text:
How Do You Divvy Up the Dirty Work? (#Giveaway)11:06 PM
Do you find yourself keeping score when it comes to chores in your home? Like most married couples, my husband and I struggle not to get in a situation where we track who does what and assume that we are each doing more than our fair share.
Since we know that things are never 50/50, I was interested to see the findings of a recent study from Scrubbing Bubbles (called the Dirty Work Index™ survey), where they examine the difference between men and women's attitudes towards household chores. Some of the most fascinating facts are being shared via the Scrubby Solutions Facebook tab -- complete with video commentary from John Gray of "Men are from Mars, Women are from Venus" fame.
Here is just one surprising fact from the study:
When it comes to cleaning, women think they do it all. In fact, 58 percent of women say it's their "job" to clean, and a quarter (25 percent) of all women feels as if they are the cleaning "leader" in their homes. Conversely, more than half of women confided that they want more overall help from their partner or spouse, but 38 percent don't trust them to meet their standards of cleanliness.Would you have guessed?
To learn more facts and participate in the discussion, be sure to visit the Scrubby Solutions tab, as well as check out tools for getting it clean via the Scrubbing Bubbles website!
Wanna Win? We are giving one lucky reader an assortment of Scrubbing Bubbles Extend-A-Clean products: Active Scrub, Bathroom Cleaner, and Mega Shower Foamer. To be entered to win, just tell us tell us how you handle the chores in your home! You have until March 10th at 11:59 pm CST to get your entries in, and winners will be randomly selected from all eligible entries. You may enter every day and we will pick one winner at random from all eligible entries. (Please answer the question for the first entry. Each entry after that can be "enter me.") This giveaway is open to U.S. residents ages 18+. See our full rules here.
Don't forget to enter our other blog giveaways while you're here!
110 comments
Me and my parents share the chores. So we get it done faster like that.ReplyDelete
Sweetlikecandy1688 at gmail dot com
- AnonymousMarch 9, 2012 at 7:10 AM
We have a chore chart so everyone helps out.ReplyDelete
Desiree Dunbar
I have an app that helps keep me on track. It similar to Fly Lady and I love it!ReplyDelete
Jennifer W
It's all me, so I just knock them out, usually while my son is nappingReplyDelete
our family shares the chores and everyone pitches in but sometime they need a little pushReplyDelete
- JaniceMarch 9, 2012 at 8:31 AM
enter me (3/9)ReplyDelete
- AnonymousMarch 9, 2012 at 8:42 AM
3/9 entryReplyDelete
~eunice b
tigergal01 @gmail .com
EVERYONE pitches in, there's no way I can do it all myselfReplyDelete
- AnonymousMarch 9, 2012 at 8:49 AM
I am the one who does all the chores. I will sometimes give the kids something to do to help me out though.ReplyDelete
Lona728@ yahoo dot com
I do majority of the chores, but my husband helps out sometimesReplyDelete
xxkimhcxx at gmail dot com
enter me 3-9ReplyDelete
Where did the rest of the comments go?? I've been entering every day.ReplyDelete
- AnonymousMarch 9, 2012 at 9:49 AM
Enter me 3/9ReplyDelete
Everybody pitches in so we can work together to get all of the chores done. Thanks for the awesome giveaway!ReplyDelete
Tandt625 at hotmail dot com
I do 99% of the cleaning around the house, I dont mind :)ReplyDelete
nippytay at gmail dot com
I just do everything!ReplyDelete
If I'm lucky, someone else will take out the garbage or do the dishes.
- AnonymousMarch 9, 2012 at 11:32 AM
I do most of the chores, but my hubby helps. I try to do them in rotations (every two weeks vacuum, every week clean bathrooms, every month baseboards, etc) so I don't feel like I'm cleaning constantlyReplyDelete
- AnonymousMarch 9, 2012 at 11:41 AM
I usually do major chores when everyone is home on Saturday and things like dusting and vaccuming during the week. JDReplyDelete
Most of the chores are still just on my shoulders because my kids are small. I do try to involve them in a few simple tasksReplyDelete
poniabaum at gmail dot com
I do almost everything. What my husband does do I end up doing it again.ReplyDelete
my husband THINKS he is helping but only makes my work harderReplyDelete
- AnonymousMarch 9, 2012 at 12:58 PM
enter me!!!!!!!!ReplyDelete
I do a quick pick up & sweep daily in the house & do the big clean on the weekends when the kids go to their dadsReplyDelete
For the most part I do all the chores. My lil girl has a few chores and she really enjoys doing her laundry!ReplyDelete
mhcommet (at) yahoo (dot) com
I do most of the houseworkReplyDelete
jofo120 at yahoo dot com
I do everything except the vacuuming and taking out the trash. The worst part? Doing dishes!!! I'd clean my bathroom all day to avoid doing a load of dishes!ReplyDelete
Maggie Armstrong
Enter me.ReplyDelete
janetfaye (at) gmail (dot) com
I do most of the chores and my family helps me on the weekend.ReplyDelete
janetfaye (at) gmail (dot) com
I have a list, and I do it!ReplyDelete
Melanie MOntgomery
My kids have a chore chart and do well on it. I know that I'm most productive in the mornings so I try to push and get as much done in the morning as I can. It still feels like our house is always messy.ReplyDelete
firstname.lastname@example.com All three of us keep working till the chores are all done. So we spend the same amount of time doing chores even if the number of chores each one does is different.ReplyDelete
I do the heavy cleaning once a week (usually sunday) and then do light cleanine once a dayReplyDelete
mellanhead74 at hotmail.com
On the weekends I try do catch up with laundry and any other chores that need to be done. During the week, my husband keeps up with the minor housework like dishes and cooking.ReplyDelete
We handle the chores in our house by dividing up the chores. Hubby does the floors and dusts. I clean bathrooms & laundry.ReplyDelete
- AnonymousMarch 9, 2012 at 11:39 PM
I 'like' you on facebook as Constance VannReplyDelete
- AnonymousMarch 9, 2012 at 11:40 PM
I shared this giveaway on facebook as Constance Vann.ReplyDelete
- AnonymousMarch 9, 2012 at 11:45 PM
I hate doing house work, but it has to be done so I do it. The one thing I hate the most is cleaning the bathroom. That is the pits, but again it has to be done so I do it. I thought that if I could win this Scrubbing Bubbles prizes it would help me feel a little better about myself as I clean the toilet. Ack!ReplyDelete
- AnonymousMarch 9, 2012 at 11:46 PM
Enter me please! Thank you!ReplyDelete
- AnonymousMarch 9, 2012 at 11:49 PM
Enter me please! Thank you for offering us the chance to win!ReplyDelete
As a single dad, I pretty much do it all myself! (Corey Olomon)(firstname.lastname@example.com)ReplyDelete
We buy our cleaning products in bulk. My wife and I divide the projects in half.ReplyDelete
sweepsking35 at yahoodotcom
I do everything myselfReplyDelete
bmweida at yahoo dot com
- Ashley T.March 10, 2012 at 4:05 AM
I do it myselfReplyDelete
ajoy1332 at yahoo dot com
I let my sweetie do it. Email: yona(at)pricelesswriters.comReplyDelete
Enter meReplyDelete
Sweetlikecandy1688 at gmail dot com
I live alone, so I do all the chores. Thanks for the giveaway.ReplyDelete
I have 3 kids and myself to do the chores....and sometimes (usually) it's just me...and I do them all in one sweep on on day.ReplyDelete
I have no choice but to do ALL the chores myself, includint the yard work. HOwever the yard work I enjoy so I don't think of it as a chore. I do have the kids that have to maintain their rooms but the remainder of the house is ALL mine! I am now starting the Spring Cleaning so this would really come in handy!ReplyDelete
Thanks for the opp!
We have a chore chart that changes every week, so everyone helps out with a little something.ReplyDelete
marija.majerle at gmail dot com
enter meReplyDelete
slrdowney at hotmail dot com
enter me (3/10)ReplyDelete
i just attack the house cleaning on full force every sunday and just do everything, and let it get messy all week hahaReplyDelete
daniellex at gmail dot com
I try to do a room a dayReplyDelete
daily entryReplyDelete
I do all the cleaning myself.ReplyDelete
spcale at yahoo dot com
- AnonymousMarch 10, 2012 at 9:11 AM
Enter me 3/10ReplyDelete
We have a chore chart in my house... But I am usually the one who ends up doing everything ♥ The joys of motherhood ♥ReplyDelete
Thanks for the chance
enter me 3-10ReplyDelete
I do most of it but there are a few things we divide amongst the kidsReplyDelete
enter me 3/10ReplyDelete
I just take a deep breath and get it done.ReplyDelete
bethelderton59 at gmail dot com
We write the chores on small slips of paper. The kids draw one out each day and that is the chore that they do! firstname.lastname@example.com
We all share the cleaning but some things do go to one person: Mom likes to dust, Dad does laundry, Mom doesnt mind ironing, Dad cleans the kitchen, everyone pitches in on bathrooms, vacuuming, etc. This prize package would help keep us clean :) Stephanie email: email@example.com
- AnonymousMarch 10, 2012 at 11:26 AM
The way I "handle" bathroom chores has changed since my newly-married days.ReplyDelete
In the early days of my marriage, my approach was to not clean it, and see how long it took my hubby to feel like he must...that didn't work. My resolve wore thin as the mildew accumulated on the bathtub, and the ring around the toilet made me gag...
Now, after 15 years, I realize that I must clean the bathroom, but in exchange, I get a man who will do the dishes, cook great dinners part of the time, and clean up the living room. He is a good man, and pretty-satisfactorily house trained, as far as men go...
I do the cleaning myself and I have certain days that I do certain choresReplyDelete
I handle the cleaning and chores in my house mainly bymyself! I try to keep up on everything by cleaning, picking up, and putting things away when ever I can. At least once a week I fully attack my home and do a deep scrubbing of all bathrooms, showers, kitchen, floors, and windows! Some days I slack though and things can get dirty and at that point I really who somebody else pitches in a bit!ReplyDelete
lovetogive123 at gmail dot com
Please enter me 3/10ReplyDelete
jackievillano at gmail dot com
- Iliana ReyesMarch 10, 2012 at 2:12 PM
My mom does the cooking, my dad the laundry, and me everything else!ReplyDelete
We split up the cleaning, though my mom likes to do most of the work. email@example.com
I live alone so I try not to be too messy and do everything myself!ReplyDelete
enter meReplyDelete
I try (and I stress TRY) to keep a routine. Space out the chores throughout the week so I can get stuff done in a regular fashion without getting overwhelmed. All the laundry done and put away in one day, vacuum/mop floors/clean bathroom another day, etc. I try. LOL.ReplyDelete
wowknk at gmail dot com
We have "The Blitz" - 15 minutes of rapid cleaning of a common room by the whole family, while music is played. Other than that the chores are fairly haphazard, unfortunately.ReplyDelete
my husband the kids and me split the choresReplyDelete
-We shares the choresReplyDelete
Email: starseeds88 (at) yahoo dot com
Enter Me (THANKS!)ReplyDelete
I'm the primary person cleaning in my home but my children have their own chores they must complete daily.ReplyDelete
lisalmg25 at gmail dot com
I do most myself during the week. My fiance sweeps and dusts on weekends.ReplyDelete
thisisme79 @ gmail dot com
My husband and I share the chores.ReplyDelete
I have the kids help, but I do most all of the chores.ReplyDelete
- barb huntMarch 10, 2012 at 5:10 PM
Thanks for the great contest!ReplyDelete
enter me!ReplyDelete
- AnonymousMarch 10, 2012 at 6:37 PM
we divide the chores and rotate the chores, email@example.com
My daughter & I split the chores as my husband works long hours.ReplyDelete
- AnonymousMarch 10, 2012 at 7:26 PM
Everyone pitches in to get the chores done wilcarvicReplyDelete
I clean one room a day!ReplyDelete
My boys are saving up for a very expensive toy, so I pawn as much as I can on them. Thank youReplyDelete
Everybody gets a turn from cooking to cleaning.ReplyDelete
Theresa N
I give them to my husband to do :-PReplyDelete
tamarsweeps at gmail [dot.com
my husband and I split the choresReplyDelete
dlatany at gmail dot com
Our whole family works together to clean the house!ReplyDelete
- AnonymousMarch 10, 2012 at 8:36 PM
I handle chores by doing them a room at a time. For instance, one day I will focus on the kitchen and the next day I will focus on the bathroom. It keeps me from being overwhelmed.ReplyDelete
I do almost all of the cleaning and my husband does the dishes. It's the only chore I can't stand.ReplyDelete
cochina1414 at yahoo dot com
I clean everything by myself.ReplyDelete
ccboobooy at gmail dot com
I take care of all of the cleaning, not because I have to, but because I love my family and want them to have a clean home!ReplyDelete
I'm the only one in my house so I try to do a little bit every day.ReplyDelete
My husband and I share the chores so it doesn't get too overwhelming.ReplyDelete
I do most of the chores. Sometimes I give my husband the outsde chores but he has a bad habit of mowing my plants or pulling what he considers to be weeds but are really flowersReplyDelete
alliana88m AT yahoo DOT com
I do just about everything myself! Even when someone esle do anything..I go behind them because I am a perfectionist!ReplyDelete
Thanks for the giveaway...we try to "clean as we go", keeping the house clean by breaking down the jobs into discrete parts that we do each day i.e. vacuuming every other day, etc.ReplyDelete
senorpiero [at] yahoo [dot] com
I do mostly everything myself but break it up to make it easy on myself.ReplyDelete
I usually do the chores during the weekend, splitting them up into 2 days. Sometimes I just do the laundry throughout the week though. My husband helps out with the vacuuming and picking up things and usually does most of the cooking and unloads the dishwasher for me.ReplyDelete
davandihamilton (at) gmail (dot) com
I divvy them up between ME, MYSELF AND I.ReplyDelete
Thanks for the contest.
Weeeeeeeeeell its me. My husband "helps." email@example.com
I do them and do a lot daily.ReplyDelete
enter me (last day)ReplyDelete
"enter me."ReplyDelete


