level 3 performance coach
Coaching History:
Katie has spent 8 years coaching sprints and hurdles at Basildon athletics club and was previously a competitor for the club. She is currently the Junior girls Essex AA team manager for both Athletics and Cross country.
For More Information Please Contact Miss Allason – firstname.lastname@example.com
Name: Leigh Cann
Role at Woodlands:
PE Teacher, Head of EPD Athletics and subject leader.
Coaching Qualifications:
UKA level 3 performance coach
Coaching History:
Leigh has been in involved in coaching and competing in Basildon athletics club for over 30 years. She is currently the Senior girls Essex AA team manager for both Athletics and Cross country and has previously been a team manager for the England schools AA.
For More Information Please Contact Mrs Cann – email@example.com
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Looking for mooring, playground, or decking ropes? Ropes Direct have you covered. We have a wide range of products suitable for many purposes.
We make our huge range of ropes available here on our site – and thanks to our excellent level of service we have a long list of happy customers who come back to us time and time again. But don't just take our word for it, read what they have to say on our testimonials page.
We stock a wide selection of ropes which means we are able to cater to a huge range of customers both commercial and domestic who are in search of rope for all kinds of uses.
You won't be stuck for choice of material; we stock cotton, flax, hemp, jute, manila, sisal, bungee cord, polyester, polysteel, steel wire ropes and steel chains. Each type of material is available in a number of different lengths and thicknesses. We sell both by the metre and in pre-cut coil lengths.
Our high-quality ropes are suitable for use as activity ropes i.e. rope ladders and wooden swings, in marine settings or as mooring rope, for domestic use and for any commercial application.
Selling exclusively online means we are able to save on overheads which we pass on to you, the customer, by offering fantastic prices on all our commercial and domestic ropes. Marine grade ropes, for example, are cheaper here than on dedicated chandlery websites.
You can also make even greater savings by checking our Clearance Offers regularly for discounted items.
It's so easy to finish your ropes for their particular uses with our range of accessories and extras. Pick up rope and chain fittings, ratchet load straps, rope end finishes or rope cutting knives through our shop.
We also provide gift certificates which are perfect for keen DIYers, yachters or for anyone planning to use a rope around their garden.
We operate a very quick turnaround from the point of ordering to shipping out your items. Commercial customers in mainland UK can enjoy next working day delivery on orders placed before 12pm (excluding Scottish Highlands). Orders from individuals will normally be delivered within 1-2 working days.
Delivery to anywhere in the world is available through a number of global couriers. We ask that you allow up to 2 weeks for some international deliveries.


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for booking call us on 09448693890 / 09449305090
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About UsA DAY OF EXPERIENCE IN KALYANCOOL HOMESTAY
Nestled amidst lush green coffee plantations & comfortably located at approximately 25 Kilometers from the lovely Chikmagalur city, Kalyancool Homestay is a perfect getaway from the cacophony of city life. At an elevation of 3,400 feet above the mean sea level, the air is fresh and clean. The daily din of engines revving & incessant honking is swapped by the pleasant sound of chirping by variety of birds all day long & the sound of Jewel Bug (Jeerunde) in the night.
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Room 1 to 4 Kalyancool Homestay
Room 5 & 6 (Premium Rooms)
Plantation walk !!!!Kalyancool Homestay
playing and activities area in Kalyancool Homestay
In & Around
- Mullayanagiri hill
The peak gets its name from a small temple (gadduge/tomb) at the summit, which is dedicated to a Tapasvi "Mulappa swamy" who, is believed to have meditated at the caves only a couple of feet below the summit. The caves are accessible and not very deep, they have a direct entrance to the garbagudi of the temple, which is now blocked by the temple priests.
- Baba Budangiri
The main peaks in this range are the Mullayanagiri and Baba Budangiri (height 1895 m). Collectively, these peaks are known as Chandradrona Parvatha Shreni (Chandradrona Mountain Range) as they naturally form the shape of a crescent moon. Mullayanagiri (also spelt Mullayangiri or Mullainagiri) is the highest peak in the Baba Budangiri range.
- Kallathigiri Falls
Just 10 km's away from Kemmangundi is Kallahathigiri Falls, also known as Kalahasti falls. Water cascades down from the top of the Chandra Drona hill from a height of 122 meters amidst fascinating scenery.
- Agumbe
80 Kms Agumbe is an angelic hamlet located on the top of Someshwara Ghats. It is situated between two beautiful districts Shimoga and Dakshin Kannada of Karnataka at an altitude of 2710 meters from sea level.. The dazzling place is blessed with immense forest and snow-capped high lands teemed with sublime climate.
- Bandaje Falls
Bandaje falls is located in the Charmadi Ghat, a part of Western Ghats. This fall is favorite among the trekkers as it is the junction for several trekking routes.
- Horanadu / Kalasa
15 Km's It is the major tourist attraction in the state of Karnataka. It is holy town and flocked by huge number of devotees and visitors throughout the year. The land of temples is located in the district of Chikmagalur. There are plenty of sacred shrines are located throughout Horanadu.
Kalyan Cool Homestay
Chikmagalur is a heaven for every one of those keen travelers who adore being in the hills, amidst the abundance of greenery and mystery, and making for a wonderful homestay. If coffee plantations, hills, and green slopes are what you look for in your plans, there is no other destination is perfect than Chikmagalur. In addition to this, if you desire to be pampered by relaxation, a Holiday Homes in Chikmagalur like Kalyan Cool Homestay will delineate what you can identify your own personal piece of paradise.
Kalyan Cool Homestay – A Perfect Dwelling Point
Settled in the mid of blossom green coffee plantations & happily placed at just about 25 Kilometers from the exquisite Chikmagalur city, Kalyan Cool Homestay is the perfect dwelling point from the turbulence of city life. At a stature of 3,400 feet on top of the mean sea level, the air is clean and fresh. The daily hullabaloo of vehicles & nonstop honking is switched to the pleasurable jingle of twittering by a wide range of birds daylong & the echo of Jewel Bug (Jeerunde) in the twilight.
The accommodation in Kalyan Cool Homestay is idyllically designed with the profusion of windows providing a striking vista of the nearby abundant green coffee plantation.
We acknowledge that our esteemed guests require more than just tranquil ambiance & comfy accommodation, so we welcome you to find the assortment of local Malnad delicacies of both vegetarian as well as non-vegetarian ready with organic and local ingredients & provided with the amazing hospitality from the hosts at the Best Homestay in Chikmagalur - Kalyan Cool Homestay.
With the wide spectrum of scenic day-outing locations nearby Kalyan Cool Homestay, we would be contented to assist you to plan your schedule to provide you with the most wonderful experience out of your getaway.
Accommodation & Facilities at Kalyan Cool Homestay
About staying here, this ideal Best Accommodation & Resorts in Chikmagalur near Mullayanagiri renders two distinct forms of accommodation choices. You can select to reside in the regular rooms or premium rooms. The accommodations are offered on double as well as quadruple sharing basis, shaping the homestay superb for families, group of friends and couples. Concisely, the homestay is for everyone as well as the staff, on the premises, ensure that everyone makes the most of their comfort here.
The Other Facilities Include-
- - Serve welcome drink to the guests on arrival
- - Purified aqua drinking water
- - 24hrs Hot Water
- - Complimentary Bonfire(Fire Camp)
- - Sports and activities such as Badminton, Air Gun Shooting, Cricket Volleyball
- - Indoor games like Chess and Carrom
- - Bird watching and a walk in a coffee field
- - Room serving and high security


