text:
Cary100 Restaurant & Lounge
100 E. Cary St. (1st St.) Send to Phone
804-643-9736 | Make Restaurant Reservations
OpenBreakfast, Lunch & Dinner Mon.-Sat.
- Dress code: Casual
- Entertainment: Ask for schedules
- Full bar
- Kid-friendly
* Click here for rating key
Cary100 Restaurant & Lounge Restaurant Review: Known as Becky's for more than half a century, a rebrand has given this restaurant a more contemporary, urban décor. But at its heart, it's still an American eatery, with loads of all the good Southern fare that's true comfort food, like chicken and waffles and mac 'n' cheese, and the same friendly staff, too. Omelets and home fries endear themselves to loyalists at breakfast, and sandwiches such as a catfish po' boy roll out at lunch. Really hungry at midday? You can order up all the works with such entrée platters as braised pork chops and two vegetables. Don't forget to ask about daily specials; Wednesday means liver over rice. Roasted bone-in chicken simmered in gravy is just one of the reasonably priced dinner picks and dessert might be lemon pound cake or a hot fudge sundae. Eat up to gird yourself for partying come nightfall.


text:
9 comments:
Love the striped trench!! Perfect for a rainy day or even a light Spring day. ;)ReplyDelete
xo - Sheila
Thanks Sheila, I agree it's perfect for rainy or slightly chilly weather. Not so much real cold!Delete
Oh hey, there are the leggings I bought because of you. :) Love how you paired them with a trench and flats. And yeah, the rain is pretty cozy when it's a rare treat like it is here in SoCal. When you have too much of it it's another thing entirely, but it was fun to stay indoors and cozy this weekend. Glad you and Mr. Noelle enjoyed it! -GinaReplyDelete
On the Daily ExpressReplies
You always leave the sweetest comments Gina :) I wear these leggings mainly with my coats because the thought of showing my bum scares me! Even a longer blazer or shirt isn't enough coverage for me, so I don't wear these as much as I should! And yes, little doses of rain is great! We enjoyed it :)Delete
Yay it's the striped trench! Can't wait till it is a bit warmer to pull mine out!ReplyDelete
I agree...rain = snuggle day :)ReplyDelete
I absolutely love rain on a day when you don't *have* to leave the house!ReplyDelete
What a great trench! I'm loving it so much! How cute would it be with a red umbrella!!
carylee @ morepiecesofme.com
aahhh i adore this outfit hon! you look like you're jetting off to paris for the weekend! you look so fabulous!ReplyDelete
Love your outfit! That loft trench is so pretty. Love the color and print. I find this outfit classic and trendy. Great choice!ReplyDelete
Thank you for commenting! I read each and every one, and do my best to answer questions or return the favor on your blog.

subset: commoncrawl


text:
Hey Beauties!
I was dying to use the Colourpop Sol Eyeshadow Palette and came up with this sunset vibe which I ended up loving! This palette is also everything in terms of pigmentation and blend-ability.
Hope you have a stunning week!
Foundation – Urban Decay All Nighter Foundation
Concealer – Makeup Revolution Conceal and Define
Powder – Colourpop No Filter Loose Setting Powder (banana)
Contour/ Bronzer – KKW Contour and Highlight Kit (Medium)
Blush – Tarte Cosmetics Blissful
Highlight – Makeup Revolution Ultra Pro Glow Palette
Brows – Mac Cosmetics Fluidline Brow Gelcreme
Mascara – Hourglass Caution Extreme Lash
Eyeliner – Essence Extreme Lasting (Silky Nude)
False Eyelashes – Kiss Dramatic Lashes (not really a fan of this style)
Lip liner – L.A. Girl Perfect Precision (bare)
Lipstick – Colourpop Lux Lipstick (Quickie) and Mac Cosmetics Matte Lipstick (Chili)
Lip gloss – Colourpop Lip gloss (Just Surfed)
Have you tried the Sol palette? What are your thoughts?
Thanks for stopping by 😊


text:
Hi everyone, I am Mustafa from Turkey.
I have 2016 model year of Seat Leon 1.2 TSI.
I wanna ask some fault codes about my car. I hope you can help me.
I scanned my car by VCDS cable. A fault code was dedected. I cleared that. A week after i scanned again. Same code was there and i cleared. A week after i scanned again, same fault code was there.
At fault code's date, i didnt remember anything. Engine light or some light else are not on.Code:
Removed. Data from a clone/pirate copy of VCDS is not welcome here.
I asked a mechanic. He said reason is battery,probably battery voltage is low.
I checked battery voltage on car' electronics. It was 11,4 V.
Now there is no problem about car's driving or something else. But fault code is still there.
What will i do? What are you guys advise to me?
Thanks in advance.


text:
Chunky Signet in Opal and Turquoise
Chunky signet ring inspired by antique styles, with a wide muted knife-edge band and sleek hexagonal face featuring asymmetrical stones.
- Marquise Turquoise and Round Opal
- Gold Plated Bronze
Please keep in mind that all of our stones are natural and therefore vary in color from each other. We pick the prettiest colors available, but please understand that we may not be able to offer the exact stone colors that are photographed.
All jewelry is handmade to order, please allow 1-4 weeks for delivery.


text:
Again, I count myself lucky to have a good placement. They have never provided counselling as a service before, but they have been nothing but supportive.
We created a set of operational guidelines together, to make sure that their confidentiality clauses etc, matched mine, and they asked for some basic demographic information but the assessment itself they left entirely to me, which as a person-centred trainee, had been concerning me- I wanted an assessment process that 'gelled' with me, rather than having one imposed upon me.
I wrote a few versions of my assessment form- age, location, health issues, drugs? 'Why come for therapy?' But they all felt too clinical. In the end I took the demographic and contact details that I needed and then asked 'are there any health conditions I might need to know about for health and safety?' (Ie, epilepsy, etc), 'what brings you here?' And 'do you have people in your life you can talk to?'
That last question written in conjunction with Fred- we wanted to be sure that I, with zero 'real' hours, and no assessment experience, would be able to accurately make an assessment, and it seems to me that I can take 'deeper' issues if the person has a good support network. It would concern me more if the client wanted to talk about distressing life events and had no-one in their lives, so a 'safety mechanism', if you like. Originally, Fred and I discussed seeing a client and then letting them know at a later date if I would take them, but ultimately agreed that it was better if I trusted my gut on this, rather than think it all over: I had a sneaking suspicion that my mind wouldn't actually change for having a few days, but I did feel it might be distressing for a potential client to have to wait.
And I was ready to assess client one!


text:
Patterson Dental Software
Categories: Cements and Desensitizers : Cement Orthodontic
GC Fuji ORTHO™ BAND LC Automix, Paste Pak Starter Set - GC America Inc
GC Fuji ORTHO™ Band LC is a dual-cured resin-reinforced glass ionomer cement that is especially developed for the bonding of bands and appliances. It releases fluoride long term, which aids in the prevention of white spot lesions.
- Adequate retention and less damage after debanding
- No influence with saliva
- Unique gel conditioner increases bond strength without damaging the enamel
- Moisture-tolerant adhesion for easier bonding
- New automix paste pak system simplifies application, ensuring a perfect mix
- Stress-free placement
- Comparable retention strength to resin


text:
Red Gracillaria is a favorite food for many grazers. Attach it with a lettuce clip to the aquarium wall and watch as your fish engage in a feeding frenzy. This algae may also be used as decor in aquariums without herbivorous fish or inverts.
Red Gracilaria
Product added! Browse Wishlist
The product is already in the wishlist! Browse Wishlist


text:
LS1 Integrated Safety & Security Plan 2015
The Lyttelton Sector 1 Community Policing Forum (LS1 CPF) structure was established 4 years ago under the Police Act. This structure makes provision for the involvement of the community on a voluntary basis to assist SAPS in crime detection and prevention. The crime has however escalated and innovated over the past few years that the current structure is insufficient and more innovative measures must be implemented to support the current efforts.
LS1 CPF has therefore embarked on the implementation of an ISSP for the Zwartkop Residential areas in partnership with ADT Security, and the first phase of implementation will be a dedicated patrol vehicle project that entails the following:
A dedicated vehicle will be introduced to patrol and respond in Zwartkop as well as a network of License Plate Recognition Cameras will also be implemented. The LPR system captures all license plates of vehicles passing the camera and information is sent through to our Community Control Centre and checked against various databases, including a national SAPS database of stolen, suspect or wanted vehicles.
In addition to this, CCTV cameras will be deployed at strategic points. Equipped with Ultra-Smart Analytics technology, the video analysis makes use of artificial intelligence algorithms to learn the normal behavioural patterns of objects captured on a CCTV camera. When an object displays activity that does not fit the model of normal behaviour, the system highlights it as unusual and performs a number of automated responses. The system transforms a security environment from passive to proactive.
As with any project the community participation is essential and LS1 CPF in partnership with ADT needs to create a database of all residents in order to start with the marketing of the project.