text:
What are my gifts? What is my potential?
If you have ever asked yourself any of these questions, then you have come to the right place.
The core of the Academy's program are the Meditation Retreats. They provide a space to go in, to move away from the hectic pace of life and to remember yourself. It is a journey of coming home through self inquiry. Most of us long to find inner peace and a joyful connection with ourselves, others and life.
You start with an Awareness Intensive (Satori, Who is in?) or a Meditation Retreat (Zazen, Kyol Che, Vipassana) and continue with one of the Creative Expression programs (Clowning, Calligraphy, Sculpting, Gurdijeff Movements).
The intention of this follow-up program is to anchor the inner expansion, experienced during the retreat, into daily life. The seminars leave enough space for beaching, walking, resting, hanging out and meditating.
14 Days Satori
9-23 October 2021
with Ganga & Avikal

subset: commoncrawl


text:
How did you like going up against Soloman Alabi of Florida State?
Yeah. I really enjoy playing against guys my size.
What did you learn from the Belmont game last season?
Actually, Belmont was a good team and they played really well, but for us, it was definitely a lesson not to look forward to the next game. Everybody is hungry and a champion out there for the most part. I know Binghamton is, so they know how to win. It'll be a good game.
Has the team learned anything from going out within the first two games the last two times out?
If we haven't learned from the last two years, then it's pretty stupid of us. It's different this year obviously. Look what we have accomplished so far and we're not done and are ready to move on. We're definitely more confident this year. It's a lot harder when you come off two losses to North Carolina and Clemson. This year it is a completely different story. I think we are just happy to be playing. There is not much of a difference in what we do each day. But, I think we are in a better place mentally and physically. We're not as worn down as we were and are ready to go.
What kind of role do you see yourself playing in the tournament?
I think I can play a key role. It's a little bit harder for me to play against some of the smaller teams, like Maryland where there center goes out and shoots threes a bunch. I mean going in against Florida State - it was a huge role for me. And if we advance, there are Texas and Pitt ... there is a lot of good teams out there with big guys.
Can you talk about Lance Thomas and his contributions?
His play has been huge. He is literally our best defensive stopper from position one to five. That's a huge key for us. It allows for us to be really strong when we switch off and not have any downside.
In Atlanta, there were lots of Carolina fans cheering against you and Greensboro could be much the same, does that bother you?
I think it's tough. There are so many Carolina fans around here. But I think that we feed off of that and we like it. We play like environments like that a lot and we hear it, whether it is during the day or outside of basketball. We are just looking forward to taking care of business and that's how we are going to make our statement. It's nice not to have to wait on a plane to get ready because it takes a toll on you. Just to be able to go on the bus spend some time with the team and get ready to play. So, being close is huge.
Concerning Coach K's adjustments and playing close games -
I think it's been really important in that a couple of the games we had against BC and Maryland. We might have lost them last year and having that experience and not panicking when they hit a few shots or come back and make it close. We were down against BC but came back and we were ready to move on and move past them. So, that shows some maturity.
Is the team looser going into the NCAA's?
The team is not as uptight. Like, I said against BC it's easy to panic and worry about your shots or every little thing that goes on and it can effect your game. What we do is try to concentrate on what we know we can do well and that's play defense and rebound and if we do that the offense is going to come around.


text: I am a doctor by profession , but there has always been a longing to be in nature , to feel the gentle breeze , to open my eyes to the clearest blue sky , to smell the crisp fresh air of spring , to hear the crisp , melodies of birds ...aah I can just sit through such feeling whole day . As I could not afford such leisure due to time constraints , I paint what I wish to see and experience , my love for nature is what inspires me to click , draw , paint . It makes me feel so close to nature..... I hope you experience it too through my paintings/ photographs.


text:
Sleepy Offense
Let's see, the season has passed the six-week mark.
After 40 games, the Phillies are 25-15, the best in the NL and the exact same record as a year ago when they the majors in wins. That's encouraging, discouraging and somewhat surprising.
Encouraging in that this team hasn't had Chase or Brad for one game with a bushel basket of others on the DL or sidelined with injuries, Shane being the most recent.
Discouraging because of the offense. For the first time this season, the Phillies have lost three in a row. Monday night they had five hits, which follows four and three in the other losses. Folks, that's 12 hits in three games. They are now 7-7 in May, scoring 37 runs in the wins and 10 in the losses.
Somewhat surprising. The five-man starting rotation was supposed to carry this team and for the most part, it has. Yet, Roy-O and Joe have missed time because of injuries. Doc hasn't won since May 5 and Lee's last win is April 14. Lee walked seven all season until Monday night when he walked a career high (227 starts). Lately, the best pitching has come from three rookies, Antonio, Michael and Vance and Vance is back in AAA.
During this 20-game stretch against teams that are postseason candidates, the Phillies have been seeing some good pitching. Tuesday night, lefty Garcia, St. Louis' best hurler faces the Phillies slumbering offense. Roy-O is facing major league hitters for the first time since April 21.
Wednesday's game against the Rockies at Citizens Bank Park is an ESPN telecast . . . Lee's next start will be against the team that went to the World Series with him as an ace, yes, the Texas Rangers, who open a weekend series on Friday night. Lee will pitch on Saturday, a 7:10 prime-time FOX national telecast . . . Phillies are 17-2 when scoring four or more runs.
Down On The Farm
RHR David Herndon recorded his first AAA save as Lehigh Valley won, 4-2, over Norfolk . . . Reading was not scheduled . . . Clearwater fell, 3-1, on only 5 hits in Bradenton . . . DH Anthony Hewitt and RF Zach Collier had 3 hits each in a Lakewood 8-3, 12-inning loss to Hagerstown.
On This Date
1979 – The wind is really blowing out at Wrigley as the Cubs and Phillies join in a wild ten-inning slugfest won 23-22 by the Phillies Dave Kingman has three home runs and six RBI for the Cubs while teammate Bill Buckner, a grand slam and seven RBI. Mike Schmidt two home runs include the game-winner in the tenth inning. The eleven home runs between the two teams ties a major league record.