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- Research
- Open Access
Pharmacovigilance of artemether-lumefantrine in pregnant women followed until delivery in Rwanda
© Rulisa et al.; licensee BioMed Central Ltd. 2012
- Received: 25 February 2012
- Accepted: 6 July 2012
- Published: 6 July 2012
The World Health Organization presently recommends Artemisinin-based combination therapy (ACT) as first-line therapy for uncomplicated P. falciparum malaria. Many malaria-endemic countries, including Rwanda, have adopted these treatment guidelines. The Artemisinin derivative Artemether, in combination with lumefantrine, is currently used in Rwanda for malaria during the second and third trimesters of pregnancy. Safety data on the use of ACT in pregnancy are still limited though and more data are needed.
In this pharmacovigilance study, the exposed group (pregnant women with malaria given artemether-lumefantrine), and a matched non-exposed group (pregnant women without malaria and no exposure to artemether-lumefantrine) were followed until delivery. Data were collected at public health centres all over Rwanda during acute malaria, routine antenatal visits, after hospital delivery or within 48 hours after home delivery. Information gathered from patients included routine antenatal and peri-partum data, pregnancy outcomes (abortions, stillbirths, at term delivery), congenital malformations and other adverse events through history taking and physical examination of both mothers and newborns.
The outcomes for the total sample of 2,050 women were for the treatment (n = 1,072) and control groups (n = 978) respectively: abortions: 1.3% and 0.4%; peri-natal mortality 3.7% and 2.8%; stillbirth 2.9% and 2.4%; neonatal death [less than or equal to]7 days after birth 0.5% and 0.4%; premature delivery 0.7% and 0.3%; congenital malformations 0.3% and 0.3%. A total of 129 obstetric adverse events in 127 subjects were reported (7.3% in the treatment group, 5.0% in the control group). In a multivariate regression model, obstetric complications were more frequent in the treatment group (OR (95% CI): 1.38 (0.95, 2.01)), and in primigravidae (OR (95% CI) 2.65 (1.71, 4.12) and at higher age (OR per year: 1.05 (1.01-1.09).
There were no specific safety concerns related to artemether-lumefantrine treatment for uncomplicated falciparum malaria in pregnancy. However, more obstetric complications were observed in the treatment group. These increased occurrence of complications could, however, be caused by the malaria episode itself, but further assessment is required.
- Pregnant Woman
- Malaria
- Congenital Malformation
- Falciparum Malaria
- Perinatal Mortality
Malaria poses a heavy burden of disease in many countries, especially in Africa, and contributes to at least 40% of all consultations in health centres in Rwanda [1]. In response to rising mortality from malaria, linked to increasing parasite resistance and a decrease in the efficacy of older anti-malarials, such as chloroquine and sulphadoxine-pyrimethamine (SP), the World Health Organization (WHO) now recommends the use of Artemisinin-based combination therapy (ACT) as first-line treatment of uncomplicated P. falciparum malaria [2]. Many countries, including Rwanda, have shifted their malaria treatment guidelines to using ACT as the first choice, including for pregnant women in their 2nd and 3rd trimester [3]. Artemether-lumefantrine (AL; Coartem®, Novartis) is an ACT that is very effective and well-tolerated [4, 5]. Despite the fact that AL is not registered for use during pregnancy, WHO Treatment Guidelines recommend that, in the second and third trimesters of pregnancy, only an ACT that is known to be effective in that particular country/region, should be used [2, 6]. In the first trimester, an ACT should only be used if there is no other treatment immediately available. The limited safety data continue to restrict ACT use in the first trimester, but the rapid adoption of ACT means that they may be prescribed inadvertently in early unsuspected pregnancies [2]. Uncertainty about the use of anti-malarials in pregnancy may lead to loss of public confidence in a drug and poor adherence to the treatment regimen. This may ultimately lead to treatment failure and the development of parasite resistance [2]. Further studies are required in women in all stages of pregnancy to effectively assess the risk-benefit profile of Artemisinin compounds [7].
Stringent guidelines discourage pharmaceutical companies from including pregnant women or even women of child-bearing potential in all stages of clinical trials [8]. Current guidelines for the inclusion of pregnant women in controlled trials vary from a cautious attitude of the US Food and Drug Administration (FDA) [8] to advocating the inclusion of pregnant women by the Joint United Nations Programme on HIV/AIDS (UNAIDS) (the Joint United Nations Programme on HIV/AIDS) and WHO [9].
Often, only non-clinical data are available for assessing the effects of anti-malarials during pregnancy [10]. Animal studies have shown adverse effects of the Artemisinin derivatives on early foetal development [11, 12] and they have only partly been evaluated during early pregnancy in humans [13]. A further challenge is to distinguish the potential effects of ACT from the effects of malaria in pregnancy, which include maternal anaemia, low birth weight, adverse effects on foetal development and, in low transmission areas, an increased risk of severe malaria [2]. Active monitoring of anti-malarials in pregnancy is recommended by WHO and the European Medicines Agency (EMA) [2, 10]. The WHO recommends that Pregnancy Exposure Registries be used [2], as these can monitor and record data on drug exposure and outcomes in pregnancy and may provide reassurance on the potential risks associated with anti-malarial drugs such as AL [14].
Unfortunately, the health infrastructure in many malaria endemic areas does not allow to consistently collecting data on drug-related adverse effects and data cannot be extracted from the established passive pharmacovigilance systems in industrialized countries where tropical diseases are rare and treatment and population characteristics may be different (genetics, access to healthcare, socio-economic conditions). An international anti-malarial exposure registry has been created to follow the effects of implementation of ACT in Africa; however, it has not yet been analysed for data on anti-malarials in pregnancy.
In this prospective observational study in Rwanda, a group of urban and rural pregnant women receiving AL for malaria and pregnant women without malaria and who were not exposed to AL were closely followed to determine whether adverse outcomes were more frequent after administration of AL for malaria.
Study design
This cohort study took place from June 2007–July 2009 at ten health centres in Rwanda. The treatment group consisted of women who were prescribed AL for an episode of malaria in their second and third trimester of pregnancy, according to the national Rwandan guidelines for treatment of malaria. Women could be included immediately after the decision to treat with AL for malaria had been made, hereafter called "prospective" inclusion. Women who, during antenatal clinic attendance, were found to have been treated with AL during that pregnancy could also be included "retrospectively" if treatment could be verified from the patient prescription and treatment register at the health centre. The unexposed group consisted of pregnant women with no history of previous or current treatment with AL in the existing pregnancy and without any signs or symptoms of malaria. In order to estimate gestational age last menstruation, fundal height and date of quickening were recorded and correlation of at least two of the three factors was used for the age determination. Data were collected from the following participating primary health centres and district hospitals, located in malaria-endemic regions: Muhima (Kigali), Munyaga, Rwamagana and Rubona (Rwamagana district), Rukara (Kayonza district), Bukora (Kirehe district), Karambi (Ruhango District), Busoro (Nyanza District), Mashesha (Rusizi District) and Mubuga (Karongi District). All health centres provided antenatal care for pregnant women. Data were also collected from district hospitals where study subjects were referred to for delivery. The study was approved by the Rwandan National Ethics Committee prior to commencement. Each patient gave written informed consent before entry into the study.
Study population
Exposed cohort women with malaria treated with AL
Pregnant women above the age of 18 years were included in the study if the woman was to be treated with AL after diagnosis of simple (uncomplicated) P. falciparum malaria. The diagnosis of malaria was established through a positive blood smear or based on clinical symptoms. Patients of presumed malaria, i.e. when signs and symptoms were suggestive of malaria and were accordingly treated with AL but in the absence of microscopy or rapid diagnostic tests (RDTs), were also included. Pregnancy was detected clinically or by a beta human chorionic gonadotrophin pregnancy urine test. Gestational age was verified by ultrasound in a subset of subjects. This study also tried to capture inadvertent AL treatment during the first trimester by retrospective inclusion.