text:
Recent Posts
Tag Archives: alabama
Keeping it Real
I was going to share my fitness journey over the past year but since I've been in a two week slump and just now fighting my way out of it, I'll wait until next week when I'm back on solid … Continue reading
Posted in Resolutions Tagged alabama, broken resolutions, keeping it real, resolutions 1 Comment
Chore Chart and Weekday Morning Schedule
So one of my resolutions this year included getting more organized…pretty much in every area. I know I strive under structure and I'm about 100% positive Little Man is going to be the same way. Because just swinging it isn't flying … Continue reading
Tackling those Fitness Resolutions
Each year, thousands upon thousands make New Year's resolutions to lose weight and get healthy. Sadly, thousands fail. I'm pretty sure we all know at least 5 people who made those resolutions and weeks or months later, they've given up. … Continue reading
2015 Resolutions Part 1
This post might be a little long-winded. I can't sleep (not off to a great start to go to bed earlier). I'll keep it simple though. Back in January, I pretty much made the same resolutions that I have made … Continue reading
WOW It's Been Awhile!
I was taking a walk down memory lane and opened up the blog to read some past posts. I was shocked to see that the last post was in 2011!! WOW!!!! 2011??? Has it been that long? It really does … Continue reading
Posted in Random Tagged alabama, blogging 2015, broken resolutions, never give up, resolutions, starting over, the struggle is real 2 Comments
Field of Family
The reason I've slacked on my posts the past month??? Because over the past month and past several weeks, I've been taking photos for several friends to increase my ever so limited photography skills and experience. I've enjoyed every minute … Continue reading


text:
Cast: Suriya, Keerthi Suresh, RJ Balaji, Ramya Krishnan
Director: Vignesh Shivan
Music director: Anirudh Ravichander
Genre: Thriller/Action
Language: Tamil
Release Date: 11 January 2018 (USA)
Duration: 2h 20m
Vignesh Shivan (styled as Vignesh ShivN) has come out with a racy heist comedy entertainer Thaanaa Serndha Koottam (TSK), based on Neeraj Pandey's Special 26 (2013). Sivan has taken the basic plot and reworked it, made some crucial changes and given it a typical Tamil mass hero movie packaging (with generous helpings of Anirudh Ravichander's chartbusters) to suit local tastes.
It is an intelligently scripted film about a group of con men and women, with some outstanding performances by the lead actors — mainly Suriya and Ramya Krishnan. The film, set in the late 1980s, is about a group of people getting together and posing as a CBI raid team to commit heists. They are led by a daring and street-smart young man (Suriya) who due to circumstances and a desire to avenge the ill treatment meted out by a corrupt CBI officer Uthaman (Suresh Menon) to his father (Thambi Ramaiah), wants to hit back at the system. He is assisted by a team of con artists (played by Ramya Krishnan, Keerthy Suresh, Senthil, Sathyan and a few others) who have their own back stories.
They make it a point to raid corrupt politicians, bureaucrats and businessmen with a lot of black money. The corrupt people that they raid do not want any proof of their wrongdoings, so no FIRs are filed, and nobody complains to the police. As a corrupt minister says: "We can always make more money, but nothing should happen to our clean image". In short, Suriya and his team escape after every heist with their conscience clean and loads of black money. However, the real CBI catches wind of their activities, and a team led by Uthaman and an honest and ruthless investigating officer (Karthik) get on their tails, leading to some twists and turns in the plot.
The film belongs to Suriya in the central role, as a young man with a conscience and a desire to clean up the system, who isn't above using devious methods to con the rich and corrupt. He is fantastic and it is refreshing to see him in the strait-laced comedy scenes. With an ingeniously layered role and a brilliant act, Ramya Krishnan truly "steals" the show. Keerthy Suresh as Suriya's romantic interest shines as the coy con woman. Suresh Menon as the dirty CBI officer is aptly cast, while Karthik makes most of his role and is always in command. Comedians Senthil and Sathyan bring in the laughs. The soundtrack and background score by Anirudh matches the pace of the plot, and includes several hummable songs. Veteran Sreekar Prasad's editing keeps the film racy at 132 minutes.
But Thaanaa Serndha Koottam is not without its problems. The director has changed the climax totally from the original and made it message-oriented (like all recent Tamil mass hero films), making it drag a bit in the second half. He takes a dig at the corruption in the state's public service boards and the buying of seats in educational institutes, to justify the hero's stance
On the whole TSK is a fun film from Vignesh ShivN, and his smart writing comes across. In fact, at a fake CBI officer's recruitment scene a girl being interviewed by the conmen says she wants to join the agency to stop corruption in the society. When Suriya — impressed by the girl's motive — asks her name, she replies, "Sasikala" (currently in jail on corruption charges)! And most of the people who turn up for the interview, when asked for the full form of CBI, respond with: Central Bank of India!
TSK is an enjoyable ride for the entire family, and it's refreshing to see Suriya back in form.


text:
A Thoroughly Biased Guide to the Plugins You Need to Get WordPress Multisite Up and Running
Multisite is a fantastic feature of WordPress that allows you to easily create a network of websites and crown yourself "Super Admin."
But once you've activated Multisite for your WordPress install and set it up, what next?
In this post we'll look at the best plugins – all created by WPMU DEV – to help you manage your network. Each of the plugins below will extend the functionality of a basic Multisite install, adding features such as domain mapping, cloning, SEO, and analytics.
Pro Sites
Pro Sites lets you create your own profitable blog or site hosting network, just like our sister site Edublogs.org or WordPress.com. A great example of Pro Sites in the wild is Webinly.
With Pro Sites, you can offer and charge your users for access to features like premium themes, plugins, extra storage, domain mapping, better support and advertising removal.
Other features include rich statistics to help you make informed decisions about your network, front-end checkout, membership levels, and BuddyPress integration.
Infinite SEO
Infinite SEO is a powerful search engine optimization plugin built to support Multisite.
It features comprehensive sitemaps, title and meta data optimization, and automatic sitewide linking.
The neat thing about this plugin is that it allows an incredible amount of control on both a post/page and global level, so you can control what the world sees.
Anti-Splog is an absolute must-use plugin for Multisite users.
You'll need a WPMU DEV API key in order to use the Anti-Splog service, which allows you to limit the number of signups per IP address per 24 hours, human tests (reCaptcha, random questions etc), pattern matching so you can check site domains, titles or usernames against a defined set of regular expressions.
There's also a free version of this plugin if you want to take it for a spin before buying the premium version.
Domain Mapping and Multi-Domains
Domain Mapping and Multi-Domains are both fantastic plugins for managing your network domains.
Let's start with Domain Mapping. This plugin provides an simple way to point multiple domains to your primary hosting account. If you're a Multisite admin, this means you can map any domain to your network, giving you the option to offer domains to your users. Mapping domains can be fiddly, but Domain Mapping makes the whole process a straightforward affair. I even wrote a post recently on how to set it all up.
Multi-Domains, on the other hand, allows you to run an unlimited number of different domains from on Multisite installation. This allows you to easily create blogs at alternative domains to your main site, or give your users the options to choose the domain they prefer.
You can even combine Domain Mapping and Multi-Domains for even more control over your URLs. The plugin combo will let you map individual blogs set up to different domains to their own dedicated URLs.
New Blog Templates, Cloner and Multisite Content Copier
New Blog Templates, Cloner and Multisite Content Copier are just three of the plugins that make up our Multisite Copying Toolkit, a suite of tools that cover the bases when it comes to copying data from one site to another, and even multiple destinations.
New Blog Templates helps you ensure that every new site is created using a pre-defined set of content, themes, plugins and settings by specifying an existing site to be used as a template. Multiple templates can be created and categorized to build a library of templates to be selected by site admins and network members when creating a new site. As the templates are based on existing sites, the site can be updated and any subsequent new sites will incorporate those changes.
Cloner, the latest tool in the suite, lets you choose your own combination of nine site components, or all of them for complete site replication, and get a clone of any site on the network (except the root site). Clone a site for troubleshooting or staging, give users from one site access to another or simply copy content (including attachments) from one site to another in just a few clicks.
If you want to copy posts, pages, custom post types, users and even plugins to a single site, all sites or a group of sites on your Multisite network, then Multisite Content Copier is what you need. When copying posts and pages, this plugin ensures that all images are also copied across, making it a perfect tool for syndicating content from one site to any number of others. It also integrates with New Blog Templates, allowing Super Admins to also update the templates used for the creation of new sites.
Snapshot is Time Machine for your website.
This backup plugin lets you schedule a backup of a single install, a single site on a Multisite network or your entire Multisite network at an interval of your choosing from immediately to once-a-month.
You can create multiple backup jobs and the data can be stored locally or preferably on a host of external service providers including DropBox, Amazon S3 and Google Drive.
Ultimate Branding
Ultimate Branding lets you white-label the entire WordPress admin area, from the admin bar to the dashboard.
Removing all traces of WordPress from your site or Multisite network has many advantages. Having WordPress branding sitting alongside your own can cause unnecessary confusion for your users. The login page is just one example where WordPress pushes your branding to one side.
With Ultimate Branding, you can replace the login logo with your own company logo, update your favicon, help content and dashboard widgets, even replace the footer text.
Google Analytics +
Our Google analytics plugins lets you track and view your statistics for an individual post, a site or an entire Multisite network right from your WordPress dashboard.
The plugin displays beautiful charts and graphs in your dashboard and in the Post Editor.
This plugin is also compatible with Pro Sites, which means you can offer Google Analytics as a premium feature on your Multisite network.
Reader is a recent addition to our stable of plugins. This plugin turns your Multisite network into a community by adding Tumblr, WordPress.com and Edublogs-style "follow" features to your sites.
Modelled on Google Reader, you'll find many great features similar to Feedly and the WordPress.com reading experience.
But more importantly, Reader encourages your users to engage with sites across your network, without having to leave their site.
Even More Multisite Plugins
I've highlighted just a handful of the best plugins you need to get Multisite up and running. There are plenty more that I've left out because we have so many fantastic plugins for Multisite! But there are a few more that deserve honorable mentions.
Recent Network Posts
Allows you to display a list of recent posts from across your Multisite network on your main site.
Blog & User Creator
Allows you and your users to batch create gazillions of blogs and/or users, while setting passwords, urls, titles and more.
Recent Network Posts
Lets you display a list of recent posts from across your Multisite network on your main site.
User Reports
Create reports of all user activity across an entire Multisite network.
Add Existing Users
Allows you to bulk-add existing users to a Multisite network and even set roles.
Batch Create
Create multiple sites and users automatically by uploading a CSV or XLS file.
What Multisite plugin can't you live without? Let us know in the comments below.
WIN a Share of $5K
This #HostingMonth!
Subscribe to our blog this #hostingmonth for a chance to win one of 5 prizes of $1,000 WPMU Dev credit! Learn More.