text:
Table of Contents
Research and general acceptance
Optifast is an all liquid diet. It is intended for significant weight loss in a short period of time, is intended only for the extremely obese, and must be completed under the supervision of a trained physician.
Optifast is a line of products and an associated diet plan produced by the Novartis Medical Nutrition Corporation. The company is headquartered in Basel, Switzerland and produces many different pharmaceutical and general nutrition products including Gerber baby food. According to Novartis, since the company introduced Optifast in 1974, more than one million people have used the diet. It was the first all liquid very-low calorie physician monitored diet to be available commercially. Although the Optifast line began with pre-made drinks, it has grown to include soup mixes and nutrition bars. The company has also branched out to produce products and associated diet
(Illustration by GGS Information Services/Thomson Gale.)
plans intended for adolescent patients and patients undergoing gastric bypass surgery.
The Optifast diet generally consists of four phases: screening, active weight loss, transition, and maintenance. Novartis provides training for physicians and other healthcare professionals who are going to be involved in monitoring and providing support to patients on the Optifast diet. Novartis provides general guidelines for administering the diet, but each clinic or physician may offer whatever specific program they chose. Therefore, no two experiences with Optifast will necessarily be the same. The following is a general overview of what many clinics offer.
The first phase of the Optifast diet is screening. Optifast is only appropriate for massively obese people, generally those who have at least 50 pounds to lose or are experiencing obesity-related complications. In most cases the diet is only recommended for patients between the ages of 20 and 50. The physician will do a general health screening and various lab tests to determine if Optifast is likely to pose any special risks to the patient. During this time the patient may be able to meet the various support staff that he or she will be working with while on the diet, including the physician, nurses, lab technicians, psychologists, counselors, nutritionists, and anyone else who is going to be on the medical team.
After screening has been completed and it has been determined that the patient is a good match for the Optifast diet, the diet itself begins. This is the active weight loss phase and generally lasts from 4 to 6 weeks. During this phase the patient is on a fluid-only diet using Optifast products. These are nutritional drinks that come in a variety of flavors, and generally provide a total of fewer than 800 calories per day. This means that the Optifast diet is considered a very-low calorie diet (a diet providing fewer than 800 calories a day). Generally 5 Optifast drinks are consumed throughout the course of a day, and doing so provides the recommended daily allowance of vitamins, nutrients, proteins, and other substances necessary for good health.
During the active weight loss phase the patient meets with a physician once or more weekly to monitor progress and health. Lab tests may be repeated to check various levels such as cholesterol or blood glucose. As weight loss increases medication dosages may be altered, and the amount of Optifast consumed each day may be altered to fit changing caloric needs. Also during this time the patient will meet, usually in a group, with a trained psychologist or therapist to discuss any problems or obstacles he or she is facing. During these group meetings patients will begin to learn new behaviors and eating patterns to help them maintain their weight when they begin eating self-prepared foods again.
After the active weight loss phase is finished the transition phase begins. During this time the patient begins to replace the Optifast drinks with solid foods. Patients work with a nutritionist to help them learn to choose meals high in fruits, vegetables, and whole grains and low in fats and simple carbohydrates. During this period the patient continues to meet with the physician regularly and attend group classes. This phase usually lasts 4 to 6 weeks.
Once the transition to solid foods is complete the maintenance phase begins. During this phase the patient begins to practice the good eating and healthy living habits learned during the program. Exercise is emphasized as a way to help prevent the re-gaining of weight lost. Many clinics offer classes and meetings that patients can attend to help them as they try to keep the weight off.
Although the very-low calorie diet was the original Optifast product, the line has begun to branch out and now offers a variety of diets. One diet is used for patients who are going to undergo bariatric surgery, and can be administered both before and after the
surgery. This can help reduce complications and smooth the transition into a fluid-only diet after the surgery. Another diet is an Optifast diet intended for very obese adolescents. Optifast also offers bars and other products, which are not associated with its original fluid-only diet. In addition to the very-low calorie diet, diet plans with a more moderate quantity of calories per day are also available.
The Optifast diet is intended for significant weight loss by the extremely overweight. It is especially aimed at those people who have health problems related to obesity and who need to lose significant weight quickly to avoid serious health complications. The Optifast diet must be administered by a physician who is trained in using the Optifast system. Although the eligibility requirements for the Optifast program vary from clinic to clinic, generally a person must be at least 50 pounds overweight to be eligible for the Optifast diet. It is not intended for people interested in losing 10 or 20 pounds that are more a cosmetic problem than a serious medical issue.
There are many possible benefits to significant weight loss for the obese. These benefits can include both looking and feeling better, as well as having more energy. In addition to these general benefits there are many specific health benefits to weight-loss. These benefits tend to be even greater for people who are moderately or severely obese because a greater degree of obesity is generally associated with greater health risks.
Novartis Medical Nutrition, the makers of Optifast, reports that in 20,000 people studied who had completed 22 weeks of the Optifast diet, on average there was a weight loss of 52 pounds. This was a loss of 22% of body weight. They also report an average decrease of 29% in blood glucose levels, a 15% average decrease in total cholesterol, and an average decrease in blood pressure of 10%. Reductions in cholesterol and blood pressure can be especially significant in overall health gains from weight loss because they are important risk factors for heart disease.
Another possible benefit of the Optifast diet is an opportunity for the dieter to re-learn food habits and behaviors while on the all-liquid phase of the diet. During this time no food choices have to be made, the program is firmly outlined. Therefore it may provide an opportunity for the dieter to take a more objective look at some negative eating habits, and come up with positive ways of dealing with potential problems, before going back to eating self-prepared foods.
Some people also believe that Optifast may provide psychological benefits to dieters who have very significant amounts of weight to lose. It can be frustrating to lose one to two pounds a week if the eventual goal is weight loss of 100 pounds or more. A program like Optifast that allows a large quantity of weight loss in a short period of time may allow dieters to be encouraged by seeing results more quickly, possibly providing positive psychological benefits.
There are possible risks for any diet, but the risks associated with a very-low calorie diet can be more serious. Optifast is designed to be a complete replacement for all meals, so it contains the daily recommended amounts of vitamins and minerals. However, because these recommendations are made for the average, healthy adult, they are not necessarily right for everyone. Because severe obesity has many common complications, daily requirements of vitamins and nutrients should be considered carefully for each person thinking of beginning the Optifast diet.
Another risk of following a very-low calorie diet is an increased risk of gallstone formation. Gallstones are more likely to occur in women than men, and are more likely to occur during rapid weight loss or when following a very-low calorie diet such as Optifast. Other side effects of a very-low calorie diet can include nausea, fatigue, constipation, or diarrhea. In most cases these problems resolve in a few weeks and are not very severe.
Whenever a person loses a very large amount of weight in a very short time there are certain risks. Many medication dosages are prescribed based on a person's weight. Therefore what might be the right amount of medication when beginning the Optifast diet may be too much only a few weeks later when weight has been lost. In some cases this may cause an overdose. This is one of many reasons that it is critical to be under medical supervision during the Optifast diet, so medications can be adjusted appropriately as weight is lost.
Research and general acceptance
Optifast has been used in many studies investigating the impact of very-low calorie diets. It has not been studied intensely in relation to other similar very-low calorie diets. It has been shown to have many positive outcomes, such as lowered cholesterol levels and reduced risks of cardiovascular disease. It has also been shown that in patients who are going to undergo laparoscopic adjustable gastric banding (a procedure in which a band is placed around the upper part of the stomach causing patients to feel full with less food) following the Optifast diet for 6 weeks prior to the procedure can reduce liver size and fat content, allowing
surgeons better access and reducing the possibility of complications.
Although there are many documented benefits to the Optifast diet, there are some people who suggest there may be other, more beneficial diets with fewer possible negative side effects. It has been shown that very-low calorie diets such as Optifast are not any more effective at keeping weight off in the long run than more traditional diets. This suggests that for some people the risks and benefits of a very-low calorie diet should be assessed in regard to the long term effects, and not just the speed of original weight loss. Another reason that some people may prefer more traditional diets is that the Optifast diet can be prohibitively expensive. The diet can cost upwards of $2,000, depending on the clinic at which it is administered and how long the active weight loss and transition phases last.
Shannon, Joyce Brennfleck ed. Diet and Nutrition Source-book. Detroit, MI: Omnigraphics, 2006.
Willis, Alicia P. ed. Diet Therapy Research Trends. New York: Nova Science, 2007.
Kanders, BS, et al. ''Weight Loss Outcome and Health Benefits Associated with the Optifast Program in the Treatment of Obesity.'' International Journal of Obesity (1989)13, Supplement 2: 131-4.
Agras, W. Stewart, et al. ''Maintenance Following a Very-Low-Calorie Diet.'' Journal of Consulting and Clinical Psychology (June 1997) 64,3: 610-613.
American Dietetic Association. 120 South Riverside Plaza, Suite 2000, Chicago, Illinois 60606-6995. Telephone: (800) 877-1600. Website: <http://www.eatright.org>
Novartis Medical Nutrition, US. 445 State Street, Fremont, MI 49412. Telephone: (800) 333-3785. Website: <http://www.novartisnutrition.com>
Optifast.com 2007. <http://www.optifast.com> (March 26, 2007).
Optifast. Videotape. 1984.
Helen Davidson


text:
It's almost the end of August, and for one reason or another, you haven't gotten your summer break in yet. And maybe you think it's too late, that all the hotels, motels and resorts have long ago posted their "No Vacancies" signs. But you would be wrong. With a bit of effort (say, a couple of hours) you can book yourself a summer vacay for 2012 and nobody will be the wiser that you waited until the week before to plan it out.
Be flexible about your destination: At this point, you may want to choose at least three potential vacation spots so you can be flexible about which one has the best deals and most room or is easiest to organize. You also might want to consider a destination within, say, a six-hour drive of your home. That way, you don't have to worry about oversold flights and the expense of airport transfers or a rental car at your destination, all of which can be very pricey last-minute.
Road-trip it: Consider going to a sister city, or seek out a lake- or ocean-front town that is far enough away to be a vacation, but not so far away that getting there is too big of a deal. I like five or six hours, because it feels far away, takes about a tank of gas, and if you get on the road by 7 a.m., you can be at your destination by lunchtime and have the afternoon to get settled in.
Call chambers of commerce: This is the single best way to find out if there are vacancies still available in more busy locales, like Martha's Vineyard, the Hamptons, the coast of Maine, the Outer Banks of North Carolina, mountain towns in Colorado, and coastal locales on the West Coast. (No disrespect to the Midwest, but these are the places I have actually been.) How it usually works is that the chambers keep pretty close tabs on hotel, motel and B&B vacancies, and also know the lodgings well. So you can call (no, you can't do this online!) the local chamber of wherever you happen to want to visit, and tell them the exact dates you'd like to stay, your price range and what you are looking for (near town, waterfront only, etc.) and they can tell you what's available. This is where it pays to be flexible, as you may not be able to afford, or get into the famous oceanfront B&B, but there might be good availability elsewhere. And who knows what new gem or experience you might encounter going off your own beaten path?
Search online for last-minute deals: Simply enter the name of the destination you are considering, and the term "last minute deals" and see what comes up. I did this for Nantucket and found several B&B's offering some pretty sweet discounts (including second night half-off or third night free, and a cut price on ferry tickets if you buy them through the lodging), and availability for next week. Consider cruises and the Caribbean, and suddenly, there's more last-minute deals than you can handle.
Good luck! Don't miss out on your summer vacation. You deserve it — and you probably need it.