Non-exposed cohort women without malaria treatment with AL
Following recruitment of a patient in the treatment group, a woman with a similar stage of pregnancy and without history of previous or current treatment with AL in the existing pregnancy was selected at the same health centre during routine attendance at the antenatal clinic and invited to participate in the study as part of the control group. These control women were confirmed as at the moment of enrolment having no malaria by a negative blood smear. Previous malaria episodes that were treated with quinine instead of AL were considered as control women as well. Initially unexposed control mothers who developed malaria and were treated with AL at any point during follow-up were thereafter considered part of the treatment group.
Study objectives and procedures
Data were collected from enrolled patients and control women upon recruitment at health centres through case report forms (CRFs). Baseline data included demographic data, number of pregnancies, gestational age, medical and obstetric examination, body temperature, malaria symptoms, usage of anti-malarials or other drugs and HIV serology. Malaria treatment response was classified as adequate clinical and parasitological response, late treatment failure (specifying late clinical and late parasitological failure) or early therapeutic failure, according to internationally accepted criteria [2].
All subjects were assigned a unique study number for recording. CRFs were filled out for exposed and non-exposed subjects during monthly antenatal clinic visits and upon any other visits to the health centre for health concerns, until delivery.
CRFs were updated with data during routine follow up after malaria or during antenatal clinic attendance, registering normal/abnormal development of the pregnancy and occurrence of symptoms suggestive of drug-related adverse events (AEs). CRFs were designed to capture adverse obstetric outcomes (abortion, peri-natal mortality, stillbirth, pre-term delivery, and unexplained neonatal death ≤7 days after birth), adverse infant outcomes (congenital malformations regardless of the pregnancy outcome, and neurological problems) and other AEs through history taking and physical examination of both mothers and newborns.
Serious AEs (SAEs), were those which resulted in death; were immediately life-threatening; resulted in persistent or significant disability/incapacity; resulted in a congenital anomaly/birth defect of the new born; required inpatient hospitalization or prolonged existing hospitalization or were deemed "important medical events" by the investigator. Serious adverse events had to be reported to the study coordinator within 24 hours after notification to the health centre.
The cause of all adverse pregnancy outcomes was investigated by structured questioning of the mother about pre-mortal symptoms to determine the likely cause of death. Women were encouraged to comment on suspected causes of these events.
Women in both groups were encouraged to deliver at the health centre with nurses' or midwife's aid, or at the district hospital, rather than to deliver at home. Women presenting to the hospital or health centre for delivery were asked about any complications experienced during the pregnancy. Following delivery, general health status was assessed in all newborns including scleral icterus, APGAR scores and prematurity. Women undergoing a home delivery were asked to bring in their newborn for medical evaluation at the health centre within 48 hours assisted by the community health care workers (not informed to which group the women belonged). A thorough physical examination was performed on the foetus by nurses/doctors trained to detect congenital defects and physical abnormalities. At follow up visits, a general assessment of the infant development (e.g. sitting unsupported, movement, lifting head) and possible defects in psychomotor and neurological development, using the WHO motor development milestones [15], was performed.
Statistical analysis
A sample size of 1,000 treated and 1,000 untreated pregnant women was needed to detect a two-fold or greater difference in the relative risk of congenital malformations in the treatment group with 80% power and 95% confidence, based on the assumption that the incidence in the general population, and thus the un-exposed control group, is 2.5%.
Standard parametric statistical tests were used for comparison of normally distributed nominal and numeric data. Non-normally distributed data were analysed with the appropriate non-parametric tests. Normality was tested with the Kolmogorov-Smirnov test and by visual checks of frequency distributions and QQ-plots. Comparison of proportions between categorical and ordered categorical variables was done with Chi-square tests or Fisher's exact tests. Statistical significance was determined at the 5% level (p < 0.05).
The associations between the main outcomes, obstetric complications and congenital malformations, were analysed in univariate and multivariate logistic regression models. Potential confounders, age of the mother, gravidity (primigravidae versus secundi- and multigravidae) and gestational age (as first trimester versus second and third trimester) were included in the model. Results were expressed as odds ratios.
Patient characteristics
Study groups
Pregnant women treated with AL for malaria (n = 1072)
Pregnant women without malaria (n = 978)
Followed prospectively at AL treatment
358 (33.4%%)
885 (90.5%)
Recruited at second AL treatment during this pregnancy
Recruited after recovery from malaria but before delivery
513 (47.9%%)
Recruited after delivery
188 (17.5%)
93 (9.5%)
Delivered during treatment
7 (0.7%)
Median age (min–max, yrs)
26.0 (17–48)
27.0 (16–47)
320 (29.9%)
210 (21.5%)
712 (66.4%)
730 (74.6%)
40 (3.7%)
38 (3.9%)
Median gravidity (min–max)
2 (1–12)
3 (1–11)
Median parity (min-max)
1 (0–10)
2 (0–9)
Mean gestational age (95% CI, weeks)
25.8 (25.3, 26.4; n = 1052)
28.5 (28.0, 29.0; n = 973)
96 (9.0%)
43 (4.4%)
434 (40.5%)
341 (34.9%)
542 (50.6%)
594 (60.7%)
Reported Medical History
1st AL treatment during this pregnancy >56 days before 2nd treatment
Quinine treatment during this pregnancy
> 56 d before AL
Just before delivery, > 56 after AL
Intermittent Presumptive Treatment with SP
242 (23.4%; n = 1032)
265 (28.2%; n = 940)
1 (0.1%)
Diabetes mellitus
1 (0.09%)
1 (0.1%)
A total of 96 women (9.0% of the treatment group) inadvertently received AL during their first trimester of pregnancy and were included in the study when this was identified during routine obstetric consultations. Some women were also recruited retrospectively after confirmation of AL treatment for malaria from the treatment register and their prescription card and henceforth followed. Miscalculation of the gestational age at the time of treatment or unawareness of pregnancy was probably the cause of women being treated with AL during their first trimester of pregnancy.
Pregnancy outcomes
Malaria treatment and pregnancy outcomes
Study groups
Pregnant women
Pregnant women
P value
Treatment response
Adequate clinical and parasitological
1068 (99.6%)
Late treatment failure
4 (0.4%)
Parasite recurrence < 56 days after first AL treatment treated with quinine
Parasite recurrence < 56 days after first AL treatment, treated again with AL
Obstetric outcome
Uncomplicated at term deliveries
992 (92,5%)
926 (94.7%)
Mean birth weight of babies born at term
3.20 (3.17, 3.24; n = 936)
3.22 (3.19, 3.25; n = 893)
Length (95% CI, cm)
49.0 (48.6, 49.3; n = 666)
49.2 (49.0, 49.5; n = 645)
Head circumference (95% CI, cm)
32.3 (32.1, 32.6; n = 644)
32.5 (32.3, 32.7; n = 632)
Obstetric complications
80 in 78 (7.3%) 78 patients
49 in 49 (5.0%) subjects
14 (1.3%)
4 (0.4%)
Still birth
31 (2.9%)
23 (2.4%)
Premature delivery total
8 (0.7%)
3 (0.3%)
At term delivery, neonatal death
5 (0.5%)
4 (0.4%)
Cesarean section
3 (0.3%)
Infant death
10 (1.0%)
Fetal distress at birth
2 (0.2%)
Neonatal infection
2 (0.2%)
Stillbirth & hydrocephalus
Twins, first with cerebral anoxia
Still birth and maternal death
At term delivery, maternal death
2 (0.2%)
1 (0.1%)
Infant outcomes
Study groups
Pregnant women treated with AL
for malaria (n = 1072)
Pregnant women without AL treatment (n = 978)
P value
Total congenital malformations
3 (0.3%)
3 (0.3%)
Congenital aglossia
1 (0.09%)
Spina bifida
1 (0.1%)
Thoracic asymmetry
1 (0.1%)
Congenital malformation of left foot
1 (0.09%)
Hydrocephalus (stillbirth baby)
Neurological disorder
1 (0.1%)
9 (0.8%) (one still birth twin)
3 (0.3%)
Fetal distress
3 (0.3%)
Univariate and multivariate analysis of obstetric outcome
Univariate analysis
Multivariate analysis
Total no. of patients
No. of patients With adverse events with obstetric complications (total = 127)
P- Value
Pregnant women & malaria & AL treatment
1.03, 2.15
0.95, 2.01
Healthy pregnant women
49 (5.0%)
First trimester
10 (7.3%)
0.59, 2.25
0.53, 2.05
2 &3rd trimester
1.42, 2.97
1.71, 4.12
Mothers age (covariate)
1.01, 1.09