text:
Research-and careers therein-rarely follows a linear path. Instead, it is often a long and winding road. These are stories about science and my personal experiences on this road.
My posts are presented as opinion and commentary and do not represent the views of LabSpaces Productions, LLC, my employer, or my educational institution.
Please wait while my tweets load
Banner photo adapted from image by Alexander Baxevanis under Creative Commons license.
Avatar created at SP Studio.
How AAAS and Science magazine really feel about sexual harassment cases in science
Video 1. belle chases her tail whilst precariously balanced. It's all well and good and fun... until she falls on her face.
OK. I am being a bit dramatic--amusingly dramatic, but dramatic nonetheless. The point is, regardless of profession or career stage, finding balance is a tricky thing--especially if you're the sort of person who goes "all in", and science really seems to select such persuasions.
Around the time I started visiting graduate programs, a seminar speaker lunching with students asked what our plans were after undergrad. When it came around to me, the conversation went something like this:
belle: I'm going after a Ph.D.
prof (glancing at my hand): You married?
belle: After graduation.
prof (cynically): Good luck with that. I went into grad school married. I came out not married.
After that conversation, one criterion for graduate programs was 'still married when I finish'. (That was later expanded to 'still married and not in jail for strangling Ph.D. adviser', but that's a story for another time.) Here we are, 7 years later, and I'm still married. Of course, that's not to say it's been easy, as both Paramed (aka my husband) and I are extremely driven, passionate, and stubborn individuals.
Paramed and I grew up in the rural Southeast, where it's not assumed that every--or even most--high school graduates will continue to college. To this point, our decisions about where to go and what to do have been largely driven by my career, and Paramed has been incredibly supportive of every step. He took on a great deal of the domestic responsibilities while I was in grad school. On more than one occasion, he brought me dinner when I was working late. The week before my defense, he got on a plane by himself (and he really, really hates flying), came to postdoc city, and found us an apartment. In short, Paramed is awesome.
A year ago, Paramed took a big step toward his career goals when he finally got the opportunity to start working on his Bachelor's degree full-time. Our financial position--living in a city with a high cost of living plus debt derived in part from education and associated costs and in part from being young and stupid--is far from ideal, and he has had to continue working. His first semester involved a full class load distributed over 3 days plus two 24-hour work shifts every week. The next semester he was able to drop one of the shifts. What this means is that Paramed and I stay busy Monday through Friday with school and work, respectively. Before 6:30 Saturday morning, Paramed leaves for work, providing emergency medical care in one of the less savory parts of the city. When he drags in around 8 am Sunday morning, he considers himself lucky to have gotten more than an hour or two of sleep. Hence the first half of Sundays typically involve Paramed catching a long nap and me going grocery shopping. Somewhere in the midst of all this madness, we have to find time to (try to) clean our apartment, do laundry, pay bills, etc.
To make it work, we have to enjoy the little time we have. Sometimes it's as simple as working together fixing dinner in our tiny kitchen or kicking back on the couch with a movie or hanging out in a park reading a book or walking home together from work. Occasionally it's splurging on a nice, long relaxing dinner, free from the distractions of TV, email, phones, and so on. I have learned that, despite my protestations to the contrary, often the science can wait one more day. So I take those official holidays--things like President's Day and Memorial Day--so that Paramed and I can have an entire day off together, and I'm getting better about not feeling guilty about not being in the lab.
Even though we've conditioned ourselves to try to make the most of the time we have, we are not always successful. Often the limited time we spend together is actually spent slogging through some pretty serious issues, which can involve some very heated debates. We have learned, though, that these arguments get at the heart of issues needing to be addressed, and we have learned to forgive each other and use them as jumping-off point for moving forward. Paramed and I know that it doesn't necessarily get easier with time. In fact, decisions have been made that will almost certainly add more strain and stress. However, we know that for us to be happy together we also have to be happy with ourselves. So we move forward together, trying to balance two careers and our relationship together. We've made it 7 years. With a little luck, maybe we'll make it 70 more.
This post has been viewed: 455 time(s)


text:
⇐ Back to the Discussion Board Main Page
Posted by Jeremy Crouch on 07/13/2016
Hi Carmen, I have to disagree with you on your "centrifugal force is not similar to gravitational force" comment. And I hope I have understood your comment correctly... But you would indeed fall back 'down' to the wall if you jumped up. Unless of course you jumped up with enough force to cancel out your 'downward' momentum. If you were standing on the wall, your body is traveling along with the rotation of the Stone. Your body tries to fly off down through the wall, but cannot. Hence you feel a downward force similar to gravity. If you jump up, your body still has the forward momentum from the Stone, and will still fall back down with that same force minus what your jump cancelled out.
(All responses are reviewed before being published.)


text:
Give Your Old Tech a New Life at Work
Date: 01-Dec-16
Author: Claire Bell
As the year draws to a close take a look around your office to see the little piles of redundant tech items gathering dust?
It is easier than you might think to de-clutter your office, to get most of these items recycled and, to make the news even better, most of the recycling can be done for FREE!
Here's our tips for giving your old resources new life, keeping in budget and doing something positive for the environment in your workplace:
- Our friends a TechCollect have come up with the brilliant 'Waste Not, Want Not Day' on Thursday 8th December. You can book a FREE pick-up for eligible items (see website for conditions and further information) including: Computers and tablets, Computer peripherals and accessories, Printers, faxes, scanners and multifunctional devices and TVs.
- Alternatively, if you're in a small business, you can search our BusinessRecycling website for other FREE drop off locations under the National Television and Computer Recycling Scheme or to search for organisations who will accept e-waste items not covered by the scheme. Depending on your location and the quantity you may find a free service.
- Old mobile phones and their accessories can easily be recycled through our friends MobileMuster. Find drop-off location near you or follow the links on the page and sign your workplace a collection point.
- If you've got used or obsolete printer cartridges lying around (whether they're empty or full) 'Cartridges 4 Planet Ark' can help. If you just have a couple you can drop them at one of more than 4,000 locations around the country or if you go through more than three participating brand cartridges a month (or the supporting brands) you could get your own collection box. Best of all it's FREE as the participating manufacturers – Brother, Canon, Epson, HP, Konica Minolta and Kyocera – cover the costs.
Modern workplaces can't operate without technology, which inevitably become obsolete. Thankfully there are more ways then ever to stop these useful resources going to waste and recycling in the workplace is becoming a day-to-day practice thanks to schemes like those mentioned above.


text:
Portarlington business group wants ideas
Portarlington PCDA Business Group are appealing for your help.
The non-profit group of business people are trying to help build a better future for all in Portarlington. If you believe you have vision, expertise, ideas and skills than can help make a difference and bring employment to town the group wants to hear from you.
Please send a brief proposal on your vision, contribution and business ideas to email@example.com or drop off to PCDA Office, Catholic Club, Main Street.


text:
Top 9 Healthy Winter Breakfast Recipes to Warm You Up
It is cold outside and you need a little more convincing than usual to get out of bed, try these warm, hearty breakfast ideas to warm you up. We share everyday winter breakfast 9 recipes here. Find easy breakfasts and brunch recipes for the family. #1. Gingerbread oats Make gingerbread cookies but skip the sugar crash and…Read more


text:
Candidate for a Pullet Surprise
I have a spelling checker
It came with my Pea Sea
It highlights for my review
Mistakes I cannot sea.
I ran this poem thru it
I'm sure your pleased to no
Its letter perfect in it's weigh
My checker told me sew.
(with grateful thanks to Dr Jerrold H Zar)
Modern technology is wonderful, and I confess that the spelling and grammar checker on my "Pea Sea" has been used more than once. However, when it comes to important documents – proposals, reports, articles, papers, CVs – nothing can replace the old fashioned proof reader – at least not yet. A well-presented document could make the difference between winning work or publishing a paper – or not.
We offer an editing and proofing service, and we are confident that this, combined with our understanding of technology and industry-specific jargon, will provide you with a technically accurate, well-formatted and grammatically correct document, suitable for any purpose.
For more information please contact us.


text:
|low graphics version | feedback | help
|You are in: World: Americas
Tuesday, 13 February, 2001, 17:48 GMT
Chile court hears Pinochet appeal
A Chilean court has begun hearing an appeal aiming at overturning the house arrest and trial of the country's former military ruler, General Augusto Pinochet.
The general has been charged in connection with the Caravan of Death, a military squad allegedly responsible for the deaths and disappearances of more than 70 political prisoners in 1973.
The appeals court's hearings in the capital, Santiago, are expected to last through Wednesday.
The latest stage in the Pinochet legal saga comes amid new revelations which observers say could make things difficult for the defence.
'Compromising' reply
Last week, a Chilean online newspaper published documents which suggested that the former ruler was aware of human rights abuses being committed against dissidents - these papers will be presented during the hearings.
A handwritten reply, bearing what appears to be General Pinochet's signature, instructs the prosecutor to conclude that no torture took place.
The note adds that Mr Ruiz Tagle was executed because of the serious charges against him.
Analysts have suggested the document could compromise General Pinochet because it proves he did not order an investigation into the matter.
Of the three appeal judges hearing the case, two voted in favour of stripping General Pinochet of his immunity last year, opening the way for a possible trial.
See also:
08 Feb 01 | Americas
Document 'destroys' Pinochet defence
01 Feb 01 | Americas
Pinochet under house arrest
30 Jan 01 | Americas
Pinochet to fight arrest order
23 Jan 01 | Americas
Judge questions Pinochet
13 Jan 01 | Americas
Doctors conclude Pinochet medical
10 Jan 01 | Americas
Finding Chile's disappeared
Internet links:
The BBC is not responsible for the content of external internet sites
Top Americas stories now:
Links to more Americas stories are at the foot of the page.
Links to more Americas stories
|^^ Back to top
News Front Page | World | UK | UK Politics | Business | Sci/Tech | Health | Education | Entertainment | Talking Point | In Depth | AudioVideo
To BBC Sport>> | To BBC Weather>>
© MMIII | News Sources | Privacy