text:
In accordance with Governor Wolf's mandates for Montgomery County, the Elkins Park campus and all clinics are closed until further notice. For up-to-date information, please continue to check this website.
CPPD intends to use virtual communication to maintain the structure of their current schedule.
Salus University faculty are widely recognized scholars whose presentations, articles and scientific papers are published in the leading outlets of their disciplines. Passionate about their research, they are equally dedicated to teaching.
Adjunct, CER, Occupational Therapy
Associate Professor, College of Education and Rehabilitation
Assistant Professor, CER, Occupational Therapy
Adjunct, CER, Blindness and Low Vision


text:
Emily Badger
Emily Badger is a former staff writer at CityLab. Her work has previously appeared in Pacific Standard, GOOD, The Christian Science Monitor, and The New York Times. She lives in the Washington, D.C. area.
Dowell Baker, a law firm specializing in patent litigation in Lafayette, Indiana, finds companies to target in a couple different ways. The firm's client, ArrivalStar, holds 34 U.S. patents, all related to the idea of tracking a vehicle in motion and then alerting people, through some communications device, of when it may arrive or whether it's running late. As you might imagine, many entities – airlines, school buses, freight-tracking services, package-delivery companies – do something quite similar to this. And Dowell Baker believes they're all infringing on these patents.
The firm scours for potential infringers on the Internet. Sometimes, companies that have already been sued by ArrivalStar – and now license its patents – will tip off the firm to its competitors. And then there are the really easy targets: public transit agencies. They're quite public about the cell phone apps and notifications that you can sign up for, as a rider, to keep tabs on buses and trains. And so Dowell Baker signs up for them, too.
"We had to get a separate phone account," says partner Anthony Dowell, "because no one wanted to get all these notifications on their phone."
This is a strange story. And this detail probably conveys that best: There is a dedicated cell phone sitting in a law office in Indiana pinging at all hours of the day with alerts about bus delays and approaching trains in cities across the country.
The case is particularly odd given that ArrivalStar sells no product or service. It isn't really competing with any of these companies, certainly not the transit agencies. When the Greater Cleveland Regional Transit Authority texts its riders about a waylaid train, that service doesn't cut into ArrivalStar's profits. But the company, while it makes little else, controls these patents.
Some of them date back to the mid-1990s, when an inventor named Martin Kelly Jones initially filed them. Today, a company called Melvino Technologies Limited, which is registered in the British Virgin Islands, owns all of his patents. And ArrivalStar, registered in Luxembourg, has the exclusive rights to license them.
Together, Melvino and ArrivalStar have sued at least 10 public transit agencies and threatened legal action against at least eight others. Noticing the pattern, tech and transit advocates have begun to flag ArrivalStar as a "patent troll," a company that exists solely to sue supposed patent infringers for financial gain. Most perplexing to the many people involved is this question: How does anyone own the rights to the obvious idea of alerting people when their train, or bus, or plane might pull in?
"It's a very old conflict in the U.S. patent system," Dowell says. "The Wright brothers never manufactured an airplane, but they filed for and obtained the first patent and engaged in litigation for years about it."
ArrivalStar's critics frame this a little differently.
"It's kind of like a hostage situation," says Julie Samuels, a staff attorney with the Electronic Frontier Foundation. "Because settling it is always going to be cheaper than litigating. When you start suing cash-strapped local governments, they don't have the resources to fight back."
Fighting a suit like this can run into the millions of dollars. So far, every transit agency ArrivalStar has sued has settled, as have more than a hundred private companies. No one has ever taken one of these cases all the way to trial, where a judge might begin to sort out exactly what the broad language in these patents truly means.
"It's a mess," Samuels says. "Not to sound glib, but you're talking about taxpayer dollars when these cities have no money to start with. And that's not what we want our cities focused on now – or ever. But right now, it seems especially egregious."
• • • • •
The Georgetown Climate Center backed into all of this unintentionally. It facilitates the Transportation and Climate Initiative, which brings together officials from 11 Northeastern and Mid-Atlantic states, as well as the District of Columbia, to collaborate on reducing greenhouse gas emissions, creating green jobs and improving transit. These lawsuits caught the center's attention in a roundabout way: Transit apps can help increase or maintain ridership, which helps reduce automobile traffic, which is a major source of emissions.
Several of the partnering agencies, though, brought up fears in developing such apps due to the legal threats from ArrivalStar.
"What they would do is pick off some transit agencies, sue, get a recovery," says Vicki Arroyo, the executive director of the Climate Center. "They might sue for six figures, settle for five figures, and go on to the next one. As a result, nobody was really stepping back and seeing how big the picture was."
As Arroyo sees it, this is ArrivalStar's whole business plan. All of its revenue derives from suing private companies and public agencies to license an idea they were surely capable of coming up with on their own. About 65 percent of the national transit fleet now contains "automatic vehicle location" technology, most of it paid for by the federal government. These systems now enable transit agencies to track in real time most of their buses and trains. And as a logical next step, over the past few years they have begun turning over this tracking data to developers to create free user applications.
Arroyo and Samuels suspect a concerted conquer-and-divide campaign on the part of ArrivalStar. It never sues too many agencies at one time, preventing them from realizing their common cause. And it always asks for a licensing fee that's just big enough to hurt, but small in comparison to the cost of litigation. (Dowell counters: "I think they may be giving us more credit than we deserve.")
The Climate Center and EFF have now taken up the task of trying to coordinate some solution. Georgetown has compiled a file of all the relevant patents and known lawsuits, as well as potential legal defenses that might be used to counter them. EFF is leading the hunt for "prior art" that might be used to invalidate some of the patents, proving that Martin Kelly Jones' ideas were around before he had them. The American Public Transportation Association is also now following the suits, as is the federally funded Center for Urban Transportation Research at the University of South Florida.
James P. LaRusch, APTA's chief counsel, said in a statement that these suits against its members "continue to be a financial and administrative burden for those agencies, diverting precious resources from the important business of providing service to the riding public." APTA is now also working with the U.S. Department of Transportation on the problem.
"It's a rabbit hole that just keeps getting deeper," says Sean Barbeau, one of the researchers at USF.
Barbeau has developed some of these prototype apps, including one that helps riders with intellectual disabilities navigate public transit. That's one of a wide range of publicly beneficial tech tools that could be at risk here.
"One of my concerns is that there has been a lot of progress in terms of convincing agencies that it's in their own best interest to share their information," Barbeau says. "That was an incredibly long process, and there's been a lot of progress there."
Public agencies release their data in part because app developers can give that data value.
"These aren't huge companies rolling out mobile apps. They're individuals, or very small businesses," Barbeau says. "If those businesses or individuals are served with cease-and-desist letters, or they have to purchase licenses, it's most likely they're just going to fold up shop and go home."
If that happens, Barbeau worries, public agencies may no longer have a reason to release their data at all. And that's a threat to innovation at its core, as well as to the open-data, open-source movement, in which all of these tools are publicly shared, not proprietary. Already, Barbeau and others say they've begun to witness a chilling effect from the ArrivalStar suits. People are afraid to develop ideas. New apps aren't coming out. It's impossible to quantify the effect, though; you can't count things that haven't been made.
• • • • •
Dowell blames tech startups and app developers for "raging forward" without researching what has come before them.
"In our view," he says, "Martin Kelly Jones did invent the technology, he did spend the time and money to patent it, and we just believe that anyone that's using it, any company that is deriving a profit from the use of it in one way or another – even if they don't charge for the service – we feel that they need to compensate the inventor for the invention."
Dowell says that Jones is still involved with both ArrivalStar and Melvino, although he no longer personally holds the patents. Asked where he lives and whether he's an American, Dowell demurs: "He doesn't like me to talk about that."
Jones' 34 patents cover a variety of riffs off his main idea: alerting someone when a vehicle is delayed, alerting someone when it's within a certain arrival time, alerting someone when it's within a physical distance from a given spot. His initial idea was to create a system that would alert families to an approaching school bus. Dowell says the company was ultimately unsuccessful in getting any such service off the ground. And so ArrivalStar evolved by the late 1990s into a company with only patents, but no products. Jones continued to file new ideas. The most recent patent that is commonly cited in the suits against public transit agencies was issued in 2006.
ArrivalStar has been licensing these patents to private companies for about a decade. Its focus on transit agencies has come mostly in just the last two years. It's sued the Massachusetts Bay Transportation Authority, the New York Metropolitan Transport Authority, Chicago's Metra, the Port Authority of New York and New Jersey, and Seattle's King County Metro Transit. Since February of this year, it has also sued transit systems in Cleveland, Monterey, California, and Portland, Oregon.
Dowell argues that ArrivalStar can't distinguish between private companies and taxpayer-funded public transit entities, since many of them contract private firms to run their alert systems. "It's kind of an equitable argument," he adds. If one city has to pay ArrivalStar a licensing fee, is it really fair if other cities don't?
It's unlikely that the public agencies view the problem this way, especially now that they're talking amongst themselves. The agencies that have already settled are barred from publicly discussing the cases due to non-disclosure agreements, as several told The Atlantic Cities. But court records suggest that many of them tried to fight ArrivalStar before ultimately settling (a strategy that undoubtedly reduced some of those settlement amounts).
Lawyers for the Massachusetts Bay Transit Authority referred to the suit as a "shakedown" in moving to dismiss it. King County initially requested that the court invalidate all of ArrivalStar's patents. And the Maryland Transit Administration tried to argue, as an arm of the state, that it had immunity from such suits under the Constitution.
• • • • •
The irony here is that each of these agencies wind up settling for maybe $100,000 to avoid million-dollar litigation, while collectively they will spend much more than that.
"This is a hard problem," says Daniel Ravicher, the executive director of the Public Patent Foundation. He has provided counsel to one of these sued transit authorities (which one, he couldn't say). "Unless and until somebody's willing to stand up and commit significant resources upon which everyone else will be able to free-ride, ArrivalStar will be able to continue to exploit the situation to get trivial settlements from a large number of parties."
ArrivalStar may have just bumped up against one such opponent. Over the winter, it sued the U.S. Postal Service. (Asked whether the Postal Service was infringing by tracking its trucks, or by tracking mail that happens to ride on trucks, Dowell said, "We send out a lot of letters, and I just get them confused about what exactly each company we contact is doing at any moment.")
The Postal Service has given no indication that it intends to settle, and Arroyo is hopeful that that case has now gotten the federal government's attention. Ravicher suggests that there are a number of legal arguments that could be used against ArrivalStar. Its claims are overly broad (as Ravicher puts it: "you transit authority, me patent holder, you infringe,"). Government agencies have immunity from lawsuits in federal court under the 11th Amendment. And then there's the argument that all these patents should never have been granted in the first place.
Other people must have had these ideas before Jones did. The U.S. Patent and Trademark Office, Ravicher says, merely rubberstamps patent applications. The hard work of really investigating them gets farmed out to the legal system. Dowell contends that that these patents are clearly valid because no one has been willing yet to meet ArrivalStar in court. But Ravicher flips this logic.
"If they were being candid, they would tell you 'yeah, we know our patents are pretty much bogus,'" he says. "If they had really invented a cure for AIDS, why would they be settling for such trivial amounts of money? They know their patents are not worth very much, and that's why they're settling for not very much."
Inherent in all of this is a much bigger problem with the patent system, a system that translates particularly poorly to modern software.
"ArrivalStar isn't to blame for this," Ravicher says. "ArrivalStar did not create a system of poor patent quality. ArrivalStar did not create a system that requires millions of dollars to be spent before someone knows exactly what a patent covers or not. ArrivalStar did not create a system that allows people to make flimsy claims for trivial amounts of money."
ArrivalStar is just taking advantage of that system, he says. And then he offers this analogy: If a cockroach comes into your kitchen, that's not really the cockroach's fault. It's yours for leaving out the crumbs.
Top image by Flickr user John Bracken, via Creative Commons.
The coronavirus crisis stands to dramatically reshape cities around the world. But the biggest revolutions in urban space may have begun before the pandemic.
Now more than ever, public transportation is not just about ridership. Buses, trains, and subways make urban civilization possible.
Places like New York, Miami and Las Vegas have a higher share of the workforce in jobs with close proximity to others, putting them at greater Covid-19 risk.
Will COVID-19 change how cities are designed? Michele Acuto of the Connected Cities Lab talks about density, urbanization and pandemic preparation.
What do we know so far about the types of places that are more susceptible to the spread of Covid-19? In the U.S., density is just the beginning of the story.