Retrospective inclusion of women who had been treated with AL for malaria was also allowed. In order to cope with the possibility that abortions after treatment with AL were not reported and, therefore, not included in the study, analyses were also ran on the subset of patients and controls who were included prospectively.
The total number of congenital malformations (six) was considered too small to do multivariate analyses.
A summary of recorded infant outcomes is shown in Table 3. Congenital malformations occurred with a similar frequency in both. Congenital anomaly also had same frequency of one baby in each group. There was only one infant in the control group with neurological problems, and no reports of this in the AL-treated group. There were two babies born with infection at birth (conjunctivitis) in the control group and none in the treatment group. Three patients delivered their babies by caesarean section.
The results from this pharmacovigilance study in Rwanda showed a significantly increased frequency of obstetric adverse outcomes but no significant increase in congenital defects after AL treatment for malaria during the first second and third trimesters of pregnancy, compared with pregnant women who had no malaria and received no anti-malarial treatment. The significant over-expression of obstetric events was observed in the AL-treated group. The slightly higher rates of abortion, peri-natal mortality, stillbirth and premature delivery should probably be regarded as complications of acute malaria itself. However, the distinction between the effects of malaria and AL exposure could not be made in this study. Chronic malaria in pregnancy is associated with low birth weight, increased anaemia and adverse effects on foetal growth [2]. It is estimated that around 8–14% of low birth weight and 3–8% of infant mortality is related to pregnancy-associated malaria, which relates to a global annual estimate of 75,000–200,000 infant deaths attributable to malaria infection during pregnancy [16].
The information gathered from this study adds weight to the limited, but expanding, body of evidence on the use of AL in the second and third trimesters of pregnancy. The safety of Artemisinins in pregnant women has been the subject of a number of publications, and AL is the ACT with the most data on safety in pregnancy so far [2]. Several studies have reported that Artemether and AL do not have teratogenic effects [17–20]. A recent study in Zambia evaluated the safety of AL women with malaria in all trimesters of pregnancy [21], and exposure to AL was not linked to any particular safety risks with regards to perinatal mortality, birth defects, or developmental impairment. Patients receiving AL treatment during the first trimester of pregnancy had no greater risk of peri-natal or neonatal infant death or stillbirth [21].
Strengths and limitations of the study were both apparent. The sample size was large, and women were followed closely for any adverse event. In this study loss-to-follow-up was very low, besides the implementation of active follow-up by a study nurse this is partly because of the nature of the Rwandese health system which gives incentive to any pregnant women who completes all the antenatal visits during pregnancy like delivering for free at the health facility. In addition Rwanda has a nation-wide health insurance programme that covers over 95% of the population. The creation of a Rwandan anti-malarial exposure registry to follow the effects of implementation of ACT in pregnant women represents an important step forward in pharmacovigilance in this vulnerable population. Not all women had malaria confirmed via a positive blood smear and, therefore, it may be possible that women who were diagnosed based on clinical symptoms alone (presumed malaria) may have been suffering from another febrile condition. At the time of this study, malaria was classified and treated as either confirmed or presumed. This represented normal clinical practice in Rwanda, which has changed now; rapid diagnostic tests (RDTs) were only introduced in April 2008 [22]. Only patients with uncomplicated malaria in their second and third trimesters of pregnancy were enrolled in the study, as in national policy; however, subsequent analysis revealed that a small group of patients were actually in their first trimester during the study. This may be due to the fact that health care workers at the primary health centers may not be able to estimate the gestational age properly or even the women themselves do not report pregnancy accurately. This study does not include the follow-up of children for minor or undetectable neurological defects; follow-up of children will be reported in a different study.
Further evidence on the safety of pregnant women exposed to ACT during the first trimester of pregnancy is required. In general, there are ethical issues associated with the inclusion of women in randomized controlled trials in the first trimester of pregnancy. However, the WHO has suggested that there may be occasions where the need for effective treatment of the pregnant febrile patient may outweigh the potential for toxicity to the foetus [6]. For example, in cases of severe P. falciparum malaria, where maternal mortality is high and thus an investigation into the efficacy and safety of a new drug would be justified, or in instances of ineffective current treatments where a study comparing ACT and standard treatment for women with a recrudescent infection could provide important information on abortions and malformations if treatment was delivered and monitored during the first trimester, and second and third trimester exposure would provide critical information on the incidence of low birth weight and stillbirths [6].
Overall, peri-natal mortality and the incidence of congenital malformations was low in the AL-treated and control groups. There was however a significant increase in the overall obstetric adverse events in the treatment group. This may however be related to malaria or other febrile illness rather than AL treatment in pregnant women.
Although AL is used for treatment of malaria in the second and third trimesters, a number of women are also exposed in the first trimester, hence close monitoring of women in all stages of pregnancy is still needed to determine the safety of AL, especially with a long follow-up until children reach school age, to be able to detect minor neurological adverse events.
This study is part of the NACCAP-funded INTERACT programme.
We thank patients and staff of participating health centres and INTERACT staff in Kigali.
Authors' Affiliations
- Government of Rwanda (GOR): Rwanda National Health Sector Policy -2005. 2005, GOR, http://www.eac.int/health/index.php?option=com_docman&Itemid=47, Accessed 1 October 2011Google Scholar
- WHO: WHO Guidelines for the Treatment of Malaria. 2010, World Health Organization, Geneva, SecondGoogle Scholar
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- EMEA: Guideline on the exposure to medicinal products during pregnancy: need for post-authorisation data. 2005, EMEA, http://www.ema.europa.eu/docs/en_GB/document_library/Regulatory_and_procedural_guideline/2009/11/WC500011303.pdf, Accessed 3 June 2012Google Scholar
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- WHO Multicentre Growth Reference Study Group. WHO Motor Development Study: Windows of achievement for six gross motor development milestones. Acta Paediatrica Supplement. 2006, 450: 86-95.Google Scholar
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Frankfort Rt. 30 Commercial Corner
|Frankfort Township
|8346 W. Lincoln Highway Frankfort IL 60423
|Gross Land Area:
|3.5 Acres
|Hectare Conversion
|Property Type:
|Vacant Development Land
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Listing Details
General Information
|Listing Name:
|Frankfort Rt. 30 Commercial Corner
|Tax ID Number/APN:
|19-09-23-100-008-0000 (.56 Ac)
19-09-23-100-014-0000 (40.9 Ac) Part of this Tax ID#
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Area & Location
|School District:
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Summit Hill School District 161
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Land Related
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Approximately 241 feet of frontage on 84th Ave.
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Frankfort, IL 60423
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Mark Goodwin is a Illinois Land Broker who can advise you about your land asset. It takes an experienced Illinois Land Broker to understand how best to market your land asset or find the property that best fits the investors needs or desires. Goodwin and Associates is the Land Broker for you in Illinois. We can help you with the marketing of your farm, residential development land, industrial land and commercial land or help with the selection of farmland, commercial land, retail land, industrial land, residential development land, residential lots, industrial lots and commercial lots. We are here to help you reach your goals.
Mark Goodwin - Illinois Land Broker
1-815-741-22261-815-741-2226 email@example.com
Goodwin & Associates Real Estate, LLC
is an AGENT of the SELLERS.