text:
In her new biography, "Henry David Thoreau, " Laura Dassow Walls documents nicely and in detail how deeply engaged with his community Thoreau was, hardly the hermit that is the image many people have of him.
Walls gives us a real sense of the man, along with many of the other hugely influential figures he interacted with, from Emerson to Hawthorne to Margaret Fuller. We also get a feel for life in Concord, an astonishingly hip and humanitarian place for its time, and where Thoreau spent almost his entire life.
Major biographies of Thoreau seem to arrive every two or three decades; the Henry Seidel Canby biography dates from 1939, Walter Harding's biography from 1965, and Robert Richardson's biography from 1986. I've always thought the Richardson biography especially good.
The new Walls biography is a valuable addition to the Thoreau literature. I'd suggest pairing it with Robert M. Thorson's excellent "The Boatman," published only last year, in which he documents convincingly that however much time Thoreau spent at Walden and in the woods, his real love was the nearby rivers, where he spent far more of this time.
The Walls biography only reinforces the image I've had of Thoreau for many years now. He could be difficult, uncompromising for sure, but that did not mean he did not have a large circle of friends and acquaintances, many of whom he interacted with throughout his life, many of whom he had a warm relationship with. Children were drawn to him, and he often led them berry picking, outings that became nature walks. He was close to his family, living with them essentially his whole life, but for his Walden time and trips mostly in New England. Walls makes clear that the Thoreau home, moreover, was a virtual Concord gathering spot. So much for Thoreau the hermit.
Indeed, much of his life Thoreau was either speaking or writing about nature, and social issues, notably slavery, which he opposed with unbending fervor. He spent countless hours walking or rowing his boat, often with others, documenting with grace the flora and fauna of the Concord area and its ecology. He was a remarkably patient and thorough student of the natural world, recognizing long before others, for example, why certain tree species succeeded others after a fire or storm.
Far ahead of his time, Thoreau was calling for nature preserves long before the first national parks and state parks.
His 26-month stay in his little cabin at Walden Pond? Walls calls it "performance art," a clever description, and, even if a little too cute, close to the mark. As Walls notes, "living alone on the pond in ostentatious simplicity, right in sight of a main road, he became a spectacle. It's not clear that Thoreau anticipated this. His original determination to live deliberately and confront only the essential facts of life, voiced so movingly in his earliest days at the pond, show his design to pursue an inward journey, but the accidental circumstances that made that journey possible meant it would be performed on a very public stage." So, maybe we consider it "unplanned performance art."
Walls draws richly from letters to and from Thoreau, journals by others, writings by others. I found her account of Thoreau's lectures over the years especially enlightening. He spent far more time lecturing than I had known, and it shows what a celebrity he had become, most notably after the publication of Walden.
Walls quotes a reviewer in Portland, ME., who wrote, "He bewilders you in the mists of transcendentalism, delights you with brilliant imagery, shocks you by his apparent irreverence, and sets you in a roar by his sallies of wit."
As for "Walden" the book, with its call to live a purposeful, spartan life, embracing the natural world, I can't agree more with Walls that it can be read as a kind of bible, "a new sacred book for the modern age." I've been saying just that for years.
Moreover, I like to think of it as America's greatest self-help book yet.


text:
From my Mother, into the 2013 Amazon Breakthrough Novel Award and made it into the second round in which 2,000 out of a total 10,000 entries over five fiction categories were chosen based on the pitch for the manuscript. Mine was entered into General Fiction.
While my manuscript did not advance to the next round, the quarter finals for which 500 out of those 2,000 were selected based on an excerpt consisting of the first 5,000 words, I did receive the Amazon reviewers' feedback.
Here's what they (names are not disclosed) said:
ABNA Expert Reviewer 1
What is the strongest aspect of this excerpt?
You somehow made me care about running which is something I have NO interest in. I liked the way you worked in bits and pieces from the past both the past of the grandmother and for Nadia.
What aspect needs the most work?
I wasn't really taken with the pitch. If that's all I'd had to read I'm not sure if it would prompt me to read the excerpt or book. It was by no means terrible just a bit lackluster. The thing that caught my attention the most is the mention of WWII Europe. This will sound to minute but your use of the word 'lore' piqued my interest especially in referring to this family. It made me want to settle in for a good story.
I was a little confused about where Nadia lived. At first I assumed because of where she was racing that she lived in Canada but later it seemed she lived in Australia.
What is your overall opinion of this excerpt?
As I said the story was doled out nicely. I loved being inside Nadia's head while she worked on her here and now race and her family's legacy and how that impacts her and better yet what the mystery is and what that will mean. You build great word pictures of both these women. Oma hiding from the Nazi's is suspenseful and scary. I just knew nothing good would come from that. I loved her stubbornness and how it's reflected in her granddaughter. The illustrative story of Christmas in the church and the contest of wills for winning the prized pew seat told volumes about Oma's character and world outlook. She was not going to be taken advantage of again!
All the while I read many questions came to me. Did the Nazi kill or take the child, rape grandma and the child she had was Nadia's true mother? Was this why she seemed estranged from her daughter and her son in law? Why is Nadia so obsessed with running? What is she trying to get away from or to?
I know you're writing general fiction but you've built a wonderful level of suspense into this excerpt!
The use of WWII seems very timely since so much is being written about it today. Personally I can't get enough of fiction and nonfiction about that era and hope the personal stories and the re-analysis continue your book included.
ABNA Expert Reviewer 2
What is the strongest aspect of this excerpt?
What a very haunting, and engaging beginning to this excerpt. We learn a lot about Nadia's character by the way she approaches her running. The scene of the race is so well-written that I feel as though I am right there with Nadia. Oma is a feisty and endearing character; the scene of her pushing the other woman out of her seat in church is hilarious. Oma's history is fascinating, and her relationship with Nadia is appealing and sweet. The rich history of the family, and the hint that there are many parts of the family story that Nadia does not yet know, generate strong engagement in the story.
What aspect needs the most work?
While the portions about running are interesting, they may be a bit lengthy and technical so early in the excerpt, and risk some readers, particularly those who may not be interested in running, becoming disengaged.
What is your overall opinion of this excerpt?
This excerpt captivated me from the start with compelling, well-developed characters and a rich tapestry of family history. The focus on the more technical aspects of running may have been a little overdone for so early in the story, and could risk losing the interest of readers who are not interested in the sport; more early focus on the relationship between Nadia and Oma may help to prevent this from becoming a risk. Overall, however, this was very compelling, and something I would like to read more of.


text:
Wine Harlots
the virtue of vice
by Nannette Eaton on January 8, 2011
"A wind has blown the rain away and blown the sky away and all the leaves away, and the trees stand. I think, I too, have known autumn too long." — e.e. cummings
painting: Lake Zurich by Jan Hackart
Get smart with the Thesis WordPress Theme from DIYthemes.
WordPress Admin


text:
Student And Senior Citizen Discount Airfares
While senior airfare discounts are not as common as they used to be, some airlines still offer them. Based on a member on Platinum status booking one return flight from LHR to Rome departing 05/08/2016 and returning 08/08/2016 for £579.11 including taxes and charges. Some airliners give you discounts on airfare depending on the number of points that you have managed to accumulate by traveling a particular set of miles.
Airlines compete among each other and they can give great flight deals (just know WHEN to look). For increasing sales, promotion or for just getting their flights fully booked; most of the airlines, Banks and Booking sites come up with offers that offer a discount to the flyers while buying a ticket.
This code NEW2FLIGHTwill be valid only on First Flight Ticket Booking of a minimum order value of Rs 3,000. Call 1-800-433-7300 to see if there is a military or government discount for the city you'll be traveling to. See /military for more information. Book your holiday accommodation of worth Rs.3000 or above through Goibibo and avail instant discount up to Rs.3000 OFF + 500 eCash.
Almost all travel agents such as MMT, Yatra, Goibibo announces various promotion codes and discount coupons which offers huge discounts on online flight bookings in India. Yatra users can now enjoy enormous discount on all domestic flight ticket booking using HDFC card.
There are many people involved in a Latin American Studies Course and are preparing for an educational flight to Latin. Discount is not applicable to airfare; Ski, Dive or Globus family of brands including Globus, Cosmos, Monograms and Avalon packages; for groups of 10 or more and is not retroactive.


text:
Job Information
ViacomCBS Internship - Investigative - Summer 2020 in Studio City, California
CBS BUSINESS UNIT: CBS Television Stations
JOB TYPE: Paid Intern
JOB SCHEDULE: Part-Time
JOB LOCATION: Studio City, CA
CBS Television Stations consists of 29 owned-and-operated stations, including 16 that are part of the CBS Television Network, eight affiliates of The CW Network, three independent stations and two MyNetworkTV affiliates. Among its stations are WCBS-TV and WLNY-TV (New York), KCBS-TV and KCAL-TV (Los Angeles), WBBM-TV (Chicago), KYW-TV and WPSG-TV (Philadelphia), KTVT-TV and KTXA-TV (Dallas-Ft. Worth), KPIX-TV and KBCW-TV (San Francisco), WBZ-TV and WSBK-TV (Boston), WUPA-TV (Atlanta), WWJ-TV and WKBD-TV (Detroit), KSTW-TV (Seattle), WTOG-TV (Tampa-St. Petersburg), WCCO-TV (Minneapolis), KCNC-TV (Denver), WFOR-TV and WBFS-TV (Miami), KOVR-TV and KMAX-TV (Sacramento), KDKA-TV and WPCW-TV (Pittsburgh), WJZ-TV (Baltimore), as well as WCCO-TV's satellite stations KCCO-TV (Alexandria, Minn.) and KCCW-TV (Walker, Minn.).
KCBS2/KCAL9 TV, the CBS Owned & Operated Duopoly in Los Angeles, is looking for an Investigative Intern. Participating in the Internship Program you will have the opportunity to experience how a major Broadcast News station runs the News Investigations Unit. There will be opportunities to witness and take part in day to day activities. Internship programs are for approximately 12 weeks and conclude at the end of the semester.
Mandatory skills/experience required:
Enrolled in a full-time accredited college or university, and be an incoming junior or senior.
Must have excellent analytical, communication, and presentation skills
Must have a strong interest in news investigations
Proficient in MS Office applications (Word & Outlook)
Available minimum two and maximum four days a week
Able to drive self to assignments
Participation in the production of Investigative pieces (undercover work possible)
Vetting of story ideas and communication with the public
Working with photographers and/or reporters in the field
Video logging
Cover administrative duties as necessary
Equal Opportunity Employer Minorities/Women/Veterans/Disabled


text:
C3 Push Cart
Full Featured Extras
- Full feature extra deep scorecard holder includes: golf ball storage and smart phone holder
- Extra wide, durable frame
- Simple three-step fold for compact storage
- Easy one-step handle adjustment accommodates golfers of all heights
- Stand and cart bag friendly upper bag bracket with adjustable support arms
- Oversized storage bag
- Integrated beverage holder
- Durable handlebar grip
- Umbrella holder included
- Tee and Ball marker holder
- Lightweight, solid foam maintenance free tires
- Folded dimensions 21.5" x 13" x 18"
- Weight: 15 lbs.
bagboy C3 pushcart
works great , easy roll with rear large wheels. Folds east to a compact size.
push cart
First three wheel push cart I have ever used. Very stable easy to push nicely constructed. Folds up nicely
Great Gift
This gift arrived very promptly and was very easy to assemble. My husband is thrilled with it!