text:
Your roundup of all the hottest hot-stove items of the day (and whatever shit Ken Rosenthal is throwing against the wall). This is ... HOT FUCKING STOVE!!
• Meet Barry Zito's new lifelong yoga partner, Amber Seyer. The Giants lefty tied the knot with the former Miss Missouri this past weekend. We're sure she's looking forward to nursing Zito back from his assorted injuries for the next 50 years.
• So remember how the Marlins's offer to Albert Pujols was a bullshit PR stunt? We may have gotten that one wrong. In a meeting with Pujols'sesteemed agent, Dan Lozano, the Marlins apparently upped their offer to 10 years. The actual figures are still unknown, but it's probably time we start taking Miami seriously.
• Lozano had some meetings with the Cardinals and the Cubs, too.
• More bad news for Cardinals fans: The backup plan for losing Pujols may not be as foolproof as we thought it was.
• C.J. Wilson's old high school is really close to the Angels' ballpark. [ESPN Insider]
• Terry Francona will be doing Bobby Valentine's old job next season.
• Hanley Ramirez isn't happy about having to make room for Jose Reyes.
• The Blue Jays acquired closer Sergio Santos from the White Sox for a pitcher with some crazy minor league stats.
• Twins GM Terry Ryan is wheeling and dealing as if he never left Minneapolis.
• Manny Being Desperate.


text:
Retirement is a beginning, not an end
(NewsUSA) - Chances are, you know someone about to enter retirement. Between aging baby boomers and struggling businesses, many seniors find themselves leaving the workplace. And the numbers of new retirees are only going to rise -- nearly 6,000 Americans turn 65 every day.
Retirement is a big transition for a former working stiff, and many people struggle to determine their next step. After all, the retirement age of 65 was established in the late 1800s, when life expectancies were shorter -- today's retirees will live for decades after leaving the workforce.
And longer lives create more expenses. Many retirees will end up pursuing second jobs in order to meet expenses. Only half of all employees earn pensions, and the falling stock market wiped out many a retirement fund.
If you're planning -- or even attending -- a retirement party, you should keep these potential uncertainties in mind. For example, a person being forced into early retirement might not appreciate congratulations. It's more appropriate to express how glad you are to have known or worked with the retiree.
That said, it is still okay to celebrate by acknowledging the retiree's contributions. If you're selecting gifts for a retiree, choose something that will commemorate their work, such as a personalized wall plaque or pen holder.
Of course, retirees today often choose to stay active, pursuing new careers that suit their personal interests or involving themselves in volunteer work.
With this in mind, treat your coworker's retirement like a transition into a new and rewarding phase of life, rather than just an exit from the workplace. Talk to the retiree's spouse and friends to learn about their post-retirement plans. If they're planning on going back to school, for example, you might want to give them a gift certificate to a book store, as well as a gift that commemorates their contributions to your organization.


text:
The following 6 products are guaranteed to work in your 1710n printer:
By Dell
Product details
By Reman
Ask a Question
No questions have been asked for this printer yet. Why not ask the first one?
Write a Review
No reviews have been written for this printer yet. Why not write the first one?


text: I gotta agree with BuFu, Smith is a cocky ****, but I like it. If you can be TOUGH, then you can be cocky. I watched that hit about 5 times last night, and I just can't calm down at all, I am sooo pumped for next year. We easily have the best depth in the NFL at safety, and all of them hit like beasts. Is it August yet?


text:
With Porteus in Your Pocket, You're Good to Go
Jul 24, 2013 5:00 AM PT
Porteus Linux is an almost perfect portable distro that gives you a choice of the KDE4, Razor-qt, XFCE or LXDE desktops in both 32- and 64-bit versions.
Don't think that a live version of a Linux desktop with the ability to save configuration changes is better than an operating system fully installed to a hard drive? Think again.
Its persistent memory feature, unlike regular live distro sessions, lets you carry a complete Linux desktop with all of your files and special application settings in your pocket to run on any computer.
Porteus boots from a USB drive or other bootable external media in as little as 15 seconds. That booting time can take longer if you add an excessive number of software modules. If you boot from a DVD, the loading time of the Linux components will take up to a minute longer than from a USB drive.
Of course, booting times are dependent ultimately on your hardware. Regardless of how new or old your computer, Porteus is lightning fast, because it is optimized for speed and keeps what it needs in system RAM to reduce reading time.
Best of All Worlds
One of the coolest features with Porteus is its KDE desktop option. I do not know of any other portable Linux distro that crams KDE onto a stick.
The theory with designing a portable Linux distro is to make it lightweight enough to fit on bootable external storage devices with more limited storage capacity than a DVD. Typically, portable Linux distros run XFCE or LXDE-style environments.
I've gotten a lot of productivity value out of Puppy Linux and Knoppix Linux As good as these two portable distros are, Porteus is more flexible.
My initial experience with Porteus involves the recently released version 2.0, which is based on the Linux kernel 3.7.8. However, Porteus 2.1 RC2 is under development now, using kernel 3.9.4, which should offer even better flexibility with performance and hardware compatibility.
Different Family Line
Porteus is based on Slackware Linux. It has a sordid lineage. Porteus began with KDE 3 as the default desktop; it was a community remix of Slax, a now abandoned Slackware-based live CD. The lighter-weight desktops came along later as alternative environments.
There was a bit of a learning curve before I got comfortable with Porteus. Despite my familiarity with KDE, LXDE and Xfce environments, the Slackware core operations were keenly different from my Debian Linux roots.
My effort paid off quite handily, though. Porteus is packed with lots of features and an expansive software set. The longer I drove it around, though, the more quirks I needed to figure out. The user forums and ample online documentation smoothed my transition.
I am not at all saying that Slackware Linux or Porteus is harder to use than Debian or other Linux cousins. The default settings for Porteus and its included applications worked as expected. However, I am a tinkerer and a fiddler who has to add specialized applications and tweak all the available options.
Standard Fare
Out of the box, Porteus has a smart collection of applications to satisfy typical users. I mostly worked with the KDE desktop. Some of the applications are different in the other desktop options, but a mixture of KDE and XFCE/LXDE apps was available and worked fine in all desktop environments.
For example, Porteus comes with the Firefox Web browser plus some half dozen standard Linux Internet and networking tools. The Graphics apps include Okular, Gwenview, Image Viewer, Paint and screen capture program.
Porteus has an impressive complement of multimedia apps as well, including Audio CD Ripper, Audio Player, ISO File Master, GNOME and SM media players, Pburn, Sound Mixer and a webcam program.
The office applications out of the box were the least impressive collection of apps. They contained no full service office suites. The only text editor installed was KWrite.
From Sparse to Glut
Especially where the KDE desktop comes into play, applications such as Konquerer, Calligra and KWord are missing. That is in keeping with the goal of holding the Porteus footprint to under 300 MB.
Adding what is initially missing is relatively easy with the Porteus Package Manager, however. I added the Google Chrome Web browser, Abiword, LibreOffice and the Geany Text Editor to complete my working needs.
Normally, the word processing and text editing applications install with the spelling checker language modules intact. Not so with Porteus. Even when I added those modules and activated them, no dictionary was evident.
I solved that problem with LibreOffice by adding the additional language pack for English as a plugin through its Tools/Language/Extension Manager menu. Still, Abiword and Geany are illiterate with no dictionary access. I hope the Porteus forum can help me solve that issue.
Powerful PPM
The Porteus Package Manager is a heavy duty installer that serves as a cross-distro package converter. It has modules for accessing repositories for its own apps along with Slackware, SlackBuild, Salix, Alien and Debian.
The PPM resolves dependencies from across the repositories. It creates a package module rather than doing a conventional installation.
So you can use PPM to activate just the modules you need for a particular session and deactivate them when not needed. To uninstall a software package, just delete the module using a file manager.
Starting It
When Porteus boots, the first screen you see is the list of options. There you select the graphics mode, which is either KDE, XFCE or LXDE.
The third loading option is the Always Fresh mode. This option starts Porteus with its original values and does not keep any changes you make for the next session.
Alternatively, you can arrow down to the Copy to RAM mode. This option places Porteus completely in RAM, provided you have at least 768 MB. It takes a bit longer to get to the desktop with this choice, but Porteus runs on steroids this way.
Yet another loading option is Text Only mode. This runs Porteus from a command prompt only. You can also load Porteus with a PXE server feature. This allows you to boot Porteus on other computers over a network.
Booting Cheats
If you leave the Porteus DVD or bootable USB in a computer, you can bypass the Porteus booting process without removing them. Just select the option to boot from the first hard drive. This boots the computer's resident OS installed on the hard drive.
It is easy to make changes on the fly when Porteus boots by entering cheat codes from the splash screen. After you select the booting option described above, hit the Tab key instead of the Enter key to place the cursor on a command line.
Then enter the desired cheat code to set the parameters for the computing session. Hit the Enter key when done to complete the loading process.
You can enter as many cheat codes as desired. Just separate each one with a space. The cheat codes override default settings in the config file. That file has the scripts that coincide with the cheat codes you enter.
Have It Your Way
Puppy Linux and Knoppix use a similar cheat code system to load configuration options on the fly when booting. However, the cheat codes for Porteus are more like natural phrases, so they are easier to use.
I boot into my Porteus sessions from a USB drive that holds not only the Porteus OS but all of the software modules that I added and all of the OS settings, so I have a uniform user experience on every computer I borrow to run Porteus Linux.
For example, /mnt/sdb1/porteussave.dat tells Porteus to load all the configuration settings and save all changes to the OS in that file. After a space I enter: from=/dev/sdb1 so Porteus always reads from the faster USB drive if I also left the DVD in the optical drive. Last, I use the copy2ram cheat code to put all of the OS into memory on my desktops and laptops that ooze 4-8 GB of RAM.
I keep all of my working documents, audio and graphic files on a separate large-capacity USB drive. This gives me access to all of my data on whatever computer and OS I use.
Bottom Line
Porteus is such a fine-tuned Linux distro, it can easily replace whatever else you have installed. You can not install Porteus on a hard drive. However, you can do a frugal installation that lets you use a GRUB entry to boot the live environment without needing the DVD or USB bootable device.
As an added security measure, Porteus loads in guest mode. You can override that with a cheat code to run as an admin. You can also enter the admin password when accessing privileged areas such as config settings and the PPM. Just think "root user" and type in "toor" when prompted -- and yes, you can change that to something else permanently by editing the config file.
Want to Suggest a Linux Application for Review?
Is there a Linux software application you'd like to suggest for review? Something you love or would like to get to know?
Please send your ideas to me, and I'll consider them for a future Linux Picks and Pans column.
And use the Talkback feature below to add your comments!