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Fun and unique, Meri Meri's Cactus Necklace would bring a touch of the Wild West to little jewellery collections.


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Sara is a young nurse leader with loads of potential. A few years ago, she left direct patient care to take an advocacy role in her local area, and last year she took another advocacy position with a large association. She is eager to focus her considerable talents on healthcare policies that will make life better for patients and the institutions that serve them.
Sara is a hard worker, and she never shirks from fully preparing for the challenges before her. Sara also has a strong sense of right and wrong. While this usually serves her well, recently she began to feel frustrated with how things are versus how they "should be." She was especially irritated with several of the healthcare CEOs in her region. She said they didn't know the substance of key policy directives, and she also complained that they talked down to her because she is young and attractive.
It is reasonable that Sara was concerned that her colleagues didn't know key elements of their jobs, and it is also understandable that she was distressed by what she considered to be poor professional behavior from people who were many years her senior. She was justified in expecting better.
But Sara couldn't let go of her indignation. She insisted that she was right to be incensed, and she complained that she was hindered by their bad behavior. She was quite emotional when she talked about her colleagues' transgressions and their effects on her. Unfortunately, some of her other peers started to complain about Sara's own "bad behavior."They experienced her grievances as whining and immature, and they wanted her to "get over it and move on."
As a result, Sara's work relationships began to suffer, and she was having trouble focusing on important policy initiatives. She knew she was not at her best, but she couldn't see a way out of her predicament. She said she was stuck because she was right and the CEOs were wrong, and she didn't see that she could, or should, change herself when it was her older colleagues who should change.
Many of us can relate to Sara's dilemma because we, too, have been caught in the web of other people's imperfections and their effects on us. It can be quite difficult to see that other people's poor behavior can adversely affect how we behave, too. It's also hard to accept that other people don't always behave the way we think they should. We, too, may have asked what Sara was asking: how can I maintain my high standards and continue to work productively when those who should know better fall short of my expectations?
Eventually, Sara found ways to move on. She made progress by:
1. Remembering a truth that's obvious but easy to overlook: we cannot change anyone but ourselves. We can try to influence, cajole, lecture, complain in front of them or behind their backs, but, ultimately, no one will improve or change anything about themselves unless they want to. As we mature, we can try better tactics, such as being assertive and asking for what we need from others clearly and without being aggressive. But even then, we cannot guarantee that they can or will meet our needs. In the end, we must attend to ourselves.
2. For Sara, the next step was to notice where she was placing her attention. She understood that instead of focusing on her own work and her own behavior, she was concentrating on the actions and problems of others. She also realized that as compelling as it was to focus on them, it was also a luxury. Unless Sara was blessed with boundless energy and endless goodwill with her peers, she was choosing to tarnish her reputation and devote her most productive hours to addressing the shortcomings of the CEOs rather than doing her own work.
3. But what was her own work? Certainly, Sara knew her job description and what she was responsible for. But was she clear about her priorities? What were her most significant goals, and, equally important, how did she want to comport herself as she sought to achieve them? As she thought about her priorities, Sara did a mental evaluation of her progress. She considered whether she was advancing her projects as well as she had planned. She was also honest with herself about whether she was conducting herself like the leader she wanted to be.
Like many of us, Sara saw that there was room for improvement between what she wanted to achieve as a leader and what she was achieving as a leader. She saw that she was spending a lot of time thinking and talking about others' problems at the expense of her own effectiveness. That gap served as a wake-up call for Sara. She realized that she could refocus her attention and concentrate on closing that gap.
4. Lastly, Sara thought clearly and carefully about the effect the CEOs' behavior had on her. Was she really hindered by the way they treated her? Was she truly a victim of their poor habits and lack of professionalism? Although she was mighty exasperated, Sara concluded that, in fact, their conduct did not interfere with doing her job. So, eventually, Sara chose to reframe her view of their behavior as annoying irritations that she could live with and manage. She did not condone their actions, but she did affirm that she would always speak up for herself and ask for what she wanted. She also declared that she would no longer let her frustration about the CEOs distract her from doing her job and accomplishing her goals.
In the end, Sara saw that she had inadvertently abdicated her power as a leader and as a competent professional by concentrating on poorly behaving colleagues instead of concentrating on herself. She understood that her misplaced attention profoundly affected her productivity, work ethic, reputation, and career potential. Finally, Sara rededicated herself to focusing on her own work and to nurturing her potential to become the outstanding nurse leader she knows she can be.
* This article was originally published in Nurse Leader.