text:
|Sighting Report
|Occurred : 3/18/2012 20:30 (Entered as : 03/18/12 20:30)
Reported: 3/18/2012 7:57:22 PM 19:57
Posted: 5/13/2012
Location: Butler, PA
Shape: Flash
Duration:1 hour +
|Something in the sky tonight
Strange sky night. Various moving blinking lights. What looks to be aircraft lines on several bright lights flowing erratically across the sky. Just random weird stuff


text:
by Al Holman
(Omaha, NE USA)
Stent, friend or foe, I understand the logic for the stent. For the life of me, however, I don't know why money has not been invested for a better design or materials that can be used to bring the tolerance of these devices to be more bearable.
Join in and write your own page! It's easy to do. How? Simply click here to return to Kidney Stent Reviews.


text:
Blog Email Subscription
Who am I?I am Human. Flawed. Passionate. Overwhelmed. Creative. Tired. JoyFilled. Messy. Colorful. Sinful. Redeemed. As a woman living in a world that seems to spin faster with each passing day, I wear more hats than I care to count, but there are a few favorites...I am the wife of an all-too-human Prince Charming and the mother of two beautifully-imperfect children. My soul belongs to Jesus, and He is the reason I am able to find Petals of Joy in this journey I call Life.
Tag Archives: darkness
When I Need to Step Off the Porch
A few weeks ago, during the last half of my spring break, I was at a teacher training. The nerd in me can't get enough learning. Prince Charming Jokes I could be a professional student. He's right. The days filled … Continue reading
Posted in Beautiful Life, Easter, Hope, Joy, Struggles Tagged compassion, darkness, Hope, kindness, Light, mental illness, show up 7 Comments
Dear Momma Fighting Depression,
I know. I know what it's like when the bravest moment of the day is when you crawl out of bed. I know what it is to stand in the shower longer than you should—willing yourself to face the day. And … Continue reading
Posted in Struggles Tagged darkness, depression, Light, Sisterhood 7 Comments
Getting From One Hard Day to the Next
From the Archives…Because today? This past week? I needed the gentle reminding of His whisper. Crowds of tourists with fanny packs, flip-flops and sunglasses. The Florida sun beat upon my nose, leaving its lobster-like stain on my pale skin. The … Continue reading
When You Need a Do-Over
Some days I just need a do-over. A can-I-take-it-back kind of day. Days when the mommy guilt rubs my heart raw. I'm exposed, bleeding from expectations I set, yet can never meet. And if I'm honest, right now I need … Continue reading
Posted in Joy, Motherhood, Relationship with God, Struggles Tagged darkness, depression, Joy, lies, Light 7 Comments


text:
15 Festive Christmas Printables
Vacation fancies and frills don't should be costly. In truth, with some paper and ink, it's very straightforward to create your personal Christmas cheer. You're in all probability considering "However I'm not an artist!" Neither am I. Because of some superior individuals across the globe and the Web, there are some pretty artistic printables to place the festive in Christmas! Take a look at these 15 festive Christmas printables and see for your self.
Pleasure to the world! Unfold Christmas cheer round your property with this free Christmas carol lyrics printable. It should make you need to sing each time you see it. (by way of Lil' Luna)
There's nothing cozier than a chunky knit sweater on a chilly snowy day. These present tags definitely evoke emotions of coziness, it doesn't matter what colour the wrapping paper is. (by way of Eat Drink Chic)
In a season of flashing lights and fixed carols and inboxes filled with gross sales, typically you need nothing greater than a silent night time. This easy printable card is good, together with a reasonably message in a non-fussy means. (by way of Delilah Creates)
Everybody has seen this basic Christmas story, whether or not on stage or on TV, and this quote brings to thoughts that little boy on crutches who nonetheless wears a smile. Definitely a worthy quote to show at Christmastime. (by way of Sweet C's Designs)
Even your cubicle deserves some vacation spirit throughout this sparkly season. Add a few of that sparkle and shine with this little printable banner. You'll need to eat lunch in your dice the entire vacation lengthy. (by way of Classy Clutter)
Now you may give the partridge in a pear tree for Christmas with these lovely playing cards. Whether or not that's a partridge or truly a quail, I'll depart it as much as you to determine. (by way of Etsy)
"Have your self a merry little Christmas" by no means was so applicable as this little purple buggy with slightly inexperienced tree on prime. It's festive, it's household pleasant and it's simply plain tremendous lovable. (by way of Craftberry Bush)
Christmas villages might be costly and troublesome to show. Until you set it on paper! This printable village impressed by Anthropologie will brighten up any mantle or bookshelf this yr. (by way of Thoughts from Alice)
It's all the time enjoyable to discover a new stylish Christmas one thing that isn't pink or inexperienced. This purple watercolor card is sudden and guarantees to be in entrance of all of the others in your good friend's vacation card show. (by way of Etsy)
Chalkboard is cool. Banners are cool. Put them collectively for the Christmas season and also you've instantly received the epitome of wonderful, proper? (by way of Just Destiny Mag)
Do you've gotten a countdown till Christmas? Make it a flowery one with these classic-impressed printable tags. Select some ornaments off the tree or go purchase some matching units to make this countdown extra enjoyable. (by way of Ella Claire)
Christmas ought to be all about pleasure! Pleasure for our household and pals. Pleasure for all our blessings. Pleasure for our new child Savior. Present the enjoyment with these fairly blue printable playing cards. (by way of Etsy)
Whether or not you could have sparkly shiny playing cards or easy ones, festive envelopes will deliver a smile earlier than their even opened. In truth, you'll be spreading that Christmas cheer to the mailman too! (by way of This Heart of Mine)
Stylish presents for stylish associates deserve stylish present tags. These chalkboard takes, sprinkled with purple and inexperienced holly and delightful typography, undoubtedly gained't fail you. (by way of Lia Griffith)
Let your youngsters in on the Christmas card motion with these pleasant printable playing cards. Being black and white, you'll be able to set these little fingers free with crayons, markers or pencils to make distinctive playing cards for everybody. (by way of Mr. Printables)


text:
From September 27-October 3 this year we are celebrating "Banned Books Week"
(to add "I Read Banned Books" to your profile pictures click here.)
I'm so glad that our friends at Grown Up Fangirl alerted me to Banned Books Week this week!
If you were like me and didn't know what Banned Books Week is, here is a little information.
(more information and lists of Banned and Challenged books, visit ALA.org)
From the ALA website:
"Banned Books Week is an annual event celebrating the freedom to read…Banned Books Week brings together the entire book community—librarians, booksellers, publishers, journalists, teachers, and readers of all types—in shared support of the freedom to seek and to express ideas, even those some consider unorthodox or unpopular…
Banned Books Week draws national attention to the harm of censorship… While books have been and continue to be banned, part of the Banned Books Week celebration is the fact that, in a majority of cases, the books have remained available. This happens only thanks to the efforts of librarians, teachers, students, and community members who stand up and speak out for the freedom to read"
I understand why many people (especially parents) want certain books banned from school reading curriculum, libraries, and other shelves. There are some YA books that I have read as an adult with themes and scenes that I would rather my daughter didn't see until she was closer to 16-18. But those are discussions that will happen in our home later on. (she's only 2 now. haha)
Let book restrictions happen in each individual home, rather than trying to limit opportunities for everyone to read certain books.
Click here to see the top 100 banned books:
Click here to see Banned and Challenged books by year:
Banned Books post on @FoldedPagesDistillery Instagram


text:
What's the difference between type 1 and type 2 diabetes? An interesting yet critical question we should answer. Diabetes is common yet life-threatening health condition that everyone has to be aware of.
According to CDC, more than 29 million people in US have diabetes and the trend shows that more people are suffered now from time to year. Diabetes also known as diabetes mellitus is a particular condition of metabolic disorder where human body cannot store and use sugar properly.
It happens due to the fact that the body is no longer producing enough insulin. Insulin itself is an important property that functions to regulate blood sugar and use it as energy. It is produced by pancreas.
In serious conditions, diabetes is strongly linked to serious diseases including neurological condition, cardiovascular disease, vision loss, damage to organs and blood vessels and kidney disease. There are two types of diabetes, the type 1 diabetes and type 2 diabetes.
Each type is unique and different as it has its own causes, risk factors and also lines of treatment. Once a person is diagnosed with diabetes, the doctor should tell which type of diabetes the person has so the patient can get the right treatment.
Facts on Type 1 and Type 2 Diabetes
Before we get on the detailed differences between type 1 and type 2 diabetes, learning some facts on these two different types of diabetes might be useful. The type 1 diabetes often comes as unpreventable and hereditary condition.
Type 2 diabetes is often not hereditary condition yet it is more common. With 1 people having type 1, there are 20 people having type 2 diabetes. The most common causes of type 2 diabetes include unhealthy diet increase, lack of exercise and excess weight.
Once a person is diagnosed with type 2, he/she often has to live with this condition in his/her lifetime. Despite some differences, both types also have similarity including the fact that the condition can lead to possible amputation of limbs, kidney damage, nerve damage, stroke and heart attack.
Causes of Type 1 and Type 2 Diabetes
In type 1 diabetes, a person is diagnosed to have the related condition when the body's mistakenly immune system attacks the pancreatic beta cells responsible to produce insulin.
It destroys the cells and reduces the ability of the body to produce sufficient amount of insulin to regulate levels of blood glucose. In the end, the body is no longer producing insulin.
Therefore, the person having this diabetes requires supplemental insulin. It can happen to anyone in any ages including children, young adults and adults.
In type 2 diabetes, the cause is a different to type 2 diabetes. Type 1 diabetes cause is related to the facts that body's cells become resistant to insulin's effects.
If it is left untreated, the body stops insulin production causing the body to no longer have the ability to effectively use glucose.
This condition is often known as insulin resistance where calls become unresponsive or less responsive to insulin. It takes years for the symptoms to appear. And once a person is diagnosed with type 1 diabetes, he/she should use medications, change their diets and do regular exercise.
Risk Factors of Type 1 and Type 2 Diabetes
Genetic factors play role in both types of diabetes. Scientist have discovered in type 1 diabetes that a certain number of genes linked to this health condition and happen to some people but not everyone. In type 2 diabetes on the other hand, the key role is related to family history.
More complicated risk factors play role in type 1 diabetes which are viral infections including rubella cytomegalovirus and mumps. Meanwhile, type 2 diabetes is highly related to genetic influence, bad diet, obesity, inactive lifestyle and aging.
According to some research, people having low vitamin D levels are more prone to both types of diabetes. This is because vitamin D has role to support insulin sensitivity and immune function.
Diet also plays key role in both types of diabetes. According to studies, people who started to drink cow's milk at earlier age are more prone to type 1 diabetes. Therefore, doctors recommend women to breastfeed longer to reduce the risk. Type 2 diabetes on the other hand is more common in families struggling with obesity and having similar bad exercise and eating habits.
Development of Type 1 and Type 2 Diabetes
With different cause and risk factors, both types of diabetes have different development stage.
Type 1 diabetes is known as autoimmune disease because of how immune system mistakenly attacks the beta cells in pancreas. This type can develop at very early age like childhood with unknown cause. And, its development can be very fast that takes only few days or weeks.
Those with this diabetes type are required to inject insulin in their body in regular basis to compensate for non-existence of beta cells. Unlike type 2 diabetes, this type isn't linked to excess body weight but to higher ketone levels.
Type 2 diabetes on the other hand has different development stage. This type is caused by insulin resistance. Its development stage tends to be longer than type 1 diabetes such as in people who are more than 30 years old.
In fact, it can take years for the symptoms to appear and a person to be finally diagnosed with diabetes. This type is highly associated with high blood pressure, high cholesterol level and excess body weight.
In type 2 diabetes, insulin injection is required in regular basis because of two main reasons. The first reason is low sensitivity to insulin due to excess body weight. Injection is necessary to prevent hyperglycemia. The second reason is beta cell failure to regulate blood glucose level. So, insulin injection is required.
Can a Diabetics Eat Banana ?
With those detailed differences on type 1 and type 2 diabetes, it's clear to see that each type requires certain particular diabetes treatment and medications. Although both types cannot be cured but medications are necessary to control the condition so it doesn't get worse.