text:
Model Jourdan Dunn has taken it upon herself to tell the truth about racism, which goes on the runway.
Dunn is taking a stand against the fashion industry and wants to reveal the truth.
"I want to talk about what goes on. A lot of people are scared to speak up. People think it's all glamorous and good and that all models get treated the same, but there is still a lot of bulls**t that happens. I speak up," Dunn told the Guardian newspaper's the Fashion magazine.
The model feels that not being allowed to walk for a show, because of the skin colour, is wrong.
"I wanted to make a point, but not a dig. Girls get cancelled last minute all the time, but at least it wasn't because of my skin tone. Which I often get in Paris," she said.
A mother of a three-year-old son, Dunn feels that big shots in the fashion industry should try to make a change.
"The people who control the industry, they say if you have a black face on a magazine cover it won't sell, but there's no real evidence for that."
"It's lazy. You always hear, 'There aren't enough black models', which is bulls**t. It's all about these dead excuses," she said.
Model Jourdan Dunn has taken it upon herself to tell the truth about racism, which goes on the runway.


text:
Handgun Vaults - Biometric Smart Vaults - HDX-150 Smart Vault
Product Description
Safely secure your valuables or handgun in the new Home Defender (HD) Series by Liberty Safe. The HDX-150 Smart Vault allows for quick and secure access by using our 5th Generation BIOMETRIC finger swipe technology. This is the most reliable biometric entry system available, with supreme accuracy and the lowest fail-rate on the market. Speed counts! Entry using the Biometric swipe can be obtained in 1 SECOND when utilizing the AC adapter (optional) and under 2 seconds (1.63 to be exact) with the 9v battery (included). The HDX-150 Smart Vault can accommodate 15 different fingerprints. This Liberty biometric gun safe is designed to be portable and can easily fit in a drawer or automobile. A security cable is included, an optional AC adapter is also available.
The HDX-150 Smart Vault has been designed to safely store your firearms until you need it. The Heavy Duty 14-gauge steel vault has a reinforced latch system that is specifically built to resist pry attacks and other attempts to gain entry. Liberty engineers and tests everything that we build so that you can trust your vault to protect your firearms and your family.
Liberty is known for quality and stands behind the HDX models (including the Liberty HDX-250 smart vault as well as the HDX-350) by offering a 5-year replacement warranty on any defects.
Speed and Security when you need it most. Don't settle when protecting your family...trust the best, trust a Liberty! Made in the USA!
- The most reliable BIOMETRIC system available
- Quick and Secure finger swipe access
- 15 Fingerprint Memory
- Tamper Resistant Design
- Lighted Interior
- Tough 14-gauge Steel Construction
- Fits most handgun sizes
- Key Backup
- Portable, security cable included
- 5-year warranty
- Grey Marble Finish
Exterior Dimensions: 2.25" x 12.5" x 8.75" (H x W x D)
Interior Dimensions: 1.5" x 10.75/6.25" x 8" (H x W x D)
Weight: 9.5 lbs
*This is a California-approved firearm safety device that meets the requirements
of Penal Code section 23655 and the regulations issued thereunder.
*Free standard shipping on accessory orders over $25 is available in the contiguous 48 U.S. states only.
**Made in the U.S.A. from U.S. and Global Parts.


text:
A little girl with a serious medical condition is making amazing progress after using what many believe is a breakthrough treatment option.
As a last resort, her family tried a non-euphoric strain of medical marijuana for their 10-year-old daughter's relentless seizures.
And it worked.
A video of Charlotte Figi that shows her during a seizure is credited for revolutionizing the way the world views the cannabis plant. Traditional treatments for her uncontrollable seizures almost killed the child, until her mother turned to medical marijuana.
"Her seizures were instantly abated, so her 300 weekly seizures are down to zero her first week after that first dose," said Paige Figi, Charlotte's mother.
In 2014 the family traveled to Florida to help push for the legalization of Charlotte's Web, a non-euphoric strain of marijuana.
Now, years later it's available at the very first family medical cannabis clinic in Tampa.
Parents with children who suffer seizures have moved their families to states like Washington and Colorado to gain better access to medical marijuana.
"In particular the CBD that's found in the low THC medical cannabis that's now for people with seizures and people with muscle spasms and people with cancers helping people across the country and now in Florida, we have the opportunity to help people out," said Dr. David Berger, a pediatrician.
Berger heads up the clinic and said many parents are seeking out safer alternatives to traditional drugs and turning to medical marijuana.
"It's an incredibly safe profile. You can't get high from taking a product that just has the CBD in it - and that's really an important thing because a lot of the patients that I've talked to so far especially those with chronic muscle spasms who are on pain medications those people who are really concerned about getting addicted to those types of medications," said Berger.
Berger orders tinctures and capsules for his young patients because it's easier and safer to control dosages. He also treats adults at the clinic, and other forms are available.


text:
3/4 Sleeve Shirt Featuring Rhinestone CSA Logo
This 3/4 vneck shirt is made of ringspun cotton and great for Mom.
If you are adding personalization please remember to type the exact way you want it spelled in the comments section of the checkout process.
Personalization is centered under the logo.
Click second image for proper sizing.


text:
Researchers say Xbox technology is fair game for engineering education09/27/2011
Dr. Yang Yun, associate professor of biomedical engineering, demonstrates the latest technology of using the Kinect™ sensor as a natural interface to the computer. He and other UA researchers will apply the technology to engineering education.
A team of University of Akron researchers is about to show how Microsoft's Kinect™ sensor device for Xbox can transition from the family room to the classroom. Dr. Yang Yun, associate professor of biomedical engineering; Dr. Philip Allen, professor of psychology; and Dr. Yingcai Xiao, associate professor of computer science, are developing an educational tool that uses Kinect™ to noninvasively stimulate the visual center of students' brains to help them comprehend engineering principles.
The National Science Foundation awarded the researchers $150,000 for the project, titled "Interactive Learning to Stimulate the Brain's Visual Center and to Enhance Memory Retention."
During the project's two-year span, the researchers will use Kinect™ to capture students' gestures to allow them to interact virtually and in real-time with educational materials. The system's natural interface, which connects visual and motor domains, befits engineering education better than traditional language-based teaching with visual supplementation, say the researchers.
interactive visual approach helpful to students
"The existing teaching method requires students to process inherently visual-spatial information into language-based codes," says Allen, who adds that this methodology also disrupts the brain's visual component with other inputs, such as oral information, and lowers learning performance. In contrast, the proposed system presents learning materials interactively with rich details, establishing the interactive visual approach as the primary manner of learning.
Dr. Philip Allen, left, professor of psychology; Dr. Yang Yun, associate professor of biomedical engineering; and Dr. Yingcai Xiao, associate professor of computer science, are developing an educational tool that uses Kinect™ to stimulate the visual center of students' brains to help them comprehend engineering principles.
"Our project is a series of 'video games with a purpose,'"Allen says. "We hope that it will not only be easier to learn and remember information encoded in this manner, but it also will make engineering exciting to more students."
The project integrates biomedical engineering education with computer science and biological mechanisms associated with cognition and memory. Kinect™ is a new generation of HCI (human computer interface) termed NUI (natural user interface). Equipped with a 3D camera, it captures users' motions and tracks their gestures, Xiao explains.
"With our system, students will be able to use their hands to grab virtual viruses and use their feet to kick virtual bacteria. The full-body interaction allows students to travel into cells to explore various cell subunits and to dive into nanosized molecules, such as DNA and enzymes, to figure out their structures," Xiao says.
Learning process could be transformed
When applied to engineering education, this new tool can improve instructors' ability to teach effectively and positively transform the learning process for students, especially for at-risk students, according to Yun.
"If our research team appropriately designs and integrates the education materials into the Kinect™ system, the learning experience can be similar to playing games such as World of Warcraft and Halo. Students will have a natural affinity toward learning and will engage, interact and participate with the educational materials," Yun says.
The researchers will begin their study in January by adopting Kinect™ into two existing UA biomedical engineering courses related to gene therapy, one freshman-level class and the other, senior-level. The researchers will add a third class that uses and promotes Kinect™ as a research and teaching tool.
Their goals are not only to improve educational instruction for K-12 and undergraduate students, but also to encourage students to choose a major in engineering. After they develop the teaching tool, the researchers plan to distribute 18 Kinect™ systems and companion educational materials to McKinley, North and Firestone high schools.
"An important mission of our research team is to reach students from economically disadvantaged backgrounds for whom a career in engineering has traditionally been out of reach," Yun says.
Media contact: Denise Henry, 330-972-6477 or firstname.lastname@example.com.