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Mai Chau
"Located in Hoa Binh province, about 150 kilometers west of Hanoi, Mai Chau district has about 50,000 inhabitants, including seven ethnic minority groups – the White Thai, Hmong, Zao, Muong, Tay, Hoa a Viet. The stunning mountainous scenery and tribal culture of Mai Châu attract many visitors every year. The Mai Châu area is well known for its stilt house, they are called Thai stilt houses and are made of bamboo and timber, elevated 10–12 feet off the ground they avoid water damage and shelter animals from the elements."
Your journey will start at 8am from the lobby of your hotel, from where you will be transported to Mai Chau valley in Hoa Binh province approximately a 3 ½ hour drive through the stunning views of mountains & valleys. En-route you will stop to visit the Muong hill tribe village at Giang Mo or Toan Son.
Arrival at your accommodation will be about midday when you can check in enjoy lunch and relax until 3pm, when you will set off for a guided cycling tour of the surrounding villages and countryside to learn about local living, house styles & daily farming activities.
Enjoy dinner at your resort followed by a special show of dances & songs performed by locals. It is a great chance for an open cultural exchange with locals. You can dance, sing & drink local pipe wine (called 'Can' in Vietnamese) with them. Overnight in Mai Chau。
Accommodation: Mai Chau Ecolodge
After breakfast, the morning is yours to either take a hike or another cycle ride to visit the surrounding countryside before we depart at Midday for the 2hour drive to Pu Luong Nature Reserve.
Pu Luong
"Pu Luong Nature Reserve has a total area of 17,662 ha and ¾ of the nature reserve is primarily tropical forest. At the same time, this is the living place of ethnic Muong and Thai people. The region is quite unknown among most tourists, but that does not make it less worth to visit, it may attract you due to its stunning rice terrace fields, beautiful nature or breath-taking mountain passes and traditional villages of ethnic minorities who still retain their unique cultural heritage and way of living."
On arrival at Pu Luong Retreat, you can check in and enjoy lunch before setting off for an exciting afternoon…
You will be transferred to a suspension bridge over the Cham River, where you begin your walk in search of the stunning water wheels. Get up close to each wheel and discover how water is moved from the river to handmade bamboo aqueducts via simple constructions of all sizes. Take your camera for a brilliant photo opportunity…Arriving at a local fisherman's house, you have a short rest to gear up for the rafting adventure.
Float along the calm river and enjoy the views, in between learning how to paddle and steer your handcrafted rafts.
Arrive at the scenic Tan Lap bridge for more photos, where you disembark to be transferred back to Pu Luong Retreat for dinner.
Accommodation: Pu Luong Retreat
After breakfast, you will start your trek by descending into the beautiful valley facing the Retreat where you will walk around tumbling rice terraces.
Trek through small paths shrouded in vegetation to slowly reveal a picturesque village sitting at the base of a towering mountain. Your camera will not be able to sit still! Continue to the base of the valley, you weave between roads and farmland, villages and wild fields, ponds and rivers, mountains and open land. Savour the ever-changing scenery as you trek to a beautiful spot to enjoy a simple picnic lunch. After enjoying delicious food, you have free time to explore the surrounding area or take a dip in the water at a nearby river, before moving to the pick-up point to be transferred back to the Retreat to enjoy the remainder of the day at leisure.
Accommodation: Pu Luong Retreat
After breakfast, it's an early start as you head off to Hoa Lu, approximately 3 hours from Pu Luong. Arrival at this ancient Capital will be at about 11am. In Hoa Lu, there are 2 temples which have been built on the grounds of the old Royal Palace, one is dedicated to King Dinh Tien Hoang, the other is to King Le Dai Hanh. This visit offers a chance to learn more about the feudal dynasties in Vietnamese history, as well as the old feudal architecture of Vietnam Temples.
Onward then to Tam Coc where you will enjoy lunch in a local restaurant, after which you will take a short walk to the boat station and start the 2hour- sampan boat trip with a local rower, to visit Tam Coc, known as "Halong Bay on land". You will visit the three limestone caves stretching along Ngo Dong river, Hang Ca (first cave), Hang Hai (second cave) and Hang Ba (third cave), passing peaceful scenery of limestone mountains, rice paddy fields and the site of some temples along the way. An optional cycle ride is available at your own cost on arrival back at the jetty. Your return to Hanoi will see you arrive at approximately 6pm.
Note: As an option, you may choose to overnight in Ninh Binh and head to Halong bay the following morning. please contact us for a quote.
Accommodation: As selected
We Hope To See You Again Soon