text:
Back with More Names for the Faces
October 11, 2013
I've been AWOL for almost a month…my apologies! September was very busy, but I'm back and ready to fill in some blanks for the pictures I've started posting from my Dad's WWII photo album. Here's a picture from the 224th while they were training in Florida during the summer and fall of 1943.
A note on the front of this shot said "Koski-Dement-Goodman" "Clermont Fla, Oct. 1943". Dad's words on the back tell a much richer story; "Three bosom buddies left to right: S/Sgt George Koski, used to be T/4 Dement & T/4 Goodman. They're swell guys. Koski is a high speed operator & he really can send it. Taken in Orlando". The unit roster list Dement, A.B.(IO), initials only, and Goodman, Ulys D. George Koski does not appear in the December 1943 rosters. Also notice Koski is referred to as an "high speed operator"; these are communications teams, they used field phones, two-way radios and a telegraph key. So my Dad is talking about Koski's ability to send Morse code on a key; not easily done by most people.
Looking closely at the background and surroundings we can see a tarpaper-covered building that may be the battery building or a barracks. Other shots from this area show pyramidal tents on frames commonly used to billet troops. In the foreground above the buddies heads you can see a bit of Spanish moss hanging from the tree to give that "bayou" feel!!!
Note: this image was taken 70 years ago this month.


text:
Please enter the following information as it appears on your credit card statement. This will not be shared of used in any fashion other than to track and deliver your leads to you.
This site is secured via 256-Bit encryption
To ensure you receive leads exclusive to your opportunity, please select your business from the list below. If your organization is not listed, select 'Not Listed'.


text:
On 23 June 2016 Wall Street Journal published an article that raised the question is Virtual Reality the next frontier in Marketing? On 24 June 2016 Cool pad came in news when it launched its VR 1x Virtual Reality head set only for ₹999 ($15 Approx). Global VR market is expected to be of $120 billion by 2020 but what is Virtual Reality? VR can take you to the grassy fields of Scotland while you're at home. VR can give you experience of a roller coaster ride while you are sitting on your sofa. All this can be done in the world of Virtual Reality, where the impossible becomes possible. It is taking over the world by storm with the advent of many products like the Oculus, Google glass and Samsung Gear VR. Read more to know about Virtual Reality concepts in simple words.
What is Virtual Reality?
Virtual reality (VR), is a computer technology that replicates an environment, real or imagined, and simulates a user's physical presence and environment in a way that allows the user to interact with it. It is an emerging trend which is now bringing more public attention.
In more simple words VR makes you to see things or places around you that don't really exist but looks so real, it almost (if not actually) makes you feel like you are right there in the action.
Benefits of Virtual Reality :
Virtual Reality is fun and extremely tempting to try and enjoy for many people. It gives a new perspective for people in the field of entertainment and education:
1. Entertainment
The main reason for Virtual Reality is for entertainment purposes. The financial growth of this area can be calculated from Global Virtual Reality Industry Report 2016 report of Research and Markets. There are so many ways to have fun in virtual environments. Disney brings movies to life with Disney VR movies. Along with VR movies, there are several new games that uses head mounted displays to give an immersive feel for the users. Some games to note are Chronos, Valkyrie, and The Climb. They are powered by Steam, an entertainment platform. The VR cinema in Amsterdam now provides a 360 degree movie experience to people by giving them an almost real life movie that unfolds around you! Click here to watch the video of VR cinema.
- Prev
- Next >>


text:
"In the early days, his passions were....LSD and Marxism. Later he moved more into goofy pseudo-Jewish liberation theology and hatred of Israel..."
"In the early days, his passions were....LSD and Marxism. Later he moved more into goofy pseudo-Jewish liberation theology and hatred of Israel..."
Poor Poor Michael Lerner's Petunias!
by Professor Steven Plaut
Michael Lerner's home vandalized!
Lerner's own organization's website has the scare headline: "A Right-Wing Zionist Threat: Vandals Strike Tikkun Editor's Home [1]." Leftist bloggers have been even less restrained. The Zionists are violent thugs and hoodlums, Judeofascists, vandalizing [2] the home of Tikkun's editor and and threatening him. The "attack" on Lerner's house in the upscale Berkeley Hills was a direct consequence of criticism from Alan Dershowitz–more proof that foolishly allowing non-leftists to exercise freedom of speech results in violence and hooliganism!
So just what exactly happened?
Lerner, a leading collaborator in leftists' wars against the Jews, is anti-Israel and pro-Palestinian. He calls himself "Rabbi," although he never graduated from any rabbinic seminary and has no rabbinic ordination recognized by any branch of Judaism. His Tikkun Magazine, publishes every Jewish anti-Israel crackpot and crank on the planet and many a non-Jewish anti-Semite. In recent weeks, Lerner made the news for organizing a petition of anti-Israel leftists to support Judge Richard Goldstone [3] and even offered to grant him an award. Goldstone had headed the UN commission that smeared Israel for "war crimes" when it was forced to go to war against Hamas to stop its rocket attacks. Since issuing his libelous report, Goldstone has been shunned by the Jewish communities all over the world, including in his own native South Africa, where some members of a synagogue where Goldstone's grandson was having a Bar Mitzvah declared him persona non grata.
At that point, Prof. Alan Dershowitz, who considers Goldstone an anti Semite, denounced [4] Lerner for his toadying to the jurist and [5] denounced the petition circulated by Lerner as coming from "Rabbis for Hamas":
"They have no shame and no credibility. They exploit their rabbinical status to support any conclusion that undercuts self defense Israeli actions without regard to the evidence and without regard to the truth. Not surprisingly, the worst of these rabbis (and that's saying a lot), Michael Lerner, after attempting to politicize the bar mitzvah by offering his anti-Israel synagogue for the event, has decided to honor Richard Goldstone with Tikkun Magazine's 'Ethics Award.' I guess all it takes to be honored by Tikkun is to pass Lerner's litmus test of lying about Israel. That's Lerner's definition of 'ethics.'"A few days ago, some anonymous people, evidently Jewish students at the University of California at Berkeley, paid a visit to Lerner's home up in Berkeley Hills. (Just how Lerner came up with the cash to live with the capitalist class in one of the ritziest locations in the Bay Area is something about which his magazine readers might be wondering.) The visitors taped up four stickers or leaflets around his home Here is the Tikkun version [6] of the story:
"They posted a printed bumper sticker saying 'fight terror — support Israel'" next to a caricature of Judge Goldstone whose UN report on Israel's human rights violations in its attack on Gaza last year has been denounced as anti-Semitic and pro-terror by right wingers in Israel and the U.S. The caricature has Goldstone talking about his being kept from his grandson's bar mitzvah, and the caricature of Rabbi Lerner responds by saying 'any enemy of Israel is a friend of mine.'"Lerner of course called in the cops. You know – those civil servants whom he used to refer to as The Pigs when he was a leader of the Seattle Liberation Front (SLF), a 60s group which participated in numerous violent anti-war protests and riots along side the Black Student Union (BSU) and the ultra-violent Weatherman [7] terror group. When the cops arrived they found a victimless non crime. The leaflet hangers did not assault Lerner, and in fact never met or spoke with him. They did not so much as trample on the petunias in his yard.
But Lerner and his supporters are having trouble containing their rage. The perps of the leaflet hangings are Zionist terrorists, thugs, vandals! Some political observers in the Bay Area are expressing skepticism. At least two local pro-Israel activists told me they suspect Lerner himself put up the leaflets in order to play martyr and get himself publicity. Lerner has a track history of what might be called strategic misrepresentation when it comes to getting himself attention. A few years back he got caught inventing pseudonymous imaginary letters [8] to the editor printed in Tikkun Magazine agreeing with Lerner's own writings there. (One wag claimed he should have signed them Ichael-May Erner-Lay.)
Lerner's whining about being the victim of "Rightwing Zionist violence" is also a bit beyond hilarious. Lerner himself has a long track record of organizing and participating in violence. While he was in Seattle, Washington state attorney (and later Senator) Slade Gorton described [9] the tactics of Lerner's Liberation Front as "totally indistinguishable from fascism and Nazism." Lerner himself was one of the so-called "Seattle Seven," charged in a federal trial with "conspiracy to incite a riot." He spent several months in prison.
In those days Lerner's two passions [10], by his own admission, were LSD and Marxism. Later he moved more into goofy pseudo-Jewish liberation theology and hatred of Israel. He considers the rebirth of international anti-Semitism to be the fault of the Jews themselves for being so cussedly evil and racist.
He launched the bizarre magazine he called Tikkun in 1986 and has devoted it to radical politics, bashing Israel, and denouncing America, along with a monthly dollop of New Age touchy-feely recreational "compassion" and peace posturing.
Around the same time that he launched his magazine Lerner started telling people that he was an Orthodox Rabbi. In fact he is neither a Rabbi nor Orthodox. He says he was "ordained" when three hippy "rabbis," one of whom claims in fact to be a Buddhist, put their hands on his head and proclaimed him rabbi. A few years back I emailed him an inquiry as to whether he would submit to a small quiz of his knowledge of the Bible and the Talmud; he indignantly refused. He claims his rabbinic status is recognized because he is a member of the California Board of Rabbis. But membership in the Board does not mean anyone has acknowledged one's rabbinic credentials as bona fide; it just means one pays annual dues.
While insisting that all he wants is peace and justice in the Middle East, Lerner's prescription for achieving this is essentially the same as that of the Hamas. He demands that Israel return to its 1949 borders, forego all forms of self-defense, and allow itself to be drowned by an influx of Palestinian "refugees." Lerner has never seen an act of Arab terrorism that he does not rationalize, nor an act of Jewish self-defense he is willing to justify. Lerner recently hosted Alice Walker [11] on Yom Kippur, who devoted her talk to denouncing Israel for raping Arab women.
Besides Israel bashing, Lerner may be best known for sharing his "politics of meaning" (his nonsense term for disguising leftist politics under a thin veneer of theology) with a credulous Hillary Clinton when she was First Lady. After 9-11 he demanded that Americans "feel the pain" of the al-Qaeda terrorists. While claiming to be a rabbi he has also issued calls [12] to "Smash the Synagogue." When Professor Edward Alexander from the University of Washington wrote an expose of Lerner, the latter sent threatening letters to numerous Jewish newspapers and magazines, warning they would be sued by him if they printed the piece. Professor Alexander has described Lerner as "a kipah (skullcap)-wearing, rotund beard-plucker of vaguely 'rabbinic' appearance who could always be relied on to blame Israel and not the Arabs for the absence of peace, and to liken Israeli defense against Palestinian Arab violence to medieval Christian mobs . . . organizing pogroms against the whole Jewish community."
A few years back Lerner demanded that all Jews devote their traditional Passover Seder to bemoaning the oppression of the Palestinians by the Zionist "Pharaoh." The same Palestinians used the occasion that year to murder 29 people at a Seder in Netanya, Israel. He has long supported sanctions and boycotts against Israel to force it to capitulate to the Arabs. He considers Arab terrorists to be the "New Maccabis," and his writings are routinely carried by the publications and distribution lists of Islamic fundamentalists – the sorts of people who support car bombs in Times Square.
This is the man victimized by the merciless violent "terrorist vandalism attack" by Rightwing Zionist thugs against his home in Berkeley that spared even his petunias.
URLs in this post:
[1] A Right-Wing Zionist Threat: Vandals Strike Tikkun Editor's Home: http://www.tikkun.org/tikkundaily/2010/05/03/right-wing-zionist-threat/
[2] Judeofascists, vandalizing: http://blogs.alternet.org/speakeasy/2010/05/04/judeofascists-attack-home-of-progressive-rabbi-michael-lerner
[3] support Judge Richard Goldstone: http://www.daylife.com/topic/Michael_Lerner
[4] Prof. Alan Dershowitz, who considers Goldstone an anti Semite, denounced: http://cgis.jpost.com/Blogs/dershowitz/entry/it_is_goldstone_who_is
[5] toadying to the jurist and: http://mondoweiss.net/2010/04/rabbinic-letter-to-goldstone-your-report-is-a-clarion-call-to-israel-and-the-jewish-people-to-awaken-from-the-slumber-of-denial-and-return-to-the-path-of-peace.html
[6] the Tikkun version: http://www.tikkun.org/article.php?story=vandalism
[7] Weatherman: http://www.discoverthenetworks.org/groupProfile.asp?grpid=6808
[8] he got caught inventing pseudonymous imaginary letters: http://www.jweekly.com/article/full/5319/
[10] Lerner's two passions: http://www.discoverthenetworks.org/individualProfile.asp?indid=632
[11] recently hosted Alice Walker: http://www.beyttikkun.org/article.php/20090929072148570
[12] he has also issued calls: http://www.wernercohn.com/Resources/Reflections%20on%20Apostasy.pdf