text:
24 June 2013 at 12.29pm | Comment on this article
The Story Begins…
As a young man Simon Boccanegra suffers appalling misfortune: his lover Maria dies and their baby daughter disappears. Many years later Boccanegra, now Doge of Genoa, is reunited with his daughter. But their happiness is threatened by Boccanegra's enemies, including the man who helped him win power.
A Renaissance Dream
Elijah Moshinsky's production pays homage to Renaissance architecture and painting without aiming for total realism. The Council Chamber wall in Act I scene 2 contains a passage from The Chronicles of Genoa about the historical Boccanegra, written long after his death – Boccanegra is part of history even while alive. The sea is a dominant presence, represented with delicate blue lighting. Moshinsky envisages it as a metaphor for Boccanegra's death at the end of the piece.
An Unsuccessful First Version
The first version of Simon Boccanegra had its world premiere in 1857 at La Fenice, Venice. The librettist was Verdi's regular collaborator Francesco Maria Piave, the source a play by Antonio García Gutiérrez. The opera was not a success. Verdi's publisher Ricordi suggested that the composer make some revisions, but Verdi was non-committal. Many years later, Ricordi introduced Verdi to Arrigo Boito, who was keen to work with the composer as a librettist. Verdi insisted that their first task should be to revise Boccanegra.
A Second Chance
Verdi and Boito's revisions of Simon Boccanegra included an entire new scene at the end of Act I, set in the Council Chamber, in which the Doge's nobility is brought to the fore. The revised opera's premiere at La Scala, Milan, was well received. Although it took Boccanegra time to become established in the repertory, it has steadily grown in popularity, particularly in recent years. In 2011 there were three new productions in Europe plus several revivals.
An Extreme Simplicity
Verdi aimed for a plain, almost austere style in Simon Boccanegra, reflecting the harsh political world of Renaissance Genoa. The stark simplicity of much of the writing
makes the opera's moments of tenderness – Boccanegra's duet with Amelia in Act I, Boccanegra's duet of reconciliation with Fiesco in Act III, the closing ensemble of the opera – all the more striking and poignant.
Simon Boccanegra runs from 27 June – 16 July. Tickets are still available.
The production is staged with generous philanthropic support from Mrs Susan A Olde OBE, Afiya and Timur Kuanyshev and the Verdi Syndicate.


text:
A team of scientists launched an instrument-laden rocket into northern lights display on Saturday, February 18th. The two-stage Terrier-Black Brant rocket was blasted from the Poker Flat Research Range in Fairbanks, Alaska. Funded by the NASA, the mission is studying electrical activity in the aurora borealis and the likelihood it's interfering with GPS and other signals.
via Universe Today


text:
Hello and welcome to the new HYIPsTalk.com Forum! We decided to switch from vBulletin to XenForo. In this upgrade process I also removed a ton of spam and old topics. If you see spam please use the Report link available on each post.
From now on there will always be a moderator present on the forum. If you have any problems or questions you may start a conversation with user hyipstalk.
- Last Activity:
- Oct 16, 2013
- Joined:
- Feb 21, 2012
- Messages:
- 1,229
- Likes Received:
- 0
- Trophy Points:
- 36
Share This Page
Active Member
- danke was last seen:
- Oct 16, 2013
- Loading...
- Loading...


text:
Pilot and Feasibility Study of Hematopoietic Stem Cell Gene Transfer for the Wiskott-Aldrich Syndrome
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT01410825
Recruitment Status : Active, not recruiting
First Posted : August 5, 2011
Last Update Posted : January 23, 2020
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
The Wiskott-Aldrich Syndrome (WAS) is an inherited disorder that results in defects of the blood and bone marrow. It affects boys because the genetic mistake is carried on the X chromosome. Normal people have blood cells called platelets that stop bleeding when blood vessels are damaged. Boys with WAS have low numbers of platelets that do not function correctly. Boys with WAS are thus at risk for severe life-threatening bleeding. A normal immune system is made of special blood cells called white blood cells, which protect against infection and also fight certain types of cancer. In WAS, these white blood cells don't work as well as they should, making these boys very susceptible to infections and to a form of blood cancer known as lymphoma. The abnormal white blood cells of patients with WAS also cause diseases such as eczema and arthritis. Although WAS can be mild, severe forms need treatment as early as possible to prevent life-threatening complications due to bleeding, infection and blood cancer.
Over the past decade, investigators have developed new treatments based on the investigators knowledge of the defective gene causing WAS. The investigators can now use genes as a type of medicine that will correct the problem in the patient's own bone marrow. The investigators call this process gene transfer. The procedure is very similar to a normal bone marrow transplant, in that the old marrow is killed off using chemotherapy, but is different because the patient's own bone marrow is given back after it is treated by gene transfer. This approach can be used even if the patient does not have any matched donors available and will avoid problems such as GVHD and rejection. The investigators wish to test whether this approach is safe and whether gene transfer will lead to the development of a healthy immune and blood system.
|Condition or disease
|Wiskott-Aldrich Syndrome
|Biological: Retrovirus-mediated gene transfer
|Phase 1 Phase 2
Wiskott-Aldrich syndrome (WAS) (OMIM 301000) is a rare X-linked immunodeficiency caused by mutations in a single gene, WAS, mapping to Xp11.22-Xp11.3 and coding for the Wiskott-Aldrich Syndrome Protein (WASP) 1. WASP is a critical regulator of actin signaling with expression limited to hematopoietic cells, and thus is required for multiple functions including T cell activation, dendritic cell migration and podosome formation, and B cell terminal development and function. WAS is characterized by microthrombocytopenia, recurrent infections, eczema and associated with a high incidence of auto-immunity and of lymphoid malignancies. Classic or severe WAS, is generally observed in patients with nonsense mutations or insertions/deletions resulting in frameshift or splice-site mutations or missense mutations and resulting in unstable protein 2. With few exceptions, WASP-negative patients have classical disease. Affected patients have a severely reduced life expectancy.
Currently, the only curative option for WAS patients is hematopoietic stem cell transplantation (HSCT). This treatment is most successful when an HLA-identical sibling or matched unrelated donor is available and results in correction of microthrombocytopenia and immune dysfunction, even when stable mixed chimerism occurs. However, even patients undergoing matched HSCT can suffer from considerable morbidity and mortality due to graft versus host disease (GVHD) and many patients lack an HLA-identical donor. The outcome of mismatched related HSCT is consistently poor with survival of approximately 50%. Gene transfer is an attractive alternative treatment for WAS. Successful gene transfer using autologous gene-corrected HSC would overcome clinical complications linked to GVHD and its treatment. Furthermore, in contrast to allogeneic HSCT, gene transfer would not be limited by the availability of compatible donors. Several lines of evidence indicate that partial reconstitution with gene corrected cells may be sufficient to ameliorate the disease.
We propose here a Pilot and Feasibility study of ex vivo gene transfer using a lentiviral vector (LV) to transduce autologous bone marrow derived CD34+ HSC. Cells will be infused into patients conditioned with cytoreductive chemotherapy. Our collaborating investigators in Europe have developed a LV encoding the human WAS cDNA under control of the WAS promoter and pseudotyped with the Vesicular Stomatitis Virus glycoprotein (VSVg) envelope. This w1.6_hWASP_WPRE (VSVg) LV (abbreviated as w1.6W) has been shown to be efficacious in both in vitro and in vivo preclinical models. Safety including cellular toxicity, insertional mutagenesis and tumor formation has been studied by a number of methods including: 1) a sensitive in vitro transformation assay, 2) toxicity studies in transduced human CD34+ cells, 3) examination of the insertional pattern in transduced murine cells, and 4) long-term observation and secondary transplant studies in mice. In the United States, we plan to enroll 5 boys with classic WAS who lack a matched related or unrelated donor. Parallel studies (not under our Investigational New Drug application) using the same LV produced in the same facility, Genethon, will be conducted in London, UK (5 subjects) and Paris, France (5 subjects). The primary objective will be to demonstrate feasibility and safety. The secondary objective will be to assess therapeutic efficacy.
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|5 participants
|Intervention Model:
|Single Group Assignment
|None (Open Label)
|Primary Purpose:
|Official Title:
|Pilot and Feasibility Study of Hematopoietic Stem Cell Gene Transfer for the Wiskott-Aldrich Syndrome
|Study Start Date :
|July 2011
|Estimated Primary Completion Date :
|January 2022
|Estimated Study Completion Date :
|July 2023
Experimental: Gene transfer
Open label single arm study
Biological: Retrovirus-mediated gene transfer
Two procedures: 1) Bone marrow harvest from the patient's posterior iliac crests or collection of peripheral blood stem cells via apheresis procedure. 2) One time infusion of patient's transduced bone marrow cells.
- Safety of infusion of transduced cells [ Time Frame: 5 Years ]Safety of infusion of transduced cells as rescue of hematopoiesis after conditioning (hematopoietic recovery as assessed by absolute neutrophil count (ANC) above 0.5 x 109 /l for three consecutive days, achieved within 6 weeks following infusion).
- Engraftment of genetically corrected T cells [ Time Frame: 5 Years ]Engraftment of genetically corrected T cells in peripheral blood (as assessed by evidence of vector sequences in >1% of CD3+ T cells) at 6 months.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|3 Months to 35 Years (Child, Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
Confirmed molecular diagnosis by DNA sequencing and either
- absence of the WAS protein by flow cytometry OR
- clinical score 3-5
- Age 3 months to 35 years
For subjects < 5 years of age:
- Lack of HLA-genotypically identical bone marrow donor.
- Lack of a 9/10 or 10/10 molecularly HLA-matched unrelated donor after 3 months of searching.
- Lack of a 6/6 molecularly HLA-matched cord blood donor of adequate cell number after 3 months of searching
For subjects 5 years of age or older:
a.Lack of HLA-genotypically identical bone marrow donor.
Subjects who have undergone allogeneic transplant previously must additionally have:
- Failure defined as <5% donor T cell engraftment and
- Contraindication to re-use of the same donor due to severe GVHD or non-availability.
- Parental/guardian/patient signed informed consent
- Willingness to return for follow-up during the 5 year study period.
Adequate organ function and performance status
- Performance status ≥50% (Lansky play for age <16 years, Karnofsky for age ≥16 years)
- Left ventricular ejection fraction >40% or shortening fraction >25%
- Bilirubin ≤ 2.0 mg/dL
- Measured creatinine clearance or GFR by nuclear medicine study ≥40 ml/min/1.73 m2
- DLCO (corrected for hemoglobin), FEV1, FVC >50% of predicted; if age < 7 years, then oxygen saturation >92% on room air
Exclusion Criteria:
- Contraindication to bone marrow harvest, or to administration of conditioning medication.
- Known positive HIV serology or HIV nucleic acid testing.
- Other uncontrolled infection.
- Active malignancy other than EBV lymphoproliferative disease.
- Known myelodysplasia of the bone marrow or abnormal bone marrow cytogenetics
- Congenital cardiac disease with congestive heart failure
- Oxygen dependence at baseline
Any other condition that, in the opinion of the Investigator, may compromise the safety or compliance of the patient or would preclude the patient from successful study completion. This may include but is not limited to:
- Severe deterioration of clinical condition after collection of cells but before infusion of transduced cells
- Documented refusal or inability of the family to return for scheduled visits
- Other concerns about unwillingness or inability to comply with protocol requirements
- Unforeseen rare circumstances such as sudden loss of legal guardianship
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01410825
|United States, Massachusetts
|Children's Hospital Boston
|Boston, Massachusetts, United States, 02116
|Principal Investigator:
|Sung-Yun Pai, M.D.
|Boston Children's Hospital
|Responsible Party:
|David Williams, Chief of the Division of Hematology/Oncology, Boston Children's Hospital
|ClinicalTrials.gov Identifier:
|Other Study ID Numbers:
|First Posted:
|August 5, 2011 Key Record Dates
|Last Update Posted:
|January 23, 2020
|Last Verified:
|January 2020
Gene Transfer
Gene Therapy
Pathologic Processes
Wiskott-Aldrich Syndrome
Blood Coagulation Disorders, Inherited
Blood Coagulation Disorders
Hematologic Diseases
Hemorrhagic Disorders
Leukocyte Disorders
Genetic Diseases, Inborn
Genetic Diseases, X-Linked
Immunologic Deficiency Syndromes
Immune System Diseases