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Thank you for your interest in contacting Sustainable Jersey for Schools.
You can call us during our normal business hours Monday–Friday 8:30 a.m.– 4:30 p.m. at 609-771-3427, or email firstname.lastname@example.com.
If your inquiry pertains to the Sustainable Jersey Small Grants Program email email@example.com or call 609-771-3189.
If you are a member of the media and are looking for information or would like to contact our public relations staff, visit our Media and Publications page and/or call 609-771-2938 or 973-762-1510.
If you would like to send something to Sustainable Jersey via Mail, Fed Ex, UPS or other service, please use the following address.
Sustainable Jersey
at The Sustainability Institute at The College of New Jersey
Forcina Hall, 3rd Floor
P.O. Box 7718
Ewing, NJ 08628-0718
Fax number: 609-637-5162


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2014 Foley Sonoma OZ Zinfandel, Alexander Valley
Winemaker Notes
Originally planted in 1896, the Oz Vineyard is one of the oldest vineyards in Alexander Valley and we are pleased to be able to craft such a stunning wine from our friendly neighbors! At first sip of this 2014 Oz Zinfandel, the nose greets you with mocha, dark cherry and juicy plum. The wine coats your palate with its beautiful dark fruit and toffee notes followed by its smooth and gripping tannins. Drink now or hold until 2020.
Food Pairing Notes
For a decadent treat, pair this wine with a dark chocolate truffle.
90% Zinfandel, 10% Petit Verdot
Wine Specs
Alexander Valley
Harvest Date
September 8, 2014
5.8 g/L
26 months in French oak, 40% new
Alcohol %
Production Notes
The Osborn Vineyard, or "Oz" for short, is our northwest neighbor. While very similar to the soil of our Estate Old Vine block, Oz differs in that it produces fruit that creates a more earthy profile and boldness on the palate. After harvest, the grapes were fermented in stainless steel tanks and then racked to French oak barrels. After aging for 26 months in barrel (40% new) with regular lees stirring, the wine was bottled.
Vineyard Notes
2014 was another early and warm vintage. This resulted in prime flavor development of the fruit to display its finest attributes. Overall, the vintage produced grapes of high quality, dense flavors, and balanced acidity. The grapes were harvested on September 8, 2014 at optimum ripeness.
Only 369 cases produced


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Complex Pattern from Simple Arcs – Example 3.6
Just to demonstrate one more time how complex patterns can be developed from very simple initial forms, we are going to do what we did in example 3.5 and do a Pick n' Choose, this time with just one arc rotated in 1 of 4 directions.
The results look quite good, in my opinion, even though its a very simple premise. Certain forms start to emerge from this random distribution.
Slight variations can produce quite different patterns. One produces cats….
And even a simple diagonal line from top left in two different options can create a maze…
So these are just a few possible variations. The lesson is that simple elements randomly combined can become quite complex.
Here is an image with 3 possible variations of the "arcs" script just changing the random number seed, and then some of the other variations…
And here is a screenshot for a script that would produce the first 3 variations. Minor variations to the script would be needed to produce the other variations.


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Lululemon Athletica Inc (NASDAQ: LULU)
Growing up in Vancouver, I had the pleasure of witnessing the rise of the Lululemon empire first hand. Back in the mid- 2000s,Lululemon apparel really started hitting its stride: fashion conscious young women began noticeably, and in large numbers, sporting the iconic black yoga pants with the white omega symbol all across Vancouver. As the yoga pants gave way to criticisms, complaints, and memes in the wider public, more and more Lululemon apparel started appearing on the streets. Popularity surged and a little known company from Vancouver, Canada that was once known merely for its black yoga pants is now a $8.5 billion market cap, publicly traded company.
It's not hard to see that the brand is immensely popular. It dug out a niche in the "athleisure" apparel through fashionable yoga inspired clothing and was a first mover, allowing it to quickly grow market share and command premium margins on its products. It has expanded its product line to include more than just yoga pants: Lululemon sells athletic-leisure shirts, jackets, coats, sports bras, underwear, and other athletic apparel.
Over the past ten years, has grown revenue from $84 million to $1.8 billion. Net income has grown from $1 million to $239 million. Net margin has increased from 1.7% to 13.3%. Free cash flow has grown from essentially zero to $195 million. Operating cash flow has consistently eclipsed net income over the past ten years, which hints at a strong ability to generate cash from the business.
On top of this growth, Lululemon carries very little debt. Current assets, of which 70% is made up of cash and short term investments, outstrip current liabilities by almost 6 times. There is absolutely no long term debt on the balance sheet. It carries a current ratio – total assets divided by total liabilities – 6.3. The balance sheet is very pristine and a thing of beauty to look at.
Based on profitability ratios, Lululemon is generating Return on Assets of around 20%, Return on Invested Capital of around 20%, and Return on Equity of around 22%, all while employing very little financial leverage, as the note on the balance sheet in the previous paragraph indicated.
Looking through these numbers, and first hand experience with the product, it is not hard to see that this is a strong brand with quality cash generating capabilities. Yet, although the enterprise is most definitely attractive, we must analyze if ownership in the enterprise at current prices is attractive. A single stock of Lululemon is currently trading at around $60 per share. With 2015 earnings per share at $1.83, you have to pay 33 times current earnings to buy into the enterprise.
Analysts project growth for Lululemon to be around 15% over the next 5 years. Doing a quick, back-of-the-envelope calculation based on current prices and projected growth of 15%, we can see project that earnings per share could be at $3.68 per share by 2021. Now, if the market is willing to pay the same 33 P/E multiple in 2021, buying at current prices would compound at 15% over the next five years. If the stock experiences some mild P/E contraction and the market is only willing to pay 30 times earnings, you get to compound at 13%. And if the market is only willing to pay a 25 times multiple, you will have compounded at 9%.
Lululemon operates in a fiercely competitive market. The athletic and athletic-leisure apparel sector is strife with competition, with big players like Nike (NYSE: NKE), Under Armour (NYSE: UA), and The Gap (NYSE: GPS). The competition is fuelled by the attractive margins and growing popularity in the "athleisure" style. I think it would be too optimistic to imagine that Lululemon will continue to enjoy a 30+ earnings multiple as competition intensifies for consumer dollars in the sector.
In order to build in a margin of safety, I believe it would be wise to assume a P/E compression into the mid-to-high twenties out in 2021. This would mean that at current stock prices, you could expect the stock to compound at an annual average rate of around 9% to 10%. While these are potentially solid figures and nothing to sneeze at, one could expect similar results with much less risk with a holding in Colgate-Palmolive – all things equal, Colgate is the more logical choice in this scenario as it provides a better risk-adjusted return.
Therefore, while Lululemon is an attractive enterprise, with a pristine balance sheet and a sound economic engine that pumps out torrents of cash for its owners, I wouldn't initiate a position now, but would rather wait for a more attractive entry point when a dip in the stock price occurs. I don't believe the current asking price for an ownership stake will provide a superior return to other, better risk-adjusted options.
Disclosure: This author has no positions in any stocks mentioned and does not plan to open any positions in any stocks mentioned for at least 72 hours after publication of this article.