text:
IBC Submission Process
- What is the submission process?
- Who can register?
- What needs to be registered?
- Special instructions for Clinical Trials
- When do I need to be registered?
What Is the Submission Process?
Prior to starting work with recombinant and synthetic nucleic acid molecules, microorganisms, and/or biotoxins, the Principal Investigator will electronically submit an application to register the agents.
Use eProtocol, our electronic application system for IACUC/DLAR/IBC, to submit an IBC application.
Instructions for eProtocol (DOC)
Active use of recombinant or synthetic nucleic acid molecules, microorganisms, and/or biological toxins:
Your IBC application will be reviewed at the next monthly IBC meeting (submission deadlines).
As part of the IBC review process, the investigator will also require to:
- Take biosafety training (all personnel on the protocol also have to take this training)
- Have a lab inspection of all the facilities used for the project. Call the BSO at 843-792-3125 to schedule.
- Prepare a safety protocol for the agent(s) being registered
Storage of microorganisms and/or biological toxins:
All microorganisms (including viral vectors, bacteria etc.), irrespective of risk group, that are not actively used in research but held in storage, need to be registered with the IBC. Biological toxins also need to be registered.
For eRMA, please follow the abbreviated process for registering stored-only agents. This registration will serve to keep inventory of stored-only agents, which will be reviewed administratively only.
For eProtocol, please follow instructions for IBC submission through eProtocol (DOC).
A 'storage-only' registration will need to be updated if agents become actively used or if agents are disposed of.
Only MUSC faculty are eligible to submit IBC applications. Post-doctoral fellows, graduate students, and visiting faculty must have the faculty member with whom they are working submit applications covering their work. The faculty member must be registered in the Provost's Office Faculty Database to be able to submit on the Electronic Research Management applications System (ERMA).
MUSC IBC approval must be obtained to use the following for research:
- Recombinant DNA (rDNA)
- Microbes [Risk group (RG) 1-4] (including agents on the Select Agents list)
- All biological toxins (including toxins on the Select Agents list)
The IBC requires registration of research involving the isolation, culture, or manipulation of known bloodborne pathogens (e.g. in blood, tissues, or cells). It is expected that investigators follow the Office of Risk Management's Blood Borne Pathogen Exposure Control Plan (PDF) for all other work involving human biological materials.
Clinical Trials
For research involving administration of these products to human subjects, special instructions apply for submission through eProtocol to the IBC.
Applications must be submitted prior to the initiation of work with the agent(s) being registered. The IBC meets monthly and submission deadlines are three weeks before the meeting. Submissions should be done in a timely manner as needed to permit:
- Submission of grant proposals
- Release of funds for approved proposals
- Achievement of a satisfactory laboratory inspection conducted by the Institutional Biosafety Officer (BSO) as required for IBC approval. Call 792-6521 to schedule
- Release of approvals from other regulatory committees (IACUC and IRB) requiring IBC approval for their applications involving use of agents registered by the IBC.
Periodic Reviews
- Approved protocols in eProtocol are active for three years and require annual continuing review. After the 3rd year, the PI will need to submit a new IBC application in eProtocol. The IBC may determine that the research risk is of significant magnitude meriting review more frequently than on an annual basis. Prior to a registration's expiration date, the IBC staff will send the Principal Investigator a timely reminder of approval expiration.
Amendments to registrations must be submitted prior to making a change in personnel, agents, procedures/practices, and facilities.


text:
Click on the image to return to article
The grey Lamborghini Jalpa feels right at home in this company ... getting ready to put down a time on the drag strip
Photo copyright J Brezic Photography
Original resolution of 1280x853px shown
LamboCLUB resolution : 2400x1600px
Note : All information and images found on this site are copyright protected by their respective owners and are used for review purpose only, nothing found on this site may be reproduced in any form without prior consent from the actual owner. Please feel free to take a look at the copyright information and the legal disclaimer for more details on these issues.
Added on Jul 1. 2013
FileSize : 361 Kb
Downloads : 4000


text:
Rega Turntable Mats
Rega Fono Mini A2D
Rega Wall bracket for all Rega decks
Rega Elys2 MM Cart
Rega Fono MM Phono Stage
Rega TT PSU Neo NEW Turntable Power Supply Unit
Rega P1 Turntable
Rega Fono MC Phono Stage NEW
Rega Research Exact MM Cartridge
Our Website uses cookies to deliver our services better. By using our website, you agree to our use of cookies. Click here to know more about our "Privacy & Cookies Policy".


text:
Translation Left To Anyone Wishing To Have A Go!
Mine would be "I need some warm weather"!
Mine would be "I need some warm weather"!
He is shouting 'Yahoh!' The query after the characters indicates that it is not Japanese. My best guess is he is trying to say 'Yahoo!'
Or - it could be a message to Al Gore:
'Ya whore!'
The latter, Edgar!ReplyDelete
What a lovely banner photo.
Anyway I'll send this to my Chinese speaking family member. Don't expect a quick response though. :)


text:
Please use the form below to submit any questions, concerns, suggestions or requests concerning our services.
We will respond to your messages as soon as we can. If you require immediate assistance, please contact us by phone: 519-256-4914.
Monday - Thursday: 8am - 6pm
Friday: 8am - 5pm
Saturday: 8am - 12pm
1568 Ouellette Ave., Windsor, ON N8X 1K7
Copyright © 2020 Clear Medical Imaging. All rights reserved.
Web Design & Development by Douglas Marketing Group


text:
A risk factor is something that raises your chances of getting a health problem.
Kidney stones are more common in people who have had them before. They also tend to run in families.
The chances of kidney stones are also higher for people who:
- Are White or Asian
- Are under 40 years old
- Had stones develop when they were a child
- Had certain types of stones such as uric acid or those caused by an infection
- Have certain problems with their genes that make stone formation easier
- Take certain medicine such as allopurinol, penicillin, vitamin C, or loop diuretics
- Do not drink enough fluids—this may be more of a problem in warm climates
- Have high intakes of:
- Oxalates—found in berries, spinach, rhubarb, chocolate, or tea
- Salt
- Calcium—can also happen with not getting enough calcium
- Vitamins C and D
- Have health problems such as gout, obesity, how the body uses insulin, or an overactive parathyroid gland
Revision Information
- Reviewer: EBSCO Medical Review Board Adrienne Carmack, MD
- Review Date: 03/2019 -
- Update Date: 04/01/2019 -