text:
Our site for journalists.
Journalists will find further information and latest updates here. We would also be happy to put you in touch with the right contacts for interview and discussion on the topics of languages, intercultural training and business seminars.
- Latest press releases
- Corporate profile
- Press archive (press releases in chronological order)
- Press photos


text: PegaWorld 2018 replays Geared towards different industries, products, and a host of hot topics, PegaWorld 2018 has something for everyone. Check out this year's session replays below. Showing 1 result(s) for Government, CRM, and Marketing Automation. (Clear filters) Search Apply Show search filters Filter Sessions Days Monday, June 4 (1) Session Type Customer Case Study (1) Topics Analytics (1) BPM (1) Case Management (1) Customer Service (1) Robotic Automation (1) CRM (1) Marketing Automation (1) Industry Cross-Industry (26) Financial Services (7) Healthcare (2) Communications Service Providers (1) Insurance (1) Manufacturing (1) Other Industry (1) Utilities (1) Government (1) Product Customer Service (1) Cancel Close search filters Customer Case StudyHow a Social Services Organization Works with Current and Former Offenders to Reduce Crime ACSO is a nonprofit organization focused on supporting clients in, or at risk of... Download this presentation


text:
Moderator: Cartographers
Nola_Lifer wrote:It would be cool to see some mountains and rivers on this one or some sort of topography.
onbekende wrote:Hello, its your friendly neighbourhood occational, sporadic, hardly around, sometimes, ghostly poster on maps. Yo cairnswk
In light of your Rail Asia map I read about this one, popped in to see how it is and throw in totally unwanted and mostly ignorable advice. Will do the usual bonus calc and general observations and will do them per line/letter (not nitcpicking every detail). The bonus I calc is my old formula (slightly adjusted) of: [( #terts * 1.5 ) + ( #terts to defend * 4 ) + ( #terts that can be attacks from it * 2 ) + ( #continents adjecent * 1 )] / 9 => #bonus
So we got an obvious GNSET-stronghold and a lesser HODUKM stronghold that is an expantion stronghold (first H => HO => HODU => HODUKM)
greenoaks wrote:the red in the legend is really blurry, is that the way you want it?
koontz1973 wrote:Quick move for you. Do not forget to PM isaiah40 for supersize.
cairnswk wrote:greenoaks wrote:the red in the legend is really blurry, is that the way you want it?
No, greenoaks and thanks for dropping in...belated Xmas wishes.
this is possibly from the background colour, so will see about adjusting those next version.
Funkyterrance wrote:The closest I ever came to crying when looking at a new map. You don't need to know the colors to read it! It's a beautiful thing. If this system of map labeling could be applied to all maps you would be the hero of chromatically challenged players everywhere!
I have to admit that at first glance I let out a sigh when I saw all the subtle color changes but was oh so pleasantly surprised when I noticed they didn't matter. The map could appear like Das Schloss to me but I wouldn't care as long as I could figure the bonuses easily like I can on this one.
On a small side note, I would prefer that the photos were run through a paintbrush filter or something so they matched the vibe of the map better but this of course is purely a creative viewpoint.
greenoaks wrote:i like the 'red' much better now.
greenoaks wrote:i would be interested to see what FT is suggesting with the photos however i do like them the way they are.
i can't find anything to nitpick you about.
JBlombier wrote:I think the E-bonus is a bit too isolated. It'll be hard to reach for an elimination if someone has the dropped on RGS.
I've always liked Railmaps, so I hope you're gonna make another awesome one.
koontz1973 wrote:...
Falkland islands, why are they on the map? They do not have railways and certainly not owned by anyone in the region.
koontz1973 wrote:cairns, the new photo look is nice. It brings in a sense of the older maps with the shapes but the frame can do with a lot of love (early days I know but just want to get my opinion in). Which leads me onto my next point, the terminus, the shape, or lack of one is different and nice (I always like different). But does B connect to L and N to G. This will need to be put onto the map.
To sort the E bonus out, why not connect PTM to SCB?
Overall, a good update.
koontz1973 wrote:Heard anything about the size application yet?
koontz1973 wrote:cairns, 2 things before this map can go forward.
- Firstly the sizing issue. This is a big concern at the moment and it looks like it will not be needed for this one. You have a 1000 in height but you need to get it down to the 800 limit. This should really not be to much hassle. It will make the map more square but this is a must right now.
- Secondly, this is going to be the last one allowed. That means no Rail Antarctica or Rail Mars etc.
Users browsing this forum: No registered users


text:
Generation Education
Any company's success is based on its capable and motivated staff members and their willingness to actively apply all their knowledge and abilities. To stay successful, we need motivated young employees – employees who develop a fascination with medical progress and want to make a difference and shape the future of medicine in an important field. As a pioneer in endoscopy and one of the most innovative companies in the industry, we set high standards for ourselves – and consequently for our employees. Therefore, vocational training at KARL STORZ is conducted with foresight and a focus on long-term success. One of the company's principles is to train staff ourselves if possible, at all levels and in all functions. This allows us to familiarize staff members at an early time with the principles of the KARL STORZ quality philosophy and to optimally support and prepare them for their roles within the company. Therefore, KARL STORZ offers apprenticeships in a wide range of industrial and technical as well as commercial professions, including several cooperative university study programs.
The greatest potential, however, arises wherever years of experience meets new knowledge. Therefore, continuing education and training is an important element in mastering future challenges, particularly for a technology-oriented company like KARL STORZ, and it is therefore a high priority.


text:
This website uses "cookies". In compliance with the General data protection regulation (GDPR) we ask that you chose to accept or decline cookies which is a small text file containing information.
We use cookies for pure technical reasons in order to improve the user experience, however we do not store any personal data. You are able to change your settings at any time.
I accept cookies I decline cookies
Akuta fel Ultuna/Green Innovation Park
Professional service booker.
Please register.
© Akademiska Hus 2019 | Privacy Policy | Cookies | E-mail: firstname.lastname@example.com | Tel: +46 (10) 557 24 00


text:
Hi there,
I have this piece of code:
XmlDocument doc = new XmlDocument();
// Initially value "<ParentNode></ParentNode>"
doc = mngr.XmlDoc;
XmlDataProvider xmlDP = new XmlDataProvider();
xmlDP.Document = doc;
xmlDP.XPath = "/ParentNode/ChildNode";
CollectionViewSource collection = new CollectionViewSource();
collection.Source = xmlDP;
collection.SortDescriptions.Add(new SortDescription("ChildNodeName", ListSortDirection.Ascending);
Binding bnd = new Binding();
bnd.Source = collection;
listbox.SetBinding(ListBox.ItemsSourceProperty, bnd);
Sample Xml Document:
Case 1:
When I run my application (No item in the list box), "SOMETIMES" the listbox would have a ListBoxItem which is in XmlDocument. So when I do listbox.Items[0].InnerXml, it would return "<ParentNode></ParentNode>".
My expectation is that it would not generate any item because the XPath specified is " /ParentNode/ChildNode" which obviously not XmlDocument in this case.
Case 2:
When I run my application (Atleast 1 item in the list box), the listbox would have a ListBoxItem which is in XmlNode. So when I do listbox.Items[0].OuterXml, it would return "<ChildNode><ChildNodeName/></ChildNode>".
This is correct.
Please help.


text:
Beautiful to have in the garden or the house
We currently accept Visa and Mastercard or if you already have a paypal account, you can make a payment directly from your account. You do NOT need to have a PayPal account to purchase from our site. Simply follow the checkout steps on PayPal's secure website.
No, you are not required to have a PayPal account to purchase products on our site. You can input your billing details onto PayPal's secure website to complete your purchase.
All our payments are processed by PayPal who provide one of worlds most secure payment platforms, with over a decade as a leader in online payments.
Absolutely, you can call us directly on 01803 833739 and we'll be more than happy to process your payment over the phone.
Privacy Policy
Copyright © 2020 A Vintage Garden