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Every Time We Say Goodbye
Those are the opening words of Cole Porter's 1944 classic and, I believe, a pretty good way to begin this, my last Connection article. I say that because this is not the first time we've said "goodbye," and maybe not the last. Who knows what the future holds for any of us?
Many years ago, Pastor Wil Bloy planted a seed in me which took root and Read more >>
Some Gleanings
from Adam Hamilton
There were not many highlights from Annual Conference this year but one of them was the presence of Rev. Adam Hamilton as our Bible study leader. Hamilton is no stranger to us as we have used many of his books and videos in our adult study groups. He is the founding and lead pastor at Church of the Resurrection in Kansas City, Missouri. Today this church is the largest in our denomination.
We were blessed to have Hamilton with us for three ninety-minute sessions at Conference and he comes across in person just as he does on his videos, someone who is quite Read more >>
Great Expectations – Take Two
Being a history-minded person, I like to look back from time to time. With that in mind, I looked back at my Connection article from May of last year. That article was titled "Great Expectations" and in it I spoke in part about the expectations that most of the sports world had placed on my beloved Chicago Cubs. I even wondered if this "could finally be "the year?"'
Well it certainly was as my Cubs won their first Read more >>
Who We Are Together
Last month Pastor Kelly wrote about our need to "belong" to something. She highlighted the fact that our desire to belong is a biological one…satisfying a basic human need to feel connected and safe. I couldn't agree more! Consider for a moment what groups Read more >>


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Police looking for 15 people in relation to crimes
POLICE are asking the public if they recognise 15 people from CCTV footage in the Goodna, Redbank Plains, Springfield and Collingwood Park areas.
The most recent is a man they believe might be able to help with an investigation into a recent wilful damage which occurred at Redbank Plains on Saturday October 6, about 1am.
Another is a woman in Collingwood Park who they believe might be able to help with investigations into a recent shop steal on Saturday September 22 about 4pm.
- Police are also looking for a man in relation to a shop steal at Smiths Rd, Goodna on Saturday September 29 about 4.45pm.
- Police are trying to track down a man in relation to a petrol drive off a Bellbird Park on September 28 about 11.39pm.
- A woman is being sought to assist officers with the investigation into a shop steal on Monday August 20 about 11:35am at Main St, Springfield Central.
- Two men are sought in relation to an armed so as to cause fear or alarm on at Brisbane Tce Goodna on Tuesday September 11 about 10:30am.
- Police are looking for a person to help with an investigation into a shop steal on Monday September 10 about 2pm in Collingwood Drv Redbank.
- A person who rode a motorbike on Lakeside Ave at Springfield Lakes is sough in relation to traffic complaints on Thursday September 20 about 10:30am.
- They are also looking for seven people who rode motorbikes on Goodna Bikeway at Redbank Plains between September 16 and 24 at various times of the day.
Police warn not to approach these people, but to report information to police by calling Policelink on 131 444 or Crime Stoppers on 1800 333 000.


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When I was in the CVS the other day to buy dish soap, I experimentally picked up some "magic eraser" sponges, as they said they were good for cleaning stove tops, and I was thinking that needed doing. HOLY COW THEY ARE MAGIC. They don't smell like any sort of cleaner - just a fine-textured white sponge that you get wet - but they wiped up stove grime with no scrubbing or effort or anything. I randomly cleaned off the side of the fridge that has been accumulating little spatters for forever. I wrote on the wall with a Sharpie (just to see) and wiped it off - okay, that took more than one pass, but it still didn't require *scrubbing*. What the heck is *in* these things? I suspect nanites. (Wikipedia tells me it is "melamine foam".)
I'm kind of embarassed to be so agog over a cleaning supply, having been raised to think that there is no such thing as a soap or detergent or cleanser or cleaner or powder or paste or wax or bleach, that will make cleaning fun.... but, you know, at least this time, especially when I was testing the Sharpie I had written on the wall with... it was fun.


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Memory Search
The Memory Search (or Translate) tool finds all information from your Lilt Memory for a given source string. It shows MT output, and all TM matches (incl. meta information). It automatically updates according to the current segment that is focused in the Editor, but you can freely enter any text you'd like to search for.
Highlight source terms and click on the translate icon to access the Memory Search:
When you click the translate icon, the Memory Search will expand from the right side of the window:
Results indicate from which resource type they are coming from: MT (machine translation), TM (translation memory), or TB (termbase). First, the MT is shown. Then TM matches are ordered according to their match percentage. Finally, terms from your TB are listed.


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The Opportunity North East (ONE) team is based in Aberdeen and led by the chief executive. Our team works with the ONE economic leadership board and the sector boards on the identification and delivery of projects.
Jennifer Craw
Chief executive
Maggie McGinlay
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Lindsay McKenzie
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Nat Anderson
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Leona Minellas
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Nicola Fraser
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Jane MacLeod
Business growth manager, ONE Food, Drink & Agriculture
Lorna Duguid
Project manager, ONE Life Sciences
Jackie Doyle
Director, Digital & Entrepreneurship


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All paint needs a clean surface for a good bond. Hot water and steam are used to remove that final film of grease.
Retail businesses need to make a good first impression which requires a clean and well maintained store front; this is accomplished with regular cleaning of the front of the business, and the sidewalk and parking lot as well.


text: AWERNER PARTNERS has been set up unknown in state . The current status of the business is . The AWERNER PARTNERS principal address is 000000000363436331IL300 E. ROOSEVELT ROAD, WHEA, TO, N. Meanwhile you can send your letters to IL60187. The company`s registered agent is 000002200 BREVARD ROAD N.E., ST. The company`s management are Treasurer, E, R, Secretary - Urg Fl33704 000000000000, - 0213200. The company annual reports filed on Annual reports – unknown.