text: Industry experts offer an inside look at the current state of positioning technologies for bio-related microscopy. Positioning systems and equipment are sometimes the unsung heroes of microscopy: Users often focus more on the optics and the light sources than on the devices that keep the rest of the system stable enough for death-defying feats of resolution and imaging depth. But that stability is vital – without it, further advances in biological research might not be possible. BioPhotonics reached out to major players in the industry to gain some insight into how the positioning market is doing at present and where it's going in the future. The company reps we interviewed were: Stephan Briggs, a biomedical engineer at Edmund Optics in Barrington, N.J.; Alexandra Cooper, director of sales and marketing at Sutter Instruments in Novato, Calif.; Robert S. Hodge, president of Siskiyou Corp. in Grants Pass, Ore.; Malcolm Minty, general manager at New Focus in Santa Clara, Calif.; Stefan Vorndran, vice president of marketing at PI (Physik Instrumente) LP in Auburn, Mass.; and John Zemek, executive director of ASI/Applied Scientific Instrumentation Inc. in Eugene, Ore. Q: What do you see as the "next big thing" in positioning for bio? Are you seeing any new and exciting advances coming out of R&D and/or university labs? ASI's diSPIM (dual inverted selective-plane illumination microscopy) system was developed in collaboration with Dr. Hari Shroff of the NIH/NIBIB. Courtesy of Applied Scientific Instrumentation. Zemek: Superresolution microscopy and selective-plane light-sheet microscopy are the next big thing. The superresolution scopes require very stable positioning stages, and the light-sheet scopes require precise positioning control of a number of axes, including syncing the positioning of the laser/light-sheet position via micromirrors with the imaging objectives that are mounted on piezos. We have been working with Dr. Hari Shroff at the NIH/NIBIB (National Institute of Biomedical Imaging and Bioengineering) for the last few years to develop a dual inverted selective-plane illumination microscopy (diSPIM) system. This system is 30 times faster than standard confocal systems and is very efficient with photons, so there is very little photo-bleaching or phototoxicity. This makes it a perfect system for long-term live-cell experiments. Hodge: High-resolution 3-D imaging is really the latest big thing and is the combination of photonics and the life sciences coming together. The next step will be to integrate that technology into commercial application, and will require highly precise and stable mechanical devices (optics mounts, linear stages and motorized drives) to enable consistent day-in, day-out operation that is demanded at the commercial level. Piezo-based nanofocus devices such as the PI PIFOC are often used in superresolution microscopy, fluorescence microscopy, drug discovery and 3-D imaging. Courtesy of PI (Physik Instrumente) LP. Minty: We see a move to more benchtop instruments that have a more compact optomechanical layout. This often requires integrated precise, remote adjustments that were previously done by manual stages or mounts. Vorndran: Microscopy, sequencing and screening applications have a higher demand for throughput and precision at the nanometer level. Nanopositioning devices are used in fast nanofocusing, beam-steering and 3-D cell imaging applications. Nanodispensing – extremely precise dosing of liquids based on precision motion control at the nanometer level – also becomes more important in drug discovery applications. Briggs: Actuators and motorized stages for biomedical and life sciences applications … are still expensive. Once the price comes down, I expect more to be integrated into systems and applications at the research and production level. Cooper: Mechanically, we see improvements in positioner design made possible by higher-accuracy five-axis machining centers. Tighter tolerances make for higher precision in the instrument. The biggest changes are not mechanical: Better user interface designs and tighter integration with imaging and data acquisition software are making positioning products easier to use. Siskiyou Corp. offers mounts such as the IXF10i, seen here with clip, and also offers DC servo drives and high-resolution adjustment screws. Courtesy of Siskiyou Corp. In bio, we were excited about the implementation of the first imaging-based brain-machine interface using two-photon calcium imaging, which paves the way for paralyzed patients to directly control devices (e.g., wheelchairs, robot arms, computer cursors) using brain activity instead of invasive electrodes. Q: How would you say the market has been in the past few years for positioning for bio? Where is the market going? Hodge: Positioning requirements continue to be more and more demanding with the development of new techniques. The reduction of NIH funding the last few years has made this tough for the university researcher, but they are a resilient group and figure out unique ways to solve their funding and mechanical problems. New Focus offers piezo-based nanopositioners including the Picomotor and Agilis from parent company Newport. Courtesy of New Focus. I think electrophysiology has a long future ahead, though technology may change that: Think DNA sequencing. On the commercial side, technologies like 3-D imaging and even the use of electrophysiology will move into the pharmacological and imaging applications. Briggs: In my perspective, the market has been at a bit of a standstill. There have been minor developments in positioning and mechanics for cryogenic and vacuum applications, as well as translation stages that are pushing the envelope in terms of precision and speed, and isolators capable of dampening even the most extreme working conditions – but these are simply improvements upon existing technology. There hasn't been a truly groundbreaking development or release in the past few years. Zemek: The market has become more demanding; new applications such as superresolution microscopy require more precise and stable stages. The market is heading for higher resolution, so the trend will continue to push the limits of precision and stability. The Quad is a four-axis micromanipulator that offers drift-free fine control of electrode positioning. Courtesy of Sutter Instruments. Cooper: Positioning instruments have become more of a commodity product as electrophysiology and microscopy have moved from pure research to being a tool used for cellular assay. Our customers now see our instruments as a means to an end and have less time to devote to learning techniques. Ultimately, bundled systems and software with more automation will begin dominating the market. Vorndran: We see a higher demand in smaller and higher-accuracy positioning devices. Minty: [The market is] growing rapidly as increasingly more instruments are automated or have remote servicing and adjustment that previously required a visit from a service engineer. We anticipate continued growth as integrated adjustments come down in cost of ownership and in footprint inside. Q: What are the biggest challenges to advances in positioning for bio? Vorndran: Cost and size. A recent breakthrough in several piezomotor-related drive technologies allows the production of extremely small devices, with longer travel ranges and at lower cost than before. The open-loop Zaber Motorized X-Y Microscope Stage features accuracy and repeatability, as well as quick translation speed across 100 × 120 mm of travel. Courtesy of Zaber and Edmund Optics. Briggs: There are a lot of companies working in this area, but many of the larger companies known for mechanics or positioning have other focuses. Positioning is sometimes an afterthought or secondary. Hodge: The biggest challenges at the university level will be funding high resolution and precision for laboratory applications, as the devices required are not inexpensive. As techniques merge into commercial applications, this does change as volume goes up, but entry level can be steep. Another challenge is precision, stability and the desired ever-shrinking size of commercial devices – there are physical limitations that, with current technology, can be major roadblocks. I still believe in our abilities to resolve these issues even with limited funding. Minty: [One challenge is] making designers aware of the advances in the technology. It also involves looking at the overall performance advantages of precision adjustments and reduced cost of ownership vs. more expensive components upfront. Cooper: NIH funding levels certainly are not what they were 10 years ago. In order to help customers stretch their dwindling grant money, we have tried to offer customers more flexible products with more functionality, which makes for better equipment investments. We also have started offering bundled systems that allow us to give larger discounts and thus offer more value to the researcher. Zemek: [Two big challenges are] thermal drift and stability over time. ASI was one of the first companies to develop a continuous reflective interface feedback focus (CRIFF) system for maintaining focus over time; this has been replaced with our CRISP system. Similar systems are commonplace today, as seen with Nikon's Perfect Focus, Olympus' ZDC and Zeiss' Definite Focus. Maintaining X-Y position over time with embedded nanoparticles, or other fixed fiduciary, is a logical next step for superresolution work. Q: And which application areas would you say are thriving – and why? Minty: The life sciences market, because customers want lower-cost and smaller systems. Briggs: There are a number of biomedical and life sciences applications that are demanding the most advanced positioning products. These include confocal and multiphoton microscopy, optical coherence tomography, point-source scanning systems, and various optical trapping or optical tweezer configurations. The reason for demand in these applications is the extremely high magnification and control needed to not only visualize the sample or object of interest, but to precisely control and isolate regions of interest in samples such as cells, proteins or individual chromosomes and amino acids. Cooper: Cutting-edge techniques appear to be getting the majority of NIH funding. Scanning systems are crucial in multiphoton microscopy, which increases the depth at which scientists achieve noninvasive images of neurons in their natural environment. High-speed wavelength control is a principal requirement of optogenetics. Vorndran: Applications related to single-molecule research. These are essential in understanding the function of the "nanomachines" inside the cells. PI is working with a number of leading scientists in this field. Zemek: Superresolution microscopy and selective-plane light-sheet microscopy. Researchers need to image life in action, and intracellular processes require high resolution at low light levels. It is very hard to image live cells without damage – this is the trick to master. Hodge: We are constantly looking for tabletop solutions for devices that used to fill a laboratory space. That is what is driving commercial applications using highly stable and precise devices that fit into a small space. Positioning products The companies consulted for this article offer the following: • Applied Scientific Instrumentation: Ultraprecise DC servomotor and piezo stages for microscopy positioning; selective-plane and light-sheet microscopes with piezo- and servomotor control. • Edmund Optics: A number of actuators and motorized stages for biomedical and life sciences applications that require high-precision automation and repeatability. • New Focus: Newport's range of piezo-based nanopositioners includes the Picomotor and Agilis, as these products provide set and hold adjustment and positioning of a few tens of nanometers for optics, specimen adjustment, and laser and fiber alignment for various biophotonic instruments. • PI (Physik Instrumente): Piezo nanopositioning stages, nanofocus devices for microscopy, piezo ultrasonic motors and transducers, precision linear and rotary positioners, and hexapod six-axis positioners. • Siskiyou Corp.: Submicron micromanipulators for electrophysiology and related hardware for attachment to imaging systems; monolithic flexure mounts for positioning optics in applications demanding high stability and precision. • Sutter Instruments: Micromanipulators, including the Quad, a four-axis micromanipulator that extends the range in the X and Z planes and offers drift-free fine control of electrode positioning; microscope translation (motorized and manual); and motorized microscope stages.